spacer
spacer
EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   AY827076; SV 1; linear; mRNA; STD; MAM; 738 BP.
XX
AC   AY827076;
XX
DT   24-OCT-2005 (Rel. 85, Created)
DT   24-OCT-2005 (Rel. 85, Last updated, Version 1)
XX
DE   Equus caballus thiopurine S-methyltransferase mRNA, complete cds.
XX
KW   .
XX
OS   Equus caballus (horse)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
XX
RN   [1]
RP   1-738
RX   DOI; 10.1097/01.fpc.0000174788.69991.6b
RX   PUBMED; 16220112.
RA   Salavaggione O.E., Wang L., Wiepert M., Yee V.C., Weinshilboum R.M.;
RT   "Thiopurine S-methyltransferase pharmacogenetics: variant allele functional
RT   and comparative genomics";
RL   Pharmacogenet. Genomics 15(11):801-815(2005).
XX
RN   [2]
RP   1-738
RA   Salavaggione O.E., Wiepert M., Yee V.C., Wang L., Weinshilboum R.M.;
RT   ;
RL   Submitted (15-NOV-2004) to the EMBL/GenBank/DDBJ databases.
RL   Molecular Pharmacology and Experimental Therapeutics, Mayo Foundation, 200
RL   First St. SW, Rochester, MN 55905, USA
XX
DR   Ensembl-Gn; ENSECAG00000013653; Equus_caballus.
DR   Ensembl-Tr; ENSECAT00000014717; Equus_caballus.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..738
FT                   /organism="Equus caballus"
FT                   /mol_type="mRNA"
FT                   /db_xref="taxon:9796"
FT   CDS             1..738
FT                   /codon_start=1
FT                   /product="thiopurine S-methyltransferase"
FT                   /note="TPMT"
FT                   /db_xref="GOA:Q3BCR6"
FT                   /db_xref="InterPro:IPR008854"
FT                   /db_xref="InterPro:IPR016822"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q3BCR6"
FT                   /protein_id="AAX37640.1"
FT                   /translation="MDGTRTVLDIKEYSDSEVQKNRVLTLEEWQGKWVTGKTIFHQEQG
FT                   HQLLKKHLDAFLKGESGLKVFFPLCGKAVEMKWFADRGHSVVGVEISELGIREFFTEQN
FT                   LSYSEEPIIEIPGAKVFKSSSGNISLYCCNIFDLPRTNIGKFDRIWDRGALVAVNPGDR
FT                   KRYVDIMLSLTRKGFHYLLAVLSYDPTKHAGPPFFVSDAEVKRLFDSVCNIRCLEKVDA
FT                   LEERHKSWGIDYLVETLYLFTEK"
XX
SQ   Sequence 738 BP; 228 A; 117 C; 178 G; 215 T; 0 other;
     atggatggga cgagaactgt acttgatatt aaagagtact ctgatagtga ggtacagaaa        60
     aaccgagtac taactctgga agaatggcaa ggaaaatggg tgaccggcaa aactatattt       120
     catcaagaac aaggacatca gctattaaag aagcatttgg atgcttttct taaaggcgag       180
     agtggactga aggtgttttt tcctctttgt ggaaaagcag ttgagatgaa atggtttgca       240
     gaccgaggac acagtgtggt tggcgtggaa atcagtgaac ttgggatacg ggaatttttc       300
     acagagcaga atctttctta ttcagaagaa cccatcatag aaattcctgg agccaaagta       360
     ttcaagagtt cttcagggaa catttcgttg tactgttgca acatttttga tcttcccaga       420
     acaaatattg gcaaatttga caggatttgg gatagaggag cattagtcgc tgtgaatcca       480
     ggtgatcgca aacgctatgt ggatataatg ctgtccctga ctagaaaagg gtttcactac       540
     cttttggctg ttctttctta tgacccaact aaacatgcag gcccgccatt ttttgtttcg       600
     gatgctgaag ttaaaagact atttgattca gtgtgcaata ttcgttgtct agagaaagtt       660
     gatgctttgg aagaacgcca taaaagttgg ggaattgact acttggttga aacgttatat       720
     ctatttacag aaaagtaa                                                     738
//
spacer
spacer