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EBI DbfetchID AY061649; SV 1; linear; genomic DNA; STD; PRO; 23166 BP. XX AC AY061649; XX DT 20-AUG-2002 (Rel. 72, Created) DT 16-APR-2005 (Rel. 83, Last updated, Version 3) XX DE Streptococcus thermophilus strain MR-2C exopolysaccharide synthesis gene DE cluster, complete sequence. XX KW . XX OS Streptococcus thermophilus OC Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus. XX RN [1] RP 1-23166 RX PUBMED; 12647947. RA Broadbent J.R., McMahon D.J., Welker D.L., Oberg C.J., Moineau S.; RT "Biochemistry, genetics, and applications of exopolysaccharide production RT in Streptococcus thermophilus: a review"; RL J. Dairy Sci. 86(2):407-423(2003). XX RN [2] RP 1-23166 RA Welker D.L., Broadbent J.R.; RT ; RL Submitted (01-NOV-2001) to the EMBL/GenBank/DDBJ databases. RL Biology, Utah State University, 5305 Old Main Hill, Logan, UT 84322-5305, RL USA XX FH Key Location/Qualifiers FH FT source 1..23166 FT /organism="Streptococcus thermophilus" FT /strain="MR-2C" FT /mol_type="genomic DNA" FT /db_xref="taxon:1308" FT misc_feature 1..181 FT /note="deoD; similar to purine nucleotide phosphorylase" FT CDS 527..1969 FT /codon_start=1 FT /transl_table=11 FT /gene="wzg" FT /product="CspA" FT /function="putative involvement in exopolysaccharide gene FT regulation" FT /db_xref="GOA:Q8KQS8" FT /db_xref="InterPro:IPR004190" FT /db_xref="InterPro:IPR004474" FT /db_xref="UniProtKB/TrEMBL:Q8KQS8" FT /protein_id="AAL32494.1" FT /translation="MSSRTNRKQKHTSNGSWGMVNVGLTILYAILALVLLFTMFNYNFL FT SFRFLNIIITIGLLVVLAISIFLQKTKKLPLVTTVVLVIFSLVSLVGIFGFKQMIDITN FT RMNQTAAFSEVEMSIVVPKESDIKDVSQLTSVQAPTKVDKNNIEILMSALKKDKKVDDV FT ASYQEAYDNLKSGKSKAMVLSGSYASLLESVDSNYASNLKTIYTYKIKKKNSNSANQVD FT SRVFNIYISGIDTYGPISTVSRSDVNIIMTVNMNTHKILLTTTPRDAYVKIPGGGADQY FT DKLTHAGIYGVETSEQTLEDLYGIKLDYYARINFTSFLKLIDQLGGVTVHNDQAFTQEK FT FDFPVGDIQMNSEQALGFVRERYNLDGGDNDRGKNQEKVISAILNKLASLKSVSNFTSI FT VNNLQDSVQTNMSLNTINALANTQLESGSKFTVTSQAVTGTGSTGQLISYAMPNSSLYM FT MKLDNSSVESASQAIKKLMEEK" FT CDS 1970..2701 FT /codon_start=1 FT /transl_table=11 FT /gene="wzh" FT /product="wzh" FT /function="putative involvement in exopolysaccharide FT synthesis" FT /db_xref="GOA:Q56039" FT /db_xref="InterPro:IPR004013" FT /db_xref="InterPro:IPR016667" FT /db_xref="UniProtKB/TrEMBL:Q56039" FT /protein_id="AAL32495.1" FT /translation="MIDVHSHIVFDVDDGPETLEESLDLIGESYAQGVRKIVSTSHRRK FT GMFETPEDKIFANFKKVKAEAEALYPDLTIYYGGELYYTSDIVEKLEKNLIPRMHNTQF FT ALIEFSARTSWKEIHSGLSNVLRAGVTPIVAHIERYDALEENADRVREIINMGCYTQVN FT SSHVLKPKLFGDKDKVRKKRVRFFLEKNLVHMVASDMHNLGPRPPFMKDAYEIVKKNYG FT SKRAKNLFIENPKTLLENQYL" FT CDS 2710..3402 FT /codon_start=1 FT /transl_table=11 FT /gene="wzd" FT /product="wzd" FT /function="putative involvement in exopolysaccharide chain FT length determination" FT /db_xref="GOA:Q8VM10" FT /db_xref="InterPro:IPR003856" FT /db_xref="InterPro:IPR005701" FT /db_xref="UniProtKB/TrEMBL:Q8VM10" FT /protein_id="AAL32496.1" FT /translation="MNQDNTKSDEIDVLALLHKLWTKKLLILFTAFYFAVFSFLGTYFF FT IQPTYTSTTRIYVVNQATDNKNLSAQDLQAGTYLANDYKEIITSNDVLSEVIKDEKLNL FT SEAELSKMVSVNIPTDTRLISISVNAKTGQDAQTLANKVREVASKKIKKVTKVEDVTTL FT EEAKLPESPSSPNIKLNVLLGAVLGGFLAVVGVLVREILDDRVRRPEDVEDALGMTLLG FT IVPDTDKI" FT CDS 3412..4161 FT /codon_start=1 FT /transl_table=11 FT /gene="wze" FT /product="wze" FT /function="putative involvement in membrane translocation FT of the exopolysaccharide" FT /db_xref="GOA:Q8KHR2" FT /db_xref="InterPro:IPR005702" FT /db_xref="UniProtKB/TrEMBL:Q8KHR2" FT /protein_id="AAL32497.1" FT /translation="MPLLKLVKSKVDFAKKTEEYYNAIRTNIQFSGAQMKVIAISSVEA FT GEGKSTISVNLAISFASVGLRTLLIDAETRNSVLSGTFKSNEPYKGLSNFLSGNADLNE FT TICQTDISGLDVIASGPVPPNPTSLLQNDNFRHLMEVARSCYDYVIIDTPPVGLVIDAV FT IIAHQADASLLVTEAGKIKRRFVTKAVEQLVESGSQFLGVVLNKVDMTVDKYGFYGSYG FT SYGEYGKKSDQKEGHSRAHRRRKVGWN" FT CDS 4214..4897 FT /codon_start=1 FT /transl_table=11 FT /gene="cpsE" FT /product="putative phosphogalactosyltransferase CpsE" FT /db_xref="GOA:Q56042" FT /db_xref="InterPro:IPR003362" FT /db_xref="UniProtKB/TrEMBL:Q56042" FT /protein_id="AAL32498.1" FT /translation="MSQAKEEISDVMTYSELTSHKPKIIYSLIKRIGDILVSSIGLIIL FT IPLFLIVALIMKCSEPTAPIFFSHIRNGKNGKKFKMYKFRTMCQDAESILMKDTELFAK FT FKANGYKLETHEDPRITKIGGILRKTSIDELPQLINVFLGQMSLVGPRPLPDREIIEYG FT DNQEKFLSVKPGMTGWWQVSGRSTIGYPERCHLELYYVEKCCFTFDVLILLKTIGIVLK FT RVGAR" FT misc_feature 4906..5055 FT /note="orfgt1p; similar to MR-1C CpsF" FT CDS 5061..6020 FT /codon_start=1 FT /transl_table=11 FT /gene="cpsF" FT /product="putative glycosyltransferase CpsF" FT /db_xref="GOA:Q56043" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q56043" FT /protein_id="AAL32499.1" FT /translation="MNEQVTFILCDFLVREIKPKYDLLAYQFISKKIKEIKPDIVHCHS FT SKAGVIGRLAAKRRGVKKIFYTPHAYSFLAPEFSGKKKFLFVQIEKFLSRFATTKIFCV FT SIAEMQAALEVNLDKTDKFQVIYNGLPEIDLPSKETIRAQLGLEKAAVVIGNNAKMSEQ FT KNPMFFMEIARKMIRQNANWHFVWVGDGQLMPLFQSFIKQNGLEGNIHLLGERPDSEIV FT VTAYDIFLTTSQYEGLPYAPIEAMRAGVPILATKVVGNSELVIEGKNGYLIDLEWSKSV FT EEKLYKAAKIDAQMIKADFRQRFAIDQILKQIETIYLA" FT misc_feature 6061..6312 FT /note="orfgm1p; similar to Streptococcus pneumoniae FT UDP-galactopyranose mutase" FT CDS 6552..7706 FT /codon_start=1 FT /transl_table=11 FT /gene="cpsG" FT /product="putative glycosyltransferase CpsG" FT /db_xref="GOA:Q8KIC9" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q8KIC9" FT /protein_id="AAL32500.1" FT /translation="MECKLSNGEENNMKKISILHFSQVSGGGVEKYIKLFLKYSDVTKF FT NNYLVAPNLENYDEFNGYLKMSVNFNMEQTFSPLKIFKNVFFIRSVLKKINPDIVYLHS FT TFAGVVGRIASIGLPTKVVYNPHGWSFKMDNSYLKKLIFKLIEFSLSFLTDKFILISES FT EYILANHISFNKSKFSLINNGVEVITGDSRNEIEEIFPNEDFIIGMVGRLSPPKEFFFF FT IDFAKKILQIRNDTNFIIVGDGELRSEIERMILDNGLGDKIYITGWVDNPRNYIEKFDQ FT AILFSRWEGLSLTIAEYMSQKKTILATNIGGINDLITDGETGMLIEVGDLNSAVSKSFE FT LRNNKEVSNQLANNAYNKVVEQFSIEKQMAEIESLFIEMCNNEK" FT misc_feature 7707..7877 FT /note="orfgt2p; similar to Sfi6 CpsF" FT CDS 7899..8378 FT /codon_start=1 FT /transl_table=11 FT /gene="cpsH" FT /product="CpsH" FT /function="putative involvement in sugar biosynthesis" FT /db_xref="GOA:Q56045" FT /db_xref="HSSP:1KRR" FT /db_xref="InterPro:IPR001451" FT /db_xref="InterPro:IPR011004" FT /db_xref="InterPro:IPR018357" FT /db_xref="UniProtKB/TrEMBL:Q56045" FT /protein_id="AAL32501.1" FT /translation="MLILKLKFHLKSLFLKWIYRLLYLKKFQFGARLTFRDGFHLLIEK FT SGKVIIGNHVFFNNFCSINAMLSVTIGDDCIFGENVKIYDHNHCYQNKSQPISKQGFST FT AAIQIGRNCWIGSQVTILKGVTIGDNSIIGAGVVVYQDVPENSIVLSNGEIRKRG" FT CDS 8384..9358 FT /codon_start=1 FT /transl_table=11 FT /gene="cpsI" FT /product="putative glycosyltransferase CpsI" FT /db_xref="GOA:Q56046" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q56046" FT /protein_id="AAL32502.1" FT /translation="MYLKSLISIVIPVYNVEKYLEKCLQSVQNQTYNNFEVILVNDGST FT DSSLSICEKFVNQDKRFSVFSKENGGMSSARNFGIKKAKGSFITFVDSDDYIVKDYLSH FT LVAGIKSETSIVCSKFFLVDEKGSLLTKKEAPKKKSEVVSIEESIKILLLQQNGYDLAV FT WGKLYPVSFFETISFPEGKLYEDMGTTYKLLKLASEVVFLDAYDYAYVQRPNSIMNSSF FT NLKKLDIIEMVHEMENDILAQFPNLALYVKNRAFAAEVKIFLEIPKEKEFEQAQKQLWH FT DIKKNRKAPFMTKGARLKNRLGASLSFLGKSLFLTIGKQLVDR" FT CDS 9448..10530 FT /codon_start=1 FT /transl_table=11 FT /gene="wzy" FT /product="wzy" FT /function="putative involvement in exopolysaccharide FT polymerization" FT /db_xref="UniProtKB/TrEMBL:Q56047" FT /protein_id="AAL32503.1" FT /translation="MVIYFLLFPMIAMIYLMTLLLRQKAQIQKTIFCVLTFGTLGFISA FT SRASSVGTDVTLYENIFKSINYGISAENNWGYVIYNKLIGSVFGYTGHEITAANSVLIT FT ILIGIFIWKVAEHYFVATFLYISLFYYATSFNISRQFIAMGLVLVAISFALDKKVMPWF FT ILTVLATLFHATAIVAFPVYWLTKVHWDVKKTLSIFPITIFASFIFDAILNIFVRFFPH FT YEMYITGTQFNISDQGQGRVVLVKIFILLILFTLFLFYKKSYALISECHQSLIALTTVG FT LSIGIVFYNNILLNRIEMFYSILSIVFIPIAIDYISLKFKQKDAVRLMLTIGILLITLV FT PYYIQVSGNYSGILPYVIQQ" FT CDS 10555..11505 FT /codon_start=1 FT /transl_table=11 FT /gene="cpsK" FT /product="CpsK" FT /function="putative involvement in exopolysaccharide FT membrane translocation" FT /db_xref="GOA:Q8KHW5" FT /db_xref="InterPro:IPR003406" FT /db_xref="UniProtKB/TrEMBL:Q8KHW5" FT /protein_id="AAL32504.1" FT /translation="MEDRKKQAILILSHRNTLALKSTIELLDSQYFDFFLHIDKKSRIQ FT DFFYLKKITKFSTIHFSERKNVHWGGFSMVEAMFALLECARDTGEYSYFHFLSGDDMPI FT KDNEIVFNFFENSYPKNFIDILDFENVNKNSYFYEPPEMIEERVKYYYPHMDILNRKGT FT NFIGKKLIYLQKLLKVNRLKNREIEIFKGHQWCSLTNQFVDILLDKEERRVGKSYFSSS FT LIPDECYFQTFAMIKKVEIYQQKNMSARLIDWTRGKPYIWRQDDFFEIMNDKDSMFSRK FT FDENVDRKIIEEIYIKIRGRSTDEANKIKDKRFTK" FT CDS 11465..12388 FT /codon_start=1 FT /transl_table=11 FT /gene="cpsL" FT /product="CpsL" FT /function="putative involvement in exopolysaccharide FT synthesis" FT /db_xref="GOA:Q56049" FT /db_xref="InterPro:IPR007345" FT /db_xref="UniProtKB/TrEMBL:Q56049" FT /protein_id="AAL32505.1" FT /translation="MKQIKSKIRDLQNNFTYVFGKKTFLGRGEAIIIDEPEHGNLGDQA FT IAFAENQFLVNHVSVRDVEHLIESKTISEIKSIKKNIGKKELVFFHGGGNFGTLYLKYE FT RIRRLAVSKLPFNKMILFPQSISFEDSRFGQKQLNKSKKIYSQNTNFILTAREPKSYGL FT MKKCFPYNKVILTPDIVLSFKFEVTISDTHIGKEKDSVITYENRQHYLEIKWDEIAQHE FT VALTDRLHGMIFSYITGTPCVVLANNNHKIEGTYKHWLNEVNYIRFIENPTVENILDAI FT NDLKQIEPHYIDLSDKFQPLIDAIKG" FT CDS 12396..13817 FT /codon_start=1 FT /transl_table=11 FT /gene="wzx" FT /product="wzx" FT /function="putative involvement in exopolysaccharide FT synthesis" FT /db_xref="GOA:Q8KQS7" FT /db_xref="InterPro:IPR002797" FT /db_xref="UniProtKB/TrEMBL:Q8KQS7" FT /protein_id="AAL32506.1" FT /translation="MNKYKKLLSNSLVFTIGNLGSKLLVFLLVPLYTYAMTPQEYGMAD FT LYQTTANLLLPLITMNVFDATLRFAMEKSMTKESVLTNSLVVWCFSAVFTCLGACIIYA FT LNLSNKWYLALLLTFNLFQGGQSILSQYARGIGKSKIFAAGGVILTFLTGALNILFLVY FT LPLGITGYLMSLVLANVGTILFFAGTLSIWKEISFKIIDKKLIWQMLYYALPLIPSSIL FT WWLLNASSRYFVLFFLGAGANGLLAVATKIPSIISIFNTIFTQAWQISAIEEYDSHQKS FT KYYSDVFHYLATFLLLGTSAFMIVLKPIVEKVVSSDYASSWQYVPFFMLSMLFSSFSDF FT FGTNYIAAKQTKGVFMTSIYGTIVCVLLQVVLLPIIGLDGAGLSAMLGFLTTFLLRVKD FT TQKFVVIQIKWRILISNLLIVLAQILCLFYLPSEFLYFGLALLFCGMLVVNQRTILYII FT MALKIKNKTFGMKSS" FT repeat_region 13853..14580 FT /mobile_element="insertion sequence:ORF14.9" FT misc_feature 13893..14468 FT /note="similar to transposase" FT repeat_region 14581..15396 FT /mobile_element="insertion sequence:ISS1SA" FT repeat_region 14581..14598 FT /rpt_type=INVERTED FT misc_feature 14804..15319 FT /note="similar to transposase" FT repeat_region 15379..15396 FT /rpt_type=INVERTED FT CDS complement(15511..16569) FT /codon_start=1 FT /transl_table=11 FT /gene="cpsO" FT /product="putative glycosyltransferase CpsO" FT /db_xref="GOA:Q8KHK5" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q8KHK5" FT /protein_id="AAL32507.1" FT /translation="MKVLIIYPHLTGKGGTETVLAKVLTASDESFNFSLFLPGGCSDQR FT WMQAFADRVTLHSKTNSFTRFWDTLVFILKTQPNIVISMSKVQILAAWMARKIFRRKFK FT LVSWNHFSLLETRFPSMLKLFKLCDYHLAISSGIQHQLQGLGISPNRIFLVYNPIDPQE FT KLIPRTNGHTKEFVYIGRLQSKSQKNLTELISILGATTAYPWHLRVIGAGDDDDEATLK FT RQAKDAGIAERITWLGWQSQPWDILDEDEVDLLFLTSKFEGLPMVLAEAMSYGVPCFSA FT DCPTGPEDIIKDGANGTLYTPGNVTQAHEKLVDFFEKKTTYLSPEEVKMTITKMYTQQY FT LATLKQLLIDIQ" FT repeat_region 16910..16914 FT /rpt_type=DIRECT FT repeat_region 16915..18232 FT /mobile_element="insertion sequence:IS1191" FT repeat_region 16915..16946 FT /rpt_type=INVERTED FT misc_feature 17008..18183 FT /note="similar to transposase" FT repeat_region 18204..18232 FT /rpt_type=INVERTED FT misc_feature 18218..18409 FT /note="orfN; similar to Streptococcus thermophilus NCFB2393 FT eps gene cluster orfN" FT repeat_region 18233..18237 FT /rpt_type=DIRECT FT misc_feature 18403..18801 FT /note="orfcof1; similar to Streptococcus pneumoniae cof FT family protein found in Genbank Accession Number AE007441" FT misc_feature 18819..18839 FT /note="orfpgm1; similar to phosphoglycerate mutase" FT misc_feature 18840..19412 FT /note="orfpgm2; similar to phosphoglycerate mutase" FT CDS 19491..20627 FT /codon_start=1 FT /transl_table=11 FT /gene="cpsX" FT /product="CpsX" FT /function="putative involvement in membrane translocation FT of the exopolysaccharide" FT /db_xref="InterPro:IPR002549" FT /db_xref="UniProtKB/TrEMBL:Q8KHY7" FT /protein_id="AAL32508.1" FT /translation="MKFTKNQFIWLVVLFFSCFLIYTYWETVVSICNKIFVASQPFLFG FT AGIAFVVNILMSFYEKILIKFIPFGFITKIKRPVSLLLAFATIGLIFTWVVFTVLPDLI FT DSINTLISQDRSAINNLINWLLKNKSLQKIIQDLGGVTQVRELINSYSAQLLQQIMNGL FT TNFLTSLTSLPSTLINLFISIVFSCYVLVGKEKLGSQVNRLVDVYLGRYGKTFHYVVAI FT LNNRFHNFFVYQSIEACILGTLCYIGMRIFNFPYAATISILIGFSAMIPVLGAYIGVTI FT GTILIMTHSVTLALLFVAYVVILQQFEGNLIYPYVVGGSTGLPVVWVILAITIGSALGG FT ILGMLVSVPVAATLYQIVKDNVVTREKAKAVASLENSD" FT misc_feature 20750..22139 FT /note="orfbg1; orfbg2; orfbg3; orfbg4; orfbg5; orfbg6; FT similar to Streptococcus mutans beta-glucosidase found in FT GenBank Accession Number AF206272" FT misc_feature 22348..22671 FT /note="orfhp; similar to Clostridium acetobutylicum FT hypothetical protein found in GenBank Accession Number FT AE007517" FT misc_feature 22689..23165 FT /note="orfABC; similar to ABC transporter" XX SQ Sequence 23166 BP; 7530 A; 3631 C; 4483 G; 7522 T; 0 other; tgtcgaaatg gaagcagcag cactttacta ccttgcagcc caacaccaag tagatgctct 60 ggctattatg actatttctg atagtttggt aaatccagat gaggacacaa cagctgagga 120 acgtcaaaat actttcactg atatgatgaa agttggtctt gaaacactaa ttgcagacta 180 gtttgtaaaa ggacgccatt tggtcgtcct tttgtgttgt agctaatatc tgttcgaagt 240 gataataagt taaaattttt caaactacta gaaaaaataa aaatatttgg aagaagaaga 300 cttataataa ataggtaaat atctgacaat ttaaagttta actactaaaa atgtaaaaga 360 tagttcacaa tataatggaa aatgatataa attaaatgat tgatatcata atgaaaaacg 420 ttttcttatt tttttgaaaa aagaatgaca attgaaatga ggttgtatta atgttataat 480 aataataatg gggaatacct aattttaatt tttaggagca atttatatga gttcgcgtac 540 gaatcgtaag caaaagcata cgagtaatgg atcgtggggg atggtcaacg ttgggttgac 600 catcctgtat gctattttag cattggtctt attattcacc atgttcaatt ataatttcct 660 atcctttagg tttttgaaca tcattatcac cattggtttg ttggtagttc ttgctattag 720 catcttcctt cagaagacta agaaattacc actagtgaca acggttgtac tggttatctt 780 ctcgctagtt tctctggttg gtatttttgg ttttaaacaa atgattgaca tcactaaccg 840 tatgaatcag acagcagcat tttctgaagt agaaatgagc atcgtggttc ctaaggaaag 900 tgacatcaaa gatgtgagcc agcttactag cgtacaggca cctactaagg ttgataagaa 960 caatatcgag atcttgatgt cagctctcaa aaaagataaa aaagttgatg atgttgcctc 1020 atatcaagaa gcttatgata atctcaagtc tggcaaatct aaagctatgg tcttgagtgg 1080 ctcttatgct agcctattag agtctgtcga tagtaattat gcttcaaatc taaaaacaat 1140 ttatacttat aaaattaaaa agaagaatag caactctgca aaccaagtag attcaagagt 1200 cttcaatatt tatattagtg gtattgatac ctacggtccg atttcaacag tgtcacgttc 1260 agatgtcaat atcattatga cagtaaacat gaatacacat aagattctct tgacgactac 1320 tccacgtgat gcatacgtta agattcctgg tggtggggca gaccagtatg ataaattaac 1380 ccacgcaggt atttatggcg ttgaaacatc tgaacaaact ctagaagatc tttatggtat 1440 taagcttgat tactatgcac gaattaactt cacatctttc cttaagttga ttgaccaact 1500 tggtggtgtg acagtccata atgatcaagc tttcacacaa gagaagtttg atttcccggt 1560 tggagatatc caaatgaatt cagagcaagc acttggattt gttcgtgaac gctataattt 1620 agatggcgga gataatgacc gtggtaaaaa ccaggagaaa gttatttctg cgattttaaa 1680 caagttggct tctctaaaat ctgtatcaaa ctttacttca atcgttaata atctccaaga 1740 ctctgtccaa acgaatatgt ctttgaatac cattaacgct ttggctaata cacaacttga 1800 atcaggttct aaatttacgg tgacttctca agcagtaaca ggtacaggtt caaccggaca 1860 attgatctct tatgcgatgc caaattctag tctttacatg atgaaactag ataattcgag 1920 tgtggaaagt gcctctcaag ctatcaaaaa attgatggag gaaaaataag tgattgacgt 1980 tcactcacat attgtttttg atgttgatga tggtcctgaa actttagaag aaagtttaga 2040 cctcattggt gaaagttacg cccagggggt acgtaagatt gtttcaacat cccatcgtcg 2100 taaggggatg tttgagactc cagaggataa aatttttgcc aactttaaaa aagtaaaagc 2160 agaagcagaa gcactttatc cagacttaac tatttattat ggaggtgaac tttattacac 2220 ctcagacatt gtggagaaac ttgaaaagaa tctcattccg cgcatgcaca acactcaatt 2280 tgctttaatt gagtttagtg ctcgcacatc ttggaaagaa attcatagtg ggcttagtaa 2340 tgttttgaga gcgggggtaa cgcctattgt tgctcatatt gagcgctatg atgccctcga 2400 agaaaatgct gaccgtgttc gagaaatcat caatatgggc tgctatactc aagtcaatag 2460 ctcacatgtc ctcaaaccaa agctctttgg agataaagat aaagtaagaa agaaacgtgt 2520 tcgctttttc ttggagaaaa atttggttca tatggttgct agcgacatgc ataatcttgg 2580 gccgagacca ccatttatga aagatgctta tgaaattgtt aaaaagaact acggctccaa 2640 acgtgctaag aatcttttta ttgaaaatcc caaaacatta ctagaaaatc aatatttata 2700 ggagatatta tgaatcaaga taacactaaa agtgatgaaa tcgacgtact agcattgcta 2760 cataaacttt ggacgaagaa gcttttgatt cttttcacag ctttttattt cgctgttttc 2820 agtttcttag gtacttattt ctttatccaa ccaacatata catcaacaac gcgtatctat 2880 gttgttaatc aggcaacaga taataagaat ctttctgctc aagatttgca agctggtacc 2940 tatttggcaa atgactataa agagattatt acatcaaatg atgtattatc agaagttatt 3000 aaagatgaaa aattgaattt gagtgaggca gaactgtcta aaatggtttc agttaatatt 3060 cctactgata ctcgtcttat ttcaatttct gttaatgcta aaactggtca agatgcgcaa 3120 acacttgcca ataaggttcg tgaagttgct tcaaaaaaaa tcaagaaggt gacaaaagtt 3180 gaagatgtca caacgctcga agaagctaaa ttgccagagt caccatcttc accaaatatc 3240 aaacttaatg tgcttcttgg ggcagtgctt ggaggattcc ttgcagtggt tggtgtattg 3300 gtacgtgaaa tcctagatga tcgtgttcgc cgtccagaag atgtggaaga tgcccttgga 3360 atgacacttc ttggaattgt ccctgataca gataaaattt aaggagaaga aatgccttta 3420 ttaaagttag ttaaatcaaa agtagacttt gctaaaaaga cggaagagta ttataacgct 3480 attcgcacaa atattcaatt ttctggtgct cagatgaaag tgattgcgat tagctctgtt 3540 gaagctggtg aaggaaaatc aacgatatct gttaacttgg cgatttcatt tgctagtgtt 3600 gggctccgaa cacttctgat tgatgcggaa acgcgtaatt ctgttttgtc aggtacattt 3660 aaatcaaatg agccttataa aggtctttca aatttccttt caggaaatgc cgatctaaat 3720 gaaacgattt gccaaactga tatttctggt ttagatgtta ttgcatctgg tcctgttcca 3780 cctaatccaa caagtctttt gcaaaatgat aattttagac atttgatgga agttgctcgt 3840 agttgttatg attatgtcat catcgataca ccaccagttg gtctggttat tgatgcagtt 3900 attattgccc atcaggctga tgccagtctt ttggttacag aagctgggaa aattaaacgt 3960 cgtttcgtaa ctaaggccgt tgaacaattg gtagaaagtg gttctcagtt cttaggggtc 4020 gtccttaata aagttgacat gacagttgat aaatatggat tttatggttc ttacggatca 4080 tatggcgagt atggaaaaaa atctgaccaa aaagaaggtc attcaagagc acatcgtcgt 4140 agaaaagtcg gttggaatta acgcgttagt gtgttttaag atgtcgttgg gaacgacaag 4200 tggagggaat gagatgtcac aagctaaaga ggaaatttca gatgttatga cttattcaga 4260 gctaacaagt cataagccca aaattattta tagcttgatt aagcggattg gtgatatttt 4320 ggttagttct attggtttaa ttattttgat accgctattt ttgatagttg ctttgatcat 4380 gaaatgctct gaaccaacag cacctatatt tttctcacat attagaaatg gtaaaaatgg 4440 caaaaagttc aaaatgtata aatttagaac catgtgtcag gacgcagaat cgattttgat 4500 gaaagatacg gaactttttg caaaatttaa ggcaaatggt tataaacttg aaacgcatga 4560 agatcctaga attacaaaaa tcggtggcat attaaggaaa acaagtattg atgaattgcc 4620 acaactgatt aatgtttttt taggacaaat gtcattagtg ggtccacgtc cactaccaga 4680 tagagaaatc attgaatacg gtgataacca agaaaaattt ttaagcgtta aaccaggcat 4740 gacaggatgg tggcaagttt cagggagaag tactattggg tatcctgagc ggtgtcatct 4800 tgagctttat tatgtagaaa agtgttgttt tactttcgat gttcttatat tacttaagac 4860 aattgggatt gttttgaaga gagttggagc gcgttagtac tgatgaaaca aaaattatta 4920 ttgataatag aagcgatgag tggtggagcc ggtcgtcatg tacaagactt gattagtcat 4980 ctacctcaag aaaaatttga tatttatgtg atttattcaa atcatagaac aaatcctgtt 5040 ttttggaaaa aatagtaacg atgaatgagc aagtaacttt tattttatgt gattttctcg 5100 taagagaaat taaaccgaaa tatgatttgc ttgcttatca atttatttct aaaaagatta 5160 aagaaatcaa accagatatt gtacattgtc acagttcaaa agctggtgtt attggtcgtt 5220 tagctgccaa aagacgaggt gttaaaaaaa tattttatac gccacatgct tattcgtttt 5280 tggcacctga atttagtggg aagaaaaagt ttctatttgt tcaaattgaa aagtttttaa 5340 gccgatttgc gacaactaag atattttgtg tgtcaatagc ggaaatgcaa gctgctcttg 5400 aagtaaatct agataaaacc gataagtttc aggtaattta taatggtttg ccagaaattg 5460 atttaccaag caaagaaacg attcgggcgc aattaggact ggaaaaggca gcagttgtta 5520 taggcaataa tgcaaaaatg tcggaacaga aaaatcctat gttttttatg gaaattgccc 5580 gaaaaatgat tagacaaaac gcaaattggc attttgtgtg ggtaggtgat ggtcagctga 5640 tgccactttt tcaatcattt attaagcaaa atggactaga gggaaatatc catttgcttg 5700 gcgagcgtcc tgatagtgaa atagttgtga cagcctatga catcttcttg acgacttccc 5760 aatatgaagg tttaccttat gcaccaattg aagcgatgcg agctggtgtc ccgattcttg 5820 cgacaaaagt tgttggcaat agtgagcttg tgatagaggg caaaaatggt tatttgattg 5880 acttagagtg gtcaaaatct gtcgaagaaa aattatataa ggcagcgaaa atagatgcac 5940 aaatgattaa agcagatttt aggcaaaggt ttgcgattga tcagatatta aagcaaattg 6000 aaacaattta tttagcttga atgaagaatg aggaggcata aatgctgatt ttgaaattaa 6060 aatttcatct taattggtac acaaacgaaa accattatta cacgtgagta ttcgaagacc 6120 tggaaacgag gcgatgagcc gtattatcca gtgaacaatg atcgtaacaa caaactctat 6180 actgcctata agcgtcttgc cgagcaacaa gagaatgtca ttttcggtgg acgtctaggt 6240 cactaccgtt actacgatat gcaccaggta attggagctg ccttgcagtg tgtcagaaat 6300 gaagtgaagt aaatcttgat gaagttgaat aactttaagt aattttatac ttaatccaat 6360 tgatgaaaat atttttgtat cgatttatct tctgtaagaa gagtcctaat cgtttaaaaa 6420 atgtacaatt gagtttttat atttttaaat aaagttactt ttaagtcgtg ttatagaata 6480 tacatgaata ggtgtattag aaaatttatt aatctaatcc tcgaaaataa ctgactgtaa 6540 ggaatcaagt tgtggagtgt aagttgtcaa atggagagga aaataatatg aaaaaaattt 6600 caattttaca cttttcccaa gtatcaggcg ggggagttga aaagtacata aaattatttt 6660 taaagtattc tgatgtgaca aaatttaata attatttagt tgcacctaat cttgaaaatt 6720 atgacgaatt taatggatat ttaaagatgt ctgtcaattt taatatggaa caaacttttt 6780 ctccgctaaa aatattcaaa aatgtctttt ttattcgtag tgtactcaaa aaaataaacc 6840 cagatatagt atacctacat agtacatttg caggtgtcgt aggtcgtatt gcttcaatag 6900 gtttgccaac aaaagtagta tacaatcctc acggatggtc cttcaaaatg gacaacagct 6960 atttgaaaaa gcttattttt aaattaatcg aattttcttt atctttttta actgataagt 7020 ttattttaat ttcggaatct gagtatattt tggctaacca tatttcattt aataaaagca 7080 agttttcact aattaataat ggtgttgaag tgattacagg ggattcaaga aatgagatag 7140 aagagatatt tccaaatgag gattttataa ttggcatggt tggcagacta agcccaccca 7200 aagagttttt cttttttatt gattttgcaa aaaaaatatt acaaattcga aacgatacca 7260 attttattat cgtgggtgat ggagagttac gaagtgaaat agaaagaatg atactagata 7320 atgggttagg agataaaatc tatattactg ggtgggttga taatccgaga aactatatag 7380 agaagtttga tcaagctatt ctgttttcta gatgggaggg tcttagccta acgattgcgg 7440 aatatatgtc tcagaagaaa acaattttag caacaaatat tggtggcatt aatgatttaa 7500 tcactgatgg tgaaacagga atgctgattg aagttggaga cttgaattca gcagtatcta 7560 aatctttcga gctaagaaat aataaagagg tttcgaatca attagcgaat aacgcttata 7620 ataaagttgt tgaacagttt tcgattgaaa aacagatggc tgagatagaa agtttattta 7680 tagagatgtg taacaatgag aaatagagac ttaaagaaaa tacaggttat ttgattgact 7740 tagagtggtc aaaatctgtc gaagaaaaat tatataaggc agcgaaaatg gatgcacaaa 7800 tgattaaagc agattttagg caaaggtttg cgattgatca gatgttaaag caaattaaaa 7860 caatttattt agcttgaatg aagaaagagg aggcataaat gctgattttg aaattaaaat 7920 ttcatcttaa atcgttattc cttaaatgga tttatcgatt actttatcta aaaaagtttc 7980 agtttggtgc acgcttgacg tttcgagatg ggtttcattt gttaattgaa aaatctggga 8040 aagttatcat cgggaatcat gtttttttta ataacttttg ttcaattaat gccatgttat 8100 cagtaacgat tggtgatgac tgtatttttg gtgaaaacgt taaaatttat gatcacaatc 8160 attgttatca aaataaaagt caacctattt caaaacaagg tttttcaact gctgctatcc 8220 agattggtcg taactgttgg ataggtagtc aagtgacgat tttaaaaggt gtaaccatag 8280 gtgataatag tatcattggt gctggtgtgg tagtttatca agatgtgcca gaaaattcga 8340 ttgttttatc taatggagaa attagaaagc gtggctaatt aaaatgtatc ttaaaagtct 8400 aatctctatt gttattccag tatataatgt agagaaatat ttagaaaaat gtttgcaatc 8460 tgttcaaaat cagacttaca ataattttga agtgatttta gtgaatgatg gctcaaccga 8520 ttcatcactt tcaatatgcg aaaaatttgt taatcaggat aaaagatttt ctgttttttc 8580 taaagaaaat ggtggtatgt catctgcacg aaattttgga attaaaaagg ctaaaggatc 8640 gtttatcaca tttgtagata gtgatgacta catagtaaaa gattatcttt ctcatttggt 8700 agctgggata aaaagtgaga cctctatagt ttgttcaaag ttttttcttg tagatgaaaa 8760 aggaagttta ttgactaaaa aagaggcacc taaaaagaaa tcagaagtcg tttcaattga 8820 ggaaagtatt aaaattcttc tgttgcaaca aaatggctat gatctcgctg tctggggaaa 8880 attatacccc gtttctttct ttgaaacaat ttctttccca gaaggaaaac tttacgaaga 8940 tatgggaaca acttacaaat tactaaaatt ggcaagtgaa gtggtcttct tggatgcgta 9000 tgattatgcc tacgtacagc gacctaatag tatcatgaat agttctttta atttgaaaaa 9060 gttggatata atagaaatgg ttcatgaaat ggaaaacgat atattagcac agtttccaaa 9120 tttagcatta tatgttaaga atcgagcatt tgccgcggaa gtgaaaatct ttttagagat 9180 tccaaaagaa aaagaatttg agcaagcgca aaagcaactt tggcatgata tcaaaaagaa 9240 tagaaaagca ccatttatga caaaaggtgc tagattgaag aataggctcg gagctagtct 9300 gtcgttttta ggtaaatctt tatttttgac tattgggaag cagttagtag atagataatg 9360 atattgaaag cgatacgata caatcgtaaa cttcttttgg tgttgactag gagttagctt 9420 gaaatttgaa tataaaggaa gcaacacatg gtaatttatt ttttactttt cccgatgatc 9480 gcaatgattt atttaatgac attgctctta cggcaaaaag cacaaatcca aaaaacgatt 9540 ttttgtgttc ttacgtttgg tacactaggc tttatttcag caagtcgtgc atcaagtgtt 9600 gggacggacg ttactttata cgaaaatatt tttaaatcta taaattacgg gataagtgct 9660 gagaataatt ggggatacgt catctataac aagctgattg gtagtgtatt tggctataca 9720 ggacatgaaa tcacggccgc taattcagtt ttgattacaa tacttattgg tatttttatt 9780 tggaaagtag cggaacatta ttttgttgcg acgtttttat acattagctt gttttattat 9840 gctacaagtt ttaatatttc aagacaattt attgccatgg ggcttgtatt ggtagcaatt 9900 tcttttgctt tagataaaaa ggttatgcct tggtttatct tgacagtttt ggctacctta 9960 tttcatgcga cagcaatcgt tgcttttcct gtctattggc ttacaaaagt acattgggat 10020 gtgaaaaaga cattaagtat ttttccaatc acgatttttg caagttttat ttttgatgct 10080 attttaaaca tttttgtacg ttttttccca cattatgaga tgtatatcac tggaacacaa 10140 tttaatattt cagatcaggg gcagggacgt gtggttttgg tcaaaatatt tatcttgctc 10200 attttgttta ctttattctt gttttataaa aaaagctatg ctttgatttc tgaatgtcat 10260 caaagtttga tagctttgac aaccgttgga ttaagtatcg gtattgtatt ttataataat 10320 attttactca atagaataga aatgttttat tcaattttaa gcatcgtatt tattccaatt 10380 gctatagatt acattagttt gaaatttaaa caaaaagatg ctgtgcgact aatgctgacg 10440 ataggtattt tgttaattac acttgtgcct tactatatac aggttagcgg taattattca 10500 ggaatattgc cttatgttat tcaacaataa aaaataaagt ttagagagga aataatggag 10560 gatagaaaga aacaagcaat tttgatacta tcccacagaa atactctcgc tctaaaatca 10620 acaatagagc ttttggattc tcaatacttt gatttctttc ttcatataga taaaaaaagt 10680 agaattcaag atttttttta tttaaaaaaa attacaaaat tctccactat tcatttttca 10740 gaaagaaaaa atgtacattg gggaggtttt tctatggtag aagcaatgtt tgcgctatta 10800 gaatgtgcac gtgatacagg agaatattct tattttcatt ttttatctgg agatgatatg 10860 ccaatcaaag ataatgaaat agtatttaat ttttttgaaa atagttatcc taaaaatttt 10920 attgatattc tagattttga aaatgtcaat aaaaattcat atttctacga accccctgag 10980 atgatagagg agagagtgaa gtactactat cctcatatgg atattctaaa cagaaaagga 11040 acaaatttca tagggaaaaa actaatttat ctacaaaaat tgttgaaagt taatcgcttg 11100 aaaaatagag agatagaaat tttcaagggt catcaatggt gtagtttgac aaatcaattt 11160 gtagatattt tattggataa agaggaaaga agagtaggta agtcttattt ttcatctagt 11220 ttaataccag atgaatgtta ttttcaaacg tttgctatga taaaaaaagt tgaaatttat 11280 caacagaaaa atatgtcagc acgcttaatt gattggacaa gagggaaacc atatatttgg 11340 cgacaggatg atttttttga aattatgaat gataaagatt caatgttttc taggaagttt 11400 gatgaaaatg tagatcgtaa aataattgaa gaaatttata taaaaataag aggaagaagt 11460 actgatgaag caaataaaat caaagataag agatttacaa aataatttta cctatgtttt 11520 tggaaagaaa acttttcttg gaaggggaga agcgattatc atagatgaac ctgagcatgg 11580 aaatttggga gatcaagcaa ttgcttttgc agaaaatcaa tttttagtaa atcatgtatc 11640 agtacgagat gtagaacatc ttatagaaag caaaactatt tcagaaataa aatctataaa 11700 aaaaaatatt ggaaaaaaag aattagtttt ttttcatggg ggaggaaatt tcgggacact 11760 ttatctaaag tatgagcgca ttagaagatt ggcagtatca aagcttccct ttaataaaat 11820 gattctattt cctcagtcaa tttcatttga agatagtagg tttggtcaga agcagctgaa 11880 taaaagtaaa aaaatataca gtcaaaatac aaattttatt ttgactgcaa gagaaccaaa 11940 atcttatggt ttaatgaaga aatgttttcc atataacaaa gtaatcttga caccggatat 12000 cgtgctctca tttaaatttg aagtcaccat ttctgatacg catattggga aagaaaagga 12060 tagtgttata acttatgaaa atcgtcaaca ctatcttgag ataaagtggg atgaaattgc 12120 gcagcatgag gtcgccttaa ctgatagatt acatggtatg attttttcat atatcacagg 12180 cacaccatgt gttgttttgg ctaataataa tcataaaatt gaaggaacat acaaacattg 12240 gttgaatgaa gtcaactata ttcgttttat tgaaaatccg actgttgaaa atattttaga 12300 tgcaatcaat gacttaaagc aaatcgaacc tcactatatt gatttatctg ataaatttca 12360 accactaatt gatgcgataa aagggtaaag gtttaatgaa taaatataaa aaactactat 12420 ccaactctct tgttttcacg ataggaaact taggcagcaa actgttagtc tttttactcg 12480 taccgctcta cacctatgcg atgacaccgc aagagtatgg tatggcagac ttatatcaaa 12540 caacagcaaa tctacttttg ccattaatta caatgaatgt atttgatgca actttacgtt 12600 ttgctatgga aaagtcaatg acaaaagaga gtgtgttaac aaattctctt gtggtttggt 12660 gttttagcgc ggtgttcact tgtttgggcg cttgtattat ctatgcgttg aacttgagta 12720 ataaatggta tttagcttta cttttaacct tcaacttatt tcaaggtgga caaagtatat 12780 taagccagta tgctagaggt ataggaaagt cgaaaatatt tgcagctggc ggagttattt 12840 taaccttttt gacaggcgct ttaaatattc tttttttggt atatttaccg cttgggatta 12900 cgggctattt aatgtccctg gttttagcga atgtaggtac gattctattt tttgctggca 12960 cactttccat ttggaaggaa attagtttta aaataattga taaaaaactg atttggcaaa 13020 tgctctatta tgccttacct ttgattccta gttccatcct gtggtggtta ctgaatgctt 13080 ctagtcgcta tttcgtttta ttctttttag gagcaggtgc taatggtctt ttggcggtcg 13140 ctaccaaaat tccaagtatt atttccattt ttaatacgat ttttacacag gcgtggcaaa 13200 tttcagccat agaagaatat gattctcatc aaaaatcaaa atattattcg gatgtttttc 13260 actacttagc aacttttcta ttgttaggga catcagcttt tatgattgtg cttaaaccaa 13320 ttgtcgaaaa agtcgtttca agtgactatg caagttcatg gcaatatgtt cctttcttta 13380 tgttgtcgat gctattttcc tcgttttctg atttttttgg gactaattat attgcggcta 13440 aacaaacaaa aggcgtattt atgacatcta tctatggtac cattgtttgt gtcttactcc 13500 aagtggtgct gctacccatc atcggcttgg atggcgcagg tttatcagcc atgcttggat 13560 ttttaacaac gtttttattg cgtgtcaaag atacgcaaaa atttgtggtg attcagatta 13620 agtggcggat tttgatcagt aatttattga tcgttttggc acaaatttta tgtttgtttt 13680 atctaccgag tgaatttttg tattttggtc ttgccctatt attttgtggc atgttagtgg 13740 ttaatcagcg tacaatttta tacattatca tggcgctaaa aataaaaaat aagacatttg 13800 gaatgaaatc ctcataaaaa tagacaggag gtgtatctcg aatggtatcg agatatatct 13860 cctgtctatt tttatgatac ttttgtgtta gctcaactca accgcctttt aatctcccaa 13920 caacaataat acccaatcaa acaacccaaa aaattcaaga taatatcact aatggcaaat 13980 gtgcccaaat aaaagataaa ttgaatggtt tcaattacta aaagagtgac caaactgaca 14040 atgacaaact gtttgaaatc agtattgata cagtaaaggc cacctaaagg aatgaagtag 14100 ataatattta gcacagcctc ttgaatcgtt ctgggatccg cttttataaa gtcaaaagga 14160 ttcagtgaca tcgcctgaaa atccgttatt ttagtaaaaa gtaccatgaa taacagtaat 14220 aaatacacac tgaaagcaag atagagataa ataactgaaa aatatttgag gtgatactgg 14280 ataccaaaca accagataat cagcgttaat aagagtatta aagtcaatgt ggtatagtca 14340 aagtggttaa tcaacctagc caggctttga tagcgagtga gaacgggcat aatcagccaa 14400 gtaatcgtcg cataactcag gataaatgtg atcaataaac tgctgaggta gatcatatat 14460 tttcgcaact gtttctaact ccttttcttg atgagattaa ccctatttta acatatttta 14520 aaactgtcat gtttttatga atttaaaata aatgttaaag aaaataaaaa ttcaccagtt 14580 ggttctgttg caaagttttc caaaaaatct attttagtgt aaaattgaga aaaaagacag 14640 agaggacaga gtaatgaatt attttaaagg caaacaattc aaaaaagacg tcattattgt 14700 ctctgttggt tactacctgc gttacaatct aagctatcgt taagttcagg aattgttata 14760 tgatcgtgga ataaatgttt gtcataccac gatttatcat tgagtgcaag agtacagcaa 14820 agtcctctat tatctttgga agaagaaaaa tagacaatcc ttatattcat ggaaaatgga 14880 cgaaacctat atcaaaatta agggacgttg gcattatctt tatcgtgcaa ttgatgcgga 14940 cggcttaacc ttagatatct ggttacgaaa gaaacgggat acgcaagcag cctatgcttt 15000 cttaaaacga ctccataaac aacagtttgg tgagccgaaa gcaattgtga ccgataaagc 15060 accttctctt ggctccgcct ttagaaagtt acagagtgtg ggtttatata ctaagacaga 15120 gcaccgaact gtgaagtatc ttaacaattt aatagaacag gaccatcaac ctattaaacg 15180 acggaataaa ttttatcaaa gtctccgtac agcctcttcc acgattaagg gcatggagac 15240 cattcgagga atatataaaa agaaccgaag aatggaacgc tcttcggctt ttcggtgtct 15300 actgaaacca aggtattaat gggaataaca gcctaagata tttggggttc agagagggag 15360 agggcgcgtt tgattttcaa acttcgcaac agaaccggtt gggtatatca cttttacaat 15420 ctaccactta tccaataatc aacgtatttt ttgacaccac aaccgtatga ctcacaaact 15480 tccaacacat gtatcataga aatcccccat ttattgaata tcaattaata attgctttaa 15540 agtcgctaag tattgttgcg tatacatttt ggtaatagtc atctttactt cttctgggga 15600 caaatatgtc gttttcttct caaaaaagtc aaccaatttt tcgtgggctt gcgtgacatt 15660 gccaggggtg tacaatgtcc cattagcacc atccttaata atgtcttccg gcccagttgg 15720 gcaatccgcc gaaaaacacg gtaccccata agacattgct tcagcaagaa ccatcggcaa 15780 tccctcaaat tttgaggtta agaaaagcaa atcaacctca tcctcatcca ggatatccca 15840 tggctgtgac tgccacccaa gccatgttat ccgttctgca atacctgcat ccttagcctg 15900 ccgtttcaaa gttgcttcat cgtcatcgtc gccagcccca atcacacgta aatgccacgg 15960 atacgcggtg gttgcgccta atatagatat gagttccgtc agattttttt gacttttact 16020 ttgcagccga ccaatataaa caaactcttt ggtatgaccg ttagttctcg gtatcaactt 16080 ttcttgcgga tcaattggat tatatactaa gaaaatacga ttcggcgaaa tccccaagcc 16140 ctgaagttgg tgttggatac ccgagctgat cgccagatga tagtcacaca atttaaagag 16200 cttcaacata cttggaaaac gtgtctctaa taatgaaaaa tgattccaag agaccagttt 16260 aaattttctt ctaaagattt ttcgagccat ccacgctgct aatatctgaa ctttactcat 16320 cgaaataacg atattcggtt gtgtttttaa aataaatact aatgtatccc agaaacgagt 16380 aaaactattt gtcttactat gtaacgttac tcgatcagca aatgcctgca tccacctttg 16440 gtctgaacac cctcctggca agaatagtga aaaattaaaa gactcatcac tagccgttaa 16500 aactttagca agtaccgtct ccgttccacc ctttccagtt aaatgtggat atataatcaa 16560 aactttcata acagcctccc aaatcatggt aagtaatttc tattttttct ggttccaccc 16620 ttaataccgt cacggtagcc atcttttagt tggttgaaga gatatttaat atacgcgttt 16680 gattttcaaa cttcgcaaca gaaccttgat attaatattt ttaccatttt ttataaattc 16740 attttacctt aaatttttaa aaaaagatag ttagaactgg acttaattca aataaatgga 16800 tacaaaatgg aatacatctt cttaggtcaa tgttcttttc ttattaaaat tctcaaaaac 16860 atttacattc aatgttcata aacccgtaat ttattctatg ttcatttata catctttcgg 16920 tagtgtaaaa taagttgtgt aaacacaaaa aggaataaat ccgttatagt agagttgcaa 16980 aacattacta gaaagagatt tattcctatg actcagttta ccacagaact acttaacttc 17040 ctagcccaaa agcaagatag tgatgaattt ttccgtactt ctcttgaaac agctatgaat 17100 gatctgcttc aagcagagtt atcagccttt ttagggtatg aaccttacga taaattaggc 17160 tataattctg ggaatagtcg taacggaagc tatgcacgga aattcgaaac caaatatggg 17220 actgttcagt tgagcattcc tagagatcgt aatgggaact ttagtccagc tttgcttccc 17280 gcttatggac gtcgagatga ccacttggaa gagatggtta tcaaactcta tcaaaccggt 17340 gtaacgactc gagaaattag tgatatcatc gagcgaatgt atgggtatca ctatagtcct 17400 gccacaattt ctaatatctc aaaagcaact caggagaatg tctctacttt tcatgagcga 17460 agcttagaag ccaattactc tgttttattt cttgacggaa cctatcttcc attaagacgt 17520 ggaaccgtta gtaaagaatg tattcatatc gcacttggca ttacaccaga aggacagaag 17580 gctgttcttg gatatgaaat cgccccaaat gaaaacaatg cttcttgatc taccctgtta 17640 gacaagcttc aaaaccaagg aatccaacag gtttctcttg tagtgaccga tggcttcaag 17700 gggcttgaag agattatcaa tcaggcttac ccattagcta aacaacaacg ttgcttaatt 17760 catattagtc gaaatctagc tagtaaagtg aaacgagcag atagagcggt tattctggag 17820 caatttaaaa caatttatcg tgctgaaaat ttagaaatgg cagtgcaagc tttagagaac 17880 tttatcgccg aatggaaacc aaagtatagg aaagtcatgg aaagtctgga gaatacggat 17940 aatcttttaa ctttttatca gtttccctac cagatttggc atagcattta ttcgacaaac 18000 ctcattgagt ctcttaacaa agaaatcaaa cgtcaaacga aaaagaaggt cctttttcct 18060 aacgaagagg ctctggaacg ttatttagtt accctgtttg aagattataa tttcaagcaa 18120 aatcaacgca tccataaagg gtttgaccaa tgtgctgaca cacttgaaag cttatttgat 18180 taacattctt caactctact tgagtgttta cacataatta ttgacagtat cgacatcaaa 18240 tgatgttgaa aaattactaa gatattttaa ttatgatttg ttagataaac cgactatatt 18300 taatggtgct aaatctgctt atatgctatc aggaacgaaa ctacattttg gtaaagagat 18360 gataatagaa gaagagcaag ccgctatggg agcatccatt aacgtttgaa tgggctggag 18420 gatttagatg atgatttcat caaaattgcc atgttgctgt gtcctgaaga ggctaatcag 18480 gtttcgcaag cctttaatcg tgattttgat ggtaatcttg tcgctgttcc aagcggtttt 18540 ggtgctattg acttcattca aaaaggcatg cacaaggctt gggggcttaa gcagcttctt 18600 aaccattggg acttgaatga ggcaaatagt atggcttttg gtgatggtga caatgatatt 18660 gagctcctgc gtatgactag tcattcttat gcgatggaaa atgccagccc tgctcttttg 18720 caagtggcag accaagtagc accgcatcat aaggatcaag gtgtcttgac tattttagaa 18780 gattatttag gtttatatta aaaaagggtg gtaaagtaat gaaattatat ttaatgtgac 18840 atggtgagac attatttaat acactcaatc ggattcaagg ttggtgtgat tcccctttga 18900 ctgaaaaagg tcaggaccaa gctcggcagg tgcgtgctta ttttgaaaaa catgatatga 18960 cttttgatca gtattactgc acgactactg aaagggcttc tgataccatt gaactggcca 19020 ctggacagac tgattatcaa cgtgttaagg ggcttaaaga aatgcacttc ggtatttttg 19080 aggatcaacc ggagtatctt catcccaaga catctgttgc ggggcatttt ggggaccact 19140 atgcccagtt tggtggggaa agtcaagatc agtttgtaga acgagtggtt gcgagtgcta 19200 aagaaatcgt tgaaaggcat cctgaacaat ctattttggc tgttagtcac gcaggatctt 19260 tgatgacttt tctccatgct gtatatccgg agcgtgcctt tcagtcttgt ccaggcaatt 19320 gtgccatctt agtctttgat tacgatggat cgaactttca ctttgtcaaa ctgattgatc 19380 ctttaacgga tcaagagttc gtggagtttt agtgtctttc tataatcaaa gatagtaata 19440 aatcctttct tagtgtataa tggaagggta ttttaaattt tggagtgcct atgaagttta 19500 caaagaatca gttcatttgg ttggttgtgc tgtttttcag ctgtttcttg atatatacct 19560 attgggaaac agttgtttcg atttgtaaca agatatttgt tgccagtcag cccttcttat 19620 ttggagcggg aattgctttt gtggtcaata tcctaatgtc tttttacgaa aaaatactga 19680 tcaagtttat accatttggt tttatcacta aaattaaacg tcccgtttcc ctgctcttgg 19740 cttttgcaac tatcggattg atctttactt gggtagtatt cactgtcctt cctgatttga 19800 ttgacagtat caataccttg attagtcaag accgctcagc tattaataat ttgattaatt 19860 ggttgcttaa gaataaatct ttgcagaaga tcattcaaga cctgggtggt gtgacacagg 19920 ttagagagct aatcaatagc tacagcgcac agttgcttca acaaattatg aatggcttga 19980 cgaatttctt gacttctttg actagcctac cgtcaacttt gattaatctt tttatcagta 20040 ttgtcttttc ttgctatgtc ttggttggga aggagaaact tggtagtcag gttaatcgct 20100 tagtcgatgt ttatttgggt cgttatggta agactttcca ctatgtggtt gcaattctca 20160 ataatcgttt ccacaatttc tttgtctatc agtcgattga agcctgcatt ttgggaacct 20220 tatgttatat tgggatgcgt atctttaatt ttccttacgc tgcgaccatt tctattctga 20280 ttggcttttc agcaatgata ccagttttgg gtgcctatat tggtgttact attggtacca 20340 ttttgattat gactcattcc gtgaccttgg cacttttatt tgtcgcctac gtggttattt 20400 tgcaacagtt tgaagggaat ctcatctatc cttatgtagt tggtggttct accggacttc 20460 cagtcgtttg ggttatcttg gctattacca tagggtctgc cttaggggga attctgggta 20520 tgctggtttc cgttccagta gccgcaaccc tttatcagat tgttaaggat aatgtggtta 20580 cacgagaaaa agccaaagca gttgcttctt tagaaaatag tgattaattc aaacagactt 20640 cggtctgttt tttcgtgtta tagtatcgga tttcaataat atagtataag tgtaatcgat 20700 ttctaagtgt catactatga gtaacttgaa caatgaaagt tgacaaaaga tgacttatac 20760 atttctgaaa taatttctct ggggtggagc aacagctgcc aaccagttcg aatgtgctta 20820 taacttagat ggcaaaggct tgtctgtgca agatgtgact cccaaaggtg gtgtcccttt 20880 tgaagccttt gactactgaa gaagcaacac cagctaatct aaagcttgaa ggtatagatt 20940 tctatcaccg ctataaagag gatattgcgc tatttgcaga gctgggcttc aaggtctttc 21000 gcatatcgat tgcttggtct cgtattttcc cgaacggtga tgatgctgag ccaaatgaag 21060 cagggtagcc ttctacaata aggtttttaa cgaattggct aagtataata tcgaacctct 21120 ggtcaccttg tctcactatg aaataccact aaacctggca cgtgagtaca acggatggac 21180 taatcgtaaa ataattggat tttatgagaa ttatgttcgt acagtcttta aacgctataa 21240 agataaggtc aaatattggt tgacctttaa tgaagtgaac tctgttctac atgcaccgtt 21300 tatgtcaggt ggtatggcaa ctcctatgga agggctatct aaaaaagaac tctaccaagc 21360 tgttcaccac gagttggtcg gttcagcttc agcaactaag attggccatg aaattaagcc 21420 tgagtttaaa atcggttgta tggttcttgc catgcctgct tacgggatga cagctactcc 21480 gttggaacag ttggcagttt ctgagtttga aaatcaaaac tatctcttct ctgatattca 21540 tgcatgtgga aaatatccga actatcttaa atattacttc aaagataatg gtattgaaat 21600 acaatttccc ctggcgacga tgaaatctta aagaataccg ttaattttat ttcattctct 21660 tatgctatgt ctgaagcaac agcacacaac ccagaagact ataaggttgg taaaggcaac 21720 atcttaggtg gtgtcgaaaa tccatacctt gagaaatctg aatggggctg ggctattgat 21780 ccaattggac ttcgtttggt tttagatgac ttttatgatc gttatcaatt gccattgttt 21840 attgtcgaaa atggtcctga tggtccgaca gttgaggatg attatcgtat gattaccttc 21900 aaaaacactt gattcaagtt ggtgaagctc ttcaagatgg agtagaactt ttgggctaca 21960 cgacttgggg accaattgat ttggtttcag cctcgactgc agaacttagt aaacgttatg 22020 gtttcatcta cgttgatcga aatgatgatg gtagtggtag cttggcacgt tataagaaaa 22080 attcatttgc ttggtataag tctgttatcg aaagtaatgg tgccgccctt tgtaaataga 22140 aaattgtgat gaatcccaca catgcttgca actcattttt agtatttcaa tacaatatta 22200 ttaataaaga ttccagctat ttgaataaag ttatagtatt atgatactat aacttttaag 22260 aggattaatt cactataact tacacatttt ttgaaaaagt ggtagaataa aagtgtgaaa 22320 acgttcttat attttctgaa gaagtagcta gactatttct ttgcttttcc tattcagatg 22380 gaggtaatgt tcatgaatga tttgaaaaaa gttcttttag ctggtattgg tttgactgct 22440 atgacagtag ataaggctga tagttttgtc caagaattgg ttgaaaaggg tcgtttgact 22500 gtcgaagaag gtaaggaatt agaacaagag ctaaaacgtc aaagtaaaga agggtctcaa 22560 gaatttttag ctaaacttga cgccaagaaa acttcagttg agtatgcgac taaagatgat 22620 gtgagacgtc ttgaagaaaa acttgatgct ttgctcagtc agaataaata aaatgtaagg 22680 ggactaaaat ggcaagtaaa cgattgagac atgtgttgaa ggttttctcg tcagttggtc 22740 tcctttttta tcgtgaaaaa caccttcctc aagaccaaca aacaacacct gtcaagctcc 22800 gtcaagcttt cgagcaattg ggaccaagtt ttgttaaaat tgggcaaatt ctatcgacac 22860 gctcggatct tttgccagag gcctatatcc gagaattatc aaaactccaa agtagtgttc 22920 ctccattgaa taaagaggag gtcatgactg ccattaggca agaattgcca actgatcttt 22980 ctgaggtttt cgtcgatttt tctaaagagc ctctggcctc tgggtctgtc gctcagaccc 23040 atcgagcaag gttgttgtct ggtcaggaag tgattataaa aattcagaga ccaggtattg 23100 atgatatcgt aaaggaagat atccagcttc ttattaagct tgcacggcat atacccaagc 23160 atttta 23166 // |
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