EBI Dbfetch

ID   AY942653; SV 1; linear; genomic DNA; STD; FUN; 1804 BP.
XX
AC   AY942653;
XX
DT   09-APR-2005 (Rel. 83, Created)
DT   27-FEB-2007 (Rel. 90, Last updated, Version 2)
XX
DE   Candida glabrata strain IHEM 21231 C24 sterol methyltransferase (ERG6)
DE   gene, complete cds.
XX
KW   .
XX
OS   Candida glabrata
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   mitosporic Nakaseomyces.
XX
RN   [1]
RP   1-1804
RX   DOI; 10.1128/AAC.01510-06
RX   PUBMED; 17158937.
RA   Vandeputte P., Tronchin G., Berges T., Hennequin C., Chabasse D.,
RA   Bouchara J.P.;
RT   "Reduced susceptibility to polyenes associated with a missense mutation in
RT   the ERG6 gene in a clinical isolate of Candida glabrata with pseudohyphal
RT   growth";
RL   Antimicrob. Agents Chemother. 51(3):982-990(2007).
XX
RN   [2]
RP   1-1804
RA   Vandeputte P., Bouchara J.-P.;
RT   "Polyene resistance in Candida glabrata";
RL   Unpublished.
XX
RN   [3]
RP   1-1804
RA   Vandeputte P.;
RT   ;
RL   Submitted (23-FEB-2005) to the EMBL/GenBank/DDBJ databases.
RL   Laboratoire de Parasitologie-Mycologie, Centre Hospitalier Universitaire
RL   d'Angres, 4 rue Larrey, Angers 49000, France
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1804
FT                   /organism="Candida glabrata"
FT                   /strain="IHEM 21231"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:5478"
FT   gene            <492..>1610
FT                   /gene="ERG6"
FT   mRNA            <492..>1610
FT                   /gene="ERG6"
FT                   /product="C24 sterol methyltransferase"
FT   CDS             492..1610
FT                   /codon_start=1
FT                   /gene="ERG6"
FT                   /product="C24 sterol methyltransferase"
FT                   /db_xref="GOA:Q6FRZ7"
FT                   /db_xref="InterPro:IPR013705"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q6FRZ7"
FT                   /protein_id="AAX73200.1"
FT                   /translation="MSESELRQRQAEFTKELHGEGAESRTGLTALLSKNRNAQREAVSK
FT                   YLRHWDGKTDKEAEDRRLEDYNEATHSYYNVVTDFYEYGWGSSFHFSRFYKGENFQAAM
FT                   ARHEQYLAYMAGIKKGDLVLDVGCGVGGPARTIARFTGCNIIGLNNNDYQIQKAKYYAK
FT                   KYNLQDHMDFVKGDFMNMEFEPNSFDKVYAIEATCHAPKLEGVYGEIYKVLKPGGTFAV
FT                   YEWVMTENYDENNEEHRKIAYEIELGDGIPKMFTVDVAKQALKNVGFEVEVSKDLADED
FT                   DEIPWYYPLTGEWKYVQSLSDIATFFRTSYFGRKFTNCMVSIMEKVGVAPQGSVEVTAA
FT                   LENAAVGLVEGGRKKLFTPMFLFVAKKPEDAK"
XX
SQ   Sequence 1804 BP; 497 A; 399 C; 406 G; 502 T; 0 other;
     gaatttgtta cccgcagtgg tggagggggg tgctcgttgc ttttcgccct aagagagtgc        60
     ttcacaaggg atcccacgga aggggttttc tctgctgcta ttgccagtat tcttattgta       120
     gtattctatt gttcttattg ttggtctatt gttcttattg ttctaattct attgcaatcc       180
     tctgattcga gctcgaagat gtaaattgtc tcgtttactc ccttactccc cccgtcaaca       240
     ccctgcagtg gattgttact gcatctgcaa gcaagaaaaa aaattgcgaa aactcgttta       300
     gcccttcgta ccctttctgc tcaaatctcg gaagttatcg ggtaaacatc gcaaattttt       360
     tctggacagc tctattatat atattggtaa agacaatata cagtttattg tgctcttgac       420
     gtctctaaag cgtataacag aaaatatatc aaggaattga aattctcccg atactaatac       480
     agaaggaaaa gatgtctgag tcggaattga gacagagaca agctgagttc accaaggaat       540
     tgcacggtga aggtgccgag agcaggaccg gtttgaccgc gttgctgtcc aagaaccgta       600
     acgcccaacg tgaagctgtt tccaagtact tgagacactg ggacggtaag accgacaaag       660
     aggccgagga ccgtcgtttg gaggactaca acgaggccac tcactcctac tacaacgttg       720
     tcacggactt ctacgagtac ggctggggtt cctctttcca cttctcccgt ttctacaaag       780
     gtgagaactt ccaagccgcc atggctcgtc acgaacagta cttggcatac atggccggta       840
     tcaagaaggg tgacctagtg ctggacgtcg gttgcggtgt cggtggccct gcccgtacca       900
     tcgccagatt caccggctgt aacatcatcg gtctaaacaa caacgactac cagatccaaa       960
     aggctaagta ctacgccaag aagtataact tgcaagacca catggatttc gttaagggtg      1020
     actttatgaa catggagttt gagccaaatt ccttcgacaa agtgtacgcg atcgaggcca      1080
     cttgccacgc tccaaagctg gaaggtgtat acggtgagat ctacaaggtg ctgaagccag      1140
     gtggtacttt cgccgtttac gaatgggtca tgaccgaaaa ctacgacgaa aacaatgaag      1200
     agcaccgtaa gatcgcttac gagatcgagc taggtgatgg tattccaaag atgttcaccg      1260
     tcgacgttgc caagcaagct ttgaagaacg tcggtttcga agtcgaagtt tctaaggatc      1320
     ttgctgacga ggatgacgaa atcccatggt actacccatt gaccggtgaa tggaagtacg      1380
     ttcaatctct atccgatatc gctactttct tcagaacctc ttacttcggt agaaaattca      1440
     ctaactgtat ggtctccata atggaaaagg ttggtgtcgc cccacaaggt tccgttgaag      1500
     ttaccgctgc cctagaaaat gccgctgttg gtttggtcga aggtggtaga aagaaacttt      1560
     tcaccccaat gttcctattc gtcgctaaga agccagaaga tgctaaataa acaactgcag      1620
     cataactata ttcacacttt atgatgttac tttatttcca aacgattgtc tttaattaat      1680
     tttattcttg gccttatgag tgttacctgt cgtaatgcta atgaaattaa cgctaattat      1740
     gatttttgca aaattaaatt atagaagaga tctttagaat gttcacttga attcattcca      1800
     catg                                                                   1804
//