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EBI DbfetchID AY624354; SV 1; linear; genomic RNA; STD; VRL; 7124 BP. XX AC AY624354; XX DT 15-JUN-2004 (Rel. 80, Created) DT 15-JUN-2004 (Rel. 80, Last updated, Version 1) XX DE Machupo virus strain Chicava segment L, complete sequence. XX KW . XX OS Machupo virus OC Viruses; ssRNA negative-strand viruses; Arenaviridae; Arenavirus; OC New world arenaviruses. XX RN [1] RP 1-7124 RA Hajjaj A., Chain P.S.G., Smith K.L., Imbro P.M., Malfatti S.A.; RT ; RL Submitted (12-MAY-2004) to the EMBL/GenBank/DDBJ databases. RL Viral Sequencing Group, Lawrence Livermore National Laboratory, 7000 East RL Avenue, Livermore, CA 94550, USA XX RN [2] RP 1-7124 RA Jahrling P.B., Geisbert J., Ibrahim M.S.; RT ; RL Submitted (12-MAY-2004) to the EMBL/GenBank/DDBJ databases. RL Viral Genomics Group, USAMRIID, Fort Detrick, MD 21702, USA XX FH Key Location/Qualifiers FH FT source 1..7124 FT /organism="Machupo virus" FT /segment="L" FT /strain="Chicava" FT /mol_type="genomic RNA" FT /db_xref="taxon:11628" FT primer_bind 1..19 FT CDS 96..380 FT /codon_start=1 FT /product="Z protein" FT /note="zinc protein" FT /db_xref="GOA:Q6IUF9" FT /db_xref="InterPro:IPR003224" FT /db_xref="UniProtKB/Swiss-Prot:Q6IUF9" FT /protein_id="AAT45079.1" FT /translation="MGNCNKPPKRPPNTQTSAAQPSAEFRRTALPSLYGRYNCKCCWFA FT DTNLITCNDHYLCLRCHQTMLRNSELCHICWKPLPTSITVPVEPSAPPP" FT misc_feature 394..454 FT /note="hairpin intergenic region" FT CDS complement(465..7094) FT /codon_start=1 FT /product="L protein" FT /note="L polymerase" FT /db_xref="GOA:Q6IUF8" FT /db_xref="InterPro:IPR007099" FT /db_xref="InterPro:IPR010453" FT /db_xref="InterPro:IPR014386" FT /db_xref="UniProtKB/Swiss-Prot:Q6IUF8" FT /protein_id="AAT45080.1" FT /translation="MDEYVQELKGLIRKHIPDRCEFAHQKVTFLSQVHPSPLLTEGFKL FT LSSLVELESCEAHACQANTDQRFVDVILSDNGILCPTLPKVIPDGFKLTGKTLILLETF FT VRVNPDEFEKKWKADMSKLLNLKHDLQKSGVTLVPIVDGRSNYNNRFVADWVIERMRWL FT LIEILKASKSMLEIDIEDQEYQRLIHSLSNVKNQSLGLENLEHLKRNSLDYDERLNESL FT FIGLKGDIRESTVREELIKLKMWFKDEVFSKGLGKFKLTDRRELLESLSSLGAHLDSDV FT SSCPFCNNKLMEIVYNVTFSSVERTDGAATVDQQFSTTHTNIEKHYLSVLSLCNKIKGL FT KVFNTRRNTLLFLDLIMVNLMVDISESCQDAIESLRKSGLIVGQMVMLVNDRVLDILEA FT IKLIRKKIGTNPNWVKNCSKILERSHPEIWLQLNTLIRQPDFNSLISIAQYLVSDRPIM FT RYSVERGSDKICRHKLFQEMSSFEQMRLFKTLSSISLSLINSMKTSFSSRLLVNEREFS FT KYFGNVRLRECYAQRFYLAESLVGFLFYQKTGERSRCYSVYLSDNGVMSEQGSFYCDPK FT RFFLPVFSDEVLAGMCEEMTSWLDFDTGLMNDTGPILRLLVLAILCSPSKRNQTFLQGL FT RYFLMAFANQIHHIDLISKLVVECKSSSEVVVQRLAVGLFIRLLGGESDASSFFSRRFK FT YLLNVSYLCHLITKETPDRLTDQIKCFEKFIEPKVKFGCAVVNPSLNGKLTVDQEDIMI FT NGLKKFFSKSLRDTEDVQTPGVCKELLNYCVSLFNRGKLKVSGELKNNPFRPNITSTAL FT DLSSNKSVVIPKLDELGNILSTYDKEKLVSACVSSMAERFKTKGRYNLDPESTDYLILK FT NLTGLVSAGPKAKSSQEELSLMYETLTEEQVESFNEIKYDVQVALAKMADNSVNTRIKN FT LGRADNSVKNGNNPLDNLWSPFGVMKEIRAEVSLHEVKDFDPDVLPSDVYKELCDAVYK FT SSEKCNFFLEEVLDVCPLGLLLKNLTTSSYMEEEYFMCFKYLLIQGHFDQKLGSYEHKS FT RSRLGFTDETLRLKDEVRLSIRESNSEAIADKLDKSYFTNAALRNLCFYSEDSPTEFTS FT ISSNSGNLKFGLSYKEQVGSNRELYVGDLNTKLMTRLVEDFSEAVGNSMKYTCLNSEKE FT FERAICDMKMAVNNGDLSCSYDHSKWGPTMSPALFLALLQMLELRTPVDRSKIDLDSVK FT SILKWHLHKVVEVPINVAEAYCIGKLKRSLGLMGCGSTSLSEEFFHQTMQLSGQIPSHI FT MSVLDMGQGILHNTSDLYGLITEQFLCYALDLLYDVIPVSYTSSDDQITLVKTPSLDIE FT GGSDAAEWLEMICFHEFLSSKLNKFVSPKSVIGTFVAEFKSRFFVMGEETPLLTKFVSA FT ALHNVKCKTPTQLSETIDTICDQCIANGVSTKIVARISKRVNQLIRYSGYGDTPFGAIE FT DQDVKDWVDGSRGYRLQRKIEAIFYDDKETSFIRNCARKVFNDIKRGRIFEENLINLIG FT RGGDEALTGFLQYAGCSEQEVNRVLNYRWVNLSSFGDLRLVLRTKLMTSRRVLEREEVP FT TLIKTLQSKLSRNFTKGVKKILAESINKSAFQSSVASGFIGFCKSMGSKCVRDGKGGFL FT YIKEVYSGINVCICEICALKPKIIYCNDSLNKVSQFSKPILWDYFSLVLTNACELGEWV FT FSTVKEPQKPLVLNNQNFFWAVKPKVVRQIEDQLGMNHVLQSIRRNYPVLFDEHLAPFM FT NDLQVSRTMDSGRLKFLDVCIALDMMNENLGIISHLLKTRDNSVYIVKQSDCALAHIRQ FT SSYTDWELGLSPQQICTNFKTQLVLSSMVNPLVLSTSCLKSFFWFNEVLELEDDSQIEL FT AELTDFALMVKNQNVSRAMFVEDIAMGYVVSNFEGVRISLSNVMVDGVQLPPKEKAPDV FT GVLFGLKAENVIVGLVVQIDHVRMSTKFKLRRKMVYSFSLECTMDVGDIQNKEVILKVV FT AVDQSVSGSGGNHMLLDGVPVIASLPLFTGQASFDLAAMLIESNLAGSNDNFLMSNVTL FT DLGGFSPELSDKYSYRLSGPENQEDPLVLKDGAFYVGGERLSTYKVELTGDLVVKALGA FT LEDDEGVVSMLHQLWPYLKATSQVILFQQEDFTIVHDLYKIQLTKSIESFGEWIEFTNF FT KVAYSKSLKELVISDTQGSFRLKGVMCRPLANTLQVEDIE" FT primer_bind complement(7106..7124) XX SQ Sequence 7124 BP; 2107 A; 1695 C; 1180 G; 2142 T; 0 other; cgcacagtgg atcctaggcg taactggatc aagttttgct gagtaaaatt ttaacacatt 60 gagtgtccgt gcaaaacagc gcagggctcc ccacaatggg caactgtaac aagcctccca 120 agaggcctcc caacacacaa acatcagccg cccagccctc agcagagttc aggagaacag 180 ccctacccag tctctatggt cgctacaact gcaaatgttg ttggtttgcc gacacaaact 240 tgattacatg taacgaccac tacttgtgtc tgagatgtca tcaaacaatg ctcaggaatt 300 ctgaactctg tcacatatgc tggaaaccac taccgacatc catcacagtc cccgtggagc 360 caagcgcccc cccaccatga acatccccaa acccggtcca caggaccccc ggggggcccc 420 aacggggccc ccacggggga tccccggggg ttttcttggc tgcgtcactc gatgtcttcc 480 acctggagcg tgtttgccag gggtctacac atcacaccct tcagtctgaa tgacccttgg 540 gtgtctgata tcacaagctc tttgagtgat ttgctatagg caaccttaaa gttggtgaat 600 tcgatccatt caccaaagct ttcaattgat tttgtgagct gtatcttgta caaatcatga 660 acaatagtga agtcttcctg ttgaaacaaa ataacctgtg atgttgcttt caaataaggc 720 cacagttgat gcagcataga aacaacaccc tcatcatctt ctagggcccc caatgctttc 780 accacaaggt cacctgtaag ctctacttta tatgtggaca gtctctcacc tcccacatag 840 aaggcaccat ccttcagaac caacgggtct tcttggtttt caggtcccga gagcctgtag 900 gaatatttgt cactcaactc tggggaaaat ccacctaaat ccaaggtaac attgctcatt 960 aagaaattgt catttgaacc agctaaattt gactcaatta acattgcagc caaatcaaaa 1020 ctggcctgcc cagtaaataa tgggaggctt gcaataactg gcacaccatc cagcagcata 1080 tggtttcctc ctgacccaga cacagactga tcgactgcca ccaccttcaa aatgacctct 1140 ttgttctgga tatctcctac atccattgtg cattccaaag agaagctata caccattttt 1200 ctcctcaact tgaacttcgt tgacattctt acatgatcga tctgcaccac taaacctaca 1260 atgacatttt cagccttcaa tccaaacaat acacctacat caggagcctt ctccttaggc 1320 ggcaattgaa caccatcaac catcacgttg cttaacgaga ttctaacacc ctcgaagtta 1380 gagacaacat accccattgc gatatcctcc acaaacatag ctctggaaac attttgattc 1440 ttaaccatta aggcaaaatc agtcaattct gctaactcaa tttgactatc atcctctagc 1500 tctagaactt cattgaacca gaaaaatgac ttcagacaag atgttgatag gactaatggg 1560 tttaccattg acgacaggac caactgggtc ttgaagtttg tgcaaatctg ctgcggacta 1620 agtcccaact cccaatctgt atagcttgac tgcctaatgt gtgctaaggc acaatcactt 1680 tgtttaacta tgtaaacact gttgtctctg gttttcaaca ggtgactgat gataccaagg 1740 ttttcattca tcatgtctaa agcaatgcaa acatccagaa attttagcct cccgctatcc 1800 attgttctgc tgacctgaag atcattcatg aatggagcca agtgttcgtc aaagagaact 1860 ggataatttc tccttataga ttgcagaaca tggttcattc ccagttggtc ttcaatttgt 1920 ctcaccactt taggcttcac agcccaaaaa aagttttggt tgttcaacac taatggcttt 1980 tggggctctt taactgtaga aaacacccat tctccaagtt cacatgcatt tgttaggact 2040 aatgaaaagt aatcccacaa aataggtttt gaaaactgac tcactttatt aagtgagtcg 2100 ttgcaatata tgatcttagg ctttaacgca catatttcac atatgcaaac atttataccc 2160 gaatacactt cttttatgta taaaaatcct cccttcccat ctctaacaca cttgctaccc 2220 atacttttgc agaaaccaat aaaacctgag gcaacggatg actggaaagc tgatttatta 2280 attgactcag caaggatttt cttaactcct tttgtgaagt ttctggaaag tttggactgc 2340 aaggttttaa ttaatgttgg cacttcctcc ctttcaagaa ctcttctact tgtcatcaac 2400 tttgtcctca aaactaacct aagatctcca aaacttgata aattcaccca tctatagttc 2460 aacacacgat taacttcttg ttcactacaa cctgcatact gtaaaaaacc agtcaaggcc 2520 tcatcaccac ctctaccaat caaattgatc agattctcct caaatattct gccacgcttt 2580 atatcattaa aaacctttct ggcacagttc ctaataaaag aagtttcttt gtcatcataa 2640 aaaatagctt caatttttct ctgtagacgg taaccccttg agccatccac ccagtctttc 2700 acatcttggt cttcaatggc cccaaaggga gtgtctccat acccggagta tctaattaac 2760 tggttaactc gttttgatat tcttgccact attttggtgc tgactccatt tgcaatgcat 2820 tgatcacaga tggtatctat agtttctgac aattgtgtgg gtgttttaca ctttacatta 2880 tgtaaagctg cagaaacaaa ctttgtgagc aatggtgttt cttcacccat gacaaaaaat 2940 cttgatttga actctgcgac aaaggtcccg atgacactct tgggactgac aaacttattc 3000 aatttagatg acagaaactc atggaagcag atcatctcga gccactccgc agcatctgaa 3060 cccccttcta tatccagaga aggtgtcttg acaagagtaa tctgatcgtc actagaggta 3120 tatgacacag ggattacatc atacaaaaga tcgagtgcat aacacaaaaa ctgctctgta 3180 attaatccat acaaatcaga agtgttatgt agtatccctt gccccatgtc caaaacagac 3240 ataatgtgac taggaatctg accactcagt tgcatagtct gatggaagaa ctcttcactc 3300 aaactggtgg agccgcagcc catcaatcca agggaccttt tcagctttcc aatacaatag 3360 gcttcagcca cattaatagg tacttctaca actttgtgaa ggtgccattt cagtatactt 3420 ttaacagaat caagatcaat ttttgacctg tcaacagggg ttctcaattc tagcatttgt 3480 aataatgcca ggaaaagtgc aggactcatt gttggacccc attttgagtg atcataagaa 3540 catgacaaat caccattatt cactgccatc ttcatgtcac aaattgcccg ttcaaattcc 3600 ttttcagaat ttaaacaggt gtacttcata gaattcccca cagcttcaga aaaatcctcc 3660 accaatcttg tcatcagttt tgtgttgagg tctcctacat agagctctct gtttgaaccc 3720 acctgttcct tataacttag accaaattta aggtttcctg agttggaact aatacttgtg 3780 aactcagtgg gcgaatcttc agaataaaaa cacagattcc ttaatgcagc attggtgaag 3840 taacttttgt ccaacttgtc tgcaatcgcc tctgagttac tttctcttat actaagtcta 3900 acctcgtctt tgagtcttaa cgtctcatcg gtgaaaccca gtctagatct gcttttgtgc 3960 tcgtaacttc ctaatttttg atcaaagtga ccttgtatca agaggtattt aaaacacata 4020 aaatactctt cttccatata acttgatgtg gtcagatttt tcaacagcaa ccccaaggga 4080 caaacatcaa gtacttcctc aaggaaaaag ttgcattttt ctgacgattt gtaaactgcg 4140 tcacacaact ccttgtacac atcagaagga agaacatctg ggtcaaaatc cttgacttca 4200 tgtaacgata cttcagccct aatctctttc atcaccccaa aaggtgacca cagattatcc 4260 aaaggattat tcccattttt tactgagtta tcagctcggc cgagattttt aattcttgtg 4320 ttcacactgt tgtcagccat cttggctaag gcaacttgca catcatattt aatttcattg 4380 aatgattcaa cctgttcttc tgttaacgtc tcgtacatta aagacaattc ttcttgacta 4440 cttttagctt ttggccctgc actcaccaaa cctgtcagat tttttaaaat caaatagtca 4500 gttgactccg gatctagatt gtaccttccc ttggttttaa atctctctgc catagaggaa 4560 acacatgctg acaccagttt ttctttgtca taggtggaga ggatgttacc taactcatct 4620 agttttggta taacaacact cttgttactt gataagtcta aagcagtact tgttatatta 4680 ggtctaaagg gattattctt aagctcccca gaaaccttta actttcccct attaaacaaa 4740 gacacacaat agtttaaaag ttctttacac acacctggtg tctgcacatc ctcagtgtcc 4800 cttaaggatt ttgagaaaaa ctttttcaac ccatttatca taatgtcttc ctgatctaca 4860 gtcagttttc catttagaga tgggttcacc acagcacatc caaacttaac tttgggctca 4920 atgaacttct caaaacactt gatctgatct gtcaatctgt caggtgtttc ctttgtgatt 4980 aaatgacaaa ggtaactaac attcagcaga tatttgaatc ttcttgagaa aaatgaactt 5040 gcatctgact caccaccaag tagtctaatg aagagtccca ctgcaagcct ttgaaccacc 5100 acttctgaac ttgatttgca ttccactacc aatttagata ttaggtcgat gtgatgaatt 5160 tggttagcaa aagccattaa aaagtacctc aatccttgta gaaaggtttg attccttttt 5220 gacggagagc agagtatagc tagaactaac aaccttaata tgggcccagt atcattcatt 5280 aatccggtgt caaaatccag ccagcttgtc atttcttcac acattccagc caaaacttca 5340 tcagaaaaaa caggcaagaa gaatctcttt ggatcacaat aaaatgaacc ctgttctgac 5400 atcacaccgt tgtcagataa ataaactgaa taacacctgg atctttcacc tgtcttctga 5460 tagaaaagaa acccaactaa actctcagcc aaataaaacc tttgggcata acattctctg 5520 agtctaacat taccaaagta cttagaaaac tctctctcat tcacaagcag tcttgaagaa 5580 aaggatgtct tcatagaatt gattagtgac aaggatattg aggacaaagt cttgaataac 5640 ctcatttgct caaagctaga catctcctgg aataatttat gtctacagat cttatcagag 5700 cctctttcca ctgaatatct catgattggt ctatctgaga caagatattg ggctattgaa 5760 atcaagctat taaaatctgg ttgccttatc aaagtattta attgaagcca aatttctgga 5820 tgtgatctct ctagaatctt tgaacaattc ttgacccaat tgggattagt cccaatcttt 5880 tttctgataa gtttaatagc ctccaaaatg tccagcactc tatcattcac taacataacc 5940 atctgaccca ctatcaatcc tgattttctc aagctttcaa tagcgtcctg acaactctca 6000 ctaatgtcaa ccatcaaatt aaccattatg agatctaaga atagtagggt gtttcttctg 6060 gtgttaaaga cctttaaccc ctttatttta ttgcacaaag ataagacact aaggtaatgt 6120 ttttctatat tagtgtgtgt ggtgctaaac tgctggtcca ctgtggctgc accatcagtc 6180 ctttcaacac tgctaaaggt aacattgtaa acaatttcca tcaacttatt gttacaaaag 6240 ggacagcttg acacatcact gtccagatga gcacctaagc tcgataggga ctctaataac 6300 tcccttctgt cagtcaattt gaatttgccc agacctttgc tgaagacctc atccttaaac 6360 cacattttga gtttgatgag ttcttccctc actgttgact ctctaatgtc tcctttcaaa 6420 ccaataaata atgactcatt caacctctca tcataatcta gggaattcct tttcaaatgt 6480 tctaggtttt ctaaccccaa gctttgattc ttaacgtttg ataggctatg aattaatcgt 6540 tgatattcct ggtcctcaat atcaatctca agcatggatt tggatgcttt caaaatctca 6600 ataagcaacc atctcattct ctcaatcacc caatcagcaa caaatctatt gttgtaattg 6660 cttctaccat caacaatagg aaccaaagtc acgcccgact tctgcagatc atgcttcagg 6720 tttaaaagct tcgacatatc agctttccat ttcttctcga actcatctgg gtttactctc 6780 acaaaggtct ccagcagaat tagggttttc ccagttagtt tgaacccatc agggatcacc 6840 tttggtaaag ttggacataa gattccattg tcggatagta ttacatctac gaatctttga 6900 tcagtgtttg cctggcaggc gtgtgcttca caggactcaa gttcaacaag actagaaagc 6960 agcttaaagc cttctgtgag caagggactg ggatgcacct gagataggaa tgtaaccttt 7020 tgatgtgcaa actcgcacct atcgggaatg tgctttctaa taagcccttt caattcttgg 7080 acatattcat ccatggccaa gtgtcgccta ggatccactg tgcg 7124 // |
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