spacer
spacer
EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   AY819776; SV 1; linear; mRNA; STD; MAM; 738 BP.
XX
AC   AY819776;
XX
DT   24-OCT-2005 (Rel. 85, Created)
DT   24-OCT-2005 (Rel. 85, Last updated, Version 1)
XX
DE   Lynx rufus thiopurine S-methyltransferase mRNA, complete cds.
XX
KW   .
XX
OS   Lynx rufus (bobcat)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Lynx.
XX
RN   [1]
RP   1-738
RX   DOI; 10.1097/01.fpc.0000174788.69991.6b
RX   PUBMED; 16220112.
RA   Salavaggione O.E., Wang L., Wiepert M., Yee V.C., Weinshilboum R.M.;
RT   "Thiopurine S-methyltransferase pharmacogenetics: variant allele functional
RT   and comparative genomics";
RL   Pharmacogenet. Genomics 15(11):801-815(2005).
XX
RN   [2]
RP   1-738
RA   Salavaggione O.E., Wiepert M., Yee V.C., Wang L., Weinshilboum R.M.;
RT   ;
RL   Submitted (05-NOV-2004) to the EMBL/GenBank/DDBJ databases.
RL   Molecular Pharmacology and Experimental Therapeutics, Mayo Foundation, 200
RL   First St. SW, Rochester, MN 55905, USA
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..738
FT                   /organism="Lynx rufus"
FT                   /mol_type="mRNA"
FT                   /db_xref="taxon:61384"
FT   CDS             1..738
FT                   /codon_start=1
FT                   /product="thiopurine S-methyltransferase"
FT                   /note="TPMT"
FT                   /db_xref="GOA:Q3BCR9"
FT                   /db_xref="InterPro:IPR008854"
FT                   /db_xref="InterPro:IPR016822"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q3BCR9"
FT                   /protein_id="AAX37638.1"
FT                   /translation="MDDTSTLIDVKEYPDTEVQKNRVLTLEEWREKWVDGKIGFHQEQG
FT                   HQLLKKHLDTFLKGENVLRVFFPLCGKAVEMKWFADRGHCVVGVEISELGIREFFTEQN
FT                   LSYSEEPIMEIPGAKVFKSSSGNISLYCCNLFDLPRVNIGKFDRIWDRGALVAVNPGDR
FT                   KCYTDIMLSLTRKGFRYLLAVLSYDPTKHPGPPFYVPDAEIKNLFGSTCNIHCLEKVDV
FT                   FEERHKSWGIDYIVEKLYLLTEK"
XX
SQ   Sequence 738 BP; 225 A; 127 C; 174 G; 212 T; 0 other;
     atggatgata caagcacttt aattgatgtt aaagagtacc ccgataccga ggtacagaaa        60
     aaccgagtac taactctgga agaatggcga gaaaagtggg tggacggcaa aattggattt       120
     catcaagaac aaggacatca attattaaag aagcatttgg atactttcct taaaggcgag       180
     aatgttctga gagtattttt tcctctttgt ggaaaagcag ttgagatgaa atggtttgcg       240
     gaccgaggac actgtgtagt gggtgtggaa atcagtgagc ttgggattcg ggaatttttt       300
     acagagcaga atctttctta ctcggaagag cccatcatgg aaattcctgg agccaaagta       360
     ttcaagagtt cttcagggaa catttcactg tactgttgca acctttttga tcttcccaga       420
     gtgaacattg gcaaattcga caggatctgg gatagaggag cattagttgc tgttaaccca       480
     ggcgatcgta aatgctatac agacataatg ctgtccctaa cgaggaaagg gtttcgctac       540
     ctcttggctg ttctttctta tgatcccact aaacatccag gcccaccgtt ttatgttcca       600
     gatgctgaaa ttaaaaactt gtttggttca acatgcaaca ttcattgcct tgagaaggtt       660
     gatgtttttg aagaacgaca taaaagttgg ggaattgact acattgttga aaagttgtat       720
     ctacttacgg aaaagtaa                                                     738
//
spacer
spacer