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EBI DbfetchID AY705915; SV 1; linear; genomic DNA; STD; PRO; 11392 BP. XX AC AY705915; XX DT 27-FEB-2006 (Rel. 86, Created) DT 27-FEB-2006 (Rel. 86, Last updated, Version 1) XX DE Lactobacillus rhamnosus lacTEGF and galKETRM operons, complete sequence. XX KW . XX OS Lactobacillus rhamnosus OC Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus. XX RN [1] RP 1-11392 RX DOI; 10.1111/j.1365-2672.2005.02790.x RX PUBMED; 16478484. RA Tsai Y.K., Lin T.H.; RT "Sequence, organization, transcription and regulation of lactose and RT galactose operons in Lactobacillus rhamnosus TCELL-1"; RL J. Appl. Microbiol. 100(3):446-459(2006). XX RN [2] RP 1-11392 RA Tsai Y.K., Lin T.H.; RT ; RL Submitted (05-AUG-2004) to the EMBL/GenBank/DDBJ databases. RL Life Science, National Tsing Hua University, 101, Section 2 Kuang Fu Road, RL Hsinchu, Taiwan 300, Republic of China XX FH Key Location/Qualifiers FH FT source 1..11392 FT /organism="Lactobacillus rhamnosus" FT /strain="TCELL-1" FT /mol_type="genomic DNA" FT /db_xref="taxon:47715" FT misc_feature 287..321 FT /note="similar to the ribonucleic antiterminator(RAT) FT sequences of the BglG family of transcriptional FT antiterminators" FT stem_loop 316..356 FT /note="rho-independent terminator" FT operon 376..5268 FT /operon="lacTEGF" FT gene 376..1266 FT /operon="lacTEGF" FT /gene="lacT" FT RBS 376..380 FT /gene="lacT" FT CDS 388..1266 FT /codon_start=1 FT /transl_table=11 FT /operon="lacTEGF" FT /gene="lacT" FT /product="LacT" FT /note="antiterminator protein" FT /db_xref="GOA:Q29ZJ3" FT /db_xref="InterPro:IPR011608" FT /db_xref="UniProtKB/TrEMBL:Q29ZJ3" FT /protein_id="AAW30153.1" FT /translation="MPKIDQIFNNNVALVELDNHSQAVVKGRGIAFQKKRGDVIPAKQI FT EKIFYLASETSRQNLYFLLRNIPIDVVTTTYEIIDVAQKQFHLKVLDYIYITLSDHIYE FT AYKRYQNGTYQETMVPDFHIQYPAEYAVANQALQIIAANLGVAFPPSEVKNLALHFINA FT SGEDDNEQAFDKNNEASLSQLVQRVLKRHRITRSQTNGNYYDRFMIHLQYLIDRLQRVN FT TDAVAIVPEVANELEQNYPRSYQIASEIFDEIKDQLYRNMSEDERLYFIIHIQRLINEA FT PAHDQKQGKKS" FT gene 1303..3028 FT /operon="lacTEGF" FT /gene="lacE" FT RBS 1303..1307 FT /gene="lacE" FT CDS 1316..3028 FT /codon_start=1 FT /transl_table=11 FT /operon="lacTEGF" FT /gene="lacE" FT /product="LacE" FT /note="EIIBC lactose PTS" FT /db_xref="GOA:Q29ZJ2" FT /db_xref="InterPro:IPR014350" FT /db_xref="UniProtKB/TrEMBL:Q29ZJ2" FT /protein_id="AAW30154.1" FT /translation="MNKVFDKLKPIFEAIAANKYVSAIRDGFIACMPIIIFSSIFMMIA FT YVPNAWGFYWPKNVTDTLMIAYNYSMGLLALFVAGTTAKNLTDSKNLELPKTNQINPVA FT VIVASEIAFVILSILPLKTGVDLTYMGTQGLICAYIVGLIVPNIYYVCIKNNVTIKLPP FT QVPGNISQSFKDLIPMGLSVSAFWLFGVGFKAATGTILPRWIIQVLSPLFQASDSYLGL FT ALIAGAMAFFWFCGVQGPSIVQPAVVPIMIANTAANLQQYQAGQHVSHVLAMNTMDYVM FT NFGGTGSTLVVAFVMLFAARSAQLKAVGKAAFIPGTFSVNEPVLFGMPIIMNPMFFIPF FT LATPIVNVCLFKFFVSVLGMNSMIYTMPWTVPAPIGILVSTGFAPLAFVFVLLTLVLDV FT LIYFPFIRVYDRTLLAEEKAKEDVIEGQDTAVLAADTVAPQTAEVQVEASEMADEKPAA FT AHDESFFKNNEIDVLVLCAGGGTSGILANALNKLSKERGLKLSAAARAYGQDMDLIKDM FT SMVILAPQMESMKDNLKKITDKYGVKLVTTTGRQYIELTNNGDMALDFVESNL" FT gene 3069..4508 FT /operon="lacTEGF" FT /gene="lacG" FT RBS 3069..3073 FT /gene="lacG" FT CDS 3084..4508 FT /codon_start=1 FT /transl_table=11 FT /operon="lacTEGF" FT /gene="lacG" FT /product="LacG" FT /note="phospho-beta-galactosidase" FT /db_xref="GOA:Q29ZJ1" FT /db_xref="InterPro:IPR005928" FT /db_xref="UniProtKB/Swiss-Prot:Q29ZJ1" FT /protein_id="AAW30155.1" FT /translation="MRKQLPKDFVIGGATAAYQVEGATKEDGKGRVLWDDFLEKQGRFS FT PDPAADFYHRYDEDLALAEAYGHQVIRLSIAWSRIFPDGAGAVEPRGVAFYHRLFAACA FT KHHLIPFVTLHHFDTPERLHAIGDWLSQEMLEDFVEYARFCFEEFPEIKHWITINEPTS FT MAVQQYTSGTFPPAETGHFDKTFQAEHNQIVAHARIVNLYKSMGLDGEIGIVHALQTPY FT PYSDSSEDQHAADLQDALENRLYLDGTLAGDYAPKTLALIKEILAANQQPMFKYTDEEM FT AAIKKAAHQLDFVGVNNYFSKWLRAYHGKSETIHNGDGSKGSSVARLHGIGEEKKPAGI FT ETTDWDWSIYPRGMYDMLMRIHQDYPLVPAIYVTENGIGLKESLPAEVTPNTVIADPKR FT IDYLKKYLSAVADAIQAGANVKGYFVWSLQDQFSWTNGYSKRYGLFFVDFPTQKRYVKQ FT SAEWLKQVSQTHVIPE" FT gene 4785..5132 FT /operon="lacTEGF" FT /gene="lacF" FT RBS 4785..4789 FT /gene="lacF" FT CDS 4797..5132 FT /codon_start=1 FT /transl_table=11 FT /operon="lacTEGF" FT /gene="lacF" FT /product="LacF" FT /note="EIIA lactose PTS" FT /db_xref="GOA:Q29ZJ0" FT /db_xref="InterPro:IPR003188" FT /db_xref="UniProtKB/TrEMBL:Q29ZJ0" FT /protein_id="AAW30156.1" FT /translation="MATREEISMVGFALVAYAGDARTAALRALNAAEAGDFEGAEAKLD FT EAQKDINEAHNQQTQLLSQEAGGAEMDVTFIMVHGQDTLMTTMLLIDQSRYMIRMLKRI FT KQLEDKQ" FT stem_loop 5227..5268 FT /operon="lacTEGF" FT /note="rho-independent terminator" FT operon 5454..11319 FT /operon="galKETRM" FT gene 5454..6633 FT /operon="galKETRM" FT /gene="galK" FT RBS 5454..5458 FT /gene="galK" FT CDS 5467..6633 FT /codon_start=1 FT /transl_table=11 FT /operon="galKETRM" FT /gene="galK" FT /product="GalK" FT /note="galactokinase" FT /db_xref="GOA:Q29ZI9" FT /db_xref="InterPro:IPR019539" FT /db_xref="UniProtKB/TrEMBL:Q29ZI9" FT /protein_id="AAW30157.1" FT /translation="MNSTDVTKGFTEQFGKQAEHTFFAPGRINLIGEHTDYNGGHVFPC FT AISLGTYAAVGANDDNAFRLYSANFPKVGIIDIPFPDLFQDKRGLWTDYFQGMARVMKT FT AGINYTHGLNVYINGNLPDGAGLSSSASLEMLVGTILNNLFDGGFAPLDLVKFGVKVEN FT DYIGVNSGIMDQFAIEMGRANQATLLDTNTMKYEYLPVEMGDNVIVIMNTNKRRELTDS FT KYNERRSECEKALAMLQKGIDVKSLGQLTEDEFDENTYLIYDETLIKRARHAVFENQRT FT LTAAKALQSGDLKTFGKLVSASGVSLAFDYEVTGIELDTLVTNALKQRGVLGARMTGAG FT FGGCAIAIVNSADVEDFISNVGKAYTEKIGYDAHFYVADIADGAKQLN" FT gene 6685..7695 FT /operon="galKETRM" FT /gene="galE" FT RBS 6685..6689 FT /gene="galE" FT CDS 6700..7695 FT /codon_start=1 FT /transl_table=11 FT /operon="galKETRM" FT /gene="galE" FT /product="GalE" FT /note="UDP-galactose 4-epimerase" FT /db_xref="GOA:Q29ZI8" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q29ZI8" FT /protein_id="AAW30158.1" FT /translation="MTIAVLGGAGYIGSHTVKQLLADGEDVIVLDNLITGHRKAVDPRA FT RFYQGDIRDYHFLSQVFSQEKIDGIVHFAAFSIVPESMKDPLKYFDNNTGGMITLLEAM FT NQFGIKKIVFSSTAATYGEPKQVPIKETDPQVPTNPYGESKLAMEKIMHWADVAYGLKY FT VALRYFNVAGAMTDGSIGEDHHPETHLIPIILQVAAGSRTGLQIYGDDYPTKDGTNVRD FT YVHVVDLADAHVLAVKYLNAGNPSSAFNIGSAHGFSNMEILNAARKVTGQKIPATVGPR FT RPGDPSTLVASSEKARDILGWKPNYDDIDKIIETAWNWHENHPEGFGDRN" FT gene 7681..9149 FT /operon="galKETRM" FT /gene="galT" FT RBS 7681..7685 FT /gene="galT" FT CDS 7692..9149 FT /codon_start=1 FT /transl_table=11 FT /operon="galKETRM" FT /gene="galT" FT /product="GalT" FT /note="galactose 1-phosphate-uridyltransferase" FT /db_xref="GOA:Q29ZI7" FT /db_xref="InterPro:IPR005850" FT /db_xref="UniProtKB/TrEMBL:Q29ZI7" FT /protein_id="AAW30159.1" FT /translation="MTAISNHIETIIKPNPDYTQMDPVYLTNKLLNLIGDAALELPGDP FT DPLDNLDLMVKAAQTNGKIADSQAARQILEAQLMDFATPTPSRINQLFWDKYQAGPRAA FT TDWFFALSRANNYIQTRAIAKNLVFPAKTEYGDLEITINLSKPEKDPKDIAAAAHAQSG FT YPACALCLQTEGYAGRSNFAARTNHRIIRFLLGGKTWGFQYSPYAYFNEHAIFLDAIHE FT PMVIDQSTFTNLLDIVAMFPDYFVGSNADLPIVGGSMLAHEHYQGGRHTFPMAKAPIET FT QIEISGHPHVFAGIVKWPMSVIRLVSADREELTNAAEHIRQVWNQYTDEAVNVRAFVEG FT KPHHTVTPIARRVGSEYQLDLVLRDNQTSEQYPDGIFHPHQDVQHIKKENIGLIEVMGR FT AILPARLKSELAEVKKYLLGEANEMKPMHKTWADQLKVAYNWTPENAESQLQEAVGKVF FT ARVLEDAGVFKRDKIGQEAFGRFCHSL" FT gene 9180..10186 FT /operon="galKETRM" FT /gene="galR" FT RBS 9180..9184 FT /gene="galR" FT CDS 9191..10186 FT /codon_start=1 FT /transl_table=11 FT /operon="galKETRM" FT /gene="galR" FT /product="GalR" FT /note="putative repressor protein of the gal-operon" FT /db_xref="GOA:Q29ZI6" FT /db_xref="InterPro:IPR001761" FT /db_xref="UniProtKB/TrEMBL:Q29ZI6" FT /protein_id="AAW30160.1" FT /translation="MTTITDIAKAAGVSIATVSRILNYDATLAVTPETRQRVLKTAEKL FT AYKPRRRKRVATQTTVALIQWRSEQEELNDLYYLQIQYAIEARAASIGYHVQNLHLEQL FT NAESVANVQGIIALGKYDAGEVAEIKALGLPIVFVDQNMLAFDCDSVTGDYAGPIAQII FT DHFQKVGIDDIGFLGGLETSRSGREQFQDVRTATFDRVTKAAGIDHAEFRLIGEFTPDS FT GYRLMRQAIEKLGERLPHAFIIANDTMAVGALRALNEANISVPQRVSVISFNDVAVAKF FT TTPPLSTVHAATDQMGQTAVELLQARLNDAKRVPRQVNFKSELIMRASSL" FT gene 10251..11271 FT /operon="galKETRM" FT /gene="galM" FT RBS 10251..10255 FT /gene="galM" FT CDS 10258..11271 FT /codon_start=1 FT /transl_table=11 FT /operon="galKETRM" FT /gene="galM" FT /product="GalM" FT /note="mutarotase" FT /db_xref="GOA:Q29ZI5" FT /db_xref="InterPro:IPR015443" FT /db_xref="UniProtKB/TrEMBL:Q29ZI5" FT /protein_id="AAW30161.1" FT /translation="MMDVSVEQYGQYQGQNLYELTLTNDQGMVVKLLNYGATLEKVLLP FT EADGLHNMVLSLPTREDYSKERNFLGGTVGRIVGRIRGHVWQHGDVKVDLPMNEGKNHI FT HGGDDGLDRQVYNFRTEQTATTASASFTFVDPAGHNGYPGNLKLQVTYTLTNANALQYR FT VDALSDEETLFNPTTILIFALDHPATIDETVLTIPADAYKPLDAEHLPDQGWQPVAGTV FT LDFRNGQKLGDVIHTRADQITSERGINHPFLLKNGKALAAKLQTKNHTMTLVTTAPSVV FT VYTANHFDGTGVAHNIKQFDGVALECQYPPVSGSDLSAITLLPGEPFTLANTWTFE" FT stem_loop 11281..11319 FT /operon="galKETRM" FT /note="rho-independent terminator" XX SQ Sequence 11392 BP; 3033 A; 2367 C; 2920 G; 3072 T; 0 other; taacaggttg ctcattcgtc tcgatcatta tcgtctgatt taggaaggcg tcaattaaaa 60 tgcttggcgc ggatgggggg tacgattcag ccacaaaaat tgcgaggtga aaacagcagt 120 tacagtattg ttgttatttt atctatgaat gtgcttgtct atatggcaag tgaactttta 180 aaacgattat gcaaaaacgt ctgtgaaaat tcagaaagta aatcaaataa aacgtttaca 240 ttttgtttat atatggtaca atttgtttgt tgataggaat attcattgtg gattgtgact 300 attcaattag gcgagaccac aaatcatgac gctgagagta gcgcgtgatt tgtggttttt 360 tctatgtctg ggtgaggaga tgatgagatg ccgaaaatcg atcagatctt taacaataac 420 gtggcgttgg ttgagctaga caaccatagt caagcggttg ttaagggacg ggggatcgcg 480 tttcaaaaga agcgtggcga tgtgattccg gctaaacaaa ttgaaaaaat tttctacctt 540 gcaagtgaaa cttcccgcca gaatctgtac tttttacttc gcaatattcc gatcgacgtg 600 gtgacgacca cttatgaaat tattgacgtt gcgcaaaagc aatttcacct taaggtactt 660 gactatattt acattacgtt aagcgatcat atttacgaag cctataaacg ttatcagaat 720 ggaacgtatc aagagacgat ggtgccggat tttcatattc agtatcctgc agagtatgcc 780 gtagctaacc aagcgttgca gatcattgca gctaaccttg gcgtagcatt tccaccttcc 840 gaagtgaaaa atcttgcctt gcatttcatc aatgccagcg gtgaagacga caacgagcag 900 gcctttgata agaataatga ggcgtcatta agtcaactgg tgcaacgcgt tttgaagcgg 960 catcgcatta cgagatcgca aactaacggc aattattatg atcgcttcat gattcactta 1020 cagtatctga ttgaccgact gcagcgtgtt aatacggatg ctgttgccat tgtgcccgag 1080 gtggccaatg aattagagca aaattatccg cggtcttatc agattgcttc ggaaattttt 1140 gatgagatta aggatcagct ttatcgcaac atgagtgaag acgaacgctt atactttatc 1200 attcatattc agcggctaat taacgaagcg cctgcccacg atcaaaaaca gggcaaaaaa 1260 tcataacgcg tttgctggct tggagggcag catacgctca cgggaggaaa gtatcatgaa 1320 taaggttttc gataagctaa agccgatttt tgaagcgatt gcggcgaata agtatgtgtc 1380 cgcaatccgt gatggcttta ttgcctgtat gccgatcatc atcttctcca gtatcttcat 1440 gatgatcgct tatgttccta atgcttgggg gttttactgg cctaagaatg tgaccgatac 1500 cctgatgatt gcttacaact actcaatggg attgttggca ttatttgttg ccggtacgac 1560 tgcaaagaat ttaaccgaca gcaagaatct ggaattaccc aagacaaacc agatcaatcc 1620 ggttgcggtc attgttgctt cggaaatcgc ctttgtcatt ttatcgattt taccgcttaa 1680 aaccggggtc gatttaacct acatgggcac tcagggcttg atctgcgctt atatcgtcgg 1740 cttaattgtg cctaatattt actacgtttg tattaaaaac aacgtcacga ttaagttgcc 1800 gccacaggtt ccaggcaata tctcccagtc atttaaagat ttaattccaa tggggctatc 1860 tgttagtgct ttttggctct ttggcgttgg gtttaaagca gcaacgggaa cgatcctgcc 1920 gcgctggatt attcaagtgt tgtcgccact cttccaggcc agtgattctt atctggggtt 1980 agcgttgatt gccggcgcga tggcattctt ctggttctgt ggggttcagg ggccttcaat 2040 tgtccagccg gctgttgttc cgatcatgat tgccaataca gcggccaatc tccagcaata 2100 tcaagccgga cagcatgttt cacatgtgtt ggcgatgaac acgatggatt atgttatgaa 2160 ttttggcggt acgggatcga ctctggttgt cgcgttcgtg atgctgtttg cggcgcgttc 2220 ggcacaatta aaagcagtcg ggaaagcggc ttttatcccg ggaacatttt ctgttaacga 2280 gccggtactt ttcgggatgc cgattattat gaatccgatg tttttcattc cgtttttggc 2340 aacgccgatc gtgaatgttt gcctgtttaa gttctttgtc agtgtgttag gcatgaatag 2400 catgatctac accatgccgt ggacggtacc ggcacccatc gggatcttag tttcaaccgg 2460 ttttgctcca ctggcatttg tctttgtatt gttgacactt gtgttagacg tccttatcta 2520 cttcccgttt attcgcgtgt acgatcgaac gcttttagcc gaagaaaaag ctaaagaaga 2580 tgtgattgaa ggacaggata cggcggtttt ggctgccgat acggttgcac cacaaacggc 2640 tgaggttcag gtcgaagcat ccgaaatggc tgatgaaaaa ccagcggcag cgcatgatga 2700 gagtttcttc aaaaataatg aaattgacgt tctggtgctt tgtgccggtg gtggaaccag 2760 tggcatctta gccaatgcgc taaacaagct gtctaaggag cgggggttga agttgtccgc 2820 cgcggctcgg gcttatggac aggatatgga cttgatcaaa gatatgagta tggtcattct 2880 ggcgccacaa atggaaagta tgaaggataa tttgaaaaag attaccgata aatatggcgt 2940 taagttggtt acaaccactg gccgccagta cattgaactg acaaacaacg gcgatatggc 3000 actggatttt gttgagtcca atctttaggc gttcatcaac ctagacagac tcgtctgcat 3060 actttatagg aggaagttaa aacatgcgta aacaattacc caaggacttt gtaatcggtg 3120 gcgcaactgc tgcttaccaa gttgaagggg caaccaaaga agacggaaaa ggtcgagttc 3180 tttgggatga ttttctggaa aaacaagggc ggtttagtcc tgaccccgcc gctgattttt 3240 atcatcgcta tgatgaggat ttggcgttag cagaagcata tggtcatcaa gtaatacggc 3300 tttcaattgc ctggtcgcga atttttccgg atggtgccgg ggcggtggaa cctcgtggcg 3360 ttgctttcta tcatcggctc tttgctgcct gtgccaagca tcatcttatc ccgtttgtaa 3420 cgttgcatca ttttgataca ccagaacggt tacatgcgat tggtgactgg ctgagtcaag 3480 aaatgctgga agattttgtc gagtacgcgc ggttttgctt cgaagaattt ccggaaatca 3540 aacactggat tacgatcaat gaaccaacgt ccatggcagt gcaacaatat acgagcggta 3600 cttttccacc agcggaaacc ggtcattttg ataaaacatt tcaggccgaa cataatcaaa 3660 tcgttgccca tgcgcgtatt gttaatttgt acaagtcgat ggggctagat ggtgaaatcg 3720 gtatcgtgca tgccttgcag acaccttatc catatagtga ttcgtcggaa gatcagcatg 3780 ccgctgattt acaggatgcg ttggaaaatc gcctgtattt agatggcaca ctggcaggag 3840 attacgcccc taagaccttg gctttgatca aagaaattct ggcagccaat caacaaccga 3900 tgtttaagta cactgatgaa gagatggcgg ctattaagaa ggcggcgcac cagcttgatt 3960 ttgttggcgt taataattac ttcagcaaat ggctgcgcgc ttatcacggc aagtcggaaa 4020 cgattcataa tggtgatggc tcaaagggat cgtcagttgc ccgccttcac ggtatcggcg 4080 aggagaagaa gccagccggg attgagacaa cggattggga ctggtccatc tatccgcgtg 4140 gtatgtatga catgttgatg cggattcacc aagattatcc gttagtacca gccatctatg 4200 tcaccgaaaa cggtattgga ttgaaagaat ccttaccagc agaagtgacg ccaaatacgg 4260 tcatcgcgga tcccaaacgc attgattatt tgaaaaaata tttaagtgcc gttgcagatg 4320 caattcaggc tggtgcgaat gtaaaaggct actttgtttg gtcactgcag gatcagtttt 4380 cctggacaaa tggttatagc aaacggtacg gattgttttt cgtcgacttt ccgacgcaaa 4440 aacgttatgt caagcaaagt gccgaatggt taaaacaagt tagccaaacg catgtgattc 4500 cggaataagc gcgccggctc gcgctcatat taacgcgctc cccggcgcag gaatctgcgt 4560 gtaaggacct gggtcgcaat ggccaaagag cgggccattt cgcccgaggc cgcttacact 4620 ccgacttcta cccgcgccgg ctcgcgctca cattaacgcg ctccccggcg caggaatctg 4680 cgtgtaagga cctggatcgc aatggccaaa gagcggccat cacgccccag gccgcttaca 4740 ctccgatccc taagcgcgcc ggctcgcgct cactttttta aaatggaggt tgaattatgg 4800 cgacgagaga agagatttcg atggttgggt ttgcacttgt ggcttatgca ggggatgctc 4860 ggactgcggc tttgcgtgct ttgaatgctg cagaagcggg tgactttgaa ggagccgagg 4920 ccaaacttga cgaagcgcaa aaagatatta atgaagcaca taatcaacag acgcaattgt 4980 taagccaaga agcaggcgga gcggaaatgg atgtgacttt tatcatggtg catgggcagg 5040 atacgttaat gaccaccatg ttgcttattg atcagtctcg ttacatgatt cgaatgctta 5100 aacgtatcaa gcaactcgaa gacaagcaat aaactaaaac cccaacaccc gcgctcttct 5160 tgtggtaaaa ctgaccaagt gatagcgtct gacctggtaa acatgttgcc atatggatta 5220 aacagcaaaa gcatcggatt attggaggtg agataatctg atgctttttg tatatagtga 5280 tcatgtttct gaatttttta ctaaaacacc agcaaacaaa tcagcggagt tttggaagct 5340 tatttacgga ttgaaaaaat attcgacaat agcgcttcca ttttggagtt aattttagta 5400 aaataaaaac ggttacaaaa atcgacaaat aattgacgcg tttttaaata ttaggaggta 5460 ttggcagtga acagtacaga tgtcacgaaa ggctttacgg agcaatttgg caagcaggca 5520 gaacacactt ttttcgcgcc tgggcgaatt aatttgattg gtgagcacac ggattacaat 5580 ggcgggcacg ttttcccttg tgcgatttcg cttgggacgt atgcagcggt tggggcaaat 5640 gatgacaatg cgttccgttt gtattcggcc aatttcccta aagtgggtat tattgacatt 5700 ccgttccctg atcttttcca ggacaagcgc ggtttgtgga cggattattt tcagggaatg 5760 gcgcgggtca tgaaaacagc aggtatcaat tatacgcatg gcctaaatgt ttatatcaac 5820 ggtaacttac cggatggtgc cgggctatca agttctgctt ctctggaaat gctggtaggc 5880 acgattttga acaacttatt cgatggtggt tttgcaccgc tggacttggt taagttcggg 5940 gttaaagtcg aaaatgatta tattggcgtc aattccggga tcatggatca gtttgcgatc 6000 gaaatgggac gggcaaacca ggcaactttg ctggatacca acaccatgaa gtatgaatat 6060 ttgccggtag aaatgggcga caacgtgatt gtcatcatga ataccaacaa gcgtcgtgaa 6120 ttaaccgatt ctaaatataa cgaacggcgc agcgaatgtg agaaagcttt ggcgatgttg 6180 caaaaaggca ttgatgtcaa gagtcttggg cagctaacgg aagatgaatt tgatgaaaat 6240 acttatttga tctacgacga gacattgatt aagcgtgccc ggcatgcggt atttgaaaat 6300 caacgtacgt taacggctgc taaagcactg cagtcaggag atcttaaaac ctttggcaaa 6360 ttagtttctg cgtcaggcgt ctccttggct tttgattatg aagtgaccgg aattgagttg 6420 gacaccttgg ttaccaatgc tttgaagcaa cgtggtgtgt taggggcgcg catgaccgga 6480 gccggttttg gcggttgtgc catcgctatt gtcaacagtg cagacgttga ggactttatc 6540 agtaacgttg ggaaagctta tactgaaaag atcgggtacg acgctcactt ttacgtagcg 6600 gacattgccg atggtgctaa gcaattgaat tgaggcaaaa aggccaaatg ttcggcttaa 6660 gtaaacgcat cacaaacatt caaaggagcg atttttaata tgacaattgc agttttaggc 6720 ggcgcggggt acatcggttc acacacagtt aagcagttac tggcagatgg agaagatgtc 6780 atcgtcttgg ataatctgat taccggtcat cgtaaggcgg ttgatccacg ggcccggttt 6840 tatcaagggg acattcgcga ttaccatttt ttgagtcagg tttttagcca ggaaaagatt 6900 gacggaattg tgcactttgc ggcattttcg attgtaccgg agtcgatgaa agatccgctg 6960 aagtattttg ataacaatac aggcggcatg attacgctgc ttgaagccat gaatcagttt 7020 gggatcaaga agattgtctt ctcgtcaact gctgccacat atggtgaacc taaacaagtg 7080 ccgatcaagg aaaccgatcc gcaagtgccg actaatccat atggtgaaag taagctggcc 7140 atggaaaaga tcatgcattg ggctgacgtt gcttatggtt tgaagtatgt tgctttgcgt 7200 tactttaatg tggctggggc aatgacagat ggttccattg gtgaagacca tcatccggaa 7260 acccacttga ttccgattat cttgcaggtg gctgcaggta gccgcacagg cttgcagatt 7320 tacggtgatg attacccaac caaagatggt accaatgtgc gcgattatgt gcatgttgtt 7380 gatttggccg acgcacatgt tttggcagtg aaatatttga atgccggcaa tccgtcatct 7440 gcatttaata ttggctctgc tcatggcttt tcaaacatgg aaattctcaa tgctgcgcgt 7500 aaagttaccg gtcaaaagat tccggcaacg gtgggtcccc ggcgtcccgg tgatcctagc 7560 actttggttg ccagttcaga gaaggctcgc gatattctgg gatggaagcc aaactacgat 7620 gacattgata aaattatcga aacggcttgg aattggcatg agaatcatcc ggaaggcttc 7680 ggtgaccgta attgaccgca attagcaatc acattgagac cattatcaag ccgaatcctg 7740 attacacgca gatggatccg gtttatttaa ccaataagtt gcttaattta atcggtgatg 7800 cggcgcttga actgccaggt gatccggatc cgctggataa tctggattta atggtcaaag 7860 ccgcgcaaac gaacggtaaa attgcggatt cgcaggctgc acgccaaatc cttgaagccc 7920 aattaatgga ttttgccacg ccaacgccaa gccggatcaa tcagttattc tgggataaat 7980 atcaggcagg accgcgcgca gccacagatt ggttcttcgc gctaagtcga gcaaacaatt 8040 atattcaaac gcgggccatt gctaaaaacc tggtctttcc tgcaaaaacc gagtatggcg 8100 atcttgaaat cacgatcaac ctatccaaac cggaaaagga tcctaaagat atcgctgccg 8160 ctgcccatgc gcaatcgggt tatccggcgt gtgcactttg cttgcagaca gaagggtatg 8220 ctggccgaag taattttgct gcacgtacta accaccggat tatccgtttc ttgttaggcg 8280 gtaaaacctg gggctttcaa tattcgcctt atgcgtattt taatgaacat gcgatctttt 8340 tggacgctat tcacgagccc atggtgattg accaaagtac ttttaccaac ttgctcgaca 8400 ttgttgccat gtttccagac tattttgtcg gttcaaacgc ggatctacca attgtcggcg 8460 gctcgatgct tgctcatgag cattatcaag gtggacggca cacatttccg atggcgaaag 8520 cgccgatcga aacgcaaatc gagatcagtg ggcatccgca tgtttttgcc ggcattgtga 8580 aatggccgat gagtgtgatt cggctggtca gtgccgatcg cgaagaatta accaatgcgg 8640 ctgaacacat ccggcaggtt tggaatcagt atactgacga agcggttaat gttcgtgctt 8700 ttgtggaggg taagccgcat catacggtga cgccaatcgc tcggcgcgtg ggatcggagt 8760 atcaactgga tctggttttg cgggataatc aaacgagcga acagtatccg gatggtattt 8820 tccacccgca tcaggatgta caacatatta agaaagaaaa cattggctta attgaagtca 8880 tgggtcgggc gattttgcca gcgcggctta agtctgaatt agcagaagtt aagaagtatc 8940 tcttaggcga ggctaatgag atgaagccaa tgcataagac ttgggcagat cagctgaaag 9000 tggcttacaa ttggacaccg gaaaatgcgg aaagtcagtt gcaagaagca gtcggaaaag 9060 tcttcgcccg ggtattggaa gatgctggcg tctttaaacg tgacaagatc gggcaagagg 9120 catttggccg cttctgtcac tcgctatagt tgctggttgt tgttaatggt cagggaaacg 9180 gagggaatcg atgaccacga ttacggatat tgcgaaggcg gcgggggtgt cgatcgctac 9240 ggtttcgcgg attttgaatt atgacgctac actggcagtg acgccggaga cacgccaacg 9300 ggttctaaaa acagccgaga agttggcgta taaaccacgt cgccgcaaac gcgttgctac 9360 tcaaacaacg gtggcactaa ttcagtggcg gagtgaacaa gaggagctta atgacctcta 9420 ttatctgcag attcagtacg ctattgaagc cagggccgca tccattggtt atcatgtgca 9480 aaatctgcac ctggagcaat taaacgcgga aagtgttgca aatgttcagg gtatcattgc 9540 acttggcaag tacgatgcag gtgaggttgc cgaaattaag gcgttagggt tgccgattgt 9600 gtttgttgat cagaatatgc tggcgtttga ttgcgattcc gttaccggcg attatgctgg 9660 cccaattgcc cagatcattg atcattttca gaaggtcggc attgatgata ttggttttct 9720 tggcggattg gaaacgagcc gcagtggacg cgaacagttt caggatgttc ggaccgcgac 9780 atttgatcgt gtgactaaag ctgccggaat cgatcatgcc gagtttcgat tgatcggtga 9840 attcaccccg gattccggtt atcggctaat gcgacaggcc atcgaaaaat taggtgagcg 9900 gttgccacac gcatttatca ttgctaatga cactatggcg gtgggtgctt tgcgggcgct 9960 gaatgaagct aacatttcgg taccgcagcg tgtttcggtc atcagtttta atgatgttgc 10020 cgtggctaag tttacaacgc ccccgttatc gactgtgcat gcagcgaccg atcaaatggg 10080 tcaaactgca gttgagttgc tacaggcgcg cttgaatgat gctaaacggg ttccgcgaca 10140 ggttaatttc aaaagcgagt tgattatgcg cgccagcagt ttgtaggtgg cgtcagcagc 10200 tgtcagatga tgccgcaaga tggctgtgcg atccgtgaac catgatataa ggaggttatg 10260 atggacgttt cagttgagca atatggtcag tatcagggac aaaatcttta tgaattaacc 10320 ctcactaacg accaaggtat ggtagttaag ctgttaaatt atggtgcaac gctggagaag 10380 gtgcttttac cggaagcaga tgggctccac aacatggtgc tgtcattacc aacacgcgaa 10440 gattattcaa aagaacgtaa ttttcttggc ggtacggttg gccgcattgt cgggcgaatt 10500 cgggggcacg tttggcaaca cggtgacgtt aaagtcgatt tgccgatgaa tgaaggcaag 10560 aaccatattc atggcggaga tgatgggctc gatcgtcaag tttacaattt tcgcaccgag 10620 caaactgcaa cgacggcgag tgcgagcttt acttttgttg atccggccgg acacaacggt 10680 tatcccggca atcttaaatt acaggtgact tacacgctga caaacgcgaa tgctttgcag 10740 tatcgcgttg atgcattgag tgatgaggag acgctgttta atccaaccac catacttatt 10800 tttgcactgg atcacccagc tacgattgat gaaaccgtac tgacaattcc agcagatgcc 10860 tataagccct tggacgccga acatcttccg gatcaaggct ggcaaccggt ggcgggtact 10920 gtattggatt ttcgcaacgg gcaaaaactg ggcgatgtca tccatacgcg tgccgatcaa 10980 attacatctg aacgtggcat taatcacccg ttcctcctaa aaaacggcaa agcactagcc 11040 gccaagctgc aaactaaaaa tcacacgatg acacttgtca ccactgcacc aagcgtggtt 11100 gtttatacag ccaatcattt cgatggtaca ggcgttgcgc ataacatcaa gcaatttgat 11160 ggggtagcac ttgaatgcca atatccgcca gtaagcggtt cggatttatc cgcgatcacg 11220 ttgctgccag gtgaaccatt taccttggcg aatacctgga cgtttgaata atagttaacg 11280 acaaaaggct ctttggggat gctcaaaggg cttttttgta tgctggggta tcggtgctgg 11340 ctttctgctt gttgaggcat ggcgtttgtg gagttaggga atcgaaagga tc 11392 // |
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