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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   AY033514; SV 1; linear; mRNA; STD; MUS; 1219 BP.
XX
AC   AY033514;
XX
DT   31-MAY-2001 (Rel. 67, Created)
DT   24-SEP-2008 (Rel. 97, Last updated, Version 2)
XX
DE   Mus musculus gamma-butyrobetaine 2-oxoglutarate dioxygenase mRNA, complete
DE   cds.
XX
KW   .
XX
OS   Mus musculus (house mouse)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea;
OC   Muridae; Murinae; Mus.
XX
RN   [1]
RP   1-1219
RA   Vaz F.M., Ofman R., Wanders R.J.A.;
RT   "Identification of Mouse gamma-Butyrobetaine Hydroxylase cDNA";
RL   Unpublished.
XX
RN   [2]
RP   1-1219
RA   Vaz F.M., Ofman R., Wanders R.J.A.;
RT   ;
RL   Submitted (27-APR-2001) to the EMBL/GenBank/DDBJ databases.
RL   Laboratory for Genetic Metabolic Diseases (F0-224), Clinical Chemistry and
RL   Pediatrics, Academic Medical Center, University of Amsterdam, Meibergdreef
RL   9, P.O. Box 22700, Amsterdam 1100 DE, The Netherlands
XX
DR   Ensembl-Gn; ENSMUSG00000041660; Mus_musculus.
DR   Ensembl-Tr; ENSMUST00000046233; Mus_musculus.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1219
FT                   /organism="Mus musculus"
FT                   /strain="FVB/N"
FT                   /mol_type="mRNA"
FT                   /sex="male"
FT                   /db_xref="taxon:10090"
FT   CDS             32..1195
FT                   /codon_start=1
FT                   /product="gamma-butyrobetaine 2-oxoglutarate dioxygenase"
FT                   /function="converts gamma-butyrobetaine
FT                   (4-trimethylammoniobutanoate), alpha-ketoglutarate and
FT                   molecular oxygen into carnitine
FT                   (3-hydroxy-4-trimethylammoniobutanoate), succinate and CO2"
FT                   /EC_number="1.14.11.1"
FT                   /note="gamma-butyrobetaine hydroxylase;
FT                   alpha-ketoglutarate-dependent dioxygenase; mediates the
FT                   last step in carnitine biosynthesis; iron (2+) and
FT                   ascorbate are co-factors"
FT                   /db_xref="GOA:Q924Y0"
FT                   /db_xref="InterPro:IPR003819"
FT                   /db_xref="InterPro:IPR012775"
FT                   /db_xref="MGI:1891372"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q924Y0"
FT                   /protein_id="AAK54388.1"
FT                   /translation="MHCAILKAEAVDGAHLMQIFWHDGAESLYPAVWLRDNCQCSDCYL
FT                   HSAKARKLLLEALDVNIRIDDLTFDRKKVYITWPNDHYSEFEANWLKKRCFSQQARARL
FT                   QGELFLPECQYWGSELQLPTLNFEDVLNDDDHAYKWLSSLKKVGIVRLTGAADKRGEII
FT                   KLGKRIGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQ
FT                   TVTGGDSEIVDGFNVCQKLKEKNPQAFHILSSTFVDFTDIGVDYCDFSVQSKHKIIELD
FT                   DKGQVVRVNFNNATRDTVFDVPIERVQPFYAALKEFVDLMNSKEYKYTFKMNPGDVITF
FT                   DNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVTNGN"
XX
SQ   Sequence 1219 BP; 354 A; 265 C; 288 G; 312 T; 0 other;
     ctgataggat ttatcaccaa agaccagaaa catgcactgt gccatcctaa aggcagaagc        60
     agtggatggg gctcatttga tgcagatctt ttggcacgat ggggcagagt ccctctaccc       120
     agcagtatgg ctgagagaca actgtcagtg ttcagactgc tacctacatt ctgcaaaagc       180
     tcggaaactt ctcctggaag ctcttgatgt aaacattaga atcgatgatt tgacatttga       240
     ccggaaaaag gtttatatca catggcccaa tgaccattac agtgaattcg aagctaactg       300
     gctgaagaaa agatgctttt ctcaacaggc cagagcaagg ctccaaggag aattgttttt       360
     accagaatgt cagtactggg gctcagaact ccagctgcca actctgaatt ttgaagatgt       420
     gttaaatgat gatgaccatg catacaaatg gctttccagt ctcaagaaag taggcattgt       480
     gagactcacc ggagcagctg acaaacgtgg tgagatcata aaacttggaa aaagaattgg       540
     cttcctgtac ctcacatttt atggacacac ttggcaagtg caggacaaga ttgatgccaa       600
     caatgtggct tatacaactg ggaagctcag cttccacact gactacccag ccctccacca       660
     tccacctggg gttcagcttc tgcattgtat caagcaaaca gtcacaggag gtgactctga       720
     aattgtggat gggtttaacg tgtgccaaaa gctcaaggag aagaaccctc aggctttcca       780
     tattctctcc tcgacctttg tggattttac agacattgga gtggattact gtgatttctc       840
     tgtgcaatct aaacacaaga ttatagagtt ggatgataaa ggccaagtgg ttcgcgtcaa       900
     cttcaacaat gcaaccagag atacagtctt tgatgtcccc atcgaaagag ttcagccttt       960
     ctacgctgct ctgaaagagt ttgttgacct catgaacagc aaagaataca agtatacctt      1020
     caagatgaat ccaggtgatg tgattacctt cgacaactgg cgcttgcttc atggacgtcg      1080
     tagctatgag gcgggaactg agatatcccg ccatctggaa ggagcgtatg ctgactggga      1140
     tgtagtgatg tcaaggcttc gtattctgag acagagagtc acgaatggga actgaatctc      1200
     ctggccttag actttagtg                                                   1219
//
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