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EBI DbfetchID AL939128; SV 1; linear; genomic DNA; STD; PRO; 296500 BP. XX AC AL939128; AL023862; AL031013; AL031107; AL031350; AL031371; AL031515; AC AL033505; AL034443; AL035161; AL079355; AL096825; XX DT 25-OCT-2002 (Rel. 73, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 4) XX DE Streptomyces coelicolor A3(2) complete genome; segment 25/29 XX KW . XX OS Streptomyces coelicolor OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Streptomycineae; Streptomycetaceae; Streptomyces. XX RN [1] RP 1-296500 RA Bentley S.D.; RT ; RL Submitted (09-MAY-2002) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Streptomyces sequencing team, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL sdb@sanger.ac.uk XX RN [2] RX DOI; 10.1038/417141a RX PUBMED; 12000953. RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L., RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H., RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E., RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D., RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.; RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor RT A3(2)"; RL Nature 417(6885):141-147(2002). XX DR EMBL-CON; AL645882. DR RFAM; RF00005; tRNA. XX FH Key Location/Qualifiers FH FT source 1..296500 FT /organism="Streptomyces coelicolor" FT /strain="A3(2)" FT /mol_type="genomic DNA" FT /db_xref="taxon:1902" FT CDS complement(144..443) FT /transl_table=11 FT /gene="SCO6480" FT /gene_synonym="SC9C7.16c" FT /product="hypothetical protein SC9C7.16c" FT /note="SC9C7.16c, unknown, len: 99 aa" FT /db_xref="GOA:Q9ZBJ4" FT /db_xref="InterPro:IPR007138" FT /db_xref="UniProtKB/TrEMBL:Q9ZBJ4" FT /protein_id="CAA22728.1" FT /translation="MTYGCIASMKTRPGFREEVVSLLLSAADGLRDAGCELYVVGLSED FT DETTIWVTEVWRTREDHDASLELPAAKDAIGRAMPMLTGEFTKQEMSVAGGLGL" FT CDS complement(517..1563) FT /transl_table=11 FT /gene="SCO6481" FT /gene_synonym="SC9C7.17c" FT /product="conserved hypothetical protein" FT /note="SC9C7.17c, conserved hypothetical protein, len: FT 348aa; similar to several hypothetical proteins eg. FT SW:Y0BN_MYCTU from Mycobacterium tuberculosis (340 aa) FT fasta scores; opt: 998, z-score: 1321.8, E(): 0, (47.6% FT identity in 355 aa overlap)." FT /db_xref="GOA:Q9ZBJ3" FT /db_xref="InterPro:IPR007197" FT /db_xref="UniProtKB/TrEMBL:Q9ZBJ3" FT /protein_id="CAA22729.1" FT /translation="MRWENLTDSDHARAADTALFGADAVVTRTFDTPEFRGITFHEVRA FT RSILNRVPGASRMPFEWTVNPYRGCTHACVYCFARKTHSYLDLDTGLGFDSQIVVKVNA FT PEVLRRQLASRRWQGEHVAMGTNVDCYQRAEGRYRLMPGIIEALTERANPFSILTKGTL FT ILRDLDLLTRAARVTEVGISVSVGFTDAELWRTVEPGTPAPERRLEVVRALGERGIGCG FT VLMAPVIPFLGDEPAQLRATVRAIAAAGATSVTPLVLHLRPGAREWFMAWLGRHHPHLV FT RRYERLYADGAYAPKWYQRRITRQVHDLAREYGIGPARAGMPRRVAEPEHSRPAEPAPP FT EPVQLSLI" FT CDS 1800..2243 FT /transl_table=11 FT /gene="SCO6482" FT /gene_synonym="SC9C7.18" FT /product="conserved hypothetical protein" FT /note="SC9C7.18, conserved hypothetical protein, len: 348 FT aa; similar to two hypothetical proteins e.g. TR:O69685 FT (EMBL:AL022121) Mycobacterium tuberculosis RV03718c or FT MTV025.066c, 147 aa; fasta scores; opt: 475, z-score: FT 768.3, E(): 0, (52.1% identity in 146 aa overlap)" FT /db_xref="InterPro:IPR019587" FT /db_xref="UniProtKB/TrEMBL:Q9ZBJ2" FT /protein_id="CAA22730.1" FT /translation="MAQVEATTERIVAADAETVFDTLADYSGTREKLLPEHFSEYEVRE FT GGDGEGTLVHWKLQATSKRVRDCLLEVTEPTDGELVEKDRNSSMVTTWRVTPAGEGKSR FT VVVLTTWQGAGGVGGFFEKTFAPKGLARIYDALLAKLAAEVEK" FT CDS 2394..4841 FT /transl_table=11 FT /gene="SCO6483" FT /gene_synonym="SC9C7.19" FT /product="putative efflux protein" FT /note="SC9C7.19, probable efflux protein, len: 815aa; FT similar to many, several of which are involved in toxin FT /antibiotic efflux eg. TR:O69070 (EMBL:AF061335) FT oxytetracycline exporter from Streptomyces rimosus (536 aa) FT fasta scores; opt: 1020, z-score: 879.9, E(): 0, (36.9% FT identity in 542 aa overlap)." FT /db_xref="GOA:Q9ZBJ1" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9ZBJ1" FT /protein_id="CAA22731.1" FT /translation="MGGITLVQDPVRDPVQDEPVVAAQAPPGPPVPGPDGERDAGLSPR FT RVRLVFVGLMLALLLAALEQMIVATALPKIVGELHGLDKMSWAITAYLLTSTVGLPIYG FT KLGDLFGRKGVFQFAILVFVVGSALAGRAQTMDQLIAFRAVQGVGAGGLMIGVQAIIAD FT IVPPRERARYMGLIGASFGLASVAGPLLGGYFTDHLSWRWCFYINVPFGLVTMAVVAVV FT LKLPRPRVKPRLDILGALLLAAASTCLVLLTSWGGTEYAWGSRVILGLAAGAVAATLLF FT LVAEHFAPEPLIPLRLFRDSIFNVTALVGLVVGVALFGAASYLPTFLQMVDGASATESG FT LLMLPMMGGVVGASIISGQLISRTGHYRIHPILGSALSVVGMWLLSRLDADTSRLHYSI FT WMAVLGAGIGLVMPVLVLAVQNSVRPTDLGTATSANNYFRQIGGSVGAAVFGTLFAGRL FT TDALADRIPAEAGVGLPDAEAITPQLVHSLPPALRDAYIGAYADAMPRIFLYLVPVLVL FT GLLIALFLKEKPLVSHNAPVTDPETAPHAPQPQPAAQVPPARSPYAGGIPVCGTVQHPD FT GTVVPRAALTLIDVGGQQIGRGASGDDGRYALATPGSGAYVLIAAAGGHQPQAVSVTVG FT ERPVELDVVLGGAGRLAGSVMTADGSPVRDATVTLTNVHGEVVATTRSGREGGYVITEL FT VAGEYTLAASAPAFRPAALPVSVQAARETRQDVELAGGAVLRGTVRASGGRAVEDARVT FT LLDAAGNVVDTLTTGPDGTFRFVDLSSGEYTVIAAGYPPVATVLQVAGGGRTERDLQLG FT HED" FT CDS 4911..7493 FT /transl_table=11 FT /gene="SCO6484" FT /gene_synonym="SC9C7.20" FT /product="conserved hypothetical protein" FT /note="SC9C7.20, conserved hypothetical protein, len: FT 860aa; similar to many hypothetical proteins egs. TR:O86875 FT (EMBL:U22894) from Streptomyces lividans (547 aa) fasta FT scores; opt: 1000, z-score: 738.2, E(): 0, (40.0% identity FT in 497 aa overlap) and TR:O86807 (EMBL:AL031031) from FT Streptomyces coelicolor (916 aa) fasta scores; opt: 358, FT z-score: 316.9, E(): 2.3e-10, (27.2% identity in 779 aa FT overlap). Also contains a short region of similarity to FT TR:Q53897 (EMBL:X60316) AbaA regulatory locus from FT Streptomyces coelicolor (192 aa) fasta scores; opt: 108, FT z-score: 223.2, E(): 3.8e-05, (38.5% identity in 135 aa FT overlap)." FT /db_xref="GOA:Q9ZBJ0" FT /db_xref="HSSP:1LT0" FT /db_xref="InterPro:IPR010822" FT /db_xref="UniProtKB/TrEMBL:Q9ZBJ0" FT /protein_id="CAA22732.1" FT /translation="MVTGHPRTVVTATQILRSRGQRGPDAMDHGTERDAPPGHRAGPDT FT VPADPVTGRVPLAVVVVDRDGLVSHWSRGARRLFALSKEEAIGRPAPDLLPVSGVLPED FT AEPDGAGHDDSYRSYTAHDGPGPGLESSLDGRLSYPAAGRARLTVRADDRVDVLWWAYP FT LVGPGPERLLVLAADADGLRRDYADGTDDSAGPAVVERIAPAFALHTDFPGADELARRL FT PEILPSMSVGESARIVAQVLELGYPVLEFSQHDRVPVTPDWGVPRRAERRARRERAARA FT LAAGEPVPDELRDEAEDLEYAAVRERLEFLNEVSGAIGTSLDLSRTIVEVSRAVVPRFT FT DVAGTYLREQVVAGEGFPDGVPDTTTMWHRVALEHTDEPGRWDDVVPVGEAMPFPAHTP FT FFQCMTTGEPVLVPRITEEMGHAIASQFEKRDIRPLITGRSMLLVPLKARTVVLGFMIL FT LRHPERPVFNDMDRVTGAELAARAGLVLDNARMYTHQENVAETLQDSMLPHIPARLAGC FT DIATRYLPGTLLGRVGGDWFDAVKLPGARTALVVGDVMGHGLNSAAMMGQLRTAVQTMA FT GLDLPPAQLLRNLDDLAQRLGDTHLATCLYAVYDPIAGELHLANAGHIPPVLVRAEDGA FT SELIDLPTGAPIGVGGVPFESVRVTVAPGDRLVMCTDGLVEVRGEDIGVGLATLCESAA FT HPAASMDDACDTIIRALGAGGGRKDDVALLMARLTGIEPDAVAEWRLARDPAEVGRARA FT AVREQLYDWGLPKLVAPAELMVSELVTNAVRHSHARPVALRLVRADTLLCEVDDDDHEL FT PALKSAGPGDETGRGLRVVSTLAREWGASRTGAGKTVWFELTLPARHR" FT CDS 7711..8433 FT /transl_table=11 FT /gene="SCO6485" FT /gene_synonym="SC9C7.21" FT /product="hypothetical protein SC9C7.21" FT /note="SC9C7.21, unknown, len: 240 aa" FT /db_xref="InterPro:IPR013217" FT /db_xref="UniProtKB/TrEMBL:Q9ZBI9" FT /protein_id="CAA22733.1" FT /translation="MSVTSRYRDAWEGFWNEASGDRGAVFWDAEPTLTAGRHLAHFEPH FT LTDAALPLIDLGCGNGTQTRYFAERFPHVVGADLSAAALAHARHADPGGLAAYRQLDAA FT DKAEAQALHAELGDANVYVRGVLHQCEPDDRQPLADALAALLGERGRAFLVEPSQAAKT FT VLMGLAQGPAGPPAKLAPVLRHGLTPGAVPDEAVPEYLRAAGLTVLASGELPLVTTEYT FT ADGTRIELPSAWVVAGTA" FT CDS 8603..9436 FT /transl_table=11 FT /gene="SCO6486" FT /gene_synonym="SC9C7.22" FT /product="putative transport associated protein" FT /note="SC9C7.22, possible transport associated protein, FT len: 277aa; similar to SW:DPPA_BACSU dppA, dipeptide FT transport protein (274 aa) fasta scores; opt: 448, z-score: FT 604.3, E(): 2.3e-26, (32.3% identity in 269 aa overlap)." FT /db_xref="HSSP:1HI9" FT /db_xref="InterPro:IPR007035" FT /db_xref="UniProtKB/TrEMBL:Q9ZBI8" FT /protein_id="CAA22734.1" FT /translation="MKILISADMEGATGVTWPADVLPGTPQWERCRSMFTSDVNAAVLG FT FFDGGADEVLVNEAHWSMRNLLLERLDERTEMLTGRHKALSMVEGVQHGDVDGIAFIGY FT HAGAGMEGVLAHTYLANQLTGVWLNDVRASEGLLNAHVVAEYGVPVVLVTGDDVACEDA FT LGYAPEARKVAVKDHVSRYAAVCRTPARTAADIRAAAKEAAALAVRHEPVGGGPFTLAM FT EFDAEHLAAAATVVPGVAQVGERKVAYTHETMFEAIRTFKAVTTIVSAAVEEQYG" FT CDS 9429..10760 FT /transl_table=11 FT /gene="SCO6487" FT /gene_synonym="SC9C7.23" FT /product="putative aminoacylase" FT /note="SC9C7.23, possible aminoacylase, len: 443aa; similar FT to many aminoacylases and hypothetical proteins egs. FT TR:O06234 (EMBL:Z95388) hypothetical protein from FT Mycobacterium tuberculosis (448 aa) fasta scores; opt: FT 1278, z-score: 1467.2, E(): 0, (47.2% identity in 449 aa FT overlap) and SW:ACY1_PIG aminoacylase I from Sus scrofa FT (pig) (406 aa) fasta scores; opt: 294, z-score: 340.6, E(): FT 1.1e-11, (27.3% identity in 421 aa overlap). Contains FT PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family FT signature 1." FT /db_xref="GOA:Q9ZBI7" FT /db_xref="InterPro:IPR011650" FT /db_xref="UniProtKB/TrEMBL:Q9ZBI7" FT /protein_id="CAA22735.1" FT /translation="MAEHTGTGPDTGEQALDEVVRFTSELIRIDTTNRGGGDCQERPAA FT EYAAARLAEAGIEPTLLERTAGRTNVVARIEGTDPSADALLVHGHLDVVPAEAADWSVH FT PFSGEIRDGVVWGRGAVDMKNMDAMILAVVRDWARRGVRPRRDVVIAFTADEEASAEDG FT SGFLADRHAALFEGCTEGVSESGAFTFHDGAGRQFYPIAAGERGTGWLKLTARGRAGHG FT SKVNRENAITRLAAALTRIGDHAWPLRLTPTVRAALTEIAGVYGIETDLSDVDALLDKL FT GQAGKLVESTVRNSTNPTMLDAGYKVNVIPGEAVAHVDGRFLYGAEDEFRSTLDRLTGP FT DVDWEFVHREVALQAPVDSPTYARMRAAVEEFAPEGHVVPYCMSGGTDAKQFSRLGITG FT YGFAPLKLPEGFDYQALFHGVDERVPVEALHFGVHVLDRFLRTA" FT misc_feature 9681..9710 FT /note="PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family FT signature 1." FT CDS 10803..12770 FT /transl_table=11 FT /gene="SCO6488" FT /gene_synonym="SC9C7.24" FT /product="putative acyl-peptide hydrolase" FT /note="SC9C7.24, possible acyl-peptide hydrolase, len: FT 651aa; similar to many acyl-peptide hydrolases and FT hypothetical proteins egs. TR:Q55413 (EMBL:D64003) FT hypothetical protein from Synechocystis sp. (strain PCC FT 6803) (637 aa) fasta scores; opt: 1306, z-score: 1326.5, FT E(): 0, (39.6% identity in 647 aa overlap) and TR:P70479 FT (EMBL:X14915) acyl-peptide hydrolase from Rattus norvegicus FT (rat) (729 aa) fasta scores; opt: 258, z-score: 199.2, E(): FT 0.00083, (28.2% identity in 234 aa overlap)." FT /db_xref="GOA:Q9ZBI6" FT /db_xref="InterPro:IPR001375" FT /db_xref="UniProtKB/TrEMBL:Q9ZBI6" FT /protein_id="CAA22736.1" FT /translation="MGESVRTLSYGSWPSPVDAALAAAHDGRPDDVGFVGDEVWWTAPR FT PTEGGRRTLVRRHADGTEEPVLPAPWNVRSRVIEYGGRPWGAATTDSGPLVVFVNFADQ FT RLYAFTPGGGEPRPLTPLSAVGGGLRWIEPDPRPERGEVWCVLEEFTGEGPTDVRRVPV FT AVPLDGSAADDRGAVRELAPERHRFVTGPRLSPDGRRAAWLAWDHPRMPWDGTELIVAE FT VGPEGTFQAARTVAGGPEESIAQADWAPDGTLLYASDRTGWWNLYRDGRPLCPREEEFG FT GPLWKLGQRWFAPLDSGLIAVLHGRGAAVLGILDPETGEVVDAAGPWTEFAPALAAHGE FT RVAAVGASPRSGYEVVELDARTGRARVIGAPHEDATDPEFYPRPRIRTFTGPGGREIHA FT HVYPPHHPGCRAPDGELPPYVIWAHGGPTSRSPLVLDLEIAYFTSRGIGVAEVNYGGSS FT GHGREYRNRLREQWGVVDVEDCAAVALALADEGTADRARLAVRGGSAGGWTSAASLATT FT DVYACGTISYPILDLTGWGTGETHDFESQYLESLIGPYAEVPDRYTDRSPAEHAERVTA FT PFLLLQGLDDVICPPVQCERFLDRMAGRGVPHAYLAFEGEGHGFRRAETMVRALEAELS FT LYAQVFGLTPPGVPVLELTR" FT CDS 12776..13708 FT /transl_table=11 FT /gene="SCO6489" FT /gene_synonym="SC9C7.25" FT /product="conserved hypothetical protein" FT /note="SC9C7.25, conserved hypothetical protein, len: 310 FT aa; similar to several proteins of undefined function egs. FT TR:P74220 (EMBL:D90913) hypothetical protein from FT Synechocystis sp. (strain PCC 6803) (301 aa) fasta scores; FT opt: 642, z-score: 649.7, E(): 6.7e-29, (38.8% identity in FT 309 aa overlap) and TR:Q47511 (EMBL:X57583) MccF protein FT from Escherichia coli plasmid pMCCC7 thought to be involved FT in self-immunity to translation inhibitor microcin C7 (344 FT aa) fasta scores; opt: 178, z-score: 259.5, E(): 3.6e-07, FT (25.1% identity in 339 aa overlap)" FT /db_xref="GOA:Q9ZBI5" FT /db_xref="InterPro:IPR003507" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZBI5" FT /protein_id="CAA22737.1" FT /translation="MRELVRPARLAPGARVAVVAPSGPVPEERLQAGLDVLRGWDLDPV FT VAPHVLDRHDTFDYLAGTDADRAADLQAAWCDPAVDAVLCARGGYGVQRMADLLDWEAM FT RAAGPKVFVGFSDITALHEAFATRLGLVTLHGPMAAGIDFIKNARAQEHLRATLFAPET FT VRVITSGGTPLVPGRARGVTLGGCLALLAADLGTPHARPGARGGLLCLEDVGEETYRID FT RYLTQLLRSGWLDGVGGVLLGSWAQCEPYERLRPLLADRLGGLGVPVVEDFGFGHCEGA FT LTVPFGVPAELDADTGTLTLDRPALCSPG" FT CDS 13718..14317 FT /transl_table=11 FT /gene="SCO6490" FT /gene_synonym="SC9C7.26" FT /product="putative acetyltransferase" FT /note="SC9C7.26, possible acetyltransferase, len: 199 aa; FT similar to SW:RIMJ_ECOLI ribosomal-protein-alanine FT acetyltransferase from Escherichia coli (194 aa) fasta FT scores; opt: 248, z-score: 351.1, E(): 2.9e-12, (38.7% FT identity in 111 aa overlap)." FT /db_xref="GOA:Q9ZBI4" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9ZBI4" FT /protein_id="CAA22738.1" FT /translation="MPHTPPRHLAEGPRVGIRHFSHADAAEFTARARQSKDLHHPWLFP FT PESVQAYEAYAARLIEDRTKAGFLVCEKDTEATDGAGGPAGPVPDGGSIAGFVNINNIV FT EGGFLSGALGYGAFAHAAGRGLMREGLDLVVRYAFGPMRLHRLEINVQPGNAASIALAR FT ACGFHLEGFSPRMLYIDGAWRDHQRWAITAETVTSG" FT misc_feature 13766..14221 FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 17.00, E-value FT 0.022" FT CDS complement(14289..14681) FT /transl_table=11 FT /gene="SCO6491" FT /gene_synonym="SC9C7.27c" FT /product="hypothetical protein SC9C7.27c" FT /note="SC9C7.27c, unknown, len: 130aa" FT /db_xref="UniProtKB/TrEMBL:Q9ZBI3" FT /protein_id="CAA22739.1" FT /translation="MNERHGNEQHGNERHVNERHTYRVIVRGTWEGLTEDARARLLAEA FT GEHGMASMRFTEEGSLSYEPAPLKHFSMRYVVVSDAADGEEMAGAIAEDRAEGALRGLG FT YGFGDLKSTVTDLDTMKINRKSRSRR" FT CDS 14832..16829 FT /transl_table=11 FT /gene="SCO6492" FT /gene_synonym="SC1E6.01" FT /gene_synonym="SC9C7.28" FT /product="hypothetical protein" FT /note="SC1E6.01, unknown, partial CDS, len: >616 aa, some FT similarity to hypothetical protein YPHG_ECOLI (1124 aa), FT fasta scores; opt: 360 z-score: 279.9 E(): 2.6e-08, 27.1% FT identity in 310 aa overlap" FT /note="SC9C7.28, partial CDS, unknown, len: 83 aa; FT constitutes the N-terminus of TR:E1341375 (EMBL:AL033505) FT hypothetical protein from Streptomyces coelicolor." FT /db_xref="InterPro:IPR011717" FT /db_xref="UniProtKB/TrEMBL:Q8CJM7" FT /protein_id="CAD55378.1" FT /translation="MTTIRREVLTLPAAPLGPDNPLPPLRPLDEAHRIDDRDRAGLPRD FT MARQIDYEPLRSLLPAQVRDGYGRGREPRALDALVIENDRLRATVLPALGGRIASLHHK FT PTDRELLYVNPVLQPANFALNGAWFSGGIEWNIGATGHTTLSCSPVHAACVPAPDGGRM FT LRLWEWERLRDLPFQVDLWLPEGSDFLYVGARIRNPHERPAPTYWWSNIAVPENRRVLA FT PADEAWLPHSPKGVGGAPIGYERRLRRVPVPEYGGVDRTYPLNSTYAADYFYEVPDDRR FT RWIAALDEGGHGLVQTSTDLLRGRKLFVWGTGPGGRRWQEWLTEPGTGGYCEIQAGLVR FT TQLEHVKLEAESEVSWLEAYGPLTASPEGDWHTVLRRAEDRLEAALPRADVDAAYDAWR FT ACADTEPGERLATGSGWGALEVLRTGWKLPGTPFAEDTLGEEQRPWLHLLRAGSLPEPE FT HHAPPGGTLVARPWRDMLETAAATPSAEYHLGVAQWHGGDRAQAVRSWERGLKSATDRW FT PLLRCLAVADQEDGHGERAADQYAEAFDDLCARRTDGAEKGDGRWVAVTAALGREAIGA FT LLAAGRGTDARTVWDRLDPATRARGRYRLIEAELLAAEGRSEDARAVFDEGFEVADLRE FT GADGIGLLWARLDDAPLPARYDFRMWPDGE" FT misc_feature 14978..15081 FT /note="Real overlap with SC1E6 (EMBL:AL033505) Streptomyces FT coelicolor cosmid 1E6." FT CDS complement(16861..17208) FT /transl_table=11 FT /gene="SCO6493" FT /gene_synonym="SC1E6.02c" FT /product="hypothetical protein SC1E6.02c" FT /note="SC1E6.02c, unknown, len: 115 aa" FT /db_xref="UniProtKB/TrEMBL:Q9ZC20" FT /protein_id="CAA22030.1" FT /translation="MDILGATLRIYVDDLDKAIPFYEGLAGGEALRFERGGVQAAAIGC FT FLLMSGPESQLEVLRKVAATIAVSDVEETRHVLGSLGADIIAGPVATPGGRNLIARHPD FT GAIYEYVDRQQ" FT CDS 17223..17840 FT /transl_table=11 FT /gene="SCO6494" FT /gene_synonym="SC1E6.03" FT /product="putative membrane protein" FT /note="SC1E6.03, putative membrane protein, len: 205 aa; FT contains two possible transmembrane domains in centre" FT /db_xref="InterPro:IPR009937" FT /db_xref="UniProtKB/TrEMBL:Q9ZC19" FT /protein_id="CAA22031.1" FT /translation="MGRPGAHPRSGHGSPAGGYPQPMDRMDHLEHLDRQLVDELAQVAR FT ETVRDELREQTRRQRRKATLYAASGTAALYAGAAVALAVGLALALALPGWAAALITAAL FT LAVVAYLLRGAARPHPSRPGPAPGTAGHDHVAGHDHVAGGGAPAAAPGGLGVPYPPMPP FT VAPGGVGGATGAPGAGTPAPGGTGPAAPRQDDLDPENKRRRG" FT stem_loop 17868..17912 FT /note="hairpin loop with 20 bp stem" FT CDS complement(17926..18888) FT /transl_table=11 FT /gene="SCO6495" FT /gene_synonym="SC1E6.04c" FT /product="putative dehydrogenase" FT /note="SC1E6.04c, probable dehydrogenase, len: 320 aa; FT similar to Mycobacterial F420-dependent glucose-6-phosphate FT dehydrogenases e.g. M. smegmatis TR:O68447 (EMBL:AF041061) FT F420-dependent glucose-6-phosphate dehydrogenase (336 aa), FT fasta scores; opt: 499 z-score: 362.9 E(): 6.2e-13, 33.2% FT identity in 331 aa overlap" FT /db_xref="GOA:Q9ZC18" FT /db_xref="InterPro:IPR019945" FT /db_xref="UniProtKB/TrEMBL:Q9ZC18" FT /protein_id="CAA22032.1" FT /translation="MPEYGYFLSCEQYGPAELIEQARMAEQAGFQALWISDHYHPWNGE FT QGQSPFVWSVIGALSDAVSLPIETAVTCPTVRIHPAVVAQAAATSAVMTDGRFRLGVGT FT GEALNEHIFGDAWPAAHVRLEMLEEAILIMRRLLTGEEVNHHGTHYTVENARLYTVPDE FT PVPIDISGFGPAATKLAARVGDGYITMMPDASMVEQYRKGGGGGKLVSGGTKVCYDTDK FT DAAVRTVHRLWANEQLPGELGQVLPSPKHFEQAQTLVTEDMVRDSRVCGDDVDEHVAEL FT KQFADAGFDRVYVNQIGPDLRGFFDLYRTKVLPQLQQSA" FT CDS 19075..20964 FT /transl_table=11 FT /gene="SCO6496" FT /gene_synonym="SC1E6.05" FT /product="putative dehydrogenase" FT /note="SC1E6.05, probable dehydrogenase, len: 629 aa; FT similar to e.g. Mycobacterium smegmatis TR:O52473 FT (EMBL:AF038423) NADH dehydrogenase (457 aa), fasta scores; FT opt: 499 z-score: 263.3 E(): 2.2e-07, 31.2% identity in 417 FT aa overlap. Contains 6x degenerate repeats of the sequence FT KNQPGGEP(A /G)= (P-loop)" FT /db_xref="GOA:Q9ZC17" FT /db_xref="InterPro:IPR013027" FT /db_xref="UniProtKB/TrEMBL:Q9ZC17" FT /protein_id="CAA22033.1" FT /translation="MSRPRIVIVGAGFAGYRTARTLSRLTRHQADITLLNPTDYFLYLP FT LLPQVAAGILEPRRVSVSLSGTLPHVRLVLGEADGIDLDGRTVHYTGPEGGEGTLAYDR FT LVLAAGSVNKLLPIPGVAEHAHGFRGLPEALYLRDHVTRQVELAAAADDRAECAARCTF FT VVVGAGYTGTEVAAHGAMYTDAQVRRHPMRTGMRPRWMLLDVAPRVMPEMDERLSRTAE FT RVLRQRGVDVRMGTSVKEATHDGVVLTDGSTVDTRTLVWCVGVRPDPLVESLGLPMERG FT RLLVDPHLQVPGRPELFACGDVAAVPDLNQPGQYTPMTAQHAWRHGKVCAHNVVASLGR FT GQRRAYRHRDMGFVVDLGGAKAAANPLGLPMSGPAAGAVTRGYHLAAMPGNRVRVAADW FT LLDAVLPRQAVQLGLVRSWSVPLESSSPEVARVPGRPEQSGKDAGTAGSAGTAGKHADG FT DEGKKQPGGEPAKGQPGGEPGKNQPGGEPGKNQPGGEPGKNQPGGEPAKNQPGGEPAER FT GPDASAGSRSHGERAKRSQSGSPRASGKPRRAVEAAGPRSARGGSGKPGKSSRASGTGS FT AGKRPTAPSGPSRSAGQPADPGPEPPAHQPPPGPDIAPGPVRRTDGRAVEGDS" FT repeat_region 20434..20622 FT /note="6x27 bp imperfect repeat" FT misc_feature 20755..20778 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT CDS 20961..22808 FT /transl_table=11 FT /gene="SCO6497" FT /gene_synonym="tktA2" FT /product="transketolase A" FT /note="SC1E6.06, tktA2, probable transketolase, len: 615 FT aa; highly similar to eukaryotic transketolases e.g. FT TKT_HUMAN transketolase (EC 2.2.1.1) (623 aa), fasta FT scores; opt: 1909 z-score: 2169.3 E(): 0, 50.0% identity in FT 614 aa overlap; less similar to prokaryotic transketolases FT e.g. TKT_RHOSH transketolase (657 aa), fasta scores; opt: FT 477 z-score: 830.4 E(): 0, 31.3% identity in 635 aa FT overlap. Contains PS00802 Transketolase signature 2 and FT Pfam match to entry PF00456 transketolase, Transketolase, FT score 397.70, E-value 1.1e-115. Also similar to S. FT coelicolor tkt (SC5A7.13c) E(): 4.2e-20, 29.0% identity in FT 679 aa overlap" FT /db_xref="GOA:Q9ZC16" FT /db_xref="HSSP:1IK6" FT /db_xref="InterPro:IPR005475" FT /db_xref="UniProtKB/TrEMBL:Q9ZC16" FT /protein_id="CAA22034.1" FT /translation="MNTGELVDLGQQLRVDSVRAAAAAGSGHPTSSMSAADLMAVLLAN FT HLRYDFERPAHPGNDRFVLSKGHASPLLYSAFKAAGAIDDEELLTFRKQGSRLEGHPTP FT QRLPWVETATGSLGQGLPVGVGIALSGKRLDHTDYRVWVLCGDSELAEGSIWEAAEHAG FT HEHLDNLTVIVDVNRLGQRGPTRHGHDLDAYARRFRAFEWHTIEVDGHDVDAVDRAYGE FT ALSTKGQPTAIIARTLKGKGVRAVEDREGQHGKPLPEAEEAVAELGGPRDIRVRVHAPE FT DARSLRSTGTGQTELPRYGLGDEVATRNAFGEALAAVGTARGDVVALDGEVGDSTRAEF FT FAKEHPERYFECYIAEQQMVAAAVGMAARGWVPFATTFAAFLTRAYDFVRMASISGAGI FT NLVGSHAGVAIGQDGPSQMGLEDLAMMRAIHGSTVLYPCDANQAARLVAEMAGLEGIRY FT LRTSRGESKVIYGPDEEFPVGGSKVLRSSDADRLTVVAAGVTLHEALAAADALGADGIP FT VRVIDLYSVKPVDRATLRAAAEETGCLVTVEDHRREGGIGDAVLDAFSDGRPVPRLVRL FT AVTTMPGSATPAEELHAAGIDAESIEAAARMLVEQAIVP" FT misc_feature 20991..22763 FT /note="Pfam match to entry PF00456 transketolase, FT Transketolase, score 397.70, E-value 1.1e-115" FT misc_feature 22191..22241 FT /note="PS00802 Transketolase signature 2" FT CDS 22805..23764 FT /transl_table=11 FT /gene="SCO6498" FT /gene_synonym="SC1E6.07" FT /product="conserved hypothetical protein SC1E6.07" FT /note="SC1E6.07, unknown, len: 319 aa; similar to FT hypothetical protein from Mycobacteria e.g. TR:O69697 FT (EMBL:AL022121) MTV025.078C (346 aa), fasta scores; opt: FT 537 z-score: 578.0 E(): 6.5e-25, 34.9% identity in 292 aa FT overlap" FT /db_xref="GOA:Q9ZC15" FT /db_xref="InterPro:IPR014145" FT /db_xref="UniProtKB/TrEMBL:Q9ZC15" FT /protein_id="CAA22035.1" FT /translation="MTGSGGTGGGGRGGGARTVRAGRHTVEVHRPDKVLFPVGEGGTEE FT YTKGDLVDYHRAAAPFMLPHLRGRPLMLERHPDGVDGPRFMQKNTPEHYPEWIDRVEVG FT KEGGTVCHTVCDDSATLVYLADQAALTLHRWLSRTGRLDRPDRMVFDLDPAQDDFEAVR FT AAARLLAGLLDELKLPSAPMTTGSRGLHVVVPLDGRQDFDDVREFARAVADVLAAAHPD FT RLTTAARKKDRGDRLYLDIQRNAYAQTAVAPLTVRARPGAPVATPISWDQLDDPALHAR FT RWTVADAVEQARTRPWAGIMNSPRALGPARRRLNALHG" FT CDS 23830..24222 FT /transl_table=11 FT /gene="SCO6499" FT /gene_synonym="gvpO" FT /product="putative gas vesicle synthesis protein" FT /note="SC1E6.08, gvpO, probable gas vesicle synthesis FT protein, len: 130 aa; similar to several from Halobacteria FT e.g. GVO1_HALSA GVPO protein, plasmid (120 aa), fasta FT scores; opt: 167 z-score: 285.9 E(): 1.2e-08, 30.2% FT identity in 106 aa overlap. Contains 9x degenerate QXS FT repeat near N-terminus and apparent helix-turn-helix motif FT at aa 53-74 (Score 1244, +3.42 SD)" FT /db_xref="GOA:Q9ZC14" FT /db_xref="InterPro:IPR008634" FT /db_xref="UniProtKB/TrEMBL:Q9ZC14" FT /protein_id="CAA22036.1" FT /translation="MSNTKNTSDSQESQQSSRKPQRSQATQTSQASQKSQSSQEPRRPK FT PMEVLREARAQLAELTGMTAESVSSFEQTEEGWVLEVEVLELERVPDTMSLMASYQVEL FT DAEGQLTGYRRARRYERGRADSRGGR" FT CDS 24294..24728 FT /transl_table=11 FT /gene="SCO6500" FT /gene_synonym="gvpA" FT /product="putative gas vesicle synthesis protein" FT /note="SC1E6.09, gvpA, probable gas vesicle synthesis FT protein, len: 144 aa; highly similar in N-terminus to many FT e.g. GVPA_PSEAN gas vesicle protein (71 aa), fasta scores; FT opt: 219 z-score: 363.2 E(): 6e-13, 65.4% identity in 52 aa FT overlap. Contains PS00234 Gas vesicles protein GVPa FT signature 1 and Pfam match to entry PF00741 Gas_vesicle, FT Gas vesicle protein, score 44.20, E-value 2.9e-09" FT /db_xref="GOA:Q9ZC13" FT /db_xref="InterPro:IPR018493" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZC13" FT /protein_id="CAA22037.1" FT /translation="MTVVPAQQTGGGGSSGLYDVLELVLDRGLVIDAFVRVSLVGIEIL FT KIDVRVVVASVDTYLRFAEACNRLDLEAGPRKDPGLPDLVGEMTESGARGKSKGALSGA FT AETISDAFKQARDDGGSERETSSRPRARKAAPSRRKEEQE" FT misc_feature 24339..24455 FT /note="Pfam match to entry PF00741 Gas_vesicle, Gas vesicle FT protein, score 44.20, E-value 2.9e-09" FT misc_feature 24342..24386 FT /note="PS00234 Gas vesicles protein GVPa signature 1" FT CDS 24725..25498 FT /transl_table=11 FT /gene="SCO6501" FT /gene_synonym="gvpF" FT /product="putative gas vesicle synthesis protein" FT /note="SC1E6.10, gvpF, probable gas vesicle synthesis FT protein, len: 257 aa; some similarity to GVF2_HALSA GVPF FT protein, chromosomal (217 aa), fasta scores; opt: 143 FT z-score: 191.0 E(): 0.0023, 27.1% identity in 247 aa FT overlap" FT /db_xref="GOA:Q9ZC12" FT /db_xref="InterPro:IPR009430" FT /db_xref="UniProtKB/TrEMBL:Q9ZC12" FT /protein_id="CAA22038.1" FT /translation="MSTYVYGITAATHPSLPEGTGGVGDPPREVRILKEGELAAVVSDA FT PEGLRPKRRELLAHQNVLSEIGADGCVLPMRFGSVAPDDKAVTSVLAERAEHYAERLGA FT LDGRVEYNIKANHVEEAVLHHVMAENPEIRALAESNRQAGGGTYETKIQLGEMVAAAVK FT DQEAGDAKALERALEAAADAVSVGPESTGWLANVSFLVKREAADEFLAAVERARGRMPH FT LEVRVNGPLPPYSFVEPGPAEPAGTAAGGADAGAG" FT CDS 25503..25766 FT /transl_table=11 FT /gene="SCO6502" FT /gene_synonym="gvpG" FT /product="putative gas vesicle synthesis protein" FT /note="SC1E6.11, gvpG, probable gas vesicle synthesis FT protein, len: 87 aa; simlar to e.g. TR:O68673 FT (EMBL:AF053765) gas vesicle protein GVPG (88 aa), fasta FT scores; opt: 152 z-score: 269.8 E(): 9.5e-08, 49.1% FT identity in 53 aa overlap. Contains probable coiled-coil FT from aa 37 to 76" FT /db_xref="InterPro:IPR007804" FT /db_xref="UniProtKB/TrEMBL:Q9ZC11" FT /protein_id="CAA22039.1" FT /translation="MGLISEVLLLPFAPVRGGGWAIRQVLEEAERIYYDPATVRAELAR FT LEEQLEAGEITEEEFDRQEDELLDRLEIATRTSAGLGNGTAP" FT CDS 25763..26482 FT /transl_table=11 FT /gene="SCO6503" FT /gene_synonym="SC1E6.12" FT /product="hypothetical protein SC1E6.12" FT /note="SC1E6.12, unknown, len: 239 aa; contains highly FT acidic repetitive stretch between aa 120-180 and highly FT basic repetitive stretch between aa 180-239" FT /db_xref="UniProtKB/TrEMBL:Q9ZC10" FT /protein_id="CAA22040.1" FT /translation="MNRVGLGLAIGAGYLLGRTKKLKMAVAVGTMVAGKKLNLTPKGIA FT ELVSGQLQNNPQFKEIGDQLRTDLRGVGKAASGAMVERQIDALADRLHGRTAEVRDQLS FT GVASRAPGTGSDDSDDSRDSEASEDSEYEEAREREEPEEHQDAEEPQQAEESEESEESE FT ERRAPRRARPAKKASPETRGTAGKAPAKKAAAKAPAKKAAAKRAQPAKKAAGKKTAGAR FT NAARGAGARRSKDGGER" FT repeat_region 26108..26254 FT /note="9bp imperfect repeats" FT CDS 26479..27609 FT /transl_table=11 FT /gene="SCO6504" FT /gene_synonym="SC1E6.13" FT /product="conserved hypothetical protein SC1E6.13" FT /note="SC1E6.13, unknown, len: 376 aa; some similarity in FT part to YMEL_STRLN Streptomyces lincolnensis hypothetical FT protein (150 aa), fasta scores; opt: 377 z-score: 448.8 FT E(): 1e-17, 36.1% identity in 144 aa overlap. Contains FT highly acidic repetitive region from aa 290-376" FT /db_xref="InterPro:IPR005031" FT /db_xref="UniProtKB/TrEMBL:Q9ZC09" FT /protein_id="CAA22041.1" FT /translation="MSDSLGSAASTAGKAAKKNPLADVAQSEAADRLKAEVQDYLAAQA FT TRLLTGVGTKLGETTGKLNDIAEGNSPGFAKLALDGGRKLAEGKSPMRAAFEVGAGKVK FT DNVVGAFKNLTGGKGRKKGGGGQKPTVIIEYVDVGVPLRTAYDQWTQYQDFSTFAKGVK FT SANRADDTSSDWQLKVLWSNRSWKATTTEQVPDDRISWTSEGAKGSTKGVVSFHELAAN FT LTRVVLVIEYYPKGLFEKTGNIWRAQGRRARLDLKNYVRHITFKGEADDGWRGEIRDGE FT VVRSHEDAVAEEEEERQAEQEPEQEPEQEPEGEYDEEAEGEPEEEYEEAAESEYAEPEE FT DEAPEEDKEAGEDEYASGDEDEDEYEYEDAEGGSRR" FT repeat_region 27352..27591 FT /note="9bp imperfect repeats" FT CDS 27606..27935 FT /transl_table=11 FT /gene="SCO6505" FT /gene_synonym="gvpJ" FT /product="putative gas vesicle synthesis protein" FT /note="SC1E6.14, gvpJ, probable gas vesicle synthesis FT protein, len: 109 aa; similar to e.g. TR:O68669 FT (EMBL:AF053765) gas vesicle protein GVPJ from Bacillus FT megaterium (100 aa), fasta scores; opt: 358 z-score: 597.2 FT E(): 5.5e-26, 61.6% identity in 86 aa overlap. Contains FT PS00234 Gas vesicles protein GVPa signature 1 and Pfam FT match to entry PF00741 Gas_vesicle, Gas vesicle protein, FT score 60.90, E-value 2.8e-14" FT /db_xref="GOA:Q9ZC08" FT /db_xref="InterPro:IPR018493" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZC08" FT /protein_id="CAA22042.1" FT /translation="MTTPSRLPDPYGQGQSANLADILERVLDKGVVIAGDIKINLLDIE FT LLTIKLRLVVASVDKAKEMGIDWWESDPALSSRARHDELTRENAALRERLRELDPGRVP FT REEAP" FT misc_feature 27657..27773 FT /note="Pfam match to entry PF00741 Gas_vesicle, Gas vesicle FT protein, score 60.90, E-value 2.8e-14" FT misc_feature 27660..27704 FT /note="PS00234 Gas vesicles protein GVPa signature 1" FT CDS 27932..28711 FT /transl_table=11 FT /gene="SCO6506" FT /gene_synonym="gvpL" FT /product="putative gas vesicle protein" FT /note="SC1E6.15, gvpL, probable gas vesicle protein, len: FT 504 aa; simialar to e.g. GVL1_HALSA GVPL protein, plasmid FT (281 aa), fasta scores; opt: 111 z-score: 229.0 E(): FT 1.8e-05, 24.2% identity in 264 aa overlap" FT /db_xref="GOA:Q9ZC07" FT /db_xref="InterPro:IPR009430" FT /db_xref="UniProtKB/TrEMBL:Q9ZC07" FT /protein_id="CAA22043.1" FT /translation="MTGLRYVYAVCRPFDAALQSQLAGVADDPPRLLAHGDLVAVVSHV FT PEADFGEEALRARLEDLDWLTATARAHQQVVDALTAVTTPLPLRLATVFRDDSGVRVML FT EEREAAFRRTLDRLDGRVEWGVKVYVEGEPAERPEASAPPAPKPATGRDYLRQRRRQSR FT ANDDLWSRAEQFATGLHAALSERADGARLHAPQNPRLSGAAGRNVLNAAYLVARDASEE FT FVEMVDRTKDDAPGIRVELTGPWAAYSFAGETEEEGS" FT CDS 28708..28890 FT /transl_table=11 FT /gene="SCO6507" FT /gene_synonym="gvpS" FT /product="putative gas vesicle synthesis protein" FT /note="SC1E6.16, gvpS, probable gas vesicle synthesis FT protein, len: 60 aa; similar to parts of several gas FT vesicle proteins e.g. Bacillus megaterium TR:O68671 FT (EMBL:AF053765) gas vesicle protein GVPS (95 aa), fasta FT scores; opt: 163 z-score: 303.6 E(): 1.2e-09, 49.1% FT identity in 57 aa overlap, and TR:O68669 (EMBL:AF053765) FT gas vesicle protein GVPJ (100 aa), fasta scores; opt: 130 FT z-score: 256.8 E(): 5.1e-07, 45.2% identity in 42 aa FT overlap. Contains Pfam match to entry PF00741 Gas_vesicle, FT Gas vesicle protein, score 31.70, E-value 1.7e-05" FT /db_xref="GOA:Q9ZC06" FT /db_xref="InterPro:IPR000638" FT /db_xref="UniProtKB/TrEMBL:Q9ZC06" FT /protein_id="CAA22044.1" FT /translation="MTVVERREIALVDLLDRLLAGGVVITGDVTLRIADVDLVRIDLNA FT LISSVNRNVPSPFGD" FT misc_feature 28735..28851 FT /note="Pfam match to entry PF00741 Gas_vesicle, Gas vesicle FT protein, score 31.70, E-value 1.7e-05" FT CDS 28892..29188 FT /transl_table=11 FT /gene="SCO6508" FT /gene_synonym="gvpK" FT /product="putative gas vesicle synthesis protein" FT /note="SC1E6.17, gvpK, probable gas vesicle synthesis FT protein, len: 98 aa; simlar to e.g. Bacillus megaterium FT TR:O68670 gas vesicle protein GVPK (94 aa), fasta scores; FT opt: 321 z-score: 536.7 E(): 1.3e-22, 50.5% identity in 93 FT aa overlap" FT /db_xref="GOA:Q9ZC05" FT /db_xref="InterPro:IPR007805" FT /db_xref="UniProtKB/TrEMBL:Q9ZC05" FT /protein_id="CAA22045.1" FT /translation="MSEPAEPRKRRLDLEPDTVERDLIKLVLTVVELLRQLMERQALRR FT VDEGDLSEDQEERIGLTLMLLDDRMTELRDRYGLRPEDLNLDLGPLGPLLPRE" FT stem_loop 29170..29207 FT /note="hairpin loop with 18 bp stem" FT CDS complement(29279..29449) FT /transl_table=11 FT /gene="SCO6509" FT /gene_synonym="SC1E6.18c" FT /product="hydrophobic protein" FT /note="SC1E6.18c, small hydrophobic protein, len: 56 aa. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9ZC04" FT /protein_id="CAA22046.1" FT /translation="MVPLLLVLLLAIVLFGIGFAVKVLWWIALAVLVLWLIGFLARGTT FT AGGGRGRWYRW" FT CDS complement(29504..30325) FT /transl_table=11 FT /gene="SCO6510" FT /gene_synonym="SC1E6.19c" FT /product="conserved hypothetical protein SC1E6.19c" FT /note="SC1E6.19c, unknown, len: 273 aa; similar to FT hypothetical proteins e.g. M. tuberculosis TR:O53851 FT (EMBL:AL022004) MTV043.32 (270 aa), fasta scores; opt: 1102 FT z-score: 1628.2 E(): 0, 58.6% identity in 263 aa overlap, FT and in part, to several methyltransferases e.g. PMTA_RHOSH FT phosphatidylethanolamine N-methyltransferase (203 aa), FT fasta scores; opt: 198 z-score: 248.3 E(): 1.5e-06, 37.3% FT identity in 102 aa overlap" FT /db_xref="GOA:Q9ZC03" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:Q9ZC03" FT /protein_id="CAA22047.1" FT /translation="MPKPHETAVYTHGHHESVLRSHTWRTAENSAAYLLGSLRPHMRIL FT DIGCGPGTITADLAERVPEGHVTGVDRSPEIVERARATAAARGLENTGFAVADVHALDY FT PDDTFCVVHAHQVLQHVGDPVRALREMRRVARPGGFIAVRDSDYGAMTWYPASSGMDDW FT LDLYHRVARANGGEPDAGRRLKAWALEAGFTDITATSATWTFTTPEEREWWSGLWADRT FT LASAYAERATEGGHATPERLRAVSAAWRDWGKHPESWFSVLHGEILCRKEA" FT CDS complement(30436..31941) FT /transl_table=11 FT /gene="SCO6511" FT /gene_synonym="SC1E6.20c" FT /product="conserved hypothetical protein SC1E6.20c" FT /note="SC1E6.20c, unknown, len: 501 aa; similar to two FT hypothetical proteins from Rhodococcus erythropolis: FT TR:P72262 (EMBL:Z82004) ORF8 (487 aa), fasta scores; opt: FT 1098 z-score: 762.9 E(): 0, 45.5% identity in 488 aa FT overlap, and TR:P72269 (EMBL:Z82005) ORF8 (487 aa), fasta FT scores; opt: 1060 z-score: 717.1 E(): 1.2e-32, 41.7% FT identity in 487 aa overlap. Contains Pfam match to entry FT PF00781 DAGKc, Diacylglycerol kinase catalytic domain FT (presumed), score 31.00, E-value 1.3e-05" FT /db_xref="GOA:Q9ZC02" FT /db_xref="InterPro:IPR016118" FT /db_xref="UniProtKB/TrEMBL:Q9ZC02" FT /protein_id="CAA22048.1" FT /translation="MSPDVDLTAALPGPHPLRNGFLRLDQRAFEAVASRTWPGADPLLP FT RLSRGANHGVLWFAVGAALAASRTPRARRAAARGLASLGLASLTINTLGKRSVRRPRPV FT LDPVPLVRQLKRQPITTSFPSGHAASAAAFATGVALESPAWGAAVAPVAAAVALSRVYT FT GVHFPSDVLAGAALGAGAAFAVRGLVPTRAQHTPPARPRAEVPALPGGEGLVMVANVGS FT GTSDRVRALCDALPDAEVVECEPGDVRAELEKAAGHARALGVCGGDGTVNAAAEIALRH FT GLPLAVLPGGTLNHFAYDLGVEDVRDLCGALERGEGVRVDVGRFASGGRRGVFLNTFSL FT GVYPELVNERERWSPRIGGWPAGVLAAVRVLRADRHPLEAEVRGRRRPLWMLFAGNGTY FT HRRGLASGRRLDLADGQLDVRVVHGGRRPALRLLSAALAGPLTRSPAHAAVQVPRLRLS FT GVAPGTLMAYDGELTETEGDLTLEKLPEALTVYRPLPGGGLFS" FT misc_feature complement(30967..31305) FT /note="Pfam match to entry PF00781 DAGKc, Diacylglycerol FT kinase catalytic domain (presumed), score 31.00, E-value FT 1.3e-05" FT CDS 32065..33684 FT /transl_table=11 FT /gene="SCO6512" FT /gene_synonym="SC1E6.21" FT /product="ABC transporter ATP-binding protein" FT /note="SC1E6.21, probable ABC transporter ATP-binding FT protein, len: 539 aa; similar to many e.g. TLRC_STRFR FT tylosin resistance ATP-binding protein TLRC (548 aa), fasta FT scores; opt: 449 z-score: 533.0 E(): 2.1e-22, 33.0% FT identity in 542 aa overlap. Contains 2x PS00017 ATP FT /GTP-binding site motif A (P-loop) and 2x Pfam match to FT entry PF00005 ABC_tran, ABC transporters, scores 125.80, FT E-value 8.1e-34, and 69.10, E-value 9.1e-17" FT /db_xref="GOA:Q9ZC01" FT /db_xref="HSSP:1US8" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9ZC01" FT /protein_id="CAA22049.1" FT /translation="MGHLEAAHLEYYLPDGRALLGDVSFRVGEGAVVALVGPNGAGKTT FT LLRLLAGELKPHGGTVAVGGGLGVMRQFVGSVRDETTVRDLLVSVAPPRIREAARAVDT FT AEHAIMTVDDEAAQLTYAQALSDWAEARGYEAETLWDMCTTAALGMPYDKAQWRQVRTL FT SGGEQKRLVLEALLRGTDEVLLLDEPDNYLDVPGKRWLEERLAETRKTVLFVSHDRELL FT ARAAEKIVSVEPGPAGADAWVHGGGFTTFHEARRERFARFEELRRRWDEKHAQLKKLVL FT TLRQAAENSHDMASRYRAAQTRLRKFEEAGPPPEPPREQDIRMRLKGGRTGVRAVTCGQ FT LELTGLMKPFDLEVFYGERVAVLGSNGSGKSHFLRLLAGDDVAHTGDWKLGARVVPGHF FT AQTHAHPELLGRTLLDILWTEHAQDRGAAMSRLRRYELTQQAEQAFDRLSGGQQARFQI FT LLLELQGVTALLLDEPTDNLDLESAEALQEGVEGFEGTVLSVTHDRWFARSFDRYLVFG FT SDGRVRETAEPVWDERRVERAR" FT misc_feature 32152..32769 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporters, score 125.80, E-value 8.1e-34" FT misc_feature 32173..32196 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT misc_feature 33133..33615 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporters, score 69.10, E-value 9.1e-17" FT misc_feature 33154..33177 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT CDS complement(33714..34835) FT /transl_table=11 FT /gene="SCO6513" FT /gene_synonym="SC1E6.22c" FT /product="hypothetical protein SC1E6.22c" FT /note="SC1E6.22c, unknown, len: 373 aa; similar to a FT hypothetical protein from M. tuberculosis TR:O06183 FT (EMBL:Z95387) MTCY1A10.03C (374 aa), fasta scores; opt: 425 FT z-score: 395.8 E(): 9.2e-15, 30.2% identity in 371 aa FT overlap" FT /db_xref="UniProtKB/TrEMBL:Q9ZC00" FT /protein_id="CAA22050.1" FT /translation="MDLAFLHPLYEHQGPWASVYVDLSRHTEDTPHERELTAAAVAREL FT AEQGADDATCRAVREAVDELRHATDPHGRALFACAGQVVLDPALARPPYGGTTADWAPL FT PHVTPLLDLAGEDPVCVVAYIDRKGADFELRSALGSSDAGGVTGRQWPVHRTSSADWSE FT RHFQLRVENTWEHNAAEIADALAVCQEETGADLLILVGDDRERRSVHERLPLRLQERVA FT EASRGAGSRLLDDEVEGLRDDHVRARAREDLDRFLAARSPDDEGRAGAAEGVPALVEAA FT REHRIDELLVIPDAPDTHREVWIGEDADQVAVRRTELKTLGEQNSWSARADDALLRSAV FT MTGAPAISVTPVLPPETSQKAPVGGLGALLRWK" FT CDS 34898..35176 FT /transl_table=11 FT /gene="SCO6514" FT /gene_synonym="SC1E6.23" FT /product="hypothetical protein SC1E6.23" FT /note="SC1E6.23, unknown, len: 92 aa" FT /db_xref="UniProtKB/TrEMBL:Q9ZBZ9" FT /protein_id="CAA22051.1" FT /translation="MNEHDTRDDTMTGVDPGRLDDQQLMKELETIHRTRHDTLLYGSND FT ALRAHNDRMARLEGEWLRRNPRRPVAPGRTREGARERGCGQAAAPGG" FT CDS complement(35258..35800) FT /transl_table=11 FT /gene="SCO6515" FT /gene_synonym="pfpI" FT /product="putative protease" FT /note="SC1E6.24c, pfpI, probable protease, len: 180 aa; FT similar to e.g. PFPI_PYRFU protease I (EC 3.2.-.-) (166 FT aa), fasta scores; opt: 413 z-score: 411.9 E(): 1.2e-15, FT 41.3% identity in 172 aa overlap" FT /db_xref="GOA:Q9ZBZ8" FT /db_xref="HSSP:1G2I" FT /db_xref="InterPro:IPR002818" FT /db_xref="UniProtKB/TrEMBL:Q9ZBZ8" FT /protein_id="CAA22052.1" FT /translation="MRIAFLTAPEGVEQVELTEPWRAAKEAGHDPVLVSTQSGEIQGFD FT HLDKADTFPVDEVVGEISADAFGGLVLPGGVANPDFLRMDEKAVAFVKDFFTQGRPVAA FT ICHAPWTLVEADVVRGRTMTSWPSLRTDLRNAGATWVDEQVQVCDAGDNVLVTSRKPDD FT LEAFCETYLAQFAKAAG" FT CDS complement(35826..36224) FT /transl_table=11 FT /gene="SCO6516" FT /gene_synonym="SC5C7.01c" FT /gene_synonym="SC1E6.25c" FT /product="hypothetical protein" FT /note="SC5C7.01c, unknown, partial CDS, len: >45 aa" FT /note="SC1E6.25c, unknown, partial CDS, len: > 123 aa; FT continuation of SC5C7.01c" FT /db_xref="UniProtKB/TrEMBL:Q8CJM6" FT /protein_id="CAD55379.1" FT /translation="MQRGSDRMSVHRDDEMKHELQGLLRSGHPTRSEEWNDPEPAAEDD FT PDVMYGPVTPGRGPTYLEALRLELARNLTRGSFPAGPRELTRTLRRGNAPDALVEGLDR FT LPHKARYDSVQELAVALTESGRSGSQGA" FT RBS complement(36230..36234) FT /note="possible RBS upstream of SC5C7.01c" FT RBS 36424..36427 FT /note="possible RBS upstream of SC5C7.02" FT CDS 36433..38823 FT /transl_table=11 FT /gene="SCO6517" FT /gene_synonym="SC5C7.02" FT /product="uvrA-like protein" FT /note="SC5C7.02, uvrA-like protein, len: 796 aa; similar to FT Streptomyces peucetius TR:Q54827 (EMBL:L76359) daunorubicin FT resistance protein drrC (764 aa), fasta scores; opt: 2051 FT z-score: 2702.2 E(): 0, 51.1% identity in 775 aa overlap, FT and to many uvrA proteins e.g. UVRA_NEIGO excinuclease ABC FT subunit A (950 aa), fasta scores; opt: 412 z-score: 1697.0 FT E(): 0, 34.1% identity in 953 aa overlap. Contains 2x FT PS00017 ATP /GTP-binding= match to entry PF00005 ABC_tran, FT ABC transporters, scores 42.40, E-value 1.7e-10 and 71.20, FT E-value 2.2e-17" FT /db_xref="GOA:O86699" FT /db_xref="InterPro:IPR003439" FT /db_xref="UniProtKB/TrEMBL:O86699" FT /protein_id="CAA20614.1" FT /translation="MSSAKRPGTPGPGSHVADSHDLIRVHGARENNLKDVSVDIPKRRL FT TVFTGVSGSGKSSLVFNTIAAESQRLINETYSAFVQGFMPTLARPEVDVLDGLTTAIIV FT DQQRMGADPRSTVGTATDVNAMLRILFSRLGEPRIGPPSAYSFNTASVRASGAITVERG FT NKKAVRATFERTGGMCTHCEGRGTVSDIDLTQLYDDSKSLAGGAFTIPGWKSDSQWTVQ FT VYAQSGFVDPDKPIREYTEKELRDFLYGEPVKVKVNGVNLTYEGLIPKIQKSFLSKDKE FT AMQPHIRAFVERAVTFTTCPECEGTRLSEGARSSKIKKISIADACAMEIRDLAEWVRDL FT TEPSVAPLLTALRDTLDSFVEIGLGYLSLDRPAGTLSGGEAQRVKMIRHLGSSLTDTTY FT VFDEPTVGLHPHDIQRMNDLLLRLRDKGNTVLVVEHKPEAIAIADHVVDLGPGAGTAGG FT TVCFEGTVEELRAADTVTGRHLDDRAVLKESVRKPAGALEIRDARTHNLQGVDVDVPLG FT VLCVVTGVAGSGKSSLIHGSVPAGADVVSVDQSPIKGSRRSNPATYTGLLDPIRKAFAK FT ANGVKPALFSANSEGACPTCNGAGVIYTDLAMMAGVATPCEDCEGKRFQPAVLEYRFGG FT RDISEVLAMSVDQAEEFFGAGEARTPAAHKILQRLSDVGLGYLTLGQPLTTLSGGERQR FT LKLATHMGEKGGVYVLDEPTTGLHLADVEQLLGLLDRLVDAGKSVIVIEHHQAVMAHAD FT WIIDLGPGAGHDGGRVVFEGTPADLVADRSTLTGEHLAAYVGA" FT misc_feature 36559..37788 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporters, score 42.40, E-value 1.7e-10" FT misc_feature 36580..36603 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 37981..38715 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporters, score 71.20, E-value 2.2e-17" FT misc_feature 38002..38025 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 38891..39373 FT /transl_table=11 FT /gene="SCO6518" FT /gene_synonym="SC5C7.03" FT /product="putative transcriptional regulator" FT /note="SC5C7.03, probable transcriptional regulator, len: FT 160 aa; similar in N-terminus to many e.g. RAMA_ENTCL FT transcriptional activator RamA (113 aa), fasta scores; opt: FT 175 z-score: 255.3 E(): 5.7e-07, 32.3% identity in 96 aa FT overlap. C-terminal 50 aa are unique. Contains Pfam match FT to entry PF00165 HTH_2, Bacterial regulatory FT helix-turn-helix proteins, araC family, score 71.40, FT E-value 1.9e-17" FT /db_xref="GOA:O86700" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:O86700" FT /protein_id="CAA20615.1" FT /translation="MTTLEDLARLRRARDLMDREYAEPLDVPALARVALMSAGHFSRSF FT RAAYGETPYSYLMTRRIERAMALLRRGDMSVTEVCFAVGCTSLGSFSSRFTELVGESPS FT AYRERDHADGAALPACVAKVYTRPVRNGEPGRSGTPAGKSESVRNGEAAPAPPPVA" FT misc_feature 38960..39220 FT /note="Pfam match to entry PF00165 HTH_2, Bacterial FT regulatory helix-turn-helix proteins, araC family, score FT 71.40, E-value 1.9e-17" FT CDS 39379..39795 FT /transl_table=11 FT /gene="SCO6519" FT /gene_synonym="SC5C7.04" FT /product="putative lyase" FT /note="SC5C7.04, possible lyase, similar to e.g. LGUL_HAEIN FT lactoylglutathione lyase (EC 4.4.1.5) (135 aa), fasta FT scores; opt: 124 z-score: 215.2 E(): 9.7e-05, 29.0% FT identity in 131 aa overlap" FT /db_xref="GOA:O86701" FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/TrEMBL:O86701" FT /protein_id="CAA20616.1" FT /translation="MDISLSQCFIAVDDHDRALAFYRDVLGLEVRNDVGYEGMRWVTLG FT SPAQPDVDIVLEPPLADPNASAADKQAMADLLAKGHLRGIILATDDVDATFEHVRAAGA FT EVLQEPVDQPYGVRDCAFRDPAGNMVRLHRPRKG" FT RBS 40066..40069 FT /note="possible RBS upstream of SC5C7.05" FT CDS 40082..40882 FT /transl_table=11 FT /gene="SCO6520" FT /gene_synonym="SC5C7.05" FT /product="putative RNA polymerase sigma factor" FT /note="SC5C7.05, probable RNA polymerase sigma factor, len: FT 266 aa; simlar to S. coelicolor sigma factors of the SigB FT subfamily e.g. TR:O52313 (EMBL:AF036131) putative RNA FT polymerase secondary sigma factor SigG (263 aa), fasta FT scores; opt: 1258 z-score: 1540.5 E(): 0, 72.9% identity in FT 251 aa overlap, and to RPOF_STRAU RNA polymerase sigma-F FT factor (297 aa), fasta scores; opt: 713 z-score: 858.3 E(): FT 0, 42.6% identity in 312 aa overlap. Possible alternative FT start 216 bp upstream, not supported by FramePlot. Contains FT helix-turn-helix motif at aa 228-249 (Score 2104, +6.35 SD) FT and Pfam match to entry PF00140 sigma70, Sigma-70 factors, FT score 210.40, E-value 2.8e-59" FT /db_xref="GOA:O86702" FT /db_xref="HSSP:1L0O" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:O86702" FT /protein_id="CAA20617.1" FT /translation="MPIHASVKHPHDDAPDTADAFRRLATLPDGPEHDELRDRIVEAWL FT PMAERLAGRFRSRGESFEDLRQVAALGLVKAVDRYDPERGNAFESYAVPTITGEIKRHF FT RDHMWTLHVPRRVQELRNRVRFAGQDLSQTIPGRRPTVAEIAERAELSEEDVRVGLEAL FT ESFTALSLDAELPGSEDGYSLGDALGAPDPALDTVVDREAVKDRLAALPPRERAILYMR FT FFNDMTQSRIAEQLGISQMHVSRLITRCCDRVREQVLRDPGPQA" FT misc_feature 40181..40849 FT /note="Pfam match to entry PF00140 sigma70, Sigma-70 FT factors, score 210.40, E-value 2.8e-59" FT RBS 41008..41013 FT /note="possible RBS upstream of SC3C7.06" FT CDS 41022..41978 FT /transl_table=11 FT /gene="SCO6521" FT /gene_synonym="SC5C7.06" FT /product="putative secreted protein" FT /note="SC5C7.06, probable secreted protein, len: 318 aa; FT contains N-terminal signal sequence" FT /db_xref="UniProtKB/TrEMBL:O86703" FT /protein_id="CAA20618.1" FT /translation="MRRTARALSVAVLASAALGLSAGVGAADPGVPPPPSGAGEPVVPP FT PADDSAAVPPPSAEEAPPPSAGQAAARVSPSDAGPGDTVTVSVSCGPTGGSAPASLDAT FT SAAFEEGTVALRKVADDAGTASGPAYRGTARIAAAEDFAAERPPADTTDPGGATDPEGA FT ANPEGATAPGSATDPGGVATDGEPSAGTEGWAETGDSAEAGDDWTVDGACPDASGGEGG FT DPWSATMSVPEESGAGAGAGAAQPACRESAAPRTGTSAHGTPCGGATAEHGVRAGAGGT FT FGDSVPALVAGGVLIAGACGAAAHRLRLRLRGEDGER" FT CDS 42047..43489 FT /transl_table=11 FT /gene="SCO6522" FT /gene_synonym="SC5C7.07" FT /product="hypothetical protein SC5C7.07" FT /note="SC5C7.07, unknown, len: 480 aa" FT /db_xref="GOA:O86704" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:O86704" FT /protein_id="CAA20619.1" FT /translation="MGTGINERRAKHRTDGNGPDGTRARHGQAARHGQAARTARRYGMR FT RTDPEGLATKPAGHDPAGRHGAGPGAVGHGPVRYGPHFPDDGLPVLPELSAVLAAAAGR FT ARGEPAGGAPALLEAASGYWDRRGLTTDPGHLAAAPGAGALLLALTAALGGDVLVPRPC FT AAWWAPYARLLGRPVFHVPTPAESGGVPDPYALLETVRRVRAEGGDPRLLVLSVADDPT FT GTVAPPELLHETVEAATGEGLHLVSDETWRDTLHDPHATVLLSPAEMLPERVTVVTDLA FT GALLPPAWPAAVARFPASAAGNGLHARVLDVLTALGARVAAPVAAAAGYALGEPEPVTA FT RRAAAVRLHARVAAAAHAAVVASGATARPPQAGRHLYADLGPLREALGAEGVGDAQELE FT DFLTARLGLPAPGGHRFGDDLPALRVRLATGPLLDAGTDERRAECLLSPDPLELPHVQR FT ALTGLKSVFDGLRDAQRWEPPR" FT RBS 43474..43477 FT /note="possible RBS upstream of SC5C7.08" FT CDS 43486..44526 FT /transl_table=11 FT /gene="SCO6523" FT /gene_synonym="SC5C7.08" FT /product="conserved hypothetical protein SC5C7.08" FT /note="SC5C7.08, unknown, len: 346 aa; similar to FT hypothetical proteins from M. tuberculosis YZ34_MYCTU FT MTCY31.34 (372 aa), fasta scores; opt: 678 z-score: 492.0 FT E(): 3.7e-20, 42.3% identity in 298 aa overlap, and to FT Saccharomyces cerevisiae TR:Q02883 (EMBL:U43281) LPG6P (468 FT aa), fasta scores; opt: 491 z-score: 495.9 E(): 2.2e-20, FT 35.5% identity in 262 aa overlap" FT /db_xref="UniProtKB/TrEMBL:O86705" FT /protein_id="CAA20620.1" FT /translation="MTQQPRSTARTPASAEDPAAAAAHPPLAAPRPPAEHRVWPRTFHD FT RLTAPLPGLKAFARFAREGAVRPGPAGLADVPRLPCAPGPLPRVDARTVAVTWAGHASW FT VVRIGGLTVLTDPVWSRRILGTPPRVTPVGVPWSALPRVDAVVISHNHYDHLDAPTLRR FT LPRDTPVLVPAGLGRWFHRRRFTHVTELDWWEATELNGVRFDFVPAHHWSKRSLTDTCR FT TLWGGWVLTDPDGRRVYFAGDTGYGHWFTRIGRRYPGIDLALLPIGAYDPRWWLSDVHC FT DPEEAVRAAQDVGARRMAPMHWGTFVLSAEPVLEPLARVRAAWQQAGLPRERLWDLPIG FT ASRVLE" FT CDS complement(44569..45195) FT /transl_table=11 FT /gene="SCO6524" FT /gene_synonym="SC5C7.09c" FT /product="putative integral membrane protein" FT /note="SC5C7.09c, probable integral membrane protein, len: FT 208 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:O86706" FT /protein_id="CAA20621.1" FT /translation="MSWLAAATLDIPTEPTQQALGYPSLFLLVLIGALVPVVPTGALVS FT SAAVVAMHQTVPFAMLMVFATASLAAFCGDMALYWLGRRGVGSKNGSRWLEAIRSRAPE FT DRLEQAQDKLAEHDVAVLVLSRLVPAGRIPVMLACLLAEWPLRRFARGNLPACLAWAVT FT YQLIGVLSGALFSKPWEGVAAAIALTVLVSVAPGVWRRLRGPAKA" FT CDS complement(45192..45959) FT /transl_table=11 FT /gene="SCO6525" FT /gene_synonym="SC5C7.10c" FT /product="conserved hypothetical protein SC5C7.10c" FT /note="SC5C7.10c, unknown, len: 255 aa; similar to FT hypothetical proteins from many organisms e.g. M. FT tuberculosis YZ34_MYCTU MTCY31.34 (372 aa), fasta scores; FT opt: 221 z-score: 293.2 E(): 4.4e-09, 30.7% identity in 251 FT aa overlap" FT /db_xref="UniProtKB/TrEMBL:O86707" FT /protein_id="CAA20622.1" FT /translation="MELTWWGHATCTVEDSGIRVLTDPLFVRRLAHLRRRRGAVPPPEA FT WRADVALVSHLHADHLHVPSLARLAPGTRLLVPRGARRAVPGLRRLGHLELTEVVPGDE FT TTVGDLRIRAVPARHDGRRLPVGRHRAPALGYVVEGEARTYFAGDTGLFDGMEQEVGPV FT DAALLPVGGWGPYLGAEHLDAGRAAEALARLAPRTAVPVHYGTYWPIGMDAVRPHEFHT FT PGEEFVRLSALRAPGVAVHRLGHGESVRVEVAR" FT RBS complement(45202..45207) FT /note="possible RBS upstream of SC5C7.09c" FT RBS complement(45966..45970) FT /note="possible RBS upstream of SC5C7.10c" FT RBS 46047..46050 FT /note="possible RBS upstream of SC5C7.11" FT CDS 46060..46461 FT /transl_table=11 FT /gene="SCO6526" FT /gene_synonym="SC5C7.11" FT /product="hypothetical protein SC5C7.11" FT /note="SC5C7.11, unknown, len: 133 aa" FT /db_xref="UniProtKB/TrEMBL:O86708" FT /protein_id="CAA20623.1" FT /translation="MGPVRVTAIASLTPLEQLDDDPFLVDSRSQHAMCARWAAEHGYVV FT ARQLLVRGLRPDHDALWDGVRPGHDLFVAPSRRVLESALSSVDAFSAECARRGVRVETV FT GQAEPSYDARMKACVHRRLSMPTAGYDGR" FT RBS 46564..46567 FT /note="possible RBS upsteam of SC5C7.12" FT CDS 46569..48722 FT /transl_table=11 FT /gene="SCO6527" FT /gene_synonym="SC5C7.12" FT /product="putative membrane protein" FT /note="SC5C7.12, probable membrane protein, len: 717 aa; FT contains large hydrophobic domain at N-terminus" FT /db_xref="GOA:O86709" FT /db_xref="UniProtKB/TrEMBL:O86709" FT /protein_id="CAA20624.1" FT /translation="MRSVGAGRWRRVASQVGRSVTVWAVSTLTMLVLAGILPDFRLQSP FT DGDSATDIAMTAAVGAGAFGLLSALVWPLMVRLLLLVPALVLGLLVFFLNGGLLLLAID FT VNPAGRGGVAPETAVVVAAVMSAVASATGGALAVRDDDAYRRRLYRLADRRRRSGPPCP FT ADPGTVFLQLDGVGHDVLLDAVDRGAMPTVARWLGRDGASATHRLAQWRTDWSSQTGAS FT QLGILHGSNHDVPAFRWYEKDSGEVMVCNRPTSAAELQYRAVRRTGDGGLLSLDGASRG FT NLFGGGADEQALVLSIATRRRSRETRSRSGYFAYFSDPANAVRTAMSFVAEVCREIGQS FT TRARVHKVRPRVSRGGLYPFVRAFATVVERDVVVAAVMGDMLAGRTAVYADLVAYDEVA FT HHSGPGGRDAAKVLGRLDRALALIENVAEHAPRPYRIVVLSDHGQSPGETFRARYGLTL FT ADLVRAGCGLPVPRSARRTRSGAEARNTVRAALHRPVEEGAEQQRPADTPTGRRSEPIV FT LASGNLGLVSFPDVPHRMTREEIDARHPALLATLANHPGIGFLLVRSEEHGGVVLGARG FT AEVPLDRLDQDPGPLAPFGPGAADAVRRTHTFPHTADIMVNSFHDPVDGEVLAFEEQIG FT SHGGLGGAQSRAFLLSPVVLSTPVDEGAEIVGAEHVHRVLRRWLRESNGPQVPVDPVDD FT SRSNAAEGAPFPVVDGYVQDKSA" FT RBS 48789..48792 FT /note="possible RBS upstream of SC5C7.13" FT CDS 48804..50228 FT /transl_table=11 FT /gene="SCO6528" FT /gene_synonym="SC5C7.13" FT /product="putative integral membrane transport protein" FT /note="SC5C7.13, probable integral membrane transport FT protein, len: 474 aa; similar to many e.g. ARCD_PSEAE FT arginine/ornithine antiporter (482 aa), fasta scores; opt: FT 560 z-score: 470.6 E(): 5.8e-19, 28.9% identity in 439 aa FT overlap" FT /db_xref="GOA:O86710" FT /db_xref="InterPro:IPR004841" FT /db_xref="UniProtKB/TrEMBL:O86710" FT /protein_id="CAA20625.1" FT /translation="MHVTGTVPPPAPEPRETPAAPDHTTLADPAPGNGRHARRFGLPVA FT TALVMGNIIGGGIFLLPASVAPFGTISLLAFGVLTVGAIALALVFGRLAARDPHTGGPY FT VYARGAFGDFAGFLAAWAYWITTWVSNAALAVAAVGYLDVLIPVNDHRWTACLAALVVQ FT WLPALANFAGTRWVGAVQLVSTVLKFAPLLLVAVGGLFFFDADNLGPFNASGSGGIGAV FT SAAAAILLFSYLGVESAAVSAGEVEDPRRTVGRATVIGTAGAALVYLLGTLSVFGTVAH FT DRLVTSDAPFSDAVNAMFGGAWGGWAVALAALVSMTGCLNGWTLLSAQTPYAAARDGLF FT PAAFARKRRGVPTTGVGVTVVLASLLTVYNYTSGSAKVFEVLVLVTTFTATVPYLLATA FT AQIFHLVSGQGERVDRARLVRDGIAASVAAAFSLWLVAGAGYAAVYQGVLFLFAGVLVY FT AVMAARRRRAETSNAP" FT RBS 50297..50301 FT /note="possible RBS upstream of SC5C7.14" FT CDS 50309..51370 FT /transl_table=11 FT /gene="SCO6529" FT /gene_synonym="SC5C7.14" FT /product="putative ATP/GTP binding protein" FT /note="SC5C7.14, probable ATP/GTP binding protein, len: 353 FT aa; similar to TR:Q9RV59 (EMBL:AE001966) Deinococcus FT radiodurans conserved hypothetical protein DR1171, 340 aa; FT fasta scores: opt: 453 Z-score: 502.2 E(): 2.4e-20; FT 33.692% identity in 279 aa overlap. Contains Prosite match FT to entry PS00017 ATP/GTP-binding" FT /db_xref="GOA:O86711" FT /db_xref="InterPro:IPR011704" FT /db_xref="UniProtKB/TrEMBL:O86711" FT /protein_id="CAA20626.1" FT /translation="MQAAVTVTPARLPELLLGLATVRPVFLWGAPGIGKSSLVRNFADS FT LGLECVSLLGTQLAPEDLIGVPQIRDGRSVFCPPESIARDEPYCLFLDELNAATPDVQK FT AFYSLILDRRIGNYELPKGSLVIGAGNRATDNALARPIASALVNRLTHVHLDASAKDWL FT VWAGENGIHPWITDHLTDRPDHLWSKPPKTEEPFSTPRSWHMLSDALHSFGQDLDEETL FT KVLAHGTLTPAHATAFCGYVKIVRSRFGIEAILKGEARWPSRIEDRDLLYYLAESFRGR FT LVKELPASKEHMSANGRQTAYRAKSLLVQLAEISVEVAQSVIASDADGNPLLPAWFLVE FT AARDMPRLVEARR" FT misc_feature 50393..50416 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 51355..51359 FT /note="possible RBS upstream of SC5C7.15" FT CDS 51367..53199 FT /transl_table=11 FT /gene="SCO6530" FT /gene_synonym="SC5C7.15" FT /product="hypothetical protein SC5C7.15" FT /note="SC5C7.15, unknown, len: 610 aa; contains Gln- and FT Lys-rich N-terminus" FT /db_xref="InterPro:IPR018698" FT /db_xref="UniProtKB/TrEMBL:O86712" FT /protein_id="CAA20627.1" FT /translation="MSPTRRQKQQQKQQQQQKQKKKDPAAEDCAKGVQLVWANPALAAM FT EVKLCREEECEVAPRHGLARVSSNGRVHLNPTRHAEPADWAWAIAHALIHLGFGHVPAA FT TGERVQPDRYDLAARCTVVNRFLLTFPVGRTPDHLPPTYPDGDEERIAAAWRREGGIPA FT AYEHCGTAGGEPDQLLSPWDGWNLQVPDWQLAFAHALTRTMSTALDLAGGRRDAMLGGP FT TRLQPWQRALSWFVSSYPLLGGIASGITLVADAELARAHGISVAAVNAEAGEIYVNPLR FT RYDDEEWRFILAHEMLHAALRHGDRCGTRDPYLFNVACDYVINGWLVEMQVGTMPEGLL FT HDPELAGLSAEEVYDRIAGDLRRIRRLSTPRGKGVGDVLGGPLRPPRDHVDLDGFYRRG FT LTQGLDLHQQQERGFLPAGLVEEIRVLSHPPLPWDARLARWFDEYVPRPEPVRSYARPS FT RRQAATPGIPRAGRYFPPEEIARCTFGVVLDTSGSMDRTLLGKALGAVASYAEARDVPA FT ARVVFCDAAPHDAGYLPVTDIAGRVRVHGRGGTVLQPGVDLLLRAEDFPPTAPVLVVTD FT GWCDVLRVRREHAYLIPQGARLPFTARGPVFRVS" FT RBS 53276..53279 FT /note="possible RBS upstream of SC5C7.16" FT CDS 53286..53711 FT /transl_table=11 FT /gene="SCO6531" FT /gene_synonym="SC5C7.16" FT /product="putative ATP/GTP binding protein" FT /note="SC5C7.16, probable ATP/GTP binding protein, len: 141 FT aa; highly similar to OSMC_ECOLI osmotically inducible FT protein C (143 aa), fasta scores; opt: 330 z-score: 398.2 FT E(): 6.2e-15, 44.5% identity in 137 aa overlap. Contains FT PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:O86713" FT /db_xref="HSSP:1QWI" FT /db_xref="InterPro:IPR019904" FT /db_xref="UniProtKB/TrEMBL:O86713" FT /protein_id="CAA20628.1" FT /translation="MATTRSAHTVWEGNLLEGNGVVTFDSSGIGEQPVSWPSRAEQANG FT KTSPEELIAAAHSSCFSMALSHGLAGAGTPPTKLTTSADVTFQPGEGIKGIHLTVEGTV FT PGLDNDAFVAAAEDAKKNCPVSQALTGTTITLSAKLA" FT misc_feature 53403..53426 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(53740..54462) FT /transl_table=11 FT /gene="SCO6532" FT /gene_synonym="narI" FT /product="putative nitrate reductase gamma chain NarI" FT /note="SC5C7.17c, narI, probable nitrate reductase gamma FT chain; len: 240 aa; similar to many e.g. NARI_BACSU nitrate FT reductase gamma chain (EC 1.7.99.4) (223 aa), fasta scores; FT opt: 664 z-score: 1084.3 E(): 0, 41.5% identity in 217 aa FT overlap. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="GOA:O86714" FT /db_xref="HSSP:1Q16" FT /db_xref="InterPro:IPR003816" FT /db_xref="UniProtKB/TrEMBL:O86714" FT /protein_id="CAA20629.1" FT /translation="MNVFLWGVLPYAAFALLIAGLVWRHRYDRFGWTTRSSQIYESKLL FT NIASPVFHYGILFVLAGHLIGLFIPASWTQSIGISEHAYHLFSLYGGTVSGVLAVAGIG FT MLVYRRRTNAPVFRATTANDKLMYVFLLGALLLGMIAKLSDTSGNGYDYRSTIAPWSRS FT LFTLNPKTELMAGVPVLYHVHAVVGMVLIALVPYTRLVHMFSAPLQYLTRPYVVYRSRD FT PRQLGPRPDRRGWERAGS" FT CDS complement(54459..54953) FT /transl_table=11 FT /gene="SCO6533" FT /gene_synonym="narJ" FT /product="putative nitrate reductase delta chain NarJ" FT /note="SC5C7.18c, narJ, probable nitrate reductase delta FT chain, len: 164 aa; similar to many e.g. NARJ_BACSU nitrate FT reductase delta chain (EC 1.7.99.4) (184 aa), fasta scores; FT opt: 208 z-score: 429.0 E(): 1.2e-16, 30.1% identity in 163 FT aa overlap" FT /db_xref="GOA:O86715" FT /db_xref="InterPro:IPR003765" FT /db_xref="UniProtKB/TrEMBL:O86715" FT /protein_id="CAA20630.1" FT /translation="MPGFEVLYQAAALCLTYPDDDFRARLPLLREAAPQLRGFTDHAAA FT TGQGELQAHYVEVFDFRNRHSLYLSWWTDGDTRNRGMSLVRFKELYRAHGLEFTGEELP FT DFLPAVLEFVSRTGDMGMLTEHRDALDQLRARLTAFGTPYACVLDAVCATLPPAPTGAR FT R" FT RBS complement(54470..54473) FT /note="possible RBS upstream of narI" FT CDS complement(54958..56553) FT /transl_table=11 FT /gene="SCO6534" FT /gene_synonym="narH" FT /product="putative nitrate reductase beta chain NarH" FT /note="SC5C7.19c, narH, probable nitrate reductase beta FT chain, len: 531 aa; highly similar to many e.g. NARH_BACSU FT nitrate reductase beta chain (EC 1.7.99.4) (487 aa), fasta FT scores; opt: 2099 z-score: 2179.2 E(): 0, 58.0% identity in FT 495 aa overlap. Contains PS00190 Cytochrome c family FT heme-binding site signature and Pfam match to entry PF00037 FT fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster FT binding domains, score 61.10, E-value 1.8e-16" FT /db_xref="GOA:O86716" FT /db_xref="HSSP:1R27" FT /db_xref="InterPro:IPR017896" FT /db_xref="UniProtKB/TrEMBL:O86716" FT /protein_id="CAA20631.1" FT /translation="MRPMAQVAMVMNLDKCIGCHTCSVTCKQAWTNRRGMEYVWFNNVE FT TRPGQGYPRRYEDQDKWRGGWELNRRGALKLKAGGRFKKLAGIFSNPRLPEIKDYYEPW FT TYDYKNLTDAPLGTDYPVARPVSQLDGKPMKIGWSSNWDDSLGGAPAYGDLDPMVERTR FT QQASEKVRFAYEETFMFYLPRICEHCLNPSCVASCPSGAMYKRSEDGIVLVDQDRCRGW FT RMCVTGCPYKKVYFNHRTGKAEKCTFCYPRIEVGQPTVCSETCVGRLRYLGVVLYDADK FT VTAAAETPNERDLYEAQLDVFLDPEDPGVRRAAEEAGIPFDWIEAARRSPVHALVSKYR FT VALPLHPEYRTMPMVWYIPPLSPVVDALTETGHDGEDADNLFGAIDTLRIPLEYLAELF FT TAGDTGPVRASLEKLAAMRAHMRSVNLGEDPDPAVCAGVGMRPEEIQEMYRLLAIAKYE FT ERYVIPTAAVGDAHRLEASALPDTCSLDTEGGPGMGGDGPFGQDSGRKRLPLVPVENFH FT ILRRRQTADDEREV" FT RBS complement(54962..54967) FT /note="possible RBS upstream of narJ" FT misc_feature complement(55843..56019) FT /note="Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins FT and related iron-sulfur cluster binding domains., score FT 61.10, E-value 1.8e-16" FT misc_feature complement(56491..56508) FT /note="PS00190 Cytochrome c family heme-binding site FT signature" FT CDS complement(56553..60248) FT /transl_table=11 FT /gene="SCO6535" FT /gene_synonym="narG" FT /product="putative nitrate reductase alpha chain NarG" FT /note="SC5C7.20c, narG, probable nitrate reductase alpha FT chain, len: 1231 aa; highly similar to many e.g. NARG_BACSU FT nitrate reductase alpha chain (EC 1.7.99.4) (1228 aa), FT fasta scores; opt: 4306 z-score: 3216.7 E(): 0, 51.5% FT identity in 1235 aa overlap. Contains PS00551 and PS00490 FT Prokaryotic molybdopterin oxidoreductases signatures 1 and FT 2 and Pfam match to entry PF00384 molybdopterin, FT Prokaryotic molybdopterin oxidoreductases, score 79.90, FT E-value 1e-24" FT /db_xref="GOA:O86717" FT /db_xref="HSSP:1R27" FT /db_xref="InterPro:IPR006468" FT /db_xref="UniProtKB/TrEMBL:O86717" FT /protein_id="CAA20632.1" FT /translation="MTDTRTPPTEPGAALLRAGRFFRPGTAAPDLHSVGLVGGRESDAF FT YRDRWSHDKVVTSTHGVNCTGSCRWNVFVKDGIITWETQATDYPSVGPDRPEYEPRGCP FT RGAAFSWYTYSPTRVRYPYVRGVLLEMYREAKARLTDPVLAWADIQGDPQRRQRYQRAR FT GKGGLVRASWDEAVEMVAAAHVHTIRTHGPDRIAGFSPIPAMSMVSHAAGARFHSLIGA FT PMLSFYDWYADLPVASPQVFGDQTDVPESGDWWDAAYLIMWGTNVPVTRTPDAHWMAEA FT RYRGQKVVVVSPDYADNTKFADQWLHPHPGTDAALAMAMGHVVLKEFFVDRVTPFFDDY FT VRRFTDLPFLVTLTERDGAYVPDKFLRAADLGQGGDDAYWKTVVLDEATGRAVVPNGSL FT GFRWNEADQGKWNLDLGDVRPRLSLHGHEMASGVEVLLPRFDTEGGTHGQGRGDVLRRG FT VPATRLGGATGPLVTTVFDLMLAQYGVTRPDLPGDWPASYEDADAPATPAWQETHTSVP FT AAACVRIAREFARTAERSKGRCMILMGAGTNHWFHSETIYRGFLALLQLTGCQGRNGGG FT WAHYVGQEKCRPVTGWASLAAASDWSRPPRQAIGTGYWYLHTDQWRYDRFRADVLASPL FT GEGRLAGMAGADCLALSARTGWMPSYPTFDRNPLELGETFGDPVANAVAELRAGTLRFA FT GEDPDAPENWPRIVTLWRANLLGSSGKGAEYFTKHLLGTQSSLRAEEAAPGERPRDVVW FT HEEAPEGKADLLLSLDFRHTSSTLLSDVVLPAATWYEKHDLSSTDMHPYVHAFSPAVNP FT PWQARTDFDTFKVLAEKLSELAEDHLGVRKDLVAAPLQHDTPGEIAQPGGVVRDWRRGE FT CEPEPGKTMPNLVVVERDYTAIGAKFAALGPLVETKGLPAKGITLKPDEEVARLRELNG FT AVRGGPADGRPALDTAVKAANTILALSGTTNGRLATQGFHTLEAKTGQEMAHLAAEHEG FT KRITYADTQAAPVPVITSPEWSGSEAGGRRYTAFTLNTEHLKPWHTLTGRQHFFVDHDW FT MHELGEALPVYRPPLDMHRLFGEPRLGPDGHREVTVRYLTPHNKWSIHSEYQDNLFMLA FT LSRGGQTIWMSAEDAAAIGVADDDWIEAVNRNGVVVARAIVSHRMPPGTVFMHHAQERT FT VNVPLTETTGKRGGVHNSLTRLLLKPTHLIGGYAQLSWAFNYLGPTGNQRDEVTVIRRR FT SQEVEY" FT RBS complement(56563..56569) FT /note="possible RBS upstream of narH" FT misc_feature complement(57768..57959) FT /note="Pfam match to entry PF00384 molybdopterin, FT Prokaryotic molybdopterin oxidoreductases, score 79.90, FT E-value 1e-24" FT misc_feature complement(57879..57932) FT /note="PS00490 Prokaryotic molybdopterin oxidoreductases FT signature 2" FT misc_feature 58128..58131 FT /note="end of true overlap with cosmid 1E6" FT misc_feature complement(60021..60077) FT /note="PS00551 Prokaryotic molybdopterin oxidoreductases FT signature 1" FT RBS complement(60254..60257) FT /note="possible RBS upstream of narG" FT CDS complement(60397..61212) FT /transl_table=11 FT /gene="SCO6536" FT /gene_synonym="SC5C7.21c" FT /product="conserved hypothetical protein SC5C7.21c" FT /note="SC5C7.21c, unknown, len: 271 aa; similar to two S. FT coelicolor hypothetical proteins SC1F2.04 (E(): 0, 51.3% FT identity in 269 aa overlap) and SC1F2.03c (E(): 4.5e-21, FT 44.7% identity in 275 aa overlap)" FT /db_xref="InterPro:IPR006764" FT /db_xref="UniProtKB/TrEMBL:O86718" FT /protein_id="CAA20633.1" FT /translation="MTGPEPASAPLDTSRPHPARVYDWWLGGKDNYPVDEELARRILAA FT DSTAVRGARANRRFMHRAVRTLAEAGIRQFLDIGTGIPTEPNLHQVAQAVAPESRVVYA FT DNDPIVLRHAEALLHGSAEGATEYVHADVRDPDRILRLAGESLDFDRPVALSLVALTHY FT LGDAADGDDVHGLLKRYKDVLAPGSHLVLSQVTPDLNPAAVGKAAELFARGGTPFHPRS FT LTEFARFFDGLELLGPGIIPVTGWRPDPEDVAAQTEGIVPVYAGVARKP" FT RBS complement(61223..61227) FT /note="possible RBS upstream of SC5C7.21c" FT CDS complement(61262..62125) FT /transl_table=11 FT /gene="SCO6537" FT /gene_synonym="SC5C7.22c" FT /product="conserved DNA-binding protein SC5C7.22c" FT /note="SC5C7.22c, unknown, len: 287 aa; similar to S. FT coelicolor hypothetical protein SC4G2.03 (E(): 2.2e-08, FT 29.2% identity in 257 aa overlap). Contains possible FT helix-turn-helix motif at aa 29-50 (Score 1251, +3.45 SD)" FT /db_xref="GOA:O86719" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:O86719" FT /protein_id="CAA20634.1" FT /translation="MSERRAAPTVGQVVLGRRLQELRETAGLKREEAAKVLRVAPATVR FT RMEMAEVSLKIPYVQILLTAYGVASDEVAAFVALAEEANQPGWWQRYHDVLPDWFSLYV FT SLEGAARIVRSYEPHFVPGLLQTEDYARSVLEAGTIGNAGADAVERHVSLRMERQRLLD FT RPDPPHLWVVMDETVLRRPVSIHGRVMREQLDKLLEFAARDRVTLQVAEFEDGPHPGTY FT APFTLFRFAEPELPDMVFTEYLTGALYLDSRTEVSAHLEVLDHMTARAASTQRTEKVLR FT EYRENF" FT RBS complement(62132..62136) FT /note="possible RBS upstream of SC5C7.22c" FT RBS 62339..62343 FT /note="possible RBS upstream of SC5C7.23" FT CDS 62354..62779 FT /transl_table=11 FT /gene="SCO6538" FT /gene_synonym="SC5C7.23" FT /product="putative integral membrane protein" FT /note="SC5C7.23, probable integral membrane protein, len: FT 141 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:O86720" FT /protein_id="CAA20635.1" FT /translation="MSTHQLAALARTAEPRLMLRRFLALDAAVTGANALAYLALSGPLG FT RCLGAGPGLLLALGAFLAVYAGCVGLLAARSRPPALAVRAVVEANLAWAAVSFAALALW FT LTPTTAGAVWTVLQALVVAAFALLQHGALRQDQGSSV" FT CDS complement(62761..63579) FT /transl_table=11 FT /gene="SCO6539" FT /gene_synonym="SC5C7.24c" FT /product="conserved hypothetical protein SC5C7.24c" FT /note="SC5C7.24c, hypothetical protein, len: 272 aa; FT similar to TR:Q985F1 (EMBL:AP003012) Rhizobium loti FT (Mesorhizobium loti) MLL7704 protein, 270 aa; fasta scores: FT opt: 786 Z-score: 877.1 E(): 3.2e-41; 48.638% identity in FT 257 aa overlap" FT /db_xref="GOA:O86721" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:O86721" FT /protein_id="CAA20636.1" FT /translation="MTALVSGTSPATDRGVGPMLRAWRERRRVSQLELALRADSSARHI FT SFVETGRSRPSEEMVLRLAEHLDVPVRERNALLLAAGYAPHYPETPLDDPALGALREGM FT ERLIRGYEPYPALVVDATYRVLAANRGIAMLMDGVAEHLLTPPLNAIRLTLHPDGLAPR FT IRNLREWRGHLLEQMERQIALHRSRPLRELYDEVAAYPVPESVPGAEPDEPVPYFALPM FT QIEHEGHVLSFISSISTFNTPMDVTVAELAIETLLPADPATVKYLQTLLP" FT RBS 63656..63660 FT /note="possible RBS upstream of SC5C7.25" FT CDS 63669..63974 FT /transl_table=11 FT /gene="SCO6540" FT /gene_synonym="SC5C7.25" FT /product="hypothetical protein SC5C7.25" FT /note="SC5C7.25, unknown, len: 101 aa; similar to several FT genes predicted to be pterin-4a-carbinolamine dehydratases FT e.g. Aquifex aeolicus TR:O66462 (EMBL:AE000671) phhB (99 FT aa), fasta scores; opt: 165 z-score: 280.7 E(): 2.2e-08, FT 30.3% identity in 89 aa overlap" FT /db_xref="GOA:O86722" FT /db_xref="HSSP:1F93" FT /db_xref="InterPro:IPR001533" FT /db_xref="UniProtKB/Swiss-Prot:O86722" FT /protein_id="CAA20637.1" FT /translation="MPAEPLSPQEVEERLATLPGWSLDAGRLTRSYRLGSHFAAAAMVV FT HVAQVQEELDHHSDLTLGYHTVALAVHTHSAGGAVTEKDVELARRVEDLAAGHGAH" FT CDS 63979..64725 FT /transl_table=11 FT /gene="SCO6541" FT /gene_synonym="SC5C7.26" FT /product="hypothetical protein SC5C7.26" FT /note="SC5C7.26, unknown, len: 248 aa; similar to FT hypothetical proteins and to TR:Q54529 (EMBL:U10405) FT Streptomyces purpurascens RdmD gene (required for FT modification on 10-position of aklavinone during FT anthracycline antibiotic synthesis) (237 aa), fasta scores; FT opt: 162 z-score: 217.3 E(): 7.4e-05, 36.1% identity in 158 FT aa overlap" FT /db_xref="GOA:O86723" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:O86723" FT /protein_id="CAA20638.1" FT /translation="MLDYDKEAERYDDSRGGEPRAAAAAEGVLSLVPRQARRLLDVACG FT TGIVTRRIVVGRDGLRVVGVDLAPAMARRAAARLPGAVVLADSRRLPFADGEFDAVASV FT WLLHLAGGAENVRAIVAECARVLRPGGTYVTTVDKGASHNVGSDIDAVLAARPAGVAHD FT AAHLVEAYAREYGLEPVGGARFTGHGQGRSPRRTVADLRRGWFVTLPPGEPLAEEFAAR FT LAVLPDQDRPRPDPVFTLAAFRKSPA" FT RBS 64782..64788 FT /note="possible RBS upstream of SC5C7.27" FT CDS 64796..66691 FT /transl_table=11 FT /gene="SCO6542" FT /gene_synonym="SC5C7.27" FT /product="putative secreted glycosyl hydrolase" FT /note="SC5C7.27, possible secreted glycosyl hydrolase len: FT 631 aa; similar to two hypothetical proteins from B. FT subtilis TR:O31526 (EMBL:Z99107) yesW (620 aa), fasta FT scores; opt: 2404 z-score: 2009.8 E(): 0, 57.7% identity in FT 620 aa overlap and TR:O31527 (EMBL:Z99107) yesX (612 aa), FT fasta scores; opt: 1856 z-score: 1984.4 E(): 0, 54.4% FT identity in 599 aa overlap. Contains possible N-terminal FT signal sequence. Similar to TR:Q9AF09 (EMBL:AY026755) FT rhamnogalacturonan lyase from Pseudomonas cellulosa (881 FT aa) fasta scores; opt: 2392, Z-score: 2482.1, 59.091% FT identity (61.043% ungapped) in 594 aa overlap." FT /db_xref="GOA:O86724" FT /db_xref="InterPro:IPR013517" FT /db_xref="UniProtKB/TrEMBL:O86724" FT /protein_id="CAA20639.1" FT /translation="MRHPHTRPHAPHPHRRRPRALAAALAAAGLLGAGLTTLAPDTAEA FT ATARQVEALDRGVVSVHTGDGNLVSWRWLGTDPDNVAFNVYRAGTKVNSSPVTGSTTYF FT HSGAPSHADYTVRAVVNGTEQGDSVHAIQFRAGYKDVPISPPSGGTTPDGVSYTYEAND FT ASVGDLDGDGALDLVLKWQPTNAKDNSQSGYTGNTVVDGIKLDGTRLWRVDLGRNIRSG FT AHYTQFQVYDYDGDGRAEVAMKTADGTKDGTGAVIGNSSADHRNSSGYVLSGPEYLTMF FT NGRTGTAMGTVDYVPARGSVSSWGDSYGNRVDRFLAGTAYLDGSRPSVIMARGYYTRTV FT IAAWDWRDGRFTRRWTFDTNSSTNSGKGYDGQGNHQLSVADVDGDGRDEIVYGAMAVDD FT NGYALWTTRNGHGDAMHVGDLDPSRAGLEEFKVDEDGSKPSSYLADARTGQILWSTGAS FT GDNGRGVSGDIWSGSAGAESWSSAESGIRNPKGTVVGSRKPSSANFLSWWDGDTVRELL FT DGTHVDKYGTSGDTRLLTGSGVASNNGTKATPVLAGDILGDWREEVVWRTSNNTALRIY FT STPYDTDTRITTLLHDTQYRTALAWQNTAYNQPPHPSFFLGSGMPTAPRPSVHTP" FT CDS complement(66695..66940) FT /transl_table=11 FT /gene="SCO6543" FT /gene_synonym="SC5C7.28c" FT /product="hypothetical protein SC5C7.28c" FT /note="SC5C7.28c, unknown, len: 81 aa" FT /db_xref="UniProtKB/TrEMBL:O86725" FT /protein_id="CAA20640.1" FT /translation="MARTWEGPAGRLLLGLAVLLHRTVTDRAAKRRLEHWRNAALRAAY FT RRGVPVGVLASRTRLTQRWVRTVVTGGKPPPVDEAA" FT RBS complement(66954..66957) FT /note="possible RBS upstream of SC5C7.28c" FT CDS 67214..67894 FT /transl_table=11 FT /gene="SCO6544" FT /gene_synonym="SC5C7.29" FT /product="putative membrane protein" FT /note="SC5C7.29, possible membrane protein, len: 226 aa; FT contains possible transmembrane domain around aa 40" FT /db_xref="UniProtKB/TrEMBL:O86726" FT /protein_id="CAA20641.1" FT /translation="MNTNFTPPPMPSYGPSPVPPPPPPRKNRTLLVAVAAAVVAAAVSA FT AVTAGVTGDDEAGPAPTVTVTETASVGGGDTPAAEEESAEEAPAASEDTDDGVHALDET FT VTYEPDVEVSLSGFERTVSSEYAMPEKTPYARFTVKVRNSGTKTLDTTLLTVNCSYGKE FT GRSSESVFDSDTGLDGTPQTKLLAGRSINVPWGCELPKGEKLIQIEVAPDFDSETAIFT FT GPVT" FT CDS complement(67887..70559) FT /transl_table=11 FT /gene="SCO6545" FT /gene_synonym="SC5C7.30c" FT /product="putative secreted cellulase" FT /note="SC5C7.30c, probable secreted cellulase, len: 890 aa; FT similar to TR:D1029971 (EMBL:AB015511) Aspergillus FT aculeatus avicelase III (856 aa), fasta scores; opt: 2099 FT z-score: 1414.5 E(): 0, 44.5% identity in 845 aa overlap, FT and to many others e.g. GUNA_MICBI endoglucanase A FT precursor (EC 3.2.1.4) (456 aa), fasta scores; opt: 416 FT z-score: 340.7 E(): 9.9e-12, 28.5% identity in 449 aa FT overlap (strongest in the cellulose-binding domain). FT Contains probable N-terminal signal sequence and Pfam match FT to entry PF00553 CBD_1, Cellulose binding domain, score FT 171.70, E-value 8.5e-49 at C-terminus" FT /db_xref="GOA:O86727" FT /db_xref="HSSP:1EXG" FT /db_xref="InterPro:IPR012291" FT /db_xref="UniProtKB/TrEMBL:O86727" FT /protein_id="CAA20642.1" FT /translation="MRRTRILTVLLALAAGLLAGSPPAASAAEPAPRAAVAADSYTWKN FT ARIDGGGFVPGIVFNRTEKDLAYARTDIGGAYRWQEESHTWTPLLDHVGWDDWGHTGVV FT ALASDAVDPDRVYAAVGTYTNDWDPTNGAVLRSADRGASWEKADLPFKLGGNMPGRGMG FT ERLAVDPHDNDVLYLGAPSGHGLWRSTDAGVTWSEVTAFPNPGNYAQDPNDTSGYASDN FT QGITWVTFDESTGGGAGTATRTLYVGVADKENAVYRSTDAGATWERLAGQPTGYLAHKG FT VLDAENGYLYLAYSDTGGPYDGGKGRLYRYATATGTWTDISPAAEADTYYGFSGLTVDR FT QRPGTVMATAYSSWWPDTQIFRSTDSGATWSQAWSYTSYPDRENRYTMDVSSSPWLTWG FT ANPAPPEQTPKLGWMTEALEIDPFDSDRMMYGTGATVYGTENLTNWDDEGGTFAVEPMV FT RGLEETAVNDLASPPSGAPLLSALGDVGGFRHTSLTEVPSMMYTSPNFTSTTSLDFAET FT KPDVVVRAGNLDSGPHIAFSTDNGANWFGGTDPSGVSGGGTVAAGADGSRFVWSPEGAG FT VQYTTGFGTSWQASTGLPAGAIVESDRVNPATFYGFKSGRFYVSTDGGATFTASAATGL FT PAGDGVRFKALPGGEGDVWLAGGAADGPYGLWHSTDGGGTFTRLPGVDAADTVGFGKAA FT PGASYQTLFTSAEIGGVRGIFRSTDAGATWTRVNDDAHQWGWTGAAITGDPRVYGRVYV FT ATNGRGVIYGDTSDTGGGTDPGPGPDPTPTGACEVTYTVTNQWPGGFQADVRLTNTGTS FT AWNGWSLDWSFPGGQEVTRMWNAEHTQAGTSVTARNVGWNAGVAPGASVGFGFTGSRSG FT TNAEPEGFAVAGRACPTAT" FT misc_feature complement(67902..68204) FT /note="Pfam match to entry PF00553 CBD_1, Cellulose binding FT domain, score 171.70, E-value 8.5e-49" FT misc_feature 70490..70493 FT /note="end of true overlap with cosmid 4B5" FT RBS complement(70572..70576) FT /note="possible RBS upstream of SC5C7.30c" FT CDS complement(70806..73727) FT /transl_table=11 FT /gene="SCO6546" FT /gene_synonym="SC5C7.31c" FT /product="putative secreted cellulase" FT /note="SC5C7.31c, probable secreted cellulase, len: 973 aa; FT N-terminus is similar to the cellulose binding domain of FT e.g. GUN4_THEFU endoglucanase E-4 precursor (880 aa), fasta FT scores; opt: 341 z-score: 352.0 E(): 2.3e-12, 43.7% FT identity in 103 aa overlap. C-terminus is similar to many FT cellulases e.g. GUXB_CELFI exoglucanase B precursor (1090 FT aa), fasta scores; opt: 2997 z-score: 2688.8 E(): 0, 61.4% FT identity in 699 aa overlap. Contains probable N-terminal FT signal sequence and Pfam match to entry PF00553 CBD_1, FT Cellulose binding domain, score 122.30, E-value 2.4e-34 FT near N-terminus" FT /db_xref="GOA:O86728" FT /db_xref="HSSP:1FAE" FT /db_xref="InterPro:IPR000556" FT /db_xref="UniProtKB/TrEMBL:O86728" FT /protein_id="CAA20643.1" FT /translation="MHSGHRPGRRTARRWWTAALAALALPLTMLGTGSTPAQAAALQCS FT VDYKTNDWGAGFTAELTLTNHGTDAIDGWTLTYSYAGNQKLTNGWNGTWSQSGPDVTVK FT NASYNARIAAGAAVSTGGQFTYSGSNAAPANFAVNGTSCVGAHQPPITVLTSPEAGAVY FT SRGEAVPLAATAAAADGATISKVEFYDDATLLGTDTSSPYTYSASGLTVGSHSLVAKAY FT DSMGASADSTPVGVTVAAGPTVVASPGQLGVQQGESGTYEVKLSEQPTANVTVTTSRAS FT GNTGLTLTGGASLTFTPSNWDTAQRVTVSADASGSGSAVFESTAPGHGKAAVTVTQLAA FT AKDYDARFLELYGKITDPANGYFSPEGIPYHSVETLIVEAPDHGHETTSEAYSYLLWLQ FT AMYGKVTGDWSKFNNAWEIMETYMIPTHADQPTNSSYNASKPATYAPELDTPNEYPAPL FT DGTVSVGSDPIAGELKSAYGTDDVYGMHWLQDVDNTYGYGNSPGKCEAGPSDTGPSYIN FT TFQRGAQESVWETVPQPTCDAFKYGGKNGYLDLFTGDASYAKQWKFTNAPDADARAVQA FT AYWADIWAGEQGKSDEISATLDKAAKMGDYLRYAMFDKYFKKVGNCVGPSACPAGTGKD FT SSHYLLSWYYAWGGAVDTSAGWAWRIGSSHTHGGYQNPLAAYALSTDADLKPKSATGQS FT DWAKSLDRQVEFYRWLQSDEGAIAGGATNSWAGRYATPPAGTPTFYGMYYDEKPVYHDP FT PSNQWFGFQAWSMERVAEYYQQSGDAGAKAVLDKWVDWALSETTVNPDGTFRIPSTLQW FT SGQPDTWNASSPGANGDLHVEVADYTNDVGVAAAYAKTLTYYADRSGDTEAASTAKALL FT DGMWENNQDALGIAVPETRADYNRFDDGIYVPSGWSGTMPNGDTVDASSTFASIRSFYQ FT DDPAWSKIESYLRGGAAPTFTYHRFWAQADIALAMGSYAELLE" FT misc_feature complement(73299..73598) FT /note="Pfam match to entry PF00553 CBD_1, Cellulose binding FT domain, score 122.30, E-value 2.4e-34" FT RBS complement(73738..73744) FT /note="possiblke RBS upstream of SC5C7.31c" FT CDS 74086..74250 FT /transl_table=11 FT /gene="SCO6547" FT /gene_synonym="SC5C7.32" FT /product="very hypothetical protein SC5C7.32" FT /note="SC5C7.32, questionable ORF, len: 54 aa" FT /db_xref="UniProtKB/TrEMBL:O86729" FT /protein_id="CAA20644.1" FT /translation="MPDRSPLGPFHRARGPFLTSDHDGTPMPIGSGPHRHGRGPGRQQH FT PHERRNPHS" FT RBS 74232..74236 FT /note="possible RBS upstream of SC5C7.33" FT CDS 74247..75986 FT /transl_table=11 FT /gene="SCO6548" FT /gene_synonym="SC5C7.33" FT /product="putative secreted cellulase" FT /note="SC5C7.33, probable secreted cellulase, len: 579 aa; FT similar to many, e.g. TR:Q60029 (EMBL:U18978) FT beta-1,4-exocellulase precursor (596 aa), fasta scores; FT opt: 2131 z-score: 2323.9 E(): 0, 62.1% identity in 585 aa FT overlap. Contains possible N-terminal signal sequence, FT PS00655 Glycosyl hydrolases family 6 signature 1 and Pfam FT match to entry PF00553 CBD_1, Cellulose binding domain, FT score 161.20, E-value 9.8e-46 near C-terminus" FT /db_xref="GOA:O86730" FT /db_xref="HSSP:1EXG" FT /db_xref="InterPro:IPR001524" FT /db_xref="UniProtKB/TrEMBL:O86730" FT /protein_id="CAA20645.1" FT /translation="MTRTRTAMLAALTLVAGASGTALAAHSASAGAAAAACTVDYQVQN FT DWGSGFTAAVTVTNNGAATSSWSLGWTYAGSQKVTNSWNAKVTQSGAAVTAANESYNGT FT LSTGGSASFGFQGTYSGSNAIPATFTLNGVTCNVDGGTDPTDPPTDPTDPPTDPTGPGD FT RVDNPYDGAQVYVNPEWSANAAAEPGGDRIADEPTGVWLDRIAAIEGANGGMGLRDHLD FT AALEQKGSGEMVVQLVIYNLPGRDCSALASNGELGPTEIDRYKTEYIDPIAEILSDSKY FT ADLRIVTTVEIDSLPNLVTNVSGRPTATENCDVMKANGNYQKGVGYALNRLGAVGNVYN FT YVDAGHHGWLGWDSNFGPSAEIFKTAATTEGATLDDVHGFIVNTANYSALKEENFKITD FT SVNGTSVRQSDWVDWNQYTDELSYAQAMRDKLVSLGFDQNLGMLIDTSRNGWGGADRPT FT GPGATTDVNTYVNGGRYDRRIHLGNWCNQSGAGLGERPQASPAAGIDAYVWMKPPGESD FT GSSKLIDNPDGKGFDRMCDPTYTGNERNGNSMSGALPDAPISGAWFSAQFQELMKNAYP FT PLS" FT misc_feature 74355..74654 FT /note="Pfam match to entry PF00553 CBD_1, Cellulose binding FT domain, score 161.20, E-value 9.8e-46" FT misc_feature 74958..75008 FT /note="PS00655 Glycosyl hydrolases family 6 signature 1" FT RBS 76133..76137 FT /note="possible RBS upstream of SC5C7.34" FT CDS 76146..77090 FT /transl_table=11 FT /gene="SCO6549" FT /gene_synonym="SC5C7.34" FT /product="hypothetical protein SC5C7.34" FT /note="SC5C7.34, unknow, len: 314 aa; highly His-rich in FT N-terminus" FT /db_xref="InterPro:IPR013217" FT /db_xref="UniProtKB/TrEMBL:O86731" FT /protein_id="CAA20646.1" FT /translation="MAHDHHHDTHGPAHQQGHGHGQGHGHGHGHTHDHADIDWAEMAPH FT LEAQAELYTPLYRQALTWLAGEVTEPGLVVDVGSGPGVVSCLFADTFPGARVVAADGAA FT PLLERARARAERLGFGDRFGTLAGDLPGALAELDYPADLMWASQSLHHLPDQRAALAAL FT GGHLAPGGTLAILEGGLPARFLPRDIGTGRPGLQARIRAVEEDAFAEMRADLPDSVAEA FT EDWPAMLTAAGLKHTGTRSFLLDLPAPLSDAGRDYVTTSLSRLRERIGERLDAEDRATL FT DRLLDPADEAGVHRRQDLFVLVAHTVYTAVRPV" FT RBS 77165..77170 FT /note="possible RBS upstream of SC5C7.35" FT CDS 77175..77876 FT /transl_table=11 FT /gene="SCO6550" FT /gene_synonym="SC5C7.35" FT /product="putative oxidoreductase" FT /note="SC5C7.35, probable oxidoreductase, len: 233 aa; FT similar to many e.g. TR:O54197 (EMBL:AJ000671) Streptomyces FT clavuligerus clavulanate-9-aldehyde reducatase (247 aa), FT fasta scores; opt: 340 z-score: 414.7 E(): 7.5e-16, 34.0% FT identity in 238 aa overlap. Contains Pfam match to entry FT PF00106 adh_short, Alcohol /other dehydrogenases, short FT chain type, score 129.10, E-value 8e-35" FT /db_xref="GOA:O86732" FT /db_xref="HSSP:1BDB" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:O86732" FT /protein_id="CAA20647.1" FT /translation="MTDAPVTLITGGGSGIGAAVARRLLDAGQRVAVTGRGEERLRAFS FT AELGDPAGLLTLRGSAAEHTQVVSAVEATLKEFGRIDTVVANAGFATHDSVAEGDPAGW FT TEMVLTNVLGPALLIRASIDALKATRGRIVLVGSVAGFVNTPGNIYGATKWAVTGLAEN FT TRREVTQWGVGVTLIAPGRVETPFWDGTGGLPPGELLTAGQIADSVVWAMTQPAGVDVN FT TVVVRPLGQPN" FT misc_feature 77187..77732 FT /note="Pfam match to entry PF00106 adh_short, Alcohol FT /other dehydrogenases, short chain type, score 129.10, FT E-value 8e-35" FT stem_loop 77878..77925 FT /note="hairpin loop with 23 bp stem" FT misc_feature 77882..77993 FT /note="Overlap with Streptomyces coelicolor cosmid 5C7 FT (EMBL:AL031515)." FT CDS complement(77934..78767) FT /transl_table=11 FT /gene="SCO6551" FT /gene_synonym="SC4B5.01c" FT /product="putative oxidoreductase" FT /note="SC4B5.01c, probable oxidoreductase, len; 277aa, FT similar to many eg. TR:P06632 (EMBL:M12799) FT 2,5-diketo-D-gluconic acid (2,5-DKG) reductase from FT Corynebacterium sp. (278 aa), fasta scores; opt: 938, FT z-score: 1372.7, E(): 0, (52.9% identity in 276 aa FT overlap). Contains PS00063 Aldo /keto reductase family FT putative active site signature, PS00062 Aldo /keto FT reductase family signature 2 and Pfam match to entry FT PF00248 aldo_ket_red, Aldo /keto reductase family, score FT 464.50, E-value 3.6e-136." FT /db_xref="GOA:Q9ZBW7" FT /db_xref="HSSP:1HW6" FT /db_xref="InterPro:IPR020471" FT /db_xref="UniProtKB/TrEMBL:Q9ZBW7" FT /protein_id="CAA22355.1" FT /translation="MSSKVPPIILNNGVEMPQLGFGVWQVPDDDAQTAVALALEAGYRS FT IDTAAIYGNEEGTGRAIAASGLAREDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYL FT DLYLIHWPMPAKERYVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQ FT IELHPHLQQHAAREVHAEQGIATEAWSPLGSGKGILDIPAIVAIAQKHGRTPAQVVLRW FT HLQLGNVVIPKSVTPSRIKENIDVFGFSLDTEDLAAISALNEDRRLGSDPADVNS" FT misc_feature complement(77967..78740) FT /note="Pfam match to entry PF00248 aldo_ket_red, Aldo /keto FT reductase family, score 464.50, E-value 3.6e-136" FT misc_feature complement(78030..78077) FT /note="PS00063 Aldo /keto reductase family putative active FT site signature." FT misc_feature complement(78339..78392) FT /note="PS00062 Aldo /keto reductase family signature 2." FT CDS complement(78851..80677) FT /transl_table=11 FT /gene="SCO6552" FT /gene_synonym="SC4B5.02c" FT /product="putative long-chain-fatty-acid-CoA ligase" FT /note="SC4B5.02c, probable long-chain-fatty-acid-CoA FT ligase, len: 608aa, similar to many eg. TR:O53521 FT (EMBL:AL021957) putative long-chain-fatty-acid-CoA ligase FT from Mycobacterium tuberculosis (600 aa), fasta scores; FT opt: 1177, z-score: 1838.1, E(): 0, (44.8% identity in 612 FT aa overlap). Contains Pfam match to entry PF00501 FT AMP-binding, AMP-binding enzyme, score -73.00, E-value FT 7.8e-11 and PS00455 Putative AMP-binding domain FT signature." FT /db_xref="GOA:Q9ZBW6" FT /db_xref="HSSP:1LCI" FT /db_xref="InterPro:IPR000873" FT /db_xref="UniProtKB/TrEMBL:Q9ZBW6" FT /protein_id="CAA22356.1" FT /translation="MREFTSPPLALAPPVGGLADVVFEHALDDPRHIALGRKDDAGQWR FT DVTAGAFRDEVLALAKGLLAQGIRFGDRVAIMSRTRYEWTLFDFALWTIGAQVVPIYPT FT SSAEQCMWMLYDAEVTAAVVEHEDHAMTIATVIDRLPHLRGLWQLDSGAVQELYDAGAH FT LDDEVVHRHRKAVTPESVATVIYTSGTTGRPKGCVLTHGSFMYEADTVIERWEPVFHSK FT RGDEAATLLFLPLAHVFGRMVEVAAIRGRVRFGHQPQLNAAALLPDLAAFRPTFILAVP FT YIFEKVFNAARRKAEKEGKAGPFEKAVDVAVKYAEAVEAKAWGDGPGPSAGLRMQHQFF FT DKLVYSKVRAAMGGRIRNAMSGGSAMDRRLGLFFAGAGVQIYEGYGLTESTAAATANPP FT ERTRYGTVGQPIPGTTVHIADDGEIWLNGDNVFEGYLNNPKATDETLHDGWLATGDLGA FT LDEDGYLTITGRKKEILVTSGGKSVSPGLLEERVRDHPLVNQCIVVGNDRPYVAALITL FT DQEAVEHWLTMRNKPRMSPADLVHDADLETEVRRAVVAANTLVSQAESIRTFRILAQPF FT TEEHGLLTPSLKLKRKAIENAYGTEVEALYTA" FT misc_feature complement(79169..80521) FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score -73.00, E-value 7.8e-11" FT misc_feature complement(80092..80127) FT /note="PS00455 Putative AMP-binding domain signature." FT CDS complement(80906..82420) FT /transl_table=11 FT /gene="SCO6553" FT /gene_synonym="SC4B5.03c" FT /product="putative integral membrane efflux protein" FT /note="SC4B5.03c, probable integral membrane efflux FT protein, len: 504aa; similar to a family of integral FT membrane transport proteins most of which appear to be FT concerned with export of antimicrobial compounds, most FT similar to SW:TCMA_STRGA tetracenomycin C resistance and FT export protein from Streptomyces glaucescens (538 aa), FT fasta scores; opt: 790, z-score: 800.0, E(): 0, (33.8% FT identity in 497 aa overlap). Contains PS00216 Sugar FT transport proteins signature 1. Also contains several FT putative membrane spanning regions." FT /db_xref="GOA:Q9ZBW5" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9ZBW5" FT /protein_id="CAA22357.1" FT /translation="MRTWGPLTAVCLGTFMLLLDVTIAVVALPDMARGLHASLSDLQWV FT MDGYALALAALLLGLGAAADVLGRRRVHVAGVVLFAVASLLCGLATGPGMLVAARGLQG FT LGAAAMFATTLPLLGSVYQGRRRSMALGVWGAVSGAAAAVGPVLGGLLTDGPGWRWIFW FT VNLPVSVAAVWLTLRVVPESRGAAGRRVDWAGTATFAAFAGAVTYGAVRAGSHGWTEGG FT TLVSFALAVVALGAFVAVEHRVADPLLDPRLFLRPAFSGVMLGGLAFNAAAFGVMAYTS FT IWLQTMLGMSPVRGGLVFVWLSLASFVVAAAGGRLLHGVPARLTIGGGLLLIAAGQFCM FT AFLDAGSTASALVPGLLLVGVGTGLVSPGIAGAALAAVPAERSGMAGGAVNTFRQLGYA FT LGIAVFGTVLTSRMQDRLPHDAAHGLAGGAAGALRGVFGEHALRASFASGLNAAAVAAG FT AVAAVAGVLVLVLVGAGRGGRNAGVTDSAPPALEEEEATPVAPYRR" FT misc_feature complement(82193..82243) FT /note="PS00216 Sugar transport proteins signature 1." FT CDS 82536..83519 FT /transl_table=11 FT /gene="SCO6554" FT /gene_synonym="SC4B5.04" FT /product="putative transcriptional regulatory protein" FT /note="SC4B5.04, probable transcriptional regulatory FT protein, len: 327 aa; C-terminal region weakly similar to FT several members of the asnC family of transcriptional FT regulators e.g. SW:Y723_METJA putative transcriptional FT regulatory protein from Methanococcus jannaschii (156 aa), FT fasta scores; opt: 167, z-score: 267.8, E(): 1.3e-07, FT (24.1% identity in 141 aa overlap). Contains probable FT helix-turn-helix motif (score 1226, +3.36 SD) from residue FT 198 to 219." FT /db_xref="GOA:Q9ZBW4" FT /db_xref="InterPro:IPR019888" FT /db_xref="UniProtKB/TrEMBL:Q9ZBW4" FT /protein_id="CAA22358.1" FT /translation="MEMESDAFDELDLGLLDALEVNGRASFSRIGAVLGVSDQTVARRY FT RRLCAEGGLRVVAVRDAERLGQDQWTLRLRCVPDSSAAIADALAKRPDTNWIGVASGGT FT EVILGTRPRSPGARDDLLLGKLPRTPRVLEIHAHQMLHRFYGGPSGWLRKFGVLSEEQV FT AALRNEPDPARRGPARIDPEDEPLLAVLERNGRATYPELQRATGRSESAVKRRLAALLA FT SGAVYIDVEYDPDILGYRTDAALWITTSPAALHRVGEALAAHDEIAHVAATAGPSNIIA FT TAVVRSTADLYTYLSGPLGHLEGVQHLEASPLLRRVKRLTYQRPVR" FT CDS complement(83501..84379) FT /transl_table=11 FT /gene="SCO6555" FT /gene_synonym="SC4B5.05c" FT /product="LysR-family transcriptional regulator" FT /note="SC4B5.05c, LysR-family transcriptional regulator, FT len: 295 aa; similar to several members of the LysR family FT of transcriptional regulators eg. TR:G3273739 FT (EMBL:AF057064) HexA from Erwinia carotovora subspecies FT atroseptica (316 aa), fasta scores; opt: 453, z-score: FT 562.2, E(): 5.1e-24, (32.6% identity in 276 aa overlap). FT Contains PS00044 Bacterial regulatory proteins, lysR family FT signature, PS00287 Cysteine proteases inhibitors signature FT and Pfam match to entry PF00126 HTH_1, Bacterial regulatory FT helix-turn-helix proteins, lysR family, score 143.70, FT E-value 3.3e-39. Contains strong helix-turn-helix motif FT (score 2054, +6.18 SD) at residue18 10 39." FT /db_xref="GOA:Q9ZBW3" FT /db_xref="InterPro:IPR018073" FT /db_xref="UniProtKB/TrEMBL:Q9ZBW3" FT /protein_id="CAA22359.1" FT /translation="MYDPSHLRTFLSVAQTLSFTQAARRLGLRQSTVSQHVRRLEDATG FT RQLFSRDTHSVELTEDGEAMLGFARRILEVHEQATAFFTGTRLRGRLRFGASEDFVLTR FT LPEILEAFRHDHPEVDLELTVELSGTLHEQLAAGKLDLVLAKRRPEDPRGEPVWSDRLV FT WIGAERLRLEPDRPVPLIVYPPPGITRALALDALQRQGRAWHIACTSGSLNGLIAAARA FT GLGVMAHSRGLVPPGLVRVPDRAGLPELGGVDFVLVHGGRRPSAQGAADALAAAILAGG FT DRLHRPQRTGL" FT misc_feature complement(83948..84370) FT /note="Pfam match to entry PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix proteins, lysR family, score FT 143.70, E-value 3.3e-39" FT misc_feature complement(84236..84328) FT /note="PS00044 Bacterial regulatory proteins, lysR family FT signature." FT CDS 84532..85569 FT /transl_table=11 FT /gene="SCO6556" FT /gene_synonym="SC4B5.06" FT /product="putative transmembrane protein" FT /note="SC4B5.06, possible transmembrane protein, similar to FT SW:YFEH_ECOLI Hypothetical protein from Escherichia coli, FT (332 aa), fasta scores; opt: 985, z-score: 1173.2, E(): 0, FT (48.9% identity in 323 aa overlap). Hydrophobic with FT several possible membrane spanning regions." FT /db_xref="GOA:Q9ZBW2" FT /db_xref="InterPro:IPR002657" FT /db_xref="UniProtKB/TrEMBL:Q9ZBW2" FT /protein_id="CAA22360.1" FT /translation="MKRLRWPRWMPIDPYILLLLGTVGLAALLPARGTGADVASGASTG FT AIAFLFFLYGARLSTREAMDGVRHWRLHVTVLACTFVVFPLLGLASRGLVPVFLTDPLY FT QGLLFLTLVPSTIQSSIAFTSIARGNVPAAICAGSFSSLVGIVVTPLLAAALLGGGGGG FT FSADSVVKIVLQLLVPFLAGQLLRRWIGGFVARHKKVLGLVDRGSILLVVYTAFSEGMV FT EGIWHQVSPARLAGLLAVQAVLLAVMLALTWYGAKGLGFGREDRIAIQFAGSKKSLAAG FT LPMASVLFGAQASLAVLPLMLFHQMQLMVCAVIAKRRSRDPEAVASEESAARVRTAVGT FT GSRSG" FT CDS complement(85596..87542) FT /transl_table=11 FT /gene="SCO6557" FT /gene_synonym="SC4B5.07c" FT /product="putative neuramidase (putative secreted protein)" FT /note="SC4B5.07c, possible neuraminidase (putative secreted FT protein), len: 648 aa; similar to several e.g. TR:D1001316 FT (EMBL:D01045) neuraminidase from Micromonospora FT viridifaciens (647 aa) fasta scores; opt: 286, z-score: FT 289.0, E(): 8.4e-09, (30.4% identity in 598 aa overlap). FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="HSSP:1EUR" FT /db_xref="InterPro:IPR013320" FT /db_xref="UniProtKB/TrEMBL:Q9ZBW1" FT /protein_id="CAA22361.1" FT /translation="MPPRTRRPFWLALATSCALAVSSPFPAHARPGDRAPAFGEQVLFD FT AARDPGGYACFRIPAIVRTTDGTLLAFAEGRVLDCADDGDIDIVLRRSLDGGRTWGPLR FT VVNDGGGDTHGNPAPVVDRATGRVLLLETYNAGRTDSADCAVPCARVPHVQHSDDGGRT FT WSAPRDLSPEILPPDWNSWYATGPVHGVQLTGGAHPGRLVVGVNAETWDGERSEMGVPP FT AGGWGRVTANHAALVVSDDGGEHWRTGATDTWPVAADGTFRQKPSELTLTERADGALLV FT SGREENGTDPGHRTQALSRDGGDSFAAPFRALPDLYAPQVQGAVLRLGNRILLSAPADP FT DRRRTMTVRSSRDGGATWDSADRGTVVTRDWAGYSDLVTVDDDTVGLLYEGGKTDARDE FT IRFARLTADRLAPPRGPDPTTPDLAANAAPAAVLGGAAPTTDGAVGGALAFDGADDAVR FT LPYDGRLALGEGDFTASLWFRYSAADGEQPLLWMGGIGTTQPQVWLRAEPDAGRVQGLI FT TARDGATAPRSAWVRTDRAYDDGRWHRLTLRRGGGRLTLFVDGSAAADAADVPGSVSRN FT SPFGVHIGERMDGRARFTGAVDDVQVWNSALTDTEIAAGVPPAAGRSTVLHLPLDRVDE FT AAADTGGSTDTGG" FT CDS complement(87738..88586) FT /transl_table=11 FT /gene="SCO6558" FT /gene_synonym="SC4B5.08c" FT /product="putative protein associated with oxidoreductase FT activity" FT /note="SC4B5.08c, protein associated with oxidoreductase FT activity, len: 282aa; similar to several eg. SW:FDHD_ECOLI FT FdhD protein from E. coli required for formate FT dehydrogenase activity at the posttranslational level, FT mechanism of action unknown (277 aa), fasta scores; opt: FT 337, z-score: 614.8, E(): 6e-27, (33.7% identity in 267 aa FT overlap) and SW:NARQ_BACSU NarQ protein from Bacillus FT subtilis required for nitrate assimilation mechanism of FT action unknown (262 aa) fasta scores; opt: 320, z-score: FT 501.0, E(): 1.3e-20, (32.7% identity in 272 aa overlap)." FT /db_xref="GOA:Q9ZBW0" FT /db_xref="InterPro:IPR003786" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZBW0" FT /protein_id="CAA22362.1" FT /translation="MGRVTERRKVIRIRDGAVSTRPDTLVAEEPLEIRLNGKPLAITMR FT TPGDDFALAAGFLVSEGVLAEQRDLQNIVYCAGATVDGSNTYNVVDVKTAPGVRIPDIT FT LERNVYTTSSCGLCGKASLDAVRTTARWPIADTPPVRVTPELLADLPDRLRASQRVFDR FT TGGLHAAALFTEDGELVDVREDVGRHNAVDKLVGRALQNADLPLSRSVLLVSGRASFEL FT AQKAVMAGIPVLAAVSAPSSLAVDLAAETGLTLVGFLRGSSMNVYAGADRVALRAAVGQ FT G" FT CDS complement(88619..89479) FT /transl_table=11 FT /gene="SCO6559" FT /gene_synonym="SC4B5.09c" FT /product="putative respiratory chain oxidoreductase" FT /note="SC4B5.09c, respiratory chain oxidoreductase, len: FT 286 aa; similar to the N-terminal region of many proteins FT involved in electron transfer e.g. TR:P77908 (EMBL:U73807) FT FdhA formate dehydrogenase alpha subunit from Moorella FT thermoacetica (893 aa), fasta scores; opt: 685, z-score: FT 791.8, E(): 0, (38.4% identity in 284 aa overlap). Contains FT PS00551 Prokaryotic molybdopterin oxidoreductases signature FT 1, PS00198 4Fe-4S ferredoxins, iron-sulfur binding region FT signature, PS00198 4Fe-4S ferredoxins, iron-sulfur binding FT region signature, Pfam match to entry PF00037 fer4, 4Fe-4S FT ferredoxins and related iron-sulfur cluster binding FT domains, score 40.00, E-value 2.4e-10 and Pfam match to FT entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding FT domains, score -5.70, E-value 0.11. Considering the FT corresponding homologies, this CDS may have previously been FT located directly upsteam of SC4B5.11c" FT /db_xref="GOA:Q9ZBV9" FT /db_xref="HSSP:1FRR" FT /db_xref="InterPro:IPR001041" FT /db_xref="UniProtKB/TrEMBL:Q9ZBV9" FT /protein_id="CAA22363.1" FT /translation="MTAIPLGVPRRLVEFTLDGQEARVPEGSTILDACRAAGKDVPTLC FT EGDTLAPKNACRVCVVDVEGARTLAPACSRKAEPGMVVRTDTERARHSRKVVLELLASS FT VDLSTTPSVAQWIKEYEAKPDRFGPDAARVDEEPRVDNDLYVRDYGKCILCYKCVDACG FT DQWQNSFAISVAGRGFDARISVEQDGPLTDSACVYCGNCIEVCPTGALSFKSEFDMRAA FT GTWDQERQTETTTVCAYCGVGCNLTLHVQDNEIVKVTSPHDNPVTHGNLCIKGRFGYQH FT VQNRD" FT misc_feature complement(88721..88777) FT /note="PS00551 Prokaryotic molybdopterin oxidoreductases FT signature 1." FT misc_feature complement(88838..89047) FT /note="Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins FT and related iron-sulfur cluster binding domains., score FT 40.00, E-value 2.4e-10" FT misc_feature complement(88859..88894) FT /note="PS00198 4Fe-4S ferredoxins, iron-sulfur binding FT region signature." FT misc_feature complement(88991..89026) FT /note="PS00198 4Fe-4S ferredoxins, iron-sulfur binding FT region signature." FT misc_feature complement(89228..89446) FT /note="Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur FT cluster binding domains, score -5.70, E-value 0.11" FT CDS complement(89476..91416) FT /transl_table=11 FT /gene="SCO6560" FT /gene_synonym="SC4B5.10c" FT /product="putative respiratory chain oxidoreductase" FT /note="SC4B5.10c, respiratory chain oxidoreductase, len: FT 646 aa; C-terminal region is similar to the N-terminal FT region of many proteins involved in electron transfer e.g. FT TR:O27592 (EMBL:AE000915) NADP-reducing hydrogenase, FT subunit C from Methanobacterium thermoautotrophicum (630 FT aa), fasta scores; opt: 121,4 z-score: 1170.7, E(): 0, FT (47.1% identity in 397 aa overlap). Contains PS00645 FT Respiratory-chain NADH dehydrogenase 51 Kd subunit FT signature 2." FT /db_xref="GOA:Q9ZBV8" FT /db_xref="InterPro:IPR019575" FT /db_xref="UniProtKB/TrEMBL:Q9ZBV8" FT /protein_id="CAA22364.1" FT /translation="MDALLGPPESSWEGADRSDADLRWARGGREARDRRDQLLPALHAL FT NDRVGWISEGALDYVCRRLTVPPAEAYGVATFYAMFSVRPRPATVLHVCTDLACTAAGA FT SRLCAAVESRLGPESGVKLERSPCLGLCERAPATLVIRAGESARPAQEDTPARPAFEDE FT AVQAEGGSGGAAPGDGGGTSRSSEAESGGGKGRRGRNTLHATAICAPATPDRAIAAATA FT PESAPTEPAPEAAVPQAGDPTLTLLHRIGTTDPTSLDDYRAHGGYTALRRAFALGPAAV FT IREVTDAGLVGRGGAAFPTGRKWQATAAQPDHPHYLVCNADESEPGTFKDRVLMEGDPY FT ALVEAMTIAAYATGAHRGYLYLRGEYPRALARLTHAIEQARTRGLLGDDVLGQGYAFDI FT EIRRGAGAYICGEETALFNSIEGRRGEPRSKPPFPVEKGLFGKPTVENNVETLVNVLPI FT LTMGAEAYAAIGTPTSTGPKLFCVSGTVARPGVYELPFGATLGELLALAGVRDNLRAVL FT LGGAAGGFVRPDELDIPLTFEGTREAGTTLGSGVVMAFDDTVPLPRLLLRIAEFFRDES FT CGQCVPCRVGTVRQEEALHRIADRTGAAAADDIALLREVGRAMRDASICGLGQTAWNAV FT ESAIDRLGAYE" FT misc_feature complement(89659..89694) FT /note="PS00645 Respiratory-chain NADH dehydrogenase 51 Kd FT subunit signature 2." FT CDS complement(91448..93376) FT /transl_table=11 FT /gene="SCO6561" FT /gene_synonym="SC4B5.11c" FT /product="putative respiratory chain oxidoreductase" FT /note="SC4B5.11c, respiratory chain oxidoreductase, len: FT 642 aa; similar to the C-terminal region of many proteins FT involved in electron transfer e.g. TR:P77908 (EMBL:U73807) FT FdhA formate dehydrogenase alpha subunit from Moorella FT thermoacetica (893 aa) fasta scores; opt: 1532, z-score: FT 1338.5, E(): 0, (43.1% identity in 619 aa overlap). FT Contains Pfam match to entry PF00384 molybdopterin, FT Prokaryotic molybdopterin oxidoreductases, score 95.80, FT E-value 6.2e-30. Considering the corresponding homolgies, FT this CDS may have previously been located directly FT downsteam of SC4B5.09c." FT /db_xref="GOA:Q9ZBV7" FT /db_xref="HSSP:1FDO" FT /db_xref="InterPro:IPR006657" FT /db_xref="UniProtKB/TrEMBL:Q9ZBV7" FT /protein_id="CAA22365.1" FT /translation="MRKRDRTPKTYTRLTHPLVRDSREAPLRRATWEEALDRTARGLTA FT ARGAFGMFSCARATNEMNYVAQKFARVVMGTHNVDSCNRTCHAPSVAGLSAAFGSGGGT FT SSYEEIEHTDVIVMWGSNARFAHPIFFQHVLKGIRGGARMYVVDPRRTSTAEWAESWLG FT PNVGTDIPLAHAVGREIIHAGLANEAFIERATTGYDDYKALVEPWTLSLAEKVTGVPAA FT AIRELAHAYARAERAQLCWTLGITEHHNGTDNVRALINLSLLTGHVGRYGSGLQPLRGQ FT NNVQGGGDMGAIPNRLPGFQDVLDPEVRRKFETAWDTVVEPHHGLTLTEMFEAMDEGTL FT RAVYCIGENPAQSEADAEQAVRRLRALDFLVVQDIFLTKTAELADVVLPATAGWAETEG FT TTTNSERRVQRVRRAVSPPGEAREDIDILCDLAARLGHDWKYADAEAVWNELRSLSPDH FT HGMTYARLEEHQGIQWPCPSTQELEPTYLHGRLWAQDPASRGRLAPFGIVRHDPPVDLT FT DEQYPIRLTTGRRLDSYNTGVQSGGYASPLRRGESVELCPEDAERYGVVVGEEVRVTSR FT RGSLLAPVWVDTALRPGLAFMSFHFPDEVDTNQLTIEANCPIAGTAEFKASAIRIEKVS FT ASGPALR" FT misc_feature complement(92081..92272) FT /note="Pfam match to entry PF00384 molybdopterin, FT Prokaryotic molybdopterin oxidoreductases, score 95.80, FT E-value 6.2e-30" FT CDS complement(93373..94344) FT /transl_table=11 FT /gene="SCO6562" FT /gene_synonym="SC4B5.12c" FT /product="putative oxidoreductase" FT /note="SC4B5.12c, probable oxidoreductase, len: 323; FT similar to several hypothetical /putative= probable FT 2-dehydropantoate 2-reductase from Archaeoglobus fulgidus FT (294 aa), fasta scores; opt: 245, z-score: 404.0, E(): FT 3.3e-15, (29.1% identity in 313 aa overlap)." FT /db_xref="GOA:Q9ZBV6" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9ZBV6" FT /protein_id="CAA22366.1" FT /translation="MKVAVLGAGAIGAYVGAALHRAGADVHLIARGPHLAAMRQYGVRV FT RSPRGDFTAHPRATDDPAEVGPVDYVFLGLKANSYAACGPLIEPLLHRTTAVVAAQNGI FT PWWYFHRHGGPYDGRRLESVDPAGAVSAVLAPERAVGCVVYAATELEQPGVVRHVEGTR FT FSIGEPGREVSPRCLALSEAMQSGGLKCPVEPDLRNDIWLKLLGNISFNPISALVRATM FT RQMCRHGGTREVIETMMTETLAVAAALGCEIGVSIERRLAGAERVGDHRTSTLQDLERG FT KPLELDVLLAAVVELAEITGVPVPTLRTVHALSDLLALRSAA" FT CDS 94548..95888 FT /transl_table=11 FT /gene="SCO6563" FT /gene_synonym="SC4B5.13" FT /product="putative integral membrane transporter" FT /note="SC4B5.13, probable integral membrane transporter, FT len: 446aa; similar to several eg. TR:Q51330 (EMBL:U40075) FT OxlT, the oxalate:formate exchange protein from Oxalobacter FT formigenes (418 aa), fasta scores; opt: 243, z-score: FT 382.3, E(): 5.3e-14, (26.1% identity in 421 aa overlap). FT Contains several possible membrane spanning regions. FT Contains Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter, score -99.90, E-value 0.013." FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9ZBV5" FT /protein_id="CAA22367.1" FT /translation="MSPPVAPPGWSRWLVPPAALSVHLSIGQAYAWSVFKPPLESALDL FT SGTQSALPFQLGIVMLGLSAAFGGTLVERHGPRWAMTVALICFSSGFLLSALGAAAGQY FT WLIVLGYGFVGGIGLGIGYISPVSTLIKWFPDRPGMATGIAIMGFGGGALIASPWSAQM FT LKSFGTDNSGIALAFLVHGLTYAVFMLLGVLLVRVPRPRERADGRPAPLEGVQVSARSA FT VRTPQFWLLWIVLCMNVTAGIGILEKAAPMITDFFSDTSTPVSVTAAAGFVALLSAANM FT AGRFGWSSASDLIGRKNIYRVYLGVGALMYTLIALFGDSSKPLFVLCALVVVSFYGGGF FT ATAPAYLKDLFGTYQVGAIHGRLLTAWSLAGVLGPLIVNWIADHQEEAGRHGSALYGTS FT FLIMIGLLVVGFVANELVRPVHARHHQPATPTQQEGNDVTRPQPESA" FT misc_feature 94587..95834 FT /note="Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter, score -99.90, E-value 0.013" FT CDS 96172..97122 FT /transl_table=11 FT /gene="SCO6564" FT /gene_synonym="SC4B5.14" FT /gene_synonym="fabH2" FT /product="3-oxoacyl-[acyl-carrier-protein] synthase II" FT /note="SC4B5.14, fabH2, 3-oxoacyl-[acyl-carrier-protein] FT synthase II, len: 316 aa; similar to many e.g. TR:P72392 FT (EMBL:X86475) FabH, 3-oxoacyl-[acyl-carrier-protein] FT synthase III from Streptomyces coelicolor (343 aa), fasta FT scores; opt: 547, z-score: 1039.5, E(): 0, (41.9% identity FT in 334 aa overlap)." FT /db_xref="GOA:Q9ZBV4" FT /db_xref="HSSP:1HNK" FT /db_xref="InterPro:IPR016038" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZBV4" FT /protein_id="CAA22368.1" FT /translation="MHQGSRITAVGHYQPARILTNEDLAGMVDTSDEWIRSRVGIRTRR FT IAGPDEPVDELAGHAAAKALASAGLTPADVDLVVVATSTAIDRSPNTAARVAARLGIPG FT PAALDLNVVCAGFTHALATADHAVRAGSASRALVVGADKMSEVVDWTDRTTCVLVGDGA FT GAAVVEACAPGEEPGIGPVLWGSVPEMGNAVRIEGTPPRFAQEGQSVYRWATTRLPAIA FT RQACERSGLEPADLAAVVLHQANLRIVEPLAAKIGAVNAVVARDVVESGNTSAASIPLA FT LSKLAERGEITTGDPALLFGFGGNLSYAGQVVRCP" FT CDS 97256..97933 FT /transl_table=11 FT /gene="SCO6565" FT /gene_synonym="SC4B5.15" FT /product="putative transcriptional regulator" FT /note="SC4B5.15, probable transcriptional regulator, len: FT 225aa; similar to many hypothetical /putative FT transcriptional regulators e.g. TR:O50514 (EMBL:AL009204) FT probable transcriptional regulator from Streptomyces FT coelicolor (231 aa), fasta scores; opt: 322, z-score: FT 457.0, E(): 3.7e-18, (35.2% identity in 199 aa overlap) and FT TR:P77347 (EMBL:D90785) NTA operon transcriptional FT regulator from Escherichia coli (221 aa), fasta scores; FT opt: 233, z-score: 348.7, E(): 4e-12, (27.1% identity in FT 192 aa overlap). Contains Pfam match to entry PF00392 gntR, FT Bacterial regulatory proteins, gntR family, score 56.90, FT E-value 5e-16." FT /db_xref="GOA:Q9ZBV3" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9ZBV3" FT /protein_id="CAA22369.1" FT /translation="MLSAGLPQGAVPRLERPGPLRDRVYEALLELITTRALQPGQHLVE FT SELAGHLGVSRQPVREALQRLNTEGWVDLRPAQGAFVHEPTEEEADQLLTVRTLLEAEA FT ARLAAANASSAGIAALEALCEEGERAVAAEDVDAAVACNARFHGKVMELAGNAVLAELA FT AQVDRRVRWYYTPVARQRGRQSWIEHRRLIAAVTERDEQAATRLMREHTEHTRRSYHAR FT GES" FT misc_feature 97325..97501 FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 56.90, E-value FT 5e-16" FT CDS 97996..99378 FT /transl_table=11 FT /gene="SCO6566" FT /gene_synonym="SC3F9.01" FT /gene_synonym="SC4B5.16" FT /product="putative ROK family protein" FT /note="SC3F9.01, unknown, partial CDS, len: >403 aa; FT similar to many members of the ROK (nagC/xylR) family e.g. FT NAGC_ECOLI N-acetylglucosamine repressor (406 aa), fasta FT scores; opt: 513 z-score: 578.8 E(): 5e-25, 28.6% identity FT in 388 aa overlap and GLK_STRCO glucokinase (EC 2.7.1.2) FT (glucose kinase) (317 aa), fasta scores; opt: 544 z-score: FT 570.9 E(): 1.4e-24, 34.4% identity in 317 aa overlap. FT Contains PS01125 ROK family signature and Pfam match to FT entry ROK PF00480, ROK family, score 164.11. Also similar FT to S. coelicolor SC7B7.05, probable transcriptional FT repressor (E(): 9.6e-25, 34.3% identity in 385 aa overlap)" FT /note="SC4B5.16, possible ROK family protein, partial CDS, FT len: 92aa; forms the C-terminal region of TR:O69941 FT (EMBL:AL023862) partial CDS, hypothetical ROK family FT protein on adjacent cosmid 3F9 from Streptomyces coelicolor FT (403 aa)." FT /db_xref="InterPro:IPR000600" FT /db_xref="UniProtKB/TrEMBL:Q8CJM5" FT /protein_id="CAD55380.1" FT /translation="MSGAVPCRTLLCPLSGESSQQFVRDFFPHPAPTATFPPKASHADK FT SRTWPETGGPKADRGGEGLVRRMTARPANTHQARLLQLLRDGGPNSRAQLGDQVDLSRS FT KLAVEVDRLLETGLVVADGLAASRGGRRSHNVRLNPELRFLGVDIGATSVDVAVTNAEL FT EILGHINQPLDVREGPVAVFEQVLSMAAKLRASGLAEGFDGAGIGVPGPVRFPEGVPVA FT PPIMPGWDGFPVREALSQELGCPVMVDNDVNLMALGEQHAGVARTQHDFLVVKIGTGIG FT CGIVVGGEVYRGTTGSAGDIGHIQAVPDGRQCACGNRGCLEAHFSGAALARDATEAAEQ FT GQSAELANRLEANGGLSAADVAAAAAAGDATALDLIREGGRSTGQVIAGLVSFFNPGLV FT VIGGGVTGLGHNLLAAIRTQVYRQSLPLATGNLPIVLGELGPTAGVIGAARLISDHLFS FT PA" FT misc_feature 98167..98273 FT /note="Overlap with Streptomyces coelicolor cosmid 3F9 FT (EMBL:AL023862)." FT misc_feature complement(98167..109289) FT /note="real overlap with cosmid 4B5; unfinished" FT misc_feature 98431..98985 FT /note="Pfam match to entry ROK PF00480, ROK family, score FT 164.11" FT misc_feature 98821..98904 FT /note="PS01125 ROK family signature" FT RBS 99576..99579 FT /note="possible RBS upstream of SC3F9.02" FT CDS 99589..101106 FT /transl_table=11 FT /gene="SCO6567" FT /gene_synonym="SC3F9.02" FT /product="ABC transporter ATP binding protein" FT /note="SC3F9.02, ABC transporter ATP binding protein, FT len:505 aa; similar to many sugar transport proteins e.g. FT ARAG_ECOLI l-arabinose transport atp-binding protein (504 FT aa), fasta scores; opt: 1312 z-score: 1412.8 E(): 0, 42.1% FT identity in 501 aa overlap andRBSA_HAEIN ribose transport FT atp-binding protein rbsA (493 aa), fasta scores; opt: 1160 FT z-score: 1216.7 E(): 0, 40.7% identity in 489 aa overlap. FT Contains PS00017 ATP/GTP-binding site motif A (P-loop), FT PS00211 ABC transporters family signature and Pfam match to FT entry ABC_tran PF00005, ABC transporters, score 197.70" FT /db_xref="GOA:O69942" FT /db_xref="HSSP:1G6H" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:O69942" FT /protein_id="CAA19625.1" FT /translation="MAPEPPLLSMSGITKSFPGVRALDGVDLDVQAGEVHCLLGQNGAG FT KSTLIKVLAGAHQPDTGTIRWRGEEVTLRSPIAAMRLGIATIYQELDLVEHLSVAENVH FT LGHEPTAAGFVVRGRAAKASTAALLKRLGHPEVDPGRLVGELSAAQQQIVSMARALSHD FT VRLIVMDEPSAALDPDEVDNLFRIVADLTADGVAVVYISHRLEEIRRIGDRVTVLKDGR FT AVAGGLPAESTPTSEVVALMTGRNVEYVFPERPAAPPTGEPVLSVKGLSRAGEFDRLDL FT EVRPGEIVGLAGLVGSGRSEILETVYGARKASTGQVLVDGRPLRPGSVRAAVRAGLGLA FT PEERKAQALLMLESVTRNVSVSAMSRFSRGGWIDRGAELGAAHKATRELSLRPDNPAVP FT VRTLSGGNQQKAVLARWLLRGCRVLLLDEPTRGVDVGARAELYAVIRRLADEGLAVLLV FT SSEVPEVLGLADRVLVLREGRVVHEAPARELDEHRVLDLVMEGSPAS" FT misc_feature 99685..100251 FT /note="Pfam match to entry ABC_tran PF00005, ABC FT transporters, score 197.70" FT misc_feature 99706..99729 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 100795..100839 FT /note="PS00211 ABC transporters family signature" FT RBS 101087..101091 FT /note="possible RBS upstream of SC3F9.03" FT CDS 101103..102122 FT /transl_table=11 FT /gene="SCO6568" FT /gene_synonym="SC3F9.03" FT /product="ABC transporter integral membrane protein" FT /note="SC3F9.03, ABC transporter integral membrane protein, FT len: 339 aa; similar to many involved in sugar transport FT e.g. RBSC_BACSU ribose transport system permease protein FT (323 aa), fasta scores; opt: 700 z-score: 958.9 E(): 0, FT 39.5%identity in 314 aa overlap" FT /db_xref="GOA:O69943" FT /db_xref="InterPro:IPR001851" FT /db_xref="UniProtKB/TrEMBL:O69943" FT /protein_id="CAA19626.1" FT /translation="MTQHVSPPRGSTDKAAPVEGPPAWRVRLGRADVRTLTLLGVLAAL FT VLIGGITQPDAFLDTRNLQLVLTQASVIGIVTVGVTFVIISGGIDLSVGAIVALSSVWA FT TTVATQEYGFAGILFTAIVVGVGCGLVNGLLISFGGMVPFIATLAMLASARGLALQITD FT GRTQVVTVPSVLDLAERDSYVLGIPPLVLVFAAVTVVGWLVLNRTTFGRRTVAVGGNAE FT AARLAGIDVRRQRLYLYLLSGLCCGIAAFLLVALAGSGQNTNGNLYELDAIAAAIIGGT FT LLTGGRGHILGSVLGVLIFTTITNIFALNNLQSDVQQIAKGAIIVAAVLVQRRTASTH" FT RBS 102122..102125 FT /note="possible RBS upstream of SC3F9.04" FT CDS 102140..103186 FT /transl_table=11 FT /gene="SCO6569" FT /gene_synonym="SC3F9.04" FT /product="putative secreted solute binding protein" FT /note="SC3F9.04, probable secreted solute binding protein, FT len: 348 aa; similar to many e.g. RBSB_HAEIN FT D-ribose-binding periplasmic protein precursor (292 aa), FT fasta scores; opt: 341 z-score: 284.7 E(): 1.2e-08, 29.2% FT identity in 271 aa overlap. Contains N-terminal signal FT sequence and appropriately positioned PS00013 Prokaryotic FT membrane lipoprotein lipid attachment site" FT /db_xref="InterPro:IPR001761" FT /db_xref="UniProtKB/TrEMBL:O69944" FT /protein_id="CAA19627.1" FT /translation="MTKLTSRRGMLFGAAAVSAGAVLAGCTSNDPDGGDDKAAADTQPA FT ADDKPGKPVTIGYAGPQADHGWLNAVNDQAKKRAEKYSEITMEITEGSNDTAQQIGQIE FT TLINKKVDVLVILPADGKALTQVGLKAMRAGIPVINLDRIFNSPQAYRCWVGGDNYGMG FT LNAAHYIGEKLKDKSDAKVIELAGIDNLELTQQRTQGFDDGLKNYPNIKKVARQAAEFT FT VESGQAKMAQLLQAQSDFDAMWNHDDDQGVGALRAIEQAGRDDFLMVGGAGALSAFQAI FT KADSGVLKATVLYPPTMAASAIDLARALGQGKGVSGLAEFEIPSTVTCYSAVVDKDNVD FT QYMSTGFK" FT misc_feature 102185..102217 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS 103258..103263 FT /note="possible RBS upstream of SCF9.05" FT CDS 103272..104564 FT /transl_table=11 FT /gene="SCO6570" FT /gene_synonym="SC3F9.05" FT /product="putative oxidoreductase" FT /note="SC3F9.05, possible oxidoreductase, len: 430 aa; FT similar to e.g. Zymomonas mobilisTR:P75002 (EMBL:Z80356) FT glucose-fructose oxidoreductase (433 aa), fasta scores; FT opt: 310 z-score: 305.5 E(): 8.4e-10, 27.2% identity in FT 426 aa overlap" FT /db_xref="GOA:O69945" FT /db_xref="HSSP:1EVJ" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:O69945" FT /protein_id="CAA19628.1" FT /translation="MGQPQQPEGAGAEEAAAGTDSGTDTGTGAGAGAATGASATRPPLR FT VGMVGYAFMGAAHSQGWRTAGRVFDLPLNPVLAAICGRDADAVRLAADRHGWASTETDW FT RTLVERDDIDLVDICTPGDSHSEIALAALAAGKHVLCEKPLANTVEEAQAMTRAAEEAA FT ARGQLAMVGFNYRRVPATALARRMVAEGRVGRLRHLRVTYLQDWLVDPKAPLTWRLRKE FT LAGSGALGDLGAHIVDLAQYLSGERIAGVSALTETFVRERPLPAGAPRGLSAGSADGVT FT GQVTVDDAAVFTGRLTSGALVSFEATRYATGRKNALRIELNGERGSLAFDLERLNELSY FT HDGTEPGEHAGFRRILVTEPEHPYLEAWWPPGHGLGYEHTFVHQARDLVHAVAEGRGPE FT PSFADGLQVQRVLAAVEESAEKNSVYTPITP" FT RBS 104564..104569 FT /note="possible RBS upstream of SC3F9.06" FT CDS 104581..105579 FT /transl_table=11 FT /gene="SCO6571" FT /gene_synonym="SC3F9.06" FT /product="putative DNA-binding protein" FT /note="SC3F9.06, possible DNA-binding protein, len: 332 aa; FT similar to TR:Q9A7T9 (EMBL:AE005838) Caulobacter crescentus FT hypothetical protein CC1631, 351 aa; fasta scores: opt: 552 FT Z-score: 641.5 E(): 4.2e-28; 34.940% identity in 332 aa FT overlap. Contains possible helix-turn-helix motif at FT residues 55 to 76 (Score 1148, +3.10 SD)" FT /db_xref="GOA:O69946" FT /db_xref="InterPro:IPR013022" FT /db_xref="PDB:2ZDS" FT /db_xref="UniProtKB/TrEMBL:O69946" FT /protein_id="CAA19629.1" FT /translation="MPRNFTLFTGQWADLPLEEVCRLARDFGYDGLELACWGDHFEVDK FT ALADPSYVDSRHQLLDKYGLKCWAISNHLVGQAVCDAIIDERHEAILPARIWGDGDAEG FT VRQRAAAEIKDTARAAARLGVDTVIGFTGSAIWHLVAMFPPAPESMIERGYQDFADRWN FT PILDVFDAEGVRFAHEVHPSEIAYDYWTTHRALEAVGHRPAFGLNFDPSHFVWQDLDPV FT GFLWDFRDRIYHVDCKEARKRLDGRNGRLGSHLPWGDPRRGWDFVSAGHGDVPWEDVFR FT MLRSIDYQGPVSVEWEDAGMDRLQGAPEALTRLKAFDFEPPSASFDAAFNS" FT RBS 105856..105860 FT /note="possible RBS upstream of SC3F9.07" FT CDS 105867..109583 FT /transl_table=11 FT /gene="SCO6572" FT /gene_synonym="SC3F9.07" FT /product="putative glycosyl hydrolase (putative secreted FT protein)" FT /note="SC3F9.07, possible glycosyl hydrolase (putative FT secreted protein), len: 1238 aa; similar to TR:Q9K473 FT (EMBL:AL359215) putative glycosyl hydrolase from FT Streptomyces coelicolor (962 aa) fasta scores; opt: 3614, FT Z-score: 3774.0, 63.899% identity (65.074% ungapped) in 831 FT aa overlap. Contains possible N-terminal region signal FT peptide sequence" FT /db_xref="GOA:O69947" FT /db_xref="HSSP:1OD3" FT /db_xref="InterPro:IPR000601" FT /db_xref="UniProtKB/TrEMBL:O69947" FT /protein_id="CAA19630.1" FT /translation="MHRTRLKSTSTARRPRLRTTLALFTGLLLAVGTPATVAGAHPGHP FT EHDETAAAAEGQFQQVPLAKGEPEMGEPMSLAVLPDRSVLHTARDGTLRLTDQGGVTKV FT AGKIPVYNHDEEGLQGVGIDPDFENNRAIYLYYAPPLDTPAGDAPENGTAEDFKPFDGV FT NRLSRFVLNANGTLDMASEKKVLDVAASRGTCCHVGGDIAFDAEGNLYLSTGDDTNPFA FT SDGYTPIDERADRNPAFDARRSAGNTNDLRGKLLRIKVAEDGSYTVPEGNLFEPGTEKT FT RPEIYAMGFRNPFRISVDKKTGTVYVGDYGPDAGAADPKRGPAGQVEFAKVTKAANFGW FT PFCTGDNDPYVDYDFATKTSGETFDCAAPKNTSPHNTGLTDLPPAQAAWIPYDDDSVPE FT FGSGSESPMGGPVYRYDPDLDSSVKFPEEYDGDFFAGEFGRRWIKRIEQTEDGAVAKIN FT DFPWTGTQIMDMEFGPDGALYVLDYGLSWFQGDKDSALYRIENAADGFSPIAEVSANKT FT SGAAGLKVAFTATAKDADSPDLTYGWDFGDGTKGEGLTPTHKYKKVGTYTATFTAKDPE FT GNTGNASVRIVVGNTEPKVVIETPGNGTLLPMGQPIPFKVKVTDPEETIDCSKVKVAYS FT LGHDSHAHELTSEMGCEGTLNPPPGDGGHDPNANIYGVVGASYTDGGANGQEALTGTAR FT TVIQPPHRQAEHFTAQQGVSPIDKTGANGGKTVGNIDDGDWISFSPYKFDGQKKLTVRA FT SSGGAGGYIEVRTGSPTGPLHGSAYIPPTGSWETFQNVDVPLRALPKKTTDVYLVFKGG FT EGALYDIDDFEFSKEPFKAGKKVLVFSKTAGFRHDSIPAGIAALKELGTPAGISVTATE FT EAGQFTTANLAKYDAVAFLSTTGDVLNADQQKAFENYVKNGGGYMGIHAAADTEYDWEF FT YGGLVGAYFDSHPAIQKATVRVEDHDHPATAHLDDTWEHTDELYNYRTNPREQAKVLAT FT LDETTYAGGNMKGDHPIAWCQNYGGGRSFYTGLGHTKESYADETFRGHLLGGMQYATGQ FT VKANCKPGKGYRDIFNGQTLDGWKQAGPGKFNVKNGVLESEGGMGLLWYQAKELKSYSL FT KLDWKMRGDDNSGVFVGFPASDDPWSAVNKGYEIQIDATDAVDRTTGAIYTFKAANIKA FT RDQVLRPPGQWNSYEIKVQGERLQVFLNGVKINDFTNKDPERSLTDGYIGLQNHGADDQ FT VSFRNIQLKELPS" FT RBS 109740..109746 FT /note="possible RBS upstream of SC3F9.08" FT CDS 109753..111006 FT /transl_table=11 FT /gene="SCO6573" FT /gene_synonym="SC3F9.08" FT /product="putative secreted protein" FT /note="SC3F9.08, probable secreted protein, len: 417 aa; FT some similarity to many eukaryotic myo-inositol-1-phosphate FT synthases e.g. INO1_SPIPO (510 aa), fasta scores; opt: 159 FT z-score: 190.1 E(): 0.0022, 28.1% identity in 423 aa FT overlap, and to Archaeoglobus fulgidus TR:O28480 FT (EMBL:AE000979) AF1794 (392 aa), fasta scores; opt: 546 FT z-score: 713.5 E(): 1.6e-32, 37.0% identity in 397 aa FT overlap. Contains possible N-terminal signal sequence and FT appropriately positioned PS00013 Prokaryotic membrane FT lipoprotein lipid attachment site" FT /db_xref="GOA:O69948" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:O69948" FT /protein_id="CAA19631.1" FT /translation="MSASPSASSRGSRTGVWLIGARGSVATTVVAGCAAVTAGLHPPTG FT MVTETPDFAGAGLPALPALVFGGHDTVDCPLPKRAEALAAGGVLPHGLPSAVHAELAAA FT DREIRPGGPLPGDTRDEEELIAAFAADITDFARRSGVDRTVVVNVASTEPAPAGGALPA FT SSLYAAAALRAGCPYVNFTPSTGLHHPALSAPAEASGLPYAGRDGKTGQTLLRSVLGPM FT FAQRALAVRAWSGTNLLGGGDGAALADPAAAAAKNAGKERVLADTLGAPVEGEVHIDDV FT PVLGDWKTAWDHIAFDGFLGARMFLQTTWQGCDSSLAAPLVLDLARLVARAHQRGLSGP FT LGELGFFFKDPVGDGPSALAEQYGELKRFAGRLREDADGAPVDGDGGEGGANGSAGQSG FT DAVAVRPGGRGVEGGAGR" FT misc_feature 109819..109851 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS 111003..112094 FT /transl_table=11 FT /gene="SCO6574" FT /gene_synonym="SC3F9.09" FT /product="putative membrane protein" FT /note="SC3F9.09, putative membrane protein, len: 363 aa; FT similar to TR:Q9Z4Y9 (EMBL:AL035707) Streptomyces FT coelicolor putative transferase SCE29.11c, 291 aa; fasta FT scores: opt: 666 Z-score: 604.6 E(): 4.8e-26; 51.282% FT identity in 312 aa overlap. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:O69949" FT /db_xref="InterPro:IPR000537" FT /db_xref="UniProtKB/TrEMBL:O69949" FT /protein_id="CAA19632.1" FT /translation="MSRATAAARVTAGPSGATAASSRPPAGAAGVPGAASGTTGPPLAT FT AEASPRSARLGAWAELLRLPALFTVPGDALAGAAAAGVRPGPRTLLAIGSSLCLYEAGM FT ALNDWADRAEDAAERPHRPLPSGRIRPAAALTAAGALTGAGLALAAGAGRPALAVAAPL FT AATVWAYDLALKHTPAGPAAMAAARGLDLLLGAAATGGGTRAALPCAALLGSHTLAVTA FT VSRRETTGGSVLAPLAALATTGALTGLVARRRTRLPAGRRAAAAPGLSGSTPAPAVTDA FT LAAALGAAYAATAARPYFHAALNPSPPLTRRAVGGGIRATIPLQAALAARSGASATSLL FT VAALAPAGRWFAKRSAMRKVSIT" FT RBS 112078..112081 FT /note="possible RBS upstream of SC3F9.10" FT CDS 112091..113038 FT /transl_table=11 FT /gene="SCO6575" FT /gene_synonym="SC3F9.10" FT /product="conserved hypothetical protein SC3F9.10" FT /note="SC3F9.10, unknown, len: 315 aa; some similarity to FT MOCC_RHIME rhizopine catabolism protein MocC (325 aa), FT fasta scores; opt: 127 z-score: 216.9 E(): 7.2e-05, 33.5% FT identity in 167 aa overlap" FT /db_xref="InterPro:IPR013022" FT /db_xref="UniProtKB/TrEMBL:O69950" FT /protein_id="CAA19633.1" FT /translation="MSRHPKQGPNGAGDGPATHPLRFGYGTNGLADLRLDDALALLADL FT GYDGVGLTLDHMHLDPLADDLAARTRRLARRLDTLGLGVTVETGARYVLDPRRKHGPSL FT LDPDPQDRARRTGLLLRAVDVAAELGAHAVHCFSGVTPGGTDEDTAWKRLAEALAPVLD FT AAATAGVPLAVEPEPGHLLATVADFHTLRGALGDPEHLGLTLDIGHCQCLEPLPPADCV FT RAAAPWLRHVQIEDMRRGVHEHLPFGDGEIDFPPVLEALAATGYQGLTVVELPRHSHAG FT PHYAERSLPFLRRAAPAPPPPPRTNRSGEPSATH" FT RBS 113041..113044 FT /note="possible RBS upstream of SC3F9.11" FT CDS 113052..113789 FT /transl_table=11 FT /gene="SCO6576" FT /gene_synonym="SC3F9.11" FT /product="conserved hypothetical protein SC3F9.11" FT /note="SC3F9.11, unknown, len: 245 aa; sim ilar to another FT from Streptomyces coelicolor TR:Q9Z4Z1 (EMBL:AL035707) FT SCE29.09C (236 aa) fasta scores; opt: 416, Z-score: 467.6, FT E(): 2.1e-18, 45.455% identity (52.083% ungapped) in 220 aa FT overlap ." FT /db_xref="UniProtKB/TrEMBL:O69951" FT /protein_id="CAA19634.1" FT /translation="MTQPHTAHVTPDTQDADGTPDGQDAQGTTPAHVPPADLRAALTTR FT LGGAARAWLDQALDEAAAHPGTHGPISVWELRLAEAGRRCGPAHADAARVLVLHAARAD FT TGALTRVYSQGTADERRAVLHALPHLVPGPDALPLVEDALRTNDTRLVAAALGPYAARH FT LDAHQWRHAVLKCLFTGVAVDSVADLALRAHGDDELARMLADYAAERTAADRTVPEDLH FT RVLALTESGRPAPGTADPHGKES" FT RBS 113778..113783 FT /note="possible RBS upstream of SC3F9.12" FT CDS 113789..114637 FT /transl_table=11 FT /gene="SCO6577" FT /gene_synonym="SC3F9.12" FT /product="conserved hypothetical protein SC3F9.12" FT /note="SC3F9.12, unknown, len: 282 aa; similar to FT hypothetical proteins from several organisms e.g. FT YD83_METJA MJ1383(256 aa), fasta scores; opt: 347 z-score: FT 391.9 E(): 1.3e-14, 28.5% identity in 260 aa overlap" FT /db_xref="GOA:O69952" FT /db_xref="InterPro:IPR012022" FT /db_xref="UniProtKB/TrEMBL:O69952" FT /protein_id="CAA19635.1" FT /translation="MRIFDPHIHMTSRTTDDYEAMYAAGVRALVEPSFWLGQPRTSPDS FT FRDYFDALLGWEPFRAAQYGIAHHCTIALNPKEANDPRCRPVLDELPRYLVKDRVVAVG FT EIGYDSMTPAEDTALATQLQLAADHGLPALVHTPHRDKLAGLRRTLDAVRESALPTERV FT LVDHLNETTVKEAKDSGAWLGFSVYPDTKMDEARMVALLREYGPEQVLVNSAADWGRSD FT PLKTRKVGDLMLAEGFTDDDVDRVLWRNPVAFYGLSGRLELDVAAGDATHEGNSILRGG FT E" FT RBS 114631..114634 FT /note="possible RBS upstream of SC3F9.13" FT CDS 114641..115816 FT /transl_table=11 FT /gene="SCO6578" FT /gene_synonym="SC3F9.13" FT /product="hypothetical protein SC3F9.13" FT /note="SC3F9.13, unknown, len: 391 aa; contains PS00730 AP FT endonucleases family 2 signature 2" FT /db_xref="GOA:O69953" FT /db_xref="InterPro:IPR018246" FT /db_xref="UniProtKB/TrEMBL:O69953" FT /protein_id="CAA19636.1" FT /translation="MRFRHPDGSTVHLAYCTNVHPAETLDGVLAQLRDHCEPVRKRLGR FT DRLGIGLWLARDAAHALVTDPAALRGLRTELDRRGLEFVTLNGFPYEGFGAEEVKYRVY FT KPDWADPERLEHTTSLARLLAGLLPDDVADGTISTLPLAWRTAYDDTRADKARAALVTL FT AERLDALQELTGRSIRVGLEPEPGCVVETTHDAIAPLTAIAHDRIGVCVDTCHLATSFE FT DPHTALDALTAARVPVVKSQLSAALHAEHPADPAVREALAAFAEPRFLHQTRTTTPSGG FT LHGTDDLDEALADGGPLPDTAPWRAHFHVPLHAAPAAPLTSTLPVLKAALTRLVGGPHP FT LTRNLEVETYTWQALPPELRPRARAQLTDGIAAELTLARDLLTDLGLKELP" FT misc_feature 115265..115288 FT /note="PS00730 AP endonucleases family 2 signature 2" FT RBS 115802..115806 FT /note="possible RBS upstream of SC3F9.14" FT CDS 115813..117210 FT /transl_table=11 FT /gene="SCO6579" FT /gene_synonym="SC3F9.14" FT /product="hypothetical protein SC3F9.14" FT /note="SC3F9.14, unknown, len: 465 aa, similar to TR:Q9Z4Z4 FT (EMBL:AL035707) hypothetical protein from Streptomyces FT coelicolor (462 aa) fasta scores; opt: 2206, Z-score: FT 2466.5, 70.575% identity (70.889% ungapped) in 452 aa FT overlap." FT /db_xref="GOA:O69954" FT /db_xref="InterPro:IPR017849" FT /db_xref="UniProtKB/TrEMBL:O69954" FT /protein_id="CAA19637.1" FT /translation="MTRPTPSDGPTPLLVLDVVGLTPRLLDHMPHLKQLGQSGSRAPLG FT TVLPAVTCAAQSTFLTGTMPSEHGIVGNGWYFRELGDVLLWRQHNGLVAGDRLWDAARR FT AHPGYTVANICWWYAMGADTDFTVTPRPVYYADGRKEPDCYTRPPALHDELTDKLGTFP FT LFHFWGPGADLVSSQWIIDATRHIMATRHPDLTLCYLPHLDYDLQRFGPDDPRSLKAAA FT DLDAALAPLLDDARAEGRTVVALSEYGITPVSRPVDINRALRRAGLLEVHTQDGMEYLD FT PMASRAFAVADHQVAHVYVRRPEDLDATRAALDGLPGIEQLLDDEGKKAQHLDHPRAGE FT LVAVAEPDAWFTYYYWLDDDRAPDFAQLVEIHRKPGYDPVELFMDPLDPYVKVKAAGAL FT ARKKLGMRYRMAVVPLDASPIRGSHGRLPASDDDGPLLICSTPRAVGDRVAATDVKQLL FT LRLAGLG" FT RBS 117310..117315 FT /note="possible RBS upstream of SC3F9.15" FT CDS 117325..118539 FT /transl_table=11 FT /gene="SCO6580" FT /gene_synonym="SC3F9.15" FT /product="hypothetical protein SC3F9.15" FT /note="SC8A6.01, unknown, partial CDS, len: >215 aa; FT overlaps and extends SC3F9.15" FT /note="SC3F9.15, unknown, partial CDS len: >224 aa" FT /db_xref="InterPro:IPR012307" FT /db_xref="UniProtKB/TrEMBL:Q8CJM4" FT /protein_id="CAD55381.1" FT /translation="MTPFTDSSRTDAGTDPSADGPGESLRRALGVNRRRFLSTCTAVAA FT GAVAAPVFGASPALAHDRDRDHDHGHGHGHGHGQILVPADKRGIILYTVRDATARDPLA FT SDLPSGFREVFKQLSRHGYRQVEFAGYNQHANAPGGASLESVKGARLLRSWLDDYGLRA FT QGNHGFIPSSWPLTQADKDTFKKHLEIANILGMDHMGTGGDPTGSSYRADWDVAADKWN FT ALGAIAHREGIKLYTHNHDSAYGFLLDGGPLDDQGRPTRSSGIRKLEYFLKVTDPRVVW FT LEMDIFWAHVAQYKFHEYTAHDGSTRKNVFDPAGLVVRNNRRYPLFHAKDGVVSTTNGM FT GYDMVPFGTGVIDYTTFFSRVGQRNYHNPMIEDDNSPSATDPSQSLREAKISYDNLAAL FT RKRRH" FT stem_loop 118546..118600 FT /note="hairpin loop with 23 bp stem" FT CDS complement(118619..120049) FT /transl_table=11 FT /gene="SCO6581" FT /product="putative transmembrane transport protein" FT /note="SC8A6.02c, probable transmembrane transport protein, FT len: 476 aa; some similarity to e.g. TR:Q51330 (EMBL:U4007 FT 5) oxalate:formate antiport protein from Oxalobacter formig FT enes (418 aa), fasta scores; opt: 226 z-score: 230.1 E(): 1 FT .4e-05, 24.1% identity in 436 aa overlap" FT /db_xref="GOA:O87836" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:O87836" FT /protein_id="CAA19774.1" FT /translation="MGQGALARSFDARGAIDMTTTDVTRVAAYREVTDRNGRVYRVGES FT DIDLMGRKRKWMVILPWIGMMGISSAEYAFASAEDTLHEAQHWSSGSIYWMMTAWVFCQ FT AAVAFPAGRLRESGKLPARWAMMLGSAGTLLGYLSLAFAPHVSLAFIGFGVFSGMGAGM FT VYATCVNMVGKWYPERRGGKTGFVNGGFAYGSVPFVFIFHGYMDTSNFRWVLVSAGVFL FT AAMVAIAGFYFRDPPKNWWPAAVDPLNPPADPRARRSLEKNPPAVKQYSPMEAWKTGRV FT ALMWFCLACTSGVNIFGIAFQVDIGEEAGFAAGVVAAAMSLKAIVNGTGRGVIGWLSDL FT YGRKQCLLYVCAILGLAQFGIIWSAEIKNLPLFLVFSAISGFGGGAIFPMFAALTADYF FT GENNNATNYGMVYSSKLVSGLGAGMGSVVVGVWGYNGAFSLAGSISIFAGFVALSLRPP FT GRPKGKRVTPNPQPLGEG" FT CDS complement(120122..122266) FT /transl_table=11 FT /gene="SCO6582" FT /product="conserved hypothetical protein" FT /note="SC8A6.03c, unknown, len: 714 aa; similar to many FT hypothetical proteins including several from each of the FT arche ons Archaeoglobus fulgidus TR:O28341 (EMBL:AE000970) FT conser ved hypothetical protein AF1938(673 aa), fasta FT scores; opt: 960 z-score: 1289.8 E(): 0, 35.6% identity in FT 693 aa overl ap and Pyrococcus horikoshii D1028624 FT (EMBL:AB009518) hypot hetical protein PHCV016 (460 aa), FT fasta scores; opt: 1280 z -score: 1246.9 E(): 0, 44.3% FT identity in 461 aa overlap. Co ntains PS00216 Sugar FT transport proteins signature 1. Also s imilar to S. FT coelicolor hypothetical protein SC9B10.09 (E() : 6.1e-15, FT 33.9% identity in 375 aa overlap)" FT /db_xref="GOA:O87837" FT /db_xref="HSSP:1IUK" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:O87837" FT /protein_id="CAA19775.1" FT /translation="MAEDRLARVRGLLDAVRGEGRTALTAPEGKVLADAYGIAVPGEEL FT ARDVDEAVACAARFGGPVVMKIVSPDILHKTDAGGVVVGVEGAADVRAAFCRIVDNARA FT YDASARIEGVQIQELLPQGQEVIVGAVTDPTFGKVVAFGLGGVLVEVLKDVTFRLAPVD FT ADEALSMLDSIRAAEVLRGVRGQAGVDRWAVAEQIRRVSELVADFPEIAEVDLNPVIAT FT PEGAVAADIRVILATDTPKERRRYTREEILTSMRRLMQPASVAVIGASGEPGKIGNSVM FT RNLVDGGFAGEIHPVNPKADDILGRKAYKSVTDVPGEVDVAVFAIPARFVAAALEEVGR FT KRIPNAVLIPSGFAETGEQALQDEIVAVAERHGVRLLGPNIYGYYSTWQDLCATFCTPY FT DVKGGVALTSQSGGIGMAILGFARTTKTGVSAIVGLGNKSDLDEDDLLTWFGEDPHTEC FT IAMHLEDLKDGRAFVEAARATVPRKPVVVLKAGRTAAGAKAAGSHTGALAGDDAVYDDI FT LRQAGVIRAPGLNEMLEYARALPVLPAPEGDNVVIITGAGGSGVLLSDAVTDNGLSLME FT IPPDLDRAFRAFIPPFGAAGNPVDITGGEPPSTYEATIRLGLEDPRIHALVLGYWHTIV FT TPPMVFAELTARVVAEFRERGVEKPVVASLAGDVEVEEACQYLFERGVVAYPYTTEKPV FT AVLGAKYRWARAAGLLGGGS" FT misc_feature complement(121229..121276) FT /note="PS00216 Sugar transport proteins signature 1" FT CDS complement(122271..123503) FT /transl_table=11 FT /gene="SCO6583" FT /product="putative transferase" FT /note="SC8A6.04c, probable transferase, len: 410 aa; highly FT similar to TR:O06644 (EMBL:U82167) formyl-CoA transferase FT from Oxalobacter formigenes (428 aa), fasta scores; opt: 95 FT 4 z-score: 1732.0 E(): 0, 50.7% identity in 428 aa overlap. FT Also similar to many dehydratases e.g. CAIB_ECOLI L-carnit FT ine dehydratase (EC 4.2.1.89) (405 aa), fasta scores; opt: FT 285 z-score: 317.7 E(): 1.9e-10, 26.2% identity in 427 aa o FT verlap" FT /db_xref="GOA:O87838" FT /db_xref="HSSP:1P5H" FT /db_xref="InterPro:IPR017659" FT /db_xref="UniProtKB/Swiss-Prot:O87838" FT /protein_id="CAA19776.1" FT /translation="MTAKALEGIRVLDMTHVQSGPSATQLLAWLGADVVKLEAPHGDIT FT RGQLRDLPDVDSLYFTMLNCNKRSITLNTKSERGKEILTELIRRSDVMVENFGPGAVDR FT MGFTWDRVKEINPRIVYASIKGFGEGPYTAFKAYEVVAQAMGGSMSTTGFEDGPPLATG FT AQIGDSGTGVHVVAGILAALYQREHTGRGQRVNVAMQHAVLNLCRVKLRDQQRLSHGPL FT AEYPNEDFGDEVPRSGNASGGGQPGWAVKCAPGGPNDYVYVIVQPVGWQPLSELIGRPE FT LAEDPEWATPRARLPKLNKMFQLIEEWSSTLPKWEVLERLNAHNIPCGPILSTKEIIED FT DSLVANEMVVTVPHPERGEFVTVGSPLKLSDSPVEVTSSPLLGEHNEEVYVGELGLGDE FT ELRLLKSSGVI" FT RBS complement(123512..123516) FT /note="possible RBS upstream of SC8A6.04c" FT CDS complement(123515..125197) FT /transl_table=11 FT /gene="SCO6584" FT /product="putative TPP-requiring enzyme" FT /note="SC8A6.05c, probable TPP-requiring enzyme, len: 560 a FT a; similar to many e.g. ILVB_MYCTU probable acetolactate FT synthase (EC 4.1.3.18) (547 aa), fasta scores; opt: 733 FT z-sco re: 1305.6 E(): 0, 36.4% identity in 557 aa overlap. FT Contai ns PS00187 Thiamine pyrophosphate enzymes signature FT and Pfam match to entry PF00205 TPP_enzymes, Thiamine FT pyrophosphate enzymes, score 343.90, E-value 5e-106" FT /db_xref="GOA:O87839" FT /db_xref="HSSP:1OZG" FT /db_xref="InterPro:IPR012000" FT /db_xref="UniProtKB/TrEMBL:O87839" FT /protein_id="CAA19777.1" FT /translation="MPDDTQDVISGGHLVAKALKAEGVDRIYTLCGGHIIDIYDGCVDE FT GIEVVDVRHEQVAAHAADGYARITGKPGCAVVTAGPGTTDAVTGVANAFRAESPMLLIG FT GQGAHTQHKMGSLQDLPHVDMMTPITKFAATVPDTARAADMVSMAFRECYHGAPGPSFL FT EIPRDVLDAKVPAEKARVPRAGGYRASTRSAGDPEAVERLADLLVHAEKPAVLLGSQVW FT TTRATEAAVELVRTLNVPAYMNGAGRGTLPPGDPHHFQLSRRYAFSNADVIVIVGTPFD FT FRMGYGKRLSPDATVVQIDLDYRTVGKNRDIDLGIVGDAGLVLKSVTEAASGRINGGAA FT KRKEWLDELRAAERTALDKRLPQLRSDASPIHPYRLVSEINDFLTEDSIYIGDGGDIVT FT FSGQVVQPKSPGHWMDPGPLGTLGVGVPFVLAAKQARPDKEVVALFGDGAFSLTGWDFE FT TLVRYDLPFVGIVGNNSSMNQIRYGQAVKYGKERERVGNTLGDVPYDEFARMLGGHGEE FT VRDPADIGPALRRARESGKPSLINVWVDPDAYAPGTMNQTMYK" FT misc_feature complement(123572..125143) FT /note="Pfam match to entry PF00205 TPP_enzymes, Thiamine py FT rophosphate enzymes, score 343.90, E-value 5e-106" FT misc_feature complement(123851..123910) FT /note="PS00187 Thiamine pyrophosphate enzymes signature" FT RBS complement(125205..125208) FT /note="possible RBS upstream of SC8A6.05c" FT RBS 125331..125335 FT /note="possible RBS upstream of sucC1" FT CDS 125341..126492 FT /transl_table=11 FT /gene="SCO6585" FT /product="succinyl-coa synthetase beta chain" FT /note="SC8A6.06, sucC1, probable succinyl-coa synthetase FT beta chain, len: 383 aa; highly similar to many e.g. FT SUCC_MYCT U succinyl-coa synthetase beta chain (EC 6.2.1.5) FT (387 aa), fasta scores; opt: 901 z-score: 1682.1 E(): 0, FT 56.1% identity in 387 aa overlap. Contains Pfam match to FT entry PF00549 ligase-CoA, CoA-ligases, score 119.60, FT E-value 2.9e-32" FT /db_xref="GOA:O87840" FT /db_xref="HSSP:1JKJ" FT /db_xref="InterPro:IPR013650" FT /db_xref="UniProtKB/Swiss-Prot:O87840" FT /protein_id="CAA19778.1" FT /translation="MDLYEHQARELFKEHGIVVPRAEVTDSPERAREIARALGGRAVVK FT AQVKTGGRGKAGGVRLAADPAEAEEAARHILGMDIRGHTVDTVMLAEPCEIEREFYVSY FT VLDRASGGFLAIASAEGGTEIEEVAARRPEAVARIPVDPATGVHTATAVRIADAAGLPP FT QTVDTLVRLWKVLVREDALLVEVNPLVRTAEGRIVALDGKVTLDDNARFRQSRWGETRQ FT EDADSLEARAGAKGLNYVKLDGEVGVIGNGAGLVMSTLDVVAGCGARPANFLDIGGGAS FT ARVMADGLSVVLSDPDVRSVLVNVFGGITACDAVADGIVRALDEVRLTKPLVVRLDGNN FT AARGRALLDARAHPLVEQATTMDGAARRAARLATAASTAGQAG" FT misc_feature 126037..126384 FT /note="Pfam match to entry PF00549 ligase-CoA, CoA-ligases, FT score 119.60, E-value 2.9e-32" FT RBS 126491..126496 FT /note="possible RBS upstream of sucD1" FT CDS 126507..127433 FT /transl_table=11 FT /gene="SCO6586" FT /product="succinyl-coa synthetase alpha chain" FT /note="SC8A6.07, sucD1, probable succinyl-coa synthetase FT alpha chain, len: 308 aa; highly similar to many e.g. FT SUCD_MYC TU succinyl-coa synthetase alpha chain (EC FT 6.2.1.5) (303 aa ), fasta scores; opt: 1273 z-score: 1425.5 FT E(): 0, 64.7% identity in 300 aa overlap. Contains PS01216 FT ATP-citrate lyas e / succinyl-CoA ligases family signature FT 1, PS00399 ATP-ci trate lyase / succinyl-CoA ligases family FT active site and P fam match to entry PF00549 ligase-CoA, FT CoA-ligases, score 1 32.10, E-value 9.3e-36" FT /db_xref="GOA:O87841" FT /db_xref="HSSP:1JKJ" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:O87841" FT /protein_id="CAA19779.1" FT /translation="MAIYLTKESKVLVQGMTGAEGMKHTRRMLAAGTDVVGGVNPRKAG FT RTVDFDNRTVPVFGSVREGIERTGADVTVVFVPPAFAEAAVVEAADAGVGLAVVITEGI FT PVHDSVALTAHARAKGTRVIGPNCPGLITPGQSNAGIIPPDITKPGRIGLVSKSGTLTY FT QLMYELRDIGFSTCVGIGGDPVVGTSHIDCLAAFEDDPDTELIVLIGEIGGDAEERAAA FT HIRAHVTKPVVAYIAGFTAPEGRTMGHAGAIVSGSSGTARAKKEALESVGVRVGSTPTE FT TARHVLQALDVPGGAAPDGAARDGARA" FT misc_feature 126915..127352 FT /note="Pfam match to entry PF00549 ligase-CoA, CoA-ligases, FT score 132.10, E-value 9.3e-36" FT misc_feature 126972..127055 FT /note="PS01216 ATP-citrate lyase / succinyl-CoA ligases fam FT ily signature 1" FT misc_feature 127218..127259 FT /note="PS00399 ATP-citrate lyase / succinyl-CoA ligases fam FT ily active site" FT RBS 127419..127422 FT /note="possible RBS upstream of SC8A6.08" FT CDS 127430..128992 FT /transl_table=11 FT /gene="SCO6587" FT /product="putative dehydrogenase" FT /note="SC8A6.08, probable dehydrogenase, len: 520 aa; some FT similarity to many diverse dehydrogenases, e.g. SSDH_RAT su FT ccinate semialdehyde dehydrogenase (488 aa), fasta scores; FT opt: 308 z-score: 301.8 E(): 1.4e-09, 26.0% identity in 439 FT aa overlap" FT /db_xref="GOA:O87842" FT /db_xref="InterPro:IPR016162" FT /db_xref="UniProtKB/TrEMBL:O87842" FT /protein_id="CAA19780.1" FT /translation="MTAAGAPDTQPLTLKSGTSWADSWRRCRTAAPEAFRDDRVLNLWD FT AGWRADGRVLPATSPVDGTPIAGPPRIDAATAHRAVRASLDQHRAWRHVPLPERRARVA FT ATLDALAQHRELLALLLVWEIGKPWRSARADVDRAVDGVRWYLDGIEDMLDGRAPLDGP FT VSNIASWNYPMSVLVHALLVQALAGNAVIAKTPTDGGVACLTLACALAAREGLPVTLLS FT GGGRELSQALVRAPEIGCVSFVGGRDTGADVATALADLGKRHILEQEGLNTWGIWNFTD FT WDALTRTVPKLFDYAKQRCTAYPRFVVQRQRFDAFLAAYLPAVRTLRVGHPLAVAAPDD FT PYPALDFGPVINAAKAKELHDQVAEAVDRGAVPLHRGSAADARFLPGQDTSAYVQPVTL FT LNPPRSSPLHHAEPFGPVDTIVLVDTEAELLAAMNASNGALVATLSTDDPATYDRLAPQ FT IRAFKVGHGVPRSRGDRDELFGGHGGSWRGAFVGGELLVRAVTRGPAGERLPGNFPDHH FT LMP" FT repeat_region 128981..129072 FT /note="4x 23 bp degenerate repeats" FT CDS complement(129120..130451) FT /transl_table=11 FT /gene="SCO6588" FT /product="conserved hypothetical protein" FT /note="SC8A6.09c, unknown, len: 443 aa; some similarity to FT M. tuberculosis hypothetical protein Y029_MYCTU MTCY373.09 FT C (521 aa), fasta scores; opt: 371 z-score: 502.3 E(): 9.7e FT -21, 28.3% identity in 446 aa overlap" FT /db_xref="InterPro:IPR018723" FT /db_xref="UniProtKB/TrEMBL:O87843" FT /protein_id="CAA19781.1" FT /translation="MSDWMVTQGPLPRRRPRVLSPLREHLRDTFWFAPTAAMAGVLVVW FT LVAQELDAALVRSLQDDGDYDTLAELLRFADDAKTVVSAVGSAMMTFIGVVFSISLVAV FT QMASGQFTPRVVRLFVRSRITKATFAVFLATFVLTLLVLTSYDSNPDPRAATSVPLVQS FT VLTLVMVALSLLLFVMYVNATLRLMRVSHVIARIAAESFRVAALMPVPAHGGEAPGLGP FT VTAWIAHDGQGGVLRDVHIARLVRVARGHGVVLRLVPRIGDFLVPGTPVLAVHGGAAPP FT RRALRYALSVGVERTFHQDLAFGLRQLSDIGLRALSPAVNDPTTAVQALDRVVQILATL FT SRRPLDAAVHRDRRGALRLVQPVPGWAELVDLGFAEVRACATGSPQVTRRLMAGLDDLL FT LLVPPERRAPLLRHRELLRQAVERTAPTAAERVFALRPDRQGIG" FT tRNA 130604..130688 FT /note="tRNA Leu; anticodon GAG" FT CDS 131063..133123 FT /transl_table=11 FT /gene="SCO6589" FT /gene_synonym="fusB" FT /product="elongation factor G" FT /note="SC8A6.10, fusB, possible alternative elongation fact FT or G, len: 686 aa; highly similar to many e.g. EFG_BACSU el FT ongation factor g (ef-g) (691 aa), fasta scores; opt: 2058 FT z-score: 2027.9 E(): 0, 47.5% identity in 692 aa overlap. A FT lso 46% identical to S. coelicolor fusA EFG_STRCO (fragment FT ) (93 aa). Contains PS00017 ATP/GTP-binding site motif A (P FT -loop), PS00301 GTP-binding elongation factors signature an FT d Pfam matches to entry PF00009 GTP_EFTU, Elongation factor FT Tu family, score 521.10, E-value 7.8e-153 and Pfam match t FT o entry PF00679 EFG_C, Elongation factor G C-terminus, scor FT e 214.30, E-value 1.8e-60" FT /db_xref="GOA:O87844" FT /db_xref="HSSP:2EFG" FT /db_xref="InterPro:IPR004161" FT /db_xref="UniProtKB/Swiss-Prot:O87844" FT /protein_id="CAA19782.1" FT /translation="MRTNPLTTVRNLGILAHVDAGKTTVTERILYLTGTTHKRGEVHDG FT TTVTDFDPQERDRGITIFAAAVSCAWAGHRINLIDTPGHVDFADEVERSLRVLDGAVAV FT FDAVAGVEPQSESVWRQADRHGVPRIAFVNKMDRAGADLDAAVASIRERLHPVPLVVQL FT PIGTEDGFTGVVDLPRMRALVWADGADAAEEGPVPGTLREEAARRRRVLEEAVAERHPG FT ALEEFCDRETLTAATLTGALRDLTRTGDGVVVLCGSAYRNRGVEPLLDAVVAYLPSPLD FT VPPVRGTHDGAERERPADPAAPMAALAFKVNATPTGRLTYLRVYSGTIGKGDTVWDAGT FT RRTERIGRILRVRADRHDPLERAVAGDIVAVVGLKTARAGSTLCAPGAPLLLEPPGVAE FT PVVHVAVEARRSTETDRLAAALARLTEEDPSLALRTDPETAQTVLSGMGELHLEVAVER FT VRREYGLEVTVGRPGVAYRETVGEGVTGFVHRHVKQDGGAGQFAHIVLDVEPWEQDADG FT DGAGGGFVFRSTVVGGRVPQEYVRAVEAGCRDALAEGPLGGHPVTGLRVTLTDGRTHVK FT DSSDTAFRTAGRFGLRDALRASGMILLEPVVEVTVTVPEDGVGGVLGDLAARRGRVTGS FT DPRGGAVVVTATVPLAELFGYATRLRSRTQGRGTFTARPTGYAQAPAAVVR" FT misc_feature 131081..132505 FT /note="Pfam match to entry PF00009 GTP_EFTU, Elongation fac FT tor Tu family (contains ATP/GTP binding P-loop), score 521. FT 10, E-value 7.8e-153" FT misc_feature 131108..131131 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 131210..131257 FT /note="PS00301 GTP-binding elongation factors signature" FT misc_feature 132578..133114 FT /note="Pfam match to entry PF00679 EFG_C, Elongation factor FT G C-terminus, score 214.30, E-value 1.8e-60" FT stem_loop 133161..133203 FT /note="hairpin loop with 18/19 bp stem" FT stem_loop 133249..133288 FT /note="hairpin loop with 18 bp stem" FT CDS complement(133361..135568) FT /transl_table=11 FT /gene="SCO6590" FT /product="putative secreted esterase" FT /note="SC8A6.11c, probable secreted esterase, len: 735 aa; FT similar to TR:Q54345 (EMBL:Z50108) esterase precursor from FT Streptomyces lividans (509 aa), fasta scores; opt: 553 z-sc FT ore: 526.3 E(): 4.5e-22, 38.2% identity in 403 aa overlap a FT nd to other membres of the trypsin family. Contains probabl FT e N-terminal signal sequence and Pfam match to entry PF0008 FT 9 trypsin, Trypsin, score 31.60, E-value 4.4e-07" FT /db_xref="GOA:O87845" FT /db_xref="HSSP:1L5G" FT /db_xref="InterPro:IPR001254" FT /db_xref="UniProtKB/TrEMBL:O87845" FT /protein_id="CAA19783.1" FT /translation="MSSIRRSRSAVLGAVLTAGSLALSTAAAVAVTGGTPVADSDTTHA FT YTAQITVGAHDRGCSAVLVDAEWLLTAASCFAEDPAASLAVPAGVPAKATTAVIGRSDL FT SGTQGAERRVVEIVPRTDRDVVLARLNRPVTNVTPAQLATTAPTAGAELTFAGYGRTDT FT VWAPLQLHTGTYTVDSTAATSAGVTGKDGAAACMGDTGGPVVSGGKLVGLNSQSFQGGC FT LGVDETQTSTAGVIARVDDLASWIDEKAGATRIVDFNGDAVEDIAIGDPMATVGGDTTA FT GLVRVVHGGGKGVAEITQDLDWVTGGAEAGDHFGNHLATVDYNEDGYTDLVVTASEENV FT GSAVDAGFFDILFGGKNGLGSGPASRHFEQGSGNGSIGSAAPETGDRMGASLAAGTTAA FT GEPWILVGAPGEALGSLTKAGGAFYVHGDTSISINQDSSNVPGAAEANDAFGTSVTGDS FT NFIAIGAPGDAIGGDANAGNLAVLSHKLDADGRPTVVAGMDQDNEKISGSAEAGDKFGQ FT ALALVAYRPSGAATATDSILAIGSPGEALAAETGGEQRAGAGNVMLVHLAADGSWDYLH FT ALNQGSSTDDRSGTIEAGDSVGASLSAVNTAPRAVGSADTLKVAVGAPGEDLAGAADAG FT AIHTFSLMGSAGANDLWIEAGDGDGVPGTPGAGEKLGTSIHFTPRNLYAGMPYGPAATG FT ALHVLPYPNVVPGGTSRPATTYQPGQGGLPANGNYFGYAAR" FT misc_feature complement(134831..135478) FT /note="Pfam match to entry PF00089 trypsin, Trypsin, score FT 31.60, E-value 4.4e-07" FT RBS complement(135579..135582) FT /note="possible RBS upstream of SC8A6.11c" FT CDS complement(135602..136108) FT /transl_table=11 FT /gene="SCO6591" FT /product="putative secreted protein" FT /note="SC8A6.12c, possible secreted protein, len: 168 aa; c FT ontains possible N-terminal signal sequence" FT /db_xref="UniProtKB/TrEMBL:O87846" FT /protein_id="CAA19784.1" FT /translation="MKKRSSFVRVLGAAATAGALAWAVLAQGNAGAAPTTATEAVADAA FT PGYAVEDYNYPNADKILAEQNIVLKRGDGHIVLADCAGGDNLLQFLARDHEDVCFEVTA FT DEGYLTLELPAVHGVKTDDSVNTHLEMTAEDDQVEYDIPADTWKGVGESVDGREHVLVE FT IRVTN" FT RBS complement(136114..136117) FT /note="possible RBS upstream of SC8A6.12c" FT CDS complement(136230..136619) FT /transl_table=11 FT /gene="SCO6592" FT /product="putative secreted protein" FT /note="SC8A6.13c, probable secreted protein, len: 129 aa; c FT ontains N-terminal signal sequence and appropriately positi FT oned PS00013 Prokaryotic membrane lipoprotein lipid attachm FT ent site" FT /db_xref="UniProtKB/TrEMBL:O87847" FT /protein_id="CAA19785.1" FT /translation="MTRKRAGGRWFFAVLAASAVLVSGCSGSVDPKKLPGVYRNDEGGQ FT IELSADGTFSAERVTTNESAGPVDFSGSWDYQDPDTSSDFVYLGVEDGGLGKTGGIQLY FT VDDQDTLYFQSDPDGPVTQKLNKTS" FT misc_feature complement(136545..136577) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid attac FT hment site" FT CDS complement(136616..140059) FT /transl_table=11 FT /gene="SCO6593" FT /product="hypothetical protein" FT /note="SC8A6.14c, unknown, len: 1147 aa; contains two FT Ala-rich domains, PS00017 ATP/GTP-binding site motif A FT (P-loop) and probable coiled-coil regions from 238 to 292, FT 399 to 441, 445 to 488, 490 to 573, 786 to 820, and 829 to FT 871" FT /db_xref="InterPro:IPR005506" FT /db_xref="UniProtKB/TrEMBL:O87848" FT /protein_id="CAA19786.1" FT /translation="MPLGVFGSGPAYAADTAETDGGTGLPDTDRGKVVQAYRTGGRAVR FT TAAAAALVGNADSVATFLGERLPTATAEDNRFTLTEALVSAGKATRTGIGQALSGGDAA FT VAAYLQGGFESAVHEDLQVAVTTVNAHGGKAVKRESSEALATGTDFALRDFLSSGQYQA FT HDEDQRVEVTSILVTASPQVREYAERALDDGSPRAIRWFLTTGQYIARARDEESAEIQQ FT LVKIVESEGRRAELKTDEAVELSEQAVQAAAKAKAAALEAKAEAQAAEQDVQRSARAAN FT KAARAAQGAAAAASTAVSASRTAQAAARRSVTAANAAAAAAAAAGRAASRAYRAAISAS FT KNANMAEAANQAAKAARVMVDWVRTVAAKAKLAALASDAAEAAGNAAAGAAVDSAAAAR FT ASADAAAASGAAQSQAAEAQRQAAIAEAAAGRATAAASRASTLSRRSAAAARSASAAAD FT SAADHAEKAADAAEEAARNAGKAVDYANRSTAAANAAVEAANKAYDAVTEAREVEKEAR FT EAEIARLNEETEEAIEVAKQQRREETDRLERANRERTQESRLSEELVALITAMEAAFAD FT GRTGEAVDKGRQAAVLLLDRSGTWTREAAEFALAGSDEDVLRWIEADRVIALQQDNAEN FT TAATAAISTQNVAEAAAAALRTEDPAAIRTFLEKGAVEAARDDNEVEVTTLLADDSTGT FT AVRRAAEAALTDGSAEALHTFLHVKRAAAVHEDDKVAATTLLVSGGPYVQAAAKVALEG FT DTHMLRQFIGTTQHEFARIDHDHATHISAIRAAIARAAKTAQDALEDAARASEAAAVAR FT QAAAEATEWAGKAEGWAADAKASAEEARQNAEDAENSAAAAARSAQTAANAAAAARRAS FT SVARDAANRAVRSAETAASYALDAQRSATVARQAKLAAGKSFAEAAAAATEARILVIQA FT AIRQAIQDALDNSKVPIDGETGLPDGAESCLTPFGDPIEHRNNTNPWELGWSWLTGSGP FT TSQCFGPDDEFTRLYREHSHTQGVLAYFLNEWQRTGKYELGHTYMNDYMLSGFDGAGKY FT MTDYGTLTTGGLTGNLAYTFLGSHQVRMTPIRENADGSVTWRYTAYNESDIESATHPPV FT IGYTDWWSDTVGAFVDKVVGDEGPLSPKTQVIEFDVTLGP" FT misc_feature complement(137324..137347) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(140066..140069) FT /note="possible RBS upstream of SC8A6.14c" FT CDS complement(140408..142216) FT /transl_table=11 FT /gene="SCO6594" FT /product="putative secreted protein" FT /note="SC8A6.15c, probable secreted protein, len: 602 aa; c FT ontains probable N-terminal signal sequence" FT /db_xref="InterPro:IPR017909" FT /db_xref="UniProtKB/TrEMBL:O87849" FT /protein_id="CAA19787.1" FT /translation="MPSSPTPSPTPSGAPEPSGVRRRSLLAAAAAAPVLASLAGAGTAA FT ADSPGGPRALPGGGDLGPNVIVFDPSTANIQGRLDEIFKQQESAQFGTGRYALLFKPGT FT YNGLNAQLGFYTSIAGLGLSPDDTTINGDVTVDAGWFDGNATQNFWRSAENLALVPVSG FT TNRWAVSQAAPFRRMHVRGDLNLAPDGYGWASGGYIADSRIDGTVGPYSQQQWYTRDSS FT VGGWLNAVWNMVFSGVEGAPAQSFPEPPYTTLETTPVSREKPFLYLDGDEYRVFLPEKR FT TDARGVSWGSGTPRGTSLPLSRFYVARPDDSAATLNQALEEGLHLLLTPGVYRLDRTVD FT VQRAGTVVLGLGYATLIPDNGVTALKVADVDGVRLAGFLVDAGPVNSATLLEVGPEGAS FT ADHSANPTTVQDVFVRIGGAGPGKATTSLVVNSRHTIVDHTWVWRADHGDGVGWETNRA FT DYGVVVNGDDVLITGLFVEHFNKYDVQWNGERGRTVFFQNEKAYDAPDQAAIQNGSVKG FT YAAYRVGDDVTEHEGWGLGSYCYYNVNPSIVQHHGFAAPNRSGVRFHGLLVVSLGGNGQ FT YECVINDTGSPTSGTDTVPSKVVQYP" FT RBS complement(142227..142232) FT /note="possible RBS upstream of SC8A6.15c" FT RBS 142472..142478 FT /note="possible RBS upstream of SC8A6.16" FT CDS 142483..143565 FT /transl_table=11 FT /gene="SCO6595" FT /product="putative secreted protein" FT /note="SC8A6.16, probable secreted protein, len: 380 aa; co FT ntains N-terminal signal sequence and TTA Leu codon, possib FT le target for action of bldA" FT /db_xref="InterPro:IPR018535" FT /db_xref="UniProtKB/TrEMBL:O87850" FT /protein_id="CAA19788.1" FT /translation="MPRRSKVLSGTLVASALLLTSIGIGTVAANADTPAASAPARAAHS FT GHTMAVSTAASPEDPDGDGYIPANPPVTGVTPSTKEPPHRYFHEFQANCGVSHTAPDDP FT IVYAQQPGKSHDHTFMGNTTTDAYSTTASLDAGSTTCLAPGDRSGYWMPTMYDGDRPVL FT PVGPQTIYYKAGVTDYTSVRPFPKGLRYVVASPMQSAQEFRDHPGFVEGWECGDSFFNV FT DFPTDCPERQDVQVNIRFQAPSCWDGRNLDTPDHKSHMAYPVVNPGTNNNICPADHPVA FT LPMIEFKMAFPVNGDLSRLRLASGASYSFHYDFFNAWDEATLDAMVGHCIVGGLQCDAR FT GYDQTHPEAGAALNEDYELP" FT misc_feature 142531..142533 FT /note="TTA Leu codon, possible target for action of bldA" FT RBS 143646..143649 FT /note="possible RBS upstream of SC8A6.17" FT CDS 143660..145429 FT /transl_table=11 FT /gene="SCO6596" FT /product="putative secreted protein" FT /note="SC8A6.17, probable secreted protein, len: 589 aa; co FT ntains N-terminal signal sequence and PS00213 Lipocalin sig FT nature" FT /db_xref="GOA:O87851" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:O87851" FT /protein_id="CAA19789.1" FT /translation="MSRPRTPTSRLTPARRLTAPLTAGLLTLGALTALPAAQAHAAGSV FT VKVTGGQGDWQLTVDGSPYTVKGLTWGPSPADADRYLPDLASMGVNTIRTWGTDASSRP FT LLDSAAAHGVKVIAGFWLQPGGGPGSGGCVNYLTDTAYKDQMLAEFPRWVQEYKDHPGV FT LMWNVGNESVLGLQNCYGGDELERQRDAYTTFVNDVAKKIHAVDPNHPVTSTDAWVGAW FT PYYQKNAPDLDLYAVNSYDAVCDVRSAWEQGGYTKPYIVTESGPAGEWEVPDDANGVPE FT EPTDRAKAQGYTDAWNCVTGHRGVALGATLFHYGTEYDFGGIWFNLLPAGQKRLSYYAV FT KRAYGGDTSHDNTPPVVSGFGVEGDAGKVQAGKDLVLTVRATDPDGDPIAYEVLANSNY FT IDQSKQLTPLPVTDLGGGRLKVTAPERPGVWKLYVKATDGRGNVGVETLSARVVPPAVD FT GTNVALGKPVTASSFQPSYGDCPCTAANAVDGNPVTRWASDWSDPQWLQVDLGTRTGFR FT HVQLYWESSYAKAYTVQTSDDGQNWRTVSAVTDGNGGVDTLDVSGTGRYVRVNGTARGT FT GYGYSLYEFGVYA" FT misc_feature 144602..144640 FT /note="PS00213 Lipocalin signature" FT RBS 145446..145452 FT /note="possible RBS upstream of SC8A6.18" FT CDS 145461..148040 FT /transl_table=11 FT /gene="SCO6597" FT /product="putative beta-glucosidase" FT /note="SC8A6.18, probable beta-glucosidase, len: 859 aa; si FT milar to many e.g. BGLS_AGRTU beta-glucosidase (EC 3.2.1.21 FT ) (818 aa), fasta scores; opt: 810 z-score: 1139.9 E(): 0, FT 37.2% identity in 862 aa overlap" FT /db_xref="GOA:O87852" FT /db_xref="InterPro:IPR001764" FT /db_xref="UniProtKB/TrEMBL:O87852" FT /protein_id="CAA19790.1" FT /translation="MGTSDEEIDRLLGKLTPRARALLLNGATTWRTRAEPAVELRELVM FT SDGPAGVRGEAWDERSTSLLLPSASALAATWDEALVEDLGGLLAAEARRKGVDVLLAPT FT LNLHRSPLGGRHFECLSEDPELTGRIGAALVRGIQAHGVAATAKHYVANDSETDRLTVD FT VRVGERALREVYLAPFEAAVAAGVRLVMAGYNAVNGTTMTANALLTDPLKSEWGFDGVV FT VSDWGAVRGTTGTARAGLDLAMPGPDGPWGEALARAVAEGAVPEPAVDDKARRLLRLAA FT WLGALGGRDVSRSPVPGRPADSPGAEGADGGAGAGPSSGAEGLPGRGPAHGAKPSGPRP FT RRAGDGRALARRAVAAGAVLLANKDVLPLDPEHLGTVAVIGAHAARTRTQGGGSAGVFP FT RGEVSVLDGIRAELRGRARVVHVPGPRPDGPAPPLDPDTCTDPRSGLPGVLLRMLDADG FT RELYAERRRGGRLLEPRLVPGAHTVEIRARLCPRTGGSWSLGVAGFGRMSLTTDGRTLL FT EGDFPPSTDDPAVMHVNPPAQYATADLTAGRDTLLVARRELAPGTGRATVLVAAPPAPD FT VTASLAEAVRAAGAADAAVVVVGTTEHGESEGYDRTDLALGATQDALVRAVAAANPRTV FT AVVNSGGPVELPWREQAGAVLLAWFPGQEGGGGLADVLFGHAEPGGRLPTTWPAVLADA FT PVTRTRPDGGRLDYDEGLHLGHRGWLRHHRTPAYWFGHGLGYTTWRYEELTVPPVTRAG FT DGLTVRVRVRNTGARAGREVVQVYLARPASALDRPARWLAGYTAVRARPGETVTATVRV FT PARALRHWSVAEHAWRTEAGPCRVLAGRSAGDVPLAAEVEVVPTASA" FT CDS 148137..149177 FT /transl_table=11 FT /gene="SCO6598" FT /gene_synonym="SC8A6.19" FT /product="transcriptional regulator" FT /note="SC8A6.19, probable transcriptional regulator, len: FT 246 aa; similar to many members of the lacI family, e.g. FT CCP A_BACSU glucose-resistance amylase regulator (334 aa), FT fast a scores; opt: 313 z-score: 569.6 E(): 1.7e-24, 31.2% FT identity in 317 aa overlap. Contains PS00356 Bacterial FT regulatory proteins, lacI family signature, helix-tur-helix FT motif at aa 7-28 (Score 2389, +7.32 SD) and Pfam matches to FT entry P F00532 Peripla_BP_like, Periplasmic binding FT proteins and LacI family, score 86.50, E-value 5.3e-22 and FT Pfam match to entry PF00356 lacI, Bacterial regulatory FT proteins, lacI family, score 43.00, E-value 1e-10" FT /db_xref="GOA:O87853" FT /db_xref="HSSP:1LQC" FT /db_xref="InterPro:IPR001761" FT /db_xref="UniProtKB/TrEMBL:O87853" FT /protein_id="CAA19791.1" FT /translation="MSRQAPTLEDVAREAGVSRATVSRVVNGVRNVDPAIQDLVRRAIE FT RTGYAPNQAARQLVTRRTTTVALVVSGAGDATDTEQNAFATRVFADPFFGRVVGGVVGH FT LRPRRMHPVLMFAETPEARQEVVAYLRQGGADGALVVSTHPDDPLPALLAGAGLPAVLF FT ARPGRPVPLSYVDLAHREGGRLAAEHLLERGCRRIATVAGPLAVAASQERLAGFRDTLA FT RHGHPYVPVAEGGFTVDSGMAAMTSLLAEHPDTDGVFTANDLMAQGAVQVLRDHGRRVP FT QDVAVVGFDDSSVAVTCRPRLTTVRQPVEEMAATMARLLDDHIKGARGEPTSVVFDPEL FT VVRESA" FT misc_feature 148146..148229 FT /note="Pfam match to entry PF00356 lacI, Bacterial regulato FT ry proteins, lacI family, score 43.00, E-value 1e-10" FT misc_feature 148158..148214 FT /note="PS00356 Bacterial regulatory proteins, lacI family s FT ignature" FT misc_feature 148368..149087 FT /note="Pfam match to entry PF00532 Peripla_BP_like, Peripla FT smic binding proteins and LacI family., score 86.50, E-valu FT e 5.3e-22" FT CDS complement(149193..149846) FT /transl_table=11 FT /gene="SCO6599" FT /gene_synonym="SC8A6.20c" FT /product="putative transcriptional regulator" FT /note="SC8A6.20c, probable transcriptional regulator, len: FT 217 aa; some similarity to members of the tetR family e.g. FT TER4_ECOLI tetracycline repressor protein class D (217 aa), FT fasta scores; opt: 158 z-score: 233.4 E(): 9.2e-06, 35.2% FT identity in 88 aa overlap. Contains probable FT helix-turn-helix motif at aa 29-50 (Score 1279, +3.54 SD) FT and Pfam match to entry PF00440 tetR, Bacterial regulatory FT proteins, tetR family, score 31.90, E-value 4.2e-07" FT /db_xref="GOA:O87854" FT /db_xref="InterPro:IPR001647" FT /db_xref="PDB:2HXI" FT /db_xref="UniProtKB/TrEMBL:O87854" FT /protein_id="CAA19792.1" FT /translation="MAGRRRWSTEQILDAAAELLLAGDAETFSVRKLAASLGTDSSSLY FT RHFRNKTELLRAVADRILLSAMDGYRPEGDWKQRLTAVALRLRESFGQQPQLAAVWGRH FT GSGGTGSRLMMEEVLQALRASGLPDDEIPARYHRLVILISSLITAEGGFGAVGAQEHEQ FT GMEQFRVAVLGADPERFPALSHFAREIRPLGADRGAAFEEILAAHLAHLEAAAP" FT misc_feature complement(149673..149813) FT /note="Pfam match to entry PF00440 tetR, Bacterial regulato FT ry proteins, tetR family, score 31.90, E-value 4.2e-07" FT RBS complement(149856..149859) FT /note="possible RBS upstream of SC8A6.20c" FT CDS complement(150012..151337) FT /transl_table=11 FT /gene="SCO6600" FT /gene_synonym="SC8A6.21c" FT /product="putative transcriptional regulator" FT /note="SC8A6.21c, probable transcriptional regulator, len: FT 441 aa; some similarity to members of the ROK family e.g. FT XYLR_ANATH xylose repressor (399 aa), fasta scores; opt: FT 365 z-score: 361.7 E(): 6.6e-13, 27.2% identity in 397 aa FT over lap. Contains Pfam match to entry PF00480 ROK, ROK FT family, score 38.10, E-value 3e-10" FT /db_xref="InterPro:IPR000600" FT /db_xref="UniProtKB/TrEMBL:O87855" FT /protein_id="CAA19793.1" FT /translation="MARHGGRTVRDLRRESRSTVLQRLYFDGPMSRLALGSAAGLSSGS FT VSNVVAELMADGLVEEAGTLGADGGRPRTLVRVAADRGRLVGVDVGETRVRVELFDLSM FT SELARTERVLPGHGSRSYDVGVVAGHILDGVAEVLGADRADGRAQGRGELLGVGIGVPG FT IVEHTADGTLVHGQTVGWDAVPLEALLRDSGRLPAHVPLFVENGARTLGQAEMWFGGGR FT GARNAVVVLFGSGVGACVVTDEVEQGRAVEWGHLTVRVRGRRCRCGARGCLEAYAGAEA FT LLARWREAGGQPPSGADEEAALTALLSAARPGDGGEPDPVAAEVLAETAEYLGAGLADL FT VNLFQPERVLVGGWAGLQLGPAFLESVRAHTLAHALRHPAGRVGIALGRLGPDAVTVGA FT AILPLAAFFARGGRRPPVDSPAPAPAWRAALGGRLAARRGGG" FT misc_feature complement(150492..150740) FT /note="Pfam match to entry PF00480 ROK, ROK family, score 3 FT 8.10, E-value 3e-10" FT RBS complement(151344..151348) FT /note="possible RBS upstream of SC1A6.21c" FT RBS 151506..151510 FT /note="possible RBS upstream of SC8A6.22" FT CDS 151513..152829 FT /transl_table=11 FT /gene="SCO6601" FT /product="putative secreted sugar binding protein" FT /note="SC8A6.22, probable secreted sugar binding protein, l FT en: 438 aa; similar to e.g. S. coelicolor TR:P72397 (EMBL:Y FT 07706) putative maltose-binding pootein malE (423 aa), fast FT a scores; opt: 425 z-score: 307.7 E(): 6.7e-10, 28.9% ident FT ity in 439 aa overlap. Contains N-terminal signal sequence FT and appropriately positioned PS00013 Prokaryotic membrane l FT ipoprotein lipid attachment site" FT /db_xref="GOA:O87856" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:O87856" FT /protein_id="CAA19794.1" FT /translation="MRSIRAAAVGAVTMSLALAATACGGGSSSGGGSNDSPKELTYWAS FT NQGASVEVDKKVLQPELDKFEKETGIKVKLEVVPWSDLLNRILTATTSGQGPDVLNIGN FT TWSASLQATGALLPWDAKNFEKIGGRDRFVDSALGSTGVEGQDPAAVPLYSMAYALYYN FT KQMFADAGITKPPATWDELVETGRKISRDGKWGLGAEGSNLSNNIHQVFVLAKQHGADF FT FTADGKPDFTSDGAVAAVKQYVDLMAQDKVVAPGNAEYAQNQSLSDFAKGKTAMVLWQT FT ASATFKTMGMKDDEWGVAPAPVPSGAPGAGKATNSMVAGINMAVFKNSDNLDGATKFVK FT FMTSDAEQKLLNKAYGSIPPVKAAQSDPAFNTQATAVLRETLATSAAALPQVPDESQFE FT TAVGTAVKELFADAANGREVTTGSVKEKLAKAQQQMPSK" FT misc_feature 151549..151581 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid attac FT hment site" FT CDS 152891..153919 FT /transl_table=11 FT /gene="SCO6602" FT /product="putative transmembrane sugar transport protein" FT /note="SC8A6.23, probable transmembrane sugar transport pro FT tein, len: 342 aa; similar to e.g. S. coelicolor TR:P72398 FT (EMBL:Y07706) putative maltose permease malF (334 aa), fast FT a scores; opt: 494 z-score: 521.6 E(): 8.2e-22, 32.6% ident FT ity in 322 aa overlap. Contains PS00017 ATP/GTP-binding sit FT e motif A (P-loop), PS00402 Binding-protein-dependent trans FT port systems inner membrane comp signature and Pfam match t FT o entry PF00528 BPD_transp, Binding-protein-dependent trans FT port systems inner membrane component, score 42.00, E-value FT 1.3e-08" FT /db_xref="GOA:O87857" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:O87857" FT /protein_id="CAA19795.1" FT /translation="MTTTTASAQPGERTVGKSSPGTARGPRRRPGRIRRIGLPYLLLLP FT ALLLELLVHLVPMVIGIVMSFKELTQFYIRDWTTAPWAGLDNFTMSVDFDAPVGEALLH FT SFLVTCAFTILSVGLCWLIGTAAAICMQDAFRGRGLLRAIFLVPYALPVYAAVITWAFM FT FQHDNGLVNHVLHDQLGLTDKPSFWLIGDNSFVALLVVSVWKGWPFAFLIVMAGLQNIP FT KELYEAAALDGAGVWQQIRRITLPSLRPVNQVLVLVLFLWTFNDFNTPFVLFGKAAPEA FT ADLISIHIYQSSFVTWNFGAGSAMSVLLLLFLLLVTGVYLFVTSRTARAPRNSRERKTA FT DV" FT misc_feature 152921..152944 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 153539..153778 FT /note="Pfam match to entry PF00528 BPD_transp, Binding-prot FT ein-dependent transport systems inner membrane component, s FT core 42.00, E-value 1.3e-08" FT misc_feature 153542..153628 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp signature" FT CDS 153927..154766 FT /transl_table=11 FT /gene="SCO6603" FT /product="putative transmembrane sugar transport protein" FT /note="SC8A6.24, probable transmembrane sugar transport pro FT tein, len: 279 aa; similar to e.g. S. coelicolor TR:P72399 FT (EMBL:Y07706) putative maltose permease malG (302 aa), fast FT a scores; opt: 542 z-score: 755.1 E(): 0, 36.7% identity in FT 270 aa overlap. Contains PS00402 Binding-protein-dependent FT transport systems inner membrane comp signature and Pfam m FT atch to entry PF00528 BPD_transp, Binding-protein-dependent FT transport systems inner membrane component, score 75.20, E FT -value 1.3e-18" FT /db_xref="GOA:O87858" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:O87858" FT /protein_id="CAA19796.1" FT /translation="MAAPRSFTWTRRVFLTLLTGFVLLPVYVMVSSSLKPLEDVSSQFH FT WLPSNLTIRPYIDIWSTVPLAKYFVNSLIVAGAATVCSVVIAVFAAYAVSRYEFRGKRV FT FSVTVLSTQMFPGILFLLPLFLIYVNIGNATGIALFGSRGGLILTYLTFSLPFSIWMLI FT GYFDSVPRDLDEAALVDGCGPLRALFKVVVPAAIPGIVAVAVYAFMTAWGEVLFASVMT FT NDATRTLAVGLQGYSTQNDVYWNQIMAASLVVSVPVVAGFLLLQRYLVAGLTAGAVK" FT misc_feature 154419..154646 FT /note="Pfam match to entry PF00528 BPD_transp, Binding-prot FT ein-dependent transport systems inner membrane component, s FT core 75.20, E-value 1.3e-18" FT misc_feature 154422..154508 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp signature" FT RBS 154752..154755 FT /note="possible RBS upstream of SC8A6.25" FT CDS 154763..156169 FT /transl_table=11 FT /gene="SCO6604" FT /gene_synonym="SC1F2.01" FT /product="putative beta-glucosidase" FT /note="SC1F2.01, probable beta-glucosidase, partial CDS, FT len >311 aa; similar to mnay e.g. BGLS_AGRSP FT beta-glucosidase (EC 3.2.1.21) (459 aa), fasta scores; opt: FT 784 z-score: 986.7 E(): 0, 42.5% identity in 315 aa FT overlap. Overlaps and extends SC8A6.25. Contains Pfam match FT to entry PF00232 glycosyl_hydro1, Glycosyl hydrolases FT family 1, score 350.20, E-value 2.2e-101" FT /note="SC8A6.25, probable beta-glucosidase, partial CDS, le FT n >190 aa; highly similar to many e.g. BGLA_BACCI FT beta-glucosidase (EC 3.2.1.21) (449 aa), fasta scores; opt: FT 752 z-sc ore: 1084.7 E(): 0, 59.9% identity in 167 aa FT overlap. Conta ins PS00653 Glycosyl hydrolases family 1 FT N-terminal signatu re and Pfam match to entry PF00232 FT glycosyl_hydro1, Glycosy l hydrolases family 1, score FT 348.50, E-value 7.3e-101" FT /db_xref="GOA:Q8CJM3" FT /db_xref="HSSP:1GON" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:Q8CJM3" FT /protein_id="CAD55382.1" FT /translation="MTGTPQRSHPQPERTFVTIDFAALPDDFLWGTATSAYQIEGAVAE FT DGRSPSIWDTFSHTPGKIDNGDHGDVACDHYHRTHEDIELMRRLGTNAYRLSVAWPRVV FT PGGDGPVNAKGLAFYDRLVDDLLAAGITPSVTLYHWDLPQVLQDRGGWPERDTAEHFAA FT YAAVVAERLGDRVAHWATLNEPLCSAWIGHLEGKMAPGQTDLTAAVRASYHLLLGHGLA FT MQAIRAAAPDAQVGIVNNLSTIHAATDREEDLAAARRMDGHTNRWWLDPVHGRGFPQDM FT REVYGVELPERPGDMRLIGAELDWLGLNYYFPQTVAADPTGPAPQVRTVRRAGVPRTGM FT DWEIDAGGIEELLLRLTEEYGPRKLYVTENGSSFPDLVRPDGSVDDPERQEYLTAHLAA FT CASAARKGAPLAGYFAWSLLDNFEWAYGYDKRFGLVHVDYATQVRTIKGSGHHYADIIG FT RARGRERKAA" FT misc_feature 154826..155332 FT /note="Pfam match to entry PF00232 glycosyl_hydro1, Glycosy FT l hydrolases family 1, score 348.50, E-value 7.3e-101" FT misc_feature 154844..154888 FT /note="PS00653 Glycosyl hydrolases family 1 N-terminal sign FT ature" FT misc_feature 155234..156160 FT /note="Pfam match to entry PF00232 glycosyl_hydro1, FT Glycosyl hydrolases family 1, score 350.20, E-value FT 2.2e-101" FT CDS 156284..156469 FT /pseudo FT /transl_table=11 FT /gene="SCO6605" FT /note="SC1F2.02, probable beta-glucanase pseudogene FT fragment, len: 61 aa; this appears to be a gene remnant FT similar to part of e.g. TR:O68641 (EMBL:AF052745) FT beta-1,3-glucanase II from Oerskovia xanthineolytica (435 FT aa), fasta scores; opt: 100 z-score: 207.7 E(): 0.00025, FT 38.3% identity in 60 aa overlap. There is no start codon" FT CDS complement(156508..157410) FT /transl_table=11 FT /gene="SCO6606" FT /gene_synonym="SC1F2.03c" FT /product="conserved hypothetical protein SC1F2.03c" FT /note="SC1F2.03c, unknown, len: 300 aa; similar to upstream FT gene SC1F3.04, E(): 0, 48.8% identity in 260 aa overlap FT anbd to TR:Q9L173 (EMBL:AL158057) Streptomyces coelicolor FT hypothetical protein SC10G8.32c, 263 aa; fasta scores: opt: FT 791 Z-score: 879.8 E(): 2.3e-41; 49.237% identity in 262 aa FT overlap" FT /db_xref="InterPro:IPR006764" FT /db_xref="UniProtKB/TrEMBL:O86540" FT /protein_id="CAA20494.1" FT /translation="MMFRPALTQVFSTLEPWVAHELRTESGRMTSLSSGESAAHPDRID FT TSRPHPARMYDYFLGGKDNYEVDQRAAEQFMKSAPEVREGVLANRHFMHRAVRHVVAEG FT GVRQILDVGTGLPTEPNVHQIARSVAPGTRVAYVDNDPIVATHSRALADDPDTAVVLAD FT LRDPRSILEHPEVRAVIDFDRPVALLLVAVVHFVADAQDPAGIVATLRDALPAGSYLVL FT SHATGDVHEDRREDAAAVYNKATASLNLRSHAAVLDLFGDFSLVEPGLVRVTDWRPEEA FT RRPDAPPIGIYGGVARKDA" FT RBS 157532..157537 FT /note="possible RBS upsteream of SC1F3.04" FT CDS 157541..158326 FT /transl_table=11 FT /gene="SCO6607" FT /gene_synonym="SC1F3.04" FT /product="conserved hypothetical protein SC1F3.04" FT /note="SC1F3.04, unknown, len: 261 aa; similar to many FT Streptomyces coelicolor e.g. upstream gene SC1F2.03c,E(): FT 0, 48.8% identity in 260 aa overlap" FT /db_xref="InterPro:IPR006764" FT /db_xref="UniProtKB/TrEMBL:O86541" FT /protein_id="CAA20495.1" FT /translation="MTAGTPRPDIDTSKPHPARVYDWLLGGKDNYPVDQRVGETLPAEA FT RGNAARNRAFMHRAAAWLAKNGVDQFLDIGTGIPTEPNLHQIVQAISPAARIVYADNDP FT IVLRHAEALLTGTPEGVTDFLHADVRQPATILERAREVLDFDRPIALSLIALLHFLPDD FT EDPYRVVSTLVDTLPRGSYLLLSHGTADQHPELKQETESAYKKGAIPLRMRTRSEVEPF FT FCGLELVKPGLVFATEWYQEEPAPVRERSGFYAGVARIP" FT CDS 158456..160114 FT /transl_table=11 FT /gene="SCO6608" FT /gene_synonym="SC1F2.05" FT /product="putative secreted protein" FT /note="SC1F2.05, probable secreted protein, len: 552 aa; FT contains N-terminal signal sequence" FT /db_xref="InterPro:IPR007730" FT /db_xref="UniProtKB/TrEMBL:O86542" FT /protein_id="CAA20496.1" FT /translation="MKLRKRRLCAATGVVLGALTALAALPPAAVASPHPGGHPPTARRA FT LPLGPAGLPERRTTTTLQPGVTLTRIVRGNAEDPALHWTVEVSIPGGDTSPDPDAPPTA FT LKDRASADELAAELRRDGFEARVEEVTTPATADYRGGTLGWRVRIGTFDSQTAATAERT FT RLRAAGYSGSAVYTGWDGAATDRGPWHVDVLTIDPRTFRGTLDASYGPDLENRETTSAL FT AASAAATAAVNAGFFVLDPRAGAPGDPAGVGVYDGRLLSEPVAGRPALVVHDDGRRTEI FT ARLTWQGRIATRAASLPLNGVNRVPGLIRNCGGSAGDTPTSLPLHDVTCTNPDELVAFT FT PDYGGRTPGGEGMEAVLDAHERVVELRSPRGGTIPRGGSSVQATGERVADLTATARVGE FT RLRVSATLLDDRGRRMSTSPGTDIVNAGPELVRDGRVHVTPATDGMVHPGDPSWYYGWV FT HKRNPRTVAGVDAAGRTVLVTADGRSTDSLGLSIGESAEVARSLGLRDAVNLDGGGSTT FT MVAEGAVLNSPSDAAGERPVGDALLILPHRHRTRS" FT repeat_region 160141..160224 FT /note="12 degenerate repeats of ACGCAC(C /A)" FT RBS 160238..160241 FT /note="possible RBS upstream of SC1F2.06" FT CDS 160247..161275 FT /transl_table=11 FT /gene="SCO6609" FT /gene_synonym="SC1F2.06" FT /product="putative secreted protein" FT /note="SC1F2.06, probable secreted protein, len: 342 aa; FT some similatity to secreted antigenic proteins 85A, 85B and FT 85C from Mycobacteria e.g. A85B_MYCLE (327 aa), fasta FT scores; opt: 325 z-score: 247.2 E(): 1.6e-06, 28.5% FT identity in 319 aa overlap and to secreted antigenic FT protein PS1 from Cornebacterium glutamicum CSP1_CORGL (657 FT aa), fasta scores; opt: 479 z-score: 421.7 E(): 3e-16, FT 28.2% identity in 333 aa overlap. Contains possible FT N-terminal signal sequence" FT /db_xref="InterPro:IPR000801" FT /db_xref="UniProtKB/TrEMBL:O86543" FT /protein_id="CAA20497.1" FT /translation="MFANVPTVLTPLRARLLLVLAVLLAVLTPTAPEALAAGKPETGAT FT RHGAEVVAVTRVADRQVDLTVRSTALGGRTVEVRLLTPDGWNPHDRRHRQHWPTLWLLH FT GCCGDYTSWTSMTDVAETESLRDVLVVMPEAGWNGWYSDWWNHGQGGDPAWETFHTKEL FT RHLLERDWGAGSNRVVAGLSMGGQGALLYAARHPGMFRATAAFSGSAHPLLNDESVDRI FT MGFFAGQDNDPLRVWGDPVAQRGIWQAHDPFHLAKRLRSIPVYLSCGDGTTGPLDAPGA FT TSALEADFNRQNHALAAELKRVGARHVTTHFYGPGTHGWAYRERELHASLPMLLGALRV FT GD" FT RBS 161416..161419 FT /note="possible RBS upstream of SC1F2.07" FT CDS 161426..162799 FT /transl_table=11 FT /gene="SCO6610" FT /gene_synonym="SC1F2.07" FT /product="putative secreted protein" FT /note="SC1F2.07, probable secreted protein, len: 457 aa; FT contains N-terminal signal sequence. Also contains PS00142 FT Neutral zinc metallopeptidases, zinc-binding region FT signature and Pfam match to entry PF00099 zn-protease, FT Zinc-binding metalloprotease domain, score 15.20, E-value FT 0.81; but no apparent similarities to proteases. Also FT contains possible helix-turn-helix motif at aa 378-399 FT (Score 1335, +3.73 SD)" FT /db_xref="InterPro:IPR019026" FT /db_xref="UniProtKB/TrEMBL:O86544" FT /protein_id="CAA20498.1" FT /translation="MHTGLRRSAAATVLALSVSLTAVDGARAADAPTAAGAPSAGAGPY FT VDVEYFPEPTGGGARTSVPADSPHTQPDGPTATDPQKRTAAASEDGEVVPLAETGPTAD FT RLDVTIVGDGYTAAEQDDFLEDARAKWDEVTDIDPYKSYEGLFNVWAVKAVSEDSGVTG FT DPTRDVVRNTALGSYFWCGDTERLICVDLDRTKAYADRAPATDLVIVVSNSAKYGGAGY FT SGLAADYGYDGVSTLSSDNDRSTLIAAHEMAHSIGLLADEYQYEGYGDYPYPEPAHPNA FT STLTADEMARQRTKWASWLGETDPSGGVVGTFEGADYYEYGVYRPTENSIMRSLNTDRF FT NLPGREAMIAGFYRSANALTPLRNTATRATRFTRLSVELADLGAAKGLSRPQLRWYVDG FT REARHARGRTSVLPAALGVPADRRTHKVTATVVDTTTAVRSHAVRNLTSNSATWTIGR" FT misc_feature 162161..162205 FT /note="Pfam match to entry PF00099 zn-protease, FT Zinc-binding metalloprotease domain, score 15.20, E-value FT 0.81" FT misc_feature 162164..162193 FT /note="PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature" FT CDS complement(162818..163378) FT /transl_table=11 FT /gene="SCO6611" FT /gene_synonym="SC1F2.08c" FT /product="hypothetical protein SC1F2.08c" FT /note="SC1F2.08c, unknown, len: 186 aa" FT /db_xref="GOA:O86545" FT /db_xref="InterPro:IPR011576" FT /db_xref="UniProtKB/TrEMBL:O86545" FT /protein_id="CAA20499.1" FT /translation="MSVQRPAAEQPTTELDARYSSALHPRPGAADVTATEWAEARRRLE FT AAEIFWVTTVRPGGGPHVTPVIAAWHDGVLYFSTGPGEQKARNLAHDAHCALITGGNSL FT TEGFDLVVEGEAEPVGDRAVLEEVIAAYEAKYGAHITSADGTFHGIGDAMRRGDAVLFA FT VAPVTAYGFGRDDGVYSHTRWAF" FT RBS complement(163385..163390) FT /note="possible RBS upstream of SC1F2.08c" FT CDS complement(163403..164332) FT /transl_table=11 FT /gene="SCO6612" FT /gene_synonym="SC1F2.09c" FT /product="putative hydrolase" FT /note="SC1F2.09c, probable hydrolase, len: 309 aa; similar FT to many e.g. XYLF_PSEPU 2-hydroxymuconic semialdehyde FT hydrolase (281 aa), fasta scores; opt: 236 z-score: 348.2 FT E(): 3.8e-12, 29.0% identity in 283 aa overlap. Contains FT Pfam match to entry PF00561 abhydrolase, alpha /beta FT hydrolase fold, score 52.80, E-value 7.5e-12" FT /db_xref="GOA:O86546" FT /db_xref="HSSP:1EHY" FT /db_xref="InterPro:IPR000073" FT /db_xref="UniProtKB/TrEMBL:O86546" FT /protein_id="CAA20500.1" FT /translation="MLTPVASSHSSDPRPPGVELRRVAVNGVELDVALQGEGPAVLLLH FT GFPHTWQLWTRVMGPLAEHHRVVAPDMRGAGASTRAADGYDAGTLACDAEALLEALGVR FT SADVVGIDAGTPPAFLLAMCRPDLVRRLVVMESLLGGLPGAEEFLARGAPWWFGFHAVP FT GLAETVLTGHEARYVDWFLDAGSLGEGVDPAVRDAFVRAYTGTEALRCAFSYYRALPTS FT GEQIAQAAAGGRLTVPTMAVGARPVGRALERQLRPVADHLVGHVIEDCGHIIPLHRPEG FT LLRLLEPFLAAGGTPSGAPMISGPAGSR" FT misc_feature complement(163463..164140) FT /note="Pfam match to entry PF00561 abhydrolase, alpha /beta FT hydrolase fold, score 52.80, E-value 7.5e-12" FT RBS 164440..164446 FT /note="possible RBS upstream of SC1F2.10" FT CDS 164456..164863 FT /transl_table=11 FT /gene="SCO6613" FT /gene_synonym="SC1F2.10" FT /product="conserved hypothetical protein SC1F2.10" FT /note="SC1F2.10, unknown, len: 135 aa; similar to FT hypothetical proteins from several organisms e.g. FT YTFH_ECOLI (156 aa), fasta scores; opt: 315 z-score: 460.2 FT E(): 2.2e-18, 40.5% identity in 116 aa overlap" FT /db_xref="InterPro:IPR002577" FT /db_xref="UniProtKB/TrEMBL:O86547" FT /protein_id="CAA20501.1" FT /translation="MTSSTPRPAHLPRGDLFDPQCPTRRLLDRIGTKWTSMAVKVLAEA FT SPEEVRFAELQRRMTGISQKMLSVTLQGLTRDGLVGRRVEPTVPPRVYYRLTPLGLTLE FT EPLAALREWAEAHMTEVDRARRRSEEEGAAD" FT CDS 165116..166225 FT /transl_table=11 FT /gene="SCO6614" FT /gene_synonym="SC1F2.11" FT /product="putative membrane protein" FT /note="SC1F2.11, probable membrane protein, len: 369 aa; FT contains a possible transmembrane domain around aa 100" FT /db_xref="UniProtKB/TrEMBL:O86548" FT /protein_id="CAA20502.1" FT /translation="MTTTASPDGTPEPRSDDEGAPAEPTGQHPDADGDTPPPPADPAPS FT APQPSANGGGRPDESFEALVSDVLGVDPEASRRKKLRWLFVKAAVGLLGVLGAVLVAYL FT MIKPSTIRENDTNTGIDAAKTPFTVSVRPEEGEPPTWAMVLDRELTADETRKLTTGDPG FT SAFSYLRELGGRPLVYASVMEHAPERYERNTRDGGLELTDAFKMTVLSTRSSAVVIDGW FT KTTGITCHKSTTQTVVAMPPQGGATYQGIRLHLPPRAEEPVLTDDAEGQGESYFGTHYI FT EVGGGQPSGGLRVEAIAPRGQACEWGIKVHYNDSYQKGEWLQLKDAKGKPLRIRTESVP FT ADLRQKWVFASVAWTPCHKNPEGSLCDLV" FT CDS 166237..167439 FT /transl_table=11 FT /gene="SCO6615" FT /gene_synonym="SC1F2.12" FT /product="hypothetical protein SC1F2.12" FT /note="SC1F2.12. unknown, len: 400 aa" FT /db_xref="UniProtKB/TrEMBL:O86549" FT /protein_id="CAA20503.1" FT /translation="MTSLALAALCVQGCSAQPAEEKPAPTSSASAAPFLGNRDYVLPDS FT PFTRDDTVVTATCGMGARYAAVTVRAWDPETWQPRAERTFPIPGDAAFTNYAGAKTVNS FT PLVDLCGMNPDNPSPYEVATLDYMAPRVRALFDLAFTRMAVVLRDPDNKADSHVGYVVS FT GAGLDDVVRLDGAAGADEQNAVMSPDGSSVWFTYTAEGGGKRIGSRPAEGSHHLSDEGP FT AAGHGLPLTVLGKPPRAVQADTVHLAPGGRRLTAKAPKVFGNVFDTWTSSGPLTSRSAH FT RATLLSGCVGVVGWTGDDRVLCRTSTGTFRIMDARTGRASGAPVSVVGPQDGTVAEGML FT VSPDGERFLVAVHEPNARRSDDDYSYRRPDFRVVPTTGSGATTSVVNDLLDTYTMFLSW FT S" FT CDS complement(167453..168883) FT /transl_table=11 FT /gene="SCO6616" FT /gene_synonym="SC1F2.13c" FT /product="putative secreted protein" FT /note="SC1F2.13c, putative secreted protein, len: 476 aa; FT similar to several proteins from M. tuberculosis e.g. FT TR:O05897 (EMBL:Z95121) hypothetical protein MTCY20B11.29 FT (462 aa), fasta scores; opt: 573 z-score: 448.5 E(): FT 9.7e-18, 32.3% identity in 400 aa overlap. Contains FT possible N-terminal signal sequence" FT /db_xref="GOA:O86550" FT /db_xref="InterPro:IPR002938" FT /db_xref="UniProtKB/TrEMBL:O86550" FT /protein_id="CAA20504.1" FT /translation="MAEGIVPRRPTAVVIGASATGLLAAAALADFADVTVVERDRLPDG FT PEPRRGVPQARHAHLVWSGGVKALDDLLPGLTGEVVAHGGRLAHIMGDMVSRAPNEVWF FT RRFTSTHHRNLVCSRDLLDSVLRGRVLADERITLRQETTALRLEGDATAVTGVRIRAGA FT ATDADAGDDAGERTLRADLVVDASGRGSRAPRWLTELGGPSITEREVNAGVAYATRLYR FT APEAARNIDFPLVNVQANPAKAPGRGGIVLPIEGNRWIVTLAGTRGGEPSDDPGAFVDF FT ALNLDDPVIGELVKGLEPLGEIVTTRATANRRRYYERVKHWPDGFLVLGDAVAGYNPVY FT GHGLTVAAQCALAVRDTLGATGLGQPGLARRLQRAAARPVAAAWDLAVGQDALYPGATD FT TRPNGVERLLARFVDKAVETGARNPRALAALLDVMSLERPATRLFSPDMLIPMLIGPRR FT PHLQGSPLTDAERKTAVP" FT CDS complement(168876..169205) FT /transl_table=11 FT /gene="SCO6617" FT /gene_synonym="SC1F2.14c" FT /product="hypothetical protein SC1F2.14c" FT /note="SC1F2.14c, unknown, len: 109 aa" FT /db_xref="UniProtKB/TrEMBL:O86551" FT /protein_id="CAA20505.1" FT /translation="MQRRQRIHDALRTLGPYVDPVLYQRAREAARAGYVQEDDADGVAG FT AVAISAALSTYWQGGPSVAHVPGPRGGAVVGGHIEGIAFALHRPRILQDVRRRMTSTES FT AHHHG" FT CDS complement(169269..169949) FT /transl_table=11 FT /gene="SCO6618" FT /gene_synonym="SC1F2.15c" FT /product="hypothetical protein SC1F2.15c" FT /note="SC1F2.15c, unknown, len: 226 aa" FT /db_xref="UniProtKB/TrEMBL:O86552" FT /protein_id="CAA20506.1" FT /translation="MNGGRAMKWFQRDREERPAGVVPLSGVVKSESAPGQAPPPLGAGG FT PVLQRIGGHSDQVARMTTPAEPVILDITHQGRGHFVVDALDAGLHSQSQLVYTDGPFAC FT RALVNADDRTVRALRVQADGPWAIEATAVSSAAALDGAARCPASNVLRYEGGPGIASLC FT HEGDPRAEDGGYFLVDTYAPDGNGFLDELANHVGPWRGEAPLTGPCLIYARSDGPWSIS FT VQSL" FT RBS complement(169957..169960) FT /note="possible RBS upstream of SC1F2.15c" FT CDS complement(169983..170813) FT /transl_table=11 FT /gene="SCO6619" FT /gene_synonym="SC1F2.16c" FT /product="putative dehydrogenase" FT /note="SC1F2.16c, probable dehydrogenase, len: 276 aa; FT similar to many e.g. TR:O24479 (EMBL:U89510) B-keto acyl FT reductase from Hordeum vulgare (barley) (325 aa), fasta FT scores; opt: 316 z-score: 468.7 E(): 7.2e-19, 36.4% FT identity in 214 aa overlap and HETN_ANASP ketoacyl FT reductase hetN (287 aa), fasta scores; opt: 343 z-score: FT 416.6 E(): 5.8e-16, 36.8% identity in 220 aa overlap. FT Contains PS00061 Short-chain dehydrogenases reductases to FT entry PF00106 adh_short, Alcohol /other dehydrogenases, FT short chain type, score 166.30, E-value 5.1e-46" FT /db_xref="GOA:O86553" FT /db_xref="HSSP:1CYD" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:O86553" FT /protein_id="CAA20507.1" FT /translation="MHEYTNTTALVTGASKGLGEAYARELASRGAHLVLVARSADALHA FT LADEIRATHSVRVDVIAADLSDRRSPQRVLDAVDGLGLDVDLLVNNAGMGAVGPFLVRP FT LAPNLQSVDVNVTALVGLVHLLGARMVERGRGGIVNIASTAAFQPMPYQASYAATKAFV FT LSFTEAVAEEVRGTGVRVMAAHPGATATGFFDRTTASMNPKFTDAPADVAARTLDDFAR FT GRAVSFPGRASQRVGVWASRVLPRTAVTRVTGALNRRLGFRDVSDRDPAATPGQ" FT misc_feature complement(170238..170795) FT /note="Pfam match to entry PF00106 adh_short, Alcohol FT /other dehydrogenases, short chain type, score 166.30, FT E-value 5.1e-46" FT misc_feature complement(170301..170387) FT /note="PS00061 Short-chain dehydrogenases reductases" FT RBS complement(170823..170826) FT /note="possible RBS upstream of SC1F2.16c" FT CDS 170945..171376 FT /transl_table=11 FT /gene="SCO6620" FT /gene_synonym="SC1F2.17" FT /product="conserved hypothetical protein SC1F2.17" FT /note="SC1F2.17, hypothetical protei, len: 143 aa; similar FT to hypothetical proteins e.g. M. tuberculosis TR:P71885 FT (EMBL:Z79702) MTCY3G12.07C (163 aa), fasta scores; opt: 171 FT z-score: 244.4 E(): 2.3e-06, 36.0% identity in 114 aa FT overlap" FT /db_xref="GOA:O86554" FT /db_xref="InterPro:IPR000835" FT /db_xref="UniProtKB/TrEMBL:O86554" FT /protein_id="CAA20508.1" FT /translation="MTRSTLEAAVAANHELFMQTGDRIEAVLTEHGLTPATAQALWAID FT PDQAPPSMKTLAGRLYCNAPNLSFVMNQLTDRGLVERSADPADRRSRVVALTDDGRRVR FT AAVIEATLALTPFARLGDEELRQLVDLLGKALEPAAEGA" FT repeat_region 171409..171453 FT /note="5 x 9bp degenerate repeats" FT RBS 171620..171625 FT /note="possible RBS upstream of SC1F2.18" FT CDS 171633..172907 FT /transl_table=11 FT /gene="SCO6621" FT /gene_synonym="SC1F2.18" FT /product="hypothetical protein SC1F2.18" FT /note="SC1F2.18, unknown, len: 424 aa; some similarity to FT C-terminus of TR:O54229 (EMBL:AJ223176) Streptomyces FT granaticolor Ser/Thr protein kinase (780 aa), fasta scores; FT opt: 260 z-score: 221.0 E(): 4.5e-05, 27.8% identity in 439 FT aa overlap" FT /db_xref="InterPro:IPR011047" FT /db_xref="UniProtKB/TrEMBL:O86555" FT /protein_id="CAA20509.1" FT /translation="MVRRDSGSDDRTPGAFGAPSRRRVLRLAGGGLALAALTAGTVGCD FT EDSVDVEDPGSTGGDEPKGGGNGSGDGGDVGEKGQAPKPLWTKPTSAETYGDNDELVAA FT GGVVIASGSPLAALDAATGGQKWSLPGGAVPGAPLLLSEDTLYLASSEYDGSVIGYAPA FT SGKETWRSRLGKEYRQPRPIAVDEEQVYVLAEILEEDGSSKTNVIAALDSTTGRIAWKE FT QRDVGTEQNGIHAAVRGRHLVYTDFKKNLTVRDTASGGQVWTHKTTRTNYGFFTVHQDL FT VIVPQGNVLQAFNLADGKEKWSLKASDGALFREPAVLEDVLYVADSARTMWAVDPRTGR FT QLWKSEALADAELQVPRQYVKAGDTLYGATDLDKQGGIIAIDARTGEVRWTFNDKTGDY FT HAWLVATDGKRVFALHGKKLHALAV" FT CDS 173142..175028 FT /transl_table=11 FT /gene="SCO6622" FT /gene_synonym="SC1F2.19" FT /product="putative ATP/GTP binding protein" FT /note="SC1F2.19, probable ATP/GTP binding protein, len: 628 FT aa; very weak similarity in C-terminus to a yeast ATP /GTP FT binding protein TR:Q12179 (EMBL:Z73601) Saccharomyces FT cerevisiae chromosome XVI ORF YPL245W (454 aa), fasta FT scores; opt: 201 z-score: 198.6 E(): 0.00081, 25.2% FT identity in 469 aa overlap. Contains PS00017 ATP FT /GTP-binding site motif A (P-loop) and PS00152 ATP synthase FT alpha and beta subunits signature. Also similar to FT downstream gene SC1F2.20, E(): 0, 37.1% identity in 657 aa FT overlap" FT /db_xref="GOA:O86556" FT /db_xref="InterPro:IPR020003" FT /db_xref="UniProtKB/TrEMBL:O86556" FT /protein_id="CAA20510.1" FT /translation="MLFRESAASIAARALDSSLYLHLTEQFVHMHGYRPGAAELRSWER FT SIPALMAALNDAGLGDVEVMLEYALPLNSKRADAILAGVHPTTGEPSYVVVELKQWSQA FT LPNEDDPTLCHVDAYAHPVLNPIEQVRRYCEYLINFNGAVAEHGHRVGGVAFLHNATEF FT GVTGLREIERDGHGLLFTGERRGAFLDHLRTKLSDKHPGARAADELCEGVKVPSKQLMT FT VAAEEVRERTQFVLLDEQQVAYRMVLNAVQKAKNADRKEVVVVTGGPGTGKSVIALQLL FT GELYRRGVPALHATGSQSFTKTMRKIAGARKREVQDLFKYFNSFMTAEKNSLGALICDE FT AHRIRETSANRYTRAAQRTGRAQIDELIDVAYVPVFFLDEHQVVRPGEMGTVADIKEAA FT ARRNIPCHVVPLDSQFRCGGSDAYLRWVVRLLGLEPGGPVVWEPDDRMQLLVADSPQEM FT EAFLEARRAQGYGARMSAGYCWRWSPEPKPGNPLPPDVVIGDWARPWNLRGDRSVSGAP FT PAALWATDPAGFGQVGCVYTAQGFEYDWSGVIIGPDLLWRGDRWVTDRTASKDPVFKKS FT TSDDDVDRLIRNTYKVLLTRGMVGTVVFSTDSETREKLRQLAGGLTREPASV" FT misc_feature 173940..173963 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT misc_feature 174009..174038 FT /note="PS00152 ATP synthase alpha and beta subunits FT signature" FT CDS 175061..177256 FT /transl_table=11 FT /gene="SCO6623" FT /gene_synonym="SC1F2.20" FT /product="putative ATP/GTP binding protein" FT /note="SC1F2.20, probable ATP/GTP binding protein, len: 731 FT aa; very weak similarity in C-terminus to a yeast ATP /GTP FT binding protein TR:Q12179 (EMBL:Z73601) Saccharomyces FT cerevisiae chromosome XVI ORF YPL245W (454 aa), FT Smith-Waterman scores;E: 3.1e-05, 20.4% identity in 499 aa FT overlap. Contains two TTA Leu codons: possible targets for FT action of bldA, PS00017 ATP /GTP-binding site motif A FT (P-loop) and a possible N-terminal signal sequence. Also FT similar to upstream gene SC1F2.19, E(): 0, 37.1% identity FT in 657 aa overlap" FT /db_xref="InterPro:IPR018647" FT /db_xref="UniProtKB/TrEMBL:O86557" FT /protein_id="CAA20511.1" FT /translation="MRPDGLPAWTRPHPHESLVLWGILLVSMLLLRLAARDLLALNARH FT RLVPHLAARWVHFERGDASDGERSAWARSLVSLAEDLVAADRGNVEMIVECSPTVDASE FT DAARTHGQIDVVLVGRHPAEGTLSVQLVELKQWSSVTRVEAATADLVYVEGIEDPVAHP FT ALQLGAYHALFTGPTGPLNGLPFECGGFAYLHNATDESVRALLGVHAPTGPYAHTYTSD FT TRGTLLKDLRRHFTDEDDYSAAEYILHRMNLRNTPLLDAMVRSNGEDTVFTLRGRQKEV FT AEAVLKASELILDPPDREALVPRPQRAVFLVTGGAGTGKSAIGLQLRADLEAAGRTVKY FT ASGSRAFNAAIKENVGYTETEFKERFAYFSSFVTPPDPPLDVLICDEAHRLRDMSKNWR FT LPAEKQGTKPQVDELLDASRLTVFFLDGAQTVRPYEVGTPELIEDAARRHDAVFRHYCL FT EEQYRCGGSDAYIRWARALLGVSPQKAYEWVPDGLMHIEVVDKPDEMEHIVRTEFDAGA FT TARMVAGYCWPWSKPDKDKNLENDVRIGDWHRPWNASSESFCANGEPPSRIWPVHDAGI FT GQIGCVYTAQGLEWDWCGVIMGDDMVWRTDRWVFQRGKQRKDADAGVNRVAKAGSLDPK FT VRTSTLDDEDFARCVRHAYHVLLTRASRATVLYSTDAETRRHLRKLVGETDVHGLRPTQ FT ESIPPELRITRHGGGARSRRARRAWNKAKRKSEMMLF" FT misc_feature 175157..175159 FT /note="TTA Leu codon: possible target for action of bldA" FT misc_feature 175610..175612 FT /note="TTA Leu codon: possible target for action of bldA" FT misc_feature 176000..176023 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT CDS complement(177312..177440) FT /transl_table=11 FT /gene="SCO6624" FT /gene_synonym="SC1F2.21c" FT /product="putative membrane protein" FT /note="SC1F2.21c, putative membrane protein, len: 42 aa; FT hydrophobic in C-terminus. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:O86558" FT /protein_id="CAA20512.1" FT /translation="MDPVEYQPARYARLRKILANVAVNVVANLLVAAMMSAAHLLF" FT RBS complement(177450..177455) FT /note="possible RBS upstream of SC1F2.21c" FT RBS 177647..177650 FT /note="possible RBS upstream of SC1F2.22" FT CDS 177655..178320 FT /transl_table=11 FT /gene="SCO6625" FT /gene_synonym="SC1F2.22" FT /product="hypothetical protein SC1F2.22" FT /note="SC1F2.22, unknown, len: 221 aa" FT /db_xref="UniProtKB/TrEMBL:O86559" FT /protein_id="CAA20513.1" FT /translation="MLGPPSSRRMAGYGGGREAPSADGGPVKLTYVCFEGTPQELDESE FT AVRELVRQWSGTVDTVRRTPRAVVDPESDDEVDFGWLVEGDVPGVVEEGQSTVKAQLAF FT NPAAQQFLDFMMEATSWEGVVVHGIKRKTWQEGDPLDYTGYLRLRRKGSQYGGFVYVFA FT STGVINFRLQYSDEIAELAPDAYPLTKGNYQYRVNIQIHDESTLKQALALAELAYDAT" FT RBS 178520..178524 FT /note="possible RBS upstream of SC1F2.23" FT CDS 178537..183210 FT /transl_table=11 FT /gene="SCO6626" FT /gene_synonym="SC1F2.23" FT /product="putative protein kinase" FT /note="SC1F2.23, unknown, len: 1557 aa; some simlarity to FT several protein kinases e.g. ABL_MLVAB tyrosine-protein FT kinase transforming protein from Abelson murine leukemia FT virus (746 aa), fasta scores; opt: 84 z-score: 234.0 E(): FT 8.6e-06, 24.7% identity in 364 aa overlap. Contains PS00107 FT Protein kinases ATP-binding region signature, Pfam match to FT entry PF00069 pkinase, Eukaryotic protein kinase domain, FT score 18.10, E-value 0.00062 and possible helix-turn-helix FT motif at aa 1027-1048 (Score 1753, +5.16 SD)" FT /db_xref="GOA:O86560" FT /db_xref="InterPro:IPR017441" FT /db_xref="UniProtKB/TrEMBL:O86560" FT /protein_id="CAA20514.1" FT /translation="MREGRWVTVTESEFEHERRGLEAIRQKLPDGDPWRAWSNFTFTAN FT TGHVREVDLLVVAPGGLCMVELKDWHGSVTSENGTWVQTTPGGRRRTHGNPLHLVNRKA FT KELAGLLAQPGAKRVWVAEAVCFTDNGLRVRLPAHDQNGVYTVDELVDMLKQAPSDERR FT RVTAIGSREVAAALKNIGIRKSDAQYKVGPYELERKSFDSGPTWADYLARHSDLPEAAR FT VRIYLSERGSDASLRQSVENAARREAAVLGRFKHPGAVQLKQYFPSGHAAGPALIFDYH FT PHTQKLDEYLVQYGEKLDILGRMALVRQLAETVRSAHASRIHHRALAARSVLVVPRSRG FT GKGRAVGEEAAWLTPQLQISDWQIATQRSGDSSQGQGMTRFAPTALSAMHLADDADAYL FT APELTALNPDPVYLDVYGLGVLTYLLVTGKAPAASQAELLARLEAGEGLRPSSLVDGLS FT EDVDELVQAATAYRPGQRLSSVDEFLELLEVVEDSLTAPAAALDGPAEDETGASADKDP FT LEVVAGDLLAGRWEVRRRLGTGSTSRAFLVRDLEAETRRTRPLAVLKVALSDSRGEILV FT REAEAMRRLRPHSGIIRLAEPEPLHIGGRTVLALEYVGDERDDDGPGAEGATRPRRREE FT TVARQLREHGRLPVDQLEAYGDYLFGAVDFLEGEGIWHRDIKPDNIAVRIRPNRTRELV FT LIDFSLAGYPAKNTDAGTDGYLDPFVDVITRGSYDSHAERYAVAVTLHQMASGELPKWG FT DGSVLPRMTDPKEWPYPTIAAEAFDPAVRDGLVAFFQKALHRDAGKRFPELKPMRDAWR FT KVFLDASQTVPSSHRTRPAAPADGAAPAEGAAAGIADAEPETAEQQRDRLAAEVTRDTP FT LTVSGLTPAAQSFLYGLGITTVGELLDYSRRKLVNAPGLGAKTRNEVQQRQREWGERLR FT EAPVSPLTPKGRAEAKEELEQLTAAESALVGQLATGESAGALSARTLRSVSLDTLATVL FT VPAVNNNGSNRNKAEMVRLLLRLPDEHGVLPGIGVWPKQKDVADALGLSHGRIPQMLKD FT ERKRWKAEPAVQALRDEIIELLASMGRVASAVEIADALAVRRGTHLAGREQRRAMALAA FT VRAVVEVEQLVPQEVEFQHQPNRKATDESLGAGLLALDVREDDAPDTPTAPGLLDYATR FT LGKTADRLARLDTLPTAATVLAELGALTVPPGAVDWDERRMVELAAAASVNAAATPRLE FT IYPRDLSLVRALRLTQAGLVRWIPGVPEGRQPGLTGEDVHERVRARFPELVVPDGRGGT FT AHELPTAGPLTKALRDAGFELSLSMREDTGTLRYLPTRVDEASSYLTTGAWRQSTRTGT FT VTRYADDPQLAGAVRAEERLLASAHRDGYRVLTVRQQLVRDAVRELGAERLGGQAVSVT FT ELFLEALHGQVTPGTKPTWETLLKADAAEPGSKGAVRFAEYARTAWGSVEPRIAELLGD FT GGGGAGPVLLTEAGVFARYDAMGVLDRLASAARRGGRGLWLLVPQSDPSREPRLGQVAV FT PYQAGLGEWIQLPDTWVGNRHRGSGEVVASGVEGDAK" FT misc_feature 180124..180318 FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 18.10, E-value 0.00062" FT misc_feature 180142..180228 FT /note="PS00107 Protein kinases ATP-binding region FT signature" FT RBS 183196..183199 FT /note="possible RBS upstream of SC1F2.24" FT CDS 183207..186839 FT /transl_table=11 FT /gene="SCO6627" FT /gene_synonym="SC4G2.01" FT /gene_synonym="SC1F2.24" FT /product="hypothetical protein" FT /note="SC4G2.01, unknown, partial CDS, len: >378 aa; FT continuation of SC1F2.24" FT /note="SC1F2.24, unknown, partial CDS, len: >862 aa; FT contains short segment of similarity to a Helicobacter FT pylori gene described as TR:O26046 (EMBL:AE000649) type IIS FT restriction enzyme R and M protein (1279 aa), fasta scores; FT opt: 92 z-score: 267.0 E(): 1.3e-07, 30.5% identity in 118 FT aa overlap. Also contains PS00092 N-6 Adenine-specific DNA FT methylases signature and probable coiled-coil from a 5-39. FT Note that this CDS is relatively more AT rich (approx 60% FT GC) than the genomic average (72%)" FT /db_xref="GOA:Q8CJM2" FT /db_xref="InterPro:IPR002052" FT /db_xref="UniProtKB/TrEMBL:Q8CJM2" FT /protein_id="CAD55384.1" FT /translation="MIDRKALLNDLKQQVKAVEADLGKQVKALDEVGARLRAEYDQARK FT LGRTAATWNSWLDERVTQVAVAWVLGTVFVRFCEDNRLIPEPYVTGPDNYRRDLAETRY FT DVYVEADDDPTYRGWLRRAFAELGDGQAGRLLFDSDHNPLYQIPLSHDGARELVEFWRQ FT RDEEGALVHDFTDPLSADGTEGWGTRFLGDLYQDLSEAARKTYALLQTPEFVEEFILDR FT TMNPAVREFGYEELKMIDPTCGSGHFVLGAFRRLVRLGGENQPGKDVHQRVRAALDSVH FT GVDINPFAVAIARFRLLVAAMAASGVRTLDEASKYEWPVHLAVGDSLIKSGSQQGSLFG FT ESDDDLTDELAEFKYATEDVGEHPEMLRPGRYHVVVGNPPYITVKDKSLNALYRELYPA FT CAGKYALSVPFAQRFFELAKREDAEGSGYGMVGQITANSFMKREFGTKLIEGYFGHAVE FT LTEVIDTSGAYIPGHGTPTVILVGTRRGGDGRSPVIRTVRSVQGEPVAPENAEEGLVWR FT AIVEQIDKPGSVSQWVSVDDLDREKYFSKQPWVLADGGQEMLEQINAASHAILKRDLHR FT IGFYGIMGADDAMSAVPRTFRRNNAESEYVRRLVVGDEVRDFRIADGDDAFHPYGSQRD FT LVGPDAFPNLAAWLWPYRTELGGRATFSGGTYFADGRPWWEWHQLPKDVGAHAWSLNFA FT FVATHNHVVLDRSGCAFTRTAPVIKLREGASEEEHLRLLGLLNSSTAGFWLKMVSYPKG FT GDPVGDEGARVSVHPWSDRYEFTGTKLQEFPLPSEYPTGLGTALDALAQRLAAASPAAV FT AAEAVPIAGLLREARTRWEAIRSRMIALQEEMDWQVYSLYKLHSEDLRVSEDPDDTNIP FT ELTLGGRAFEIVLARRVAAGEASDEWFKRHNSTPITEIPAHWPAPYREIVQKRIDAIES FT NRAIGMVERPEYKRRWATEGWDALQEKALRSWLLDRMENRDLWCDENGQPTILTLARLT FT DALSRDEDFASVAKLYAPRKELAKVVAELITDEHVPFLSALRYKPSGLKKRADWEEVWD FT LQRKEDAAPDEPAKRKIRDSIPVPPKYTSADFLRPSYWKARGKLDVPKERFVSYGQTNA FT ATPELYGWAGWDHREQAQALATYFTNTALSTKEITPFLAGLLELQPWLSQWHNEFDMLY FT SGSPADFFAGYRQQKQGEHGLTDDDLRGWRPPAATRRRRAAAKQ" FT misc_feature 184329..184349 FT /note="PS00092 N-6 Adenine-specific DNA methylases FT signature" FT CDS complement(186766..187356) FT /transl_table=11 FT /gene="SCO6628" FT /gene_synonym="SC4G2.02c" FT /product="conserved hypothetical protein" FT /note="SC4G2.02c, unknown, len: 196 aa; similar to S. FT coelicolor TR:Q53897 (EMBL:X60316) abaA gene ORFA (192 aa), FT fasta scores; opt: 245 z-score: 250.4 E(): 1.1e-06, 32.9% FT identity in 164 aa overlap. Also similar to SC10A5.20 FT (32.7% identity in 147 aa overlap) and SC7C7.02c (38.7% FT identity in 150 aa overlap) and to TR:Q9RKV5 FT (EMBL:AL132824) Streptomyces coelicolor putative regulatory FT protein SCAH10.02, 160 aa; fasta scores: opt: 436 Z-score: FT 526.8 E(): 1e-21; 51.449% identity in 138 aa overlap" FT /db_xref="GOA:O86675" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:O86675" FT /protein_id="CAA20539.1" FT /translation="MKSATPSNGHMPQHMALEREFTMRFTSTPRGARLARRLVSHRLND FT WGHPYATSVNETLTLITSELTANAVRHGHIPGRDFHVQLTLTDDIFRIEVTDTCAEKRP FT PASPSAADALSESGRGMLLVAALADDWGVSPRPAAPGKTVWAQLHVRTKGHPLTHRVAP FT EPTDVDLLLTTASLLRDDVGSRPEDASHGGRRQ" FT RBS 187507..187511 FT /note="possible RBS upsteam of SC4G2.03" FT CDS 187519..188352 FT /transl_table=11 FT /gene="SCO6629" FT /gene_synonym="SC4G2.03" FT /product="conserved hypothetical protein SC4G2.03" FT /note="SC4G2.03, hypothetical protein, len: 277 aa; similar FT to TR:Q9F345 (EMBL:AL391751) Streptomyces coelicolor FT hypothetical protein SC9E12.10c, 287 aa; fasta scores: opt: FT 769 Z-score: 890.8 E(): 5.5e-42; 48.736% identity in 277 aa FT overlap" FT /db_xref="GOA:O86676" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:O86676" FT /protein_id="CAA20540.1" FT /translation="MGDEVQQPEEYEVGTGMLCVFGRQLKLFRERAGLDRAGLGSLTGY FT SASTIASFEQARRIPQPKFIDQADEVLGAGGVLSASKEEVARAQYPAFFRDAAKLEAEA FT VELFVYDTHVVNGLLQTEGYMRALLGMRRPLLDEATIEQRVAARLTRQKIFDRWPAPLL FT SFVMEEPVARRPLGGEQVWRGQLEQLLSLGQKRSVELQMMPLDRQDNAGVDGAFTLLTP FT RQGQQVGYMEAQGRSTLATERDVVHALSARYGIIRAQALTPSESLALIEKLLGER" FT RBS 188341..188344 FT /note="possible RBS upstream of SC4G2.04" FT CDS 188349..188552 FT /transl_table=11 FT /gene="SCO6630" FT /gene_synonym="SC4G2.04" FT /product="hypothetical protein SC4G2.04" FT /note="SC4G2.04, unknown, len: 67 aa; similar to S. FT coelicolor TR:Q53896 (EMBL:X60316) AbaA gene ORFD (75 aa), FT fasta scores; opt: 120 z-score: 206.5 E(): 0.00029, 43.8% FT identity in 48 aa overlap" FT /db_xref="InterPro:IPR007278" FT /db_xref="UniProtKB/TrEMBL:O86677" FT /protein_id="CAA20541.1" FT /translation="MNAEAKRGPEPALVWGKSSYSGAEGGQCVEVAAAPARVHVRDSKD FT TTRAALAVEPTAWAAFVEFAAR" FT stem_loop 188569..188612 FT /note="hairpin loop with 19 /20 bp stem" FT CDS 188814..189689 FT /transl_table=11 FT /gene="SCO6631" FT /gene_synonym="SC4G2.05" FT /product="putative membrane protein" FT /note="SC4G2.05, putative membrane protein, len: 291 aa; FT similar to TR:AAK74714 (EMBL:AE007366) Streptococcus FT pneumoniae conserved hypothetical protein SP0558, 271 aa; FT fasta scores: opt: 522 Z-score: 580.2 E(): 1.1e-24; 37.008% FT identity in 254 aa overlap. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:O86678" FT /protein_id="CAA20542.1" FT /translation="MKQGKEVENPESRFFAVLLAAAKLPGVRIHREAYLRSALARHCSE FT DEIRRAVEKTPAAAGITVELLDKVAKDSIRYETAKVSALSAAAGIPGILALPATVPADV FT AQYVGHMLRIAQKLAYLYSWPDLFSDEGDDVDDATMGVLTLFFGVMFGTQSANVAVGKV FT AGMMSKQVAKKLPQKALTKGVIYPLVKKSAAYLGVQMTKQSFAKGVSKAIPVVGAVVSG FT GLTLATYLPMAKRLKKHLAGLPLADPSYEASEGDVVDGEVVEEHETLAPADAEPHDADT FT TTPKLEEPRP" FT RBS 189850..189854 FT /note="possible RBS upstream of SC4G2.06" FT CDS 189865..190494 FT /transl_table=11 FT /gene="SCO6632" FT /gene_synonym="SC4G2.06" FT /product="hypothetical protein SC4G2.06" FT /note="SC4G2.06, possible membrane protein, len: 149 aa; FT start uncertain" FT /db_xref="UniProtKB/TrEMBL:O86679" FT /protein_id="CAA20543.1" FT /translation="MTGQSIAAGSRYCRYISLVGLIHESPSWRAGRPAVPVVCLATVCL FT LSTCLSMVGRQGGGGVDPISVGLLLALSGGAGGEIGRQAWVALSALVRRPFRGGHGTED FT VPDVSMADAELAELERSPADAARAHALSTALAVRAAVDAEFRNGLEEWREQARHVCSGD FT GEVKNSISGGTFHGPTLLGRDFSNTSFAAAPAPPAEPGPETPTVRG" FT RBS 190487..190490 FT /note="possible RBS upstream of SC4G2.07" FT CDS 190499..192409 FT /transl_table=11 FT /gene="SCO6633" FT /gene_synonym="SC4G2.07" FT /product="putative transcriptional regulator" FT /note="SC4G2.07, possible transcriptional regulator, len: FT 636 aa; similar to part of AFSR_STRCO regulatory protein FT AfsR (993 aa), fasta scores; opt: 512 z-score: 733.8 E(): FT 0, 35.5% identity in 521 aa overlap. Contains PS00017 ATP FT /GTP-binding site motif A (P-loop)" FT /db_xref="GOA:O86680" FT /db_xref="InterPro:IPR000767" FT /db_xref="UniProtKB/TrEMBL:O86680" FT /protein_id="CAA20544.1" FT /translation="MAGAVPHGEAEPGRPVANHISGGVFFHAVLQGRDITVQLPPQTAP FT ALSGLPPASSAFAGRDEQVEELLGMLARGRPQQAVVVAAIAGLGGIGKTELVVQTASRA FT LKQPGWFPGGVLFVDMFGYDQERRLTPERALVGLLRALGVDKEQIPSDVQDLSRLYRSA FT LAALAQAGSRVLVVIDNASSTDQVRPLVPADGITAALVTSRDTLDLDGRLYDLGTLSDS FT ASVELLNRVLREARGPGDTRIHDEPEEAVALARLCGGLPLALRIAASLLVDSPTRPLSS FT VTQALSVEQSRLHRLRRKDRTVRAAFDLSYRRLPSAHQRLFRLLSLNQGPDISTEAALH FT LSDLDAYETEELLQDLARCHLIEPGITWGRWRLHDLVRIYAGELGGQEANVDRRDAVRK FT RLHGHYLHTARAARSHLAVTREPLSILREPRSPRFNTTKEAEGWFEQECQNLISLITIA FT PVNARSSTAVWLAVFLTPYLRWEYRFRDMRAVVAAVEDLVCERADCPAGTGGALLLISY FT ELDRVDFTYWAVDLLVDAIEFLCSDGNRRFEVVAMQEIHHHVLKIIRRTGFLPSDIASK FT LDRLTLAHAHLVPSEHVEGKRTCWCRQCWLQRIGTSRTLPTVISRPDAAPFPLRYRRLP FT G" FT misc_feature 190757..190780 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT misc_feature 192314..201774 FT /note="99.8% match to SCPGLYZ L37531 Streptomyces FT coelicolor bacteriophage (phiC31) resistance (pglY and FT pglZ) genes, from 1 to 9461" FT RBS 192446..192450 FT /note="possible RBS upstream of SC4G2.08" FT CDS 192458..192646 FT /transl_table=11 FT /gene="SCO6634" FT /gene_synonym="SC4G2.08" FT /product="hypothetical protein SC4G2.08" FT /note="SC4G2.08, unknown, len: 62 aa" FT /db_xref="UniProtKB/TrEMBL:O86681" FT /protein_id="CAA20545.1" FT /translation="MALYPRFDAIGRGIRRVTETYDLPFAVVTIRTCWTLPIGAMAAVA FT RAVREAYGTGWGERVPM" FT RBS 192926..192929 FT /note="possible RBS upstream of pglY" FT CDS 192943..196827 FT /transl_table=11 FT /gene="SCO6635" FT /gene_synonym="SC4G2.09" FT /gene_synonym="pglY" FT /product="bacteriophage (phiC31) resistance gene pglY" FT /note="SC4G2.09, pglY, len: 1294 aa; 99.8% identical to S. FT coelicolor TR:Q53942 (EMBL:L37531) bacteriophage (phiC31) FT resistance gene pglY (1294 aa). Contains PS00017 ATP FT /GTP-binding site motif A (P-loop)" FT /db_xref="UniProtKB/TrEMBL:O86682" FT /protein_id="CAA20546.1" FT /translation="MAQPPLLRDVIDIKESISTSDFVLSLAEATTPAGAQHALRDYVVT FT ERLLENFDEALALIKSSLDGHRSKAAYLHGSFGSGKSHFMAVLYALLSGDQAARARTEF FT DPVLTKHQWLSTDGKKFLLVPYHMLGAKALEQRVLGGYVTHVKKLCPEAPTPQVYRTDS FT LFADIRAMRANMGDEAVIRALGTSGADDAEEDEWGEGFAWTPQLLDTALAAEESHEAGV FT HLNLTNPSTPAELRAKLVNDAGTNLLPGFTQNAAEDEHGFISLDAGLSVIAEHAKSLGY FT DGLILFMDELILWLATLIHDQKFVAREASKITNFVEGGDARRAIPVMSFIARQRDLREL FT VGEEVSGAAESSIQDTLNLASGRFDKITLEDRKLPQIAHARLLKPKDAEAAQQVDAAFE FT QTKRVGPQVWDTLLGSEKGTTGADAESFRLTYPFSPAFMDTLVHISSALQRSRTGLKLM FT GQLLADHRDELRLGQLVPVGDLYPVIAQGGDKPFTDSLKVVFEAADKLYKTKLRPYLLS FT SYDITEDDVEQYRNRPESLTDPKKLNGCRMFTGDNRLVCTLLLSALAPSVPALSELTIR FT RLGALNHGSVLAPIPGAEVGIIKNKVAEWAARFPEIKETGTDANPGVRLELSGVDVDSV FT IANAQVNDNPGNRVALARRLLSEELGVEHGQLSDQLGFTWRGTARTAEIVFGNVADEDE FT LPDHDLMPQEEGRWRIAIDLPFDEGEWGPVEDVNRVQRLRERQQGERSRTIAWLPAHLS FT ATRFADFRRLVVIDKALADEHRFDTQYAGHLNADNRSRAKGLLETQREALLKQAKGAFK FT QAYGLAQKQAADVVPDFDDHLVALPDVDGLTLSFGQSLHDGIRHVAGKLLTHQYPAHPD FT LDPDATGTAVKPADTKKVFAHVRAAAEARDGRIEVPAADRKLMQRIAGPLRLGQQKEAY FT FELSRYWGDHFRQLARSQGVTGDLSLITLTDWTDRPDPRGLPDFLARLVVAAFAEMDDR FT VWVRGGTVLDPAPELAAIKDHDALRSQPLPAESDWDTARQRFETVFGAKPPALRRGRMV FT NQFARQIIEAARDYRDHAADLVHQLEAHASFLGLDQTADTGRLALARRSLQLLDALTAE FT AGKGAAGAKKTVEALASFDLGETSADRYGTSIKKARAVAEAVASAPWSTLELAAGLGPE FT GEALLDSLRNVARDDQRTADLRDALARTQREVVALIKRTQAAATPPPAPAASQPTAGDL FT SLDTPTSDPRIPYTSQETPTSSGGAGTARTSGGRRTTAARAVTDLQAELSDLAVRHPEA FT TIEITWRVVE" FT misc_feature 193165..193188 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT CDS 196824..199748 FT /transl_table=11 FT /gene="SCO6636" FT /gene_synonym="SC4G2.10" FT /gene_synonym="pglZ" FT /product="bacteriophage (phiC31) resistance gene pglZ" FT /note="SC4G2.10, pglZ, len: 974 aa; 98.9% identical to S. FT coelicolor TR:Q53943 (EMBL:L37531) bacteriophage (phiC31) FT resistance gene pglZ (974 aa)." FT /db_xref="InterPro:IPR013973" FT /db_xref="UniProtKB/TrEMBL:O86683" FT /protein_id="CAA20547.1" FT /translation="MTDTTVAVPGAVRLNTATVTQYLSSQSSLVASLTGDGGGRRRAVL FT LRSAPQWDGPAEPAWGEGRTAGIAVAPSPLAVHELVLDHLAARRPGPPVLVVLTDREQH FT ELDPAILARVHKLRIDTVDGWDVVREAFGARQIDPRLKDVNWAAEALLDATPPGSWPAV FT PGGWLSRQYALTALAQRRLRLGRYDTEGGPRRPGDDRLDAQALLHWSTRPGAPERLLTL FT RGPERAGLTAFLGEEDQAGLAGRTLLALVDAERGEDAAAFGLVCAALWQHAEPAPETYR FT ARGRAERYFGDRPPATGDQLDALVTVFGRATEEHVTTLLAAGHRTAGTDADQAREARRT FT TGTVLDRAAALARQFGAEEAVAASPVLRGGLEARFTAVGRALAAGDTTAVADAVRRLEN FT HRLAAEPEESARIERARMGQRLARWLATDPPTDALTVADALRRHVAETGWADLALEHIE FT AGGDQGPVLKAAYDTLGTRVRDRRRQIDASFARSLAAWTQSGTQPGSMLTVETFLDRVV FT GPLVRRGEERRTLMLVLDGMSAAIANELGEELRRSWAEFDPLPEGDTPYRRAMAAALPT FT VTAVSRTSLFAGTLTKGTQADEKRLFPALKLWGGAPAAVFHKDDLRTETAGETFGPALT FT EALADGRTHVAVVLNAIDDRLAKEQKLGDGAWRIDDVPGLRDLLRVAATQGMAVVLTSD FT HGHVVDRHGTKVDPAAAPESARHRLIGGGPLAEREITLSGPRVIWPEPGASIVALWDAD FT SRYTALKAGYHGGASLAEVTIPALAFLPFGAEPPKGWRELGDQRPVWWAPEETGKAPLP FT DEYTARPVAATASAPKKPTAKAKKDQAEVARMHHGALFDVALTTEGDDALLTPTVVSRT FT ETLVTALLDSETYQAQLGGLARKPQQEQVHKALTTLLDSGGTLPVTALAQRVGMPVTRG FT VGFAAVLGQLLNYDGVQVLETLPDGRTLRLHAALLREQFALGAG" FT CDS complement(199817..200869) FT /transl_table=11 FT /gene="SCO6637" FT /gene_synonym="SC4G2.11c" FT /product="hypothetical protein SC4G2.11c" FT /note="SC4G2.11c, unknown, len: 350 aa; identical to FT TR:Q53944 (EMBL:L37531) ORF3 downstream of PglZ (350 aa)" FT /db_xref="InterPro:IPR000644" FT /db_xref="UniProtKB/TrEMBL:Q53944" FT /protein_id="CAA20548.1" FT /translation="MTTRPHERDVSSLKGRTVSVQEILDLFEVRVRDHRTVHRISQALT FT DAGLTTLPDFAVCGLRSTVDVVPLAAVPAQRTPADTDDESDATEEALPSHALPQRLLLG FT DIPSARRGVVSVGPGTALSQTTFLMRTKGLAQVPVTTGMAQVHGVVTWGSVAKMYEAGK FT AATLDNAMEKDSLPVADARQEFFAALPVIREHGYLLVRGDDGCLSGIVTAADVTDRFEG FT AARPFFIVGEIESLLRRCLGAALDAEAIKAVQTNKKQEHRTGQVSDLMFGDYLRLLDGE FT QTKQSFAERADLNWEALKWPNMPREQFVGLLKRVKDIRNRIAHFDEKPLPPEMIDELTT FT FAKVLRAFAS" FT CDS complement(200866..202683) FT /transl_table=11 FT /gene="SCO6638" FT /gene_synonym="SC4G2.12c" FT /product="hypothetical protein SC4G2.12c" FT /note="SC4G2.12c, unknown, len: 605 aa; identical to FT partial S. coelicolor sequence TR:Q53945 (EMBL:L37531) ORF4 FT downstream of PglZ (>302 aa) and weakly similar to FT Y686_METJA hypothetical protein MJ0686 (Methanococcus FT jannaschii) (580 aa), fasta scores; opt: 260 z-score: 416.1 FT E(): 6.2e-16, 23.3% identity in 601 aa overlap. Contains FT TTA Leu codon; possible target for action of bldA" FT /db_xref="InterPro:IPR018651" FT /db_xref="UniProtKB/TrEMBL:O86684" FT /protein_id="CAA20549.1" FT /translation="MAALDNVKLKDVLADVASGSLQLPDFQRNWKWDDDRIRAIIATVT FT LDYPLGVVMTLQTGGATRFRSRTLTGAQPDGDPAADLLLLDGQQRLTSLFQSLWLDAPV FT ETADSRGKAIQRWYYVDIAKAVGPSADRDEAVVSVPADKVLRTDFNRTVVLDLSTTEAE FT CAAGLFPLHFVFDAQRVNEWKRAYIKADEERNWDRWGQFDEAVLQQVRAFQVPMIRLAA FT STSMDAVCAVFERVNTGGVPLNVFELLTATYAGDGDYVERTGDYYQLPEVWREIKQALA FT SKYPVFGRLDSGLENGLSSIDFLQAIALVRTWERKQSGIGTTVSCKRRDLLDLPLADFV FT RLAPKLADAFAWVGDFLERQSIVRPADLPYKTQLVPLAAVRAILDTGADGLGAEEKTEQ FT WYWCGVLGEMYGGSTETRFTKDVEQLVPWISQGERAPETVTEAFFFAERLDTLTTRNSA FT AYKGIYALLIKQGAVDWHHTDAPLSPGRLDEYGVDVRQIFPKTWFRRGNSEGLPTSSIV FT NKTPLSYRAAMDMTGAPSSYLSTMVAASDMRPEWFDDVLSTHLIDPDALRENDYGRFYR FT DRSKQLQELVHSAMGKRTMLRDLPEGNLR" FT RBS complement(200880..200884) FT /note="possible RBS upstream of SC4G2.11c" FT misc_feature complement(202621..202623) FT /note="TTA Leu codon; possible target for action of bldA" FT RBS complement(202688..202691) FT /note="possible RBS upstream of SC4G2.12c" FT CDS 202859..204208 FT /transl_table=11 FT /gene="SCO6639" FT /gene_synonym="SC4G2.13" FT /product="putative ATP/GTP binding protein" FT /note="SC4G2.13, probable ATP/GTP binding protein, len: 449 FT aa; similar to TR:O26411 (EMBL:AE000816) hypothetical FT protein MTH311 (Methanobacterium thermoautotrophicum) (411 FT aa), fasta scores; opt: 596 z-score: 528.7 E(): 3.3e-22, FT 30.5% identity in 393 aa overlap. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop)" FT /db_xref="UniProtKB/TrEMBL:O86685" FT /protein_id="CAA20550.1" FT /translation="MSTTGSPRPAQVSAARRRTVIDALRRGAVPESGLDLLATGLGRFE FT AALDAELDGVMSGGSVFKAVRGEYGAGKTFFTRWLGERAKRRNFAIAEIQISENETPLH FT KLETVYRRLTERLTTSSFPPSALRPVVDAWFYALEEDALAAGATEEELPAEVEKLLLAR FT LAEVSRHAPSFATALRGYRAALAEGDEATASAVLAWLGGQPHVAAAARRSAGVRGDLDH FT FGALGFLQGLLTVLRDSGHTGLFVVLDEVETLQRVRSDARDKALNALRQLIDEVHSGRF FT PGLYLAITGTPAFYDGQQGVQRLAPLAQRLATDFTTDPRFDNPRAVQIRLPGFSRESLV FT GLGLTIRELYADAAQAPERVRAVVDDVYVADLAQAVGGALGGKVGVAPRLFLKKLVGDV FT LDRVDQFDDFDPRQHYRLTVASSELTDVERNLAATVTGGSVSADDIELEL" FT misc_feature 203057..203080 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT RBS 204199..204202 FT /note="possible RBS upstream of SC4G2.14" FT CDS 204208..206403 FT /transl_table=11 FT /gene="SCO6640" FT /gene_synonym="SC4G2.14" FT /product="putative ATP-dependent helicase" FT /note="SC4G2.14, probable ATP-dependent helicase, len: 731 FT aa; similar to many predicted helicases e.g. C-terminuis of FT LHR_ECOLI probable ATP-dependent helicase LHR (1538 aa), FT fasta scores; opt: 332 z-score: 570.0 E(): 1.7e-24, 29.3% FT identity in 638 aa overlap. Contains PS00017 ATP FT /GTP-binding site motif A (P-loop). Contains Pfam match to FT entry PF00271 helicase_C, Helicases conserved C-terminal FT domain" FT /db_xref="GOA:O86686" FT /db_xref="HSSP:1JR6" FT /db_xref="InterPro:IPR014001" FT /db_xref="UniProtKB/TrEMBL:O86686" FT /protein_id="CAA20551.1" FT /translation="MADADSSPETEGADVLDRLDPVVLHHIVNTLGWSDLRPLQRAAIT FT PLMEGEDAVLLAPTAGGKTEAACFPLLSAMAEQKWTGTSVLYLCPLKALLNNLVSRVDT FT YTQWLGRRAALWHGDTKESQRQRIRTEAPDVLLTTPESLEAMLIGVKTDHARLLGSVRA FT VVVDEVHAFAGDDRGWHLLAVLERLEQVTGRPIQRIGLSATVGNPDQLLDWLQGAGVET FT RAGRVVAPGVTLPAFEAVGSDRKPTAEEVPRPAGEVELDYVGSLDNAAKLIATLHRGEK FT RLVFCDSRAQVEQLGAALRAREVTVFLSHASLSVDERTRSEQAFAEARDCVIVSTSTLE FT LGIDVGDLDRVIQIDSPATVASFLQRIGRTGRRAGTVRNCLFLTTRKDTLLQAAGLLLL FT WSRGWVEPVKPPPEPRHLVAQQLLAVTLQQHKLGDQLWDRQWNGLAPFDQSAAPILRHL FT TEEGFLDSDGGLLFVGPEAERRFGKRHFIELTASFTAPPQFTVLSGRTEIGRTDPSVLT FT EERPGPRRLLLGGRSWQVTYIDWLRKRVFVEPADSGGIAKWMNGGIAGLTYALTRAMRE FT VMLGEDPPVVLTRRAQARLAEQRESDAPDTVHPDGTLVTRAGNDVRWWTWAGYRANATL FT AATLQSVTDPLQRPTDCWLRLREDLDPADWHAARKSVGESLVLPDVDPRAVRGLKFSAA FT LPERLAIATVAARLADFDSAWFVLSEAVRFVVSSDRA" FT misc_feature 204376..204399 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT misc_feature 205084..205329 FT /note="Pfam match to entry PF00271 helicase_C, Helicases FT conserved C-terminal domain" FT CDS complement(206413..207627) FT /transl_table=11 FT /gene="SCO6641" FT /gene_synonym="SC4G2.15c" FT /product="conserved hypothetical protein" FT /note="SC4G2.15c, unknown, len: 404 aa; N-terminus is FT similar to extreme C-terminus of TR:O26587 (EMBL:AE000832) FT DNA helicase related protein MTH487 (Methanobacterium FT thermoautotrophicum) (1157 aa), fasta scores; opt: 467 FT z-score: 553.7 E(): 1.3e-23, 43.7% identity in 174 aa FT overlap" FT /db_xref="GOA:O86687" FT /db_xref="UniProtKB/TrEMBL:O86687" FT /protein_id="CAA20552.1" FT /translation="MVTVARLNVAVTRARHRVEVVASFHGADLPDNANKSVQHLKRYLQ FT YAEQGPTVLAPAAPDAEAAPESPFEEDVLAVLRDWGYDVQPQGGVAGFRIDMAVRHPGA FT PGAYALGIECDGAMYHSSRAARDRDRLREEILRGLGWNLHRIWGTDWYRNRKDAQRRLR FT EAVEEACAADPYAPEPVSTPVPSTEQTPAEIAIVPVAESDRSEWSRPYRALGWEKPYEL FT KDTLSTAAGLPGVDLHDPAAKAVVAEVAHHIITMEGPIEEDVLIGRVRSAWLLDRSGQI FT VQSSVRDALSRLRKKNKAVRSGTVWDLPAREVTFARTPTPDFDRKKVSQVPSAERRIAL FT FGILSESPGMRREELARETARFFGWLRLGPDIKAAFDQDIEELIGGGLVTSGSSGLLPV FT EGSAG" FT CDS complement(207777..208070) FT /transl_table=11 FT /gene="SCO6642" FT /gene_synonym="SC4G2.16c" FT /product="hypothetical protein SC4G2.16c" FT /note="SC4G2.16c, questionable ORF, len: 97 aa" FT /db_xref="UniProtKB/TrEMBL:O86688" FT /protein_id="CAA20553.1" FT /translation="MASAQSGQQRFVRRRLQVDEDEDLSLIVRMQTGQFPAHPPTQISP FT SHRCSGACGILEEDAHAVGKRFQGFRIQPGYCASSDGDAFGGPVCRLIRPGG" FT CDS 208334..208888 FT /transl_table=11 FT /gene="SCO6643" FT /gene_synonym="SC4G2.17" FT /product="hypothetical protein SC4G2.17" FT /note="SC4G2.17, unknown, len: 184 aa; some similarity to FT TR:O26772 (EMBL:AE000847) hypothetical protein MTH676 FT (Methanobacterium thermoautotrophicum) (205 aa), fasta FT scores; opt: 260 z-score: 193.2 E(): 0.0016, 33.1% identity FT in 163 aa overlap. Contains Pfam match to entry PF00583 FT Acetyltransf, Acetyltransferase (GNAT) family, score 38.50, FT E-value 1.5e-07" FT /db_xref="GOA:O86689" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:O86689" FT /protein_id="CAA20554.1" FT /translation="MRTTDYTIRTATSADVPPARAVMLDTVYRDFRTGYVPRWHGDVID FT PAGAYLTPARHTLLVAVAADGEVVGTGALDSRGPAHPPNPPHVAERFPSGVTAQLRRIY FT VRPEHRRRGLARRLVDELLAFAVADGGYRAVYLHTDPAVTGAEPFWRSLAKVVHDERED FT AGGGQGIVHFEVPMAGWRGAR" FT misc_feature 208355..208801 FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 38.50, E-value FT 1.5e-07" FT RBS 208990..208993 FT /note="possible RBS upstream of SC4G2.18" FT CDS 208997..210508 FT /transl_table=11 FT /gene="SCO6644" FT /gene_synonym="SC4G2.18" FT /product="putative solute-binding lipoprotein" FT /note="SC4G2.18, probable solute-binding lipoprotein, len: FT 503 aa; similar to many members of the bacterial FT extracellular solute-binding protein family 5YLIB_ECOLI FT putative binding protein YLIB precursor (512 aa), fasta FT scores; opt: 364 z-score: 328.6 E(): 4.6e-11, 27.8% FT identity in 467 aa overlap. Contains N-terminal signal FT sequence with appropriately positioned PS00013 Prokaryotic FT membrane lipoprotein lipid attachment site and Pfam match FT to entry PF00496 SBP_bac_5, Bacterial extracellular FT solute-binding proteins, family 5, score 36.60, E-value FT 2.2e-08" FT /db_xref="GOA:O86690" FT /db_xref="InterPro:IPR000914" FT /db_xref="UniProtKB/TrEMBL:O86690" FT /protein_id="CAA20555.1" FT /translation="MRSHRRPRLLAPFLLVPLMAGCFASGGGDDSASGDGGDGDGARLR FT VALAFPPAENLSPYGADATLLSRLGVTEGLTSLDANGSAAPALAESWRRDGDRTWEFSL FT RDATFQDGGEVTPAAVAASLTHATDAEPAPAALAGVTLSAEAGGDRVVRITTAEPDPVL FT PLRLSSPSLAILSKGAYGKGSRVDPVGHATGPFELTKVNGATSASLDRFDDYWGGRAQA FT SGIDARFIADGTARANALRTGELDIAEAVPVAQAASLDEKTRRDTATTRTTSLLLNASS FT GPFKDAGLRAAARGALDTSVFAKDVYEGYGDPGAGVYGPAVTWAEGKRTAPVGRASAKK FT PGDGDTVNLATYDNRPELPEVAQVVKQQLEKAGFTVKLTVREYSRLEGDALDGKFDAFV FT LARNTLLDTGDPVAVLASDYTCDGGFNIAQLCDKGVDRAVADAEKIADTAKRQDAAMAA FT EARILGSDAVVPLVHQRIITGVAGSVQGVVLDPYERALVGTGTRR" FT misc_feature 209030..209062 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature 209216..209353 FT /note="Pfam match to entry PF00496 SBP_bac_5, Bacterial FT extracellular solute-binding proteins, family 5, score FT 36.60, E-value 2.2e-08" FT CDS 210512..212317 FT /transl_table=11 FT /gene="SCO6645" FT /gene_synonym="SC4G2.19" FT /product="putative transport system permease protein" FT /note="SC4G2.19, probable transport system permease FT protein, len: 601 aa; similar to many members of the oppBC FT family e.g. NIKB_ECOLI nickel transport system permease FT protein (314 aa), fasta scores; opt: 405 z-score: 322.1 FT E(): 1.1e-10, 33.4% identity in 290 aa overlap" FT /db_xref="GOA:O86691" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:O86691" FT /protein_id="CAA20556.1" FT /translation="MWQRVAGAGWRILLAVGLVCGVGLLPWLTRTDPAYTVLKARSAER FT EPTPEVLADIRRQLGIDGGPLHVLTGWLGGLVRGDAGRSWISGADVLPDVTRALGVSLL FT LMGVALLVAVLTAGLICARTLRLGARRRLGGRRGGGSLSAVLASLPEFLVASVLATVVG FT VQLGWLPALGWYGPQWTLLPALALGLPAGAVLGRLLDDLLPGAFGEPWALAAAARGLTG FT RSIARQALRRCVPALLPNFGLFVVGLTGGAVAVEQVFDIPGLGRTTLQAALAQDLPVLQ FT SGTLALVLLAGLATGATRVAARLLTGPALRDGALSSLHRPAPPAGGLLPLLYGALLLAV FT VGFGLTRDPLALDTGQRLRAPSLDHPFGTDALGRDLLARVGHGALDTLALAAAISAAAL FT LAGVLLGLVPRVSAPLVDTVNAVPPVLVALLVTAVAGSGAATPALAVGAVAWAPLAAHT FT SSLLRQERATLHITATKGLGAGPVHLLRHELLPAVVPPVLRHALLRLPGVALALASLGF FT LGLGAQPPSPEWGLLLAENQPYAERAPWAVLAPAAVLALLGALAVSAAGGLRRRPTRSS FT PRQTDAAGQRPVAEAEREPAGFGAR" FT RBS 212306..212309 FT /note="possible RBS upstream of SC4G2.20" FT CDS 212319..213629 FT /transl_table=11 FT /gene="SCO6646" FT /gene_synonym="SC4G2.20" FT /product="putative transport system permease protein" FT /note="SC4G2.20, probable transport system permease FT protein, len: 436 aa; similar to e.g. M. tuberculosis FT TR:O53861 (EMBL:AL022004) putative membrane transport FT protein MTV043.42 (419 aa), fasta scores; opt: 771 z-score: FT 629.6 E(): 8e-28, 37.6% identity in 396 aa overlap" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:O86692" FT /protein_id="CAA20557.1" FT /translation="MTSTPAPAGGRAGQVPGRRTAPFATLSPLLRLLILTQLAFNIGFF FT AVLPFLAEHLGQSVGMAGWLVGFVLGLRTFSQQGLFVVGGALADRYGIRPVVLAGCVLR FT IAGFAWLGFAERTWAVVSAVLLIGFAAALFSPAVESEVARQAVGWEEEGGGDRTRVLAL FT FTVAGQAGAFVGPLLGALLLAVDFRTACLAGAGVFVLVLAGHAWLLPQRVPGRAQVRMK FT GGARLVLRNRRFLALCCAYGAYLLAYNQLYLALPAEVERAAGSQAPLAWLFALSSLLVV FT IAQLPVTRWAGERLARRRSMVTGLVLIAVGFAVVGLARPAGWTGTGGLLPAAGFVVLLT FT LGQMLVAPVARAWVPDLAEDGRLGLYTGALSSVSGLIVLAGSSATGLLLDTGLPVAVPW FT LVLAAVPLVAAATLPRWPHRGAGATAPTPSTAGSGRS" FT CDS complement(213632..214426) FT /transl_table=11 FT /gene="SCO6647" FT /gene_synonym="SC4G2.21c" FT /product="putative integral membrane protein" FT /note="SC4G2.21c, possible integral membrane protein, len: FT 264 aa; similar to a hypothetical protein from Rhodobacter FT sphaeroides TR:O54078 (EMBL:AJ002398) (227 aa), fasta FT scores; opt: 493 z-score: 616.8 E(): 4.1e-27, 43.6% FT identity in 220 aa overlap. Also very weak similarity to FT PGSA_PSEFL (CDP-diacylglycerol--glycerol-3-phosphate FT 3-phosphatidyltransferase) (195 aa) E:0.0018, 30.8% FT identity in 146 aa overlap. Contains PS00379 CDP-alcohol FT phosphatidyltransferases signature" FT /db_xref="GOA:O86693" FT /db_xref="InterPro:IPR000462" FT /db_xref="UniProtKB/TrEMBL:O86693" FT /protein_id="CAA20558.1" FT /translation="MALINLNHTDDGYDAYDACPARSVQQETAVGAGAQILLLALLGTA FT IGMGTAGWLTGLAFAFASWAVLSRALHRSRLPSFGPANRVTLGRATLVGGVTALVADSF FT RSAPPLSLLVGLTAVALILDGVDGRVARRTGTSTPLGARFDMEVDAFLILVLSVYVALD FT LGPWVLLIGGMRYVFVAAARVWPWLTAPLPPSTARKTVAALQGVLLLLAGAELLPRPGN FT AGVVAVALGLLVWSFGRDVRWLWRRSRVPAAPVTAVRELVAQ" FT misc_feature complement(213980..214048) FT /note="PS00379 CDP-alcohol phosphatidyltransferases FT signature" FT RBS complement(214434..214438) FT /note="possible RBS upstream of SC4G2.21c" FT RBS 214523..214528 FT /note="possible RBS upstream of SC4G2.22" FT CDS 214536..214874 FT /transl_table=11 FT /gene="SCO6648" FT /gene_synonym="SC4G2.22" FT /product="hypothetical protein SC4G2.22" FT /note="SC4G2.22, unknown, len: 112 aa" FT /db_xref="UniProtKB/TrEMBL:O86694" FT /protein_id="CAA20559.1" FT /translation="MARMARAFWLEAPGRGAIREVELPVPGADEVLVRALFSGVSRGTE FT TLVFGGRVPENQYTAMRAPFQEGDFPGPVKYGYLGVGVGRRGRSGSSGAPCSVSTRTRP FT GTSSPPRP" FT CDS 214871..215545 FT /transl_table=11 FT /gene="SCO6649" FT /gene_synonym="SC4G2.23" FT /product="hypothetical protein SC4G2.23" FT /note="SC4G2.23, unknown, len: 224 aa" FT /db_xref="GOA:O86695" FT /db_xref="InterPro:IPR006076" FT /db_xref="UniProtKB/TrEMBL:O86695" FT /protein_id="CAA20560.1" FT /translation="MTPVPPSVPAGRAVLAGTVETAVNALWDAAPLIGDRVSVVGGGMV FT GCSVAALLARFPGVRVELVDADPARAEVAEALGAGFASPEDAAGDRDLVVHASATEAGL FT ARSLELLRPEGTVVELSWYGDRRVALPLGEAFHSRRLTLRGSQVGTVSPARATTRTYAD FT RLALALELLADPALDALVTGESAFAELPELMPRLASGALPALCHRIRYDEEDTGTDARS FT GA" FT RBS 215647..215651 FT /note="possible RBS upstream of SC4G2.24" FT CDS 215660..216058 FT /transl_table=11 FT /gene="SCO6650" FT /gene_synonym="SC4G2.24" FT /product="hypothetical protein SC4G2.24" FT /note="SC4G2.24, unknown, len: 132 aa" FT /db_xref="PDB:3D7J" FT /db_xref="UniProtKB/TrEMBL:O86696" FT /protein_id="CAA20561.1" FT /translation="MFSITVRDHIMIAHSFRGDVFGPAQRLHGATFLVDATFRREQLDE FT DNIVVDIGLATQELGAVVGALNYRNLDNEPDFAGVNTSTEFLAKVIADRLAERVHKGAL FT GEGARGLAGLTVTLHESHVAWASYERAL" FT CDS 216055..217293 FT /transl_table=11 FT /gene="SCO6651" FT /gene_synonym="SC5A7.01" FT /gene_synonym="SC4G2.25" FT /product="putative glycosyl transferase" FT /note="SC5A7.01, possible glycosyl transferase, partial FT CDS, len: >368 aa; similar to several hypothetical proteins FT e.g. YV12_MYCTU MTCY20G9.12 (480 aa), fasta sores; opt: 237 FT z-score: 252.3 E(): 8.1e-07, 29.9% identity in 278 aa FT overlap, and to WCAL_ECOLI putative colanic acid FT biosynthesis glycosyl transferase (406 aa), fasta sores; FT opt: 187 z-score: 194.8 E(): 0.0013, 27.8% identity in 237 FT aa overlap. Contains Pfam match to entry PF00534 FT Glycos_transf_1, Glycosyl transferases group 1, score FT 52.90, E-value 5.5e-14" FT /note="SC4G2.25, possible glycosyl transferase, partial FT CDS, len: >78 aa; overlaps and extends putative glycosyl FT transferase SC5A7.01" FT /db_xref="GOA:Q8CJM1" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q8CJM1" FT /protein_id="CAD55385.1" FT /translation="MTGTTAAGRTRLAHVPAQLPGTAQAQAQAQASIPVPVPVPRNGGI FT VPMSLRAVHFVMPGGVDDPAAPSGGNAYDRRVRLDLPGFGWRVRGLPVPGDWPRPDDAA FT RAELARVLRRLPDGAVVLLDGLVACGVPEVVVPEAERLRMAVLVHLPLGDETGLDPAVA FT AGLDARERTVLRAVPAVVATSDWAVRRLVSHHGLDPGRVHVAAPGADIAPLAPGTDGVS FT KLVCVAAVTPRKGQHRLVEALAAVSDLPWSCVCVGGLAQDPEYVDRLRSLIARHGLQER FT LVLAGPRAGADLDATYAAADLMVLTSYAETYGMAVTEALARGIPVLATDVGGLPEAVGR FT APDGGVPGILVPPEDPGALAAELRGWFGEPDVRRRLKAAARGRRAALNGWASTAQSLAG FT VLHRLPGEPRRAA" FT misc_feature 216844..217203 FT /note="Pfam match to entry PF00534 Glycos_transf_1, FT Glycosyl transferases group 1, score 52.90, E-value FT 5.5e-14" FT RBS 217279..217284 FT /note="possible RBS upstream of SC5A7.02" FT CDS 217290..218675 FT /transl_table=11 FT /gene="SCO6652" FT /gene_synonym="SC5A7.02" FT /product="hypothetical protein SC5A7.02" FT /note="SC5A7.02, unknown, len: 461 aa; contains 6 FT degenerate repeats of P(AT)ESAVPA" FT /db_xref="UniProtKB/TrEMBL:O88008" FT /protein_id="CAA19931.1" FT /translation="MNTSRPAPPTERTVPSPAESAVPASTESAVLARTGGAVPAPAESV FT GPSPAGGTGPVRLGPPDATGSRIAVVPVSGPARSDAGRPVERPASGLGGGPGEGRALPS FT ADRAEGGAARPATQRPGGADERTEDRAEQPSAGPVAEGQGQGRFGAGRPSAGSVADGLE FT QSSGERATVRLRGAPVREHPAEPPRYAPEWLRLREPADAAARAHDLLDPLRIRLADLPG FT RADGLVVHDLGCGTGSMGRWLAPLLDGAQHWVLHDRDPYLLHFAAAGAPHTAADGSRVT FT VETRRGDLAHLTPDALNGAGLVTASALLDVLTTEEVGKLAAACTAAGCPALLTLSVAGR FT VDLTPGHPLDTEITEAFNDHQRRTGMLGPGAVTVATEAFAGHGATVRAQPSDWRLGPGE FT AGLTAQWLRGWVGAAVEQRPELRARADRYLEERLAACAAGELRVVVHHTDLLALCRPTG FT GAP" FT repeat_region 217314..217457 FT /note="6x 24 bp repeats" FT RBS 218661..218665 FT /note="possible RBS upstream of SC5A7.03" FT CDS 218672..219874 FT /transl_table=11 FT /gene="SCO6653" FT /gene_synonym="SC5A7.03" FT /product="hypothetical protein SC5A7.03" FT /note="SC5A7.03, probable integral membrane protein, len: FT 400 aa. Note 63 aa overlap with convergent downstream ORF. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:O88009" FT /protein_id="CAA19932.1" FT /translation="MSAPTLPTVSTVPAAVPPTPVRPHAPTGVAAPRRRALRAHLGTLA FT GTAVLAVLLWRLGTGAFLDGLRRIDGPAVLAALGIGLVTTVFSAWRWALVARGLRIRLP FT LAAAVADYYRALFLNAALPGGVLGDVHRAVRHGRSTGDLGRGVRAVVLERVAGQLALIG FT AGAGVLLTMPSPVRAEVRHLAPLVALALAGALAVVLALRWNRAPARRGRAVRTALGEAR FT HGLLSRRNLPGIVLSSAIVLAGHLTMFVVAARVAGSAASVAVLTPLAVLALLAMGLPLN FT VGGWGPREGVTAWAFGAAGLGAGTGLGVAVVYGVLSLVASLPGVVVLVGRRYAARYPRS FT PSEPSEASESSEPSDVDGVPAVSAVSSATYSPKESARLSSSSFPFSADPSEGRPMTPES FT V" FT CDS complement(219679..220500) FT /transl_table=11 FT /gene="SCO6654" FT /gene_synonym="SC5A7.04c" FT /product="conserved hypothetical protein" FT /note="SC5A7.04c, unknown, len: 273 aa; some similarity to FT hypothetical proteins and to Pseudomonas TR:Q52548 FT (EMBL:D45424) creatinine amidohydrolase (259 aa), fasta FT sores; opt: 193 z-score: 273.1 E(): 5.6e-08 27.3% identity FT in 238 aa overlap. Note 63 aa overlap with convergent FT downstream ORF" FT /db_xref="InterPro:IPR003785" FT /db_xref="UniProtKB/TrEMBL:O88010" FT /protein_id="CAA19933.1" FT /translation="MKGRAGMDVSLVPADTSDDVRERGSGLPRQVAVLPVGSFEQHGPY FT LPLATDTLVACAVARAVADAYPVHLLPPVTIGCSHEHADWPGTVSISAVTLHAVVRDIA FT DSLRRSGVGALVVVNGHGGNYVLGNVVQESSARGERMALFPAAEDWETARRRAGVVTSL FT LTDMHAGEIETSILLHKHPELVRPGYEAADFVADDRRHLLSLGMSAYTDSGVIGRPSLG FT SAEKGKELLESLADSFGEYVALLTAETAGTPSTSEGSDDSEASDGSDGERG" FT RBS 220520..220523 FT /note="possible RBS upstream of SC5A7.05" FT CDS 220536..221201 FT /transl_table=11 FT /gene="SCO6655" FT /gene_synonym="SC5A7.05" FT /gene_synonym="ribA2" FT /product="GTP cyclohydrolase II" FT /note="SC5A7.05, ribA2, GTP cyclohydrolase II, len: 221 aa; FT highly similar to the C-terminus of many RibA genes where FT the GTP cyclohydrolase activity is, e.g. GCH2_BACSU GTP FT cyclohydrolase II (EC 3.5.4.25) (398 aa), fasta sores; opt: FT 656 z-score: 960.9 E(): 0, 53.1% identity in 196 aa overlap FT and to SW:GCH2_ARATH (EMBL:D45165) Arabidopsis thaliana GTP FT cyclohydrolase II (EC 3.5.4.25) 245 aa; fasta scores: opt: FT 656 Z-score: 760.1 E(): 1.1e-34; 51.832% identity in 191 aa FT overlap" FT /db_xref="GOA:O88011" FT /db_xref="InterPro:IPR000926" FT /db_xref="UniProtKB/Swiss-Prot:O88011" FT /protein_id="CAA19934.1" FT /translation="MTEKIGVLGKKTTQRTDVERIVVTPLPTVYGKFRAFGYFDHERGD FT EQVALVHGDLGAEDVLTRLHSECLTGDAFGSQHCECGAQLASALRQVADAGSGIVVYLR FT GHEGRGIGLLAKLRAMALQAEGLDTVEANLALGLPVDARDYGVAARILDDLGVRSVRLM FT SNNPRKREALVRHGIRVAEQVPLLIPPCESNITYLRTKRERLDHHLPHLDAAMAHVSS" FT CDS complement(221232..222461) FT /transl_table=11 FT /gene="SCO6656" FT /gene_synonym="SC5A7.06c" FT /product="conserved hypothetical protein SC5A7.06c" FT /note="SC5A7.06c, unknown, len: 409 aa; similar to several FT hypothetical protein e.g. Y07V_MYCTU MTCY02B10.31C (377 FT aa), fasta sores; opt: 675 z-score: 725.7 E(): 3.5e-33, FT 40.9% identity in 340 aa overlap, and more distantly to FT several penicillin binding proteins e.g. PBPE_BACSU FT penicillin-binding protein 4* (451 aa), fasta sores; opt: FT 148 z-score: 268.0 E(): 1.1e-07, 24.9% identity in 350 aa FT overlap" FT /db_xref="HSSP:1CI9" FT /db_xref="InterPro:IPR001466" FT /db_xref="UniProtKB/TrEMBL:O88012" FT /protein_id="CAA19935.1" FT /translation="MPPLRQEVEAGAAGLDPGALARLDLHFARQVDEGRLPGFLVAVAR FT GGRVAHLTVHGLRDVAAGLPVTADTLWRIYSMTKPVTSVAVLTLVEEGRLALDDPVDRY FT LPAFAEPRVYVGGTGENVVTRPATGPVRVRHLMTHTAGLTFGFYRTHPVDALYRAAGVE FT SSVRPGADLAETVDLYASLPLQFDPGTEWNYSVASNVLGRLVEVVSGQPLDVFCAERIF FT GPLGMTDTGFHVADAQAGRLAELYGETEDGGIAPVPGLPLLGRPRFLSGSGGLASSAYD FT VHRFAELLRRRGELDGVRLLAPATVDLMTRNHLPGDADLRSFGSRPAHDERGNDGVGFG FT LGVSVVTDPSRTRSPSGLGTYGWSGVATTTFWVDPGRDLTVQFMTQVRPRSSHAVYPDL FT KRLVHEALTD" FT RBS complement(222472..222477) FT /note="possible RBS upstream of SC5A7.06c" FT CDS complement(222553..224136) FT /transl_table=11 FT /gene="SCO6657" FT /gene_synonym="SC5A7.07c" FT /product="putative membrane protein" FT /note="SC5A7.07c, putative membrane protein, len: 527 aa; FT similar to two consecutive genes downstream of HISX_STRCO FT S. colelicolor histidinol dehydrogenase; TR:Q53931 and FT TR:Q53930, fasta scores; E(): 1.4e-07, 34.3% identity in FT 213 aa overlap and E(): 1.1e-06, 32.3% identity in 223 aa FT overlap. Contains possible hydrophobic membrane spanning FT region at C-terminal domain" FT /db_xref="UniProtKB/TrEMBL:O88013" FT /protein_id="CAA19936.1" FT /translation="MGGPESALTCSAGSGQSPSLMEINDLTPAESRLWRAFASGTDVDF FT RATNPPAPGSSATDPSGGADPSGADSDDPARGDTWGPERTVRASVLRSLLLDGPREDGR FT VAALSLAGARVTGRLDVQYATVDHPVRLRHCHFDEAPRFYGARLRELNLSESVLPGLIS FT HAVRVEGVLRLTRARFSGTVRLAGAEVTGSLYLESTRIEAPDTEGPVLQLNQAVLGADL FT WAPGLRTAGEVRLTGARVAGTVNLNDAVLDRPGGTAVHAETLATEADVLLRRADVRGRL FT ELRGARIPGRLDLSHARLANAGNTALRASSCVIGELWLREGPAVQGALNLRRAQVDVLF FT LQPEVVPAWVQLNDLTYTSLIPHEPAGRRLPMLEKGDRYLPFTYEQLTAAYRRIGDDDA FT ARLVQLAKQRRRRRTLPWYGRLWGHLQDIAVGYGFRPLRAGGWLLSLLAVGSVVYGLHH FT PPPLKPQEAPGFNPVFYTLDLLLPVISFGQESAFSPQGGYQTLSYVLVITGWILATTVI FT TGLTRTVSRQ" FT CDS complement(224148..225029) FT /transl_table=11 FT /gene="SCO6658" FT /gene_synonym="SC5A7.08c" FT /product="6-phosphogluconate dehydrogenase" FT /note="SC5A7.08c, probable 6-phosphogluconate FT dehydrogenase, len: 293 aa; similar to many eukaryotic e.g. FT 6PGD_BACSU 6-phosphogluconate dehydrogenase, FT decarboxylating (468 aa), fasta sores; opt: 445 z-score: FT 616.2 E(): 4.4e-27, 36.6% identity in 287 aa overlap.also FT highly similar to S. coelicolor 6-phosphogluconate FT dehydrogenase (EMBL:L27063) TR:Q53917 (291 aa), fasta FT sores; opt: 1654 z-score: 2054.7 E(): 0, 83.4% identity in FT 289 aa overlap. Contains PS00065 D-isomer specific FT 2-hydroxyacid dehydrogenases NAD-binding signature and Pfam FT match to entry PF00393 6PGD, 6-phosphogluconate FT dehydrogenases, score 169.20, E-value 6.9e-47" FT /db_xref="GOA:O88014" FT /db_xref="HSSP:2PGD" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:O88014" FT /protein_id="CAA19937.1" FT /translation="MQIGLVGLGKMGGNMRERLRNAGHTVVGYDTNPDRADVDSLVELV FT DRLERPRAVWVMVPAGGATQHVIDQLATLLKPGDTVIDGGNSRWTDDEKHAEELGKRGI FT NFVDAGVSGGVWGLKNGYALMVGGDKETVDDLKPVFDALKPDGPYGYVHAGKVGAGHFS FT KMVHNGIEYAMMQAYAEGWELLEKVDSVDNVREVFRSWQEGTVIRSWLLDLAVNALDDD FT HHLEKLRGYADDSGEGRWTVEAAIDNAVPLPAITASLFARFASRQEDSPQMKMVAALRN FT QFGGHAVESAKK" FT misc_feature complement(224235..224912) FT /note="Pfam match to entry PF00393 6PGD, 6-phosphogluconate FT dehydrogenases, score 169.20, E-value 6.9e-47" FT misc_feature complement(224940..225023) FT /note="PS00065 D-isomer specific 2-hydroxyacid FT dehydrogenases NAD-binding signature" FT CDS complement(225031..226683) FT /transl_table=11 FT /gene="SCO6659" FT /gene_synonym="SC5A7.09c" FT /gene_synonym="pgi" FT /product="glucose-6-phosphate isomerase" FT /note="SC5A7.09c, pgi, glucose-6-phosphate isomerase, len: FT 550 aa; highly similar to many e.g. G6PI_ECOLI FT glucose-6-phosphate isomerase (EC 5.3.1.9) (549 aa), fasta FT sores; opt: 1878 z-score: 1900.7 E(): 0, 53.6% identity in FT 545 aa overlap. Contains PS00174 Phosphoglucose isomerase FT signature 2 and Pfam match to entry PF00342 PGI, FT Phosphoglucose isomerase, score 897.30, E-value 4.4e-266" FT /db_xref="GOA:O88015" FT /db_xref="HSSP:1IAT" FT /db_xref="InterPro:IPR018189" FT /db_xref="UniProtKB/Swiss-Prot:O88015" FT /protein_id="CAA19938.1" FT /translation="MSDTPKLNQRPEWTALADHAKGTLPHPDLRELFAQDPGRAERYVV FT RVGDLRIDYSKHLVTDETLALLQELAAATGVSGLRDAMFRGERINITEDRAVLHTALRA FT PRDAVIEVDGENVVPQVHAVLDKMAGFADRVRSGEWTGHTGRRIRNVVNIGIGGSDLGP FT AMAYEALRAFTDRSLTLRFVSNVDGADLHEAVRDLDPAETLFIIASKTFTTIETITNAT FT SARSWLLDGLGGDEKAVAKHFVALSTNAEKVADFGIDTANMFEFWDWVGGRYSFDSAIG FT LSLMIAIGPDRFREMLDGFRIVDEHFRNAEAPANAPLLLGLLGVWYGDFLGAQSHAVLP FT YSHYLSKFTAYLQQLDMESNGKSVDREGNPVQWQTGPVVWGTPGTNGQHAYYQLIHQGT FT KLIPADFIGFARPVDELSEELKAQHDLLMANFFAQTQALAFGKTPDEVRAEGVPEELVP FT HKTFRGNHPTTTVLAAELTPSVLGQLIALYEHKVFVQGAIWNIDSFDQWGVELGKVLAK FT RVEPALTEGADVPGLDPSTAALVAAYRELKEVH" FT RBS complement(225041..225045) FT /note="possible RBS upstream of SC5A7.08c" FT misc_feature complement(225064..226527) FT /note="Pfam match to entry PF00342 PGI, Phosphoglucose FT isomerase, score 897.30, E-value 4.4e-266" FT misc_feature complement(225145..225198) FT /note="PS00174 Phosphoglucose isomerase signature 2" FT CDS complement(226676..227611) FT /transl_table=11 FT /gene="SCO6660" FT /gene_synonym="SC5A7.10c" FT /product="hypothetical protein SC5A7.10c" FT /note="SC5A7.10c, unknown, len: 311 aa; similar to a FT hypothetical protein from M. tuberculosis TR:O06813 FT (EMBL:Z95844) MTCY493.08 (303 aa), fasta scores; opt: 847 FT z-score: 1016.2 E(): 0, 47.7% identity in 304 aa overlap. FT Also some similarity to OPCA_SYNP7 putative oxpp cycle FT protein OpCA (which may be involved in functional assembly FT of glucose 6-phosphate dehydrogenase) (444 aa), fasta FT scores; opt: 149 z-score: 218.9 E(): 5.9e-05, 32.4% FT identity in 142 aa overlap. Note that both of these FT proteins are downstream of glucose-6-phosphate FT dehydrogenase genes" FT /db_xref="InterPro:IPR019297" FT /db_xref="UniProtKB/TrEMBL:O88016" FT /protein_id="CAA19939.1" FT /translation="MRIDLTDTTASKINKALVQGRRAIGTPAVGMVLTLVIVTDEENAY FT DATKAAEEASHEHPSRTLVVIKRHPRNLRDRTRSHLDAEVRVGSEAGTGETVVLRTYGE FT VSEHADSVVLPLLLPDAPVVVWWPVEAPDNPAKDPLGALAQRRITDLYTVERPMEVLER FT RVRAYAPGDTDLAWTRLTLWRSMLAAALDQARVPVTSAVVEAEADNPAAELLARWMEAR FT LGVRVDRVVTDGPVVTAVRLGTANGEIVVDRPEGPLATMTLPGQPSRSVALKVRPTSEL FT IAEELRRLDADEMYAVALRGKAGKETPVHV" FT RBS complement(226694..226699) FT /note="possible RBS upstream of pgi" FT CDS complement(227608..229386) FT /transl_table=11 FT /gene="SCO6661" FT /gene_synonym="SC5A7.11c" FT /gene_synonym="zwf" FT /product="glucose-6-phosphate 1-dehydrogenase" FT /note="SC5A7.11c, zwf, probable glucose-6-phosphate FT 1-dehydrogenase, len: 592 aa; similar to many, e.g. FT G6PD_ECOLI glucose-6-phosphate 1-dehydrogenase (EC FT 1.1.1.49) (491 aa), fasta scores; opt: 1145 z-score: 1213.9 FT E(): 0, 43.1% identity in 487 aa overlap. Alternative start FT site at aa 83 predicted by database similarity. Contains FT PS00069 Glucose-6-phosphate dehydrogenase active site and FT Pfam match to entry PF00479 G6PD, Glucose-6-phosphate FT dehydrogenase, score 730.30, E-value 1.1e-236" FT /db_xref="GOA:O88017" FT /db_xref="HSSP:1QKI" FT /db_xref="InterPro:IPR019796" FT /db_xref="UniProtKB/TrEMBL:O88017" FT /protein_id="CAA19940.1" FT /translation="MSEELPAGAPQETKATKEAKETRTAQEAAGPLHAEEAEEARAAEA FT AKASGRAKAPRGAKKSATNRAAKEAKGKGAAGEGVEPVAPLDWSNPLRDPQDRRLPRIA FT GPSGLVIFGVTGDLSRKKLMPAVYDLANRGLLPPGFSLVGFARRDWEDQDFAEVVHDAV FT REHARTPFREEVWQQLSEGMRFIPGDFDDDNAFEQLRKAVEELDASRGTSGNYAFYLSV FT PPKFFPKVVQQLKKHGLTDAPAGSWRRAVIEKPFGHDLDSARDLNALVHEVFDPEQVFR FT IDHYLGKETVQNILALRFANQMYEPIWNRSYVDHVQITMAEDIGIGGRAGYYDGIGAAR FT DVIQNHLLQLMALTAMEEPAAFDARSLLTEKLKVLRAVRLPDDLGEHTVRGQYAGGWQG FT GAQVPGYLEEEGIDPASTTDTYAAIKLGIDNRRWAGVPFYLRTGKRLGRRVTEIAVVFQ FT RAPHSPFDSTATEELGENAIVIRVQPDEGMTVRFGSKVPGTSMEIRDVSMDFAYGESFT FT ESSPEAYERLILDVLLGDANLFPRHQEVEESWRILDPIEEYWASHDKPAQYASGGWGPR FT EADEMLARDGRSWRRP" FT misc_feature complement(227662..229059) FT /note="Pfam match to entry PF00479 G6PD, FT Glucose-6-phosphate dehydrogenase, score 730.30, E-value FT 1.1e-236" FT misc_feature complement(228520..228540) FT /note="PS00069 Glucose-6-phosphate dehydrogenase active FT site" FT CDS complement(229383..230528) FT /transl_table=11 FT /gene="SCO6662" FT /gene_synonym="tal1" FT /product="transaldolase" FT /note="SC5A7.12c, tal1, probable transaldolase, len: 381 FT aa; highly similar to those from Mycobacteria e.g. FT TR:O06812 (EMBL:Z95844) transaldolase (EC 2.2.1.2) (373 FT aa), fasta scores; opt: 1391 z-score: 2065.3 E(): 0, 61.2% FT identity in 369 aa overlap, and from Eukaryotes e.g. potato FT TR:O04894 (EMBL:U95923) transaldolase (EC 2.2.1.2) (438 FT aa), fasta scores; opt: 953 z-score: 1323.1 E(): 0, 47.1% FT identity in 357 aa overlap. Contains PS01054 Transaldolase FT signature 1 and PS00958 Transaldolase active site" FT /db_xref="GOA:O88018" FT /db_xref="InterPro:IPR014634" FT /db_xref="UniProtKB/Swiss-Prot:O88018" FT /protein_id="CAA19941.1" FT /translation="MITVTEATATAGALQRLADQGVSVWLDDLSRRRIESGNLAELIRT FT KNVVGVTTNPSIFQAAIGSGEGYEEQLADLATRGVTVDEAVRMMTTADVRAAADVLRGV FT YDASGGRDGRVSIEVDPRLAHDTAATVAEARQLSWLVDRPNVMIKIPATKAGLPAITEV FT IGAGISVNVTLIFSLERYREVMDAYLAGLEKAQAAGIDLAGIHSVASFFVSRVDSEIDK FT RLSLLGTEEALGLRGRAALANARLAYEAYENVFAGDRFTALAGARANAQRPLWASTGVK FT DPAFRDTLYVEELVAPGTVNTMPEATLDAAADHGDVRGDTVTGGYAQARADLAAVERLG FT VSYDEVVEQLEQEGVAKFEAAWQELLAAVTKSLDSKGVDGE" FT RBS complement(229397..229400) FT /note="possible RBS upstream of zwf" FT misc_feature complement(230040..230093) FT /note="PS00958 Transaldolase active site" FT misc_feature complement(230355..230381) FT /note="PS01054 Transaldolase signature 1" FT CDS complement(230592..232688) FT /transl_table=11 FT /gene="SCO6663" FT /gene_synonym="tktB" FT /product="transketolase B" FT /note="SC5A7.13c, tktB, probable transketolase, len: 698 FT aa; highly similar to many e.g. TKT2_ECOLI transketolase 2 FT (EC 2.2.1.1) (667 aa), fasta scores; opt: 1191 z-score: FT 1912.7 E(): 0, 46.0% identity in 683 aa overlap. Contains FT PS00802 Transketolase signature 2 and Pfam match to entry FT PF00456 transketolase, Transketolase, score 1163.10, FT E-value 0" FT /db_xref="GOA:O88019" FT /db_xref="HSSP:1QGD" FT /db_xref="InterPro:IPR005475" FT /db_xref="UniProtKB/TrEMBL:O88019" FT /protein_id="CAA19942.1" FT /translation="MSTQSSKQTVDGADRFEWTELDRRAVDTARILAADAVQKVGNGHP FT GTAMALAPAAYTIFQKVMRHDPADPEWTGRDRFVLSPGHTSLTLYTQLFLAGYEVELDD FT LKAFRTHGSRTPGHPEYGHTAGVETTTGPLGQGVANAVGMAMAARYERGLFDPEAPEGE FT SPFDHTIWAIVSDGDLQEGVSAEASSLAGHQKLGNLVFLYDDNHISIEGDTVTAFSEDV FT LKRYEAYGWHTQRVEPAESGDVDVRALHAAMTAAKAETGRPSIIAMRTIIAWPAPNAQN FT TEASHGSALGADEIAATKRVLGFDPERSFEVADEVLAHTRRALDRGAEAHAAWDKRIAA FT WRDAAPERAALFDRVVAGRLPEGWENALPVFETGKAVATRAASGKVLQALGPVLPELWG FT GSADLAGSNNTTIDKTSSFLPGGNPLPGADPYGRTVHFGIREFSMAAEMNGIALHGNTR FT IYGGTFLVFSDYMRNAVRMSALMQLPVTYVWTHDSIGLGEDGPTHQPVEHLASLRAIPG FT LNVVRPADANETATVWAEILRRHSTHPAPHGLALTRQGVPTYAPNPDAARGGYVLADAS FT TGAPDVVLIATGSEVQLAMAARETLEAEGTATRVVSMPSVEWFEEQPRAYRESVLPPSV FT RARVAVEAGIGLTWHRFVGDAGRIVSLEHFGASADAKTLFSEFGFTAGHVAAAARDSLA FT AARG" FT misc_feature complement(230634..232613) FT /note="Pfam match to entry PF00456 transketolase, FT Transketolase, score 1163.10, E-value 0" FT misc_feature complement(231150..231200) FT /note="PS00802 Transketolase signature 2" FT misc_feature complement(232170..232173) FT /note="end of true overlap with cosmid 4G2" FT RBS complement(232699..232702) FT /note="possible RBS upstream of tkt" FT misc_feature 232704..232707 FT /note="end of true overlap with cosmid 6G3" FT RBS 232837..232840 FT /note="possible RBS upstream of SC5A7.14" FT CDS 232846..233751 FT /transl_table=11 FT /gene="SCO6664" FT /gene_synonym="SC5A7.14" FT /product="putative transcriptional regulator" FT /note="SC5A7.14, probable transcriptional regulator, len: FT 301 aa; some similarity to many members of the araC family, FT e.g. MMSR_PSEAE MmsAB operon regulatory protein (307 aa), FT fasta scores; opt: 113 z-score: 251.4 E(): 9.2e-07, 25.4% FT identity in 303 aa overlap. Contains probable FT helix-turn-helix motif from aa 216-237 (Score 1252, +3.45 FT SD) and Pfam match to entry PF00165 HTH_2, Bacterial FT regulatory helix-turn-helix proteins, araC family, score FT 63.30, E-value 5.3e-15" FT /db_xref="GOA:O88020" FT /db_xref="InterPro:IPR018060" FT /db_xref="UniProtKB/TrEMBL:O88020" FT /protein_id="CAA19943.1" FT /translation="MADERSQDGGDGIRTFPFPVDLSLLGVGMQVGPMGDGRTWHAQAP FT LHRVHRIDFHIVMLFTGGPVRHMIDFAEYEASAGDLLWIRPGQVHRFAPEGEYRGTVLT FT MQPGFLPRATVEATGLYRYDLPPLLHPDEARLAGLTAALEQLRREYEDATTLPLSLHTA FT VLRHTLSAFLLRLAHLAAGSARAARQGRAEAPGDSTFVLFRDAVERGFATNHSVSAYAD FT ALGYSRRTLVRAVRAATGETPKGFIDKRVVLEAKRLLAHTEMPIGRVGAAVGFPDAANF FT SKFFQQHTDQTPAAFRAELR" FT misc_feature 233485..233745 FT /note="Pfam match to entry PF00165 HTH_2, Bacterial FT regulatory helix-turn-helix proteins, araC family, score FT 63.30, E-value 5.3e-15" FT CDS complement(233831..235231) FT /transl_table=11 FT /gene="SCO6665" FT /gene_synonym="SC5A7.15c" FT /product="putative secreted glucosidase" FT /note="SC5A7.15c, probable secreted glucosidase, len: 466 FT aa; similar to e.g. TR:G2981143 (EMBL:AF052745) FT beta-1,3-glucanase II from Oerskovia xanthineolytica (435 FT aa), fasta scores; opt: 313 z-score: 413.3 E(): 8.7e-16, FT 37.0% identity in 435 aa overlapand XYND_BACPO FT endo-1,4-beta-xylanase D precursor (Bacillus polymyxa) (635 FT aa), fasta scores; opt: 339 z-score: 315.2 E(): 2.6e-10, FT 27.5% identity in 447 aa overlap" FT /db_xref="GOA:O88021" FT /db_xref="HSSP:1O8P" FT /db_xref="InterPro:IPR013320" FT /db_xref="UniProtKB/TrEMBL:O88021" FT /protein_id="CAA19944.1" FT /translation="MSQTSGNPPRRRPLRRALVAVIGTLGLAAAAATVTGPSAGAAVPP FT PPSGWTQVFADDFDGAAGSGVNTANWQYDTGTSYPGGPANWGTGEIETMTSSPSNVSLD FT GGGNLRITPQRDGAGNWTSGRIETKRADFEPPAGGKLRVEARIQVPNVTGAAAKGYWPA FT FWMLGAPYRGNYWNWPGVGEIDIMENTQGLNTVWSTLHCGTSPGGPCNETSGIGGNTPC FT PGATCQAGFHTYRVEWDRSTSVEEIRFSVDGNNFHTVRANQVDATTWANATNHGYFIIL FT NVAMGGGFPDAFGGGPDGGTQPGHSMLVDYVQVLSAGGSGTTPPPTGGDRDAYGAIEAE FT SYDAQSGTMTEGTSDSGGGSNLGALANGDWVQYKGVEFGSSAATQFKARVASGAAAGVS FT GLVEVRLDSRTSTPVGSFAVGNTGGWQSWRTIPANIASVTGTHDVYLTFTSGQSADFVN FT VNWFGFGH" FT RBS complement(235242..235245) FT /note="possible RBS upstream of SC5A7.15c" FT CDS complement(235534..237651) FT /transl_table=11 FT /gene="SCO6666" FT /gene_synonym="SC5A7.16c" FT /product="putative integral membrane protein" FT /note="SC5A7.16c, probable integral membrane protein len: FT 705 aa; similar to many hypothetical membrane proteins e.g. FT M. tuberculosis TR:E1299723 (EMBL:AL021928) MMPL3 (944 aa), FT fasta scores; opt: 482 z-score: 907.8 E(): 0, 33.3% FT identity in 744 aa overlap" FT /db_xref="GOA:O88022" FT /db_xref="InterPro:IPR000731" FT /db_xref="UniProtKB/Swiss-Prot:O88022" FT /protein_id="CAA19945.1" FT /translation="MLSTLARAATRRPLTVMLLWGLFLLLGFGLGTGVFGRLSDDVPDV FT PGTESQVAAEHLDGLDPAGDSITGVVEAAAVADPAVRAEVRRAVADLREVAGVAEVPDP FT YATPGTVAEDGRALVVSVTLEGGLDDDAEEAAVDDAADRLHGIDGSAVSGVHVSGGPLL FT GQQLGERAQEDVKNAELISLPVVLVLLLVVFGGLRAAGLPLLVAVAGIAGAFLALFGFS FT HVTDISVYAIQVTTMLGLGLAVDYALLMLVRFREERRHIPDVVEAVHRTVAAAGRTVLF FT SGLTVAVSLAGLLVFPSTFLRSMGLAVAAVVVVDMLAALTLLPALLTRFGGRIPPAKAR FT PEEEGRLFARLARFAARRRVAVLAVAVPALLVVALPVTGMSINLGDARQLPKSTEARQL FT YDAIEAHFPPGTGVSPVTVVLRPGTDTATADRIGAIAGGTTVRDLPGGTTVLELPAGGA FT ADGPAATELVERVRDLRGDAPVQVTGSAAQLVDFRQMLADRAPWAALTVLTGIFVLLFA FT FTGSVLLPLRTVATTLLSLGAALGAVVWVFQDGHLAGPIGAEGLGALSLTAPPLIIAIA FT FGLAMDYELFILARMREARERTGDDREAVVTGLRRSGRVVTCAALLLAVVFGAFMTGGF FT SPILQIGLGLTLAVLIDATVVRMLLVPATMALLGRHAWWAPKPLRRAHERFGVREEAPG FT PAPAPPQPAAR" FT RBS complement(237656..237660) FT /note="possible RBS upstream of SC5A7.16c" FT CDS complement(237798..238466) FT /transl_table=11 FT /gene="SCO6667" FT /gene_synonym="SC5A7.17c" FT /product="putative two-component regulator" FT /note="SC5A7.17c, probable two-component regulator, len: FT 222 aa; highly similar to many e.g. DEGU_BACSU FT transcriptional regulatory protein DegU (229 aa), fasta FT scores; opt: 561 z-score: 630.7 E(): 7e-28, 44.0% identity FT in 225 aa overlap. Contains PS00622 Bacterial regulatory FT proteins, luxR family signature, probable helix-turn-helix FT motif from aa 173 to 194 (Score 1001, +2.60 SD) and Pfam FT matches to entry PF00072 response_reg, Response regulator FT receiver domain, score 124.10, E-value 2.7e-33 and entry FT PF00196 GerE, Bacterial regulatory proteins, luxR family, FT score 86.30, E-value 6.1e-22" FT /db_xref="GOA:O88023" FT /db_xref="HSSP:1FSE" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:O88023" FT /protein_id="CAA19946.1" FT /translation="MSVRVVVADDQELVRSGFSMILEAQPDIEVVAEAGDGAEAVAAVE FT RYAPDVLLLDIRMPVMDGLDAARRVCARSACKVVMLTTFDLDEYVYEALYAGASGFLLK FT DVRRDDLVHAVRVVAAGDSLLAPAVTRRLVADIVRRRREEAAADVTPQRLEVLTAREVE FT TLRLLARGLSNSEIATTLFVSEHTVKTHVSNVLGKLGLRDRVQAVICAYETGLVAPGSP FT " FT misc_feature complement(237810..238007) FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 86.30, E-value FT 6.1e-22" FT misc_feature complement(237873..237956) FT /note="PS00622 Bacterial regulatory proteins, luxR family FT signature" FT misc_feature complement(238122..238460) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 124.10, E-value 2.7e-33" FT CDS complement(238463..239680) FT /transl_table=11 FT /gene="SCO6668" FT /gene_synonym="SC5A7.18c" FT /product="putative two-component sensor" FT /note="SC5A7.18c, probable two-component sensor, len: 405 FT aa; similar in C-terminus to many e.g. NARQ_ECOLI nitrate FT /nitrite sensor protein narQ (566 aa), fasta scores; opt: FT 230 z-score: 252.5 E(): 7.9e-07, 30.7% identity in 202 aa FT overlap. N-terminus contains six probable trans-membrane FT domains. Contains probable coiled-coil from 168 to 197" FT /db_xref="GOA:O88024" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:O88024" FT /protein_id="CAA19947.1" FT /translation="MSARSPLSSPLAPVLARLRTASPYAVDAAVAALVLFAVSLQWLFP FT DEGDDPLSWRGWLLGAGTAVPLVWRRAAPFATACAVSVATPAQAVHHAPPPDLMYGGFV FT VLYTLAALARPWQRRVMLAGWLAGVAATISHKEDAEPFEYAFQLLSIVCAYALGSLTRT FT QRAYTAELEDRARHLERERAADTARATAQERARIARDMHDILAHAVSLMVVQAEAGPVV FT VRSDPARAEAAFDAIATAGRDAMTQLRRILGVLKEEEREPGPRRLPQPGLTALPGLVRR FT VGESAGLRVELRTTGEPGALPPDTEAAAYRIVQEALTNTVKHAYASCAVVGLDWAEDGV FT TLTVTDDGRGPAPGDGTGGGGHGLIGIRERAAACGGEAVTGGGPDGGFRVVVRLPAAAV FT RRTALG" FT RBS complement(239686..239690) FT /note="possible RBS upstream of SC5A7.18c" FT CDS complement(239712..240506) FT /transl_table=11 FT /gene="SCO6669" FT /gene_synonym="SC5A7.19c" FT /product="putative transcriptional regulator" FT /note="SC5A7.19c, probable transcriptional regulator, len: FT 264 aa; similar to members of the iclR family e.g. FT GYLR_STRCO glycerol operon regulatory protein (254 aa), FT fasta scores; opt: 277 z-score: 318.0 E(): 1.8e-10, 31.4% FT identity in 245 aa overlap. Contains probable FT helix-turn-helix motif from aa 28-49 (Score 1240, +3.41 FT SD)" FT /db_xref="GOA:O88025" FT /db_xref="InterPro:IPR005471" FT /db_xref="UniProtKB/TrEMBL:O88025" FT /protein_id="CAA19948.1" FT /translation="MTAPATPTAPDRLLAVLAAFDHAHPALSLTDISRRAGLSLTTAHR FT LVGALTRWGALERDGAGVYHVGLRSWEIAALAPRGLALRQVAWPYLEDLYEATHENVQL FT AVRDGGEVVYIEWLAARSSIGVHIRVGARWPLHATGVGLALLAHGEPEFQEAYRTGPLA FT SFTPYTITDPVRLRRVLAEVRRTGAAVSDRQITDDALSVAAPVHGPDGTVTAAVSVVVP FT HAGAQVPALVPAVRLAARGISRALGWRPNIPRTGEDGPPYSS" FT RBS 240635..240638 FT /note="possible RBS upstream of SC5A7.20" FT CDS 240645..241970 FT /transl_table=11 FT /gene="SCO6670" FT /gene_synonym="SC5A7.20" FT /product="putative glucosidase" FT /note="SC5A7.20, probable glucosidase, len: 441 aa; similar FT to e.g. CELF_ECOLI 6-phospho-beta-glucosidase (450 aa), FT fasta scores; opt: 537 z-score: 628.7 E(): 8.8e-28, 31.8% FT identity in 456 aa overlap" FT /db_xref="GOA:O88026" FT /db_xref="InterPro:IPR019802" FT /db_xref="UniProtKB/TrEMBL:O88026" FT /protein_id="CAA19949.1" FT /translation="MLGGGGFRVPLVYGALLGDRGEGRVSDVVLHDLDPARLTAVTRVL FT AEQAAGVPDAPTVTATTDLDEALRGADFVFSAIRVGGLQGRADDERVALAEGVLGQETV FT GAGGIAYGLRTVPVAVDIARRVARLAPDAWVINFTNPAGLVTEAMSRHLGDRAIGICDS FT PVGLGRRVARVLGADPDRAFVDYVGLNHLGWLRGLRVGGRDELPRLLADPALLGSFEEG FT RLFGAEWLRSLGAVPNEYLHYYYFNRETVRAYQEAGLTRGAFLRDQQARFYDEMRRPDA FT PALATWDRTRAEREATYMAENRETAGAGEREAEDLSGGYEKVALALMRAVARDERATLI FT LNVRNRGTLSVLDADAVIEVPCLVDANGAHPMAVDPLPDHATGLVRAVKGVERDVLAAA FT GTGSRAAAVRAFALHPLVDSVDVARRLVDGYRAVHPGLAYLR" FT CDS complement(241963..243129) FT /transl_table=11 FT /gene="SCO6671" FT /gene_synonym="SC5A7.21c" FT /product="conserved hypothetical protein SC5A7.21c" FT /note="SC5A7.21c, unknown, len: 388 aa; Similar to FT TR:Q9RSB2 (EMBL:AE002054) conserved hypothetical protein FT from Deinococcus radiodurans (338 aa) fasta scores; opt: FT 415, Z-score: 392.3, E(): 3.2e-14, 31.333% identity FT (32.639% ungapped) in 300 aa overlap. Contains nine FT degenerate PA repeats at C-terminus" FT /db_xref="GOA:O88027" FT /db_xref="InterPro:IPR011226" FT /db_xref="UniProtKB/TrEMBL:O88027" FT /protein_id="CAA19950.1" FT /translation="MASPVRVWLNRTYAENVFFMDQLRRNPADRAVEIHATHGDPDSPV FT LAAADTAELEPEGLSPAGYVEYALAQCARRGIDVFVPRLHQSAIVAHRAEFEALGTALL FT APPPEAVAVFRDKVIAYEAVRAIGVPVPPWWRVRTADELVLAVEELEAGGHRACFKPAS FT GAGGVGFRMVTRDPFSLTHLNGFPSPSVPLPLVVEALRAAEEPVDWLVMPRLEQPEVSV FT DCLTGPDNRVRLAVGRTKNGRRRGFTLHDQWLTPARRIAETFGLHHLSNVQFRMYGDRP FT VLMDVNTRPAGGLHQLALCGVNVPWAAVRLALGDDPGQLEPPFLGQDYAVVSGPRPLRP FT VTLPHQRADLPAATTPAPAPAPAAAAAPAPAPAERAAAPASSAPVGLT" FT repeat_region complement(242011..242064) FT /note="9 x 6 bp repeats" FT RBS complement(243135..243141) FT /note="possible RBS upstream of SC5A7.21c" FT RBS 243400..243403 FT /note="possible RBS upstream of SC5A7.22" FT CDS 243412..244299 FT /transl_table=11 FT /gene="SCO6672" FT /gene_synonym="SC5A7.22" FT /product="conserved hypothetical protein SC5A7.22" FT /note="SC5A7.22, unknown, len: 295 aa; similar to a FT hypothetical protein from M. tuberculosis TR:O33337 FT (EMBL:AL008967) MTV002.60C (324 aa), fasta scores; opt: FT 1202 z-score: 1507.9 E(): 0, 57.2% identity in 285 aa FT overlap" FT /db_xref="GOA:O88028" FT /db_xref="InterPro:IPR004843" FT /db_xref="UniProtKB/TrEMBL:O88028" FT /protein_id="CAA19951.1" FT /translation="MTTRAGAPGKLWAISDLHVGYEENRALVERTRPESDDDWLLVAGD FT VAETVADIRWALGILADRFRRVVWAPGNHELWTHPKDAVDLRGVARYEHLVEMCRELGV FT TTPEDPYPVWEGAGGPAVVAPLFLLYDYSFLPAGCATKAEGLEYAQGTGVVCSDEYLLH FT PDPYPSREDWCRARVAETERRLAAIPADLPTIPVNHYPLHRHPTDVLWYPEFAMWCGTS FT LTADWHRRFRVETMVYGHLHIPRTTWHEGVRFEEVSVGYPREWRKRPGPPGQLRRILPS FT TRASAAPSHQEVTR" FT RBS 244283..244289 FT /note="possible RBS upstream of SC5A7.23" FT CDS 244296..244976 FT /transl_table=11 FT /gene="SCO6673" FT /gene_synonym="SC5A7.23" FT /product="conserved hypothetical protein SC5A7.23" FT /note="SC5A7.23, unknown, len: 226 aa; similar to FT hypothetical proteins from Streptomyces and M. tuberculosis FT e.g. S. coelicolor TR:O24813 (EMBL:AB007189) (208 aa), FT fasta scores; opt: 674 z-score: 960.0 E(): 0, 49.1% FT identity in 214 aa overlap" FT /db_xref="GOA:O88029" FT /db_xref="InterPro:IPR008278" FT /db_xref="UniProtKB/TrEMBL:O88029" FT /protein_id="CAA19952.1" FT /translation="MIEELLPGTVVAVEAFGQDDAGHLPLYPEEEELVARAVAKRRREF FT TVVRSCARRAMEKLGVPAQPVLTGERGAPRWPEGIAGSMTHCDGYGAAALVRLTDLASL FT GIDAEPDGPLPDGVLESIALPAEVALLRRLGGARPGVHWDRLLFSAKESVYKAWYPLTG FT QWLDFTEADIEIRVDPADPRRGTLHAALLVPGPTVDGRRLSRFDGRWSARDGLVTTAVT FT VPRT" FT CDS complement(244995..245231) FT /transl_table=11 FT /gene="SCO6674" FT /gene_synonym="SC5A7.24c" FT /product="hypothetical protein SC5A7.24c" FT /note="SC5A7.24c, unknown, len: 78 aa" FT /db_xref="UniProtKB/TrEMBL:O88030" FT /protein_id="CAA19953.1" FT /translation="MTTAVLTDRERTAVQAYLRLLHTVRAGFDTGTGPGDSPRPPVVPP FT SVLAEAEQALRAAGLTGNEEAFFRLLRDWCPPT" FT RBS complement(245241..245244) FT /note="possible RBS upstream of SC5A7.24c" FT CDS complement(245327..245983) FT /transl_table=11 FT /gene="SCO6675" FT /gene_synonym="SC5A7.25c" FT /product="putative DNA-binding protein" FT /note="SC5A7.25c, possible DNA-binding protein, len: 218 FT aa. Contains probable helix-turn-helix motif from aa 92-113 FT (Score 1665, +4.86 SD)" FT /db_xref="GOA:O88031" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:O88031" FT /protein_id="CAA19954.1" FT /translation="MTGGFEGPGAKPTTTLAAVVARVGALADRLDVPHAEVFDVGRLSA FT ASGVPESVVGALLGGRPTGGADVQTRFVQRLDLLRRTRLKPNGRKYTQQEIADGAGMSR FT QQAGALINGDRRPTMEHCDAIQRFFRVHAGFLTAEDPEALAGALQRTEQELLQQLADRE FT RQAAAPADDPLERLLQDHGVRGIAWRAAQLPTDQHRDKVAEWLDMLLESVKRPES" FT RBS complement(245992..245996) FT /note="possible RBS upstream of SC5A7.25c" FT CDS 246168..246875 FT /transl_table=11 FT /gene="SCO6676" FT /gene_synonym="SC5A7.26" FT /product="hypothetical protein SC5A7.26" FT /note="SC5A7.26, unknown, len: 235 aa" FT /db_xref="GOA:O88032" FT /db_xref="InterPro:IPR013767" FT /db_xref="UniProtKB/TrEMBL:O88032" FT /protein_id="CAA19955.1" FT /translation="MRTPREGRIGKRGDLPMAFQAGGQRPAPRPAPATPEAQAYLQDYT FT ALLEAVPFPSLVVDHRWDVVLANGAFRTLFQGAGPHPTAMPDDNFLRFVLFHPDAATVL FT GEHESSWCLPMLAHFAATLERYGHDPGLQAVRRDIAQDPIMEAAYRQGLPHWIRAVGAR FT AVEHDGAVRPLHHPDPRRGTTECRVVVETPASLQELGYTRLTLVLREPRRAAHRAPRAR FT HTPAHLRVVPAAE" FT CDS complement(246767..247309) FT /transl_table=11 FT /gene="SCO6677" FT /gene_synonym="SC5A7.27c" FT /product="putative ABC transporter ATP-binding protein" FT /note="SC5A7.27c, probable ABC transporter ATP-binding FT protein, len: 180 aa; similar to part of many e.g. taurine FT transport atp-binding protein tauB (255 aa), fasta scores; FT opt: 309 z-score: 436.0 E(): 4.9e-17, 43.6% identity in 117 FT aa overlap. Contains Pfam match to entry PF00005 ABC_tran, FT ABC transporters, score 31.20, E-value 1.9e-09. Has large FT overlap with convergent downstream gene; database FT similarities do not extend into the overlap. The sequence FT of the cosmid has been checked, and is correct" FT /db_xref="GOA:O88033" FT /db_xref="InterPro:IPR003439" FT /db_xref="UniProtKB/TrEMBL:O88033" FT /protein_id="CAA19956.1" FT /translation="MKPQRPISARAWTRAAPRTCRHVELLLKHAALSRERCGELVAEAL FT APVGLADAAGAHPWQLSGGMQQRVAIARARAYEPEVLLMAEPFTAVDAQTRAGLGDLVR FT VLWRERGITVLFVTHDIDEAVHLGERVIVLSAAPPPALTTRHSAAGTTLRWAGVWRARG FT ARWAARRGSLRTSVNRV" FT misc_feature complement(246899..247300) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporters, score 31.20, E-value 1.9e-09" FT CDS complement(247332..248273) FT /transl_table=11 FT /gene="SCO6678" FT /gene_synonym="SC5A7.28c" FT /product="iron-sulfur oxidoreductase beta subunit" FT /note="SC5A7.28c, probable iron-sulfur oxidoreductase beta FT subunit, len: 313 aa; similar to many e.g. POBB_PSEPS FT phenoxybenzoate dioxygenase beta subunit (Pseudomonas FT pseudoalcaligenes) (319 aa), fasta scores; opt: 824 FT z-score: 993.1 E(): 0, 45.9% identity in 303 aa overlap. FT C-terminus is a 2Fe-2S ferredoxin domain similar to e.g. FT FERV_ANAVA ferredoxin, vegetative (Anabaena variabilis) (98 FT aa), fasta scores; opt: 187 z-score: 222.4 E(): 3.8e-05, FT 38.2% identity in 68 aa overlap. Contains PS00197 2Fe-2S FT ferredoxins, iron-sulfur binding region signature and Pfam FT match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster FT binding domains, score 35.50, E-value 1.2e-06" FT /db_xref="GOA:O88034" FT /db_xref="HSSP:2PIA" FT /db_xref="InterPro:IPR000951" FT /db_xref="UniProtKB/TrEMBL:O88034" FT /protein_id="CAA19957.1" FT /translation="MTRYEAELVVGRRETAADGVLVLTLRHPRDEPLPVWEPGAHVDVV FT LGPGLERQYSLCGDPGDRAVWRVAVLREKAGRGGSAYVHEELRAGDKVRVRGPRNNFRL FT ERAPRYRFVAGGIGITPVLPMLAAAEEAGAEWSLLYGGRTRAGMAFTKELERYGDRVRI FT VPEDESGLLDLASVLDDVAPGTLVYCCGPGGLLDAVEARCPAGSLRVERFRPKEAAVQA FT PAGPEFEVVLARSGRTVAVPPGTSVLDAVRETGVEVLYSCTEGTCGTCETEVVEGEPDH FT RDSVLTEEERAAGETMLICVSRCRGRRLVLDL" FT misc_feature complement(247341..247595) FT /note="Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur FT cluster binding domains, score 35.50, E-value 1.2e-06" FT misc_feature complement(247464..247490) FT /note="PS00197 2Fe-2S ferredoxins, iron-sulfur binding FT region signature" FT CDS complement(248270..248440) FT /transl_table=11 FT /gene="SCO6679" FT /gene_synonym="SC5A7.29c" FT /product="hypothetical protein SC5A7.29c" FT /note="SC5A7.29c, unknown, len: 56 aa" FT /db_xref="UniProtKB/TrEMBL:O88035" FT /protein_id="CAA19958.1" FT /translation="MSGRTGEIYRIAWLPGTDVLHGTCHCGAEHTAEDPVAMWDWMLAH FT PRGHDLPGDGS" FT CDS complement(248437..249516) FT /transl_table=11 FT /gene="SCO6680" FT /gene_synonym="SC5A7.30c" FT /product="oxidoreductase alpha subunit" FT /note="SC5A7.30c, probable oxidoreductase alpha subunit, FT len: 359 aa; similar to many e.g. VANA_PSES9 vanillate FT demethylase (monooxygenase) (329 aa), fasta scores; opt: FT 636 z-score: 695.7 E(): 1.7e-31, 34.6% identity in 338 aa FT overlap" FT /db_xref="GOA:O88036" FT /db_xref="InterPro:IPR017941" FT /db_xref="UniProtKB/TrEMBL:O88036" FT /protein_id="CAA19959.1" FT /translation="MPHMTAFARNQWYVAAYSHEVGRELLGRTVLGEPLVLYRAEEDGG FT PVVLHDRCVHRRYPLSEAPTRLDGDRIVCGYHGFTYDTTGTCVYVPGQKRVPRTARVAS FT YPVAERDSLVWVWIGDPALADPEAVPRARHLDAPGWVTVRGMEPIDADYGLLVDNLLDL FT SHETYLHGGHIGTPEVAETPITTEVDEGAGIVRVSRHMDDAECPPFYARSTGIVGRIDR FT WQDIEYHAPCLYVLHSRVAPTGTVPAPDGGDPEGFHTEITYAITPSGDGKVYDFWAVSR FT DWATDDAEVTEFLYKSNRTVVMQDVDALNLLQRTLGGERAGYQELSINIDTGGLAARRI FT LARLVEEGEGAGTGPRVAR" FT RBS complement(248445..248449) FT /note="possible RBS upstream of SC5A7.29c" FT RBS complement(249523..249526) FT /note="possible RBS upstream of SC5A7.30c" FT RBS 249658..249661 FT /note="possible RBS upstream of SC5A7.31" FT CDS 249664..252456 FT /transl_table=11 FT /gene="SCO6681" FT /gene_synonym="SC5A7.31" FT /product="putative serine/threonine protein kinase" FT /note="SC5A7.31, unknown, len 930 aa; some similarity to FT several e.g. PKN2_MYXXA serine-threonine-protein kinase FT Pkn2 (Myxococcus xanthus) (830 aa), Smith-Waterman scores; FT E: 1.5e-06, 23% identity in 829 bp overlap. Also has short FT segment of similarity to the active site regions of several FT Serine-Threonine protein kinases e.g. PKAA_STRCO P54739 FT serine-threonine protein kinase pkaA (533 aa), blastp FT scores; Expect= 3.7e-05, 39% identity in 27 aa overlap. FT Contains possible transmembrane anchor and six degenerate FT repeats of the sequence VDETTR" FT /db_xref="GOA:O88037" FT /db_xref="InterPro:IPR007822" FT /db_xref="UniProtKB/TrEMBL:O88037" FT /protein_id="CAA19960.1" FT /translation="MTAATVRGGTPRDSVVSVSNRWEGAGVNKGYAVYCDADPYFYDAP FT HRTADRTGAARSRYAAASSPVPEGWQRHESGDWLALRPADADLPAQGWKIHVSACLDNA FT ESVLDRVWRHCVDGGTAFKFVPSRYLLHQRNAKYADRAGSGKFVTVYPADEAEFERLVG FT ELSELLAGEPGPHILSDLRIGDGPVHVRYGGFTRRDCYDADGELRPAVSGPDGVLVPDL FT RGPVFRIPEWVDPPAFLRPHLDARSAVTVTGMPYTVESALHFSNGGGVYLARDTRTGAR FT VVLKEARPHAGLAADGADAVTRLHRERRALERLSGLACTPEVLDHRTVGEHHFLVLEHI FT DGKPLNTFFARRHPLIEADPGERRLAEYTDWALDVHARVERAVAEVHARGVVFNDLHLF FT NIMVRDDDSVALLDFEAAHHVDEAGRQIVANPGFVAPPDRRGVAVDRYALACLRIVLFL FT PLTSLLAVDRHKAAHLAEVVAEQFPVDRAFLDAAVEEITRVDGSTRVDGSTRADETTRA FT DETTRLDVTTRVHGAPDAARRPAGPVAPVRPDDWPRSRDSMAAAIRASATPSRTDRLFP FT GDIAQFATAGGGLAFAHGAAGVLYALAESGAGRDEDGEQWLLERTKRPPSGMPLGFHDG FT LAGLAWTLERLGHRDRALDLAELLLDQPLDHLGPDLHGGTAGLGLALESLAATTGQAAL FT HSAALHCAELAADGLPGGSVPADRVSRGRARAGLLYGGAGRALLFLRLFERTRDSALLD FT LARDALRQDLARCVRGAGGALQVDEGWRTMPYLGAGSVGIGMVLDDYLAHRADEEFARA FT ANEIVAAAQAMFYAQPGLYRGVAGMVLHLGRTTATAPGTGPRAVRRQLDALSWHAMSYR FT DRLAFPGEQMMRLSMDLSTGTAGCLLAVASVLGDAPAGLPFLPPPRRSGGPLTRPHQEP FT " FT repeat_region 251140..251247 FT /note="6x 18 bp repeats" FT misc_feature 251543..256522 FT /note="99.98% identical (1 conflict) to SC03771 U03771 FT Streptomyces coelicolor A3(2) aerial mycelium formation FT gene cluster (ramA, ramB, and ramR) genes from 1 to 4980" FT RBS 252482..252486 FT /note="possible RBS upstream of SC5A7.32" FT CDS 252494..252622 FT /transl_table=11 FT /gene="SCO6682" FT /gene_synonym="SC5A7.32" FT /product="hypothetical protein SC5A7.32" FT /note="SC5A7.32, unknown, len: 42 aa; similar to CDS FT upstream of S. griseus RamA TR:Q07642 (EMBL:D13614) (43 FT aa), fasta scores; opt: 154 z-score: 293.0 E(): 4.4e-09, FT 53.7% identity in 41 aa overlap" FT /db_xref="UniProtKB/Swiss-Prot:O88038" FT /protein_id="CAA19961.1" FT /translation="MNLFDLQSMETPKEEAMGDVETGSRASLLLCGDSSLSITTCN" FT CDS 252658..254568 FT /transl_table=11 FT /gene="SCO6683" FT /gene_synonym="ramA" FT /product="putative ABC transporter" FT /note="SC5A7.33, ramA, probable ABC transporter, len: 636 FT aa; N-terminus contains transmembrane domain, C-terminus FT contains ATP-binding domain. Almost identical to TR:Q53818 FT (EMBL:U03771) potential ATP-binding membrane transport FT protein RamA (636 aa)(99.8% identity in 636 aa FT overlap)Y08A_MYCTU hypothetical ABC transporter ATP-binding FT protein MTCY50.10 (631 aa), fasta scores; opt: 556 z-score: FT 414.6 E(): 7.4e-16, 28.1% identity in 626 aa overlap. FT Contains sixteen degenerate GA repeats at C-terminus, FT PS00017 ATP /GTP-binding match to entry PF00005 ABC_tran, FT ABC transporters, score 139.50, E-value 6e-38. Some FT similarity to RamB (E(): 3.7e-05, 32.7% identity in 627 aa FT overlap)" FT /db_xref="GOA:O88039" FT /db_xref="HSSP:1JJ7" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:O88039" FT /protein_id="CAA19962.1" FT /translation="MSPAAGAPGSGPGRRRLPALDVRRFSPVRKSRPVPPRAPGRALEV FT LVLLCSVAAAVAAVAQPLALGRTLDLLLRDGDAGWWLPLSAALLLGELLLDSATSLFTG FT RCNATWTASVRTRALRGLLRTAPEHARPYPPGDIGTRLTLNAADAGGAPAARAALAASL FT ITPLGALVALALVDVWVALCVLTGLPALALLLRSFARDTGATVAAYQRTQSLIASRLLE FT ALEGADTIGAAGTGERERARVLAPLAELAAQGRHMWALHGRALGRSGVLVPLLTLAATA FT VGGLRLAAGELSVGDLLAVGRYAQLTAGVGAAASLLGAIVRAREARRRTRELERMTATV FT YGTRRLPPNGPGELRLCGVRVLRGGREVLRADGVRVPGGSTVAVVGRSGAGKSVLAAVA FT GRLIDPDEGYVLLDGVRLDRLTHEALRTEVAYAFERPVLGEGTIAEAVADGARRSSRER FT VRQAARAAGADGFVRRLPHGYDTPLPRAPLSGGEHQRLGLARAFAHAGRLLVLDDATSS FT LDTATEHEVDLALRRSVRPGTRLVVAHRPSVADRADLVLWLEDGQVRAVGTHRELWHTA FT GYREVFGAGAGAGAGAGAGAGADAGAGADAGPGPDSGAATAVGGSGPGPVRRPEPEEAR FT P" FT misc_feature 253792..254340 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporters, score 139.50, E-value 6e-38" FT misc_feature 253813..253836 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT repeat_region 254404..254499 FT /note="16 x 6 bp degenerate repeats" FT RBS 254554..254557 FT /note="possible RBS upstream of ramB" FT CDS 254565..256391 FT /transl_table=11 FT /gene="SCO6684" FT /gene_synonym="ramB" FT /product="putative ABC transporter" FT /note="SC5A7.34, ramB, probable ABC transporter, len: 608 FT aa; N-terminus contains transmembrane domain, C-terminus FT contains ATP-binding domain. IdenticalTR:Q53819 FT (EMBL:U03771) potential ATP-binding membrane protein RamB FT (608 aa) and similar tyo many e.g. Y07D_MYCTU hypothetical FT ABC transporter ATP-binding protein MTCY02B10.13 (579 aa), FT fasta scores; opt: 456 z-score: 443.0 E(): 1.9e-17, 31.8% FT identity in 614 aa overlap. Contains sixteen degenerate PE FT repeats between the N- andC-terminal domains. Also contains FT PS00017 ATP /GTP-binding site motif A (P-loop), PS00211 ABC FT transporters family signature and Pfam match to entry FT PF00005 ABC_tran, ABC transporters, score 157.10, E-value FT 3e-43. Some similarity to RamA (E(): 2.7e-05, 33.4% FT identity in 628 aa overlap)" FT /db_xref="GOA:Q53819" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q53819" FT /protein_id="CAA19963.1" FT /translation="MTSTEAGALRRLAPPARRFLAHRKGVLVRLALWSLAESGQAFLVG FT HAVARSVDEGFLAGDPRRGLLWLGVALVAVLSGARVVRGVFAQLAGVTEPLRDGLVRHA FT VDRSMARAAPGGPGGTDRAAVSRLTNQVEIARDSFAGLVLTLRSFVFTAAGALLGLLSL FT HPALLVVVLPPLAAGLALFLVTLRPMAAAQRRALAADEALGEHAASARAALRDLTACGT FT GPGAERHGADLVADAAAAARTLAGWAAVRTAALGVAGHLPVLALLVAVEWLRGHGVSVG FT ALLGAFTYLVQSLLPALHTLMTALGAAGSRLLVVLDRILGPEPEPEPEPEPEPEPELGS FT GLEPEPEPASEPESGPSTASASAAAFAVHTAAAPAVELRSVTLSYGVRAEPVLDALDLR FT VAPGEHLAVVGPSGIGKSTLTRLVAGTLAPSRGEVRVAGRVVTGRPAAELAALRVLVPQ FT DAYVFSGTVGDNLAYLRTDPSPAELDAAVEAFGLAPLVERLGGLDATVRPAELSPGERQ FT LVALVRAYLSPAPLLLLDEATCHLDPASEARAEKALAGRSGTLVVVAHRLSSAVRADRT FT LVLDGIRAQSGTHAELLGRSPLYRDLTGHWNS" FT repeat_region 255528..255623 FT /note="16 x 6 bp degenerate repeats" FT misc_feature 255771..256307 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporters, score 157.10, E-value 3e-43" FT misc_feature 255792..255815 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT misc_feature 256095..256139 FT /note="PS00211 ABC transporters family signature" FT CDS complement(256396..257004) FT /transl_table=11 FT /gene="SCO6685" FT /gene_synonym="ramR" FT /gene_synonym="SC6G3.01c" FT /product="putative two-component system response regulator" FT /note="SC5A7.35c, ramR, two-component system response FT regulator, len: >41 aa. Identical to TR:Q53820 FT (EMBL:U03771) potential response regulator for aerial FT mycelium production RamR (202 aa), and similar to many e.g. FT Streptomyces peucetius TR:Q54821 (EMBL:L37338) daunorubicin FT biosynthesis regulatory protein dnrN (202 aa), fasta FT scores; opt: 173 z-score: 382.4 E(): 4.6e-14, 65.0% FT identity in 40 aa overlap" FT /note="SC6G3.01c, ramR, probable two-component system FT response regulator, partial CDS, len: >201 aa; previously FT sequenced as TR:Q53820 (EMBL:U03771), RamR, potential FT response regulator for aerial mycelium production. Similar FT to many two-component system transcriptional regulators FT e.g. TR:Q07640 (EMBL:AB006206), AfmR, Streptomyces griseus FT transcriptional regulator involved in aerial mycelium FT formation (210 aa), fasta scores; opt: 466 z-score: 545.2 FT E(): 4.9e-23, 42.6% identity in 202 aa overlap. An FT alternative start codon is present at codon 4. Contains FT probable helix-turn-helix motif at aa 158-179 (Score 1876, FT +5.58 SD). Contains Pfam match to PF00196 GerE, Bacterial FT regulatory proteins, luxR family" FT /db_xref="GOA:Q53820" FT /db_xref="HSSP:1FSE" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q53820" FT /protein_id="CAD55386.1" FT /translation="MGEMVRIAVVHDEKLLRSALVQLLRSDDTLDVSSHCLDADGPELS FT AALPADVCVVDGECLTGPEDAGAGRLRARYGDRLVVLATAKRPGVLRRAFDGGALGLVD FT KNAPAHRLITAVHTVARGERFLDETLTVALLKGAEMPLTTRELGVLTLASQGAPIAEIA FT ARLHLSRGTVRNYMATAVRKVGARNRVDAIRIVQSAGWT" FT misc_feature 256400..256522 FT /note="overlap with Streptomyces coelicolor cosmid 5A7 FT (EMBL:AL031107) from 40215 to 40337." FT misc_feature 256400..258171 FT /note="sequence equivalent to EMBL:U03771 from 4858 to FT 6629" FT misc_feature complement(256402..256590) FT /note="Match to PF00196 GerE, Bacterial regulatory FT proteins, luxR family Score 52.54" FT CDS 257533..258411 FT /transl_table=11 FT /gene="SCO6686" FT /gene_synonym="SC6G3.02" FT /product="conserved hypothetical protein" FT /note="SC6G3.02, hypothetical protein, len: 292 aa; unknown FT function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Similar to TR:Q9RJY9 (EMBL:AL133210) Streptomyces FT coelicolor hypothetical protein SCF37.12, 284 aa; fasta FT scores: opt: 864 Z-score: 995.3 E(): 8.3e-48; 47.902% FT identity in 286 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9XAH8" FT /protein_id="CAB46974.1" FT /translation="MGWLAAGDTYEVALVEGRVVARSASAKSPAEGRRERTLPAEIRER FT PEVVELQRFAEWLDRHAAECVAQVDNWMVSSLPVPTALLAQVWPDEAWQTALRDIVVVG FT EGPDEVGFLRDADESQGLRVVNLDGETVRLTSRTVTMPHPVLLPDLEELRTFAAESGVV FT QGVEQIHRATWPAPGDSDGGDTDVVTEFAGAEYRSWFHLSARATSLGYRISGSRVVDRI FT RDAGRVFTASVGMSDPYTEEKAWTGGLSWSHGDGYRSLPLHEVGPVAYSEGMRMAAALH FT AGRTVPTDGAE" FT CDS 258452..263488 FT /transl_table=11 FT /gene="SCO6687" FT /gene_synonym="SC6G3.03" FT /product="putative DNA-binding protein" FT /note="SC6G3.03, hypothetical protein, len: 1678 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Contains probable helix-turn-helix motif at aa 1209-1230 FT (Score 1004, +2.61 SD). Similar to TR:Q9RJY8 FT (EMBL:AL133210) Streptomyces coelicolor hypothetical FT protein SCF37.13, 1726 aa; fasta scores: opt: 690 Z-score: FT 706.5 E(): 1e-31; 35.556% identity in 1800 aa overlap" FT /db_xref="GOA:Q9XAH7" FT /db_xref="UniProtKB/TrEMBL:Q9XAH7" FT /protein_id="CAB46975.1" FT /translation="MSDGTTRHGAAEEVAELLRSGAVLPPGTTGGGDRAVPVFTRAYRH FT PGLDDRIVVRLTPADPSGTEPAAGDPAGGDGGGFLGLLPVGEPVEVGVGQHRAMGFPEW FT VLVRHPTDGHLAMSLVEEMNKVARTVRSRAKRARATYESIGARLAGSVPHFLPTFYEEA FT GRVFLAAGEKAYASQMFVNARKAETAHALPFDEARMDAVFLEFALADAMPTKVLSSYAK FT GLSSRVPAATAYRHLRGLFVRLAAHGVAPSSPGAGDLRKLAKAVAGRNALAEEMAYLRE FT VLPLPGTRKAPPGWWKAHRAALLELSRREPAARGTLLGLLPSEWEHEELGQWLDLLDKT FT GATEGLCDATLPAEARSPDGTAGWTRRFLALCRTHERYLAPSELYPLVDRMAGALRAEL FT NDENATLRPPVGDVDLLDQLLALDVPVGDPEARPWLNLQDWAARDGRRDLLALAADTRF FT REVFRSGCPTYEREGIDKRTVARLAESPGGRPMLAEWVAGVSRGYLICGLGDFTLNSGP FT FQTLNWLPGEILATAEQEVRDALGTGMAPVLGRALRNGLLDELGWPAWDEAIGSSASPE FT QARATQVAEAWPHLVVLQGTHARVLGAQGTVLSHQLRLPDERGPGSPDVRYVDGALLVS FT WYVSATSTSYGYWYHPDTGVSPTTELTGDVRSCYACHADGSGGTNGMPPASLPLPGGGR FT TTGHGVLRPGDTHVPWRRRVIGDGTSHWVWIDDWSREKNSTWHAYEPADDTAGERGGPD FT WFAEGLRAAPEGSTLGACWLLPAPSAEPGPVCAPVDGLLGWRVIIGPDGSRHGQDLAGH FT SVVVPRRVGGSPENALVFPGTDRAVTVMRWSSDLQLRDSDQAVLAHFKRDQTAGPFSAG FT TPLLPPLRYWHLLRPRDPQGSAALRRVGDDVAAELLAAAVAETTGDGAADRDAVLGPVR FT TLFPEVGDEALLRGITGVARYAAEQQRVLDGLLARLDSAVRGVVPEEQRPALGDRLLAS FT ALNGVGLTERDARWYYDFQHSLFELPQLLARSMKGLAEPAPAGIFHLSLAKQEPLEHLN FT GLALPELPAVLALRAASEATEEEHRQALDTFLGELDAHGLTELDPGHWRRVHLAFDPDT FT FDGPGDTHGYRRGTVLNLEGGAFLVFPDDWYQFVREYGPHEVKGKHYGAAYHDPSGRFE FT TPAPYTPVSEEPFVPEPTRAPGWVAAFRAELAERGPVPWRPEAAEEFARLTGVTPTTAR FT LVLAGMPQTDDKRANVPSATLKVIGVKSADARVSKDELRSLDSAALRAVVAALLPTEPS FT RLWTHGPDTARAAEVWNERLGRRTPLPEDVLHDAVRTVEPVGWAPADALRGFVNLATEP FT RLTTDLTWSFGRYYLETAEQTPRFDSSVLKGSVALAAWLAHRLPSGDPLRATLPGVLTA FT LRERLAHPGLLLALDRRGIDWEAFRRAASDPAETGDDFERHGAVVLGTERTEPLPAIRP FT ALLDAAGHDPHLAALYTGERPNAQETALRLVHDRPFAELLADPGDPLAGERDADGLWWP FT QDPARSVPDLVGEAAKRYGIGEDAAVLYLMLLAMPDPTDRNTARWTGWGGQRGGTARLR FT AARAELAATDLVVEGSRSKAGRSLFLPGGWTRPGNPHLPLERWKLPMYDLLEGEAPVLG FT VVVPTRPVPAVYREAWQRVQDGDAPRLEELEVPRPGRRRR" FT CDS 263569..267084 FT /transl_table=11 FT /gene="SCO6688" FT /gene_synonym="SC6G3.04" FT /product="conserved hypothetical protein" FT /note="SC6G3.04, hypothetical protein, len: 1171 aa; FT unknown function, C-terminal 380 aa (approx.) similar to FT SW:YEHP_ECOLI (EMBL:AE000301), yehP, Escherichia coli FT hypothetical protein (378 aa), fasta scores; opt: 610 FT z-score: 603.7 E(): 2.7e-26, 34.5% identity in 394 aa FT overlap and N-terminal 750 aa (approx.) similar to FT SW:YEHM_ECOLI (EMBL:AE000301), yehM, Escherichia coli FT hypothetical protein (759 aa) (25.4% identity in 796 aa FT overlap). The hypothetical proteins yehMP are adjacent on FT the E.coli chromosome. Part of this probable CDS (aa FT 530-830 approx.) is also similar to TR:Q54218 (EMBL:X77865) FT Streptomyces griseus putative chain length determination FT factor (412 aa) (31.5% identity in 340 aa overlap)" FT /db_xref="InterPro:IPR002035" FT /db_xref="UniProtKB/TrEMBL:Q9XAH6" FT /protein_id="CAB46976.1" FT /translation="MTARKETATEVVVPTARTRPYLIGIRHHSPALAVAVPRLLDAADA FT EVVCVELPSDFQPWLPYLADPRTVAPVALSGAHADGRLGLYPLADFSPELAAIRWARER FT GAEVVCCDLPLADPAWLCGPPDGITADADELWDRTVEALAPGSAPEAVRRAALAFGRAL FT RDDSAAHAGIGAGDLAREAHMRRILAARGQRRVAAVIGAFHVPGLSDEDAPGTVAETAP FT DAGPSSPVVTSLVPYAFAQLDPGSGYPAGIRAPRWRQAVLDAGGDPGRVRAAAARFLTE FT VCREIRASGDTAGTGEAVEALRLAGDLGTLRGLPVPGRRELVEAVTSVLGRGQALDREL FT GAVLVGTGRGRLAPGTPRSGLGPWVEAELAALRLPGPADPGGRDLRLTPLRSTLDARRE FT ILLQRLKECGVGYAEPVEVTGAGEGSALTTRWRAAWTPSVAARLDLVGVRGVTAAQAAD FT GTLRENHRRAAEAGRVTSARVVALLGAAARCALTDLLHDGLTEAERVLPGAAALPELLA FT ALDLLDSVRRRHLPGTTETVRIRAARLAGLLLDAAVRLLPGLAGSDEPRDAVAVVTLAV FT RSAADRLGLRLDGELYALSRRGSPLLQGAAQAARVLLDLDGSDLLGTRLAGWVDTATGP FT DGRRRLERRLTGVLVAAGFLIESASTALGPLFERVETMSDRGFLDRLYALRGGFRALTP FT QGRSRVLAAVSDRLGDRPDLRLPAPAELVGRWAAADGEGLALLGELGLADLASAPAAKD FT AGATSAPAPRTAPSGAEVPHGAGAPRLGPADRWRLLLGRDTAGLPAALRPYARALDELF FT DREGEEADEESRETNEGGDGGEPEPGAGGTSEGSDDDRTGGAARSFPSVRHWAEDLRTL FT FGAEIRQEVLERAVADGRTDVIALLDPASVRPSVELLSAVLTLARGMPEQRVASLRPLV FT KRLVEELTKELATRLRPTLTGLTTPRPTRRPGGPLDLPRTLRANLAHIRRREDGRVEVV FT PERPVFRTRTARRNDWRLILVVDVSASMETSVVWSALTAAILGGAPTLSTHFLTFSTQV FT ADLTGLVADPLSLLLEVKVGGGTHIAAGLAHARSLVTVPDRTLVVVVSDFEEGAAVEGL FT LAEVGALVSAGVRLLGCAAPADGGTPRYSVPVTRRLVAAGMPVAALGPLSLARWVGAQV FT RGAAR" FT repeat_region 266445..266485 FT /note="imperfect 41 bp inverted repeat" FT CDS 267081..268847 FT /transl_table=11 FT /gene="SCO6689" FT /gene_synonym="SC6G3.05" FT /product="conserved hypothetical protein" FT /note="SC6G3.05, hypothetical protein, len: 588 aa; similar FT to TR:Q9RJY5 (EMBL:AL133210) Streptomyces coelicolor FT hypothetical protein SCF37.16, 667 aa; fasta scores: opt: FT 633 Z-score: 604.5 E(): 4.9e-26; 40.441% identity in 680 FT aa overlap. Probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition" FT /db_xref="GOA:Q9XAH5" FT /db_xref="InterPro:IPR007527" FT /db_xref="UniProtKB/TrEMBL:Q9XAH5" FT /protein_id="CAB46977.1" FT /translation="MTRSRPGTAPSLPPVAPEVFAAAVEGLSTRLRRRLDAAVESLAAT FT SADAAEDGTYGIRCGEDALVTLAPGPSGTITSPDQAHCTCLLSPRCLHRAAALGAAPVA FT DPAPPAGTALPTAPVALPARGPSAGQVRAAEGLWTAAAAVLAAGITAAGAVARAELLRA FT AHTARLAGLHRAEGAALDVVRHLRDARDPQGAHRVQRPAGPVAALRELLLVTHRLKAAD FT PDPGLIGAAHHHRPDGPLRLHGVCREPVTGPGALGGVLTHLVDDAGRWYTLRDVAPGGP FT ERARRAGTAHVALRSFLSDHERLSRGGLVVTGAVVAPDGRLLAEPGVRATFAAGRPWAG FT FAPAAAADRTGDAPPLTGCDVEIVAADGEGVLARIDTGDGPGPAVRLAPAHRHPALAHT FT ANLRRLGACPGLRVRVLGRVDPDRVTTLRPLAVGPVPGAGAATLRLPDEWRDRADLGYD FT RLCDAHFTAAAPGPAPSPPPLAAADASPVDSPLRRVRDLVELAVTGGRRAAAEPARDGD FT RGAHAAVLRRGGFATGADLYAALGAVAARRPRDAFGRPAGDDLDRYAAQWLATAVYLNG FT TEAALRRGLWHR" FT repeat_region 267653..267693 FT /note="imperfect 41 bp inverted repeat" FT repeat_region 268848..268879 FT /note="imperfect 32 bp direct repeat" FT repeat_region 268885..268916 FT /note="imperfect 32 bp direct repeat" FT CDS complement(268926..270206) FT /transl_table=11 FT /gene="SCO6690" FT /gene_synonym="SC6G3.06c" FT /product="putative transmembrane transport protein" FT /note="SC6G3.06c, probable transmembrane transport protein, FT len: 426 aa; similar to many transporters e.g. FT SW:KGTP_ECOLI (EMBL:X53027), kgtP, Escherichia coli FT alpha-ketoglutarate permease (432 aa), fasta scores; opt: FT 1088 z-score: 1249.1 E(): 0, 41.1% identity in 419 aa FT overlap. Highly similar to TR:Q03095 (EMBL:M64783) FT Streptomyces hygroscopicus putative bialaphos transport FT protein (447 aa) (57.3% identity in 412 aa overlap). FT Similar to TR:O86563 (EMBL:AL031184) S.coelicolor probable FT transmembrane transport protein (472 aa) (31.7% identity in FT 436 aa overlap). Contains hydrophobic, possible FT membrane-spanning regions. Contains Pfam match to PF00083 FT sugar_tr, Sugar (and other) transporter, PS00216 Sugar FT transport proteins signature 1 and PS00217 Sugar transport FT proteins signature 2" FT /db_xref="GOA:Q9XAH4" FT /db_xref="InterPro:IPR005828" FT /db_xref="UniProtKB/TrEMBL:Q9XAH4" FT /protein_id="CAB46978.1" FT /translation="MDTEAPAPPTRRPVRQLLAASVGNAVEWYDWYAYTFLATYIADQV FT FPKGADNSLVPLLSTFAVFAVGFFMRPVGGLLMGAIADRRGRRAALTVTILLMGGSSLL FT VGLTPTYAAAGVLAPVVLVLARLLQGLSVGGEFAASTTFLVESAGPGRRGLFSSFQYVS FT TTAGQLVASGIATLLVDTLSEDRMNGWGWRLPFVFGAVLSLVGFWIRQGAQETRSTEQQ FT RAPRPALFEALRRHPRESLLICGITAGGTIAYYTWTSYLPTYAELNAGVAKSDALLAGT FT ISLAFFGLLQPLGGLLSDRFGRRPLLLFFGVGFALLSVPLLHSLRDSFAVLLLVQCAGM FT VLLTGFTSISAAVNAEVFPPRVRAAGIGFPYSLTVALFGGTAPYVGTLFKDLGHSGIFP FT WYVAVLCLLSSLVYLRLPETAHKELRR" FT misc_feature complement(268932..270161) FT /note="Match to PF00083 sugar_tr, Sugar (and other) FT transporter Score 183.52" FT misc_feature complement(269274..269327) FT /note="PS00216 Sugar transport proteins signature 1" FT misc_feature complement(269748..269825) FT /note="PS00217 Sugar transport proteins signature 2" FT CDS 270399..272462 FT /transl_table=11 FT /gene="SCO6691" FT /gene_synonym="SC4C6.01" FT /gene_synonym="SC6G3.07" FT /product="putative phospholipase C" FT /note="SC4C6.01, probable phospholipase C, partial CDS, FT len: >501 aa; similar to e.g. SW:PHLN_PSEAE (EMBL:M59304), FT plcN, Pseudomonas aeruginosa non-hemolytic phospholipase C FT precursor (692 aa), fasta scores; opt: 1073 z-score: 1149.1 FT E(): 0, 44.7% identity in 524 aa overlap" FT /note="SC6G3.07, probable phospholipase C, partial CDS, FT len: >221 aa; similar to e.g. SW:PHLN_PSEAE (EMBL:M59304), FT plcN, Pseudomonas aeruginosa non-hemolytic phospholipase C FT precursor (692 aa), fasta scores; opt: 853 z-score: 1021.1 FT E(): 0, 51.3% identity in 232 aa overlap. Continues in FT cosmid 4C6 (EMBL:AL079355) as SC4C6.01" FT /db_xref="GOA:Q8CJM0" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q8CJM0" FT /protein_id="CAD55387.1" FT /translation="MAEVNRRRFLQLAGATTAFSALSASIDRAAALPANHRSGSIEDVE FT HIVVLMQENRSFDHYFGTLRGVRGFGDPHPVRLDDGRSVWHQRKGDGTEVLPFHPEADD FT LGMQFLEGLPHGWSDGQDAYHDAKYDRWLPAKGTTTMAYLTREDIPFHYALADTFTVCD FT AYHCSFIGSTDPNRYYLWSGHTGNDGAGGGPVLGNDELGYDWTTYPERLEAAGVSWKIY FT QDVGDGLDAAGHWGWIDDAYRGNYGDNSLLYFNKYRNAKPGDPLYDKARTGTDAKRGEG FT YFDRLRADVKAGKLPEISWIAAPEAFSEHSNWPSNYGAWYISQVLDALTSNPKVWAKTA FT LFITYDENDGFFDHVVPPLPPKSAAQGRSTVDVSLDVFEGSAKHREGFYGLGPRVPMLV FT VSPWSKGGFVCSETFDHTSVIRFMERRFGVHEPNISPWRRAVCGDLTSAFDFSRTDSRP FT ARLPDTDAYEPPDRERHPDYRPTPPADPGMPRQERGTRPTRPLRYAPHVDGAVDTAAGK FT FTLAFASGPRAGAAFLVTSGNRTDGPWTYTTEAGKDIADTWNSAYSGGSYDLTVHGPAG FT FLRVFRGANEVAGPAGPEVTARHRGDDLRLTLTHTGTGTVRLRIANAHDGRTRSVTVRP FT GATVHHTVGLARSRRWYDVTVTSETAPAFLRRFAGHVENGRPGTSDPAIVTD" FT misc_feature 270957..271061 FT /note="overlap with Streptomyces coelicolor cosmid 4C6 FT (EMBL:AL079355) from 1 to 105" FT repeat_region 272231..272256 FT /note="repeat 1; 26 bp imperfect inverted repeat" FT CDS complement(272516..273469) FT /transl_table=11 FT /gene="SCO6692" FT /gene_synonym="SC4C6.02c" FT /product="putative integral membrane protein" FT /note="SC4C6.02c, probable integral membrane protein, len: FT 317 aa; similar to TR:O86668 (EMBL:AL031182) S.coelicolor FT probable integral membrane protein (299 aa), fasta scores; FT opt: 288 z-score: 279.1 E(): 3.2e-08, 32.8% identity in 299 FT aa overlap and to TR:O33234 (EMBL:Z98209) Mycobacterium FT tuberculosis hypothetical protein (301 aa) (28.8% identity FT in 299 aa overlap). Contains hydrophobic, possible FT membrane-spanning regions. Weakly similar to TR:O86668 FT (EMBL:AL031182) S.coelicolor putative integral membrane FT protein (299 aa) (32.8% identity in 299 aa overlap)" FT /db_xref="UniProtKB/TrEMBL:Q9XAN8" FT /protein_id="CAB45566.1" FT /translation="MNAALVAVLLSLVSACAYAAAAVAQERLASRASGAGALRMLASGA FT WWWAVALNSSAALLHVVALKYGPLTVVQPLGALTLVAAVPLGARLAGRRVSAIEWRGTG FT LTLLGLGALLLTASGPAPDDVLSVPEALTVSGATAALIGVLSRPGARPGLRHATASGIA FT SGVASALTQTVTVAVTDRSGPLLSVQVIGVAVLVAAFATGGLLLSQTAYRGGLGAPLAV FT VTLANPVAAAVIGLSLLGERLRGGAGGVLLALTGAALAAWGVLQLSRAAPDRPETAAPG FT LAGPGLAGTETEPTGPAPAGPGVVPRQPGPGHLTRL" FT repeat_region complement(272561..272586) FT /note="repeat 1; 26 bp imperfect inverted repeat" FT CDS complement(273466..274281) FT /transl_table=11 FT /gene="SCO6693" FT /gene_synonym="SC4C6.03c" FT /product="putative membrane protein" FT /note="SC4C6.03c, possible membrane protein, len: 271 aa; FT similar to TR:Q9KZ06 (EMBL:AL355752) Streptomyces FT coelicolor putative integral membrane protein SC10B7.28, FT 287 aa; fasta scores: opt: 489 Z-score: 561.8 E(): 1.2e-23; FT 36.471% identity in 255 aa overlap. Unknown function, FT probable CDS suggested by positional base preference, GC FT frame plot and amino acid composition. Contains FT hydrophobic, possible membrane-spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9XAN7" FT /protein_id="CAB45567.1" FT /translation="MNARSEPAQAGPDTPARPPLVRELLLVAGLFLVYKFGRRLATGET FT AEAFRNAHHVWDWERVLRLPDEGAVQSLLLHGDTLIHVANTYYAAVHFPATVAFLVWLY FT LRRPAHYLWARRVLAAVTGAALVLHLLFPLAPPRMLAATGLIDTARLFGPSVYGPPRTD FT TLSNQFAAMPSLHFGWALMLAIGLIVATRTRWRWLWLLHPLVTLLVIVGTANHYWLDVI FT VATALLGLALAVLRLPERPGRPRCALPHRRTEVRRRSSAERPELVGAGR" FT stem_loop 274366..274415 FT /note="stem is 21/22 (95%) matches, 0 gaps; loop is 6 bp" FT CDS 274457..275071 FT /transl_table=11 FT /gene="SCO6694" FT /gene_synonym="SC4C6.04" FT /product="putative transcriptional regulator" FT /note="SC4C6.04, possible transcriptional regulator, len: FT 204 aa; similar to many e.g. TR:P72185 (EMBL:U51164), HemR, FT Propionibacterium freudenreichii repressor protein from FT hemYHBXRL gene cluster (involved in the biosynthetic FT pathway from glutamate to protoheme) (259 aa), fasta FT scores; opt: 205 z-score: 251.7 E(): 1.1e-06, 28.5% FT identity in 200 aa overlap. Contains probable FT helix-turn-helix motif at aa 45-66 (Score 1187, +3.23 SD). FT Weakly similar to others from S.coelicolor e.g. TR:O69987 FT (EMBL:AL022268) S.coelicolor probable transcriptional FT regulator, partial CDS (>111 aa) (42.4% identity in 85 aa FT overlap) is similar to the N-terminal half" FT /db_xref="GOA:Q9XAN6" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9XAN6" FT /protein_id="CAB45568.1" FT /translation="MTSQDADRPEAAGTSRRSKITPEREQEFFDAVLDQLRSCGYDAVT FT MEGIAASTRCSKSTLYRQWKTKPQFVAAALRSNRRVRFTDIDTGSLAEDLRQVAAAAGE FT GAGKDTGLLQALGHAVMEDPELKCALREALVEPEIAALRAILARGVARGEVPAGHPALE FT YVPAQLFGMLRMRPVLEGEQADAAYLVRFVEAVVLPALGLP" FT CDS complement(275240..276283) FT /transl_table=11 FT /gene="SCO6695" FT /gene_synonym="SC4C6.05c" FT /product="putative membrane protein" FT /note="SC4C6.05c, possible membrane protein, len: 347 aa; FT similar to TR:O88067 (EMBL:AL031541) S.coelicolor possible FT membrane protein (319 aa), fasta scores; opt: 474 z-score: FT 403.9 E(): 3.6e-15, 37.9% identity in 354 aa overlap. FT Contains 4x PPXQ repeats starting at aa 46. Contains a FT hydrophobic, possible membrane-spanning region. Similar to FT TR:O88067 (EMBL:AL031541) S.coelicolor possible membrane FT protein (319 aa) (37.9% identity in 354 aa overlap). FT Contains possible hydrophobic membrane spanning region" FT /db_xref="InterPro:IPR018929" FT /db_xref="UniProtKB/TrEMBL:Q9XAN5" FT /protein_id="CAB45569.1" FT /translation="MTQATPPGWYPDPGQKNDGPATERWWDGTAWTDRVRPAGGAAAWA FT PPAQPPGQPPVQPPVQDTAAGPYPVHPGYPGIPVQPPSARRRRLRAGIAVAAAVAVLAG FT IGVGVYALTDDGSGGNDAGAAQQDRRGPDDRNDPFGDSGGGGGGGGEDGRSPAPDSPDR FT SEPPTIDSGSVTDALSGISLPIPDGWSGQELQVGAQVTSEDAYKCPGDTSKSCTKGGAY FT SAPAVLLKTEGDTAEEVAKADIEANAEESYGGESYGGITSHEELASEAVTVAGQKGYLV FT RWKAVTARGSDGFVESLAFPSPADSKRIVVVRFGVDTDQKQTVIDEITKGIEVDTSGGG FT GGNGQDV" FT CDS 276559..279240 FT /transl_table=11 FT /gene="SCO6696" FT /gene_synonym="SC4C6.06" FT /product="putative regulatory protein" FT /note="SC4C6.06, possible regulatory protein, len: 893 aa; FT similar to many putative regulators e.g. TR:Q55103 FT (EMBL:D13457) Streptomyces sp. ORF upstream of the FT cholesterol oxidase-cytochrome P450 operon (642 aa) fasta FT scores; opt: 347 z-score: 383.0 E(): 5.2e-14, 31.7% FT identity in 599 aa overlap. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop). Similar to FT (EMBL:AL035569) SC8D9.18 possible regulatory protein (1091 FT aa) (28.1% identity in 945 aa overlap)" FT /db_xref="GOA:Q9XAN4" FT /db_xref="InterPro:IPR011990" FT /db_xref="UniProtKB/TrEMBL:Q9XAN4" FT /protein_id="CAB45570.1" FT /translation="MTEVRRAGAVPASLWERDEEVATITRAVDTLCADRSSPGTLLEAR FT GEAGVGKTALLAETRRIAEARGCTGWSARGGETLRSVPFNVVRQLLQPALVSMLPEEAR FT EYLGDWYDIAGPALGIADPGERQADPRGVCDGLVAAVRRLARREWPLVLLIDDAHWADQ FT ETLRWLAALAERLDETSVLVVIARRPGDVSGDSARHLEAATAVGRPLAPLNALTPEATA FT GLTRATLGAHAEAAFCREVWAVTGGNPYETVELLAKVQDSELQPVEAEAAELRDLNRSA FT RGGGLVARLEQLGVDSTRFAWAAAILGGGITVDMVARLATLDRADAARCAELLRGARIL FT AVPDATAGQPSAGDLEFVHPLIATAVYNSIPDALRTAMHGIAAQLVTDSGLGAAAASRH FT LLKVHPDDDQEVVAQLREAAREHLAVGAPDAARRCLERALREPPLPESHARVLFELGCA FT TLLTAPATTIGHLRTALAMPGLEGEQRVDAVFRLSQALLHNDQLEEAVRTVEAEAARNP FT DPSARLRLQAAQYMWEGIHAGETSSPHRSARLAELAATCTGRDNAERALLILRGFDAMT FT HGESAEEVVELCDRALVNGRLAPGLGWTDTEWGLELPMMLASSYAYADRLDRAEALFTE FT ALRAYESAGWSGGHLSLAHAYVGLGHRRRGRLRDAEQSLRESLRIAERVGRGLPLYWSA FT TCNLIDTLLARGHVEEARTVAEQYGFAPPYPSTIVLPDPRPVRARLLLATGRTKEGINE FT LEAAEKAAAARGRHNPVVVPWATELARALAGEDPGRAARLATDARRQAERFGTDTAIGE FT ALRCAAALETGQRAVRLAAQAATYLEASPCQYEHAAARVEYGIAARSAAELNRGLALAE FT SCGADGLAARAREALAVVGRAG" FT misc_feature 276694..276717 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT repeat_region 277397..277427 FT /note="repeat 2; 31 bp imperfect inverted repeat" FT repeat_region complement(278822..278852) FT /note="repeat 2; 31 bp imperfect inverted repeat" FT repeat_region 278876..278909 FT /note="repeat 3; 33 bp imperfect inverted repeat" FT repeat_region complement(279023..279056) FT /note="repeat 3; 33 bp imperfect inverted repeat" FT CDS complement(279267..280394) FT /transl_table=11 FT /gene="SCO6697" FT /gene_synonym="SC4C6.07c" FT /gene_synonym="pcaL" FT /product="putative 3-oxoadipate enol-lactone FT hydrolase/4-carboxymuconolactone decarboxylase" FT /note="SC4C6.07c, pcaL, probable 3-oxoadipate enol-lactone FT hydrolase/4-carboxymuconolactone decarboxylase, len: 375 FT aa; similar to TR:O67982 (EMBL:AF003947), pcaL, Rhodococcus FT opacus 3-oxoadipate enol-lactone FT hydrolase/4-carboxymuconolactone decarboxylase (400 aa), FT fasta scores; opt: 401 z-score: 464.7 E(): 1.5e-18, 46.3% FT identity in 387 aa overlap the first approx. 260 aa is FT similar to SW:ELH2_ACICA (EMBL:AF009224), catD, FT Acinetobacter calcoaceticus 3-oxoadipate enol-lactonase II FT (266 aa) (35.1% identity in 248 aa overlap) while the FT remainder is similar to SW:DC4C_ACICA (EMBL:L05770), pcaC, FT 4-carboxymuconolactone decarboxylase. Highly similar to FT TR:O86608 (EMBL:AL031155) S.coelicolor probable FT 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone FT decarboxylase (449 aa) (43.3% identity in 439 aa overlap) FT which contains an approx. 70 residue insertion between the FT two domains of homology to the Acinetobacter enzymes. An FT alternative start codon is present at codon 4. Contains FT Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold" FT /db_xref="GOA:Q9XAN3" FT /db_xref="InterPro:IPR012790" FT /db_xref="UniProtKB/TrEMBL:Q9XAN3" FT /protein_id="CAB45571.1" FT /translation="MTTMLNHLSEGPASAPPLLLGPSLGTSYALWDAVAPELSVRHRVI FT RWDLPGHGGSRADLIGPGATVGDLADLVLALADSLGVERFAHAGVSLGGAVGLHLAVHH FT PERVSSLAVVCSSAHFNGAKPWEERAAQVRTEGLARLADSADARWFVPGFTVPRLVRDH FT READPGAYAACCDALAAFDLRERVGEISAPTLLVAGREDPATPPSHLREIADAVPGATL FT TEIPGASHLAPAERPEAVLTALRAHFDGAARRGMAVRREVLGDAHVDRAQARQSPFTAR FT FQDFISRYAWGEIWTDETLSRRERSMVTLTALVAHGHYEELAMHVRAARRNGLTPDEIG FT AVLLQTAVYCGVPAANSAFATAQRVLAEEADGTAE" FT misc_feature complement(279651..280271) FT /note="Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold, score 79.40, E-value 7.6e-20" FT CDS complement(280391..281755) FT /transl_table=11 FT /gene="SCO6698" FT /gene_synonym="SC4C6.08c" FT /gene_synonym="pcaB" FT /product="putative 3-carboxy-cis,cis-muconate FT cycloisomerase" FT /note="SC4C6.08c, pcaB, probable 3-carboxy-cis,cis-muconate FT cycloisomerase, len: 454 aa; similar to e.g. SW:PCAB_BRAJA FT (EMBL:Y10223), pcaB, 3-carboxy-cis,cis-muconate FT cycloisomerase (451 aa), fasta scores; opt: 996 z-score: FT 1027.1 E(): 0, 43.3% identity in 448 aa overlap. Contains FT Pfam match to entry PF00206 lyase_1, Lyase and PS00163 FT Fumarate lyases signature" FT /db_xref="GOA:Q9XAN2" FT /db_xref="HSSP:1Q5N" FT /db_xref="InterPro:IPR003031" FT /db_xref="UniProtKB/TrEMBL:Q9XAN2" FT /protein_id="CAB45572.1" FT /translation="MTSPAVPDPAGSEPDADTGLLAPGWTGSPAASATGDRAYLRALLD FT AEAALTRAQAALGLAPAEAADAVGAVAADPAAFDARSLAERARDGGNPVIPLVADLTKA FT VGEPYGPYVHRGATSQDILDTATMLVAARTLDLLLPDLARTERALARLAAEHRDTPMPG FT RTLTQHAVPTVFGLKAAGWRALVLDARDRITAVRDALPAQLGGAAGTLAAFEAYGATDP FT TALPAAYAGELGLRAPVLPWHTLRTPIADLAGTLAFTAGALGKIAVDVLTLSRTETGEV FT AEGGGGGSSAMPHKANPVRSTLIAAAARRAPQLAATLYGSLAAEDERPAGAWHAEWEPL FT RDLLRLTGGAARDAAELAEGLRVRPDAMRAHLGRTHGLIVSERLSAELAPVLGRARARE FT LLTELAARAYAEDRNLGELLAEVPELRGLDLAGPTDPARYTGAAATLTDRALERR" FT RBS complement(280400..280403) FT /note="possible RBS" FT misc_feature complement(280742..281422) FT /note="Pfam match to entry PF00206 lyase_1, Lyase, score FT 102.40, E-value 8.3e-28" FT misc_feature complement(280865..280894) FT /note="PS00163 Fumarate lyases signature" FT CDS complement(281752..282357) FT /transl_table=11 FT /gene="SCO6699" FT /gene_synonym="SC4C6.09c" FT /gene_synonym="pcaG" FT /product="protocatechuate 3,4-dioxygenase alpha subunit" FT /note="SC4C6.09c, pcaG, protocatechuate 3,4-dioxygenase FT alpha subunit, len: 201 aa; highly similar to pcaG FT (EMBL:AF109386) Streptomyces sp. 2065 protocatechuate FT 3,4-dioxygenase alpha subunit (201 aa), fasta scores; opt: FT 1144 z-score: 1272.2 E(): 0, 80.1% identity in 201 aa FT overlap" FT /db_xref="GOA:Q9XAN1" FT /db_xref="HSSP:1EOA" FT /db_xref="InterPro:IPR012786" FT /db_xref="UniProtKB/TrEMBL:Q9XAN1" FT /protein_id="CAB45573.1" FT /translation="MTKTDTGSPEQVLPTPSHTVGPFYGYALPFRGGEDIAPAGHPDTV FT TVHGYVYDGEGNPLPDALLELWGPDPGGAVPTADGSMRRDPASGGFLGRNGVEFTGFGR FT IQTDANGHWYARTLRPGARGRSAPYVSVCVFARGLLVHLFTRIYLPGDEAVLAADPLLA FT RVPAERRDTLVAGDEGHGTYRFNIRLQGEGETVFLEFQ" FT CDS complement(282364..283137) FT /transl_table=11 FT /gene="SCO6700" FT /gene_synonym="SC4C6.10c" FT /gene_synonym="pcaH" FT /product="protocatechuate 3,4-dioxygenase beta subunit" FT /note="SC4C6.10c, pcaH, protocatechuate 3,4-dioxygenase FT beta subunit, len: 257 aa; highly similar to pcaH FT (EMBL:AF109386) Streptomyces sp. 2065 protocatechuate FT 3,4-dioxygenase beta subunit (257 aa), fasta scores; opt: FT 1686 z-score: 1951.2 E(): 0 91.1% identity in 257 aa FT overlap. Contains Pfam match to entry PF00775 Dioxygenase, FT Dioxygenase and PS00083 Intradiol ring-cleavage FT dioxygenases signature" FT /db_xref="GOA:Q9XAN0" FT /db_xref="HSSP:3PCC" FT /db_xref="InterPro:IPR015889" FT /db_xref="UniProtKB/TrEMBL:Q9XAN0" FT /protein_id="CAB45574.1" FT /translation="MTLTQHDIDAEIAAEHAAYGKRVADGAPVEHHPRRDYAPYRSSVL FT RHPKQPPITIDVTKDPELVELASPAFGERDITDVDNDLTRQHTGEPVGERITVSGRLLD FT RHGKPVRGQLVEIWQANSAGRYAHQREQHDAPLDPNFTGVGRTLSDDDGFYRFTTVQPG FT PYPWRNHVNAWRPAHIHFSVFGSAFTQRLVTQMYFPNDPLFPYDPILQSVTDDAARQRL FT IATYDHSLSVPEFSLGYHWDIVLDGPNATWIEEGR" FT misc_feature complement(282421..283092) FT /note="Pfam match to entry PF00775 Dioxygenase, FT Dioxygenase, score -66.50, E-value 6.9e-07" FT misc_feature complement(282760..282846) FT /note="PS00083 Intradiol ring-cleavage dioxygenases FT signature" FT CDS complement(283156..284358) FT /transl_table=11 FT /gene="SCO6701" FT /gene_synonym="SC4C6.11c" FT /gene_synonym="pcaF" FT /product="beta-ketoadipyl-CoA thiolase" FT /note="SC4C6.11c, pcaF, beta-ketoadipyl-CoA thiolase, len: FT 400 aa; highly similar to pcaF (EMBL:AF117893) Streptomyces FT sp. 2065 beta-ketoadipyl-CoA thiolase (400 aa), fasta FT scores; opt: 2314 z-score: 2497.6 E(): 0, 87.4% identity in FT 397 aa overlap. Highly similar others from S.coelicolor FT e.g. (EMBL:AL049587), SC5F2A.14, S.coelicolor probable FT thiolase (404 aa) (40.2% identity in 423 aa overlap). FT Contains Pfam match to entry PF00108 thiolase, Thiolase, FT PS00099 Thiolases active site, PS00098 Thiolases FT acyl-enzyme intermediate signature and PS00737 Thiolases FT signature 2" FT /db_xref="GOA:Q9XAM9" FT /db_xref="HSSP:1M3K" FT /db_xref="InterPro:IPR002155" FT /db_xref="UniProtKB/TrEMBL:Q9XAM9" FT /protein_id="CAB45575.1" FT /translation="MKDVYLVDAVRTPFGKYNGGLSGVRPDDLAAHAIRELLGRTPGLD FT PSRIDDVYFGNANGAGEENRNVARMAALLAGLPTTVPGVTVNRLCASGLEAVIQAARAI FT AVGDASVALAGGVESMTRAPYVLPKPDRPFPAGHTEMYSTTLGWRMVNPAMDPQWTIPL FT GESAELIADKHGITREQQDEYALASHRKAARAQADGLFDAELAPVPVPRRKGDPVDFAA FT DECVRPDASLEAMAKLKPSFRKTDGTVTAGNASPLNDGAAALLLVDEEGLKATGREPLA FT RVSATGVSATDPQYFGLAPVEAVNRALARAGRDFADLDVLELNEAFAAQVLGCVAEWPE FT FDPAVLNPQGGAIALGHPLGASGARLAGTVAHQLARRGSGTGIATLCIGVGQGLALVLD FT R" FT misc_feature complement(283159..284358) FT /note="Pfam match to entry PF00108 thiolase, Thiolase, FT score 533.80, E-value 1.2e-156" FT misc_feature complement(283174..283215) FT /note="PS00099 Thiolases active site" FT misc_feature complement(283270..283320) FT /note="PS00737 Thiolases signature 2" FT misc_feature complement(284047..284103) FT /note="PS00098 Thiolases acyl-enzyme intermediate FT signature" FT CDS complement(284355..285008) FT /transl_table=11 FT /gene="SCO6702" FT /gene_synonym="SC4C6.12c" FT /gene_synonym="pcaJ" FT /product="putative 3-oxoadipate CoA-transferase subunit B" FT /note="SC4C6.12c, pcaJ, probable 3-oxoadipate FT CoA-transferase subunit B, len: 217 aa; highly similar to FT many CoA transferases e.g. SW:PCAJ_PSEPU (EMBL:M88763), FT PcaJ, Pseudomonas putida 3-oxoadipate CoA-transferase FT subunit B (212 aa), fasta scores; opt: 684 z-score: 774.2 FT E(): 0, 52.9% identity in 206 aa overlap. Highly similar to FT SW:SCOB_MYCTU (EMBL:Z95556), ScoB, Mycobacterium FT tuberculosis probable succinyl-CoA:3-ketoacid-coenzyme A FT transferase subunit B (218 aa) (73.9% identity in 207 aa FT overlap). Contains Pfam match to entry PF01144 CoA_trans, FT Coenzyme A transferase" FT /db_xref="GOA:Q9XAM8" FT /db_xref="HSSP:1O9L" FT /db_xref="InterPro:IPR004165" FT /db_xref="UniProtKB/TrEMBL:Q9XAM8" FT /protein_id="CAB45576.1" FT /translation="MSWTREQMAARAALELEDGQYVNLGIGLPTLIPNYLPDGVEVTLE FT SENGILGTGRYPTDAEVDPDLINAGKETVTVRPGAAFFDSALSFGMIRGGHIDVAVLGA FT MQVSASGDLANWAIPGKMITGIGGAMDLVHGARTVIVVMTHTAKDGSPKILKKCALPLT FT GKACVDRVITDLGVLDVTGDGLVLVETAPGVSVDEVVARTDAELVVAKSAEGLK" FT RBS complement(284366..284370) FT /note="possible RBS" FT misc_feature complement(284400..284999) FT /note="Pfam match to entry PF01144 CoA_trans, Coenzyme A FT transferase, score 354.50, E-value 1.2e-102" FT CDS complement(285008..285790) FT /transl_table=11 FT /gene="SCO6703" FT /gene_synonym="SC4C6.13c" FT /gene_synonym="pcaI" FT /product="putative 3-oxoadipate CoA-transferase subunit A" FT /note="SC4C6.13c, pcaI, probable 3-oxoadipate FT CoA-transferase subunit A, len: 260 aa; highly similar to FT many CoA transferases e.g. SW:PCAI_PSEPU (EMBL:M88763), FT pcaI, Pseudomonas putida 3-oxoadipate CoA-transferase FT subunit A (231 aa), fasta scores; opt: 337 z-score: 379.8 FT E(): 8e-14, 42.6% identity in 242 aa overlap. Highly FT similar to SW:SCOA_MYCTU (EMBL:Z95556), scoA, Mycobacterium FT tuberculosis probable succinyl-CoA:3-ketoacid-coenzyme A FT transferase subunit A (248 aa) (69.9% identity in 249 aa FT overlap). Contains Pfam match to entry PF01144 CoA_trans, FT Coenzyme A transferase and PS01273 CoA transferases FT signature 1" FT /db_xref="GOA:Q9XAM7" FT /db_xref="HSSP:1O9L" FT /db_xref="InterPro:IPR004163" FT /db_xref="UniProtKB/TrEMBL:Q9XAM7" FT /protein_id="CAB45577.1" FT /translation="MDKVVATAGAAVADVADGASLAVGGFGLSGVPNVLIQALYERGTG FT GLSVVSNNCGAMESGLAVLLAAGRIARVTGSYIGANKEFARQYLGGELEVEMIPQGTLA FT ERLRAGGAGIPAFYTPAGVGTQVADGGLPWRYDGSGGVALASPPKEVREFDGTQYVLER FT GIRTDFALVRAAKGDRHGNLVFAKSSRNFNPLAATAGRVTIAEVEELVEPGAIDPDAVH FT LPGIFVQRVVALTPEQATDKKIERRTISAPPARGTVTS" FT misc_feature complement(285086..285784) FT /note="Pfam match to entry PF01144 CoA_trans, Coenzyme A FT transferase, score 293.60, E-value 2.4e-84" FT repeat_region 285452..285484 FT /note="repeat 4; 33 bp imperfect inverted repeat" FT misc_feature complement(285695..285742) FT /note="PS01273 CoA transferases signature 1" FT CDS 286000..286464 FT /transl_table=11 FT /gene="SCO6704" FT /gene_synonym="SC4C6.14" FT /product="putative transcriptional regulator" FT /note="SC4C6.14, possible transcriptional regulator, len: FT 154 aa; similar to e.g. SW:MEXR_PSEAE (EMBL:U23763), MexR, FT Pseudomonas aeruginosa multidrug resistance operon FT repressor (147 aa), fasta scores; opt: 180 z-score: 234.3 FT E(): 1e-05, 30.7% identity in 114 aa overlap. C-terminal FT half shows highest similarity with other transcriptional FT regulators. C-terminal half similar to others from S. FT coelicolor e.g. TR:O86554 (EMBL:AL031350) S. coelicolor FT hypothetical protein (143 aa) (31.6% identity in 98 aa FT overlap). Could be a divergently-transcribed FT transcriptional regulator for the pca operon upstream of FT this CDS (very hypothetical). Contains Pfam match to entry FT PF01047 MarR, MarR family" FT /db_xref="GOA:Q9XAM6" FT /db_xref="InterPro:IPR000835" FT /db_xref="UniProtKB/TrEMBL:Q9XAM6" FT /protein_id="CAB45578.1" FT /translation="MAAVDLATHPGHLARRLQQAHYLLWNTMVSEETTSPQYAVLNALV FT AEPGLDQRTVGERVGLDRSTIAEVVSRLGRRGLLDKVRDPQDGRRSLLRLTDEGLRVHR FT RLGVRIARMNQVFLAPLAADEQAVFFDLIRRVADAAEGLRNPAEPAVAPG" FT misc_feature 286096..286407 FT /note="Pfam match to entry PF01047 MarR, MarR family, score FT 72.40, E-value 9.5e-18" FT CDS complement(286480..287457) FT /transl_table=11 FT /gene="SCO6705" FT /gene_synonym="SC4C6.15c" FT /product="putative secreted protein" FT /note="SC4C6.15c, probable secreted protein, len: 325 aa; FT similar to TR:O30567 (EMBL:AF011544), yecC, Bacillus FT subtilis hypothetical protein (331 aa), fasta scores; opt: FT 278 z-score: 312.3 E(): 4.6e-10, 25.9% identity in 305 aa FT overlap. Also similar to yerB, which is identical to yecC. FT Contains a probable N-terminal signal sequence" FT /db_xref="UniProtKB/TrEMBL:Q9XAM5" FT /protein_id="CAB45579.1" FT /translation="MRRGTRRGRCAALLTAAVAVSLGAAGCTAGPGAQDDGRASTAPVP FT ERSHSAAPASGPVLAVKVDNVRAARPQTGLEDADVVYAEPVEAGLSRLMAIYATELPES FT VGPVRSARESDLELLGQFDRPVLAFSGAQSKLLPIIDKAPLRAEPASEDSDAYVRAGDR FT QAPHNLYLRPDELLGKPSGAAALTTGFTYGKAPAGGRAESSHTVRYPSASFAFTWSDSR FT DRWLVSMDGSPARTADGGRLAPATVVVQHVRVRESDFRDFRGSNSPYVESVGSGEAEVL FT RDGRVYDATWKRGAAEDGTTYTTGDGKPLNFAEGQVWVVFAGRS" FT repeat_region complement(287095..287127) FT /note="repeat 4; 33 bp imperfect inverted repeat" FT RBS 287652..287656 FT /note="possible RBS" FT CDS 287668..288858 FT /transl_table=11 FT /gene="SCO6706" FT /gene_synonym="SC4C6.16" FT /product="putative glutathione-dependent aldehyde FT dehydrogenase" FT /note="SC4C6.16, probable glutathione-dependent aldehyde FT dehydrogenase, len: 396 aa; similar to many e.g. FT SW:FADH_METMR (EMBL:L33464), fdh, Methylobacter marinus FT glutathione-dependent formaldehyde dehydrogenase (424 aa), FT fasta scores; opt: 1126 z-score: 1211.8 E(): 0, 44.1% FT identity in 406 aa overlap. Similar to (EMBL:AL049485), FT SC6A5.31c, S.coelicolor probable zinc-binding alcohol FT dehydrogenase (363 aa) (31.0% identity in 316 aa overlap). FT Contains Pfam match to entry PF00107, adh_zinc, FT Zinc-binding dehydrogenases and PS00059 Zinc-containing FT alcohol dehydrogenases signature" FT /db_xref="GOA:Q9XAM4" FT /db_xref="HSSP:1F8F" FT /db_xref="InterPro:IPR013154" FT /db_xref="UniProtKB/TrEMBL:Q9XAM4" FT /protein_id="CAB45580.1" FT /translation="MKAVTWQGKRDVRVEEVPDPKIQEPTDAVIRVTSSGLCGSDLHLY FT EVLTPFMTPGDILGHEPMGIVEEVGPEVTNLKPGDRVVVPFQIACGHCYMCDTGLPTQC FT ETTQVTGEGMGAPLFGYTRLYGAIPGGQAEYLRVPQAQFGPIKVPEGPADDRFVYLSDV FT LPTAWQAVEYAAVPQGGSLAVLGLGPIGDMACRIARLKGIDKVFGVDLVPERLERARER FT GVETFDLRSFDNEKELVSAIQDRTGGRGPDAVIDAVGTEAHGGAVAKLVQQTAAVLPRA FT IGGPLAERFSIDRLAALYTAIDLVRRGGTISLSGVYGGMADPMPMLTMFDKQIQLRMGQ FT ANVRRWSDEIVPYLTDDDPLGVDGFATHRMPLADAPHAYEMFQKKQDGAVKVLMQP" FT misc_feature 287671..288852 FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score 108.90, E-value 1e-28" FT misc_feature 287842..287886 FT /note="PS00059 Zinc-containing alcohol dehydrogenases FT signature" FT repeat_region 288294..288340 FT /note="repeat 5; 47 bp imperfect inverted repeat" FT CDS complement(288874..289941) FT /transl_table=11 FT /gene="SCO6707" FT /gene_synonym="SC4C6.17c" FT /product="putative DNA ligase" FT /note="SC4C6.17c, possible DNA ligase, len: 355 aa; similar FT to many archaeal and eukaryotic DNA ligases e.g. to the FT C-terminal half of SW:DNLI_ACIAM (EMBL:X63438), lig, FT Acidianus ambivalens DNA ligase (600 aa), fasta scores; FT opt: 240 z-score: 283.0 E(): 2e-08, 24.7% identity in 377 FT aa overlap. The majority of similar genes have an FT additional N-terminal region of 210-220 aa relative to this FT sequence. The putative DNA ligase TR:O28549 (EMBL:AE000984) FT from Archaeoglobus fulgidus is an exception (313 aa). FT Highest similarity is to TR:O69698 (EMBL:AL022121) FT Mycobacterium tuberculosis possible DNA ligase (358 aa) FT (60.4% identity in 361 aa overlap). Contains Pfam match to FT entry PF01068 DNA_ligase, DNA ligase and PS00697 FT ATP-dependent DNA ligase AMP-binding site" FT /db_xref="GOA:Q9XAM3" FT /db_xref="InterPro:IPR012340" FT /db_xref="UniProtKB/TrEMBL:Q9XAM3" FT /protein_id="CAB45581.1" FT /translation="MDLPVMPPVKPMLAKSVAKIPPGMHYEAKWDGFRAIVYRDGDEVE FT LGSRTGKPLTRYFPELVVAVRERLPERCVVDGEIVIARDGHLDFDALTERIHPADSRVR FT TLAERTPASLVAFDLLALDDASLLDVGLADRRALLVRALSGVTPPVHVAPATDDIEVAR FT RWFEQYEGAGLDGVVAKPLDLRYRQDERAMYKIKHERTADVVVAGYRFHKSGPVVGSLL FT LGLYDDRGLLQHVGVSAAFTMKRRAELVAELEPLRMDDARGHPWAAWAEEAAHESARLP FT GAPSRWSGKKDLSWVPLRPERVVEVAYDHMENGARFRHTARFRRWRPDRTPESCTYAQL FT EEPVRYDLAEILGGP" FT misc_feature complement(289105..289920) FT /note="Pfam match to entry PF01068 DNA_ligase, DNA ligase, FT score 95.70, E-value 9e-25" FT repeat_region complement(289719..289765) FT /note="repeat 5; 47 bp imperfect inverted repeat" FT misc_feature complement(289837..289863) FT /note="PS00697 ATP-dependent DNA ligase AMP-binding site" FT RBS 290145..290148 FT /note="possible RBS" FT CDS 290154..290492 FT /transl_table=11 FT /gene="SCO6708" FT /gene_synonym="SC4C6.18" FT /product="putative membrane protein" FT /note="SC4C6.18, possible membrane protein, len: 112 aa; FT unknown function, probable CDS suggested by positional base FT preference, GC frame plot and amino acid composition. FT Contains hydrophobic, possible membrane-spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9XAM2" FT /protein_id="CAB45582.1" FT /translation="MASPYINAPLTPVRPRMYASALAKVVWTLVPIVTLGLAAAVPFVV FT AAVKGVVKPWLAGAYVVGEIAVFSVAIAISPDPDDTNPFPGFLMVLLIITAATHTALLD FT NDRISVGK" FT CDS 290584..291609 FT /transl_table=11 FT /gene="SCO6709" FT /gene_synonym="SC4C6.19" FT /product="conserved hypothetical protein" FT /note="SC4C6.19, conserved hypothetical protein, len: 341 FT aa; similar to hypothetical proteins from Mycobacterium FT tuberculosis, Mycobacterium leprae and Bacillus subtilis FT e.g. TR:O69697 (EMBL:AL02212) Mycobacterium tuberculosis FT hypothetical protein (346 aa), fasta scores; opt: 1313 FT z-score: 1504.6 E(): 0, 59.2% identity in 336 aa overlap. FT Similarity is confined to the N-terminal end in cases where FT the similar protein is longer then this one e.g. TR:O05865 FT (EMBL:Z95209) Mycobacterium tuberculosis hypothetical FT protein (759 aa) (28.3% identity in 336 aa overlap). Also FT similar to SC1E6.07 (EMBL:AL033505) S.coelicolor FT hypothetical protein (319 aa) (35.8% identity in 288 aa FT overlap)" FT /db_xref="GOA:Q9XAM1" FT /db_xref="InterPro:IPR002755" FT /db_xref="UniProtKB/TrEMBL:Q9XAM1" FT /protein_id="CAB45583.1" FT /translation="MAEAVELEAGGRSVRLSSPGKVFFPEHGYTKLDVARYYQAVAPGV FT LRALRERPTTLQRYPDGITGEWFYQKRAPKGMPDWIPTAHITFPSGRSADEMCPTEEAA FT VLWAAQYGTLTFHPWPVRRDDVDHPDELRIDLDPQPGTDYDDAARAAHELRAVLEEFGG FT LRGWPKTSGGRGIHVFVPIEPRWTFTQVRRAAIAVGREMERRMPERVTIKWWKEERGER FT IFIDYNQTARDRTIASAYSVRPRPNAPVSAPLTWDEVGVAHPRDFDITTMPARFAELGD FT VHAGMDDTRYSLDALLELATKDEHDHGLGDLPYPPEYPKMPGEPSRVQPSRARKKAPGP FT D" FT CDS complement(291626..293815) FT /transl_table=11 FT /gene="SCO6710" FT /gene_synonym="SC4C6.20c" FT /product="putative glycosyl hydrolase" FT /note="SC4C6.20c, possible glycosyl hydrolase, len: 729 aa; FT weakly similar to part of several glycosyl hydrolases e.g. FT SW:GUXB_CELFI (EMBL:L02544), CenD, Cellulomonas fimi FT endoglucanase D precursor (1090 aa), fasta scores; opt: 235 FT z-score: 236.1 E(): 8.1e-06, 29.5% identity in 285 aa FT overlap and TR:O30678 (EMBL:AF014950), ChiA, FT Stenotrophomonas maltophilia chitinase A (700 aa) (28.6% FT identity in 262 aa overlap). Contains 3x degenerate FT repeats of DTTAPXTSATVXGTKNADGAYVGSATVTVXAXDEGGSGVXXIE FT YALGADGAWXAYTXPVXVDXVGEHTVRYRAXDKAGNXAEEKSVXF between aa FT 146 and 424. Weakly similar to the C-terminal half of FT TR:O69947 (EMBL:AL023862) S. coelicolor hypothetical FT protein (1238 aa) (23.5% identity in 737 aa overlap). The FT upstream ORF SC4C6.21c has significant similarity to the FT remainder of this hypothetical protein. Contains Pfam match FT to entry PF00127 copper-bind, Copper binding proteins, FT plastocyanin/azurin family" FT /db_xref="GOA:Q9XAM0" FT /db_xref="HSSP:1QHQ" FT /db_xref="InterPro:IPR003410" FT /db_xref="UniProtKB/TrEMBL:Q9XAM0" FT /protein_id="CAB45584.1" FT /translation="MWAALLAGLLMVLGLQATSASGQPAKAPAAAAADQVLTWTAGDDI FT TKYASAPETAVAGPATIVFENSEATGNTTGMPHTLTFMTSDPAYNQDVQLNILANPNDA FT EGGKHTAEVTLTPGTYMYHCTIPGHGQMTGVLVVTEGGGGEDTTAPATSAEVGGTQNAD FT GAYVGSATVSIAATDEGGSGVERIEYALGADGAWQPYTTPVVVDQVGEHTVRYRAFDKA FT GNAAEEKSVTFAVAAPDTDDTTAPETSATVSGDKNAEGAYIDMATVTVTASDTGSGVNT FT IEYAVGDGAWTAYTAPVMVHEVGEHTVRYRATDKAGNVAAEKSVAFTVAAAPPQDTTPP FT VTGATVDGTKNSDGAYVGSAKVTVNAADEGGSGVAGVEYSLDAGPYLAYTDPVIVDRVG FT RHTVAYRASDKAGNTSEPLTVDFTVVSGQVPPPPCPEYDERQTVIVGTVDSGVPNRVTN FT NRCRINEMIEDEKEWTSQALFLKHVREVMDGLLDEGVVDKREYRAINKAAKQSKIGQPG FT QTEGYRTILDGSQESFAKWEQVGGGSFGLNPDGSITSSTSTPGMGMLWFPE |