 |
|
EBI DbfetchID AL939131; SV 1; linear; genomic DNA; STD; PRO; 303550 BP. XX AC AL939131; AL049863; AL158057; AL158060-AL158061; AL355753; AL356592; AC AL356932; AL357613; AL590435; AL592126; AL596248; XX DT 25-OCT-2002 (Rel. 73, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 4) XX DE Streptomyces coelicolor A3(2) complete genome; segment 28/29 XX KW . XX OS Streptomyces coelicolor OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Streptomycineae; Streptomycetaceae; Streptomyces. XX RN [1] RP 1-303550 RA Bentley S.D.; RT ; RL Submitted (09-MAY-2002) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Streptomyces sequencing team, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL sdb@sanger.ac.uk XX RN [2] RX DOI; 10.1038/417141a RX PUBMED; 12000953. RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L., RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H., RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E., RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D., RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.; RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor RT A3(2)"; RL Nature 417(6885):141-147(2002). XX DR EMBL-CON; AL645882. XX FH Key Location/Qualifiers FH FT source 1..303550 FT /organism="Streptomyces coelicolor" FT /strain="A3(2)" FT /mol_type="genomic DNA" FT /db_xref="taxon:1902" FT CDS 135..1643 FT /transl_table=11 FT /gene="SCO7252" FT /gene_synonym="SC5H1.40c" FT /product="putative regulatory protein" FT /note="SC5H1.40c, possible regulatory protein, len: 502 aa; FT similar to e.g. SW:SP15_STRGR (EMBL:M32687) Streptomyces FT griseus sporulation protein (529 aa), fasta scores; opt: FT 394 z-score: 452.2 E(): 7.2e-18, 27.9% identity in 530 aa. FT Similar to SC7A1.26 (EMBL:AL034447) S.coelicolor possible FT transcriptional regulator (500 aa) (43.0% identity in 491 FT aa overlap)" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q9X7U7" FT /protein_id="CAB42965.1" FT /translation="MSKEPNTRLSDLFGLAGWSKGELARLVNRQAAAMGHPQLATDTSR FT VRRWIDMGEIPRDPVPRVLAALFTERLGRVVTIEDLGLVRHGRAGKRPHDGSEEHPDGV FT PWAPERTAAVLTEFTGMDLMLNRRGLVGAGAALAAGSALSSAMHDWLHTDPALAADAPD FT LHQPLHADPAGFDRYEAAPIGSQEVEELERSVEVFRAWDAARGGGLQRKAVVGQLNEVG FT GMLAYHHPPHLQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFVIAAHAAREGGDRPRA FT GEALSRAARQMVHLGKPDEALDLMKLAQSGSGEQVLPRTKAMLYTIEAWAQASMGKGQA FT MRRTLGRAEDLFVSDKADVPPPDWMQTFKEEDLYGMQALAYRTLAEFEPGAAAHAQHYA FT DKALALRIDGRQRSKIFDYLSMASACFIADDPEQADRYARLALVSMGSNSSQRTWDRLR FT QMYRLTAEYAGYPKIQELREEIKLALPKGKSPRGKGPGGTVAPA" FT CDS complement(1663..2979) FT /transl_table=11 FT /gene="SCO7253" FT /gene_synonym="SC5H1.39" FT /product="hypothetical protein" FT /note="SC5H1.39, hypothetical protein, len: 438 aa; unknown FT function, probable CDS suggested by positional base FT preference, GC frame analysis and amino acid composition" FT /db_xref="GOA:Q9X7U6" FT /db_xref="InterPro:IPR010822" FT /db_xref="UniProtKB/TrEMBL:Q9X7U6" FT /protein_id="CAB42964.1" FT /translation="MSSHLSADHPAAQSPGQGSVEALISQTRRLRGDVDAVRRDSQDDT FT TDPRGRWQRALYDLALHQLTDLDAHLAQLRDGPAPAPRAGSLLSRVGSAEWNLLTDEAE FT WSAELFHILGRDPASVPLSLDELPSLVLTEDRPKLTAMVTDCLVDGRPIDGEFRVVRPD FT GSVRTVHMMGEPVLDADGSTASMWAVLRDVGELRRSQRAVSETRDSLRRRPASPWHGLL FT RFPDEGRPGLDLAGAHLPPTSATGRRSREGGWYDACPLGADGETLITVGDFGLPEADAY FT GPAVLIGALRGLALAGTRPGRLRDRLAELLRATALAPVDGAVYCGYRPDTHTLTWAHAS FT GPAPLLFRGGTGHALSGPDGPAGQDGPSGEAEATLEAGDLLLLHTGALEPEAVEHLLTL FT APRLTAADSAGDGVRLVTRELDGFPGRQDACVLIARVTP" FT CDS complement(3252..4280) FT /transl_table=11 FT /gene="SCO7254" FT /gene_synonym="SC5H1.38" FT /product="putative myo-inositol dehydrogenase" FT /note="SC5H1.38, probable myo-inositol dehydrogenase, len: FT 342 aa; similar to many e.g. SW:MI2D_BACSU (EMBL:M76431), FT idh, Bacillus subtilis myo-inositol 2-dehydrogenase (344 FT aa), fasta scores; opt: 864 z-score: 958.5 E(): 0, 38.1% FT identity in 336 aa overlap. Also similar to SW:STRI_STRGR FT (EMBL:Y00459), strI, Streptomyces griseus streptomycin FT biosynthesis myo-inositol oxidoreductase (348 aa) (32.7% FT identity in 343 aa overlap). Weakly similar to TR:O69945 FT (EMBL:AL023862) S.coelicolor possible oxidoreductase (430 FT aa) (29.8% identity in 228 aa overlap). Contains Pfam match FT to entry PF01408 GFO_IDH_MocA, Oxidoreductase family, score FT 153.50, E-value 3.6e-42" FT /db_xref="GOA:Q9X7U5" FT /db_xref="InterPro:IPR004104" FT /db_xref="UniProtKB/Swiss-Prot:Q9X7U5" FT /protein_id="CAB42963.1" FT /translation="MSELLGVAVLGAGHMGADHIRRVDQVVSGARVAAVADPDAERAKE FT AVGGIGGTGRITVHTDVEAALDAPGVEAVLIASPGEAHEEALLAAFARGLPVLCEKPMA FT PNSAGALRVVEAEARLGRRLAQIGFMRRYDAEYRQLKSLLDGGRLGRPLMLHCVHRNVS FT SPPHFTSAMLINSSVSHEIDAARWLLGQELSAVTVLRPRPSAGAPEGLLDPQLVLFETE FT GGAVVDVEVFVNCGFGYEVRCEAVCEAGSARIGAAHTMMVTAAGGAREEVPQDYLVRFA FT DAYDREVQSWVDATRRGLVTGPGTWDGYAAAAVAEAGVRALDTGVRTPVDMAPRPSLHD FT RA" FT misc_feature complement(3549..4268) FT /note="Pfam match to entry PF01408 GFO_IDH_MocA, FT Oxidoreductase family, score 153.50, E-value 3.6e-42" FT RBS complement(4291..4295) FT /note="possible RBS" FT CDS complement(4404..5498) FT /transl_table=11 FT /gene="SCO7255" FT /gene_synonym="SC5H1.37" FT /product="conserved hypothetical protein" FT /note="SC5H1.37, hypothetical protein, len: 364 aa; unknown FT function, similar to TR:P73120 (EMBL:D90903) Synechocystis FT sp. hypothetical protein (358 aa), fasta scores; opt: 492 FT z-score: 559.6 E(): 7.6e-24, 31.6% identity in 364 aa FT overlap" FT /db_xref="UniProtKB/TrEMBL:Q9X7U4" FT /protein_id="CAB42962.1" FT /translation="MEHDLSPATLAGLRRPRPYPAVSVLTPTHRREPDNAQDRVRLRNA FT VAAAKKQLEEDPAVSRDRRAEVSLELDRALAEIDLTYAEDGLAIFAAPGEHQVWTLSRS FT VPERVVLSDTFLTRNLVAAQAAERPFWVLSVAADRVKLWSGGAGRVVEEHLGGFPLDRP FT AEDFDPERQERIGDAPSTFRDEGTRRFLRDTDAAMGRILRAHPRPLYVTGPEPALSLFE FT EAGALASDAVLVPHGGLAHGTAEAVWQAVRPVLEKEARGSVEAVARELDAARGRKDFAA FT GVDELWESAHTGRVRLLAVEENFKVTMRDDGEHLLPADDGDLDAREDIVDEIVEQCLET FT GADVRFVPDGALGDVDGIAGVLRY" FT RBS complement(5513..5516) FT /note="possible RBS" FT CDS complement(5580..7211) FT /transl_table=11 FT /gene="SCO7256" FT /gene_synonym="SC5H1.36" FT /product="putative protease (putative secreted protein)" FT /note="SC5H1.36, probable protease (putative secreted FT protein), len: 543 aa; similar to many e.g. TR:Q54398 FT (EMBL:L42758), SlpD, Streptomyces lividans protease, (539 FT aa), fasta scores; opt: 697 z-score: 769.7 E(): 0,35.8% FT identity in 545 aa overlap. Similar to other S.coelicolor FT proteases e.g. SlpD, SCH5.02c (EMBL:AL03563) proteinase FT (539 aa) (35.8% identity in 545 aa overlap). Contains FT possible N-terminal signal sequence. Contains Pfam match to FT entry PF00561 abhydrolase, alpha/beta hydrolase fold, score FT 55.00, E-value 1.6e-12" FT /db_xref="GOA:Q9X7U3" FT /db_xref="InterPro:IPR013595" FT /db_xref="UniProtKB/TrEMBL:Q9X7U3" FT /protein_id="CAB42961.1" FT /translation="MQAKLETRPSVRRCAVTGALGLALLGAGLPAAASGATTATTRDTG FT SGLSRFYDQRVEWTACEGTEMPKDLQCGKVTVPLDYSRPRGGTLDVALARYRATGDSRG FT SVLLNFGGPGGSGINELALGGKEFMHLTNGYDVVTFDPRGVGRSSPVSCGPATLKIMEA FT TDGDGGMTDPEGVLERLRDAAAECAKYSGPVLPHIGTVDAARDMDVMRRALGDDRLNYL FT GFSYGTRLGAVYAARFPDKVGRMVLDGVDTLTEPLAEQGLAGARGQQTALENFLDWCVE FT DVACPFGQDARDARDQVERLVASLDSDPVPSAFGEPFTGQDMVGAIGQALYSRELWPSL FT ERALAQLLEDGDTRGLEGFSSGGVTFPVRAAVNAPVRGDRTAGLTDEEDVPMDNLPAAL FT MAINCADDPDRPTAAQVTASLDRLRARYEDVSPVFGRYRLTQVLMCYGRPRGTDYIRDD FT VKDLDTARMLLVGTRGDPATPYRWTTETADRLGPSAVVLDNRGEGHTGYASSKCVHRKV FT DDFLLYGSLPPDGSSCGPESTGDGSG" FT misc_feature complement(5910..6809) FT /note="Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold, score 55.00, E-value 1.6e-12" FT RBS complement(7217..7220) FT /note="possible RBS" FT RBS 7437..7440 FT /note="possible RBS" FT CDS 7445..8158 FT /transl_table=11 FT /gene="SCO7257" FT /gene_synonym="SC5H1.35c" FT /product="putative secreted protein" FT /note="SC5H1.35c, possible secreted protein, len: 237 aa; FT unknown function, probable CDS suggested by positional base FT preference, GC frame analysis, amino acid composition and FT the presence of a possible RBS. Similar to TR:Q9AD93 FT (EMBL:AL590507) Streptomyces coelicolor putative secreted FT protein SCI52.16c, 259 aa; fasta scores: opt: 566 Z-score: FT 492.9 E(): 8e-20; 46.154% identity in 260 aa overlap. FT Contains possible N-terminal peptide signal sequence" FT /db_xref="InterPro:IPR019931" FT /db_xref="UniProtKB/TrEMBL:Q9X7U2" FT /protein_id="CAB42960.1" FT /translation="MRRVTRNGVLAVAASGALAVTMPAYAAFASDGAGAEGSAAGSPGL FT ISGNTVQLPVDVPVDVCGNTVNVVGLLNPAAGNGCADSGEPGASYQAAGASGGTSGSAT FT EATSGGAAAEGSGKDSPGVLSGNGVQLPVHLPVNVSGNSVNVVGIGNPAVGNESTNDSG FT DHPEPVRPPAEPEPSAPEEERAGPGPSAHAAPPREEVSLAHTGTDRTLPTLAGGAALVL FT GGTVLYRRFRPGSGD" FT CDS complement(8206..8691) FT /transl_table=11 FT /gene="SCO7258" FT /gene_synonym="SC5H1.34" FT /product="hypothetical protein" FT /note="SC5H1.34, conserved hypothetical protein, len: 161 FT aa; unknown function, similar to hypothetical proteins e.g. FT TR:O59834 (EMBL:AL023590) Schizosaccaromyces pombe FT hypothetical protein (162 aa), fasta scores; opt: 224 FT z-score: 282.3 E(): 2.1e-08, 28.6% identity in 161 aa FT overlap and weakly similar to SW:FCA1_CANAL (EMBL:U55194), FT fca1, Candida albicans cytosine deaminase (150 aa) (30.1% FT identity in 93 aa overlap)" FT /db_xref="GOA:Q9X7U1" FT /db_xref="InterPro:IPR002125" FT /db_xref="UniProtKB/TrEMBL:Q9X7U1" FT /protein_id="CAB42959.1" FT /translation="MVVKDTELPHLRRCVELAAQALEAGDEPFGSVLVGADGSVLAEDH FT NRVASGDRTRHPEFELARWSAARLTPDERAAATVYTSGEHCPMCAAAHAWVGLGRIVYV FT ASSEQLAGWLEELGVPAAPVRPLPVREVAPGVTVEGPVPQLTREIHALHRRFYAGRA" FT CDS 8834..9793 FT /transl_table=11 FT /gene="SCO7259" FT /gene_synonym="SC5H1.33c" FT /product="conserved hypothetical protein" FT /note="SC5H1.33c, hypothetical protein, len: 319 aa; FT unknown function, similar to TR:O33938 (EMBL:Y11199) FT eryBIV, Saccharopolyspora erythraea putative deoxyhexose FT reductase involved in mycarose biosynthesis (322 aa), fasta FT scores; opt: 174 z-score: 200.8 E(): 0.00073, 28.7% FT identity in 282 aa overlap" FT /db_xref="GOA:Q9X7U0" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9X7U0" FT /protein_id="CAB42958.1" FT /translation="MSAATPQPPAPHVVLGSGPAGTALARELVRRGHPVRLVDRRATGP FT AVEGVERFPADVGTADGARAAIRDAAVVYHCVNVAYHLQVEVMPRVQEAVLAAVEESGA FT RLVVLDTVYPYGETGGAVMTEDSPWKATSRKGRMRAELDERYLAAHRSGRARVVLGRSA FT DFVGPGVLNSSLGAAVFPGALTGGDVVAMGNIDLPHSYTGIEDVAAALATLGERPDGDG FT RVWHLPTAPAVSTREIHALIEKRVGRPLNVVVLERPRPFGPFDEQLMAEYEEMFYQHTE FT AQIMDSGAFERFFEAAPTPLADTLDATVTWYEAWLRSR" FT CDS complement(9805..10074) FT /transl_table=11 FT /gene="SCO7260" FT /gene_synonym="SC5H1.32" FT /product="possible membrane protein" FT /note="SC5H1.32, possible membrane protein, len: 89 aa; FT unknown function, similar to e.g. SW:YEAQ_ECOLI FT (EMBL:AE000274), yeaQ, Escherichia coli hypothetical FT protein (82 aa), fasta scores; opt: 180 z-score: 242.2 E(): FT 3.6e-06, 35.2% identity in 71 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9X7T9" FT /protein_id="CAB42957.1" FT /translation="MEIDGIVSAIVIGVVIGVLGRLVVPGRQRIGVVWTILVGIVAALV FT GSWVASAFDVADTDGVDWVEWLIQIGLAAVGVAALDRSRSRPGR" FT RBS complement(10082..10086) FT /note="possible RBS" FT CDS complement(10211..10654) FT /transl_table=11 FT /gene="SCO7261" FT /gene_synonym="SC5H1.31" FT /product="putative membrane protein" FT /note="SC5H1.31, possible membrane protein, len: 147 aa; FT unknown function, similar to TR:O07432 (EMBL:Z97050) FT Mycobacterium tuberculosis hypothetical protein (143 aa), FT fasta scores; opt: 326 z-score: 414.4 E(): 9.2e-16, 36.2% FT identity in 141 aa overlap" FT /db_xref="InterPro:IPR005530" FT /db_xref="UniProtKB/TrEMBL:Q9X7T8" FT /protein_id="CAB42956.1" FT /translation="MANVSHSRGDITSHPDAPEMQARYARVLGGRDVALVDGPVFLLGL FT YCAVSPWILHFTTSQPSLVAHNLIVGVAIGLLALGFTRAPERMYGLSWAMCAIGVWMII FT SPWIVGSSPDAGVIWNNIVIGALALLLGMVCAGTAARSAPRRP" FT misc_feature 10320..12621 FT /note="sequence corresponding to EMBL:AB017012 from 2300 to FT 1" FT RBS complement(10662..10666) FT /note="possible RBS" FT CDS 10945..11109 FT /transl_table=11 FT /gene="SCO7262" FT /gene_synonym="SC5H1.30c" FT /product="hypothetical protein" FT /note="SC5H1.30c, hypothetical protein, len: 54 aa; unknown FT function, possible short CDS suggested by positional base FT preference, GC frame analysis and amino acid composition" FT /db_xref="UniProtKB/TrEMBL:Q9X7T7" FT /protein_id="CAB42955.1" FT /translation="MVPLDVRTLPARARLGADLGHPAITESAGLFARPDVVAGAPVRKA FT SYSGALNAS" FT CDS 11282..12172 FT /transl_table=11 FT /gene="SCO7263" FT /gene_synonym="SC5H1.29c" FT /gene_synonym="chiF" FT /product="chitinase" FT /note="SC5H1.29c, chiF, chitinase, len: 296 aa; previously FT sequenced as chiF (EMBL:AB017012) and similar to many e.g. FT TR:O50152 (EMBL:AB009289), chiC, Streptomyces griseus FT chitinase C (294 aa), fasta scores; opt: 1308 z-score: FT 1506.5 E(): 0, 65.8% identity in 295 aa overlap. Contains FT possible N-terminal signal sequence. Contains Pfam match to FT entry PF00182 chitinase_1, Chitinases class I, score FT 247.20, E-value 2.2e-70" FT /db_xref="GOA:Q9S6T0" FT /db_xref="HSSP:1CNS" FT /db_xref="InterPro:IPR000726" FT /db_xref="UniProtKB/TrEMBL:Q9S6T0" FT /protein_id="CAB42954.1" FT /translation="MSRRRISAVVTALALAGAVPLLMPANEASAASCSSYHAWSADANY FT NTGDIVRYTDGKAYIAEHANPGYDPLISTWYWDPYACDGGSQTPVGNFVVSEAQFNQMF FT PGRNSFYTYSGLTAALSAYPGFANTGSDTTKKQEAAAFLANVSHETGGLVYIVEQNTAN FT YPHYCDWNQPYGCPAGQAAYYGRGPIQLSWNFNYKAAGDALGIDLLGNPWLVQNDAAVA FT WKTGLWYWNTQSGPGTMTPHNAMVNGAGFGQTIRSINGSLECDGKNPAQVQSRVTKYQQ FT FAQILGVSPGGNLYC" FT misc_feature 11561..12169 FT /note="Pfam match to entry PF00182 chitinase_1, Chitinases FT class I, score 247.20, E-value 2.2e-70" FT CDS 12183..13100 FT /transl_table=11 FT /gene="SCO7264" FT /gene_synonym="SC5H1.28c" FT /product="putative oxidoreductase" FT /note="SC5H1.28c, probable oxidoreductase, len: 305 aa; FT similar to many e.g. SW:MORA_PSEPU (EMBL:Q02198), morA, FT Pseudomonas putida morphine 6-dehydrogenase (295 aa), fasta FT scores; opt: 235 z-score: 281.5 E(): 2.3e-08, 28.1% FT identity in 274 aa overlap" FT /db_xref="GOA:Q9X7T6" FT /db_xref="HSSP:1HW6" FT /db_xref="InterPro:IPR020471" FT /db_xref="UniProtKB/TrEMBL:Q9X7T6" FT /protein_id="CAB42953.1" FT /translation="MCETPPMTSETITAESAGTWHLGDLPVRRVGFGAMRLTGSAAFHL FT GTPSDRARSLAVLRRAVELGVNHIDTAAFYFSSLRSANELINSALAPYADDLVIATKVG FT PYRDWSGEWGTSARPEDLRAHVEENLRQLGRDHLDVVYLRRMRQDSVAEHFGALAELRA FT AGLIRHLGLSGVEPRHLAEAQAIAPVMSVQNRYGLGFHDPATDALLAQCRAQGIAFVPF FT YAIAGEAGPRGAGTAHEEEVRAVARAHGASSAQVRIAWTLHQGPHVLAVPGTGNPDHLA FT ENVAAGALRLTGADLARLDGARTG" FT CDS complement(13475..14074) FT /transl_table=11 FT /gene="SCO7265" FT /gene_synonym="SC5H1.27" FT /product="hypothetical protein" FT /note="SC5H1.27, hypothetical protein, len: 199 aa; unknown FT function, probable CDS suggested by positional base FT preference, GC frame analysis and amino acid composition" FT /db_xref="UniProtKB/TrEMBL:Q9X7T5" FT /protein_id="CAB42952.1" FT /translation="MTPNRRPRPSGAEVRRKIRGPDGLALLPSGRVSWLPDDFVHPVLV FT PLPGGDHHLRPIRETDTPLDYPAVMGSRERLWTVYGPAWGWPAATMTYEADRADLLRHE FT KEIAAHQSFNYALFDTAETALLGCVYIDPPERAGADGDISWWVVDELVDSTVERALDAL FT VPQWIAADWPFERPRFIGREISWSDYLALPGIPTVP" FT CDS complement(14071..14808) FT /transl_table=11 FT /gene="SCO7266" FT /gene_synonym="SC5H1.26" FT /product="putative 3-oxoacyl-[acyl-carrier protein] FT reductase" FT /note="SC5H1.26, probable 3-oxoacyl-[acyl-carrier protein] FT reductase, len: 245 aa; similar to many short-chain FT oxidoreductases e.g. SW:FABG_BACSU (EMBL:U59433), FabG, FT Bacillus subtilis 3-oxoacyl-[acyl-carrier protein] FT reductase (246 aa), fasta scores; opt: 521 z-score: 562.5 FT E(): 5.2e-24, 36.6% identity in 246 aa overlap and FT SW:DHG2_BACME (EMBL:D90044), GdhII, Bacillus megaterium FT glucose 1-dehydrogenase II (261 aa) (35.3% identity in 249 FT aa overlap). Similar to SCE134.03c (EMBL:AL049661) possible FT short chain dehydrogenase (255 aa) (35.1% identity in 242 FT aa overlap). Contains Pfam matches to entry PF00106 FT adh_short, short chain dehydrogenase, score 220.40, E-value FT 2.7e-62 and entry PF00678 adh_short_C2, Short chain FT dehydrogenase/reductase C-terminus, score 44.40, E-value FT 2.6e-09" FT /db_xref="GOA:Q9X7T4" FT /db_xref="HSSP:1G0N" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9X7T4" FT /protein_id="CAB42951.1" FT /translation="MLEDMTAVVTGGSRGIGRAIVERLCSDGADVVFNYSTGEEAAADV FT VRTVRANGGEVRAMRLDLREPDAAERLMEDAEAHLGSVDILVNNAATSFTPAPLAETEA FT EVFDGVLAANTRSVFLTMRYAARRMRDGGRIVNISTLNTVRPVPGIGPYAASKGAIEQL FT TAVAARELGPRGITVNTVSPGATDTDLLRGTNPPEALQAVVGMTPLGRLGQPSDVADVV FT AFLVGPGGGWITGQNLRATGGLA" FT misc_feature complement(14089..14181) FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 44.40, FT E-value 2.6e-09" FT misc_feature complement(14242..14796) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 220.40, E-value 2.7e-62" FT CDS 15041..15436 FT /transl_table=11 FT /gene="SCO7267" FT /gene_synonym="SC5H1.25c" FT /product="conserved hypothetical protein" FT /note="SC5H1.25c, conserved hypothetical protein, len: 131 FT aa; similar to e.g. SW:YFC3_SHEPU (EMBL:L04283) Shewanella FT putrefaciens hypothetical protein (118 aa), fasta scores; FT opt: 372 z-score: 466.1 E(): 1.2e-18, 52.2% identity in 115 FT aa overlap. Weakly similar to some lyases e.g. FT SW:LGUL_SALTY (EMBL:U57364), gloA, Salmonella typhimurium FT lactoylglutathione lyase (135 aa) (23.6% identity in 127 aa FT overlap). Also similar to TR:O86701 (EMBL:AL031515) FT S.coelicolor possible lyase (138 aa) (33.1% identity in 127 FT aa overlap)" FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/TrEMBL:Q9X7T3" FT /protein_id="CAB42950.1" FT /translation="MTRIALVALVVDDYDEAIRFYTEALGFRLAEDTPRPDGSRWVVVE FT PGGPDAGTALLLARAKGEAQRARVGDQTGGRVGFFLHTDDFARDHARMTAAGVTFLEEP FT RHEPYGSVAVFQDLYGNRWDLLQPVAP" FT CDS 15471..16550 FT /transl_table=11 FT /gene="SCO7268" FT /gene_synonym="SC5H1.24c" FT /gene_synonym="add" FT /product="putative adenosine deaminase" FT /note="SC5H1.24c, add, probable adenosine deaminase, len: FT 359 aa; similar to many e.g. SW:ADD_ECOLI (EMBL:M59033), FT Add, Escherichia coli adenosine deaminase (333 aa), fasta FT scores; opt: 369 z-score: 434.3 E(): 7.2e-17, 32.8% FT identity in 338 aa overlap. Weakly similar to TR:O86737 FT (EMBL:AL031035) S.coelicolor possible adenosine deaminase FT (387 aa) (28.9% identity in 342 aa overlap). Contains Pfam FT match to entry PF00962 A_deaminase, Adenosine/AMP FT deaminase, score 220.40, E-value 2.6e-62" FT /db_xref="GOA:Q9X7T2" FT /db_xref="HSSP:1KRM" FT /db_xref="InterPro:IPR006330" FT /db_xref="UniProtKB/Swiss-Prot:Q9X7T2" FT /protein_id="CAB42949.1" FT /translation="MSSTRIDTETLRRLPKAVLHDHLDGGLRPATVVELARSVGHTLPT FT TDPDELAAWYYEAANSGDLVRYIATFEHTLAVMQNREGLLRAAEEYVLDLAADGVVYGE FT VRYAPELNTRGGLSMREVVETVQEGLATGMAKAAAAGTPVRVGTLLCGMRMFDRVREAA FT DLAVAFRDAGVVGFDIAGAEDGFPPADHLDAFEHLRRENVPFTIHAGEAHGLPSIHQAL FT QVCGAQRIGHGVRITDDIPDLAAGKLGRLAAWVRDRRIALEMCPTSNLQTGAATSIAEH FT PITALKDLGFRVTLNTDNRLVSGTTMTREMSLLVEQAGWSVEDLRTVTVNALKSAFVPF FT DERTALIEDVVLPAYASVL" FT misc_feature 15666..16517 FT /note="Pfam match to entry PF00962 A_deaminase, FT Adenosine/AMP deaminase, score 220.40, E-value 2.6e-62" FT CDS complement(16532..17047) FT /transl_table=11 FT /gene="SCO7269" FT /gene_synonym="SC5H1.23" FT /product="conserved hypothetical protein" FT /note="SC5H1.23, hypothetical protein, len: 171 aa; unknown FT function, similar to TR:O53728 (EMBL:AL021932) FT Mycobacterium tuberculosis hypothetical protein (171 aa), FT fasta scores; opt: 561 z-score: 716.6 E(): 1.4e-32, 49.7% FT identity in 165 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9X7T1" FT /protein_id="CAB42948.1" FT /translation="MHAKDILIEGYGRIQEEVHAAVEGLDPDGLNARPAAGANSVAWLV FT WHLTRVQDDHVADAFGLDQVWLTGEWEKRFGLGLPRRDTGYGHSPAEVAKVRVDSGELL FT TGYYDAVHEQTLTALRSLTAKDLERVVDDNWDPPVTLAVRLVSVLSDDLQHVGQAAYVR FT GLVQSTEA" FT CDS complement(17088..17972) FT /transl_table=11 FT /gene="SCO7270" FT /gene_synonym="SC5H1.22" FT /product="putative transcriptional regulator" FT /note="SC5H1.22, probable transcriptional regulator, len: FT 294 aa; similar to many LysR family regulators e.g. FT SW:BUDR_KLETE (EMBL:Z48600), budR, Klebsiella terrigena bud FT operon transcriptional regulator (290 aa), fasta scores; FT opt: 392 z-score: 459.0 E(): 3.1e-18, 33.7% identity in 267 FT aa overlap. Similar to TR:O86805 (EMBL:AL031317) FT S.coelicolor probable transcriptional regulator (306 aa) FT (29.3% identity in 304 aa overlap). Contains probable FT helix-turn-helix motif at aa 17-38 (Score 1145, +3.09 SD). FT Contains Pfam match to entry PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix proteins, lysR family, score FT 171.10, E-value 1.9e-47 and PS00044 Bacterial regulatory FT proteins, lysR family signature" FT /db_xref="GOA:Q9X7T0" FT /db_xref="HSSP:1IXC" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9X7T0" FT /protein_id="CAB42947.1" FT /translation="MELRHLQHFVAVAEDQHFTRAAERLLVSQSGLSASIRALERELRA FT PLFVRTTRRVTLTEAGRALLEEARRILAQVRSAHEAVAAVQGVLRGTLSLGAEQCIAGV FT PVARLLAAFRRGHPDVEIRLRQAGSGELAEEVAAGRLDLAFAYRTQADTDQLRSVSLAG FT EPMTVLCHPDHRLAADGAVLTPHDLADEVFVDFHPDWGPRRVTDAVFAAAGVRRTVPLE FT VNDVHGLLDLIDENLGIAVVPRHFRHKRAALTSLPLKDADGTEYETIALLPSARATSPA FT ARALMGLLETGSA" FT misc_feature complement(17538..17966) FT /note="Pfam match to entry PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix proteins, lysR family, score FT 171.10, E-value 1.9e-47" FT misc_feature complement(17832..17924) FT /note="PS00044 Bacterial regulatory proteins, lysR family FT signature" FT RBS 18130..18133 FT /note="possible RBS" FT CDS 18134..19093 FT /transl_table=11 FT /gene="SCO7271" FT /gene_synonym="SC5H1.21c" FT /product="putative ion channel subunit" FT /note="SC5H1.21c, probable ion channel subunit, len: 319 FT aa; similar to many eukaryotic potassium channel subunits FT e.g. TR:Q39151 (EMBL:L40948) Arabidopsis thaliana K+ FT channel protein (328 aa), fasta scores; opt: 627 z-score: FT 726.8 E(): 0, 35.7% identity in 325 aa overlap. Weakly FT similar to SC5H1.06c, hypothetical protein (327 aa) (29.3% FT identity in 338 aa overlap)" FT /db_xref="GOA:Q9X7S9" FT /db_xref="HSSP:1GVE" FT /db_xref="InterPro:IPR001395" FT /db_xref="UniProtKB/TrEMBL:Q9X7S9" FT /protein_id="CAB42946.1" FT /translation="MPYRRTGRSGLKLPALSLGLWHNFGPDRPVETQRAILRRAFDLGV FT THFDLANNYGPPPGSAESALGEALKADFAPYRDELVISTKAGYLMWPGPYGEWGSRKSL FT LSSLDQSLSRMGLEYVDVFYSHRPDPKTPLEETMGALHTAVQQGKALYVGVSNYSPEQT FT REAARILAELGTPLLIHQPRYSMLDRRPETGGLLDALDELEVGSIAYSPLEQGLLTGRY FT LNGIPEDSRAASDSPFLNSDAVTEELVGKLRGLNEIAGSRGQSLAQLALAWVLRQGRVT FT SALVGASSPRQLEDSVAAIGNLDFDADELARIDKIVQG" FT stem_loop complement(19100..19172) FT /note="stem is 27/34 (79%) matches, 0 gaps; loop is 5 bp" FT CDS complement(19175..19558) FT /transl_table=11 FT /gene="SCO7272" FT /gene_synonym="SC5H1.20" FT /product="putative isomerase" FT /note="SC5H1.20, possible isomerase, len: 127 aa; weakly FT similar to SW:SDIS_PSEPU (EMBL:L13127), ksI, Pseudomonas FT putida steroid delta-isomerase (131 aa), fasta scores; opt: FT 109 z-score: 150.4 E(): 0.47, 26.0% identity in 131 aa FT overlap" FT /db_xref="GOA:Q9X7S8" FT /db_xref="UniProtKB/TrEMBL:Q9X7S8" FT /protein_id="CAB42945.1" FT /translation="MSAPTRRYEDAVARYFEAWNAGPDAVAKAVAAAWTEDGGYTDPLA FT DVRGHERIAAVIVAAHEQFPGFSFRLAGPVDGHHDTARFSWELVSDAEEGLAPVAGFDV FT ITLDGEDRIRSVFGFLDRVPAGA" FT CDS 19893..20303 FT /transl_table=11 FT /gene="SCO7273" FT /gene_synonym="SC5H1.19c" FT /product="hypothetical protein" FT /note="SC5H1.19c, hypothetical protein, len: 136 aa; FT unknown function, probable CDS suggested by positional base FT preference, GC frame analysis and amino acid composition. FT Contains TTA (leucine) codon, possible target for bldA FT regulation" FT /db_xref="UniProtKB/TrEMBL:Q9X7S7" FT /protein_id="CAB42944.1" FT /translation="MHDEFLCHVTAYGVCDGRRIGVPLGTYRAPTLALALWWLRDRAMW FT IAERLDPQPDTPHLPRGALTPVADDAPDVPLRLRAWCADDVQQELVADELAAGNLVRLA FT TSDETTEYELMAESVDALRMQRAAPPLVVPVA" FT misc_feature 20067..20069 FT /note="TTA (leucine) codon, possible target for bldA FT regulation" FT CDS complement(20329..21531) FT /transl_table=11 FT /gene="SCO7274" FT /gene_synonym="SC5H1.18" FT /product="putative membrane protein" FT /note="SC5H1.18, possible membrane protein, len: 400 aa; FT unknown function, probable CDS suggested by positional base FT preference, GC frame analysis and amino acid composition. FT Contains hydrophobic, probable membrane-spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9X7S6" FT /protein_id="CAB42943.1" FT /translation="MLAGLVAMGGVAALGLWAAGAADLPDRAFPRVVVATFVTSVGGAV FT EMSGDAGELAATDAGLTVMPLSVTLTGALVIARGFLRPLRHRAVVGARELAGWAGRIAV FT LWLLALLGAGFAARQTFEVSLGEGLLSDLGDLFGVRPTVGFTTDLPLTVLFGLLWLAGV FT LVLALLVSHRAPLPGRLPGLRTSVRPAAYAMVALLLAYVVVGVVVALVVAATRDRPADT FT FAVLLLGLPNLAWPALTIGLGATWNGRVEGPFGLPMPRVLDEVLRTPDVSTVNVGTLAE FT RDGRMWWLLVAAAVLVLSAGFLMASRCPARLPAWLHAVRLAVALALTVLMIGLVGRVSA FT HYGLSVLGIGDLGGGLAGQVFLRPRLWGAVGLALLWGLVAGFLGSLLARWAGGRSRRVR FT H" FT CDS complement(21750..22169) FT /transl_table=11 FT /gene="SCO7275" FT /gene_synonym="SC5H1.17" FT /product="hypothetical protein" FT /note="SC5H1.17, hypothetical protein, len: 138 aa; unknown FT function, probable CDS suggested by positional base FT preference, GC frame analysis and amino acid composition. FT Contains region similar to adjacent CDS SC5H1.16, FT hypothetical protein (194 aa) (34.6% identity in 107 aa FT overlap)" FT /db_xref="UniProtKB/TrEMBL:Q9X7S5" FT /protein_id="CAB42942.1" FT /translation="MMLFTEVCGLPVMPQEGTAPLGTVTSLDVDVVSGTVSHVRWRGGR FT FRRETALPWDAVHTVGPGAVRVRSAALEPVPPHHDHELLGRRILTETGTERGTVLDVAF FT DTLSARLLALFTTRGELPPGRLLGLGDYALVVRAV" FT CDS complement(22166..22750) FT /transl_table=11 FT /gene="SCO7276" FT /gene_synonym="SC5H1.16" FT /product="hypothetical protein" FT /note="SC5H1.16, hypothetical protein, len: 194 aa; unknown FT function, probable CDS suggested by positional base FT preference, GC frame analysis and amino acid composition. FT Start codon position suggested by GC frame plot and FT possible RBS. Contains region similar to adjacent CDS, FT SC5H1.17, hypothetical protein (138 aa) (34.6% identity in FT 107 aa overlap)" FT /db_xref="InterPro:IPR007903" FT /db_xref="UniProtKB/TrEMBL:Q9X7S4" FT /protein_id="CAB42941.1" FT /translation="MDELMAARSLTTRPVVTLGGDAVAHVKDTVCDAAAERITGFTLTG FT RGLLSGPLKEGLPWSAVYALGHDAVMIRDRRGLVNAAAMTAHQQNLRARLRGARVLTEA FT GTEIGTVLDVVVEGGTGGRVVGFRVAASRRFVPGPTRHRRRVYVPRGRTLTVSGRALVL FT PDGAVRHVADDLPGFTALVGGVPGPWQESLP" FT RBS complement(22758..22763) FT /note="possible RBS" FT CDS 22920..23375 FT /transl_table=11 FT /gene="SCO7277" FT /gene_synonym="SC5H1.15c" FT /product="putative regulator protein" FT /note="SC5H1.15c, possible regulator protein, len: 151 aa; FT similar to Streptomyces fradiae beta-lactamase regulator FT protein (EMBL:AB024056) (139 aa), fasta scores; opt: 177 FT z-score: 241.8 E(): 3.8e-06, 35.2% identity in 122 aa FT overlap and TR:O54111 (EMBL:AL021529), SC10A5.20, FT S.coelicolor hypothetical protein (171 aa) (35.4% identity FT in 99 aa overlap)" FT /db_xref="GOA:Q9X7S3" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9X7S3" FT /protein_id="CAB42940.1" FT /translation="MTEYLDGAVIPTGFDVPVEPLRRAAHYSGEPGCIAQARSFASLFL FT DQLRTEWCATIGPRADGAVLLVVSELVTNADRHSRGPYILELEGTGASVAVTVYDSSGA FT VPERFPRDPERIGQHGLEIVHALVETVVVERVPVGKRVRAVVPLTEG" FT stem_loop complement(23346..23391) FT /note="stem is 18/19 (94%) matches, 0 gaps; loop is 8 bp" FT CDS complement(23400..24287) FT /transl_table=11 FT /gene="SCO7278" FT /gene_synonym="SC5H1.14" FT /product="putative RNA polymerase sigma factor" FT /note="SC5H1.14, probable RNA polymerase sigma factor, len: FT 295 aa; similar to many e.g. SW:RPOF_STRCO (EMBL:L11648), FT SigF, RpoX, Streptomyces coelicolor RNA polymerase sigma-F FT factor (287 aa), fasta scores; opt: 707 z-score: 817.4 E(): FT 0, 43.6% identity in 282 aa overlap. Contains probable FT helix-turn-helix motif at aa 258-279 (Score 2096, +6.33 FT SD). Contains Pfam match to entry PF00140 sigma70, Sigma-70 FT factors, score 230.40, E-value 2.6e-65 and PS00715 Sigma-70 FT factors family signature 1" FT /db_xref="GOA:Q9X7S2" FT /db_xref="HSSP:1L0O" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9X7S2" FT /protein_id="CAB42939.1" FT /translation="MQTAVVRPQAQVAGKTAGSGTGEGSARDVVDPRSVAPRDARQLSR FT QFFRRLTELEEGTAEYQFARNTLIEMNMSLVRFAAGRFRGRGNDMEDIVQTGMIGLIKA FT IDRFELSREVEFTSFALPYIVGEIKRFFRDTTWAVHVPRRLQELRVELARAREELSTRL FT DREPTVAELATLMNIGEDQVIEGQIASNGYNSSSLDAALTGDGPENGESVLADFIGVEE FT DGLRLVEDFHSLAPLMAELSERDRQIIHLRFVEEATQAEIGERLGCSQMHVSRLIKRII FT TRLREGMLGELGCA" FT misc_feature complement(23430..24104) FT /note="Pfam match to entry PF00140 sigma70, Sigma-70 FT factors, score 230.40, E-value 2.6e-65" FT misc_feature complement(23973..24014) FT /note="PS00715 Sigma-70 factors family signature 1" FT RBS 24490..24495 FT /note="possible RBS" FT CDS 24495..24968 FT /transl_table=11 FT /gene="SCO7279" FT /gene_synonym="SC5H1.13c" FT /product="possible DNA-binding protein" FT /note="SC5H1.13c, possible DNA-binding protein, len: 157 FT aa; contains region similar to TR:O33287 (EMBL:AL008967) FT Mycobacterium tuberculosis possible transcriptional FT regulator (112 aa), fasta scores; opt: 254 z-score: 260.9 FT E(): 3.3e-07, 50.0% identity in 94 aa overlap and TR:O86815 FT (EMBL:AL031031), SC7C7.10, S.coelicolor hypothetical FT protein (126 aa) (55.6% identity in 72 aa overlap). FT Possible DNA-binding function as it contains probable FT helix-turn-helix motif at aa 77-98 (Score 1354, +3.80 SD) FT and Pfam match to entry PF01381 HTH_3, Helix-turn-helix, FT score 41.30, E-value 2.2e-08. PQATR repeat present in FT proline-rich N-terminus" FT /db_xref="GOA:Q9X7S1" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q9X7S1" FT /protein_id="CAB42938.1" FT /translation="MTSHVPNEARVIPLRPQATRPQATRPQAARPQATRPGARPAASPV FT PPERRPPAAREPLWRDLVGDVLRRERLEQERTLKEVAEAARISMPYLSEVERGRKEASS FT EVLAAAAGALGLGLGDLLARAQGELVRLTSRHTGPGAGRGASGARFDGMCLAA" FT misc_feature 24693..24857 FT /note="Pfam match to entry PF01381 HTH_3, Helix-turn-helix, FT score 41.30, E-value 2.2e-08" FT CDS complement(25020..25622) FT /transl_table=11 FT /gene="SCO7280" FT /gene_synonym="SC5H1.12" FT /gene_synonym="clpP4" FT /product="putative ATP-dependent Clp protease proteolytic FT subunit 2" FT /note="SC5H1.12, clpP4, probable ATP-dependent Clp protease FT proteolytic subunit 2, len: 200 aa; similar to many e.g. FT clpP2 (EMBL:AF071885) Streptomyces coelicolor ATP-dependent FT Clp protease proteolytic subunit 2 (236 aa), fasta scores; FT opt: 716 z-score: 853.7 E(): 0, 56.0% identity in 193 aa FT overlap. Also similar to adjacent CDS, SC5H1.11, probable FT ATP-dependent Clp protease proteolytic subunit 1 (217 aa) FT (39.3% identity in 201 aa overlap). Contains Pfam match to FT entry PF00574 CLP_protease, Clp protease, score 268.60, FT E-value 8.1e-77" FT /db_xref="GOA:Q9X7S0" FT /db_xref="HSSP:1TYF" FT /db_xref="InterPro:IPR018215" FT /db_xref="UniProtKB/Swiss-Prot:Q9X7S0" FT /protein_id="CAB42937.1" FT /translation="MGSYTIPNVVERTPQGERSYDVFSRLLSERIIFLGTEIDDGVANV FT VIAQLLHLESSAPESEIAVYINSPGGSFTSLMAIYDTMTFVQAPISTFCVGQAASTAAV FT LLAGGDPGRRFVLEHARVLLGQPASGGRQGTVSDLALQAKEMVRIRSQVEEVLARHTHH FT DVATLRADMDRDKVFTAQEAVAYGLADEVLARRLTRV" FT misc_feature complement(25038..25610) FT /note="Pfam match to entry PF00574 CLP_protease, Clp FT protease, score 268.60, E-value 8.1e-77" FT CDS complement(25624..26277) FT /transl_table=11 FT /gene="SCO7281" FT /gene_synonym="SC5H1.11" FT /gene_synonym="clpP3" FT /product="putative ATP-dependent Clp protease proteolytic FT subunit 1" FT /note="SC5H1.11, clpP3, probable ATP-dependent Clp protease FT proteolytic subunit 1, len: 217 aa; similar to many e.g. FT clpP1 (EMBL:AF071885) Streptomyces coelicolor ATP-dependent FT Clp protease proteolytic subunit 1 (218 aa), fasta scores; FT opt: 683 z-score: 806.7 E(): 0, 57.6% identity in 177 aa FT overlap. Also similar to adjacent CDS, SC5H1.12, probable FT ATP-dependent Clp protease proteolytic subunit 2 (200 aa) FT (39.3% identity in 201 aa overlap). Contains Pfam match to FT entry PF00574 CLP_protease, Clp protease, score 281.20, FT E-value 1.3e-80 and PS00382 Endopeptidase Clp histidine FT active site" FT /db_xref="GOA:Q9X7R9" FT /db_xref="HSSP:1TYF" FT /db_xref="InterPro:IPR018215" FT /db_xref="UniProtKB/Swiss-Prot:Q9X7R9" FT /protein_id="CAB42936.1" FT /translation="MSPFTAGPAPARTPRAEEGDTPATRFDDRLAEQLLDQRIVLLGTQ FT VDEVSANRVCAQLLILSAQDPRTDISLYVNSPGGSVHAGLAIYDTMRLIPNDVSTLAMG FT FAASMGQFLLSVGTAGKRYALPNARIMMHQPSAGIGGTTADIEIQADNLDFTKRTIERI FT TAEHTGQSPETISRDGDRDRWFTAEEAREYGMVDQVVQSLADVRPAATRRRMGL" FT misc_feature complement(25672..26265) FT /note="Pfam match to entry PF00574 CLP_protease, Clp FT protease, score 281.20, E-value 1.3e-80" FT misc_feature complement(25873..25914) FT /note="PS00382 Endopeptidase Clp histidine active site" FT RBS 26486..26490 FT /note="possible RBS" FT CDS 26496..26978 FT /transl_table=11 FT /gene="SCO7282" FT /gene_synonym="SC5H1.10c" FT /product="putative DNA-binding protein" FT /note="SC5H1.10c, hypothetical protein, len: 160 aa; FT unknown function, probable CDS suggested by positional base FT preference, GC frame analysis, amino acid composition and FT the presence of a possible RBS; similar to TR:Q98C01 FT (EMBL:AP003006) Rhizobium loti (Mesorhizobium loti) MLL5357 FT protein, 156 aa; fasta scores: opt: 617 Z-score: 752.0 E(): FT 2.9e-34; 58.170% identity in 153 aa overlap. Contains FT probable helix-turn-helix motif at aa 104-125 (Score 1006, FT +2.61 SD)" FT /db_xref="GOA:Q9X7R8" FT /db_xref="InterPro:IPR009725" FT /db_xref="UniProtKB/TrEMBL:Q9X7R8" FT /protein_id="CAB42935.1" FT /translation="MSTDGFTTCLWFDGDAEDAAHFYVSVFKNSGIGAVTRYPEGAPQP FT AGSVLTVEFTANGQKFVGLNGGPQFKFNEAISFQVTCEDQDEVDHYWTRLTEGGGEDGP FT CGWLKDRFGVSWQVVPRRLEEMFRDPDPARVARANKAMMSMRKLDIAALEQAYAGE" FT RBS 27092..27097 FT /note="possible RBS" FT CDS 27106..27903 FT /transl_table=11 FT /gene="SCO7283" FT /gene_synonym="SC5H1.09c" FT /product="putative hydroxylase" FT /note="SC5H1.09c, possible hydroxylase, len: 265 aa; FT similar to e.g. TR:Q55078 (EMBL:U50973), doxA, Streptomyces FT sp. daunomycin C-14 hydroxylase (275 aa), fasta scores; FT opt: 440 z-score: 519.4 E(): 1.3e-21, 37.5% identity in 259 FT aa overlap. Similar to SC9B10.20c (EMBL:AL009204) FT S.coelicolor hypothetical protein (267 aa) (34.1% identity FT in 249 aa overlap)" FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/TrEMBL:Q9X7R7" FT /protein_id="CAB42934.1" FT /translation="MAVQPQGAPCWADAMFTDVEGAKSFYGDVLGWTFGESSTEFGNYT FT QCYADGKAVAAVVPPPPGHEDQSQWCLYFASPDAAATAGRIREAGGELLLEPMKVGDFG FT TMCLARDPSGVVFGVWQGDEHEGFEATAVPGAYCWAEVFTREPAKSDAFFPAVFSYRAR FT QMQDDQVDFRLFDLGDDPVLGRMAMTEDFPPEVPPHINVYFTVGDCDAAVARATERGGM FT LRFGPVTTPFGRFAALSDPQGASFSVIDITTTEGEMPEVTDVS" FT CDS 27935..28642 FT /transl_table=11 FT /gene="SCO7284" FT /gene_synonym="SC5H1.08c" FT /gene_synonym="rnhA" FT /product="putative ribonuclease H" FT /note="SC5H1.08c, rnhA, probable ribonuclease H, len: 235 FT aa; similar to many e.g. SW:RNH_THETH (EMBL:X60507), rhnA, FT Thermus aquaticus ribonuclease H (166 aa), fasta scores; FT opt: 299 z-score: 312.2 E(): 4.6e-10, 38.0% identity in 166 FT aa overlap. Also similar to TR:Q54388 (EMBL:X95703), rnhH, FT Streptomyces lincolnensis putative ribonuclease H (117 aa) FT (89.7% identity in 117 aa overlap). Has a C-terminal FT extension not present in the Thermus aquaticus enzyme. FT Contains Pfam match to entry PF00075 rnaseH, RNase H, score FT 52.60, E-value 8.9e-12" FT /db_xref="GOA:Q9X7R6" FT /db_xref="HSSP:1RIL" FT /db_xref="InterPro:IPR002156" FT /db_xref="UniProtKB/Swiss-Prot:Q9X7R6" FT /protein_id="CAB42933.1" FT /translation="MIERMRERAVAACDGASKGNPGPAGWAWVVADASENPVRWEAGPL FT GKATNNIAELTALERLLASTDPDVPLEVRMDSQYAMKAVTTWLPGWKRNGWKTAAGKPV FT ANRELVVRIDELLDGRSVEFRYVPAHQVDGDRLNDFADRAASQAAVVQEAAGSALGSPE FT PPPAPDVPAARRAPRRGSSGAARKGGGGSSARTIKAKFPGRCLCGRPYAAGEPIAKNDQ FT GWGHPECRTVAAG" FT misc_feature 27950..28384 FT /note="Pfam match to entry PF00075 rnaseH, RNase H, score FT 52.60, E-value 8.9e-12" FT CDS 28745..30010 FT /transl_table=11 FT /gene="SCO7285" FT /gene_synonym="SC5H1.07c" FT /product="putative hydroxylase" FT /note="SC5H1.07c, possible hydroxylase, len: 421 aa; weakly FT similar to many e.g. TR:P96555 (EMBL:AB000564) Sphingomonas FT sp. salicylate hydroxylase (395 aa), fasta scores; opt: 188 FT z-score: 216.6 E(): 9.6e-05, 26.5% identity in 359 aa FT overlap and TR:Q53657 (EMBL:D38214), Cts8, Streptomyces FT aureofaciens 6-hydroxylation enzyme of tetracycline (469 FT aa) (25.9% identity in 347 aa overlap). Weakly similar to FT SCE29.14c (EMBL:AL035707) S.coelicolor possible salicylate FT hydroxylase (420 aa) (29.3% identity in 372 aa overlap). FT Contains Pfam match to entry PF01360 Monooxygenase, FT Monooxygenase, score 42.50, E-value 9.2e-09" FT /db_xref="GOA:Q9X7R5" FT /db_xref="InterPro:IPR003042" FT /db_xref="UniProtKB/TrEMBL:Q9X7R5" FT /protein_id="CAB42932.1" FT /translation="MCVKVACVGGGPAGLYLSILLKRQDPAHDVTVYERDPEGSTYGWG FT VTYWRGLLDRLRELDPGSARAVEEHSVRWRDGVAHVGGLATRHHGDEGFGIGRHRLLAI FT LAARARELGVRLEFEHPVTGANPPAADLVVAADGAGSALRTHHADHFGTEITGGRDHYV FT WLGTTKVFDAFTFAFVETDHGWIWAYGYGFGPEGSTCVVECAPGTWTGLGLDRADEAEG FT LGLLEKLFADVLDGHPLSARSSGRASAAWPVFRTLTNRTWSRDNLVLLGDAAHTTHYSI FT GAGTTLALEDAMALATALRERDTLPDALAHYERERRAALLPVQSAARLSAQWYENLPRY FT IHLPPEQMFALLGQRHSPLLPHLPPRLYYRIDRAAGRLETLRRVKRRLGPVIARTVQAR FT RLAAGDGRARSGRPDAVPAHRG" FT misc_feature 29129..29728 FT /note="Pfam match to entry PF01360 Monooxygenase, FT Monooxygenase, score 42.50, E-value 9.2e-09" FT CDS 30023..31006 FT /transl_table=11 FT /gene="SCO7286" FT /gene_synonym="SC5H1.06c" FT /product="putative oxidoreducatse" FT /note="SC5H1.06c, hypothetical protein, len: 327 aa; weakly FT similar e.g. SW:GS69_BACSU (EMBL:Y14082), YhdN, Bacillus FT subtilis general stress protein 69 (331 aa), fasta scores; FT opt: 419 z-score: 477.8 E(): 2.7e-19, 29.3% identity in 328 FT aa overlap and TR:Q40648 (EMBL:U46758), kob1, Oryza sativa FT potassium channel beta subunit protein (326 aa) (27.9% FT identity in 341 aa overlap). Weakly similar to SC5H1.21c, FT probable ion channel subunit (319 aa) (29.3% identity in FT 338 aa overlap)" FT /db_xref="GOA:Q9X7R4" FT /db_xref="HSSP:1LQA" FT /db_xref="InterPro:IPR001395" FT /db_xref="UniProtKB/TrEMBL:Q9X7R4" FT /protein_id="CAB42931.1" FT /translation="MDERTFGRSDQHASVIGLGTWQLGADWGDVDDKEALAVLEAAAES FT GVTFFDTADVYGDGRSEQTIATFLASRPDLHVLVATKMGRRVDQIPQNYVLDNFREWND FT RSRRNLGVDRLDLVQLHCPPTPVYSSDEVFDALDTLVEEERVAAYGVSVETCEEALTAI FT ARPNVASVQVILNPFRMKPLREVLPAAREAGVGIIARVPLASGLLTGKYTKDTVFAAND FT HRTFNRHGEAFDQGETFSGVDFATGVEAAAEFAALAPEGYTPAQLALRWIVQQPGVTSV FT IPGARSPEQARANTDAARLPELSEDTLAAIRDLYDRRVKDQVEGRW" FT CDS complement(31034..31387) FT /transl_table=11 FT /gene="SCO7287" FT /gene_synonym="SC5H1.05" FT /product="hypothetical protein" FT /note="SC5H1.05, hypothetical protein, len: 117 aa; unknown FT function, probable CDS suggested by positional base FT preference, GC frame analysis and amino acid composition" FT /db_xref="UniProtKB/TrEMBL:Q9X7R3" FT /protein_id="CAB42930.1" FT /translation="MSDTRLTVTLDGGGIDDARAIVRALEGVFGAPDGRPADEGATVHT FT ATFDAPDARHTPDASSAPAPGGALSAPVTVTVQGTPQAVEAASETLSRAFTARNEGAAS FT GDQERERQLLLVP" FT RBS complement(31397..31400) FT /note="possible RBS" FT RBS 31532..31536 FT /note="posisble RBS" FT CDS 31542..32045 FT /transl_table=11 FT /gene="SCO7288" FT /gene_synonym="SC5H1.04c" FT /product="possible membrane protein" FT /note="SC5H1.04c, possible membrane protein, len: 167 aa; FT unknown function, probable CDS suggested by positional base FT preference, GC frame analysis and the presence of a FT possible RBS; similar to TR:Q9AJX8 (EMBL:AL512944) FT Streptomyces coelicolor putative integral membrane protein FT SC8D11.43c, 184 aa; fasta scores: opt: 505 Z-score: 606.1 FT E(): 4e-26; 48.667% identity in 150 aa overlap. Contains FT hydrophobic, possible membrane-spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9X7R2" FT /protein_id="CAB42929.1" FT /translation="MRDAEAAEGSGRRRGRNETEEERADRMWTELIQEVRVAQMGVQIL FT FGFLLTVVFQPKYDTLSDTDQMIYLITVVLGAVTTGALIGPVSLHRLVSGRRVKPQAVR FT WASRLTVLGLVLLLATTACSLLLILRVATHDGFVPYLVTGVVLWYLLCWFGIPLWTRHR FT HTAR" FT CDS complement(32134..32562) FT /transl_table=11 FT /gene="SCO7289" FT /gene_synonym="SC5H1.03" FT /product="putative regulator" FT /note="SC5H1.03, possible regulator, len: 142 aa; similar FT to TR:P95753 (EMBL:D50051), ssgA, Streptomyces griseus gene FT involved in regulation of sporulation and cell division FT (136 aa), fasta scores; opt: 175 z-score: 240.4 E(): FT 4.6e-06, 32.5% identity in 120 aa overlap. Similar to FT SC5F2A.05c (EMBL:AL049587) S.coelicolor possible regulator FT (138 aa) (33.8% identity in 145 aa overlap)" FT /db_xref="InterPro:IPR006776" FT /db_xref="UniProtKB/TrEMBL:Q9X7R1" FT /protein_id="CAB42928.1" FT /translation="MNTVVHKTLVVQLQAGGTADRFPVLAHLAYDAADPFALTVVFSHD FT GRVLARWTLDREMVAEGLTRPVGVGDVRLRPESRGMWDELRIELLGDGRADGERHRAVV FT FVWAAAVEAFLRETHAVVRPGREEVRVDDFLAELTAEG" FT RBS complement(32568..32572) FT /note="possible RBS" FT CDS complement(32656..33633) FT /transl_table=11 FT /gene="SCO7290" FT /gene_synonym="SC5H1.02" FT /product="putative dehydrogenase" FT /note="SC5H1.02, probable dehydrogenase, len: 325 aa; FT similar to many e.g. TR:O68447 (EMBL:AF041061), fgd, FT Mycobacterium smegmatis F420-dependent glucose-6-phosphate FT dehydrogenase (336 aa), fasta scores; opt: 461 z-score: FT 553.9 E(): 1.6e-23, 33.4% identity in 335 aa overlap. FT N-terminus similar to N-terminus of SCD78.18c FT (EMBL:AL034355) S.coelicolor hypothetical protein (320 aa) FT (31.7% identity in 183 aa overlap)" FT /db_xref="GOA:Q9X7R0" FT /db_xref="InterPro:IPR019945" FT /db_xref="UniProtKB/TrEMBL:Q9X7R0" FT /protein_id="CAB42927.1" FT /translation="MAHIGYTMMTEQAGPRELVGHLVRAEEVGFDFSVTSDHYFPWLRA FT QGHSSYAWSVLGAAAQATSRIPLMTYVTCPTFRYHPAVVAQKAATLQLLSQGRFRLGLG FT SGENLNEHVVGGGWPSVDVRHEMLREAVEIIRALFGGRHVNRRGTHFDVESARLWDLPE FT SAPPIGIAVSGERSCELAGEFADLVIATEPKPELLEAFDRHGGGGKPRVGQLPVSYDPD FT RDTAIKRAHAQFRWFGSGWKVNSELPHPDAFEAATQFVTPDDVAESIPCGDDPDAFVAA FT VRPYVDAGFTEVALVQIGGESQPAFLDWSEKTLLPALREAFGRD" FT CDS complement(33690..35306) FT /transl_table=11 FT /gene="SCO7291" FT /gene_synonym="SC5H1.01" FT /gene_synonym="SC5F8.01c" FT /product="putative serine/threonine protein kinase" FT /note="SC5H1.01, probable serine/threonine protein kinase, FT partial CDS, len: >459 aa; similar to many eukaryotic-type FT e.g. SW:AFSK_STRCO (EMBL:D15062), afsK, Streptomyces FT coelicolor eukaryotic-type protein kinase involved in FT secondary metabolism (799 aa), fasta scores; opt: 261 FT z-score: 221.3 E(): 5.3e-05, 30.3% identity in 498 aa FT overlap and SW:KRCB_RAT (EMBL:D30041) Rattus norvegicus FT RAC-beta serine/threonine kinase (481 aa) (31.4% identity FT in 169 aa overlap). A hydrophobic region is present, so it FT is possible that the protein spans a membrane. Contains FT Pfam match to entry PF00069 pkinase, Eukaryotic protein FT kinase domain, score 30.80, E-value 1.9e-07" FT /note="SC5F8.01c, possible serine/threonine protein kinase, FT partials CDS, len:> 114 aa. Similar to many proposed FT Streptomyces coelicolor serine/threonine protein kinases FT e.g. TR:CAB82014(EMBL:AL161755) SCD63.07 (717 aa), fasta FT scores opt: 172 z-score: 222.0 E(): 6.8e-05 33.0% identity FT in 103 aa overlap. Overlaps and extends into CDS SC5H1.01 FT on the adjoining cosmid." FT /db_xref="GOA:Q8CJK5" FT /db_xref="InterPro:IPR017442" FT /db_xref="UniProtKB/TrEMBL:Q8CJK5" FT /protein_id="CAD55395.1" FT /translation="MGRAHVSTHELVAGRYRLFEVVQRETNRVCWSGEDATTGRPCLVT FT RIELPEGRAGEAARRAPGRVIRTGETMASLCPGRIAPVLDAVVADGMLWTVTEWVAGVP FT LGDLLDRRGAFGCARAARVGLELLAVLEAAHTHGVTHGELSPGQVFVREEGSVLVTGFG FT LAGATLAPRLTAPAYASPEQARDERIGPAADLWTLGAILYTMVEGRPPFRDRGRPEATL FT KGVDRLPLRTPVRAGPLAQAVTGLLRKNSRERPTRPVVRAALARALAEDPGTAVTEVTT FT GPGVRGGYAAARTAGRDRSRRTVAAGTALAVVTVAVAVLADLAVTDGLPGRGDGAAAGA FT RQRPSASAAPPTGSAPAAASPGSPSSPAGRPSASASPSKPGVPAPAGFRRYDAPEGFSV FT ALPEGWRRLDTASAPGGAYRVVFGASGDPRTLAVTYSRRAGADPVVVWRDDVEPGLARS FT DGYRRIGEIRSTTYRGRAAADMEWLVRDDGTRLRTFGRGFLLGGGRSFSLRWTTPAGDW FT DDSANERALAAFLGTFRDGAA" FT misc_feature complement(34539..35021) FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 30.80, E-value 1.9e-07" FT CDS complement(35454..36413) FT /transl_table=11 FT /gene="SCO7292" FT /gene_synonym="SC5F8.02c" FT /product="putative threonine dehydratase" FT /note="SC5F8.02c, possible threonine dehydratase, len: 319 FT aa. Similar to many including: Escherichia coli FT SW:THD2_ECOLI(EMBL:M21312) threonine dehydratase catabolic FT (EC 4.2.1.16) TdcB (329 aa), fasta scores opt: 609 FT z-score: 676.6 E(): 3.2e-30 39.4% identity in 312 aa FT overlap. Contains a Prosite hit to Serine/threonine FT dehydratases pyridoxal-phosphate attachment site and a Pfam FT match to entry PF00291 S_T_dehydratase, Pyridoxal-phosphate FT dependent enzyme." FT /db_xref="GOA:Q9K4M2" FT /db_xref="HSSP:1PWH" FT /db_xref="InterPro:IPR000634" FT /db_xref="UniProtKB/TrEMBL:Q9K4M2" FT /protein_id="CAB93730.1" FT /translation="MIAITEIEAAAERIAGHVVRTPTVPSPGLSALLGVPVTAKLELLQ FT RTGSFKARGATAKLLSLTEAERAAGVVAVSGGNHGIAVAVMAAALDVKATVVMPRTAPA FT RSVEIAEEAGALVRLTDGMDSAFALVTRLREEGLTLVHPFDDPVVVAGQGTVGLEFAED FT ASDLTDVLVSIGGGGLIAGVAAALRALRPGVRVWGVETEGAEAMSRALAAGGPLTVPLS FT SVVTTLSAPSVSRLTYDHVAELVTEVLVVPDREAVRGSLALAEHAKVWTEPAAGCLLPA FT ARRVVERVGDGARIGLVVCGGNATVGDMAVWADRFGLR" FT misc_feature complement(35508..36374) FT /note="Pfam match to entry PF00291 S_T_dehydratase, FT Pyridoxal-phosphate dependent enzyme, score 210.10, E-value FT 3.3e-59" FT misc_feature complement(36249..36290) FT /note="PS00165 Serine/threonine dehydratases FT pyridoxal-phosphate attachment site" FT CDS complement(36439..37116) FT /transl_table=11 FT /gene="SCO7293" FT /gene_synonym="SC5F8.03c" FT /product="conserved hypothetical protein" FT /note="SC5F8.03c, hypothetical protein, len: 225 aa. FT Similar to several proteins of undefined function FT including: Deinococcus radiodurans TR:Q9RWP1 FT (EMBL:AE001920) conserved hypothetical protein (254 aa), FT fasta scores opt: 467 z-score: 555.6 E(): 1.8e-23 36.6% FT identity in 205 aa overlap and Streptomyces coelicolor FT TR:CAB70638 (EMBL:AL137242) SC8F4.12C (239 aa), fasta FT scores opt: 397 z-score: 474.2 E(): 6.1e-19 36.1% identity FT in 183 aa overlap" FT /db_xref="InterPro:IPR000276" FT /db_xref="UniProtKB/TrEMBL:Q9K4M1" FT /protein_id="CAB93731.1" FT /translation="MKGDLFSSEHMVQPATAPGMTVENSKCIRYAVNGEMLARQGAMIA FT YRGNLQFERKGQGVGGMLKRAVTGEGLPLMAVRGQGEAWFANEAQNCFVVEVEPGDEFT FT VNGRNVLCFDASLSYRIATVKGSGIAGGGLFNSVFTGQGRLGLVCEGNPLVIPVSQQYP FT VHVDTDAVVGWSAGLATSLHRSQSIGSMLRGGSGEAVQLVLQGEGFVVVRPSEATPQKP FT QQH" FT CDS complement(37128..38432) FT /transl_table=11 FT /gene="SCO7294" FT /gene_synonym="SC5F8.04c" FT /product="conserved hypothetical protein" FT /note="SC5F8.04c, hypothetical protein, len: 434 aa. FT Similar to Streptomyces coelicolor TR:Q9X9W9 FT (EMBL:AL096743) putative transport associated protein, FT SCI7.21 (399 aa), fasta scores opt: 428 z-score: 449.2 E(): FT 1.5e-17 38.3% identity in 209 aa overlap" FT /db_xref="GOA:Q9K4M0" FT /db_xref="InterPro:IPR003325" FT /db_xref="UniProtKB/TrEMBL:Q9K4M0" FT /protein_id="CAB93732.1" FT /translation="MSDLVPGGNVPLPGGPVSVRVPGGFDVSALVTDEGGKVGGDADFV FT FYNQPEAPGARLRDDTLTVDPARLRRGAARVTVAVGPSDPGTPLGALPSPTVLVTDARG FT RTVARFTPARPGRETVLLLVEFYRRGEGWKVRALGQGYADGLAGLARDFGVEVTDDAPP FT EPATAPEPLTPGADSDGFLNLVNSARAAAGSPAVRPDPRLRSAARAHAAAMAAAGTLSI FT ETRDGVSVHQRVVSAGFAYLTVGEHLVSGPRTPAEFVAYCLRAERTRRTLHDTAFTHAG FT WACVTGGPSGDTYWTALWAVPLTPDGLARTTAEVVGLTNRERAGAGLPALAVDARLTAA FT AQAHSADMVTRDFYSHTDPDGGKPWDRAAAAGADRRSVGENIACGQRSPAEVVEGWMNS FT PGHRANILEAGFTHIGVGLAGGGRAGTYWTQLLGG" FT CDS complement(38524..41490) FT /transl_table=11 FT /gene="SCO7295" FT /gene_synonym="SC5F8.05c" FT /product="putative LuxR-family regulator." FT /note="SC5F8.05c, possible LuxR-family regulator, len: 988 FT aa. Similar to several other putative regulators from FT Streptomyces coelicolor including: TR:Q9XAN4 FT (EMBL:AL079355) SC4C6.06 (893 aa), fasta scores opt: 305 FT z-score: 328.7 E(): 7.7e-11 26.4% identity in 910 aa FT overlap and TR:Q9Z573 (EMBL:AL035569) SC8D9.18 (1091 aa), FT fasta scores opt: 857 z-score: 926.1 E(): 0 36.5% identity FT in 1077 aa overlap. Contains a Prosite hit to PS00017 FT ATP/GTP-binding site motif A (P-loop) Pfam match to entry FT PF00196 GerE, Bacterial regulatory proteins, luxR family." FT /db_xref="GOA:Q9K4L9" FT /db_xref="HSSP:1FSE" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9K4L9" FT /protein_id="CAB93733.1" FT /translation="MGGVPQTSLTSPLVGREDELARLTGVLERARAGEARAVLVAGDAG FT VGKTRTLHEAAGRAAAAGTTVLTGHCVDLGDVGLPYLPFTEILGVLAADERFAAVLAGH FT PVADRLLGGGPDDGTDAAPSRLRLFEGVAALLTELADVAPLLLVLEDLHWADQSSRDLL FT RFLLGRGVLQRPAGGAPGHRLALFASYRADDLHRRHPLRPLLAELVRLPGVERLELRPL FT PDSDVARLVRLLRERRLPDSTVRRIVERAEGNAFYAEELVAATDAPAGGVPSGLADVLL FT IRFEQLSETAQQVLRTAAVAGRRVGHDLLRDAVGLPEEELESALREAVERQLLVSGDGG FT AYSFRHALAREAVYADLLPGERARLHGAFARLLAGPDRRSDSAAERAHHYRESHDLPEA FT LAASLEAADHAQRVGAPAEELRHVEAALDLWTAVDAAARPAGPDAVTLTLRASAAAVHA FT GELHRAVSLTRSALAGLGQDADLELAARVRYTLAGNLLSVDNLESAYAYSSEALGLIPA FT EPPSSTWVWAAATHVTAARQVGENETALRVARRALRAAEELAVTDARADLLISLTSLEG FT GNRSTPEGRERLLEARELARRAGNAPVELRALFNLAIGCFESGDLEECLPWASEGLDRA FT RRSGLLSSPYPREMRYLRLLVQYTLGHWDEVLRESAEHAGERSAVDGHALGPGLYVALA FT RGDSGVADRARALLNGPFDWMARMVAGVVLTDAAALRGDAEDAVRWMRSSVETLTEAGT FT RPTVTLRLATLALSAVADTVTELRRAGDDAGVARWSDTAAELLADARWSAGHGYDDMPQ FT GPEGQAWLARAEAEWSRVAGAAPDPAAWERAVAAFTYGDTYERARCRLRLADALLAADR FT REEAATEAGGVRREADRLGATVLRERVDDLVRRGRLAGPARAGAGAAVLTAREQDVLRL FT LALGHSNRRIGEELFISAKTASVHVSNILAKLNAASRTEAVAVAHRQGLVAPEPTSSH" FT misc_feature complement(38545..38742) FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 93.60, E-value FT 4e-24" FT misc_feature complement(41344..41367) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(41557..41910) FT /transl_table=11 FT /gene="SCO7296" FT /gene_synonym="SC5F8.06c" FT /product="hypothetical protein SC5F8.06c." FT /note="SC5F8.06c, unknown, len: 117 aa. Similar in parts to FT Streptomyces coelicolor TR:Q9R3I9(EMBL:AJ249450) FT hypothetical 9.6 kd protein (86 aa), fasta scores opt: 295 FT z-score: 318.5 E(): 2.8e-10 51.4% identity in 72 aa FT overlap." FT /db_xref="GOA:Q9K4L8" FT /db_xref="InterPro:IPR001607" FT /db_xref="UniProtKB/TrEMBL:Q9K4L8" FT /protein_id="CAB93734.1" FT /translation="MTSDTGIDPTVPPSGTGCVECDAADGWWFHLRRCASCGHVGCCDS FT SPGQHATGHYRSTGHPVVQSFEPGEEWYWDYATSEVRESGPELAPPGSHPADQPSPGPA FT GRVPADWASTLHR" FT CDS complement(41907..43400) FT /transl_table=11 FT /gene="SCO7297" FT /gene_synonym="SC5F8.07c" FT /product="putative two-component sensor histidine kinase." FT /note="SC5F8.07c, possible two-component sensor histidine FT kinase, len: 492 aa. The C-terminus of this protein is FT similar to many sensor histidine protein kinases e.g. FT Salmonella typhimurium SW:NTRB_SALTY (EMBL:X85104) nitrogen FT regulation protein NR(II) (EC 2.7.3.-) (349 aa), fasta FT scores opt: 313 z-score: 363.5 E(): 8.9e-13 27.9% identity FT in 297 aa overlap. Contains a Pfam match to entry PF00512 FT signal, Histidine kinase. Also contains a 4xTPD repeat in FT the C-terminus." FT /db_xref="GOA:Q9K4L7" FT /db_xref="InterPro:IPR000595" FT /db_xref="UniProtKB/TrEMBL:Q9K4L7" FT /protein_id="CAB93735.1" FT /translation="MSGRPMPCSPEEIGKLFLFEKLTPEQLGRLCAEGRVELFDPGPVY FT AEGEDATCFYVMLAGTVVLSRRVGADDVETNRTSQPGVYAGAMQAYVGDRVPQVYNNSM FT RVTEPTRFFVLPADTFAAVMREWFPMAVHLLEGLFFGSKNTQRAIGQRERLLALGSLSA FT GLTHELNNPAAAAVRATSTLRERVAKMRHKLAVIAEGPFSREALAGLIEIQERTAERVA FT KAPSLSPLEAADREDDLGDWLEDHGIEHGWQLAPTFVQAGLDTEWLEQVAAAVDEEILP FT GAVGWLNYTVETELLMNEIADSTARISHLVDAAKQYAQLDRAPYRTVDVHELLDSTLLM FT LSGKIGPRIEVVKEYERTVPRVPAYPAELNQVWTNLIDNAVAAVNDAGGEGTLTVRTAL FT HHDRLLVEFRDTGTGIDPEIRERIFDPFFTTKPVGEGTGLGLDISWRIVVDKHHGSLQV FT ESVPGDTRFQVLLPLTAAEPDPADPTDPTDPTDPTEEPV" FT RBS complement(41916..41920) FT repeat_region complement(41922..41948) FT /note="repeat region containing 3xGATCCCACC translated in FT CDS SC5F8.07c." FT misc_feature complement(41985..42566) FT /note="Pfam match to entry PF00512 signal, Histidine FT kinase, score 103.20, E-value 5e-27" FT CDS complement(43397..45073) FT /transl_table=11 FT /gene="SCO7298" FT /gene_synonym="SC5F8.08c" FT /product="putative thioredoxin reductase." FT /note="SC5F8.08c, possible thioredoxin reductase, len: 558 FT aa. The C-terminus of this protein is highly similar to FT many thioredoxin reductases including: Streptomyces FT clavuligerus SW:TRXB_STRCL(EMBL:Z21946) thioredoxin FT reductase (EC 1.6.4.5) (321 aa), fasta scores opt: 494 FT z-score: 519.8 E(): 1.7e-21 32.8% identity in 332 aa FT overlap. The N-terminus is similar to the receiver domains FT of many response regulators e.g. Alcaligenes eutrophus FT SW:HOXA_ALCEU(EMBL:M64593) hydrogenase transcriptional FT regulatory protein, HoxA (482 aa) (32% identity over a 117 FT aa overlap). Contains Pfam matches to entries PF00070 FT pyr_redox, Pyridine nucleotide-disulphide oxidoreductase FT and PF00072 response_reg, Response regulator receiver FT domain." FT /db_xref="GOA:Q9K4L6" FT /db_xref="HSSP:1VDC" FT /db_xref="InterPro:IPR013027" FT /db_xref="UniProtKB/TrEMBL:Q9K4L6" FT /protein_id="CAB93736.1" FT /translation="MAQADGETRTVIMTVDDDPGVSRAVARDLRRRYGATYRIVRAESG FT ESALDALRELKLRGDLVAVILADYRMPQMNGIEFLEQALDVYPGARRVLLTAYADTNAA FT IDAINVVDLDHYLLKPWDPPEEKLYPVLDDLLQAWRAGDHRPVPSTKVVGHRWSARSSE FT VREFLARNQVPYRWYSSDEPEGRRLLSAAGQDGQRLPVVITPDGTPLVEPEAPELAARV FT GLATTPTSDFYDLVVIGGGPAGLGAAVYGASEGLRTVLVERSATGGQAGQSSRIENYLG FT FPDGVSGGQLTERARRQAARFGAEILTAREVTGLEANGAARVVRFSDGSAIAAHSVILA FT TGVSYRQLTAPGTEDLAGCGVFYGSALTEAASCQGHDVYIVGGANSAGQAAMYLARGAK FT SVTLLVRGGSLEASMSYYLIQQIEETPNIRVRCGTLVEGAHGDGHLERLTLRDAASGAT FT ELVDAQWLFVFIGAAPLTDWLDGTVLRDERGFILAGPDLTPDGRPPAGWELDRPPYHLE FT TSVPGVFVAGDARAESAKRVASAVGEGAMAVMLVHRYLEQS" FT RBS complement(43406..43409) FT misc_feature complement(43598..44371) FT /note="Pfam match to entry PF00070 pyr_redox, Pyridine FT nucleotide-disulphide oxidoreductase, score 89.90, E-value FT 8.8e-26" FT misc_feature complement(44684..45046) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 35.60, E-value 1.2e-06" FT CDS 45218..46156 FT /transl_table=11 FT /gene="SCO7299" FT /gene_synonym="SC5F8.09" FT /product="putative stress-inducible protein." FT /note="SC5F8.09, possible stress-inducible protein, len:312 FT aa. Highly similar to many proteins of undefined function FT e.g. Streptomyces coelicolor TR:Q9RIY4(EMBL:AL109962) FT hypothetical 34.7 kd protein, SCJ1.30C (328 aa), fasta FT scores opt: 604 z-score: 654.8 E(): 5.3e-29 41.8% identity FT in 328 aa overlap. Contains 2xPfam match to entry PF00582 FT Usp, Universal stress protein family." FT /db_xref="GOA:Q9K4L5" FT /db_xref="InterPro:IPR006015" FT /db_xref="UniProtKB/TrEMBL:Q9K4L5" FT /protein_id="CAB93737.1" FT /translation="MRTAWGRLGSENDVPATQGGTRMTRPITAGSDGSEESLAALVWAA FT REAVRRGAPLHVVHAWRFQGQGVAGAVDRETQEGWARDALARAVGTVAERHPGLTVTTD FT VREGDAVAALLAAAAGAETLVLGSRGHGAVVGFLLGSVGQQVIAEATRPVVLVRAGDEA FT TAEAGGREVVVGQQGEPEDSADVIGFAFEAAAARGATVRAVRAWALPTVFTYSPGSMAL FT ADEAGGLEQYERKALGEALAPWRERFPDVPVVEHVEMGSAGQVLLTVSADAQLMVVGRR FT ARRTAVGARIGSVAHGVLHHAECPVAVVPHR" FT misc_feature 45383..45688 FT /note="Pfam match to entry PF00582 Usp, Universal stress FT protein family, score 29.20, E-value 9.3e-05" FT misc_feature 45821..46144 FT /note="Pfam match to entry PF00582 Usp, Universal stress FT protein family, score 66.50, E-value 5.8e-16" FT CDS complement(46173..47405) FT /transl_table=11 FT /gene="SCO7300" FT /gene_synonym="SC5F8.10c" FT /product="hypothetical protein SC5F8.10c." FT /note="SC5F8.10c, unknown, len: 410 aa." FT /db_xref="UniProtKB/TrEMBL:Q9K4L4" FT /protein_id="CAB93738.1" FT /translation="MALQISATNPEHPALLLELPWQLPLEQWPEEYLVPLPRGISRHVV FT RYARAGDEVIAVKELAERPALREYQLLRDLDRLAIPAVDALAVVTGRLDAAGEALEPVL FT VTRHLGGSLPYRSMFETTLRPATMHRLMDALAVLLVRLHLAGFAWGDCSLSNTLFRRDA FT GAYAAYLVDAETGDLHPRLSDGQRDYDLDLARVNISGELLDLEASGALHPSVDPVEFGT FT EICARYRSLWQELTRTSVYPAGKYHYIERRIRRLNDLGFDVAEMQIEHASNGDTVSFVP FT KVVDAGHHQRQLLRLTGLDAEENQARRLLNDLESWMATQDDYAPGDPLGARPEVLAHRW FT VREVFRPTVRAVPVELRGAMDPAEIYHELLEHRWYLSERAQHDIGLDTAVEDYLVNILP FT RARETLQPTAD" FT CDS complement(47415..48161) FT /transl_table=11 FT /gene="SCO7301" FT /gene_synonym="SC5F8.11c" FT /product="conserved hypothetical protein SC5F8.11c." FT /note="SC5F8.11c, unknown, len: 248 aa. Highly similar to FT many beta-lactamase-like proteins including: Mycobacterium FT avium TR:Q9XC16(EMBL:AF152394) beta-lactamase-like protein, FT BllP (247 aa), fasta scores opt: 789 z-score: 885.8 E():0 FT 48.1% identity in 241 aa overlap. Contains a Pfam match to FT entry PF00753 lactamase_B, Metallo-beta-lactamase FT superfamily." FT /db_xref="GOA:Q9K4L3" FT /db_xref="InterPro:IPR001279" FT /db_xref="UniProtKB/TrEMBL:Q9K4L3" FT /protein_id="CAB93739.1" FT /translation="MSADVRQVADGTYLVHGGNTNWVILTDGDAVTLVDTGYPGDRRAL FT LDSLAAVGSSPEAVAAVLITHAHNDHLGSAEYLRTTHGTPVLLHEAEVPHARRDFLQQV FT SVGTVLRNAWRPGVLPWMRHVLRTGGTEQHPVTAPAAFPADGALDLPGRPVPVHTPGHT FT DGHCVYHLPDAGVVISGDALVSGHAISRIEGPQLLPDLFHHDRAGAVASLDVIAGLEGE FT VLLPGHGPVHRGPVKDAADLARERAF" FT misc_feature complement(47478..48119) FT /note="Pfam match to entry PF00753 lactamase_B, FT Metallo-beta-lactamase superfamily, score 96.00, E-value FT 7.6e-25" FT RBS complement(48165..48168) FT CDS complement(48240..48872) FT /transl_table=11 FT /gene="SCO7302" FT /gene_synonym="SC5F8.12c" FT /product="conserved hypothetical protein SC5F8.12c" FT /note="SC5F8.12c, hypothetical protein, len: 210 aa; FT similar to TR:AAK45279 (EMBL:AE006986) Mycobacterium FT tuberculosis CDC1551 hypothetical protein MT1029, 205 aa; FT fasta scores: opt: 784 Z-score: 926.8 E(): 5.5e-44; 56.796% FT identity in 206 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9K4L2" FT /protein_id="CAB93740.1" FT /translation="MTTHHLQGSLFDQTDEVRLGPLDGLRRTRLGPGAWIDLLPGWLSG FT ADALFERLAAEVPWRAERREMYERVVDVPRLLAFYGAGDALPHPLLAEARDALSAHYAE FT ELGEPFTTAGLCHYRDGRDSVAWHGDRIGRGARQDTMVAILSVGAPRDLLLRPAGGGGE FT TVRRPLGHGDLIVMGGSCQRTWEHCIPKSTRAAGPRISVQFRPHGVR" FT RBS complement(48885..48889) FT RBS 49057..49062 FT CDS 49066..49647 FT /transl_table=11 FT /gene="SCO7303" FT /gene_synonym="SC5F8.13" FT /product="putative TetR-family regulator." FT /note="SC5F8.13, possible TetR-family regulator, len: 193 FT aa. Weakly similar to Pseudomonas putida FT TR:O33453(EMBL:U24215) regulator of the p-cymene and FT p-Cumate catabolic operons, CymR (203 aa), fasta scores FT opt: 174 z-score: 221.1 E(): 7.6e-05 28.2% identity in 174 FT aa overlap. Contains a Pfam match to entry PF00440 tetR, FT Bacterial regulatory proteins, tetR family." FT /db_xref="GOA:Q9K4L1" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9K4L1" FT /protein_id="CAB93741.1" FT /translation="MHTRANLLDAAFAVFAAKGFGRVSIEEVCESAGYSRGAFYSNFDS FT LDELFFALYEQRADLIAEQVTTALAADGPGLDVPAAVERVTEVLLLDRDWLLVKTDFLV FT HAARDPAVARTLLEHRARLRRAIAGRLARARGHTALPAVLGDADEAAHAVVAAYDGVTT FT QLLLDRDVAGARVWLGQLLTALLTDGSTRH" FT misc_feature 49084..49224 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 55.10, E-value FT 1.1e-12" FT CDS 49687..51360 FT /transl_table=11 FT /gene="SCO7304" FT /gene_synonym="SC5F8.14" FT /product="conserved hypothetical protein SC5F8.14." FT /note="SC5F8.14, unknown, len: 557 aa. Highly similar to FT several proteins of undefined function including: FT Mycobacterium tuberculosis TR:P71838(EMBL:Z80226) (566 aa), FT fasta scores opt: 2386 z-score: 2598.2 E():0 63.1% identity FT in 553 aa overlap and Deinococcus radiodurans FT TR:Q9RYS0(EMBL:AE001863) (554 aa), fasta scores opt: 2249 FT z-score: 2449.3 E():0 60.2% identity in 555 aa overlap." FT /db_xref="GOA:Q9K4L0" FT /db_xref="HSSP:1D4D" FT /db_xref="InterPro:IPR003042" FT /db_xref="UniProtKB/TrEMBL:Q9K4L0" FT /protein_id="CAB93742.1" FT /translation="MDADVIVVGAGLAGLVAAHELTSRGRRVALVDQENAANLGGQAFW FT SFGGLFLVDSPEQRRLGVKDSLDLAWNDWQGSAGFDRTEDEDSWAVRWARAYVEWAAGE FT KRSWLAGHGITFLPTVGWAERGDLRAGGHGNSVPRFHIAWGTGTGVVEPFVRYAKQAAR FT DGLLTFHHRHRVDHLVVEDGTARGVRGTVLAPDDSPRGVASSRDTAGEFELAAQAVIVT FT SGGIGADHDIVRRHWPERLGTPPAEMVTGVPAYVDGRMLGISAEAGARLVNRDRMWHYT FT EGVRNWDPIWPGHGIRILPGPSSMWFDALGRRLPEPYLPGYDTLGTLRHLRTAEGLAEH FT GHSWFVLTRKIIEKEFALSGSEQNPDITAKDRAGFLRERVLGKGAPGPVGAFLRHGADF FT VTAPDLEQLVEKMNRLTDKPLLDAAALRRQIEARDLQLANPYAKDAQVQGIRNARRYIG FT DRLGRVATPHRLLDPAAGPLIGVKLHILTRKTLGGIQTDLDSRALGADGTPVEGLYAAG FT EVAGFGGGGVHGYNALEGTFLGGCLFSGRAAGRAAARQTA" FT CDS complement(51394..51747) FT /transl_table=11 FT /gene="SCO7305" FT /gene_synonym="SC5F8.15c" FT /product="conserved hypothetical protein SC5F8.15c." FT /note="SC5F8.15c, unknown, len: 117 aa. Highly similar to FT several proteins of undefined function including: FT Mycobacterium tuberculosis SW:YD08_MYCTU(EMBL:Z83866) (118 FT aa), fasta scores opt: 334 z-score: 429.2 E(): 1.9e-16 FT 49.1% identity in 112 aa overlap and Escherichia coli FT SW:YEAO_ECOLI(EMBL:AE000274) (122 aa), fasta scores opt: FT 296 z-score: 382.1 E(): 8.2e-14 42.7% identity in 110 aa FT overlap." FT /db_xref="InterPro:IPR007438" FT /db_xref="UniProtKB/TrEMBL:Q9K4K9" FT /protein_id="CAB93743.1" FT /translation="MNARVRRVYDPVEPDDGVRVLVDRLWPRGVSKDAARVDEWPKGLT FT PSAGLRRWYHAGEGSYEEFARRYEAELSAPEASELLDRVRELAEAGDVTLLTAARSPGE FT SHAAVLLRLLDEM" FT RBS complement(51754..51758) FT CDS complement(51809..52060) FT /transl_table=11 FT /gene="SCO7306" FT /gene_synonym="SC5F8.16c" FT /product="regulatory protein" FT /note="SC5F8.16c, regulatory protein, len: 83 aa. Highly FT similar to several e.g. Streptomyces coelicolor FT TR:CAB88918(EMBL:AL353862) regulatory protein, WhiB, FT essential for sporulation (87 aa), fasta scores opt: 214 FT z-score: 299.5 E(): 3.3e-09 45.1% identity in 71 aa FT overlap." FT /db_xref="InterPro:IPR003482" FT /db_xref="UniProtKB/TrEMBL:Q9K4K8" FT /protein_id="CAB93744.1" FT /translation="MDNWREHAACRTEDPDLFFPIGTTGPAALQTEQAKAVCRTCPVQE FT QCLRWALDTGQTLGVWGGTSELERRALKRREAARRRSG" FT RBS complement(52066..52071) FT CDS complement(52185..53087) FT /transl_table=11 FT /gene="SCO7307" FT /gene_synonym="SC5F8.17c" FT /product="putative LysR-family transcriptional regulator" FT /note="SC5F8.17c, possible LysR-family transcriptional FT regulator, len: 300 aa. Similar to many other LysR-family FT proteins including: Corynebacterium glutamicum FT SW:LYSG_CORGL (EMBL:X96471) lysine export transcriptional FT regulatory protein, LysG (290 aa), fasta scores opt: 780 FT z-score: 918.3 E():0 44.5% identity in 290 aa overlap and FT Escherichia coli SW:ICIA_ECOLI (EMBL:M62865) chromosome FT initiation inhibitor, IciA (297 aa), fasta scores opt: 538 FT z-score: 635.6 E(): 6.2e-28 37.1% identity in 291 aa FT overlap. Contains a Prosite hit to PS00044 Bacterial FT regulatory proteins, lysR family signature and a Pfam match FT to entry PF00126 HTH_1, Bacterial regulatory FT helix-turn-helix protein, lysR family with the putative FT helix-turn-helix motif situated between residues 23..44 FT (+4.82 SD)." FT /db_xref="GOA:Q9K4K7" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9K4K7" FT /protein_id="CAB93745.1" FT /translation="MTPTLADLPLDQVRTLLAVVDEGTFDAAAAALHVTPSAVSQRVKA FT LEQRTGRVLLLRTKPVRATDSGAVLVRLARQVARLERDASAELGLRGEGEPTRVTVAVN FT ADSLATWFLPALTRIPREPALCFELRREDEGHTATLLREGVVMAAVTSSPEPVPGCTVR FT TLGRMRYLPCAAPEFAARHLDAPLRETVAGAPVVVFDRRDDFQDSFARRLGHGGAGAAR FT HYVPTSEGFVEAVAAGLGWGMVPQPQAEPLLRTGRLVTFAPDLAVDVTLYWQQWKLDSP FT ALATVADAVVTAAADALRR" FT misc_feature complement(52641..53060) FT /note="Pfam match to entry PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix protein, lysR family, score FT 83.60, E-value 4e-21" FT misc_feature complement(52926..53018) FT /note="PS00044 Bacterial regulatory proteins, lysR family FT signature" FT CDS 53165..53779 FT /transl_table=11 FT /gene="SCO7308" FT /gene_synonym="SC5F8.18" FT /product="putative membrane transport protein." FT /note="SC5F8.18, possible membrane transport protein, len: FT 204 aa. Highly similar to many including: Corynebacterium FT glutamicum SW:LYSE_CORGL(EMBL:X96471) lysine exporter FT protein, LysE (236 aa), fasta scores opt: 201 z-score: FT 247.8 E(): 2.5e-06 34.8% identity in 224 aa overlap and to FT many hypothetical proteins e.g. Mycobacterium tuberculosis FT SW:YW33_MYCTU(EMBL:Z74025) (199 aa), fasta scores opt: 668 FT z-score: 801.1 E(): 0 54.0% identity in 200 aa overlap. FT Contains a Pfam match to entry PF01810 LysE, LysE type FT translocator and multiple possible membrane spanning FT hydrophobic domains." FT /db_xref="GOA:Q9K4K6" FT /db_xref="InterPro:IPR001123" FT /db_xref="UniProtKB/TrEMBL:Q9K4K6" FT /protein_id="CAB93746.1" FT /translation="MNNALTAAAAGFGTGLSLIVAIGAQNAFVLRQGVRRDAVLAVVGI FT CALSDAVLIALGVGGVGAVVVAWPGALTAVGWIGGAFLLCYGALAARRVFRPSGALRAD FT GAAAGSRRRAVLTCLALTWLNPHVYLDTVFLLGSVAADRGPLRWTFGLGAAAASLVWFA FT ALGFGARYLGRFLSRPVAWRVLDGLVAATMIVLGVSLVAGA" FT misc_feature 53369..53692 FT /note="Pfam match to entry PF01810 LysE, LysE type FT translocator, score 78.60, E-value 1.3e-19" FT CDS 53853..55187 FT /transl_table=11 FT /gene="SCO7309" FT /gene_synonym="SC5F8.19" FT /product="putative membrane transport protein." FT /note="SC5F8.19, possible membrane transport protein, len: FT 444 aa. Similar to many including: Streptococcus pyogenes FT TR:P95827(EMBL:U70055) macrolide-efflux protein, MefA (405 FT aa), fasta scores opt: 339 z-score: 368.8 E(): 4.5e-13 FT 23.1% identity in 399 aa overlap and Streptomyces FT coelicolor TR:Q9RKR4(EMBL:AL133220) putative integral FT membrane protein, SCC75A.10 (431 aa), fasta scores opt: 895 FT z-score: 962.2 E(): 0 38.2% identity in 408 aa overlap. FT Contains multiple possible membrane spanning hydrophobic FT domains." FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9K4K5" FT /protein_id="CAB93747.1" FT /translation="MYRACRKRVDTSESSSQSGTGPDAKAAAPDGTRQRGWRRWAMDTR FT PLRRPAYRRLWSSTVVTAVGSQLTAVAVPKQIYDITGSSAWVGAASLAGLLPLIVFALW FT GGAVADTVDRRKLLLITNTGIAVTSLLFWIQAVTGMASVAALMLLLALQQAFWGLNAPA FT RNASIARLVPEDELPAANALGSTVMQTGQVVGPLLAGALIPVIGLPELYLIDALALCVT FT VWAVYKLPALPPLAGTAVRRAGVREVVAGFRYIARHKVLLLSFLADIVAMVFGMPRALF FT PQLAAETYAPYGEGLALGLLFAAIPIGAVAGGLFSGTFSRARRHGWMVIGAVVVWGAAI FT TGFGLSGSLWLAVAFLVVAGVADMVSMVFRGAILLSAATDEMRGRMQGVFTVVVAGGPR FT LADVLHGGAGSAAGAREAVAGGGLLVVAVMLALAVAMPALRRYRV" FT CDS complement(55195..55650) FT /transl_table=11 FT /gene="SCO7310" FT /gene_synonym="SC5F8.20c" FT /product="putative regulatory protein." FT /note="SC5F8.20c, possible regulatory protein, len: 151 aa. FT Similar in parts to Pseudomonas sp.TR:O52578 FT (EMBL:AF040987) putative FNR-like regulator, NnrR (223 aa), FT fasta scores opt: 161 z-score: 223.3 E(): 5.7e-05 25.2% FT identity in 131 aa overlap and Streptomyces coelicolor FT TR:Q9RIZ7 (EMBL:AL109962) possible regulator protein, FT SCJ1.17 (190 aa), fasta scores opt: 500 z-score: 675.2 E(): FT 3.8e-30 49.7% identity in 151 aa overlap. Contains a Pfam FT match to entry PF00027 cNMP_binding, Cyclic FT nucleotide-binding domain." FT /db_xref="InterPro:IPR014710" FT /db_xref="UniProtKB/TrEMBL:Q9K4K4" FT /protein_id="CAB93748.1" FT /translation="MTKAIKLLNALPLPQRARLMELAQEVSFPEDDRIFEAGGRADRFW FT VIRSGAVSLTQQVTSLQRVTVASLGVGDLLGWSWLFPPYEWDFGAEAFSPVRAYEFEAA FT SVLDLCERDPQLGIVLVRSVAEILAHRLESTRGRLMEHYALHGRGSL" FT misc_feature complement(55306..55587) FT /note="Pfam match to entry PF00027 cNMP_binding, Cyclic FT nucleotide-binding domain, score 38.00, E-value 2.2e-07" FT CDS complement(56005..57483) FT /transl_table=11 FT /gene="SCO7311" FT /gene_synonym="SC5F8.21c" FT /product="probable amino acid decarboxylase" FT /note="SC5F8.21c, probable amino acid decarboxylase, len: FT 492 aa. Similar to many e.g. Bacillus subtilis FT SW:DCLY_BACSU (EMBL:X58433) lysine decarboxylase (EC FT 4.1.1.18) (490 aa), fasta scores: opt: 1108 z-score: 1197.8 FT E():0 35.6% identity in 494 aa overlap. Contains a Pfam FT match to entry PF01276 OKR_DC_1, Orn/Lys/Arg FT decarboxylase." FT /db_xref="GOA:Q9K4K3" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:Q9K4K3" FT /protein_id="CAB93749.1" FT /translation="MTVDHRRAPVLEALVEYRRAGRLSFTPPGHKQARGADPAVREVLG FT DAVFHGDVLATAGLDDRLTRGRVLQRAQELMADAVHADHTFFTTCGSSLSVKAAMLAVA FT GPHEKLLIGRDAHKSVVSGLILSGIEPVWVEPRWDAERHLAHPPSAESFEEAFGAHPDA FT KGALITSPTPYGASADLRAVAEVCHGRSLPLIVDEAWGAHLPFHPDLPSWAMDAGADIC FT VTSIHKMGSGLEQGSVFHLRGDLVPPKLLGMRADLLSTTSPSVLIFAGLDGWRRQMALG FT GQELMGGALELAAGVRAAVEEIDGMHVNDREDFCGPGLAHGFDPLPVVIDLEGLGVSGF FT RAADWLREHRGVVAHLTDHRRIGAQITHGDDRGTAGELLTALKDLALAAPGLGSAPGVE FT VPSPAELRMPQVCLPRDAFFGPTEDVPLDRAAGRVAAEMITPYPPGIPAVLPGERLAEP FT VLRYLRSGLEAGMYLPDPTDPALETVRVVAEHGA" FT misc_feature complement(56008..57468) FT /note="Pfam match to entry PF01276 OKR_DC_1, Orn/Lys/Arg FT decarboxylase, score 205.40, E-value 8.5e-58" FT CDS complement(57513..57746) FT /transl_table=11 FT /gene="SCO7312" FT /gene_synonym="SC5F8.22c" FT /product="hypothetical protein" FT /note="SC5F8.22c, unknown, len: 77 aa." FT /db_xref="UniProtKB/TrEMBL:Q9K4K2" FT /protein_id="CAB93750.1" FT /translation="MTDVVDADELLRRMHRARACALEEGRSWRARSEALRSTDPEGARE FT AAVRTVAYEAVLRVLDEVLTPGRNADRRSPAD" FT RBS complement(57750..57753) FT RBS 57891..57894 FT CDS 57902..58348 FT /transl_table=11 FT /gene="SCO7313" FT /gene_synonym="SC5F8.23" FT /product="hypothetical protein SC5F8.23." FT /note="SC5F8.23, unknown, len: 148 aa. Weakly similar to FT several putative regulatory proteins e.g. Streptomyces FT coelicolor A3(2) TR:Q9RIS7(EMBL:AJ249581) putative FT regulator of sig15 (170 aa), fasta scores opt: 144 z-score: FT 184.4 E(): 0.0084 36.1% identity in 133 aa overlap and FT Streptomyces coelicolor TR:Q9RD41(EMBL:AL133422) SCM1.01C FT (147 aa), fasta scores opt: 225 z-score: 281.4 E(): 3.3e-08 FT 36.6% identity in 131 aa overlap." FT /db_xref="GOA:Q9K4K1" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9K4K1" FT /protein_id="CAB93751.1" FT /translation="MRDRDTIQPVVEQRGGDTGRRYRPCRPADARAAVERAVTECRGAG FT GRASCDPCALSDAVLVASELTTNAILHGGGITDFQVDVVGPGVRLSVCDRSHDLPVAVP FT ATDDRGRRRLGGRGWPIVCRLAREVRVADLPSGGKCITVVVPLS" FT CDS 58541..59440 FT /transl_table=11 FT /gene="SCO7314" FT /gene_synonym="SC5F8.24" FT /product="probable RNA polymerase sigma factor" FT /note="SC5F8.24, probable RNA polymerase sigma factor, len: FT 299 aa. Highly similar to many e.g. Streptomyces coelicolor FT SW:RPOF_STRCO (EMBL:L11648) RNA polymerase sigma-F factor, FT SigF (287 aa), fasta scores opt: 687 z-score: 772.9 E(): 0 FT 43.6% identity in 275 aa overlap. Contains a Pfam match to FT entry PF00140 sigma70, Sigma-70 factor and a putative FT helix-turn-helix motif situated between residues 242..263 FT (+6.95 SD)." FT /db_xref="GOA:Q9K4K0" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9K4K0" FT /protein_id="CAB93752.1" FT /translation="MLIETPTIRPGTTQSAHPSTAPARRRHDDAPDTMVLFGRLAGLAD FT GPERDAVRDELVTAWLPMAHRIAGRFRDRGESIEDLRQVAALGLVKAIDRFDPERGAFE FT SYAVPTITGEVKRHFRDRMWALRVPRRVQELRNKVRVARRELAQSPGSPEPSVAALAAH FT TGLSEDEVGAGMEALESFSTLSLDAELSAGDDGYSLADTLGAADTSYDTVIDRESAKEG FT LRRLPERERAILYMRFFEDMTQSRIADCLGISQMHVSRLISRSCARVRDEAMGQRTARS FT GTRRGPDGGHKDHRGHSR" FT misc_feature 58688..59353 FT /note="Pfam match to entry PF00140 sigma70, Sigma-70 FT factor, score 189.70, E-value 4.7e-53" FT CDS 59460..59699 FT /transl_table=11 FT /gene="SCO7315" FT /gene_synonym="SC5F8.25" FT /product="hypothetical protein SC5F8.25." FT /note="SC5F8.25, unknown, len: 79 aa. Similar to FT Streptomyces coelicolor TR:O54206(EMBL:AJ001206) FT hypothetical protein, PepA (90 aa), fasta scores opt: 106 FT z-score: 152.7 E():0.49 32.2% identity in 87 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9K4J9" FT /protein_id="CAB93753.1" FT /translation="MLMPHPAVLRRLLAEYEAAAVNEPADATGEPGPRTRDLAYTLCVS FT TGTRDVRRALETARRHLAAAPEPVAGAAHAAVAD" FT RBS 59748..59752 FT CDS 59760..60602 FT /transl_table=11 FT /gene="SCO7316" FT /gene_synonym="SC5F8.26" FT /product="putative integral membrane protein" FT /note="SC5F8.26, possible integral membrane protein, len: FT 280 aa. Similar to Bacillus subtilis FT SW:YXXB_BACSU(EMBL:D45912) hypothetical 31.8 kd protein FT (289 aa), fasta scores opt: 476 z-score: 539.7 E(): 1.4e-22 FT 31.0% identity in 245 aa overlap. Contains multiple FT possible membrane spanning hydrophobic domains" FT /db_xref="InterPro:IPR009597" FT /db_xref="UniProtKB/TrEMBL:Q9K4J8" FT /protein_id="CAB93754.1" FT /translation="MNAGVAGGLARTGRGRARRAANGSAAEGAARAGLAARGVIYLLVG FT ILALQIAFGGGNRQADRGGALAELSDRPFGAVLLWALGAGLVGMALWRLSEAAFGVTGK FT DGHKAKKRLPAAARCVFYAFVAYSVLAFAAGSGGGGSSDRQSRDVTARVMEMPAGRWLV FT GAAGVAIVVAGVVIGVQALRRTYRKKMKLGGLSPRTRLLVDVTGVGGGTARGIVFAAAG FT AFAVRAALAYEPDRAKGLDDTLRSFARTPLGPWLLALVAAGLVLFGVFSFVLARLRRV" FT CDS 60631..61065 FT /transl_table=11 FT /gene="SCO7317" FT /gene_synonym="SC5F8.27" FT /product="hypothetical protein SC5F8.27." FT /note="SC5F8.27, unknown, len: 144 aa." FT /db_xref="UniProtKB/TrEMBL:Q9K4J7" FT /protein_id="CAB93755.1" FT /translation="MNEHEIPPPDGRPVDVYLDLLRVRMASDDYQLLLSVVEPVLQAID FT EQQMPTIDFSLDGDSAEALPQEIRDEAALVIATAVTGRLDNEVVEISTDETGPVRVVTD FT ATTASDPERLGEIADYLKERHQQNEELRGIAEASGLPSDF" FT CDS complement(61089..63347) FT /transl_table=11 FT /gene="SCO7318" FT /gene_synonym="SC5F8.28c" FT /product="putative membrane protein" FT /note="SC5F8.28c, possible membrane protein, len: 752 aa; FT similar to TR:Q9AJZ2 (EMBL:AL512944) Streptomyces FT coelicolor putative integral membrane protein SC8D11.27c, FT 753 aa; fasta scores: opt: 773 Z-score: 794.0 E(): 1.4e-36; FT 37.281% identity in 743 aa overlap. Contains multiple FT possible membrane spanning hydrophobic domains. Note the FT predicted product of this CDS is rich in the amino acid FT Leucine" FT /db_xref="UniProtKB/TrEMBL:Q9K4J6" FT /protein_id="CAB93756.1" FT /translation="MYGGVKAAGRSARTRLRDRVAASDPGLLRLTAGLRTVGAIALTLG FT VLAVFGVDVKHLVAGAMAAMVATFAIREKEPGPQAVTLALGLPVALASVSLSTLLASWV FT VVGDAFFVVLIFSAVFVRRFGDRGTALGLIGFQVYFVSLFVGGKVSGLPGLWAAVAVAF FT ASSAVVRFGVVPATPARILGLLRQAFRARLAQLIATQIELLDAGPDDIDKTLERLREGT FT ARLHETALLIQSRLDEGTPDASTARLVQRRIADAEIAAERLGLLLLTARSAERADTLTL FT HLPGAPAPAVGHSPAPGEATELLRRDLTALRTLVLRPPAEARGTALSHLRNRLLGYRDE FT ENLPEATAAVQDVFRGVGETARAVMGLRIALDGPQDESDDSPATARSREELDAEDAAID FT AGEEAAQKEEPTGLRRPTTRAAVQVAVGSSLAIVGGEFLSSQRWYWAVLTCWIVFINTA FT STGEILVKGYRRLLGTVLGVVAGIVLAGLVGNHTWTAFGLVLVLIFAMFYTAPLSYTLM FT SFFVTAMLGLLYTLLHTYSMSVLLLRVEETALGAACGIVAAALVLPIRTDRRTNDLLGT FT VLERLSDVTEGAVDQLSGGPEADLLDTARELDQALGDLRAATQPLTHPITPLRARRDTA FT QYVVALLETCAYHARSLAATAELLPTHPSIAADPRLRGAVRRTVRNIEAIAAHVADENA FT GTQVETGPSIASLLEPDAAGVPRYGRITGRVLRHLERLDEAVVGLARPLGVSVGAPQR" FT CDS complement(63470..64915) FT /transl_table=11 FT /gene="SCO7319" FT /gene_synonym="SC5F8.29c" FT /product="putative oxidoreductase." FT /note="SC5F8.29c, possible oxidoreductase, len: 481 aa. FT Similar to many dehydrogenases including: Escherichia coli FT SW:DHNA_ECOLI(EMBL:V00306) NADH dehydrogenase (EC 1.6.99.3) FT (433 aa), fasta scores opt: 438 z-score: 509.8 E(): FT 6.4e-21 26.3% identity in 384 aa overlap and Streptomyces FT coelicolor TR:Q9ZC17(EMBL:AL033505) putative dehydrogenase, FT SC1E6.05 (629 aa), fasta scores opt: 1148 z-score: 1329.8 FT E(): 0 44.3% identity in 420 aa overlap. Contains a Pfam FT match to entry PF00070 pyr_redox, Pyridine FT nucleotide-disulphide oxidoreductase. Note codon 27 may FT offer an alternative translational start site." FT /db_xref="GOA:Q9K4J5" FT /db_xref="InterPro:IPR013027" FT /db_xref="UniProtKB/TrEMBL:Q9K4J5" FT /protein_id="CAB93757.1" FT /translation="MRSGDPRAGEWRSRQTAPEPQKGMNTVTRPRILVVGAGFAGVECV FT RRLERRLSPDEADVTLVTPFSYQLYLPLLPHVAAGVLTPQSIALSLRRSSRYRTRIIPG FT GAIGVDLEAKVCVVRTITDRIVNEPYDYIVLAPGSITRTFDIPGLTDNAFGMKTLAEAA FT YIRDHVISQLDLADASQDPVERASRLQFVVVGGGYAGTETAACLQRLTHAAVKRYNRLD FT PALIKWHLIDIAPKLMPELGEKLGRDAQQILTRRGIDISLGVSIAKAAPEEVTFTDGRV FT VPTRTLIWTAGVVASPLMATLGAETVKGRLAVTAEMCLPNHDGVFALGDSAAVPDLAKG FT QEGAVCPPTAQHAQRQGRHVAENLIATLRNQPMRPYVHKDLGLVVDLGGADAVSKPLGV FT ELTGLPAQAVARGYHWSALRTGVAKARVAANWALNAVAGDDFVRTGFQARKPAKLKDFE FT YTDAYLTPEQVRERVAEADRAKP" FT misc_feature complement(63923..64822) FT /note="Pfam match to entry PF00070 pyr_redox, Pyridine FT nucleotide-disulphide oxidoreductase, score 79.20, E-value FT 1.3e-22" FT CDS complement(65055..66797) FT /transl_table=11 FT /gene="SCO7320" FT /gene_synonym="SC5F8.30c" FT /product="conserved hypothetical protein SC5F8.30c" FT /note="SC5F8.30c, unknown, len: 580 aa. Similar in parts to FT many Streptomyces coelicolor proteins of undefined function FT including: TR:Q9RJE1(EMBL:AL133171) putative regulatory FT protein, SCF81.10C (828 aa), fasta scores opt: 676 z-score: FT 710.0 E(): 4.5e-32 34.7% identity in 426 aa overlap and FT TR:Q9X8W1(EMBL:AL078610;) hypothetical 66.2 kd protein, FT SCH35.45C (634 aa), fasta scores opt: 633 z-score: 666.6 FT E(): 1.2e-29 33.4% identity in 539 aa overlap." FT /db_xref="GOA:Q9K4J4" FT /db_xref="InterPro:IPR010822" FT /db_xref="UniProtKB/TrEMBL:Q9K4J4" FT /protein_id="CAB93758.1" FT /translation="MTRTWQISDVTDAAVARVAAARLATAFGVPPVERARLTASLGAQL FT RLCLTKGGTWRLALETGTVSRPAPQAAERVLHAVVTPSPEAAAAGQPPWRVTVPCPEAD FT DVGAIADAGAVADDPVELAQALLGADEDTALVLERLTEQEGLVDFHREELQQTNQGVVA FT LHAELDAAGRAQREAFAAERKARTEAEHARRRLTFLADASAVLTASLDHHEIVRRLPEL FT LVPEYATGVDIWLFDQDGDRPGPAHAAAAVVAARTGRPQYAAAHPGGLPGVDDQPPSAL FT APDRPLLCIPLPTRQAPLGVVTLSPPGDRWDPDDAVMLVELTRRASIAIDHAQRYQHNR FT DIAETLQRALLTELPAPPGLALAARYLPATHGLNIGGDWYDAFRQPDGGVIAVVGDVTG FT HGLRAAVMMSQLRTALRAYAVDGGSPGQLLTRLHTFLHHLQPDLFATAVIARFHPDDPT FT VTWAAAGHPPPVLRTPDGGVRTLDAKPGAMLGIPMRQEIADHTVPMAPGSTLALYTDGL FT VERRARGIDPGIARLADALASFGPAELDTDLEGSADGILRPMLSDSERDDDVCLLLCHL FT RGTG" FT CDS complement(66794..67858) FT /transl_table=11 FT /gene="SCO7321" FT /gene_synonym="SC5F8.31c" FT /product="conserved hypothetical protein SC5F8.31c." FT /note="SC5F8.31c, unknown, len: 354 aa. Similar to FT Deinococcus radiodurans TR:Q9RZT6(EMBL:AE001826) FT hypothetical TorS-related protein (351 aa), fasta scores FT opt: 393 z-score: 443.7 E(): 3e-17 34.7% identity in 354 FT aa overlap." FT /db_xref="GOA:Q9K4J3" FT /db_xref="InterPro:IPR010822" FT /db_xref="UniProtKB/TrEMBL:Q9K4J3" FT /protein_id="CAB93759.1" FT /translation="MPRVWDVPVHDSTRVRDARVAAEHAAAVAGLDEQRTSAAALVATE FT LATNLLKHAGGGRVVVDVVAPPVLAADREPRPRVQIATVDHGPGMADVSAALRDGFTTT FT TGSLGAGLGTCARVADDFDLHSAPGRGTVVVARIGVPEARAADSGPAARLRAGAVNVPF FT GGAEYSGDAWAWVRDRDLVTLMLADGLGHGPEAARASTAAVEALRASAHLAPGEAVRRL FT DRALSGTRGAAVAVAQVDTRASVLRFAGVGNIGARLCEGGTWRHLVSRPGIVGTHRPTT FT LREEQAAWADDRVLVLHSDGLPSRWSPTSDTCRTTTDPAVTAAVTIRDASSSARPVRDD FT TAVAVLAPTPPDGP" FT CDS complement(67858..68298) FT /transl_table=11 FT /gene="SCO7322" FT /gene_synonym="SC4G10.01c" FT /gene_synonym="SC5F8.32c" FT /product="putative anti-sigma factor" FT /note="SC4G10.01c, possible anti-sigma factor, partial CDS, FT len: >57 aa. Highly similar to several including: Bacillus FT subtilis SW:RSBT_BACSU (EMBL:L35574) anti-sigma B factor FT controlling SigB the general stress sigma factor (133 aa), FT fasta scores opt: 144 z-score: 235.0 E(): 1.3e-05 48.0% FT identity in 50 aa overlap and Deinococcus radiodurans FT TR:AAF12580(EMBL:AE001826) sigma-B regulator, RsbT (137 FT aa), fasta scores opt: 201 z-score: 321.3 E(): 2e-10 63.2% FT identity in 57 aa overlap." FT /note="SC5F8.32c, possible anti-sigma factor, partial CDS, FT len: >129 aa. Highly similar to several anti-sigma factors FT including: Bacillus subtilis SW:RSBT_BACSU(EMBL:) FT anti-sigma B factor, RsbT (133 aa), fasta scores opt: 452 FT z-score: 536.7 E(): 2e-22 57.6% identity in 118 aa overlap. FT Overlaps and extends into CDS SC4G10.01c on the adjoining FT cosmid." FT /db_xref="GOA:Q8CJK4" FT /db_xref="HSSP:1L0O" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q8CJK4" FT /protein_id="CAD55396.1" FT /translation="MHTAAGSQARLPIRSDMDLVWVRQHVRQAAAQLGFGLVDQTKLVT FT AASELARNTLVYGGGGTMETESILEGTTHGLRLTFSDEGPGIPDVEQALSDGFTSGDGL FT GMGLGGARRLVHEFAIESAPGSGTTVRVTSWVGRPPRPREES" FT RBS complement(67864..67868) FT CDS complement(68298..68729) FT /transl_table=11 FT /gene="SCO7323" FT /gene_synonym="SC4G10.02c" FT /product="anti-sigma factor antagonist" FT /note="SC4G10.02c, anti-sigma factor antagonist, len: 143 FT aa. Highly similar to many anti-anti sigma factors e.g. FT Bacillus subtilis SW:RSBS_BACSU (EMBL:L35574) anti-sigma FT factor antagonist, RsbS (121 aa), fasta scores opt: 341 FT z-score: 417.5 E(): 8.5e-16 43.4% identity in 113 aa FT overlap. Contains a Pfam match to entry PF01740 SpoIIAA, FT SpoIIAA family." FT /db_xref="InterPro:IPR002645" FT /db_xref="UniProtKB/TrEMBL:Q9KY15" FT /protein_id="CAB92869.1" FT /translation="MSQAFPGPHGAPATGHVPVLRLGEVLLVTLQGDLHDSTAQQLQED FT LAETIVRSGATGVVIDVSGVEIVDSFLGRILAEIAGQTGLLAARTVLVGMRPAVAITLV FT ELGLTLPGVHTALSTEVAMELLRQQAPSSRFGGLRQESQ" FT RBS complement(68307..68311) FT misc_feature complement(68364..68684) FT /note="Pfam match to entry PF01740 SpoIIAA, SpoIIAA family, FT score 18.60, E-value 0.00021" FT CDS complement(68726..69625) FT /transl_table=11 FT /gene="SCO7324" FT /gene_synonym="SC4G10.03c" FT /product="putative regulatory protein" FT /note="SC4G10.03c, possible regulatory protein, len: 299 FT aa. Similar to Bacillus subtilis SW:RSBR_BACSU(EMBL:L35574) FT positive regulator of sigma-B activity, RsbR (274 aa), FT fasta scores opt: 401 z-score: 450.7 E(): 1.2e-17 27.6% FT identity in 279 aa overlap." FT /db_xref="InterPro:IPR002645" FT /db_xref="UniProtKB/TrEMBL:Q9KY14" FT /protein_id="CAB92870.1" FT /translation="MPEQAEGTAGAPTREVRDFLRRHREQIAQRWADEPLFRAVFTVSR FT DEAVEAAKAVVDALDQVADAARVEDPDAAGFTAVREQLARMGAARSRAGLSTAQVSSEL FT AALRPPVENLLVAALPDQAPAEHVRDCVTALNVLMGTLRVVVMQTALSEGQALIDRQRL FT QLLEVATPVIKLWDGIVAVPLIGTLDSARSQVVMETLLESIVEQQARYAILDITGVPTV FT DSLVAQHLMKTVAAARLMGAECIVSGIRPAIAQTMVHLGLDLGTVVTRASLADALGYVL FT HQLGVGIVTPHANGAVAR" FT RBS complement(69634..69638) FT CDS complement(69786..70178) FT /transl_table=11 FT /gene="SCO7325" FT /gene_synonym="SC4G10.04c" FT /product="anti-sigma factor antagonist." FT /note="SC4G10.04c, anti-sigma factor antagonist, len: 130 FT aa. Similar to many including: Bacillus licheniformis FT SW:SP21_BACLI (EMBL:M25260) anti-sigma F factor antagonist FT (stage II sporulation protein AA) (117 aa), fasta scores FT opt: 187 z-score: 252.1 E(): 1.4e-06 28.4% identity in 109 FT aa overlap and Streptomyces coelicolor SW:RSBV_STRCO FT (EMBL:AF134889) anti-sigma factor antagonist, BldG (113 FT aa), fasta scores opt: 196 z-score: 263.7 E(): 3.2e-07 FT 26.5% identity in 102 aa overlap. Contains a Pfam match to FT entry PF01740 SpoIIAA, SpoIIAA family." FT /db_xref="GOA:Q9KY13" FT /db_xref="InterPro:IPR003658" FT /db_xref="UniProtKB/TrEMBL:Q9KY13" FT /protein_id="CAB92871.1" FT /translation="MPIAQNPLSVEVTLPREDVALLKVEGYLDVDTATEFQHHLANQLH FT HGRRHFLLDLSAVPFMDSSGMNIILRVYQEARELPGSVHIISPVPAVLRVLDLTGVSIT FT VPVSANLDEALARVDAQPEGPRVPDA" FT misc_feature complement(69837..70154) FT /note="Pfam match to entry PF01740 SpoIIAA, SpoIIAA family, FT score 72.50, E-value 8.6e-18" FT CDS complement(70296..72770) FT /transl_table=11 FT /gene="SCO7326" FT /gene_synonym="SC4G10.05c" FT /product="conserved hypothetical protein" FT /note="SC4G10.05c, unknown, len: 824 aa. Similar to several FT Streptomyces coelicolor proteins of undefined function e.g. FT TR:CAB61192(EMBL:AL132973) SCF91.35 (884 aa), fasta scores FT opt: 385 z-score: 407.5 E(): 3.1e-15 26.1% identity in 885 FT aa overlap" FT /db_xref="GOA:Q9KY12" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9KY12" FT /protein_id="CAB92872.1" FT /translation="MSTPEQPGDPAGALRRDVSDPVDLTPLSPVGRLAATVDRLSREVR FT AAQAEAEGRALIELAKGVLVARLGCGPAEAARQLAELAEQSRATPLEFAVDVINQAARD FT RMSEVTEAFLAATAAVRATVPADGARGTERGDSTTGTQGAQAVAESAAVRLRAAESGAL FT AADDTQAVADALLEQALRPLGAVAVAIWSAGYDGSLTLVGSAGFPPAEAARWRYVPPDV FT ATAARRGLTERSGQWFASLAGTGLPSVGRHQYPEGGRVAVPAGTGGRIHGVLEIVWPVP FT LAPQPPQVVRQVEALAELCAHTLESYTPPREPGQEPRVIPDAVELMDLADGLHDPALVL FT VPHLDAAGQLADFRIQHVNKRFMDPAGRPRAVVGGALLLEAYPMAAGDSELFQNVERVY FT ATGEPFRARHLNLTALVDQVPLAAVADISISRHGNAVLLIWRIEDETARLASLLQHAQR FT LGRIGGFEENLLTGEITWNGQLFDLYGRPHTSTPVPLEELAAHAHPDDAVAIGRFLRTL FT LHHRRPASAAFRLRRPDGVTRHVRVVAEPVLDTDDRLLLVRGACQDISAQHWTEVALAA FT TRDQLAHTEQQAVERARLTLQLQHAIMPPAQTPLRVPDLQVAVRYRPAETEQLVGGDWY FT DAVMLPSGLVLLCVGDVAGHGIEAATSMVVLRNALRGLAVTGAGPGQLLSWLNIVAHHL FT TGGVTATAVCGLYDPARRTLRWARAGHLPPVLVRGPEAEPLPLVRGMLLGAVAEAAYEE FT AEAELAAGDTLLMYTDGLIERRDRPVEEALAQLLSTVRPTPNTLDQHLDRLLTYSRSDT FT DDDTCLVGIRVG" FT CDS complement(72767..76762) FT /transl_table=11 FT /gene="SCO7327" FT /gene_synonym="SC4G10.06c" FT /product="putative two-component system sensory histidine FT kinase." FT /note="SC4G10.06c, possible two-component system sensory FT histidine kinase, len: 1331 aa. Highly similar in parts to FT many including: Pseudomonas syringae (pv. syringae) FT SW:LEMA_PSESY(EMBL:M80477) sensor protein, LemA (EC FT 2.7.3.-), (907 aa), fasta scores opt: 641 z-score: 627.6 FT E(): 1.7e-27 31.2% identity in 872 aa overlap and FT Streptomyces coelicolor TR:O86808(EMBL:AL031031) putative FT sensory histidine kinase, SC7C7.03 (1829 aa), fasta scores FT opt: 2600 z-score: 2540.8 E():0 59.1% identity in 1346 aa FT overlap. Contains Pfam matches to entries PF00072 FT response_reg, Response regulator receiver domain, PF00512 FT signal, Histidine kinase and Pfam match to entry PF01590 FT GAF, GAF domain. Contains a 5x degenerate repeat region FT between residues 55..493 and a possible coiled-coil between FT residues 701..756." FT /db_xref="GOA:Q9KY11" FT /db_xref="HSSP:1NTR" FT /db_xref="InterPro:IPR003660" FT /db_xref="UniProtKB/TrEMBL:Q9KY11" FT /protein_id="CAB92873.1" FT /translation="MTSDSAGPVDAVPGDQELRRLLAGLTAVRDGDFGTRLPDDADGLM FT GDIAKVFNGMVDQLSVFTSEVTRVSREVGTEGALGGQARVPGVSGTWADLTDSVNAMAG FT NLTSQVRDIAQVATAVARGDLSQKIDVDARGEILELKNTINTMVDQLSAFADEVTRVAR FT EVGTDGRLGGQADVQGVRGTWRDLTDSVNFMAGNLTNQVRNVAQVATAVAKGDLSQKIT FT VDARGEILELKNTINTMVDQLSAFADEVTRVAREVGTAGNLGGQARVRGVSGTWKDLTD FT NVNVMASNLTGQVRSIAQVATAVARGDLSQRITVDAEGEVAALADVINTMVDTLSAFAD FT EVTRVAREVGTDGRLGGQANVPNVAGTWKDLTDNVNSMANNLTNQVRNIALVTTAVARG FT DLSKKIDVDARGEILELKTTINTMVDQLSAFADEVTRVAREVGTEGRLGGQAEVEGVSG FT TWKRLTENVNELAGNLTRQVRAIAEVTSAVAEGDLTRSVTVEASGEVAELGDNINAMVE FT SLRETTRANQEQDWLKTNLARISGLMQGHRDLPVVAELIMDELVPLVSAQYGAFYLAED FT GDDGPELRLVGSYGYPEDTARPNRIAFGRTLVGQAARSRRTIMVNELPPGYLTISSGLG FT EVVPAALVLLPIVVEGQVLGVIELASVAAFSQINRDFLEMLMETIGVNVNTIVANARTD FT ELLAESQRLTGELQARSAELQTQQEELQHSNAELEDKASLLAAQNRDIEAKNLQIEQAR FT QELEARAQQLSLASKYKSEFLANMSHELRTPLNSLLILAQLLAQNPSRNLTPKQVEYAG FT IIHSAGSDLLQLINDILDLSKVEAGKMDVSPERVTLRQLIEYVEATFRPMTSQKGLEFT FT VVTAPGAPADLLTDDSRLRQVLRNLLSNAVKFTERGGVELAVEPAPDDEVPGGVVRGGP FT VVAFRVKDTGIGIPEQNLESIFGAFQQADGTTSRKYGGTGLGLSITREIAQLLGGAVTV FT DSTPDRGSTFTLYLPVARPDFEDLLARAPEHLAADASSDVLDRPAPVAELTGGHRRRPR FT RLLVVEERPRGLLTLVAESVVADLTHGRDDAGDRPPLDVITAVGAEEAAGALAAEPCHC FT VVLELGMPDGEASRFLRALRGDSALASVPVLVHSGHRADAAVAEDLRSRAAGGTLEFLA FT GLDELRERIALHLAAEEPGDVLSLVRPEEPPRPDPRAGQGPPAGRTVLVVDDDARNLFA FT LSGILELHGFRVLHAENGRRGIEALVDHPEVALVLMDVMMPEMDGYTATAEIRRIPRYA FT ELPIIAVTAKAMPGDREKSLASGASDYVTKPVDTQDLIACVRRWLPA" FT misc_feature complement(72788..73132) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 117.60, E-value 2.3e-31" FT misc_feature complement(73751..74428) FT /note="Pfam match to entry PF00512 signal, Histidine FT kinase, score 211.30, E-value 1.4e-59" FT misc_feature complement(74684..75121) FT /note="Pfam match to entry PF01590 GAF, GAF domain, score FT 58.20, E-value 1.8e-13" FT repeat_region complement(75284..76600) FT /note="repeat region containing 5x degenerate repeats." FT CDS complement(77033..77467) FT /transl_table=11 FT /gene="SCO7328" FT /gene_synonym="SC4G10.07c" FT /product="putative regulatory protein." FT /note="SC4G10.07c, possible regulatory protein, len: 144 FT aa. Highly similar to Streptomyces fradiae TR:Q9Z9I5 FT (EMBL:AB024056) beta-lactamase regulator protein (139 aa), FT fasta scores opt: 530 z-score: 661.7 E(): 2.2e-29 61.5% FT identity in 122 aa overlap and Streptomyces coelicolor FT TR:Q9X7S3 (EMBL:AL049863) putative regulator protein, FT SC5H1.15C (151 aa), fasta scores opt: 178 z-score: 231.0 FT E(): 2.1e-05 30.8% identity in 130 aa overlap." FT /db_xref="GOA:Q9KY10" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9KY10" FT /protein_id="CAB92874.1" FT /translation="MAAESRWDRTLASEEITNRTASFTGELHNVTGARLVAEEFLHDLA FT RAAPPAAPEHWDDILLVVTELAANAVQYAPGPFQLRLRRTFDGVHVVMHDTNTTEPAPR FT PFHPSKGGGGIGWHLIHTLSDQVSVVTGERGKDIHVFLPW" FT CDS complement(77603..79513) FT /transl_table=11 FT /gene="SCO7329" FT /gene_synonym="SC4G10.08c" FT /product="putative long-chain-fatty-acid-CoA ligase." FT /note="SC4G10.08c, possible long-chain-fatty-acid-CoA FT ligase, len: 636 aa. Highly similar to many proposed FT long-chain-fatty-acid-CoA ligases including: Homo sapiens FT SW:LCFB_HUMAN(EMBL:D10040) long-chain-fatty-acid--CoA FT ligase 2 (EC 6.2.1.3) (698 aa), fasta scores opt: 447 FT z-score: 498.5 E(): 2.6e-20 26.3% identity in 616 aa FT overlap and several from Streptomyces coelicolor e.g. FT TR:Q9ZBW6(EMBL:AL034443) SC4B5.02C (608 aa), fasta scores FT opt: 1881 z-score: 2101.5 E(): 0 47.0% identity in 611 aa FT overlap. Contains a Pfam match to entry PF00501 FT AMP-binding, AMP-binding enzyme." FT /db_xref="GOA:Q9KY09" FT /db_xref="HSSP:1LCI" FT /db_xref="InterPro:IPR000873" FT /db_xref="UniProtKB/TrEMBL:Q9KY09" FT /protein_id="CAB92875.1" FT /translation="MHDPALAPRTVPPLTGSLADSLFETAARTPTLPMLARRRGPGSTA FT WDEVTAVEFRDTVVDLAKGLIASGISPGDRVAILARTRYEWTVFSYALWTVGAEVVPIY FT PTSSRDQVEWILRDAGCVGVLVEDEQNVMTVGSVCASLPALRHVWQLDAGALDTLVARG FT AFLPSATVDSMRRIVLPDATAVVAYTSGTSGRALGCALSHRGLAAPCDTLLAGWGHTVA FT PPGEQGAVLAYLPFSHVYGLMIQNLCVRGGFLMAHEPALTGEALSSALRSFRPTYLYAV FT PSVLEKIYKNFLRTAQQAGHGALFERAAATARDFATALERRRLGRGTGPGLDLRLQHAL FT YERTVYRRLRSALGGRVTRATSGGSPLSRELSLFYEGIGVYVHDGYGLTETSGGLTMQP FT LGREKSGTVGQPLPGMEVRVADDGEILVRGPSLFQGYVGDGTATREVLRGGWLATGDLG FT HLDAENYLAITGRKKDVIITSGGKSVAPAALEQRLRMHPLVHQAVLVGDNRPCVGALIT FT LDPEFLTHWRASLALPGDAPAREAREENALREEVARAVAAANSAVSRSESIRVFRVLPH FT PFDVAGGLLTPSMKLRRDEIVRTYSLEIDAMYEARSHRRPTTPPPQEPAGWEDADNVFL FT R" FT misc_feature complement(78002..79366) FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score -82.50, E-value 8.2e-11" FT RBS complement(79521..79525) FT CDS 79668..79904 FT /transl_table=11 FT /gene="SCO7330" FT /gene_synonym="SC4G10.09" FT /product="putative membrane protein." FT /note="SC4G10.09, possible membrane protein, len: 78 aa. FT Contains a possible membrane spanning hydrophobic domain." FT /db_xref="UniProtKB/TrEMBL:Q9KY08" FT /protein_id="CAB92876.1" FT /translation="MSYVNPDPDPRLSTGLEPGGGVPPGETPPAESSMPEAGPQDLLSN FT PAKGWAKGPMALILAVVVIFAVGLLGYALALIY" FT CDS complement(79930..81021) FT /transl_table=11 FT /gene="SCO7331" FT /gene_synonym="SC4G10.10c" FT /product="conserved hypothetical protein SC4G10.10c." FT /note="SC410.10c, unknown, len: 363 aa. Weakly similar to FT several proteins of undefined function e.g. Escherichia FT coli SW:YBDK_ECOLI(EMBL:AE000163) hypothetical 41.7 kd FT protein (372 aa), fasta scores opt: 369 z-score: 434.5 FT E(): 9.6e-17 26.8% identity in 355 aa overlap." FT /db_xref="GOA:Q9KY07" FT /db_xref="InterPro:IPR011793" FT /db_xref="UniProtKB/Swiss-Prot:Q9KY07" FT /protein_id="CAB92877.1" FT /translation="MRTVGVEEELLLVDPATGEPRALSAAVLARAFLDDSEQDVFEKEL FT HEQMLEFATHPQADMERLHAEIVRCREEAGRHAGGIGCAVAALATSPLPVTPSIGVNRR FT YEWMAEQYGVVVHEQLVLGCHVHVSVDSDEEGVAVIDRVRPWLPVLAALSANSPFWQGR FT DSSYSSYRSRVWQRWPSAGPTELFGSAERYHRRVADMLATGTVLDDGMVYFDVRLSQRY FT PTVEFRVADVCLDASTAVVLAALARALVDTAAREWRAGAEPAEHSVSLLRLAAWRAARS FT GLTSELLHPATMRRMPAESVVRDLLEHAGEALAAAGDLERVREGVEKLLRHGNGARVQR FT ELLARTGSLREVVAACVRRTQAA" FT misc_feature complement(80629..83790) FT /note="shares 99% sequence identity over 3162 bases with FT (EMBL:X73903) S.coelicolor glgBII gene." FT CDS complement(81094..83319) FT /transl_table=11 FT /gene="SCO7332" FT /gene_synonym="glgBII" FT /product="1,4-alpha-glucan branching enzyme." FT /note="SC4G10.11c, glgBII, 1,4-alpha-glucan branching FT enzyme (EC 2.4.1.18), len: 741 aa. Previously sequenced and FT characterised: Streptomyces coelicolor FT TR:Q59832(EMBL:X73903). Highly similar to Streptomyces FT coelicolor TR:CAB72416(EMBL:AL138978) 1,4-alpha-glucan FT branching enzyme, GlgBI or SC6A11.16c (774 aa), fasta FT scores opt: 3752 z-score: 4230.6 E():0 73.5% identity in FT 727 aa overlap. Contains a Pfam match to entry PF00128 FT alpha-amylase, Alpha amylase." FT /db_xref="GOA:Q59832" FT /db_xref="HSSP:1M7X" FT /db_xref="InterPro:IPR013783" FT /db_xref="UniProtKB/Swiss-Prot:Q59832" FT /protein_id="CAB92878.1" FT /translation="MALRDTSIPEPSGPVPPAPGACATAPPLDPTDRGRLLAGAHHDPH FT SLLGAHPVPGGIAFRVLRPFAREVGVVVDGERHTLASEEDGLFSGVLPLAGIPSYTLVV FT AYEQGETQETHDPYRFLPALGELDLHLIGEGRHEQLWQALGAEPMTHEGVTGTRFTVWA FT PNAQGVRVATDFTHWDGTAFPMRSLGSSGVWELFLPGVGEGTRYKFEIHSRYGHRFLKA FT DPMARAAEEPPNTASVVTASRYEWGDAQWMRTRADTPVHEAPFSVYEVHLPSWRPGLTY FT RELAEELPAYVKDLGFTHVELMPVAEHPYGPSWGYQVTGFYAPTARLGSPDDFRFLVDA FT LHRAGIGVIMDWVPAHFPKDDWALGRFDGDPLYEPGDSRRAEHPDWGTYTFDFARTEVR FT NFLVANAVYWCEEFHIDGLRVDAVASMLYLDYSRDSGQWEPNQYGGREDLAAMAFLQEM FT NATVYRRCPGVVTIAEESTAWGGVTRPTDTGGLGFGLKWNMGWMHDSLEYVAHEPVHRR FT YHHHEMTFSMVYAYSENYVLPISHDEVVHGKQALVSKMPGDWWQRRANVRAYLGFMWAH FT PGKQLLFMGQEFAQGAEWSEKQGPEWWLLDEGYHSAGDHRGVQDLVRELNTRYTRTPAL FT WQRDTDPAGFRWVSVDAAEDNVFAFLRYGTDGTPLLAVSNFSPVVRHEYGLAVGDEAVA FT WQEVLNTDAEEYGGGGVGNPDPVKPEDGSIRITLPPLATVWLMPYAL" FT misc_feature complement(81283..82524) FT /note="Pfam match to entry PF00128 alpha-amylase, Alpha FT amylase, score -42.30, E-value 2.8e-05" FT misc_feature complement(83028..92214) FT /note="shares 99.86 % sequence identity over 9187 bases FT with Streptomyces coelicolor A3(2)(EMBL:AJ001206) glycogen FT metabolism cluster II" FT CDS complement(83323..84684) FT /transl_table=11 FT /gene="SCO7333" FT /gene_synonym="pep2B" FT /gene_synonym="SC4G10.12c" FT /product="hypothetical protein." FT /note="SC4G10.12c, pep2B, unknown, len: 453 aa. Previously FT sequenced Streptomyces coelicolor TR:O70013(EMBL:AJ001206) FT hypothetical protein, Pep2 (453 aa). Highly similar to FT Streptomyces coelicolor TR:CAB72417(EMBL:AL138978) FT hypothetical 50.3 kd protein, Pep2A or SC6A11.17c (464 aa), FT fasta scores opt: 1629 z-score: 1819.8 E(): 0 55.8% FT identity in 462 aa overlap." FT /db_xref="InterPro:IPR002575" FT /db_xref="UniProtKB/TrEMBL:Q9KY05" FT /protein_id="CAB92879.1" FT /translation="MPKTAPLRTRRGQLAEPMSSLGELLRQWLPRQRWFAGKDRPVAEL FT GLLSMTELFPGCLHLLVHTGQGSVPSPGGAPPAGDCYQLLLGVREQPSPRLGRAIIGQV FT QDGPLAGRTVYDALHDPRTAQLLLERFRHPGKAGPLRFEADPARPVPGGLAPRLLDAEQ FT SNSSLIYGDEFILKLFRRIQPGVNPDLEVPDALARQGCGRVPAPVAWMRTTHPYGATLG FT VLQPFLHGASDGWTLSLNALAAGDEFTVQAHELGQAMGDVHLALASAFPVGAPGENGRT FT AAAMTERLTAAAHCVPALQPFVPGLRAAFAALSTCDWGPPAQRIHGDLHLGQVLRAGRD FT WFVIDFEGEPSRPLAERRSAHSPVRDIAGMLRSFDYAARQRRPWRPEWARRCREAFCAG FT YAARAGWDPRKKHGLLRAYETDRAVYEVLYEARHRPDWLPVPMAAIERLAVRGD" FT RBS complement(83328..83332) FT CDS complement(84713..86431) FT /transl_table=11 FT /gene="SCO7334" FT /gene_synonym="SC4G10.13c" FT /product="putative trehalose synthase." FT /note="SC4G10.13c, possible trehalose synthase, len: 572 FT aa. Previously sequenced region :Streptomyces coelicolor FT TR:O54207(EMBL:AJ001206) putative trehalose synthase (572 FT aa). Highly similar to Streptomyces coelicolor FT TR:CAB72418(EMBL:AL138978) putative alpha-amylase, FT SC6A11.18C (566 aa), fasta scores opt: 3717 z-score: 4344.1 FT E():0 92.2% identity in 566 aa overlap and Pimelobacter FT sp.TR:P72235(EMBL:D78198) trehalose synthase (573 aa), FT fasta scores opt: 2633 z-score: 3076.9 E():0 73.2% identity FT in 560 aa overlap. Contains a Pfam match to entry PF00128 FT alpha-amylase, Alpha amylase and a Prosite hit to PS01034 FT Glycosyl hydrolases family 16 active sites." FT /db_xref="GOA:O54207" FT /db_xref="HSSP:1M53" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:O54207" FT /protein_id="CAB92880.1" FT /translation="MTVNEPVPDTFEDTPAGDRHPDWFKRAVFYEVLVRSFQDSNGDGI FT GDLKGLTAKLDYLQWLGVDCLWLPPFFKSPLRDGGYDVSDYTAVLPEFGDLADFVEFVD FT AAHQRGMRVIIDFVMNHTSDQHPWFQESRKNPDGPYGDYYVWADDDTRYADARIIFVDT FT EASNWTHDPVRGQYYWHRFFSHQPDLNYENPAVQEEMLAALKFWLDLGVDGYRLDAVPY FT LYAEEGTNCENLPASHAFLKRVRREIDAQYPDTVLLAEANQWPEDVVDYFGDYSTGGDE FT CHMAFHFPVMPRIFMAVRRESRYPVSEILAKTPAIPSGCQWGIFLRNHDELTLEMVTDE FT ERDYMYAEYAKDPRMRANIGIRRRLATLLDNDRDQIELFTALLLALPGSPILYYGDEIG FT MGDNIWLGDRDAVRTPMQWTPDRNAGFSTCDPGRLYLPAIMDPVYGYQVTNVEASMASP FT SSLLHWTRRMIEIRKQNPAFGLGTYTELPSSNPAVLAFLREYEDDLVLCVNNFARFAQP FT TELDLREFAGRHPVELFGGVRFPAIGELPYLLTLGGHGFYWFRLTRVASRIGRRA" FT misc_feature complement(84842..84877) FT /note="PS01034 Glycosyl hydrolases family 16 active sites" FT misc_feature complement(85001..86350) FT /note="Pfam match to entry PF00128 alpha-amylase, Alpha FT amylase, score 274.00, E-value 2e-78" FT CDS complement(86428..88437) FT /transl_table=11 FT /gene="SCO7335" FT /gene_synonym="pep1B" FT /product="putative alpha-amylase." FT /note="SC4G10.14c, pep1B, possible alpha-amylase, len: 669 FT aa. Previously sequenced region: Streptomyces coelicolor FT TR:O70012(EMBL:AJ001206) alpha amylase family protein, Pep1 FT (669 aa). Highly similar to Streptomyces coelicolor FT TR:CAB72419(EMBL:AL138978) putative alpha-amylase, Pep1A or FT SC6A11.19C (675 aa), fasta scores opt: 4023 z-score: 4488.3 FT E(): 0 88.4% identity in 658 aa overlap. Contains a Pfam FT match to entry PF00128 alpha-amylase, Alpha amylase." FT /db_xref="GOA:Q9KY04" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/Swiss-Prot:Q9KY04" FT /protein_id="CAB92881.1" FT /translation="MRMSATVGIGRIPVRDVQPVVEYGRRPAKAVTGETFEVTATVFRE FT GHDAVAANVVLKDPEGRPGPWTPMRELAPGSDRWGATVTPGAPGNWTYRVEAWSDPVAT FT WRHAARIKVPAGIDAGLVLEEGSELYRRAAAGVPKDSGRDVLLAAATALLDDTLPVATR FT LAAALTPQVDAVLARHPLRDLVTSSDPLPLLVERERALYGAWYEFFPRSEGTPHTPHGT FT FRTAARRLPAIAAMGFDVVYLPPIHPIGTTHRKGRNNTLSATGDDVGVPWAIGSPEGGH FT DSIHPALGTLDDFDHFVTEAARHGLEIALDFALQCSPDHPWVHKHPEWFHHRPDGTIAH FT AENPPKKYQDIYPIAFDADPDGLATETVRILRHWMDHGVRIFRVDNPHTKPVAFWERVI FT ADINGTDPDVIFLAEAFTRPAMMATLAQIGFQQSYTYFTWRNTKQELTEYLEELSGEAA FT AYMRPNFFANTPDILHAYLQHGGRPAFEVRAVLAATLSPTWGIYSGYELCENTPLREGS FT EEYLDSEKYQLKPRDWTRAAREGTTIAPLVTRLNTIRREHPALHRLRNLRFHHTDNDAL FT IAYSKRVGSDVVLVVANLDPHRTQEATISLDMPQLGLDWHDSVPVHDELTGRTYHWGRA FT NYVRLEPGRAPAHVFHVRRPSAAAAPQNGGSGAS" FT RBS complement(86436..86440) FT misc_feature complement(86599..87828) FT /note="Pfam match to entry PF00128 alpha-amylase, Alpha FT amylase, score -82.10, E-value 0.0018" FT RBS complement(88439..88446) FT CDS complement(88499..88771) FT /transl_table=11 FT /gene="SCO7336" FT /gene_synonym="SC4G10.15c" FT /gene_synonym="pepA" FT /product="hypothetical protein." FT /note="SC4G10.15c, pepA, unknown, len: 90 aa. Previously FT sequenced region: Streptomyces coelicolor FT TR:O54206(EMBL:AJ001206) hypothetical protein, PepA (90 FT aa)." FT /db_xref="UniProtKB/TrEMBL:O54206" FT /protein_id="CAB92882.1" FT /translation="MLLPAKSEVARQLRHYRAWERSMLASPTDVTVRTTFEDSGYTLCV FT LMGKRCAREAADAAERYLRTSLVTHAQEQPERLAPSGHRAPSGAA" FT RBS 89051..89055 FT CDS 89064..89579 FT /transl_table=11 FT /gene="SCO7337" FT /gene_synonym="SC4G10.16" FT /gene_synonym="pepA2" FT /product="hypothetical protein." FT /note="SC4G10.16, pepA2, unknown, len: 171 aa. Previously FT sequenced region: Streptomyces coelicolor FT TR:O54205(EMBL:AJ001206) hypothetical protein, PepA2 (171 FT aa)." FT /db_xref="UniProtKB/TrEMBL:O54205" FT /protein_id="CAB92883.1" FT /translation="MKTAVPCYYHLDVEVSPERVGQVRRILAAHLRFWNLENLVEPVCS FT GAEMLLLAIDEHASDKNTSIEMWWNHQHLITAVGGNDHALRPDQDLRTCLQHLAANSDG FT WGCCATDTGAKVIWFSRRARAGERVPLVATDPEPITQEGLEVPREIMPVARVAGRARTS FT DGVLEEAR" FT RBS 89566..89571 FT CDS 89576..91723 FT /transl_table=11 FT /gene="SCO7338" FT /gene_synonym="glgX" FT /product="putative glycogen debranching enzyme." FT /note="SC4G10.17, glgX, possible glycogen debranching FT enzyme, len: 715 aa. Previously sequenced region: FT Streptomyces coelicolor TR:Q9X947(EMBL:AJ001206) (715 aa). FT Highly similar to Escherichia coli FT SW:GLGX_ECOLI(EMBL:J01616) glycogen operon protein, GlgX FT (EC 3.2.1.-) (657 aa), fasta scores opt: 1948 z-score: FT 2333.6 E():0 47.5% identity in 673 aa overlap and FT Streptomyces coelicolor TR:CAB76010(EMBL:AL157916) putative FT glycosyl hydrolase, GlgX2 or SC3D11.13c (782 aa), fasta FT scores opt: 2622 z-score: 3141.4 E(): 0 58.5% identity in FT 725 aa overlap. Contains a Pfam match to entry PF00128 FT alpha-amylase, Alpha amylase." FT /db_xref="GOA:Q9KY03" FT /db_xref="HSSP:1BF2" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:Q9KY03" FT /protein_id="CAB92884.1" FT /translation="MTRARPNWKGSPVWSGHPYPLGAAYDGQGTNFALFSEVAERVDLV FT LVDDDGNHSTVPLPDVDGFVWHCYLPGVGPGQRYGYRVHGPWAPAVGHRCNPAKLLLDP FT YTRAVDGLVDNHASLFERARGKADPGDSAGHTMLGVVTDPFFDWGDDRPPRRPYSESVI FT YEAHVRGLSRTHPDVPEELRGTYAGLAHPAVVDHLTSLGVTAVELMPVHQFVHDGVLLD FT RGLSNYWGYNTIGFFAPHNGYAALGTRGQQVSEFKSMVKTLHEAGLEVILDVVYNHTAE FT GNERGPTLSFRGIDNASYYRLVDGDWQHYYDTTGTGNSLLMRHPYVLQLIMDSLRYWVT FT EMHVDGFRFDLAATLARQFHEVDRLSAFFDLIQQDPVISRVKLIAEPWDVGEGGYQVGN FT FPQLWSEWNGKYRDAVRDFWRAEDHSLGEFASRLTGSSDLYQHSRRRPRASVNFVTAHD FT GFTLRDLVSYNDKHNEANGEDNRDGESHNRSWNCGAEGGTKDPAVRELRGRQQRNFLAT FT LLLSQGIPMICHGDELGRTQRGNNNAYCQDNEISWIDWRLDGEQRALLDFARRLIALRA FT DHPVLRRRRFFHGETLTHADQPLPDLVWLLPDAREMTDDDWQRSDAHTVGVFLNGDAIA FT EPDPRGRPVVDDSFLLLLNSHWEPADFRLPDAGYGERWTALVDTADPDGVPDEAEHKAG FT TRLTVEQRSLVLLSRPSRTGR" FT misc_feature 90059..91402 FT /note="Pfam match to entry PF00128 alpha-amylase, Alpha FT amylase, score 31.60, E-value 1.1e-08" FT CDS complement(91726..92562) FT /transl_table=11 FT /gene="SCO7339" FT /gene_synonym="SC4G10.18c" FT /product="conserved hypothetical protein SC4G10.18c." FT /note="SC410.18c, unknown, len: 278 aa. Partially sequenced FT previously: Streptomyces coelicolor FT TR:Q9X946(EMBL:AJ001206) hypothetical 17.2 kd protein (>161 FT aa). Also highly similar to Streptomyces griseus FT TR:P95754(EMBL:D89734) SgaA protein, a suppressor of growth FT disturbance in the presence of high osmolarity and high FT concentrations of A-factor (264 aa), fasta scores opt: 807 FT z-score: 948.0 E():0 52.0% identity in 250 aa overlap." FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/TrEMBL:Q9KY02" FT /protein_id="CAB92885.1" FT /translation="MTAGGRDQDATAMNHDTTSSTRGESLLSTHSVYGAPCWVSLTSRD FT LEATEDFYSAVLGWRWRPVRLGEPFRIALADGVPVAGIAAVAAMWQMAVAWTPYFAVRS FT ADEAVSRAQERGGTAAVGPISLPPGRAALLADRDGATFGIWEGELFSDWDAWRTKRPAF FT IRLHTRDAFDAAIFYGEIFEWASGQGCEVRYEGDEVVLRHEGEVVARIESGALGAAPDP FT AVRPHWQVHFAVEDVTACARAAERHGGSVLSLGADEAVLRDADGAQFTVTARRLGS" FT CDS 92652..93017 FT /transl_table=11 FT /gene="SCO7340" FT /gene_synonym="SC4G10.19" FT /product="hypothetical protein SC4G10.19." FT /note="SC410.19, unknown, len: 121 aa. Similar to FT Streptomyces coelicolor TR:Q9S1U3(EMBL:AL109950) FT hypothetical 11.6 kd protein, SCJ4.30 (107 aa), fasta FT scores opt: 285 z-score: 344.7 E(): 9.8e-12 54.3% identity FT in 92 aa overlap." FT /db_xref="InterPro:IPR005561" FT /db_xref="UniProtKB/TrEMBL:Q9KY01" FT /protein_id="CAB92886.1" FT /translation="MPSTDVRPDPGPDSDPDQIFRLQEQVRQLKEAVVSHAVVDQAIGV FT VIALGGVTPDEGWIVLKEVSQHTNIKLRNVAEAILIWGRTGVIPPEILTVLEDRLGRPG FT LSGPPPGSPHVSGRSSR" FT misc_feature complement(92704..94713) FT /note="shares 99.86% sequence identity over 2010 bases with FT Streptomyces coelicolor (EMBL:AF036131) putative RNA FT polymerase secondary sigma factor (sigG) gene, complete FT cds." FT CDS complement(92965..93756) FT /transl_table=11 FT /gene="SCO7341" FT /gene_synonym="SC4G10.20c" FT /gene_synonym="sigG" FT /product="putative RNA polymerase secondary sigma factor" FT /note="SC4G10.20c, sigG, possible RNA polymerase secondary FT sigma factor, len: 263 aa. Previously sequenced region: FT Streptomyces coelicolor TR:O52313 (EMBL:AF036131) (263 aa). FT Highly similar to Streptomyces coelicolor SW:RPOF_STRCO FT (EMBL:L11648) RNA polymerase sigma-F factor (287 aa), fasta FT scores opt: 682 z-score: 820.1 E(): 0 49.2% identity in 240 FT aa overlap. Contains a Prosite hit to PS00339 FT Aminoacyl-transfer RNA synthetases class-II signature 2 and FT a Pfam match to entry PF00140 sigma70, Sigma-70 factor. A FT possible helix-turn-helix motif situated between residues FT 227..248 (+6.87 SD)." FT /db_xref="GOA:O52313" FT /db_xref="HSSP:1L0O" FT /db_xref="InterPro:IPR014322" FT /db_xref="UniProtKB/TrEMBL:O52313" FT /protein_id="CAB92887.1" FT /translation="MRVAGRTQPHPHDDAPDTAAAFERLAGLPEGPERKALRDDLIRVW FT LPMAERIAVRFRGRGENLEDLYQVAALGLVKAVDHYDPERGHAFEAYAVPTVTGEIKRH FT FRDHMWTLHVPRRIQDLRNRVRKSAKELAQTTPGRAPTVEEIAEHAQLTTAEVRTGMEA FT LECFSALSLEAEMPGTDGYALGDALGGPDPAFDAVVDRVAVRPCLEALPERERTILYLR FT FFGGMTQSRIAQQLGISQMHVSRLLTGCFDRIREEILAEAR" FT misc_feature complement(92989..93654) FT /note="Pfam match to entry PF00140 sigma70, Sigma-70 FT factor, score 200.50, E-value 2.6e-56" FT misc_feature complement(93673..93702) FT /note="PS00339 Aminoacyl-transfer RNA synthetases class-II FT signature 2" FT RBS complement(93763..93769) FT CDS 94060..94584 FT /transl_table=11 FT /gene="SCO7342" FT /gene_synonym="SC4G10.21" FT /product="hypothetical protein SC4G10.21." FT /note="SC410.21, unknown, len: 174 aa. Previously sequenced FT region: Streptomyces coelicolor TR:O52312(EMBL:AF036131) FT (174 aa)." FT /db_xref="UniProtKB/TrEMBL:O52312" FT /protein_id="CAB92888.1" FT /translation="MYEPNVVGDWQEYDEHAGLRVRVHRLEPAEPPRGRDDAAEGLTYF FT RVRVTVENRGVRHLGIHLEDGQIDVRIGPDGESAFLDWRNSQFIEGFDVYPLRRATAVL FT YAAGPEASLSQVDVQVQLRVDEEWADRRLWSGAPGLPDGAGAAPCGGVRDEGLVHQVSA FT YLRGQSEEGTA" FT CDS complement(94604..95545) FT /transl_table=11 FT /gene="SCO7343" FT /gene_synonym="hemC" FT /product="porphobilinogen deaminase." FT /note="SC4G10.22c, hemC, porphobilinogen deaminase (EC FT 4.3.1.8). len: 313 aa. Highly similar to many e.g. FT Escherichia coli SW:HEM3_ECOLI(EMBL:X04242) porphobilinogen FT deaminase (EC 4.3.1.8) (313 aa), fasta scores opt: 710 FT z-score: 839.8 E(): 0 42.2% identity in 303 aa overlap. FT Contains a Pfam match to entry PF01379 Porphobil_deam, FT Porphobilinogen deaminase." FT /db_xref="GOA:Q9KY00" FT /db_xref="HSSP:1PDA" FT /db_xref="InterPro:IPR000860" FT /db_xref="UniProtKB/Swiss-Prot:Q9KY00" FT /protein_id="CAB92889.1" FT /translation="MRMSAPELIRIVSRDSPMALAQVERVRAELAALHPGVRTEVVPVR FT TTGDKWLGDLSQVEGKGAFTKEVDAALLSGEADLAVHCVKDVPADRPLPAGTVFAAFLK FT RDDVRDALVHPDGLTLDELPDGTRVGTSSVRRVAQLAATHPHLRCVPFRGNANRRLAKL FT AAGEADALLLAVSGLERIGRTDVISEVLSTETMMPPIGAGILALQCREGDRALIEAVSA FT LGDPRTHREATAERMFLHVLQGHCNSPIAGHAQVDRSGELSLRACVFTPDGKVRLNAHE FT WAGRLDPATLGTSVAVALLRQGAREIIDGIAH" FT misc_feature complement(94643..95521) FT /note="Pfam match to entry PF01379 Porphobil_deam, FT Porphobilinogen deaminase, score 301.00, E-value 1.5e-86" FT CDS complement(95613..96389) FT /transl_table=11 FT /gene="SCO7344" FT /gene_synonym="SC4G10.23c" FT /product="putative secreted protein" FT /note="SC4G10.23c, possible secreted protein, len: 258 aa. FT Weakly similar to the Eukaryotic protein elicitor from FT Pythium aphanidermatum TR:Q9SPD4(EMBL:AF179598) 25 kda FT protein elicitor (234 aa), fasta scores opt: 279 z-score: FT 316.6 E(): 3.6e-10 31.0% identity in 242 aa overlap. FT Contains a possible N-terminal signal sequence" FT /db_xref="InterPro:IPR008701" FT /db_xref="UniProtKB/TrEMBL:Q9KXZ9" FT /protein_id="CAB92890.1" FT /translation="MSPRTPTTPRRRWLTVPLGALALVVAFPATAFAAPPPGLPGNADG FT LERMYQPAYDYDTDGCYPTPAIGADGAVNGGLNPTGALNGNCRDASDLDNTNGYARAKC FT DGDWCAYMYGLYFEKDQALPGTSLGGHRHDWEHVVVWVREGTVQYVSTSNHGSFSVHER FT SAVRFDGTHPKIVYHKDGIGTHCFRPATAGDEPPENHKGAWQYPALVGWNGYPAGLREK FT LSGYDFGSANFGLKDGSFASHLAAAKPAGIPFDPNA" FT CDS complement(96531..97511) FT /transl_table=11 FT /gene="SCO7345" FT /gene_synonym="SC4G10.24c" FT /product="probable ATP-dependent DNA ligase." FT /note="SC4G10.24c, probable ATP-dependent DNA ligase, len: FT 326 aa. Similar in parts to many DNA ligases e.g. FT Pyrococcus horikoshii SW:DNLI_PYRHO(EMBL:AP000006) probable FT thermostable DNA ligase (EC 6.5.1.1) (559 aa), fasta scores FT opt: 454 z-score: 506.0 E(): 1e-20 32.0% identity in 344 aa FT overlap. Contains a Prosite hit to PS00697 ATP-dependent FT DNA ligase AMP-binding site and a Pfam match to entry FT PF01068 DNA_ligase, DNA ligase." FT /db_xref="GOA:Q9KXZ8" FT /db_xref="InterPro:IPR014146" FT /db_xref="UniProtKB/TrEMBL:Q9KXZ8" FT /protein_id="CAB92891.1" FT /translation="MELPPIPPMLATPGTLPPAGQDTRWAYETKQDGQRVVVYLPGDGS FT VLLRARSGQDITAAYPELAPLATALGGTPAVLDGEVLALDEQGRADFQLLQSRMGLAHT FT PARAAHRAAKVPVHLVLFDALHLAGRSLLRLPYTGRRERLTDLGLNGPSWSTPAALVGH FT GAQALRATREHGLEGLVCKRLDSVYEPGVRSRAWIKIRNMRSEDVVVGGWLPGKGRLGG FT LPGAVLVGQRAAGRLRYVGGVGTGWSAGERTELAALLAAAASDVCPFDPVPRVPGARWV FT VPRLVGEVRYSTRTREGMLRQPSWLRLRPDLAPEESAADLPDDLA" FT misc_feature complement(96585..97499) FT /note="Pfam match to entry PF01068 DNA_ligase, DNA ligase, FT score 118.70, E-value 1.1e-31" FT misc_feature complement(97404..97430) FT /note="PS00697 ATP-dependent DNA ligase AMP-binding site" FT CDS complement(97608..99062) FT /transl_table=11 FT /gene="SCO7346" FT /gene_synonym="SC4G10.25c" FT /product="putative membrane transport protein." FT /note="SC4G10.25c, possible membrane transport protein, FT len: 484 aa. Highly similar to several including: FT Streptomyces glaucescens SW:TCMA_STRGA(EMBL:M80674) FT tetracenomycin C resistance and export protein, TcmA (528 FT aa), fasta scores opt: 538 z-score: 582.2 E(): 5.8e-25 FT 27.8% identity in 475 aa overlap and Streptomyces FT coelicolor TR:CAB88188(EMBL:AL352972) putative transport FT protein (fragment), SCC30.18 (348 aa), fasta scores opt: FT 1368 z-score: 1475.7 E():0 60.0% identity in 340 aa FT overlap. Contains multiple possible membrane spanning FT hydrophobic domains and a Pfam match to entry PF00083 FT sugar_tr, Sugar (and other) transporter." FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9KXZ7" FT /protein_id="CAB92892.1" FT /translation="MPASPASPRPNAVVAVLALAGIVVALMQTLVIPIIPELPKLLDAS FT ASDAAWAVTATLLASAVATPVVGRLGDMFGKRRMLLLSLVLLIAGSAVCGLSDALVPMV FT VGRALQGLSAAVIPLGISIMRDELPVERLAGATAVMSASLGVGGALGLPAAALIADKLD FT WHMLFWLSGTLGAVSLVLVLTLVPESAVRTGGRFDLLGGIGMAAGLASLLLAISKGGDW FT GWTSGTTLGLFAAAVVILLVWGWWELHTPEPLVDLRTTARRQVLFTNLASVAIGFSMFA FT MSLVLPQLLQLPEATGYGLGRSLLTTGLVMAPSGLVMMAFAPVSAKVSKSRGPKVTLMI FT GALIVAAGYGLNIVLMAEVWHLVLVSCVISAGIGFAYGAMPSLIMGAVPPSETAAANSL FT NTLMRSLGTSVASAIAGVILAQMTIDLGGFALPSENAFKVVMAIGAGAALLATALASFI FT PRHRPAGTPAGPVPADGAASEPASVR" FT misc_feature complement(97677..99026) FT /note="Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter, score -76.40, E-value 0.00039" FT CDS 99299..99964 FT /transl_table=11 FT /gene="SCO7347" FT /gene_synonym="SC9H11.01" FT /gene_synonym="SC4G10.26." FT /product="hypothetical protein" FT /note="SC9H11.01, unknown, partial CDS, len: >201 aa." FT /note="SC410.26, unknown, partial CDS, len: >55 aa. FT Overlaps and extends into CDS SC9H11.01 on the adjoining FT cosmid." FT /db_xref="GOA:Q8CJK3" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q8CJK3" FT /protein_id="CAD55397.1" FT /translation="MVIMAGKAVRTEQVSATRQLILTTAERLFAEHGVYAVSNRQVSEA FT AGQGNNAAVGYHFGTKTDLVRAIAQRHSERVEELRARQLAALGDSPDLRDWVDCLVRPQ FT FDHLAALGSPTWYARFCAQVMTDPALRQIMTEESRASVSLRAIIVGRNRCMPALPDEVR FT AERGDMARHLIVHTAEERERALAENRPTPRASWQDAADGLVDAIVGMWLAPVTPRGGG" FT repeat_region 100131..100165 FT /note="SC9H11 repeat unit 1 (RU1). Repeated three times on FT this cosmid (iterated at positions 965..999 and 1156..1190) FT with the consensus: FT GCTG(C/T)GAGGGGCGGCGCGGTGGGCCGGCCGGTCGA." FT repeat_region 100166..100172 FT /note="SC9H11 repeat unit 2 (RU2). Repeated three times FT (alternate positions 1000..1006 and 1192..1198) with the FT consensus: AGCCCGT." FT repeat_region 100173..100185 FT /note="SC9H11 repeat unit 3 (RU3). Repeated six times on FT this cosmid (iterated at positions 849..861, 1007..1019, FT 1040..1052, 1212..1224 and 1245..1257) with the consensus: FT CGCAC(T/G)TCGGCGT. This repeat differs only slightly from FT RU4." FT repeat_region 100186..100198 FT /note="SC9H11 repeat unit 4 (RU4). Repeated four times on FT this cosmid (iterated at positions 1020..1032, 1199..1211 FT and 1225..1237) with the consensus: CGGACGTCGGCGT. This FT repeat differs only slightly from RU3." FT repeat_region 100199..100205 FT /note="SC9H11 repeat unit 5 (RU5). Repeated three times on FT this cosmid (iterated at positions 1033..1039 and FT 1238..1244) with the consensus: TGCTCAC." FT CDS complement(100202..100315) FT /transl_table=11 FT /gene="SCO7348" FT /gene_synonym="SC9H11.02c" FT /product="hypothetical protein SC9H11.02c." FT /note="SC9H11.02c, doubtful CDS, len: 37 aa. Highly similar FT to predicted sequences encoded within repeat unit 7 on this FT cosmid: SC9H11.03c (37 aa), fasta scores opt: 244 z-score: FT 268.5 E(): 2e-09 91.9% identity in 37 aa and the C-terminal FT 37 aa of SC9H11.04c (398 aa), fasta scores opt: 225 FT z-score: 234.8 E(): 1.5e-07 91.9% identity in 37 aa overlap FT overlap." FT /db_xref="UniProtKB/TrEMBL:Q9KYN7" FT /protein_id="CAB92191.1" FT /translation="MALPAVGRLLQCGPREPAPPPAPPALGSRTAHDADVR" FT repeat_region 100206..100218 FT /note="SC9H11 repeat unit 3 (RU3). Repeated six times on FT this cosmid (iterated at positions 816..828, 1007..1019, FT 1040..1052, 1212..1224 and 1245..1257) with the consensus: FT CGCAC(T/G)TCGGCGT. This repeat differs only slightly from FT RU4." FT repeat_region 100219..100227 FT /note="SC9H11 repeat unit 6 (RU6). Repeated three times FT (iterated at positions 1053..1061 and 1258..1266) with the FT consensus: CG(T/C)GTG(C/T)CG." FT repeat_region 100228..100321 FT /note="SC9H11 repeat unit 7 (RU7). Repeated three times on FT this cosmid (iterated at positions 1062..1155 and FT 1267..1359) with the consensus: FT TCCGTGACCCGAGGGC(G/A)GGCGGTG(C/T)CGGGGGCGGGGCCGGCTCGCGC FT (G/A)GGCCG(C/T)AC(T/A)GGAGCAGCCTGCCCACGGCGGGCAGCGCCACC FT (G/-)(C/A)(G/A)CG." FT repeat_region 100322..100356 FT /note="SC9H11 repeat unit 1 (RU1). Repeated three times on FT this cosmid (iterated at positions 774..808 and 1156..1190) FT with the consensus: FT GCTG(C/T)GAGGGGCGGCGCGGTGGGCCGGCCGGTCGA." FT repeat_region 100357..100363 FT /note="SC9H11 repeat unit 2 (RU2). Repeated three times FT (alternate positions 774..808 and 1192..1198) with the FT consensus: AGCCCGT." FT repeat_region 100364..100376 FT /note="SC9H11 repeat unit 3 (RU3). Repeated six times on FT this cosmid (iterated at positions 816..828, 849..861, FT 1040..1052, 1212..1224 and 1245..1257) with the consensus: FT CGCAC(T/G)TCGGCGT. This repeat differs only slightly from FT RU4." FT repeat_region 100377..100389 FT /note="SC9H11 repeat unit 4 (RU4). Repeated four times on FT this cosmid (iterated at positions 829..841, 1199..1211 and FT 1225..1237) with the consensus: CGGACGTCGGCGT. This repeat FT differs only slightly from RU3." FT repeat_region 100390..100396 FT /note="SC9H11 repeat unit 5 (RU5). Repeated three times on FT this cosmid (iterated at positions 842..848 and 1238..1244) FT with the consensus: TGCTCAC." FT CDS complement(100393..100506) FT /transl_table=11 FT /gene="SCO7349" FT /gene_synonym="SC9H11.03c" FT /product="hypothetical protein SC9H11.03c." FT /note="SC9H11.03c, doubtful CDS, len: 37 aa. Highly similar FT to predicted sequences encoded within repeat unit 7 on this FT cosmid: SC9H11.02c (37 aa), fasta scores opt: 244 z-score: FT 268.5 E(): 2e-09 91.9% identity in 37 aa and the C-terminal FT 37 aa of SC9H11.04c (398 aa), fasta scores opt: 205 FT z-score: 222.0 E(): 7.9e-07 83.8% identity in 37 aa FT overlap." FT /db_xref="UniProtKB/TrEMBL:Q9KYN6" FT /protein_id="CAB92192.1" FT /translation="MALPAVGRLLQCGPREPAPPPTPPALGSRTTRDADVR" FT repeat_region 100397..100409 FT /note="SC9H11 repeat unit 3 (RU3). Repeated six times on FT this cosmid (iterated at positions 816..828, 849..861, FT 1007..1019, 1212..1224 and 1245..1257) with the consensus: FT CGCAC(T/G)TCGGCGT. This repeat differs only slightly from FT RU4." FT repeat_region 100410..100418 FT /note="SC9H11 repeat unit 6 (RU6). Repeated three times FT (iterated at positions 862..870 and 1258..1266) with the FT consensus: CG(T/C)GTG(C/T)CG." FT misc_feature 100419..100512 FT /note="SC9H11 repeat unit 7 (RU7). Repeated three times on FT this cosmid (iterated at positions 871..964 and 1267..1359) FT with the consensus: FT TCCGTGACCCGAGGGC(G/A)GGCGGTG(C/T)CGGGGGCGGGGCCGGCTCGCGC FT (G/A)GGCCG(C/T)AC(T/A)GGAGCAGCCTGCCCACGGCGGGCAGCGCCACC FT (G/-)(C/A)(G/A)CG." FT repeat_region 100513..100547 FT /note="SC9H11 repeat unit 1 (RU1). Repeated three times on FT this cosmid (iterated at positions 774..808 and 965..999) FT with the consensus: FT GCTG(C/T)GAGGGGCGGCGCGGTGGGCCGGCCGGTCGA." FT repeat_region 100549..100555 FT /note="SC9H11 repeat unit 2 (RU2). Repeated three times FT (alternate positions 774..808 and 1000..1006) with the FT consensus: AGCCCGT." FT repeat_region 100556..100568 FT /note="SC9H11 repeat unit 4 (RU4). Repeated four times on FT this cosmid (iterated at positions 829..841, 1020..1032 and FT 1225..1237) with the consensus: CGGACGTCGGCGT. This repeat FT differs only slightly from RU3." FT repeat_region 100569..100581 FT /note="SC9H11 repeat unit 3 (RU3). Repeated six times on FT this cosmid (iterated at positions 816..828, 849..861, FT 1007..1019, 1040..1052 and 1245..1257) with the consensus: FT CGCAC(T/G)TCGGCGT. This repeat differs only slightly from FT RU4." FT repeat_region 100582..100594 FT /note="SC9H11 repeat unit 4 (RU4). Repeated four times on FT this cosmid (iterated at positions 829..841, 1020..1032 and FT 1199..1211) with the consensus: CGGACGTCGGCGT. This repeat FT differs only slightly from RU3." FT repeat_region 100595..100601 FT /note="SC9H11 repeat unit 5 (RU5). Repeated three times on FT this cosmid (iterated at positions 842..848 and 1033..1039 FT with the consensus: TGCTCAC." FT CDS complement(100598..101794) FT /transl_table=11 FT /gene="SCO7350" FT /gene_synonym="SC9H11.04c" FT /product="putative membrane efflux protein." FT /note="SC9H11.04c, possible membrane efflux protein, len: FT 398 aa. Similar to many membrane efflux proteins including: FT Streptomyces lividans SW:CMLR_STRLI(EMBL:X59968) FT chloramphenicol resistance protein, CmlR (392 aa), fasta FT scores opt: 227 z-score: 239.8 E(): 6.8e-06 27.7% identity FT in 411 aa overlap and Escherichia coli FT SW:FSR_ECOLI(EMBL:D73370) fosmidomycin resistance protein, FT FsR (406 aa), fasta scores opt: 506 z-score: 524.2 E(): FT 9.8e-22 28.4% identity in 373 aa overlap. Contains multiple FT possible membrane spanning hydrophobic domains. Note that FT the C-terminal 37 aa of this protein are highly similar to FT CDS SC9H11.02c and SC9H11.03c." FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9KYN5" FT /protein_id="CAB92193.1" FT /translation="MTPTRDRPLVLLSFGHACVDVYQGSVAALVPYFVAERAYGYAAAS FT GVVLAASLLSSLVQPLFGALTDRRALPWLLPSSTLTAGAGVALGGVTDSYPLTLAAVAA FT GGVGIAAYHPEAARAARAAAGGSHTAMGWFSLGGNAGFALAPPLVWAVVGGGGLGASWL FT LALPAVAGAVLCGVAVRSAGAARAAGGRTTVAAGSDDWASFLRLTGAVVCRSVVFAGLS FT TFVALYVRERVGGGSAAGTAALFVLYLGGAVGTVAGGRLADRYGRLRVVRRSYVLTVLA FT VAGVVLVPGPPVYLFVALTSAGLYVPFSLHITLGQDYLPRRVGTASGVTLGLAVSVGGL FT AAPALGALADASSLGTALLPLVALPAVGRLLLYGLREPAPPPAPPALGSRTAHDADVR" FT repeat_region 100602..100614 FT /note="SC9H11 repeat unit 3 (RU3). Repeated six times on FT this cosmid (iterated at positions 816..828, 849..861, FT 1007..1019, 1040..1052 and 1212..1224) with the consensus: FT CGCAC(T/G)TCGGCGT. This repeat differs only slightly from FT RU4." FT repeat_region 100615..100623 FT /note="SC9H11 repeat unit 6 (RU6). Repeated three times FT (iterated at positions 862..870 and 1053..1061) with the FT consensus: CG(T/C)GTG(C/T)CG." FT repeat_region 100624..100716 FT /note="SC9H11 repeat unit 7 (RU7). Repeated three times on FT this cosmid (iterated at positions 871..964 and 1062..1155) FT with the consensus: FT TCCGTGACCCGAGGGC(G/A)GGCGGTG(C/T)CGGGGGCGGGGCCGGCTCGCGC FT (G/A)GGCCG(C/T)AC(T/A)GGAGCAGCCTGCCCACGGCGGGCAGCGCCACC FT (G/-)(C/A)(G/A)CG." FT CDS 101849..102718 FT /transl_table=11 FT /gene="SCO7351" FT /gene_synonym="SC9H11.05" FT /product="putative AraC-family transcriptional regulator." FT /note="SC9H11.05, possible AraC-family transcriptional FT regulator, len: 289 aa. Similar to several including: FT Streptomyces coelicolor TR:O69819(EMBL:AL023496) FT transcriptional regulator, SC1A6.14 (256 aa), fasta scores FT opt: 397 z-score: 464.2 E(): 2.2e-18 33.5% identity in 254 FT aa overlap and Escherichia coli FT SW:YEAM_ECOLI(EMBL:AE000274) hypothetical transcriptional FT regulator (273 aa), fasta scores opt: 438 z-score: 510.8 FT E(): 5.4e-21 33.2% identity in 232 aa overlap. Contains a FT Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory FT helix-turn-helix proteins, araC family with the putative FT helix-turn-helix motif situated between residues 194..215 FT (+4.88 SD). Contains a TTA /leucine codon which is a FT possible target for bldA regulation." FT /db_xref="GOA:Q9KYN4" FT /db_xref="InterPro:IPR018060" FT /db_xref="UniProtKB/TrEMBL:Q9KYN4" FT /protein_id="CAB92194.1" FT /translation="MSNIRHTNVGQPGLRQPGIRQPGIRESAIRQPDVRHTPVAPTRAQ FT RLDAGQRIDAHRHDEHQIVHAGSGVVAVTTESGTWFAPGTRAIWIPAGTVHAHRAHGRL FT DLHLVGLPADANPLGLDSPAVLAVGPLLRELIVAYTLDPRDTGPERGRLLAVLCDQLRA FT SPQQPLRLPTPRDPRLAEVCALVHADPADTRTLAALGAATGTAERTLSRLFRREFGMTF FT PQWRTQSRLYHALRMLADDLPVTTVAHRCGWSSASAFIDVFRRAFGCTPGTHNRRVGTA FT HPPVLTVE" FT misc_feature 102353..102355 FT /note="TTA /leucine codon, possible target for bldA FT regulation." FT misc_feature 102425..102682 FT /note="Pfam match to entry PF00165 HTH_AraC, Bacterial FT regulatory helix-turn-helix proteins, araC family, score FT 72.00, E-value 1.3e-17" FT RBS 102741..102746 FT CDS 102751..103131 FT /transl_table=11 FT /gene="SCO7352" FT /gene_synonym="SC9H11.06" FT /product="putative membrane protein." FT /note="SC9H11.06, possible membrane protein, len: 126 aa. FT Similar to several proteins of undefined function from FT Deinococcus radiodurans e.g. TR:AAF11579(EMBL:AE002039) FT hypothetical 13.2 kd protein (120 aa), fasta scores opt: FT 304 z-score: 370.4 E(): 3.6e-13 48.2% identity in 112 aa FT overlap. Contains multiple possible membrane spanning FT hydrophobic domains." FT /db_xref="UniProtKB/TrEMBL:Q9KYN3" FT /protein_id="CAB92195.1" FT /translation="MSRSERSPLLLAGLLATAGVAHFAQPRPFDATVPRSLPGSPRAWT FT YASGVAELALAAGLAVPRTRRAAALSAAAFFVGVFPANVKMAWDWRHRPAPQQAAALGR FT LPVQVPLVLWARAVAQSTGSRS" FT RBS 103118..103121 FT CDS 103128..103595 FT /transl_table=11 FT /gene="SCO7353" FT /gene_synonym="SC9H11.07" FT /product="conserved hypothetical protein SC9H11.07" FT /note="SC9H11.07, unknown, len: 155 aa. Highly similar to FT many bacterioferritin comigratory proteins e.g. FT Mycobacterium tuberculosis TR:O53911(EMBL:AL02200) putative FT bacterioferritin comigratory protein, BcpB (154 aa), fasta FT scores opt: 618 z-score: 761.9 E():0 63.8% identity in 149 FT aa overlap. Contains a Pfam match to entry PF00578 FT AhpC-TSA, AhpC/TSA family" FT /db_xref="GOA:Q9KYN2" FT /db_xref="InterPro:IPR012335" FT /db_xref="UniProtKB/TrEMBL:Q9KYN2" FT /protein_id="CAB92196.1" FT /translation="MSALPAVGDTVEDFTLPDETGTPRRLSELLADGPVVLFFYPAALT FT TGCTAEACHFRDLAAEFAAVGARPVGVSGDPVERQQEFAGRHTLGMPLLSDTDGAVRER FT FGVKRGFSLAPTKRVTFVVGQDRTLLEVVRSEIRMNTHADRALAALRAHRP" FT misc_feature 103146..103568 FT /note="Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA FT family, score 61.90, E-value 1.4e-14" FT CDS 103621..106029 FT /transl_table=11 FT /gene="SCO7354" FT /gene_synonym="SC9H11.08" FT /product="conserved hypothetical protein SC9H11.08." FT /note="SC9H11.08, unknown, len: 802 aa. Similar to many FT proteins of undefined function e.g. Streptomyces coelicolor FT TR:CAB61537(EMBL:AL133171) hypothetical 89.7 kd protein, FT SCF81.26 (835 aa), fasta scores opt: 2446 z-score: 2641.1 FT E(): 0 53.0% identity in 800 aa overlap. Contains Pfam FT matches to 2xentry PF00989 PAS, PAS domain." FT /db_xref="GOA:Q9KYN1" FT /db_xref="InterPro:IPR010822" FT /db_xref="UniProtKB/TrEMBL:Q9KYN1" FT /protein_id="CAB92197.1" FT /translation="MIPHRPGMILDGMEDSSAAMTVDARGLVTGWSDGARRLTGHAAEE FT VVGRPARDLLARGAPTRPLSRADPAGTALSGTVVVRHRDGRPVSLGLRIRPLRGADGAP FT GGYLATADVPGGPAPALIDDAVRQASLSMSVLDPELRFVHVNDTACRMMGRPAEELLGR FT SLSDTLADFEGDPRSFLHHLRVAADRGRPVQYESYAPAPAGSCLHAWTVEIWPVHDASG FT TLTAVAMAALESTEQHRARERLALLNAAGAVGSTLDVVRTAEELVGLLVPRFAGFASVD FT LLDWVLGTDEPLAVPPGSGELRRVAHASATEGFPTPAVHLGGQEIHPSDSPPVRAVREG FT RVVLSGPGDPDFDRWMRTREAETPHNRPFREAVCSTLSVPLRARGTTLGVVLAARTAPR FT EPYAAEDAVLAEELVSRAAVSMDNARRFARERSTALAIQHSLLPRDLPGQAAVEVAHRY FT LPSASAAGIGGDWFDVIPLSGTRVGLVVGDVVGHGIPSTATMGRLCTAVRTLADVDLPP FT DELLTHLDDLVSHLAAGGAYDGGGTEAAELGATCLYAVYDPVSRRLALAAAGHPAPALL FT LPDGTTRLVDMTAGPPLGVGGLPFEATELELPEGSVVALYTDGLVEDRDRDVDHATTEL FT CRALAAPATSLEALCDGVLKAVLPEEPGDDVALLLARTRALGEDRVRTWDVPPDPAGVA FT AARRSVGEQLTAWGLDDTAFVTELVVSELVTNAIRYGEPPIQLRLIRHTALICEVSDAS FT STSPHLRRAHAFDEGGRGLLLVAQLTQRWGSRQTDTGKTIWAEQPLPPE" FT misc_feature 103684..103785 FT /note="Pfam match to entry PF00989 PAS, PAS domain, score FT 21.50, E-value 0.00025" FT misc_feature 103978..104121 FT /note="Pfam match to entry PF00989 PAS, PAS domain, score FT 19.30, E-value 0.00098" FT CDS complement(106062..106703) FT /transl_table=11 FT /gene="SCO7355" FT /gene_synonym="SC9H11.09c" FT /product="conserved hypothetical protein SC9H11.09c" FT /note="SC9H11.09c, unknown, len: 213 aa; similar to the FT N-terminal region of many ATP-dependent DNA ligases, e.g. FT TR:Q98J69 (EMBL:AP002998) Rhizobium loti (Mesorhizobium FT loti) probable ATP-dependent DNA ligase MLL2077, 833 aa; FT fasta scores:opt: 539 Z-score: 543.3 E(): 1.3e-22; 53.216% FT identity in 171 aa overlap" FT /db_xref="InterPro:IPR014144" FT /db_xref="UniProtKB/TrEMBL:Q9KYN0" FT /protein_id="CAB92198.1" FT /translation="MDGEDDGLRDYHGKRDFGRTGEPAGPGAPGEGGAPGGDGPPRFVV FT QIHDASTLHFDFRLQVADVLKSWSVPKGPSADPRDKRLAVPTEDHPLEYEEFEGVIPAG FT EYGGGTVIVWDHGTYEPLSHDRRGRPVDFAESLAHGHARFRLHGAKLRGEYALTRFRGG FT PDGDAGADAAWLLVKTAGGGRGHGTPDPRRARSARTGRTLARVAAEHGEE" FT CDS complement(106760..107590) FT /transl_table=11 FT /gene="SCO7356" FT /gene_synonym="SC9H11.10c" FT /product="oxidoreductase." FT /note="SC9H11.10c, oxidoreductase, len: 276 aa. Highly FT similar to many including: Corynebacterium sp. FT SW:2DKG_CORSP(EMBL:M21193) 2,5-diketo-d-gluconic acid FT reductase (EC 1.1.1.-) (277 aa), fasta scores opt: 1006 FT z-score: 1188.8 E(): 0 52.9% identity in 274 aa overlap and FT Streptomyces coelicolor TR:Q9ZBW7(EMBL:AL034443;) putative FT oxidoreductase, SC4B5.01C (277 aa), fasta scores opt: 1018 FT z-score: 1202.9 E():0 56.3% identity in 268 aa overlap. FT Contains Prosite hits to PS00063 Aldo/keto reductase family FT putative active site signature, PS00062 Aldo/keto reductase FT family signature 2 and PS00798 Aldo/keto reductase family FT signature 1. Also contains a Pfam match to entry PF00248 FT aldo_ket_red, Aldo/keto reductase family." FT /db_xref="GOA:Q9KYM9" FT /db_xref="HSSP:1HW6" FT /db_xref="InterPro:IPR020471" FT /db_xref="UniProtKB/TrEMBL:Q9KYM9" FT /protein_id="CAB92199.1" FT /translation="MISIPAYTLNDGTSLPALGLGTWPMKDEEAERAVRAALETGYRLI FT DTATNYRNETGVGRGVASAGLPREEIVVTTKLPGRHHGYEETLASFEESRARLGLEYVD FT LYLIHWPLPRVDKYVDSWKAMVKLREDGLVRSVGVSNFTAEHIERLERETGVLPSVNQI FT ELHPLLPQDELRAYHERKGIRTESWSPLGRGSDLLDDPAVAAVAAAHGVTPAQAVLRWH FT TQLGAVPIPKSADPARQRANLDVFGFELDAEQLRAVADRVHRRIGGDPEVHEEF" FT misc_feature complement(106820..107566) FT /note="Pfam match to entry PF00248 aldo_ket_red, Aldo/keto FT reductase family, score 413.30, E-value 3.8e-121" FT misc_feature complement(106856..106903) FT /note="PS00063 Aldo/keto reductase family putative active FT site signature" FT misc_feature complement(107165..107218) FT /note="PS00062 Aldo/keto reductase family signature 2" FT misc_feature complement(107417..107470) FT /note="PS00798 Aldo/keto reductase family signature 1" FT CDS 107703..108689 FT /transl_table=11 FT /gene="SCO7357" FT /gene_synonym="SC9H11.11" FT /product="probable dioxygenase." FT /note="SC9H11.11, probable dioxygenase, len: 328 aa. Highly FT similar to many including: Escherichia coli FT SW:TAUD_ECOLI(EMBL:D85613) alpha-ketoglutarate-dependent FT taurine dioxygenase (EC 1.14.-.-) (282 aa), fasta scores FT opt: 462 z-score: 559.5 E(): 1.1e-23 35.0% identity in 294 FT aa overlap and Mycobacterium tuberculosis FT SW:YY06_MYCTU(EMBL:Z77165) putative dioxygenase RV3406 (EC FT 1.-.-.-) (295 aa), fasta scores opt: 523 z-score: 632.3 FT E(): 9.3e-28 41.6% identity in 308 aa overlap." FT /db_xref="GOA:Q9KYM8" FT /db_xref="HSSP:1GY9" FT /db_xref="InterPro:IPR003819" FT /db_xref="UniProtKB/TrEMBL:Q9KYM8" FT /protein_id="CAB92200.1" FT /translation="MTTDSARDSARDTATDGTTGIEVEPVAGHIGAEIRGVDLAAGLDA FT AQVAAVRSAVLRWKVVFFRDQRLDHAGHVAFARLFGEPVVLPRRGKASPAGFPEIETTA FT DRLELGGRFGMEHDEWLRRRRHTLLRGWHCDHGARVDPPAATVLRAETVPPYGGDTTWA FT NLAAAYAGLSAPLRALVDTLRAEHRLGVGYQPRPGDDAYVRHLLHHQTATVHPLVRVHP FT ETGERVLFVNGYYVEQIAGLSRPESAAILELLVEQATRPEYTVRFRWEPGSVAFWDNRA FT TIHLAPGDHAHLDHPRTMHRVMLTGDVPVGVDGTPSEPVVGSEAGRW" FT CDS complement(108720..110222) FT /transl_table=11 FT /gene="SCO7358" FT /gene_synonym="SC9H11.12c." FT /product="hypothetical protein SC9H11.12c." FT /note="SC9H11.12c, unknown, len: 500 aa." FT /db_xref="UniProtKB/TrEMBL:Q9KYM7" FT /protein_id="CAB92201.1" FT /translation="MSNSSRDSAEGAGWGSAEPGAYRALMPGRTEKLSWLSPRTLWAAR FT NGVLASWFGDPTGRTRSRWVAQRAAAGAPADKVIGRDDPDRFSFLVIGDTGEGDDPQYA FT VVPGLLEAGRDTRFAVLASDVIYPVGSADDYGTKFFRPYRDYRAPIYAIPGNHDWYEDL FT GAFMRVFCDDAPPLAPEAAPRRFTRAWLRSLLWHRPRPEDGARLAEARELRPAPSQQAA FT QPGPYWAVDAGPVRIVGIDTGLLGTVDAEQGAWLREVSAGDRPKILVTGSPLYVDGEHH FT PCEIEGGGTVDDIVRDPAHHYVAAIGGDIHNYQRYPVDVDGRTVQYVVAGGGGAFMHAT FT HTIPRVSVAGVTEDDFRSYPLRGDSLAFYSALYGRRLRMRRLFTLTEAEATAVIAERLG FT IRTGRAPGDGARVTRRTRIVAGLLGTARRPERRKRFRLPVRKIYTSVFSPGSATYSPPF FT FKCFLRLDVTPEAVRLRCYAATGNRAQEVDPPVEDEVTIPLG" FT CDS complement(110314..111069) FT /transl_table=11 FT /gene="SCO7359" FT /gene_synonym="SC9H11.13c" FT /product="putative hydrolase." FT /note="SC9H11.13c, possible hydrolase, len: 251 aa. Weakly FT similar to several members of the Dienelactone hydrolase FT family e.g. Pseudomonas putida SW:CLCD_PSEPU(EMBL:M16964) FT carboxymethylenebutenolidase (EC 3.1.1.45) (246 aa), fasta FT scores opt: 265 z-score: 312.9 E(): 5.7e-10 27.1% FT identity in 255 aa overlap and Mycobacterium tuberculosis FT TR:O33307(EMBL:AL008967) hypothetical 26.2 kd protein (245 FT aa), fasta scores opt: 630 z-score: 731.0 E(): 0 43.1% FT identity in 246 aa overlap. Contains a Pfam match to entry FT PF01738 DLH, Dienelactone hydrolase family." FT /db_xref="GOA:Q9KYM6" FT /db_xref="InterPro:IPR002925" FT /db_xref="UniProtKB/TrEMBL:Q9KYM6" FT /protein_id="CAB92202.1" FT /translation="MTATAGTALDIPTGDGTADAYLTRPADGGPHPAVLLYMDAFGLRP FT SLRSMADRLAGAGYTVLVPNVFYRSGRTPVVELPGFIDPRARPEIFERLGPIMRSLTPD FT LAMRDADAYLRLLAGRPEAADGPVALVGYCMGAALALRTAGTYPDRVAAVAGFHGANLA FT TDGPHSPHLVAGDITAEAYFAHADQDPGMDAEQQERLSAALTAAGVRHRCEVYAGAHHG FT YTQADTSAYDPEATERHWTALLDLLKRTF" FT misc_feature complement(110501..117037) FT /note="shares 99.76% sequence identity, over 6539 bases, FT with Streptomyces coelicolor EMBL:AB017438 orf1, orf2, FT orf3, orf4, orf5 genes, complete cds. A region involved in FT the multicopy suppression of afsR mutants." FT CDS complement(111119..111721) FT /transl_table=11 FT /gene="SCO7360" FT /gene_synonym="SC9H11.14c" FT /product="conserved hypothetical protein SC9H11.14c." FT /note="SC9H11.14c, unknown, len: 200 aa. Previously FT sequenced: Streptomyces coelicolor FT TR:BAA82702(EMBL:AB017438) Orf5 (200 aa). Also similar to FT many other proteins of undefined function e.g. Neisseria FT meningitidis TR:AAF40874(EMBL:AE002400) conserved FT hypothetical protein (213 aa), fasta scores opt: 821 FT z-score: 1024.7 E(): 0 56.8% identity in 199 aa overlap. FT Contains a Prosite hit to PS01147 SUA5/yciO/yrdC family FT signature and a Pfam match to entry PF01300 Sua5_yciO_yrdC, FT SUA5/yciO/yrdC family. Contains a putative helix-turn-helix FT motif situated between residues." FT /db_xref="HSSP:1K7J" FT /db_xref="InterPro:IPR006070" FT /db_xref="UniProtKB/TrEMBL:Q9KYM5" FT /protein_id="CAB92203.1" FT /translation="MHPDNPQPRSIAQVADSVRSGALIAYPTDSCYALGCRLGSRDGID FT RIRSIRQLDNRHHFTLVCQDFAQLGQFVQIDNDVFRAIKASTPGSYTFILPATREVPRA FT LQHPKKKTVGVRIPDHVVTQALLAELGEPLLSSTLLLPDEEEPMTQGWEIKDRLDHVLD FT AVVDSGDCGTEPTTVVDFSGGEAEIVRHGAGDTTRFE" FT misc_feature complement(111146..111676) FT /note="Pfam match to entry PF01300 Sua5_yciO_yrdC, FT SUA5/yciO/yrdC family, score 162.40, E-value 7.4e-45" FT misc_feature complement(111617..111655) FT /note="PS01147 SUA5/yciO/yrdC family signature" FT RBS 111873..111878 FT CDS 111887..113416 FT /transl_table=11 FT /gene="SCO7361" FT /gene_synonym="SC9H11.15." FT /product="putative DNA-binding protein" FT /note="SC9H11.15, possible DNA-binding protein, len: 509 FT aa. Previously sequenced: Streptomyces coelicolor FT TR:BAA82701 (EMBL:AB017438) Orf4 (509). Contains a putative FT helix-turn-helix motif situated between residues 439..460 FT (+3.90 SD)." FT /db_xref="GOA:Q9S5E5" FT /db_xref="UniProtKB/TrEMBL:Q9S5E5" FT /protein_id="CAB92204.1" FT /translation="MAGRQDGGRQRTSGAGEPAGWAQELLDHLRPAGRDLNRVVAWLAG FT IARAAVALQDDTGRLLAGTRVPLDDVLVADLTSGRIASAALEDRGRHLRLVRVERSRPA FT PAAVLAVAREEPFDRRVSDIVTHAAQVLELLLAGHESTAAGHRLRRATSDLRLAILQLL FT MVEDTVSARRVAAGLWPGLLDTDTACVYVVESSPAERDRLAEECLSATGERALVVRCPA FT VDGHVIVLAPRDTAGQELRTLVGRRPGVFVGGSARQGLARTAAAYGQAVSALAVARFRP FT EKAALYAERTRPERLMDPAALHDWTADVLSPLDRLSHHTRAELIATTRLGLEFTAVNAA FT KVLGVSRNTVRARMDRVESLLRTDFADLTVRAAVHLALNAQVGLAEPPPGAGARAGAAR FT LTDLLAGPALRTWAVDLLGRLDPDGRDLRRTLRTWIAAGGNAERAAQQLGMHAQTVREH FT VRSAEPVLERQLLAAGSDLYEVVLAHLAAGDLGQPLLHGTKPGHPDSPVHE" FT CDS complement(113571..114611) FT /transl_table=11 FT /gene="SCO7362" FT /gene_synonym="SC9H11.16c." FT /product="oxidoreductase." FT /note="SC9H11.16c, oxidoreductase, len: 346 aa. Previously FT sequenced: Streptomyces coelicolor FT TR:BAA82700EMBL:AB017438) Orf3 (346 aa). Also highly FT similar to Corynebacterium sp. ST-10 FT TR:Q9ZN85(EMBL:AB020760) phenylacetaldehyde reductase (385 FT aa), fasta scores opt: 1382 z-score: 1438.5 E(): 0 65.2% FT identity in 316 aa overlap and many alcohol dehydrogenases FT e.g. from Sulfolobus solfataricus FT SW:ADH1_SULSO(EMBL:S51211) NAD-dependent alcohol FT dehydrogenase (EC 1.1.1.1) (347 aa), fasta scores opt: 595 FT z-score: 624.4 E(): 2.5e-27 32.7% identity in 355 aa FT overlap. Contains a Prosite hit to PS00059 Zinc-containing FT alcohol dehydrogenases signature and a Pfam match to entry FT PF00107 adh_zinc, Zinc-binding dehydrogenases." FT /db_xref="GOA:Q9S5E6" FT /db_xref="HSSP:1H2B" FT /db_xref="InterPro:IPR013154" FT /db_xref="UniProtKB/TrEMBL:Q9S5E6" FT /protein_id="CAB92205.1" FT /translation="MKALQYRTIGAPPEVVTVPDPEPGPGQVLLKVTAAGVCHSDIAVM FT SWPAEGFPYELPLTLGHEGVGTVAALGAGVTGLAEGDAVAVYGPWGCGTCAKCAEGKEN FT YCLRADELGIRPPGLGRPGSMAEYLLIDDPRHLVPLDGLDPVAAVPLTDAGLTPYHAIK FT RSLPKLVPGSTAVVIGTGGLGHVAIQLLRALTSARVVALDVSEEKLRLARAVGAHEAVL FT SDAKAADAVREITGGLGAEAVFDFVGVAPTVQTAGAVAAVEGDVTLVGIGGGSLPVGFG FT MLPFEVSVNAPYWGSRSELTEVLNLARSGAVSVHTETYSLDDAPLAYERLHEGRVNGRA FT VILPHG" FT misc_feature complement(113583..114596) FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score 222.80, E-value 4.9e-63" FT misc_feature complement(114387..114431) FT /note="PS00059 Zinc-containing alcohol dehydrogenases FT signature" FT CDS complement(114680..115471) FT /transl_table=11 FT /gene="SCO7363" FT /gene_synonym="SC9H11.17c." FT /product="putative oxidoreductase." FT /note="SC9H11.17c, possible oxidoreductase, len: 263 aa. FT Almost identical to the previously sequenced: Streptomyces FT coelicolor TR:BAA82699EMBL:AB017438) Orf2 (263 aa). Also FT highly similar to Pseudomonas paucimobilis FT SW:LINC_PSEPA(EMBL:D14595) FT 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase (EC FT 1.1.-.-) LinC (250 aa), fasta scores opt: 580 z-score: FT 605.0 E(): 3.1e-26 42.5% identity in 252 aa overlap and FT Streptomyces coelicolor TR:O88068(EMBL:AL031541) putative FT dehydrogenase, SCI35.33C (260 aa), fasta scores opt: 584 FT z-score: 608.8 E(): 1.9e-2 43.8% identity in 251 aa FT overlap. Contains a Prosite hit to PS00061 Short-chain FT dehydrogenases/reductases family signature and Pfam matches FT to entries PF00106 adh_short, short chain dehydrogenase and FT PF00678 adh_short_C2, Short chain dehydrogenase/reductase FT C-terminus." FT /db_xref="GOA:Q9KYM4" FT /db_xref="HSSP:1GZ6" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9KYM4" FT /protein_id="CAB92206.1" FT /translation="MSTTGTTPATTGYAAEFAGRTALVTGAASGIGLATARRLGAGGAR FT VVVADFNAEGAEKAAAELRAGGVEAAAVELDVTRPESVEAAVGFAVDTFGSLDLAVNNA FT GIGGPSAPTGEYDVAAYQRVVRTNLDGVFYSMRYELPAIEAAGKGGSIVNVASILGSVG FT FAGSPAYVAAKHGVVGLTKAAAAEYAARGIRINAVGPGFIDTPLLKTMDEAAYKGLVAL FT HPAGRLGRSEEVAELIAFLLSDRASFVAGSYHLVDGAYTAV" FT misc_feature complement(114704..114796) FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 30.80, FT E-value 5e-07" FT misc_feature complement(114854..115414) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 230.70, E-value 2.1e-65" FT misc_feature complement(114917..115003) FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT CDS complement(115482..116186) FT /transl_table=11 FT /gene="SCO7364" FT /gene_synonym="SC9H11.18c" FT /product="putative TetR-family transcriptional regulator." FT /note="SC9H11.18c, possible TetR-family transcriptional FT regulator, len: 221 aa. Previously sequenced: Streptomyces FT coelicolor TR:BAA82698 (EMBL:AB017438) Orf1 (187 aa). FT Differs with the previously published sequence in the FT C-terminus, possibly due to a frameshift in the original FT sequence. Similar to several e.g. Streptomyces glaucescens FT SW:TCMR_STRGA (EMBL:M80674) tetracenomycin C FT transcriptional repressor, TcmR (226 aa), fasta scores opt: FT 338 z-score: 403.7 E(): 5e-15 37.3% identity in 217 aa FT overlap. Contains a Pfam match to entry PF00440 tetR, FT Bacterial regulatory proteins, tetR family with the FT putative helix-turn-helix motif situated between residues FT 54..75 (+4.96 SD)." FT /db_xref="GOA:Q9KYM3" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9KYM3" FT /protein_id="CAB92207.1" FT /translation="MSHWDIFRCTLEDMTATKPSPATEDRRQRKARQTRDALATAACDL FT ILEHGPAATTVEAIAERADVTRRTFSRHFAGKEDAALDFVRRDGDRINALLRSRPAGEP FT PLLAYRRAVREWLADREDPAWHVRPRMRRLLALADTEPELFAAYQRIRVDAQEESIRIV FT AARLGSDDVRDVRPAAVVDAAAGVLIAALRLWARGGEGDSAAADLAALVEQAYDALTSE FT AAAATPESTTEE" FT misc_feature complement(115935..116075) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 38.30, E-value FT 6.6e-09" FT RBS 116278..116281 FT CDS 116292..116615 FT /transl_table=11 FT /gene="SCO7365" FT /gene_synonym="SC9H11.19" FT /product="hypothetical protein SC9H11.19." FT /note="SC9H11.19, unknown, len: 107 aa." FT /db_xref="UniProtKB/TrEMBL:Q9KYM2" FT /protein_id="CAB92208.1" FT /translation="MTSSAFHRTIVLPAPVCRQAAQHLEQAVHKAIDGAATPWRAFRGA FT DGDDFAFSVPVVEQAAGCLLVLAAESAQSLRPSALRALISVALHLRDAAEAVRRPAVPS FT PAW" FT CDS 116701..117468 FT /transl_table=11 FT /gene="SCO7366" FT /gene_synonym="SC9H11.20" FT /product="conserved hypothetical protein SC9H11.20." FT /note="SC9H11.20, unknown, len: 225 aa. Similar to FT Streptomyces coelicolor TR:O86750(EMBL:AL031035) FT hypothetical 28.3 kd protein, SC6A9.18C (266 aa), fasta FT scores opt: 304 z-score: 354.9 E(): 2.6e-12 32.8% identity FT in 253 aa overlap." FT /db_xref="InterPro:IPR010872" FT /db_xref="UniProtKB/TrEMBL:Q9KYM1" FT /protein_id="CAB92209.1" FT /translation="MEFTRFLDCLATDHDRLRDVVETDPDAPVPTCPGWTVADLTRHVG FT EVYLHKAAAMRDGAEPEPWPPEEFADEAPTKLLDRGYAALRAEFAARAPEDPAGTWYGP FT DQSVGFWIRRMAQETVVHRIDAELATGRPVDAVPDDLAVDGVDELLKVFAAYSVAEWGD FT YFTEILDGSPGRTFLVRAGDHAAWRVRTGPGEFTVTDGAGDGTADATLSGPPESVLRSL FT WNRAGADGDRGVTVEGDLGALAELRRCIVVATQ" FT CDS complement(117502..118842) FT /transl_table=11 FT /gene="SCO7367" FT /gene_synonym="SC9H11.21c" FT /product="probable membrane efflux protein." FT /note="SC9H11.21c, probable membrane efflux protein, len: FT 446 aa. Similar to many proteins involved in arsenical FT resistance e.g. Staphylococcus xylosus FT SW:ARSB_STAXY(EMBL:M80565) arsenical pump membrane protein FT ArsB (429 aa), fasta scores opt: 255 z-score: 240.6 E(): FT 6.1e-06 24.1% identity in 440 aa overlap and Mycobacterium FT tuberculosis TR:P96860(EMBL:Z92774) probable arsenical pump FT membrane protein (413 aa), fasta scores opt: 730 z-score: FT 667.0 E(): 1.1e-29 53.7% identity in 445 aa overlap. FT Contains possible N-terminal region signal sequence peptide FT and multiple possible membrane spanning hydrophobic FT domains." FT /db_xref="GOA:Q9KYM0" FT /db_xref="InterPro:IPR000802" FT /db_xref="UniProtKB/TrEMBL:Q9KYM0" FT /protein_id="CAB92210.1" FT /translation="MPVVLLLGVLAFAVLRPRGLPEAVAAVPAAVLVVALGMVSPHRAW FT EQTRTLLPVVVFLALVLMLAYLCAKEGLFEAVGAAVARRCGGSPRRLLTGVFAVACAVT FT AVLSLDATAVLLTPVVLATASRAGARARPHVYATAHLANSASLLLPVSNLTNLLAFTAS FT GLSFTRFAALMALPWLAAIAVEYAVFRRFFRTDLAEPVSAAPARVGSVSVAPGPSGPAG FT PAPAKARGGAPGAGPGVASAPPAPAVPRFTVVVVALTLAGFAVASPAGVDPAWAALGGV FT LVLGARALARRHVTPREMAGAAAPLFCLFVLALGIVVQGVLAGASATGLGRLLPDGDSL FT PALLGVAAVAAVLANVVNNLPAVLALLPLAAPAGPAQVLAVLIGVNLGPNLTYVGSLAT FT LLWRRILHRHGIEVELGRFTALGLLTVPATVAASTVALWGALRLVGT" FT CDS 119049..119612 FT /transl_table=11 FT /gene="SCO7368" FT /gene_synonym="SC9H11.22" FT /product="hypothetical protein SC9H11.22." FT /note="SC9H11.22, unknown, len: 187 aa." FT /db_xref="UniProtKB/TrEMBL:Q9KYL9" FT /protein_id="CAB92211.1" FT /translation="MFPTTSSSDGPAVHTDLSPVIAATAQWLTRAYPASGGALAGALCE FT AQARQAVTVAARLRYPTPMDVALLGVAGPGGSARLDRITGADGATPTDPDADAWRTWVD FT EVVASWAACLLSDPALAGPAVAALAEGGPSAGTPAEFRRLLAPGDADRRAAALLRHPDL FT VAPVAVLHHAGLLARLDPGRALVA" FT CDS complement(119660..120973) FT /transl_table=11 FT /gene="SCO7369" FT /gene_synonym="SC9H11.23c" FT /product="putative transmembrane transport protein." FT /note="SC9H11.23c, possible transmembrane transport FT protein, len: 406 aa. Similar to many putative membrane FT transport proteins e.g. Zymomonas mobilis FT TR:Q9XBR9(EMBL:AF157493) putative transporter, DitE (431 FT aa), fasta scores opt: 499 z-score: 512.6 E(): 4.3e-21 FT 26.3% identity in 407 aa overlap. Contains multiple FT possible membrane spanning hydrophobic domains." FT /db_xref="GOA:Q9KYL8" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9KYL8" FT /protein_id="CAB92212.1" FT /translation="MSSSPVSAPPSPAAPPSEPSRSPWRSLRHRSMRWWSVANFVSNAG FT TWMQLTVQNLLVLQITGSAAATGLSMSVQAAPALLISVFGGAAVDRWPRKLTAAVSQAL FT LGAVAFVTALMVALDRLDMGSLMVLAAVTGVIATVDGPACSLLGNDLVPREDVPSAIGV FT GALVHQAGRLTGAALAGVTVGFLGTAAAYAANGLSFLFVASVIPFLRPARGAIRHAGAA FT EERGAQDTMSVREGLTFFARRPRLLALAGVTGVSAVFGRNYQLTLAVLVTGPLAGGAGS FT FGTVSTVLAVGGIVGAVLGARLRRPSVRVVGALAAAGGLLQVVAGLSPSLAVLLVMVLP FT MAVVESVSDTAGTAVLQTDPPAHMRGRVLGVWGSIGTVWGLGGPPALGLLMELAGARGA FT LIAGGLVIAGTIGAGHLLRERRAAVPRVSPVANLETAA" FT CDS 121344..122384 FT /transl_table=11 FT /gene="SCO7370" FT /gene_synonym="SC9H11.24" FT /product="NAD-dependent dehydratase." FT /note="SC9H11.24, NAD-dependent dehydratase, len: 346 aa. FT Similar to many members of the sugar epimerase/dehydratase FT family including: Streptomyces griseus FT SW:STRE_STRGR(EMBL:X62567) DTDP-glucose 4,6-dehydratase (EC FT 4.2.1.46) (328 aa), fasta scores opt: 363 z-score: 378.8 FT E(): 1.2e-13 31.8% identity in 336 aa overlap and FT Streptomyces coelicolor TR:Q9ZBN0 (EMBL:AL034492) putative FT nucleotide-sugar dehydratase, SC6C5.15 (330 aa), fasta FT scores opt: 977 z-score: 1003.9 E(): 0 52.6% identity in FT 321 aa overlap. Contains a Pfam match to entry PF01370 FT Epimerase, NAD dependent epimerase/dehydratase family." FT /db_xref="GOA:Q9KYL7" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9KYL7" FT /protein_id="CAB92213.1" FT /translation="MMPMAAFSPRGESRTPWGRVLVTGGAGFLGSHLCTRLLDAGAEVD FT CLDNLSTGRAEKVAHLAGRPGFRFLERDISAPGCADALTGPYDLVLHLAGPASPAARPD FT RPVEALDAGSLGTRTALSVAGRDGARFLLASSPPAGPGTRGDAPDDADPVGPHRACAEA FT VRFAEALVAAHAGANGSNAGIVRLFDGYGPGMRTDGAGTPAALIEAALTGRPVTVPGDG FT SGTYPLCYVDDMVDGVLLVAAGRSVRPVDIGGDEEPTAAEIARLVIELTGSDSPLAFVE FT DAGDGRPRPRPVTGFAREIFGWLPSVAWQDGLERTVAAFRDRPDPVPTATREPAGERMG FT EWWAQG" FT misc_feature 121401..122315 FT /note="Pfam match to entry PF01370 Epimerase, NAD dependent FT epimerase/dehydratase family, score 1.70, E-value 2.4e-12" FT stem_loop 122430..122501 FT /note="possible stem loop with 94% matches over 36 bases." FT CDS complement(122508..123071) FT /transl_table=11 FT /gene="SCO7371" FT /gene_synonym="SC9H11.25c" FT /product="hypothetical protein SC9H11.25c." FT /note="SC9H11.25c, unknown, len: 187 aa. Weakly similar to FT proteins of unknown function from: Schizosaccharomyces FT pombe (Fission yeast) TR:CAB60016 (EMBL:AL132779) (203 aa), FT fasta scores opt: 275 z-score: 313.3 E(): 5.4e-10 25.7% FT identity in 175 aa overlap and Streptomyces coelicolor FT TR:CAB53436(EMBL:AL109989) SCJ12.24C (157 aa), fasta scores FT opt: 139 z-score: 166.4 E(): 0.082 27.0% identity in 122 FT aa overlap." FT /db_xref="InterPro:IPR012312" FT /db_xref="UniProtKB/TrEMBL:Q9KYL6" FT /protein_id="CAB92214.1" FT /translation="MGHGGNVIDELTTDHREVEELFGKIEALPPGHKDRKLYADQATIE FT LVRHSVAEEAYLYPAVREHVPGGGALADKELEDHAGAEQIMKDLEGCAADDAEFDRLIG FT KLMSEIREHVADEEGNLFPRLREACPADALDELGEKVRRAKKTAPTRPHPAAPDKPPMD FT KLLAPGAGMVDRVRDALSGRGRSG" FT RBS complement(123076..123082) FT CDS complement(123152..123685) FT /transl_table=11 FT /gene="SCO7372" FT /gene_synonym="SC9H11.26c" FT /product="hypothetical protein SC9H11.26c." FT /note="SC9H11.26c, unknown, len: 177 aa." FT /db_xref="InterPro:IPR011637" FT /db_xref="UniProtKB/TrEMBL:Q9KYL5" FT /protein_id="CAB92215.1" FT /translation="MSLLRLAGRPMLASMFVAGGLQSLRRPQDVAPAAEPVVRPVADRV FT PVLPDSTEQLVRLNGAVHVVGGIMLGLGRCPRLAALALAVTLVPTTLAAHRYWEAEDPS FT DRAQQRIHFLKNLSMMGGLLIAADDTGSAPSLLWRGRHAAHDLRHDAHLVHRSVRAAAG FT PAARAGGVRARLGA" FT CDS complement(123841..124332) FT /transl_table=11 FT /gene="SCO7373" FT /gene_synonym="SC9H11.27c" FT /product="hypothetical protein SC9H11.27c." FT /note="SC9H11.27c, unknown, len: 163 aa." FT /db_xref="UniProtKB/TrEMBL:Q9KYL4" FT /protein_id="CAB92216.1" FT /translation="MNGIDLTLRTLHRGERHLAHDLVTVAERHRTEHEVHHVATDLARW FT SREHMRQLAETAAERGAKLGEPPGHSADGVFATLREKASEAVAHRPEPGLLLLRDLREL FT HVLAAENSLHWEMLAQAAQASRDSALLTLASSCHPRTLRQMRWTNTMIKNLAPQILTSL FT " FT CDS complement(124329..126821) FT /transl_table=11 FT /gene="SCO7374" FT /gene_synonym="SC10G8.01c" FT /gene_synonym="narB" FT /product="putative oxidoreductase" FT /product="nitrate reductase NarB (fragment)" FT /note="SC10G8.01c, possible oxidoreductase, partial CDS, FT len: > 355 aa. Similar to many e.g. Paracoccus FT denitrificans SW:NAPA_PARDT (EMBL:Z36773) periplasmic FT nitrate reductase precursor (EC 1.7.99.4) (831 aa), fasta FT scores opt: 550 z-score: 651.4 E(): 7.2e-29 33.1% identity FT in 317 aa overlap." FT /note="SC9H11.28c, narB, nitrate reductase (EC 1.7.99.4), FT partial CDS, len: > 508 aa. Highly similar to many FT including: Synechocystis sp. (strain PCC 7942) FT SW:NARB_SYNP7 (EMBL:X74597) nitrate reductase (EC FT 1.7.99.4), NarB (729 aa), fasta scores opt: 583 z-score: FT 613.8 E(): 1e-26 36.1% identity in 457 aa overlap and FT Oscillatoria chalybea TR:Q51328 (EMBL:X89445) nitrate FT reductase (EC 1.7.99.4), NarB (737 aa), fasta scores opt: FT 610 z-score: 642.1 E(): 2.6e-28 35.7% identity in 460 aa FT overlap. Contains a Prosite hit to PS00490 Prokaryotic FT molybdopterin oxidoreductases signature 2 and Pfam matches FT to entries PF00384 molybdopterin, Prokaryotic molybdopterin FT oxidoreductases and PF01568 Molydop_binding, Molydopterin FT dinucleotide binding domain." FT /db_xref="GOA:Q8CJK2" FT /db_xref="HSSP:2NAP" FT /db_xref="InterPro:IPR006657" FT /db_xref="UniProtKB/TrEMBL:Q8CJK2" FT /protein_id="CAD55398.1" FT /translation="MEDATDRIARPWGARVPYGRHETWPARVDTFLAEGVEPEAVQRWV FT QSASILHSDGDAMDIAVADGRMVGVRGRDVDRVNRGRLGPKDLFGWQANASRDRLTRPL FT VRRDGQLVETDWDTAMDLVAARSRELLDSRGPGSIGFYTSGQLFLEEYYTLAVLARAGI FT GTNHLDGNTRLCTSTAAEALKESFGCDGQPGSYDDFDHADVIALFGHNIAETQPVQWMR FT LLDRLEGADPPRLLCVDPRPTRVAEHAAVHLAPRSGTNVALLNALLHETIRHERIDRDF FT IDAHTVGFGELAARVADCTPKWAAEICDVPAARIEEAAELVGTAEALVSTVLQGVYQSH FT QATAAAVQVNNLHLIRGMLGRPGAGLLQMNGQPTAQNTRECGANGDLPGFRNWQNDAHV FT ADLARVWNVEPETIPHFAPPTHAMQIFRYAEQGSLRMLWISGTNPAVSMPELPRIRSIL FT SQERLFTVVQDLYLTETARLADVVLPAATWGEKTGALTNADRTVHLSRKAVEPPGEARP FT DLDIFLDYARRMDFRDKDGGPLIPWDGPESAFEAWKRCSAGRPCDYTGLSYAKLRDTSG FT IQWPCDDRAPEGTARLYTDGFGWAHPDVCESYGKDLETGASQEVVEYRSLNPDGRAMLK FT AAAYLPPHEEPDEEYPFQLTTGRTLYHFHTRTKTGRAPQLNDAAPDVWVEVSAGDAERL FT GLGEGDLVEVTSRRGSLRGRLRVTGIRTGLLFVPFHYGYWDTAGGSGPGPDTPGRAANE FT TTVTDWDPASKQPLFKTAAAALTLVERGGGRPSPAPTTTASAPVTAGAAPPTSGGPAAR FT TTEREPTEFPHGREEGAR" FT misc_feature complement(124506..124868) FT /note="Pfam match to entry PF01568 Molydop_binding, FT Molydopterin dinucleotide binding domain, score 96.40, FT E-value 5.5e-25" FT misc_feature complement(125244..125432) FT /note="Pfam match to entry PF00384 molybdopterin, FT Prokaryotic molybdopterin oxidoreductases, score 98.90, FT E-value 2.6e-31" FT misc_feature complement(125352..125405) FT /note="PS00490 Prokaryotic molybdopterin oxidoreductases FT signature 2" FT RBS complement(126828..126832) FT CDS 126898..127692 FT /transl_table=11 FT /gene="SCO7375" FT /gene_synonym="SC10G8.02" FT /product="putative acetyltransferase." FT /note="SC10G8.02, possible acetyltransferase, len: 264 aa. FT Similar to Deinococcus radiodurans FT TR:AAF12253(EMBL:AE001862) putative acetyltransferase (210 FT aa), fasta scores opt: 272 z-score: 314.3 E(): 4.3e-10 FT 30.9% identity in 207 aa overlap. Contains a Pfam match to FT entry PF00583 Acetyltransf, Acetyltransferase (GNAT) FT family. Contains a 7xDT repeat region in the C-terminus." FT /db_xref="GOA:Q9L1A0" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9L1A0" FT /protein_id="CAB76276.1" FT /translation="MGALPGGQHAEVTATASVRPYRPADAPALDDICIRTAHNGRDSRP FT VYADPAVLPAIFAAPYVHLDPGLAFVLDDGRGRAVGYILGTADTARFAAEFRATWLPRV FT ADRYPAPQGPPGTRTPDEVMAGLLHDPERMVVPELAAYPAHLHIDLLPDWQGRGHGRTL FT MRTLWRALRERGVPAVHLVMATANTPARAFYDRLGFHEVPASGLDPAEVTCLGRTTQDT FT EDMEGTEDTEGTQGAEDTHDTENTRGTEDTHDTHDTRGTERT" FT misc_feature 126949..127497 FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 24.10, E-value FT 0.0032" FT repeat_region 127557..127671 FT /note="repeat region containing 12x GGA and 3x GCACGAC FT repeats." FT CDS complement(127725..128453) FT /transl_table=11 FT /gene="SCO7376" FT /gene_synonym="SC10G8.03c" FT /product="conserved hypothetical protein SC10G8.03c" FT /note="SC10G8.03c, unknown, len: 242 aa. Weakly similar to FT Aeropyrum pernix TR:Q9Y911 (EMBL:AP000064) hypothetical FT protein (205 aa), fasta scores opt: 226 z-score: 263.2 E(): FT 3e-07 31.8% identity in 211 aa overlap and to TR:CAC48481 FT (EMBL:AL603642) Rhizobium meliloti (Sinorhizobium meliloti) FT conserved hypothetical protein SMB20081, 236 aa; fasta FT scores: opt: 577 Z-score: 646.5 E(): 2.2e-28; 46.256% FT identity in 227 aa overlap" FT /db_xref="GOA:Q9L199" FT /db_xref="InterPro:IPR004843" FT /db_xref="UniProtKB/TrEMBL:Q9L199" FT /protein_id="CAB76277.1" FT /translation="MTIRVAAVGDIHMGPDSEGLLRPAFETLPDCADMLLLAGDLTRHG FT TPREARVVAREVRDLPVPVVAVLGNHDHHDERPEEVTAILRDAGVTVLEGEATVVECAG FT GRVGIAGTKGFGGGFVGRSAGEFGEPVMKEFVRTTRRSADSLHAALKQLAEEDCAARVA FT LTHFSPVADTLAGEPPEIHPFLGSYLLAEAIDTAGADLAVHGHAHLGTEHGMTAGGVRV FT RNVAQPVIRRAFNVYRLDGD" FT CDS complement(128450..128707) FT /transl_table=11 FT /gene="SCO7377" FT /gene_synonym="SC10G8.04c" FT /product="hypothetical protein SC10G8.04c." FT /note="SC10G8.04c, unknown, len: 85 aa." FT /db_xref="InterPro:IPR000886" FT /db_xref="UniProtKB/TrEMBL:Q9L198" FT /protein_id="CAB76278.1" FT /translation="MSDPGVQNVEYRVAHLQDRLAAEELGELGVRAEVRAGAVALTGTV FT PSAQCRETVLRLAREELAGLTVHADVVVARTTRPDQAEEL" FT RBS complement(128458..128462) FT CDS complement(128704..129414) FT /transl_table=11 FT /gene="SCO7378" FT /gene_synonym="SC10G8.05c" FT /product="hypothetical protein SC10G8.05c." FT /note="SC10G8.05c, unknown, len: 236 aa." FT /db_xref="UniProtKB/TrEMBL:Q9L197" FT /protein_id="CAB76279.1" FT /translation="MRQPADDQATGRRAGVSELRPADGDRGPALRREAPHEDLPLDRNQ FT AILQAAKQVGSTLKKAEHPFALAGSVAVYAHGGTQNLQHDVDFCIRPEDADAVAATLRE FT AGLTVYTPPEDWLLKADCLGQQVDLIFELAHEPVTTALLDRARDLSVDSVLMPVLSPTD FT LLRGLLAAFSEHHCDFGAVLPIARTLREKIDWAALRRDCGDDPMPAAFFFVLERLEIIP FT PAGPPATASKEDQR" FT CDS 129562..129873 FT /transl_table=11 FT /gene="SCO7379" FT /gene_synonym="SC10G8.06" FT /product="hypothetical protein SC10G8.06." FT /note="SC10G8.06, unknown, len: 103 aa." FT /db_xref="UniProtKB/TrEMBL:Q9L196" FT /protein_id="CAB76280.1" FT /translation="MSDERMRQRTGSADRRTVERLVAAWLAETERHDPEAAGEARDGWE FT QDALSDRSAQDLATWVTARVTDTGFTEDEGPYVAGPVRITPADKDTVHAWLRARGHAV" FT CDS complement(129911..131224) FT /transl_table=11 FT /gene="SCO7380" FT /gene_synonym="SC10G8.07c" FT /product="conserved hypothetical protein" FT /note="SC10G8.07c, unknown, len: 437 aa. Similar in parts FT to several proteins of undefined function e.g. Streptomyces FT coelicolor TR:Q9ZBJ0 (EMBL:AL035161) conserved hypothetical FT protein, SC9C7.20 (860 aa), fasta scores opt: 271 z-score: FT 309.7 E(): 7.7e-10 30.3% identity in 274 aa overlap" FT /db_xref="GOA:Q9L195" FT /db_xref="InterPro:IPR001932" FT /db_xref="UniProtKB/TrEMBL:Q9L195" FT /protein_id="CAB76281.1" FT /translation="MTRAPSGGTEAPPGRTARRAGWDGRCQAAGHRSRRGGLSTGGDEV FT STSDSDDAGLRSFLADPAHLTLDLRTATARCVKALGLRHAVVYLVDLQQRHLVPQTAVA FT PSVPVDGSPAGWAYRTQSLRVEESGTGGGITAWFPLLDGAERLGVLALCETALTASSLT FT RGRALASLLAMVITSKRLYEDSFVRRTRTERMTLPAEMLRALLPPRTIGNGNVVSTAVL FT EPAYEIGGDAFDHALTETTLHVAVLDAMGHDLASGLTTTVSLAACRNARRTGADLPELV FT RSVDEALSSWLPDKFCTSVIAQLDLVTGVLRWANCGHPAPILIRDQRLVIDAMERDADP FT PMGMPSLLSPHARRTHEISLEPGDRVLMYTDGVVEARTREAKLLGLERFADYVIRATAG FT GELAPESLRRLIHSILAMQEGRLRDDATLLMFEWRPPS" FT RBS 131246..131250 FT CDS 131260..131673 FT /transl_table=11 FT /gene="SCO7381" FT /gene_synonym="SC10G8.08" FT /product="hypothetical protein SC10G8.08." FT /note="SC10G8.08, unknown, len: 137 aa." FT /db_xref="InterPro:IPR019587" FT /db_xref="UniProtKB/TrEMBL:Q9L194" FT /protein_id="CAB76282.1" FT /translation="MTEYERSRTMPAQPEQVFDQAANVGQLATWLPRDLHVEPEEPPAV FT TVHEDRTDQDTSALLSARPEQLRLEWGTREQGSYAGWLQVAGLDSGASEVTVHLSFFDD FT THDPGRRTVAEALDGSLRRLEEQVRLRTDNAAG" FT CDS complement(132036..132350) FT /transl_table=11 FT /gene="SCO7382" FT /gene_synonym="SC10G8.09c" FT /product="hypothetical protein SC10G8.09c." FT /note="SC10G8.09c, unknown, len: 104 aa. Weakly similar to FT a protein of unknown function from Streptomyces coelicolor FT TR:Q9Z548(EMBL:AL035212) hypothetical 11.6 KD protein, FT SC9B2.11 (109 aa), fasta scores opt: 101 z-score: 134.7 FT E():4.5 35.1% identity in 74 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9L193" FT /protein_id="CAB76283.1" FT /translation="MPEQGVQHGCRDGAVAVDVRLLVEEAHGFRSPHGRRGPAEQPGAR FT HGAGAVAHAVRQPDVPLDEQCRGAVHRRAVVSVHGGVDAPAPRTDTRAARGRSPGRGPP FT " FT CDS 132767..133147 FT /transl_table=11 FT /gene="SCO7383" FT /gene_synonym="SC10G8.10" FT /product="hypothetical protein SC10G8.10." FT /note="SC10G8.10, doubtful CDS, len: 126 aa." FT /db_xref="UniProtKB/TrEMBL:Q9L192" FT /protein_id="CAB76284.1" FT /translation="MDGASHGHPCRAGWLIVCSPAGVRPPRAAEVAVTRMDPERYWSRP FT NRCLLECVSGVQAGRPIMYEMCVGPEKAGGALVWHVLSKQAAATLCGQQLRERIEASDG FT ERARHCPDCMASFEKLMATTPC" FT stem_loop 133162..133200 FT /note="possible stem loop with 100 % matches over 17 bases FT and a loop of 5 bases." FT CDS 133889..135229 FT /transl_table=11 FT /gene="SCO7384" FT /gene_synonym="SC10G8.11" FT /product="putative transmembrane transport protein." FT /note="SC10G8.11, possible transmembrane transport protein, FT len: 446 aa. Similar to many other putative transporters FT including: Streptomyces coelicolor TR:O69958(EMBL:AL022268) FT putative transmembrane transport protein, SC4H2.03C (411 FT aa), fasta scores opt: 808 z-score: 828.6 E(): 0 37.9% FT identity in 414 aa overlap. Contains multiple possible FT membrane spanning hydrophobic domains and a possible FT N-terminal signal sequence." FT /db_xref="GOA:Q9L191" FT /db_xref="InterPro:IPR006153" FT /db_xref="UniProtKB/TrEMBL:Q9L191" FT /protein_id="CAB76285.1" FT /translation="MGHADTLLAMGGAFVAAAFLARLGGRIGLPTIPLFMLAGILLGPH FT TPGFVLVEDAHDFEMLSALGLVLLLFYLGLEFHLDDLRSGGKRLLTAGGIYLLLNVGAG FT LGFGFVLGWGVREALVLAGVLGISSSAIVTKILIDLGRIGRPETRLILGVIVVEDIFLA FT LYLAALQPVISGAHGVADTALQAGKAFGFLLVLAAAARYGTRLVGRLIHTRDNELLVIS FT FLGAAVLVAGVSEVLGVADAIGAFMVGLILAGTPSGPRIRELVHPLRDAFAAIFFFAFG FT LAIDPGDLASVAGPVAAAAALTVVMNIVAGLCVARVYHYGSEPAAEIATTLVARGEFAL FT ILAAMAAGAGLDAQLAPFIAGYVLVLAVLGPIVAGRAHVLAAALRAVGGLLPGTRTPVA FT AADGGAGGAETEDEDDGRPEPGPVPVPAQASPAFGSSSSPEHTEAGH" FT RBS 135371..135376 FT CDS 135385..135828 FT /transl_table=11 FT /gene="SCO7385" FT /gene_synonym="SC10G8.12" FT /product="putative integral membrane protein." FT /note="SC10G8.12, possible integral membrane protein, len: FT 147 aa. Contains possible membrane spanning hydrophobic FT domains." FT /db_xref="UniProtKB/TrEMBL:Q9L190" FT /protein_id="CAB76286.1" FT /translation="MIEWVPLGSGARPVPRPVADPLVWAGAFGGALLLVGLLNGIVGAG FT RPGLALVALSLLAALLGLCARFTAAPGTAVLCWLSLNGFAIPPAGTLTWTGRRDAFWLA FT CLLGAALVGTALARLVHARAAYRRLTTATGLDVPEPGTGPGDV" FT CDS complement(136068..137240) FT /transl_table=11 FT /gene="SCO7386" FT /gene_synonym="SC10G8.13c" FT /product="putative secreted serine protease." FT /note="SC10G8.13c, possible secreted serine protease, len: FT 390 aa. Similar to many serine proteases e.g. Streptomyces FT griseus SW:PRTC_STRGR(EMBL:L29018) serine protease C FT precursor (EC 3.4.21.-) (457 aa), fasta scores opt: 983 FT z-score: 1020.1 E(): 0 44.4% identity in 403 aa overlap FT and Streptomyces sp. TR:Q55353(EMBL:X74102) alkaline serine FT protease II (382 aa), fasta scores opt: 959 z-score: 996.4 FT E():0 44.7% identity in 403 aa overlap. Contains a Prosite FT hits to PS00134 Serine proteases, trypsin family, histidine FT active site PS00135 Serine proteases, trypsin family, FT serine active site and a Pfam match to entry PF00089 FT trypsin, Trypsin. Also contains a possible N-terminal FT signal sequence." FT /db_xref="GOA:Q9L189" FT /db_xref="HSSP:1GBJ" FT /db_xref="InterPro:IPR018114" FT /db_xref="UniProtKB/TrEMBL:Q9L189" FT /protein_id="CAB76287.1" FT /translation="MRRSRLRHLGLAGLLVLGSLTAVGTLPASAADAPAHSPSSSEQPA FT SAGLLDAMQRDFGLTRAEAEDRLAAEREATGIEPAARRAAGKAFGGSWFDAEAGRLTVA FT VTSDATPSALRAVRATGAQVRTVEHSAQQLDAAKARVDRLDAPAGVSSWRADRATNKVV FT VDVVAGERADNDVQSFLKQARATAPVTVRTVPSAPQTFAAGTVGGDPYYTGNVRCSIGF FT SVHGGFVTAGHCGRAGAGVSGWDRSYIGTFQGSSFPDNDYAWVSVGSGWWTVPVVLGWG FT TVSDQLVRGSNVAPVGASICRSGSTTHWHCGTVLAHNETVNYSDGSVVHQLTKTSVCAE FT GGDSGGSFISGDQAQGVTSGGWGNCSSGGETWFQPVNEILNRYGLTLHTA" FT misc_feature complement(136092..136628) FT /note="Pfam match to entry PF00089 trypsin, Trypsin, score FT 46.80, E-value 5.5e-14" FT misc_feature complement(136194..136229) FT /note="PS00135 Serine proteases, trypsin family, serine FT active site" FT misc_feature complement(136539..136556) FT /note="PS00134 Serine proteases, trypsin family, histidine FT active site" FT CDS 137503..138009 FT /transl_table=11 FT /gene="SCO7387" FT /gene_synonym="SC10G8.14" FT /product="hypothetical protein SC10G8.14." FT /note="SC10G8.14, unknown, len: 168 aa; similar to another FT from Streptomyces coelicolor SC8D11.07 TR:Q9AK12 FT (EMBL:AL512944) hypothetical protein fasta scores; opt: FT 426, Z-score: 537.3, E(): 2.7e-22, 46.763% identity FT (46.763% ungapped) in 139 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9L188" FT /protein_id="CAB76288.1" FT /translation="MAIRHRLIQATPDAVWDVLADGDLYVEWVVGPSEVTPRAGQWPQV FT GATIAYEVRLGPLRLNNESVVRRCVPGSELELEAKAGRLGTARIAVELRPWGEQCLVIV FT DEHPLRGPGGLLHNVGVEALIQVRHRAMLARLAKLCESTAGERCRPDPSDTTGSVEYRP FT GTGRA" FT CDS 138002..139621 FT /transl_table=11 FT /gene="SCO7388" FT /gene_synonym="SC10G8.15" FT /product="putative dehydrogenase." FT /note="SC10G8.15, possible dehydrogenase, len: 539 aa. FT Similar to many including: Synechocystis sp. FT TR:Q55808(EMBL:D64004) phytoene dehydrogenase (542 aa), FT fasta scores opt: 605 z-score: 655.2 E(): 4.5e-29 31.7% FT identity in 543 aa overlap and Rhodobacter sphaeroides FT SW:CRTD_RHOSH(EMBL:X63204) methoxyneurosporene FT dehydrogenase, CrtD (495 aa), fasta scores opt: 268 FT z-score: 292.4 E(): 7.2e-09 28.2% identity in 528 aa FT overlap." FT /db_xref="GOA:Q9L187" FT /db_xref="InterPro:IPR000759" FT /db_xref="UniProtKB/TrEMBL:Q9L187" FT /protein_id="CAB76289.1" FT /translation="MPDAVVVGAGPNGLVAANLLADAGWSVTVLEEQPEPGGAVRHDGE FT VAPGFVNDLFSSFYPLAAASPVLGGLRLEEHGLRWAHAPHVLAHPLTDGTCAVLDRDVA FT TTAASLDAFALGDGAAWERLHAVWDRYRADILDALFTPFPPVRATARLALRLRGAGGLR FT LARTLVLPVRRMGEEEFRGEGGRLLLAGNALHADLAPEAAGSGGFGWLMSMLGQTYGFP FT VPVGGSGALTEALVHRLRARGGTLHCGRRVERVLVRDRRAVGVRTADGETVTARRAVLA FT NVSVPALYGRLVAPADLPDQVLTDLRRFQWDFATFKVDWALDGPVPWQCEAAARAGTVH FT LSDGLDELTRFAAQIAMRQVPDRPFSLFGQMTTTDPTRSPRGTESAWAYTHVPHDIRAD FT AGEEGITGTWDTGERELMADRVERQVERFAPGFRALIRARRVLAPPTLQALDANLEGGA FT INGGTTAMHQQLVFRPVPGTGRPETPVAGLFLASAGAHPGGGVHGAPGANAARAALRQH FT RFAGLARIQRALTRRDRAGDRH" FT CDS 139665..140543 FT /transl_table=11 FT /gene="SCO7389" FT /gene_synonym="SC10G8.16" FT /product="putative oxidoreductase." FT /note="SC10G8.16, possible oxidoreductase, len: 292 aa. FT Similar to many including: Streptomyces clavuligerus FT TR:O54197(EMBL:AJ000671) clavulanate-9-aldehyde reductase FT (247 aa), fasta scores opt: 352 z-score: 389.3 E(): FT 2.9e-14 33.0% identity in 221 aa overlap and Streptomyces FT coelicolor TR:CAB59666(EMBL:AL132674) probable FT oxidoreductase, SCE87.21c (297 aa), fasta scores opt: 931 FT z-score: 1011.4 E():0 52.8% identity in 286 aa overlap. FT Contains a Prosite hit PS00061 Short-chain FT dehydrogenases/reductases family signature and a Pfam match FT to entry PF00106 adh_short, short chain dehydrogenase." FT /db_xref="GOA:Q9L186" FT /db_xref="HSSP:1FDU" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9L186" FT /protein_id="CAB76290.1" FT /translation="MTDSPLQNRTVVVTGAARGLGAALARACALRGARIALLGLEKPRL FT DALAADLPTPALAVEADVTDPAALADAAGETRRRLGRPSVVVANAGVAHGGPFATSDPA FT EWGRVVDVNLTGSAHTARAFLPDLLDTAGYHLQIASLASLGAAPMMSAYCASKAGVEAF FT AHSLRAEVAHRGVAVGIAYLNWIDTDMIRDADRHPVLRELRAHMPPPARRTFSADDVAA FT RLVRALERRRTAVYVPGWLRLVQLGRASLPPVVARLSRRELPRLEAEEELGPTGPLGAG FT GRAGHAAGTRT" FT misc_feature 139689..140231 FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 154.50, E-value 1.8e-42" FT misc_feature 140082..140168 FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT CDS complement(140594..141097) FT /pseudo FT /transl_table=11 FT /gene="SCO7390" FT /gene_synonym="SC10G8.17c" FT /product="putative dehydrogenase (pseudogene)." FT /note="SC10G8.17c, possible dehydrogenase, pseudogene, len: FT 168 aa. Highly similar to the C-terminus of Streptomyces FT griseus TR:P72449(EMBL:X95596) dehydrogenase found within FT the crt genes for carotenoid biosynthesis (517 aa). Also FT highly similar to Streptomyces coelicolor FT TR:CAB53156(EMBL:AL109962) putative dehydrogenase FT (fragment), CrtU or SCJ1.38c (>336 aa)." FT repeat_region 141387..141479 FT /note="degenerate repeat region containing FT 6xCGGA(C/G)GG(G/C), 2xCCGC and 2xACTGC repeats." FT CDS 141616..141951 FT /pseudo FT /transl_table=11 FT /gene="SCO7391" FT /gene_synonym="SC10G8.18" FT /gene_synonym="SC10G8.19" FT /product="putative phytoene dehydrogenase" FT /note="SC10G8.18, possible phytoene dehydrogenase, FT pseudogene, len: 108 aa. This CDS appears to be a gene FT fragment which is highly similar to the N-terminus of many FT phytoene dehydrogenases e.g. Streptomyces griseus FT SW:CRTI_STRGR(EMBL:L37405) phytoene dehydrogenase, CrtE FT (507 aa). Also highly similar to Streptomyces coelicolor FT TR:CAB53153(EMBL:AL109962) putative phytoene dehydrogenase, FT CrtE or SCJ1.35 (523 aa)." FT /note="SC10G8.19, possible methylesterase, pseudogene, len: FT 37 aa. Possible gene fragment which is highly similar to FT the C-terminus of Streptomyces coelicolor FT TR:CAB53155(EMBL:AL109962) putative methylesterase, CrtV or FT SCJ1.37 (336 aa)." FT /db_xref="PSEUDO:CAD55400.1" FT RBS 142046..142049 FT CDS 142060..142551 FT /transl_table=11 FT /gene="SCO7392" FT /gene_synonym="SC10G8.20" FT /product="hypothetical protein SC10G8.20." FT /note="SC10G8.20, unknown, len: 163 aa." FT /db_xref="UniProtKB/TrEMBL:Q9L185" FT /protein_id="CAB76293.1" FT /translation="MQTFLPHPGFRDSALALDRRRLGKQRVEALQVLRGLTVPGYGWRR FT HPAVRMWTGYEEALVRYGLDVCRVWREHGHQDSCAASLVAGLAEVRPGEPVRDQEELSA FT AGELPPWLGDEAFHRSHRSALVRKEPEVYAELFPGVPDDLPYVWPSSDRERGEADGGRS FT " FT CDS complement(142557..143306) FT /transl_table=11 FT /gene="SCO7393" FT /gene_synonym="SC10G8.21c" FT /product="putative lipoprotein." FT /note="SC10G8.21c, possible lipoprotein, len: 249 aa. FT Weakly similar to Streptomyces coelicolor FT SW:YRJ1_STRCO(EMBL:L24552) hypothetical protein in RplJ FT 5'region (Orf 1) (fragment) (>256 aa), fasta scores opt: FT 120 z-score: 142.7 E(): 1.6 20.3% identity in 261 aa FT overlap. Contains a possible N-terminal signal sequence and FT an appropriately positioned Prosite hit to PS00013 FT Prokaryotic membrane lipoprotein lipid attachment site." FT /db_xref="UniProtKB/TrEMBL:Q9L184" FT /protein_id="CAB76294.1" FT /translation="MRTGKVATAVATASVSVALLAGCGGDSGDEGKPFEGQSADDIAAK FT AVEATRQAKSVHVKGDTRLEDGSTVTIDVSVDQEKNCQGTIGAGETRADVRHTDATLYL FT RGDEQYWRTALEQQPDAARKMAPKLQDKWVRMPANDASTAGVCDKQGFIAAMDEDESER FT RGMKRGSTTEVNGEEALKLTKDASGGEKLTLYVATEGEPYILKTTTEGGENPGGVTFSE FT YGKTVDPQQPPADETVDMKELAGEQQT" FT misc_feature complement(143238..143270) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site." FT CDS 143523..144461 FT /transl_table=11 FT /gene="SCO7394" FT /gene_synonym="SC10G8.22" FT /product="putative integral membrane protein." FT /note="SC10G8.22, possible integral membrane protein, len: FT 312 aa. Similar to several proteins of undefined function FT e.g. Deinococcus radiodurans TR:AAF11939(EMBL:AE002070) FT Conserved hypothetical protein (304 aa), fasta scores opt: FT 227 z-score: 259.6 E(): 4.8e-07 29.4% identity in 310 aa FT overlap. Contains multiple possible membrane spanning FT hydrophobic domains and a possible N-terminal signal FT sequence." FT /db_xref="GOA:Q9L183" FT /db_xref="InterPro:IPR000620" FT /db_xref="UniProtKB/TrEMBL:Q9L183" FT /protein_id="CAB76295.1" FT /translation="MNATTTRGSLLAALACVLVGGSFTANSLLGDYPYAGGQFLRYGLA FT FLLLVPLAGPGAAARLRALGAARWLRLALLAAVGMVGFNLAVLAAERTAEPAVPGVFVG FT CAPVVVAVLVPLLEGRRPQRIVLYGALFVAVGAFTVQGWGRTDGAGIAFSVCALVGEVG FT FAVLAVPVLRPLGPRLLSTVVCGVAAAESALAGVLADGTGWLRRPDAVEAGALLWQAVV FT VTVVGFVCWYMGMQRIGAERATLFSGLIPVAAACTAPLVGTGSYGAAQAVGSALVFAGV FT AVGSGAALPSARARRSAAERQTAPERSLEKL" FT CDS complement(144425..145990) FT /transl_table=11 FT /gene="SCO7395" FT /gene_synonym="SC10G8.23c" FT /product="putative membrane transport protein." FT /note="SC10G8.23c, possible membrane transport protein, FT len: 521 aa. Highly similar in several transport proteins FT involved in osmoregulation e.g. Escherichia coli FT SW:PROP_ECOLI(EMBL:M83089) proline/betaine transporter FT (proline porter II), ProP (500 aa), fasta scores opt: 1557 FT z-score: 1688.1 E():0 47.9% identity in 466 aa overlap. FT Contains Prosite hits to PS00217 Sugar transport proteins FT signature 2 and PS00216 Sugar transport proteins signature FT 1, as well as a Pfam match to entry PF00083 sugar_tr, Sugar FT (and other) transporter. Also contains multiple possible FT membrane spanning hydrophobic domains." FT /db_xref="GOA:Q9L182" FT /db_xref="InterPro:IPR005829" FT /db_xref="UniProtKB/TrEMBL:Q9L182" FT /protein_id="CAB76296.1" FT /translation="MAERRRGDGVVEAKPDGGSGPPDGAKMPSTIAHLPQQVREELTRR FT LRRTRRAFGEDDVQVVEAPLLKRAVGASALGNCMEWFDFGVYSYLAATIGKVFFPGASP FT AAQVISSFATFAAAFVVRPLGGLVFGPLGDRVGRQKVLATTMIMMALGTFSIGLIPSYA FT TIGIAAPILLLLARMVQGFSTGGEYGGATTFVAEYSPDRRRGFLSSWLDFGTFVGYALG FT SALVTVLNLALTDAQMLHWGWRLPFLIAGPLGVIGLYMRLKLEESPAFQQQLDEHEKGL FT AQESAGSEFKTIVREHWRPLLVCMGLVLLYNVTNYMVTGYLPTYQTETLDRSSGFADVL FT VLIGMVWIVLLITFLGRLSDHVGRRPLYATGAAAMIVLAVPAFLLLKADGVWAPVAGVL FT LLSTLLACFAAPSAATLPALFPTAVRYAAMAIGFNFAVAAFGGTTPLVAEALVSITGDE FT LMPAYYLMVAGAVGLVTVKFLPESAQVPLHGSQPMVGSRQEQRELITTSKDLYSFSKDR FT SGAV" FT misc_feature complement(144509..145789) FT /note="Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter, score 204.30, E-value 1.9e-57" FT misc_feature complement(144875..144928) FT /note="PS00216 Sugar transport proteins signature 1" FT misc_feature complement(145379..145456) FT /note="PS00217 Sugar transport proteins signature 2" FT CDS complement(146050..147387) FT /transl_table=11 FT /gene="SCO7396" FT /gene_synonym="SC10G8.24c" FT /product="putative secreted protein." FT /note="SC10G8.24c. possible secreted protein, len: 445 aa. FT Weakly similar to Mycobacterium tuberculosis FT TR:O06598(EMBL:Z95586) hypothetical 48.0 KD protein (446 FT aa), fasta scores opt: 399 z-score: 416.0 E(): 9.3e-16 FT 28.2% identity in 387 aa overlap. Contains a possible FT N-terminal signal sequence." FT /db_xref="GOA:Q9L181" FT /db_xref="InterPro:IPR005152" FT /db_xref="UniProtKB/TrEMBL:Q9L181" FT /protein_id="CAB76297.1" FT /translation="MPPRPRMLAAAITAALALGAQAVPAAAADGPAGDSTATTSRGVEI FT PAFYTPPSELPAADGTLIRHEPLPLALSLPGIDGPLPGRATRLMYKSTDANGEAVAVTG FT AYVEPAAKWRGDGPRPLVAVAPGTMGQGDQCAASMALEHPLQLNGQTVSVGYEDLSVYR FT LLLRGVAVVVTDYVGLGTTDRLHTYVNRVDGAHAVLDAVRAARSLDSASVTSDSRVGLF FT GYSQGGGATAAAAELQPSYAPDVQLAGTYAGAPPADLTEVTKAIDGSDLAGALGWSLNG FT FLQTEPALRPIADRYINEAGQEALKDLSTMCVGDALFGYGGDSSTDWTRTGQSISDVIR FT AEPALQSFLAEQRIGSTAPGSPVRVATGVSDDLVPHGQARRLAVDWCGKGGKVTYVPVL FT IPGVGSGLLNHFAPLLADQGNAIAWLTDRLSGEPAGSNCWSMPVQP" FT RBS complement(147393..147399) FT CDS complement(147545..148141) FT /transl_table=11 FT /gene="SCO7397" FT /gene_synonym="SC10G8.25c" FT /product="conserved hypothetical protein SC10G8.25c." FT /note="SC10G8.25c, unknown, len: 198 aa. Weakly similar to FT several e.g. Bacillus subtilis TR: O05231(EMBL:Z93933) FT hypothetical 23.8 KD protein (205 aa), fasta scores opt: FT 213 z-score: 271.6 E(): 1e-07 28.2% identity in 181 aa FT overlap." FT /db_xref="GOA:Q9L180" FT /db_xref="InterPro:IPR013520" FT /db_xref="UniProtKB/TrEMBL:Q9L180" FT /protein_id="CAB76298.1" FT /translation="MDRRATVGGHAGLLNVIDLEATCWDGQPPPGEVSEIVEIGLAVVD FT LDARERVGRHRILVRPTRSRVSAFCTELTGITQAEADRGVSLARACDTLVREHGAGARP FT WASWGDYDRKQFVRQCAADGVPYPFGHPAERAHTNAKAVFTEAHGLRRRPGMAQALEIA FT GLPLAGRHHRGVDDAWNIAALVLRLADRDAWPGSC" FT CDS complement(148201..150285) FT /transl_table=11 FT /gene="SCO7398" FT /gene_synonym="SC10G8.26c" FT /product="putative membrane transport protein." FT /note="SC10G8.26c, possible membrane transport protein, FT len: 694 aa. Highly similar to many members of the FecCD FT family of binding protein-dependent transport proteins e.g. FT Escherichia coli SW:FHUB_ECOLI(EMBL:X04319) ferrichrome FT transport protein FhuB precursor (660 aa), fasta scores FT opt: 510 z-score:0.0 E(): 0.0 33.93% identity in 672 aa FT overlap. Contains 2xPfam match to entry PF01032 FT FecCD_family, FecCD transport family and multiple possible FT membrane spanning hydrophobic domains." FT /db_xref="GOA:Q9L179" FT /db_xref="InterPro:IPR000522" FT /db_xref="UniProtKB/TrEMBL:Q9L179" FT /protein_id="CAB76299.1" FT /translation="MAVTTTESATEPTAARPSTVPSSRSGAAAVTAGIVLLVAVLAVVD FT ITQGTAAVGPSEVFKALTGRADPDDASVVVASRLPRMTAGLLVGAVLGMAGAVLQAVSR FT NVLASPDTLAVNAGSYLALGLAGATGVSLPMLASSGIAFVGGLAAAAVVLGLSGLGTGT FT VRLVLAGTALMLGLHSMTQALLLLFPEQTKGLYEWNQGSIAQNGFDGVLQMLPIALAGV FT AGLLLTARRVDALALGDDAARGLGVPVRATRLTVVVLAALLSAAAVTLAGPIGFVGLCA FT PALVRPLARRFRGFSRSRTAMPAAALTGAALVLGSDVLLRALIADDRSVAVPTGVVTSL FT VGAVFLVTMALRVRDTAGAGAPDRLRIPGRAVFLATVAVLVVVLVGLVIAAVLVGDTKL FT LLGDVANWAQGRAGRTVSFVLDTRVPRVLAALGAGAALALAGTLVQAVTRNPLAEPNVL FT GVTGGGALGAVILVTTVPAAGTWGVAGAAFAGSAVSAVLVFGLAARGGFRQNRLVLVGI FT GVASGTAALISLLIVLTDPFNANKALTWLSGSTYGRTMPDVVPVALALLVGIGVAVARR FT TELDLISLDEDTPRLLGLRLAPGRLGFLVLSVVLSATAVACAGTIGFVGLVAPHAARAL FT VGRRHVRVVPVAILLGATLVCAADLLGRTVIAPAQLGAGLMTAVIGTPYFLYLLVRSRR FT " FT misc_feature complement(148213..149103) FT /note="Pfam match to entry PF01032 FecCD_family, FecCD FT transport family, score 279.50, E-value 4.3e-80" FT misc_feature complement(149230..150141) FT /note="Pfam match to entry PF01032 FecCD_family, FecCD FT transport family, score 228.80, E-value 8.1e-65" FT CDS complement(150293..151276) FT /transl_table=11 FT /gene="SCO7399" FT /gene_synonym="SC10G8.27c" FT /product="possible binding-protein-dependent transport FT lipoprotein." FT /note="SC10G8.27c, possible binding-protein-dependent FT transport lipoprotein, len: 327 aa. Similar to many FT including: Escherichia coli SW:FHUD_ECOLI(EMBL:X05810) FT ferrichrome-binding periplasmic protein precursor FhuD (296 FT aa), fasta scores opt: 231 z-score: 249.9 E(): 1.7e-06 FT 24.8% identity in 270 aa overlap. Contains a possible FT N-terminal signal sequence and an appropriately positioned FT Prosite hit to PS00013 Prokaryotic membrane lipoprotein FT lipid attachment site. Also contains a Pfam match to entry FT PF01497 Peripla_BP_2, Periplasmic binding protein." FT /db_xref="GOA:Q9L178" FT /db_xref="InterPro:IPR002491" FT /db_xref="UniProtKB/TrEMBL:Q9L178" FT /protein_id="CAB76300.1" FT /translation="MRRLLLTAAATTAAALTLAACGTTEPAADKAEKKASEAITLKDGK FT GTEVKLDGPATKVVATEWNVVESLVSLGVDPVGVADVKGYKTWDSAVPLKNEPKDIGTR FT GEPSMDTVASLAPDLIVATTDLAPAAVKQLREVAPVIEVKSADGTGQIDRMLENVDLIA FT EATGTTDRAKSLREGFETKVAEGKKALADAGMAGKDIAFADGYVASNQVSIRPYTATSL FT IGEVNEAVGLKNAWTVKGDEAYGLGATDVEGLTKLPEDTQFAYIGNDDDPSATPFTGEL FT AKNPVWKSLPFVKAGDVHRLDDGIWMFGGPGSMEAYIDAVVGALTK" FT misc_feature complement(150362..151117) FT /note="Pfam match to entry PF01497 Peripla_BP_2, FT Periplasmic binding protein, score 55.60, E-value 1.1e-12" FT misc_feature complement(151214..151246) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site." FT CDS complement(151273..152151) FT /transl_table=11 FT /gene="SCO7400" FT /gene_synonym="SC10G8.28c" FT /product="putative ABC-transport protein, ATP-binding FT component." FT /note="SC10G8.28c, possible ABC-transport protein, FT ATP-binding component, len: 292 aa. Highly similar to many FT e.g. Escherichia coli SW:FEPC_ECOLI(EMBL:X57471) ferric FT enterobactin transport ATP-binding protein, FepC (271 aa), FT fasta scores opt: 670 z-score: 720.4 E(): 1e-32 41.7% FT identity in 266 aa overlap and Escherichia coli FT SW:FHUC_ECOLI(EMBL:X05810) ferrichrome transport FT ATP-binding protein, FhuC (265 aa), fasta scores opt: 569 FT z-score: 613.5 E(): 9.2e-27 39.2% identity in 240 aa FT overlap. Also similar to Streptomyces coelicolor FT TR:CAB53325(EMBL:AL109974) putative iron-siderophore FT ABC-transporter, ATP-binding protein, SCF34.14c (287 aa), FT fasta scores opt: 728 z-score: 571.3 E(): 2.3e-26 46.7% FT identity in 274 aa overlap. Contains Prosite hits to FT PS00211 ABC transporters family signature and PS00017 FT ATP/GTP-binding site motif A (P-loop). Also contains a Pfam FT match to entry PF00005 ABC_tran, ABC transporter." FT /db_xref="GOA:Q9L177" FT /db_xref="HSSP:1L7V" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9L177" FT /protein_id="CAB76301.1" FT /translation="MRSGEDAAGTPRLRGHELSATGVTVAYDGVDVVHDAGVRLRPGEV FT TVLVGPNGSGKSTLLRTVARLQRARSATLSLDGATDGLALTSREFSRYVALLTQGRPTP FT GGLTVRDVVEFGRYPYRGRWGRPDPDGPAAVERALALTGVDGLADRGADHLSGGQLQRV FT WLASCLAQETGVLLLDEPTTYLDLRYQVELLDLIRDLADDHGIAVGVVLHDLDQAAAVA FT DRITLLEAGRIVADGPPEDVLTPERLTAVYGIRIDVDTDPLTGRLRTRPIGRHHIRTPR FT TRTPERLGTTS" FT misc_feature complement(151459..152025) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 158.50, E-value 1.1e-43" FT misc_feature complement(151645..151689) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(151981..152004) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(152255..152824) FT /transl_table=11 FT /gene="SCO7401" FT /gene_synonym="SC10G8.29c" FT /product="conserved hypothetical protein" FT /note="SC10G8.29c, unknown, len: 189 aa. Similar to FT Deinococcus radiodurans TR:AAF11944 (EMBL:AE002070) FT Conserved hypothetical protein (200 aa), fasta scores opt: FT 394 z-score: 504.8 E(): 1.1e-20 42.9% identity in 156 aa FT overlap" FT /db_xref="GOA:Q9L176" FT /db_xref="InterPro:IPR011576" FT /db_xref="UniProtKB/TrEMBL:Q9L176" FT /protein_id="CAB76302.1" FT /translation="MPHTTVTTGDRPDAATATEEGWVELDSRAHLRELLGEPWPLVIDK FT VHDRLTDDDRDILARSPFCLLATSDAGGNCDVSPRGDVPGFTHVLDSRTLALPDRAGNR FT RGDSFHNVLDNPHAGLLYLIPGGKEVLRVNGRARILTDAPFFDAMARGGRRPDLALLLE FT IDEIYLHCPMSLNRAGLWNSGSAQAS" FT CDS complement(152910..154082) FT /transl_table=11 FT /gene="SCO7402" FT /gene_synonym="SC10G8.30c" FT /product="putative lyase." FT /note="SC10G8.30c, possible lyase, len: 390 aa. Weakly FT similar to Bacillus subtilis SW:SPL_BACSU(EMBL:L08809) FT spore photoproduct lyase (EC 4.1.99.-), SplB (342 aa), FT fasta scores opt: 285 z-score: 328.4 E(): 7.1e-11 26.8% FT identity in 347 aa overlap." FT /db_xref="GOA:Q9L175" FT /db_xref="UniProtKB/TrEMBL:Q9L175" FT /protein_id="CAB76303.1" FT /translation="MHDPSTAPDDGFGTLFGLDALTPGPPPVAGPRFRDSAAARRLLPV FT REIHAEPAAAASPRGRQILARFPDARVVEVDSHWGIPGLHGNEGNVERWVRVKGETLVL FT GERKTLATRPNGRSADWIAPGASNGCAMACAYCYVPRRKGYANPVTVFTNIERIVAHLG FT RHIARQGPKREPNQCDTEAWVYDIGENGDCSVDALICDNTADLVHAFRQWPTAKASFAT FT KFVNPDLLALDPRGRTRVRFSLMPPDDSRLLDVRTSPVAERIAAAGDFLEAGYEVHFNL FT SPVVLRPGWEEAWAQLLRQLDDVLPDRVKRQAAAEVIMLTHNLGLHEVNLGWHPRAEEV FT LWRPEVQQAKRSENGALNVRYRADVKAGAVARLRALVAAHAPWLRIRYAF" FT CDS 154238..154423 FT /transl_table=11 FT /gene="SCO7403" FT /gene_synonym="SC10G8.31" FT /product="putative membrane protein" FT /note="SC10G8.31, putative membrane protein, len: 61 aa. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9L174" FT /protein_id="CAB76304.1" FT /translation="MYTVLAIIAAVLFLIAWLINAAEVSTNDVFTATNVMLIGLALLAL FT HVAGVGSGWAPRGRRR" FT CDS complement(154457..155248) FT /transl_table=11 FT /gene="SCO7404" FT /gene_synonym="SC10G8.32c" FT /product="conserved hypothetical protein SC10G8.32c." FT /note="SC10G8.32c, unknown, len: 263 aa. Highly similar to FT a number of proteins of undefined function from FT Streptomyces coelicolor including: TR:O86541 FT (EMBL:AL031350) SC1F3.04 (261 aa), fasta scores opt: 1155 FT z-score: 1354.8 E():0 67.9% identity in 262 aa overlap and FT TR:O86718 (EMBL:AL031515) SC5C7.21C (271 aa), fasta scores FT opt: 894 z-score: 1050.3 E(): 0 54.0% identity in 272 aa FT overlap." FT /db_xref="InterPro:IPR006764" FT /db_xref="UniProtKB/TrEMBL:Q9L173" FT /protein_id="CAB76305.1" FT /translation="MTTDHTQPPQIDTGRAHPARVYDWLLGGKDNYPVDEAVGETLPPE FT ARDAARQNRAFMNRAVAHLAARGIDQFLDIGTGIPTEPNLHQIVQRTVPAARVVYADND FT PIVLRHAEALLVSSPEGATDYIQADVREPGEIVRHARGILDFDRPIALSLIALMHFVPD FT DQDAHGIVRGLVETLPAGSHLVLSHAALDLFPELAEQVIAQYAKGGIRLGFRTRAEVAR FT FFDGLELVPPGLVTATEWYGEGLEPPAPEASGIYAGVARIP" FT CDS complement(155360..156007) FT /transl_table=11 FT /gene="SCO7405" FT /gene_synonym="SC6D11.01c" FT /gene_synonym="SC10G8.33c" FT /product="putative acetyltransferase (fragment)." FT /note="SC6D11.01c, possible acetyltransferase, partial CDS, FT len: > 72 aa. Similar to the N-terminus of Escherichia coli FT SW:THGA_ECOLI(EMBL:J01636) galactoside O-acetyltransferase FT (EC 2.3.1.18) (203 aa), fasta scores opt: 138 z-score: FT 187.9 E(): 0.0048 38.3% identity in 60 aa overlap. Overlaps FT and extends into CDS SC10G8.33c on the adjoining cosmid." FT /note="SC10G8.33c, possible acetyltransferase, partial CDS, FT len: > 175 aa. Highly similar to a number of FT acetyltransferases e.g. Escherichia coli FT SW:THGA_ECOLI(EMBL:J01636) galactoside o-acetyltransferase FT (EC 2.3.1.18) LacA (203 aa), fasta scores opt: 592 z-score: FT 679.4 E(): 2e-30 48.8% identity in 160 aa overlap. FT Contains a Prosite hit to PS00101 Hexapeptide-repeat FT containing-transferases signature and a Pfam match to entry FT PF00132 hexapep, Bacterial transferase hexapeptide (four FT repeats)." FT /db_xref="GOA:Q8CJK1" FT /db_xref="HSSP:1KRR" FT /db_xref="InterPro:IPR018357" FT /db_xref="UniProtKB/TrEMBL:Q8CJK1" FT /protein_id="CAD55401.1" FT /translation="MTTDPREREVRRRMAARELYSDGAPGLAALAEERLRGKELADAYN FT RTGARDEEGRRALLKEMLAALGTGVWIEPPLHVAYGNRVHLGDDVYANFGLTLVDDVEV FT FVGDRVMFAPHVTVSTTGHPVHPDLRRDGTQFSAPVRIEDDVWIGAGAQIMPGVTVGRG FT SVVGAGSVVTAHVPPMTVVAGTPARVLREITDADREWSYRPPRTLGPGPGPG" FT misc_feature complement(155480..155566) FT /note="PS00101 Hexapeptide-repeat containing-transferases FT signature" FT misc_feature complement(155480..155584) FT /note="Pfam match to entry PF00132 hexapep, Bacterial FT transferase hexapeptide (four repeats), score 62.90, FT E-value 5e-16" FT RBS complement(156013..156017) FT stem_loop complement(156036..156086) FT /note="stem loop with 100% matches over 19 bases and a loop FT region of 13 bases." FT CDS complement(156101..158176) FT /transl_table=11 FT /gene="SCO7406" FT /gene_synonym="SC6D11.02c" FT /product="putative secreted protein." FT /note="SC6D11.02C, possible secreted protein, len: 691 aa. FT Contains a 8xGT repeat region within the C-terminus and a FT possible N-terminal signal sequence." FT /db_xref="GOA:Q9L153" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:Q9L153" FT /protein_id="CAB76325.1" FT /translation="MARRTRSRRLLGAAVLTALTTGAALLGVPAQAEPAAAPASVTVRP FT DPSYQQEEFEGWGTSLVWFANATGDYPPEIREKLARLLFGDDGLGLNIARYNIGGGNAP FT DVKDYLRAGGAVEGWWQAPEGTTREDTDWWSADDPADWNEDADATQRWWVERIKDDIDH FT WETFSNSPPWFMTVSGYVSGGFDSSADQLKPESVDDFAAYVAGATRRLEKAEGIEVDTV FT DPFNEPNTPYWGTQLGADGEPVGGRQEGAHMGPELQRKVLRALAPALRKAKVKADVSAM FT DETNPGTFAKNWSAYSAADRALVGQMNVHTYGTGQRTTVRDLAKAADKPLWMSEVGGDW FT GDGQDFADMRPGLGLAQQIVDDLRELEPRAWVFWQPVEDYDNMKPGGESAKGGNWGSIQ FT LPFDCTAQDTLETCPIRTNTKFDTARNFTHFIKPGDRLIQTDDTSSAAAVTRDGKGASV FT VHVNRGTEARTVTLDLSKFRDVSRRATVTPVVTSADGKLEKQSPIRVSDRTATFTVPAQ FT SVTSFAIKGVSGVAKDAAGLRKGHTYTLTGVQSGKAVTVAADGTNLVLGTGTGTGTGTG FT TGTGTDPSARQWRLSAVRHDGGVRDRYVFTRPEDGTRLAVRDDVPVAEPDTGRRDRAAE FT WLASSTGDGTWTLVNSGTGRLLEVGGQATHDGAAVTTWPPNSGANQRWTLTDVSAG" FT repeat_region complement(156434..156481) FT /note="repeat region containing 8xGGCACC repeats." FT CDS complement(158304..160349) FT /transl_table=11 FT /gene="SCO7407" FT /gene_synonym="SC6D11.03c" FT /product=" probable beta-galactosidase." FT /note="SC6D11.03c, probable beta-galactosidase, len: 681 FT aa. Similar to many beta-galactosidases e.g. Bacillus FT stearothermophilus SW:BGAL_BACST(EMBL:M13466) FT beta-galactosidase I (EC 3.2.1.23), BgaB, (672 aa), fasta FT scores opt: 1816 z-score: 2079.7 E(): 0 43.2% identity in FT 666 aa overlap." FT /db_xref="GOA:Q9L152" FT /db_xref="HSSP:1KWG" FT /db_xref="InterPro:IPR013529" FT /db_xref="UniProtKB/TrEMBL:Q9L152" FT /protein_id="CAB76326.1" FT /translation="MISTLHSRLHRGADGAPAPRLAYGADYNPEQWPREVWEEDVRLMR FT EAGVNIVSLGIFSWARIQPGPDTWDFAWLDEVMDLLHEHGVGVDLATATASPPPWLTTA FT HPEILPVTDRGETLWPGARQHWRPTSPVFREHALRLVRKLATRYADHPALVAWHVNNEL FT GCHNVYDYSDDAARAFRDWLRARYGTTDALNHAWGTAFWSQRYGDWAEVLPPRLAASHP FT NPTQQLDFKRFSSDALKDHLRAERDLLRELTPDVPVTTNFMVMPGTKGMNYADWAGEVD FT FVANDHYVVPHPQARDELSFSANLTSGIAGGRPWFLMEHSTSAVNWQPVNLAKRPGEMA FT RDSLTHVAHGADAVCFFQWRQSAAGAEKYHSAMVPHAGADSVLFRAVTSLGDTLKTLAP FT VAGSEREPAEVGILFDWESRWASEQDSHPTSLLDYHQEALDWYSALLSLGVRADVVTTG FT ADLSRHRVLIAPVLHLVPAELAKDLTRYAEQGGHLVTTYFSGIVDENDHVWLGGYPGAL FT RDLLGIRVEEFGPLPAGQSVELDGAGSGDLWTDRITVTAPETEVLARYRTGTHTGHPAV FT TRRPAGRGSAAYVSTRLGADGLAALLPRLLEPAGVTSELPASVRGRVEATVRRGAGGRF FT LFLVNRTDEAVTVPGLTGDVLVGDTGDEGAVVLAGRGVAVLRTPTP" FT RBS complement(160355..160359) FT CDS complement(160376..161731) FT /transl_table=11 FT /gene="SCO7408" FT /gene_synonym="SC6D11.04c" FT /product="probable solute-binding lipoprotein." FT /note="SC6D11.04c, probable solute-binding lipoprotein, FT len: 451 aa. Similar to several other transport proteins FT including: Agrobacterium radiobacter FT SW:LACE_AGRRD(EMBL:X66596) lactose-binding protein FT precursor, LacE (422 aa), fasta scores opt: 347 z-score: FT 393.9 E(): 1.6e-14 24.0% identity in 425 aa overlap and FT Streptomyces coelicolor TR:CAB61177(EMBL:AL132973) probable FT solute-binding lipoprotein, SCF91.20 (443 aa), fasta scores FT opt: 550 z-score: 621.9 E(): 3.2e-27 26.2% identity in 455 FT aa overlap. Contains a possible N-terminal signal sequence FT and an appropriately positioned Prosite hit to PS00013 FT Prokaryotic membrane lipoprotein lipid attachment site. FT Also contains a Prosite hit to PS01037 Bacterial FT extracellular solute-binding proteins, family 1 signature FT and a Pfam match to entry PF01547 SBP_bacterial_1, FT Bacterial extracellular solute-binding protein." FT /db_xref="GOA:Q9L151" FT /db_xref="InterPro:IPR006061" FT /db_xref="UniProtKB/TrEMBL:Q9L151" FT /protein_id="CAB76327.1" FT /translation="MPTHLTKHSRRLLRGTVLVCALALGATACGDSDDGGSGQKAVSEA FT DIQAALKEGGTITVWAWEPTLKQVATDFEKEHPGVKVDLVNAGTNKDQYTALQNAISAK FT KGVPDVAQIEYYAMGQYALTKQLTDLKSFGADKLSAQFSPGPWNGVKAGSDGVYALPMD FT SGPMALFYNKKVFDKYDIKVPTTWAEYLDAARDLHKADPKAYITADNGDAGFATSMLWQ FT AGSRPYTVDGTKVKIDFSDQGAKTFTETWQQLIDEKLLASVPAWTDEWYKGLGDGSIAT FT LATGAWMPANLESGAKSASGDWRVAPMPQWKAGDKVSAENGGSALALPELGKNEALAYA FT FVEYANAGDGVQTRLKNGAFPATTADLQSTRFQDTAFPYFGGQKANKIFAESAADVPDD FT WSYLPYQVYANSVFNDTVGKAYVSGTTLAEGLESWQEASVKYGEEQGFTVEK" FT misc_feature complement(160433..161269) FT /note="Pfam match to entry PF01547 SBP_bacterial_1, FT Bacterial extracellular solute-binding protein, score FT 56.40, E-value 6.1e-13" FT misc_feature complement(161198..161251) FT /note="PS01037 Bacterial extracellular solute-binding FT proteins, family 1 signature" FT misc_feature complement(161645..161677) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(161827..162777) FT /transl_table=11 FT /gene="SCO7409" FT /gene_synonym="SC6D11.05c" FT /product="putative binding-protein dependent transport FT protein." FT /note="SC6D11.05c, possible binding-protein dependent FT transport protein, len: 316 aa. Similar to many including: FT Streptomyces coelicolor TR:CAB61179(EMBL:AL132973) putative FT binding protein dependent transport protein, SCF91.22 (287 FT aa), fasta scores opt: 875 z-score: 1002.5 E(): 0 45.9% FT identity in 281 aa overlap. Contains possible membrane FT spanning hydrophobic domains and a Pfam match to entry FT PF00528 BPD_transp, Binding-protein-dependent transport FT systems inner membrane component." FT /db_xref="GOA:Q9L150" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9L150" FT /protein_id="CAB76328.1" FT /translation="MTSPVATASDRSAPPPSDTSRPAPRLRTPRRRHSADRPRRSVLLT FT VLTSLVLLYSLVPLVWLAVSATKTQEGLSRSAGLWFDGDFALWDNITETFTYDDGVFTR FT WLLNTLLYVGLGAGGATFLAVLGGYALAKFDFPGRRSVFAVVIGAVAVPGTALAVPTFL FT MFSKMGLTNTPWAVIIPSLISPFGLYLMWVFATEAIPTELMEAARIDGAGELRTFFRVA FT LPLLAPGIVTVLLFTMVATWNNYFLPLVMLKDPDWYPLTLGLNSWNQQAATAGGEAVFN FT LVVTGSLITILPLIAAFLLLQKYWQSGLAAGSVKE" FT misc_feature complement(161965..162195) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 71.40, E-value 1.9e-17" FT CDS complement(162785..163711) FT /transl_table=11 FT /gene="SCO7410" FT /gene_synonym="SC6D11.06c" FT /product="putative binding-protein dependent transport FT protein." FT /note="SC6D11.06c, possible binding-protein dependent FT transport protein, len: 308 aa. Similar to many other FT transport proteins e.g. Streptomyces coelicolor FT TR:CAB61178(EMBL:AL132973) putative binding protein FT dependent transport protein, SCF91.21 (328 aa), fasta FT scores opt: 622 z-score: 709.6 E(): 4.2e-32 35.9% identity FT in 315 aa overlap. Contains possible membrane spanning FT hydrophobic domains and a Prosite hit to PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign. Also contains a Pfam match to entry PF00528 FT BPD_transp, Binding-protein-dependent transport systems FT inner membrane component." FT /db_xref="GOA:Q9L149" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9L149" FT /protein_id="CAB76329.1" FT /translation="MTTLQPPAAAEPRPAPPPVRRDRRSWTGWGFLGPFVAVFALVFLA FT PIAYSVYLSLFRDQLIGGTTFVGLDNYAEALKDDRFWASLGRVSLFLAVQVPIMLGIAL FT LVALALDSGRLYGRDFFRISIFLPYAVPAVVATLMWGFMYGTRFGLVGDINGALGVSLP FT DPLSPDLVLASIGNIVTWEFVGYNMLIFYSALRVVPHSLYEAAQIDGAGQIRVITAIKL FT PAIRGALVIATIFSIIGSFQLFNEPSILQPLARNAITTDYTPNYYTYALSFNGQQHNYS FT ATVAIVMGLITMVVAYAVQLRGMRKGV" FT misc_feature complement(162908..163132) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 31.40, E-value 2e-05" FT misc_feature complement(163043..163129) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS 163904..164962 FT /transl_table=11 FT /gene="SCO7411" FT /gene_synonym="SC6D11.07" FT /product="putative LacI-family transcriptional regulator" FT /note="SC6D11.07, possible LacI-family transcriptional FT regulator, len: 352 aa. Similar to several including FT Escherichia coli SW:LACI_ECOLI (EMBL:V00294) lactose operon FT repressor LacI (360 aa), fasta scores opt: 595 z-score: FT 670.0 E(): 6.7e-30 34.8% identity in 333 aa overlap and FT Streptomyces coelicolor TR:O86618 (EMBL:AL031155) putative FT transcriptional regulator SC3A7.17 (361 aa), fasta scores FT opt: 887 z-score: 995.3 E(): 0 46.0% identity in 350 aa FT overlap. Contains Pfam matches to entries PF00356 lacI, FT Bacterial regulatory proteins, lacI family and PF00532 FT Peripla_BP_like, Periplasmic binding proteins and sugar FT binding domain of the LacI family. Possesses a putative FT helix-turn-helix motif situated between residues 23..44." FT /db_xref="GOA:Q9L148" FT /db_xref="HSSP:1PRU" FT /db_xref="InterPro:IPR001761" FT /db_xref="UniProtKB/TrEMBL:Q9L148" FT /protein_id="CAB76330.1" FT /translation="MSTAEEVPTSAPAPPRRGRDRTASMADVARLAGVSSQTVSRVSNG FT YAGVTEETRQQVLAAMKELGYRPNSAARALKRGEFRTIGVITFTLATTGNVRTLEAIAT FT SAASEGYAVTLLPVAVPTQDEVRGAFSRLEELAVDAVIVIMEVHLLDAASLKLPPHVQV FT VVVDSDAGDTYTVVDTDQAGGSRAAVRHLLDLGHDTVWHLGGPEGSFAAQRRTDAWRRT FT LTEAGRTPPPLVRGDWSAESGYRAGLELAAREDCTAVFAANDQMALGLLRALHERGRRV FT PEDISVIGFDDIAEAGSFLPPLTTVHQDFAEVGRLCVRAVLRKMRAAGPEQGTTLVPTR FT LVTRASTAPPPR" FT misc_feature 163964..164047 FT /note="Pfam match to entry PF00356 lacI, Bacterial FT regulatory proteins, lacI family, score 32.80, E-value FT 9.5e-08" FT misc_feature 164138..164854 FT /note="Pfam match to entry PF00532 Peripla_BP_like, FT Periplasmic binding proteins and sugar binding domain of FT the LacI family., score 70.10, E-value 4.5e-17" FT CDS 165072..166874 FT /transl_table=11 FT /gene="SCO7412" FT /gene_synonym="SC6D11.08" FT /product="putative pyruvate dehydrogenase (pyruvate FT oxidase)" FT /note="SC6D11.08, possible pyruvate dehydrogenase (pyruvate FT oxidase), len: 600 aa. Highly similar to many including: FT Escherichia coli SW:POXB_ECOLI(EMBL:X04105) pyruvate FT dehydrogenase (572 aa), fasta scores opt: 770 z-score: FT 855.7 E(): 0 34.6% identity in 566 aa overlap and FT Streptomyces coelicolor TR:Q9ZBT3(EMBL:AL034446) pyruvate FT dehydrogenase (pyruvate oxidase), SC1A9.19 (580 aa), fasta FT scores opt: 866 z-score: 962.2 E():0 33.1% identity in 556 FT aa overlap. Contains a Pfam match to entry PF00205 FT TPP_enzymes, Thiamine pyrophosphate enzymes. Also contains FT a Prosite hit to PS00187 Thiamine pyrophosphate enzymes FT signature." FT /db_xref="GOA:Q9L147" FT /db_xref="HSSP:1OZH" FT /db_xref="InterPro:IPR012000" FT /db_xref="UniProtKB/TrEMBL:Q9L147" FT /protein_id="CAB76331.1" FT /translation="MTQVADYVLQRLSEWGVQRVYGYPGDGINGLLGAFDRADGDPEFI FT QARHEEMAAFMACGHAKFTGEVGCCVATSGPGAVHLLNGLYDAKLDHQPVVAVVGQQKR FT LSLGTHYQQEIALDQLFADVSEYCQMVVHPGQARHVVDRAFKTALTTRGVATIIIPNDI FT QEEEAQPSPPREHGSVFSSVGWSRPRVLPDLDELRKAADVLNAGNKVAMLVGQGAANAE FT AEVKEVAELLGAGVAKALLGRQVLPDDLPYVTGPIGLLGSKASDNMIQGCDTLLMVGSS FT FPYSEWLPEEGQARGVEIDIDGRMIGIRYPMDAHLVGDSRETLRALIPMLQRKKDRGWR FT EKIEKDVREWHDLCDRWAGEHFGKTINPQAVAAELSARLPDDVILTADSGSGTNWWARH FT LLLRDGMQASLSGTLATMGPGTPYAIAARFAYPERPVIAFIGDGAFQMNGMNEMITVKR FT YLDRLSGSAPLIFCVFNNQDLNQVTWEQRAMAGDPKYPGSQDIPDVPYAAYAELLGLKG FT IVCDDPKKVGAAWDEALSAGRPVVLEFKVDAEIAPIPPHIMKEQGKKAIKAALHDPEAT FT GIATKGVRQKLTEYAEHLPGRGRK" FT misc_feature 165105..166703 FT /note="Pfam match to entry PF00205 TPP_enzymes, Thiamine FT pyrophosphate enzymes, score 340.80, E-value 2.4e-105" FT misc_feature 166344..166403 FT /note="PS00187 Thiamine pyrophosphate enzymes signature" FT CDS 166871..167902 FT /transl_table=11 FT /gene="SCO7413" FT /gene_synonym="SC6D11.09" FT /product="putative oxidoreductase." FT /note="SC6D11.09, possible oxidoreductase, len: 343 aa. FT Highly similar to many putative oxidoreductases including: FT Mycobacterium tuberculosis TR:O53398(EMBL:AL021897) FT oxidoreductase (301 aa), fasta scores opt: 405 z-score: FT 443.2 E(): 2.9e-17 36.2% identity in 257 aa overlap. FT Contains a Pfam match to entry PF00106 adh_short, short FT chain dehydrogenase and a Prosite hit to PS00061 FT Short-chain dehydrogenases/reductases family signature." FT /db_xref="GOA:Q9L146" FT /db_xref="HSSP:1FDU" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9L146" FT /protein_id="CAB76332.1" FT /translation="MSGARGHGQVVVVTGATGGVGRAAARAFGARGAAVALLARGEYAL FT ERAAEEIREAGGRALPLVVDVADAEAVDAAAGRVEEELGPIDVWVNAAFSTVFAPVPEI FT RPEELRRATEVTYFGFVHGTQAALRRMTPRDRGTIVQVGSALAERSVPLQAVYCGAKHA FT IQGFTESLRCELLHDRSGVRVTMVQMPGLNTPQFSWVLTRLPRHPRPVAPVYQPEVAAR FT AVLHAADHPERRMYWVGGSTVATLLGQKLAPGLLDRYLARTGYDGQQTDRPVDPSRPAN FT LWKPPDDTAPDDYGAHGIFDDEAHARSVQFWISRNRRRLALATAVTGAVAAALAGGLGR FT RAG" FT misc_feature 166895..167455 FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 164.00, E-value 2.5e-45" FT misc_feature 167300..167386 FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature." FT CDS complement(167906..168712) FT /transl_table=11 FT /gene="SCO7414" FT /gene_synonym="SC6D11.10" FT /product="putative integral membrane protein." FT /note="SC6D11.10, possible integral membrane protein, len: FT 268 aa. Contains possible membrane spanning hydrophobic FT domains." FT /db_xref="UniProtKB/TrEMBL:Q9L145" FT /protein_id="CAB76333.1" FT /translation="MNRLWRPFHRVWDWLAASALVRRGRDLELMHRAMGFATLALVTLA FT PLLIVVAAADPLGRGGFASWLADGMGLSGRSAKVLTDIISPPTKVVGTTSVWGGILLGV FT FGVSFAASVQNGYERIWELPSGPWHRIWRQMTWVALLTAYLYQEVQTRTALHGSARIAL FT STASGMLFFWWGQHFLLGGQVRWRDLLPGAVATMVGLIGLRGFSYLFFTPLILDNAFSY FT GAVGIVLVVESWLIGVGFVVFGGAMVGHWFCEHHWWARNIDRRPPD" FT RBS complement(168718..168722) FT RBS 168854..168858 FT CDS 168865..170022 FT /transl_table=11 FT /gene="SCO7415" FT /gene_synonym="SC6D11.11" FT /product="putative racemase." FT /note="SC6D11.11, possible racemase, len: 385 aa. Weakly FT similar to many racemases including: Pseudomonas putida FT SW:MANR_PSEPU(EMBL:M19043) mandelate racemase (EC 5.1.2.2) FT (359 aa), fasta scores opt: 315 z-score: 373.7 E(): 2.1e-13 FT 26.4% identity in 371 aa overlap and Streptomyces FT coelicolor TR:CAB55709(EMBL:AL117387) possible racemase, FT SCF41.06 (416 aa), fasta scores opt: 383 z-score: 452.6 FT E(): 8.7e-18 31.0% identity in 371 aa overlap. Contains a FT Pfam match to entry PF01188 MR_MLE, Mandelate racemase / FT muconate lactonizing enzyme family." FT /db_xref="GOA:Q9L144" FT /db_xref="InterPro:IPR001354" FT /db_xref="UniProtKB/TrEMBL:Q9L144" FT /protein_id="CAB76334.1" FT /translation="MTPLTGQDTPALDECVVDAVDVHAFEVPTDGPEGREQDGTLEWDA FT TTLVLVRVHAGGRTGLGYTYGDVSVASFAHSVLGPVVKGRPVSSPPALWELMGARMRNA FT GRPGVGAMALSAVDVALWDLKARLLGLPLVHLLPAHHDRVPVYGSGGFTNYPLDRLTDQ FT LAGWVRQGIGRVKLKTSRDPEADPRRLTAVRRAVGDGPEVFTDANGALGRKAALYWAHR FT FHDEWDVRWFEEPVASADLEGLRMLRERGPARLEITAGEYAFTAQDFANLTEGPAVDCL FT QADVTRCGGVTGVLEVAGLSAARHLDLSAHCAPAVSAHAFCAVRRLRHLEYFHDHVRVE FT RLLFDGVPSPEGGALRPDTSRPGLGLEVRWADAEPYRVRGVRPPR" FT misc_feature 168970..169935 FT /note="Pfam match to entry PF01188 MR_MLE, Mandelate FT racemase / muconate lactonizing enzyme family, score 73.30, FT E-value 5e-18" FT CDS complement(170052..170456) FT /transl_table=11 FT /gene="SCO7416" FT /gene_synonym="SC6D11.12c" FT /product="hypothetical protein SC6D11.12c." FT /note="SC6D11.12c, unknown, len: 134 aa." FT /db_xref="UniProtKB/TrEMBL:Q9L143" FT /protein_id="CAB76335.1" FT /translation="MWKRKGRKDRRAARPVPMELCDLCARVFPEDEAVTGYVPDSSAVH FT ATNEWFDGLRLITACSDDHFDVIKDGYAHRPFVDEELWAAKLTRALTTGPPALSMDQLG FT CRTGLQEPQIRAAVAWHNERMREAQQRSDP" FT CDS complement(170555..171778) FT /transl_table=11 FT /gene="SCO7417" FT /gene_synonym="SC6D11.13c" FT /product="putative cytochrome P450-family protein." FT /note="SC6D11.13c, possible cytochrome P450-family protein, FT len: 407 aa. Similar to many members of the cytochrome P450 FT family including: Streptomyces griseus SW:CPXH_STRGR FT (EMBL:X63601) cytochrome P450-soy (412 aa), fasta scores FT opt: 673 z-score: 761.0 E():0 35.1% identity in 382 aa FT overlap and Saccharopolyspora erythraea (Streptomyces FT erythraeus) SW:CPXK_SACER (EMBL:M83110) cytochrome P450 FT 107B1 (405 aa), fasta scores opt: 872 z-score: 984.9 E():0 FT 38.4% identity in 409 aa overlap. Contains a Prosite hit to FT PS00086 Cytochrome P450 cysteine heme-iron ligand signature FT and a Pfam match to entry PF00067 p450, Cytochrome P450." FT /db_xref="GOA:Q9L142" FT /db_xref="InterPro:IPR017973" FT /db_xref="PDB:1GWI" FT /db_xref="UniProtKB/TrEMBL:Q9L142" FT /protein_id="CAB76336.1" FT /translation="MTTGTEEARIPLDPFVTDLDGESARLRAAGPLAAVELPGGVPVWA FT VTHHAEAKALLTDPRLVKDINVWGAWRRGEIPADWPLIGLANPGRSMLTVDGAEHRRLR FT TLVAQALTVRRVEHMRGRITELTDRLLDELPADGGVVDLKAAFAYPLPMYVVADLMGIE FT EARLPRLKVLFEKFFSTQTPPEEVVATLTELASIMTDTVAAKRAAPGDDLTSALIQASE FT NGDHLTDAEIVSTLQLMVAAGHETTISLIVNAVVNLSTHPEQRALVLSGEAEWSAVVEE FT TLRFSTPTSHVLIRFAAEDVPVGDRVIPAGDALIVSYGALGRDERAHGPTADRFDLTRT FT SGNRHISFGHGPHVCPGAALSRMEAGVALPALYARFPHLDLAVPAAELRNKPVVTQNDL FT FELPVRLA" FT misc_feature complement(170558..171691) FT /note="Pfam match to entry PF00067 p450, Cytochrome P450, FT score 185.40, E-value 8.8e-52" FT misc_feature complement(170708..170737) FT /note="PS00086 Cytochrome P450 cysteine heme-iron ligand FT signature" FT CDS complement(171775..173016) FT /transl_table=11 FT /gene="SCO7418" FT /gene_synonym="SC6D11.14c" FT /product="putative cytochrome P450-family protein." FT /note="SC6D11.14c, possible cytochrome P450-family protein, FT len: 413 aa. Similar to many members of the cytochrome P450 FT family including: Saccharopolyspora erythraea (Streptomyces FT erythraeus) SW:CPXK_SACER(EMBL:M83110) cytochrome P450 FT 107B1 (405 aa), fasta scores opt: 491 z-score: 571.3 E(): FT 2.1e-24 28.9% identity in 395 aa overlap and Streptomyces FT coelicolor TR:CAB61278(EMBL:AL132991) putative cytochrome FT P450, SCF55.08c (420 aa), fasta scores opt: 1375 z-score: FT 1593.6 E():0 51.7% identity in 404 aa overlap." FT /db_xref="GOA:Q9L141" FT /db_xref="HSSP:1GWI" FT /db_xref="InterPro:IPR002397" FT /db_xref="UniProtKB/TrEMBL:Q9L141" FT /protein_id="CAB76337.1" FT /translation="MSTDAHDVPGAVPLGGPRFQTDPALLYRQMRREHGAVTPVVLDGD FT VPAWLVLGYRELHQVTGDPVLFSRDSDLWNQWENIPDDWPLLPMIGRRQPSILYTVGER FT HRERAAMISDALEAVDPHLLRGHAERFADELVDRLCAKGEADLVGDYAMLLPVRVLARL FT YGFPDEQGPALVTALNDMIDGRERALAGQTHLGTSMARLLADRKAAPADDVASRMLADE FT SGFTEEEVAQDLMVMMAAGHQPTADWIGNSLRLMLTDDRFAASLFGGRNSVAEAMNEVL FT WEDTPTQNVAGRWAARDTQLGGRRIRAGDLVLLGLQGANSDPQVRTDGSALTGGNNAHF FT SFGHGEHRCPFPAQEVAEVIARTGIEVVLDRLPDIDLAVPAGSLTRRPSPWLRGLTELP FT VRFTPTTALGGTSA" FT RBS complement(171788..171792) FT CDS complement(173013..173564) FT /transl_table=11 FT /gene="SCO7419" FT /gene_synonym="SC6D11.15c" FT /gene_synonym="cvnD10" FT /product="putative ATP/GTP binding protein." FT /note="SC6D11.15c, cvnD10, possible ATP/GTP binding FT protein, len: 183 aa. Highly similar to many Streptomyces FT coelicolor putative ATP/GTP binding proteins e.g. FT TR:CAB61279 (EMBL:AL132991) SCF55.09c (178 aa), fasta FT scores opt: 805 z-score: 986.9 E():0 73.7% identity in 167 FT aa overlap and TR:CAB59480 (EMBL:AL132648) SCI41.10c (176 FT aa), fasta scores opt: 645 z-score: 793.2 E():0 61.3% FT identity in 168 aa overlap. Contains a Prosite hit to FT PS00017 ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q9L140" FT /db_xref="InterPro:IPR004130" FT /db_xref="UniProtKB/TrEMBL:Q9L140" FT /protein_id="CAB76338.1" FT /translation="MVVGGFGVGKTTMVRSVSEIRPLNTEETMTQAGEAVDDISEVRGK FT SATTVAFDFGRISLDARNVLYLFGAPGQERFWFLWDRLFSGTLGAVVLVDTRRIDDSWY FT AIDRLEHHGTPFIVACNDFGGPEHSPEAVREALDLDPRVPLVSCDARSRQSSKQVLITL FT VEHLQAHYAGPTARPRQEFA" FT RBS complement(173022..173026) FT misc_feature complement(173532..173555) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(173635..173982) FT /transl_table=11 FT /gene="SCO7420" FT /gene_synonym="SC6D11.16c" FT /gene_synonym="cvnC10" FT /product="hypothetical protein SC6D11.16c." FT /note="SC6D11.16c, cvnC10, unknown, len: 115 aa. Highly FT similar to many proteins of undefined function from FT Streptomyces coelicolor including: TR:CAB61280 FT (EMBL:AL132991) SCF55.10c. (113 aa), fasta scores opt: 407 FT z-score: 530.3 E(): 4.1e-22 63.1% identity in 111 aa FT overlap and TR:Q9X834 (EMBL:AL049727) SC9B1.14C (119 aa), FT fasta scores opt: 249 z-score: 330.7 E(): 5.3e-11 46.2% FT identity in 117 aa overlap." FT /db_xref="InterPro:IPR007995" FT /db_xref="UniProtKB/TrEMBL:Q9L139" FT /protein_id="CAB76339.1" FT /translation="MSRPGRDDAPDRLYTVTQGRSSSGPDNPFDLVTLVVAECAPMPGM FT QSEHTAILRLTEAPTAVVEIAAELRLPVSITKILLSDLHAAGRVSARHPYTAAVPDPDI FT LEQVLVGLRNL" FT CDS complement(173979..174386) FT /transl_table=11 FT /gene="SCO7421" FT /gene_synonym="SC6D11.17c" FT /gene_synonym="cvnB10" FT /product="conserved hypothetical protein SC6D11.17c" FT /note="SC6D11.17c, cvnB10, unknown, len: 135 aa. Highly FT similar to many proteins of undefined function from FT Streptomyces coelicolor including: TR:CAB61281 FT (EMBL:AL132991) SCF55.11c (152 aa), fasta scores opt: 634 FT z-score: 769.3 E():0 71.9% identity in 128 aa overlap and FT TR:Q9X835(EMBL:AL049727) SC9B1.15C (139 aa), fasta scores FT opt: 329 z-score: 407.1 E(): 3e-15 40.9% identity in 132 aa FT overlap" FT /db_xref="InterPro:IPR004942" FT /db_xref="UniProtKB/TrEMBL:Q9L138" FT /protein_id="CAB76340.1" FT /translation="MTGSTTADEKLTWLIEGLLERTPGARHALVLSRDGLKLCRTPELS FT VDQADQLAAIAAGIQSLSHGASVEFGDGSGGVRSAMTEFYGGILFIVEAGEGAHLAVVT FT SEDADAGLVGHHMSELIEQLGEHLTARPRTS" FT CDS complement(174383..176014) FT /transl_table=11 FT /gene="SCO7422" FT /gene_synonym="SC6D11.18c" FT /gene_synonym="cvnA10" FT /product="putative sensor histidine-kinase." FT /note="SC6D11.18c, cvnA10, possible sensor FT histidine-kinase, len: 543 aa. Similar to several from FT Streptomyces coelicolor including: TR:CAB61282 FT (EMBL:AL132991) putative sensor kinase, SCF55.12c (575 aa), FT fasta scores opt: 969 z-score: 843.9 E(): 0 42.9% identity FT in 501 aa overlap and TR:CAB59483 (EMBL:AL132648) putative FT integral membrane protein, SCI41.13c (541 aa), fasta scores FT opt: 630 z-score: 552.6 E(): 2.3e-23 32.9% identity in 559 FT aa overlap. Contains a Pfam match to entry PF00512 signal, FT Histidine kinase and a possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q9L137" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9L137" FT /protein_id="CAB76341.1" FT /translation="MTAPARPGDRPTPRALAAVALPCALVSALVVGGAVAAAPSSVRLP FT LGLGAGAAAILLCAALTAAVHAVRAERATRRLLAAARAEADAERARAAATAERERDALV FT DDFTRERDRLAEQRDREVARLTEETARLGELLKQATGERAAAVSATANAAGRMQALATG FT MLADLRAMEERHSDEAVLADLLHLDHRTAQAGRLADSVAVLTGARSGRRWARPIGMESI FT LRGAMGRIAGYRRVRVHSSSDTAVAGHAAEGVMHALAELLDNAANFSPPTAEIHVYVEE FT VPAGVIVSVEDSGLVMGEVQLRRAQQAVAGETAGLGGLTGTRLGLAVVGRLAAKYGLKV FT SFRPSARGGTGVLMLVPQDILSGPALPAAPGATPAATPAEVRDDRRYTPEPPAAEPAPA FT EAAPEPPPVHDLADQDQDQDQDQDQDRDQAPRDRDRHGQDRDRDQEPEPDREPDPSAEE FT LLPKRRRGRTLAAAERARAAARSAEPRATPSADDAKVRAARFSSFRQAVRTTTCATTTG FT AAAEPAETAPDLPSHSSAHPEGDTTP" FT misc_feature complement(174944..175531) FT /note="Pfam match to entry PF00512 signal, Histidine FT kinase, score -40.20, E-value 0.0075" FT CDS complement(176152..176862) FT /transl_table=11 FT /gene="SCO7423" FT /gene_synonym="SC6D11.19c" FT /product="conserved hypothetical protein SC6D11.19c." FT /note="SC6D11.19c, unknown, len: 236 aa. Weakly similar to FT a protein of undefined function from Rhodococcus FT rhodochrous plasmid pKA22 TR:Q9XBN0(EMBL:AF165152) FT hypothetical 25.4 KD protein (242 aa), fasta scores opt: FT 336 z-score: 419.4 E(): 6.1e-16 33.0% identity in 209 aa FT overlap." FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9L136" FT /protein_id="CAB76342.1" FT /translation="MDDWRRFAQQMASLARDLLSQESLHDTLDRITASATELVEDCDAA FT GILILRGTKVQSLAPTEQVVIDSDALQGRVGEGPCFDAARSGTGERQFRIADFTDEAQR FT WPKYVPEARKLNLGSMMGFLLFTEDEDLGALNMYSYRPGAFTEADETAGWLLASHAAVA FT FSSARTHAQMQEAIGTRHIIGEAMGILMGRHRMSEDQAFAALRRYSQDHNVKLRNVAAQ FT VCERGGLPEPTDKR" FT RBS complement(176870..176874) FT CDS 176961..177428 FT /transl_table=11 FT /gene="SCO7424" FT /gene_synonym="SC6D11.20" FT /product="putative MarR-family transcriptional regulator" FT /note="SC6D11.20, possible MarR-family transcriptional FT regulator, len: 155 aa. Weakly similar to Streptomyces FT coelicolor TR:CAB56677 (EMBL:AL121596) MarR-family protein, FT SCF51A.25 (148 aa), fasta scores opt: 209 z-score: 254.7 FT E(): 9.1e-07 33.1% identity in 124 aa overlap. Contains a FT Pfam match to entry PF01047 MarR, MarR family with the FT putative helix-turn-helix motif situated between residues FT 53..74 (+4.29 SD)." FT /db_xref="GOA:Q9L135" FT /db_xref="InterPro:IPR000835" FT /db_xref="UniProtKB/TrEMBL:Q9L135" FT /protein_id="CAB76343.1" FT /translation="MHHALMDTSPEGPDDLIVAVEQMIRYVRQSARTGGLSTAASSTLA FT RLSREGPQRLTELARAEGVSQPNMTQLVTRLERAGLARRTADASDGRGVLVAVTSTGAE FT VLDRRRAERARALRQLMEDMTGPERQATTTALLALARVIDNRQDTSEEGRA" FT misc_feature 177066..177377 FT /note="Pfam match to entry PF01047 MarR, MarR family, score FT 79.60, E-value 6.3e-20" FT RBS 177410..177414 FT CDS 177425..179158 FT /transl_table=11 FT /gene="SCO7425" FT /gene_synonym="SC6D11.21" FT /product="putative multidrug-efflux transporter protein." FT /note="SC6D11.21, possible multidrug-efflux transporter FT protein, len: 577 aa. Highly similar to several including: FT Streptomyces virginiae TR:Q9XE01(EMBL:AB019519) FT virginiamycin S resistance protein, VarS (518 aa), fasta FT scores opt: 322 z-score: 328.6 E(): 7e-11 25.7% identity in FT 536 aa overlap and Deinococcus radiodurans FT TR:AAF11851(EMBL:AE002062) multidrug-efflux transporter, FT putative (410 aa), fasta scores opt: 937 z-score: 945.6 FT E(): 0 41.3% identity in 395 aa overlap. Contains a Pfam FT match to entry PF00083 sugar_tr, Sugar (and other) FT transporter and multiple possible membrane spanning FT hydrophobic domains." FT /db_xref="GOA:Q9L134" FT /db_xref="InterPro:IPR006016" FT /db_xref="UniProtKB/TrEMBL:Q9L134" FT /protein_id="CAB76344.1" FT /translation="MSAPRGKAASQAASPFRQPKAVWAVAFACVISFMGIGLVDPILPA FT LAESLDVTPSQVSLLFSSYLIVTAVAMLVVGWVSSRIGAKRTLVTGLAVIVVFAALAGA FT TGSINGIVGFRAGWGLGNALFIATSLAVIVASASGGFSGAIILYETALGLGIAVGPLLG FT GELGGISWRGPFFGVAALMAVALIATLAFVPDLPRPEKVTSPLAPLKALRHRGLLTLGI FT MALLYNWGFFTMLGYAPYPMELDAHELGLVFTGWGLLVAAFSVFFAPRLQARYGTAPVL FT YANLLGLAVVMAVIAAGVTDPTTVIVAVVVSGAFIGINNTLTTQAVMLVSPVERPVASS FT AYGFLRFIGGGLAPYVAGKLADATDLSVPFYLGAATFLLAVPVLASGHRLLRRAETDTG FT EGEPLTPALTPVGSPAATDAPPVVVAVGAHREAAAVVDTAARLARDTASPLEVVHVRRT FT AVVEEQAADTETDEQAKAAVTAHLDRLGGMGVTATGQILTGVGDHAAAGRALARHAAEV FT GARTVAVGRSPRGPLAQFADGSFTSALTHAATCTVVLVDPNAEPRPLTPRSLTELRAEA FT R" FT misc_feature 177485..178624 FT /note="Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter, score -98.80, E-value 0.0024" FT CDS complement(179248..179685) FT /transl_table=11 FT /gene="SCO7426" FT /gene_synonym="SC6D11.22c" FT /product="hypothetical protein SC6D11.22c." FT /note="SC6D11.22c, unknown, len: 145 aa." FT /db_xref="UniProtKB/TrEMBL:Q9L133" FT /protein_id="CAB76345.1" FT /translation="MAAEDGGSPGTAGPPLPRVLCDTAELLSLGGDAPAGALWKLAEPG FT RQLDANVVRLPAGGRVDTHTEPDLDVLLLVLEGAARLDSSDGEHPLRAGVLTWLPHGST FT RAVLAGPDGVTYLTVHRRRPGMRIQPPEAADRLRRSLGGDA" FT CDS 179835..180281 FT /transl_table=11 FT /gene="SCO7427" FT /gene_synonym="SC6D11.23" FT /product="Conserved hypothetical protein SC6D11.23." FT /note="SC6D11.23, unknown, len: 148 aa. Similar to several FT proteins of undefined function e.g. Vibrio parahaemolyticus FT SW:YJEB_VIBPA(EMBL:U09005) hypothetical 15.6 KD protein FT (141 aa), fasta scores opt: 292 z-score: 356.7 E(): 1.9e-12 FT 39.7% identity in 146 aa overlap." FT /db_xref="GOA:Q9L132" FT /db_xref="InterPro:IPR000944" FT /db_xref="UniProtKB/Swiss-Prot:Q9L132" FT /protein_id="CAB76346.1" FT /translation="MRLTKFTDLALRSLMRLAVVRDGDEPLATREVAEVVGVPYTHAAK FT AITRLQHLGVVEARRGRGGGLTLTDLGRRVSVGWLVRELEGEAEVVDCEGDNPCPLRGA FT CRLRRALRDAQEAFYAALDPLTVTDLVAAPTGPVLLGLTDRPSG" FT RBS 180345..180349 FT misc_feature 180355..180777 FT /note="Pfam match to entry PF00042 globin, Globin, score FT 55.10, E-value 1.6e-14" FT CDS 180355..181551 FT /transl_table=11 FT /gene="SCO7428" FT /gene_synonym="hmpA1" FT /product="flavohemoprotein" FT /note="SC6D11.24, hmpA1, possible flavohemoprotein, len: FT 398 aa. Highly similar to many protein of the FT flavohemoprotein subfamily, including: Escherichia coli FT SW:HMPA_ECOLI(EMBL:X58872) flavohemoprotein FT (hemoglobin-like protein) (396 aa), fasta scores: opt: 826 FT z-score: 935.2 E():0 39.4% identity in 404 aa overlap and FT Erwinia chrysanthemi SW:HMPA_ERWCH (EMBL:X75893) FT flavohemoprotein (395 aa), fasta scores: opt: 761 z-score: FT 862.0 E():0 35.9% identity in 404 aa overlap. Contains Pfam FT matches to entries Pfam match to entry PF00042 globin, FT Globin and Pfam match to entry PF00175 oxidored_fad, FT Oxidoreductase FAD/NAD-binding domain." FT /db_xref="GOA:Q9L131" FT /db_xref="HSSP:1CQX" FT /db_xref="InterPro:IPR017927" FT /db_xref="UniProtKB/TrEMBL:Q9L131" FT /protein_id="CAB76347.1" FT /translation="MLSEQSVPVVRATLPAVGAAIGDIAALFYRKLFDAHPELLRDLFN FT RGNQANGEQQRALAGSVAAFAGLLLENPDERADVLLSRISHKHASLGITPDQYTIVHRH FT LMAAVVDVLGDAVTPEVARAWDEVYWLMANALIALEARLYTEKGVAEGDVWRTMEIVDR FT VEESADAVSLVLGSADGRPVVPFRPGQYVSVQVELADGARQIRQYSLSAAPGRSDWRIT FT VKRVRGDGQPDGEVSSWLYANARKGDALNVSLPAGDLALAEHDGPLLLVSAGIGVTPML FT SMLDHLAAAGATRPVTVVHADRTPDHHAHRQEQLDLIRTLPGARLHLWYEEPGDRAPEA FT STGRADLTGLDLPADLTVYLCGPVPFMRAVRGDLLRRGVPAEAIHYEVFGPDLWLGQQ" FT misc_feature 181147..181476 FT /note="Pfam match to entry PF00175 oxidored_fad, FT Oxidoreductase FAD/NAD-binding domain, score 51.20, E-value FT 2.3e-11" FT CDS complement(181600..181950) FT /transl_table=11 FT /gene="SCO7429" FT /gene_synonym="SC6D11.25c" FT /product="hypothetical protein SC6D11.25c." FT /note="SC6D11.25c, unknown, len: 116 aa." FT /db_xref="UniProtKB/TrEMBL:Q9L130" FT /protein_id="CAB76348.1" FT /translation="MLSHTLEHGVLVITVDQDPGIAGRATLTTHITNLVDAHQPTPVVI FT VLTERAGGHAAVSAVLRAHQWCGRLGVLMSVVTHSAPVRRLLEANADSSGPRLVVHARV FT DTAISTAFTAAA" FT RBS complement(181956..181960) FT CDS 182126..182812 FT /transl_table=11 FT /gene="SCO7430" FT /gene_synonym="SC6D11.26" FT /product="hypothetical protein SC6D11.26." FT /note="SC6D11.26, unknown, len: 228 aa. Contains a Pfam FT match to entry PF01955 DUF105, Domain of unknown function." FT /db_xref="InterPro:IPR002808" FT /db_xref="UniProtKB/TrEMBL:Q9L129" FT /protein_id="CAB76349.1" FT /translation="MPALLPPPRTGADRLLDPDDLIRVEDGERLHALLWRPGPGWRMVS FT SAVLGGGTGERAWVLNAQVAHGYRRTDPARHLAELARAAGARGPGVGLMTAADVSAHGR FT ARDGGAEAVATAGISVRGWAAAPQEGTAGAGPPGTINIVAALPVALSDAALVNAVMTAT FT EAKVQALLDAGLDCSGTPTDAVCVAARAPVGEAEVHAFAGPRSEWGARLARAVHRAVGA FT ALPTAP" FT misc_feature 182168..182806 FT /note="Pfam match to entry PF01955 DUF105, Domain of FT unknown function, score 47.10, E-value 4e-10" FT CDS complement(182832..183092) FT /transl_table=11 FT /gene="SCO7431" FT /gene_synonym="SC6D11.27c" FT /product="putative integral membrane protein." FT /note="SC6D11.27c, possible integral membrane protein, len: FT 86 aa. Contains possible membrane spanning hydrophobic FT domains." FT /db_xref="UniProtKB/TrEMBL:Q9L128" FT /protein_id="CAB76350.1" FT /translation="MDERKAPVDDGLGDLEPGTRQRTQLRVRVADIAWTAACAVLALWA FT VWTAIDLARGATAWAYCAVAWLLLAVALTVRVMAVRRRTSL" FT CDS complement(183226..183909) FT /transl_table=11 FT /gene="SCO7432" FT /gene_synonym="mprA2" FT /product="secreted extracellular small neutral protease." FT /note="SC6D11.28c, mprA2, secreted extracellular small FT neutral protease (EC 3.4.24.-), len: 227 aa. Identical to FT Streptomyces lividans SW:SNPA_STRLI(EMBL:M81703) FT extracellular small neutral protease precursor, SnpA (227 FT aa), fasta scores opt: 1483 z-score: 1546.5 E(): 0 100.0% FT identity in 227 aa overlap. Also highly similar to FT Streptomyces coelicolor SW:SNPA_STRCO(EMBL:Z11929) FT extracellular small neutral protease precursor, MprA (215 FT aa), fasta scores opt: 854 z-score: 896.8 E():0 65.6% FT identity in 218 aa overlap. Contains a possible N-terminal FT signal sequence." FT /db_xref="GOA:P0A3Z7" FT /db_xref="HSSP:1C7K" FT /db_xref="InterPro:IPR000013" FT /db_xref="UniProtKB/Swiss-Prot:P0A3Z7" FT /protein_id="CAB76351.1" FT /translation="MRITLPLLSTAVGLGLTAAVLGTGPAATAAAPQEPVRAAQLGYQP FT SAGSGEDAAANRAFFEAVVKSVAEKRAANPSAAAAVTVYYSATNAPSFRSQISRSAQIW FT NSSVSNVRLAESSSGADFAYYEGNDSRGSYASTDGHGSGYIFLDYRQNQQYDSTRVTAH FT ETGHVLGLPDHYSGPCSELMSGGGPGPSCTNPYPNSTERSRVNQLWAYGFQAALDKALE FT KASQR" FT CDS 184125..185111 FT /transl_table=11 FT /gene="SCO7433" FT /gene_synonym="mprR2" FT /product="small neutral protease regulatory protein." FT /note="SC6D11.29, mprR2, small neutral protease regulatory FT protein, len: 328 aa. Almost identical to Streptomyces FT lividans SW:SNPR_STRLI (EMBL:M81703) small neutral protease FT regulatory protein (344 aa), fasta scores opt: 2123 FT z-score: 2481.6 E(): 0 98.5% identity in 327 aa overlap. FT Also highly similar to Streptomyces coelicolor FT SW:MPRR_STRCO (EMBL:Z11929) small neutral protease FT regulatory protein, MprR (316 aa), fasta scores opt: 1163 FT z-score: 1362.7 E():0 60.7% identity in 323 aa overlap. FT Contains a Prosite hit to PS00044 Bacterial regulatory FT proteins, lysR family signature and a Pfam match to entry FT PF00126 HTH_1, Bacterial regulatory helix-turn-helix FT protein, lysR family with the putative helix-turn-helix FT motif situated between residues 18..39 (+4.38 SD)." FT /db_xref="GOA:Q9L127" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/Swiss-Prot:Q9L127" FT /protein_id="CAB76352.1" FT /translation="MELEVRHLRALCAIADAGSLHRAARRLGVAQPTLSTQLTRIEQAL FT GGPLFTRERTGCRPTPLGRTVLGRARPLLTDMNTLVREARAAAAGGDSRLRVGSTASRA FT LAGWLRRLRRPGLEPTLQMDVSANALLRRVTDGQLDVAFVHEVEGCALHIPEDLRLRVL FT VEREPQFVMLPADHPAAARPVVRLADLADDRWMVDPTVDGEWDGVHRMLRAVGLNPRVL FT HGDYHTAASLVATGEVVTVCQPSSQSRPDTAVRRLYGDPLGVRLLLAARTRAELDAVFP FT ALEDAYWEAARQSTAYREWLEGGGIRTLPRCPVAATGGGRVEFVRAR" FT misc_feature 184137..184553 FT /note="Pfam match to entry PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix protein, lysR family, score FT 132.40, E-value 8.2e-36" FT misc_feature 184179..184271 FT /note="PS00044 Bacterial regulatory proteins, lysR family FT signature" FT CDS 185219..185980 FT /transl_table=11 FT /gene="SCO7434" FT /gene_synonym="SC6D11.30" FT /product="putative lipoprotein." FT /note="SC6D11.30, possible lipoprotein, len: 253 aa. FT Contains a possible N-terminal signal sequence and an FT appropriately positioned Prosite hit to PS00013 Prokaryotic FT membrane lipoprotein lipid attachment site." FT /db_xref="GOA:Q9L126" FT /db_xref="InterPro:IPR005075" FT /db_xref="UniProtKB/TrEMBL:Q9L126" FT /protein_id="CAB76353.1" FT /translation="MSSARRLPPLRSLAVVGALGASALLLTACTNADTTRSSVAEAAQT FT ESPSPTGTDTQSPSPTGSPSMNEDQTERKDLVSAMKVTWDKAADTAVKEVPEGKLVDLE FT LKRVKADATASPTGSPTGTASPSMPNPAPSEGAPEWEAKVAQSDGTLHRIDIDAVNGKV FT FRTMVDPDQDPDDKTQVTEWLDKAKQTPEQAVKAATAKAKGTVTHVELGDNDDQQVVWG FT VDVVDKSNWNKTTVTVDAANGKVLGQKVDKD" FT misc_feature 185273..185305 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(186054..187322) FT /transl_table=11 FT /gene="SCO7435" FT /gene_synonym="SC6D11.31c" FT /product="putative transmembrane transport protein." FT /note="SC6D11.31c, possible transmembrane transport FT protein, len: 422 aa. Similar to many transport proteins FT e.g. Acinetobacter sp. TR:O30513(EMBL:AF009224) benzoate FT transport protein, BenK (466 aa), fasta scores opt: 423 FT z-score: 455.2 E(): 6.2e-18 31.1% identity in 421 aa FT overlap. Contains a Prosite hit to PS00216 Sugar transport FT proteins signature 1 and a Pfam match to entry PF00083 FT sugar_tr, Sugar (and other) transporter. Contains multiple FT possible membrane spanning hydrophobic domains." FT /db_xref="GOA:Q9L125" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9L125" FT /protein_id="CAB76354.1" FT /translation="MASTTTSGTPAQTGRAVGGTWTVILCWITVLLEGYDLVVLGAIIP FT TLLKTHHLGMTAGDATTIATLSLVGVAIGAVCVGPLADRLGRRRLLIGSVVLFSVLTVV FT VPLANSVAMFAALRLLAGLGLGACMPVSLTMMAEHMPASRRARASTLTMTGYHTGAVIT FT SLLALQVTDNWEILFYLLGVVGLVIAAIQWFKLPESAAFERARRDGAQRVPFTELLKPA FT YLRAGIGIWVASFMGLLLVYGLNTWLPKLMNDAGYPVPTAVTQLLVLNIGGVVGLVLGG FT YVADRRGIKGTTMVWFAVSVLMLGCLSVKMASDLLLNVVVFFTGVFVFSAMVLVYAYVT FT HFYPASVRGTALGSASGIGRIGSIVGPSITGALVASGVGHPWGFYFFAAVAVLGFLAVL FT TLPRGGAEPAGAAAAAPPAAPAG" FT misc_feature complement(186090..187262) FT /note="Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter, score 51.00, E-value 2.7e-11" FT misc_feature complement(187041..187091) FT /note="PS00216 Sugar transport proteins signature 1" FT CDS complement(187413..188867) FT /transl_table=11 FT /gene="SCO7436" FT /gene_synonym="SC6D11.32c" FT /product="probable aldehyde dehydrogenase." FT /note="SC6D11.32c, probable aldehyde dehydrogenase, len: FT 484 aa. Highly similar to many dehydrogenases including: FT Pseudomonas putida SW:XYLC_PSEPU(EMBL:U15151) benzaldehyde FT dehydrogenase [NAD+] (EC 1.2.1.28) (487 aa), fasta scores FT opt: 1519 z-score: 1634.7 E():0 47.6% identity in 483 aa FT overlap and Streptomyces coelicolor FT TR:Q9X8J9(EMBL:AL049841) putative aldehyde dehydrogenase, FT SCE9.27C (486 aa), fasta scores opt: 1215 z-score: 1308.5 FT E():0 43.1% identity in 476 aa overlap. Contains a Prosite FT hit to PS00687 Aldehyde dehydrogenases glutamic acid active FT site and a Pfam match to entry PF00171 aldedh, Aldehyde FT dehydrogenase family." FT /db_xref="GOA:Q9L124" FT /db_xref="HSSP:1EUH" FT /db_xref="InterPro:IPR016162" FT /db_xref="UniProtKB/TrEMBL:Q9L124" FT /protein_id="CAB76355.1" FT /translation="MTLLDSAVWGGKFSSDGWQGSPTEQPVTEPATGDRLGTVGLASAE FT DVNRAAARAAEAQRTWAATSPQRRAAVLRRAGELFTEHAAEIEDWLVREAGSVRSKAAF FT EAGLAIGECFECAGLPTHPQGEVLTSEDARWSLARRRPAGVVSVIAPFNFPLILGLRSV FT APALALGNSVLLKPDPRTAVSGGVVIARIFEEAGLPAGVLHLLPGDGSVGRAVVEAPEV FT RVISFTGSTPVGRAIGEQAGRLLKRAHLELGGNNALVVLPGADVAKAASAGAFGSYLHQ FT GQICMTTGRHIVHESLVEEYTAALAAKAEALPVGDPAREDVALGPIIDRRQLERVHGIV FT TDSVAAGAKVAAGGEIDGAGYRATVLTGLTTDMPAWREEIFGPVAPVISFATTEEAARI FT VNDCEYGLSVGILGDVGTAMKLADRIDSGKVHINEQTVSDEPNAPFGGVKASGTGSRFG FT GAAANVEAFTETQWLTVRPDIADYPF" FT misc_feature complement(187437..188819) FT /note="Pfam match to entry PF00171 aldedh, Aldehyde FT dehydrogenase family, score 475.80, E-value 3.5e-139" FT misc_feature complement(188097..188120) FT /note="PS00687 Aldehyde dehydrogenases glutamic acid active FT site" FT CDS complement(188914..190494) FT /transl_table=11 FT /gene="SCO7437" FT /gene_synonym="SC6D11.33c" FT /product="putative decarboxylase." FT /note="SC6D11.33c, possible decarboxylase, len: 526 aa. FT Similar to many thiamine pyrophosphate requiring enzymes. FT Highly similar to Pseudomonas putida FT SW:MDLC_PSEPU(EMBL:J05293) benzoylformate decarboxylase (EC FT 4.1.1.7) MdlC (528 aa), fasta scores opt: 1829 z-score: FT 1915.9 E(): 0 52.6% identity in 521 aa overlap. Also FT similar to Escherichia coli SW:ILVB_ECOLI(EMBL:J01633) FT acetolactate synthase isozyme I large subunit (EC 4.1.3.18) FT (562 aa), fasta scores opt: 495 z-score: 520.7 E(): 1.4e-21 FT 26.0% identity in 523 aa overlap. Contains a Prosite hit to FT PS00187 Thiamine pyrophosphate enzymes signature and a Pfam FT match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate FT enzymes." FT /db_xref="GOA:Q9L123" FT /db_xref="HSSP:1BFD" FT /db_xref="InterPro:IPR012000" FT /db_xref="UniProtKB/TrEMBL:Q9L123" FT /protein_id="CAB76356.1" FT /translation="MPSVRRVSHEFLERQGLTTVFGNPGSNELPFLAGLPDGFRYVLGL FT HEGAVVGMADGYAQATGRPVLVNLHAASGSGNAMGALTNAVASRTPLVVVAGQQVRPAI FT GPEANLASVDAPALMKPLVGWAAEPACAGDVPRALAQAVFEARLQRRPTYLSVPYDDWS FT ADVDDNALAVLDRRVLRAAVPGGEQRRWLVEQVASARRPALVLGGDIDSAGRFDDAVRL FT AERLGGPVWAAPSQFRLPFPNRHPLFRGVLPAGIAPVSAAFEGHDLVLVLGAPVFRYHE FT HLPGRYLPEGTRLIQVTEDASAAARAPMGEALVADPGAVIDVLLEALGAADRPAGPYRP FT VPEPLTAEGPALHPEQVFAALREEMPEDTAYVVESTSTNAAWWRQTDLRRQGSYYFPAA FT GGLGFGLPGAVGVAMAQPGRPVVGVIGDGSANYGITALWTAAQHRVPLTVVLLRNGAYG FT ALRWFGGLLGVPDAPGLDIPDLDFTRIAEGYGVRAQHVGSVAELRAALAETPEHPRLIQ FT VDTALTTPS" FT misc_feature complement(188941..190461) FT /note="Pfam match to entry PF00205 TPP_enzymes, Thiamine FT pyrophosphate enzymes, score 270.60, E-value 1.7e-83" FT misc_feature complement(189208..189267) FT /note="PS00187 Thiamine pyrophosphate enzymes signature" FT CDS 190589..191524 FT /transl_table=11 FT /gene="SCO7438" FT /gene_synonym="SC6D11.34" FT /product="putative LysR-family transcriptional regulatory FT protein." FT /note="SC6D11.34, possible LysR-family transcriptional FT regulatory protein, len: 311 aa. Similar to many FT LysR-family regulators involved in the control of FT nodulation e.g. Rhizobium sp. (strain NGR234) FT SW:NOD1_RHISN(EMBL:AE000065) nodulation protein D I (322 FT aa), fasta scores opt: 449 z-score: 537.5 E(): 1.6e-22 FT 32.3% identity in 294 aa overlap. Contains a Prosite hit to FT PS00044 Bacterial regulatory proteins, lysR family FT signature and Pfam matches to PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix protein, lysR family and Pfam FT match to entry PF01046 NodD_C_term, NodD transcription FT activator carboxyl terminal region. The putative FT helix-turn-helix motif situated between residues 19..40 FT (+4.28 SD)." FT /db_xref="GOA:Q9L122" FT /db_xref="InterPro:IPR005119" FT /db_xref="UniProtKB/TrEMBL:Q9L122" FT /protein_id="CAB76357.1" FT /translation="MGTFDLNLARVFVLLYETGSVTATAETLHVTQPTVSYSLGKLRRH FT FDDELFRRNGRGLTPTAGARRLYLPLQRALAEIDGTVRQGDLFDAGSMSGRFTIALSDL FT GEATLLPRLVATARERAPGVSFTVRPFDVEDAEGQLRRGDLDAFVATPVITSHLTVRIP FT LFRERYVLMVAADHPRVRGDAVTPEDLAAEHHATVFGPSGHVTPRALLGAHGLLERVAV FT DATRFSMLPYLLEQTDLVAIVPEYVGEVFTASHRVRLVRLPFETEPIEIALYARHESSR FT SPAQRWLVQFMAEVLGEQVSPAQLPPSSRR" FT misc_feature 190604..191035 FT /note="Pfam match to entry PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix protein, lysR family, score FT 128.70, E-value 1.1e-34" FT misc_feature 190646..190738 FT /note="PS00044 Bacterial regulatory proteins, lysR family FT signature" FT misc_feature 191039..191482 FT /note="Pfam match to entry PF01046 NodD_C_term, NodD FT transcription activator carboxyl terminal region, score FT 25.40, E-value 2e-06" FT CDS 191535..192275 FT /transl_table=11 FT /gene="SCO7439" FT /gene_synonym="SC6D11.35" FT /product="conserved hypothetical protein" FT /note="SC6D11.35, unknown, len: 246 aa. Weakly similar to a FT protein of undefined function from Bacillus subtilis FT TR:P71089(EMBL:Z82044) (251 aa), fasta scores opt: 424 FT z-score: 507.0 E(): 8e-21 35.4% identity in 209 aa FT overlap" FT /db_xref="GOA:Q9L121" FT /db_xref="InterPro:IPR005320" FT /db_xref="UniProtKB/TrEMBL:Q9L121" FT /protein_id="CAB76358.1" FT /translation="MTAPQPTILATSGGHRAGGRTMVAFDALVHHAVDLSGAHGRRPRV FT LYVGTAIGDAEHFTARMTEAARVAGFDLTPLHLFPMPNVEDVEETVLAQDVVWVMGGSV FT ANLLAVWRVHGLDRVMRKAWEAGVVLSGVSAGSLCWFRGGATDSFGPELRPITDALDFL FT PYGNGVHYDVDPGRRPLIHRLVADGTLPTAHCTDDGVGLVYRGTELAEAVTEVPGKGAY FT VVARDGDTAVEERIEPRELPGPGR" FT CDS complement(192317..193261) FT /transl_table=11 FT /gene="SCO7440" FT /gene_synonym="SC6D11.36c" FT /product="putative hydrolase" FT /note="SC6D11.36c, possible hydrolase, len: 314 aa. Similar FT to several including Moraxella sp. SW:DEH1_MORSP FT (EMBL:D90422) haloacetate dehalogenase H-1 (EC 3.8.1.3) FT (294 aa). fasta scores opt: 356 z-score: 414.9 E(): FT 1.1e-15 27.9% identity in 297 aa overlap and Streptomyces FT coelicolor TR:O86546 (EMBL:AL031350) putative hydrolase, FT SC1F2.09C (309 aa), fasta scores opt: 498 z-score: 577.2 FT E(): 9.9e-25 35.2% identity in 307 aa overlap. Contains a FT Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold." FT /db_xref="GOA:Q9L120" FT /db_xref="HSSP:1EHY" FT /db_xref="InterPro:IPR000639" FT /db_xref="UniProtKB/TrEMBL:Q9L120" FT /protein_id="CAB76359.1" FT /translation="MTDDATAPSSSCDQNPVPGLPLHDLAGFTHRWVDAEGIRLHAVEG FT GRPAGPTVVLLAGFPQTWWAWRKVMPGLAARFRVIAIDLPGQGHSERPRGGYDTHTVAS FT RVQTALTALDVPKYWLVGHDVGAWVAFSLALKYEERLHGVALLDAGIPGITLPDSIPTD FT PDRAWKTWHFAFHLVPELPETLLTGRERDYVDWFLKVKTLSPDTFDGAEIDHYAAAVAA FT EGGLSASLAYYRDAAESARRNHDALERGHLTVPVLGVSGSHGSIPDMAASIGPWAANAT FT GAVIPQAGHFIPDEQPEATVKVLTAFIDYERAE" FT misc_feature complement(192338..193033) FT /note="Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold, score 61.80, E-value 1.5e-14" FT CDS 193348..193941 FT /transl_table=11 FT /gene="SCO7441" FT /gene_synonym="SC6D11.37" FT /product="putative transcriptional regulatory protein" FT /note="SC6D11.37, possible transcriptional regulatory FT protein, len: 197 aa. Similar to several putative FT regulators e.g. Streptomyces lividans FT TR:O85695(EMBL:AF072709) putative transcriptional regulator FT (192 aa), fasta scores opt: 170 z-score: 212.6 E(): 0.0002 FT 29.7% identity in 192 aa overlap. Contains a possible FT helix-turn-helix motif situated between residues 29..50 FT (+3.58 SD)." FT /db_xref="GOA:Q9L119" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9L119" FT /protein_id="CAB76360.1" FT /translation="MMAGKKQFDVDTALDAAMVQYWRAGYADTSLDDLSRATGLNRSSL FT YSSFGDKESLYLRCLDRYAARYGSRYDHALSRASEEPLRAVRAFFEVTLERIADPDVPD FT GCLIAQTAMAAPVLGPAIAARAVEALGLQRARLRTALDAARLAEDEADDFAVHMTAVNQ FT SLAVMSRTGASRQQLRTVVDISMSALSRALPARS" FT CDS 194100..194564 FT /transl_table=11 FT /gene="SCO7442" FT /gene_synonym="SC6D11.38" FT /product="hypothetical protein SC6D11.38." FT /note="SC6D11.38, unknown, len: 154 aa. Rich in the amino FT acid Ala." FT /db_xref="UniProtKB/TrEMBL:Q9L118" FT /protein_id="CAB76361.1" FT /translation="MFATAVRGKAVSMSDPNKDTNKKPTSTRTAESKARGAAEQATAPA FT ARAGQAAAGKASEAATTAKAGAQRSVDAANGAVQTAAKSVAAGRQAVVTTSEQVAATAK FT TAWTVVAQRKLVAAGVGAGLTALSAASYAVGRRAGRHAHGPLTRLTGGRI" FT RBS 194639..194643 FT CDS 194653..196293 FT /transl_table=11 FT /gene="SCO7443" FT /gene_synonym="pgm" FT /product="phosphoglucomutase." FT /note="SC6D11.39, pgm, phosphoglucomutase (EC 5.4.2.2), FT len: 546 aa. Highly similar to many phosphoglucomutases FT e.g. Escherichia coli SW:PGMU_ECOLI(EMBL:U08369) FT phosphoglucomutase (EC 5.4.2.2) (546 aa), fasta scores opt: FT 2216 z-score: 2396.0 E():0 60.8% identity in 538 aa FT overlap. Contains a Prosite hit to PS00710 FT Phosphoglucomutase and phosphomannomutase phosphoserine FT signature and a Pfam match to entry PF00408 PGM_PMM, FT Phosphoglucomutase/phosphomannomutase." FT /db_xref="GOA:Q9L117" FT /db_xref="InterPro:IPR016066" FT /db_xref="UniProtKB/TrEMBL:Q9L117" FT /protein_id="CAB76362.1" FT /translation="MQHDRAGRPAGPEDLIDVARLVTAYYALHPDPGEPAQRVAFGTSG FT HRGSSLVAAFNDDHIAATSQAICEYRSAQGTDGPLFLGADTHALSEPARVTALEVFAAN FT DVTVLIDSADGYTPTPAVSHAILTHNRGRTSGLADGVVVTPSHNPPADGGFKYNPPNGG FT PAGSDATSWIQDRANEIIAAGLKDVRRIPYARALAAPGTGRHDFLDAYVRDLPSVLDLD FT AIRSAGVRIGADPLGGASVAYWGRIAEQHRLDLTVVNPLADPTWRFMTLDWDGKIRMDC FT SSPHAMASLIQGRDRFDIATGNDADADRHGIVTPDAGLMNPNHYLATAIAYLYAHRADW FT PAGAGVGKTLVSSGMIDRVAADLGRRLVEVPVGFKWFVDGLVDGSLGFGGEESAGASFL FT RRDGSVWTTDKDGIILALLASEITAVTGKTPSEHYAALTARFGDPAYARIDAPATREEK FT ARLARLSPAQVTADTLAGEPVTAVLTEAPGNGAPIGGIKVTTENAWFAARPSGTEDVYK FT IYGESFLGADHLRQVQDEAKLVVLGALGG" FT misc_feature 194761..196203 FT /note="Pfam match to entry PF00408 PGM_PMM, FT Phosphoglucomutase/phosphomannomutase, score 391.10, FT E-value 1.1e-113" FT misc_feature 195070..195114 FT /note="PS00710 Phosphoglucomutase and phosphomannomutase FT phosphoserine signature" FT CDS complement(196333..197604) FT /transl_table=11 FT /gene="SCO7444" FT /gene_synonym="SC5C11.01c" FT /gene_synonym="SC6D11.40c" FT /product="putative cytochrome P450 (fragment)." FT /note="SC5C11.01c, possible cytochrome P450, partial CDS, FT len:> 40 aa. This CDS forms the N-terminus of SC6D11.40c, FT carried on the adjoining cosmid, which is weakly similar to FT many cytochrome P450's. This similarity is lost in this FT portion of the predicted protein." FT /note="SC6D11.40c, possible cytochrome P450, partial CDS, FT len:> 421 aa. Weakly similar to many cytochrome P450's FT including: Saccharopolyspora erythraea (Streptomyces FT erythraeus) SW:CPXQ_SACER(EMBL:U82823) cytochrome P450 FT 113A1 (erythromycin B/D C-12 hydroxylase) (397 aa), opt: FT 259 z-score: 300.0 E(): 2.7e-09 30.5% identity in 361 aa FT overlap. Overlaps and extends into CDS SC5C11.01c on the FT adjoining cosmid. Contains a Prosite hit to PS00086 FT Cytochrome P450 cysteine heme-iron ligand signature and a FT Pfam match to entry PF00067 p450, Cytochrome P450." FT /db_xref="GOA:Q8CJK0" FT /db_xref="InterPro:IPR017972" FT /db_xref="UniProtKB/TrEMBL:Q8CJK0" FT /protein_id="CAD55402.1" FT /translation="MADPGDHVVEPGGRRGRTAGVGGGHVVQDGRVSARKADRGRAGPA FT CPVDRAADGTWRVHDFAVARALLRGPGTVQAGLGIETVEKLPPRVRRPVLYRDGPEHRE FT HRRQTARYFTPRRVDEHYREPMVRIAEEQLAVLRSAGEAPLSDLAFGLAVGVVSEVVGL FT RYSRPGIRRRLERFFPEEFGEPGLTSVRGLYWLVRQNTNWLRIHLADVRPAVRAHRRRE FT HDDLISHLIAEGCSDVEILGECLTFAAAGMVTTREFVCLAAWHLFSDAELLGHYRSADE FT TGRLAVLQELLRLEPVIGSLRRRATGPVELSCRDGPVTVRPGEYVEVHLDDANADPKAV FT GEEPLLVRPERAGAVGAGLSFGDGPHRCPGAHIALLETDVFLSRLFALDGVRMSGGPRV FT AFQEAIDGYEIRDLTVALPRAGRG" FT misc_feature complement(196450..196749) FT /note="Pfam match to entry PF00067 p450, Cytochrome P450, FT score 29.60, E-value 1.4e-07" FT misc_feature complement(196495..196524) FT /note="PS00086 Cytochrome P450 cysteine heme-iron ligand FT signature" FT repeat_region 197618..197710 FT /note="repeat region containing FT 3xATTCCGCCGAGTC(G/C)GGCGGTGCC repeat units" FT RBS 197780..197783 FT CDS 197792..198529 FT /transl_table=11 FT /gene="SCO7445" FT /gene_synonym="SC5C11.02" FT /product="hypothetical protein SC5C11.02." FT /note="SC5C11.02, unknown, len: 245 aa. Weakly similar to FT Escherichia coli SW:YJHP_ECOLI(EMBL:U14003) hypothetical FT 27.4 KD protein (248 aa), fasta scores opt: 301 z-score: FT 358.4 E(): 1.5e-12 28.2% identity in 248 aa overlap." FT /db_xref="HSSP:1NKV" FT /db_xref="InterPro:IPR013217" FT /db_xref="UniProtKB/TrEMBL:Q9L170" FT /protein_id="CAB76308.1" FT /translation="MDRQQISRLAHAHHPIAAPLDDDSVRRLLAQAVPGDGARVLDLGC FT GGAEWLLRALAGHPRLTAEGVDVSASALDHARGAAARLGVADRLTLHHEDAARFAAPHG FT FDLVLCVGSTHAFGGLPATLAAAREHLAPGGRVLVGDGFWEREPSPEAVESLGDLDDLP FT TTLDRVVADGWTPVGGHISTRRELDDYEWAWTGALAAWALDHPADPDRAQALETAIAHR FT DGWLRGYRDCLGFLCLVLRPTDT" FT CDS 198631..199071 FT /transl_table=11 FT /gene="SCO7446" FT /gene_synonym="SC5C11.03" FT /product="putative regulator." FT /note="SC5C11.03, possible regulator, len: 146 aa. Similar FT to Streptomyces fradiae TR:Q9Z9I5 (EMBL:AB024056) FT beta-lactamase regulator protein (139 aa), fasta scores FT opt: 215 z-score: 266.6 E(): 2e-07 36.6% identity in 131 FT aa overlap and Streptomyces coelicolor TR:Q9X7S3 FT (EMBL:AL049863) putative regulator protein, SC5H1.15C (151 FT aa), fasta scores opt: 347 z-score: 419.9 E(): 5.7e-16 FT 44.4% identity in 144 aa overlap." FT /db_xref="GOA:Q9L169" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9L169" FT /protein_id="CAB76309.1" FT /translation="MDGAARTGDRLKDGSVKVSAEYPGMPGDIARGRELARRFLARVRA FT AQGAQVSERTVEVVQLVVSELLTNACKYAPGPSLVDLELAEDRVEVTVWDSAPVLPVPG FT PADPTRVGRHGLEIVMAVCESFEVHREPVGKRMRAAVGLAAT" FT CDS complement(199520..200071) FT /transl_table=11 FT /gene="SCO7447" FT /gene_synonym="SC5C11.04c" FT /product="putative acetyltranferase." FT /note="SC5C11.04c possible acetyltranferase, len: 183 aa. FT Similar to many including: Proteus mirabilis FT TR:O86434(EMBL:AJ000084) putative acetyl transferase (185 FT aa), fasta scores opt: 428 z-score: 512.9 E(): 3.8e-21 FT 43.6% identity in 179 aa overlap. Contains a Pfam match to FT entry PF00583 Acetyltransf, Acetyltransferase (GNAT) FT family." FT /db_xref="GOA:Q9L168" FT /db_xref="HSSP:1NSL" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9L168" FT /protein_id="CAB76310.1" FT /translation="MSELRTDRLVLRGWRASDLDPWAAMNADPVVREYFPEVLTRAQSE FT ASVARFQADLDRRGWGWWAVEIAATGEFIGFAGLDPVEDGMPFTGVEAGWRLARPAWGN FT GFATEAARAAVTHAFEELGLPEVLAVTAAGNRRSRAVMDRLGMTYDPADDFDDPEIPEG FT PLRRSVVYRLRSRDHRPGAL" FT misc_feature complement(199628..200041) FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 41.20, E-value FT 2.4e-08" FT CDS 200207..202150 FT /transl_table=11 FT /gene="SCO7448" FT /gene_synonym="SC5C11.05" FT /product="hypothetical protein SC5C11.05." FT /note="SC5C11.05, unknown, len: 647 aa. Similar to another FT protein of undefined function from Streptomyces coelicolor FT TR:Q9X8W1(EMBL:AL078610) hypothetical 66.2 KD protein, FT SCH35.45c (634 aa), fasta scores opt: 1537 z-score: 1606.6 FT E(): 0 46.3% identity in 570 aa overlap. Contains a Pfam FT match to entry PF00989 PAS, PAS domain." FT /db_xref="GOA:Q9L167" FT /db_xref="InterPro:IPR010822" FT /db_xref="UniProtKB/TrEMBL:Q9L167" FT /protein_id="CAB76311.1" FT /translation="MRVVTSRWAGHQDGEEPGHDTAAEAHRAAAEAHGVPEDVEPDFSR FT AVLRALGTGVVTLGPTARITSVNPWAEHLLGRSEQEMLGRDAHDLLHRYADGSPVPRER FT CALRRPLHGAPAEEGSDEYFQRADGTTVPVIWATTPLVRGGRQEGLVLVFHDFSLHRSA FT AEETEARTTALEALTAQLHLVAEISTVLVPTERTSTTLRRLVRLLVPELGQWAAVDVYP FT GQSDLLERVAVRSSTRPDRARALRGPMASLPDQARAALTLLINGDRPVPLKADDLFRDP FT EHPLAATHRVLFERLGGHAAVAIPLRTRQRSYGVLTVGRAGDRPAHTEAEVALLADIGR FT RVGLVLDNARLYHEQRNVAETMQRQLLTPLPQVDHLRMAARYWPAESAMEVGGDWYDAF FT LLGDGVMALVIGDVVGHDLQAAAHMAEVRNMLRALAWDHQEPPSVIMRRLDEAVTNTSD FT APMATLVFARVEGAEGGPWRLHWVNAGHPPPLLITRDGGTRFLEGGHGPLIGMSATLRL FT GLNWPDTREELPPESILLLYTDGLVESRDRPIDVGMDQLRHHAGVLARRVDRWSVDDFC FT DELLARIAPRGDDVALLALRLPAAGMGAPGDTEPPPPPQSGQSEAAPDRAAPGSLRQEA FT EVRDPTHVDPED" FT RBS 202401..202405 FT CDS 202413..203090 FT /transl_table=11 FT /gene="SCO7449" FT /gene_synonym="SC5C11.06" FT /product="putative membrane protein." FT /note="SC5C11.06, possible secreted/membrane protein, len: FT 225 aa. Contains repeat sequences FT 3xGDW(N/D)HDD(S/T/A)S(Y/S)(S/G)KEHDNGSKHDEPRGG, FT 3xMHTGGG(A/G)LAV(T/N)E and 1xMHTGGGGLA. Also contains FT possible N-terminal region signal sequence peptide and FT possible membrane spanning hydrophobic domains." FT /db_xref="UniProtKB/TrEMBL:Q9L166" FT /protein_id="CAB76312.1" FT /translation="MRSARMLLTTAAASAVFVLGAPGAYAAAGGDWDHDDSSYSKEHDN FT GSKHDEPRGGMHTGGGALAAVTEGDWNHDDTSSGKEHDNGSKHDEPRGGMHTGGGALAA FT VNEGDWNHDDASSGKEHDNGSKHDEPRGGMHTGGGALAAVNEGDWDGGGRESKEGGSQT FT YQQDEGESSRGGGEHEKPRGGMHTGGGGLATPTTTAGGLAVLAVAATGLYAVRRKKSAH FT GVA" FT repeat_region 202500..202577 FT /note="imperfect direct repeat of bases 5133..5210 and FT 5250..5327" FT repeat_region 202578..202616 FT /note="imperfect direct repeat of bases 5211..5249 and FT 5328..5366." FT repeat_region 202617..202694 FT /note="imperfect direct repeat of bases 5016..5093 and FT 5250..5327" FT repeat_region 202695..202733 FT /note="imperfect direct repeat 0f bases 5094..5132 and FT 5328..5366." FT repeat_region 202734..202811 FT /note="imperfect direct repeat of bases 5016..5093 and FT 5133..5210." FT repeat_region 202812..202850 FT /note="imperfect direct repeat of bases 5094..5132 and FT 5211..5249." FT repeat_region 202965..202991 FT /note="incomplete direct repeat of bases 5094..5132, FT 5211..5249 and 5328..5366." FT CDS 203291..203896 FT /transl_table=11 FT /gene="SCO7450" FT /gene_synonym="SC5C11.07" FT /product="putative secreted protein" FT /note="SC5C11.07, possible secreted protein, len: 201 aa. FT Similar to Streptomyces coelicolor TR:CAB63184 FT (EMBL:AL133469) putative secreted protein, SCM10.23 (221 FT aa), fasta scores opt: 512 z-score: 527.4 E(): 5.9e-22 FT 41.4% identity in 198 aa overlap. Contains a possible FT N-terminal signal sequence." FT /db_xref="InterPro:IPR005754" FT /db_xref="UniProtKB/TrEMBL:Q9L165" FT /protein_id="CAB76313.1" FT /translation="MVLCAVALLILAVSLVGGNDTSADSSRPPLPAHPGTTASSAPPAT FT GAADSALPRSKPVRLLIPDIAVDAPFTDLAIGDKGQLQPPPAGDTNLVGWYAKGVSPGE FT KGTSIIAGHVDTKTSAAVFARLDQLDKGDKFQVRRADGRSATFVVDGLETFAKDEFPSD FT RVYGDADRPEVRLITCAGDYDHKVKDYTDNLVVFAHLA" FT CDS 204048..205244 FT /transl_table=11 FT /gene="SCO7451" FT /gene_synonym="SC5C11.08" FT /product="conserved hypothetical protein SC5C11.08" FT /note="SC5C11.08, unknown, len: 398 aa. Highly similar to FT several proteins of undefined function associated with FT polyketide biosynthesis including: Streptomyces coelicolor FT SW:WH42_STRCO(EMBL:X55942) 42.8 KD protein in whiE locus FT (WhiE ORF I) SC6G9.13 (397 aa), fasta scores opt: 1392 FT z-score: 1637.1 E():0 56.1% identity in 401 aa overlap and FT Streptomyces cyaneus (Streptomyces curacoi) FT SW:CURD_STRCN(EMBL:X62518) polyketide synthase, CurD (367 FT aa), fasta score opt: 1451 z-score: 1706.9 E():0 62.0% FT identity in 368 aa overlap." FT /db_xref="GOA:Q9L164" FT /db_xref="InterPro:IPR007575" FT /db_xref="UniProtKB/TrEMBL:Q9L164" FT /protein_id="CAB76314.1" FT /translation="MTTTSTPASGPLSSEALASGAIAPEPLTRQLSHQVSQSVFDGSRL FT RVVLLVEVYDGAQQQFLETYENLRSHVESVPGHLGEQLCQSIENPSQWLITSEWESAPP FT FLNWVSSEEHVRMVKPLHSCVRDTRSLRFHVVRETGHPSTGADPARGGLQAAPRVGDGV FT IRHALTFTVKPGSEEAVGKILADYASPEPQVDDTTRLCRTSLFLHGNRVVRAIEVRGDL FT LAALRHVAEQPEVRAVEEAINPYLEQDRDLGDPESARVFYTRAALPAVHHVTAGEGQDG FT AQRHALSYPARPGCGMRLAQLLAERDEAAARDPRSPVLCSTIFQRDDVVVRLVDVRGDL FT HEGDPAVTLGLPDPGRVSELTTLLDGFTDAGSPTGGGLVRALEGARMELVTDRRAPDA" FT CDS complement(205283..206311) FT /transl_table=11 FT /gene="SCO7452" FT /gene_synonym="SC5C11.09c" FT /product="putative O-methyltransferase." FT /note="SC5C11.09c, possible O-methyltransferase, len: 342 FT aa. Similar to many e.g. Streptomyces glaucescens FT SW:TCMN_STRGA (EMBL:M80674) multi-functional FT cyclase-dehydratase-3-O-methyl transferase, TcmN, forming FT the first step in the biosynthesis of the polyketide FT antibiotic tetracenomycin C (494 aa), fasta scores opt: 472 FT z-score: 554.8 E(): 1.8e-23 30.8% identity in 308 aa FT overlap and Streptomyces lavendulae FT TR:Q9X5T6(EMBL:AF127374) O-methyltransferase, MmcR, found FT within the mitomycin C biosynthetic cluster (351 aa), FT fasta scores opt: 654 z-score: 769.9 E(): 0 37.1% identity FT in 340 aa overlap. Contains a Pfam match to entry PF00891 FT Methyltransf_2, O-methyltransferase." FT /db_xref="GOA:Q9L163" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9L163" FT /protein_id="CAB76315.1" FT /translation="MTTAQTAPPPPMRLRELVFGAACAAALRAAARLGVADALGDTPMA FT VEDLAAAVKTEPKPLRRLLRALTCYGVFTEQRNGTFAHTDMSRLLREDDPHSLRNITLW FT CTEPWTWDAWPLLDEAVRTGSNVVEGLYGKEFFTYLNEDAPQSAEVFNRAMTTSSRQSA FT QDVAALLDLSASTSVADIGGGQGHVVASLLEKYPAMRGTLLDLPRVVENADPRLREGGA FT LADRVRIVPGDCREAIPVRADVYVIKNILEWDDDSTARALRNVMAAGGPGARVVVIENL FT VDDSPSMRFSTAMDLLLLLNVGGAKHTTDSMVGRLTDAGLVIDDIRPVNPYLHAFDCTV FT PK" FT misc_feature complement(205361..206080) FT /note="Pfam match to entry PF00891 Methyltransf_2, FT O-methyltransferase, score 136.80, E-value 3.8e-37" FT CDS complement(206376..207446) FT /transl_table=11 FT /gene="SCO7453" FT /gene_synonym="SC5C11.10c" FT /product="putative secreted protein" FT /note="SC5C11.10c, putative secreted protein, len: 356 aa. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="InterPro:IPR006626" FT /db_xref="UniProtKB/TrEMBL:Q9L162" FT /protein_id="CAB76316.1" FT /translation="MKKCHVVYLVCTAAMIGTGLGAAPASSVPRTHLVHPGESIQKAVD FT AAEPGDTVLVTTGTYRESVKVSTPRLTLRGMGRSTVIRPSTQKAAANTCAEGGNGICAI FT GTKDENVKGITVSDLTVTGFTRTGVFSMATDGLTVRNVNAVKNGVWGIAQERSVHGVFR FT GNTARDNGDAGIFLANNIKAEEGAADTEGTLVAHNRLEGNRIGVTVRRLRNLAVAGNHI FT TGNCAGVFVVGDENTPKAGDLVVRDNRVLRNNKSCPKTDRLEALQGSGIVLTGVEKVLV FT ADNTVEGNSGKSSMSGGIVLASSMVGTANAKNEVNGNRLSRNSPADLVNAGTGDTGRSN FT TFTGNTCGASKPAGLC" FT CDS 207590..208384 FT /transl_table=11 FT /gene="SCO7454" FT /gene_synonym="SC5C11.11" FT /product="putative membrane protein" FT /note="SC5C11.11, possible membrane protein, len: 264 aa. FT Contains possible membrane spanning hydrophobic domains." FT /db_xref="GOA:Q9L161" FT /db_xref="InterPro:IPR007560" FT /db_xref="UniProtKB/TrEMBL:Q9L161" FT /protein_id="CAB76317.1" FT /translation="MTVPERHVRGGRVRRRFDLRATTVTFGLAAVALVLTGWVVRMAFD FT VAQRRPAWVFVLVLGAVAAALLSRRARSRGAAARAALRTTDALAAATATALDELEQGRA FT VEEVEHACPEEATAVVRTEHEELSPDEFEEAIADLCRRDGCTEVEVVGGAGDLGADVLA FT TAPDGRRVVIQCKRYGDDNKVGSQDLQRFGGTCFTVHGADVAVLVTSSDFTAPAVEYAA FT WCGIVCVNEERLRDWCEGGGPAPWERLLPEGDGTEPPEQATW" FT CDS 208459..208995 FT /transl_table=11 FT /gene="SCO7455" FT /gene_synonym="SC5C11.12" FT /product="putative isochorismatase." FT /note="SC5C11.12, possible isochorismatase (EC 3.3.2.1), FT len: 178 aa. Similar to several including: Escherichia coli FT SW:ENTB_ECOLI(EMBL:M24148) isochorismatase (EC 3.3.2.1), FT EntB, involved in enterobactin biosynthesis (285 aa), fasta FT scores opt: 210 z-score: 266.3 E(): 2.1e-07 26.3% identity FT in 179 aa overlap. Contains a Pfam match to entry PF00857 FT Isochorismatase, Isochorismatase family." FT /db_xref="GOA:Q9L160" FT /db_xref="InterPro:IPR000868" FT /db_xref="UniProtKB/TrEMBL:Q9L160" FT /protein_id="CAB76318.1" FT /translation="MGKTALIVIDMINTYDHQDAESLIPAVESVLPNVTGLLDRARRQG FT VPVIYVNDNFGEWRSHHGEILDKALSGPHSRLVEPLKPDESSLFVVKARHSVFFETPLT FT YLLHQQGIDRLVLCGQVTEQCVLYSALDAHIRHLQVIVPRDAVAHIHADLADAALRMME FT RNMGARVCDSGELWT" FT misc_feature 208471..208932 FT /note="Pfam match to entry PF00857 Isochorismatase, FT Isochorismatase family, score 99.00, E-value 9.2e-26" FT CDS complement(209037..209528) FT /transl_table=11 FT /gene="SCO7456" FT /gene_synonym="SC5C11.13c" FT /product="hypothetical protein SC5C11.13c." FT /note="SC5C11.13c, unknown, len: 163 aa." FT /db_xref="UniProtKB/TrEMBL:Q9L159" FT /protein_id="CAB76319.1" FT /translation="MTSISADPRPLRTADLGTLVIMSWSRETPDGDVPFLLACSLGDGE FT GGPEAVPAAVEGLLSRSGLAVGGDTVLDATALPGLPIGLLVVPGAAALTMPGVNAQFVP FT TPEWRAAADRRGYACLIFATRPWPGGEPGDGEAVAAFANDADTLSSAAQVVLSVRSLRG FT " FT CDS complement(209571..209969) FT /transl_table=11 FT /gene="SCO7457" FT /gene_synonym="SC5C11.14c" FT /product="hypothetical protein SC5C11.14c." FT /note="SC5C11.14c, unknown, len: 132 aa." FT /db_xref="UniProtKB/TrEMBL:Q9L158" FT /protein_id="CAB76320.1" FT /translation="MDRLLVDEPVEPARDVEAPAEGPAEPDALVETMDTEVRETGGIAA FT RTGRAFHRVRAQVRGIGAAADGEEPARMHAGTVEAVRAGGAKAAEAAEAAVRRHFDDIR FT GRLSQHGRARAPVAPRSCEEGPGCPPVG" FT CDS 210128..210493 FT /transl_table=11 FT /gene="SCO7458" FT /gene_synonym="SC5C11.15" FT /product="putative membrane protein." FT /note="SC5C11.15, possible membrane protein, len: 121 aa. FT Similar in parts to several proteins of undefined function FT e.g. Mycobacterium tuberculosis TR:O53879(EMBL:AL022004) FT hypothetical 40.0 KD protein (407 aa), fasta scores opt: FT 331 z-score: 403.1 E(): 4.9e-15 50.0% identity in 108 aa FT overlap. Contains a possible membrane spanning hydrophobic FT domain." FT /db_xref="GOA:Q9L157" FT /db_xref="InterPro:IPR010618" FT /db_xref="UniProtKB/TrEMBL:Q9L157" FT /protein_id="CAB76321.1" FT /translation="MICRRNDRQSDVRGSRGRRIRTAAVTLVAATALGATGEAVAAPSA FT PLRTDWDAIAACESSGNWQANTGNGYYGGLQFARSSWIAAGGLKYAPRADLATRGEQIA FT VAERLARLQGMSAWGCA" FT CDS complement(210690..211529) FT /transl_table=11 FT /gene="SCO7459" FT /gene_synonym="SC5C11.16c" FT /product="putative ABC transport protein, ATP-binding FT component." FT /note="SC5C11.16c, possible ABC transporter protein, FT ATP-binding component, len: 279 aa. Highly similar to FT several transporters e.g. Escherichia coli FT SW:FEPC_ECOLI(EMBL:X57471) ferric enterobactin transport FT ATP-binding protein, FepC (271 aa), fasta scores opt: 408 FT z-score: 486.3 E(): 1.1e-19 35.2% identity in 244 aa FT overlap and Streptomyces coelicolor FT TR:Q9X9Z4(EMBL:AL079332) putative ABC transporter FT ATP-binding protein, SCI5.06c (265 aa), fasta scores opt: FT 666 z-score: 788.8 E():0 44.2% identity in 260 aa overlap. FT Contains Prosite hits to PS00017 ATP/GTP-binding site motif FT A (P-loop)and PS00211 ABC transporters family signature. FT Also contains a Pfam match to entry PF00005 ABC_tran, ABC FT transporter." FT /db_xref="GOA:Q9L156" FT /db_xref="HSSP:1L7V" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9L156" FT /protein_id="CAB76322.1" FT /translation="MTAQTARSQADEDEAAVLRLQDVSVRRFTPDQLILDGVNWTVRPG FT EHWALLGANGAGKTTLLRLLGALMHPTTGTVEVLGSRLGRVDVRELRARIGHVNSAQRV FT PQDLTAHAVVLTGHSGTVQPLWRTYGEEVRLRARDLLLELGVKELADRPYGVCSGGQRA FT RVLIARALMANPALLLLDEPFNALDLPSREDLVEAMHQLAERRPRLATVTVTHHLEELS FT PAVSHALLLREGRILSRGAVDEVLTGSLLTSCFGRDITVARRDGRWSAYSGRRVAGG" FT misc_feature complement(210828..211397) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 159.90, E-value 4.5e-44" FT misc_feature complement(211017..211061) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(211353..211376) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 211736..212806 FT /transl_table=11 FT /gene="SCO7460" FT /gene_synonym="SC5C11.17" FT /product="putative lipoprotein." FT /note="SC5C11.17, possible lipoprotein, len: 356 aa. FT Contains a possible N-terminal signal sequence and an FT appropriately positioned Prosite hit to PS00013 Prokaryotic FT membrane lipoprotein lipid attachment site." FT /db_xref="UniProtKB/TrEMBL:Q9L155" FT /protein_id="CAB76323.1" FT /translation="MGRRCTARGSGRRRAGRVGGGLAALLAGLLVTGCAAFDTDDDVRR FT ARELAAELYPGELEVVDARILFPETTGSEVTLSVEDDPDAAVRFRVDAGKDRCDGGPDC FT TDALREAVDRARREARDLRAMREAFDGCGHPVLAADEKLTAPWIEARVSDGTLDEVLAR FT AGACAQRWVTARAEQGPKEVPGWVTVNFAAPGTAEDLPAAKKRLPTVLRLTHGPRLAAL FT AGKAYYVAAYPVGEDAGHTVDAASARLRIVSPLEERQAFSRRIDASVLPALRATYPEAV FT TSGGAGMGVWRLEPGTVRRMRGYVLFCERPPADGERCPGDLAALVTSDPRGGDAEVVDV FT LTDIRDERGVLRLPPQ" FT misc_feature 211805..211837 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT stem_loop complement(212782..212825) FT /note="possible stem loop.Score 50: 18/19 (94%) matches, 0 FT gaps" FT CDS complement(212847..213533) FT /transl_table=11 FT /gene="SCO7461" FT /gene_synonym="SCBAC14E8.01c" FT /product="putative hydrolase" FT /note="SCBAC14E8.01c, probable hydrolase, len: 228 aa; FT similar to SW:TRYD_DROME (EMBL:U04853) Drosophila FT melanogaster trypsin delta precursor (EC 3.4.21.4) FT Try-delta, 253aa; fasta scores: opt: 220 Z-score: 237.9 FT bits: 51.4 E(): 1.1e-05; 32.271% identity in 251 aa FT overlap. Contains Pfam match to entry PF00089 trypsin, FT Trypsin" FT /db_xref="GOA:Q9ADJ8" FT /db_xref="HSSP:1FY4" FT /db_xref="InterPro:IPR001254" FT /db_xref="UniProtKB/TrEMBL:Q9ADJ8" FT /protein_id="CAC36053.1" FT /translation="MAALLSALALSPTASAVEPRPGDGGPQPIIGGGYAQNAPWAARLF FT SGGRQTCTSTIISPTWILTAKHCVSGGNLAFRIGSLDQGSGGTVANGVQTVTSPSADLA FT LVRLDRSVSATYARLGQPGTVRVGQSVQVYGWGATSRCGSEINCQSQYLKVANVSVTQG FT CYDAYYGQAICARPVDGITAGGDSGGPMMAGGVQVGVASTSDRQTTTAYTNVTAYRSWI FT QSVAGV" FT misc_feature complement(212868..213449) FT /note="Pfam match to entry PF00089 trypsin, Trypsin, score FT 93.60, E-value 6.9e-29" FT CDS complement(213745..214512) FT /transl_table=11 FT /gene="SCO7462" FT /gene_synonym="SCBAC14E8.02c" FT /product="putative integral membrane protein" FT /note="SCBAC14E8.02c, possible integral membrane protein, FT len: 255 aa; similar to TR:Q49657 (EMBL:U00011) FT Mycobacterium leprae hypothetical 27.1 kDa protein U1177B FT precursor MLCL581.28c, 260 aa; fasta scores: opt: 670 FT Z-score: 780.5 bits: 152.0 E(): 6.8e-36; 47.059% identity FT in 255 aa overlap. Contains possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q9ADJ7" FT /db_xref="InterPro:IPR002781" FT /db_xref="UniProtKB/TrEMBL:Q9ADJ7" FT /protein_id="CAC36054.1" FT /translation="MTPEAMAAVFAAGVGAGAINSVVGSGTLITFPVLLATGLPPVTAT FT VSNALGLIPGSISGAIGYRRELRGQRGRVLKFGSGALLGGLAGATLLLTLPADAFETVV FT PVLVGLALLLVAFQPQIGRLVQRRRARTGTSPRRDGGPLLLTGLTLASVYGGYFTAAQG FT IIYLSLMGMLLDEPLQRLNGVKNVLSAVVNTVAALFFLFAADFEWTAVGLLAVGSGLGG FT YVGAKVGRHFSPTVLRILVVTVGTVALVQLLLR" FT CDS 214830..216032 FT /transl_table=11 FT /gene="SCO7463" FT /gene_synonym="SCBAC14E8.03" FT /gene_synonym="cvnA13" FT /product="putative sensor histidine kinase" FT /note="SCBAC14E8.03, cvnA13, possible sensor histidine FT kinase, len: 400 aa; similar to TR:Q9L137 (EMBL:AL158061) FT Streptomyces coelicolor putative sensor histidine-kinase FT SC6D11.18c, 543 aa; fasta scores: pt: 500 Z-score: 444.9 FT bits: 91.6 E(): 3.3e-17; 32.591% identity in 359 aa overlap FT and to TR:Q9AJP4 (EMBL:AB044803) Streptomyces griseus ORF1, FT 543 aa; fasta scores: opt: 511 Z-score: 495.4 E(): FT 5.8e-20; 34.627% identity in 335 aa overlap. Contains Pfam FT match to entry PF02518 HATPase_c, Histidine kinase-, DNA FT gyrase B-, phytochrome-like ATPase and possible N-terminal FT region signal peptide sequence" FT /db_xref="GOA:Q9ADJ6" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9ADJ6" FT /protein_id="CAC36055.1" FT /translation="MTEYTGNPLLWVALVALVAAAVLISRQRKAARALRQQVQGLRDHY FT TELENDYGKSVQAAQERAEDETKTVLKSAMRTLQGLAAEQQLVLSRLQNKYGDSALLQD FT LLEIDHTNSQFGRRAQSIAVLCDGWLGGRRDTASVYDVVRSAQGRIRHFRRVDILSQAD FT FGITSRAVEPVALALAELLDNATSYSSPDTVVEINIRTVPKGICVVVDDAGVGMSDEER FT ARADKLLATERASGVAGLGNPPQFGFAVIGLLCERFGFEVSVDSSSPYGGVRAVVLLPH FT ELLTAMPEKKAPAPAPAAAPAARGTARPVPDGGPEAALTSSQTDGDGLPRRRRKRPMAI FT VPGSASNPRAAGRSDSEQAKVMGAFQRGTQSGRVTEPDSPDNAGRTSDTPGASSEGHEV FT S" FT misc_feature 215334..215501 FT /note="Pfam match to entry PF02518 HATPase_c, Histidine FT kinase-, DNA gyrase B-, phytochrome-like ATPase, score FT 19.00, E-value 0.00071" FT RBS 216021..216025 FT CDS 216029..216430 FT /transl_table=11 FT /gene="SCO7464" FT /gene_synonym="SCBAC14E8.04" FT /gene_synonym="cvnB13" FT /product="hypothetical protein" FT /note="SCBAC14E8.04, cvnB13, hypothetical protein, len: 133 FT aa; similar to TR:Q9L138 (EMBL:AL158061) Streptomyces FT coelicolor hypothetical 14.a kDa protein SC6D11.17c, 135 FT aa; fasta scores: opt: 321 Z-score: 425.0 bits: 84.4 E(): FT 4.3e-16; 40.476% identity in 126 aa overlap" FT /db_xref="InterPro:IPR004942" FT /db_xref="UniProtKB/TrEMBL:Q9ADJ5" FT /protein_id="CAC36056.1" FT /translation="MNDDLSWMLDSALEIPGALHAVLISADGLLMARTQDFDKDDADRV FT AAAMSGVQSLSRTLAFFCEDPSQTWRQTLVEFDGGWVFLISAGEGAYLGVSASPEVDMA FT DITFRMQQLVAQLGKRLTTPPRENLGARS" FT CDS 216427..216804 FT /transl_table=11 FT /gene="SCO7465" FT /gene_synonym="SCBAC14E8.05" FT /gene_synonym="cvnC13" FT /product="hypothetical protein" FT /note="SCBAC14E8.05, cvnC13, hypothetical protein, len: 125 FT aa; similar to TR:Q9X834 (EMBL:AL049727) Streptomyces FT coelicolor hypothetical 12.8 kDa protein SC9B1.14c, 119 aa; FT fasta scores: opt: 288 Z-score: 370.8 bits: 74.1 E(): FT 4.5e-13; 45.082% identity in 122 aa overlap. Contains a TTA FT leucine codon, possible target for bldA regulation" FT /db_xref="InterPro:IPR007995" FT /db_xref="UniProtKB/TrEMBL:Q9ADJ4" FT /protein_id="CAC36057.1" FT /translation="MTGHDGWQPEAPELVRPYVITKGRGLPDEDDLSLITLVTAAAGQP FT QRPARLSPEEQSLLDLCSAGYLSVAEIAGHTHFPLGVVRILLASLMEGGHLVTRPPVAR FT ARLADKEILEEVLNGLRAKFG" FT misc_feature 216466..216468 FT /gene="none" FT /note="TTA leucine codon. Possible target for bldA FT regulation" FT CDS 216842..217372 FT /transl_table=11 FT /gene="SCO7466" FT /gene_synonym="SCBAC14E8.06" FT /gene_synonym="cvnD13" FT /product="putative ATP/GTP-binding protein" FT /note="SCBAC14E8.06, cvnD13, possible ATP/GTP-binding FT protein, len: 176 aa; similar to TR:Q9XAE1 (EMBL:AL079356) FT Streptomyces coelicolor putative ATP/GTP-binding protein FT SC6G9.41c, 191 aa; fasta scores: opt: 615 Z-score: 755.2 FT bits: 146.4 E(): 1.7e-34; 55.172% identity in 174 aa FT overlap. Contains match to Prosite entry PS00017 FT ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9ADJ3" FT /db_xref="InterPro:IPR004130" FT /db_xref="UniProtKB/TrEMBL:Q9ADJ3" FT /protein_id="CAC36058.1" FT /translation="MKILVVGHFAVGKTTLIGSISEIEPLSTEETMTQAAESVDDLKGV FT QGKTTTTVAMDFGRLTISDRVVLYLFGTPGQQRFVQMWEDMARGALGALVLVDPERLAD FT SFPVIDLIEHYGLDYAIAVNHFDGAPLRDQRALREALDLLDDTPVVTCDARDEKSSAAA FT LTTLVRYLLDRTR" FT misc_feature 216860..216883 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 217625..217629 FT CDS 217637..218764 FT /transl_table=11 FT /gene="SCO7467" FT /gene_synonym="SCBAC14E8.07" FT /product="hypothetical protein" FT /note="SCBAC14E8.07, unknown, len: 375 aa" FT /db_xref="GOA:Q9ADJ2" FT /db_xref="InterPro:IPR017795" FT /db_xref="UniProtKB/TrEMBL:Q9ADJ2" FT /protein_id="CAC36059.1" FT /translation="MRAASTGADPQDASTLGSFTGGQLRRLGSVAGLSRADVETYAQVL FT TDALGPVAQRPLSLAPPTRTFLSDDHTPVEFSLSFRPGAAPAMRVLVEPGCGATSLADN FT GRAGLEAVRTMARRWHFTTDALDELLDLFLPPAPQGPLALWCALELRPGGVPGVKVYLN FT PAVGGEERSAATVREALRRLGHHQAFDSLPQGSGYPFLALDLGNWTEPRAKVYLRHDNL FT TAGRAARLSRTDSGLVPTAVEGFFRTAAGPGSDAGGLDGRPAQSCHSFTDPGAERPSGF FT TLYIPVRDYVRHDGEALARASTVLHHHGMDASVLHRALAALTERRPEDGVGLIAYLALA FT GQRDQPPRVTAYLSSEAYTVRPPVVETVRQPLSVG" FT CDS complement(218867..220165) FT /transl_table=11 FT /gene="SCO7468" FT /gene_synonym="SCBAC17A6.01c" FT /gene_synonym="SCBAC14E8.08c" FT /product="putative flavin-binding monooxygenase" FT /note="SCBAC17A6.01c, possible flavin-containing FT monooxygenase, len: >327aa: similar to many eg. TR:Q9S204 FT (EMBL:AL109747) putative flavin-containing monooxygenase FT SCJ21.03 from Streptomyces coelicolor (458 aa) fasta FT scores; opt: 909, Z-score: 1021.7, 45.399% identity FT (45.679% ungapped) in 326 aa overlap and SW:P31513 FT (FMO3_HUMAN) hepatic flavin-containing monooxygenase FMO3 FT (defects in which cause fish-odour syndrome) (531 aa) fasta FT scores; opt: 661, Z-score: 743.2, 34.024% identity FT (35.826% ungapped) in 338 aa overlap. Contains Pfam match FT to entry PF00743 FMO-like, Flavin-binding FT monooxygenase-like." FT /note="SCBAC14E8.08c, possible monooxigenase (fragment), FT len: >140 aa; similar to C-terminal region of SW:FMO5_RABIT FT (EMBL:L08449) Oryctolagus cuniculus dimethylaniline FT monooxygenase [N-oxide forming] 5 (EC 1.14.13.8) Fmo5, 532 FT aa; fasta scores: opt: 259 Z-score: 319.3 bits: 66.9 E(): FT 3.3e-10; 32.353% identity in 136 aa overlap" FT /db_xref="GOA:Q8CJJ9" FT /db_xref="InterPro:IPR000960" FT /db_xref="UniProtKB/TrEMBL:Q8CJJ9" FT /protein_id="CAD55403.1" FT /translation="MRVCVIGAGLSGLAMGHALKERGISFVCLEKAPDVGGIWRQPGAG FT ERGPGYQSLHLNTARQLTGYADFPMPSDYPLYPRHDQVAAYLRSFAEWAGLLDHVELRT FT EVLSVRQDSDGSWTVVSRDADGAQSARRFEQVVVASGHHTDPALPDPLPAGADSFAGTI FT LHSLDYRDGGDFAGRRVVVVGLGASAVDIAADLSRHAERTLLSVRRGLHIVPKQVFGMS FT LDEIAEAPWWNEMPFAERRRWVEQALLVARGRLSDYGLPEPDHPILSSATTLSDEILSR FT IRHGAVTPKPAIASFESDRVVFTDGSSEAADTVVYCTGFHMTFPFLPPGCPVAADGAVE FT LYRRIVPADRPGLYFVGLVRPAGALTRLVEAQAQWVARLVDGAAALPGTEEMREEISTY FT LAGIVERYGRTRGASIQVDVSPYLAEFREPLPV" FT misc_feature complement(219191..220162) FT /note="Pfam match to entry PF00743 FMO-like, Flavin-binding FT monooxygenase-like, score -144.60, E-value 1.2e-14" FT CDS complement(220277..221623) FT /transl_table=11 FT /gene="SCO7469" FT /gene_synonym="paaK" FT /gene_synonym="SCBAC17A6.02c" FT /product="phenylacetate-CoA ligase" FT /EC_number="6.2.1.30" FT /note="SCBAC17A6.02c, phenylacetate-CoA ligase, len: 448 FT aa: strongly similar to many e.g. TR:Q9L9C1 (EMBL:AF176259) FT aerobic phenylacetate-CoA ligase from Azoarcus evansii (440 FT aa) fasta scores; opt: 1896, Z-score: 2065.6, 63.825% FT identity (64.871% ungapped) in 434 aa overlap. Contains 2 FT Pfam matches to entry PF00501 AMP-binding, AMP-binding FT enzyme." FT /db_xref="GOA:Q93JC7" FT /db_xref="InterPro:IPR011880" FT /db_xref="UniProtKB/TrEMBL:Q93JC7" FT /protein_id="CAC44647.1" FT /translation="MSSEPTTGTAPAPRRGEPLPHDLLDDAERLSREQLRELQLDRLRA FT TLRHAYDNVELYRKKFDAAGVTPDDCRSLADLSRFPFTTKADLRDTYPFGMFAVPMADV FT RRVHASSGTTGRATVVGYTENDLSMWADVVARSIRAAGGRPGHKVHISYGYGLFTGGLG FT AHYGAERAGCTVIPASGGMTARQVQIIQDFRPEIIMVTPSYMLTLLDEFERQGVDPRTS FT SLQVGIFGAEPWTEEMRREIEERMDIHAVDIYGLSEVIGPGVAQECVETKDGLHIWEDH FT FYPEVVDPLTDAVLPGGEEGEIVFTSLTKEALPVIRYRTRDLTRLLPGTARPAFRRMRK FT VTGRCDDMIILRGVNVFPTQVEEIVLRTPGVAPHFQMRLTERGRMDHMTVRVEARPDAA FT PEQRDAAARAIAQGVKDGVGVTVEVEVVEPETLERSLGKIRRVWDQRGA" FT misc_feature complement(220508..220603) FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 21.30, E-value 5e-05" FT misc_feature complement(220712..221152) FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 42.90, E-value 4.2e-11" FT CDS complement(221620..222132) FT /transl_table=11 FT /gene="SCO7470" FT /gene_synonym="paaI" FT /gene_synonym="SCBAC17A6.03c" FT /product="putative phenylacetic acid degradation protein FT PaaI" FT /note="SCBAC17A6.03c, possible phenylacetic acid FT degradation protein PaaI, len: 170 aa: similar to many e.g. FT SW:P76084 (PAAI_ECOLI) phenylacetic acid degradation FT protein PaaI from Escherichia coli (140 aa) fasta scores; FT opt: 342, Z-score: 414.6, 45.902% identity (46.281% FT ungapped) in 122 aa overlap. Contains Pfam match to entry FT PF02584 DUF157, Uncharacterized protein PaaI." FT /db_xref="HSSP:1PSU" FT /db_xref="InterPro:IPR006683" FT /db_xref="UniProtKB/TrEMBL:Q93JC6" FT /protein_id="CAC44648.1" FT /translation="MVDTVSQATEQTPTEAMFSADEASRGLGIELVEHGEGTALVRMTV FT TPAMVNGHRIAHGGFLFLLADTAFACACNSHGPVTVAAGADIVFVAPAREGDVLVARAE FT ERVRYGRSGIYDVSVRRGDEVVAEFRGRSRSVRDDGRDRSARDDAGSRDARQDTARETP FT GTTKESR" FT misc_feature complement(221719..222084) FT /note="Pfam match to entry PF02584 DUF157, Uncharacterized FT protein PaaI, COG2050, score 102.20, E-value 1e-26" FT CDS 222297..223283 FT /transl_table=11 FT /gene="SCO7471" FT /gene_synonym="paaA" FT /gene_synonym="SCBAC17A6.04" FT /product="putative phenylacetic acid degradation protein FT PaaA" FT /note="SCBAC17A6.04, possible phenylacetic acid degradation FT protein PaaA, len: 328 aa: similar to many e.g. SW:P76077 FT (PAAA_ECOLI) phenylacetic acid degradation protein PaaA FT from Escherichia coli (309 aa) fasta scores; opt: 1540, FT Z-score: 1801.2, 69.967% identity (69.967% ungapped) in 303 FT aa overlap." FT /db_xref="GOA:Q93JC5" FT /db_xref="InterPro:IPR011881" FT /db_xref="UniProtKB/TrEMBL:Q93JC5" FT /protein_id="CAC44649.1" FT /translation="MTTTHAAEAPPPDAPDGLQEHFDATIARDQRIEPRDWMPDGYRKT FT LVRQIAQHAHSEIIGMQPEGEWITRAPSLRRKAILFAKVQDEAGHGLYLYSAAETLGAD FT RDDLTERLIEGRQKYSSIFNYPTLSFADVGVIGWFVDGAAICNQVPLCRSSYGPYARAM FT VRICKEESFHQRQGYELLMTMMRGTDAQREMVQDAVNRWWWPSLMMFGPPDDASPNSAR FT SMAWKIKRHSNDELRRRFVDMTVPQAEKLGVTLPDPELRWNEESGHHDFGTPDWDELMR FT VIKGDGPCNDRRMERRRTAHEEGAWVREAATAHAAKQAARAEKGAVA" FT CDS 223280..223591 FT /transl_table=11 FT /gene="SCO7472" FT /gene_synonym="paaB" FT /gene_synonym="SCBAC17A6.05" FT /product="putative phenylacetic acid degradation protein FT PaaB" FT /note="SCBAC17A6.05, possible phenylacetic acid degradation FT protein PaaB, len: 103 aa: similar to many e.g. SW:P76078 FT (PAAB_ECOLI) phenylacetic acid degradation protein PaaB FT from Escherichia coli (95 aa) fasta scores; opt: 427, FT Z-score: 565.4, 66.667% identity (66.667% ungapped) in 90 FT aa overlap." FT /db_xref="InterPro:IPR009359" FT /db_xref="UniProtKB/TrEMBL:Q93JC4" FT /protein_id="CAC44650.1" FT /translation="MTPETARKPDGRGWPLYEVFVRGKRGLNHVHVGSLHAADDAMALT FT HARDLYTRRNEGVSIWVVRSEHIAASTRDEKDPFFAPSADKVYRHPTFYDIPDDVPHI" FT CDS 223601..224428 FT /transl_table=11 FT /gene="SCO7473" FT /gene_synonym="paaC" FT /gene_synonym="SCBAC17A6.06" FT /product="putative phenylacetic acid degradation protein FT PaaC" FT /note="SCBAC17A6.06, possible phenylacetic acid degradation FT protein PaaC, len: 275 aa: similar to many e.g. SW:P76079 FT (PAAC_ECOLI) phenylacetic acid degradation protein PaaC FT from Escherichia coli (248 aa) fasta scores; opt: 470, FT Z-score: 547.8, 41.057% identity (44.105% ungapped) in 246 FT aa overlap." FT /db_xref="GOA:Q93JC3" FT /db_xref="HSSP:1OTK" FT /db_xref="InterPro:IPR011882" FT /db_xref="UniProtKB/TrEMBL:Q93JC3" FT /protein_id="CAC44651.1" FT /translation="MSDDHVYLTLAEGHEDDTRWAYGTGFEDPLHGVDTTVPEGVDATA FT LAAECVALADDALVSAQRLAEWVTRAPELEEEVALANIGLDLLGQARLLYSRAGQADGT FT GRGEDAYAYFRDAGDFRNVRLTELPGGDFAFAVVRLLVLSSWRLAHFRRLETHPDPVLA FT AVAAKGVKELTYHRQYAAEWCVRLGDGTDESHRRMRAALDEVAPYLGELHTAYDVRDEV FT ADDLRQVTEAAGLPLPVYRPLPGSGRAGEHTEHLAPLLTELQGIARAHPEATW" FT CDS 224425..224937 FT /transl_table=11 FT /gene="SCO7474" FT /gene_synonym="paaD" FT /gene_synonym="SCBAC17A6.07" FT /product="putative phenylacetic acid degradation protein FT PaaD" FT /note="SCBAC17A6.07, possible phenylacetic acid degradation FT protein PaaD, len: 170 aa: similar to many e.g. SW:P76080 FT (PAAD_ECOLI) phenylacetic acid degradation protein PaaD FT from Escherichia coli (167 aa) fasta scores; opt: 474, FT Z-score: 518.6, 45.395% identity (47.586% ungapped) in 152 FT aa overlap. Contains Pfam match to entry PF01883 DUF59, FT Domain of unknown function DUF59." FT /db_xref="InterPro:IPR011883" FT /db_xref="UniProtKB/TrEMBL:Q93JC2" FT /protein_id="CAC44652.1" FT /translation="MTRDPALADARRARHVAEQVPDPELPMLTLADLGVLRDVEVDGDG FT TVVASLTPTYSGCPAMAEMRADVAARLRAAGYPRVEIRTVLDPPWTSDWITESGRGKLA FT EHGIAPPGAAPRGPVSLVLSPTRPAVPCPRCGSADTEETSRFAATSCKALWRCRACREP FT FEYVKEI" FT misc_feature 224449..224676 FT /note="Pfam match to entry PF01883 DUF59, Domain of unknown FT function DUF59, score 58.60, E-value 1.3e-13" FT CDS 224937..226043 FT /transl_table=11 FT /gene="SCO7475" FT /gene_synonym="SCBAC17A6.08" FT /product="putative phenylacetic acid degradation NADH FT oxidoreductase PaaE" FT /note="SCBAC17A6.08, possible phenylacetic acid degradation FT NADH oxidoreductase PaaE, len: 368 aa; similar to many e.g. FT SW:P76081 (PAAE_ECOLI) probable phenylacetic acid FT degradation NADH oxidoreductase PaaE from Escherichia coli FT (356 aa) fasta scores; opt: 871, Z-score: 943.6, 39.943% FT identity (40.870% ungapped) in 353 aa overlap. Contains FT Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur FT cluster binding domains; Pfam match to entry PF00175 FT NAD_binding, Oxidoreductase FAD/NAD-binding domain; Pfam FT match to entry PF00970 FAD_binding_6, Oxidoreductase FT FAD-binding domain and Prosite match to PS00197 2Fe-2S FT ferredoxins, iron-sulfur binding region signature." FT /db_xref="GOA:Q93JC1" FT /db_xref="HSSP:2CJO" FT /db_xref="InterPro:IPR017927" FT /db_xref="UniProtKB/TrEMBL:Q93JC1" FT /protein_id="CAC44653.1" FT /translation="MAPTAPVPAAPVRTRRRPAFHRLRVAAVERLCADAAAVSFEIPDE FT LAGEFVFAPGQSLTLRREVDGRDERRSYSICAPAGSAPRIGVRVVPGGLFSAWLVDEVR FT PGDTVEVMAPTGLFTPDLSTPGHHVLVAAGSGITPMVSIAESVLAADDRSTVTLFYGNR FT RTDTVMFADELADLKDLHPTRFHLAHVLSREPREAEVLSGRLDAGRLAALVGSLVDVER FT ADHWWLCGPQGMVADAQQVLTGLGVPAGRVHRELFYADDEPVREVRHEESGPEGPVSEV FT TITLDGRSTTSSLSRERSVLDGAQQTRPDLPFACKGGVCGTCRALVTDGSVDMRRNYAL FT ETAEVDAGYVLTCQSYPVSEKLTVDYDS" FT misc_feature 225000..225293 FT /note="Pfam match to entry PF00970 FAD_binding_6, FT Oxidoreductase FAD-binding domain, score 74.00, E-value FT 3.1e-18" FT misc_feature 225309..225659 FT /note="Pfam match to entry PF00175 NAD_binding, FT Oxidoreductase FAD/NAD-binding domain, score 64.90, E-value FT 1.7e-15" FT misc_feature 225777..226013 FT /note="Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur FT cluster binding domains, score 48.10, E-value 2e-10" FT misc_feature 225879..225905 FT /note="PS00197 2Fe-2S ferredoxins, iron-sulfur binding FT region signature" FT stem_loop 226066..226254 FT /note="Score 55: 25/27 ( 92%) matches, 1 gaps. Possible FT transcriptional terminator." FT CDS complement(226251..227468) FT /transl_table=11 FT /gene="SCO7476" FT /gene_synonym="SCBAC17A6.09c" FT /product="putative secreted protein" FT /note="SCBAC17A6.09c, possible secreted protein, len: FT 405aa: no significant database matches. Contains a possible FT N-terminal signal sequence." FT /db_xref="UniProtKB/TrEMBL:Q93JC0" FT /protein_id="CAC44654.1" FT /translation="MSSAPPRRHRRSRAVLLATLTAALTGTLLTGPGSAISRADAAPAA FT FTHPGVTVSQGQLDFARAKVDAGAQPWKGAFDQMMASRYADLNRAPKPRAVVECGSYSN FT PDYGCTDEREDAIAAYTNALAWYFTRDERYARKSIELMDAWSAVLRDHTNSNAPLQTGW FT AGSSWPKAAEIIKYTYGGAWANSGRFATMLRDVYLPEIINGSNSNGNWELTMTEAAVGI FT SVFLEDRASYDKAVARFRTRTAAYVYLNSDGELPKTVPSQHLDTRDKIVKYWQGQSTFV FT TGLTQETCRDFTHTGYGISSISHIAETSRIQGQDLYGTDVGERLRHALGFQAKYQQGAA FT VPSWLCGGKADLGLGPVTEVGYNALHNRLGFAMTNTQALTERTRPSGTNNLFVAWETLT FT HGDNPA" FT CDS 227725..229218 FT /transl_table=11 FT /gene="SCO7477" FT /gene_synonym="SCBAC17A6.10" FT /product="putative membrane protein" FT /note="SCBAC17A6.10, possible membrane protein, len: 497 FT aa: no significant database matches. Contains a possible FT hydrophobic membrane spanning region and Prosite match to FT PS00216 Sugar transport proteins signature 1." FT /db_xref="InterPro:IPR005829" FT /db_xref="UniProtKB/TrEMBL:Q93JB9" FT /protein_id="CAC44655.1" FT /translation="MTTPPAPAHDTRPTHRRSRPAVVAAALAAVFLGTLGNVSAAPARA FT AGEPPAGQSAAGQPSVADCPPALAGKATCYTGRDAGGAYYTMAVPHRWNGSLVVHAHGG FT PDLGDASDPARSTEDLERWAVMVDQGYAWAASSYRRGGYGARMAAADTENVRRLFTDRF FT GRPEHTYLHGQSWGGNVAAKAAEIYGRRPGAYDGVLLTNGVLGGGSRGYDYRVDLRVVY FT QYYCHNHPRPSEPQYPLWQGLRPGSTMTTAGLRARLQECTGYASEPADRTRAQQRNLDD FT ILAVTGIPERTLESHLRFATFTFRDIVTNRLGGRNPWSNRGVRYSGSHDDKALNAGVER FT FSADPTARRDLSYDSDLTGRVSLPVLTLHAIDDPTAFVEHEAAYRATLRGAGRDQDLVQ FT TFTREHEHSSLSDSEYAASISALDSWVRTGRRPNPRAIAASCAAFDARYAEGCFYDPGF FT HPAPYAARVRPRPGGLSWPAMTAAQERAWSRIEGVGIAP" FT misc_feature 228265..228315 FT /note="PS00216 Sugar transport proteins signature 1" FT CDS complement(229215..230117) FT /transl_table=11 FT /gene="SCO7478" FT /gene_synonym="SCBAC17A6.11c" FT /product="putative phosphotransferase" FT /note="SCBAC17A6.11c, possible phosphotransferase, len: FT 300aa: similar to many some of which are antibiotic FT resistance determinants eg. TR:O05841 (EMBL:Z95120) FT hypothetical protein from Mycobacterium tuberculosis (474 FT aa) fasta scores; opt: 971, Z-score: 1047.4, 49.315% FT identity (50.000% ungapped) in 292 aa overlap and TR:Q53826 FT (EMBL:U13078) capreomycin phosphotransferase from FT Streptomyces capreolus (281 aa) fasta scores; opt: 162, FT Z-score: 183.1, 28.632% identity (30.734% ungapped) in 234 FT aa overlap. Contains Pfam match to entry PF01636 APH, FT Aminoglycoside phosphotransferase." FT /db_xref="GOA:Q93JB8" FT /db_xref="InterPro:IPR002575" FT /db_xref="UniProtKB/TrEMBL:Q93JB8" FT /protein_id="CAC44656.1" FT /translation="MSSGQTHPDRCRVDDRLVRSLVDGQFPRWSGLPLERFPSGGTVNA FT MYRLGEDMVVRLPLIEGGAADVATERAWLPRLSPLLPTPVPEVLGEGAPGDGYPWPWSV FT YRWLPGEHPEAGALTDPVRLAEDLAAFVAAMRGISPSDAPKAYRGGPLTTLDAPTRAAL FT DELRALPEEDVDCDALAAVWRDALRAPAWEGPPGWLHADLMPGNLLVSGGRLSAVIDFG FT CMGVGDPACDLFPAWNLLPSGAREVFREALGVDDATWRRGRGRTLSQALIALPYYRKTN FT PAMAGNARHVIRAVLGMSG" FT misc_feature complement(229344..230084) FT /note="Pfam match to entry PF01636 APH, Aminoglycoside FT phosphotransferase, score -81.40, E-value 0.0019" FT CDS complement(230151..231314) FT /transl_table=11 FT /gene="SCO7479" FT /gene_synonym="SCBAC17A6.12c" FT /product="putative integral membrane protein" FT /note="SCBAC17A6.12c, possible integral membrane protein, FT len: 387aa: similar to many eg. TR:Q9FAT6 (EMBL:AB038042) FT Mrx hypothetical protein associated with macrolide FT 2'-phosphotransferase I in Escherichia coli plasmid pTZ3509 FT (412 aa) fasta scores; opt: 316, Z-score: 317.3, 29.873% FT identity (31.978% ungapped) in 395 aa overlap. Contains FT multiple possible membrane-spanning hydrophobic regions." FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q93JB7" FT /protein_id="CAC44657.1" FT /translation="MPKGYSLRSYLTAATAARAGDEMSGPALLLAGLAVTGSTTDSSTL FT LAGITVSAAVGGPVLGALLDRAGRPGRLLAGALALYATGLMVILAGLGRIPMACTLPLA FT VLTGLLGPALSGGWTAQLPRVAADARLSRANALDAMTFDVASLAGPALAGGVAELLGAS FT TALALAAALITAAVPAAWRLPAGPVRDRGTRSAPVAGALAAGFRVVLRRPLLARATLTS FT VASCAAQGMLAACVPLIGAQWLGTAGRGVLLFSGAAVSALAANAVLARRPLTVAPDTVV FT RAGALVQAGALLLAATGRPVALVAAVLVLGIGEGPQLTALFAVRHRETPEHLRGQVFTT FT GASLKITAFALGVAVAGPLAAWSLPGTLALAAGTAAGGALALGRESV" FT CDS 231353..231976 FT /transl_table=11 FT /gene="SCO7480" FT /gene_synonym="SCBAC17A6.13" FT /product="conserved hypothetical protein" FT /note="SCBAC17A6.13, conserved hypothetical protein, len: FT 207aa: similar to many from streptomycetes eg. TR:Q9L267 FT (EMBL:AL137778) hypothetical protein SCL2.32 from FT Streptomyces coelicolor (186 aa) fasta scores; opt: 221, FT Z-score: 262.6, 31.928% identity (32.515% ungapped) in 166 FT aa overlap." FT /db_xref="InterPro:IPR010852" FT /db_xref="UniProtKB/TrEMBL:Q93JB6" FT /protein_id="CAC44658.1" FT /translation="MRYIRLVPLSHGVDADADVHDPDWSTRHSVLATARRTAALVNVLA FT AGPSDAGGGPVPGAVAEVLRAYGEKEPLDLTARDVEGMREAATLLRDVFAAESADAAAH FT VLNRLLGAHTGRVRLTSHGGGTPWHPHLDRDDEAPWPEWFLASSCLALTVLVWDHQRPP FT GRICASGSCRDVFITRGSGPERRYCSRRCATRERVAAHRRRADG" FT CDS complement(231977..232552) FT /transl_table=11 FT /gene="SCO7481" FT /gene_synonym="SCBAC17A6.14c" FT /product="conserved hypothetical protein" FT /note="SCBAC17A6.14c, conserved hypothetical protein, len: FT 191aa: similar to many eg. TR:Q9F2L4 (EMBL:AL442629) FT hypothetical protein from Streptomyces coelicolor (151 aa) FT fasta scores; opt: 588, Z-score: 595.0, 65.185% identity FT (65.185% ungapped) in 135 aa overlap and TR:Q52355 FT (EMBL:U59239) TerB tellurite resistance protein from FT Serratia marcescens plasmid R478 (151 aa) fasta scores; FT opt: 240, Z-score: 254.3, 28.467% identity (28.467% FT ungapped) in 137 aa overlap" FT /db_xref="InterPro:IPR002097" FT /db_xref="UniProtKB/TrEMBL:Q93JB5" FT /protein_id="CAC44659.1" FT /translation="MAMWDKIKDQAKTFQQSQGTRGASGSGQGSHGPAGGGRPGSSSGG FT SKAQLIGMFKSQLASAKNELKSGAYRDASMAMCALVAAADGRVEPAERQRVEELIVSNE FT VLQNFPADQLRQRFNQHVDRLLANFEQGKAEALQVIAKAAKKPAEARAVVQTGMVVAGA FT DGSFEPSEQYAIREACTALNIPPSEFGV" FT CDS 232744..233145 FT /transl_table=11 FT /gene="SCO7482" FT /gene_synonym="SCBAC17A6.15" FT /product="putative integral membrane protein" FT /note="SCBAC17A6.15, possible integral membrane protein, FT len: 133aa: appears to have a motif in common with others FT eg. TR:Q9L4T7 (EMBL:AF265258) dolichyl-phosphate FT beta-glucosyltransferase from Rhodococcus sp. S9 (449 aa) FT fasta scores; opt: 215, Z-score: 268.3, 40.310% identity FT (41.935% ungapped) in 129 aa overlap. Contains possible FT membrane-spanning hydrophobic regions." FT /db_xref="GOA:Q93JB4" FT /db_xref="InterPro:IPR007267" FT /db_xref="UniProtKB/TrEMBL:Q93JB4" FT /protein_id="CAC44660.1" FT /translation="MWSREVGWFVAIGVASTAGQALLYWGLRPWSPPAVANLVSLLVLT FT VLNTEANRRLTFRHAATTPARAHLGAGGLFLLGYLVTSGAVLWFTHLRPDASPAAETAV FT LATASVAVTVVRFVVLRLAVFRTARQDTT" FT CDS 233316..233723 FT /transl_table=11 FT /gene="SCO7483" FT /gene_synonym="SCBAC17A6.16" FT /product="conserved hypothetical protein" FT /note="SCBAC17A6.16, conserved hypothetical protein, len: FT 135aa: similar to many eg. TR:BAB48518 (EMBL:AP002996) FT hypothetical protein MLL1058 from Rhizobium loti (148 aa) FT fasta scores; opt: 285, Z-score: 348.9, 39.850% identity FT (41.732% ungapped) in 133 aa overlap. Contains Pfam match FT to entry PF01042 UPF0076, YjgF family." FT /db_xref="HSSP:1JD1" FT /db_xref="InterPro:IPR006175" FT /db_xref="UniProtKB/TrEMBL:Q93JB3" FT /protein_id="CAC44661.1" FT /translation="MAITLVNPGGLPEIDVYRQVSIASGSKLVFVAGQVAWDADGVTVG FT EGDLAAQTEQCYLNVATALAAAGASFADVAKLNVHVADWTPDKMPLLLAGIERAAAKLG FT VTPAAPATLLGVAALDVPEHLVEVEATAVLG" FT misc_feature 233337..233717 FT /note="Pfam match to entry PF01042 UPF0076, YjgF family, FT score 65.60, E-value 1e-15" FT CDS complement(233730..233966) FT /transl_table=11 FT /gene="SCO7484" FT /gene_synonym="SCBAC17A6.17c" FT /product="hypothetical protein" FT /note="SCBAC17A6.17c, unknown, len: 78 aa: no significant FT database matches." FT /db_xref="UniProtKB/TrEMBL:Q93JB2" FT /protein_id="CAC44662.1" FT /translation="MSQASLSGSVAVPRALTRVELFGAGRPLVYDTAGLDHEECWPVLR FT RDFATAVRSGKPTQVDAGRGLYLQSLLDRVVHG" FT CDS complement(233963..234649) FT /transl_table=11 FT /gene="SCO7485" FT /gene_synonym="SCBAC17A6.18c" FT /product="putative oxidoreductase" FT /note="SCBAC17A6.18c, possible oxidoreductase, len: 228aa; FT similar to many eg. TR:Q9L2J5 (EMBL:AL137165) putative FT oxidoreductase SCF42.24 from Streptomyces coelicolor (295 FT aa) fasta scores; opt: 450, Z-score: 508.6, 43.850% FT identity (45.304% ungapped) in 187 aa overlap and FT TR:BAB49857 (EMBL:AP003000) probable oxidoreductase from FT Rhizobium loti (319 aa) fasta scores; opt: 243, Z-score: FT 278.7, 31.980% identity (35.795% ungapped) in 197 aa FT overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, FT Oxidoreductase family, NAD-binding Rossmann fold." FT /db_xref="GOA:Q93JB1" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q93JB1" FT /protein_id="CAC44663.1" FT /translation="MTASPHDRLPPFPADRRETFADRNAVTADPAPWTDRPVEVGLVGA FT GPWARAMHARVLAAGPETRLAAVWARRTEAARETAAPYGAHVAADFEELLDHCEAVAFA FT VPPAVQAELAPLAAKRGKDLLLEKPLGPDLAAARRVADAVAESGVVSQLVLTKRYHPAT FT RAFLEAARSFEAVGARSCYLHGAFLGGDFATGWRLEHGALLDLGPHLLDLLDAAVGPPA FT STRTVP" FT misc_feature complement(234185..234538) FT /note="Pfam match to entry PF01408 GFO_IDH_MocA, FT Oxidoreductase family, NAD-binding Rossmann fold, score FT 69.40, E-value 7.6e-17" FT CDS complement(234646..235863) FT /transl_table=11 FT /gene="SCO7486" FT /gene_synonym="SCBAC17A6.19c" FT /product="putative ROK-family transcriptional regulator" FT /note="SCBAC17A6.19c, possible ROK-family transcriptional FT regulator, len: 405 aa; similar to many e.g. TR:P95610 FT (EMBL:X99622) putative regulator from Rhodococcus FT erythropolis (397 aa) fasta scores: opt: 548, Z-score: FT 588.4, 36.776% identity (38.220% ungapped) in 397 aa FT overlap. Contains Pfam match to entry PF00480 ROK, ROK FT family and Prosite match to PS01125 ROK family signature." FT /db_xref="InterPro:IPR000600" FT /db_xref="UniProtKB/TrEMBL:Q93JB0" FT /protein_id="CAC44664.1" FT /translation="MGDTMMTSSQASAGELLHLIRSGRANTRADLQQATGLSRSTVGQR FT LDLLNRAGWLRHSTGTSTGGRPSHRIAFDPGHASVIAFDLETRHARAAVLDLAGTILAE FT HTGPMDVGAGPDRVLEGLADWFPDLIAAAGVPASHVAGIGLSVPGPVDWESGQVIEPPI FT MPGWDRYPIRERLQEAYASRLGLDPAAAEAVPVLVDNDANLMALAEHQANHRDCASFVL FT LKVSTGIGAGVVIGDRLYRGIDGGAGDIGHIRLHDRSDALCMCGSHGCLAAVASGRAIA FT GELAALGHDTASGRDVRRLLNEGHPDAVRLAREAGRRVGEVLVTVVTLLNPGVLMIAGE FT LAGVPFLTGVRELVYQRAMPRATANLQVVTSRLGDHAGLVGAAAMVVEHLYSPAGADAR FT LERLAS" FT misc_feature complement(235024..235620) FT /note="Pfam match to entry PF00480 ROK, ROK family, score FT 122.50, E-value 2.4e-35" FT misc_feature complement(235108..235191) FT /note="PS01125 ROK family signature" FT CDS complement(235867..236751) FT /transl_table=11 FT /gene="SCO7487" FT /gene_synonym="SCBAC17A6.20c" FT /product="putative integral membrane binding protein FT dependent transport protein" FT /note="SCBAC17A6.20c, possible integral membrane binding FT protein dependent transport protein, len: 294aa; similar to FT many eg. TR:BAB49483 (EMBL:AP002999) permease protein of FT sugar ABC transporter from Rhizobium loti (296 aa) fasta FT scores: opt: 608, Z-score: 696.1, 35.570% identity FT (36.934% ungapped) in 298 aa overlap. Contains Pfam match FT to entry PF00528 BPD_transp, Binding-protein-dependent FT transport systems inner membrane component, Prosite match FT to PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign. and multiple hydrophobic possible FT membrane spanning regions." FT /db_xref="GOA:Q93JA9" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q93JA9" FT /protein_id="CAC44665.1" FT /translation="MSGKTALSRARFEERFFGVARWIVIAFLAVITLLPFYYMVLLSLK FT PIDALLLDPGSLWISAKDFTLSTYRDVLRSTDDGGQGFLRFLLNSALVSLGTVVLTLVA FT AVPGAYAVSRLKFFGHRQVSALFLAVYLFPATLLAVPLFVIFAKIGLSSSLVGLAVVYV FT AQTVPVSIYMLKNYLVTIPASIEEAAALDGCSRLQTVRKVILPLALPSLMATGLYVFMI FT AWNEFLFALLFLAADPGQWTVSLGLAQLSNGIEVPKTVLMAGSVVLTIPVVLLFFAAER FT LLTEGLTSGADKS" FT misc_feature complement(235996..236223) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 73.50, E-value 4.4e-18" FT misc_feature complement(236134..236220) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS complement(236748..237779) FT /transl_table=11 FT /gene="SCO7488" FT /gene_synonym="SCBAC17A6.21c" FT /product="putative integral membrane binding protein FT dependent transport protein" FT /note="SCBAC17A6.21c, possible integral membrane binding FT protein dependent transport protein, len: 343aa; similar to FT many eg. SW:Q04698 (MALC_STRPN) maltodextrin transport FT permease from Streptococcus pneumoniae (435 aa) fasta FT scores: opt: 376, Z-score: 423.7, 26.959% identity FT (29.153% ungapped) in 319 aa overlap. Contains Pfam match FT to entry PF00528 BPD_transp, Binding-protein-dependent FT transport systems inner membrane component, Prosite match FT to S00402 Binding-protein-dependent transport systems inner FT membrane comp sign. and multiple hydrophobic possible FT membrane spanning regions." FT /db_xref="GOA:Q93JA8" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q93JA8" FT /protein_id="CAC44666.1" FT /translation="MPTAPAGAPQRRDTSRRSTDPSGDRSPAPDRRPLTASRRANRAGL FT AFVSPTFLVVLVVVVLPIAWTVLLAFQKARLVDIQGMGLFGNWSLDNFSQVFDSAGFWS FT SLGTTLLYTAGATLGSVVLGLVAALALRKPFRGRGLLRAAMLLPYVAPVVAVAFVWEVA FT LSPQYGVVNDWGRRLFGWDDPIAFLSTRQYEVDLLGLHFDIPLALLTVIVFECWRYFPF FT AFLFILARLQAVPDTLEEAALVDGATPTQRFRHVLLPQLMPVIALLCVLRFIMTFNKFD FT DVYLLTGGGAGTDVAAVRVYDFLTARYDVGAAAAQALVLALSLMILLGFYFKFFGNKVQ FT EEA" FT misc_feature complement(236865..237092) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 63.00, E-value 6.3e-15" FT misc_feature complement(237003..237089) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS complement(237813..239216) FT /transl_table=11 FT /gene="SCO7489" FT /gene_synonym="SCBAC17A6.22c" FT /product="putative binding protein dependent transport FT lipoprotein" FT /note="SCBAC17A6.22c, possible binding protein dependent FT transport lipoprotein, len: 467aa; weakly similar to many FT eg. SW:P76042 (YCJN_ECOLI) putative ABC transporter from FT Escherichia coli (430 aa) fasta scores: opt: 346, Z-score: FT 385.6, 26.009% identity (29.668% ungapped) in 446 aa FT overlap. Contains Pfam match to entry PF01547 FT SBP_bacterial_1, Bacterial extracellular solute-binding FT protein and Prosite match to PS00013 Prokaryotic membrane FT lipoprotein lipid attachment site" FT /db_xref="GOA:Q93JA7" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:Q93JA7" FT /protein_id="CAC44667.1" FT /translation="MRIRTLRSRTIAVGVTAALGIGLLSGCASSTGPGRPDREITVWSQ FT ENLPDRVAATQKVIDGFEKKTGVKVKLVGVDEKQMPQLIMSAAASGTLPDVIGAAPMGQ FT VWQMYSNGLLNTDIPKRIVDGLGRDTFNANALELTSDGGTSLGVPSDAWLQLLVYRKDQ FT FGQRSLPAPTTYAKALAAAKALTTEGHDGISAATDPSDAFTSQSFESLALANDCQLVDD FT RHEVALDSPRCQEAFRTYDRLARTYGAPGTQTVDSTRATYFAGRSSMVIWSSFLLDELA FT GLRKDALPSCPQCAKDPRYLSDHSGIVTAMQGPDADEAAQFGEITSWVTTKTAETAASR FT EFIEYMMGTGYESWFGMAPEGKIPVRKGTAAEPERYLDAWRHSDIGVDTRKPLDEVFPT FT SLLDQLADGVSNMRRWGITQGEGALVGATNGELPVPKAIGAMTSGQSSPSEAARDADEE FT VAALRKSLQ" FT misc_feature complement(237858..239078) FT /note="Pfam match to entry PF01547 SBP_bacterial_1, FT Bacterial extracellular solute-binding protein, score FT 74.60, E-value 2e-18" FT misc_feature complement(239136..239168) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature 239342..239455 FT /note="High content of proline, valine and serine amino FT acid residues" FT CDS 239342..240487 FT /transl_table=11 FT /gene="SCO7490" FT /gene_synonym="SCBAC17A6.23" FT /product="putative oxidoreductase" FT /note="SCBAC17A6.23, possib |