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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   AY827084; SV 1; linear; mRNA; STD; MAM; 738 BP.
XX
AC   AY827084;
XX
DT   24-OCT-2005 (Rel. 85, Created)
DT   24-OCT-2005 (Rel. 85, Last updated, Version 1)
XX
DE   Oryctolagus cuniculus thiopurine S-methyltransferase mRNA, complete cds.
XX
KW   .
XX
OS   Oryctolagus cuniculus (rabbit)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
XX
RN   [1]
RP   1-738
RX   DOI; 10.1097/01.fpc.0000174788.69991.6b
RX   PUBMED; 16220112.
RA   Salavaggione O.E., Wang L., Wiepert M., Yee V.C., Weinshilboum R.M.;
RT   "Thiopurine S-methyltransferase pharmacogenetics: variant allele functional
RT   and comparative genomics";
RL   Pharmacogenet. Genomics 15(11):801-815(2005).
XX
RN   [2]
RP   1-738
RA   Salavaggione O.E., Wiepert M., Yee V.C., Wang L., Weinshilboum R.M.;
RT   ;
RL   Submitted (15-NOV-2004) to the EMBL/GenBank/DDBJ databases.
RL   Molecular Pharmacology and Experimental Therapeutics, Mayo Foundation, 200
RL   First St. SW, Rochester, MN 55905, USA
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..738
FT                   /organism="Oryctolagus cuniculus"
FT                   /mol_type="mRNA"
FT                   /db_xref="taxon:9986"
FT   CDS             1..738
FT                   /codon_start=1
FT                   /product="thiopurine S-methyltransferase"
FT                   /note="TPMT"
FT                   /db_xref="GOA:Q3BCQ8"
FT                   /db_xref="InterPro:IPR016822"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q3BCQ8"
FT                   /protein_id="AAX37648.1"
FT                   /translation="MDDARTLLDIKEYPDTEVQKNRVLTLEEWQDKWVSHKIGFHQEQG
FT                   HKLLKKHLDAFLKGESGLRVFFPLCGKAVEMKWFADRGHSVVGVEISELGIREFFSEQN
FT                   LSYSEEPITEVPGAKVFKSSAGNISLYCCSIFDLPRVNIGKFDRIWDRGALVAVNPSDR
FT                   KRYAAVMLSLLRKGFQYLLAVLSYDPTKHAGPPFYVPDAEIKMLFDTKCKIHCLEKVDA
FT                   FEERHKSWGIDYIFEKLYLLTEK"
XX
SQ   Sequence 738 BP; 229 A; 130 C; 178 G; 201 T; 0 other;
     atggatgacg caaggacttt acttgatatt aaagagtacc ctgataccga ggtacaaaaa        60
     aaccgagtac taactctaga agaatggcaa gacaagtggg tgagccacaa aattggcttt       120
     catcaagagc aaggacacaa gctactaaag aaacatctgg acgcttttct gaaaggcgag       180
     agtggactga gggtgttttt tcctctttgt ggaaaagcag tcgagatgaa atggtttgca       240
     gaccgaggac acagtgtagt tggtgtagaa atcagtgaac ttgggatacg ggaatttttc       300
     tcggagcaga atctttctta ctcagaagaa ccgatcactg aagttcctgg agccaaagtc       360
     tttaagagtt ctgcggggaa tatctcattg tactgttgca gcatttttga tcttcccaga       420
     gtaaatatcg gaaaatttga cagaatttgg gatagaggag cattagtggc tgttaatcca       480
     agcgatcgaa aacgctatgc agctgtcatg ttgtccctgc tgaggaaggg gttccagtac       540
     ctcctggctg tgctttctta cgatccaact aaacatgcag gcccaccatt ttatgttcct       600
     gatgccgaaa ttaaaatgtt gtttgataca aaatgcaaga ttcattgtct tgagaaggtt       660
     gatgcatttg aagagcgaca taaaagttgg ggaattgact acattttcga aaagctatat       720
     ctactaactg aaaagtaa                                                     738
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