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EBI DbfetchID AM270225; SV 1; linear; genomic DNA; STD; FUN; 46366 BP. XX AC AM270225; XX DT 28-JAN-2007 (Rel. 90, Created) DT 24-MAR-2007 (Rel. 91, Last updated, Version 3) XX DE Aspergillus niger contig An11c0080, complete genome. XX KW . XX OS Aspergillus niger OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; OC Aspergillus. XX RN [1] RP 1-46366 RA Pel H.J.; RT ; RL Submitted (01-MAY-2006) to the EMBL/GenBank/DDBJ databases. RL Pel H.J., DSM, 624-0295, P.O. Box 1, 2600 MA Delft, THE NETHERLANDS. XX RN [2] RP 1-46366 RX DOI; 10.1038/nbt1282 RX PUBMED; 17259976. RA Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J., RA Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R., RA Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X., RA Contreras R., Cornell M., Coutinho P.M., Danchin E.G.J., Debets A.J.M., RA Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M., RA d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J., RA Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W., RA van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M., RA Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X., RA van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A., RA Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E., RA Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J., RA Ussery D., Varga J., Vervecken W., van der Vondervoort P.J.J., Wedler H., RA Wosten H.A.B., Zeng A.P., van Ooyen A.J.J., Visser J., Stam H.; RT "Genome sequencing and analysis of the versatile cell factory Aspergillus RT niger CBS 513.88"; RL Nature Biotech 25(2):221-231(2007). XX RN [3] RP 621-3160 RX PUBMED; 2173790. RA Meier E., Kunz G., Haller O., Arnheiter H.; RT "Activity of rat Mx proteins against a rhabdovirus"; RL J. Virol. 64(12):6263-6269(1990). XX RN [4] RP 3773-5793 RX PUBMED; 2903861. RA Mirande M., Waller J.P.; RT "The yeast lysyl-tRNA synthetase gene. Evidence for general amino acid RT control of its expression and domain structure of the encoded protein"; RL J. Biol. Chem. 263(34):18443-18451(1988). XX RN [5] RP 621-3160 RX PUBMED; 7507812. RA Pavlovic J., Schroder A., Blank A., Pitossi F., Staeheli P.; RT "Mx proteins: GTPases involved in the interferon-induced antiviral state"; RL Ciba Found. Symp. 176:233-243(1993). XX RN [6] RP 16870-17809 RX PUBMED; 7993094. RA Trail F., Chang P.K., Cary J., Linz J.E.; RT "Structural and functional analysis of the nor-1 gene involved in the RT biosynthesis of aflatoxins by Aspergillus parasiticus"; RL Appl. Environ. Microbiol. 60(11):4078-4085(1994). XX RN [7] RP 34162-35127 RX DOI; 10.1007/BF00017802 RX PUBMED; 8616243. RA Taniguchi M., Sugiyama T.; RT "Isolation, characterization and expression of cDNA clones encoding a RT mitochondrial malate translocator from Panicum miliaceum L"; RL Plant Mol. Biol. 30(1):51-64(1996). XX RN [8] RP 3773-5793 RX DOI; 10.1021/bi9617926 RX PUBMED; 8952483. RA Agou F., Quevillon S., Kerjan P., Latreille M.T., Mirande M.; RT "Functional replacement of hamster lysyl-tRNA synthetase by the yeast RT enzyme requires cognate amino acid sequences for proper tRNA recognition"; RL Biochemistry 35(48):15322-15331(1996). XX RN [9] RP 9066-10642 RX DOI; 10.1074/jbc.272.30.19088 RX PUBMED; 9228094. RA Glerum D.M., Muroff I., Jin C., Tzagoloff A.; RT "COX15 codes for a mitochondrial protein essential for the assembly of RT yeast cytochrome oxidase"; RL J. Biol. Chem. 272(30):19088-19094(1997). XX RN [10] RP 15478-16440 RX PUBMED; 9353926. RA Summers R.G., Donadio S., Staver M.J., Wendt-Pienkowski E., RA Hutchinson C.R., Katz L.; RT "Sequencing and mutagenesis of genes from the erythromycin biosynthetic RT gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose RT and D-desosamine production"; RL Microbiology 143(Pt10):3251-3262(1997). XX RN [11] RP 15478-16440 RX DOI; 10.1007/s004380050566 RX PUBMED; 9393448. RA Gaisser S., Bohm G.A., Cortes J., Leadlay P.F.; RT "Analysis of seven genes from the eryAI-eryK region of the erythromycin RT biosynthetic gene cluster in Saccharopolyspora erythraea"; RL Mol. Gen. Genet. 256(3):239-251(1997). XX RN [12] RP 27237-28878 RX DOI; 10.1007/s004380050666 RX PUBMED; 9529523. RA Trapp S.C., Hohn T.M., McCormick S., Jarvis B.B.; RT "Characterization of the gene cluster for biosynthesis of macrocyclic RT trichothecenes in Myrothecium roridum"; RL Mol. Gen. Genet. 257(4):421-432(1998). XX RN [13] RP 15478-16440 RX DOI; 10.1007/s004380050680 RX PUBMED; 9563840. RA Salah-Bey K., Doumith M., Michel J.M., Haydock S., Cortes J., Leadlay P.F., RA Raynal M.C.; RT "Targeted gene inactivation for the elucidation of deoxysugar biosynthesis RT in the erythromycin producer Saccharopolyspora erythraea"; RL Mol. Gen. Genet. 257(5):542-553(1998). XX RN [14] RP 39734-42057 RX DOI; 10.1002/(SICI)1097-0061(199807)14:10<963::AID-YEA282>3.0.CO;2-X RX PUBMED; 9717242. RA Kitamoto H.K., Ohmomo S., Iimura Y.; RT "Isolation and nucleotide sequence of the gene encoding phosphoenolpyruvate RT carboxykinase from Kluyveromyces lactis"; RL Yeast 14(10):963-967(1998). XX RN [15] RP 25363-26484 RX DOI; 10.1074/jbc.274.9.5888 RX PUBMED; 10026212. RA Kuzuguchi T., Morita Y., Sagami I., Sagami H., Ogura K.; RT "Human geranylgeranyl diphosphate synthase. cDNA cloning and expression"; RL J. Biol. Chem. 274(9):5888-5894(1999). XX RN [16] RP 21675-23281 RX PUBMED; 10197990. RA Bosch R., Moore E.R., Garcia-Valdes E., Pieper D.H.; RT "NahW, a novel, inducible salicylate hydroxylase involved in mineralization RT of naphthalene by Pseudomonas stutzeri AN10"; RL J. Bacteriol. 181(8):2315-2322(1999). XX RN [17] RP 16870-17809 RX PUBMED; 10584035. RA Zhou R., Linz J.E.; RT "Enzymatic function of the nor-1 protein in aflatoxin biosynthesis in RT Aspergillus parasiticus"; RL Appl. Environ. Microbiol. 65(12):5639-5641(1999). XX RN [18] RP 29374-31668 RX PUBMED; 10589710. RA Yamada-Okabe T., Mio T., Kashima Y., Matsui M., Arisawa M., RA Yamada-Okabe H.; RT "The Candida albicans gene for mRNA 5-cap methyltransferase: identification RT of additional residues essential for catalysis"; RL Microbiology 145(Pt11):3023-3033(1999). XX DR EMBL-CON; AM270990. XX FH Key Location/Qualifiers FH FT source 1..46366 FT /organism="Aspergillus niger" FT /mol_type="genomic DNA" FT /clone="An11c0080" FT /db_xref="taxon:5061" FT CDS join(621..964,1127..2052,2236..2708,2765..2906,2985..3160) FT /locus_tag="An11g02390" FT /note="Function: Mx proteins are members of a family of FT interferon-inducible genes expressed when cells are treated FT with double-stranded RNA or virus infection. They are FT GTPases with an antiviral activity." FT /note="Title: strong similarity to antiviral determinants FT Mx1 - Rattus norvegicus" FT /db_xref="GOA:A2QVR7" FT /db_xref="InterPro:IPR001401" FT /db_xref="InterPro:IPR020850" FT /db_xref="UniProtKB/TrEMBL:A2QVR7" FT /citation=[3] FT /citation=[5] FT /inference="profile:COGS:COG0699" FT /inference="profile:PFAM:PF00350" FT /protein_id="CAK48306.1" FT /translation="MTPPEAAEMDSINLIASDMKELVRKIQDLRHIGIEDKMIVLPKIC FT VIGDQSAGKSSLIEGMSEIKVPRSAGTCTRCPMEINLCDGEPDQPWTCKVFLSRKYMFD FT ASKKIGKISKNETDPGYCQVKFSPNVVRLDITAPGFPSLSFYDLPGVISQAEHEEERYL FT VFLVENLVKHYILQQHCIVLLTLPMTNDATNSSAARIMQEIRGANARTMGVLTKPDRVQ FT TGESFAQWVEILEGDKFSLGHGYFVVRNNPDPAVEHYVAREEEDAFFASPPWATDLALY FT QEKFGTRRLQTALSSLLLEQIQGCLPDFIEKINAKADRIETELRTLPDPPSANVPYIIC FT GKLNQLKDQIRAHIDGGSANYPLQKIWSHIAMDFKRALIKTRPTVHLLSSSDKFPGPTG FT RDAEGSDSDCEMTTVPQPAKRKSPDQTDPKAIEIMNQMSVKHWYDPLSVFLVATHRLVR FT DMLHKQLDEVFLQYHQTGLYRELKRIIEGFLYKLRAAHFEHAQENFNIEYNKPFTLALS FT ALDQSIKSAYIFLAEKRRFARASSYLDAQGKYPRGDARREAELKKLTDVELGRDQFSQE FT LTMMATSRGYYDLASSRFIDSICQSVHTKLFAKCRDDLIKEIERELCIFDENELMEEDP FT DRQRRRQFLLREKERIDKAQEWLKLARKEDDQEDPFDNVRIKSQPPDDWTT" FT mRNA join(<621..964,1127..2052,2236..2708,2765..2906, FT 2985..>3160) FT /locus_tag="An11g02390" FT exon 621..964 FT /locus_tag="An11g02390" FT /number=1 FT intron 965..1126 FT /locus_tag="An11g02390" FT /number=1 FT exon 1127..2052 FT /locus_tag="An11g02390" FT /number=2 FT intron 2053..2235 FT /locus_tag="An11g02390" FT /number=2 FT exon 2236..2708 FT /locus_tag="An11g02390" FT /number=3 FT intron 2709..2764 FT /locus_tag="An11g02390" FT /number=3 FT exon 2765..2906 FT /locus_tag="An11g02390" FT /number=4 FT intron 2907..2984 FT /locus_tag="An11g02390" FT /number=4 FT exon 2985..3160 FT /locus_tag="An11g02390" FT /number=5 FT CDS join(3773..3988,4098..5685,5741..5793) FT /locus_tag="An11g02400" FT /EC_number="6.1.1.6" FT /note="Catalytic activity: ATP + L-lysine + tRNA(Lys) <=> FT AMP + diphosphate + L-lysyl-tRNA(Lys)." FT /note="Remark: alternate names for S. cerevisiae Krs1: GCD5 FT or YDR037W." FT /note="Title: strong similarity to cytosolic lysine--tRNA FT ligase Krs1 - Saccharomyces cerevisiae" FT /note="cytoplasm" FT /db_xref="GOA:A2QVR8" FT /db_xref="InterPro:IPR002313" FT /db_xref="InterPro:IPR004364" FT /db_xref="InterPro:IPR004365" FT /db_xref="InterPro:IPR006195" FT /db_xref="InterPro:IPR012340" FT /db_xref="InterPro:IPR016027" FT /db_xref="InterPro:IPR018149" FT /db_xref="InterPro:IPR018150" FT /db_xref="UniProtKB/TrEMBL:A2QVR8" FT /citation=[4] FT /citation=[8] FT /inference="profile:COGS:COG1190" FT /inference="profile:PFAM:PF00152" FT /inference="profile:PFAM:PF01336" FT /inference="similar to AA sequence:UniProtKB:SCKRS1.1" FT /protein_id="CAK48307.1" FT /translation="MADNNAVKEAEASMANLLLDEVTGEKVSKSELKRRQKNREKEAKK FT KEKEAAAPPKAEKKTSAEDEEANLTPNQYFEIRSKRINKLRETKNPDPYPHKFQVTDDL FT RKYLTDYEGLAKGEQKPEVAVRIAGRIYTKRASGAKLIFYDIRAEGVKVQVVAQAQHAT FT GGVPFEAQHEHLRRGDIVGIVGFPGRTSPKNRADGELSIFATEVVLLSPCLHAIPSEHF FT GLQDKEQRFRQRYLDLIMNDKSRNVFVTRSKIVRYIRNFFDNRDFVEVETPMMNAIAGG FT ATAKPFVTHHNDLDMNLFMRVAPELYLKMLIVGGLERVYELGRQFRNEGIDLTHNPEFT FT TCEFYWAYADVYDVMNLTEELVSGLVKHITGGYETTFHTQSGETYNVNWKAPWRRVEMI FT PALEEATGEKFPPGDQLHTAETGEFLKRVLKKTGVECSPPMTNARMLDKLVGEFIEETC FT VNPTFITGHPQMMSPLAKYHRQNVGLCERFEAFVCKKEIVNAYTELNDPFDQRLRFEEQ FT ARQKDQGDDEAQIIDENFCTSLEYGLPPTGGWGMGIDRLVMFLTDNYSIKEVLAFPFMK FT EDKTAHDTKPAAEVVGIEPQPEEGIVDYSPQIDKCDELLIRC" FT mRNA join(<3773..3988,4098..5685,5741..>5793) FT /locus_tag="An11g02400" FT exon 3773..3988 FT /locus_tag="An11g02400" FT /number=1 FT intron 3989..4097 FT /locus_tag="An11g02400" FT /number=1 FT exon 4098..5685 FT /locus_tag="An11g02400" FT /number=2 FT intron 5686..5740 FT /locus_tag="An11g02400" FT /number=2 FT exon 5741..5793 FT /locus_tag="An11g02400" FT /number=3 FT tRNA complement(6007..6098) FT /pseudo FT /gene="tRNA (unknown)" FT /locus_tag="An11e02410" FT /inference="profile:tRNAscan:1.4" FT CDS join(7773..8394,8450..8574) FT /locus_tag="An11g02420" FT /note="Similarity: the similarities of the ORF encoded FT protein to all matching proteins are mainly based on FT repetitive structures." FT /note="Title: weak similarity to viral protein EBNA-1 FT -EpsteinBarr virus TsBB6" FT /db_xref="UniProtKB/TrEMBL:A2QVR9" FT /protein_id="CAK48308.1" FT /translation="MDSRSTTAPNDTTADQSPVSEIHTEFRYIEAYEDVCDSCELFNMQ FT NAMSQCKSCGWRECRACTIETGGRRSHQFQGRRHFSPVDISELRTQAAIDHERRVARLG FT GWMSMRGLSRQRGHARGWRYSRRRRGEQIGGWGRRNGRGHRGNRQRGQEPAPGAAPAPA FT PSPAASPNTGEADLDGARAPETAEGAEMLYALGLEDSASRRSESGSTTSEEERQTRHAS FT CLILAKRAREQFETQQTDRATEECVT" FT mRNA join(<7773..8394,8450..>8574) FT /locus_tag="An11g02420" FT exon 7773..8394 FT /locus_tag="An11g02420" FT /number=1 FT intron 8395..8449 FT /locus_tag="An11g02420" FT /number=1 FT exon 8450..8574 FT /locus_tag="An11g02420" FT /number=2 FT CDS complement(join(9066..10179,10239..10642)) FT /locus_tag="An11g02430" FT /note="Function: the Cox15 protein from S. cerevisiae is FT required for the assembly of yeast cytochrome c oxidase." FT /note="Remark: alternate name for S. cerevisiae Cox15: FT YER141w." FT /note="Similarity: the ORF encoded protein shows also FT strong similarity to the human secreted protein described FT in patent WO9926973-A1." FT /note="Title: strong similarity to assembly factor of FT cytochrome c oxidase Cox15 - Saccharomyces cerevisiae" FT /note="localisation:mitochondrion" FT /db_xref="GOA:A2QVS0" FT /db_xref="InterPro:IPR003780" FT /db_xref="UniProtKB/TrEMBL:A2QVS0" FT /citation=[9] FT /inference="profile:COGS:COG1612" FT /inference="profile:PFAM:PF02628" FT /inference="similar to AA sequence:PIR:S50644" FT /protein_id="CAK48309.1" FT /translation="MASLGPSVPLLRSLSPRLSRELFTCRQCLVRTQNHATKSAFRRQF FT SALPFTQNSNSRANSALQSRARKLFASSLKRSASGSATAEAIAAQGEAAKAKSSFPDVS FT DKKVAYWLLASAASVFGIVVFGGLTRLTESGLSITEWRPVTGSLPPMNAEDWESEFSKY FT RASPEFQLLNPHMTLSEFKSIYYMEWIHRLWGRFVGLSFVLPAAYFVAAKKVSKPMALR FT LAGIAGLIGFQGFIGWWMVKSGLKDDLFAPGSHPRVSQYRLTAHLGAAFVCYTAMLWNG FT LAILRSHRLLADPEAGIKLLDALRDPKLKIFRRSVAALAALVFVTAMSGALVAGLDAGL FT IYNEFPFMGNGLAPPKSELFDERYSRHEDRSDLWWRNMLENPSLVQLDHRALAITTFTS FT IMALLAYTRGSPTMKRLLPPAAKKGVHGVVAFACMQVGLGISTLLYLVPTPLASAHQAG FT SLFLLTWVLVLGSRIWHPSRTAKLLQMAAKARGQALANAAAHAPRRI" FT mRNA complement(join(<9066..10179,10239..>10642)) FT /locus_tag="An11g02430" FT exon complement(9066..10179) FT /locus_tag="An11g02430" FT /number=1 FT intron complement(10180..10238) FT /locus_tag="An11g02430" FT /number=1 FT exon complement(10239..10642) FT /locus_tag="An11g02430" FT /number=2 FT CDS join(12124..12457,12515..12690,12728..13288,13341..13926, FT 13987..15296) FT /locus_tag="An11g02440" FT /note="Title: strong similarity to hypothetical secreted FT protein SCF41.31c - Streptomyces coelicolor" FT /db_xref="UniProtKB/TrEMBL:A2QVS1" FT /inference="similar to AA sequence:UniProtKB:SCO939105.67" FT /protein_id="CAK48310.1" FT /translation="MHLSYRLINTALLVQSVFATGTNDQVEPDIDYGSFQNPSSNVRPR FT FRYWVNDASMNLSVVAEDVKAMGKAGAGGLELLGYYLYGDSSNLDGQLQCPLQTDWTIF FT GFGSPAWKDLVDTVLTAAKECDLLVDLAIGPNQGAGVPAPYNDGGLLWDLAGFNSTLSS FT DEGFDGIVNSTSPSNDTYKILAESSLLDVTNLVSSNGHLQVKVNDTAGGSKYLFTYYLV FT HSEYREVQSPADVTAAVPQSPVTTYPQNGSWVVDHFSSQGALAVVDFWRQSLLDSETGA FT LIREVGNYLWEDSQEFTVSTFWTPRLQEVFQANRGYSINRFIPLLIGSGGGSIPDITYV FT TDELDAGASHTMDYQQTLTELNAEYLTSLKQWSNDLGIQFSAQVVYNLPMDMLANVPYV FT NGPECETLGFSDNIDSYRQFAGPAHLAGKRIITNEAGAELSKVYQESIPELLWTLKRSF FT AGSVNQFVLHGYPNSGNYGNTTWPGFTTFSYLFSEMHGPRQPAFAYYSDFLDWLSRNQF FT VEQTGIPKVDIAFWSKSTTYKTVPTVYSPVDLQSAGYTYEYLSPDNFALPGAFVSNGTF FT APNQQAFKALVVRANETLTASGVAKLVEYAHSKLPIIFSGGLPSNFSGYNPEAASLAVS FT TIKNLTSSNNVHIVPYDNLAATLRSLGILPRTSVSANRTWYTTWRHDTKTLTDYVYVYN FT DAAGVPFGGGISSGTISFETTGTPFLYDTWSGDISALSIYQKSENHVTIPLTLAGNQSV FT IIGFHKNFQPTLHLQNTTGGILGATGNATSLTVLRSVDQESRDIYLSNGKSVTLGPMLT FT PTITLGNWTLIVESWTAPSDLYNVELGPKRTNQTFDLPTLLPWNQVSASLANVSGIGYY FT STTFDWPPQATNGTVSGAIIDVGPIVHTARVTVNGHVLPPGEITWAKWDIGYFLRRGQN FT TVEVVVSTPLGNVLRTYWDKLETSGKLATAVVPSPPDEADYGLIAPVRIIPYRKDQVA" FT mRNA join(<12124..12457,12515..12690,12728..13288,13341..13926, FT 13987..>15296) FT /locus_tag="An11g02440" FT exon 12124..12457 FT /locus_tag="An11g02440" FT /number=1 FT sig_peptide 12124..12180 FT /locus_tag="An11g02440" FT /inference="protein motif:SignalP:2.0" FT mat_peptide join(12181..12457,12515..12690,12728..13288,13341..13926, FT 13987..15293) FT /locus_tag="An11g02440" FT intron 12458..12514 FT /locus_tag="An11g02440" FT /number=1 FT exon 12515..12690 FT /locus_tag="An11g02440" FT /number=2 FT intron 12691..12727 FT /locus_tag="An11g02440" FT /number=2 FT exon 12728..13288 FT /locus_tag="An11g02440" FT /number=3 FT intron 13289..13340 FT /locus_tag="An11g02440" FT /number=3 FT exon 13341..13926 FT /locus_tag="An11g02440" FT /number=4 FT intron 13927..13986 FT /locus_tag="An11g02440" FT /number=4 FT exon 13987..15296 FT /locus_tag="An11g02440" FT /number=5 FT exon complement(15478..16440) FT /locus_tag="An11g02450" FT /number=1 FT CDS complement(15478..16440) FT /locus_tag="An11g02450" FT /EC_number="1.1.1.-" FT /note="Function: the EryBIV aldohexose 4-ketoreductases is FT part of the eryB gene cluster from S. erythraea which is FT involved in the L-mycarose biosynthesis." FT /note="Pathway: the eryA (polyketide synthase genes), eryB FT (L-mycarose biosynthesis genes) and the eryC (D-desosamine FT biosynthesis genes) gene clusters from S. erythraea are FT involved in the erythromycin biosynthetic pathway." FT /note="Remark: the EryBIV aldohexose 4-ketoreductase from FT S. erythraea is identical to the protein described in FT patent WO9905283-A2." FT /note="Similarity: the ORF encoded protein shows strong FT similarity to the hypothetical proteins YLL056c from S. FT cerevisiae and SPBC2A9. 02 from S. pombe." FT /note="Title: similarity to aldohexose 4-ketoreductase FT EryBIV - Saccharopolyspora erythraea" FT /db_xref="GOA:A2QVS2" FT /db_xref="InterPro:IPR001509" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:A2QVS2" FT /citation=[10] FT /citation=[11] FT /citation=[13] FT /inference="profile:COGS:COG0451" FT /inference="profile:COGS:COG1088" FT /protein_id="CAK48311.1" FT /translation="MPLIFLTGGSGYLGHAITTHALSKNYTIHSLSRSPESDAKITSLG FT AVPIRGDLTTHSVLREQSQKADIVIHLADPMAGNYSLPYEERIRIDDEAVTAIAEGLVG FT TNKPLVVTSGSLVVAATGTETDENSALWEEGKALNERIVSERKNLRWWEEKGVRVIVIR FT LPPFVYGRGGSGVGLFMGMFWNGGDGGKKEVKVVKEAEEVVTSAVHVEDAADLYLLAAE FT RAGAGEVFNGCSEWGVTFGELGRAMADVLGVEVGLVGFEEAKGVWGEFFARFLSTENRA FT SGGKAMRVLGWAPKKVGIVEEVRHGSYVEVAERLKNGAA" FT mRNA complement(<15478..>16440) FT /locus_tag="An11g02450" FT mat_peptide complement(15481..16392) FT /locus_tag="An11g02450" FT sig_peptide complement(16393..16440) FT /locus_tag="An11g02450" FT /inference="protein motif:SignalP:2.0" FT CDS complement(join(16870..16941,17002..17101,17156..17690, FT 17767..17809)) FT /locus_tag="An11g02460" FT /EC_number="1.1.1.-" FT /note="Function: the nor-1 gene is involved in aflatoxin FT biosynthesis in Aspergillus parasiticus. Recombinant Nor-1 FT expressed in Escherichia coli converted the 1' keto group FT of norsolorinic acid to the 1' hydroxyl group of averantin FT in crude E. coli cell extracts in the presence of NADPH." FT /note="Remark: aflatoxins comprise a group of FT polyketide-derived carcinogenic mycotoxins." FT /note="Title: strong similarity to norsolorinic acid FT ketoreductase nor-1 - Aspergillus parasiticus" FT /db_xref="GOA:A2QVS3" FT /db_xref="InterPro:IPR002198" FT /db_xref="InterPro:IPR002347" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:A2QVS3" FT /citation=[17] FT /citation=[6] FT /inference="profile:COGS:COG1028" FT /inference="profile:PFAM:PF00106" FT /inference="similar to AA sequence:SWISSPROT:NOR1.ASPPA" FT /protein_id="CAK48312.1" FT /translation="MSSPTIYLITGASRGIGLALTQTLLLLPNTTVIATMRNPTTNSLY FT TNPPPTSPTSTLILLPLDIQSTTSITTAIETLKSKHNITHIDTVISNAGYYNDATHRVD FT NIPLSTVQSHLDVNTLGTIRLFQGVYDMLKKSTKPMFVSVSSFLGSIGGLEEEFFPGAA FT YGVSKAASNWVTRKMHVENEEMVCFMVHPGFVKTEMGNACAKSIGLEEAFAEPKECAEA FT LVKLIASATRETVGGRFISWRGEEVPF" FT mRNA complement(join(<16870..16941,17002..17101,17156..17690, FT 17767..>17809)) FT /locus_tag="An11g02460" FT exon complement(16870..16941) FT /locus_tag="An11g02460" FT /number=1 FT mat_peptide complement(join(16873..16941,17002..17101,17156..17631)) FT /locus_tag="An11g02460" FT intron complement(16942..17001) FT /locus_tag="An11g02460" FT /number=1 FT exon complement(17002..17101) FT /locus_tag="An11g02460" FT /number=2 FT intron complement(17102..17155) FT /locus_tag="An11g02460" FT /number=2 FT exon complement(17156..17690) FT /locus_tag="An11g02460" FT /number=3 FT sig_peptide complement(join(17632..17690,17767..17809)) FT /locus_tag="An11g02460" FT /inference="protein motif:SignalP:2.0" FT intron complement(17691..17766) FT /locus_tag="An11g02460" FT /number=3 FT exon complement(17767..17809) FT /locus_tag="An11g02460" FT /number=4 FT CDS join(19334..19378,19509..19589,19628..19780,19947..20529, FT 20579..20662,20713..21470) FT /locus_tag="An11g02470" FT /note="Remark: the ORF encoded protein is N-terminally FT extended in comparison to all other matching homologs." FT /note="Title: similarity to hypothetical protein F27J15.2 FT -Arabidopsis thaliana" FT /db_xref="GOA:A2QVS4" FT /db_xref="InterPro:IPR012935" FT /db_xref="InterPro:IPR013909" FT /db_xref="UniProtKB/TrEMBL:A2QVS4" FT /inference="similar to AA sequence:PIR:C96527" FT /protein_id="CAK48313.1" FT /translation="MDKCKLIIFGDSRRSISGQSSIHDGLYHKECLMTSVNWYRTQFIQ FT LGTRSAACKKTSLSFLAEMTFFRGCRDPDRYDQPCPVSDVLSGLSHIIRHQLRGHSKIQ FT TPLSQRPLQLHNAITSACWKMSYAVETKKRKFHRVLESLTKPSTSDSTKSATAEAPTTA FT RDASKKKARLDAPNFSLARNSLLKVARPSSRDSSVSSTSRPSFVPWDRERFLERLETFR FT RVDRWAPKPSAISEVEWAKRGWVCTDVARVTCAGNCGGSVVVKLPDELDELDGFDADKV FT QERKEVRAKLVDEYVERLVKGHGETCPWRNKGCDATIHRLPLANPDIAISGLEKRYSNL FT IKMADQLPAADVIHTPESFDIEALIKILPASFNGPGESTRMESIENNTEGENGKENAHN FT SEPEPFVPRNAFILAFFGWDSVPDGTAGLVGCSVCFRRLGLWMYKPKANGDEALYDSLE FT VVNEHMDYCPWVNGKAQSGTGRATEKLEGLRSGWELLGQALNVRHRRLNRSTTSGDSRA FT VSEVPSTDEPVVDDVNPEVKKASDREWWAKLRRMRQVLNVSSPRKKPTSQ" FT mRNA join(<19334..19378,19509..19589,19628..19780,19947..20529, FT 20579..20662,20713..>21470) FT /locus_tag="An11g02470" FT exon 19334..19378 FT /locus_tag="An11g02470" FT /number=1 FT intron 19379..19508 FT /locus_tag="An11g02470" FT /number=1 FT exon 19509..19589 FT /locus_tag="An11g02470" FT /number=2 FT intron 19590..19627 FT /locus_tag="An11g02470" FT /number=2 FT exon 19628..19780 FT /locus_tag="An11g02470" FT /number=3 FT intron 19781..19946 FT /locus_tag="An11g02470" FT /number=3 FT exon 19947..20529 FT /locus_tag="An11g02470" FT /number=4 FT intron 20530..20578 FT /locus_tag="An11g02470" FT /number=4 FT exon 20579..20662 FT /locus_tag="An11g02470" FT /number=5 FT intron 20663..20712 FT /locus_tag="An11g02470" FT /number=5 FT exon 20713..21470 FT /locus_tag="An11g02470" FT /number=6 FT CDS complement(join(21675..22151,22208..22578,22699..22907, FT 22980..23281)) FT /locus_tag="An11g02480" FT /EC_number="1.14.13.1" FT /note="Catalytic activity: salicylate + NADH + O2 = FT catechol + NAD+ + H2O + CO2." FT /note="Function: nahG of P. stutzeri catalyzes the FT formation of catechol from salicylate, a key intermediate FT in naphthalene catabolism." FT /note="Induction: nahG of P. stutzeri is induced and FT expressed upon incubation with salicylate." FT /note="Pathway: nahpthalene, salicylate, and phenylalanine FT metabolism." FT /note="Title: strong similarity to salicylate hydroxylase FT nahW - Pseudomonas stutzeri" FT /db_xref="GOA:A2QVS5" FT /db_xref="InterPro:IPR002938" FT /db_xref="InterPro:IPR003042" FT /db_xref="UniProtKB/TrEMBL:A2QVS5" FT /citation=[16] FT /inference="profile:COGS:COG0644" FT /inference="profile:PFAM:PF01360" FT /protein_id="CAK48314.1" FT /translation="MANTQQPQFRVLIVGGSVAGLTLAHCLERANIEYLILEKGDDIAP FT QVGASIGIMPNGGRILEQLGLFGEIERVIEPLHQANISYPDGFCFSNVYPKVLGDRFGY FT PVAFLDRQKFLQIAYEGLTKKHNVLTRKRVVEVRQLEHGITVAVADGTEYEVDLVVGAD FT GVHSRVRSMTVEYVCVFGISSAIPGLEISEQINGIYDHLSILTIHGRHGRVFWFVIQKL FT DRKYVYPDVPRFSDEDAVQLFERVKHVRFWKDICVGDLWKNREVSSMTALEEGLFETWH FT HERMVLIGDSVHKMTPNFGQGANCAIEDAAALSSLLHDLINARGVCKPSNSQVQHLLQQ FT YQETRYSRMVGMCRTAASVSRIQARDGILNTVFGRYWAPYAGNLPADLASKVMADAEVV FT SFLPLPGRSGPGWEMYRRKGKREQIQWVLIIFSLITLGGLCIWLQSNASYVVE" FT mRNA complement(join(<21675..22151,22208..22578,22699..22907, FT 22980..>23281)) FT /locus_tag="An11g02480" FT exon complement(21675..22151) FT /locus_tag="An11g02480" FT /number=1 FT mat_peptide complement(join(21678..22151,22208..22578,22699..22907, FT 22980..23209)) FT /locus_tag="An11g02480" FT intron complement(22152..22207) FT /locus_tag="An11g02480" FT /number=1 FT exon complement(22208..22578) FT /locus_tag="An11g02480" FT /number=2 FT intron complement(22579..22698) FT /locus_tag="An11g02480" FT /number=2 FT exon complement(22699..22907) FT /locus_tag="An11g02480" FT /number=3 FT intron complement(22908..22979) FT /locus_tag="An11g02480" FT /number=3 FT exon complement(22980..23281) FT /locus_tag="An11g02480" FT /number=4 FT sig_peptide complement(23210..23281) FT /locus_tag="An11g02480" FT /inference="protein motif:SignalP:2.0" FT CDS complement(join(23955..24168,24222..24340,24419..24739)) FT /locus_tag="An11g02490" FT /note="Title: weak similarity to endocarditis specific FT antigen region from patent WO9520658-A2 - Streptococcus FT oralis" FT /db_xref="UniProtKB/TrEMBL:A2QVS6" FT /protein_id="CAK48315.1" FT /translation="MDGFDHSTAPQEYNELKWLANIFVVGMAVGWVAHYVEMIHTSFRD FT RTYCMTIGGLCINFAWEIVFCTMYPAKGIIERVAFLVGISLDLGVIYAGIKNAPNEWHH FT SAIVGPAQAYTWGAIACQLFISIGNVFQLLSRGNTRGASWTLWISRFFGSTSAIGFALV FT RYFRWWEAFSYINCPLVIWSVAMFFLFEILYGVLFCSVKRQEKSSQRGIKHKER" FT mRNA complement(join(<23955..24168,24222..24340,24419..>24739)) FT /locus_tag="An11g02490" FT exon complement(23955..24168) FT /locus_tag="An11g02490" FT /number=1 FT intron complement(24169..24221) FT /locus_tag="An11g02490" FT /number=1 FT exon complement(24222..24340) FT /locus_tag="An11g02490" FT /number=2 FT intron complement(24341..24418) FT /locus_tag="An11g02490" FT /number=2 FT exon complement(24419..24739) FT /locus_tag="An11g02490" FT /number=3 FT CDS join(25363..25689,25736..26088,26157..26484) FT /locus_tag="An11g02500" FT /EC_number="2.5.1.1" FT /EC_number="2.5.1.10" FT /EC_number="2.5.1.29" FT /note="Catalytic activity: Dimethylallyl diphosphate + FT isopentenyl diphosphate <=> diphosphate + geranyl FT diphosphate." FT /note="Catalytic activity: the human GGPPS enzyme also FT catalyzes: geranyl diphosphate + isopentenyl diphosphate FT <=> diphosphate + trans,trans-farnesyl diphosphate." FT /note="Catalytic activity: the human GGPPS enzyme also FT catalyzes: trans-trans-farnesyl diphosphate + isopentenyl FT diphosphate <=> diphosphate + geranylgeranyl diphosphate." FT /note="Function: the human GGPPS enzyme catalyzes the FT trans-addition of the three molecules of IPP (isopentenyl FT diphosphate) onto DMAPP(dimethylallyl diphosphate) to form FT geranylgeranyl pyrophosphate, an important precursor of FT carotenoids and geranylatedgeranylated proteins." FT /note="Title: strong similarity to geranylgeranyl FT pyrophosphate synthase GGPPS - Homo sapiens" FT /db_xref="GOA:A2QVS7" FT /db_xref="InterPro:IPR008949" FT /db_xref="InterPro:IPR017446" FT /db_xref="UniProtKB/TrEMBL:A2QVS7" FT /citation=[15] FT /inference="profile:COGS:COG0142" FT /protein_id="CAK48316.1" FT /translation="MAALPDVASIPLPLVATLGIAPLVFYLVLDRFGPLWPNSKTFLIG FT KKKPETVTSFECPYAYIRQIYGKHHWNPFVQKLSPRLKDEDPAKYKMVLEIMDAIHLCL FT MLVDDITDNSDYRKGKPAAHRIYGPSETANRAYYRVTQILNETVQRFPKLAKFLLQNLE FT EILEGQDLSLIWRRDGLGSLSTVPEERVAAYRKMASLKTGALFRLLGQLVMEDQSMDGT FT MTTLAWCSQLQNDCKNVYSSEYAKAKGALAEDLRNRELSYPIILALEAPEGHWVASALE FT TSSPRNIRKALAVIQSERVRNACFRELKSASASVQDWLAIWGRNEKMNLKSQQT" FT mRNA join(<25363..25689,25736..26088,26157..>26484) FT /locus_tag="An11g02500" FT exon 25363..25689 FT /locus_tag="An11g02500" FT /number=1 FT intron 25690..25735 FT /locus_tag="An11g02500" FT /number=1 FT exon 25736..26088 FT /locus_tag="An11g02500" FT /number=2 FT intron 26089..26156 FT /locus_tag="An11g02500" FT /number=2 FT exon 26157..26484 FT /locus_tag="An11g02500" FT /number=3 FT CDS join(27237..27666,27698..27877,27932..28263,28327..28878) FT /locus_tag="An11g02510" FT /EC_number="1.14.-.-" FT /note="Pathway: the cytochrome P450 monooxygenase TRI4 from FT M. roridum is involved in the biosynthesis of FT trichothecenes, which are toxic sesquiterpenoids produced FT by certain fungi and plants." FT /note="Remark: the M. roridum TRI4 gene can successfully FT complement a F. sporotrichioides TRI4-mutant." FT /note="Title: similarity to cytochrome P450 monooxygenase FT TRI4 - Myrothecium roridum" FT /db_xref="GOA:A2QVS8" FT /db_xref="InterPro:IPR001128" FT /db_xref="UniProtKB/TrEMBL:A2QVS8" FT /citation=[12] FT /inference="profile:COGS:COG2124" FT /protein_id="CAK48317.1" FT /translation="MTPPLLPTSLISAILGITAHLTYFIHADLEKHVVFLVNCLIFWPS FT LGLIALFILGYRDISQWIGPAILSFHFSLLASIVIYRYFFHALDGFPGPKLARITALWD FT FKNTVLNAKWYIKVKEMHGVYGDVVRISIPPLFHSSHVIWNYPSTTHLRSKISTAWGPH FT ASRDRSTIYIIRIDRCKWREIRRFIRRGGDCGIGGLRRKAALAGYEPYLLEHCKDIVRV FT IESRSSQAQEATALIDGFAWDSMGIFAFGKSFNMLHGEPPKMLQMMRMMGRGASALLSS FT SWLVILMRGMVGVRRFTDRWLEWCAQCVEERSRVETNRRDLFSYLIEELSSEGDQSIGG FT VDGDLVRDSELAITAGSDTAASTLNALFYLLARHPDKLRRLQEEIDTAVPADEELSHAA FT LVKKPYLEGCINESLRLCPAVLSGLQRETGPEGLRTAGVYIPPGMIVSVPTYTVQRGRS FT LTFPVKIRADFLSRRPAQLPPSKRIHPRKVVHPARASHS" FT mRNA join(<27237..27666,27698..27877,27932..28263,28327..>28878) FT /locus_tag="An11g02510" FT exon 27237..27666 FT /locus_tag="An11g02510" FT /number=1 FT sig_peptide 27237..27293 FT /locus_tag="An11g02510" FT /inference="protein motif:SignalP:2.0" FT mat_peptide join(27294..27666,27698..27877,27932..28263,28327..28875) FT /locus_tag="An11g02510" FT intron 27667..27697 FT /locus_tag="An11g02510" FT /number=1 FT exon 27698..27877 FT /locus_tag="An11g02510" FT /number=2 FT intron 27878..27931 FT /locus_tag="An11g02510" FT /number=2 FT exon 27932..28263 FT /locus_tag="An11g02510" FT /number=3 FT intron 28264..28326 FT /locus_tag="An11g02510" FT /number=3 FT exon 28327..28878 FT /locus_tag="An11g02510" FT /number=4 FT CDS join(29374..29535,29817..30566,30627..31109,31182..31357, FT 31410..31668) FT /locus_tag="An11g02520" FT /EC_number="2.1.1.56" FT /note="Catalytic activity: S-adenosyl-L-methionine + FT G(5')PPPR-RNA <=> S-adenosyl-L-homocysteine + FT m7G(5')PPPR-RNA." FT /note="Function: CaAbd1 from C. albicans transfers a methyl FT group from S-adenosylmethionine to the N7 position of FT guanine of the mRNA cap." FT /note="Remark: CaAbd1 expressed as a fusion with FT glutathione S-transferase (GST) displayed cap MTase FT activity in vitro. it also rescued S. cerevisiae abd1delta FT null mutants." FT /note="Title: strong similarity to FT mRNAcap-guanine-N7-methyltransferase CaAbd1 - Candida FT albicans" FT /db_xref="GOA:A2QVS9" FT /db_xref="InterPro:IPR004971" FT /db_xref="UniProtKB/Swiss-Prot:A2QVS9" FT /citation=[18] FT /inference="profile:COGS:COG0500" FT /inference="profile:COGS:COG2226" FT /inference="profile:PFAM:PF03291" FT /inference="similar to AA sequence:UniProtKB:AB020965.1" FT /protein_id="CAK48318.1" FT /translation="MASKEEERTGQRPSISMYDPARDRWEEQPVVPAEPASASASIEAT FT PTQTSEAKPVHDSTVTSTSESLHLPQTTTIEPSQQPEQQQKQPPIPTPPSSQSRRKHKI FT NKMGDYYRSGSADAYAEQSSPAADSHKRKLEDETSEQQPPADQANDRPISKRKRLEERH FT QKLRKRGQAPPSAYSRRDGDETAARAAPRPRSPSPPLPPRSPSPEVQARQRKRPGGGAR FT RGLVDPQTLRRRQEERERALEEDAMRNSQSRGVTDIVRQHYNAVPQRGREWRKTESKIK FT GLRSFNNWVKSTLIQKFSPDEEFEKRLLVIDLGCGKGGDLGKWQLAPQPVDLYVGLDPA FT EVSIIQARERYAGMRSGRGPRGGRRGGPPLFHGEFRSKDCFGEWLGDVDIVQQVGIDPN FT VGPGGSMMASRWGGGGFDVVTSMFAIHYAFESEEKARQMLRNVAGCLKKGGRFIGVCPN FT SDIISARVEEEAKAEWGNSIYRVRFPGDTPEDGIFRPPFGWKYSYFMEEAVGEIPEYVV FT PWEAFRALTEEYNLELQYRKPFMEVWRDEKDDPELGPLSERMGVRDRTTGELTMTPEEQ FT EAVSKYTPLGFTSAEGESANGTGFYHAFCFYKV" FT mRNA join(<29374..29535,29817..30566,30627..31109,31182..31357, FT 31410..>31668) FT /locus_tag="An11g02520" FT exon 29374..29535 FT /locus_tag="An11g02520" FT /number=1 FT intron 29536..29816 FT /locus_tag="An11g02520" FT /number=1 FT exon 29817..30566 FT /locus_tag="An11g02520" FT /number=2 FT intron 30567..30626 FT /locus_tag="An11g02520" FT /number=2 FT exon 30627..31109 FT /locus_tag="An11g02520" FT /number=3 FT intron 31110..31181 FT /locus_tag="An11g02520" FT /number=3 FT exon 31182..31357 FT /locus_tag="An11g02520" FT /number=4 FT intron 31358..31409 FT /locus_tag="An11g02520" FT /number=4 FT exon 31410..31668 FT /locus_tag="An11g02520" FT /number=5 FT CDS join(32075..32790,32892..33774) FT /locus_tag="An11g02530" FT /note="Title: similarity to hypothetical protein CAF06139.1 FT - Neurospora crassa" FT /db_xref="GOA:A2QVT0" FT /db_xref="InterPro:IPR004181" FT /db_xref="UniProtKB/TrEMBL:A2QVT0" FT /inference="profile:COGS:COG5627" FT /protein_id="CAK48319.1" FT /translation="MPKRSRPPPPTATPGPSGRNRNRDRDTTPPLPPYQPPTSTLTTLS FT HQPTTAPALSALLATHTSSTLKTHLQHAQEKLTDAAGEINERLTDAKERSKKSRERRRN FT IRSHTLENNNNNGEGVDEEGGDSEDEGIEEFEERVAQTTKVLEETIRGVIDAEVRGEEL FT GRVISGLEGGVAERVRVRGVRRSQRGIGRRLRGHHGEDEEDEDGEEGVDVDVDEDEEGA FT VPFLAQFEDELRGKMEEYSTNNSYIGFYKIIHEAKHIGDEIPPPPHPSTWFAHLEDPHS FT QSQPQSHPSASTSTSTTTTRQTRPTRARPQPPSEEEDEDDDDEIAIQTERISLKCPLTL FT LPFRDPVTSTKCPHSFEREAIFTMISGSNQMVPDPRGSSGTGRAKRVRSVKCPVCEVQL FT TEFDLRSDPVLMRRVKRAEMAELRRREREMLDDGEDDQDGGDGGGGGGKRKRSGRRRGS FT AVEVDDGDSDDDSGEDDGVERIRVKRERGMSVAARIKQERAVSMVGDGDGDVEEVDMDE FT EGGGEEGGYDSMYDE" FT mRNA join(<32075..32790,32892..>33774) FT /locus_tag="An11g02530" FT exon 32075..32790 FT /locus_tag="An11g02530" FT /number=1 FT intron 32791..32891 FT /locus_tag="An11g02530" FT /number=1 FT exon 32892..33774 FT /locus_tag="An11g02530" FT /number=2 FT exon complement(34162..35127) FT /locus_tag="An11g02540" FT /number=1 FT CDS complement(34162..35127) FT /locus_tag="An11g02540" FT /note="Function: the recombinant mitochondrial FT 2-oxoglutarate/malate translocator (clone OMT103) from FT Panicum miliaceum reconstituted in liposomes efficiently FT transported malate, citrate, and 2-oxoglutarate." FT /note="Title: strong similarity to mitochondrial FT 2-oxoglutarate/malate translocator clone OMT103 - Panicum FT miliaceum" FT /note="localisation:mitochondrion" FT /db_xref="GOA:A2QVT1" FT /db_xref="InterPro:IPR001993" FT /db_xref="InterPro:IPR002067" FT /db_xref="InterPro:IPR018108" FT /db_xref="UniProtKB/TrEMBL:A2QVT1" FT /citation=[7] FT /inference="profile:PFAM:PF00153" FT /inference="similar to AA sequence:PIR:S65042" FT /protein_id="CAK48320.1" FT /translation="MASPTAAKEPQPAVDFLHHPYTRAALPFVNGGLAGMTATVVIQPI FT DMIKVRLQLAGEGVRTGPRPSAFGVARDIIASGKALDLYTGLSAGLLRQAVYTTARLGF FT FDTFSKTLNKRAEAANRSVTFAERAGAGLAAGGIAAMIGNPADLALVRMQSDGLKPPEA FT RANYRSVMDALFRISKHEGVPALWAGAFPTVIRAMALNVGQLTFFAESKAQLKKHTSLS FT TQNQTFAASAIAGFFASFLSLPFDFVKTRLQKQQKDPKTGRLPYKGVLDCARKVVQEEG FT WLRFYRGFGTYYVRIAPHALVSPPFSIRLVPLANPRPTGW" FT mRNA complement(<34162..>35127) FT /locus_tag="An11g02540" FT CDS complement(join(39734..41077,41402..41602,41650..41725, FT 41876..42057)) FT /locus_tag="An11g02550" FT /EC_number="4.1.1.49" FT /note="Catalytic activity: ATP + oxaloacetate <=> ADP + FT phosphoenolpyruvate + CO(2). -" FT /note="Complex: Homotetramer." FT /note="Pathway: the phosphoenolpyruvate FT carboxykinase(KlPck1 K. lac. or Pck1 S. cer. ) is the FT rate-limiting gluconeogenic enzyme." FT /note="Remark: the KlPCK1 gene from K. lactis restored FT PEPCK activity in a pck1 mutant of S. cerevisiae." FT /note="Similarity: the ORF encoded protein shows also FT strong similarity to the phosphoenolpyruvate carboxykinase FT from Z. japonica described in patent JP09065886-A." FT /note="Title: strong similarity to phosphoenolpyruvate FT carboxykinase KlPck1 - Kluyveromyces lactis" FT /db_xref="GOA:A2QVT2" FT /db_xref="InterPro:IPR001272" FT /db_xref="InterPro:IPR008210" FT /db_xref="InterPro:IPR013035" FT /db_xref="InterPro:IPR015590" FT /db_xref="InterPro:IPR015994" FT /db_xref="UniProtKB/TrEMBL:A2QVT2" FT /citation=[14] FT /inference="profile:COGS:COG1866" FT /inference="profile:PFAM:PF01293" FT /inference="similar to AA sequence:UniProtKB:U88575.1" FT /protein_id="CAK48321.1" FT /translation="MSPATNIHIPPVSPAEPGPLASDFFQQQLAKQRNNNYHSTSLRNM FT VAASVNRTALHPGGVQPGKGHTELEEELHEHAHIDYDRVAIIANPAVPALYEDALVYET FT GTAITSSGALTAYSGAKTGRSPSDKRIVKEETSENDVWWGPVNKPMTPDVWRINRERAV FT DYLNTRNRIYVIDGFAGWDERYRISVRVVCARAYHALFMRNMLIRPSQEELKHFHPDYV FT IYNAGSFPANRFTEGMTSATSVAINFAEKEMVILGTEYAGEMKKGVFTVLFYEMPVKHN FT VLTLHSSANEGKDGDVTVFFGLSGTGKTTLSADPNRALIGDDEHCWTDRGVFNIEGGCY FT AKCIGLSAEKEPDIFNAIRFGSVLENVVFDPISRVVNYDDSTLTENTRCAYPIEYIENA FT KIPCLSDKHPSNIILLTCDARGVLPPISKLTTEQTMFHFISGYTSKMAGTEDGVTEPQA FT TFSSCFAQPFLALHPMRYARMLADKISQHKANAWLLNTGWVGAGATTGGKRCPLKYTRA FT ILDAIHNGSLNEVEYETYDVFNLHVPKSCPGVPSELLNPKNSWTASTNFSDEVNKLAKL FT FNDNFGKYADQATPEVIAAGPVPQ" FT mRNA complement(join(<39734..41077,41402..41602,41650..41725, FT 41876..>42057)) FT /locus_tag="An11g02550" FT exon complement(39734..41077) FT /locus_tag="An11g02550" FT /number=1 FT intron complement(41078..41401) FT /locus_tag="An11g02550" FT /number=1 FT exon complement(41402..41602) FT /locus_tag="An11g02550" FT /number=2 FT intron complement(41603..41649) FT /locus_tag="An11g02550" FT /number=2 FT exon complement(41650..41725) FT /locus_tag="An11g02550" FT /number=3 FT intron complement(41726..41875) FT /locus_tag="An11g02550" FT /number=3 FT exon complement(41876..42057) FT /locus_tag="An11g02550" FT /number=4 FT CDS complement(join(45913..46114,46329..>46366)) FT /locus_tag="An11g02560" FT /product="hypothetical protein [truncated ORF]" FT /note="Remark: N-terminally truncated ORF due to the end of FT contig." FT /db_xref="UniProtKB/TrEMBL:A2QVT3" FT /protein_id="CAK48322.1" FT /translation="LIDVFLGMFMCMMSCTGLGCCLGQKRMGLSLPGDVTVNPVVVDVR FT DAVARDYGIGLARGQISRLGCLGEDDGGEEGENT" FT mRNA complement(join(<45913..46114,46329..>46366)) FT /locus_tag="An11g02560" FT exon complement(45913..46114) FT /locus_tag="An11g02560" FT /number=1 FT mat_peptide complement(45916..46083) FT /locus_tag="An11g02560" FT /product="hypothetical protein [truncated ORF]" FT sig_peptide complement(join(46084..46114,46329..>46366)) FT /locus_tag="An11g02560" FT /inference="protein motif:SignalP:2.0" FT intron complement(46115..46328) FT /locus_tag="An11g02560" FT /number=1 FT exon complement(46329..>46366) FT /locus_tag="An11g02560" FT /number=2 XX SQ Sequence 46366 BP; 11756 A; 11563 C; 11975 G; 11072 T; 0 other; gacaatagag cattcttccc gatctggctt cgtttcatgc tgcaactgtc agggttcctg 60 cagatgtgaa gttgacctct ctaacacagt tctcctgtag atctcacttg atccttactg 120 ggactagtac actcccgtct cttttgtatt tgtcctagtg aattgaccat ggctcacagt 180 tgtctatcta ctagtccctg ttggcctcct ttctacctgc cattcactgg atagtacttt 240 aaacttgctt cataacacct ttctctcatg gctagatctc ttgtcttctt tcccaactaa 300 acctgctcgc ttgtagcctt cttgcacttc ttcgtacagt caagcttctg ctacaaattg 360 cgcgtctcca ttaatctagg ctctctcgaa agtctccttg taactctctg tttcttaccc 420 cacactctct tgatttcgtc aggtctctac aatctagaat accagagact ttgatgtcat 480 tactcacctt agaaatacga cgtaccccat ccagcaatta cacggctgaa ccagaaagta 540 tatctcccag tgagtcctac tgaccgattc acccttcagc catcacttac acctttttag 600 cgatttctcg ggctagcaag atgacgcctc ccgaagccgc tgagatggac tctattaacc 660 tgatcgccag cgacatgaag gagctggtcc gaaaaataca agatctacgc cacatcggaa 720 tcgaggacaa gatgattgtg cttccaaaaa tctgcgtcat tggtgaccag agtgccggta 780 aaagctcttt gatcgaggga atgagcgaga tcaaggtgcc acgaagcgca gggacctgta 840 ccagatgtcc catggagatc aatctctgtg atggggagcc tgaccagccc tggacttgca 900 aggtcttctt gtcgcggaag tacatgtttg acgcctctaa gaagattggc aaaatttcga 960 aaaagtccca gtccctcggg ccttgggtgg agcaagagca acaggaagat gagcttttca 1020 cgacactgac aaacaagctc gacctcgaag aagtcattag atgggcgcag ctcgccatcc 1080 tgaatccagg ccggccatca agcgaatact tgccggggca aaacagcgaa acagatcctg 1140 gttattgtca ggtaaaattc tcgcccaacg tcgtccgact agatattacg gctccaggct 1200 ttcctagcct atcattctac gacttacctg gtgtcatcag ccaagccgaa cacgaagaag 1260 agcgctatct tgtctttctg gtcgagaacc ttgtcaagca ttacattctg cagcaacact 1320 gtatcgtcct gttgacattg ccgatgacga acgatgcaac taattcgagc gcggcacgaa 1380 ttatgcaaga gatccgtggg gcgaatgcta gaacaatggg cgttctaacg aaacccgacc 1440 gcgtacagac cggggaatca tttgcccagt gggtcgaaat acttgaaggg gacaagtttt 1500 cgcttggcca tgggtacttc gtcgttcgta acaatcccga cccggctgta gagcactatg 1560 tggctcggga agaagaggat gctttcttcg caagcccgcc ctgggcaaca gatttggctc 1620 tctatcaaga gaagtttggg acacgccgat tacaaacggc tctctcctcc ctccttcttg 1680 aacagattca aggatgttta ccggacttta ttgagaagat aaacgccaaa gcagatcgaa 1740 tcgagaccga acttcggact cttccagatc ccccctccgc aaacgttcca tatattattt 1800 gcggcaagct gaatcaactg aaggatcaga tccgcgctca cattgatggc gggtcagcaa 1860 attaccctct acagaagatt tggtcgcata ttgccatgga tttcaagcga gctctgatca 1920 agactcggcc cactgtgcac ttgctctctt caagtgataa gttccctggt ccgacgggcc 1980 gcgatgcgga gggaagcgat tcagactgcg agatgacaac ggtcccacag ccggccaaac 2040 gcaagtcacc tggtgagcct ggaaatattt cagtcgcacc agaagcgaga taacagccaa 2100 attcagcaac aagactgacc ggaaatggat tgtactcgac agaacatttc gacaagttca 2160 acgccccggc cctgacgttt acatgggaaa tgattcgcga gataaacgag gattcgtatc 2220 gagctggact gccagaccag acggacccaa aagccattga gatcatgaac cagatgagcg 2280 taaagcactg gtacgaccca ctgtcagtgt tcctggttgc cacccatcga cttgtccggg 2340 acatgctgca caagcagctg gatgaagtct ttctgcaata ccatcagacg ggcttatatc 2400 gagaactcaa gagaatcatt gaaggctttt tgtataagct acgggcagcc cactttgaac 2460 acgcacagga aaactttaat atcgaataca ataaaccctt cacattggca ctttcggcat 2520 tggaccaatc aatcaagtct gcttacattt ttcttgcgga aaagcgtcga tttgctcgcg 2580 caagctctta cctcgatgct cagggaaagt accctcgagg agacgcccga cgggaagctg 2640 agcttaaaaa gcttacagat gtcgagctgg ggcgcgacca gttctcgcag gagctgacca 2700 tgatggcggt aagttggttt catggcaaac tcttggctct ttatagacta actgtcctgg 2760 ctagacgagt cgaggatact acgacttggc gagttcgcgg tttattgatt cgatttgcca 2820 gagcgtgcac actaaattgt tcgcaaaatg tcgtgatgac ctcataaagg agattgaaag 2880 agagctttgt atcttcgatg aaaacggtac gtttctctcc atctatcttg cacatggtag 2940 atactaagac gtcgtcttgc tcccagcact ggaacgttgt ttagaactta tggaggagga 3000 ccctgaccgc cagagacgcc gccaattcct tctcagagag aaggagcgaa tcgataaggc 3060 ccaggagtgg ctaaagctgg cgaggaagga ggacgaccag gaagacccgt tcgataatgt 3120 gagaatcaag tcccagcctc ccgacgattg gactacttga ttccggcttg gcgagacttg 3180 tgtgagcatt tgtctgtccg cagtgcgctg tgacaacaga gtctacttgg gcgtcaattg 3240 tgatagagcg gtggctggac catgtgagtg gattgttgga caaagttgca gttgaagctg 3300 gaacatcata atgatgaatg gatggattga ccgcaagcat cgaggcgggg tagggaaccc 3360 cactttgatg ccctaagccc taaaccctgc ttgcgatagg ctcgaatggt gtatgacagc 3420 atgtacccaa tggaaaagga aagaggttag atagaatgat tacaagctat tgaatgcaat 3480 tcaatgggaa catttggtac tttctactag actcgcgcaa tgatgataaa caggaggccg 3540 agtccaaaga acagacgatt acttaaggac tggctgggcg gggggaagct gcccctcgcg 3600 gtgcccaatg aggatcgccg gcggcgactc ccgcccaaaa ttctcgttcc ctccgacttc 3660 agcccaccat cttgtgtgtc atcgatcgat ccctccactt acctttcttt cccttctcat 3720 cgtcttgttc ccacggtgat tgagaccgag caattacccc ccgtccatca ccatggctga 3780 taacaatgct gttaaggagg ccgaggcctc catggccaac ctcctcctcg atgaggtgac 3840 cggcgagaag gtctccaagt ccgagttgaa gagacgccag aagaaccgtg agaaggaagc 3900 caagaagaag gagaaggagg ccgctgctcc tcccaaggcc gagaagaaga cttccgccga 3960 ggatgaggag gccaacctca cccccaacgt gagtcatttt cttcctattc gtcccttggg 4020 gggcgcttct ttgtgtgctg tcgggggatc cattgtcgca tctttgctaa cattcccgct 4080 catctcctct tctacagcaa tacttcgaga tccgcagcaa gagaatcaac aagctgcgcg 4140 agaccaagaa ccccgacccc tacccccaca agttccaggt taccgatgat ctgcgcaagt 4200 acctcactga ttacgagggt ctcgccaagg gcgagcagaa gcccgaggtc gccgtccgca 4260 tcgccggtcg tatctacact aagcgtgctt ccggcgccaa gctgatcttc tacgatatcc 4320 gcgccgaggg tgtcaaggtc caggtcgtcg ctcaggctca gcacgccact ggcggcgtgc 4380 ctttcgaggc tcagcacgag cacctccgcc gtggtgacat cgtcggtatc gtcggtttcc 4440 ccggccgtac cagccccaag aaccgtgccg acggtgagct gtccatcttc gctacggagg 4500 tggtccttct ttctccctgc ttgcacgcca tcccgtccga gcacttcggt ctgcaggaca 4560 aggagcagcg cttccgccag cgctacctgg atttgatcat gaacgacaag tcccgcaacg 4620 tcttcgtcac ccgttccaag attgtgcgct acatccgcaa cttcttcgac aaccgcgact 4680 tcgtcgaagt tgagactccc atgatgaacg ccatcgctgg tggtgccacc gccaagccct 4740 tcgttactca ccacaacgac ctcgacatga acctgttcat gcgtgttgct cccgagctgt 4800 acctgaagat gctgatcgtc ggtggtctcg agcgtgtgta cgagcttggt cgccagttcc 4860 gtaacgaggg tattgacctc actcacaacc ccgaattcac cacctgcgag ttctactggg 4920 cctacgccga tgtctacgat gtcatgaacc tgaccgagga gctggtttcc ggtctcgtga 4980 agcacatcac cggtggttac gagaccacct tccacaccca gtctggcgag acctacaacg 5040 tcaactggaa ggccccctgg cgccgcgtgg agatgatccc cgcccttgag gaggccactg 5100 gcgagaagtt ccctccgggt gaccagctcc acaccgccga gaccggcgag ttcctcaagc 5160 gcgtgctcaa gaagaccggt gttgagtgct ctcccccgat gaccaacgct cgcatgctcg 5220 acaagctggt tggtgagttc atcgaggaga cctgcgtcaa ccccaccttc atcactggcc 5280 acccccagat gatgtctcct ctggccaagt accaccgcca gaacgtcggt ctgtgcgagc 5340 gtttcgaggc tttcgtctgc aagaaggaga ttgtcaacgc ctacaccgag ttgaacgatc 5400 cgttcgacca gcgcctgcgt ttcgaggagc aggctcgcca gaaggaccag ggtgacgacg 5460 aggcgcagat catcgatgag aacttctgta ccagcttgga atacggcctg cctcccactg 5520 gtggttgggg tatgggtatt gaccggttgg tcatgttcct gacggacaac tacagcatca 5580 aggaggtgct ggccttcccc ttcatgaagg aggacaagac tgcacatgat accaagcccg 5640 ccgcggaggt ggttggcatt gagcctcagc ctgaggaggg tatcggtaag tccaccacct 5700 tttattcttc ctaggacaag agaactttat agctaactag tggattacag cccacaaata 5760 gataaatgtg atgaactgct tattagatgt tagttttctc tgatgactag ttgcatggta 5820 ctcggatgtc aatgaagaaa tgcataaaat gataatagat gccacagatg tagtaaatat 5880 ctttaccctc cctctattat atacccacct catgaccctt atagtattta tcttaagaaa 5940 gtaacatacc ccccgtgctg aataataaaa aagaagagaa tggcttgttg aaatccgccg 6000 caagcaggac aagagtggga ttcgaaccca cgcccctttc gggaccgcag tcaggtgacc 6060 ctggctaacg gtgccttaga cccctcggcc atcttgtcta ctgttggcag aggggttaaa 6120 gcggataggg aagattggtt gcgggatttt agacctttgt ctttgccttg tcggtgtgag 6180 tcatgagatg acaaaaaggt gatttgattg ttatgtcgtc aggttcccct cgggatgaga 6240 tagttgatgt agagttgacg aggagggcag gggtaccgga tgtggtttag cgccgggaga 6300 tgataaacgc aggatccact acattggtat aaagcggtac accgactaac tccaaaatac 6360 tgccacatag cgccgccaat tttaaccgaa tctcagatga ggtttctggg aactgtatgt 6420 tcctaaaacc cgctaaatcc gaggtttttt caacgaggtt cactagtttc tgccgcttat 6480 ggcggtcaag gaagcggtaa gagtaattgc catcactact gacatattac ctcccgctat 6540 attgatgcct taggcagata tacattgggt atactagtgg tcatggggag cattgtgtag 6600 acgtgttaag taattcttct tgggttagat ggggggtagt aagtgcgcta cgattattga 6660 gcagataatg cattctgata aagctgtaat gtgctcatat caaagtgggc atttagacga 6720 tgtttctcac tgagtaggag tttgtctgaa cgagatctac aaagtagtag tttgctagta 6780 tcataaaaca acaatgaaag cttggaaaat aatatgagta ttactagcac cgaacagttc 6840 tttcttgatg agttactgtc actctacttc gtagttgtgg taatcagtag ggtagataca 6900 agccttagcc ttatcagcca gtgtcgaatc cagtttgctc tctagtagtt gggttgaagc 6960 gtaaggatga taagtgtaaa atgcactgcg ctagcttcca acgataaagc ataaatctat 7020 ttatggggca gtttccgtcg gaggattatg gtgatgatgg tccggggctt tccgtaggga 7080 agttccgata aagatcgata gagatactgg tagtaatact atgcttggcc tgtatatatt 7140 gtctttttcc taagtatgcc cacaactatt tcacgaattt tctcaattct agaaaaggct 7200 tcctttcgca gtctattgta tgcgttcaga gggactggta tttgatatct acctattgtc 7260 aacttctttg ctaagtgaga aactattaat agtactggct actgtttgca ttggtctcta 7320 tatatccacc tattaagtag aaaggcaatt gtaaattccg taaggattca catccgtggt 7380 ctgtcaaccc agttactgcc agtggctgtg tgtcatattc actggtcatg ggacatgata 7440 gttactggaa tattcctcca agtctagcaa gcccgatgtt caatttccct tcagctataa 7500 caaactgaac tgtgagcccc aacggacttg tcgcgcatag gaactccaaa ctcccgagag 7560 cataactcaa tcacaccggc atttccctgc gcaacagctg tacatctcca caatttcttt 7620 cgaagataag tattctagaa gacaaagaag atgtatatat acttcggaga attatctact 7680 catctcgacc actagtactg actattacag ccacatccag ctagtaccga gccattacca 7740 gtgagacacc tagtttcact actcgaactg ccatggattc ccggtctaca accgccccaa 7800 acgacacgac cgcagaccag agcccagtct cagaaatcca cactgagttc cggtacatag 7860 aagcctacga agatgtctgc gacagttgcg aactcttcaa catgcagaat gccatgtcac 7920 agtgcaaatc atgtggatgg cgagaatgtc gtgcgtgcac gattgaaact ggtggccgtc 7980 gatcccatca gttccaaggc aggagacatt tctcccctgt cgatatatcg gagttgcgga 8040 cccaggcggc gattgatcac gaacgcagag tggccagact agggggatgg atgtcaatga 8100 gggggttgtc aagacagagg ggccatgcca gggggtggag atacagtaga aggaggagag 8160 gagaacagat tggaggatgg ggaaggagaa acggacgagg ccaccgtgga aatcgccaac 8220 gtggtcaaga accagcgcct ggagctgcgc ctgctcctgc tccgtccccg gcagcttctc 8280 ctaacactgg ggaagcagac ttggacggtg cccgagctcc cgagacagcg gagggtgcgg 8340 agatgctgta tgctttgggt cttgaagact ctgctagtcg cagaagtgaa agtggtaggt 8400 gacagataca gtaggtctaa aacatagctc tttcttacag cgtttatagg gtccaccacc 8460 tctgaggaag agagacaaac tagacatgct tcctgtctca tcctggcaaa acgtgctcgc 8520 gaacaattcg aaacccagca gacagacagg gcaactgagg agtgtgtcac atgaaataga 8580 taactatctt ttgaagtgct gttattcgac tactgctcca gcaacgaact tccgcccttt 8640 ggcttttcac catgtgtcat ggtgccacaa caccattttc gttcattgct atgaaatgtc 8700 gttggctatt ctctgtctta atttgctcgc actctgtgtg tggaacagtt gggcagaagg 8760 aaagatatgc ctgtgcgaga gacgagagcc ggccttcaac acaggcataa tattcggaaa 8820 gaggtaggcg ccgacttcct ccgtcattct ccattatgct gttgcccgat gccagcagaa 8880 tttggattat gactactacg attgcagtat taagctaatc cggcagagac aaattcagtg 8940 gtacgtgatc atattataca aatacgtgaa gtagagattt tagtagacat acagggccac 9000 tctgtggcag tataatacat gtaggatgta gtccagaact cctgtctgtt cgtcatattt 9060 ggcccttata tcctccgggg cgcatgggcc gcggcattgg cgagagcctg tccacgggcc 9120 ttggctgcca tctgaagcag cttagccgtc ctagacgggt gccagatacg gcttcccagg 9180 acaagcaccc aggtaagaag gaaaagactt cccgcctggt gggcagaggc caaaggcgtg 9240 ggaacaaggt aaagaagcgt cgagataccc agaccaacct gcatgcaagc gaaagcgacc 9300 acaccgtgga cacccttctt cgcagcgggg ggcaaaaggc gtttcatggt gggggatccg 9360 cgagtgtagg ccaacagagc catgatgctc gtgaaggtag ttatggccag agcgcggtgg 9420 tccagttgca ccagggaagg attctccagc atgtttctcc accacaggtc tgatctgtcc 9480 tcgtggcgag agtaccgttc atcaaacaat tcagacttag gaggagccag gccattaccc 9540 atgaatggga actcgttata gatgagacca gcatccaggc cagcgaccag ggcacccgac 9600 atggcagtca cgaaaaccaa tgcagccaaa gcggcgacgg agcgacggaa gatcttgagc 9660 ttagggtcac ggagcgcgtc aagaagcttg attccagcct ccgggtcggc gagcaatcgg 9720 tgggagcgca ggatagcaag tccgttccag agcatagcag tatagcagac gaaagccgca 9780 cccagatgcg ctgtcagacg gtactggctg acacgagggt ggctgccggg agcgaaaaga 9840 tcatccttca ggccagactt gaccatccac cagccgataa aaccttggaa tccgatcaag 9900 cctgcgatac cagcgagacg cagagccata ggcttgctaa cctttttcgc agcaacgaag 9960 tatgcggccg ggaggacgaa cgacaagccg acaaagcggc cccagagacg gtggatccat 10020 tccatgtagt aaatcgactt gaattcggag agggtcatat gcgggttcaa aagctgaaat 10080 tcgggggagg cacggtactt ggagaattct gactcccagt cttcggcgtt catggggggg 10140 agggatccgg tgacagggcg ccattcggtg atactcagac tataaaatgg ctgcgttagc 10200 attggtccga aatatagcaa tggatggaag gaccataccc tgattcagtc aacctggtaa 10260 ggccgccaaa aactacaatg ccaaacacgc tggccgcgct ggccagtagc cagtaggcca 10320 ctttcttatc gctcacatcc gggaagctcg atttggcttt cgcggcttct ccctgggcag 10380 caattgcctc cgccgttgct gatccggagg cacttctttt caggctagac gcaaaaagct 10440 ttctggccct cgactgcagg gcagagttgg ctctgctgtt ggagttctgg gtgaagggca 10500 gggcggagaa ttgtctgcgg aaggcggatt tagtcgcgtg attctgagtg cggaccaaac 10560 attggcggca ggtgaagagc tccctcgata gccggggaga caagcttcgc agcaagggca 10620 cggaaggccc caaggatgcc atgatgggcg gatgaagaga gaatgaagct gttcaaggct 10680 tgccaggcca gaatttctgg ttgaaactcg gcgagtctcg cgttcggaag cccgaaggcc 10740 gagaccattc cagccaatca gagcacgcca atttgttgcc gatcgatcag cccatacact 10800 ctatacattc tacctcgatc tctctctctt tctctctctc tctctgtcta accccttcta 10860 ctccaaacat ctgtctatga tggtggtggc tattctgcca catcatatca cgttcaagtc 10920 gtacaacctc tcgaccaatc tgaggtgact cggcatgcag gcgtgaggga caccggtgct 10980 tgcttcaagc cgtctggaag gtcatggcct cagttagtga tcaataacct gttatagcat 11040 atactctaca ggactattca gatttccttt ttttttggat gccgcacaca tggtctgttt 11100 tcccctcatg acagtgctgt ctacatatgt tcactcctgt ggcacgtcac gaacaattgt 11160 tcggccgaac tactctcgcg tctggaagcc ataacttagc atcgaccgat aaagcttgtt 11220 tccacacact ggcgcgtttc tgtgacatag tgatggctat ctataatacc acacatgatg 11280 ctgaggattt atcgaactaa aggcgaaata cacctttggc cagccaaaaa agcacagcca 11340 cttcgctaag gccagtctcg gtgcgagaaa tggctccaag catgtaaagc agattgcata 11400 ccaatgggta acttcactgt tactaggcaa ggatcactac tgttctggtg tacctgaagt 11460 attcaaggat gagggactag gaacggacta gtctcagttg ttcgtttctc cgctgctgat 11520 cattaccttg agaatgtgta catcaaagtt gttcactaat tcgcctcgga cttcgcaaat 11580 ggttcgtgaa ggtgtgatag tatcactgcg gggtcctgca acatcaaggc atcctttttc 11640 ccagattatc tcattctcct cttttctctc ggtatacccg gggccccgca caagtggggc 11700 cgatgcaggg tatcagacac taaacagaca cgcagcagga tatcattcaa cccgtctata 11760 cgagtacgac gtttggtaat cggctgcaat cagaccgagc tgtatttctc gcccacagta 11820 gtggaggagg ccaaagcttc cacgttcctg ggactactca gctcgttgca aagaatccca 11880 tgatcacact ttagtccggt cccctcgtca gctccatgca ttaccgagca agtattcatc 11940 caaagatctg ctgcctgact gcttcatttc ggctcagaat tgtaccgagt cgcttgactc 12000 ctcatcagac tcgtcagagc acaatgggtg gatggtctat cagatattta tatagtatga 12060 tgtatgattc tcgagattca taccattctc accaggaacg ggatcaaacc acataaaacg 12120 aggatgcatt tatcgtatcg tttaataaac actgctttac ttgttcagag tgtgttcgct 12180 accgggacta atgaccaagt cgaacctgac atcgattatg gcagctttca aaatccctca 12240 tccaatgtgc gaccacgttt ccgctactgg gtgaatgatg catccatgaa cctgagcgtg 12300 gtagcagaag acgtaaaggc catgggtaaa gctggggcag gtgggcttga gttactcggt 12360 tattatctgt atggagattc gtcgaatcta gatggacaac tacaatgccc cctgcaaaca 12420 gattggacta tattcggttt tggaagccct gcctggagta tgccctgctg cagcccatga 12480 ttctgctcaa gtgatatact aatatgttaa ctagaggatc tagtcgacac tgtcctgacg 12540 gcggcaaaag aatgtgatct actcgtggac ttggccattg ggccaaacca aggtgctggt 12600 gttccggcgc cctacaacga tggtggcctt ttgtgggatt tggccgggtt caactcgaca 12660 ttgtccagcg acgaaggctt tgatggaatt gtgtgcgggc cctctgattg cagctgttac 12720 cgcccaggtc aactcgacca gtccaagcaa tgatacatac aaaatactag cggaaagctc 12780 gttactggac gtcacaaatc tcgtcagctc caatgggcat cttcaggtca aagtaaacga 12840 tactgcagga ggttctaagt atcttttcac ctattatttg gttcattccg aatatcgtga 12900 ggtccagagt cctgctgatg ttacggccgc tgtccctcaa tcgcccgtga cgacttaccc 12960 gcagaacggg tcatgggttg tggatcattt ctcttcccaa ggcgcgttgg cagttgtaga 13020 cttttggaga cagtcattgc tggacagcga gacaggcgca ctgattcgtg aagtgggcaa 13080 ttacctctgg gaagatagcc aggagttcac cgtctccaca ttctggactc cgcgcctcca 13140 agaggtgttc caagccaacc gaggctacag tatcaacaga ttcattccac ttctgattgg 13200 atctggaggc ggatcgattc cagatattac ctatgttact gatgagcttg atgcaggtgc 13260 cagtcataca atggactatc agcaaacagt tcgtgtgcct cctcccatat gaggaaggag 13320 ttaaacgctg acttgagtag ctcacagaac tgaacgccga gtatctcacg tctttaaaac 13380 aatggagcaa tgaccttggt atccaattct ccgcacaggt agtttacaat ctgcctatgg 13440 acatgcttgc caacgtaccc tacgtcaacg gtcccgagtg cgagacacta ggtttcagcg 13500 ataatattga cagctacagg caatttgcag gtcccgcgca tcttgctggg aagcgcatta 13560 tcaccaatga ggctggcgca gagttgtcga aagtctacca ggaatccata cctgagctct 13620 tgtggaccct gaaacgttct tttgccggct ccgtcaacca gtttgtgctt cacggatacc 13680 caaactctgg aaattacgga aacacaacgt ggcccgggtt tacaacattc tcgtatctgt 13740 tttcagaaat gcatggtcct cgtcagccgg cttttgctta ttacagtgat tttctcgatt 13800 ggctctcccg gaaccagttc gtggaacaga caggtatccc taaggtggac attgcctttt 13860 ggtcgaagtc taccacatac aagactgtgc caactgttta cagtcctgtc gatttacaga 13920 gcgcaggtaa gcagctccac cctggaccgg agggtttatg atgcttagct aaagtctggt 13980 tcgcaggcta tacatatgaa tacctaagcc ctgacaactt tgcgctaccc ggggcgttcg 14040 tctccaatgg cacttttgca cctaaccagc aggccttcaa agccctcgtt gtgcgagcaa 14100 acgagaccct gacagcgtct ggagttgcga aacttgttga atacgctcat tccaagctcc 14160 cgattatctt ctccggtgga ctgccatcga acttcagcgg gtacaatcca gaagctgcaa 14220 gtctagccgt cagcacaatt aagaacctaa cttcttcaaa taacgttcac atcgtaccgt 14280 atgacaacct ggcggcaaca ctcagatctc taggcatact tccgcgtacg tccgtgagtg 14340 cgaaccgcac ctggtacacc acttggcggc acgatacaaa gacacttacg gactatgtct 14400 atgtgtacaa tgatgcagcc ggtgttccat ttggaggtgg tatttcatca ggaacaatat 14460 ccttcgagac aacgggaacg cccttcctct acgatacctg gtccggtgat atcagcgcct 14520 tgtccatcta tcagaaatcg gagaaccatg ttacaatacc tctgactctg gccggaaacc 14580 agtccgtaat catcggtttc cacaagaact ttcagccaac tcttcactta cagaatacaa 14640 caggcggaat cctaggagca actgggaatg ccacatccct caccgttctt agatccgtcg 14700 atcaggaatc tcgggacatc tatctttcga atggcaagtc cgtgacccta ggcccgatgc 14760 taacgcctac aatcacgctt ggcaactgga cactgatagt cgagtcatgg acggcgcctt 14820 cggaccttta caacgtcgag ttggggccga aacgcactaa ccaaacgttt gatcttccga 14880 ctctactgcc ctggaaccag gtatcggcgt ctctagccaa tgtttctgga atcggatact 14940 actcgacaac gttcgactgg cctccgcagg ctaccaatgg cacggtatcc ggcgcgataa 15000 tcgatgttgg gcccattgtg cacacggcac gcgtcaccgt aaatggacac gtgctgccac 15060 cgggagaaat cacttgggca aagtgggata ttgggtattt ccttcgacgg ggacagaata 15120 cggtggaggt agttgttagt acccctctgg gcaatgtgct acggacatac tgggataaat 15180 tggagacgag tgggaaactt gccactgccg ttgtcccgtc gcccccggat gaggcagact 15240 acggattgat tgctccagtg agaattattc cttatcggaa agaccaggtt gcttagttct 15300 cagaatgcgt attgtgccat ctgcgggtaa cagctatgct acgcctgtca agtgcctacc 15360 atgtccatag ctaatcagat cttcgaaatc ccgcttgata tcgatatcat gcttgttaat 15420 agcagacaat atacacaacc aaacacattt atacataacc caagtcaact tccagcctca 15480 cgcagcacca tttttcaacc tctccgccac ctcaacatac gacccatgcc tcacctcctc 15540 cacaatccca accttcttcg gcgcccaccc caacaccctc atcgccttcc ccccagaagc 15600 cctattctcc gtactcaaaa acctagcaaa gaactccccc cacaccccct tggcctcctc 15660 aaacccaacc aacccaacct caacccccaa aacatccgcc atggccctcc ccaactcccc 15720 aaacgtcact ccccactccg aacacccatt aaacacctcc ccagcaccgg ccctctccgc 15780 agcaagcaaa tacaagtcgg ccgcatcctc gacatgcacc gcagacgtaa ccacctcctc 15840 cgcctccttc acaaccttca cctccttctt ccccccatca ccaccattcc aaaacatccc 15900 catgaacaac cccaccccac tccctccccg tccatacaca aacggcggca accgaatcac 15960 aataaccctt acccctttct cctcccacca cctcaggttc ttcctctcag agacaatccg 16020 ctcattcagc gccttccctt cctcccatag tgccgagttc tcgtccgtct ctgttcccgt 16080 agcagcaact accaatgatc cggaggtcac aacaagtggc ttgttagtac ccactaatcc 16140 ctcggcgatg gcggtgacgg cttcgtcgtc gatacggatg cgttcttcgt atgggaggct 16200 gtagttccct gccatggggt ccgccaggtg gatgactata tctgcttttt ggctttgctc 16260 acggaggacg gagtgtgtgg tgagatcacc acggatcgga acggcgccga gggaggtgat 16320 tttggcgtcg ctttcgggac tgcgtgagag ggagtggatg gtgtagttct tggatagagc 16380 gtgggttgtg atggcgtgtc cgaggtagcc gcttccgccg gttaggaaga tgaggggcat 16440 attggaagag tttcttcttc tgatcgatat ttgattggat tagtatggtg ttttggactg 16500 ttgcttgttg gtttctggtg tatggtggga ggttatatat gtagtatctt cgaggtatat 16560 cggggttaag ggggttaact ccggagagga tccggagttt aggatgaaat gatacacgat 16620 gggggcgatt ggttagtagg ggacgtgagt gcgcatacgg gatagaaggg atccgaggag 16680 tcgttatgct gggatgagtg aataatacgc ctatctctag agagcattat gggtcgaggg 16740 ggaagatgat agggcttttt ataggacaga tagagaacaa gctcatcagg tcatgtgtta 16800 aaggctctag tatactctac taacaagcgc aacatgcaat ctcctagcag cctcctatat 16860 ctctaccaat tagaaaggaa cctcttcccc tctccaactg atgaaccgac ctccgactgt 16920 ttccctcgtg gcgcttgcaa tctagtctac tcagtatcac accccaatat ataagaagta 16980 caaataagaa tatagactta ccaacttcac caaagcctcc gcacactcct tcggctccgc 17040 aaacgcctct tccaacccaa tactcttcgc acacgcattc cccatctcag tcttgacgaa 17100 cctacgcatt tcatatcagt accccaacct cctaagcaca agatagtaag ctcaccccgg 17160 atgaaccatg aaacaaacca tctcctcatt ctcaacatgc attttcctcg tcacccagtt 17220 actggcagcc ttactaaccc cgtatgcagc cccgggaaag aattcctcct cgagaccgcc 17280 gatactcccc aggaagctac taacactgac aaacatcggc ttcgtgctct tcttcagcat 17340 gtcatacaca ccctggaaga ggcggattgt gccaagcgtg ttcacgtcca agtgcgattg 17400 cacagtagag agagggatgt tgtcgacgcg gtgggtggcg tcgttgtagt accctgcgtt 17460 ggaaatcacg gtgtcgatgt gcgtgatgtt gtgtttcgat ttgagggttt cgatggctgt 17520 agtaattgag gtggtggatt ggatgtcgag gggaaggagg atgagggttg aggtggggga 17580 tgttggtggg gggttagtat agagagagtt cgtggtgggg ttgcgcatgg tagcgatcac 17640 agtggtgttt gggaggagca ggagagtttg ggtgagggcg aggccaatcc ctggattatt 17700 ttgtgggtaa gctggacgaa gagggtggtg tggtatgggg atgagaataa gaaaagtggt 17760 gtgtacctct gctggccccg gtgatgaggt agatggttgg ggatgacatt gtgggatgtg 17820 agtttgcgtg ggattggtga tgcttgatgt ggatggatac agaattgaga tgtagaaact 17880 aaatgaatat cttgaggtgt gaatgtatag gagagtaatg gggtctgtct ggtggaggat 17940 aagcgatgca tttatagtta ttcgttttgg ggctagctaa gctgagacta gggcaagaaa 18000 ggagctgacg agtcgtgact tgtggtggga tacgagcttt ccattcctgg catagcagta 18060 cagtctctcg ctaaaccctg ttacaggcct gggtatatag agcactggat gatacaattc 18120 tgattactga ctgttcctag accatagttg tatgtttcag gccccgcaaa tcagcttcac 18180 cctaagaatt aagttgtatc agtattcgtc cattccatat actactaaat catatgtgat 18240 atggcattgt tttcttgccg tcgttctcaa tcgtttactg tctactagtt attagactcc 18300 gcgcatgtcc tgatagatgc agaagtgatt ttagctgcga tgaagcccac tttctgtata 18360 ataagggtct tgctcggtct cggttaggga ctatcgcaag ccttaagagg atgagactgc 18420 ttggcctctt gaatagtcat tgaattctac tatttgatta tggtaagaaa atgcgttcgc 18480 atgctcttca tatcgctgct ctctgtacga gtaaagcagc ataattgcgg ggaaagcctc 18540 tatagtctgc tgatgagtaa actcctctcc tcttactcga gctttacttc tgtactctga 18600 gtttcaagta aacgtcctct gtaggtacaa ttgaaccctt cccagccctg tccctcgatg 18660 ccttgagtga atctgaagat tacgaatgaa tttatcccgg aacctgcaag aatgtgccac 18720 tcccggagat gattgaaatg tgactgacta aattagaaag ggttccccct gaacgcattg 18780 gaattacata cctgaagcgg agtaatgtat ctttcaaaat gtgctgtggc gtggccctcg 18840 gcgtctgagt gacaatgcac gatagtgcaa attgttcgaa cgctattgtt ctgaaattta 18900 atctcctcga aattgaaagg atcccaaaat ttccagatcc gtacttgttg taaacttggg 18960 aactggacag tgtctaagcc atcaggtttg cggcaatagt ctttcagtgt agcgatcttg 19020 atgtatgttg cgtatatatt ccggcgtgct tctgggattt tatcaaggag gtccagaaca 19080 tccctacaag tacttgggga atgacagggc atgggatttc tccatagcca acgcattgcc 19140 tctgagaacc ataatttgct gacgagggcg caagaaagga gttgactaca cgatcgtttg 19200 tcgtatgaat agaagcacgc gaagacctga ctcaagattt cgggaatcgc aagcgcacgc 19260 tgaacggctg aaatattaag gtgctcattg ttcagagcca tttccaggtt gtacaatgtg 19320 acaaactgtc agtatggaca aatgtaagct aataattttt ggagattcta ggcgctccgt 19380 aggtgatacc ttctatcgcc acttggctga tatgaattgt ccaggaccgg gggaagccac 19440 agataaatga acaagtcaat aaaatagtag aagggttata aggaagtaat catagaagta 19500 agttgcagat ttctggacaa agtagcatcc acgatggtct ttatcataaa gaatgcctga 19560 tgacaagtgt gaattggtat agaactcagg tcagacagac aatgaactaa ataactatat 19620 agaacagttc atacagctag gcacccgctc tgctgcctgc aagaaaacat ccctttcatt 19680 cctcgcagag atgacctttt tccggggatg tagagatcct gatagatacg atcaaccttg 19740 ccccgtttcc gatgtcctaa gtggactcag ccacataatt gtacacaaat aagaaagaaa 19800 aagtagtacc tgatgctgct cggacacaat tggatgtcaa gaaaagatat gtgatctaat 19860 tccgtagttc ctggcgattc acctgcaggt gaacatccct atcgttgcct taggcagaaa 19920 catatttagc tccatttcgg gtctagcgcc accagctccg aggccattcc aagatccaga 19980 ctcccttatc tcaaagacca ctccaactgc acaacgccat tacctccgcg tgctggaaaa 20040 tgtcctacgc cgttgaaacg aagaagcgca agtttcatcg agttctcgag tccctaacca 20100 aaccgtcaac ctccgactca acaaaatcag ccaccgccga agcgcctaca acagctcgag 20160 acgcatcgaa gaagaaagcc cgtctagatg cgcccaactt ctcacttgca cgaaattcac 20220 ttctaaaggt cgcacgcccc agctccagag actcttcggt atcgtcaacc tcgcgaccga 20280 gctttgttcc ttgggatcgc gaacgttttc tcgagcgatt ggaaaccttt cgtcgcgtcg 20340 acagatgggc acccaaaccg tcagcaatta gtgaggtaga atgggccaag cgcggctggg 20400 tatgtacgga tgtggcccgg gtaacatgtg ctgggaactg tggtgggtcg gttgttgtca 20460 agcttccgga tgagctggac gagttggatg ggttcgatgc cgacaaggtg caagagagga 20520 aggaagttcg tgagttttcc aattgccgtg tctgcttcgt gcttctaatg taaatcagga 20580 gccaagcttg tagatgaata cgtggaacga ctggtcaagg ggcacggaga gacttgtcca 20640 tggaggaaca agggctgtga tggtgtgttt tctgatattt gtggttgcca tttcgtgagc 20700 tgattgttac agctactatt catcgattgc cgctagcaaa ccccgacata gccatttctg 20760 gcctcgaaaa gcgatactca aacctcatca agatggccga tcaattgccg gcagcagacg 20820 tcatccacac gcccgagtcc ttcgatatcg aagcactcat taagatactt ccagcgagct 20880 ttaacggccc cggagaaagt acgcgcatgg aaagcattga gaacaacact gagggtgaaa 20940 acgggaaaga gaacgcacat aactctgagc ctgagccgtt tgttcctagg aacgctttca 21000 tattggcatt cttcggctgg gactctgtcc cggacgggac agctggtttg gtcggctgta 21060 gcgtgtgctt ccggagattg ggcctgtgga tgtacaaacc aaaggccaac ggggatgagg 21120 ctctttacga ctctttggaa gtggtgaacg agcatatgga ctactgtcct tgggtgaatg 21180 ggaaggctca gagtggaaca ggacgggcca ccgagaaact agaaggccta cgttccggct 21240 gggagctgct gggccaggca ctcaatgtgc gccatcgtcg actgaatcgg tcgaccacct 21300 cgggagacag tcgtgctgtc tctgaggtac catccacgga tgagcccgtg gtggacgatg 21360 tgaacccaga agttaaaaag gccagtgacc gggaatggtg ggccaagtta cgccgcatgc 21420 gacaggtctt gaacgtcagt tcgcctagga agaagccgac ttcgcagtga tatttttcat 21480 cattctgtac ttctgcacat gatactcctc atctggttgt taatgcagcg tggcgtttgg 21540 gcatcatgtc tatcttctcg atatccttca ttcctacatt agttattgct atagcgagcc 21600 tttgtcatcc gcctcgataa attagaatac agccatactc aatcagagaa agatcggaga 21660 acaaaagtta tcatttactc aacgacataa gaagcattgc tttgaagcca gatgcacaac 21720 ccgccaagcg taattaagct gaagattata agcacccatt gaatctgctc tctctttccc 21780 ttccgcctgt acatctccca gcccggtcct gagcgccctg gcaaaggcag aaaagaaaca 21840 acctctgcat ctgccattac tttcgatgcc aggtcagcag gaaggttgcc agcataagga 21900 gcccaatatc gtccaaagac ggtgttgagg atgccatctc gggcctgaat ccgagaaact 21960 gaagccgcgg tgcgacacat gcctaccatg cgagagtatc gagtctcctg atactgctgg 22020 aggagatgct gaacctggga atttgacggt ttgcaaactc cgcgggcgtt gatgagatca 22080 tgtagaaggg aggagagcgc ggcagcatcc tcgatggcac aattggctcc ctggccaaag 22140 ttgggcgtca tctgattgca gactaagtaa gccgaacgat atcacttcaa ttctcttagc 22200 cacgcacctt gtgaacgcta tcgccgatca acaccatcct ttcatggtgc cacgtctcaa 22260 acaaaccctc ctccagcgct gtcattgagg atacctctct gtttttccac aaatccccca 22320 cacagatgtc tttccagaac cgcacgtgct tgacccgttc gaagagctgt acggcatcct 22380 cgtctgagaa ccgcgggaca tcagggtaga cgtactttct atccaacttc tggatcacga 22440 accagaacac ccgaccatgt ctgccgtgga ttgtcagaat ggatagatgg tcatagatcc 22500 cgttgatctg ttcgcttatc tcgagccctg ggatggccga cgagattccg aaaacgcaga 22560 catattcaac agtcatgcct gcttatgtta gtgttgattg cacccagcac aaagaaggtg 22620 agggacggca gatacttctt ctttcacgcc tcgaaacaga tgcaggccga ttctccccgg 22680 ccattttcca gatctcactt ctcacccgac tatgtacgcc atccgcacca accacgagat 22740 ccacctcata ctctgtccca tcagccacag caacagtaat tccatgctcc aactgtcgca 22800 cttcaactac ccttttacgg gtgagaacgt tatgtttctt tgtcagaccc tcatatgcaa 22860 tttgcaggaa cttctgccgg tccaagaacg caaccggata tccgaaccta taatcttagc 22920 cacagcaccg tctctcttct ttgttcgcat actggtaaac gcagagacta ttgacatacc 22980 tatcgcccaa aaccttcgga tagacgttgc tgaagcagaa cccatctgga tagctaatat 23040 tcgcctgatg caacggctca atcacacgct cgatctcccc aaacaggccc agttgctcga 23100 gaatccgtcc gccatttggc ataataccta tcgaggcacc aacttgcggg gcaatatcgt 23160 ctcctttttc gagtatgagg tactcaatat tggcgcgttc cagacagtgc gcaagggtga 23220 ggcctgcgac agaaccgccc acaataagga cgcgaaattg aggttgctgg gtattggcca 23280 tacttgcgga tgtcgccagt aaccaagcct caatcaaagg taaggctcac ttatggtata 23340 aatatcgtgt tgataccttt acctcaaaag agattgcacc taatgcagaa agattccaaa 23400 ctgcacggta agccaagtgt ttgctattct cactgctgga acgaatgacc ctcaagcgaa 23460 atccagcact gccattgtgg cagaactgcg tagtcaagct acttcggctt atgcaagcca 23520 gtctcgtggt acatgcactt taccaatagt tgctgtgtgt cacaagcgtg gctgttcatc 23580 atgccatcgt ctacttgcaa tcataaatgg cagaaaggta ggtatgcctt gctttattct 23640 acacagctta aaaggacagc cacatgtgtc aagatagcat atacactgct ttatcctgtt 23700 attaaatgct tttcttctgc cggcccaaac ctgtctattg catgacacgc agaaattccg 23760 ttctcgtgac agcactacaa gcagtggtac aacaccgtga actttctccg ccatgccgcc 23820 agaataaata gctgtgtgtt gcacatgcga ctattttcat accgttcctg gctaccaatt 23880 ccggtgatat gacatcttcc cgcagcttat tcctgtctga tgcatctatt acgcacaatc 23940 cctcaacaaa gcatctatct ctccttgtgc ttgattccac gctgggagct cttctcttgt 24000 cgcttgacag aacagaataa cacgccatat aggatctcga agagaaagaa catggccacg 24060 gaccatatca cgagtgggca gtttatatac gaaaaagcct cccaccaacg aaaatatcga 24120 acaagggcaa agccaatggc tgacgttgat ccaaagaacc tcgagatcct agtgaacgtt 24180 caacacaact gattctcaaa ccaggtcaga caaatactta ccatagcgtc cacgatgcgc 24240 ctcgggtgtt tccgcgactc aataattgaa atacattccc tatgctaata aagagctgac 24300 atgcaattgc cccccacgta taggcttgtg caggaccaac ctgggcagta agagccatat 24360 gcccactcag acaacaaagt gttgttgctg cgaagacgag agtcatatgg ttcctcacaa 24420 ttgcagagtg gtgccattca tttggggcat tcttgattcc cgcgtagata actccaaggt 24480 cgagtgaaat gccaacaaga aaggcaaccc gctcgataat gcctttggca ggatacattg 24540 tgcagaaaac aatctcccaa gcaaaattga tgcaaaggcc cccgatggtc atgcagtagg 24600 tacggtcccg gaacgatgtg tgaatcattt ccacatagtg agcaacccag ccgacagcca 24660 ttccaacaac gaaaatattg gcgagccatt taagctcgtt atattcctga ggagcagtag 24720 aatggtcgaa accatccatt aaagcgaaaa taagaggcac ttcaatgctg aatgaatttg 24780 gtcgccgttg agatctgagt cacttgtctc ttgcatgacc tgagcgtgct tatatagtga 24840 gatgacttgc ggtcagctag tgatacggcg ccatggttct gttctgctga cggtacgcca 24900 tgaaggtctg tcagtctcca taagtagact gatgtccgca ccaggtagga ccaccaggag 24960 tctcggtaat tatgtgtcac cagtgcgcta ttctcaagcc cttcaaagcc ctgcaagaca 25020 gccaggggag tgcaccaggc ttcaaaggct gtatctcctg ccgtgccgct aaagcatgtc 25080 gccataccca aatgtcagct tctatcaaga gatagagtca ggcaacaacc gttctggccg 25140 gctcgaccgc acagaagggg agatggtgta acttgtgcga gaaacagctt gtgcagagga 25200 gaaccctgag ccattgacga tgagtgtacg gctgaagtat cctgtctata gcatacatat 25260 atagacagga gaacgtccct ttgcgagccc attggggtac cgcgctgtca tccgttaacc 25320 ttcttatccc tgcatttcgt cccactcagg aaggaccgaa tcatggcggc actgccggac 25380 gttgcctcca ttccccttcc tctggtggca accctgggaa ttgcccctct agttttctat 25440 ctcgtccttg atagatttgg ccctttgtgg ccaaactcca aaactttctt gattggaaag 25500 aagaagccgg agaccgtgac atcctttgag tgcccatatg cctacatccg gcagatctat 25560 gggaagcatc actggaatcc attcgtgcag aagctgtctc caaggcttaa ggatgaggat 25620 ccagccaaat ataagatggt tctagagata atggatgcaa ttcacctgtg tttgatgcta 25680 gttgacgatg tatgtatacc gtgggcctat ataaatacac tctaacatca agcagataac 25740 cgacaatagc gactaccgaa aaggcaagcc agcagctcac cggatatatg gcccttcaga 25800 gacagcaaac cgcgcttact accgagtcac ccaaattctc aatgagactg tgcagcggtt 25860 ccccaagtta gccaagttcc tgctacaaaa tctggaagag atcctcgagg gccaagacct 25920 gtcactgatc tggcgacgag atgggctggg tagcctttcg accgttcccg aggagcgagt 25980 tgcagcctac cgcaaaatgg cgtcattgaa aacaggggcg ctattccggc tgctggggca 26040 attggtgatg gaggaccaat cgatggacgg gacgatgact actcttgcgt atggctcgct 26100 tggtttattg catatcacac caagtctagc tgaagctgaa gctgaccttg agataggtgg 26160 tgctctcagc tgcagaacga ttgcaaaaat gtctactcat ccgaatatgc taaggccaag 26220 ggagcacttg cagaagatct gcgtaatcga gagctctcat atccaatcat tctcgcgctg 26280 gaagcccccg aagggcattg ggtcgccagt gcattggaga ccagctcacc gcgcaatatc 26340 cgcaaggcac ttgccgtgat tcagagcgag agagtgcgca atgcttgttt cagggagctc 26400 aagtcggcga gtgcttcggt ccaggactgg ttggctatct ggggacggaa cgagaagatg 26460 aatctaaaga gccagcagac atagcttttc agtgttttga ggcatacagt ttctcttatg 26520 gtttgagggt tgagaaatca ttcttcttga gatacgttct gggtttaatt tgtgctatac 26580 atatagggtt agatcaaaac agcatatatt aacatttata cgttggagtc cagttcattc 26640 aatgagcaat gaattggtgt gcgatattcc tgtcatcgtc aaaacttaca ttgaccctgg 26700 aataccgtcc agcctgcttc ggatgtagta atgccatata tatagtccga gcaggttgtg 26760 gtagcatcaa gcaagccaca gagggggtac gtgcatgaac catgttacaa ttcggacaac 26820 catcagctgg tgtatccctg cttcgccaac acatctatca gacgtaggat tcaggacagc 26880 ctaggaaatc tgattgatgc tggcgctgcg ctcaccgcag ccactattct ttctactcgc 26940 ttcttcgcga cagtgcttcg tgttcaatgt ctatgtacag ggcctctaag gcggcgttcg 27000 cttcataatc aacctattgt gcacaggctt actgtgctag agctaatcaa cagagcttat 27060 gcatgggctg tcatacctgc cataatgtct ccatacccca tatccacaac caaacaatca 27120 ggggttactt cccttcccta tactattatt gatcccctat acactcccct accaaacaac 27180 ccatcacttt attactttaa gcccccatac catcttatcc caccaaaaac aacacgatga 27240 ccccacccct cctcccaaca tccctcattt cagccatcct cggcatcacc gcccacctaa 27300 catacttcat ccacgccgac ctcgagaagc acgtcgtctt cctggtcaac tgcctcatct 27360 tctggccctc actcggtcta atagccctct ttatcctcgg ctatagagat atttctcaat 27420 ggatcggacc agcaatactg agctttcact tctcgctgtt agcttccata gtcatctacc 27480 gatacttctt ccacgcgctg gacgggtttc caggtccaaa gctggcaagg attacagcgc 27540 tgtgggattt caagaatacg gtgctgaatg cgaaatggta tatcaaggtg aaggaaatgc 27600 atggggtgta tggggatgtt gtccggatca gtattcctcc tctcttccac tcttcccatg 27660 tgatttgtac agggccaatt gattgaatag aacctaggga attatccatc aacgacccat 27720 ctgcgatcaa agatatctac ggcgtgggga ccacatgcgt caagggaccg ttctacgatc 27780 tacattatcc gcatcgatcg ctgcaaatgg cgagagataa ggcgtttcat tcgaagagga 27840 ggagattgtg ggatcggggg tttacgtcga aaggcaggtt tgacatgcat gttctttgaa 27900 tcttatattg actggctgct gtaatgacta gcactcgctg gctacgaacc gtatcttctg 27960 gagcactgca aagatatagt ccgggttatt gaatctcgat catcgcaagc acaggaggcg 28020 acggcactaa ttgatggctt tgcgtgggac tcgatgggga tatttgcgtt tgggaaatcg 28080 ttcaatatgc tgcatgggga accgccaaag atgctgcaga tgatgaggat gatggggcgc 28140 ggggcgagtg ccttattgag ttcgagctgg ctggttatac tcatgagggg gatggtggga 28200 gtgaggcggt ttacggatag atggttagag tggtgtgcgc agtgtgtgga ggagaggagc 28260 agggtatgta tgtttgcagt tactgtctct cttcagttgt ggatggtata ggctgatgtg 28320 tttcaggtcg aaactaatcg ccgggatctc ttcagctact tgatcgaaga gttaagctct 28380 gagggagacc agtccatagg tggcgttgac ggggatcttg ttcgcgattc agagctcgct 28440 attacggctg gcagcgacac cgcagccagt accctcaatg ctctgttcta tctcctggca 28500 cgacatccgg acaagctgcg ccggctgcag gaggagatag acactgctgt tccagctgat 28560 gaggagctgt ctcatgcggc gttggtgaag aagccgtacc tggaggggtg tataaatgag 28620 agtctgcgtc tttgtccggc tgtcttgagt ggattgcagc gtgagacagg accggaaggg 28680 ctccgaacag cgggagtcta tattcctcca gggatgatag tgtctgtgcc gacatatacg 28740 gttcaacgag gtagatcatt aacctttcct gtgaagataa gagctgattt cctttcacga 28800 agacccgcgc aacttccccc gtccaaacga attcatccca gaaaggtggt ccacccagcc 28860 agagctagtc attcataagg aagcactgaa cgcgttctca agcggcacgt actcctgtgc 28920 aggaaaggca tttgcgatga tggagatgcg actgctcgtt tccacgattg taaggcactt 28980 cgacattgag tttccaccag gggaaggaca agaaccgcta gatagattgg gaggaacggg 29040 gccattagac tgtttcacaa cacatattcc aaggtatcat ctactcttca aaaagagata 29100 gatagataga tagattccaa tacagtgtta tgttacccga tattgaatag taggttgtca 29160 tgtagtgacc gtaggcatct accgttactg tttcactcca ttcacaggcc gcatccggcc 29220 aggcaggaaa cacggttaag gcaggggttt caaccaagga actcagctta agcagcacga 29280 attccgtctg acttcaactg ctttgtccct gtctaactgc tactcccttc atggaggttt 29340 cttattatcc ctttacttcc gtctcacttg atcatggcct ccaaagagga agagcgcaca 29400 ggccaacggc ccagcatcag catgtacgat cccgcccgag accgctggga ggagcagcct 29460 gttgttcctg ctgaaccagc gtcagcttct gcttccatcg aagcaacacc aactcagaca 29520 agtgaagcca aaccggtaag ttggtcattt ctctttaaat ttagtccact cgagaactgt 29580 ctccctagtg gagagagcaa gtggagtcct gcagcccatc cactgcgaac taaagtggcg 29640 cttacgctcg gcggaggcgg tgattactat tcttcccgca aataaaagac tccgaaagaa 29700 aatgctcctg cgcgtctgtc tgtctatctg agcgtgatat ttctcagtgt tccatattct 29760 ttccattgca ggatatttga cgctgattgc cgatgtttat tgggtttttc atataggttc 29820 atgattctac tgtgacttct accagtgaat ctcttcatct tcctcaaact accaccatcg 29880 agccttctca acaaccggag cagcagcaga agcagcctcc tatcccgaca cctccatcct 29940 ctcaatcacg ccgcaaacac aaaataaaca aaatgggtga ctactatcgc tctggctctg 30000 cggatgccta cgctgagcag agctctcctg ctgccgatag ccacaagcgc aagctagagg 30060 acgagacatc ggagcagcag ccacccgccg accaagcgaa cgaccgtccc atctccaagc 30120 gtaagcgtct cgaagaacga caccagaagc tgcggaaacg cggccaggca cctccctcgg 30180 cttactcgcg ccgcgatggc gacgagacag cagcacgcgc agcaccacgg ccccgatcac 30240 cctcaccgcc ccttcctccg cggtctccgt cgccggaagt gcaggcgcgt cagcgtaaac 30300 gacccggtgg cggtgcgcgg cgaggtctcg tggacccgca gacactgcgg cggcgacagg 30360 aggagcggga gcgcgcgctg gaagaagatg cgatgcgcaa ctcgcagagc cggggagtga 30420 cggatatcgt gagacagcat tacaatgcgg ttccgcagcg gggccgggag tggcgcaaga 30480 cggagagtaa gatcaagggg ctgcgcagtt tcaacaattg ggtgaagagc acgttgattc 30540 agaagttctc gccggatgag gagttcgtgg cgcgggcgat tgggacgaag gactgggcgg 30600 atggaactgg gccgccgccg atggaggaga aacggttact ggtgattgat ctgggatgtg 30660 gtaagggagg tgatcttggg aagtggcagc ttgcgccgca gccggtggat ctctacgtgg 30720 gactggatcc ggcggaggtg tccattatac aggcgcgcga gcgatatgcg gggatgcgtt 30780 cgggcagggg acctcgtggt ggacggaggg gagggccgcc gttgtttcat ggcgagttcc 30840 ggtccaagga ttgctttggg gagtggttgg gggatgttga tattgttcag caggtgggaa 30900 tagatccgaa tgttggaccg ggagggtcga tgatggcgtc gcgatggggt gggggtgggt 30960 ttgatgtggt gacgtctatg tttgccattc actatgcgtt tgagagtgaa gagaaggctc 31020 gtcagatgct gcgcaatgtg gcggggtgtt tgaagaaggg tggccggttc atcggcgtgt 31080 gtcccaactc ggacattatc agtgcccgcg tggccgagtt caatgcgaag cgcaaggacc 31140 gcgaggcggc gaagcaggat gcagagccag aggacggtga ggtggaggag gaggcgaagg 31200 cagaatgggg gaattcgatc tatcgggtgc gattccctgg agatacgccg gaggatggca 31260 tcttcaggcc gccgtttgga tggaagtata gctacttcat ggaggaagcc gtgggcgaga 31320 tcccggagta cgtggtgccg tgggaggcgt tccgagcgtg agtccattcg atattccatg 31380 gaacattgat tacgatacta atgaagcagg ttgacggagg agtacaatct ggagctgcag 31440 taccgcaagc cgttcatgga ggtgtggcgg gacgaaaagg acgatccgga gctggggccg 31500 ttgagtgagc ggatgggcgt gagagatcgc acgacaggcg agttgacgat gacgccggag 31560 gagcaggagg cagtcagtaa gtatacaccc ttaggtttta cttcagctga aggagagagt 31620 gctaacggga caggtttcta tcatgcattc tgcttctaca aggtgtgaag gataagatac 31680 atagtattag aattagggta aataggattt aatcgacata atcagctcca tatccatact 31740 tgcttcaatc caactatgat acagtataac tatccctata aagtgtagct ggtatcgata 31800 tgatatcgat aagataaact tccccaaaga ccatacttcc caaaacagcc tagcgccgtg 31860 catcgcgtcg cgttcctttc aacttatctt tatccataat cgttatagcc tcaaagaact 31920 accaacaaag aaacctacac catataccat ataccctcct tcttctcctc tatcctcctt 31980 gccacctata tccacaaccc accacccaca ccttacctca attatacact accaccacaa 32040 ccaaataact ctcacccaaa agaaatcaac caaaatgccc aaacgctccc gcccaccacc 32100 accaacagcc acccccggac caagcggaag aaacagaaac agagacagag acaccacccc 32160 ccctcttccc ccctaccaac cccccaccag caccctgacg accctatccc accaaccgac 32220 caccgcaccc gccctctccg ccctcctcgc aacgcacacc tcctccaccc taaaaacgca 32280 cctccagcac gcgcaagaga aactcaccga cgccgcaggc gagatcaacg agcggctcac 32340 agacgcgaaa gagaggagta agaaatcgcg ggagaggagg aggaatatac gttctcatac 32400 tttggagaat aataataata atggtgaggg ggtagatgag gaaggggggg atagtgagga 32460 cgaggggatt gaagagttcg aggagagagt ggctcagacg acgaaggtat tggaggagac 32520 tattcggggg gttattgatg cggaagtgag gggggaggag cttgggaggg ttatctcggg 32580 attggagggc ggggttgctg aacgggtgag ggttaggggt gtgaggagga gtcagagagg 32640 aattgggaga aggttgaggg ggcatcatgg tgaggatgag gaggatgagg atggggagga 32700 aggggtggat gtggatgtcg atgaagatga ggagggcgcg gtgccgttcc tggcgcagtt 32760 cgaggatgag ctgcgcggga agatggagga gtaggaaggg ttgagtttga cgagacggta 32820 tgtatatccc catttctatc ccaataatat tttacttcca ggtttattta ctaacggaat 32880 catggtggta ggtattctac gaacaactcc tacataggtt tctacaaaat catccacgaa 32940 gccaaacaca tcggcgacga aatcccccct ccgcctcatc cgtcgacgtg gttcgctcac 33000 ttggaagatc ctcattctca atctcaacca caatctcatc catctgcctc tacctctact 33060 tcaaccacta ccaccagaca aactagaccc acccgcgctc gacctcaacc cccctccgaa 33120 gaagaagatg aagatgatga tgacgaaatc gccatccaaa ctgaacgcat atcgctgaaa 33180 tgccccctca cactccttcc cttccgcgac cccgtgacca gcacgaaatg cccacacagt 33240 ttcgagcgcg aggcgatatt caccatgatt agcgggagta atcagatggt gcctgatccg 33300 agggggtcat ctggaactgg aagagcgaag cgcgtgcgca gcgtcaagtg tcctgtgtgc 33360 gaggtgcagt tgacggagtt tgatctgcgg agtgatcctg tgctgatgag gcgggtgaag 33420 agggcggaga tggcggagtt gaggaggagg gagagggaga tgttggatga tggggaagat 33480 gatcaggatg gtggtgacgg gggtggtggt ggggggaaga ggaagaggag tgggaggagg 33540 agggggagtg cggttgaggt tgatgatggt gatagtgatg atgatagtgg tgaggatgat 33600 ggggtggaga ggattcgggt taagagggag agagggatgt ctgttgctgc taggattaag 33660 caggagaggg cggtgtcgat ggttggggat ggggatgggg atgtggagga ggttgatatg 33720 gatgaagaag ggggagggga agagggtggg tatgattcta tgtatgatga gtgatttatc 33780 tagctactac aagcattcat gtttctattc tgtagaagca tacagagtag acttatttat 33840 tgcctatctc tatttgaatc tctgctatgt agttgcaata atcacgggta taataaatac 33900 aaacagccat tgaaaccatc aaccatccat cgaaacacca tcctccatcc acaatcatta 33960 gggcatttcg atcttctcct gcatctgttc cagacagtgc aaccagatcc gcacctgtgc 34020 aataatcacc gtcaaacgac agcaaccgcg gcatttggaa aaaaaagttc aagtcaagta 34080 gttgtcgaca agccaacaat atcatgttga atcaatgctg ctacttggta atcaagttca 34140 gataatcggc cacgataagc gtcaccatcc tgtgggtctg gggttagcca agggcactag 34200 tctgatagaa aatggtgggg acactaacgc atgaggagcg atccgcacat agtacgttcc 34260 gaaaccgcgg tagaaccgca accagccctc ctcctggacg accttgcgcg cgcaatccaa 34320 gacgcccttg taggggagcc gaccggtctt cggatccttc tgctgcttct gcaggcgagt 34380 cttgacaaag tcgaaaggca gggagaggaa actggcaaag aatcccgcga tagcggacgc 34440 ggcaaaggtc tggttctgag tcgacaggct agtgtgcttc ttcagctgcg ccttggactc 34500 ggcaaagaag gtcaactggc cgacgttgag cgccatggca cggatgacgg tagggaaagc 34560 accagcccac agagccggga caccttcgtg cttggagatg cggaagagcg cgtccatgac 34620 ggagcggtag ttggcccgcg cctcgggagg tttgagaccg tctgactgca tacgcaccag 34680 tgccagatcg gccgggttgc caatcatggc ggcaatacct ccggcagcta gaccggcacc 34740 ggcacgttcg gcgaaggtga cgctgcggtt ggcggcttcg gcacgcttgt tgagagtctt 34800 gctgaaggtg tcgaagaaac ccaggcgggc ggtagtgtaa acggcctggc gcagcagtcc 34860 agccgacaga ccggtgtaca gatcaagtgc tttgcctgag gcaatgatgt cgcgggccac 34920 gccaaaggca gacgggcggg gaccggtgcg cacaccttca ccggcgagct gcaaacggac 34980 tttgatcatg tcgatgggct ggatcacgac cgtggcggtc atgccggcca ggccaccatt 35040 cacgaaggga agagcagcac gggtgtaagg gtgatggagg aaatcgacgg cgggctgggg 35100 ctctttggcc gcggtggggg aggccatgtt gacgaggaag caggattcac accagatcta 35160 gagggtgaac gagggttaat gcgaacactt tggaaggtga ggcggatgag acgcgccgaa 35220 cgaaggattc aagaggagga atacagatga acgaaggatg aaacgcgaaa taaaagacaa 35280 cacgatacac ggtgtggggg gtagtggaga gacgaccatc tagccatgaa aagaatcgag 35340 tgcctggctc agcaaagaga ggacagattt tctttgccag gcactttcag catgaccgac 35400 cgtgacgtga ggaaacgcgg gaggggagat tcaacgtacc gtggatgcac agctgggcga 35460 agaggggaac ccggtagagt cacgaaaagg cccgacgaga atcagtagga agtggtgaac 35520 cgggttttgt tgaggaggag aagttgggac agtcagatga tgggggaagc ggaggtgcaa 35580 ggcgacgaag aagtgaggag gcgagagttg gcagtgagtg aatggattaa tttgcaaggt 35640 tgtacaactg gaggcaagtg tctgggtggg tgattctgat acttataacc tgtgcatgag 35700 ttgcatgagt caaggtagca ttcacgggga ttcgatgatg tatttgtatg ccttcgattc 35760 catccgagaa gccgaccagg gaaacaagca gtatctactt gattgactga cagtcgaaat 35820 ctctccagac tgggtaacta tttccatccc cacttttgtt agccgatgcc aaacttaagg 35880 cccgagcgat cgatgaggat ttagtagtat ttggtagtat acccagtcag taagtacttg 35940 ctgcacgatg ccgccagctg gaaaatgcgg ggttgccacg tctgatgtcc tttttttaat 36000 catgttattt gtgtcttcga tgaagttgtt ctcttctcta ttgatgttgt aactctactt 36060 cttcttccaa taacagtaat attctttgaa aactatcagt gtattgcaaa tatccagaaa 36120 tccatacaaa cagctactaa taccaaaacg tcatggcggg gaataatcgt ccatcataca 36180 taattaccgt atctccccac acccccgcta aaccccatcg ggactaacca cgagaacggt 36240 ccggtttgcg ctgcttcttg ccgccttccc gaggttatct ctcctccttc cccagtcttg 36300 actagcgatt agtcataaat gctgtgaatg ggaaatattc ccaaagcttg gtctcgccga 36360 tcagtctaag gtaggtactg tctgtccctt cggagatatc tggtcatata acatattctt 36420 ttttcgacgt caacaccggt ataccagcta ctatgtagta gcactgcctg ctagaaacaa 36480 gacagtagac acatgatatc acaatatcat ctacaaataa caatcatgca tccccggaat 36540 aatcatctcc agatcccatc ctaaatgctg cattatctcc tttccaccga ttcctccgac 36600 tttcggccct tctccccctt tgtgtctgcc actgtcggcc ggagaagatc tcctccgtcc 36660 tcacttcagt gacaaagtga tgactactca gtggcgtagc aactatctct gatcgaatag 36720 caggatgcca gtcaagtagc cgggaacgtg gatgactcgg ttggcggtaa cttgttggct 36780 atatcccgga gcactgatct cctagtctcg tactcctatg ttgggaatct acatctacct 36840 acaacaacag acccatcaaa gctagtagac aatacacgcg gtatcgtaat tacaattcca 36900 aaaagggtcc tctcgatccc caactattcc aataagacac cccttttctc catactgagt 36960 actagatagt ggatggactg gggcgacgga taccttcgcg gcaaccgctc ccccctggcg 37020 gcagcacgtc tcgggatccc ggagcgggcg aggcgggtat cggtagtcgc gcgcggtgag 37080 attcatctct aaccctcggg tactctcccg ggacaggatc cagcaaggag taatcatcag 37140 cttcctgact ggctggttac cctgtcagga ggtccaggcc cccagccgga ttagctactg 37200 gggcttagac tacgatcctg tctgtgggga ctacctgcca caagcgagct gcaaagaaaa 37260 cagccgattc tcgctggaat gcccgtctca tatcggaaca attgtcatct gcatgctatc 37320 acctactgat ctggcggcct atattgctcc ttgtatccgg cggaatagcc gacttggttt 37380 gtcctttgct ctgtctgccc gcgcggccca aatgaaggat cgtccctcgt ttctggctga 37440 tgatgtgctc gtagagttca aattcctgcg aatttgttcg cccaatgccc gctcccgcgt 37500 gtctgttcgg cggccgtggc tggccgtcaa gagtcgtagc tccacatgat gctcaccagc 37560 gccagctaga gctctagctg cgctagatgt cgcctgatgc acgcgcgcgt gcgttgcgag 37620 atcgtggatg ccaccgagat aacgccgagt ttttctgtcc ttgactctgc tccgttgaac 37680 agccatctct tgggaagata ttcgtccagg cgagggaaat acaacgggtt gtggtggatg 37740 ctataaatgc ttgtaccgac gcaacacccg actggaatca tggccgtcca ctatgattgt 37800 gtcgcctttc tcgaccggac ggtacgggca tcttgccacg gccggcgagt tgcgtagggt 37860 ctccttgatg caggcttgga agtatgtgca tcgctgcatc gattggctgc tgcggatgtc 37920 atccggcgtg ggaaacacgc tccatatttt gtgcgccagt ttctcgtatg cggtgcttag 37980 attgccaggt agagattcgc gcacagactg acgggagtga aatacgaacc tgggtatatt 38040 agtgttgatc atctaccgaa gcgggagacc taccaacagc cagcattact gattcaaaat 38100 atacatctgc atcagtcaat cctgggcctg tggcactgtc gtgggccttg gtcaaccaac 38160 tgaagacgtg tccggacata ctcgccgcgt ccgccatcat gccattgacc agccgatgat 38220 atcgcttcat ccctcgaaca tccttgaaca acttctcgcc cagccgaccg agaaacgcct 38280 acagcgcata cattagcagc aataatcgct tcatcatccc caaggcaccg tacaccgtac 38340 attggaaatg ctggctgcca agcagattac cggccttgcc gaatataaga tcggtgatca 38400 cgtcgaaggc aaagtagctg cactattccg acatggtcat gggtacaatt gcgcgagata 38460 gagggaatcg cggaacttgg gaacatgcga cagatgattc ggttcgcatt cccacatagt 38520 ggtacttgag aaaccaggtc cgatggtttt agtccgtttg gcatgttctt ttggactcgt 38580 cacggttagg agattcttcg ttcccacttg gattgcggat gtcagctaca ttttcatcag 38640 gatcaaaatg agcaaacagt aataaactta cactggcaat aataacgcca gctcccactg 38700 ggatttgaga gaggatggag agaggaaaag aggctgtcta tgatgttgtt gtcttcaagc 38760 ctttctcatg gcgacagcat agatgcacta tgacagatat ctttcactga aactctcacc 38820 aagcagagcc cgtggttcgc ttgtatgcgg atcctctggg tttgccattg tgagagggga 38880 actttcatca gtagttctaa tggcaaggca cgtcgcatgt cataaagtat aggaaaagca 38940 aatttaggcc acacattgga gagtctctcc ttggaaatta aagtgcgtcc gttgatgcaa 39000 gtctacaaag ttcaacgcgt cagcgtgcag ctagcagctc tgattcgtgc aaccgaatag 39060 ggtgaagggt gggcagtgaa taattcgcat ttccatgaga ctgttggact tcctgacaca 39120 agatcggcca ttatcatgat aattggtaga gaggtgcgtg aaccatgtcg cgaagtgggt 39180 gacagacccg gagttggacc ggaacctgga ctgtctttct gctggtggtg tcagaaggta 39240 gattgctgat gctttgactc tagatcgtct cgaaacatag attagaagta taaatcacaa 39300 aaggtttacg gtcggggcat cacagcaatc agttgcagat agcatacgga tggatggcag 39360 gcagcgttgc ggaaaagcaa cgagcgagtt gcagacgcta aacggcgatc acatgtggag 39420 caaggatcga ccccctgttc atccccgtga cccgctgtgg attcaaggaa ggcttgctac 39480 ggtggttgct aggatagatt gaatacttct agatgatata aaggtataat tttgaattca 39540 atttctaatc gttacctcga cttctaaaga agccaaaacc caaaaggaaa tgccaatggt 39600 attttccccg ccggccgggg taggccacac atggtagtgg aagattcaaa tgacccatga 39660 ttggaaacgc aacacgccat gcaagatatc aaaagcagat aaaaggaaat gtaaaatcag 39720 aatgcgaaac aatttactga ggcaccggac cggccgcaat gacctcgggg gtcgcttggt 39780 cagcgtactt gccgaagttg tcgttgaaca gcttggcaag cttgttgacc tcgtccgaga 39840 agttcgtcga ggcggtccag ctgttcttgg ggttgaggag ctcggaagga acaccggggc 39900 agctcttggg aacgtgcagg ttgaacacat cgtaggtctc gtactcgacc tcgttgaggg 39960 agccgttgtg gatggcgtcc aggatggcac gggtgtactt gagagggcaa cgcttaccac 40020 cggtggtagc gccagcacca acccaaccgg tgttgagcaa ccaggcgttg gccttgtgct 40080 gcgagatctt gtccgccaac atgcgggcgt agcgcatggg gtgcagggcc aggaagggct 40140 gggcgaagca ggaggagaag gtagcctggg gctcggtgac accgtcctca gtaccagcca 40200 tcttggaggt gtaacccgag atgaagtgga acatggtctg ctcggtggtg agcttggaga 40260 tcggggggag gacaccacgg gcatcgcagg tgaggaggat gatgttcgag gggtgcttgt 40320 cggacaagca ggggatcttg gcgttctcaa tgtactcgat ggggtaggca cagcgggtgt 40380 tctcagtaag ggtggagtcg tcgtagttga caacacggga gatggggtca aagacaacgt 40440 tctcgaggac ggatccgaag cggatggcgt tgaaaatatc gggctccttc tcagcggaga 40500 ggccaatgca cttggcgtag cagccaccct cgatgttgaa gacaccacgg tcggtccagc 40560 agtgctcatc gtcaccgatc agggcacggt tggggtcggc agacagagtg gtcttgccag 40620 tacccgaaag accgaagaag acggtcacgt cgccgtcctt gccctcgttg gccgaggagt 40680 ggagggtcag aacgttgtgc ttgacgggca tctcgtagaa gaggacagtg aagacaccct 40740 tcttcatctc accagcgtac tcggtaccca ggatgaccat ctccttctcg gcgaagttga 40800 tggcgacgga ggtggcggag gtcataccct cagtgaagcg gttggcgggg aaagaaccag 40860 cgttgtagat aacgtagtcg gggtggaagt gcttcagctc ctcctgggag gggcggataa 40920 gcatgttgcg catgaagaga gcatggtagg cacgggcgca gacgacacgg acgctgatgc 40980 ggtatctctc gtcccagccg gcgaaaccat cgataacgta gatgcggtta cgggtgttga 41040 ggtagtcgac agcacgctca cggttgatgc gccagacctg caagtcggga tgccgttagc 41100 aaagaaattc ggatcatgta tgacgtcatc tggacgaccc cgacaaggcg caagttggcg 41160 aaacaagcat tctcaggaac acagccggac agaacccaaa cttttgtgtc gcacagcagt 41220 cgcaagacag aaaatgcctt aaaaagtcta taatgaggca tttctttctc cccgatgtgc 41280 tgccagaaaa gcttgggtcc atgccagctg caggcccatg caagggatga tctttatgcg 41340 cgatatattg cacttgcagg ggaaccccaa aaaaagacag caacgaaggg gaaacacgta 41400 catcaggagt catgggcttg ttgacaggtc cccaccagac atcgttctcg gaggtctcct 41460 ccttgacgat acgcttatcg gaaggagagc gaccagtctt agctccagag taggcagtca 41520 gggcaccgct ggaggtgata gcagtaccag tctcgtagac cagagcatct tcgtagagag 41580 cagggacagc agggttggca atctatcttg attagcaagg ctcaaaaaca ttgcgacggg 41640 taagcttaca atagcgacgc ggtcatagtc aatgtgggcg tgttcgtgaa gctcttcctc 41700 gagctcagtg tgacccttgc ctggcctgga gggtcatggt tagcaatgat ctataccagg 41760 caaggtcata gaatgatatg cgacgcattg cgcaggccgt tgagggtaac cccgagcaat 41820 gcgacaaaca tatcaagaaa ggaacgggta gatagaagag agggacaaga catactgaac 41880 accaccaggg tgcagagcag tgcgattcac cgaagcagca accatgtttc ttagtgaggt 41940 agaatgatag ttattatttc tttgttttgc gagttgctgt tggaagaaat ctgaagcgag 42000 aggaccaggt tcagcggggg aaacgggggg tatatgaatg tttgtcgcag gactcataat 42060 gggcgatcga agacgcctga acgtgtggaa ttgcagctgg aaatgtttac tccaccgttc 42120 cacggaagat gtcggggcag cagaccgaat ctggacgacg atggttatcg tgaagagtgg 42180 aaaaggaaga caaatgcctc gaattgaagc ccgaaaagtc ccgaacccca gatgtgggca 42240 cgaggtggtc ccggaaggga tggcggatgc accaactaga agtgagcaaa taacacaagc 42300 ttcggaaaca ggatcagaga tttgaggcgg tatcacggat agcgcgtcag gggatgatga 42360 attaatgtct cattaacggc actagtggga gttggtacgc aggtttggag tgctttggag 42420 tacagggatg ggacgcttaa gctgctagtg agggccagag tgggaattcg tggccccagc 42480 gctacgggaa cgaggtattt atcattatgt gatggtcttg cagcctgccg cgcgcagcca 42540 ccaccggatc atcgagtgaa tgaatgctga aaagaggtca ttcaattaca atttactgag 42600 ttccaaggac aaaaggaccg tctactcctg ttagctggcg gaacaaataa caatggacgt 42660 agagagacgg gcagatggaa cgggttggag tggtgacgtt gaatgagctc aatgtaagag 42720 acggagtcta gaggcgataa aacaaaccat agctgcgtac tagggaaatt gcggggggaa 42780 ggaagatttc tttttctttt tttttttttc tctttttcgg ctaggagggc tggactatac 42840 ccgaccaggc gactcgtgtg taatgcattg ccaggactgg ctgagaactg gcacaaaatg 42900 gagacagagt tagtactgct ttcaagtctg ggcccgacca gaaacgcaga agcagcgatt 42960 gcgaatggaa tccttccgag tgacgaaatg ccgggggaga atctcgggtt cccctcgtcc 43020 gcactttccc gcttccggta tcatcttagt catccccttc ccgaaacgtt cctgcccgcc 43080 accaatcagc atccggatgc gcgaccgatg gacgatccaa cgtcactatc atgggcagaa 43140 gatattgccg tcttttcggg ctcgagcact attttcgggt gcgctgtaat ttgaggcaaa 43200 tgagagctat cagctggatc cgagtcacat ttctgggatt ccatgtcata ccgatgcgtg 43260 cttttgccat tgtcaacccg ctacgtggac ccttgaagga tggtccccct tactgcagta 43320 atatccctca tacatgagtc tcagttctta tctactgact gtaggttaca aatatgagat 43380 gcatggatgc cgaaattctt attctctcag tatgagtaga taaaaaagaa gggggggggg 43440 cttcctaaca accacgataa ttgcacatga tagatcaact tcgccccctt tccgagttcc 43500 caagaatatc cgagttgccg cccccggctt tggtcaggtg cctggaacac cccccatttt 43560 tgcctcccac gcggacaatc aaagaaatgg cgtatgacgc attggccaag agaacgtagg 43620 ccgggatgtt atcacggtag atacatgcga cggagaatta gtgccctggc attggattca 43680 gccaagatgt cactgcggtg tctttcccct atcgagccac agcagcaatc tgtaccccgc 43740 atccgaggag tgccggggcc acgcgggcct ttccccggat gttctcgtcc cttgggggta 43800 atccgattcc ggctagagcg tagattaaac gcttttccgg ttggtggatt cggtagtcta 43860 ctggttggcg agaggtctgt ttgaatattg ctggtgataa agggtctata cgagtgtttc 43920 tgatcattgt agccttccat tgcacacaag tcacctgtcc tagtctgtgc ttatgtgtta 43980 tctatcattt ggttttcgtg tcggatacga actacagttt cggctcctct aacaggctgt 44040 taggctgtta gcttccgtgc ctaattcgat acatctgcct tcaccgactt ctgcgccacc 44100 acttcataca ttgagaccct gcaatgcact tatccgcaat caatttgtgt tatttgggaa 44160 tagctactat aaacggggaa ataaggccgc aatacgtgta gtttagccag taacttgggt 44220 atcaagttca tctgtatcac tcagtaatga tattatatat tttcctccgc actacgctcc 44280 tgtggtcgta aatactacga cattggacct catacagtag tactgttgat tgcagacaac 44340 agaaacacga gtggatcttc tagtgactta aatttccatt ttctaattac agcataaagt 44400 acaattattg aaaagctagc ggcaatagta tactggagga tgcacgacct ggcgaatgaa 44460 aacaatcctc tccggttgtc cctgtgcaca tgacacattt ccatattcga catagtgata 44520 tatatggaaa gaatcgtcga gttcatgaag gattcgatgc tatttagtac taacgctgga 44580 gcgagctagc cagtgcagta gctccaatcg ctcatctaga ccggccggca tgattttgtc 44640 ttttcctgat caaggcatct gcctaatgta tgtgcgcgtg atgggggttt ctcagctcca 44700 gttcattgtg tacctggcca ggctagtgtg gatacctgca gactgcacgg acaggtagcc 44760 cctgtgtgca tgccgcatag ggtacgataa tcggagaagc tcgctgtcct ttgatgaaag 44820 actgataacc tacacgagta agttgtgtct gtcagatgcg ttggactgtt cgatctacta 44880 tctactttgt ttctaatcgt ggttccgacc acacattctt atctcgcaag aagactttca 44940 acggaatcac tcgaagcttt tgaaccagcg catcaagtac gttctgctgc tcccaatgat 45000 gtagactggc tgtaatacct caaagtctgc taccaggcag aacatcggaa tatcattcga 45060 tttcttcggc aagtgttata gtatctgcca aaaagtccag aatacatatc gttggcgact 45120 cagtgcgatt aacggtatat cttaggacag aagaggctta atttatatag ctggtccgag 45180 aatggaaaag actgatccag caaggctacc gctatccgcc aatatcatcc aacctcccga 45240 gtcgtcggta tctgagacgc gttttaaaaa agcccaataa ctgcaaatta ctcactaagt 45300 tggtcactgt gtcgcatctt cagccctgga ccatcgcaga ttatcctcct tatcatttgc 45360 gtatagcaca cggtaggcaa gttttctgat tcccatcaac aagattgaga ccacccgtcc 45420 gaattttcac tcctgggtca atgagctgcc tttttctgcg aaaaatcaaa tacacctcac 45480 tttgcacatt ccaagcgccg atattggcta tcactgatac tcaaacccgc gtctcagcct 45540 cgattccaac cttgagtccg cccctaccat gccgtgtaac cggtcgtccg gtctatatat 45600 gaatctcaac gactgtttca cctcactaac gaccagtatc atgcatctga ggcattgagt 45660 gtctatatca aggtaggcat tactacatac tgtccggatt cgcctcagta actaatgaga 45720 taggcgcata aggctctctg atgtcagcta gccatggcgc atcatgacaa tttcgcctgg 45780 aatagctttt ttttttggcg tcaacggtga tgcctcgaag ataccctcaa gaggatgtgc 45840 aaggtctcga accagcggta taagaagacc ttggatgccc gccgcaacaa gatcatccca 45900 agaataatac agctatgtat tctcaccctc ttcaccaccg tcatcctccc ccaagcagcc 45960 gagcctggaa atttgacccc gagcgagacc aatgccatag tctctcgcga ccgcatcacg 46020 gacgtcgacg acaactggat tgactgtgac atctcctggt aaggaaagac ccattctttt 46080 ctgtcccaag caacaaccca gacctgtaca agacctgcac accatattta ggcctgtctt 46140 cctgacatga cctgatctaa cgcgctacgc tgaaatgaaa ggaacgccct cgacatggtg 46200 cccagatctc gggttatcaa ctgcaataat ggtcaacaca ggttaggaat aagaagcatc 46260 cccaatgaca ttgcatacaa ccctcgaacc atgtaacatg cgtcgatcac taaacaaccc 46320 ccactcacat catgcacatg aacattccca agaaaacatc aatcag 46366 // |
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