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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   AM850907; SV 1; linear; genomic DNA; STD; INV; 1215 BP.
XX
AC   AM850907;
XX
DT   19-SEP-2007 (Rel. 93, Created)
DT   25-APR-2008 (Rel. 95, Last updated, Version 2)
XX
DE   Trypanosoma brucei brucei ALG3 gene for alpha 1-3 mannosyltransferase
XX
KW   ALG3 gene; alpha 1-3 mannosyltransferase.
XX
OS   Trypanosoma brucei brucei
OC   Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Trypanosoma.
XX
RN   [1]
RP   1-1215
RA   Ferguson M.A.;
RT   ;
RL   Submitted (02-SEP-2007) to the EMBL/GenBank/DDBJ databases.
RL   Ferguson M.A., Biological Chemistry and Drug Discovery, University of
RL   Dundee, Wellcome Trust Biocentre, Dow St, Dundee, Angus, DD1 5EH, UNITED
RL   KINGDOM.
XX
RN   [2]
RA   Manthri S., Guther M.L., Izquierdo L., Acosta-Serrano A., Ferguson M.A.;
RT   "Deletion of the TbALG3 gene demonstrates site-specific N-glycosylation and
RT   N-glycan processing in Trypanosoma brucei";
RL   Glycobiology 18(5):367-383(2008).
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1215
FT                   /organism="Trypanosoma brucei brucei"
FT                   /sub_species="brucei"
FT                   /strain="427"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:5702"
FT   CDS             1..1215
FT                   /gene="ALG3"
FT                   /product="alpha 1-3 mannosyltransferase"
FT                   /function="converts Man5GlcNAc2-PP-Dol to
FT                   Man6GlcNAc2-PP-Dol"
FT                   /EC_number="2.4.1.130"
FT                   /db_xref="GOA:A8E112"
FT                   /db_xref="InterPro:IPR007873"
FT                   /db_xref="UniProtKB/TrEMBL:A8E112"
FT                   /protein_id="CAO98979.1"
FT                   /translation="MEYRWLNRVLTVELCMSIIAFHLVHFTGIDWNAYMQEVKGFLDGE
FT                   LDYMKLKGDTGPLVYPGGFVWSHSALYFMTKGGVDVEMAQWLYLGIYVMVLVLVAHLYY
FT                   NSGLRGRLFIRLLLSKRIRSLFMFRLFNDCWAMFLVYLSVICFARGRRWTVGCLLYSMA
FT                   VSVKMNIFLFAPGLLLILCKSLPFTGVVRCLAVCALWQVVAGLPFLLHNPRSYIVRSFD
FT                   LGRVFTYRWTVNFKRISEEIFFSSKFSRSLLVMLAVSWLLVCFRRWSKRAYRRGRYEKR
FT                   EGTVVLVGASDEEVFHNVTLTLMESNMIGVIFARSLHYQFFLWFFYFVPFVLSATRLPL
FT                   VVKVVAFLAIQYGFEVYPSTTASSSVLLSGFLCVWLGMLLFPSEYSETTGKETTITLTA
FT                   VKRGK"
FT   mat_peptide     4..1212
FT                   /gene="ALG3"
FT                   /product="alpha 1-3 mannosyltransferase"
FT                   /EC_number="2.4.1.130"
XX
SQ   Sequence 1215 BP; 231 A; 260 C; 333 G; 391 T; 0 other;
     atggagtatc ggtggctgaa tagggttctc actgtggaat tatgcatgtc catcatagcc        60
     tttcatctcg tgcatttcac cggaatcgac tggaatgctt acatgcagga ggtgaagggc       120
     tttctggatg gggagctcga ctacatgaag ttgaagggtg acaccggccc tttggtgtac       180
     cccggcggtt tcgtatggtc ccattccgca ctttatttca tgacgaaagg tggtgttgat       240
     gtcgagatgg cacagtggct gtacttgggg atctatgtga tggtgctggt gttagttgca       300
     catttgtact acaactcggg gcttcgtggg aggttgttca ttcgtctcct cctttccaag       360
     cgaatccggt cactcttcat gttccggctc ttcaacgatt gttgggccat gtttctggtc       420
     tacttgtcgg ttatctgttt cgccaggggg cggcgatgga ctgttggatg tttgttgtac       480
     agtatggccg tgtcagtaaa aatgaacatt tttctctttg ctcctggtct tctactgatt       540
     ctgtgcaaat cacttccttt taccggggtg gtcagatgtc tcgcagtgtg tgcattgtgg       600
     caagtagttg cggggctgcc ctttcttctc cacaatccac ggtcatatat tgtacggtcg       660
     tttgaccttg gtcgtgtatt cacgtatcga tggactgtca atttcaagcg catctcggaa       720
     gagatatttt tttcgtccaa gtttagcagg agtttgttgg tgatgctagc tgtcagctgg       780
     ttgttagtgt gtttccggcg ttggtccaag cgtgcttacc ggcgtggccg gtatgagaag       840
     cgagagggga ctgtggtact tgtgggtgcg tcagatgaag aggtctttca caatgtcacc       900
     ttaaccctga tggagtctaa tatgatcggc gttatcttcg ctcgttcatt acactatcag       960
     ttttttctgt ggtttttcta cttcgtaccg tttgtcctct ctgccacacg actaccgctg      1020
     gtggtgaaag tggttgcctt tttagcaatc caatacggat tcgaggtgta cccgagcaca      1080
     accgcgtcat ccagtgttct tctgagtggc tttttgtgtg tatggctggg catgctcctt      1140
     ttcccctctg aatatagcga aactactgga aaagagacga cgataaccct tacagctgtg      1200
     aaaaggggaa agtag                                                       1215
//
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