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EBI DbfetchID AY786508; SV 1; linear; mRNA; STD; VRT; 3195 BP. XX AC AY786508; XX DT 07-NOV-2004 (Rel. 81, Created) DT 21-OCT-2008 (Rel. 97, Last updated, Version 3) XX DE Danio rerio exostosin-2 (ext2) mRNA, complete cds. XX KW . XX OS Danio rerio (zebrafish) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. XX RN [1] RP 1-3195 RX DOI; 10.1016/j.neuron.2004.11.029 RX PUBMED; 15603738. RA Lee J.-S., von der Hardt S., Rusch M.A., Stringer S.E., Stickney H.L., RA Talbot W.S., Geisler R., Nuesslein-Volhard C., Selleck S.B., Chien C.-B., RA Roehl H.H.; RT "Axon sorting in the optic tract requires HSPG synthesis by ext2 (dackel) RT and extl3 (boxer)"; RL Neuron 44(6):947-960(2004). XX RN [2] RP 1-3195 RA Lee J.-S., von der Hardt S., Chien C.-B., Roehl H.H.; RT ; RL Submitted (18-OCT-2004) to the EMBL/GenBank/DDBJ databases. RL Department of Biomedical Science, University of Sheffield, Firth Court, RL Western Bank Dept of Biomedical Sciences, Sheffield S10 2TN, United Kingdom XX DR Ensembl-Gn; ENSDARG00000004814; Danio_rerio. DR Ensembl-Gn; ENSDARG00000018716; Danio_rerio. DR Ensembl-Gn; ENSDARG00000033533; Danio_rerio. DR Ensembl-Gn; ENSDARG00000035694; Danio_rerio. DR Ensembl-Gn; ENSDARG00000056648; Danio_rerio. DR Ensembl-Gn; ENSDARG00000062667; Danio_rerio. DR Ensembl-Gn; ENSDARG00000069382; Danio_rerio. DR Ensembl-Gn; ENSDARG00000078855; Danio_rerio. DR Ensembl-Tr; ENSDART00000013111; Danio_rerio. DR Ensembl-Tr; ENSDART00000014496; Danio_rerio. DR Ensembl-Tr; ENSDART00000026174; Danio_rerio. DR Ensembl-Tr; ENSDART00000047015; Danio_rerio. DR Ensembl-Tr; ENSDART00000051768; Danio_rerio. DR Ensembl-Tr; ENSDART00000074620; Danio_rerio. DR Ensembl-Tr; ENSDART00000079165; Danio_rerio. DR Ensembl-Tr; ENSDART00000090861; Danio_rerio. DR Ensembl-Tr; ENSDART00000100922; Danio_rerio. DR Ensembl-Tr; ENSDART00000100925; Danio_rerio. DR Ensembl-Tr; ENSDART00000102024; Danio_rerio. DR Ensembl-Tr; ENSDART00000105174; Danio_rerio. DR Ensembl-Tr; ENSDART00000109648; Danio_rerio. DR Ensembl-Tr; ENSDART00000110763; Danio_rerio. XX FH Key Location/Qualifiers FH FT source 1..3195 FT /organism="Danio rerio" FT /chromosome="LG 7" FT /mol_type="mRNA" FT /clone="Tuebingen" FT /note="dackel mutant embryos" FT /db_xref="taxon:7955" FT gene 1..3195 FT /gene="ext2" FT CDS 193..2352 FT /codon_start=1 FT /gene="ext2" FT /product="exostosin-2" FT /note="HSPG co-polymerase; glycosyltransferase; Golgi FT enzyme required during the synthesis of heparan sulfate FT proteoglycans" FT /db_xref="GOA:Q5U7A7" FT /db_xref="InterPro:IPR004263" FT /db_xref="InterPro:IPR015338" FT /db_xref="UniProtKB/TrEMBL:Q5U7A7" FT /db_xref="ZFIN:ZDB-GENE-041124-3" FT /protein_id="AAV48783.1" FT /translation="MCASGKYGSRGPALIPRMKTKHRIYYITLFSVVLLGLIATGMFQF FT WPHSIESSAEWSLDRRSVHDAPLVRISVNSPIPGRGDLSCRMHTCFDVYRCGYNPKNKI FT KVYIYPLQRFVDEVGVPISSTGLSREYNDLLSAISDSDFYTDDVSRACLFVPSIDVLNQ FT NSLRIRETAQALAMLPRWDKGMNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWT FT YRQGYDVSIPVYSPLSAEVDLPERQPGPRRYFILSSQTAIHREYRVELERLKDENGEAL FT LLLDKCSNLSQGLTSVRKRCYKGQVYDYPQILQESSFCVVLRGARLGQATLSDVLQAGC FT VPVIMADSYILPFSEVLDWKRASVVIPEEKLPEMYTILKSIPHRQVEEMQRQARWFWEA FT YFSSMKAIGMTTLQIINDRIYPYAAHTYEEWNNPPVVKWSSVNSPLFLPLIPPRSPGFT FT AVVLTYDRIESLFRVITEISKVPSLAKLLVVWNNQNKSPPEESLWPKVAVPLKVVRTKE FT NKLSNRFFPFDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDH FT EMGKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFL FT VANITGKAPIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVE FT HRADPVLYKDDFPEKLKSFPNIGSL" XX SQ Sequence 3195 BP; 829 A; 689 C; 742 G; 931 T; 4 other; cgacccacgc gtccgctctt ctttcctgtc agctgtcctt ttagtgtaag gaatgtgttg 60 tgggatgata aataacattc aacttaaata ttcaccatac tggaacgaca aatgaaataa 120 tgtttgcggc gtgctgaagt ttgaggccgt aagctggaca tcgtgaagtg gttttgtctg 180 gacaggctca tcatgtgtgc atcagggaag tacggttcac ggggccctgc tctcataccc 240 cgcatgaaga ctaaacaccg gatctactac atcaccctct tctctgtggt cttgctggga 300 ttgatcgcaa cagggatgtt ccagttctgg cctcactcca ttgagtcttc agctgaatgg 360 agtctggacc gccgcagtgt gcacgatgct cctttggtca ggatttctgt gaacagtcct 420 attcctggga ggggtgacct gagctgccgg atgcacacct gctttgatgt ttatcgctgt 480 ggatataatc ctaagaacaa aatcaaggtg tacatctatc cacttcagag gtttgtggat 540 gaagtaggag tgcccatcag tagcactggc ctgtctcgag aatacaatga cctgctgagc 600 gccatctcgg acagtgactt ctacactgat gatgtgtcca gagcgtgtct gtttgtacct 660 tctattgatg tactgaatca gaactctctg cgtattcgag aaactgctca ggcactggcc 720 atgctgccya ggtgggacaa aggcatgaac cacctgctgt ttaayatgct tcctggagga 780 cctcctgact acaatacagc tctggatgtg ccgagagaca gagccctgct ggctggggga 840 ggcttctcca catggaccta cagacaaggt tatgatgtca gcatacctgt gtatagccct 900 ttatctgctg aggtggacct tcctgagagg caacccggtc ctcggcgcta cttcattctg 960 tcatctcaga cagccattca tagggaatac cgtgtggaac tggaaaggct gaaggatgag 1020 aatggggagg ccctgctcct gttagacaaa tgcagtaatc tctctcaggg tttgacctcg 1080 gttagaaagc gctgctataa aggacaggtg tacgactacc cacaaatttt acaggagtcg 1140 tcattctgtg tggttctgcg tggggctcga ttaggccaag ccacgctcag tgacgtgctg 1200 caagcgggat gtgtccctgt catcatggct gattcttata ttctgccttt ctctgaagtg 1260 ctggactgga aaagggcgtc tgttgtcatt ccagaagaaa agttgccaga gatgtacacc 1320 attttgaaga gcatacctca cagacaagtg gaggagatgc agagacaggc tcgctggttt 1380 tgggaagcct acttcagctc catgaaggct attggcatga cgactctcca gatcattaat 1440 gatcgcattt acccwtatgc agctcatacc tatgaagaat ggaacaatcc tcctgtggtt 1500 aaatggtcga gtgtgaacag tccacttttc cttcctctca taccgccacg ctctcctggg 1560 ttcacagctg tcgtgttgac ttatgatcgt attgaaagcc tttttagggt catcactgag 1620 atctccaagg tgcccagttt ggccaaacta ctggtggtgt ggaacaacca gaacaaaagc 1680 ccacctgaag agtcgctgtg gcccaaagtc gcagtgcctc ttaaagtggt ccgcaccaaa 1740 gaaaacaagc tcagcaatcg cttctttccg tttgatgaga tcgagacaga agctgtcctg 1800 gccattgacg atgacatcat catgttaacc tcagatgagc tacagtttgg atatgaggta 1860 tggcgtgagt tccctgacag gctggttgga tatcctggtc ggctccattt atgggatcat 1920 gaaatgggca aatggaaata cgaatctgaa tggactaatg aagtatccat ggtcttgact 1980 ggtgctgctt tctaccataa gtatttcaac tatctctaca cctataaaat gcctggagac 2040 atcaagaact gggtggatgc tcacatgaac tgtgaagata ttgctatgaa cttccttgtg 2100 gccaacatca ctggaaaagc accaataaag gttactcctc ggaagaaatt taaatgcccg 2160 gagtgcacag caattgatgg gttgtccttg gaccagacac acatggtgga gaggtctgag 2220 tgcataaaca agttcgcctc tgtgttcggc accatgcctc tgaaggttgt cgagcaccgt 2280 gctgatcctg tactctacaa agacgacttc ccagagaaac tcaaaagttt ccccaacatt 2340 ggcagtctgt gacactacca cagcgactct ttcccaccac ttattttttt ttctctcaga 2400 caggctacgg gcactccggg atttctcttt atgttcctta tctgacctaa tgactctgga 2460 ggagtgttgt tccactgttt tgtgatggga actcacacac tgtataactt attatgtttt 2520 cactcttgag gacagttgct gaaacaacag ttgcgacgca tcaaagcagt ggatgatttc 2580 tatgaggact ggtcacaagc cgaaaccttc cttgtggccg acgcctgtgt atctgtgtga 2640 gaaaagtgaa cactctgagg tgtatcacaa tccactggta aacagtggag actatgtatt 2700 aatgtaattt tacatttaac ttttttattt taaagatatg catcatgctg aacaaattgt 2760 agcataactt gaactgaata tctgggatgt cggaattagt ttgtacatga gatattgttt 2820 tgcacagtca ctgattttaa tattacactt tgagtgctat cagtttgaca tttcatttta 2880 tattcagttg ctgacttttt gaatgttgct ggagaaaaga aaaagtattt tatataaatg 2940 ttcgctatta tgtctttcct ttgttaaagc atatttgcgt attaatagat attaaaatac 3000 actatttgca gaattatatg ctgtacagct gatacggtta tatagcgcaa gatttcaaag 3060 attattagtc tcatttcggt ttctcagttt cctcctttga tttgtttttt gtttgtttgt 3120 ttttttttat agtaagatgt attatatgta ataaacagtg agtgtgtaac mctaaaaaaa 3180 aaaaaaaaaa aaaaa 3195 // |
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