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EBI DbfetchID AY230145; SV 1; linear; genomic DNA; STD; INV; 7496 BP. XX AC AY230145; XX DT 26-JUL-2003 (Rel. 76, Created) DT 26-JUL-2003 (Rel. 76, Last updated, Version 1) XX DE Leishmania major clone B3558 divergent H4 histone pseudogene, complete DE sequence; and phosphoglycan beta 1,3 galactosyltransferase 2 (SCG2) gene, DE complete cds. XX KW . XX OS Leishmania major OC Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Leishmania. XX RN [1] RP 1-7496 RX DOI; 10.1074/jbc.M301568200 RX PUBMED; 12604613. RA Dobson D.E., Scholtes L.D., Valdez K.E., Sullivan D.R., Mengeling B.J., RA Cilmi S., Turco S.J., Beverley S.M.; RT "Functional identification of galactosyltransferases (SCGs) required for RT species-specific modifications of the lipophosphoglycan adhesin controlling RT Leishmania major-sand fly interactions"; RL J. Biol. Chem. 278(18):15523-15531(2003). XX RN [2] RP 1-7496 RA Dobson D.E., Beverley S.M.; RT ; RL Submitted (04-FEB-2003) to the EMBL/GenBank/DDBJ databases. RL Molecular Microbiology, Washington University School of Medicine, 660 S. RL Euclid Ave., Box 8230, St. Louis, MO 63110, USA XX FH Key Location/Qualifiers FH FT source 1..7496 FT /organism="Leishmania major" FT /strain="Friedlin V1" FT /mol_type="genomic DNA" FT /clone_lib="genomic library in cLHYG vector [Ryan et al. FT (1993) Gene 131: 145-150]" FT /clone="B3558" FT /db_xref="taxon:5664" FT gene 385..635 FT /pseudo FT /gene="divergent H4 histone" FT CDS 385..635 FT /pseudo FT /codon_start=1 FT /gene="divergent H4 histone" FT /note="variant 5' end containing numerous deletions and FT frameshifts; divergent H4 histone" FT gene <2515..>4959 FT /gene="SCG2" FT mRNA <2515..>4959 FT /gene="SCG2" FT /product="phosphoglycan beta 1,3 galactosyltransferase 2" FT CDS 2515..4959 FT /codon_start=1 FT /gene="SCG2" FT /product="phosphoglycan beta 1,3 galactosyltransferase 2" FT /note="glycosyltransferase" FT /db_xref="GOA:Q7YXV3" FT /db_xref="InterPro:IPR002659" FT /db_xref="UniProtKB/TrEMBL:Q7YXV3" FT /protein_id="AAP55678.1" FT /translation="MREENNVPAEWAPRDTHRLDPLQLLPPSQRHCGQSSAAESGEGCH FT SRSRGKPEVHSTRASSGGKRSTGTLPRSDDCLNAVAQTPLFNSCGHPRRSAAQCLRLCT FT RQRRLAALAVLLALIVMVHWVISQFTTNVGLQQKSSIELLNEANREYESSSPFSVLVQH FT ESAVERLTTTQRGLAASGAGSLARLDRDQLPSWTLRVIDEDCTMCFDNVTYASAVAADA FT GRSTNKTGHHKQKGLSVFATTSAPLGLMGPMLFAMASVTDDVDVAAELPRWQWVTWSYA FT QQRRFVHTSQSRSTGERPRHLIVLGIPSTDQPMRYPLRDAQRATWLTYREVARTENNFT FT GALLQLYVFAAAHRDSDYTAQYLGDTAQVAPTVSEYAAATEQHLAVEGGDVNNAPPYLQ FT CRVVLRDGWRDIPRSDDAVWRSPCAGVRTTVVTAASLVAGTSSLTVFSAQLSLPVTPAF FT TAAAQYVCHASAALWQEALHHRNSLWLDFLTDRKPTTKKKMGMGISWGIPTEVGMSQKT FT VLWLNYAYTAFPDVPYIMKGDDDMYLKVPQYLSDLRHVRGGWQKPRNLTVTIPHRGVIP FT PTLAINDAEECLYRVWWLYRSKLAYGNGVGYILDRRLIQAALNPFDDFNALLMKLLTNP FT YDYRLEKEYLSLNMQHEDKHIGKQIRDHHDAVERFCPKKRVCYMADRRFRAHQILRPKP FT VKLTWISVMAHFGMSAIPYYVHYFHKNEFKVAEEAKRLIAQGIDVNTIEENATQRMHEW FT VASQVPSTLVGLGASFDLDWVRGDPRTAYTVAEEDEVAVYDVRYKLRRRNDIACVLESD FT KR" XX SQ Sequence 7496 BP; 1471 A; 2247 C; 2056 G; 1722 T; 0 other; aagcttgctt tcgcattgat tcttgagaag acaattaccg cttggggcat ttgtgatcct 60 taccgccgcc gaaaagtacc gtctttcctc agctttcagc gaaaaaaggg actgtttttc 120 tccgcccctt ttccctgagc ttcgccaaca gacttttcta aactgctttc ttctccaagc 180 agcatatgag gtgcaaggca tagctgtaac acttgctctg tgaatactga attatcattt 240 tcggcaatag ctaagtttcc ctgcgaaaat tccacgctgc tttcatccac attcccgccc 300 ttctcgaaac ctgatagcat gaacagcagc acttttattc tcagagatcg aaacctatct 360 gcttcctccc tccatacctt cacaatggcc aagggcaacc agaggcgcca gaagaaggtg 420 ctgccgacaa catccgcggc atcactcgcg gcggcgtgaa gcgcatctcg agcgaggtgt 480 acgaagaggt gcgccgcgtg ctgaaggcct acgtggagga cattgtgcgc tgcagcacgg 540 cctacaccga gtacgcgcgc aagaagaccg tgacggcgtg cgatgttgtg accgcgctgc 600 gcaagcaagg ccacatcctg tacggctacg cgtaaatgct cgcagagccg ctgcacactc 660 atagatacac cttctttgtt catgccgtcg tttcggtggt gttcttggtt ttcgacttct 720 cctcccccca ctatggcttt tctttcgtct cgtgctgaca tccttcccta ctcatcgctg 780 tttgcggaag gcagtaccga aagaagacag cacaccgact ccactgcata cccgaagaga 840 ggccgtgcgc tgccgtatgc gaggcacgct ctcggcgtcc gtgtctatgg aggctgagtg 900 caaccccgct ccctccctgt ctccctcaac gcctgccggc accagaggtc accacgcggg 960 atgacgggtc gtctcttcga cgttgctgct cctccgccgc ttgctcgctc attccctacg 1020 ccgcagcgcc atgcgctccc tttcactcct tgcgcttctc ttcgtctcct cctgttctct 1080 gtttacacac ataacacgca cgacctcaca gacggaagca ccccaatgca gaggacgcgc 1140 ggggtcgtgc atccactgct cagcttcgtg aggcagatgc cgggcggcga tgggtgcttt 1200 tcactgacac tcgagccagc gggcaagaga gcgcagccgc acacctaacg gcgcgagtca 1260 cgggagaaaa agtacgagct cagagaaagg cacacctgcg accgcctttt ctcgctttct 1320 tcggtcttca tacacctatg gcggtctcct ccttcccgac ttctcaaggt agacgtcctt 1380 tctgttgcac cctcacccgc gtgcgcgcgc gtaagtggcg gattgtgacg cggacgaaat 1440 ccagctcgcc aggcgctgct cctttttcct ttcccggtcc ctgtgcccgc cggtggggag 1500 gttcagcagc ctatttctcg atggcattgt tggtttggcc tttgcggttc tttttctgct 1560 ggtcgacgct gctggctgtt ttgtgcttcg ctgtggtgta cagcgcgtcg tggcgcggcg 1620 ctgttctctt tcgcgttttc tgcacggcct gcccgccgta cgccacgtgc tctgtctatc 1680 aagcggtaga ccatccgggt acaggctcga tttccctccc cgacgacagt gcacccgtcc 1740 aacgcgcgcc gccctcttcc cttgcacctc tgccactttt gctttcctct cctgcgcgtg 1800 tgtctactcc tctgcttctt ctcgcgtaga gggggagggg gcaccgacac tgctggcgcg 1860 tctcccactg gagtacgtgc aggccctccc gcttttctgt taggcgctgg gggcttgcca 1920 tcgatccgcg acggatgcca gcgaagggtg cagcggggta gctgccgcgt gcatccttgc 1980 aaaggaaaga cttgcccgct ttcgtctcgg gaaagagaaa cccagagacc tgctgtgtcc 2040 agcaacagtc tgcaccgcca aagaggcaaa cagcctcccc attcccacag cgccgcaccg 2100 gtgttgctcg acgcagtgac atcttccact gccgcttcga ctcgtccgac tcgcgagtcc 2160 ttcgaccatc tcacggcgcc caccttccca caactcactc cacccatctc tccatctctc 2220 catacaccca cccacccaca ccgacacaca ggcacatgca agtggagggc gacacacgtc 2280 cgctgactcg cgcgcccttt gcagtcgcac ggatacgctc acagctcttc ttcaccgctg 2340 tcttgtgttg ccgtgcgatc ctcttgggcc gccctcgatc cacctgcgtc tctgtcggtg 2400 gtcctgctgt ttcgctgtac gcagccaaga gtgtgcttgt gccactttgc cggccacttg 2460 cacaccttag gcactccttc cgccaccccc gcactgcgcg ggaagtacac catcatgcga 2520 gaggagaaca atgtgccagc ggagtgggct cccagggaca cgcaccgcct cgaccctctt 2580 cagctgcttc ccccctctca gaggcactgc gggcagagca gcgctgcgga gagcggagag 2640 ggctgtcact cgcgctcacg cggcaagccg gaggtgcact cgactcgagc gtcgagcggt 2700 ggtaagagga gcaccggcac actgccgaga agcgatgact gcttgaatgc cgtagcacag 2760 acccccctgt tcaactcctg cggtcatcct cgacgatccg cggcacaatg tctgcgttta 2820 tgcactcgac agcgtcgtct ggctgcgcta gccgtcttac ttgctctcat cgtcatggtt 2880 cactgggtca tcagccaatt cacgaccaat gtaggcttac aacagaaatc atcgatagag 2940 ttgctcaatg aagcgaaccg tgaatatgag tcttcatcgc cgttctctgt cctggtgcag 3000 cacgagagtg ctgttgagcg gttgacgacc acacagcgtg gtcttgcggc ctctggcgct 3060 ggctctctgg cgagactcga ccgggatcag ctgccgtcat ggacgttacg tgtgatcgac 3120 gaggactgca cgatgtgctt cgacaatgtc acatacgctt ctgcggtcgc tgcggatgcg 3180 gggagatcga ctaacaagac gggacatcat aagcaaaaag ggctttccgt gttcgcgacg 3240 acatctgcac cgctgggcct catggggccg atgctgtttg cgatggcgag cgtgacggac 3300 gacgtggacg ttgcagcgga actgccgcgg tggcaatggg tgacctggtc gtacgcgcag 3360 cagcgccgct tcgttcacac atcgcagtcg cgcagcacag gtgagcgacc gagacacttg 3420 atcgtgttgg gcataccttc aacggaccaa ccgatgcgct accctctgcg ggacgcacag 3480 cgggcgacgt ggctgacgta ccgagaggtt gcacgcaccg agaacaactt tactggcgcg 3540 ctgctgcagc tctacgtgtt cgctgctgca caccgagatt ctgactacac agcgcagtac 3600 ctcggggaca cggcgcaggt ggccccgaca gtgagcgagt acgccgcagc aactgagcag 3660 cacttggctg tggagggtgg agacgtcaac aatgcacccc cctacctgca gtgtcgcgtg 3720 gtgctgcgtg atgggtggcg cgacatccca cgaagcgatg acgcggtgtg gagatcaccc 3780 tgcgctggtg taaggaccac cgtggtgact gcggcaagtc ttgtggccgg gacctcgtcc 3840 ctcacggtct tttcagccca gttgtcgctg cccgtgacac ctgccttcac agcagcggcg 3900 cagtacgtgt gccacgcgtc cgcggcactg tggcaggagg cgctgcacca tcgcaactcg 3960 ctatggctgg actttttgac ggaccgcaag ccgaccacga aaaagaaaat gggcatgggt 4020 atatcgtggg gtataccgac ggaagtaggc atgtctcaaa agaccgtgtt gtggctgaac 4080 tacgcgtaca ctgccttccc ggacgtgccg tacatcatga agggcgacga cgacatgtac 4140 ctgaaggtgc cacagtactt gagcgacctg cggcatgtgc gcggtgggtg gcagaagccg 4200 cgcaacttga cggtgacgat tccacacaga ggggttatcc caccgacact ggccatcaac 4260 gacgcggagg aatgcctgta tcgagtgtgg tggctctata gaagtaaact cgcgtatggc 4320 aacggcgtgg gctacattct ggaccgtcgc ctcatccagg ctgcactgaa cccgtttgat 4380 gacttcaatg ctcttctgat gaagctgctg acaaatccct acgattacag gctggaaaag 4440 gaatatctta gcttgaacat gcagcacgag gataagcata tcgggaagca gataagagat 4500 caccacgacg ccgtggagag gttctgcccc aagaagcgcg tgtgctacat ggctgaccgg 4560 cggttccggg cgcaccagat tctgcggcca aagcctgtca agctgacgtg gatctcggtg 4620 atggcgcact ttggcatgtc agcgattcca tactatgtcc actacttcca caaaaatgag 4680 ttcaaggtgg ccgaggaggc caagcggttg attgcgcagg gcatcgacgt gaacacgatt 4740 gaggagaatg caacgcagcg aatgcacgag tgggtggcgt ctcaggtgcc gagcacactc 4800 gtggggctcg gagcgtcatt cgatctcgac tgggtacgcg gagacccacg cactgcgtac 4860 actgtagccg aggaggacga agtcgcggta tacgatgttc ggtacaagct ccgccgaagg 4920 aacgatatcg cgtgtgtctt ggagtctgat aagaggtaga ttggcctcca ttgtgccagc 4980 cctccagccc cgtttgtgct ctttctgcgt tgtctcttgt gacgtcgagg ttgtgttcaa 5040 gcgacacggc gattggaagg gtacggaaat gtgacgccag cgattcggct ctaaactcac 5100 caccgttctg gtggttttgc tttccagagt tcaagtacct tccttatcat tgcgctgctg 5160 taacagctac accttcgttc gtcttttctt ttgcttggcg ctagggcact gatggtcggc 5220 tttcactggt gtttttgccg ttctgaggcg tgcacctcat gatgagatgt gctgtgcatt 5280 gctccaagtc attgcttttc ctgtcgccgt gttttctttt ccttctcttt cctgatgcag 5340 tgaagctagc tctctctgtg ttgctctctc ttcctttacg tcgtacatca gacgtgttct 5400 aacctctacc tttaggaggc cctctaaaca actgtgttca gctcgactag gtgaggacaa 5460 gaggcgcgtt gggagcaatg gacttcacaa agagtcggta gcgtggagag agcgcggctt 5520 cttctatccc aattcttctg taacagatgc aagccataga caatgtgccg cccctatctc 5580 tctctctcac atctgctgtc tctggtttga attctgatga ttgctttctc atgcaaacag 5640 cgaccgcccc gccgagcctt cgccgtgcgt tacagatatg tttctttgtt tcattcaccc 5700 tcttcgcacc tacgctcccg attgttgttt ctttgttgac ttttgttttg tttccgtctt 5760 cctccgcatt catgacacgc gtgtagtgtt cgctcatctc taattgtttt ctttccgtct 5820 tcctctcatt catgacacgc gtgtagtgtt cgctcatctc taattgtttt gtttccgtct 5880 tgttccgtta tttcttcttg tcctttgtga tacaatgcaa tgttccatgt gtacgagtcg 5940 cacgcatagt tgccgacgag gtggttgggc ggcgagcagc ttgcaaaaaa aagagagagg 6000 aaaaaataaa aacataccca gagacaaaaa acgtgaacac cataacagac gggcgagggc 6060 ccgccttcgt gtggcgtttt ctgtgacggc gcatcccagg tgtccgttac ttgcatgaag 6120 atgagcctgt cttggagggc tgtgtgcagt cctgcacgaa cgcgtaagcg gtgctctaca 6180 acctgtcctg cgcctgagcc accaacgctg tttcgcttcc agatccgccg ccagtaccgc 6240 gtctccctct cccctccctc gcccttctac tcgcatcaca tccttttggc agccgttacg 6300 tgagttcctt tcactacaca gcacacgcaa gaaggcggcc gaatgctccc gtggtacatg 6360 ccgggctgtc accgaaagaa aaaacaaaac tatctcgtgc tctggactcg ttaccgcgga 6420 ctccttggcg tgcctttcgc cccgcctttg cccgcctccc tcttacttga cactgcggtg 6480 gcaccagtga gtggagtgtg tgcgcgtgtg acgaatcctg aaaacccatc cgggagtaat 6540 gtcggacaac gaatgtccca gaggaccgtg tcgcgcggca agcgacggcg gccgtgggtt 6600 ggaggcagac cgtggaatgc gtacggaggg cagcagcgcg aatgactgcc ggtgcggttc 6660 ccgattcgca cgcttgcttt tccttgcgcc actcagtagg ctcgacgcta gctgtctggc 6720 gaagactcgc cgatctgggc ggctgcatat tgaggcgtgg aagaaaatgt agtcacccag 6780 gtgctctgcg ggaaaaagaa cagcgctctg cataggccgt gtgatgcggc gatgagggac 6840 ctggactctt ccgtgaatcc cataagcgcc ttacagtggc tcaacagaga atcgcttccc 6900 caaacaccac gccctccagc gtccggcacg ggttgtgctc acaaggtctc atagcgcagt 6960 cttcgataca cttgcatcgc aaggtgcagg cagtagcgcc gacgaggagg gggaaaagag 7020 gcccgaaggt tgcactattc gacacgcaaa ccggatctca cgtgtggaaa catgaccaag 7080 gcagccagcg gagctgtgaa gtagccgatg cgatactctg cagtgactgt gtgcaggttg 7140 acaacatgcg gagggtgtct gctgtgcgag cggacactca caatctgtcc ctagtcgtgc 7200 tgccagctgc aaagtagact ctctgtctgc cgatgacact atgaacgcaa cctcgctcac 7260 tgtctgcggt cgcgccaagc cttcccctct ttgcagaagc ctttctatga caactggaga 7320 gacgcgcagg agtagtgcgc cgcgcaagtc tgtacgcagc aaacaagcat tgttcagctg 7380 cactacccac tgctgcccga caggggcact cgagttactc agactccacc tttccattgc 7440 agtgatggag ggtctggtgg gcagggcggc aggcacgatg aaaaagcgag tgatcc 7496 // |
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