 |
|
EBI DbfetchID AY130996; SV 1; linear; genomic DNA; STD; FUN; 5609 BP. XX AC AY130996; XX DT 29-DEC-2002 (Rel. 74, Created) DT 16-APR-2005 (Rel. 83, Last updated, Version 3) XX DE Pneumocystis jiroveci serine endoprotease Kex1 (Kex1) and thioredoxin DE reductase Trr1 (trr1) genes, complete cds. XX KW . XX OS Pneumocystis jirovecii OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; OC Pneumocystidomycetes; Pneumocystidaceae; Pneumocystis. XX RN [1] RP 1-5609 RX DOI; 10.1128/IAI.71.1.571-574.2003 RX PUBMED; 12496214. RA Kutty G., Kovacs J.A.; RT "A single-copy gene encodes Kex1, a serine endoprotease of Pneumocystis RT jiroveci"; RL Infect. Immun. 71(1):571-574(2003). XX RN [2] RP 1-5609 RA Kutty G.K., Kovacs J.A.; RT ; RL Submitted (11-JUL-2002) to the EMBL/GenBank/DDBJ databases. RL CCMD, NIH, 10 Center Drive, MSC 1662, Bethesda, MD 20892-1662, USA XX FH Key Location/Qualifiers FH FT source 1..5609 FT /organism="Pneumocystis jirovecii" FT /mol_type="genomic DNA" FT /note="forma_specialis: hominis" FT /db_xref="taxon:42068" FT misc_feature complement(<1..238) FT /note="similar to C-3 sterol dehydrogenase/C-4 FT decarboxylase of Candida albicans deposited in GenBank FT Accession Number AAK69617" FT mRNA join(<536..1015,1061..1115,1164..1243,1287..1440, FT 1484..1863,1909..2012,2056..2526,2570..2898,2961..>3247) FT /gene="Kex1" FT /product="serine endoprotease Kex1" FT CDS join(536..1015,1061..1115,1164..1243,1287..1440,1484..1863, FT 1909..2012,2056..2526,2570..2898,2961..3247) FT /codon_start=1 FT /gene="Kex1" FT /product="serine endoprotease Kex1" FT /note="similar to Kex2 of Saccharomyces cerevisiae" FT /db_xref="GOA:Q8J0A2" FT /db_xref="HSSP:1OT5" FT /db_xref="InterPro:IPR015500" FT /db_xref="UniProtKB/TrEMBL:Q8J0A2" FT /protein_id="AAN12365.1" FT /translation="MMVYNKALHIFFLYWVLFIRILGASGSRDYDNRHYYVFHFSKKVD FT LKAFSDDLGFKYEKALENLEDHYLFSISKEFLEEEVERKVSEYFSGSEDGIVESFEDKV FT LFYQKQHLKRRYRKTPPVNYEDSLDTGHVPVRVAELEQIKQTLDIKDPIFGDQWHLYNL FT KDKFNDINVTSVWKQGITGKNVTVAIIDDGLDMTSEDLKDNYYPEGSYDFNDHNPVPMP FT KLPEDTHGTRCAGEVAAVRNTVCGIGVAYESKVSGLRILSGPITDLDEAESLNYDFHKN FT HIYSCSWGPDDDGKTVDGPSSLVLRALINGVNNGRNGLGSIYVFASGNGGIYEDNCNFD FT GYANSVFTITIGGIDKHGKRLKYSEACSSQLAVTYAGGSAGYIYTTDVGTNKCTSRHGG FT TSAAAPLAAGILALVLSVRPKLTWRDLQALIRISAVPVNLHEYGWEKTHSGLLFHDFYG FT YGKLDASLIIENAKKFKHLKPQARFSSRKETVNKIFSKNNGTITSKILIDSKSVKSANL FT GNLEHLIITVNIVHSKRGDLEVFIISPNGVTSRLASRRVYDFNSVGILNWNFVSVKHWG FT ESFLGNWTIRVNDKNNPNVDGSFMDWQIHLWGEAIDPKKAKPIPYPVVFTSNKTSNQTS FT ATSTSRPTATSSSTSKTTSATATKTSATETTPTSGTEHPTSPDKTKTQKGSWGRKAWLY FT FIVTFLILAFISALCYIYFQRRSRIKQSLIEESYEFEVLRDDEEDINYLFQDSEKAKIL FT QENPEIYTAFDIHDDFDSASTSFRRE" FT mRNA join(<3453..3464,3516..3544,3596..3697,3759..4048, FT 4101..>4651) FT /gene="trr1" FT /product="thioredoxin reductase Trr1" FT CDS join(3453..3464,3516..3544,3596..3697,3759..4048, FT 4101..4651) FT /codon_start=1 FT /gene="trr1" FT /product="thioredoxin reductase Trr1" FT /note="similar to Trr1 of Saccharomyces cerevisiae" FT /db_xref="GOA:Q8J0U0" FT /db_xref="HSSP:1VDC" FT /db_xref="InterPro:IPR005982" FT /db_xref="UniProtKB/Swiss-Prot:Q8J0U0" FT /protein_id="AAN12366.1" FT /translation="MHSKVIIIGSGPAGHTAAIYLARAELKPVLYEGMLANGIAAGGQL FT TTTTDVENYPGFPDGIMGPLLMEKFREQSVKYGTCIITETVSKLDLSKRPFKYWCESDE FT NTCHTADVVVMATGAYARRLHIPGEETYWQRGISACAVCDGAAPIFRGKCLSVVGGGDS FT AAEESLFLTRYATKVYLLVRRDKLRASAVMAKRLLNHPKIEVIWNTVVLRSLGDGHLLN FT RLEIKNVKTQVVSELHVSGLFYAIGHEPATALVRGQVECDDNGYIITKNGGPETNIKGF FT FAAGDVQDKKWRQAVTSAGSGCMAGLAAERLLAEEEEMKNIEKNKK" FT misc_feature complement(4695..>5609) FT /note="similar to conserved hypothetical protein of FT Schizosaccharomyces pombe deposited in NP_596742" XX SQ Sequence 5609 BP; 1895 A; 727 C; 1001 G; 1986 T; 0 other; tttttttttc aagaccatga attgagcttg ccatatgaaa aattacgtcc ggacgatgca 60 aatgtatcac ttctctcaag tactttggat cacagatgtc tccttggaag taatttactg 120 atgtaaacgc tttatttttc acatttaagt caaaaactgc tatttttttg catgtttttt 180 gcttaacaag ctgtgaagta agagataacc cgagaaaacc acatccccct ataaaaatgt 240 gtcagaatac gttaaaataa tccattcttc ataaaatatt acctataata agaggatatt 300 ccatcataaa atatttattt gtcgttgcca aagctcaaac tttaatcgat gttaactcgt 360 gatagactct actaacgttc ataaattttc ggatgaagaa aaattgtatt tattgaattt 420 ttgggggtat ttttaataat aactaaatat gtttttacta aaaacaataa tagatattat 480 acgggttatt taaatattta aaagcgtttt tatttaaggg tttttgtatt tttttatgat 540 ggtttataac aaagcattac atatattttt tctctattgg gttctattta taaggatatt 600 aggggctagt ggaagtaggg attatgataa taggcattac tatgtttttc atttttcaaa 660 aaaagtggat cttaaggctt tttcagatga tttagggttt aaatatgaaa aagcattaga 720 gaatctagaa gatcattatt tattttcaat atctaaggag tttttagaag aggaagttga 780 aagaaaagta tcagaatatt tttctggttc ggaagatgga atagtagaat catttgaaga 840 caaagttctt ttttatcaga aacagcactt gaaaagacgt tataggaaaa cgccgcctgt 900 aaattatgag gattctctag atacaggtca tgttccagtt agggtagctg agttggaaca 960 aattaaacag actttagata taaaagatcc gatttttggt gatcaatggc acttagtaag 1020 ttttttttct tatcttttat aaaaatttaa caatagtcag tataatctta aggataaatt 1080 taatgatata aatgtgacta gtgtttggaa gcaaggttga ttatatgagt gaacaatcgt 1140 ataaacgttt atcatgatct tagggattac gggaaagaat gtaaccgttg ctattataga 1200 tgatgggttg gatatgacta gtgaagactt aaaagataat tatgtataga aattgttgta 1260 aattttttat tttaattatt tttcagtatc ctgaaggctc ttatgacttt aatgatcaca 1320 accctgttcc aatgcctaaa cttcctgaag atacgcatgg gactagatgt gctggtgaag 1380 tagctgccgt tcgaaatact gtttgtggaa tcggtgttgc atatgaatcc aaagtttctg 1440 gtattttatt ctttttgact gaatctaata taatatcatt aaggtttgcg aatattatcc 1500 gggcctataa cagatcttga tgaagcagaa tcgcttaatt atgatttcca taaaaatcat 1560 atttattcct gtagttgggg acctgacgat gatggaaaaa ctgttgatgg gccttcttct 1620 cttgttctta gagcacttat taatggagta aataatggaa ggaatgggtt gggttctatc 1680 tatgtttttg catcaggaaa tggtggaata tatgaagata actgtaattt cgatggatat 1740 gcaaatagtg tgtttaccat tactattggt ggcatagata aacatggaaa gcgtcttaaa 1800 tattctgaag cgtgttcttc tcagctagct gttacatatg caggtggaag tgcgggatat 1860 attgtaactt taattctatt tttttttata taaatttata ataattagta tactactgat 1920 gttggtacaa ataaatgtac gagtagacat ggtggtacct ctgctgctgc acctcttgct 1980 gctggtattc ttgctttggt tctttctgta cggcaagtat tctattaaaa ttaagccttg 2040 attaataaaa actagaccta aacttacatg gcgcgatttg caagctctga taaggataag 2100 tgctgttccg gttaaccttc acgaatatgg atgggaaaaa acgcattctg ggcttttatt 2160 tcatgatttt tatggttatg gaaaattaga tgcatctctg ataattgaaa atgctaaaaa 2220 atttaaacat ttgaagcctc aagcaagatt ttcatctcgt aaagaaactg ttaataaaat 2280 attttctaaa aataatggga ctattacaag taaaattttg attgatagta aatctgttaa 2340 atcagctaat cttggaaatt tggaacactt aatcattact gtaaatattg ttcattctaa 2400 acgaggagat ttagaggtat tcattattag ccctaatggt gttacttcaa gacttgcatc 2460 tagacgtgta tatgatttta atagtgttgg aatacttaat tggaattttg tgtcagtaaa 2520 acactggtat ttttttttat agaaaaagag ctaaggtaat atttcttagg ggagaaagtt 2580 ttttaggtaa ttggactatt cgagttaatg ataaaaataa tccgaatgtt gatgggagtt 2640 ttatggattg gcagattcat ttgtggggtg aggcaattga tccaaagaaa gctaagccta 2700 ttccatatcc tgtcgtattt actagtaaca aaacttctaa tcaaacttct gcaacttcga 2760 catctagacc tacagctact tctagctcta cttcaaagac aaccagtgcg actgctacaa 2820 aaacatctgc tactgagact acacctacta gtggtactga acatcctact agtcccgata 2880 aaacaaaaac acaaaaaggt aaagacaata tgaaaatact aatttattta tcattacact 2940 ttatctaact tgtacaatag gatcttgggg gagaaaagct tggctatatt ttattgttac 3000 ttttcttatt cttgctttta tttcagcttt atgttatatt tacttccaac gacgctctag 3060 aataaagcaa tcgttaattg aagaaagcta tgaatttgaa gttcttagag atgatgaaga 3120 agatataaat tatttatttc aagattctga aaaagcaaaa atattacaag aaaatcctga 3180 gatatatact gcatttgata ttcatgatga ttttgacagt gcatctacca gttttagaag 3240 ggaataaata agctctagaa ctgttatatc tattctaatt tattatatta tttaataata 3300 atcttttgta ttttttatta ctctcttttt ccttcgatct acttgttaat ctctctagat 3360 caacgtcaaa aaatagagaa agtataaaat tgaagaaaag agcctttaat agatactttt 3420 ttgatagttt tttacatttt tttaagaaaa aaatgcattc aaaagtaata tctatcttca 3480 tttatccaca actttaattt tattaacata aaaaggtaat aattattgga tcaggcccag 3540 cagggtgtgt ttagttttta tggccttaat ttctcagtta ttaatgatat attagtcata 3600 ctgcagctat ttatcttgca agagctgaat taaaacctgt tttatatgaa ggaatgttag 3660 caaatggtat tgcagcaggt ggacaattaa caacaacgta tgtgtttata taagaggttt 3720 atagatatag aaaaagtata ttaatatact atacacagga ctgatgttga aaattatcct 3780 ggatttcctg atggcattat ggggccttta ttaatggaga agttccggga acaatcagta 3840 aagtatggga catgtattat aacagaaaca gtatcaaagc ttgatttatc aaaacgccct 3900 tttaaatatt ggtgtgaatc tgatgaaaat acatgtcata cggcagatgt agttgtgatg 3960 gcaactgggg cgtatgctcg acgattacat attccaggtg aagagacata ttggcagcgc 4020 ggaatttcag cctgtgctgt atgtgatggt actaaattag aaaggattat gtgtatcttt 4080 atggttgatt atatatttag gggcagcacc aatatttcga ggaaaatgtc tttcagtcgt 4140 aggaggtgga gattctgctg cagaagaatc gttattttta acgagatatg caactaaagt 4200 atatctactt gttaggaggg acaaattaag ggcttcagca gttatggcta aaagattact 4260 taatcatcct aaaattgaag ttatctggaa tacagtagtg ttacggtcac tcggtgatgg 4320 tcatttgtta aatcgtttgg aaattaaaaa tgttaaaacg caagttgttt cagaattaca 4380 tgttagtggt ctcttttatg caattggtca tgaaccagca acggctttag ttcgaggtca 4440 agttgaatgt gatgataatg gatatattat tacgaagaat ggtggccctg aaacaaatat 4500 taagggattt tttgcagcag gtgatgttca agacaaaaag tggcgacaag cagttacgtc 4560 tgcgggcagt ggatgtatgg caggacttgc agctgaacga ttattagcag aagaggaaga 4620 aatgaaaaat atagaaaaaa ataagaaata gttgagatgt ttttatgtaa ttttaaaatt 4680 aatttttttg tgttaactgt ccatgtattt ttttcatttt tgtagcataa ttaatatctt 4740 tttctttctg tattttttca gtttcacgag ctataaattg agcatctcgt ctaagcattc 4800 taatagcact tcttttatta tcacgatatt ggaacttcaa ttttgcagat tcagctcgtt 4860 cgcggtctgg atcatatgat ttcttgtcaa gagaatattc actttcaaat ttaggaataa 4920 aactttgaat tggaataggt ttatgtgctt gcaacattaa tggtttacgt gactgaagtg 4980 aaaaatgaag taattttgta atccgttcat ttatagaatt tatctcagtc taaatagtta 5040 aaaaatacag atctaataaa atagtttaat ttacctgaag ttcagaagac aaaggaattt 5100 tactagagaa taattttagt aaaattaaac aaggtgaaaa gatttctatg aatgcaagtt 5160 ttccattcca caaattagca taataatcaa ttaattgagc agctgtccta aaaagagaaa 5220 tttctaattc tttattttca ttatcattag aatatatatc tgaaattttc aaagttctcg 5280 gtttacatga taaatcaaaa aacttatttt ctgaattaat agattttttt ttgtctaact 5340 tttttttatt tttttgaaac aaaatcttta ttatattcaa cagtgcatgt attacttcag 5400 gaactactcg tcgtgacaaa ttaatatact aataaaatta aaaataataa ttataaaaaa 5460 taaaaaaaac ctctgcaaac aatgttatga cataaagttt taaactaata tctcctaatg 5520 atacaatttt taattgagaa agaagctggc ccattataag taatgtcgga gtaactatta 5580 catgagaaag gtcggaagtt ggaaaaatg 5609 // |
|