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EBI DbfetchID AL939125; SV 1; linear; genomic DNA; STD; PRO; 295150 BP. XX AC AL939125; AL009199; AL009204; AL020958; AL021409; AL021411; AC AL021529-AL021530; AL022268; AL022374; AL031031; AL590983; AL596162; XX DT 25-OCT-2002 (Rel. 73, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 4) XX DE Streptomyces coelicolor A3(2) complete genome; segment 22/29 XX KW . XX OS Streptomyces coelicolor OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Streptomycineae; Streptomycetaceae; Streptomyces. XX RN [1] RP 1-295150 RA Bentley S.D.; RT ; RL Submitted (09-MAY-2002) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Streptomyces sequencing team, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL sdb@sanger.ac.uk XX RN [2] RX DOI; 10.1038/417141a RX PUBMED; 12000953. RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L., RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H., RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E., RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D., RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.; RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor RT A3(2)"; RL Nature 417(6885):141-147(2002). XX DR EMBL-CON; AL645882. DR RFAM; RF00379; ydaO-yuaA. XX FH Key Location/Qualifiers FH FT source 1..295150 FT /organism="Streptomyces coelicolor" FT /strain="A3(2)" FT /mol_type="genomic DNA" FT /db_xref="taxon:1902" FT RBS 179..184 FT /note="possible RBS upstream of SC7C7.06" FT CDS 190..1053 FT /transl_table=11 FT /gene="SCO5751" FT /gene_synonym="SC7C7.06" FT /product="putative membrane protein" FT /note="SC7C7.06, putative membrane protein, len: 287 aa. FT Contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:O86811" FT /protein_id="CAA19852.1" FT /translation="MSNGKSPEDERPIEDVSQDAPDDVSEEARPSVGHALRQARIAAGL FT TVDDITTATRVRIAIVHAIEADDFAPCGGDVYARGHIRTLAKAVGLDPAELLARFDAEH FT GGRPAPTPAAPLFEAERIRPERRGPNWTAAMVAAIVAVIGFVGFTFVKGGDDGGNEASV FT AEGAQPSSGESASSSAKPKKPADPKPEPSDSAIAAAPADKVTVKVSATEGRSWISAQDH FT NGRLLFDGLLKQGDSKTFQDNEKVKLVLGDAGAIQLYVNGKKIEDDFRPGAVERLTYTK FT GDPQVG" FT CDS 1145..2626 FT /transl_table=11 FT /gene="SCO5752" FT /gene_synonym="SC7C7.07" FT /product="conserved hypothetical protein SC7C7.07" FT /note="SC7C7.07, unknown, len: 493 aa; similar to many FT members of the UPF0004 family e.g. YLIG_ECOLI (441 aa), FT fasta scores; opt: 642 z-score: 947.7 E(): 0, 31.8% FT identity in 487 aa overlap. Contains PS01278 FT Uncharacterized protein family UPF0004 signature. Also FT similar to S. coelicolor SC4H2.08, fasta scores; E(): FT 9.1e-23, 30.3% identity in 445 aa overlap" FT /db_xref="GOA:O86812" FT /db_xref="InterPro:IPR013848" FT /db_xref="UniProtKB/Swiss-Prot:O86812" FT /protein_id="CAA19853.1" FT /translation="MPESRTVALVTLGCARNEVDSEELAGRLEADGWKLVDDAEEADVA FT VVNTCGFVEAAKKDSVDALLEANDLKGHGRTQAVVAVGCMAERYGKELADALPEADGVL FT GFDDYADISDRLQTILNGGIHAAHTPRDRRKLLPISPAERQEAGAAVALPGHGPTDLPE FT GVAPASGPRAPLRRRLDGSPVASVKLASGCDRRCSFCAIPSFRGSFISRRPSDVLNETR FT WLAEQGVKEIMLVSENNTSYGKDLGDIRLLESLLPNLAEVDGIERVRVSYLQPAEMRPG FT LIDVLTSTEKVAPYFDLSFQHSAPNVLRAMRRFGDTDRFLELLDTIRSKAPEAGVRSNF FT IVGFPGESEADLAELERFLNHARLDAIGVFGYSDEEGTEAATYGDKLDEDVVAERLARV FT SRLAEELVSQRADERVGATVRVLVESVDPAGEGDGVRGRAEHQAPETDGQVLLTSGAGL FT SVGRMVDAKVVGTEGVDLVAEPLLGSPEWSEEAGR" FT misc_feature 1703..1765 FT /note="PS01278 Uncharacterized protein family UPF0004 FT signature" FT RBS 2610..2615 FT /note="possible RBS upstream of SC7C7.08" FT CDS 2623..3414 FT /transl_table=11 FT /gene="SCO5753" FT /gene_synonym="pgsA" FT /product="phosphatidylglycerophosphate synthase" FT /note="SC7C7.08, pgsA, probable FT phosphatidylglycerophosphate synthase, len: 263 aa; FT integral membrane protein similar to many e.g. PGSA_BACSU FT CDP-diacylglycerol--glycerol-3-phosphate FT 3-phosphatidyltransferase (193 aa), fasta scores; opt: 304 FT z-score: 312.1 E(): 3.8e-10, 38.0% identity in 187 aa FT overlap. Contains PS00379 CDP-alcohol FT phosphatidyltransferases signature. FramePlot suggests FT start site at V40, similarities start downstream of this. FT Upstream start site chosen by HMM, corroborated by RBS. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="GOA:O86813" FT /db_xref="InterPro:IPR004570" FT /db_xref="UniProtKB/TrEMBL:O86813" FT /protein_id="CAA19854.1" FT /translation="MTGVPASAAGGSSSARRTGPRGASGAAQEPAGRTTSGGAVERDAG FT ERRGATEGGAGARGGKIAAAAVNQASVWNVANLLTMLRLLLVPAFVALMLGNGGYDPAW FT RSFAWAAFAIAMITDLFDGHLARTYNLVTDFGKIADPIADKAIMGAALICLSALGDLPW FT WVTAVILGRELGITVLRFVVIRYGVIPASRGGKLKTLIQGIAVGMYVLALTGPLATLRF FT WVMAAAVVLTVATGLDYVKQAIVLRRRGIAERRAALKETEV" FT misc_feature 2986..3054 FT /note="PS00379 CDP-alcohol phosphatidyltransferases FT signature" FT RBS 3397..3402 FT /note="possible RBS upstream of SC7C7.09" FT CDS 3411..3956 FT /transl_table=11 FT /gene="SCO5754" FT /gene_synonym="SC7C7.09" FT /product="conserved hypothetical protein SC7C7.09" FT /note="SC7C7.09, unknown, len: 181 aa; similar to FT competence damage induced proteins of B. subtilis and FT Streptococcus pneumoniae e.g. CINA_STRPN putative FT competence-damage protein (418 aa), fasta scores; opt: 304 FT z-score: 431.6 E(): 8.4e-17, 35.8% identity in 165 aa FT overlap. Contains probable coiled-coil from 133 to 175" FT /db_xref="InterPro:IPR008136" FT /db_xref="UniProtKB/TrEMBL:O86814" FT /protein_id="CAA19855.1" FT /translation="MSSTAADVVRLLTVRGETLAVAESLTGGMVAATLTAVPGASKAFR FT GSVTAYATELKRELLGVDGELLAARGAVDAQVAAQMAAGVRTALGADWGIATTGVAGPD FT PQDGQPVGTVFVAVDGPFRAEQGCADGGKVEALRLNGDRAEIRMESVQSVLALLLRELA FT SEQTGNERAQDTERNGGF" FT RBS 4051..4056 FT /note="possible RSB upstream of SC7C7.10" FT CDS 4066..4446 FT /transl_table=11 FT /gene="SCO5755" FT /gene_synonym="SC7C7.10" FT /product="hypothetical protein SC7C7.10" FT /note="SC7C7.10, unknown, len: 126 aa; highly similar to M. FT tuberculosis TR:O33287 (EMBL:AL008967) possible FT transcriptional regulator MTV002.10C (Rv2745c) (112 aa), FT fasta scores; opt: 300 z-score: 454.0 E(): 4.7e-18, 60.5% FT identity in 86 aa overlap" FT /db_xref="GOA:O86815" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:O86815" FT /protein_id="CAA19856.1" FT /translation="MILLRRLLGDVLRRQRQRQGRTLREVSSSARVSLGYLSEVERGQK FT EASSELLSAICDALDVRMSELMREVSDELALAELARSAAATPSETVPAPVRPMLGSVSV FT TGVPPERVTIKAPAEAVDVVAA" FT RBS 4641..4645 FT /note="possible RBS upstream of SC7C7.11" FT CDS 4651..5121 FT /transl_table=11 FT /gene="SCO5756" FT /gene_synonym="SC7C7.11" FT /product="hypothetical protein SC7C7.11" FT /note="SC7C7.11, unknown, len: 156 aa; similar to members FT of the Dps family e.g. FTPA_HAEDU fine tangled pili major FT subunit (24 KD surface protein) (189 aa), fasta scores; FT opt: 278 z-score: 370.3 E(): 2.2e-13, 34.4% identity in 151 FT aa overlap PS_ECOLI DNA protection during starvation FT protein (166 aa) and, fasta scores; opt: 220 z-score: 261.2 FT E(): 2.6e-07, 26.8% identity in 153 aa overlap. Contains FT PS00818 Dps protein family signature 1" FT /db_xref="GOA:O86816" FT /db_xref="HSSP:1O9R" FT /db_xref="InterPro:IPR012347" FT /db_xref="UniProtKB/TrEMBL:O86816" FT /protein_id="CAA19857.1" FT /translation="MYVVKSPLSDADLKTVSEALQGALVDLVDLALVAKQIHWNVVGPR FT FRSVHLQLDELVGTARTHSDTVAERASALGVSPDGRAATVAVGSGIDVTPEGWVDDTTA FT VQTVVDALGAVIGRMRERIAASGEPDPVSQDIFIQITADLEKQHWMFQAENG" FT misc_feature 4762..4812 FT /note="PS00818 Dps protein family signature 1" FT CDS 5128..5394 FT /transl_table=11 FT /gene="SCO5757" FT /gene_synonym="SC7C7.12" FT /product="hypothetical protein SC7C7.12" FT /note="SC7C7.12, questionable ORF, len: 88 aa" FT /db_xref="UniProtKB/TrEMBL:O86817" FT /protein_id="CAA19858.1" FT /translation="MVSARTARRAAALGLGVLWWWAVLRLALEPGAGVLEGAVAVGGWG FT LSVLPVHCVPRRRAAGALGAGRWRRALRGARTRGAATTLPDGR" FT CDS 5450..5824 FT /transl_table=11 FT /gene="SCO5758" FT /gene_synonym="SC7C7.13" FT /product="putative transcriptional regulator" FT /note="SC7C7.13, possible transcriptional regulator, len: FT 124 aa; similar to several putative transcriptional FT regulators fomr M. tuberculosis e.g. TR:O53478 FT (EMBL:AL021899) putative regulator MTV018.21 (Rv2034) (107 FT aa), fasta scores; opt: 178 z-score: 327.3 E(): 5.4e-11, FT 40.7% identity in 81 aa overlap. Contains probable FT helix-turn-helix motif at aa 34-55 (Score 999, +2.59 SD)" FT /db_xref="GOA:O86818" FT /db_xref="InterPro:IPR001845" FT /db_xref="UniProtKB/TrEMBL:O86818" FT /protein_id="CAA19859.1" FT /translation="MVEEAEAGTDRLFQALADLTRRDILRRCVRDDLSVSRLAEAYPMS FT FAAVQKHVAVLERAGLVVKERCGREQLVRTDPDALGRARRALDELEAAWRGRVERMSGL FT LAEAPEAGSAARQPTEGQSR" FT RBS 5808..5812 FT /note="possible RSB upstream of SC7C7.14" FT CDS 5821..6306 FT /transl_table=11 FT /gene="SCO5759" FT /gene_synonym="SC7C7.14" FT /product="hypothetical protein SC7C7.14" FT /note="SC7C7.14, unknown, len: 161 aa" FT /db_xref="GOA:O86819" FT /db_xref="InterPro:IPR013538" FT /db_xref="UniProtKB/TrEMBL:O86819" FT /protein_id="CAA19860.1" FT /translation="MSVTSLDKDLDNLTLTLVADFAAPVERVWQLWSDPRQLERWWGPP FT AYPATVEEHDLTPGGDVTYFMTGPEGEKFRGWWRVATVDAPRSLEFTDGFADEDGVPNA FT AMPTTANRVTLTERDGGTRMEMRAVFDTREQMEQLMTMGMAEGLREAAGQMDALLAA" FT CDS complement(6344..7174) FT /transl_table=11 FT /gene="SCO5760" FT /gene_synonym="SC7C7.15c" FT /product="DNA glycosylase" FT /note="SC7C7.15c, probable DNA glycosylase involved in DNA FT repair, len: 276 aa; similar to e.g. END8_ECOLI FT endonuclease VIII (EC 3.2.-.-) (263 aa), fasta scores; opt: FT 384 z-score: 449.2 E(): 8.7e-18, 34.5% identity in 278 aa FT overlap" FT /db_xref="GOA:O86820" FT /db_xref="HSSP:1K82" FT /db_xref="InterPro:IPR012319" FT /db_xref="UniProtKB/Swiss-Prot:O86820" FT /protein_id="CAA19861.1" FT /translation="MPEGDTVWQAARRLHDALAGRVLTRSDFRVPRYATVDLTGRTVLD FT VTPRGKHLLTRVEGGLTVHSHLRMDGSWKVFAPGQRWSGGPAHQIRVILGTADRTAVGY FT RLPVLDILRTAEEQRAVGHLGPDLLGPDWDPERALDNLRADPPRALGEALLDQRNLAGI FT GNVYKSELCFLLGVTPWLPVGELPADRAARLPTLAKKLLEANRDRPVRRTTGLRGQDLF FT VYGRAPRPCLRCGTSVRVADQGDGSRERPTYWCPTCQAGPAPRPGGRTGVRPRR" FT CDS complement(7193..12265) FT /transl_table=11 FT /gene="SCO5761" FT /gene_synonym="SC7C7.16c" FT /product="putative ATP-dependent DNA helicase" FT /note="SC7C7.16c, probable ATP dependent DNA helicase, len: FT 1690 aa; highly similar to e.g. LHR_ECOLI probable FT atp-dependent helicase lhr (EC 3.6.1.-) (1538 aa), fasta FT scores; opt: 2361 z-score: 3018.1 E(): 0, 48.6% identity in FT 1435 aa overlap. Contains PS00017 ATP/GTP-binding site FT motif A (P-loop) and Pfam matches to entry DEAD PF00270, FT DEAD and DEAH box helicases, score 30.04 and to entry FT helicase_C PF00271, Helicases conserved C-terminal domain, FT score 42.17" FT /db_xref="GOA:O86821" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:O86821" FT /protein_id="CAA19862.1" FT /translation="MVSSAHRALDGFSPATRGWFTGAFSAPTSAQAGAWQAISQGSDVL FT VVAPTGSGKTLAAFLAALDQLTSTPPPADPKKRCRVLYVSPLKALAVDVERNLRSPLTG FT IRQESVRLGLPEPEVKVGIRSGDTPAAERRALSTRPPDILITTPESLFLMLTSATRDAL FT TGIETVILDEVHAVAGTKRGAHLALTLERLDELLPKPARRIGLSATVRPVDEVARFLAP FT RGRVEIVQPESGKEFDLSVVVPVEDLGELGGSPVAEGNEGAERPSIWPHVEERITDLVQ FT SHRSTIVFANSRRLAERLCNRLNEIAYERATGEPLDEHHSPAELMGGSGAAQGAPPVIA FT RAHHGSVSKEQRALVEEDLKAGRLPAVVATSSLELGIDMGAVDLVVQVESPPSVASGLQ FT RVGRAGHQVGAVSTGVVFPKYRGDLVQSAVVTERMRSGAIEALRIPANPLDVLAQQLVA FT MTALDTWQVDDLLTTVRRAAPFASLPESAFTAVLDMLAGRYPSDAFAELRPRVVWDRVA FT GTVTGRPGAQRLAVTSGGTIPDRGLFGVFLAGADPKKGGGRVGELDEEMVYESRVGDVF FT TLGTSSWRIEDITRDRVLVSPAPGVPGRLPFWKGDQLGRPLELGRALGAFLREVGSLSK FT EDARLRLVTAGLDAWAADNVLSYLDEQREACGHVPDDRTIVVERFRDELGDWRVVVHSP FT FGAQVHAPWALALGARLSERYGMDAQVMHADDGIVLRLPDADLMGLDFLDQDPAKPGLE FT YDAEKAPVGAADVVFDKGEVDRVVTDQVGGSALFASRFRECAARALLLPRRSPGKRTPL FT WQQRQRAAQLLEVASEYGSFPIVLEAVRECLQDVFDVPGLVELMGDVETRKVRLVEVTT FT PEPSPFARSLLFGYVAQFLYEGDSPLAERRAAALSLDSRLLAELLGQAELRELLDAEVL FT TELERELQWLTEDRRIKDPEGVADLLRMLGPLTDAELAERGAEPQWAPELAAARRAIRV FT RIAGADHWAAIEDAGRLRDALGTALPVGVPEAFTEPVKDPLGDLLARHARTHGPFTSVT FT AAARFGLGVAVTEGALQRLAGSGRVVQGEFHPAGIGQEWCDATVLRRLRRRSLAALRHE FT LEPVAPAALGQFLPQWQHIGKGHTLRGIDGLVRAVEQLQGASVPASALEKLVLPSRVAH FT YNPAMLDELTAAGEVVWAGAGSLPGKDGWVSLYLADAAPLLLPPPHPLETTALHESVLS FT TLSGGYGLFFRQIADQVRATTHPEATDPQLADALWDLAWSGRLTNDTLAPLRSVLGSGR FT TAGSTAHRAKRAVPRGRYGSLTAAARPASRTGPPTVAGRWSLLPDREADGTVRAHALAR FT TLLDRHGVVTRGAVAAEGVEGGFSAVYRILAAFEESGQARRGYVVEGLGAAQFAMEGAV FT DRLRAVANARERGDGPAGPEDFPRDGSANRRGTVGSANGSGPEGSAPRPGTGGPAGPHD FT SPGPADDSSLDPLAPFDPQDPFGDIGAGRPSDDVFADPDGLGRSPSRGDYISPRDYAEP FT GAGGPRGGGGPRGGGAHGRSEGPRGGYDTGFPGRRDRASVGPRAVVLAAADPANAYGAA FT LGWPEPPAGATHKPGRKAGSLVVLVEGEPALYMERGGKTLLLWPSDPDRLPTEDPRLRA FT AAEALAEAARAGSLGTVTVERVNGTAALTSPFGPLLEGAGFIATPRGLRIRA" FT misc_feature 10934..10937 FT /note="end of real overlap with 9A10" FT misc_feature complement(11042..11296) FT /note="Pfam match to entry helicase_C PF00271, Helicases FT conserved C-terminal domain, score 42.17" FT misc_feature complement(11351..12235) FT /note="Pfam match to entry DEAD PF00270, DEAD and DEAH box FT helicases, score 30.04" FT misc_feature complement(12101..12124) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(12268..12271) FT /note="possible RBS upstream of SC7C7.16c" FT CDS 12456..13322 FT /transl_table=11 FT /gene="SCO5762" FT /gene_synonym="SC4H8.01" FT /gene_synonym="SC7C7.17" FT /product="putative AraC family transcriptional regulator" FT /note="SC4H8.01, unknown, partial CDS, len >29 aa" FT /note="SC7C7.17, possible araC family transcriptional FT regulatory protein, len: 288 aa; some similarity to members FT of the araC family e.g. ADA_SALTY ADA regulatory protein FT (352 aa), fasta scores; opt: 161 z-score: 197.6 E(): FT 0.0009, 31.0% identity in 129 aa overlap. Overlaps and FT extends CDS from neighboring cosmid SC4H8.01. Contains FT probable helix-turn-helix motif at aa 189-210 (Score 1161, FT +3.14 SD) and Pfam match to entry HTH_2 PF00165, Bacterial FT regulatory helix-turn-helix proteins, araC family, score FT 74.61" FT /db_xref="GOA:O50480" FT /db_xref="InterPro:IPR018060" FT /db_xref="UniProtKB/TrEMBL:O50480" FT /protein_id="CAA19863.1" FT /translation="MAGSGERARHWRYAELPDVDLLRARYIRKTFVRHTHEHFVIAAIA FT DGVEVFHHGGSDQYAGAGSLALVNPDTPHTGRAGVPEGWRYGAVYPAPGLVAEIAAETT FT TLRGTPGFVRPVLDDPYAVELVHRVLRAADDGNALAADTLLRVAVTRLLRLNGGPLPRR FT RVRTAGAGTAARARAVLEERMADPPSLERLAGELGSSPFALLRAFRDAYGMPPHTWLTD FT ARVRRARRLLDAGTSPAEAAVAVGFTDQPHLNRHFARIVGVPPGSYQRERKNVQDAPRE FT PLLPFEA" FT misc_feature 13014..13271 FT /note="Pfam match to entry HTH_2 PF00165, Bacterial FT regulatory helix-loop-helix proteins, araC family, score FT 74.61" FT RBS 13314..13317 FT /note="possible RBS upstream of SC4H8.02" FT CDS 13319..14089 FT /transl_table=11 FT /gene="SCO5763" FT /gene_synonym="SC4H8.02" FT /product="putative membrane protein SC4H8.02" FT /note="SC4H8.02, possible membrane protein, len: 256 aa. FT Contains possible hydrophobic membrane spanning region" FT /db_xref="InterPro:IPR011606" FT /db_xref="UniProtKB/TrEMBL:O50481" FT /protein_id="CAA15869.1" FT /translation="MTEQTALPDAPDTGGAGAKPDAAVVRDALGVGVAVGLSGFAFGVT FT SAGSGLTLAQTCALSLLVFTGASQFALVGALAAGGNPLTAAAGAFFLGVRNAFYGLRLS FT QLLALPRAVRPFAAQWVIDETTAVALAQPTRRGVRIGFTVTGLTLYVLWNLTTLLGALG FT AEAIGDTDAWGLDAAGPAVFLALLAPMLKNTTERAVAALAVLLGLGLLPVLPAGVPVLV FT AALAAPLVLWARGRRAGDTEDGAARGTAEGEGER" FT RBS 14074..14078 FT /note="possible RBS upstream of SC4H8.03" FT CDS 14086..14394 FT /transl_table=11 FT /gene="SCO5764" FT /gene_synonym="SC4H8.03" FT /product="putative membrane protein" FT /note="SC4H8.03, putative membrane protein, len: 102 aa. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="InterPro:IPR008407" FT /db_xref="UniProtKB/TrEMBL:O50482" FT /protein_id="CAA15870.1" FT /translation="MSVWIAIGVTAVGCYAVKLLGLLVPAGALERPLVRRLAALLPVAL FT LAALTAQQTFADGQRLVLDARAAGVAAAAVALLLRAPFLLVVAAAVVVTAGVRAMGG" FT CDS complement(14404..15429) FT /transl_table=11 FT /gene="SCO5765" FT /gene_synonym="SC4H8.04c" FT /product="hypothetical protein SC4H8.04c" FT /note="SC4H8.04c, unknown, len: 341 aa; first start site FT used" FT /db_xref="UniProtKB/TrEMBL:O50483" FT /protein_id="CAA15871.1" FT /translation="MAPEPGPPAGTAFRPTVCPMAETGASPLPAIPPPASPRAQGPRSP FT LARAEHFVWLTARVLEQRLFAHDFRGGDPGPVETALEAYRNDDGGYGHALEPDLRGPAS FT QPLHTAHALRVLDAVGRCGGQRAERVCRYLTAVSTPDGALPVTRADRDGAPAAPFLPVV FT ADPPGELLVTGPVVGLLHRNEVWHAWLFRATDFCWQAAESLGSPHPCEARAAVAFLDTA FT PDRPRARAAADRLGRLVREQRLAVLDPDDLDACPVPAGHTPGEHLFPHNYARDPRSLAR FT AWFTDDEMARSLDFLAAGQEDDGGWPVRRRRWAPVPALEARGRMTLEALRTLRAYGRPL FT G" FT RBS 15437..15441 FT /note="possible RBS upstream of SC4H8.05" FT CDS 15454..15648 FT /transl_table=11 FT /gene="SCO5766" FT /gene_synonym="SC4H8.05" FT /product="hypothetical protein SC4H8.05" FT /note="SC4H8.05, unknown, len: 64 aa; similar to M. FT tuberculosis hypothetical protein TR:E1173868 (MTV002.03c) FT (68 aa), fasta scores; opt: 193 z-score: 307.9 E(): FT 5.8e-10, 40.6% identity in 64 aa overlap. Note that this FT protein is also upstream of RecA" FT /db_xref="UniProtKB/TrEMBL:O50484" FT /protein_id="CAA15872.1" FT /translation="MRLTVFWERMTDHFGPGYADTFARDHVMTELGGRTVHEALDAGWD FT AKDVWRVVCTVMNVPREQR" FT CDS 15820..17028 FT /transl_table=11 FT /gene="SCO5767" FT /gene_synonym="SC4H8.06" FT /product="putative membrane protein" FT /note="SC4H8.06, unknown, probable integral membrane FT protein, len: 402 aa; weakly similar to several hypotheical FT proteins from B. subtilis and Methanococcus e.g. FT TR:E1184257 (EMBL:Z99120) from B. subtilis (369 aa), fasta FT scores; opt: 375 z-score: 321.7 E(): 1e-10, 24.1% identity FT in 348 aa overlap. C-terminal region highly similar to FT TR:Q54391 (EMBL:X76076) Streptomyces lividans RecA gene FT (fragment) 75 aa; fasta scores: opt: 490 Z-score: 548.1 FT E(): 6.7e-23; 96.000% identity in 75 aa overlap. Start site FT chosen by similarity. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="InterPro:IPR002549" FT /db_xref="UniProtKB/TrEMBL:O50485" FT /protein_id="CAA15873.1" FT /translation="MPRWLPRAMVLALALIAAFQLGSWAFHQLTGLLINVLIAFFLALA FT IEPAVSWMAGRGMRRGFATFLVFLAVLIAAAGFVTLLGSMLAGQIVKMVEEFPDYLDSV FT INWVNGHFHTELRRVDIQEGLLRSDWLRNYVQNSATGVLDVSAQVLGGLFQLLTVLLFS FT FYFAADGPRLRRGLCSVLPPARQAEVLRAWEIAVDKTGGYLYSRGLMALVSGVAHYILL FT EILEVPYAPALAVWVGLVSQFIPTIGTYLAGALPMLIAFTVNPWYALWVLVFVVIYQQF FT ENYVLQPKLTSKTVDIHPAVAFGSVIAGTALLGAVGALIAIPAVATLQAFLGAYVKRYD FT VTDDPRVHGRRGRRSVSGTSTRLRKLWTRRPEPGLEGPERTEGPERTEGGEGTDGTRDG FT GSS" FT misc_feature 16801..18879 FT /note="99% match to EM_BA:SLRECA X76076 S.lividans RecA FT gene from: 1 to: 2085" FT CDS complement(17165..17365) FT /transl_table=11 FT /gene="SCO5768" FT /gene_synonym="SC4H8.07c" FT /product="hypothetical protein SC4H8.07c" FT /note="SC4H8.07c, unknown, len: 66 aa; similar to M. FT tuberculosis hypothetical protein TR:O06782 (EMBL:Z95972) FT MTCI376.19 (51 aa), fasta scores; opt: 107 z-score: 185.7 FT E(): 0.0038, 38.6% identity in 44 aa overlap" FT /db_xref="UniProtKB/TrEMBL:O50486" FT /protein_id="CAA15874.1" FT /translation="MARITIDLDAELVVEVMVLAGIGSPQDAVEAVVRDYIARGHRTET FT RTEFKDRNLREIDAKPQEPQG" FT RBS complement(17374..17377) FT /note="possible RBS upstream of SC4H8.07c" FT RBS 17644..17648 FT /note="possible RBS upstream of recA" FT CDS 17654..18778 FT /transl_table=11 FT /gene="SCO5769" FT /gene_synonym="recA" FT /product="recombinase A" FT /note="SC4H8.08, recA, recombinase A, len: 374 aa; highly FT similar to many e.g. SW:RECA_STRLI (EMBL:X76076) FT recombinase A protein (RecA) from Streptomyces lividans FT (374 aa), fasta scores; opt: 2372 z-score: 3058.5 E(): 0, FT 99.7% identity in 374 aa overlap. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop) and PS00321 recA FT signature" FT /db_xref="GOA:O50487" FT /db_xref="HSSP:1MO3" FT /db_xref="InterPro:IPR001553" FT /db_xref="UniProtKB/Swiss-Prot:O50487" FT /protein_id="CAA15875.1" FT /translation="MAGTDREKALDAALAQIERQFGKGAVMRMGDRTNEPIEVIPTGST FT ALDVALGVGGIPRGRVVEVYGPESSGKTTLTLHAVANAQKAGGQVAFVDAEHALDPEYA FT KKLGVDIDNLILSQPDNGEQALEIVDMLVRSGALDLIVIDSVAALVPRAEIEGEMGDSH FT VGLQARLMSQALRKITSALNQSKTTAIFINQLREKIGVMFGSPETTTGGRALKFYASVR FT LDIRRIETLKDGTDAVGNRTRVKVVKNKVAPPFKQAEFDILYGQGISREGGLIDMGVEN FT GFVRKAGAWYTYEGDQLGQGKENARNFLKDNPDLANEIEKKIKQKLGVGVHPEESATEP FT GADAASAAPADAAPAVPAPTTAKATKSKATAAKS" FT misc_feature 17849..17872 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 18293..18319 FT /note="PS00321 recA signature" FT RBS 18985..18988 FT /note="possible RBS upstream of recX" FT CDS 18998..19564 FT /transl_table=11 FT /gene="SCO5770" FT /gene_synonym="SC4H8.09" FT /gene_synonym="recX" FT /product="RecX, putative regulatory protein" FT /note="SC4H8.09, recX, len: 188 aa; similar to FT mycobacterial RecX proteins e.g. TR:E1173865 FT (EMBL:AL008967) MTV002.01c (174 aa), fasta scores; opt: 371 FT z-score: 436.7 E(): 3.9e-17, 42.7% identity in 164 aa FT overlap" FT /db_xref="GOA:O50488" FT /db_xref="InterPro:IPR003783" FT /db_xref="UniProtKB/Swiss-Prot:O50488" FT /protein_id="CAA15876.1" FT /translation="MEPSAEDGGATSSSRAEKGEPPRDPVEQARAICLRLLTGTPRTRR FT QLAEALRKREIPEEAAEEVLSRFEEVGLINDGAFAQAWVESRHHGRGLARRALARELRT FT KGVEAALIDVAVSQLDTEQEEETARDLVARKLRATRGLDRDKRLRRLAGMLARKGYSEG FT MALRVVRQALEEEGEDTEHLGDEGF" FT CDS complement(19921..20319) FT /transl_table=11 FT /gene="SCO5771" FT /gene_synonym="SC4H8.10c" FT /product="conserved hypothetical protein" FT /note="SC4H8.10c, hypothetical protein, len: 132 aa; FT similar to TR:AAK45350 (EMBL:AE006990) Mycobacterium FT tuberculosis CDC1551 conserved hypothetical protein MT1096, FT 131 aa; fasta scores: opt: 429 Z-score: 543.2 E(): 1.3e-22; FT 57.143% identity in 119 aa overlap" FT /db_xref="InterPro:IPR001763" FT /db_xref="UniProtKB/TrEMBL:O50489" FT /protein_id="CAA15877.1" FT /translation="MSGPTGIDALLERVRAGYRRIAPDEAYDAAEAGTALLVDIRYAAL FT RERDGVIPGALVIERNELEWRLDPLGSHRVPEATDHDVRVVVVCDEGYASSLAAESLHR FT LGLHRATDLIGGFQAWRTAGLPVAARDQ" FT CDS complement(20316..20864) FT /transl_table=11 FT /gene="SCO5772" FT /gene_synonym="SC4H8.11c" FT /product="hypothetical protein SC4H8.11c" FT /note="SC4H8.11c, unknown, len: 182 aa" FT /db_xref="GOA:O50490" FT /db_xref="InterPro:IPR010300" FT /db_xref="UniProtKB/TrEMBL:O50490" FT /protein_id="CAA15878.1" FT /translation="MSLPSVSPASPVSASASTPAPTQAQLLDFVRRAAADAQLVASLPL FT DPEGRTWMRLAGPGGSEAWLIGWPPGTGTGWHDHADSVGAFVTAAGELKENALAARLPT FT DGWKTLELSDGVDRERRLSVGTGRAFGRHHVHEVLNESSDRHAVSVHAYYPPLPQIRRY FT SRSGQTLRLEQVERPQDWQ" FT RBS complement(20326..20329) FT /note="possible RBS upstream of SC4H8.10c" FT RBS complement(20873..20876) FT /note="possible RBS upstream of SC4H8.11c" FT CDS complement(21159..22784) FT /transl_table=11 FT /gene="SCO5773" FT /gene_synonym="SC4H8.12c" FT /product="possible monooxygenase" FT /note="SC4H8.12c, possible monooxygenase, len: 541 aa; FT weakly similar to many eg. TR:Q54171 (EMBL:X87093) putative FT oxygenase urdE from Streptomyces fradiae (495 aa), fasta FT scores; opt: 333 z-score: 428.9 E(): 1.1e-16, 30.4% FT identity in 539 aa overlap" FT /db_xref="GOA:O50491" FT /db_xref="InterPro:IPR003042" FT /db_xref="UniProtKB/TrEMBL:O50491" FT /protein_id="CAA15879.1" FT /translation="MDPVIITGAGPVGLTLALALARQEVPCVVLDEGPGKDEPRPARTV FT VLREEAVALVERLTGTPLTGLGSRWAGWRSMRRKQVTREVVFGDADPAPLHIAQHELAG FT VLRTALARERLVKIAVDSRLDGIEQEKSGVTAHTRGPAGTWWRGSYLVGCDGPRSTVRK FT LQDIRFPGRTAVERYAVAALRTELPWTDEALLHRMPPWRTTGPSAGEVVGRPLPDGVWR FT LDWLLPPGKDLVTPELLVNRVRETLTGWAADGSTPAYELLDTGVHTVHHRLARRWRVGR FT VLLAGDAAHLLGALGTQGLEEGLLDADNLAWKLALAWHHGPREALLDSYQQERRAAISA FT RLRAADQLLPLVRGGGGLRAYVPGSARGNDALLTDGHLGRGTLGAQGTYADSPLAPEDL FT GGEVSVGTPPGTPVTDVRVTAEDGTFVRLRDRLGRGALLVVLIAPGTGVWDRKHWVTAG FT IMPRLAAAVTALPHHAELLVAESYPGAAAHTVLLVRPDGHLVTALNGVRPADLYAAAES FT ALGGAAARAATEAAEGAGAAAGSR" FT RBS complement(22794..22799) FT /note="possible RBS upstream of SC4H8.12c" FT CDS complement(22961..23860) FT /transl_table=11 FT /gene="SCO5774" FT /gene_synonym="gluD" FT /product="glutamate permease" FT /note="SC4H8.13c, gluD, probable glutamate permease, len: FT 299; similar to many members of the HisMQ subfamily of the FT binding-protein dependent transporters eg. GLUD_CORGL FT P48245 glutamate transport system permease protein from FT Corynebacterium glutamicum (273 aa), fasta scores; opt: 673 FT z-score: 843.4 E(): 0, 47.0% identity in 251 aa overlap. FT Contains PS00402 Binding-protein-dependent transport FT systems inner membrane component signature" FT /db_xref="GOA:O50492" FT /db_xref="InterPro:IPR010065" FT /db_xref="UniProtKB/TrEMBL:O50492" FT /protein_id="CAA15880.1" FT /translation="MSSVLYDAQGPRAKRRNVVFTAVFVVVVLALLWWVYATLDEKGQL FT EWAKWQMFFTSDEPWSTYIWPGLQNTLKAAALSMVIALPLGAVLGIARLSDHAWVRIPV FT AIVVEFFRSIPVLVLMIFGLALFAEYTDVSSDDRPLYAVVTGLVLYNASVLAEIVRAGI FT LALPKGQAEGAMAIGLRKGQSMRLILLPQAVTTMLPAIVSQLVVILKDTALGGAVLTFP FT ELLASANTMSGYYGANVIASFTVVAVIYIALNFSLTTFASWLERRLRRAKKSTGAVLKA FT DDAGIPGGAATGAGGGGN" FT misc_feature complement(23288..23374) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp signature" FT CDS complement(23857..24525) FT /transl_table=11 FT /gene="SCO5775" FT /gene_synonym="gluC" FT /product="glutamate permease" FT /note="SC4H8.14c, gluC, probable glutamate permease, len: FT 222; similar to many members of the HisMQ subfamily of the FT binding-protein dependent transporters eg. GLUC_CORGL FT P48244 glutamate transport system permease protein from FT Corynebacterium glutamicum (225 aa), fasta scores; opt: 730 FT z-score: 1209.4 E(): 0, 58.8% identity in 199 aa overlap. FT Contains PS00402 Binding-protein-dependent transport FT systems inner membrane component signature" FT /db_xref="GOA:O50493" FT /db_xref="InterPro:IPR010065" FT /db_xref="UniProtKB/TrEMBL:O50493" FT /protein_id="CAA15881.1" FT /translation="MFDFLQDYDLLGAFWTTVQLAALSAVGSLIWGTILAAMRVGPVPL FT MRGLGAAYVNTVRNIPLTVIILFASLGLNQTLGVTLGGGDSFETINFRLAVLGLVLYTS FT AFVCEALRSGINTVPVGQAEAARAIGLSFGQVLRLVVLPQAFRSTVGPLANVLIALIKN FT TTVAAAIGVAEAAALMKDMIENEAQLLLISAIIAVGFVILTLPTGLILGWVGKKVAVKR FT " FT RBS complement(23871..23877) FT /note="possible RBS upstream of gluD" FT misc_feature complement(24097..24183) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane component signature" FT RBS complement(24529..24532) FT /note="possible RBS upstream of gluC" FT CDS complement(24610..25446) FT /transl_table=11 FT /gene="SCO5776" FT /gene_synonym="gluB" FT /product="glutamate binding protein" FT /note="SC4H8.15c, gluB, probable glutamate binding protein, FT len: 278 aa; similar to many members of the periplasmic FT solute-binding family 3 eg. GLUB_CORGL P48242 FT glutamate-binding protein precursor from Corynebacterium FT glutamicum (295 aa), fasta scores; opt: 733 z-score: 768.3 FT E(): 0, 46.9% identity in 277 aa overlap. Contains FT N-terminal signal sequence and appropriately positioned FT PS00013 Prokaryotic membrane lipoprotein lipid attachment FT site; also contains PS01039 Bacterial extracellular FT solute-binding proteins, family 3 signature" FT /db_xref="GOA:O50494" FT /db_xref="HSSP:1GGG" FT /db_xref="InterPro:IPR001638" FT /db_xref="UniProtKB/TrEMBL:O50494" FT /protein_id="CAA15882.1" FT /translation="MKLRKVSAASAAVLALALTATACGGDDKDSGSSDGGGKKITIGIK FT FDQPGLGQKTPDGYAGFDVDVATYVAKKLGYTEDQIEWKESKSADRETMLQRGDVDFIA FT ATYSITPERSEKVDFAGPYLLAHQDVLIRADDDKIKSPEDLNDAKLCSVTGSTSAQNVK FT DKLAPKAQLQKYPTYSACLNGLQTGAIDALTTDDSILAGYAAQSQFKGKFKLGGFKMTN FT ENYGIGVKKGSDLKAKINDALEAMATDGAWDKAVKDNFGPANYKNEPAPKIGDIKS" FT misc_feature complement(25225..25266) FT /note="PS01039 Bacterial extracellular solute-binding FT proteins, family 3 signature" FT misc_feature complement(25378..25410) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS complement(25455..25459) FT /note="possible RBS upstream of gluB" FT CDS complement(25572..26348) FT /transl_table=11 FT /gene="SCO5777" FT /gene_synonym="gluA" FT /product="glutamate uptake system ATP-binding protein" FT /note="SC4H8.16c, gluA, probable glutamate uptake system FT ATP-binding protein, len: 258 aa; highly similar to many FT amino-acid uptake ATP-binding proteins eg. GLUA_CORGL FT P48243 glutamate transport atp-binding protein from FT Corynebacterium gluamicum (242 aa), fasta scores; opt: 1152 FT z-score: 1564.5 E(): 0, 71.5% identity in 242 aa overlap. FT Contains PS00017 ATP/GTP-binding site motif A (P-loop) and FT PS00211 ABC transporters family signature" FT /db_xref="GOA:O50495" FT /db_xref="HSSP:1B0U" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:O50495" FT /protein_id="CAA15883.1" FT /translation="MTEVSVAKEDKAATGELVVLKSVNKHFGALHVLQDIDLTIQRGEV FT VVVIGPSGSGKSTLCRTINRLETVDDGSITIDGKPLPAEGKELARLRADVGMVFQSFNL FT FAHKTVLENVTLGQVKVRKVDAKKAEEKARALLDRVGVGAQADKYPAQLSGGQQQRVAI FT ARALAMDPKVMLFDEPTSALDPEMINEVLEVMKQLAEDGMTMIVVTHEMGFARSAANRV FT VFMADGRIVEEATPDQFFSNPRSDRAKDFLSKILHH" FT misc_feature complement(25848..25892) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(26178..26201) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(26359..26362) FT /note="possible RBS upstream of gluA" FT RBS 26642..26645 FT /note="possible RBS upstream of SC4H8.17c" FT CDS 26651..27337 FT /transl_table=11 FT /gene="SCO5778" FT /gene_synonym="SC4H8.17" FT /product="two-component system regulator" FT /note="SC4H8.17, two-component system transcriptional FT regulator, len: 228 aa; similar to many eg. VANR_ENTFA FT Q47744 regulatory protein VanR from enterococcuus faecalis FT (220 aa), fasta scores; opt: 469 z-score: 742.2 E(): 0, FT 37.1% identity in 224 aa overlap" FT /db_xref="GOA:O50496" FT /db_xref="HSSP:1B00" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:O50496" FT /protein_id="CAA15884.1" FT /translation="MRLLLVEDDNHVAAALSAILARHGFDVTHARSGEEALQALVPEVD FT GFGVVLLDLGLPDQDGYEVCGKIRKRTSTPVIMVTARADVRSRIHGLNLGADDYVVKPY FT DTGELLARIHAVSRRTAHEDATGSTETVVRLGAVRIELPTRQVSVDGSVVQLTRKEFDL FT LALLAQRPGVVFRREQIISEVWRTSWEGTGRTLEVHVASLRSKLHMPALIETVRGVGYR FT LVAPTA" FT CDS 27347..28792 FT /transl_table=11 FT /gene="SCO5779" FT /gene_synonym="SC4H8.18" FT /product="two-component system sensor" FT /note="SC4H8.18, two-component system sensor/histidine FT kinase, partial CDS, len: >481 aa; similar to many e.g. FT COPS_PSESM Q02541 sensor protein CopS from Pseudomonas FT syringae (487 aa), fasta scores; opt: 324 z-score: 387.1 FT E(): 2.3e-14, 24.8% identity in 456 aa overlap. Contains FT possible hydrophobic membrane spanning regions" FT /db_xref="GOA:Q8CJQ5" FT /db_xref="InterPro:IPR003660" FT /db_xref="UniProtKB/TrEMBL:Q8CJQ5" FT /protein_id="CAD55234.1" FT /translation="MSTRLLPLLIVLMAAVLLALGVPLGVSVARAEQQKVVIDRIDDTA FT RFASLAQFVTEDGSGGSRRTDTDERLETLQTELTSYYEVYGIKAGVFYRNHIPMANAPT FT TWFLPQAGEVRDSFDEALLSRRSHDPAQVWPWQDGTLVVASPVIRDGDVVAVVVTESPT FT DSMRSSTLRGWLVIGAGEVAAMLLAVGAALRLTGWVLRPVRVLDATTHDIATGRLKSRV FT APSGGPPELRRLARSFNEMADHVEDVLEQQRAFVADASHQLRNPLAALLLRIELLALEL FT PEGNEEIASVQTEGKRLARVLDDLLDLALAEHSQADLKVTDVGALAAERVAAWSPTADV FT KGVRLVGDCPPTTGWADPVALSSALDAVIDNAVKFTPHGESVRVEVASTGDAATVVVTD FT NGPGLTDEELTRVGDRFWRSGRHQNINGSGLGLSICRALLAAGNGSISFGHHEPHGLRV FT TVTVPRTGTVPKEPERVYGLTDR" FT misc_feature complement(28681..28791) FT /note="overlap with Cosmid St4H2" FT misc_feature 28681..28791 FT /note="overlap with Cosmid SC4H8 from: 15450 to: 15560" FT CDS complement(28771..29766) FT /transl_table=11 FT /gene="SCO5780" FT /gene_synonym="SC4H2.01c" FT /product="putative secreted protein" FT /note="SC4H2.01c, probable secreted protein, len: 331 aa; FT some similarity to a secreted protein from Brucella abortus FT BCSP_BRUAB P12920 31 kd immunogenic protein precursor (329 FT aa), fasta scores; opt: 399 z-score: 357.4 E(): 1.1e-12, FT 32.7% identity in 336 aa overlap. Contains probable FT N-terminal signal sequence" FT /db_xref="InterPro:IPR011852" FT /db_xref="UniProtKB/TrEMBL:O69956" FT /protein_id="CAA18317.1" FT /translation="MSTLLSRIGRRRAVQGTVAGAVVLGLLLWWLLPLGEKPPSGTITF FT STGTRAGVYQKYGELLRTELRKDMPGLDVRLMTSAGSQENVERVASGEADFTIAAADAV FT ETYKLAGSPGAEGLRGVTRLYDDYVQLVVPSDSDIQSVRDLRGKRVAIGLPNSGVRLIA FT TRLLKAVGIDPETDITPRADGIDTGPGRLGDELDAFFWSGGVPTDGLKEIAESSAFRFV FT PIGDDLVTKLHRSGGATRYYRTTNMPESAYPTVQNGAVVPTMAVSNLLVTRADVDPRLT FT EWLTRTVLDSRDGIGAHVHSAQLVDLRTAIYTDPLELHEGARRYYRSVKP" FT RBS complement(29775..29778) FT /note="possible RBS upstream of SC4H2.01c" FT CDS 29816..30355 FT /transl_table=11 FT /gene="SCO5781" FT /gene_synonym="SC4H2.02" FT /product="putative secreted protein" FT /note="SC4H2.02, putative secreted protein, len: 179 aa; FT Proline-rich in N-terminus. Contains possible N-terminal FT region signal peptide sequence" FT /db_xref="InterPro:IPR019229" FT /db_xref="UniProtKB/TrEMBL:O69957" FT /protein_id="CAA18318.1" FT /translation="MAVATVVGMSSTPPAESGPPSAEGRTPPDQGRTSPDQGRTSPADL FT VRAFHLAFGLDARSTPTEVPPALAAHRGELLAEEAAEVAEVSVRGPLDRLAHELADVVY FT VAYGTALVHGIDLDAVIAEVHRSNMTKLGPDGRVSRRADGKVLKGDHYEIPDVSGVLRR FT QGWTPRTPDAPEPAGA" FT CDS complement(30451..31686) FT /transl_table=11 FT /gene="SCO5782" FT /gene_synonym="SC4H2.03c" FT /product="putative transmembrane transport protein" FT /note="SC4H2.03c, possible transmembrane transport protein, FT len: 411 aa; similar to several hypothetical proteins e.g. FT M. tuberculosis TR:O05881 (EMBL:Z95121) MTCY20B11.11C (385 FT aa), fasta scores opt: 1226 z-score: 1612.0 E(): 0, 53.5% FT identity in 372 aa overlap, and to members of the KEFB/KEFC FT potassium transporters family e.g. KEFB_ECOLI P45522 FT glutathione-regulated potassium-efflux protein (601 aa), FT fastascores; opt: 327 z-score: 292.9 E(): 4.3e-09, 25.3% FT identity in 396 aa overlap" FT /db_xref="GOA:O69958" FT /db_xref="InterPro:IPR006153" FT /db_xref="UniProtKB/TrEMBL:O69958" FT /protein_id="CAA18319.1" FT /translation="MHSAVLLIEFGSIILGLGLLGRFAGRYRLSPIPLYLLAGLAFGEG FT GLLPLGASEEFVATGAEIGVILLLLMLGLEYTASDLVTNLKSHYPAGLVDCALNAVPGA FT VAALLMGWGPVAAVVLAGVTWISSSGVIAKVLGDLGRVGNRETPVILSVLVLEDLAMAV FT YLPIVTALVAGAGLMTGSITLAVALAAAGLVLFVAVRYGRLISRFVSSDDPEKLLLVVL FT GLTILVAGVAQQLQVSAAVGAFLVGIALSGEVAEGAHTLLSPLRDLFAAVFFVFFGLHT FT DPASIPPVLLPALALALLTAVTKIATGYWAARRAGISVKGRWRAGGALVARGEFSIVIA FT GLAVSAGIEPSLGPLATAYVLILVVLGPLTARFTEPLAMRLFPRRDNPDRPSGLAEGTP FT RAAATEEASVGD" FT CDS complement(31691..32176) FT /transl_table=11 FT /gene="SCO5783" FT /gene_synonym="SC4H2.04c" FT /product="conserved hypothetical protein SC4H2.04c" FT /note="SC4H2.04c, hypothetical protein, len: 161 aa; FT similar to hypothetical proteins from several organisms FT e.g. M. tuberculosis TR:O05882 (EMBL:Z95121) MTCY20B11.12C FT (160 aa), fasta scores; opt: 315 z-score: 557.4 E(): 8e-24, FT 40.0% identity in 150 aa overlap (also upstream of a FT putative transport protein)" FT /db_xref="GOA:O69959" FT /db_xref="InterPro:IPR006037" FT /db_xref="UniProtKB/TrEMBL:O69959" FT /protein_id="CAA18320.1" FT /translation="MSAPRLRATPLPGIGVQYDLVTREHRHLSVVAHRDGARTVNVYRS FT DDPDSCAHSLRLTGPEAGALIDALKPSHHSASLLYTTDLGLVAERIEVAATSRWNGRLL FT GDTRLRTDTGASIVAVLRRAEAIPSPAPDFRLVGGDTLIVIGTREGVDAAAAILGQE" FT RBS complement(31694..31698) FT /note="possible RBS upstream of SC4H2.03c" FT RBS complement(32186..32189) FT /note="possible RBS upstream of SC4H2.04c" FT RBS 32282..32286 FT /note="possible RBS upstream of SC4H2.05" FT CDS 32291..33367 FT /transl_table=11 FT /gene="SCO5784" FT /gene_synonym="SC4H2.05" FT /product="putative two-component sensor" FT /note="SC4H2.05, probable two-component sensor protein, FT len: 358 aa; similar to many e.g. DEGS_BACSU P13799 sensor FT protein DegS (ec 2.7.3.-), Bacillus subtilis (385 aa), FT fasta scores; opt: 317 z-score: 334.6 E(): 2e-11, 31.3% FT identity in 227 aa overlap. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:O69960" FT /db_xref="InterPro:IPR003660" FT /db_xref="UniProtKB/TrEMBL:O69960" FT /protein_id="CAA18321.1" FT /translation="MGVVTDIRSRSRSAKLAAGVSCEKAGRSGKRNVSLFWRIFSLNAA FT GLVVATALLLGPVTVSTPVLAGEALVLLAGLAALLAGNAVVLRIGLTPLHRLGRAMSTA FT DLLVPGTRPEVSGPAEAAQLIATYNTMLDRLQAERAAGAGRALQAQERERHRIARELHD FT EVGQTLTAVLLQLKRVADRVPGELRDEVTLAQEATRAGLDEIRRIARRLRPGVLEELGL FT ASALRSLAAEFTHHGLTVQHHIPGDLPPLAPEAELVLYRVAQEGLTNTARHADAARAAL FT TLHPLPGDAGVELLVRDDGTGLGTAAEGAGIRGMRERALLIGAEIHFEPAPGGGTDVRL FT RVPAPPGDRCADRTGDSP" FT CDS 33367..34026 FT /transl_table=11 FT /gene="SCO5785" FT /gene_synonym="SC4H2.06" FT /product="putative two-component regulator" FT /note="SC4H2.06, probable two-component transcriptional FT regulator, len: 219 aa; similar to many e.g. DEGU_BACSU FT P13800 transcriptional regulatory protein DegU (229 aa), FT fasta scores; opt: 343 z-score: 736.1 E(): 0, 37.1% FT identity in 224 aa overlap. Contains PS00622 Bacterial FT regulatory proteins, luxR family signature, Pfam match to FT entry response_reg PF00072, Response regulator receiver FT domain, score 147.25 and Pfam match to entry GerE PF00196, FT Bacterial regulatory proteins, luxR family, score 99.11" FT /db_xref="GOA:O69961" FT /db_xref="HSSP:1FSE" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:O69961" FT /protein_id="CAA18322.1" FT /translation="MSARPPIRVLLADDHTLVRRGVRLILDGEPDLTVVAEAGDGAEAV FT AAARATEIDLAVLDVAMPRMTGLQAARELSRRLPELRILILTMYDNEQYFFEALKAGAC FT GYVLKSVADRDLVEACRAAVRDEPFIYPGAERALVRSYLDRVQGGGGLPERPITEREEE FT ILKLVAEGHTSKEIGELLFISAKTVERHRANLLQKLGVRDRLELTRYAIRAGLIEP" FT misc_feature 33385..33726 FT /note="Pfam match to entry response_reg PF00072, Response FT regulator receiver domain, score 147.25" FT misc_feature 33826..34023 FT /note="Pfam match to entry GerE PF00196, Bacterial FT regulatory proteins, luxR family, score 99.11" FT misc_feature 33877..33960 FT /note="PS00622 Bacterial regulatory proteins, luxR family FT signature" FT CDS complement(34081..35283) FT /transl_table=11 FT /gene="SCO5786" FT /gene_synonym="SC4H2.07c" FT /product="putative secreted hydrolase" FT /note="SC4H2.07c, possible secreted hydrolase, len: 400 aa; FT similar in N-terminus to many e.g GUNA_STRLI P27035 FT endoglucanase CelA precursor (459 aa), fasta scores; opt: FT 376 z-score: 257.5 E(): 4e-07, 37.7% identity in 175 aa FT overlap. Contains a very Thr- Pro-rich region at aa FT 143-170, a possible N-terminal signal sequence and an FT appropriately positioned PS00013 Prokaryotic membrane FT lipoprotein lipid attachment site. C-terminal region has no FT apparent similarities. Also contains a TTA leucine codon; a FT potential target for action of bldA" FT /db_xref="GOA:O69962" FT /db_xref="HSSP:1EXG" FT /db_xref="InterPro:IPR012291" FT /db_xref="UniProtKB/TrEMBL:O69962" FT /protein_id="CAA18323.1" FT /translation="MRTRVLRLLRRPWTAAVAAVALVVSVLVAMPASGAAAAACRVDYG FT VDAWAGGYTARVRITNLGPAVSDWRLTWTYTGDQQVTSAWNATVTQTGASVVAVDAGWN FT GAVSTGGTAEFGLQGTWRSADPAPDDFALNGTSCGDGGTPTATPTTSPTAPPTTPPTTP FT PPTTPPPAAECGDAVICSGFEDQAGPEPSGDWRFTAPDCQGTGTAAVDSAVSHAGGRSL FT RVDGRAGYCNHAFVAHTADLSSVGPVMYVRMWVRHTTALPTSHVTFVSMPDSAQGGRAL FT RVGGQNGALQWNRESDDATLPAQSPAGVALSRPLPTDGWQCLRFAIDTSAAGLDTWLGD FT EQVPGLHADGVPTQDVDQQWLTRGTAPRPTALRLGWESYATGDDTVWFDDVAVGSAPIG FT C" FT misc_feature complement(35164..35196) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature complement(35260..35262) FT /note="TTA leucine codon; potential target for action of FT bldA" FT RBS complement(35290..35295) FT /note="possible RBS upstream of SC4H2.07c" FT CDS 35453..36970 FT /transl_table=11 FT /gene="SCO5787" FT /gene_synonym="SC4H2.08" FT /product="conserved hypothetical protein SC4H2.08" FT /note="SC4H2.08, unknown, len: 505 aa; highly similar to FT hypothetical proteins from many organisms e.g. YLEA_ECOLI FT P77645 hypothetical 53.7 kd protein in cute- (474 aa), FT fatsa scores; opt: 1101 z-score: 1288.4 E(): 0, 40.9% FT identity in445 aa overlap. Contains PS01278 Uncharacterized FT protein family UPF0004 signature" FT /db_xref="GOA:O69963" FT /db_xref="InterPro:IPR013848" FT /db_xref="UniProtKB/Swiss-Prot:O69963" FT /protein_id="CAA18324.1" FT /translation="MSSIDRSQSAGGTRTYEVRTYGCQMNVHDSERLSGLLEDAGYVRA FT PEGADGDADVVVFNTCAVRENADNKLYGNLGHLAPKKASRPGMQIAVGGCLAQKDRDTI FT VKRAPWVDVVFGTHNIGKLPVLLERARVQEEAQVEIAESLEAFPSTLPTRRESAYAAWV FT SISVGCNNTCTFCIVPALRGKEKDRRPGDILAEVEALVAEGVSEITLLGQNVNAYGSDI FT GDREAFSKLLRACGNIDGLERVRFTSPHPRDFTDDVIAAMAETPNAMPQLHMPLQSGSD FT PVLKAMRRSYRQERYLGIIEKVRAAIPHAAITTDIIVGFPGETEEDFEQTLHVVREARF FT AQAFTFQYSKRPGTPAAEMENQIPKAVVQERYERLVALQEEISWDENKKQVGRTLELMV FT AEGEGRKDGATHRLSGRAPDNRLVHFTKPDQEVRPGDVVTVEITYAAPHHLLAEGAVLD FT VRRTRAGDAWEKRNTAEQAKPAGVLLGLPKIGVPEPQPVVASGCGCD" FT misc_feature 35939..36001 FT /note="PS01278 Uncharacterized protein family UPF0004 FT signature" FT CDS 37020..37733 FT /transl_table=11 FT /gene="SCO5788" FT /gene_synonym="SC4H2.09" FT /product="hypothetical protein SC4H2.09" FT /note="SC4H2.09, unknown, len: 237 aa; similar to a FT hypothetical protein from Mycobacterium tuberculosis and M. FT leprae, TTR:O33233 (EMBL:Z98209) MTCY154.08C (231 aa), FT fasta scores; opt: 306 z-score: 320.4 E(): 1.3e-10, 33.2% FT identity in 241 aa overlap" FT /db_xref="UniProtKB/TrEMBL:O69964" FT /protein_id="CAA18325.1" FT /translation="MLVAAAVCPCPPLLVPEVAAGAAPELDAARAACTDALGVLAASRP FT DRLVVVGPADSAGPEVYPRDARGSFRGFGVDVEVYLGADSGGAGGAELPHGLAVGAWLL FT ARTGWTDVPVDVIGVGEELSAERCAAVGRDVAARAGRTALLVLGDASACRTLKAPGYLD FT ERAAPFDAEVGRALETADPAALAALDPGLARELKASGRAPWQVLAGAAGDSGLGGALLY FT EDAPYGVGYIVATWS" FT stem_loop 37800..37865 FT /note="hairpin loop with 26/32 bp stem" FT CDS complement(37868..38161) FT /transl_table=11 FT /gene="SCO5789" FT /gene_synonym="SC4H2.10c" FT /product="hypothetical protein SC4H2.10c" FT /note="SC4H2.10c, unknown, len: 97 aa" FT /db_xref="UniProtKB/TrEMBL:O69965" FT /protein_id="CAA18326.1" FT /translation="MGLLDNLKARLEPAKGKVSDLAQQHGDKIDRGLDKMARTVDERTK FT GKYSDRIQTGTGKAKGAMDRLAHKDDGGGEEGGAAPGGTPGGPPPAGPPPAS" FT RBS complement(38173..38176) FT /note="possible RBS upstream of SC4H2.11c" FT CDS complement(38186..38473) FT /transl_table=11 FT /gene="SCO5790" FT /gene_synonym="SC4H2.11c" FT /product="hypothetical protein SC4H2.11c" FT /note="SC4H2.11c, unknown, len: 95 aa" FT /db_xref="UniProtKB/TrEMBL:O69966" FT /protein_id="CAA18327.1" FT /translation="MGVFTRLFRRSKKTEAASGAETRTDVPDTGSAAEAKAAEAAGAAE FT PADAGPRNTAEAGEADGTSAEAGDPESVGIPKQQSAGEAVDNEADKGART" FT RBS complement(38479..38482) FT /note="possible RBS upstream of SC4H2.11c" FT CDS 38656..39594 FT /transl_table=11 FT /gene="SCO5791" FT /gene_synonym="SC4H2.12" FT /gene_synonym="miaA" FT /product="putative tRNA delta(2)-isopentenylpyrophosphate FT transferase" FT /note="SC4H2.12, miaA, probable tRNA FT delta(2)-isopentenylpyrophosphate transferase, len: 312 aa; FT similar to many e.g. SW:MIAA_ECOLI (EMBL:P16384) FT Escherichia coli tRNA delta(2)-isopentenylpyrophosphate FT transferase (EC 2.5.1.8) (316 aa), fasta scores; opt: 627 FT z-score: 781.4 E(): 0, 39.9% identity in 286 aa overlap. FT Contains PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:O69967" FT /db_xref="InterPro:IPR018022" FT /db_xref="UniProtKB/Swiss-Prot:O69967" FT /protein_id="CAA18328.1" FT /translation="MSSAPPAPRVIAVVGPTAAGKSDLGVFLAQRLGGEVVNADSMQLY FT RGMDIGTAKLTPEERGGVPHHLLDIWDVTVTASVAEYQRLARERIDALLAEGRWPILVG FT GSGLYVRGAVDNLEFPGTDPGIRARLEEELELRGPGALHARLAVADPEAARAILPSNGR FT RIVRALEVIEITGRPFTANLPGHDSVYDTVQIGVDVARPELHERIALRVDRMWEAGLVD FT EVRALEAQGLREGRTASRALGYQQVLAALAGECTLDEARAETVRATKRFARRQDSWFRR FT DPRVHWLSGGVADRTELPRLALSLVERPVTA" FT misc_feature 38698..38721 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 39687..39691 FT /note="possible RBS upstream of SC4H2.13" FT CDS 39696..40199 FT /transl_table=11 FT /gene="SCO5792" FT /gene_synonym="SC4H2.13" FT /product="putative transmembrane protein" FT /note="SC4H2.13, probable transmembrane protein, len: 167 FT aa; contains three possible transmembrane domains in FT C-terminus" FT /db_xref="GOA:O69968" FT /db_xref="UniProtKB/TrEMBL:O69968" FT /protein_id="CAA18329.1" FT /translation="MAMEAGPRDTAPSTEHGTADHGGPEPDGGALSPDGPDETPDGVAD FT GPAPAEMYGAEVEVELRPQRRLRIWQLAPIVCLAALGSLMFAFPLAFDFGDSGAVIAML FT GLLICSCAAGWGMMAARRVGYTWPGLPQRGSGRRADWRTILVYALAVAAVVVLAVWRVA FT RLRG" FT RBS 40267..40270 FT /note="possible RBS upstream of dapF" FT CDS 40272..41141 FT /transl_table=11 FT /gene="SCO5793" FT /gene_synonym="dapF" FT /product="diaminopimelate epimerase" FT /note="SC4H2.14, dapF, probable diaminopimelate epimerase, FT len: 289 aa; similar to many e.g. DAPF_ECOLI P08885 FT diaminopimelate epimerase (ec 5.1.1.7) (275 aa), fasta FT scores; opt: 312 z-score: 525.5 E(): 4.8e-22, 34.1% FT identity in 287 aa overlap" FT /db_xref="GOA:O69969" FT /db_xref="HSSP:1GQZ" FT /db_xref="InterPro:IPR018510" FT /db_xref="UniProtKB/Swiss-Prot:O69969" FT /protein_id="CAA18330.1" FT /translation="MSTRIAFLKGHGTENDFVIVPDPENALDLPPAAVAALCDRRAGLG FT GDGLLHVVRSAAHPEARGMAAEAEWFMDYRNGDGSVAEMCGNGVRVFARYLQHAGHVTE FT GDLAVATRGGVKTVHIAKNGDVTVGMGRALLPAGDVEVSVGEREWPARNVNMGNPHAVA FT FVADLDHAGDLYAPPSHAPAGAYPDGVNVEFVVDRGPRHVAMRVHERGSGETRSCGTGA FT CAVAVATARRDGLDPAATGTPATYTVDVPGGTLVITERPDGEIEMTGPAVIVAEGEFDS FT AWLEGVLA" FT RBS 41378..41383 FT /note="possible RBS upstream of SC4H2.15" FT CDS 41388..43565 FT /transl_table=11 FT /gene="SCO5794" FT /gene_synonym="SC4H2.15" FT /product="putative kinase/phosphohydrolase" FT /note="SC4H2.15, possible kinase/phosphohydrolase, len: FT 725; similar to many RelA and SpoT genes e.g. RELA_STRCO FT P52560 GTP pyrophosphokinase (ec 2.7.6.5) (847 aa), fasta FT scores; opt: 1049 z-score: 1312.4 E(): 0, 39.5% identity in FT 792 aa overlap and SPOT_ECOLI P17580 FT guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase FT (702 aa), fasta scores; opt:1040 z-score: 867.0 E(): 0, FT 33.8% identity in 695 aa overlap" FT /db_xref="GOA:O69970" FT /db_xref="InterPro:IPR004095" FT /db_xref="UniProtKB/TrEMBL:O69970" FT /protein_id="CAA18331.1" FT /translation="MNAEAVNPASPGPVPPTATGAVTPAPRRKARPRIDLRRLGRAALL FT GSATRSRGLPDAIGHVVEAHRAHHPDADLDPLRRAYVLAESSHRGQMRKSGEPYITHPL FT AVTLILAELGAETTTLTASLLHDTVEDTEVTLDQVGEQFGAEVRYLVDGVTKLEKVDYG FT AAAEPETFRKMLLATGNDVRVMSIKLADRLHNMRTLGVMRREKQERIAKVTRDVLIPLA FT ERLGVQALKSELEDLVFAVMHPEEYAHTRELVQENAARADDPLAAVADEVRGVLREADI FT QAEVLIRPRHFVSVHRVSRKRGTLRGADFGRLLVLVQEDADCYAVLGELHTCMTPVVSE FT FKDFIAVPKFNLYQSLHTAVARAEDGQVVEVLIRTHQMHKVAEAGVVALGNPYAPPAEE FT QSAGDGERADPTRPGWLSRLLDWQRGAPDPDTFWSTLREDLAQDREITVFRPDGGTLGL FT PDGATCVDAAYAQYGEDAHATIGARVNGRLAPMSTVLRDGDTVQLLMGQDPASEPSREW FT LEHAHTPAARIAIQRRLAAHPEAAPEAQEPPRGPAAPEPHAHPDAPRPAPDAAPARPAA FT ADVLVDPPGATVRLAGCCTPVPPDEITGFAVRGGVVTVHRVQCAVVARMKSTGRAEVGV FT RWGESTGCRVTLLAESFGRPHLLADLTEAMALEGAEIVSATVEPPDRQRVRHSYTVVLP FT DAARLPALMRAMRDVAGVYDVSRAQPQPAGA" FT repeat_region 43648..43681 FT /note="34bp imperfect direct_repeat 1" FT repeat_region 43676..43709 FT /note="34bp imperfect direct_repeat 2" FT repeat_region 43704..43737 FT /note="34bp imperfect direct_repeat 3" FT CDS 43816..45354 FT /transl_table=11 FT /gene="SCO5795" FT /gene_synonym="SC4H2.16" FT /product="zinc metalloprotease (putative membrane protein)" FT /note="SC4H2.16, probable zinc metalloprotease (putative FT membrane protein), len: 512 aa; weakly similar to the FT N-terminus of many, longer, aminopeptidases, e.g. FT AMPN_LACLA Q48656 aminopeptidase n (ec 3.4.11.2) (848 aa), FT fasta scores; opt: 304 z-score: 287.5 E(): 8.6e-09, 25.2% FT identity in 440 aa overlap. Contains match to Prosite entry FT PS00142 Neutral zinc metallopeptidases, zinc-binding region FT signature and Pfam match to entry zn-protease PF00099, FT Zinc-binding metalloprotease domain, score 28.22. Contains FT possible hydrophobic membrane spanning region" FT /db_xref="GOA:O69971" FT /db_xref="InterPro:IPR006025" FT /db_xref="UniProtKB/TrEMBL:O69971" FT /protein_id="CAA18332.1" FT /translation="MLHTPHPPTPRLRARSRRRLRAVALLASAVSVCLVAASAPPTPLG FT VGDRLFPQLGNPGYDVAAYDLSFTYSGSNNEPLKAVTTIEARTTADLDRINLDFAHGKV FT DSVEVDGEPAGFATAGEDLVVTPEDALDEGDWTRITVRHSSDPVYSDDRQGGWVRTADG FT LAMANQADVAHLVFPCNDHPSDKARFTFHITAPDGLTAVANGLPTRVDRTGTSTTWTYR FT SPHPMATELAQVSIGRSTVLHRAGPHGLPVRDVVPTEHRAALEPWLEKTPGQITWMEQK FT VGRYPFETYGLLMADATTGFELETQTLTLFERELFTEPAYPKWYVESIMVHELAHSWFG FT NSVSPATWADLWLNEGHATWYEALYAEETADKTVAARMKAAYGASDRWRTAGGPPAAPK FT PPKNGSKTGIFRANVYDGAALVLYALRQEIGRPAFERVERAWVARNQDGTATTADFVRL FT ASETSGRDLGGFFQAWLYGAKTPPMPGHPDWKQNPVEKAAGKQPAKASRNTHGE" FT misc_feature 44797..44844 FT /note="Pfam match to entry zn-protease PF00099, FT Zinc-binding metalloprotease domain, score 28.22" FT misc_feature 44800..44829 FT /note="PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature" FT RBS 45493..45497 FT /note="possible RBS upstream of SC4H2.17" FT CDS 45502..46995 FT /transl_table=11 FT /gene="SCO5796" FT /gene_synonym="SC4H2.17" FT /product="conserved hypothetical protein SC4H2.17" FT /note="SC4H2.17, unknown, len: 497 aa; similar to FT hypothetical proteins from many organisms e.g. HFLX_ECOLI FT P25519 GTP-binding protein HflX (426 aa), fasta scores; FT opt: 904 z-score: 715.0 E(): 1.3e-32, 39.6% identity in 407 FT aa overlap.Contains PS00017 ATP/GTP-binding site motif A FT (P-loop). Contains probable coiled-coil from aa 235 to 271" FT /db_xref="GOA:O69972" FT /db_xref="InterPro:IPR005225" FT /db_xref="UniProtKB/TrEMBL:O69972" FT /protein_id="CAA18333.1" FT /translation="MTSSSSPSQDTKRLAQTYPEGLRADALMEEDVAWNRGNDSQWDGE FT QFDRSDRAALRRVAGLSTELEDVTEVEYRQLRLERVVLVGVWTSGTVQDAENSLAELAA FT LAETAGALVLDGVVQRRDKPDAATYIGSGKAEELRDVVLHTGADTVICDGELSPGQLIH FT LEDVVKVKVIDRTALILDIFAQHAKSREGKAQVALAQMQYMLPRLRGWGQSLSRQMGGG FT KGGGLATRGPGETKIETDRRRIREKMAKMRREIAEMKTGREIKRQERKRHKVPSVAIAG FT YTNAGKSSLLNRLTGAGVLVENALFATLDPTVRRAETPSGRLYTLADTVGFVRHLPHHL FT VEAFRSTMEEVGDSDLILHVVDGSHPVPEEQLAAVREVIRDVGATDVPEIVVINKADMA FT DPLVLQRLLRIEKRAIAVSARTGQNIDQLLALIDNELPRPSVEIEALVPYTHGKLVARA FT HDEGEVISEEHTPEGTLLKVRVHEELAAELAPYVPAPLA" FT misc_feature 46342..46365 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT stem_loop 47025..47070 FT /note="hairpin loop with perfect 23 bp stem" FT CDS complement(47091..48308) FT /transl_table=11 FT /gene="SCO5797" FT /gene_synonym="SC4H2.18c" FT /product="putative secreted protein" FT /note="SC4H2.18c, probable secreted protein, len: 405 aa; FT Contains probable N-terminal signal sequence and FT appropriately positioned PS00013 Prokaryotic membrane FT lipoprotein lipid attachment site. Highly similar to FT upstream CDS SC4H2.19c (409 aa), fasta scores; E(): 0, FT 61.8% identity in 406 aa overlap" FT /db_xref="GOA:O69973" FT /db_xref="InterPro:IPR017909" FT /db_xref="UniProtKB/TrEMBL:O69973" FT /protein_id="CAA18334.1" FT /translation="MRSTPGSAAPRRGRRTALAAAGLVAALTLTATACGGAEQDEADAK FT PGGGASEAADAGGTGGGGGGLAAGLANRLKEHGIDVDRWKDGGWKDWDEDKWLSEAKDF FT VNPVIEGLWEPERMKSAKEADKTVTTKDAAADQGATDPEPTPVEAVAEEKPYHENAAPV FT GKVFFDSPEGSMVCSGTVVKDVNHPGKSNLVWTAGHCVHAGGSGGWYRNIAFVPSYNDY FT GKSEAELANATTTEMAPYGTWWADWAATSDQWIKGGSESGGDGAAYDYSVLHVKPEQGG FT KSLEETVGAALEVDFSAPSATEVSSMGAWGYPAAAPYNGLEMFKCLDRPGRLSLSPSLP FT TMYRIGCTMTGGSSGGGWFRVVDGETKLVSNTSIGPLENTWLAGPQLGPSAEAMYQNMS FT KTYGGQ" FT misc_feature complement(48207..48239) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS complement(48318..48323) FT /note="possible RBS upstream of SC4H2.18c" FT CDS complement(48406..49635) FT /transl_table=11 FT /gene="SCO5798" FT /gene_synonym="SC4H2.19c" FT /product="putative secreted protein" FT /note="SC4H2.19c, probable secreted protein, len: 409 aa; FT Contains probable N-terminal signal sequence and FT appropriately positioned PS00013 Prokaryotic membrane FT lipoprotein lipid attachment site. Highly similar to FT downstream CDS SC4H2.18c (405 aa), fasta scores; E(): 0, FT 61.8% identity in 406 aa overlap" FT /db_xref="GOA:O69974" FT /db_xref="UniProtKB/TrEMBL:O69974" FT /protein_id="CAA18335.1" FT /translation="MRSIRPSFSTRGNRRGRRGTSSAAAAVALVSALALTATACEDGDP FT EAGGDASASASAADDGNGGIRIPDDIKDKLKEHGIDVDDWKNGAWKNWNKDDWLREAQD FT FVNPIIEGLWDPDRMRDAEEPDQEVDENDISGDQGVTDPEPAPVEAEAVPAKYHDNAAT FT AGKLLFDSPKGSMVCSATVVKDPAHPGKSNMVWTAGHCVHAGKSGGWYRNIAFVPSYND FT ADKSVEELQNATKEELAPYGVWWGDWAQTSDQWIEQGGATGGDGASYDFAVIHVTPEKG FT SGGKSLEETVGAALPVDFDAPAVPEIESMKAIGYPAAPPYDGQKLYQCQDKPGRLSLNA FT SDPTMYRIGCTMTGGSSGGGWVAAGSDGKPALVSNTSIGPVTAGWLAGPRLGDEAKGVF FT DAVSGKFAGQ" FT misc_feature complement(49516..49548) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS complement(49644..49647) FT /note="possible RBS upstream of SC4H2.19c" FT CDS 49949..51547 FT /transl_table=11 FT /gene="SCO5799" FT /gene_synonym="SC4H2.20" FT /product="putative aminotransferase" FT /note="SC4H2.20, probable aminotransferase, len: 532; FT similar to many e.g. GABT_ECOLI P22256 4-aminobutyrate FT aminotransferase (426 aa), fasta scores; opt: 355 z-score: FT 385.5 E(): 3e-14, 28.8% identity in 427 aa overlap. FT Contains two repetitive regions: FT GSGSGTGPGSGTGPGTGTGPGTGPGTGPG between aa 82-104, and FT VTVTDAVTVTDAVTDADADAD between aa 241-261, that are not FT present in other aminotransferases. Also contains 2x match FT to Pfam match to entry aminotran_3 PF00202, FT Aminotransferases class-III pyridoxal-phosphate, scores FT 72.94 and 175.90, and TTA leucine codon; a potential target FT for actionof bldA" FT /db_xref="GOA:O69975" FT /db_xref="HSSP:1M0Q" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:O69975" FT /protein_id="CAA18336.1" FT /translation="MPGAPGTSGRVRTAGGRRAVAGSPYGGCAGAGGNAGPVVASEPAA FT GTSTKAHTARVGAGQGRGLHEGAGQGSGMAGSGSGTGPGSGTGPGTGTGPGTGPGTGPG FT AGGRRSAPRRQAAREPAARTYARALPVVPVRARGLTIEGADGRRYLDCVSGAGTLALGH FT NHPVVLDAIRAVLDSGAPLHVMDLTTPVEDAFVTELLRTLPPGLADRARVRFCGPAGTA FT PVDAAVALARAATGRTRVVTVTDAVTVTDAVTDADADADETFLDDDHGGGPGRERPAGL FT LLEPVRSEAGVRPVPDGLVRRLRARAADRAVPLIVDETGTGVGRTGAYWAFEHSGVTPD FT VLVLAKAIGGSLPLAVVVHREDLVEPDRTAGAFRGNQLALAAGAATLAHVREHRLAEHA FT ATLGGRMLTGLRALAAEFTCVGDVRGRGLMAGVELVAPDTAPDVAAHGARPGTAVRPGT FT AAHLATAVRRECLRRGLIVDVTGPRANVVRLLPPLIVTEEQMSAVLDRLTDAVRAVDRD FT RPGGSVPLRGKRGPR" FT repeat_region 50172..50259 FT /note="approx. 15 degenerate 6bp repeats" FT misc_feature 50360..50686 FT /note="Pfam match to entry aminotran_3 PF00202, FT Aminotransferases class-III pyridoxal-phosphate, score FT 72.94" FT repeat_region 50669..50732 FT /note="approx. 11 degenerate 6 bp repeats" FT misc_feature 50774..51427 FT /note="Pfam match to entry aminotran_3 PF00202, FT Aminotransferases class-III pyridoxal-phosphate, score FT 175.90" FT misc_feature 51521..51523 FT /note="TTA leucine codon; potential target for action of FT bldA" FT RBS 51574..51579 FT /note="possible RBS upstream of SC4H2.21" FT CDS 51587..53533 FT /transl_table=11 FT /gene="SCO5800" FT /gene_synonym="SC4H2.21" FT /product="conserved hypothetical protein SC4H2.21" FT /note="SC4H2.21, unknown, len: 648 aa; similar to proteins FT implicated in siderophore biosynthesis eg. SW:RHSC_RHIME FT (EMBL:AF110737) rhizobactin siderophore biosynthesis FT protein RhsC from Rhizobium meliloti (585 aa) fasta scores; FT opt: 1215, Z-score: 1075.6, E(): 3.6e-53, 40.000% identity FT (41.912% ungapped) in 570 aa overlap. Very weak similarity FT to TR:Q47316 (EMBL:X76100) E. coli plasmid pColV-K30 iucA FT gene (575 aa), fasta scores; opt: 695 z-score: 458.0 E(): FT 2.6e-18, 30.1% identity in 555 aa overlap. Contains PS00136 FT Serine proteases, subtilase family, aspartic acid active FT site" FT /db_xref="GOA:O69976" FT /db_xref="InterPro:IPR000209" FT /db_xref="UniProtKB/TrEMBL:O69976" FT /protein_id="CAA18348.1" FT /translation="MHTDPAPEPAFAAPEPAPAGTSAPGTPAAPGPVAAPDAARDAAAE FT SDGTPGTAPRLAPAHGVLPGPRPAPHTRRSAADPLDDLDPCAAAQAAGTENLIRCWARE FT ADVSAPDDGVLHVPLPASGTAFVVPVRYWSPTGAHRFGPPRLSGSPASAPPVDPVTLAA FT LLVRETAGAPGPDGPDLVARVADSVRRTAVFLRDRAGSGERGGPDLFLAAEQALLLGHP FT LHPTPKSREGLTEDEARRYSPELRGSFPLHWLAVAPSVLGTDSAWTERGRPVTAPALTA FT RLAADGPAAPEGYALLPLHPWQFRAVLHRPDVAALLDAGLVRDLGAWGPAWHPTSSVRT FT VRRGGAPAMLKLSLGLHITNSRRENLRKELHRGVEVHRLLRRGLSRQWRSAHPDFDIVR FT DPAWLAVDGADGTPVRGLDVVVRHNPFRPSDDVCCVASLVAPRPHTRLAEVVTRLAGRT FT GRPRGAVAVEWFLRYLHHVVRPVLWLDARAGIALEAHQQNALVLLDADGWPAGGRYRDN FT QGYYFRESRRAELDARLPGIGEHSDTFVADTVADERFAYYLAVNNVFGLIGTFGSERLA FT PEGTLLAAFRRFLRELDSGPDPQGGPLPAHLLDSPVLRCKANLLTRLHGLDELVGPVDT FT QSVYVTIANPLHA" FT misc_feature 52526..52558 FT /note="PS00136 Serine proteases, subtilase family, aspartic FT acid active site" FT RBS 53550..53555 FT /note="possible RBS upstream of SC4H2.22" FT CDS 53563..54258 FT /transl_table=11 FT /gene="SCO5801" FT /gene_synonym="SC4H2.22" FT /product="conserved hypothetical protein" FT /note="SC4H2.22, unknown, len: 231 aa; some similarity to FT C-terminus of Saccharopolyspora erythraea malonyl CoA FT decarboxylase TR:Q54112 (EMBL:L05192) (417 aa), fasta FT scores; opt: 434 z-score: 630.6 E(): 6.6e-28, 40.5% FT identity in 190 aa overlap and similar to the pSymA plasmid FT borne TR:AAK65919 (EMBL:AE007311) Rhizobium meliloti FT (Sinorhizobium meliloti) RhbD rhizobactin siderophore FT biosynthesis protein, 196 aa; fasta scores: opt: 387 FT Z-score: 454.4 E(): 1.1e-17; 35.106% identity in 188 aa FT overlap" FT /db_xref="GOA:O69977" FT /db_xref="InterPro:IPR019432" FT /db_xref="UniProtKB/TrEMBL:O69977" FT /protein_id="CAA18337.1" FT /translation="MNSTDASADDTLDLHLPEEFVALFRSPAHDAAEAGTARAREDLLD FT GIADWGPSDTPAGVFHLVPADLERDVPLIARWMNDPAVAAYWELTGPQSVTADHLRAQL FT AGDGRSVPCVGTLDGVPMSYWEIYRADLDPLARYCPVRPHDTGVHLLIGDGAHRGRGLG FT TELIRAVVDLVLAGRPACTRVLAEPDVRNRQSVAAFLGAGFRPTGEVDLPTKRAVLMIR FT AREAREQSP" FT RBS 54569..54574 FT /note="possible RBS upstream of SC4H2.23" FT CDS 54581..56575 FT /transl_table=11 FT /gene="SCO5802" FT /gene_synonym="SC4H2.23" FT /product="putative ATP-dependent helicase" FT /note="SC4H2.23, probable ATP-dependent helicase, len: 664 FT aa; similar to e.g. DING_ECOLI P27296 probable FT ATP-dependent helicase dinG (716 aa), fasta scores opt: 272 FT z-score: 409.8 E(): 1.3e-15, 26.5% identity in 686 aa FT overlap. Contains PS00017 ATP/GTP-binding site motif A FT (P-loop)" FT /db_xref="GOA:O69978" FT /db_xref="InterPro:IPR014001" FT /db_xref="UniProtKB/TrEMBL:O69978" FT /protein_id="CAA18338.1" FT /translation="MTKPSLPELLHAAVTAVGGTERPGQVAMAEAVEEAIDGGSHLLVQ FT AGTGTGKSLGYLVPALAHGERVVVATATLALQRQLVERDLPRTVDALHPQLRRRPEFAM FT LKGRSNYLCLHRLHEGVPQDEEEGLFDQFEAAAPTSKLGQDLLRMRDWADEAETGDRDD FT LTPGVSDRAWAQVSVSSRECLGASKCAYGAECFAETARERAKLSEVVVTNHALLAIDAI FT EGAPVLPQHEVLIVDEAHELVSRVTGVATGELTPGQVNRAVRRAAKLVNEKAADQLQTA FT AEGFERLMELALPGRLEEVPEDLGYALMALRDACRTVISAIGTTRDKSVQDEDAVRKQA FT LASVESVHDVAERITNGSEWDVVWYERHDRFGASLRVAPMSVSGLLREKLFTDRSVVLT FT SATLKLGGDFNGVGASLGLAPEGTEGDDVPQWKGVDVGSPFDYRKQGILYVAKHLARPA FT RDGDRGDMLDELTELIQAAGGRTLGLFSSMRAAQLAAEELRSRIPEYPILLQGEETLGE FT LIKNFAADPQTCLFGTLSLWQGVDVPGPSCQLVVMDKIPFPRPDDPLMSARQKAVEEAG FT GNGFMAVAATHAALLMAQGAGRLVRASGDRGVVAVLDQRLATARYGSYLKASLPDFWFT FT TDRNQVRKSLAAIDAKARQTEAAGQPESG" FT misc_feature 54716..54739 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(56664..57368) FT /transl_table=11 FT /gene="SCO5803" FT /gene_synonym="lexA" FT /product="SOS regulatory protein" FT /note="SC4H2.24c, lexA, probable SOS regulatory protein FT LexA, len: 234 aa; similar to many LEXA_BACSU P31080 SOS FT regulatory protein LexA/DinR (205 aa), fasta scores; opt: FT 613 z-score: 633.7 E(): 4.5e-28, 46.4% identity in 209 aa FT overlap (active site residues are conserved)" FT /db_xref="GOA:O69979" FT /db_xref="HSSP:1JHC" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/Swiss-Prot:O69979" FT /protein_id="CAA18339.1" FT /translation="MSDAANPEGHKRSLPGRPPGIRADSSGLTDRQRRVIEVIRDSVQR FT RGYPPSMREIGQAVGLSSTSSVAHQLMALERKGFLRRDPHRPRAYEVRGSDQAASVQPT FT DTAGKPAASYVPLVGRIAAGGPILAEESVEDVFPLPRQLVGDGELFVLKVVGDSMIEAA FT ICDGDWVTVRRQPVAENGDIVAAMLDGEATVKRFKREDGHVWLLPHNSAYEPIPGDDAT FT ILGKVVAVLRRV" FT RBS 58010..58015 FT /note="possible RBS upstream of SC4H2.25" FT CDS 58027..58575 FT /transl_table=11 FT /gene="SCO5804" FT /gene_synonym="SC4H2.25" FT /product="conserved hypothetical protein SC4H2.25" FT /note="SC4H2.25, unknown, len: 182 aa; similar to FT hypothetical genes from a wide range of organisms e.g. FT YBAD_ECOLI P25538 hypothetical 17.2 kd protein in tsx-ribG FT (149 aa), fasta scores; opt: 426 z-score: 367.0 E(): FT 3.2e-13, 43.0% identity in 149 aa overlap" FT /db_xref="GOA:O69980" FT /db_xref="InterPro:IPR003796" FT /db_xref="UniProtKB/Swiss-Prot:O69980" FT /protein_id="CAA18340.1" FT /translation="MHCPFCRHPDSRVVDSRTTDDGTSIRRRRQCPDCSRRFTTVETCS FT LMVVKRSGVTEPFSRTKVINGVRKACQGRPVTEDALAQLGQRVEEAVRATGSAELTTHD FT VGLAILGPLQELDLVAYLRFASVYRAFDSLEDFEAAIAELRETTGHPGEEDDTGAGSQE FT NDRGPTGAGQVPEPAGAAD" FT RBS 58735..58739 FT /note="possible RBS upstream of nrdJ" FT CDS 58744..61647 FT /transl_table=11 FT /gene="SCO5805" FT /gene_synonym="nrdJ" FT /product="ribonucleotide reductase" FT /note="SC4H2.26, nrdJ, ribonucleotide reductase, len: 967 FT aa; highly similar to Streptomyces clavuligerus FT TR:E1258368(EMBL:AJ224870) vitamin B12-dependent FT ribonucleotide reductase (951 aa), fasta scores; opt: 5800 FT z-score: 5797.4 E():0, 91.3% identity in 958 aa overlap. FT Contains 2x match to Pfam match to entry ribonucleo_red FT PF00317, Ribonucleotide reductase, scores 75.54 and 86.71" FT /db_xref="GOA:O69981" FT /db_xref="InterPro:IPR013678" FT /db_xref="UniProtKB/Swiss-Prot:O69981" FT /protein_id="CAA18341.1" FT /translation="MTETASGPARSSRAKGTKAGKGLRVERVHTTPGVHPYDEVAWERR FT DVVMTNWRDGSVNFEQRGVEFPEFWSVNAVNIVTSKYFRGAVGTPQREVSLKQLIDRIV FT KTYRKAGEDNKYFASPADAEIFEHELAYALLHQIFSFNSPVWFNVGTPQPQQVSACFIL FT SVDDSMESILDWYKEEGMIFKGGSGAGLNLSRIRSSKELLSSGGNASGPVSFMRGADAS FT AGTIKSGGATRRAAKMVILDVDHPDIEDFIQTKVKEEEKIRALRDAGFDMDLGGDDITS FT VQYQNANNSVRVNDTFMKAVQDGGKFGLTSRMTGEVIEEVDAKALFRKMAEAAWACADP FT GIQYDDTINAWHTCPESGRINGSNPCSEYMHLDNTSCNLASLNLMKFLKDDGKGNQSFD FT AERFSKVVELVITAMDISICFADFPTQKIGENTRAFRQLGIGYANLGALLMATGHAYDS FT DGGRALAGAITSLMTGTSYRRSAELAAIVGPYDGYARNAKPHLRVMKQHSDENAKAVRM FT DDLDTPIWAAATEAWQDVLRLGEKNGFRNSQASVIAPTGTIGLAMSCDTTGLEPDLALV FT KFKKLVGGGSMQIVNGTVPQALRRLGYQEEQIEAIVAHIAENGNVIDAPGLKPEHYEVF FT DCAMGERSISAMGHVRMMAAIQPWISGALSKTVNLPESATVEDVEEVYFEAWKMGVKAL FT AIYRDNCKVGQPLSAKTKTVKDTEKAEITEKTEAAIRETVEKVVEYRPVRKRLPKGRPG FT ITTSFTVGGAEGYMTANSYPDDGLGEVFLKMSKQGSTLAGMMDAFSIAVSVGLQYGVPL FT ETYVSKFTNMRFEPAGMTDDPDVRMAQSIVDYIFRRLALDFLPFETRSALGIHSAEERQ FT RHLETGSYEPSDDELDVEGLAQSAPRAQELVAVATPKAEAEAAKPAPQQAHTSAELVEM FT QLGIQADAPLCFSCGTKMQRAGSCYICEGCGSTSGCS" FT misc_feature 58775..61647 FT /note="approx. 90% match to EMBL:SCAJ4870 AJ224870 FT Streptomyces clavuligerus nrdJ gene, partial CDS from: 2 FT to: 2856" FT misc_feature 59140..59535 FT /note="Pfam match to entry ribonucleo_red PF00317, FT Ribonucleotide reductase, score 75.54" FT misc_feature 59704..60834 FT /note="Pfam match to entry ribonucleo_red PF00317, FT Ribonucleotide reductase, score 86.71" FT CDS complement(61725..62333) FT /transl_table=11 FT /gene="SCO5806" FT /gene_synonym="SC4H2.27c" FT /product="conserved hypothetical protein SC4H2.27c" FT /note="SC4H2.27c, hypotehtical protein, len: 202 aa; FT contains PS00017 ATP/GTP-binding site motif A (P-loop). FT Start site uncertain. Similar to TR:CAC37539 FT (EMBL:AL590982) Streptomyces coelicolor conserved FT hypothetical protein SCIF3.20c, 190 aa; fasta scores: opt: FT 685 Z-score: 693.9 E(): 5.1e-31; 56.111% identityin 180 aa FT overlap " FT /db_xref="GOA:O69982" FT /db_xref="InterPro:IPR003325" FT /db_xref="UniProtKB/TrEMBL:O69982" FT /protein_id="CAA18342.1" FT /translation="MDNRPPPPGSSGGPGGAGAPGKGKSVNGLSKGMGKVEVALRWDPS FT PAGEPPTDLDLVAGTYPAGDPYGTPVYVVHFDSRSPDGTIYLNRDSRDGKGFGFDEVMT FT LELERLDARYARVVVGVAIQQHTEERTFRDVVSPGLRIREGYTDLAADDFAGVPAATAA FT TVAEFVRDEAGAWEFRAGVHGFDGDPAMFTRTMGAARRP" FT misc_feature complement(62259..62282) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 62356..63033 FT /transl_table=11 FT /gene="SCO5807" FT /gene_synonym="SC4H2.28" FT /product="hypothetical protein SC4H2.28" FT /note="SC4H2.28, unknown, len: 225 aa; start site FT uncertain" FT /db_xref="UniProtKB/TrEMBL:O69983" FT /protein_id="CAA18343.1" FT /translation="MRASGPAESGRRRVPWPYDGAVLVKWIRCTVVDRRGFERGQRKWA FT GLPGEPGFRGQGGGWSRGRPDVAHVFAFWESRAFYDSFMARSHDRLASAQAGTFKDAQV FT RLFDYRFDVKTGFEPRFTDADLLRVALCRVHEERSEHYVLMQEKVWNPAMAGSPGMIRG FT LFGEAPGNGYNEYLVLSMWLSAAEHGKYRTERVERLALRAQTEADIAALTGDIVQLEPS FT WTV" FT CDS 63147..63806 FT /transl_table=11 FT /gene="SCO5808" FT /gene_synonym="SC4H2.29" FT /product="conserved hypothetical protein SC4H2.29" FT /note="SC4H2.29, unknown, len: 219 aa; highly similar to FT several eukaryotic hypothetical proteins e.g. Arabidopsis FT thaliana TR:O04035 (EMBL:AC000106) F7G19.18 (281 aa), fasta FT scores; opt: 482 z-score: 1008.5 E(): 0, 47.0% identity in FT 217 aa overlap. Contains PS00175 Phosphoglycerate mutase FT family phosphohistidine signature and Pfam match to entry FT PGAM PF00300, Phosphoglycerate mutase family, score 20.30" FT /db_xref="GOA:O69984" FT /db_xref="InterPro:IPR013078" FT /db_xref="UniProtKB/TrEMBL:O69984" FT /protein_id="CAA18344.1" FT /translation="MARPRRIVLVRHGESIGNVDDTVYEREPDHALALTDRGRAQAEET FT GEGLREVFGSERISVYVSPYRRTHETLRAFRLDPDLIRIREEPRLREQDWGNWQDRDDV FT RLQKAYRDAYGHFFYRFAQGESGADVYDRVGGFLESLFRSFEDPDHPPNVLLVTHGLAM FT RLFCMRWFHWTVAEFESLANPGNAEMRMLVLGADGKYSLDRPFERWRDPEPYGITG" FT misc_feature 63168..63488 FT /note="Pfam match to entry PGAM PF00300, Phosphoglycerate FT mutase family, score 20.30" FT misc_feature 63171..63200 FT /note="PS00175 Phosphoglycerate mutase family FT phosphohistidine signature" FT CDS 63819..64724 FT /transl_table=11 FT /gene="SCO5809" FT /gene_synonym="SC4H2.30" FT /product="putative hydrolase" FT /note="SC4H2.30, possible hydrolase, len: 301 aa; some FT similarity to several e.g. DRAG_RHORU P14300 FT adp-ribosylglycohydrolase (294 aa), fasta scores; opt: 92 FT z-score: 265.8 E(): 1.4e-07, 25.3% identity in 296 aa FT overlap" FT /db_xref="GOA:O69985" FT /db_xref="InterPro:IPR005502" FT /db_xref="UniProtKB/TrEMBL:O69985" FT /protein_id="CAA18345.1" FT /translation="MTLHSSSDGRLDRALSSLRGLSVGDALGSQFFVPANYPLLGRREL FT PPGTWQWTDDTEMACSVVSVLAAHHRIDQDALAHSFAHHHDFDRGYGPAVNRLLRLVRE FT GGDWRELAAALFNGQGSWGNGAAMRIAPLGAWYADDPEQATHQAEISAYPTHQHREAVV FT GAMAVAAAAALAADPAGPPAAHTLLDGVIALVPKSAVGAGLRRARDMLDYGDAATVAAV FT LGCGRRTTAHDTVPFALWSAARALRDYETAFWTTAQVGGDVDTTCAIVGGVIAAGKAGA FT PPAEWAERVEALPAWMTTSA" FT CDS complement(65012..66559) FT /transl_table=11 FT /gene="SCO5810" FT /gene_synonym="SC4H2.31c" FT /product="transmembrane efflux protein" FT /note="SC4H2.31c, probable transmembrane efflux protein, FT len: 515 aa; similar to many diverse efflux proteins e.g. FT CMCT_NOCLA Q04733 cephamycin export protein cmct (486 aa), FT fasta scores; opt: 1059 z-score: 1207.4 E(): 0, 40.2% FT identity in 433 aa overlap, and PUR8_STRLP P42670 puromycin FT resistance protein pur8 (503 aa), fasta scores; opt: 1135 FT z-score: 1187.0 E(): 0, 39.8% identity in 492 aa overlap. FT Contains PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site and Pfam match to entry sugar_tr PF00083, FT Sugar (and other) transporters, score 33.27" FT /db_xref="GOA:O69986" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:O69986" FT /protein_id="CAA18346.1" FT /translation="MTTSSLIKDKKPGAARREGHPGIALAVIAACQLMVVLDATIVNIA FT LPHIQNALEFSTTDLTWVVSAYTLTFGGLLLLGGRAGDILGRRRVFMTGILLFTFASLL FT GGFAQEPWQLLAARVLQGMGGAIASPTSLALITTTFPEGPERNRAFGVFAAVSAGGGAI FT GLLAGGMLTEWLDWRWVLFVNVPIGILIAVLAPLYISESERHSGRFDIAGAVTSTAGMA FT SLVYGFIRAADEGWRDNLTIGSFAAAAVLLLAFVLIEQRAKEPITPLKMFADRNRSGTY FT VIMLSLAAAMFGMFFYIVLFVQNVLGYTPIEAGLAFLPVTVVIALGAGLSQRFLPVFGP FT KPFMIAGSALAALGLGWQALISSDSSYVGGILGPMLIFGFGMGLNFVTLTLTAVSGVAQ FT HEAGAASGLLNAMQQVGGSIGLAILTTVFGTASKDEAAKQVPDFLTNGSPEQKAEFAQT FT HQLPAPWSHDVLAQGISAAFIPAAAMAVLALATAWLVIRVRKSDLDALSGTAGPGMG" FT misc_feature complement(65030..66493) FT /note="Pfam match to entry sugar_tr PF00083, Sugar (and FT other) transporters, score 33.27" FT misc_feature 65963..67080 FT /note="overlap with Cosmid St5B8 from:1 to: 1121" FT misc_feature complement(66467..66499) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT stem_loop 66583..66650 FT /note="hairpin loop with 20/22 bp stem" FT RBS 66734..66737 FT /note="possible RBS upstream of SC4H2.32" FT CDS 66747..67367 FT /transl_table=11 FT /gene="SCO5811" FT /gene_synonym="SC4H2.32" FT /product="transcriptional regulator" FT /note="SC5B8.01, probable transcriptional regulator, FT partial CDS, overlaps and extends SC4H2.32, len: > 140 aa" FT /note="SC4H2.32, probable transcriptional regulator, FT partial CDS, len: >111 aa; similar to many e.g. TR:D1022772 FT (EMBL:D85417) HemR from Propionibacterium freudenreichii FT (243 aa), fasta scores; opt: 262 z-score: 366.7 E(): FT 3.3e-13, 46.5% identity in 101 aa overlap. Contains Pfam FT match to entry tetR PF00440, Bacterial regulatory proteins, FT tetR family, score 29.06" FT /db_xref="GOA:Q8CJQ4" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q8CJQ4" FT /protein_id="CAD55235.1" FT /translation="MVASHWASASAQTPSRRRGAVLERAILEAALDQLGTVGWNGLTME FT GVAAGAQTGKAAVYRRWPSKEDLVADALRSGLPDFDTAPDRGSVREDLLELCRRARDAM FT FSRPGFALRSVIHECDTMQAERFHAVILKGVVEPTLKLLREVIERGMERGEVRRDAVNG FT YVCDAIPAMMMYRSKICASEWTDRELEEMIDQLMIPLLRPDSP" FT misc_feature 66822..66962 FT /note="Pfam match to entry tetR PF00440, Bacterial FT regulatory proteins, tetR family, score 29.06" FT misc_feature 66945..67080 FT /note="overlap with cosmid 4H2 from: 38265 to: 38400" FT CDS 67449..68150 FT /transl_table=11 FT /gene="SCO5812" FT /product="probable ribonuclease HII" FT /note="SC5B8.02, probable ribonuclease HII, len: 233 aa; si FT milar to many e.g. RNH2_ECOLI P10442 ribonuclease hii (EC 3 FT .1.26.4) (213 aa), fasta scores; opt: 444 z-score: 689.5 E( FT ): 3.2e-31, 42.5% identity in 179 aa overlap" FT /db_xref="GOA:O69989" FT /db_xref="HSSP:1EKE" FT /db_xref="InterPro:IPR001352" FT /db_xref="UniProtKB/Swiss-Prot:O69989" FT /protein_id="CAA18510.1" FT /translation="MPYEPPTHTVERSLRATTGAKIIAGVDEVGRGAWAGPVTVCAAIT FT GLRRPPVGLTDSKLLTIKRRTELEVELRTWVTSYALGHASPEEIDAMGMTAALRLAAVR FT ALGTLPVRPDAVILDGKHDYLGAPWRVRTVIKGDQSCIAVAAASVLAKVQRDKMMAELG FT VDHADFGFADNAGYPSPVHKAALEERGPTPHHRLSWAYLDALPQWRHLKKVRSWVEGSV FT PEIEGQLGFDF" FT CDS 68219..68857 FT /transl_table=11 FT /gene="SCO5813" FT /gene_synonym="SC5B8.03" FT /product="hypothetical protein" FT /note="SC5B8.03, unknown, len: 212 aa; highly Proline rich FT in N-terminus" FT /db_xref="UniProtKB/TrEMBL:O69990" FT /protein_id="CAA18511.1" FT /translation="MPLIPEEPQIHEKAQGPRATPASGRTAPTPRPVPGPRPAAPPRPG FT RPGPVRPAPPAQRATRDTAATPGPSGPAAPAAPEATSAAPQIQLIPATPDGALDAAEEA FT VDLLLDSGRTPGDVLVITTGELHPWAAHELSFGDAAYWAQHDAGDDVFYTDATVADRAA FT SRAVVVVALNGGPEAAAVTALTAAHSRAGALLIVCGDPQRINSVLGAGV" FT CDS complement(69172..69786) FT /transl_table=11 FT /gene="SCO5814" FT /gene_synonym="SC5B8.04c" FT /product="hypothetical protein" FT /note="SC5B8.04c, unknown, len: 204 aa" FT /db_xref="UniProtKB/TrEMBL:O69991" FT /protein_id="CAA18512.1" FT /translation="MTFGFAPSSAASFSSSAVSATRMLEPAEWAAAGIPLLRNPREVVT FT GLHSRHRPEPATAVVAVLDPDERLRASASFTSRRAPADGWMFRNALLSQLRRVIPHDLR FT RRTPVRTAVLLYCREGDGRWTQEDGAWMWGLRDACTLHGLRCGAYITLTRDGWQVLGEG FT RGGRRPNAASTPEPFATTESPPPPPRTGGVASDVLRRAAAR" FT RBS complement(69790..69794) FT /note="possible RBS upstream of SC5B8.04c" FT CDS 70074..72233 FT /transl_table=11 FT /gene="SCO5815" FT /product="putative ATP-dependent DNA helicase" FT /note="SC5B8.05, probable ATP-dependent DNA helicase, len:7 FT 19 aa; similar in N-terminal half to many e.g. RECQ_ECOLIP1 FT 5043 atp-dependent dna helicase recq (607 aa), fasta score FT s; opt: 546 z-score: 615.9 E(): 4.1e-27, 35.9% identity in FT 362 aa overlap. Contains PS00690 DEAH-box subfamily ATP-dep FT endent helicases signature and Pfam match to entry helicase FT _C PF00271, Helicases conserved C-terminal domain, score 91 FT .14" FT /db_xref="GOA:O69992" FT /db_xref="HSSP:1OYY" FT /db_xref="InterPro:IPR014001" FT /db_xref="UniProtKB/TrEMBL:O69992" FT /protein_id="CAA18513.1" FT /translation="MDHVELRTEADAVLAELVGDREGSARLREDQWQAVAALVEEHRRA FT LVVQRTGWGKSAVYFVATALLRRRGAGPTVIISPLLALMRNQVEAAARAGIRARTINSA FT NPEDWEAIYGEVERGETDVLLVSPERLNSVDFRDQVLPRLAATTGLLVVDEAHCISDWG FT HDFRPDYRRLRTMLAELPAGVPVLATTATANARVTADVAEQLGTGAGDALVLRGPLDRE FT SLRLGVLVLPDAAHRLAWLGERLGELPGSGIIYTLTVAAAEEIAAFLRQRGYPVASYTG FT KTENADRLQAEEDLLANRVKALVATSALGMGFDKPDLGFVVHVGSPSSPIAYYQQVGRA FT GRGVDHADVLLLPGREDEAIWAYFASVGFPPEEQVRRTLAVLEEAGRPMSLPALEPLVD FT LRRSRLETMLKVLDVDGAVKRVKGGWAATGQAWAYDAERYAWVARQRQAEQQAMREYVS FT TTRCRMEFLQRQLDDEKAAPCGRCDTCAGPWLDPAVSAGALAAATGELDRPGVEVEPRK FT MWPTGLAAVGMDLKGRIPAGRQALTGRALGRLSDIGWGNRLRPLLSAQAADGPVPDDVL FT RAVVTVLADWARSPGGWATGSPDAVARPVGVVAVPSRTRPQLVGSLAEGVARVGRLPLL FT GSLAHTPHADEYAAHRSNSAQRLRALAESFTVPGELAAALAATDGPVLLVDDFTDSGWT FT LAVGARLLRQAGADDVLPLVLALAG" FT misc_feature 70518..70547 FT /note="PS00690 DEAH-box subfamily ATP-dependent helicases s FT ignature" FT misc_feature 70860..71105 FT /note="Pfam match to entry helicase_C PF00271, Helicases co FT nserved C-terminal domain, score 91.14" FT CDS 72399..74003 FT /transl_table=11 FT /gene="SCO5816" FT /gene_synonym="SC5B8.06" FT /product="hypothetical protein" FT /note="SC5B8.06, unknown, len: 534 aa. Contains Probable FT coiled-coil from 234 to 270" FT /db_xref="UniProtKB/TrEMBL:O69993" FT /protein_id="CAA18514.1" FT /translation="MTNHSETTGSSENGDISRAAERGRERADGPMPESPADEHQVTLRT FT PAELADALPYLLGYRPEDSIVLAALRDRDGRGRFGGRARLGIPASPDDWAAAAGQLVHG FT LVTGSERRGVRPEQMVAYLCQEPRPGETGRKVMERLRPLAQKLRVECGALDIPVVEALC FT ISDGRFWSYCCDEEDCCPADGLPVGLPGTSVLAAAATYAGIQVRGSLTELRARMLPREH FT ATAAEQAAALDAAATTLVARILDAGGRAEVAEETLETAERIMRRLAGAPPVSGAPAEDE FT RDDQLLGHDEAAALILGLQDRTTRDRAAAWMEGAEAAPAMRLWRALARRCVGPYGEHAA FT APLTLAGWVAWSTGDELEAREALAMALGADPDYLFARLLHQACNEGLDPESIRRCLREG FT REGGQGTGDTTADDDGRGGAAVEGDREAEPEPARPLSAAPPRRRRRERSLASPSGVRRR FT TRSGGHRPGTETMPPRTMSPRTTPGAGHPGVPRTGRTRPHAPATPVTGREDTRPEVAGP FT EVAGPGERGSHGDRECS" FT RBS 73991..73994 FT /note="possible RBS upstream of SC5B8.07" FT CDS 74009..74893 FT /transl_table=11 FT /gene="SCO5817" FT /product="putative DNA hydrolase with mutT domain" FT /note="SC5B8.07, possible DNA hydrolase with mutT domain, l FT en: 294 aa; similar in part to many hypothetical proteins e FT .g Synechocystis sp. TR:P74291 (EMBL:D90913) (261 aa), FT fasta scores; opt: 241 z-score: 358.0 E(): 9.6e-13, 34.7% FT ident ity in 251 aa overlap. Contains PS00893 mutT domain FT signatu re and Pfam match to entry mutT PF00293, Bacterial FT mutT pro tein, score 39.86" FT /db_xref="GOA:O69994" FT /db_xref="HSSP:1F3Y" FT /db_xref="InterPro:IPR020084" FT /db_xref="UniProtKB/TrEMBL:O69994" FT /protein_id="CAA18515.1" FT /translation="MAEPRTCPGPPGGEAQVGRKWINGEAVAEGSVYRQADDYDRRMPY FT DPSAFPPFAVTVDLVVLTVRRHSLCALAVRRGEPPFQGRWALPGGFVRDGEDLAQAAAR FT ELAEETGLCVHDPAAPSQDNGAHLEQLATYGDPERDPRMRVVSVAHLALAPDLPAPRAG FT GDASNARWAPVEELLEQSGYGRAGEAVAPLAFDHAQILADGVERARSKIEYSSLATAFC FT PPEFTVGELRRVYEAVWSVALDPRNFHRKVTGTPGFLVPTGGTTTRQGGRPAQLFRAGG FT ATLLNPPMLRPEV" FT misc_feature 74219..74344 FT /note="Pfam match to entry mutT PF00293, Bacterial mutT p FT rotein, score 39.86" FT misc_feature 74276..74335 FT /note="PS00893 mutT domain signature" FT CDS 74949..77183 FT /transl_table=11 FT /gene="SCO5818" FT /product="putative ABC transporter" FT /note="SC5B8.08, probable ABC transporter, len: 744 aa; N-t FT erminus is similar to several ABC transporters e.g. NODI_RH FT IGA P50332 from Rhizobium galegae nodulation atp-binding pr FT otein (347 aa), fasta scores; opt: 285 z-score: 225.2 E():2 FT .4e-05, 34.5% identity in 197 aa overlap, and contains PS00 FT 017 ATP/GTP-binding site motif A (P-loop) and Pfam match to FT entry ABC_tran PF00005, ABC transporters, score 135.08. Th FT e C-terminus (approx aa 500-744) contains several probable FT transmembrane domains. In the centre is a repetitive region FT containing 10 copies of a degenerate 7 aa Proline-rich rep FT eat." FT /db_xref="GOA:O69995" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:O69995" FT /protein_id="CAA18516.1" FT /translation="MIQAFGLTSNPRKELPPAVDDVSFEARAGRVTALLGASGAGKTTA FT LRLMLGLQRGRGLTYFRGRPLHRIAHPSREVGVLLGDVPGHPARTVRGHLRMLCAAAGV FT PVRRADEVLESVGLLGLRDERLGSLSRGMDRRLGLACALVPDPHTLVFDDPAGALSAHD FT ARGLHGALRAHAAQGGTVLFSTADPKEAARSADHVVTLERGRVVADQEAAEFSRTRLRP FT RVAVRSPHAARLAALVTKEARAARRSVEVVREGGNRLAVYGSTCADIGEAAFRHGILVH FT QLADEVGDMGPGAGEIPAARQQERREADGERAPGTGTLSAGRPGPETPGVLLPSPATEG FT EPLEDGRGAGHGDGDGPASVAVPNRTPGPRQAPAPVSGHGPEAAPSPSAPAPGPSEPAS FT GPSAPAPGPPAPAAGPSAPAPGPSAPAGGPSAPAPGPSEPASGPSAPAPGPSALDAEPL FT RTPRPFRALVPGSARTREATATLPPPISVRSAPSPLRPLRYELRRAVGVRTGFVTGAVV FT LLVSAVVAVVLARVGHTPQPRLLAAWPRELPLPPAALGAGLLGALAFGDEFRHPALAAD FT RGTVPRRMGLLTAKLLVSAATALLLAALTVGCDAEVLRLFYGPELAQAPADWTALSAGW FT LGLVIGCAWSGVLAAGVFRSTTAGLAAVVAVPVVVVPLVQKVWEGPSVRTAAGLPMRVR FT EVLLTQWPFGGERYVAEVLRLVAQPVGGAMTLSLTALLCAYLLTTLRSRV" FT misc_feature 75033..75560 FT /note="Pfam match to entry ABC_tran PF00005, ABC transporte FT rs, score 135.08" FT misc_feature 75054..75077 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 75408..78887 FT /note="97.5% match to SCA32WHIH AJ003022 Streptomyces coeli FT color whiH gene from: 27 to: 3500" FT repeat_region 76089..76304 FT /note="10 x 21bp degenerate repeats" FT misc_feature 76114..76234 FT /note="sequence from single clone only" FT RBS 77341..77345 FT /note="possible RBS upstream of whiH" FT CDS 77349..78236 FT /transl_table=11 FT /gene="SCO5819" FT /product="sporulation transcription factor, WhiH" FT /note="SC5B8.09, whiH, sporulation transcription factor, le FT n: 295; almost identical to whiH protein TR:E1198707 (EMBL: FT AJ003022) (295 aa), 99.0% identity in 295 aa overlap. First FT of several possible start sites shown. Also similar to man FT y transcriptional regulators, e.g. DGOR_ECOLI P31460 galact FT onate operon transcriptional regulator (177 aa), fasta scor FT es; opt: 240 z-score: 251.2 E(): 8.5e-07, 30.1% identity in FT 173 aa overlap. Contains Pfam match to entry gntR PF00392, FT Bacterial regulatory proteins, gntR family, score 56.85" FT /db_xref="GOA:O50536" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:O50536" FT /protein_id="CAA18517.1" FT /translation="MSTLAHTMMTAARSADSGLANPGELDRYPYAETPAVDRLGAPSWE FT GVEPELGRVGRRTAGNRGRGLHGQLVQQLGQMIVSGDLGADRPLVPEEIGQRFEVSRTV FT VRESLRVLEAKGLVSARPNVGTRVRPVSDWNLLDPDIIEWRAFGPQRDDQRRELSELRW FT TIEPLAARLAAGHGREDVQQRLSDMVGIMGHAMGQGDGLTFSRADTEFHTLLIQIAGNR FT MLDHLSGIVSAALHVSGGPVTGCDRPNDVSIAQHGRIVDALATGDGAAAEAAMRQLLTV FT HPEVERVVPAPREH" FT misc_feature 77556..77732 FT /note="Pfam match to entry gntR PF00392, Bacterial regulato FT ry proteins, gntR family, score 56.85" FT stem_loop 78308..78357 FT /note="hairpin loop with 22/23 bp stem" FT misc_feature 78325..80370 FT /note="98.9% match to SCCSB1 X52983 Streptomyces coelicolor FT hrdB gene for principal sigma factor from: 1 to: 2044" FT RBS 78655..78659 FT /note="possible RBS upstream of hrdB" FT CDS 78665..80200 FT /transl_table=11 FT /gene="SCO5820" FT /gene_synonym="SC5B8.10" FT /gene_synonym="hrdB" FT /product="major vegetative sigma factor" FT /note="SC5B8.10, hrdB, major vegetative sigma factor, len: FT 511 aa; almost identical to, but 70 aa longer than, FT HRDB_STRCO P18183 Streptomyces coelicolor (442 aa), 99.8% FT identity in 442 aa overlap. A more upstream start site has FT been chosen due to extended homology with HrdB sigma FT factors from other Streptomyces species. Contains PS00715 FT and PS00716 Sigma-70 factors family signature 1 and 2 and FT Pfam match to entry sigma70 PF00140, Sigma-70 factors, FT score 477.38. Also contains 7 repeats of the sequence FT AKK(A/T)(A/T) and probable helix-turn-helix motifs from aa FT 471-492 (Score 1644, +4.7 9 SD) and aa 378-399 (Score 1108, FT +2.96 SD)" FT /db_xref="GOA:P18183" FT /db_xref="HSSP:1KU2" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/Swiss-Prot:P18183" FT /protein_id="CAA18518.1" FT /translation="MSASTSRTLPPEIAESVSVMALIERGKAEGQIAGDDVRRAFEADQ FT IPATQWKNVLRSLNQILEEEGVTLMVSAAEPKRTRKSVAAKSPAKRTATKAVAAKPVTS FT RKATAPAAPAAPATEPAAVEEEAPAKKAAAKKTTAKKATAKKTTAKKAAAKKTTAKKED FT GELLEDEATEEPKAATEEPEGTENAGFVLSDEDEDDAPAQQVAAAGATADPVKDYLKQI FT GKVPLLNAEQEVELAKRIEAGLFAEDKLANSDKLAPKLKRELEIIAEDGRRAKNHLLEA FT NLRLVVSLAKRYTGRGMLFLDLIQEGNLGLIRAVEKFDYTKGYKFSTYATWWIRQAITR FT AMADQARTIRIPVHMVEVINKLARVQRQMLQDLGREPTPEELAKELDMTPEKVIEVQKY FT GREPISLHTPLGEDGDSEFGDLIEDSEAVVPADAVSFTLLQEQLHSVLDTLSEREAGVV FT SMRFGLTDGQPKTLDEIGKVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD" FT repeat_region 79049..79153 FT /note="7 x 15bp degenerate repeats" FT misc_feature 79478..80161 FT /note="Pfam match to entry sigma70 PF00140, Sigma-70 factor FT s, score 477.38" FT misc_feature 79568..79609 FT /note="PS00715 Sigma-70 factors family signature 1" FT misc_feature 80075..80155 FT /note="PS00716 Sigma-70 factors family signature 2" FT RBS 80357..80361 FT /note="possible RBS upstream of SC5B8.11" FT CDS 80367..81224 FT /transl_table=11 FT /gene="SCO5821" FT /product="putative serine protease" FT /note="SC5B8.11, probable serine protease, len: 285 aa; FT similar to many members of the trypsin family e.g. FT TRYP_SACERP 24664 from saccharopolyspora erythraea FT (streptomyces erythraeus) (227 aa), fasta scores; opt: 523 FT z-score: 655.1 E(): 2.7e-29, 44.7% identity in 237 aa FT overlap. Contains PS00134 Serine proteases, trypsin family, FT histidine active site, PS00135 Serine proteases, trypsin FT family, serine active site and Pfam match to entry trypsin FT PF00089, Trypsin, score 228.48" FT /db_xref="GOA:O69997" FT /db_xref="HSSP:1EZX" FT /db_xref="InterPro:IPR018114" FT /db_xref="UniProtKB/TrEMBL:O69997" FT /protein_id="CAA18519.1" FT /translation="MRRLFARTLARPLVLAAAATAIPLGSAAPAAADSIVVGGFPVEVS FT DSPWTVALSSRDRFGGTRAGQFCGGVAVGRTTVLTAAHCLGEEVLGSPPEQVDDLRVIA FT GRTDLLSDRGQEIPVRSVWVNPEHDDGTNAGDFAVLTLSEALPAGSVIGMAAEGDPAYT FT PDTAALVYGWGDTSGAGDYANGLHASRVRVLPDASCERAYPGDDDGHYLPATMLCAGEE FT AGGRDACQGDSGGPLVGRGRLIGLVSWGSGCGRPGSPGVYTRVSSILRTLGWDGTAAQQ FT RGGV" FT misc_feature 80472..81182 FT /note="Pfam match to entry trypsin PF00089, Trypsin, score FT 228.48" FT misc_feature 80601..80618 FT /note="PS00134 Serine proteases, trypsin family, histidinea FT ctive site" FT misc_feature 81045..81080 FT /note="PS00135 Serine proteases, trypsin family, serine act FT ive site" FT RBS 81993..81997 FT /note="possible RBS upstream of gyrB" FT CDS 82006..84129 FT /transl_table=11 FT /gene="SCO5822" FT /product="putative DNA gyrase subunit B" FT /note="SC5B8.12, gyrB2, probable DNA gyrase subunit B, len: FT 707 aa; highly similar to many e.g. GYRB_STAAU P20832 staph FT ylococcus aureus. dna gyrase subunit B (EC 5.99.1.3) (643 a FT a), fasta scores; opt: 954 z-score: 2020.9 E(): 0, 45.2% id FT entity in 683 aa overlap. Contains PS00177 DNA topoisomeras FT e II signature and Pfam match to entry DNA_topoisoII PF0020 FT 4, DNA topoisomerase II, score 609.86" FT /db_xref="GOA:O69998" FT /db_xref="HSSP:1AJ6" FT /db_xref="InterPro:IPR006171" FT /db_xref="UniProtKB/TrEMBL:O69998" FT /protein_id="CAA18520.1" FT /translation="MTAETSVPSTALLAGADRDGSNYTARHLLVLEGLEAVRKRPGMYI FT GSTDSRGLMHCLWEIIDNSVDEALGGYCDHIEVILHDDASVEVRDNGRGIPVDVEPKTG FT LSGVEVVMTKLHAGGKFGGGAYAASGGLHGVGASVVNALSARLDIEVDLGGHTHAISFR FT RGVPGTFAKAGPDAKFEAGSGLRKVKKVPKSRRGTRVRYWADRQIFLKDAKLSLDNLHQ FT RARQTAFLVPGLTIVVRDEFGLGDGGSKGEESFRFDGGISEFCEFLAGDRPVCDVLRFS FT GQGSFKETVPVLDEDGQMTPSEVTRDLGVDVALRWGTGYDTTVRSFVNIIATPKGGTHV FT AGFEQAVAKTMNEVLRTKKMLRVAEDDIVKDDALEGLTAVVTVRLAEPQFEGQTKEVLG FT TSAARRIVNNVISRELKAFLTSTKRDAAQQARVVMEKAVAAARTRIAARQHKDAQRRKT FT ALESSSLPAKLADCRSDDVDRSELFIVEGDSALGTAKLARNSEFQALLPIRGKILNVQK FT SSVTDMLKNAECGAIIQVIGAGSGRTFDIDAARYGKIIMMTDADVDGSHIRTLLLTLFH FT RYMRPMVEAGRVFAAVPPLHRIELVQPKKGQDKYVYTYSDRELRDKLMEFQSKNIRYKD FT SIQRYKGLGEMDADQLAETTMDPRRRTLRRINLTDLDSAEQVFDLLMGNDVAPRKEFIS FT SSAATLDRSRIDA" FT misc_feature 82087..83865 FT /note="Pfam match to entry DNA_topoisoII PF00204, DNA topoi FT somerase II, score 609.86" FT misc_feature 83455..83481 FT /note="PS00177 DNA topoisomerase II signature" FT RBS 84339..84343 FT /note="possible RBS upstream of SC5B8.13" FT CDS 84348..84872 FT /transl_table=11 FT /gene="SCO5823" FT /product="putative integral membrane protein" FT /note="SC5B8.13, probable integral membrane protein, len: 1 FT 74 aa; contains five possible transmembrane domains" FT /db_xref="UniProtKB/TrEMBL:O69999" FT /protein_id="CAA18521.1" FT /translation="MSGLFDALVVTAVAGLVITRQFRASRIDTGRRRWVLPVVLGIVAL FT REPGMIDAHHQTAALLLFAAEVIVGLLTGAGWAWTTRIWAEADGAVWSRGTRASVAVWA FT VGIALRAGLYGIGAVLGVRQDGSALLFGLAVTLLVRSGVLAWRVQGPRPAGAPDPAYRD FT AVPRPTWKEPA" FT RBS 84858..84863 FT /note="possible RBS upstream of SC5B8.14" FT CDS 84869..86023 FT /transl_table=11 FT /gene="SCO5824" FT /gene_synonym="SC5B8.14" FT /product="putative two-component sensor" FT /note="SC5B8.14, probable two-component sensor, len: 384 FT aa; N-termius has six possible transmembrane domains, FT C-terminus is similar to histidine kinase domain of many FT two-component sensors e.g. NARQ_ECOLI P27896 FT nitrate/nitrite sensor (566 aa) fasta scores; opt: 220 FT z-score: 227.4 E(): 1.8e-0 5, 32.3% identity in 198 aa FT overlap. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="GOA:O70000" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:O70000" FT /protein_id="CAA18522.1" FT /translation="MTENIWTRWPSREALLPESVSRPRRLLTGAVRLVVFGMLLWGAFT FT SSRLHGWGSAAAAAGLVAAVCVAWAFFRTTLAHRLWPSLALVVLLLAIAVAARSVGFGV FT PALVIWCGCAVVALERLPIAAALPVASVALAFYAAVGDDAWLTTVATAVGLVLAGYVLR FT LDAEARGSAQRLLTQERAARAAEAETAALAERARIAREIHDVLAHSLSAQMVHLEAARL FT LIERDADRQQILDRVVAARGMARDGLAETRQALSALRGDLTPLEEFLAQLVETAGGTAE FT VTITGERRPLPAEASQAVRRVAQEALTNARRHAPGAGVRVRLDYAAREVVLDVRDSGGP FT HGEDTGTGGGYGLLGMRERAELLGGSLRAGPGEEGFVVTLKVPV" FT RBS 86009..86014 FT /note="possible RBS upstream of SC5B8.15" FT CDS 86020..86709 FT /transl_table=11 FT /gene="SCO5825" FT /gene_synonym="SC5B8.15" FT /product="putative two-component response regulator" FT /note="SC5B8.15, probable two-component transcriptional FT regulator, len: 229 aa; similar to many e.g. DEGU_BACSU FT P13800 transcriptional regulator (229 aa), fasta scores; FT opt: 485 z-score: 582.9 E(): 2.8e-25, 37.1% identity in 221 FT aa overlap. Contains PS00622 Bacterial regulatory proteins, FT luxR f amily signature, Pfam match to entry response_reg FT PF00072, Response regulator receiver domain, score 142.77, FT Pfam match to entry GerE PF00196, Bacterial regulatory FT proteins, luxR family, score 80.81, and probable FT helix-turn-helix from aa 180-201 (Score 1092, +2.91 SD)" FT /db_xref="GOA:O70001" FT /db_xref="HSSP:1FSE" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:O70001" FT /protein_id="CAA18523.1" FT /translation="MSEVPGRRPARVVVVDDQTVVREGIVMLLGLLPGVDVVGAAGDGE FT EAVRVVAELAPDVVLMDLRMPRCDGVEATRRIRSEHPGTQVVVLTTYADDESLFPALHA FT GARGYLTKDAGGDEIVRAVHSVLSGDAGLAPSIQRRLLEWLSESESEPRPTGPPEPPDG FT LTTRETEVLVLIAEGLTNHQIASRLRVSTATVKTHINNLFAKTGLKDRAQAVRYAYGKG FT LVRPPGR" FT misc_feature 86047..86388 FT /note="Pfam match to entry response_reg PF00072, Response r FT egulator receiver domain, score 142.77" FT misc_feature 86500..86697 FT /note="Pfam match to entry GerE PF00196, Bacterial regulato FT ry proteins, luxR family, score 80.81" FT misc_feature 86551..86634 FT /note="PS00622 Bacterial regulatory proteins, luxR family s FT ignature" FT CDS 86779..87357 FT /transl_table=11 FT /gene="SCO5826" FT /gene_synonym="SC5B8.16" FT /product="putative membrane protein" FT /note="SC5B8.16, putative membrane protein, len: 192 aa. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="InterPro:IPR007436" FT /db_xref="UniProtKB/TrEMBL:O70002" FT /protein_id="CAA18524.1" FT /translation="MQSSNDPPRGAGGGPECAADHRAVPGRTYVETGQGAGYDGPRYDD FT PWYDALASGWGESAGPAAPGPTVPPMRRSAPAEPPRAAADVYLEVQRSAAFQEVRSRYR FT RFVVPAVAGFFLWYVAYVVAATSAPALMARPVAGAVNVAMVAGLGQFLTTFLLTWAYAR FT HARLRRDRAALELRWDTQELTRGVRGDAS" FT RBS 87341..87344 FT /note="possible RBS upstream of SC5B8.17" FT CDS 87354..88946 FT /transl_table=11 FT /gene="SCO5827" FT /product="putative transmembrane transport protein" FT /note="SC5B8.17, probable transmembrane transport protein, FT len: 530 aa; member of the sodium:solute symporter family, FT similar to many e.g. YJCG_ECOLI P32705 hypothetical protein FT , (549 aa), fasta scores; opt: 935 z-score: 1534.8 E(): 0, FT 43.6% identity in 530 aa overlap. Contains Pfam match to en FT try SSF PF00474, Sodium:solute symporter family, score 338. FT 37" FT /db_xref="GOA:O70003" FT /db_xref="InterPro:IPR019900" FT /db_xref="UniProtKB/TrEMBL:O70003" FT /protein_id="CAA18525.1" FT /translation="MTGDHQTLALLLFSTFVAVTLGITTWVGRRRQGSAEEFYAGGRLF FT SPMENGFAISGDYMSAASFLGISGLIALNGYDGMLYSVGFLVAWLVVLFLVAELVRNCG FT RFTLADVVAARMRERPVRIAAGTSSVTVSVLYLVAQMVGAGSLVALLLGGTSEAARTWT FT VIGVGALMVIYVSLGGMRATTWIQIVKAVLLLGGTVALTALVLVRFHGDVDRLLRTAAE FT RSGHGEAFLAPGLAYGGDWVARFDFISLGLALVLGTAGLPHILSRFYTVPTARAARRSV FT VWSIGLIGGFYLMTIVLGFGAAALVGPNAVRASNAAGNTAVPLLALDLGGGAHSTGGTV FT LFAVVAAVAFATILAVVAGITLASSASVAHDLYASLRRRHSKPRSEVAVARVAAVGIGA FT VAIGLGLLARDLNVAFLVGLAFAVAASANLPVLLYSLFWRGFTTRGAVWAVYGGLVPSV FT VLVLLSPVVSGSPQSLFPDLDFQYFPLQNPGLVSIPLGFVAGWLGTVTSPEVPDEARHA FT ETEVRSLTGAGAV" FT misc_feature 87465..88712 FT /note="Pfam match to entry SSF PF00474, Sodium:solute sympo FT rter family, score 338.37" FT CDS complement(88983..89663) FT /transl_table=11 FT /gene="SCO5828" FT /gene_synonym="SC5B8.18c" FT /product="putative two-component transcriptional regulator" FT /note="SC5B8.18c, probable two-component transcriptional FT regulator, len: 226 aa; similar to many e.g. CITB_KLEPN FT P5268 8 transcriptional regulator from klebsiella FT pneumoniae (23 4 aa), fasta scores; opt: 319 z-score: FT 394.9 E(): 8.3e-15, 30.8% identity in 224 aa overlap. FT Contains Pfam match to entry response_reg PF00072, Response FT regulator receiver domain, score 117.43 and probable FT helix-turn-helix from aa 176- 197 (Score 2073, +6.25 SD)" FT /db_xref="GOA:O70004" FT /db_xref="HSSP:1UDR" FT /db_xref="InterPro:IPR013196" FT /db_xref="UniProtKB/TrEMBL:O70004" FT /protein_id="CAA18526.1" FT /translation="MIEVLVVDDDTRVARVNAAYVEKVPGFHVAAEAHSALEALDAVER FT LPRLDLILLDHYLPDRTGLEVVQEMRRRGRQTDVIMVTAARDVSTVQATMRQGALQYLV FT KPFAFAGLRAKLEAYAELRRTLDGGGEAEQAEVDRIFGALSAPSEPGLPKGHSPTTAEL FT VRQCLLKADGPLSAQEIAERTGVSRQTAQRYLKLLERTGRAVLTLKYGEAGRPEHRYAW FT VTRA" FT misc_feature complement(89316..89660) FT /note="Pfam match to entry response_reg PF00072, Response r FT egulator receiver domain, score 117.43" FT CDS complement(89660..91360) FT /transl_table=11 FT /gene="SCO5829" FT /gene_synonym="SC5B8.19c" FT /product="putative two-component sensor" FT /note="SC5B8.19c, probable two-component sensor, len: 566 FT aa; similar to many e.g. CITA_KLEPN P52687 klebsiella FT pneumoniae sensor kinase (547 aa), fasta scores; opt: 604 FT z-score: 460.1 E(): 2e-18, 27.1% identity in 554 aa FT overlap. Contains Pfam match to entry signal PF00512, FT Signal C terminal domain, score 98.50. Contains possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:O70005" FT /db_xref="HSSP:1OJG" FT /db_xref="InterPro:IPR013767" FT /db_xref="UniProtKB/TrEMBL:O70005" FT /protein_id="CAA18527.1" FT /translation="MPPAPRTVMAMSSTPPVRRLRLGLPRRVFSQVLLMQLAIAAGVAV FT LATGLFLAPLGDQLDDQAMRRALAIAQTTAQQPQVVRDLRTTRPTANGPVQREAERVRE FT ATRAEYVVVMDRQGVRWSHTDPERIGEVVSTDPGQALAGREVMEIDDGTLGRSARGKVP FT LRDGDGEIVGAVSVGIAYDSVRARLIHAIPGLFAYAGGALAVGALASWIISRRVQRQTR FT DLAFSDIAGLLAEREAMLHGIREGVVALDRGGRVRLLNDEAQRLLGIGGEAVGRSPDEA FT LGAGRTADVLAGRVTGTDLLTVRGQRVLVANRMPTDDGGAVATLRDRTELEQLGRELDS FT TRGLIDALRAQDHEHANRMHTLLGLLELEMYDDAVEFVGEVVGDHRVTAEQITERIHDP FT LLAALLVGKATVAAERGVALRVSDRTRLPDRLVDPRGLVTIVGNLVDNALDAAAGTAHA FT RVEVELRAEGRAATLTVRDTGPGIAADHRELVFAAGWSTKEPPAHRERGIGLPLVRRLA FT ERQGGSATVGEAYGGGAEFVVVLPEALTEAAPEPALTVPVTTAAEEESR" FT RBS complement(89671..89676) FT /note="possible RBS upstream of SC5B8.18c" FT misc_feature complement(89738..90367) FT /note="Pfam match to entry signal PF00512, Signal C termina FT l domain, score 98.50" FT CDS complement(91416..92357) FT /transl_table=11 FT /gene="SCO5830" FT /product="conserved hypothetical protein" FT /note="SC5B8.20c, unknown, len: 313 aa; very weak similarit FT y to a hypothetical protein from Synechocystis TR:P72597 (E FT MBL:D90899) (321 aa), fasta scores; opt: 232 z-score: 291.9 FT E(): 4.6e-09, 23.1% identity in 268 aa overlap" FT /db_xref="InterPro:IPR009737" FT /db_xref="UniProtKB/TrEMBL:O70006" FT /protein_id="CAA18528.1" FT /translation="MSTCSTVSRDLDEPVSGTAPVARTWLLLEQPGPWGAKALTSSHLD FT PALGRALDAAAKGTGVRVALVRRPGRHADRGTTAARRVYAAHTVPGNVWLHGATLKDPR FT RLLGLDFAALGRGDHRAFDSVLDGRAHAGDPLALVCTNGKRDRCCALLGRPLAAELAAS FT GAHGVWEVTHLGGHRFSPTVLVLPHGYVYGRVQAHTVKGILHGAREDRIVIEGCRGNSA FT WDRPGQAAELALRSALGEDAAQALTVVRTDGAAPRWEVTLAHRDGRYWRVTVVQGASVP FT PRPESCTASVLGSPARMEATAVRALPVAAVAS" FT CDS complement(92412..93677) FT /transl_table=11 FT /gene="SCO5831" FT /product="putative citrate synthase-like protein" FT /note="SC5B8.21c, citrate synthase-like protein, len: 421 a FT a; similar to citrate synthase from many organisms e.g. CIS FT Y_THIFE P51045 thiobacillus ferrooxidans. citrate synthase FT (386 aa), fasta scores; opt: 387 z-score: 460.4 E(): 1.9e-1 FT 8, 30.2% identity in 384 aa overlap. Contains Pfam match to FT entry citrate_synt PF00285, Citrate synthase, score 81.00 FT and probable helix-turn-helix at aa 17-38 (Score 1757, +5.1 FT 7 SD). Also similar to upstream gene SC5B8.22 (390 aa) E(): FT 4.5e-11, 32.8% identity in 351 aa overlap." FT /db_xref="GOA:O70007" FT /db_xref="HSSP:2CSC" FT /db_xref="InterPro:IPR000551" FT /db_xref="UniProtKB/TrEMBL:O70007" FT /protein_id="CAA18529.1" FT /translation="MRDHEPDHPADSERRLTTREAAELLGVKPETVYAYVSRGQLGSRR FT APGSRGSTFDADEVRALARRNRRDGGINPAPAAGQELTVRTRLTLIENDRFSYRGVDAV FT ELAARHTYEEVAEWLWTGELRPGAAFSAPESSVAVARRAVDALPEHAGPADRLRVAAIA FT AAVTDPLRFDLSEEAVLGTARVLIPTLVAALPPVLRDGHDRDPIARRLWTRLSGQEPDE FT PTLQALDTALGLLVDHDLAASTLAVRVAASARAHAYAAVSAGLGVIEGPLHGAAGGLAH FT RMLLEVLELGSAAPVVAEELRAGRRIPGLGHRLYPGEDPRARALFALLEDVPRAAPAIA FT AARDVQATAARHTPLHANVDLALAVLTVSSGMASTAAETIFAVARTAGWIAHALEEYGE FT RPLRMRPSGLYSGPRPPRPLPE" FT misc_feature complement(92460..93023) FT /note="Pfam match to entry citrate_synt PF00285, Citrate sy FT nthase, score 81.00" FT CDS 93802..94974 FT /transl_table=11 FT /gene="SCO5832" FT /product="putative citrate synthase" FT /note="SC5B8.22, putative citrate synthase, len: 390 aa ; FT similar to citrate synthase from many organisms e.g. CISZ FT _BACSU P39120 bacillus subtilis. citrate synthase i (372 aa FT ), fasta scores; opt: 729 z-score: 877.4 E(): 0, 35.5% iden FT tity in 372 aa overlap. Contains PS00480 Citrate synthase s FT ignature and Pfam match to entry citrate_synt PF00285, Citr FT ate synthase, score 314.55. Also similar to downstream gene FT SC5B8.21c (421 aa) E(): 2.6e-14, 32.4% identity in 352 aa FT overlap" FT /db_xref="GOA:O70008" FT /db_xref="HSSP:1IXE" FT /db_xref="InterPro:IPR019810" FT /db_xref="UniProtKB/TrEMBL:O70008" FT /protein_id="CAA18530.1" FT /translation="MSVNRTAAAATPVEVPRGLAGVVVADTEVGDVRGLEGFYHYRQYS FT AVELARSRGFEDVWHLLVHGELPDARTGAAFAAETAALRRLPDAVRAALPAIAEAGAGS FT GPLAGMRTGLSLLGAALGFRPVYDLSVDQRRQDTLVAAAAVPTLLTALHRLGRGLEPVE FT PREDLSYAANYLYMLTGQEPDEACTRAIEQYLISTIDHGFNASTFTARVIASTGADVAA FT CLAGAVSALSGPLHGGAPSRALDTLDAIGTPDRIDAWIRERVLAGDRIMGFGHAVYRTE FT DPRSRMLREVAQSFGGPRVEFAVEVERQVEAILAELKPGRELHTNVEFYAGVVMELCGL FT PREMFTPTFAAARVVGWSANILEQASDSKIIRPAARYVGPGAPVGVPAVA" FT misc_feature 93853..94920 FT /note="Pfam match to entry citrate_synt PF00285, Citrate sy FT nthase, score 314.55" FT misc_feature 94615..94653 FT /note="PS00480 Citrate synthase signature" FT CDS complement(95115..95351) FT /transl_table=11 FT /gene="SCO5833" FT /product="hypothetical protein" FT /note="SC5B8.23c, unknown, len: 78 aa" FT /db_xref="UniProtKB/TrEMBL:O70009" FT /protein_id="CAA18531.1" FT /translation="MKIVRRIGVPPSARGSTTGSTCPDLFELSDGNFAVIGTEATEALE FT RELPADAARADYERIVVISRETLIRAKADIPDA" FT misc_feature 95343..95444 FT /note="overlap with St9B10 from: 1 to: 102" FT misc_feature complement(95343..102017) FT /note="overlap with Cosmid St5B8" FT RBS complement(95360..95364) FT /note="possible RBS upstream of SC5B8.23c" FT CDS complement(95501..96247) FT /transl_table=11 FT /gene="SCO5834" FT /gene_synonym="SC9B10.01c" FT /product="putative membrane protein" FT /note="SC9B10.01c, putative membrane protein, len: 248 aa. FT Contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:O50508" FT /protein_id="CAA15791.1" FT /translation="MRGADVFQGAGPCDPRFPPCASSPPPRRSAPLGTLEAAAPSIARR FT SPSADPHSTTGGRSPDSGVDMVTRKNATGRFGSAAAGMLLATAGISLAARRRRREAARM FT HERLLELEELAIRRQSLAHQQRMHWELLTRAIDDPSLAEVIDTYDKSIPAERRRQFFYA FT NAWYVNLYHVHRAGLLDQEGLQGRLREFFQSPVFREYWEATRNMRAALDQNSDEARLGL FT VVDALAKDFEDTDTDEWWVVGTPPHD" FT RBS 96325..96331 FT /note="possible RBS upstream of SC9B10.02" FT CDS 96339..97427 FT /transl_table=11 FT /gene="SCO5835" FT /gene_synonym="SC9B10.02" FT /product="putative ATP/GTP-binding protein" FT /note="SC9B10.02, possible ATP/GTP binding protein, len: FT 362 aa; similar in N-terminus to other ATP/GTP binding FT proteins eg. COBW_PSEDE P29937 cobw protein from FT pseudomonas denitrificans (353 aa), fasta scores; opt: 302 FT z-score: 390.2 E(): 1.4e-14, 30.1% identity in 366 aa FT overlap and to TR:Q9RRS7 (EMBL:AE002071) Deinococcus FT radiodurans CobW protein, putative, DR2408, 320 aa; fasta FT scores: opt: 434 Z-score: 475.8 E(): 7.2e-19; 34.412% FT identity in 340 aa overlap. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop)" FT /db_xref="InterPro:IPR011629" FT /db_xref="UniProtKB/TrEMBL:O50509" FT /protein_id="CAA15792.1" FT /translation="MGQRSTPQQIPVVVLAGFLGSGKTTLLNHLLHRSGGSRIGAVVND FT FGSIEIDAMAVAGALGDSTVSLGNGCLCCAVDASELDGYLARLARPEAGIDVIVIEASG FT LAEPQELVRMLLASEQPGIVYGGLVEVVDAAEFDDTRARHPEIDRHLALADLVVVNKTD FT RATDAERVLGLVHSLVGGAAVVPATYGRIDPEFLYDCRPGEERVGQLSFDDLHDHSEGG FT AHADHLHAAYDTLSFVSGLPLDPRRLMRFLDSRPKGLYRIKGYVDFGPYDTRNRYAVHA FT VGRFLRFYPEPWTPAGAAGGSGAPETGRTQLVLIGSGIDAAALGEELDACRRDADAPPA FT DEHGMWGVLRYVADGEEPPDSP" FT misc_feature 96387..96410 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(97424..99880) FT /transl_table=11 FT /gene="SCO5836" FT /gene_synonym="SC9B10.03c" FT /product="DNA gyrase-like protein" FT /note="SC9B10.03c, DNA gyrase-like protein, subunit A, len: FT 818 aa; similarity (strongest in N-terminus, around active FT site) to DNA gyrase subunit A from many organisms eg. FT GYRA_MYCTU Q07702 dna gyrase subunit a (ec 5.99.1.3) from FT Mycobacterium tuberculosis (838 aa), fasta scores; opt: FT 1835 z-score: 1379.9 E(): 0, 42.4% identity in 768 aa FT overlap; and to S. coelicolor GYRA_STRCO P35885 dna gyrase FT subunit a (ec 5.99.1.3) (864 aa), fasta scores; opt: 1886 FT z-score: 1425.4 E(): 0, 42.9% identity in 788 aa overlap. FT Contains probable coiled-coil region from aa 441 to 486" FT /db_xref="GOA:O50510" FT /db_xref="HSSP:1AB4" FT /db_xref="InterPro:IPR013757" FT /db_xref="UniProtKB/TrEMBL:O50510" FT /protein_id="CAA15793.1" FT /translation="MARRSTKTPPPDDSYEERILDIDVVDEMQGSFLEYAYSVIYSRAL FT PDARDGLKPVHRRIVYQMNEMGLRPERGYVKCARVVGEVMGKLHPHGDASIYDALVRMA FT QSFSMRVPLVDGHGNFGSLGNDDPPAAMRYTECRMAEAAGLMTESIDEDTVDFAPNYDG FT QEQEPVALPAAFPNLLVNGASGIAVGMATNMPPHNLREVIAAARHLIRYPNADLDALMK FT HVPGPDLPTGGRIVGLPGIRDAYETGRGTFKIRATVSVETVTARRKGLVVTELPFAVGP FT EKVISKIKDLVGAKKIQGIADVKDLTDRAHGLRLVIEIKNGFVPEAVLEQLYKLTAMEE FT SFGINNVALVDGQPLTLGLKELLEVYLDHRFTVVRRRSEFRRSKRRDRLHLVEGLLTAL FT VDIDEVIRLIRSSENSAQAKQRLMERFSLSDVQTQYILDTPLRRLTKYDRIELESEKDR FT LNAEIEELTRILDSDAELRKLVSAELAAVAKKFGTDRRTTLLESSGAPVAAVPLQVADD FT PCRVLLSSTGLLARTANDEPLVTEAGAKRVKHDLIVSAVPATARGEVGVVTSGGRLLRV FT NVVDLPQLPEAMPTPNLAGGAPLAEFVSLEDDEDVVCLTTLDESSPGLALGTEQGVVKR FT VVPDYPSNKDELEVITLKDGDRIVGGVELRTGDEDLVFITDDAQLLRYQASQVRPQGRP FT AGGVAGVKLADGAKVISFTAVDPAADAVVFTVAGSRGTLDDSVQTTAKLTPFDQYPRKG FT RATGGVRCQRFLKGEDCLAFAWAGATPALAAQKNGTPAQLPDTDPRRDGSGVSLPKTVS FT VVAGPV" FT misc_feature complement(98382..99802) FT /note="69% match EM_BA:SCDNAGYR L27063 Streptomyces FT coelicolor dnaA-gyrA region from 5495 to 6921" FT RBS complement(99890..99895) FT /note="possible RBS upstream of SC9B10.03c" FT RBS 100208..100213 FT /note="possible RBS upstream of SC9B10.04" FT CDS 100216..101568 FT /transl_table=11 FT /gene="SCO5837" FT /gene_synonym="SC9B10.04" FT /product="zinc protease" FT /note="SC9B10.04, probable zinc protease, len: 450 aa; FT weakly similar to many of prokaryotic and eukaryotic origin FT eg. Y4WA_RHISN P55679 hypothetical zinc protease y4wa from FT Rhizobium sp. (512 aa), fasta scores; opt: 617 z-score: FT 325.0 E(): 6.1e-11, 30.8% identity in 426 aa overlap; and FT MPP2_YEAST P10507 mitochondrial processing peptidase beta FT subunit (462 aa), fasta scores; opt: 355 z-score: 321.6 FT E(): 9.4e-11, 25.3% identity in 415 aa overlap. The FT zinc-binding and active site residues are conserved" FT /db_xref="GOA:O50511" FT /db_xref="InterPro:IPR011765" FT /db_xref="UniProtKB/TrEMBL:O50511" FT /protein_id="CAA15794.1" FT /translation="MPMGHTATAQAGSGGLTATEHRLANGLRVVLSEDHLTPVAAVCLW FT YDVGSRHEVKGRTGLAHLFEHLMFQGSAQVKGNGHFELVQGAGGSLNGTTSFERTNYFE FT TMPAHQLELALWLEADRMGSLLAALDDESMENQRDVVKNERRQRYDNVPYGTAFEKLTA FT LAYPEGHPYHHTPIGSMADLDAATLEDARAFFRTYYAPNNAVLSVVGDIDPEQTLAWIE FT KYFGSIASHDGKQPPRDGALPDVMGGELREVVEEEVPARALMAAYRLPEDGTRACDAAD FT LALTVLGGGESSRLYNRLVRRDRTAVAAGFGLLRLAGAPSLGWLDVKTSGDVEVPVIET FT AIDEELARFADEGPTAEEMERAQAQLEREWLDRLGTVAGRADELCRYAVLFGDPQLALT FT AVQRVLEVTAEEVQEVAKARLRPDNRAVLVYEPTASADETDASDENEEAAK" FT RBS 101552..101557 FT /note="possible RBS upstream of SC9B10.05" FT CDS 101565..102953 FT /transl_table=11 FT /gene="SCO5838" FT /gene_synonym="SC9B10.05" FT /product="putative protease" FT /note="SC9B10.05, possible protease, len: 462; weakly FT similar to several hypothetical proteases eg. TR:P73669 FT (EMBL:D90908) processing protease from Synechocystis sp. FT (435 aa), fasta scores; opt: 363 z-score: 293.0 E(): FT 3.7e-09, 26.0% identity in 439 aa overlap" FT /db_xref="GOA:O50512" FT /db_xref="InterPro:IPR011765" FT /db_xref="UniProtKB/TrEMBL:O50512" FT /protein_id="CAA15795.1" FT /translation="MTELATMEFHAQPQAGEPKPWAFPAPERGSLDNGLTVLRCHRPGQ FT QVVAVEVLLDAPLDAEPAGLDGVATIMARAFSEGTDKHSAEDFAAELERCGATLDAHAD FT HPGVRLSLEVPASRLGKALGLLADALRAPAFADGEVERLVRNRLDEIPHELANPSRRAA FT KELSKELFPADARMSRPRQGTEETVETIDSAAVRAFYERHVRPATATAVVVGDLTGVDL FT DALLADTLGAWTGSAAEPRPVPPVTADDRGRVVIVDRPGAVQTQLLIGRTGADRHDRVW FT PAQVLGTYCLGGTLTSRLDRVLREEKGYTYGVRAFGQVLRSAPDGTGAAMLAISGSVDT FT PNTGPALEDLWTVLRKLAAEGLTDAERDVAVQNLVGVAPLKYETAAAVASTLADQVEQH FT LPDDFQATLYRQLAATGTVEATAAVVNAFPVDRLVTVLVGDAAQIKEPVEALGIGEVTV FT VAAE" FT RBS 103306..103310 FT /note="possible RBS upstream of SC9B10.06" FT CDS 103322..104074 FT /transl_table=11 FT /gene="SCO5839" FT /gene_synonym="SC9B10.06" FT /product="putative membrane protein" FT /note="SC9B10.06, putative membrane protein, len: 250 aa; FT similar in part to several hypothetical proteins and to FT TR:P74894 (EMBL:U50357) bacteriocin-like inhibitory FT substance ZooA from Streptococcus zooepidemicus (285 aa), FT fasta scores; opt: 278 z-score: 314.8 E(): 2.3e-10, 37.4% FT identity in 139 aa overlap, Contains probable coiled-coil FT region from aa 72 to 118. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:O50513" FT /db_xref="InterPro:IPR002886" FT /db_xref="UniProtKB/TrEMBL:O50513" FT /protein_id="CAA15796.1" FT /translation="MAFTRATGKHRRPGRVHRTTVRAAGVAALATTGVVGTLAAPALAA FT EPEAEQTGLTPVVTIGDSIADEIDAQALAQKQAAADAAAREAARERAAEAAKEAREAKE FT RAAREAERERLNTFVAPITASYVSTAYQAGSSLWSSGSHTGIDFHASSGTSVHSVGVGT FT VVEAGWGGAYGNQVVIRMHDGTYTQYGHLSSIGVSVGQSVEPGQQIGVSGATGNVTGPH FT LHFEARTSPEYGSDMDPVAYLRSHGVNV" FT RBS 104184..104189 FT /note="possible RBS upstream of SC9B10.07" FT CDS 104195..104890 FT /transl_table=11 FT /gene="SCO5840" FT /gene_synonym="SC9B10.07" FT /product="transcriptional regulator" FT /note="SC9B10.07, probable transcriptional regulator, len: FT 231 aa; similar to many eg. GNTR_BACSU P10585 gluconate FT operon transcriptional repressor (243 aa), fasta scores; FT opt: 199 z-score: 264.8 E(): 1.4e-07, 26.2% identity in 195 FT aa overlap. Contains PS00043 Bacterial regulatory proteins, FT gntR family signature. Contains probable helix-turn-helix FT motif at aa positions 29-49 (Score 1133, +3.05 SD)" FT /db_xref="GOA:O50514" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:O50514" FT /protein_id="CAA15797.1" FT /translation="MRIPAHSVCTAIRDDIVTGVHGRGSRLTEELLARRYGVSRVPVRE FT ALRTLEAEGFVVTRRHAGACVAEPTRREAADLLETRTLLEPLGASRAARRRTDAHLKVL FT RGLVRLGQERAGRGTVDELRSLGGWFHETLARAADSPSLTALLTQLRHKIAWMYVVEAP FT VGPVEHWAEHAAIADAVARGDAERARALMTRHIERSAPGYRLRFAAGGAATERVRNTQH FT SVNTASPLR" FT misc_feature 104279..104344 FT /note="PS00043 Bacterial regulatory proteins, gntR family FT signature" FT CDS complement(105045..105326) FT /transl_table=11 FT /gene="SCO5841" FT /gene_synonym="ptsH" FT /product="phosphocarrier protein hpr" FT /note="SC9B10.08c, ptsH, phosphocarrier protein hpr, len: FT 93 aa; similar to many eg. PTHP_ECOLI P07006 phosphocarrier FT protein hpr (85 aa), fasta scores; opt: 153 z-score: 226.5 FT E(): 1.9e-05, 31.0% identity in 84 aa overlap. Contains FT PS00369 PTS HPR component histidine phosphorylation site FT signature" FT /db_xref="GOA:O50515" FT /db_xref="HSSP:1K1C" FT /db_xref="InterPro:IPR000032" FT /db_xref="UniProtKB/Swiss-Prot:O50515" FT /protein_id="CAA15798.1" FT /translation="MAERRVNVGWAEGLHARPASIFVRAATATGVPVTIAKADGSPVNA FT ASMLAVLGLGAQGGEEIVLASDAEGAEAALERLAKLVAEGLEELPETV" FT misc_feature complement(105267..105290) FT /note="PS00369 PTS HPR component histidine phosphorylation FT site signature" FT RBS complement(105337..105340) FT /note="possible RBS upstream of PS00369 ptsH" FT CDS 105529..108648 FT /transl_table=11 FT /gene="SCO5842" FT /gene_synonym="SC9B10.09" FT /product="conserved hypothetical protein SC9B10.09" FT /note="SC9B10.09, unknown, len: 1039; weak similarity to FT hypothetical proteins from M. jannaschii Y590_METJA Q58010 FT hypothetical protein mj0590 (704 aa), fasta scores; opt: FT 377 z-score: 424.6 E(): 1.7e-16, 24.0% identity in 810 aa FT overlap; and E. coli YFIQ_ECOLI P76594 hypothetical 98.0 kd FT protein in ung-pssa intergenic region (886 aa), fasta FT scores; opt: 267 z-score: 215.7 E(): 7.4e-05, 23.9% FT identity in 833 aa overlap. Contains 12 tandem repeats of FT the aa triplet SGP at aa positions 695 to 707; these are FT not present in Y590_METJA or YFIQ_ECOLI" FT /db_xref="GOA:O50516" FT /db_xref="InterPro:IPR003781" FT /db_xref="UniProtKB/TrEMBL:O50516" FT /protein_id="CAA15799.1" FT /translation="MQTSSDRHEYPAHWEADVVLRDGGTARVRPITVDDAERLVSFYEQ FT VSDESKYYRFFAPYPRLSAKDVHRFTHHDFVDRVGLAATIGGEFIATVRYDRIGAGGTP FT ATAPADEAEVAFLVQDAHQGRGVASALLEHIAAVARERGIRRFAAEVLPANNKMIKVFM FT DAGYTQKRSFEDGVVRLEFDLEPTDRSLAVQYAREHRAEARSVQRLLQPGSVAVVGAGR FT TPGGVGRSILGNIRDAGYTGRLYAVNRAFPEDMKELDGVPACRSVGDIDGPVDLAVVTV FT PAEHVPDVVTACGEHGVQGLVVISAGYADSGPEGRERQRALVRHARTYGMRIIGPNAFG FT IINTSPDVRLNASLAPEMPRAGRIGLFAQSGAIGIALLSRLHRRGGGVTGVTGVSTFVS FT SGNRADVSGNDVLQYWYDDPQTDVALMYLESIGNPRKFTRLARRTAAAKPLVVVQGARH FT GGVAPQGHAVRATRLPHATVSALLRQAGVIRVDTITDLVDAGLLLARQPLPAGPRVAIL FT GNSESLGLLTYDACLSEGLRPQPPLDLTTAASADDFHAALARALADDTCDAVVVTAIPT FT LGEGAAGDAALAEALRSAAAAVPTKPVLVVHVELGGLAEALSAAASTAPQTAQGTAGTT FT AQAAEGTASRAASSAALPADPDAVRRGTPSGPASGAAPASGATPGTAPHAAPGPADQLP FT SGASGPSGPSGPSGPSGPSGPSGPSGPSGPSGPSGPSGPPRPSAAPGRPPGVVRAPEGA FT RLIPAYPAAERAVRALGEAVAYAQWRREAADPGKVPEYEDIDEKGAAQQIAGHLARGQG FT LTLGSQETCDLLGRYGVHVHRALPAATPDDAAAAARTIGYPVALKATAPHLRHRADLGG FT VRLDLADEEQLRRAYAELTELFGKPAELRPVVQGMAPRGVDTVVRAVIDPAAGAVLSFG FT LAGAATQLLGDMAHRLIPVTDRDATSLIRSVRTAPLLFGWRGSAPVDAAALEELLLRVS FT RLVDDHPEVVAVTLEPVVVAPHGLSVLGASVRLAPPPARDDLGPRTLPAY" FT repeat_region 107611..107727 FT /note="13 degenerate repeats of the 9 bp sequence FT TCCGGTCCG" FT RBS 108742..108745 FT /note="possible RBS upstream of SC9B10.10" FT CDS 108754..109341 FT /transl_table=11 FT /gene="SCO5843" FT /gene_synonym="SC9B10.10" FT /product="hypothetical protein SC9B10.10" FT /note="SC9B10.10, unknown, len: 195 aa" FT /db_xref="UniProtKB/TrEMBL:O50517" FT /protein_id="CAA15800.1" FT /translation="MAKTSTTTQGLRAAIERSGYYPALVAEAVEAAVGGEPVRSYLVHQ FT ETTFDQNEVRRHVTVLVLTGNRFIVSHTDEQAADDTSPTPYATTSTESVKLGRISSIVV FT SRVVANPEQYKPGTLPREIVLTIGWGAVSRLDLEPAACGDPNCEADHGYTGSSTADDLS FT LRVSEAGDGPETVRQALTFAQALSEATADSAR" FT CDS 109341..110534 FT /transl_table=11 FT /gene="SCO5844" FT /gene_synonym="SC9B10.11" FT /product="hypothetical protein SC9B10.11" FT /note="SC9B10.11, unknown, len: 397 aa" FT /db_xref="GOA:O50518" FT /db_xref="InterPro:IPR017849" FT /db_xref="UniProtKB/TrEMBL:O50518" FT /protein_id="CAA15801.1" FT /translation="MVQHTAWDTHPEPLPVDSAPVPEYGRGSLADLLPTLAAGLGVPGM FT TAGITELTPADRNCVFLIDGLGWEQLRAHPEDAPFLSSLLGSSRGGTGRPITAGYPATT FT ATSLASVGTGLPPGAHGLPGYTVRNPDTGALMNQLRWQPWTAPGPWQPYPTVFGLAHAA FT GVHAAQVSSPTFANTPLTKVALSGGEFHGRLSGEDRMDCAAEQLARADRALVYTYYAEV FT DGAGHRFGVDSDTWRGQLGHVDRLVQRLAEQLPPRSALYVTADHGMVDVPFDEEHRIDF FT DEDWELKAGVALLGGEGRARHVYAVPGARNDVLFCWREVLGEQFWVASRDEAIAAGWFG FT PGIDDRVYDRIGDVVAAARDDVLVIASEREPKESAMVGNHGSMTPAEQLVPLLEVRS" FT RBS 110566..110569 FT /note="possible RBS upstream of SC9B10.12" FT CDS 110582..111232 FT /transl_table=11 FT /gene="SCO5845" FT /gene_synonym="SC9B10.12" FT /product="putative thimidine kinase" FT /note="SC9B10.12, possible thimidine kinase, len: 216 aa; FT similar to several eg. KITH_ECOLI P23331 thymidine kinase FT (ec 2.7.1.21) (205 aa), fasta scores; opt: 404 z-score: FT 500.0 E(): 1.1e-20, 35.5% identity in 200 aa overlap. FT Contains PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:O50519" FT /db_xref="InterPro:IPR001267" FT /db_xref="UniProtKB/Swiss-Prot:O50519" FT /protein_id="CAA15802.1" FT /translation="MPELVFFSGTMDCGKSTLALQIEHNRSARGLAGMIFTRDDRAGEG FT KLSSRLGLVTDAVEVGDGQDLYAHVVDHLSQGGRVDYVIADEAQFLAPDQIDQLARVVD FT DLDVDVYAFGITTDFRSKLFPGSQRLVELADRVEVLQVEALCWCGARATHNARTVGGVM FT VVEGAQVVVGDVAQSPDEIGYEVLCRRHHRRRMTSATARAAALSPDVLPVTAT" FT misc_feature 110606..110629 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(111262..113331) FT /transl_table=11 FT /gene="SCO5846" FT /gene_synonym="SC9B10.13c" FT /product="putative secreted protein" FT /note="SC9B10.13c, putative secreted protein, len: 689 aa. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="GOA:O50520" FT /db_xref="InterPro:IPR019546" FT /db_xref="UniProtKB/TrEMBL:O50520" FT /protein_id="CAA15803.1" FT /translation="MTDVNRRSVLKVALGGAGLAAFPSVALGATPAAATPHRGPDLVGV FT GDTSITLEFDDRLRSRVALRGVDVTRFDAGEALLVDGGAIDAFTYGGHETRRTRHSRHG FT AGVRVTVWGESATGVRKTVELTSFQRLTGMIVMKVTYANGTGAPLAVTGWRSGAHELLE FT VPGGFHTFSGTTYEDRRDWVRPMTDGFVQENSLGMDASDYGGGTPVATVWRPGAGLSVG FT HVEPVPRMLRLPVRRTAGGASLAVEGDTPVTLRPGRRLTTDTTFLTALPGDHFAPLQRY FT RDYMSDIGRRAPRTPEPALEPMWCAWGYERDFTVEQVVATLPKVREVGLKWAVLDDGWQ FT TNEGDWELDPRKFPRGAPDMRAFTRQIRDAGLRPRLWWAPLAADPESSLYRDHSDMLLL FT DREGNKQRVSWWDAWTLCPAYRPTVDYFVGQVKRFIGDWGYEGLKIDGQHLNAVTPCYN FT PAHGHARPEESTEGLARFWKAVYEAAHEANRDAVVELCPCGTAFAFHNLPYVDQYPSSD FT PLSSYQVRTKGKTMKALMGRGSSYSGDHVELSDGGDDFASSYGVGAVLSTKFTYPAGPD FT EGIVLTPERETLWRRWVNLYEENMLSTGEYRGELYDIGFDKPEAHVVAKGATLHYAFYA FT GRWDGTVELRGLGRGRYRLTDPFNGTSLGTVDARHNTVELAFERFQLIVAEHIG" FT RBS complement(113337..113340) FT /note="possible RBS upstream of SC9B10.13c" FT CDS 113599..114366 FT /transl_table=11 FT /gene="SCO5847" FT /gene_synonym="SC9B10.14" FT /product="transcriptional regulator" FT /note="SC9B10.14, probable transcriptional regulator, len: FT 255 aa; weakly similar to many eg. FARR_ECOLI P13669 fatty FT acyl responsive regulator (240 aa), fasta scores; opt: 220 FT z-score: 345.1 E(): 4.7e-12, 28.0% identity in 236 aa FT overlap. Contains PS00043 Bacterial regulatory proteins, FT gntR family signature" FT /db_xref="GOA:O50521" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:O50521" FT /protein_id="CAA15804.1" FT /translation="MPRGLFADDALPLYERTAARLLDDLRAAAARPGDRLPSERAMVTR FT YAVSRVTLRAALAQLEARGVVRPSSSRGWFVAEPGLFPETVTAPASTVPQVQGFADYAE FT ANGLRTASKVLSATVRPATVAEAEQLRIAPGADLFDLHRLRFLDGLLVVLEHNRLPLSA FT CPALADADFSTASLYATLRAADPPQLPRVADYSVEARHPTAREMELLEIGATMPMLVAT FT QLTSNQEGRPIELTVQVYRGDRYRFRASITNQT" FT misc_feature 113713..113778 FT /note="PS00043 Bacterial regulatory proteins, gntR family FT signature" FT RBS 114567..114570 FT /note="possible RBS upstream of agaZ" FT CDS 114579..115886 FT /transl_table=11 FT /gene="SCO5848" FT /gene_synonym="agaZ" FT /product="tagatose 6-phosphate kinase" FT /note="SC9B10.15, agaZ, possible tagatose 6-phosphate FT kinase, len: 435; highly similar to AGAZ_ECOLI P42903 FT putative tagatose 6-phosphate kinase (426 aa), fasta FT scores; opt: 1637 z-score: 2100.1 E(): 0, 57.5% identity in FT 421 aa overlap" FT /db_xref="GOA:O50522" FT /db_xref="InterPro:IPR012062" FT /db_xref="UniProtKB/TrEMBL:O50522" FT /protein_id="CAA15805.1" FT /translation="MQSPLDEVVRRQKAGRPQGITSVCSAHPLVIEAAVLQARETGGPV FT LVEATSNQVDQYGGYTGLRPADFRDLVYGIATEHGLPLDRVVLGGDHLGPNRWQSLTPD FT EAMGQADALVAAYAEAGFTKIHLDCSFACAGDPAPLTDDVVAERAARLIRVAEDTVGPE FT RAERIRYVIGTEVPTPGGAHETLGALLPTTPEAARTTLEQHRKAFARHGVEGAWPRVMA FT LVVQPAVEFDHLRVVDYRREATEELRKVLDDEPTMVYEAHSTDYQTAEALTALVEDHWA FT VLKVGPGLTFALREALFALAAIEDELVPAGERSRLPEVVERRMLAEPAQWEGYYPGGDA FT EQRLARRYSYSDRMRYYWTDPEIEAAQARLLANLTAAAVPLPLLSAHLPLQYARVRRGE FT LAPRPRELAVDHVRDVLRDYDRAADQNRNQNQREFV" FT RBS 115874..115877 FT /note="possible RBS upstream of agaS" FT CDS 115883..117040 FT /transl_table=11 FT /gene="SCO5849" FT /gene_synonym="SC9B10.16" FT /gene_synonym="agaS" FT /product="AgaS protein" FT /note="SC9B10.16, agaS, len: 385 aa; similar to AGAS_ECOLI FT P42907 agas protein (384 aa) (possible tagatose-6-phosphate FT ketose/aldose isomerase), fasta scores; opt: 960 z-score: FT 1350.4 E(): 0, 45.9% identity in 366 aa overlap" FT /db_xref="GOA:O50523" FT /db_xref="InterPro:IPR014180" FT /db_xref="UniProtKB/Swiss-Prot:O50523" FT /protein_id="CAA15806.1" FT /translation="MTTPPGTLPVDDSAVHTVREIAQQPALWREVDRIVGASREALDAF FT LDPLVARGDLRVVLTGAGTSAFAGQVLQPSLARHLGRRVDAVPTTDLVADPRGCLAEDL FT PTLLVSFARSGDSPESVAATALADQVLSEVHHLVITCNEQGRLAREHTRRPRSHVLLMP FT AASNDRGFAMTSSFTCMTLAALLALGKDARDGVAERLARAAESIIEDGAADRTAGALVD FT RAPERIVFLGSGPLKGLAEESALKVLELTGGTLMAVAESSLGFRHGPKAVLNERSVAVV FT YVSNDPYTRRYDHDIVAELRGNLPVGSVVAVSAESGAGTEGADAWPLPGLGDVEDAALA FT LPAVVYAQLIALRASQARGLRPDNPFPSGEVNRVVQGVTLHSLND" FT RBS 117078..117083 FT /note="possible RBS upstream of SC9B10.17" FT CDS 117090..118082 FT /transl_table=11 FT /gene="SCO5850" FT /gene_synonym="SC9B10.17" FT /product="conserved hypothetical protein SC9B10.17" FT /note="SC9B10.17, unknown, len: 330 aa; similar to FT TR:Q97U07 (EMBL:AE006910) hypothetical protein from FT Sulfolobus solfataricus (298 aa) fasta scores; opt: 370, FT Z-score: 414.6, E(): 1.8e-15, 31.596% identity (34.520% FT ungapped) in 307 aa overlap." FT /db_xref="InterPro:IPR002731" FT /db_xref="UniProtKB/TrEMBL:O50524" FT /protein_id="CAA15807.1" FT /translation="MFLGVDGGGTKTAFCLVDRSGQVVARAQAASSYYFSHGIGLVERV FT LREGVDTVCAAAGLSPADIEYAFFGLPGYGEAARDLPVLDATPRAVLGHDRYACDNDMV FT CGWAGSLGAADGINVISGTGSMTYGERQGRGVRIGGWSESFGDEGSAYWIAIRGLNAFS FT RMSDGRLPEGPLAGVFRSRLGLESDLDVIDVVHNRWQGDRGRIAALSRSVAEAAASGDE FT TAAAILAEAGRELALLVEATRERLGFGPDETVPVSYSGGTFGAAPVLEAFTTGLKSRFA FT GYELRHPLYEPVVGAALYAAKLAGTPLDRPALDALRKASGSPASGEDEQ" FT RBS 118069..118072 FT /note="possible RBS upstream of SC9B10.18" FT CDS 118079..119017 FT /transl_table=11 FT /gene="SCO5851" FT /gene_synonym="SC9B10.18" FT /product="putative integral membrane protein" FT /note="SC9B10.18, possible integral membrane protein, len: FT 312 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="GOA:O50525" FT /db_xref="InterPro:IPR000620" FT /db_xref="UniProtKB/TrEMBL:O50525" FT /protein_id="CAA15808.1" FT /translation="MKNGTRGWILYASLLVLFWGVWGAFSSEPNSRYGYPNEMIYIIWA FT FTMLIPAYFAMRGNTFDRRPVAAMYGLIAGLTGAGGQLLLFQALADGPAYLIFPLVSLS FT PVITVLMATVLLRERITRLAVVGVVAALVAIVLLSIPSGGGDSGAHGPWLPMAILICVA FT WGVQAFCMRKAALVGVNDATTFGWMTISGLLLVPVAFAIMGGFPSGAPWQAPALTAVTQ FT VLNAVGALFLVMAFSRGKATVVAPITNALAPVLTIVLSLAVYQTLPSVWGALGIVLALA FT GSTLMVYSDEKSGESSVAPGAADDDVSSVAR" FT RBS 119107..119110 FT /note="possible RBS upstream of agaY" FT CDS 119122..119970 FT /transl_table=11 FT /gene="SCO5852" FT /gene_synonym="agaY" FT /product="tagatose-bisphosphate aldolase" FT /note="SC9B10.19, agaY, possible tagatose-bisphosphate FT aldolase, len: 282 aa; similar to eg. AGAY_ECOLI P42908 FT tagatose-bisphosphate aldolase agaY (286 aa), fasta scores; FT opt: 585 z-score: 725.0 E(): 3.2e-33, 37.6% identity in 279 FT aa overlap" FT /db_xref="GOA:O50526" FT /db_xref="HSSP:1GVF" FT /db_xref="InterPro:IPR013785" FT /db_xref="UniProtKB/TrEMBL:O50526" FT /protein_id="CAA15809.1" FT /translation="MPLVPTRELVSEAAVAGRAVAAFNVITLEHAEAIASGAQAAGAPV FT ILQISENAVRFHGGRVEPIARAAAEVGKACGVDVALHLDHVTDPRLLHGAADAGFSSAM FT FDAGAQPYAENLAATRAAAQWAHGAGLWLEAELGYVGGKPDAPASAHAAGVRTDPQEAA FT RYVADTGVDALAVAVGSSHAMTERSASLDHALIERLREAVPVPLVLHGSSGVGDDELRR FT AVRAGILKVNVGTALNIAFTGAVRETLAARPDLTDPRPYVARGREAMAETVRALLAVVS FT G" FT CDS complement(120025..120828) FT /transl_table=11 FT /gene="SCO5853" FT /gene_synonym="SC9B10.20c" FT /product="conserved hypothetical protein SC9B10.20c" FT /note="SC9B10.20c, unknown, len: 267 aa; similar to several FT hypothetical proteins eg.TR:Q55078 (EMBL:U50973) OrfA from FT Streptomyces sp. (275 aa), fasta scores; opt: 418 z-score: FT 665.7 E(): 6.4e-30, 37.1% identity in 267 aa overlap" FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/TrEMBL:O50527" FT /protein_id="CAA15810.1" FT /translation="MTDARGSDGRIGETNARRAPGTPCWVSLMVHGPAATHDFYGALFG FT WEFRPGPQQLGPYARALLDGREVAGIGQLPPDRQLPTAWTPYFASDDVNRTAETVRLCG FT GTVGVGPLDAGEAGRMALGSDPAGAVFGVWQAAAHLGTAVTGRPGTPAWNELLTYEAAG FT VAKFYETVFGFELLPDPSADRDYVTLRIEGRPVAGIHGVGDALPRDRGPHWTTYFEVAD FT TDESAARLVDLGGHVLAPAHDTPHGRVATVADPEGARFTLLHAQR" FT RBS complement(120835..120838) FT /note="possible RBS upstream of SC9B10.20c" FT RBS 121053..121056 FT /note="possible RBS upstream of SC9B10.21" FT CDS 121064..121915 FT /transl_table=11 FT /gene="SCO5854" FT /gene_synonym="SC9B10.21" FT /product="thiosulfate sulfurtransferase" FT /note="SC9B10.21, possible thiosulfate sulfurtransferase, FT len: 283 aa; similar to many eukaryotic and prokaryotic FT rhodaneses eg. THTR_HUMAN P25325 thiosulfate FT sulfurtransferase (EC 2.8.1.1) (296 aa), fasta scores; opt: FT 403 z-score: 389.9 E(): 1.5e-14, 35.0% identity in 286 aa FT overlap" FT /db_xref="GOA:O50528" FT /db_xref="HSSP:1URH" FT /db_xref="InterPro:IPR001763" FT /db_xref="UniProtKB/TrEMBL:O50528" FT /protein_id="CAA15811.1" FT /translation="MNAIISASELADELAGPNPPVLLDVRWQLSTAKAAGAPPFDGRAE FT YAAGHLPGAVYVDLDRELASAPGVNGRHPLPEVGEFGAAMRRAGVSHGRPVVVYDGGQG FT WAAARAWWLLRWTGHPNVRVLDGGLPSWEAPLSADVPAPAEGDFTPAPGATGLLDADGA FT AALARSGVLFDARAGERYRGEVEPIDPVGGHIPGAVSAPTTANVAPDGHFLPAEELRAR FT FKTLGATEDGAVGVYCGSGVSAAHEVLALTVAGIPAALYVGSWSEWSSDPARPVAVGPD FT PQ" FT CDS complement(122199..123257) FT /transl_table=11 FT /gene="SCO5855" FT /gene_synonym="SC9B10.22c" FT /product="putative DNA-binding protein" FT /note="SC9B10.22c, unknown, len: 352 aa; similar to FT hypothetical proteins from Mycobacteruim tuberculosis and FT M. leprae; YZ11_MYCTU Q10545 MTCY31.11c (253 aa), fasta FT scores; opt: 444 z-score: 396.4 E(): 6.4e-15, 35.0% FT identity in 246 aa overlap. Contains probable FT helix-turn-helix domain at aa positions 70-91 (Score 1098, FT +2.93 SD)" FT /db_xref="GOA:O50529" FT /db_xref="UniProtKB/TrEMBL:O50529" FT /protein_id="CAA15812.1" FT /translation="MPELRVVAVSNDGTRLVLKAADSTEYTLPIDERLRAAVRGDRPRL FT GQIEIEVESHLRPRDIQARIRAGATAEEVAQMAGIPVDRVRRFEGPVLAERAFMAERAR FT KTPVRRPGENSGPPLGEAVQERLLLRGADKDTVQWDSWRRDDGTWEVLLVYLVAGEPHS FT ASWTYDPPRRLVQAVDAEARALIGESDDLAAPEPSFPFVPRIARLPRDRPLDRTLDREQ FT RERPSLPPPPSEPADDTAATASAERERDSLTSLLEAVPSFRGDLVVPERAPDPVEEPVE FT EPEVEEPPAPAASAGSAYADVLMPRSVASHRDRLTGSTDRQAEADGVRPGRRAAVPSWD FT EIVFGTRRKKQE" FT RBS complement(123262..123267) FT /note="possible RBS upstream of SC9B10.22c" FT CDS 123730..124614 FT /transl_table=11 FT /gene="SCO5856" FT /gene_synonym="SC9B10.23" FT /product="hypothetical protein SC9B10.23 (putative membrane FT protein)" FT /note="SC9B10.23, unknown ATP/GTP binding protein (putative FT membrane protein), len: 294 aa; contains PS00017 FT ATP/GTP-binding site motif A (P-loop). Contains possible FT hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:O50530" FT /protein_id="CAA15813.1" FT /translation="MRERSDDAGVADVGSKGESRRIDLSVPQVAGSALAAVVAAKLASS FT FGVYGTIAGAGLISVVATCGGSVLQHFFKRTGEQIRVKRTVAAVRIDGRTASVPAATPD FT PNPASASGDFTEGTVYRTRTRGWRRPLVAAALVFGVTMAGITVYEVASGQNLSGGHSTT FT VGSAFTGHGKSAADSGESGESGDSGGTEDPQDGRDSGDSGDANDSGSGSEAPAPTPSGS FT PDATDGSPSSGAGSTEGGGTESSPTPTRDAGGDEEAGGTGAPDPDASATAPEPGASSRS FT GTGGQGQDGPAAP" FT misc_feature 124228..124251 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(124538..125875) FT /transl_table=11 FT /gene="SCO5857" FT /gene_synonym="SC9B10.24c" FT /product="FAD-dependent oxidoreductase" FT /note="SC9B10.24c, probable FAD-dependent oxidoreductase, FT len: 445 aa; similar to several eg. GGLO_RAT P10867 FT l-gulonolactone oxidase (ec 1.1.3.8) (439 aa), fasta FT scores; opt: 854 z-score: 973.6 E(): 0, 33.6% identity in FT 440 aa overlap. Contains PS00862 Oxygen oxidoreductases FT covalent FAD-binding site, and possible transmembrane FT anchor at approx. 170-200 aa" FT /db_xref="GOA:O50531" FT /db_xref="InterPro:IPR006094" FT /db_xref="UniProtKB/TrEMBL:O50531" FT /protein_id="CAA15814.1" FT /translation="MSSTRTASGRTSGRNGTWRNWGGNVSARPAREVTPASVDELADAV FT RRAAEDGQRVKAVGTGHSFTSIAATDGVLIRPQLLTGIRSIDRDAMTVTVEAGTPLKRL FT NMALAREGLSLTNMGDIMEQTVSGATSTGTHGTGRDSASIAAQIRGLELVTADGSVLTC FT SADENPEVFAAARIGLGALGVVTAITFAVEPVFLLTAREEPMPFDRVLADFDALWSENE FT HFEFYWFPHTNSTNTKRNNRSAGPERPVGRFQGWLDDEFLSNGLFQAVNWVGRAAPATI FT PSIARISSRALSARTYTDTPYKVFTSPRRVRFVEMEYAVPREAVVEVLRELRTMVDRSR FT LRISFPVEVRTAPADDITLSTASARDSAYIAVHMFRGTPYQAYFTAAERIFTAHEGRPH FT WGKVHTRDAGYFSRVYPRFGEFTALRDRLDPDRLFQNDYLRRVLGP" FT misc_feature complement(125690..125791) FT /note="PS00862 Oxygen oxidoreductases covalent FAD-binding FT site" FT CDS complement(125817..126998) FT /transl_table=11 FT /gene="SCO5858" FT /gene_synonym="SC9B10.25c" FT /product="putative integral membrane protein" FT /note="SC9B10.25c, unknown, probable integral membrane FT protein, len: 393 aa; similar to TR:Q9I1K4 (EMBL:AE004652) FT Pseudomonas aeruginosa hypothetical protein PA2269, 401 aa; FT fasta scores: opt: 1176 Z-score: 1266.8 E(): 6.3e-63; FT 50.678% identity in 369 aa overlap" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:O50532" FT /protein_id="CAA15815.1" FT /translation="MPLSMMGIGVVTMISQLTGRYGLAGALSATIALAAAVAGPQVSRL FT VDRYGQRRVLRPATLVSLTAAAVLLPAAHYGWPDWVLFAACVGIGCVPSLGAMVRARWA FT ALYRGTPQLHTAYSFESVVDEVCFIFGPIISIGLSTAWFPEAGPLLAACFLATGVFWLT FT SQRATEPEPHPREHKGGGTALRSRGLQVLVGTFAATGTIFGAIDVVTVAFAEEQGHKAA FT ASLVLALYAAGSCTAAMIFGLLRFAGPPERRWLLGVCAMAVSMIPLLLVGNLPFLAAAL FT FVAGLSIAPTMITTMSLIEEHVPRTQLTEGMTWVSTGLAVGVALGSSAGGWVIDASGAR FT AGYGVPAVAGAVAVAVGFLGYRRLKRPEPRRGGTVEQHTHGERQDERPERHMA" FT RBS complement(125881..125885) FT /note="possible RBS upstream of SC9B10.24c" FT RBS 127225..127228 FT /note="possible RBS upstream of hemH" FT CDS 127236..128363 FT /transl_table=11 FT /gene="SCO5859" FT /gene_synonym="hemH" FT /gene_synonym="SC9B10.26" FT /product="ferrochelatase" FT /note="SC9B10.26, hemH, probable ferrochelatase, len: 375 FT aa; similar to many eg. TR:D1022769 (EMBL:D85417) FT ferrochelatase (EC 4.99.1.1) from Propionibacterium FT freudenreichii (352 aa), fasta scores; opt: 491 z-score: FT 894.8 E(): 0, 42.5% identity in 369 aa overlap" FT /db_xref="GOA:O50533" FT /db_xref="InterPro:IPR019772" FT /db_xref="UniProtKB/Swiss-Prot:O50533" FT /protein_id="CAA15816.1" FT /translation="MPDVLDASPYDALLLLSFGGPEGPDDVVPFLENVTRGRGIPKERL FT KEVGQHYFLFGGVSPINDQNRALLDALRKDFAEHGLDLPVYWGNRNWAPYLTDTLREMV FT GDGRRRILVLATSAYASYSGCRQYRENLADALAALESEGLELPKIDKLRHYFNHPGFVE FT PMVDGVVRSLAELPAEVRDGAHIAFCTHSIPTSAADGSGPVEEHGDGGAYVRQHLDVAR FT LIADAVRERTGVDHPWQLVYQSRSGAPHIPWLEPDICDHLEERQAAGVPAVVMAPIGFV FT SDHMEVLYDLDTEATAKAEELGLPVRRSATVGADPRFAAAVRDLVLERAGDERGQEVTP FT CALGTLGASHNLCPVGCCPARAPRPAAAGADSPYA" FT RBS 128363..128367 FT /note="possible RBS upstream of SC9B10.27" FT CDS 128372..129190 FT /transl_table=11 FT /gene="SCO5860" FT /gene_synonym="suhB" FT /gene_synonym="SC9B10.27" FT /product="extragenic suppressor protein homolog" FT /product="SuhB protein" FT /note="SC2E9.01, suhB, probable extragenic suppressor FT protein, partial CDS, len: >209 aa, similar to eg. FT SUHB_ECOLI P22783 extragenic suppressor protein Suhb (267 FT aa), fasta scores; opt: 448 z-score: 565.9 E(): 2.5e-24, FT 41.0% identity in 212 aa overlap, and to eg. MYO2_LYCES FT P54927 myo-inositol-1(or 4)-monophosphatase (265 aa), FT fasta scores; opt: 359 z-score: 450.8 E(): 6.6e-18, 38.7% FT identity in 199 aa overlap. Contains PS00629 and PS00630 FT Inositol monophosphatase family signatures 1 and 2 and Pfam FT match to entry inositol_P PF00459, Inositol monophosphatase FT family, score 64.03. Overlaps and extends ORF from FT neighbouring cosmid SC9B10.27" FT /note="SC9B10.27, suhB gene homolog, partial CDS, len > 96 FT aa; similar to E.coli SUHB_ECOLI P22783 extragenic FT suppressor protein Suhb (267 aa), fasta scores; opt: 186 FT z-score: 333.9 E(): 1.9e-11, 40.0% identity in 85 aa FT overlap; and to MYOP_HUMAN P29218 myo-inositol-1(or FT 4)-monophosphatase (277 aa), fasta scores; opt: 180 FT z-score: 267.3 E(): 9.9e-08, 37.2% identity in 94 aa FT overlap" FT /db_xref="GOA:Q8CJQ3" FT /db_xref="HSSP:2HHM" FT /db_xref="InterPro:IPR017955" FT /db_xref="UniProtKB/TrEMBL:Q8CJQ3" FT /protein_id="CAD55236.1" FT /translation="MTDVTPDPLRADLLKIAQEAAHRAGELLRDGRPADLAVAATKSSP FT IDVVTEMDIAAEKLITGLIAERRPDDGFLGEEGAAMEGTSGSRWVIDPLDGTVNYLYGL FT PTWAVSIAAEQDGERVAGVVVAPMRGESYHAVLGGGAWATGAWEGERRLVCRSAAPLDQ FT ALVSTGFNYVADVRAEQAEIARRLIPLVRDIRRGGSAAIDLCDVAAGRLDGYYERGLHP FT WDLAAGDLIAREAGAVTGGRPGERPTGALTIAATPAVFEPLQRLLTDFGA" FT misc_feature 128636..128677 FT /note="PS00629 Inositol monophosphatase family signature 1" FT misc_feature 128657..128854 FT /note="Pfam match to entry inositol_P PF00459, Inositol FT monophosphatase family, score 64.03" FT misc_feature 129038..129082 FT /note="PS00630 Inositol monophosphatase family signature 2" FT RBS 129505..129508 FT /note="possible RBS upstream of SC2E9.02" FT CDS 129515..130081 FT /transl_table=11 FT /gene="SCO5861" FT /gene_synonym="SC2E9.02" FT /product="hypothetical protein SC2E9.02" FT /note="SC2E9.02, unknown, len: 188 aa; not predicted by FT FramePlot" FT /db_xref="UniProtKB/TrEMBL:O54129" FT /protein_id="CAA16470.1" FT /translation="MLPDPATRPAPAAHPRCAAVLPGTAPRAPHPPSPTRAGNSPQDGK FT AHDEAPALDLAGASSCAGRSGVGRADLHTVLGSETAQIVELAQLHLDKELVALVAGPGQ FT VGLGRLYALQKSCGESVHAAPPRPGSWVVGTGVCRSEGAITPPVECPALPCRAATVPDT FT HARSAEADRGVPRGNAVQAERDRGV" FT stem_loop 129650..129699 FT /note="hairpin loop with 20/21 bp stem" FT misc_feature 129851..132665 FT /note="99.9% match to EMBL:SLCUTRS X58793 S.lividans cutR FT gene and cutS gene from: 1 to: 2815" FT RBS 130295..130299 FT /note="possible RBS upstream of cutR" FT CDS 130308..130961 FT /transl_table=11 FT /gene="SCO5862" FT /gene_synonym="SC2E9.03" FT /gene_synonym="cutR" FT /product="two-component regulator CutR" FT /note="SC2E9.03, cutR, two-component regulator CutR, len: FT 217 aa; identical to CUTR_STRLI Q03756 transcriptional FT regulatory protein CutR from Streptomyces lividans (217 FT aa). Contains Pfam match to entry trans_reg_C PF00486, FT Transcriptional regulatory proteins, C terminal, score FT 74.36" FT /db_xref="GOA:P0A4I1" FT /db_xref="HSSP:1KGS" FT /db_xref="InterPro:IPR001789" FT /db_xref="UniProtKB/Swiss-Prot:P0A4I1" FT /protein_id="CAA16471.1" FT /translation="MRVLVVEDEQLLADAVATGLRREAMAVDVVYDGAAALERIGVNDY FT DVVVLDRDLPLVHGDDVCRKIVELGMPTRVLMLTASGDVSDRVEGLEIGADDYLPKPFA FT FSELIARVRALGRRTSVPLPPVLERAGIKLDPNRREVFRDGKEVQLAPKEFAVLEVLMR FT SEGAVVSAEQLLEKAWDENTDPFTNVVRVTVMTLRRKLGEPPVIVTVPGSGYRI" FT misc_feature 130503..130709 FT /note="Pfam match to entry trans_reg_C PF00486, FT Transcriptional regulatory proteins, C terminal, score FT 74.36" FT CDS 130968..132212 FT /transl_table=11 FT /gene="SCO5863" FT /gene_synonym="SC2E9.04" FT /gene_synonym="cutS" FT /product="two-component sensor (kinase)" FT /note="SC2E9.04, cutS, two-component sensor (kinase), len: FT 414 aa; identical to SW:CUTS_STRLI (EMBL:Q03757) CutS FT protein from Streptomyces lividans (414 aa). Contains Pfam FT match to entry signal PF00512, Signal C terminal domain, FT score 191.45. Contains possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:P0A4I7" FT /db_xref="HSSP:1BXD" FT /db_xref="InterPro:IPR005467" FT /db_xref="UniProtKB/Swiss-Prot:P0A4I7" FT /protein_id="CAA16472.1" FT /translation="MATTPAPPGAPPKPTWDPRSATPLPWLRPTIRIRLTLLYGGMFLI FT AGILLLSIIYLLAAQAVRTGNEPLYKIVDFTDLKVSSSTCPVVDNGGLSLSDFNAAISD FT CMDHQRKVALDNLLSRSLLALLGLAVIAFAFGYAMAGRVLSPLGRITRTARAVAGSDLS FT RRIELDGPDDELKELADTFDDMLERLQRAFTAQQRFVGNASHELRTPLAINRTLLEVHL FT SDPGAPVELQQLGKTLLATNERSELLVEGLLLLARSDNQIVERKPVDLAEVAGQAIDQV FT HAEAESKGVEVRGTREAAVVQGNGVLLERIALNLVQNAVRYNVAGQGWVEVATAVENGQ FT AVLVVTNTGPVVPAYEVDNLFEPFRRLRTERTGSDKGVGLGLSIARSVARAHGGHISAQ FT PREGGGLVMRVTLPV" FT misc_feature 131340..131966 FT /note="Pfam match to entry signal PF00512, Signal C termial FT domain, score 191.45" FT RBS 132607..132610 FT /note="possible RBS upstream of SC2E9.05" FT CDS 132618..132914 FT /transl_table=11 FT /gene="SCO5864" FT /gene_synonym="SC2E9.05" FT /product="conserved hypothetical protein" FT /note="SC2E9.05, unknown, len: 98 aa; highly similar to FT hypothetical proteins from Mycobacterium tuberculosis and FT M. leprae eg. TR:O07201 (EMBL:Z96072) MTCY05A6.20C (100 FT aa), fasta scores; opt: 465 z-score: 814.5 E(): 0, 71.4% FT identity in 98 aa overlap" FT /db_xref="UniProtKB/TrEMBL:O54130" FT /protein_id="CAA16473.1" FT /translation="MATDYDTPRKTDDDVDSDSLEELKARRNDKSASAVDVDEFEAAEG FT LELPGADLSNEELAVRVLPKQQDEFTCMSCFLVHHRSQLAREKNGQPICRDCD" FT CDS 132928..133881 FT /transl_table=11 FT /gene="SCO5865" FT /gene_synonym="SC2E9.06" FT /product="hypothetical protein SC2E9.06" FT /note="SC2E9.06, unknown, len: 317 aa" FT /db_xref="UniProtKB/TrEMBL:O54131" FT /protein_id="CAA16474.1" FT /translation="MTGSTPPWKRRFSRRGADQGPSDGPYSARDDERGPTDTGKAPLEP FT VADRSDLPATTRPPAPAARRRAAAFREKAGQGVRNGGARARAALGHLADRIIDLAPRVP FT VRDLAALRRQFPGLGPEEIADRLVAGAAKGTATVGAGIGAAAMLPVPPAMPTELAAEIT FT GVAAIELKLIAELHEVYGVRPPGGLAQRSTAYLNSWSDERGVDVSKPSTLGSAMNSHMK FT RQLRQQIMKRMVRDLPNLMPFMVGAAVGAVMNRRDTRKLAARIRTDLRKNQVAWSALGD FT LPALERPQDALDMGEITKGIGPGRPGRGENFGKDER" FT CDS complement(133895..134359) FT /transl_table=11 FT /gene="SCO5866" FT /gene_synonym="SC2E9.07c" FT /product="putative membrane protein" FT /note="SC2E9.07c, putative membrane protein, len: 154 aa; FT similar to hypothetical proteins from Mycobacterium FT tuberculosis and M. leprae e.g. TR:O07200 (EMBL:Z96072) FT MTCY05A6.19 (161 aa), fasta scores; opt: 230 z-score: 264.3 FT E(): 1.6e-07, 35.7% identity in 154 aa overlap. Contains FT possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:O54132" FT /protein_id="CAA16475.1" FT /translation="MQLSSAPYEERLTAPRSWWLVSFLVGLAFALILLPFGTLPMLGGL FT AGGTAVAAVAASSYGAVRIRVVGDSLIAGEAKVPLSALGEAEILDPEEARAWRTYKADT FT RAFLLLRAYIPRAVRVLVTDPQDPTPYLYLSTREPERLIEALEAAKAAAA" FT RBS 134405..134408 FT /note="possible RBS upstream of SC2E9.08" FT CDS 134417..135001 FT /transl_table=11 FT /gene="SCO5867" FT /gene_synonym="SC2E9.08" FT /product="hypothetical protein SC2E9.08" FT /note="SC2E9.08, unknown, len: 194 aa" FT /db_xref="InterPro:IPR006683" FT /db_xref="UniProtKB/TrEMBL:O54133" FT /protein_id="CAA16476.1" FT /translation="MSGTSPGLQPPADAVKPVRHPDAPAPGELLGAHYGQCFGCGGDQP FT HGLHLQARAGEGVSITAEFTVRPAHQGAPGLAHGGVLATALDETLGSLNWLLRTIAVTG FT RLETDFRRPVPVDTTLYLEAEVTAVAGRKIYSTATGRIGGPDGSVAVRADALFIEVKVD FT HFVQNGREEEIRAAMDDPDQLRRARAFEVNP" FT RBS 134987..134991 FT /note="possible RBS upstream of dut" FT CDS 134998..135549 FT /transl_table=11 FT /gene="SCO5868" FT /gene_synonym="dut" FT /gene_synonym="SC2E9.09" FT /product="deoxyuridine 5'-triphosphate nucleotidohydrolase" FT /note="SC2E9.09, dut, probable deoxyuridine 5'-triphosphate FT nucleotidohydrolase, len: 183 aa; similar to many eg. FT DUT_LYCES P32518 deoxyuridine 5'-triphosphate FT nucleotidohydrolase (169 aa), fasta scores; opt: 299 FT z-score: 371.4 E(): 1.7e-13, 37.9% identity in 140 aa FT overlap" FT /db_xref="GOA:O54134" FT /db_xref="HSSP:1MQ7" FT /db_xref="InterPro:IPR008181" FT /db_xref="UniProtKB/Swiss-Prot:O54134" FT /protein_id="CAA16477.1" FT /translation="MSRAGLEVLIRRVDPDVPLPAYAQPGDAGADLRTTVERELAPGER FT AVLPTGVSVALPEGYAAFVHPRSGLAARCGVALVNAPGTIDAGYRGEIKVIVVNLDPRE FT SVRFERFDRIAQLVVQQVERVRFRQVAELPGSARAEGGFGSTGGHAGLDPASGTSGQVA FT EGGPTGGNRYASVVSDREGQ" FT RBS 135539..135543 FT /note="possible RBS upstream of SC2E9.10" FT CDS 135551..136303 FT /transl_table=11 FT /gene="SCO5869" FT /gene_synonym="SC2E9.10" FT /product="hypothetical protein SC2E9.10" FT /note="SC2E9.10, unknown, len: 250 aa; similar to FT hypothetical proteins from Mycobacterium tuberculosis and FT M. leprae eg. TR:O07198 (EMBL:Z96072) MTCY05A6.17C (259 FT aa), fasta scores; opt: 213 z-score: 435.8 E(): 4.5e-17, FT 28.2% identity in 255 aa overlap. Contains possible FT coiled-coil domain from aa 1-40" FT /db_xref="UniProtKB/TrEMBL:O54135" FT /protein_id="CAA16478.1" FT /translation="MFGRRKKNDAAEDAAGETEQVVDSVDTEADEERERVRLEPEPRPD FT GPWDSTEVRDPGEGRVDLGGLFIPGVDGMELRVEVAGDAIVAATVVLRDSAIQLQGFAA FT PKREGIWGEVREEIGSGITQQGGIIDEVEGPLGWELRAQVPVQLPDGTGGFQVVRFVGV FT DGPRWFLRGVISGQGAVQPQAAGLLEQIFRDTVVVRGEGPMAPRDPIVLKLPNDAQMVP FT EGVQQEEGSRFAGGMGQLQRGPEITEVR" FT CDS 136493..137185 FT /transl_table=11 FT /gene="SCO5870" FT /gene_synonym="SC2E9.11" FT /product="ABC-transporter ATP binding protein" FT /note="SC2E9.11, probable ABC-transporter ATP binding FT protein, len: 230 aa; highly similar to many eg. Y796_METJA FT Q58206 hypothetical abc transporter atp-binding protein FT (235 aa), fasta scores; opt: 666 z-score: 870.6 E(): 0, FT 43.8% identity in 226 aa overlap. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop), PS00211 ABC FT transporters family signature and Pfam match to entry FT ABC_tran PF00005, ABC transporters, score 54.33" FT /db_xref="GOA:O54136" FT /db_xref="HSSP:1L2T" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:O54136" FT /protein_id="CAA16479.1" FT /translation="MTQVVTETMVRVEDVRKSYGRDSAAVHALRGVSFDVPRGELIALK FT GRSGSGKTTLLNIVGGLDTPDAGRVEVDGRDLAELDEDGLLALRRDRVGFVFQSFGLIP FT ILTAAENVGVPMRLRRAAAREREERVELLLSLVGLADHAAQRPGEMSGGQQQRVAIARA FT LANNPALLIADEPTGQLDAETGHSVMELLRAVVRSEQVTALVATHDATLLDLADRVLEL FT RDGEIVEE" FT misc_feature 136499..136927 FT /note="Pfam match to entry ABC_tran PF00005, ABC FT transporters, score 54.33" FT misc_feature 136628..136651 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 136940..136984 FT /note="PS00211 ABC transporters family signature" FT RBS 137313..137316 FT /note="possible RBS upstream of SC2E9.12" FT CDS 137319..139865 FT /transl_table=11 FT /gene="SCO5871" FT /gene_synonym="SC2E9.12" FT /gene_synonym="kdpD" FT /product="putative turgor pressure sensor" FT /note="SC2E9.12, kdpD, two-component sensor/protein kinase, FT len: 848 aa; similar to Escherichia coli turgor pressure FT sensor KDPD_ECOLI P21865 sensor protein kdpD (ec 2.7.3.-) FT (894 aa), fasta scores; opt: 997 z-score: 1347.4 E(): 0, FT 34.8% identity in 877 aa overlap. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop) and Pfam match to FT entry signal PF00512, Signal C terminal domain, score FT 184.57. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="GOA:O54137" FT /db_xref="HSSP:1JOY" FT /db_xref="InterPro:IPR006016" FT /db_xref="UniProtKB/TrEMBL:O54137" FT /protein_id="CAA16480.1" FT /translation="MGRGKLRIYLGAAPGVGKTYAMLSEAHRRVERGTDCVVALVEHHG FT RARTEVMLRGLEQVPRREAEYRGAAFTELDLDAVLARAPRVALVDELAHTNVPGVRNAK FT RWQDVEELLAAGIDVVSTVNIQHLESLGDVVESITGVRQRETVPDEVVRRADQIELVDM FT SPQALRRRMAHGNIYQSDKVDAALSNYFRPGNLTALRELALLWVADRADEYLQQYRSEH FT RVSKIWGSRERIVVGLTGGPEGRTLIRRAARLAEKGAGGEVLAVYIARSDGLTSASPKE FT LAVQRTLVEDLGGTFHHVLGEDIPAALLDFARGVNATQIVLGSSRRKAWQYVFGPGVGA FT TVARESGSDLDVHIVTHEEVAKGRGLPVARGARLGRSRIVWGWFAGLGGPVLLTLLLST FT VHLGLANDVLLYLALTVAAALLGGLYPALASAAVGSLLLNWYFTPPVNRITIADPRNML FT ALAIFVGVALSVASVVDVAARRTHQAARLRAESEILSFLAGDVLRGETSLETLLERVRE FT TFGMESAALLEREGDVAPWTCAGRAGSGPPVDRPEDADVDMPVGDHMALALTGRVLPAE FT DRRVLAAFAAQAAVVLDRRRLREEADRARTLAEGNRIRTALLAAVSHDLRTPLAGIKAA FT VTSLRSDDVAWSEEDRAELLEGIEEGADRLDHLVGNLLDMSRLQTGTVTPLIREIDVDE FT VAPMALGGVPEGSAELDIPETLPMVAVDAGLLERALANLVENAVKYSPDDRTVLVAASA FT LADRVEVRVVDRGPGVPDEAKDRIFEPFQRYGDAPRGAGVGLGLAVARGFAEAMGGTLN FT AEDTPGGGLTMVLTLRAVGSSAPTSRPATAERQAAL" FT misc_feature 137352..137375 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 138945..139562 FT /note="Pfam match to entry signal PF00512, Signal C FT terminal domain, score 184.57" FT CDS 139862..140545 FT /transl_table=11 FT /gene="SCO5872" FT /gene_synonym="SC2E9.13" FT /gene_synonym="kdpE" FT /product="putative turgor pressure regulator" FT /note="SC2E9.13, kdpE, two-component trascriptional FT regulator, len: 227, similar to E.coli turgor pressure FT regulator KDPE_ECOLI P21866 kdp operon transcriptional FT regulatory protein (225 aa), fasta scores; opt: 752 FT z-score: 1090.9 E(): 0, 51.1% identity in 225 aa overlap. FT Contains Pfam match to entry trans_reg_C PF00486, FT Transcriptional regulatory proteins, C terminal, score FT 96.22" FT /db_xref="GOA:O54138" FT /db_xref="HSSP:1KGS" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:O54138" FT /protein_id="CAA16481.1" FT /translation="MTRVLVIDDEPQIVRALVINLKARHYEVDAAHDGATALQLAAARH FT PDVVVLDLGLPDMDGVEVIRGLRGWTRVPILVLSARHSSDEKVEALDAGADDYVTKPFG FT MDELLARLRAAVRRAEPVPGGEDEVVVDTPEFTVDLAAKKVNRGGRDVRLTPTEWHLLE FT VLVRNTGRLVSQKQLLQEVWGPSYGTETNYLRVYMAQLRRKLEADPAHPRHFITEPGMG FT YRFEK" FT misc_feature 140069..140287 FT /note="Pfam match to entry trans_reg_C PF00486, FT Transcriptional regulatory proteins, C terminal, score FT 96.22" FT CDS 140542..141006 FT /transl_table=11 FT /gene="SCO5873" FT /gene_synonym="SC2E9.14" FT /product="hypothetical protein SC2E9.14" FT /note="SC2E9.14, unknown, len: 154 aa; similar to FT Mycobacterium tuberculosis hypothetical protein TR:O07196 FT (EMBL:Z96072) MTCY05A6.15C (122 aa), fasta scores; opt: 299 FT z-score: 502.1 E(): 9.1e-21, 41.0% identity in 117 aa FT overlap" FT /db_xref="GOA:O54139" FT /db_xref="InterPro:IPR004365" FT /db_xref="UniProtKB/TrEMBL:O54139" FT /protein_id="CAA16482.1" FT /translation="MSLAIPPRAGCMAVGVPRYASDMSAAPRSDKPVGRFRRMFDRLST FT SQEDLESEELREDADTAGCTRIGDCQDRQVVSVTGTLRTVTLRPRAGVPALEAELFDGS FT AALDVVWLGRRSIVGIEPGRKLIASGRISMSHGRRVLFNPKYELRPLGRE" FT RBS 141000..141003 FT /note="possible RBS upstream of SC2E9.15" FT CDS 141010..141828 FT /transl_table=11 FT /gene="SCO5874" FT /gene_synonym="SC2E9.15" FT /product="putative membrane protein" FT /note="SC2E9.15, putative membrane protein, len: 272 aa; FT similar to Mycobacterium tuberculosis hypothetical protein FT TR:O07195 (EMBL:Z96072) MTCY05A6.14C (223 aa), fasta FT scores; opt: 212 z-score: 285.5 E(): 1.1e-08, 23.5% FT identity in 247 aa overlap. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="InterPro:IPR016566" FT /db_xref="UniProtKB/TrEMBL:O54140" FT /protein_id="CAA16483.1" FT /translation="MTSLDKPTEETTEADDARAVTEAALFEAFGGVRGMIETVLPGLLF FT VTIFTLNNDLHMSAIAALAVSVVLVVVRLVMKDTVKHAFSGVFGVAFGVVFAMMTDNAK FT NFYLPGMLYTLGLALAYIVTSLAGVPLIGLILGPVFKENLSWRTRNPGRKKAYTKASYA FT WGLILLAKSAILFPLYWWADTEQLGWVLVTLKIPPFLLAVWLTWVFLAKAPAPIDVFAE FT MEAAEEAEKAEKAERERRERDQSEAGGALPGPSEADGEAADLRGGRHRKA" FT stem_loop 141834..141903 FT /note="hairpin loop with 31/33 bp stem" FT CDS complement(141947..142627) FT /transl_table=11 FT /gene="SCO5875" FT /gene_synonym="SC2E9.16c" FT /product="putative potassium uptake protein" FT /note="SC2E9.16c, possible potassium uptake protein; len: FT 226 aa; similar to many homologs of trkA eg. Mycobacterium FT tuberculosis TR:O07194 (EMBL:Z96072) MTCY05A6.13 (220 aa), FT fasta scores; opt: 870 z-score: 1486.1 E(): 0, 58.8% FT identity in 216 aa overlap. Also similar to upstream ORF FT SC2E9.17c, trkA, (E(): 1.8e-05, 22.6% identity in 212 aa FT overlap)" FT /db_xref="GOA:O54141" FT /db_xref="HSSP:1LSS" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:O54141" FT /protein_id="CAA16484.1" FT /translation="MRVAIAGAGAVGRSIAGELLENGHEVLLIDKAPTAISVERVPMAE FT WLLADACEITSLDEAALQRCNVVIAATGDDKVNLVVSLLAKTEYGVPRVVARVNNPKNE FT WLFNESWGVDVAVSTPRLMSALVEEAVSVGDLVRLLRFSHGDANLVELTLPEESALAGT FT QVGDVQWPEDTSLVTIIRGTRVLTPSREDSLEAGDELLFVAAQAREEQLEDLLSARRQP FT DGTL" FT CDS complement(142627..143298) FT /transl_table=11 FT /gene="SCO5876" FT /gene_synonym="trkA" FT /product="potassium uptake protein" FT /note="SC2E9.17c, trkA, potassium uptake protein, len: 223 FT aa; similar to first domain of TRKA_ECOLI P23868 Trk system FT potassium uptake protein (458 aa), fasta scores; opt: 249 FT z-score: 389.9 E(): 1.6e-14, 28.6% identity in 227 aa FT overlap. Also similar to downstream ORF SC2E9.16c (E(): FT 0.00062, 22.6% identity in 212 aa overlap)" FT /db_xref="GOA:Q53949" FT /db_xref="InterPro:IPR003148" FT /db_xref="UniProtKB/Swiss-Prot:Q53949" FT /protein_id="CAA16485.1" FT /translation="MHIVIMGCGRVGSALAQALEQQGHTVAVIDRDPTSFRRLGSSFGG FT RRVTGIGFDQDTLREAGIEEAGAFAAVSSGDNSNIIAARVAREMFGVENVAARIYDPRR FT AEVYQRLGIPTVATVRWTADQMLRRLLPSGAEPLWRDPTGGVQLAEVHTSSSWVGHKIS FT RLQEETGVRVAFVTRLGEAILPSSQTVLQEGDLVHVMMRTDEVHKVEAAFAKGPEEEGG FT H" FT RBS complement(142638..142643) FT /note="possible RBS upstream of SC2E9.16c" FT misc_feature complement(142750..144947) FT /note="99.9% match to EMBL:SCREDD M29790 S.coelicolor redD FT gene, complete cds from: 1 to: 2198" FT RBS complement(143312..143317) FT /note="possible RBS upstream of trkA" FT misc_feature 143338..143837 FT /note="identical to EMBL:SCREDDP X68944 S.coelicolor redD FT promoter region from: 241 to: 768" FT CDS 143566..144618 FT /transl_table=11 FT /gene="SCO5877" FT /gene_synonym="redD" FT /product="transcriptional regulator RedD" FT /note="SC2E9.18, redD, transcriptional regulator, len: 350 FT aa; identical to REDD_STRCO P16922 redd protein from FT Streptomyces coelicolor (350 aa). Possible alternative FT start site at 15238 (aa 84)" FT /db_xref="GOA:P16922" FT /db_xref="InterPro:IPR001867" FT /db_xref="UniProtKB/Swiss-Prot:P16922" FT /protein_id="CAA16486.1" FT /translation="MTGGGVLATMDPVRKLVRSQPKIGRHPVAAGQDGRDRHPIRSWEC FT GERARTARTGRTVGRAADPSDHGPSLYNFGGCVEINILGPVSIDTSHSGGGIRAGKVRT FT LVATLAIDAGRAVSLADLVDELWGATPPDNVLNALQAHAARARKVLNERACPERAGGIL FT RSVLGGYLLEIDPQCVDGNRFLRLVSQGAALLPADPTRAVELLETGLRLWRGPALIDAG FT EGRRCRGAAALFEERRLTALEDLISAMFLRGGEAQAIAMLQQLVAQYPLRERFCELLMV FT GLYRVGRQGDALESYRLARKRLDDELGVQPGALLRRRHAEILAQDPVLKVPSALWREPY FT APADTSLLSA" FT RBS 144656..144659 FT /note="possible RBS upstream of redX" FT CDS 144668..147616 FT /transl_table=11 FT /gene="SCO5878" FT /gene_synonym="redX" FT /product="polyketide synthase RedX" FT /note="SC2E9.19, redX, polyketide synthase with two FT beta-ketoacyl synthase domains, len: 982 aa; similar to FT many eg. ERY3_SACER Q03133 erythronolide synthase, modules FT 5 and 6 (3170 aa), fasta scores; opt: 649 z-score: 586.3 FT E(): 1.9e-25, 29.2% identity in 1029 aa overlap. Contains 2 FT x Pfam match to entry ketoacyl-synt PF00109, Beta-ketoacyl FT synthases, scores 52.40 and 310.80" FT /db_xref="GOA:O54142" FT /db_xref="InterPro:IPR014030" FT /db_xref="UniProtKB/TrEMBL:O54142" FT /protein_id="CAA16487.1" FT /translation="MSDNDTATATDTATDTPTATDTPTVTETDTASAARDPAEPIAIVG FT MSALYPGAQGVEDLWRLLLADGPAPASGTGPAPGGLGDIEVDVARFGIPPAQAASMARL FT QLLMVEAARQCLDDATGSGADRGRTDVVVGTCLGLDRQYANALRVDGARYARDLTEVLA FT DGAWRDTGIDARAAGQELNDALSRRLGASPHDRVGEMASTIPARIASAFKLRGRTLAVE FT SADATSYLALAHAVDNLRAGLAEAVLVVVGQRDEGRFARRALAAKGFAARPSEAGAGDA FT PVLTEGLGALLLKRRSTAERDGDRVYASVLDCALRHEARPGIFRYSLSAAHRRAAAEAA FT HRTADVAPGSVRLVECAGYGTAAVGRAEQEAIAGIHAGAPRDSVAVGTVRDRLGHTFAN FT AGLAGVTKAALALHHRTVPPVLPGTDPAPTTGPFRVPRAAEPWEPSTDGTPRRAAVLGA FT SLTGTVCHVLLEEAAPAGSVPQGAGADAHLGGARAAGAARRRFPGGQASAAGRETGAWQ FT AEPIAIVGFGGRFADSPDADGFWRTMLSGRDRIGPLPAELFDRDLYHAPGALALGRSYT FT DLGAPVPVPTQPPPGLRIPPHRYAATDAAQRLGLDVAAEMFARYGRDPHALDGVGTVVV FT GSNLGLSRERRLHTGLCLDDLEADVRSLAALAALGPDDVEAVTKLVRDRFGEAGPDDLP FT TTWDGCVASGIAALLGNEHGLDAVPVAVEAACASSLAAVDVAVGRLRSGGADYAVAGGV FT ELPCNARDMVLCSSLGLLSHSRITPFDAGADGFTPGDGCALFLLKRLTDARRDGDLVFG FT VLRAVGASNDAKSLIAPDADGQARAVRQAFAQVDFGPDEVDYLEAHGTGTRLGDRVEVA FT AAAQVYGTGRRTAPLDIGSAKSFLGHTFAAAGAAGLLRTLQALRQATLPPSVNLRELSP FT DLALDAVPARVATEAGPWPARAGRPRRAAVSAFGTGGINYHLLIEEGTDATR" FT misc_feature 144683..145849 FT /note="Pfam match to entry ketoacyl-synt PF00109, FT Beta-ketoacyl synthases, score 52.40" FT misc_feature 145988..147364 FT /note="Pfam match to entry ketoacyl-synt PF00109, FT Beta-ketoacyl synthases, score 310.80" FT misc_feature 147613..148506 FT /note="Pfam match to entry Acyl-CoA_dh PF00441, Acyl-CoA FT dehydrogenases, score 308.86" FT CDS 147613..148788 FT /transl_table=11 FT /gene="SCO5879" FT /gene_synonym="redW" FT /product="acyl-coa dehydrogenase RedW" FT /note="SC2E9.20, redW, acyl-coa dehydrogenase, len: 391; FT similar to many eg. ACDB_BACSU P45857 acyl-coa FT dehydrogenase (ec 1.3.99.-) (379 aa), fasta scores; opt: FT 831 z-score: 1005.0 E(): 0, 40.7% identity in 371 aa FT overlap. Contains Pfam match to entry Acyl-CoA_dh PF00441, FT Acyl-CoA dehydrogenases, score 308.86" FT /db_xref="GOA:O54143" FT /db_xref="HSSP:1JQI" FT /db_xref="InterPro:IPR006092" FT /db_xref="UniProtKB/TrEMBL:O54143" FT /protein_id="CAA16488.1" FT /translation="MNFDFDAGFDTETRELRDMVVRFARRELDSSGRFDDAEDFRRRWL FT LAGKQGLTGTTVPGEYGGSGLDAVSAAATMEALGYGCADTGFAFSVAAHLFAAVMPIVE FT FGTGEQRAAWLPALCSGERIAAHAITEPEAGSDALHLRTRARPVDDGHVLSGSKCFITN FT APVADVFVVQAATDPRGGFFGLTTFLVEASTPGLTVGRPYDKVGLRGSPTADVHFDDCY FT VPAGAVLGAEGSGASIFSSSMKWERTCLFAAYLGAMRRVLESTVDHVRDREQFGSPIGG FT FQAVSHRIVDMLGRYEGARLLLYRAARSLSDGTADEVGPALAKIAVSEAAVQLGLDAVQ FT LRGGLGIMDGEAETLLRDALPARIFSGTNEIQKNNVARALGLGRRRPAARR" FT RBS 148801..148804 FT /note="possible RBS upstream of redY" FT CDS 148814..149134 FT /transl_table=11 FT /gene="SCO5880" FT /gene_synonym="redY" FT /product="RedY protein" FT /note="SC2E9.21, redY, unknown function, len: 106" FT /db_xref="InterPro:IPR010916" FT /db_xref="UniProtKB/TrEMBL:O54144" FT /protein_id="CAA16489.1" FT /translation="MDVIIHRIRLHDGVDPARFEAWVRDVDYATCPRLPSVRAFAVHRV FT STEQDAPFHYFESISVTGPDEFSRDMKTEAFRDLVTVFDTMATVVEEMSGELLEPGYQA FT RP" FT misc_feature complement(149009..149409) FT /note="identical to EMBL:SCREDZ Y07902 S.coelicolor redZ FT gene from: 660 to: 1060" FT CDS complement(149206..149859) FT /transl_table=11 FT /gene="SCO5881" FT /gene_synonym="redZ" FT /product="response regulator" FT /note="SC2E9.22c, redZ, response regulator, partial CDS, FT len: >67 aa; identical to TR:P72402 (EMBL:Y07902) RedZ gene FT (217 aa). Contains probable helix-turn-helix motif at aa 12 FT to 33 (Score 1209, +3.30 SD)" FT /note="SC3F7.01c, redZ, response regulator, partial CDS, FT len >184 aa; identical to TR:P72402 (EMBL:Y07902) redZ gene FT (217 aa), and similar to many two-component regulators e.g. FT UVRY_ECOLI P07027 UvrY protein from Escherichia coli (218 FT aa), fasta scores; opt: 159 z-score: 291.2 E(): 5e-09, FT 26.3% identity in 186 aa overlap. Contains TTA leucine FT codon; a potential target for action of bldA, probable FT Helix-turn-helix motif at aa 162-183 (Score 1209, +3.30 SD) FT and Pfam match to entry response_reg PF00072, Response FT regulator receiver domain, score 31.36" FT /db_xref="GOA:P72402" FT /db_xref="HSSP:1FSE" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:P72402" FT /protein_id="CAD55237.1" FT /translation="MTTRVLVCCDRVILGEGIRALLERHDMKVQVETTQRGSLATAAET FT GPDILVGVAPLFTMDSIDKLTELARLGKTLLLTKPENTHRAFEALRVGVRAVLSAETSV FT EELVHVIRTITEVNAIIAPEEAQEALTRYWRSKAPKNLRPELTPRETEVLLLLTQGKTN FT TEMAATLSVSPTTVRSHVHRILRKLGAATRAQAVAIAYESGLLGICPGYGTPAR" FT misc_feature 149308..149409 FT /note="overlap with cosmid St3F7 from: 1 to: 102" FT misc_feature complement(149308..150068) FT /note="100% match to EM_BA:SCREDZ Y07902 S.coelicolor redZ FT gene from: 1 to: 761" FT misc_feature complement(149392..149394) FT /note="TTA leucine codon; potential target for action of FT bldA" FT misc_feature complement(149527..149850) FT /note="Pfam match to entry response_reg PF00072, Response FT regulator receiver domain, from 1 to 115, score 31.36" FT CDS complement(150123..151310) FT /transl_table=11 FT /gene="SCO5882" FT /gene_synonym="SC3F7.02c" FT /gene_synonym="redV" FT /product="RedV protein" FT /note="SC3F7.02c, redV, function unknown, len: 395 aa" FT /db_xref="UniProtKB/TrEMBL:O54145" FT /protein_id="CAA16173.1" FT /translation="MTTRRTDHMAAAVSTFAQALETAAGTAALSPSSHNCQPWGLGRAT FT STTARRSAADLTGADADEYLVLALDRERELTALAAHAVEMEVSCGVYWRILLRTLAAQG FT WTTAAVRVLDGDADPGAAGLPGGGRPFGAGWPTAWTPLCVVALRPGPLSGERPADLHES FT ALARRTHRGPYGREPVAPGLLRDLEEPATPGATAHPVHLRHLTERRDLRAFAAFVARHA FT GRDFGHRAAWRETHSFVRRDTADATARGDGFTLEQLFGPMSRPRRAAMRLALAPTTMHL FT LGKVGYHRVLAAGLADVVRRTPAVVTMGFAGQAPTRAEQLEGGARLADYWWRATRHGLS FT LHPISIVLQHDDLRGRLERELSLPGRTFFVSRVGVAGSPAPRSHRRADAAVHVSF" FT RBS complement(151317..151321) FT /note="possible RBS upstream of SC3F7.02c" FT CDS complement(151423..152208) FT /transl_table=11 FT /gene="SCO5883" FT /gene_synonym="SC3F7.03c" FT /gene_synonym="redU" FT /product="hypothetical protein SC3F7.03c" FT /note="SC3F7.03c, redU, unknown, len: 261 aa" FT /db_xref="GOA:O54146" FT /db_xref="InterPro:IPR008278" FT /db_xref="UniProtKB/TrEMBL:O54146" FT /protein_id="CAA16174.1" FT /translation="MREAVSLTDQVVLDASRPLWITHLRPDPRRLTLAVVSIARLRERG FT PHGLAALRARYLTAAETEQAATLRAPRRRLEWLAGRLALKHAVSAHGRRHWGLAREPRT FT VEVRAVSGGLQGGRPVVDAPVEVGLTHSGDFAVAVCGPHAVGVDLEHDRPMPPTLARLL FT DEECDPRAPSADARRLAAMPATLRWTCKEAVLKYYGFGLRIDAGEVALTGWLPDGRFTW FT RPGGGLLRHAPVAETRRPAGWAGVVAGHHLALVERPPGG" FT RBS complement(152211..152216) FT /note="possible RBS upstream of SC3F7.03c" FT CDS complement(152276..153166) FT /transl_table=11 FT /gene="SCO5884" FT /gene_synonym="SC3F7.04c" FT /product="hypothetical protein SC3F7.04c" FT /note="SC3F7.04c, unknown, len: 296 aa; some similarity to FT Archaeoglobus fulgidus hypothetical protein TR:G2648734 FT (EMBL:AE000977) AF1816 (300 aa), fasta scores; opt: 314 FT z-score: 322.6 E(): 8.9e-11, 30.2% identity in 301 aa FT overlap" FT /db_xref="UniProtKB/TrEMBL:O54147" FT /protein_id="CAA16175.1" FT /translation="MTFSIPADALDALEDEVVRALRTTDDRALTILGYGEVTLVLRLET FT DAGTFACKRLPVFPSRERLDRHSALVDDYVTRLDKGGVAVAETRMWHRRLPGGRAVAYC FT VQEALPEGRLCSRLLHTAGEAWCEGFFARFLDRVEATVTPRLGLDGQASNWIDVDGELV FT YLDVTTPLIRDERERELLDVPLFFTSLPWLVRDVVRMAMTKSIFDKFYTPRGVVLDFLG FT NLHKERLDHLVPRFLEQANARLDRPLDAEEVGAYYRDDARMWELIQRLRKADRFVHNKI FT LRRPYPFLLPRHVAR" FT CDS complement(153174..153614) FT /transl_table=11 FT /gene="SCO5885" FT /gene_synonym="SC3F7.05c" FT /product="putative membrane protein" FT /note="SC3F7.05c, putative membrane protein, len: 146 aa. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:O54148" FT /protein_id="CAA16176.1" FT /translation="MTGRNLILQRVVGALYILAGIGKFFPQLESVEGRLDDASEANDGT FT VISGPVDWLDRHPTGVMWFVAVAMVAAGLALLWNRRGLVIAALYGQLLMLVLFVVILVS FT SVPEILVMDAAFFAAAIYLLYRYHASPGARTAAPSGPTPEGR" FT RBS complement(153181..153184) FT /note="possible RBS upstream of SC3F7.04c" FT RBS complement(153625..153629) FT /note="possible RBS upstream of SC3F7.05c" FT CDS complement(153753..154976) FT /transl_table=11 FT /gene="SCO5886" FT /gene_synonym="SC3F7.06c" FT /gene_synonym="redR" FT /product="3-oxoacyl-[acyl-carrier-protein] synthase II" FT /note="SC3F7.06c, redR, probable FT 3-oxoacyl-[acyl-carrier-protein] synthase II, len: 407 aa; FT similar to many eg. FABF_ECOLI P39435 FT 3-oxoacyl-[acyl-carrier-protein] synthase II (EC 2.3.1.41) FT (beta-ketoacyl-acp synthase II) (412 aa), fasta scores; FT opt: 1054 z-score: 1061.9 E(): 0, 42.0% identity in 412 aa FT overlap. Also some similarity to SC3F7.12 from aa 800 to FT 1210 (E(): 3.3e-10, 32.2% identity in 432 aa overlap). FT Contains Pfam match to entry ketoacyl-synt PF00109, FT Beta-ketoacyl synthases, score 243.99" FT /db_xref="GOA:O54149" FT /db_xref="HSSP:1E5M" FT /db_xref="InterPro:IPR018201" FT /db_xref="UniProtKB/TrEMBL:O54149" FT /protein_id="CAA16177.1" FT /translation="MTDPSLAVTGLGLVTAAGMGVDATWEGVLRGRSAGARDERLAGLP FT VDIACAVPGLQPARHVDRRSVLIHDRFVQLAIVAAREAVADAGLDPLTWDGARVGVVVG FT CGLGGVTTWETQHRRLLERGPEAVSALLVPMLVPNMAAGHLAMDLRALGPNLVTATACA FT SGGTALGTAARLLRDGTCDIVVAGGTEAGVSPLMVTGFAQMGALSRRVDDPAAASRPFD FT ADRDGFVIGEGSGMLVLERAADAEARGATVRARLLGHGASADAHHVTAPDPEGAGALRA FT MEAALAQAGVTGRDIDHVNAHGTSTPLNDAVEAAVLGRLLGDRATVTSAKGVLGHTLGA FT AGAIEAALTVLSIERSTVPPTANLRRRDPAVDLDVVADAPREQKVELAMSNSFGFGGQN FT AVLVFASP" FT misc_feature complement(153759..154961) FT /note="Pfam match to entry ketoacyl-synt PF00109, FT Beta-ketoacyl synthases, from 1 to 442, score 243.99" FT CDS complement(154973..155218) FT /transl_table=11 FT /gene="SCO5887" FT /gene_synonym="SC3F7.07c" FT /gene_synonym="redQ" FT /product="acyl carrier protein" FT /note="SC3F7.07c, redQ, probable acyl carrier protein, len; FT 81 aa; similar to several eg. ACP_SYNY3 P20804 acyl carrier FT protein (acp) from Synechocystis (77 aa),fasta scores; opt: FT 153 z-score: 256.6 E(): 4.2e-07, 34.7% identity in 72 aa FT overlap" FT /db_xref="GOA:O54150" FT /db_xref="HSSP:2AF8" FT /db_xref="InterPro:IPR009081" FT /db_xref="UniProtKB/TrEMBL:O54150" FT /protein_id="CAA16178.1" FT /translation="MSTTYDKLVDLLVDGFAVDRAAIRPDVTFEELEMDSLFLVELLLV FT IQSEFGVKISDDAAVPTDTIAHAVALVDNEIAATAS" FT RBS complement(155228..155234) FT /note="possible RBS upstream of SC3F7.07c" FT RBS 155576..155581 FT /note="possible RBS upstream of SC3F7.08" FT CDS 155587..156594 FT /transl_table=11 FT /gene="SCO5888" FT /gene_synonym="SC3F7.08" FT /gene_synonym="redP" FT /product="3-oxoacyl-[acyl-carrier-protein] synthase" FT /note="SC3F7.08, redP, probable FT 3-oxoacyl-[acyl-carrier-protein] synthase III, len: 335 aa; FT similar to many eg. FABH_ECOLI P24249 FT 3-oxoacyl-[acyl-carrier-protein] synthase III (EC 2.3.1.41) FT (beta-ketoacyl-ACP synthase III) (317 aa), fasta scores; FT opt: 502 z-score: 881.2 E(): 0, 40.4% identity in 319 aa FT overlap" FT /db_xref="GOA:O54151" FT /db_xref="HSSP:1HNK" FT /db_xref="InterPro:IPR016038" FT /db_xref="UniProtKB/Swiss-Prot:O54151" FT /protein_id="CAA16179.1" FT /translation="MTRASVLTGLGSCLPSRCVTNAELERTMDTSDEWIRARTGIAQRY FT VAEEGTLTSDLAVGAAERALKSARLTPDEIDAVIVATTTPDRPCPATAPTVAARLGTGP FT VPAFDVSAVCSGFLYGLATGSGLIASGAAERVLVIGAETFSRILNPQDRSTSVIFGDGA FT GAVVLRAGEPGETGALGPLRLGSDGTGVDLITVPAGGPPRPGAAAPDDLADRYFTMEGK FT RVFWLAVQRMGECAESVLDRAGWRVADVDWLVSHQANHRITARLADEIGIPRERSVSNI FT AEVGNTAAASIPLALDHAHARGTLRPGDRVLLTAFGGGLTWGAAALTWPAVDPV" FT RBS 156644..156648 FT /note="possible RBS upstream of SC3F7.09" FT CDS 156654..156917 FT /transl_table=11 FT /gene="SCO5889" FT /gene_synonym="SC3F7.09" FT /gene_synonym="redO" FT /product="hypothetical protein SC3F7.09" FT /note="SC3F7.09, redO, unknown, len: 87 aa" FT /db_xref="GOA:O54152" FT /db_xref="UniProtKB/TrEMBL:O54152" FT /protein_id="CAA16180.1" FT /translation="MTPRKLITDYIADAWMGGDAEGLEPDTPIAELNIIDSAAIFDLVH FT YLQGEFRVTVPLPEVTLQNFRSVNAICALVDRLRQNEGGTAA" FT RBS 156898..156903 FT /note="possible RBS upstream of SC3F7.10" FT CDS 156914..158836 FT /transl_table=11 FT /gene="SCO5890" FT /gene_synonym="SC3F7.10" FT /gene_synonym="redN" FT /product="putative 8-amino-7-oxononanoate synthase" FT /note="SC3F7.10, redN, putative 8-amino-7-oxononanoate FT synthase, len: 640 aa; similar to many diverse transferases FT eg. BIOF_BACSH P22806 8-amino-7-oxononanoate synthase (389 FT aa), fasta scores; opt: 926 z-score: 888.4 E(): 0, 42.1% FT identity in 361 aa overlap. Also simlar to SC3F7.12 from aa FT 1700 to end (E(): 3.6e-15, 31.9% identity in 630 aa FT overlap). Contains Pfam match to entry aminotran_2 PF00222, FT Aminotransferases class-II, score 292.92 in C-terminus" FT /db_xref="GOA:O54153" FT /db_xref="HSSP:1FC4" FT /db_xref="InterPro:IPR009081" FT /db_xref="UniProtKB/TrEMBL:O54153" FT /protein_id="CAA16181.1" FT /translation="MTDSVDALPDTARIRERVVHVIAARTLYDESHLRPESHFEADLGI FT DSVIMESVLVSVREHFGLSAALPAGPTTIGELVDAVGAALAGTGDDRPAPAAGPLPAVP FT AEGTGDPVTEAVVAAAMRQTQYQRHQLGLDADLEGELGVDSVVLTSVVAEATERLGLTG FT AAPDAAGATTLRALADALRGLVAAAPGTAVPEAAPATGAAAPAPGRSGNAPAPGADGWD FT HRSMKDFTEQRDPDLFAKTRSFAGYLRSREKDRLYWYGMPLHSRCGSRAVIFDELEGRK FT REFLMFASNNYLGLANHPSVIEAVVDATRTYGATHTGSRFIGGTNMLHKELERRLAAFK FT QRPACIVYPGGYSANLGAISALVKSYDTLVVDRLNHMSIVDGARLSGAVRKIYRHNDMA FT DLERILSRSAAEGTGGRLIVADGVFSMHGDVCDLPEIVRLAKEYDARVMIDDAHATGVL FT GVRGSGTAEHFGLKGEVDLELGTMSKTLAGMGGFVVGEEEVVEYLRYYSNSYVFAANIP FT AGVAAGLIASIDVIESEPERLKRLWTNIGTLRDRLLDAGFDLEHSESAILPIVIGDERR FT AMELGRAVRARGLFCQTVVYPGVPLGDARLRVSVTCEHTPQDLELAAEIFVDAARETGV FT LPGTP" FT misc_feature 157883..158734 FT /note="Pfam match to entry aminotran_2 PF00222, FT Aminotransferases class-II, from 1 to 292, score 292.92" FT RBS 158929..158934 FT /note="possible RBS upstream of St3F7.11" FT CDS 158950..160548 FT /transl_table=11 FT /gene="SCO5891" FT /gene_synonym="St3F7.11" FT /gene_synonym="redM" FT /product="putative peptide synthase" FT /note="St3F7.11, redM, probable peptide synthase, len: 532 FT aa; similar to part of many peptide synthases eg. FT Myxococcus xanthus TR:Q50858 (EMBL:U24657) saframycin MX1 FT synthetase A (2605 aa), fasta scores; opt: 572 z-score: FT 782.6 E(): 0, 36.1% identity in 548 aa overlap. Contains FT PS00455 Putative AMP-binding domain signature and Pfam FT match to entry AMP-binding PF00501, AMP-binding enzymes, FT score 392.99. Also similar to part of SC3F7.12 aa 60 to 590 FT (E(): 2.8e-05, 25.3% identity in 561 aa overlap)" FT /db_xref="GOA:O54154" FT /db_xref="HSSP:1AMU" FT /db_xref="InterPro:IPR010071" FT /db_xref="UniProtKB/TrEMBL:O54154" FT /protein_id="CAA16182.1" FT /translation="MSAATPSVIRLPRDTSAQHAARPAFVGSDPLTYGEFTARVEAVAA FT RLLSLGTRTGDRIAVWMDKQPRYAEAIVAALEAGCAYVPLDGGQPVSRVRTILADAEPV FT VLFTDAHHAALLGDDDLPASVTTVVAVGDALPDTVGGIPVAPWESWEQGRAGRVTLLPS FT LTPGDLAALLYTSGSTGTPKGVQISHGALANFVAWARDELDVGPDDVFAGHASFNFDLS FT TFDLFTALSCGAAVWIVPDAATKDVTALAEGIRRHRITVWYSVPSVLHLLTTSAALTPE FT HAASLRYVLFAGEVFPVPQLRALRELLPPGTPLYNLYGPTETNVCTYHRVRPEDLHRAT FT PVPIGLPITGAGTTVVDDAGRTVREPGAIGELHVSGVCVTPGYWRRAEEPVSTAHCRGV FT HPTGDLVSYEEDGRLVYRGRKDRMVKLSGYRVELGEIEAAALRHPGIAEAAVLVDGSGP FT KARLRLYYTLCEGAERIGLVELKQHCARHLPTYMVPHGAVRLDRMPLNPNGKTDYRRLG FT LDAPPRPAAPLGTAR" FT misc_feature 159043..160302 FT /note="Pfam match to entry AMP-binding PF00501, AMP-binding FT enzymes, from 1 to 415, score 392.99" FT misc_feature 159463..159498 FT /note="PS00455 Putative AMP-binding domain signature" FT CDS 160549..167442 FT /transl_table=11 FT /gene="SCO5892" FT /gene_synonym="SC3F7.12" FT /gene_synonym="redL" FT /product="polyketide synthase" FT /note="SC3F7.12, redL, probable polyketide synthase, len: FT 2297 aa; contains 3 modules: N-terminus (start to approx. FT aa 700) similar to eg. N-terminus of TR:Q50857 FT (EMBL:U24657) saframycin mx1 synthetase B from Myxococcus FT xanthus (1770 aa) (fasta scores; E(): 0, 45.0% identity in FT 691 aa overlap), contains Pfam match to AMP-binding FT PF00501, AMP-binding enzymes, score 166.66; central module FT (approx aa 795 to 1800) similar to eg. TR:G2317861 FT (EMBL:U78289) Streptomyces fradiae tylactone synthase FT module 3 (1864 aa) (E(): 0, 39.9% identity in 1125 aa FT overlap), contains PS00606 Beta-ketoacyl synthases active FT site and Pfam match to ketoacyl-synt PF00109, Beta-ketoacyl FT synthases, score 585.24; and C-terminus (approx aa 1800 to FT end), similar to eg. TR:Q52936 (EMBL:X64131 FT acyl-transferase rkpG from Rhizobium meliloti (446 aa) FT (E(): 0. 44.9% identity in 394 aa overlap), contains FT PS00599 Aminotransferases class-II pyridoxal-phosphate FT attachment site and Pfam match to aminotran_2 PF00222, FT Aminotransferases class-II, score 276.93" FT /db_xref="GOA:O54155" FT /db_xref="HSSP:1FC4" FT /db_xref="InterPro:IPR018201" FT /db_xref="UniProtKB/TrEMBL:O54155" FT /protein_id="CAA16183.1" FT /translation="MARNRREKNVSHGPTDPLHEHWQGPEPETVTALLRHRAEHTPDAL FT AHRFLTDTDGTSVAWTYRELDLHAREVATHLRHAGVGQGPVLLLHPPGLDYLAAFFGCL FT YAGAVAVPAYPPDNARFGQTVPRLAAIARDCAATHALTTRRVRETVAADGTGRVGTELD FT GVRWLVTEDLYTGESTTAWEDPGATARSLAFLQYTSGSTAAPKGVMVEHGNLVRNLRSI FT HLRLGHDADSGMVSWLPPYHDMGLIGGILTPVYGGFPAHLMAPMTFVQRPLLWLETLSR FT TGASTSVAPNFGFEQCLRRITPAQRAGLDLSRWRLALNGAEPIRPDTLDRFAEYFAPAG FT FDRTALLPCYGLAEATLMVTGVRPADPPVVESFDAAALEAGTARPADPGGVRTTRVVGC FT GAPVADVEVAVVDAATGRRVPDGTVAEIRVSGPGVARGYWGRPEAAAEVFGTRIDGEPG FT NAWLRTGDVGFRHDGQLYVVGRTKDVIIVQGRNIHPQDVEQTAERVGAGLRAGYGAAFA FT VPTADGEQLALAYEIGGPGAGDPHALLARLRTAIADEHQVTPHTVVLLKRSSVPRTTSG FT KIQRGACRQRLLDLELPVVAASVVQDGALPDTPAPHAPASPDRTAALVADALDRAATDA FT PDGTSRYPRLLTAVRTLSERLGVALDVGELLSGPEPDGAPSLTGLCRAALADAAPAPTA FT APERTRTQAVDWLRRAVAARLGLRPSVIDTAVPFTSLGLDSKQAVALTAPFGDWLGTPV FT TPATLYDHPTVESLAAHVTGPEADGTPHPHPRRPAPEPARGRADEPVAVIGIGCRFPGA FT PDPDSYWRLLRDGRDAVGEAPADRHGDTGGRPGGFLEHVYDFDARFFGVSARETERMDP FT QQRLLLEVAWQTFEDAGIAPSSLAGTDTGVFVGISGHDYADLQMPHPDVVDMYSATGNA FT QSVAAGRLSYFFDLTGPSLALDTACSSSLAAVHTALRSLRDGECGVALAGGVNLMLTPG FT LSEALARGGMLGPGGRCRTFDDGADGYVRGEGAGLVCLKPLSAALADGDRVHAVLTGSA FT LGHGGRANGLTAPRSTAQRAVMTGALERAGVQPGQIDYVEAHGTGTALGDPIEWEALAG FT VYGRGRPADAPCPVGSVKTAIGHLEAAAGIAGLIKAVLVVREREVPPLLHLATPNRHLD FT WTGSGLTVPTTRRALPAGGTLRAGVSSFGFGGTNAHVIVESAPAPPAPAGESGAPDGTV FT HALSLSAHTESALATLAGRYRTHLAAHPGVPLAALCHSARTGRSRLPHRAVLTAATRDE FT LDTALEALIRREPAVDVARGGPADGTAPTVAFLFGGQGTQYPGMGRDLYDAHPVLARTL FT RRADAVLRGLGEIPLLDLLFDPDRAEDLARTRYCQPALVALEVALADLWTSCGVRPAAV FT LGHSVGALAAACVAGVLSLEDALTLAVVRGRAMDEQPGEGAMIACVGDPETVREIAAGH FT DRVALAAVNAPRNLVFSGAADRIAALRGDLERKGVTVRPLAVSHAFHSPLMAGAAEPLL FT EAARAVEFQPPAIPWISDATGEPVTRVDAEYWVRHLLGTVRFADGFARLRAGNAEGGLG FT CDAFVEIGPHPTLLNLGRSAVADGPEPDGRRTLWLPSLRRGAPGRRTLLRSLGGYQCAG FT GDIDWSALDDEHPPARVPLPHTPFERRTYRFQAPTPDQEGDPMPSQPTVPGTAPTGPAG FT EVSRTVLDTVARVCGFPVADLPVHARLGLELGFDSLMRTDLQRRLTDRFPQRMHTLQDL FT PEDPTVQDIIGRLAAGDDRDGDPAGGAHTARPALAGTGPAAPPAHPAAVPAAPPVPAPQ FT YAPYGAFPAPPHGYAVAAPVPQPGVPYPYPYGYPPHGAPGYAYYVPQPYPPQAFPPPAP FT PSPLQAAPAPVPAAAPAPVPDPVPAPAAPVRQERAFEDWAEYAELQGRLRQTRTSGSNP FT YGRTHEGFNSALATVDGTKVVNFAAFNYLALSHHPRVRQAAKDAVDRYGTSASATPLLF FT GETPLHHELEAEIARFIGTEAAIVFAGGHATNVATVGHLFGPEDLVVHDAWIHDSTVRG FT CILSGARRRSFPHNDWAALDRILTGARASHRRALVVIEGAYSQDGDIPDLPRFIEVKKR FT HGAMLMIDEAHSIGVLGRTGRGVGEHYGTDPADVDLWMGTLSKALGSLGGYIAARRPII FT EYLKFTAPLHIFSTGISPANAAAALEALRVVQDEPERVARVQELAEFFRAGARARGLDV FT GVSRLSAVIPVITGDWEKTMALSNSLLERGVNVMPIGYPAVPRDQCRLRFFINADHSEA FT DLEHSLDLLV" FT misc_feature 160729..162084 FT /note="Pfam match to entry AMP-binding PF00501, AMP-binding FT enzymes, from 1 to 415, score 166.66" FT misc_feature 162946..164175 FT /note="Pfam match to entry ketoacyl-synt PF00109, FT Beta-ketoacyl synthases, from 1 to 442, score 585.24" FT misc_feature 163384..163434 FT /note="PS00606 Beta-ketoacyl synthases active site" FT misc_feature 166525..167379 FT /note="Pfam match to entry aminotran_2 PF00222, FT Aminotransferases class-II, from 1 to 292, score 276.93" FT misc_feature 166996..167025 FT /note="PS00599 Aminotransferases class-II FT pyridoxal-phosphate attachment site" FT CDS 167446..168489 FT /transl_table=11 FT /gene="SCO5893" FT /gene_synonym="SC3F7.13" FT /gene_synonym="redK" FT /product="oxidoreductase" FT /note="SC3F7.13, redK, probable oxidoreductase, len: 347 FT aa; similar to many eukaryotic steroid dehydrogenases eg. FT TR:Q62878 (EMBL:L17138) 3 hydroxysteroid dehydrogenase from FT Rattus norvegicus (373 aa), fasta scores; opt: 103 z-score: FT 378.9 E(): 6.6e-14, 30.4% identity in 355 aa overlap; and FT to Mycobacterium tuberculosis putative dehydrogenase FT TR:O06373 (EMBL:Z95436) MTCY15C10.18 (314 aa), fasta FT scores; opt: 204 z-score: 417.9 E(): 4.4e-16, 27.7% FT identity in 339 aa overlap" FT /db_xref="GOA:O54156" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:O54156" FT /protein_id="CAA16184.1" FT /translation="MSSLSQDSPSAAAPDILVTGASGFIGGHLVHRLAERGHRVRVLAR FT STSDRAAFAGAAAQVTVGDLGDTDSLRRATTGIRHVYNCAGLSADWGPWDRFRAVNVDG FT ARNLVEAAHEAGTVERLVHLSTTDVYGYPERPCDERTAPRDIGLPYNRSKMLGEAAVWA FT AAERTGQPVTVVRPVSVYGPGSKDFVIEIANLLLGKQMVYIRGGRVPAGLLYVSNAVDG FT IIAAATGEHTAGRAYNLRDPHDTTWREYVEALAEGLGVKAPWLSLPTPVATAVATVSEK FT LWGALRIDSRPVLTRHAVHLFDRDQSYPIGRAQEELGFKGEVDFQEGMRRTVAWLDSPE FT GRAHVAR" FT RBS 168464..168468 FT /note="possible RBS upstream of SC3F7.14" FT CDS 168476..169318 FT /transl_table=11 FT /gene="SCO5894" FT /gene_synonym="SC3F7.14" FT /gene_synonym="redJ" FT /product="thioesterase" FT /note="SC3F7.14, redJ, probable thioesterase, len: 280 aa; FT similar to many e.g. TR:Q00442 (EMBL:X60379) erythomycin A FT biosynthesis thioesterase (EC 3.1.-.-.) from FT Saccharopolyspora erythraea (Streptomyces erythraeus) (247 FT aa), fasta scores; opt: 451 z-score: 472.9 E(): 3.8e-19, FT 38.0% identity in 237 aa overlap" FT /db_xref="GOA:O54157" FT /db_xref="InterPro:IPR001031" FT /db_xref="UniProtKB/TrEMBL:O54157" FT /protein_id="CAA16185.1" FT /translation="MSPADLLSQRSAWFPRPVAAPAAEPPDPAAAPLRLVCFPYAGGTV FT SAFRGWQERLGDEVAVVPVQLPGRGLRLRERPYDTMEPLAEAVADALEEHRLTHDYALF FT GHSMGALLAYEVACVLRRRGAPRPRHLFVSGSRAPHLYGDRADHTLSDTALREVIRDLG FT GLDDADTLGAAYFDRRLPVLRADLRACERYDWHPRPPLDCPTTAFSAAADPIATPEMVE FT AWRPYTTGSFLRRHLPGNHFFLNGGPSRDRLLAHLGTELDALGTTPHRKATREATWTF" FT RBS 169295..169299 FT /note="possible RBS upstream of SC3F7.15" FT CDS 169306..170394 FT /transl_table=11 FT /gene="SCO5895" FT /gene_synonym="SC3F7.15" FT /gene_synonym="redI" FT /product="putative methyltransferase" FT /note="SC3F7.15, redI, possible methyltransferase, len: 362 FT aa; weakly similar to several e.g. Streptomyces griseus FT TR:P72450 (EMBL:X95596) methyltransferase (242 aa), fasta FT scores; opt: 130 z-score: 204.9 E(): 0.00032, 27.6% FT identity in 192 aa overlap" FT /db_xref="GOA:O54158" FT /db_xref="InterPro:IPR000780" FT /db_xref="UniProtKB/TrEMBL:O54158" FT /protein_id="CAA16186.1" FT /translation="MDILSLAKSVGSRVEAPLTDLRTVTKVLGNPHMPLLLALSKGFVE FT PVYRAAFLASAASSGVLAALAVRPCDLESLAERLDIDDEDLPRLKEWLDMGIRLGDLGK FT REGCYKLRSLPAKALAQPGNDAIAAALEEVLRFHVPALLNGPRMLREGRRFSLDDQDGL FT VIARSTRVIQPLVEEAIARTLDRNAPVRLLEVGCGSGTYVRYAAELNPRLSALAVDLQQ FT DVADSAAANMAEWGLTDRVETRQADLRTLDAQPQFDLVTLHNNIYYFPEAERVEALRRA FT HDLLAPGGRLLLTTSCKGGNVGLEALNLWFTYADFGGPLPQADALADQLRQAGFDDVEA FT TRIVPGEQFHAFTGTSKRVAHA" FT RBS 170401..170405 FT /note="possible RBS upstream of SC3F7.16" FT CDS 170417..173218 FT /transl_table=11 FT /gene="SCO5896" FT /gene_synonym="SC10A5.01" FT /gene_synonym="SC3F7.16" FT /gene_synonym="redH" FT /product="phosphoenolpyruvate-utilizing enzyme" FT /note="SC10A5.01, redH, probable FT phosphoenolpyruvate-utilizing enzyme, partial CDS, len: >95 FT aa; overlaps and extends ORF from neighbouring cosmid FT SC3F7.16; similar to many eg. PPSA_STAMA P46893 probable FT phosphoenolpyruvate synthase (834 aa), fasta scores; opt: FT 215 z-score: 351.4 E(): 2.3e-12, 47.8% identity in 69 aa FT overlap" FT /note="SC3F7.16, probable phosphoenolpyruvate-utilizing FT enzyme, partial CDS, len: >872 aa; similar to many eg. FT PPSA_STAMA P46893 probable phosphoenolpyruvate synthase FT from Staphylothermus marinus (834 aa), fasta scores; opt: FT 392 z-score: 614.9 E(): 4.7e-27, 33.0% identity in 309 aa FT overlap. Contains Pfam match to entry PEP-utilizers FT PF00391, PEP-utilizing enzymes, score 23.96" FT /db_xref="GOA:Q8CJQ2" FT /db_xref="HSSP:1H6Z" FT /db_xref="InterPro:IPR002192" FT /db_xref="UniProtKB/TrEMBL:Q8CJQ2" FT /protein_id="CAD55238.1" FT /translation="MDTHVSDTTTPAGAGEGPAGPVTDPAGHAACVVTLGAGGPTGGHR FT GELGGKGTRLAELSAAGLPVPPAFCLTTALFDAYLRETGIAAEAAGADPRTLRERILGT FT RMPASIADAVLDAYGSMGRPRVAVRSSGLREDSAAQSFAGQHDTVLDVCGDEDVLDAVL FT RCWASLWSDRATVYRDTDAPDALAVVVQEMIHTDVSGVMFTVDPVNPRPHRLVVEACQG FT LGEGLVSGQVSSDFFVVDDEKLEVVEERVRYKVTKCAPLEPGRIGMTKVDAAARSVPCL FT THDQLRELGALAVRIRDLYGSEQDIEWGVRDGVFHLFQTRPITTRPAAPAAPSGALSPY FT VAPQPEPVLNGTLWSRMDIGEIFVGLMTPLGLSFARYYQRNVHTDCAGALGVRDTGEAD FT LHMGFYQGHVYLNISYSSYLLAQCLPTRDQRHFTSRFVSEEVDLADYENPFGTFPGGME FT DLLSTVHWLQHTAREMTQMKSRSQQMVDARLYEFDRARGLDLTRMSRRELHGELHRDLA FT WFHDMHIGYMPYYINAFAFYGLLTELCARWLGSDGVGLQNRVKTDMSSLRTVESAKEVW FT SVAQAAKNDPAVLRIIKDEPLEDIARLLREDPAGQRFWDRHMEPFLRANGTRGHQEMEI FT THPRWIDDPSYIFQMIRRYVADGFSIDDILRRSSGWSDDSREVLGRLPMPKRQVLDTVI FT SLYALCSELRETTRMSMITSIWLVRNVVYEVGRRLVADGVLHSPDEIAHLDFEDVRRYL FT AGDEDAVRVFDRARIDAARRLHEHNKRLPEPPLTFVGVHDITASVRPAADGARLEGLAA FT SPGRIVGRARIVEDLVWQADEFEAGEILVTGYTDASWTPLFAIAGGVVTDIGSMLSHSS FT IVAREFHVPSVVNTKDATQRINTGDLIVVDGDAGTVEVVESADTDPQGPAGAAGTPAGA FT TTD" FT misc_feature complement(172930..173037) FT /note="overlap with Cosmid St10A5" FT misc_feature 172930..173037 FT /note="overlap with St3F7 from: 23623 to: 23730" FT misc_feature 172931..173032 FT /note="Pfam match to entry PEP-utilizers PF00391, FT PEP-utilizing enzymes, from 1 to 36, score 23.96" FT RBS 173284..173287 FT /note="possible RBS upstream of SC10A5.02" FT CDS 173296..174483 FT /transl_table=11 FT /gene="SCO5897" FT /gene_synonym="SC10A5.02" FT /gene_synonym="redG" FT /product="putative oxidase" FT /note="SC10A5.02, redG, probable oxidase, len: 395 aa; FT similar in N- terminus to many diverse oxidases e.g. FT TR:P95483 (EMBL:U7449 3) aminopyrrolnitrin oxidase PrnD FT from Pseudomonas fluorescens (363 aa), fasta scores; opt: FT 349 z-score: 372.1 E(): 1. 6e-13, 33.3% identity in 165 aa FT overlap" FT /db_xref="GOA:O54095" FT /db_xref="InterPro:IPR017941" FT /db_xref="UniProtKB/TrEMBL:O54095" FT /protein_id="CAA16434.1" FT /translation="MIPNQWYPIVEAQEVGNDKPLGVRRMGQDLVLWRDIDGNLVCQGA FT RCPHKGANLGDGRMKGNTIECPYHGFRYGADGACRVIPAMGSEARIPGSLRVPTYPVRE FT QFGLVWMWWGDERPTADLPPVAAPAEVTDNRKLYATKRWTRPVHYTRYIESLLEFYHVT FT YVHRDHWFNYIDYLLLYGTPSKFGLDGRERYLAATRITNHRVETEAEGQTIRYSFDHCQ FT EDDPTNTTHYVITFTFPCMVHVQTEQFETTSWLVPIDDQNTEHILRWYEYEQVKPVLRF FT EPLRRLLPWASLYMEKWVQDPQDVRIMEHQEPKISAGGVNKFIPVDEMNAKYISMRAKL FT IADASAAPSSPARAAEPEPEAAGRGGSAARATGNGRGAAGGRRGTKPKEDAAARP" FT CDS 174526..175206 FT /transl_table=11 FT /gene="SCO5898" FT /gene_synonym="SC10A5.03" FT /gene_synonym="redF" FT /product="probable membrane protein" FT /note="SC10A5.03, redF, probable membrane protein, len: 226 FT aa. Contains possibe hydrophobic membrane spanning regions" FT /db_xref="GOA:O54096" FT /db_xref="InterPro:IPR001104" FT /db_xref="UniProtKB/TrEMBL:O54096" FT /protein_id="CAA16435.1" FT /translation="MYGGYDASTGPKALVTAFNTVAVAGAVWFLFGGADTVADWFGTDF FT DEAVTLRRVLLATLSVLYLLRFIATNFVMLQRKMEWSESATIGIWVLVIHGTMAYFGGT FT NDAGVSAFTWLGVVLYLLGSYLNTGSEYQRKLWKKRPENKGKLYTEGLFKHSMHINYFG FT DAVLFSGFALVTGTPWAFAIPLIMVCMFVFLNIPMLDKYLAERYGEAFDEYASRTAKFV FT PYVY" FT RBS 175362..175365 FT /note="possible RBS upstream of SC10A5.04" FT CDS 175371..176258 FT /transl_table=11 FT /gene="SCO5899" FT /gene_synonym="SC10A5.04" FT /product="hypothetical protein" FT /note="SC10A5.04, unknown, len: 295 aa; similar to FT hypothetical proteins from Mycobacterioum tuberculosis and FT M. leprae e.g. YV29_MYCTU Q11167 hypothetical 39.3 kd FT protein CY20G9.29 (358 aa), fasta scores; opt: 1075 FT z-score: 1514.7 E(): 0, 57.8% identity in 263 aa overlap" FT /db_xref="GOA:O54097" FT /db_xref="InterPro:IPR002123" FT /db_xref="UniProtKB/TrEMBL:O54097" FT /protein_id="CAA16436.1" FT /translation="MTGDIPFGEAEASLTAEVLREVLAGGAEAFARLTSDEGAVDDFGF FT DPELTDDYLLPALRLLYEKYFRVDLEGLENVPAEGGALLVANHSGTLPLDALMLQVALH FT DHHSTHRRLRLLAADLAFDLPVVRDLARKAGHVRACPENALRLLGSGELVGVMPEGYKG FT LGKPFEERYRLQRFGRGGFAAVALRSRRPMVPCSIVGAEEIYPMIGSAPTLARMLKLPY FT FPITPTFPLLGALGLIPMPTKWTIRFGAPIHTDGFPEDAAEDPLVVEKLAGEVKDTIQH FT TLNEMLEGRGSPFV" FT CDS 176627..178702 FT /transl_table=11 FT /gene="SCO5900" FT /gene_synonym="SC10A5.05" FT /product="probable membrane protein" FT /note="SC10A5.05, probable membrane protein, len: 691; high FT ly similar to M. tuberculosis putative membrane protein TR: FT O07192 (EMBL:Z96072) MTCY05A6.11C (647 aa), fasta scores; o FT pt: 1980 z-score: 3557.6 E(): 0, 62.7% identity in 659 aa o FT verlap and weakly similar to many transport proteins eg. PR FT OY_SALTY P37460 proline-specific permease proy from Salmone FT lla typhimurium (456 aa), fasta scores; opt: 169 z-score: 1 FT 82.8 E(): 0.0055, 24.2% identity in 355 aa overlap" FT /db_xref="UniProtKB/TrEMBL:O54098" FT /protein_id="CAA16437.1" FT /translation="MSKLTDVPKRILIGRALRSDRLGETLLPKRIALPVFASDPLSSVA FT YAPGEVLLVLSIAGVSAYHFSPWIAVAVVVLMFTVVASYRQNVHAYPSGGGDYEVATTN FT LGPKAGLTVASALLVDYVLTVAVSISSGIENLGSAIPFVVEHKVLCAVAVILLLTLMNL FT RGVRESGTLFAIPTYVFVAGVFIMIVWGAFRGLVLDDTMRAPTADYEIKPEHGGLAGFA FT LIFLLLRAFSSGCAALTGVEAISNGVPAFRKPKSKNAGNTLAMMGLLAVTMFCGIIALA FT AATDVRMSENPATDLFHNGVAVGADYVQHPVISQVAEAVFGEGSFLFIVLAAATALVLF FT LAANTAYNGFPLLGSILAQDRYLPRQLHTRGDRLAFSNGIVLLAGAAMLLVVVYGADST FT RLIQLYIVGVFVSFTLSQIGMVRHWNRNLAGERDQSKRRHMMRSRAINAFGAFFTGLVL FT VVVLATKFTHGAWVALLGMCIFFATMTAIRKHYDRVAEEIAAPEDPEEAQSDDMVRPSR FT VHSVVLISKIHRPTLRALAYAKLMRSDSLEALSVNVDPAETKALREEWERRGIAVPLKV FT LDSPYREITRPVIEYVKSLRKESPRDAVSVIIPEYVVGHWYEHLLHNQSALRLKGRLLF FT TPGVMVTSVPYQLESSEAARRRARKRQDWSAPGAVRRGPAHHHQDRDRTKDSSSST" FT RBS 178741..178744 FT /note="possible RBS upstream of SC10A5.06" FT CDS 178755..180131 FT /transl_table=11 FT /gene="SCO5901" FT /gene_synonym="SC10A5.06" FT /product="putative RNA methyltransferase" FT /note="SC10A5.06, unknown, len: 458; similar to M. FT tuberculosis hypothetical protein TR:O07191 (EMBL:Z96072) FT MTCY05A6. 10C (405 aa), fasta scores; opt: 455 z-score: FT 878.5 E(): 0, 38.4% identity in 417 aa overlap, and weakly FT similar to several putative RNA methyltransferases eg. FT YGCA_ECOLI P5513 5 hypothetical RNA methyltransferase (433 FT aa), fasta scores ; opt: 358 z-score: 331.2 E(): 3e-11, FT 27.4% identity in 441 aa overlap" FT /db_xref="GOA:O54099" FT /db_xref="InterPro:IPR002792" FT /db_xref="UniProtKB/Swiss-Prot:O54099" FT /protein_id="CAA16438.1" FT /translation="MQAEPKKSQAEQRAVAEPVSEPVSLVGEEYEVEVGPVAHGGHCIA FT RTSEGQVLFVRHTLPGERVVARVTEGEEGARFLRADAVEILDPSKDRIEAPCPFAGPGR FT CGGCDWQHAKPGAQRRLKGEVVAEQLQRLAGLTPEEAGWDGTVMPAEGDKLPAGQVPSW FT RTRVQFAVDADGRAGLRRHRSHEIEPIDHCMIAAEGVSELGIERRDWPGMATVEAIAAT FT GSQDRQVILTPRPGARLPIVELDRPVSVMRVGEKDGGVHRVHGRPFVRERADDRTYRVG FT SGGFWQVHPKAADTLVTAVMQGLLPRKGDMALDLYCGVGLFAGALADRVGDQGAVLGIE FT SGKRAVEDARHNLAAFDRVRIEQGKVESVLPRTGIDEVDLIVLDPPRAGAGRKTVQHLS FT TLGARRIAYVACDPAALARDLGYFQDGGYRVRTLRVFDLFPMTAHVECVAILEPAAKGL FT " FT stem_loop 180662..180716 FT /note="hairpin loop with 21 bp stem" FT CDS 180741..180851 FT /pseudo FT /transl_table=11 FT /gene="SCO5902" FT /gene_synonym="SC10A5.07" FT /note="SC10A5.07, probable transposase pseudogene fragment, FT len: 36 aa; highly similar to part of many insertion eleme FT nt transposases eg. Q50761 (EMBL:X65618) TRANSPOSASE (308 a FT a), fasta scores; opt: 125 z-score: 284.8 E(): 1.2e-08, 46. FT 9% identity in 32 aa overlap" FT /db_xref="PSEUDO:CAD55239.1" FT RBS 180832..180838 FT /note="possible RBS upstream of SC10A5.08" FT CDS 180848..181225 FT /pseudo FT /transl_table=11 FT /gene="SCO5903" FT /gene_synonym="SC10A5.08" FT /note="SC10A5.08, questionable ORF, possible pseudogene FT fragment, len: 125; contains segment of strong similarity FT to part of S. coelicolor regulator TR:Q53894 (EMBL:U51332) FT AbsA2 (222 aa), fasta scores; opt: 110 z-score: 210.7 E(): FT 0.00 016, 47.1% identity in 70 aa overlap" FT /db_xref="PSEUDO:CAD55240.1" FT CDS complement(181494..181874) FT /transl_table=11 FT /gene="SCO5904" FT /gene_synonym="SC10A5.09c" FT /product="conserved hypothetical protein" FT /note="SC10A5.09c, unknown, len: 126 aa; similar to Mycobac FT terium tuberculosis hypothetical protein TR:O06156 (EMBL:Z9 FT 5555) MTCY06F7.02C (105 aa), fasta scores; opt: 125 z-score FT : 213.5 E(): 0.00011, 37.7% identity in 69 aa overlap" FT /db_xref="GOA:O54100" FT /db_xref="InterPro:IPR007138" FT /db_xref="UniProtKB/TrEMBL:O54100" FT /protein_id="CAA16441.1" FT /translation="MHIIAIAVRAPAGRDSHRHHTNNREKTEMSTAVTEFTVAAPAQGA FT FENNCTASMRATLSNVPGLRNARLLRPRKGAHGYLAVLNFEDDAAFTAYTSSEAFRAAH FT ADPTHSLSDDNRVTVFEAVTQG" FT CDS complement(181909..184452) FT /transl_table=11 FT /gene="SCO5905" FT /gene_synonym="SC10A5.10c" FT /product="probable export protein" FT /note="SC10A5.10c, probable export protein, len: 847 aa; FT similar to eg. S. coelicolor actinorhodin antibiotic export FT protein TR:Q53902 (EMBL:M64683) ORF2 (ACTII) (711 aa), FT fasta scores; opt: 705 z-score: 1126.2 E(): 0, 35.4% FT identity in 746 aa overlap" FT /db_xref="GOA:O54101" FT /db_xref="InterPro:IPR000731" FT /db_xref="UniProtKB/Swiss-Prot:O54101" FT /protein_id="CAA16442.1" FT /translation="MNSPALLRCLLGSKKRAAVVVAFWVLIAGLLAGVAPALESVEDNA FT SANLPPAASDSMKARDLVRAQLPGQDATPAIIVVRGKGTDAAKSATQSVAAITSALSGT FT SRPDHVVSVVSTVTAPDAAAELVSQDRGAQLVIVPMEGSPSDESFQNAVDEVRALASDR FT AGPADVAVTGPAGIATDTVKVFSGGDKVLLLATVVLVLIILLAIYRSPLMALVPLLAVG FT VAMRVAETLGAILADAGVITVSSQTASIMTVLLFGVGTDYALIITARYRETLLDEPDRA FT RAMQAAVRRTAESVLASASTIVLAMFALLVAVSPALHGFGPYLALGVAVMALVAFTFIP FT ALVLLLGRSVFWPGGVDKAAERSRGAGIWHRIAALVARAPVKVASAVIALLVVLSAGLL FT GYQESFNTLSGFRAATESEHGQHLIREEFGPGEIAPSTVVVHSQDNLRSSPAPADIATA FT LTDADHVSRVADPRMGKDGKTVFYDVILDLDPYSSKALDAIGPLKQATQSAAQAAGVQD FT ATVLIGGETAQNADIRSALDRDTTLIVLLVLAIVTVVLVLLLRSLLAPLYLVATLLLSF FT LATLGATTFFTVTVLGDDGIGNRVTAYIFVFLVALGVDYNIFIMSRFKQELRTQPPAKA FT ITAALTRTGGVISSAGLILAATFAVLMTQPIRELFQFGFAMACGILLDTFLIRPLLVPA FT IVRLLGNRALWPARPGTPQTPSTPTSEPPSADAPAARAAETGTSRLLRAFTWIAIIEAC FT TWAGLLAGMYLKYIPETTELGVRIFGTLHGAAFIVYVSLTVLVAIRLKWRLGRTTIFAL FT LAAVPPFMTIAFEIWARRTGRLPQPTADPSPTPAL" FT RBS 184599..184602 FT /note="possible RBS upstream of SC10A5.11" FT CDS 184606..185202 FT /transl_table=11 FT /gene="SCO5906" FT /gene_synonym="SC10A5.11" FT /product="probable transcriptional regulator" FT /note="SC10A5.11, probable transcriptional regulator, len: FT 198 aa; similar to many members of the tetR family eg. FT TR:P72569 (EMBL:U58281) TetR homologue WhiR from FT Streptomyces roseosporus (179 aa), fasta scores; opt: 367 FT z-score: 569.5 E(): 1.6e-24, 38.3% identity in 175 aa FT overlap. Contains pr obable helix-turn-helix motif at aa 37 FT to 58 (Score 1635, +4.76SD)" FT /db_xref="GOA:O54102" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:O54102" FT /protein_id="CAA16443.1" FT /translation="MPKIEAGSVREHRAQRLAQLIDAAEELLEEGGAEALTAGAVAARA FT GIARNSIYRYFNSIDDLLELVVTREFPAWIDAVEQAIAAETTPAAQAAAYVRANLEQAA FT RGTHGWRAALTRDSLSPSARERVRNLHISLHEALARVVRELGQPQPELTVAVVQAVVDA FT CIRRIDQGDDLTTVSDFAAGATRRLLADDDLPHHP" FT CDS complement(185317..185436) FT /transl_table=11 FT /gene="SCO5907" FT /gene_synonym="SC10A5.12c" FT /product="hypothetical protein" FT /note="SC10A5.12c, unknown, len: 39 aa" FT /db_xref="UniProtKB/TrEMBL:O54103" FT /protein_id="CAA16444.1" FT /translation="MTNERTTNVNALNALVRVVDVVIDGRRALTGRPPGGKIG" FT RBS complement(185441..185444) FT /note="possible RBS upstream of SC10A5.12c" FT CDS 185517..185711 FT /transl_table=11 FT /gene="SCO5908" FT /gene_synonym="SC10A5.13" FT /product="hypothetical protein" FT /note="SC10A5.13, unknown, len: 64 aa" FT /db_xref="UniProtKB/TrEMBL:O54104" FT /protein_id="CAA16445.1" FT /translation="MAMTLRLPDDLDTKLTERARGEGCSKQELAIGAIRDARDRAELKV FT DDVLAGLMDSDAEILDYLK" FT CDS 185708..185914 FT /transl_table=11 FT /gene="SCO5909" FT /gene_synonym="SC10A5.14" FT /product="hypothetical protein" FT /note="SC10A5.14, unknown, len: 68 aa" FT /db_xref="UniProtKB/TrEMBL:O54105" FT /protein_id="CAA16446.1" FT /translation="MSGVRYLQIDEILAIVRTVNGAEHSVRDMGLLVSAIERPRTNVFG FT AELYPTLHEKPRHYCTPSPAITR" FT CDS 185947..186291 FT /transl_table=11 FT /gene="SCO5910" FT /gene_synonym="SC10A5.15" FT /product="putative membrane protein" FT /note="SC10A5.15, putative membrane protein, len: 114 aa. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:O54106" FT /protein_id="CAA16447.1" FT /translation="MRVFLRFNGASASTVPPHGRRPDGPEARHALLTSSPLLSSALGPA FT LLIALSALGVLALDTALWVSVVSEVAAPARWGFVGGLRVGAGRLGALIAGVLNAVIGLG FT VVAVKLIAGH" FT CDS complement(186426..187991) FT /transl_table=11 FT /gene="SCO5911" FT /gene_synonym="SC10A5.16c" FT /product="possible oligopeptide binding protein" FT /note="SC10A5.16c, possible oligopeptide binding protein, FT len: 521; weak similarity to many eg. OPPA_SALTY P06202 FT periplasmic oligopeptide-binding protein (542 aa), fasta FT scores; opt: 343 z-score: 306.2 E(): 7.4e-10, 25.0% i FT dentity in 537 aa overlap. Contains N-terminal signal seque FT nce" FT /db_xref="GOA:O54107" FT /db_xref="InterPro:IPR000914" FT /db_xref="UniProtKB/TrEMBL:O54107" FT /protein_id="CAA16448.1" FT /translation="MRPIRAHIRASVITPTVIATALAAGLLLYPTDDQEGTTIKVGTTE FT PPTSLDPAGGYDSGSTTLYSNVFQTLLTLEPGVAEPVPDAAESCSFTDSGLRTYRCRLR FT DDITFSSGRRMTAKDVRFSFERVKKIDSDVGPSSLLDTIESMDARDRTVTFRLTAPDAT FT FPFKLTTGAGSIVDSTTYPADSLRSDGRIDGTGPYGVVSYAKGEKISLSPNPRYKGAAE FT NTGRPIELHFYDTPDSLARAWISHRIDVALRQLPPEMLADLNPSDPGLRVTEAQSAETR FT NLYLNNRRGKPFHDRRARQAAAWLIDRDRISYDVYDGTVDPLYSLIPTSITGHTTSFFD FT NYPHKDAEKARRLLVEAGEEIPLSFTYGYAAGRGSAHEEAAEVKKQLEADGLFKVTLRG FT YEWDEFQKSWAEGELDAYAVGWVADYPDPDTFGGPLVGTDGTMATGYGSKAADRLITSS FT QRFADRSDAEADLEALQRIVARDVPVVPLWQAKDFVVSGEDVGGGQYAVDGTGLLRLWR FT LTWI" FT RBS complement(188000..188003) FT /note="possible RBS upstream of SC10A5.16c" FT RBS 188429..188433 FT /note="possible RBS upstream of SC10A5.17" FT CDS 188438..191035 FT /transl_table=11 FT /gene="SCO5912" FT /gene_synonym="SC10A5.17" FT /product="probable secreted protease" FT /note="SC10A5.17, probable secreted protease, len: 865 aa; FT similar to many members of the peptidase family M9 (zinc me FT talloprotease) eg. COLA_VIBAL P43154 microbial collagenase FT precursor from VIBRIO ALGINOLYTICUS (814 aa), fasta scores; FT opt: 1357 z-score: 1196.6 E(): 0, 36.0% identity in 773 aa FT overlap. Contains N-terminal signal sequence and PS00142 N FT eutral zinc metallopeptidases, zinc-binding region signatur FT e" FT /db_xref="GOA:O54108" FT /db_xref="InterPro:IPR000601" FT /db_xref="UniProtKB/TrEMBL:O54108" FT /protein_id="CAA16449.1" FT /translation="MRKSLVRRGLGAALPLALTVAMSVGLLSQPAGAAGNTGSVVHVAA FT DDPEHAGPPPVAQSPTAETEHVAQGRTRASELPPVAASKDALKEVYGKTAKAPVRPSKS FT TDKAVAGKTGNSRARAAACNVSDFTSRSGGALVQQIKASTTDCVNTLFNLTGNDAYYAF FT RESQMTSVAYALRDGSTSYPGNASTGMPQLVLYLRAGYYVHYYNAGTVGTYGSSLQTAI FT RAGIDAFFASPHSRDVNDANGETLAEAVTLIDSAEENARYIHVVKRLLADYDSTWNSSW FT WMLNAVNNVYTVTFRGHQVPAFVSAVQSDPGLIDALYNFASGHLALLGTDQSYLTSNAG FT RELGRFLQHSALRSKVSPLAGGLLNSSSIKGRTAPLWVGVAEMTDYYDKANCSYYGTCD FT LQAQLARSVLTVTYPCSSSITIKAQQMTSGELSSSCSSLRNQDAYFHNVVRDNGPVAND FT NNSTIEVVVFDSSTDYQTYAGAMYGIDTNNGGMYLEGNPSAAGNQPRFIAYEAEWLRPD FT FQIWNLNHEYTHYLDGRFDMYGDFNANITTPTIWWVEGFAEYVSYSYRGVPYTEATTEA FT GRRTYALSTLFDTTYSHDTTRIYRWGYLAVRYMLENHRADMDTVLSHYRAGNWNAARSY FT LTGTIGTRYDNDWYTWLAACAAGNCGGGGTNPPGNQAPTAAFTTAVQGLNVTFTDQSTD FT ADGTIASRSWSFGDGTTSTATNPVKTYGSAGSYTVKLTVTDDKGATATATRTVTVGSGG FT GGGTECNGTDTRELGQNCQRGNQSATTGNYAYLYLYVPAGTTQLKITTSGGTGDADLYY FT STSGWPGTTSYTQRATGAGNNHTLTITNPPAGANYISLHAVSSFSGVTVSSAY" FT misc_feature 190001..190030 FT /note="PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature" FT RBS 191188..191193 FT /note="possible RBS upstream of SC10A5.18" FT CDS 191200..192435 FT /transl_table=11 FT /gene="SCO5913" FT /gene_synonym="SC10A5.18" FT /product="probable secreted protease" FT /note="SC10A5.18, probable secreted protease, len: 411 aa; FT similar to many members of the peptidase family S2A eg. PRT FT C_STRGR P52320 serine protease c precursor (ec 3.4.21.-) (4 FT 57 aa), fasta scores; opt: 326 z-score: 460.9 E(): 1.8e-18, FT 29.8% identity in 420 aa overlap. Contains N-terminal sign FT al sequence and PS00134 Serine proteases, trypsin family, h FT istidine active site. Also contains TTA leucine codon, a po FT tential target for action of bldA" FT /db_xref="GOA:O54109" FT /db_xref="HSSP:1HPG" FT /db_xref="InterPro:IPR018114" FT /db_xref="UniProtKB/TrEMBL:O54109" FT /protein_id="CAA16450.1" FT /translation="MKSLPARRRRRAMWSLIMSVGLTCALATPAVGSGDQGTSRLSASQ FT QAAAGQLAADQHISTQEAQRRVLRQERLTGVATALRERLGSRFAGAWIDQKHGGRLTVA FT VTRSTATALVEARSAQAQAPDTTTVVVDRSLRQLDRMSAGLAHRIAAANKGAAHGLQSA FT VVVQDNKVRLDLPRGKTLTPAQHAVVEWAKRTLGDGLEVSTYAHASEPFYCGGQYSCDP FT PLRSGLAIYGTNVRCSSAFMAYSGSSYYMMTAGHCAEDSSYWEVPTYSYGYQGVGHVAD FT YTFGYYGDSAIVRVDDPGFWQPRGWVYPSTRITNWDYDYVGQYVCKQGSTTGYTCGQIT FT ETNATVSYPGRTLTGMTWSTACDAPGDSGSGVYDGSTAHGILSGGPNSGCGMIHEPISR FT ALADRGVTLLAG" FT misc_feature 191209..191211 FT /note="TTA leucine codon; potential target for action of FT bldA" FT misc_feature 191953..191970 FT /note="PS00134 Serine proteases, trypsin family, histidine FT active site" FT CDS complement(192608..193600) FT /transl_table=11 FT /gene="SCO5914" FT /gene_synonym="SC10A5.19c" FT /product="probable transcriptional regulator" FT /note="SC10A5.19c, probable transcriptional regulator, len: FT 330 aa; similar to many membres of the LysR family e.g. MPR FT R_STRCO P43160 small neutral protease regulatory protein FT (316 aa), fasta cores; opt: 510 z-score: 581.6 E(): FT 3.4e-25, 35.8% identity in 324 aa overlap. Contains PS00044 FT Bacterial regulatory proteins, lysR family signature" FT /db_xref="GOA:O54110" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:O54110" FT /protein_id="CAA16451.1" FT /translation="MELELRHLRVLCAIADAGGVGRAAAALGYTQPAMSTQLRRIEGLL FT GEGVFLRSSAGVELTAYGAQVVGRAREILALSDNLARLRPPRSSGATRRLRLGAINTPV FT VPTLLDVLREACPDLTVSVSSVYATGELIDLLEAGELDVALGCDYPGLPLRHSPKLDHR FT AIRTVPVFVATPADHPLAHRLEVSLADLSEDAWFVSADDGVGWPGAFYDACGAAGFRPA FT VTHEFHMLDQLQSMIAKGLGVAAVQPTMRPVGGVLVKPLAGDPLWQRHLLVWRRDSVEA FT SAVEVVHHHAVRAHWQLLSQAPHFQKWVTRAYAPARPTNGAGKALPGTV" FT misc_feature complement(193454..193546) FT /note="PS00044 Bacterial regulatory proteins, lysR family s FT ignature" FT RBS complement(193607..193611) FT /note="possible RBS upstream of SC10A5.19c" FT RBS 193831..193835 FT /note="possible RBS upstream of SC10A5.20" FT CDS 193843..194358 FT /transl_table=11 FT /gene="SCO5915" FT /gene_synonym="SC10A5.20" FT /product="conserved hypothetical protein" FT /note="SC10A5.20, unknown, len: 171 aa; weak similarity to FT part of TR:P79078 (EMBL:Y10421) DELTA-9 FATTY ACID DESATURA FT SE (EC 1.14.99.5) from CRYPTOCOCCUS CURVATUS (555 aa), fast FT a scores; opt: 83 z-score: 221.8 E(): 3.7e-05, 25.1% identi FT ty in 171 aa overlap" FT /db_xref="GOA:O54111" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:O54111" FT /protein_id="CAA16452.1" FT /translation="MPHTCISFTVEATGAAVHRARHRVSTALSWWGGPVEEELRFSAEL FT VTSELLTNGLRHAGGPMTVELTLVHDMVVVAVLDDSRELPRPRQTEADDECGRGLALIE FT DLSLIRGVETTSRGKRCWAVLPLRTPQERAIESAPAEEADHGFEADRERWSLAPQGSGL FT LASLFPAM" FT CDS 194675..195187 FT /transl_table=11 FT /gene="SCO5916" FT /gene_synonym="SC10A5.21" FT /product="hypothetical protein" FT /note="SC10A5.21, unknown, len: 170 aa; contains probable FT helix-turn-helix motif at aa 90 to 111 (Score 1413, +4.00 FT SD)" FT /db_xref="UniProtKB/TrEMBL:O54112" FT /protein_id="CAA16453.1" FT /translation="MGCLRFSGCERALGRLSRDAVRSAPWGPQDDPVSDRWHLWKNLCD FT KALAEVRSHSACWTTANTPRPVGVHEQTTRERWHQLHDLLGKGVGLLECARRLNLSLNT FT VKRYPRTRDPEALRPVKQLFREVQEQGCTGSFTLLYRSTQGRAEGDRPVGGSRLDAHRI FT HHWNGDV" FT RBS 195956..195960 FT /note="possible RBS upstream of SC10A5.22" FT CDS 195965..196303 FT /transl_table=11 FT /gene="SCO5917" FT /gene_synonym="SC10A5.22" FT /product="conserved hypothetical protein" FT /note="SC10A5.22, unknown, len: 112 aa; weakly similar to S FT . coelicolor HSPR_STRCO P40183 putative heat shock protein FT hspr (151 aa), fasta scores; opt: 153 z-score: 212.0 E(): 0 FT .00013, 31.7% identity in 101 aa overlap" FT /db_xref="GOA:O54113" FT /db_xref="InterPro:IPR000551" FT /db_xref="UniProtKB/TrEMBL:O54113" FT /protein_id="CAA16454.1" FT /translation="MTADDSYGRLDDDDYPAYTMGRAAEMLGTTPAFLRAVGEARLITP FT LRSEGGHRRYSRYQLRIAARARELVDQGTPVEAACRIVILEDQLQEARRINEELQRRPA FT GLVDKAEG" FT CDS complement(197961..198272) FT /transl_table=11 FT /gene="SCO5918" FT /gene_synonym="SC10A5.23c" FT /product="hypothetical protein" FT /note="SC10A5.23c, unknown, len: 103 aa" FT /db_xref="UniProtKB/TrEMBL:O54114" FT /protein_id="CAA16455.1" FT /translation="MRCVIARFPFDLTKSGVLESMKGVKPEPVTGESVIIGRRHYPAKQ FT VGQVITRQDRRDFSTGEILRAMAQLGFTCRTLPEAAPARSDSPLQRASAMLGAPHLSV" FT RBS complement(198277..198280) FT /note="possible RBS upstream of SC10A5.23c" FT CDS complement(198321..198725) FT /transl_table=11 FT /gene="SCO5919" FT /gene_synonym="SC10A5.24c" FT /product="hypothetical protein" FT /note="SC10A5.24c, unknown, len: 134 aa" FT /db_xref="InterPro:IPR000644" FT /db_xref="UniProtKB/TrEMBL:O54115" FT /protein_id="CAA16456.1" FT /translation="MTPGQLQDRSVGALPLRGTVADVMDAAGPQVWYDMTVEVALSVMA FT AARAEHLVVCDEDARCVGLVTQARLTAVRDSSRYTDRLRLGDITDDSEPFVSPSATREE FT AEDAVPFGRLGLVPVVDEHGSALGVLALSR" FT RBS complement(198732..198737) FT /note="possible RBS upstream of SC10A5.24c" FT CDS complement(198772..200268) FT /transl_table=11 FT /gene="SCO5920" FT /gene_synonym="SC10A5.25c" FT /product="probable DEAD-box RNA helicase" FT /note="SC10A5.25c, probable DEAD-box RNA helicase, len: 498 FT aa; similar to many e.g. RHLE_ECOLI P25888 putative FT ATP-dependent RNA helicase RhlE (454 aa), fasta scores; FT opt: 845 z -score: 770.8 E(): 0, 36.2% identity in 434 aa FT overlap. Con tains possible DEAD-box at aa 221-224 (1 FT mismatch to prosit e consensus), 2x PS00017 ATP/GTP-binding FT site motif A (P-lo op) and PS00135 Serine proteases, FT trypsin family, serine ac tive site, though the last may be FT spurious. Also contains P fam match to entry helicase_C FT PF00271, Helicases conserved C-terminal domain, score FT 108.77 and Pfam match to entry DEA D PF00270, DEAD and DEAH FT box helicases, score 236.10" FT /db_xref="GOA:O54116" FT /db_xref="HSSP:1QDE" FT /db_xref="InterPro:IPR018114" FT /db_xref="UniProtKB/TrEMBL:O54116" FT /protein_id="CAA16457.1" FT /translation="MNRTRTNDRFARTRHGGADSGKGGSRFGSPAPRRPAGPSRSGGYG FT RRPGAVQGEFALPRTITPALPAAEGFADLDMPGELLAALGQQGVTVPFPIQAATLPNSL FT AGRDIMGRGRTGSGKTLAFGLALLARTAGRRAEPRQPLGLVLVPTRELAQQVTDALTPY FT ARSVKLRLATVVGGMSIGRQASALRGGAEVVVATPGRLKDLIDRGDCRLNQVSVTVLDE FT ADQMADMGFMPQVTALLDQVRPEGQRMLFSATLDRNVDLLVRRYLSDPVVHSVDPSAGA FT VTTMEHHVLHVHGADKHAATTEIAARDGRVIMFLDTKHAVDRLTRDLLNSGVRAAALHG FT GKSQPQRTRTLAQFKTGHVTVLVATNVAARGIHVDNLDLVVNVDPPTDHKDYLHRGGRT FT ARAGESGSVVTLVTPNQRRGMVRLMSEAGIRPQTTQVSPGDEALSRITGAQAPTGIPVV FT ITAPATERPKKRGATSRGRRRPASATRRTPALKSTAGAAA" FT misc_feature complement(199039..199074) FT /note="PS00135 Serine proteases, trypsin family, serine act FT ive site" FT misc_feature complement(199240..199263) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(199300..199545) FT /note="Pfam match to entry helicase_C PF00271, Helicases co FT nserved C-terminal domain, score 108.77" FT misc_feature complement(199591..200268) FT /note="Pfam match to entry DEAD PF00270, DEAD and DEAH box FT helicases, score 236.10" FT misc_feature complement(199909..199932) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(200278..200281) FT /note="possible RBS upstream of SC10A5.25c" FT stem_loop 200555..200598 FT /note="hairpin loop with 19/20 bp stem" FT CDS complement(200617..200820) FT /transl_table=11 FT /gene="SCO5921" FT /gene_synonym="scoF5" FT /gene_synonym="SC10A5.26c" FT /product="cold-shock domain protein" FT /note="SC10A5.26c, scoF5, cold-shock domain protein, len: FT 67 aa; highly similar to many e.g. CSPF_STRCO P48859 cold FT shock protein ScoF from S. coelicolor (67 aa), fasta FT scores; opt: 383 z-score: 750.4 E(): 0, 82.1% identity in FT 67 aa overlap. Contains PS00352 'Cold-shock' DNA-binding FT domain signature" FT /db_xref="GOA:O54117" FT /db_xref="HSSP:1MJC" FT /db_xref="InterPro:IPR019844" FT /db_xref="UniProtKB/TrEMBL:O54117" FT /protein_id="CAA16458.1" FT /translation="MAAGTVKWFNAEKGFGFIEQDGGGADVFAHYSNIAAQGFRELLEG FT QKVNFDIAQGQKGPTAENIVPA" FT misc_feature complement(200719..200778) FT /note="PS00352 'Cold-shock' DNA-binding domain signature" FT RBS complement(200828..200833) FT /note="possible RBS upstream of SC10A5.26c" FT CDS complement(201462..202442) FT /transl_table=11 FT /gene="SCO5922" FT /gene_synonym="SC10A5.27c" FT /product="possible oxidoreductase" FT /note="SC10A5.27c, possible oxidoreductase, len: 326 aa; FT some similarity to many members of the SHORT-CHAIN FT DEHYDROGENASES/REDUCTASES FAMILY (SDR) eg. YGFF_ECOLI FT P52037 hypothet ical oxidoreductase (247 aa), fasta scores; FT opt: 96 z-score : 310.6 E(): 4.2e-10, 29.1% identity in 213 FT aa overlap. Con tains PS00017 ATP/GTP-binding site motif A FT (P-loop)" FT /db_xref="GOA:O54118" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:O54118" FT /protein_id="CAA16459.1" FT /translation="MSNEDITRQTTENTEQAGPKGPLAGRIALVAGATRGAGRAQAVEL FT GRAGATVYVTGRTTRARASEVGRTTETIEETAELVTAAGGTGIAVPTDHLDEAQVRALV FT ERIDREYERLDILVNDLWGGEHLLATSVFGKKSWETPLADGLRILELGARSHVITAALL FT LPLLIRSDAPLHVEVTDGTAHSNRRYRENIYYDLAKNAPIRLAFGLAQELAEYEGTAVA FT VSPGFLRSEQMLSHFGVSEENWRDAIAQEPTFAIAESPHYLARTVAALAADPDRAKRWN FT GKSTSSGELARAYGVTDVDGSRPDAWAYFEDVTYGGKEASPDDYR" FT misc_feature complement(201591..201614) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(203065..204150) FT /transl_table=11 FT /gene="SCO5923" FT /gene_synonym="SC10A5.28c" FT /product="ABC-transporter ATP-binding protein" FT /note="SC10A5.28c, ABC-transporter ATP-binding protein, len FT : 361 aa; similar to many eg. Streptomyces reticuli TR:P964 FT 83 (EMBL:Y08921) MSIK PROTEIN involved in in cellobiose and FT maltose transport(377 aa), opt: 809 z-score: 1069.1 E(): 0 FT , 40.4% identity in 381 aa overlap. Contains PS00017 ATP/GT FT P-binding site motif A (P-loop). PS00211 ABC transporters f FT amily signature and Pfam match to entry ABC_tran PF00005, A FT BC transporters, score 35.90" FT /db_xref="GOA:O54119" FT /db_xref="HSSP:1G29" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:O54119" FT /protein_id="CAA16460.1" FT /translation="MPELVVENIKKSFHGTAVLEDVNFTVADGEFFTLLGPSGCGKSTT FT LSCVAGLETPDSGTIRVGDQVFFDGTRRSTVPPEGRNLGLVFQSYALWPHMTVADNLAL FT PLKLRKVTKGEQRRLIDDVLTKVDMAHLRDRYPHQLSGGQQQRVALARGIVYSPGVLLL FT DEPLSNLDAKMRDQARVWLKDLQREVGITTVYVTHDQVEAMSLSDRIAVFMHGHLQQVG FT TPTEIYETPATPEVAGFIGRCNLLEGRVGATEGGAVQVELGETGQRLRVAGACSAGSSA FT TVGLRSERITLTDRADAPHDGAVNVLRARIEQCSYTGARFEYELSIGDVRVHAESPVRH FT TDGEINLIIRPDDCLLFPAQV" FT misc_feature complement(203689..203733) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(203743..204150) FT /note="Pfam match to entry ABC_tran PF00005, ABC transporte FT rs, score 35.90" FT misc_feature complement(204022..204045) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(204143..205912) FT /transl_table=11 FT /gene="SCO5924" FT /gene_synonym="SC10A5.29c" FT /product="probable integral membrane protein" FT /note="SC10A5.29c, probable integral membrane protein, len: FT 589 aa; similar to many permeases eg. TR:Q44123 (EMBL:U050 FT 42) iron utilisation protein AFUB from Actinobacillus pleur FT opneumoniae (687 aa), fasta scores; opt: 564 z-score: 426.3 FT E(): 1.5e-16, 25.0% identity in 547 aa overlap" FT /db_xref="GOA:O54120" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:O54120" FT /protein_id="CAA16461.1" FT /translation="MAIQTPPAPPAPSRIPRAGELGTPQYRRLFGAGREVTIHWLTFLV FT TAVLVLAPVVPILYQSVRNQPLYAAGGAFTLSNYTHLFTSAGFGSIVLDTLLFAVLTTV FT FALAIAVPMAILLERTRFPAARLFGQVLRWPIYISPLVLAFGWIVVYGPAGFLTGAVRE FT GFGWVPWNLYSLPGMAFVEAVAQVPIAYLFCANALAASDTSLENAARSVGAGPLRVLRS FT VVVPMLRPPMLYAGLLIFGTAIETLSIPLILGEPAGITLFSNFLYEQGIDSINPDYGLL FT GAASTFMLLTTIALVVFQTRLLGHAQRFVSVRGKATRSDLLDIGAWKWLGFAFVGLYVV FT FGALLPMLALILRAFTSLLTPLVNPFDLLTLDNFRLIFDYAPYTESIVNSITVAFVGAV FT AVTLFGTVVVLVARRSDFRFARLLETTAQSPHAVPGLIVGIGLFWAFTWIPGGDAVRGT FT LFALIIAFGIRALPSAYGAISPATMQLGAELDNAARVAGADWWRTVSRIMLRLLVPAML FT ASFLLIWTQMIREYAPAMFLAGAESQVIGTTAIDLWTQGETGSVAALATLQIAVTAVVA FT GLAGLLLKGKKHA" FT RBS complement(204160..204163) FT /note="possible RBS upstream of SC10A5.28c" FT RBS complement(205918..205921) FT /note="possible RBS upstream of SC10A5.29c" FT CDS complement(205967..206218) FT /transl_table=11 FT /gene="SCO5925" FT /gene_synonym="SC10A5.30c" FT /product="hypothetical protein" FT /note="SC10A5.30c, unknown, len: 83 aa" FT /db_xref="GOA:O54121" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:O54121" FT /protein_id="CAA16462.1" FT /translation="MKTAPHPNAARLFLDFLLSAEGQAAVAEGGLVPYRPDVRQDAMDS FT LQDMRRRLGADRVHLYRPVRVPERVREAYVARWEKAAG" FT CDS complement(206215..206736) FT /transl_table=11 FT /gene="SCO5926" FT /gene_synonym="SC10A5.31c" FT /product="conserved hypothetical protein" FT /note="SC10A5.31c, unknown, len: 173 aa; highly similar to FT the C-terminus of many prokaryotic and eukaryotic aconitase FT s eg. ACO1_ECOLI P25516 aconitate hydratase 1 (ec 4.2.1.3) FT (890 aa), fasta scores; opt: 422 z-score: 567.1 E(): 2.2e-2 FT 4, 49.3% identity in 138 aa overlap" FT /db_xref="GOA:O54122" FT /db_xref="HSSP:1AMJ" FT /db_xref="InterPro:IPR015937" FT /db_xref="UniProtKB/TrEMBL:O54122" FT /protein_id="CAA16463.1" FT /translation="MGPVHEAAATYRAAGHDLVVVAGRNYGAGSSRDWAAKAQALLGVR FT AVIAESFERIHRNNLIGMGVLPLEFEEGDTASAHAFTGEEEFTFDGLADLCVGTNPVAL FT SLVRPDAPRATVRLRLRLHSRQELAYLRHGGILPYVMASRYPPPSTAGDCWGGATTRRA FT PSSCRARCPS" FT CDS complement(206872..207093) FT /transl_table=11 FT /gene="SCO5927" FT /gene_synonym="SC10A5.32c" FT /product="hypothetical protein" FT /note="SC10A5.32c, unknown, len: 73" FT /db_xref="UniProtKB/TrEMBL:O54123" FT /protein_id="CAA16464.1" FT /translation="MWHQVGRSSGAAGVGGDDVDDGARRRVGDLISQAEREGDPEQAAR FT STVSSGSGGGGVRVIGSHRGRRCCRGRS" FT RBS complement(207104..207107) FT /note="possible RBS upstream of SC10A5.32c" FT CDS complement(207282..207986) FT /transl_table=11 FT /gene="SCO5928" FT /gene_synonym="SC10A5.33c" FT /product="hypothetical protein" FT /note="SC10A5.33c, unknown, len: 234 aa" FT /db_xref="GOA:O54124" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:O54124" FT /protein_id="CAA16465.1" FT /translation="MMNDDDPALDDPVGQSLSGRHAHLARRFGRAATYLTDVATFSSVS FT VDPDAEDWADLAGLLGPGAFADMFSSPAVPPPGWEPVFSLEGRQMTWPGDGRPGRTRSA FT SDTDVVELGADSVPEMLDLAARTEPGPFWPRTHELGTYLGVRVDGTLVAMAGERLRPPG FT WTEISAVCAAPEARGQGYAARLVRALTERISARGDRPFLHVAEANTGAIALYERLGFKT FT RRPVTFRGFRTP" FT RBS complement(207996..208000) FT /note="possible RBS upstream of SC10A5.33c" FT CDS complement(208455..209231) FT /transl_table=11 FT /gene="SCO5929" FT /gene_synonym="SC10A5.34c" FT /product="possible oxidoreductase" FT /note="SC10A5.34c, possible oxidoreductase, len: 258 aa; FT very weakly similar to many eg. TR:G2673979 (EMBL:U94980) FT 2,4 -DIENOYL-COA REDUCTASE (HUMAN) (335 aa), fasta scores; FT opt: 167 z-score: 231.2 E(): 1.1e-05, 21.2% identity in 208 FT aa overlap. Contains PS01070 DNA/RNA non-specific FT endonucleases active site" FT /db_xref="GOA:O54125" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:O54125" FT /protein_id="CAA16466.1" FT /translation="MHGTTRSTKRRLGNDTMRWDNHRVVITAAGRDFGRTLAIRLADLG FT AEVFLSARRLAAAQRVRDEIRDRGHQRVHAFACDLTDPASIRDFASGVAEHTDRVDVLV FT NNGSRYLTGPDLLSATDADVVDTIASGATGTVLTTRSFLPLLLNSDTPDVVTMVSACGT FT PGHHRSDAHDAFYAAKSAQAGFTEILSKRLRAQGVRVISLYPPDFDNADPLSEEWATTS FT REAEDALTAQSLVECILFAVAQPRDCFIKAFHFEQV" FT misc_feature complement(209007..209033) FT /note="PS01070 DNA/RNA non-specific endonucleases active si FT te" FT CDS 209298..210377 FT /transl_table=11 FT /gene="SCO5930" FT /gene_synonym="SC10A5.35" FT /product="possible NTP pyrophosphohydrolase" FT /note="SC10A5.35, possible NTP pyrophosphohydrolase, len: 3 FT 59 aa; similar to TR:Q53738 (EMBL:X92429) NTP FT pyrophosphohydrolase PUR7 from S. alboniger (152 aa), fasta FT scores; opt: 467 z-score: 614.5 E(): 5e-27, 54.8% identity FT in 135 aa overlap. Contains PS00893 mutT domain signature" FT /db_xref="GOA:O54126" FT /db_xref="InterPro:IPR020084" FT /db_xref="UniProtKB/TrEMBL:O54126" FT /protein_id="CAA16467.1" FT /translation="MPNPGADEVWTVGAVILNREGRAFAQKRSRDRRLFPGAWDIVGGH FT VEEGETLLEALAREVEEETGWRLTRVRRFLGTTTWTGDDGGGLRHEADYLVEVDGDLDH FT PRLEWSKHSAYDWFGPGDLTRLKENRGPGEYLIHDLIAGAVADSPFDLLRADALTSPDR FT LRELYPQPNPNSLRKETDRLTEETRALIGCSSLVFIGSADREGRADVTPRGGPAGFVSV FT LDEQTLVIPDATGNKRLDTLHNVLETGRLGLLFLVPGRPTTLRINGRACVSARPELLAR FT LTPVGKPPVTALVVQVEQVYPHCPKSLMRADAWRPEQWMPADAQPSSAEVTLAQLNLPG FT LTLDRIEDAERESLRLRYE" FT misc_feature 209427..209486 FT /note="PS00893 mutT domain signature" FT CDS complement(210512..211945) FT /transl_table=11 FT /gene="SCO5931" FT /gene_synonym="xlnA" FT /gene_synonym="SC10A5.36c" FT /product="xylanase A" FT /note="SC10A5.36c, xlnA, xylanase A precursor, partial CDS, FT len >383 aa; overlaps and extends ORF from neighbouring FT cosmid SC7H1.01c; almost identical to XYNA_STRLI P26514 FT endo- 1,4-beta-xylanase a precursor (477 aa) (99.2% FT identity in 383 aa overlap). Conatains PS00591 Glycosyl FT hydrolases famil y 10 active site and Pfam match to entry FT glycosyl_hydro3 PF 00331, Glycosyl hydrolases family 10, FT score 183.41. Also si milar in part to S. coelicolor FT SC7H1.02, abfB, arabinofuran osidase (E(): 1.4e-35, 58.4% FT identity in 149 aa overlap)" FT /note="SC7H1.01c, xlnA, xylanase A precursor, partial CDS, FT len >147 aa; almost identical to S. lividans XYNA_STRLI FT P26514 endo-1,4-beta-xylanase a precursor (ec 3.2.1.8) FT (XYLANASE A) (477 aa), fasta scores; opt: 926 z-score: FT 1591.1 E(): 0, 97.9% identity in 146 aa overlap. Contains FT N-terminal signal sequence and Pfam match to entry FT glycosyl_hydro3 PF00331, Glycosyl hydrolases family 10, FT score 107.60" FT /db_xref="GOA:Q8CJQ1" FT /db_xref="HSSP:1E0X" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:Q8CJQ1" FT /protein_id="CAD55241.1" FT /translation="MGSYALPRSGVRRSIRVLLLALVVGVLGTATALIAPPGAHAAEST FT LGAAAAQSGRYFGTAIASGRLSDSTYTSIAGREFNMVTAENEMKIDATEPQRGQFNFSS FT ADRVYNWAVQNGKQVRGHTLAWHSQQPGWMQSLSGSALRQAMIDHINGVMAHYKGKIVQ FT WDVVNEAFADGSSGARRDSNLQRSGNDWIEVAFRTARAADPSAKLCYNDYNVENWTWAK FT TQAMYNMVRDFKQRGVPIDCVGFQSHFNSGSPYNSNFRTTLQNFAALGVDVAITELDIQ FT GAPASTYANVTNDCLAVSRCLGITVWGVRDSDSWRSEQTPLLFNNDGSKKAAYTAVLDA FT LNGGDSSEPPADGGQIKGVGSGRCLDVPDASTSDGTQLQLWDCHSGTNQQWAATDAGEL FT RVYGDKCLDAAGTGNGSKVQIYSCWGGDNQKWRLNSDGSVVGVQSGLCLDAVGNGTANG FT TLIQLYTCSNGSNQRWTRT" FT misc_feature complement(211106..211138) FT /note="PS00591 Glycosyl hydrolases family 10 active site" FT misc_feature complement(211346..211663) FT /note="Pfam match to entry glycosyl_hydro3 PF00331, Glycosy FT l hydrolases family 10, score 183.41" FT misc_feature 211505..211663 FT /note="overlap with Cosmid St7H1 from: 1 to: 159" FT misc_feature complement(211505..211693) FT /note="Pfam match to entry glycosyl_hydro3 PF00331, FT Glycosyl hydrolases family 10, from 1 to 71, score 107.60" FT misc_feature 211505..212662 FT /note="overlap with cosmid St10A5" FT misc_feature complement(211505..214089) FT /note="96% match to EM_BA:SLXLNA M64551 Streptomyces FT lividans arabinofuranosidase precursor (abfB) and xylanase FT A precursor (xlnA) genes from: 166 to: 2759" FT RBS complement(211953..211957) FT /note="possible RBS upstream of xlnA" FT RBS 212327..212330 FT /note="possible RBS upstream of abfB" FT CDS 212336..213763 FT /transl_table=11 FT /gene="SCO5932" FT /gene_synonym="abfB" FT /product="arabinofuranosidase" FT /note="SC7H1.02, abfB, arabinofuranosidase precursor, len: FT 475 aa; almost identical to S. lividans TR:P96463 FT (EMBL:M64551) arabinofuranosidase precursor (EC FT 3.2.1.55)(alpha-l-arabinofuranosidase) (arabinosidase) (478 FT aa), fasta scores; opt: 3129 z-score: 1807.5 E(): 0, 95.8% FT identity in 477 aa overlap. Contains N-terminal signal FT sequence" FT /db_xref="GOA:O54161" FT /db_xref="HSSP:1KNL" FT /db_xref="InterPro:IPR000772" FT /db_xref="UniProtKB/Swiss-Prot:O54161" FT /protein_id="CAA16189.1" FT /translation="MHRGSLSRGHTSAVLAAVVAALAALAALLVATTPAQAAGSGALRG FT AGSNRCLDVLGGSQDDGALLQLYDCWGGTNQQWTSTDTGRLTVYGDKCLDVPGHATAPG FT TRVQIWSCSGGANQQWRVNSDGTVVGVESGLCLEAAGAGTANGTAVQLWTCNGGGNQKW FT TGLTGTPPTDGTCALPSTYRWSSTGVLAQPKSGWVALKDFTTVTHNGRHLVYGSTSSGS FT SYGSMVFSPFTNWSDMASAGQNAMNQAAVAPTLFYFAPKNIWVLAYQWGSWPFIYRTSS FT DPTDPNGWSAPQPLFTGSISGSDTGPIDQTLIADGQNMYLFFAGDNGKIYRASMPIGNF FT PGNFGSSYTTIMSDTKANLFEGVQVYKVQGQNQYLMIVEAMGANGRYFRSFTASSLSGS FT WTPQAASEGNPFAGKANSGATWTNDISHGDLVRDNPDQTMTVDPCNLQFLYQGKSPNAG FT GDYNSLPWRPGVLTLRR" FT CDS complement(213747..214922) FT /transl_table=11 FT /gene="SCO5933" FT /gene_synonym="SC7H1.03c" FT /product="putative membrane protein" FT /note="SC7H1.03c, possible membrane protein, len: 391 aa; FT C-terminal part similar to TR:Q9L0E7 (EMBL:AL161803) FT Streptomyces coelicolor hypothetical protein SCD31.20, 181 FT aa; fasta scores: opt: 592 Z-score: 665.9 E(): 1.8e-29; FT 53.514% identity in 185 aa overlap. Contains possible FT hydrophobic membrane spanning regions. Contains PS00213 FT Lipocalin signature, though this may be spurious" FT /db_xref="GOA:O54162" FT /db_xref="InterPro:IPR010822" FT /db_xref="UniProtKB/TrEMBL:O54162" FT /protein_id="CAA16190.1" FT /translation="MSRPSRAAPAPAEDGADQGDGISIRTPPTRVVALVTVAATVVTVV FT LGAVTGTAVLLIGLLVFLPAFASALCTPRQTTLVSAWVSIVVIVPVALSTEQLADRVTL FT ALFALGFGALAVYGSWLRITREGTLVRLRSTAAAMQRQILRPLPLLTDDVLVDGVYEPV FT QQDKLVGGDIYDVAATPWGTRVLIGDVQGKGLPAIGMAIDVVGAFREAAHREPTVTALV FT DSLEAAVVRHNGYAEQRGEPERFVTAVVLGVDTGAETQLVTCGHIPPYLLHDGTVTAVG FT AGTEHAPLGLADLVDEPRTVSWFPFPAGATLLLCTDGLTEARSPAGAFYPLETRLAGHV FT DITAGRLTHALVDDVHAFTEGPQQDDLAVLTVRRSPHRMRSPSVGEVSAAG" FT misc_feature complement(214554..214595) FT /note="PS00213 Lipocalin signature" FT RBS complement(214930..214935) FT /note="possible RBS upstream of SC7H1.03c" FT CDS 215150..215752 FT /transl_table=11 FT /gene="SCO5934" FT /gene_synonym="SC7H1.04" FT /product="putative sigma factor" FT /note="SC7H1.04, possible sigma factor, len: 200 aa; some FT similarity to sigma factors (ECF subfamily) from diverse FT organisms e.g. Alcaligenes eutrophus CNRH_ALCEU P37978 rna FT polymerase sigma factor cnrh (191 aa), fasta scores; opt: FT 230 z-score: 337.3 E(): 1.4e-11, 29.5% identity in 183 aa FT overlap" FT /db_xref="GOA:O54163" FT /db_xref="InterPro:IPR013249" FT /db_xref="UniProtKB/TrEMBL:O54163" FT /protein_id="CAA16191.1" FT /translation="MSDRELWARAADGDREAFGRIFDRHGKAVYNHLFRRTADWSEAED FT LTSTVFLHAWRRRADTVLDRDSALPWLLGIANGQLSNTRRRLRRAEALLHRLVSHEESV FT GDHADRVAGRIDDERRMSEIHRALARLPRHEREVVELCVWSGLDQQAAAAVLKVAVGTV FT KSRLHRARRRLGADLGGAAAPPPFSSRNPVNEKEVAR" FT RBS 215735..215742 FT /note="possible RBS upstream of SC7H1.05" FT CDS 215749..216642 FT /transl_table=11 FT /gene="SCO5935" FT /gene_synonym="SC7H1.05" FT /product="putative membrane protein" FT /note="SC7H1.05, putative membrane protein, len: 297 aa. FT Contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:O54164" FT /protein_id="CAA16192.1" FT /translation="MNDPQGVPAAPSDRDLPNHRRTREELLMKIGPENNGTPSRRRWAI FT RWGVPLGVATGVTAMSVAAVVVLGGSGSAGPGAADPAHGGADPANSTPAPSPSASSSPG FT GTSPEADFTVTDATTTPIDAGTATRILSSCLGADASRYHAVVAVRTPLATEDWDGVVVA FT VDSAGQYVQCQSKGDKGTSQDSPPTFINDRLWGTGRIVEYFDSMLMPAGEGKYLSLGAG FT HYSSDVAKITVSYGEDPKQYPARMADGAFVYGAALSPDTPPGPRYTGPSPYVHAYDASG FT REIYNQAEDPKFTDEQ" FT CDS complement(216626..216787) FT /transl_table=11 FT /gene="SCO5936" FT /gene_synonym="SC7H1.06" FT /product="hypothetical protein SC7H1.06" FT /note="SC7H1.06, unknown, len: 53 aa" FT /db_xref="UniProtKB/TrEMBL:O54165" FT /protein_id="CAA16193.1" FT /translation="MMLEGSAPEPAWAAVRRARRARVPDTEEQHAWTLEFFRRISPRGQ FT DGSPTARR" FT CDS complement(216802..217170) FT /transl_table=11 FT /gene="SCO5937" FT /gene_synonym="SC7H1.07c" FT /product="hypothetical protein SC7H1.07c" FT /note="SC7H1.07c, unknown, len: 122 aa" FT /db_xref="UniProtKB/TrEMBL:O54166" FT /protein_id="CAA16194.1" FT /translation="MTPEPSGPVLHTVDRPHRPGRLRTMARPRGGAHLAGDMAALRDAG FT VDVVVCALPEAERADLGLTDEPRLAEAAGLRFVALPVPDFTVPSVPAVLPPLRELTEGC FT GREPMSSRTAAAASAGPP" FT CDS complement(217167..217775) FT /transl_table=11 FT /gene="SCO5938" FT /gene_synonym="SC7H1.08c" FT /product="conserved hypothetical protein SC7H1.08c" FT /note="SC7H1.08c, unknown, len: 202 aa; some similarity in FT C-terminus to Mycobacterium tuberculosis hypothetical FT protein TR:P71839 (EMBL:Z80226) MTCY369.30C (129 aa), FT fasta scores; opt: 240 z-score: 383.0 E(): 3.8e-14, 41.2% FT identity in 102 aa overlap" FT /db_xref="GOA:O54167" FT /db_xref="InterPro:IPR001279" FT /db_xref="UniProtKB/TrEMBL:O54167" FT /protein_id="CAA16195.1" FT /translation="MLTWVRITKYVHSCVRLEHEGGTLVIDPGVWSESEALAGADAVLV FT THEHNDHVDLLRLRGLDVPVYAPKSARLPGLDFNGVVAGEEFTAAGFRVPPRGGRHARI FT YGDRPDCANLGYLVDDRLYHPGDSLHLPDRPVETLLVPLQGSWMKTDEAIDFVRAADPE FT RAFGIHDGQVNERGLSSLNGWLTDECGGRYRWLAPGVSA" FT RBS complement(217178..217181) FT /note="possible RBS upstream of SC7H1.07c" FT CDS 217808..218281 FT /transl_table=11 FT /gene="SCO5939" FT /gene_synonym="SC7H1.09" FT /product="peptidylprolyl isomerase" FT /note="SC7H1.09, probable peptidylprolyl isomerase, len: FT 157 aa; similar to many eg. Streptomyces chrysomallus FT TR:P77949 (EMBL:U64692) cyclophilin sccypb (EC 5.2.1.8) FT (peptidylprolyl isomerase) (175 aa), fasta scores; opt: 402 FT z-score: 552.5 E(): 1.4e-23, 49.6% identity in 123 aa FT overlap. Contains Pfam match to entry pro_isomerase FT PF00160, Peptidyl-prolyl cis-trans isomerases, score 77.82" FT /db_xref="GOA:O54168" FT /db_xref="HSSP:1H0P" FT /db_xref="InterPro:IPR002130" FT /db_xref="UniProtKB/TrEMBL:O54168" FT /protein_id="CAA16196.1" FT /translation="MAENVLRGGPEGPDPLTGTTGRGGFCDGTVFHRRVPGFVVRGGDR FT LGTGHGSAGYRIPDEIRPDQGFEQPFPLAMANLGRDSTGPQFFITLAPAPRLNGQYTIF FT GQVADERSQDVVRAIAAAPTAVRLDRVTIAADQRSRRRRALWPGGGTAMVTLI" FT misc_feature 217877..218179 FT /note="Pfam match to entry pro_isomerase PF00160, FT Peptidyl-prolyl cis-trans isomerases, from 43 to 158, score FT 77.82" FT RBS 218318..218321 FT /note="possible RBS upstream of SC7H1.10" FT CDS 218329..218988 FT /transl_table=11 FT /gene="SCO5940" FT /gene_synonym="SC7H1.10" FT /product="transferase" FT /note="SC7H1.10, probable transferase, len: 219 aa; similar FT to eg. MENG_ECOLI P32165 FT s-adenosylmethionine:2-demethylmenaquinone FT methyltransferase (161 aa), fasta scores; opt: 211 z-score: FT 265.9 E(): 1.3e-07, 34.1% identity in 126 aa overlap" FT /db_xref="GOA:O54169" FT /db_xref="HSSP:1NXJ" FT /db_xref="InterPro:IPR005493" FT /db_xref="UniProtKB/TrEMBL:O54169" FT /protein_id="CAA16197.1" FT /translation="MFIAAATDGVSVAPSWDRAAAADTRRLGEVPAAHVGDALERMTVM FT DGGIRLLTERAALLGNALTVDVRSGDNLAVHRALDEARPGDVLVVNGHGDTTRALVGDL FT IGEIMVNTGVTGAVVDGAVRDVRALSEMGLTVYARAITPAGPFKDGPGAVGRPVAVGGM FT VVEAGDVLVGDADGVVVVPRRRVREAVEAVGGVAEKEDALRGRILAARPDRAVVAR" FT RBS 218973..218977 FT /note="possible RBS upstream of SC7H1.11" FT CDS 218985..220133 FT /transl_table=11 FT /gene="SCO5941" FT /gene_synonym="SC7H1.11" FT /product="aminotransferase" FT /note="SC7H1.11, probable aminotransferase, len: 382; FT similar to many eg. AAT_BACST Q59228 aspartate FT aminotransferase (ec 2.6.1.1 (393 aa), fasta scores; opt: FT 683 z-score: 686.1 E(): 5.1e-31, 35.0% identity in 374 aa FT overlap. Contains Pfam match to entry aminotran_1 PF00155, FT Aminotransferases class-I, score 177.68" FT /db_xref="GOA:O54170" FT /db_xref="HSSP:5BJ4" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:O54170" FT /protein_id="CAA16198.1" FT /translation="MIATPPASRIAELRRRSRRPALAPAPPGAVSLAMGEPDFPTPPTV FT VQAAVSALREGHTHYADQRGLRELRAALAARLPERPGGAWDADDVLVTHGATAALAAVV FT LATVGPGDRVVVPEPAYSLYADLVVLAGGTVDFVPLAPDLHWDLDALAAALPGAAMMIF FT SNPSNPTGIVHRREELEALGKLLDGTDVLVVSDEAYHRLAYPGHEPVSALEIESLRGRT FT VYVQTFSKTYAMTGWRVGYLTGPREVLDAAAQVHRTWNGSLNTAVQHAALAALDLPDGV FT VGAMADRYRQRRDLVVGRLSGVPGLHLVPPEGAFYGFLRYDADRPSEMVARELAACQVL FT VRAGAEYGPSGEGHLRISFAASEDDLWVGLERIVRYFAEARS" FT misc_feature 218988..220121 FT /note="Pfam match to entry aminotran_1 PF00155, FT Aminotransferases class-I, from 1 to 433, score 177.68" FT RBS 220205..220209 FT /note="possible RBS upstream of SC7H1.12" FT CDS 220216..220833 FT /transl_table=11 FT /gene="SCO5942" FT /gene_synonym="SC7H1.12" FT /product="hypothetical protein SC7H1.12" FT /note="SC7H1.12, unknown, len: 205 aa; very weak similarity FT to downstream ORF SC7H1.21 (203 aa), (E(): 0.085, 26.9% FT identity in 208 aa overlap). Contains possible FT Helix-turn-helix motif at aa 41-62, Score 1089 (+2.90 SD)" FT /db_xref="GOA:O54171" FT /db_xref="InterPro:IPR001647" FT /db_xref="UniProtKB/TrEMBL:O54171" FT /protein_id="CAA16199.1" FT /translation="MTDQQAAPRGRRKPRSDTRRNHRRLLQAVGELAREAPDRLTMQAV FT ASRAEIGPATAYRYYSSVDDVLAAYVLSVVEQLRDFSLASSAQGRPLFDALVDKWVDLL FT AEHGPALVQLRSRRGYLERLHDGNEIIVALRDAWSEPVRGLLDDVGLPDGMLEHALFLS FT NMIFDPREIQDLLRETGLSRREVIARLTEAYCGALRGWVRAG" FT RBS 221014..221019 FT /note="possible RBS upstream of SC7H1.13" FT CDS 221025..221810 FT /transl_table=11 FT /gene="SCO5943" FT /gene_synonym="SC7H1.13" FT /product="putative hydrolase" FT /note="SC7H1.13, probable hydrolase, len: 261; weak FT similarity to several diverse hydrolases eg. TODF_PSEPU FT P23133 2-hydroxy-6-oxo-2,4-heptadienoate hydrolase (276 FT aa), fasta scores; opt: 196 z-score: 344.3 E(): 5.5e-12, FT 30.7% identity in 270 aa overlap" FT /db_xref="GOA:O54172" FT /db_xref="InterPro:IPR000073" FT /db_xref="UniProtKB/TrEMBL:O54172" FT /protein_id="CAA16200.1" FT /translation="MTKHRQETVRAGELDVGFLDSGDGVPLLLVHGGESDRTQFATLRA FT GLGAGIRAISYDQRDSGITVNPPVPYTPEVLADDLVDLLDALGLARAHLLGTSFGGAVA FT QHAARRHPERVASLVLVATTPSYAMGSAAIDELLEMSHEDRQQAAADYFFTPEGQAGQR FT ARPAGTLTRRTPEQSVRRHDAARRHEIRDGLGGITAPTLIVHGTQDRLAPYEGALLMER FT RIPNAELCPIEGGRHGIAVEFADTVAHRVREFLGVEGHG" FT RBS 221796..221799 FT /note="possible RBS upstream of SC7H1.14" FT CDS 221803..222951 FT /transl_table=11 FT /gene="SCO5944" FT /gene_synonym="SC7H1.14" FT /product="hypothetical protein SC7H1.14" FT /note="SC7H1.14, unknown, len: 382 aa" FT /db_xref="UniProtKB/TrEMBL:O54173" FT /protein_id="CAA16201.1" FT /translation="MADAARDVADRMAEAARAWLDSLDAGRRGAAAGPAPDPGTPGEAE FT GERTRWYYTPTDHGGLTLHQQRPAQQRLAMRLVASGLSDAGYVTVATVLGLENVLDHVE FT GFSVNWGRERTRDPGMYYLRVFGEPGGPRPWGWRFGGHHVSLNNLVVDGRVVATTPCFL FT GADPAASPLLGGSALRPLGTAEDLARELVRSLRPEAAARATLLPRAPNDIVAGNSARVG FT DRVIRRGELWRPGTHIPDRAEQPSTGLDGDERRALALTPAPKGVSGAELDSLQRELLRA FT LLGAYLGRVPDGVSPLPRYDDPAALDAVHLAWAGPTAPGEPHYYRLQGPRLLIEWTNVH FT RGANHAHAVWRDPETDFGGDVLAAHHAAHHAARHAAHHPNGM" FT CDS 222948..224768 FT /transl_table=11 FT /gene="SCO5945" FT /gene_synonym="SC7H1.15" FT /product="putative transferase" FT /note="SC7H1.15, probable transferase, len: 606 aa; similar FT to TR:Q54353 (EMBL:X64651) S.lincolnensis lmbA gene for FT lincomycin condensing protein (601 aa), fasta scores; opt: FT 921 z-score: 1470.0 E(): 0, 45.8% identity in 600 aa FT overlap and to other gamma-glutamyl transferases" FT /db_xref="GOA:O54174" FT /db_xref="InterPro:IPR000101" FT /db_xref="UniProtKB/TrEMBL:O54174" FT /protein_id="CAA16202.1" FT /translation="MTDMAGRPPSPPDAPAHTTRPTLRGSFGMCASTHWLATATAQSVL FT ERGGNAFDAAVAGAFVLHVAEPHLNGPGGDLVAVLATAADPSPRVLAGQGPAPRGATIE FT HFRAEGLDHVPGAGALAAAVPGAVDSWLWLLAEFGTWELADVLAYAIAYAERGVPVVPQ FT LARVLATVEELFRTHWPTSYALWMPEGRVPAPYATLVNPAYARTLRRLGTAPSGGTRTA FT RIEAARRAWRTGFVAQAVAEFAAVPHRHSSGGDHAGVITAADFTDFHPSLEPAVTARFR FT GTTVAKAGPWSQGPVLLQALTILDHFDDARLDPSTAEGVHTLTEALKLALADREAYYGH FT LDPAAADALLRRLLSPRYGKERARLIRPLASTAFRPGHIGVTPYTPPLVTRGSAQQADG FT VGEPTVQQTGETRGDTCHLDVVDRWGNIVSATPSGGWLQSSPAVPELGFALGTRLQMTW FT LDPAAPSRLAPGRRPRTTLTPTLLLRDGNPVAALGTPGGDQQDQWQLIYLVRTLALGMD FT PQEAIDAPAFHTTAVPSSFWPRTWTPGGLVIEERAGGAVVEELRARGHAVTVSGPWSQG FT RLSVVTRDPDSGVLRAAANPRGAQGYAAGR" FT CDS 224765..225538 FT /transl_table=11 FT /gene="SCO5946" FT /gene_synonym="SC7H1.16" FT /product="putative membrane protein" FT /note="SC7H1.16, putative membrane protein, Gly-, Ala-rich FT protein, len: 257 aa. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="InterPro:IPR010699" FT /db_xref="UniProtKB/TrEMBL:O54175" FT /protein_id="CAA16203.1" FT /translation="MNVRRRVTQPGLMLALTFATGVVDAVGYLRLDQVFAGNMTGNVVI FT LGMAATGGGTGLPVLGPVVALASFLAGAATAGRVLRTAAPGWSSRCGALLGGVGLVLTA FT TALGPALVGADTSGARAGMASSLALAMGAQAATARHLAVRDVTTVVVTSTLTGLAADSR FT LGAARGRGALRRTAAVALIVAGAAAGALLCQVHEGLAVAAAACVVLAVTALGSRAAPAT FT TGAPSTAPPTAPATASSTAPSTASSTAPSTVLPRP" FT RBS 225543..225547 FT /note="possible RBS upstream of SC7H1.17" FT CDS 225553..226950 FT /transl_table=11 FT /gene="SCO5947" FT /gene_synonym="SC7H1.17" FT /product="integral membrane protein" FT /note="SC7H1.17, probable integral membrane protein, len: FT 465 aa; weakly similar to many eg. Mycobacterium FT tuberculosis TR:O07753 (EMBL:Z97193) MTCY180.41C (687 aa), FT fasta scores; opt: 440 z-score: 332.4 E(): 2.5e-11, 26.6% FT identity in 413 aa overlap. Contains possible hydrophobc FT membrane spanning regions" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:O54176" FT /protein_id="CAA16204.1" FT /translation="MTTTLAPPVPIGKAAVGALGILALSTGALESVVSPTIPLLERELD FT MSQSEGALLSIVLLITGALITPLAGKFGDRYGGKKVLIRLMAVVSLGGTVSALAPNLPV FT LLVGQVLQGAMIGALPLSFIVVRKHLPAGESKVAIGVVSGLFVGGSMVGMLSAGPVAEQ FT LSRHWMFALPTIAVVGSTLLVNRLMPADPPGRPDDVGIDWPGLLLLSGMLTTLMLVLAL FT APEAGSAPLVLVALVVLLAVFVTGWVRVERRAAAPMIDLNMLARPAIWKACALTFVICL FT GTTMAVYLVPQLLDERGDGYGFRASATEIGLYLLPGAVAATLAGPLGGLGDRRFGSRAV FT VNTGVVMMAVGLLAVAAVHTEIWHLVVGKVLIALANGLCVTAMMTSTATAVDPNDTGIA FT TSLILVSRVLGSAVGGQLGGALLTAGTPSGSEVAAESAYVTGFVIAGIVVLSALFVTRT FT MSKGVKA" FT RBS 226934..226939 FT /note="possible RBS upstream of SC7H11.18" FT CDS 226947..228140 FT /transl_table=11 FT /gene="SCO5948" FT /gene_synonym="SC7H1.18" FT /product="putative oxidoreductase" FT /note="SC7H1.18, possible oxidoreductase, len: 397 aa; weak FT similarity to TCMG_STRGA P39888 tetracenomycin polyketide FT synthesis hydroxylase (572 aa), fasta scores; opt: 72 FT z-score: 275.1 E(): 4e-08, 26.0% identity in 369 aa FT overlap. Also similar to M. tuberculosis hypothetical FT protein Y08M_MYCTU Q11058 MTCY50.22c (372 aa), fasta FT scores; opt: 949 z-score: 613.3 E(): 5.8e-27, 45.9% FT identity in 355 aa overlap" FT /db_xref="GOA:O54177" FT /db_xref="InterPro:IPR003042" FT /db_xref="UniProtKB/TrEMBL:O54177" FT /protein_id="CAA16205.1" FT /translation="MTRTAPRRSVLISGASIAGPALAFWLNRHGYEVTVVEKAGTLRSG FT GYPIDVRGTALDVVERMGILPQLRDAHIDLRRITFLDADGDEVTSLHPHAVTGGVTGRD FT LEIRRGDLTDALYMAVRDDVEFLFNDSIDTLDQSGPGVDVTFHGGGSRRFDMVFGADGM FT HSRTRETLFGPEERFHRHLGYCFAVFTMPNTLGLSHETVMWNTPGRAAAVYAVGDDEEV FT HAFLNFAQPEPPYDAFGDPEAQRALLADVFADAGWEVPGILGALHDADDVFFDAVGQIR FT MPRWTEGRVALLGDAAYAPSFLTGQGTSLALVGAYMLAGSLAGRNHAEGFAAYEHATRD FT FVTLNQDLVGEGGATLFPTTVQALEQRNARLRALSAMPAPEPRPAHSALTLPSFGVR" FT CDS 228425..228973 FT /transl_table=11 FT /gene="SCO5949" FT /gene_synonym="SC7H1.19" FT /product="hypothetical protein" FT /note="SC7H1.19, unknown, len: 182 aa" FT /db_xref="InterPro:IPR009412" FT /db_xref="UniProtKB/TrEMBL:O54178" FT /protein_id="CAA16206.1" FT /translation="MLNHWVVVPTCLPLVLRRCHTCASRHFRASGRFRVNANHKLLDAW FT LLVLCTACGDTAKLTVLERMNVRSVRPGLLDRLHANDPGLAAELLQDPIVQRRNRIALD FT WADAWRLDTGGPDHPDREVIDVSVRFAARIPVRPVRLIAEGCGLARAEAERLIAEGRLV FT SAVRLSDRLCGDFTFTLKR" FT CDS complement(229093..230544) FT /transl_table=11 FT /gene="SCO5950" FT /gene_synonym="SC7H1.20c" FT /product="export protein" FT /note="SC7H1.20c. probable export protein, len: 483; FT similar to many members of the drug resistance translocase FT family eg. Streptomyces lipmanii PUR8_STRLP P42670 FT puromycin resistance protein pur8 (503 aa), fasta scores; FT opt: 907 z-score: 636.6 E(): 2.9e-28, 38.6% identity in 477 FT aa overlap. Also weakly similar to upstream protein FT SC7H1.27 (533 aa) (E(): 7.9e-15, 28.6% identity in 461 aa FT overlap)" FT /db_xref="GOA:O54179" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:O54179" FT /protein_id="CAA16207.1" FT /translation="MSTTATATAGVTARAGADPQRLTGRSKLVLAVLLVAQFMLAVDFS FT ILNVALPAIGDGLGFALSDLQWIATSFALSAAGFTLFLGRVGDLVGRKRIFMGGIGLLG FT LASLLGGLTTSPEVLLAARVAQGLATAAATPAGLSLLTTSFAEGPLRQKALGINGALMS FT AGFTTGAILGGVLTDLLSWRWTFFVNVPVALAVVLVAPAVIKESRPAARAGLDLPGALT FT VTLGLLGLVYGMTQAGAYGWTHPHALAGLAGGALLLAAFVLIERTVAAPLVPLGTLRRR FT NVAWGNVLGLLAFATETSLVYLLTLYLQKTLGFSALAAGVSFGVLGAGTVVGGLVAPRL FT LARTSTPAVLVGGGIVQAVSTAALLFLGTTTGASLALLLPATFLGGVGNMLVIVGFMVT FT ATSGLPDAEQGLATGLASMSQQVGITMGTPVMSAVVTAGTAGAATASAVHRGVTTAIAV FT NAALVLLGVAAAALLLRGRTARPSG" FT RBS complement(230552..230555) FT /note="possible RBS upstream of SC7H1.20c" FT RBS 230683..230686 FT /note="possible RBS upstream of SC7H1.21" FT CDS 230692..231303 FT /transl_table=11 FT /gene="SCO5951" FT /gene_synonym="SC7H1.21" FT /product="putative transcriptional regulator" FT /note="SC7H1.21, probable transcriptional regulator, len: FT 203 aa; similar to many eg. Streptomyces hygroscopicus FT TR:Q54288 (EMBL:X86780) regulator of antibiotic transport FT complexes (204 aa), fasta scores; opt: 263 z-score: 351.4 FT E(): 2.2e-12, 33.7% identity in 196 aa overlap. Contains FT probable Helix-turn-helix motif at aa 41-61, Score 1399 FT (+3.95 SD) and Pfam match to entry tetR PF00440, Bacterial FT regulatory proteins, tetR family, score 23.60" FT /db_xref="GOA:O54180" FT /db_xref="InterPro:IPR012287" FT /db_xref="PDB:2ID3" FT /db_xref="UniProtKB/TrEMBL:O54180" FT /protein_id="CAA16208.1" FT /translation="MPDPAAPGTLRPGGRTARIREAVLLAAGDALAADGFDALDLGEIA FT RRAGVGKTTVYRRWGTPGGLAADLLADMAEQSLPRADTGALEEDLRANARLVVRTLDDP FT RQGRLFRALIAASLCNEQAAEALHRFYAVRVDEWAGCVRDAVARGEVPDGTDPHGVVAA FT VSAPLYYALLNTGRSLTEADADRAARAASTAARAGVWVTG" FT misc_feature 230758..230898 FT /note="Pfam match to entry tetR PF00440, Bacterial FT regulatory proteins, tetR family, from 1 to 48, score FT 23.60" FT RBS 231537..231540 FT /note="possible RBS upstream of SC7H1.22" FT CDS 231547..232299 FT /transl_table=11 FT /gene="SCO5952" FT /gene_synonym="SC7H1.22" FT /product="putative membrane protein" FT /note="SC7H1.22, putative membrane protein, len: 250 aa. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:O54181" FT /protein_id="CAA16209.1" FT /translation="MLPGVRPRWEVRVVRRAVLRLLLASVTGGIAGLVLYSLTRVTSRS FT LFAVTGALAAVVALLASEWYRKAARLTEVKVTIPQLSELTFAVNNDSRQVAWHMFVETV FT TRVSTQPLADDEGVVREALTSMYGLFATTRETLKVTRPSPVVPSGQTVEYLAITMLNRE FT LRPFLSKWHPRLREFEMAHPDDSESTWPDNAACRAELQRVQQHIHGYAAGFARLAGVRE FT ADALIGQVPGPRDEADDLRRDAGRTARP" FT CDS 232302..235043 FT /transl_table=11 FT /gene="SCO5953" FT /gene_synonym="SC7H1.23" FT /product="putative membrane protein" FT /note="SC7H1.23, putative membrane protein, len: 913 aa; FT weakly similar to many members of the eukaryotic FT beta-transducin family e.g. YA3A_SCHPO Q09715 hypothetical FT Trp-Asp repeats containing protein (614 aa), fasta scores; FT opt: 139 z-score: 352.6 E(): 1.9e-12, 28.8% identity in 250 FT aa overlap. Contains possible membrane spanning domain FT around aa 200 and 3x Pfam match to entry G-beta PF00400, WD FT domain, G-beta repeats, scores; 27.34, 28.55 and 25.74" FT /db_xref="GOA:O54182" FT /db_xref="HSSP:1ERJ" FT /db_xref="InterPro:IPR019781" FT /db_xref="UniProtKB/TrEMBL:O54182" FT /protein_id="CAA16210.1" FT /translation="MGGGDGRRIDAFVSYSRAADSRLAPSIQRGLARLAKKWYRTRALN FT VFRDQTDLSASHALGASIERALADARFFVLLASPAAAESKWVAKEIEFWQRNRTSDTFL FT VALTDGTIRWDDEAGDFDWSVTDALPRSLSGYFEAEPLWQDLTWSRDADRLSLWHAGFR FT DAVATLAAPIHGSSKRALDNAEVKEHRALLLVGALATALILTLAVSFGIQYWFATAERD FT RANANARDATVMSAIQRAQVELADAETGYDVSAYRRLMAARSLAGRPSVEGAAYDAALD FT AAYSRPNLLRVTEVDSGPDSRAAMTVDGGRVAFGGKEQPTLWSPGTGRPSGPALEAAET FT TDSKALALAFSRDGKRLAAAYEAAVVLWDVASGKKINEFATDRRTTTSLALSPDGTTVA FT VAGGGLRIWDAGSGRRIGEPLGVTGDRVVFSPDGRKLAFDALNDGGSEVHVRGVGAEGA FT GEVVIPYPHDVISGIAFTPDTDALAVGTEDGGLRLWDPDSGAAEGRAMSGHQGAIRAIA FT FAAGGSRIATAGADRTIRQWNAETGSPIGFPLTGHAGPVDFIAFSRGGSELVSLGEDAT FT LRRWDAGNALLRTGPDDASAPDALAVAPRGAKVAVGGREGVRVFNQETGVQVAALDLPQ FT GVLSLSYSPDGTSLLIVSPDALRLWEEGAEARTVTLDSSVGPVAGAAFMPHGRQIVVGS FT YAGKLLFEDLDDEATGTPGASIDITCAARHLAVSQDGMQVAYACDDTGGVADAEAGGVR FT TFEAEDRVSALVISPDGRTLILGTLDGTLWRLEHGAEALVGVGVHRGAVRSVAYGPDGR FT WFASAGEDGSVVVHPHGAREISARIPAHTGPVEAVAFSGDGSRLISLGADKAARVWHVF FT RDPPGDLCERITYNMSESDWKKWISDSFGYRDQCAGKPRAHG" FT misc_feature 233817..233915 FT /note="Pfam match to entry G-beta PF00400, WD domain, FT G-beta repeats, from 1 to 34, score 27.34" FT misc_feature 233946..234044 FT /note="Pfam match to entry G-beta PF00400, WD domain, FT G-beta repeats, from 1 to 34, score 28.55" FT misc_feature 234810..234908 FT /note="Pfam match to entry G-beta PF00400, WD domain, FT G-beta repeats, from 1 to 34, score 25.74" FT RBS 235134..235137 FT /note="possible RBS upstream of SC7H1.24" FT CDS 235142..237439 FT /transl_table=11 FT /gene="SCO5954" FT /gene_synonym="SC7H1.24" FT /product="chitinase (putative secreted protein)" FT /note="SC7H1.24, probable chitinase (putative secreted FT protein), len: 765 aa; similar to many eg. S. lividans FT CHIT_STRLI P36909 chitinase c precursor (ec 3.2.1.14) (619 FT aa), fasta scores; opt: 292 z-score: 779.5 E(): 0, 35.1% FT identity in 752 aa overlap. Contains PS01095 Chitinases FT family 18 active site signature, and possible N-terminal FT region signal peptide sequence" FT /db_xref="GOA:O54183" FT /db_xref="HSSP:1K85" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:O54183" FT /protein_id="CAA16211.1" FT /translation="MFHRRRPPNRTGVRIAALLTALLLPLAALTALAAPARAAGTLTAT FT FTSQSNGSGWTGKYVVRNDGTAASDGWTLEFDLPPGVSVSGHLYGEATVSGRHVTVENA FT YYNGRVPAGGTTEPYSYQFSATGPVGTPTGCTVNGDKCDGTPDVPPAAPGAPEATAVTA FT HTVALTWAAARPGDHPVTSYEVLEGTETVATTSGTSATVTGLTPATSYTFTVRATDKRG FT NVGPASEPLTVETVDPATDPTPPTAPGNPRATGRTATTVGLAWDRSTDNVAVAAYDVYR FT GDTLAKTVGADTTTATVDGLSPATAYTFTVRARDTADNSSAPSAAVRATTDDVAGEGKQ FT LKVGYFVQWGIYGRQYFVKNLDTSGAAKQLDVVNYAFENLDPTSLTCQAGVTKGTSGNP FT QDPDEGTGAGDADADYARPMSAAQSVDGVADDGWGKLRGNLNQLKKLKAKYPHLKVVVS FT LGGWTYSKFFSDAAATPESRKKFVESCIDVWIKGNLPVYNGAGGPGTAAGIFDGIDIDW FT EWPGSEGHPGNHYGAQDKDNLTALLAEFRTRLDALGGEHRLLTAFTPADPAKIEAGWDL FT TRIFDSLDYANVQGYDFHGSGSDNSWEPDRTGHASNLHTDAEDPYPFHFSVENAIQTYL FT DAGVNPRKLTVGFPFYGRGWQGVGEGGAAGEWQDAGGAAPGQFPAEAGVRGYSNLIGSY FT PSMTVHHDEESVSTFGYTGPGGQWWSFDDTWSIGKKTDWVKSKGLLGGFVWEMSGDTAD FT GRLMTALDDGLE" FT misc_feature 235861..236068 FT /note="weak match to repeats from EM_BA:SL22894 U22894 FT Streptomyces lividans amplifiable element AUD1 (3863-4034, FT 4141-4348, 9515-9686, 9793-10000)" FT misc_feature 236669..236695 FT /note="PS01095 Chitinases family 18 active site signature" FT CDS complement(237506..237940) FT /transl_table=11 FT /gene="SCO5955" FT /gene_synonym="SC7H1.25c" FT /product="putative membrane protein" FT /note="SC7H1.25c, putative membrane protein, len: 144 aa; FT similar to Mycobacterium tuberculosis hypothetical protein FT O06193 (EMBL:Z95387) MTCY1A10.13 (141 aa), fasta scores; FT opt: 459 z-score: 576.2 E(): 6.7e-25, 56.4% identity in 140 FT aa overlap. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:O54184" FT /protein_id="CAA16212.1" FT /translation="MDTTSAAVAGAVTFLWLGMVLAISFLEAPLKFRAPGVTIPIGLGI FT GRMVFRALNLAEAVLAAAVVVAVATGGPSAAVVTLTAVAVAVLAVQLAVVRPRLNRRSD FT AVLAGEDPAENRSGAHLHYVALEIVKVLALLALGCTVLAA" FT RBS 237896..237899 FT /note="possible RBS upstream of SC7H1.26" FT CDS 237903..238715 FT /transl_table=11 FT /gene="SCO5956" FT /gene_synonym="SC7H1.26" FT /product="putative regulatory protein" FT /note="SC7H1.26, possible regulatory protein, len: 270 aa; FT contains probable Helix-turn-helix motif at aa 91-112, FT Score 1562 (+4.51 SD) and Pfam match to entry tetR PF00440, FT Bacterial regulatory proteins, tetR family" FT /db_xref="GOA:O54185" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:O54185" FT /protein_id="CAA16213.1" FT /translation="MTAPATAADVVSIAETSSFSSSFSMSCRVRPRARMYDHVHAALPA FT PPASSRPEVPVTKPVAREPQRRNARSNRARILATARRELGRNPDTTLEELARAAGVVRR FT TLFGHFPGRAALLEALAEEASEVLRGAMAEAAGPDEPADRALAHFTLLMWSVGDRYRML FT LALARHDLGVERVAEILAPARAEVTAILERGRRDGVFPAHLPPAVLSAGLEAMVVALLE FT QVNTGALEDDGTRTAVAMLIAAGVPERRARAVVEAVGPAVRAKSVPAE" FT RBS complement(237954..237958) FT /note="possible RBS upstream of SC7H1.25c" FT misc_feature 238167..238262 FT /note="Pfam match to entry tetR PF00440, Bacterial FT regulatory proteins, tetR family, from 17 to 48, score FT 25.03" FT RBS 238861..238864 FT /note="possible RBS upstream of SC7H1.27" FT CDS 238871..240472 FT /transl_table=11 FT /gene="SCO5957" FT /gene_synonym="SC7H1.27" FT /product="putative transport protein" FT /note="SC7H1.27, probable transmembrane transport protein, FT len: 533 aa; similar to many eg. S. pristinaespiralis FT TR:Q54806 (EMBL:X84072) integral membrane protein (501 aa), FT fasta scores; opt: 1088 z-score: 1144.1 E(): 0, 39.5% FT identity in 524 aa overlap. Also weakly similar to upstream FT ORF SC7H1.20c (E(): 4.2e-12, 28.6% identity in 461 aa FT overlap)" FT /db_xref="GOA:O54186" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:O54186" FT /protein_id="CAA16214.1" FT /translation="MPLLATTPVEKMPGPYARRWWALLVLCLSLLIVVMANTSLIVAAP FT DMTTDLGLSSSDLQWVIDGYTVPYAALMLVLGAIGDKYSRRGALVTGLVIFAGGSVMGS FT LVHETGLVIAARAVMGVGAAVVMPATLSLLVAVFPKGERARAITAWTATSGLAIAVGPL FT VAGWLLEDHAWGSTFLVNVPVAVFAVVGALVLVPPSRAAGMGRIDYVGGLLSIVSVGSL FT VYATIEGPHFGWGAGPVTAAVVAAVGLIGFVTWELRHPHPMLDVRRFLLRPFSGSMLAV FT LFFFFGTYGAIYYATQFLQFVLGFGALETGVRLLPLAGAVFVGAAVTGRLTPRLGVRAM FT VGSGMAIGTVGVFLLVLIDQGSTYADFLAPMLLLGLAIGLSVSPATDTIMGSFPESELG FT VGGGANDTALELGGSLGIAVLGSLLGTAYRDELAGLVGDRLPAAALDTAQDSVGGGLAV FT AGRLATDPAAGPEQAQALADAVNKAFAHGVSTTSLVGGVIMAAGTLIVLAVLPGRRARA FT QQAEDAREPEYSGAAS" FT CDS complement(240489..241343) FT /transl_table=11 FT /gene="SCO5958" FT /gene_synonym="cbiO" FT /product="cobalt transport system ATP binding protein" FT /note="SC7H1.28c, cbiO, probable cobalt transport system FT ATP binding protein, len: 284 aa; similar to many eg. FT CBIO_SALTY Q05596 cobalt transport ATP-binding protein (271 FT aa), fasta scores; opt: 567 z-score: 685.3 E(): 5.6e-31, FT 38.8% identity in 242 aa overlap. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop) and Pfam match to FT entry ABC_tran PF00005, ABC transporters, score 203.07" FT /db_xref="GOA:O54187" FT /db_xref="InterPro:IPR005876" FT /db_xref="UniProtKB/Swiss-Prot:O54187" FT /protein_id="CAA16215.1" FT /translation="MSEPAQPSEPAPALVALRGAAFAYEEGPDVLTGLDFAVREGRALA FT LLGRNGSGKTTLMRLLSGGLKPHTGTLTLGGEPVAYDRKGLTRLRTTVQLVVQDPDDQL FT FAASVGQDVSFGPLNLGLSDAEVRSRVGEALAALDISGLAERPTHLLSYGQRKRTAIAG FT AVAMRPRVLILDEPTAGLDPDGQERLLATLDGLRAGGTTVVMATHDVDLALRWSDDAAL FT LTPEGVRTGPTAATLARTDLLRRAGLRLPWGVAATGLLRARGLLADSATGPRTAEELAA FT LAE" FT misc_feature complement(240666..241223) FT /note="Pfam match to entry ABC_tran PF00005, ABC FT transporters, from 1 to 192, score 203.07" FT misc_feature complement(241179..241202) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(241340..242089) FT /transl_table=11 FT /gene="SCO5959" FT /gene_synonym="cbiQ" FT /product="cobalt transport integral membrane protein" FT /note="SC7H1.29c, cbiQ, probable cobalt transport integral FT membrane protein, len: 249 aa; similar to eg. CBIQ_SALTY FT Q05598 cobalt transport protein cbiq (225 aa), fasta FT scores; opt: 182 z-score: 241.4 E(): 3e-06, 28.1% identity FT in 228 aa overlap" FT /db_xref="GOA:O54188" FT /db_xref="InterPro:IPR012809" FT /db_xref="UniProtKB/TrEMBL:O54188" FT /protein_id="CAA16216.1" FT /translation="MLPIDAAAHGSRWRRRHPVDKAVLGLGLTVLAISLPPWPGAALVL FT VAALTVLLGPAGVPGRRLWRAYRVPLGFCVTGALPLLVQVGGPDGFLTAADGGAVRAGG FT LLLRTSAASLGVLLFAFTTPMSDLLPRLVRAGVPAPVVDVALVTYRMSFLLLDSVRRIR FT QAQAARLGHTTRAAAWRSLGGLGATAFVRAFDRAARLQSGLAGRGYDGTLRVLVPEARV FT SVPFTAASVALLAALAALTLVLEGPLS" FT RBS complement(241352..241356) FT /note="possible RBS upstream of cbiO" FT CDS complement(242090..242446) FT /transl_table=11 FT /gene="SCO5960" FT /gene_synonym="cbiN" FT /product="puative cobalt transport protein" FT /note="SC7H1.30c, cbiN, probable cobalt transport protein, FT len: 118 aa; similar to many eg. CBIN_SALTY Q05595 cobalt FT transport protein cbin (93 aa), fasta scores; opt: 283 FT z-score: 433.7 E(): 5.8e-17, 47.3% identity in 93 aa FT overlap. Contains possible N-terminal signal sequence" FT /db_xref="GOA:O54189" FT /db_xref="InterPro:IPR003705" FT /db_xref="UniProtKB/Swiss-Prot:O54189" FT /protein_id="CAA16217.1" FT /translation="MSRNTRINALLLLAVAALAVLPLVLGLGDHKEEPFAGADAEAETA FT ITEIEPDYEPWFSPLHEPPSGEVESALFALQAALGAGVLAYYFGLRRGRRQGEERASAA FT SGAAAAPGDAPEGD" FT RBS complement(242097..242100) FT /note="possible RBS upstream of cbiQ" FT CDS complement(242443..243216) FT /transl_table=11 FT /gene="SCO5961" FT /gene_synonym="cbiM" FT /product="puative cobalt transport protein" FT /note="SC7H1.31c, cbiM, probably involved in cobalt FT transport, len: 257 aa; similar to many eg. CBIM_SALTY FT Q05594 cbim protein. salmonella typhimurium. (245 aa), FT fasta scores; opt: 749 z-score: 1155.1 E(): 0, 53.6% FT identity in 224 aa overlap. Contains PS00402 FT Binding-protein-dependent transport systems inner membrane FT component signature" FT /db_xref="GOA:O54190" FT /db_xref="InterPro:IPR018024" FT /db_xref="UniProtKB/TrEMBL:O54190" FT /protein_id="CAA16218.1" FT /translation="MVPVSQETGQGASSIHEVLERVCRVMHIAEGFLPPAHAIAWGVAS FT APFVVHGVRSLTREVREHPESTLLLGASGAFTFVLSALKLPSVTGSCSHPTGTGLGAIL FT FRPPIMAVLGTITLLFQALLLAHGGLTTLGANVFSMAIVGPWAGYGVYRLLRRWDVPLM FT VTVFFGAFVADLSTYCVTSVQLALAFPDPSSGFLGALGKFGSIFAVTQIPLAVSEGLLT FT VIVMRLLVQSSKGELTRLGVLLTRTGERKQEAVAR" FT RBS complement(242451..242455) FT /note="possible RBS upstream of cbiN" FT misc_feature complement(242965..243051) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane component signature" FT RBS complement(243225..243228) FT /note="possible RBS upstream of cbiM" FT CDS complement(243428..244018) FT /transl_table=11 FT /gene="SCO5962" FT /gene_synonym="SC7H1.32c" FT /product="putative transcriptional regulator" FT /note="SC7H1.32c, probable transcriptional regulator, MerR FT family; len: 196 aa; similar to many eg. NOLA_BRASN P50330 FT nodulation protein nola. bradyrhizobium japonicum (237 aa), FT fasta scores; opt: 282 z-score: 360.0 E(): 7.4e-13, 34.6% FT identity in 159 aa overlap. Contains PS00552 Bacterial FT regulatory proteins, merR family signature, FT Helix-turn-helix motif at aa 10-31, Score 1627 (+4.73 SD), FT and Pfam match to entry merR PF00376, Bacterial regulatory FT proteins, merR family, score 92.85" FT /db_xref="GOA:O54191" FT /db_xref="HSSP:1Q06" FT /db_xref="InterPro:IPR015358" FT /db_xref="UniProtKB/TrEMBL:O54191" FT /protein_id="CAA16219.1" FT /translation="MTHATDGSRHIGALARETGLSIRTLRYYDRLGLLTPSARTEGGHR FT CYDAGDVRRLHRVLALRSFGLPLARIRAVLDAEPDHDPAELIRRQLDVVEERLRQTAEL FT RIRLLGVLGALDAAADGSTEALLDVIEEMTAVTRPLTPEQVAGLGEARRRWAESLGEEE FT LRALHHRRAEIFATMGEDDRRRLTDRRRRALAP" FT misc_feature complement(243794..243988) FT /note="Pfam match to entry merR PF00376, Bacterial FT regulatory proteins, merR family, from 1 to 65, score FT 92.85" FT misc_feature complement(243917..243985) FT /note="PS00552 Bacterial regulatory proteins, merR family FT signature" FT RBS complement(244025..244030) FT /note="possible RBS upstream of SC7H1.32c" FT CDS complement(244083..244658) FT /transl_table=11 FT /gene="SCO5963" FT /gene_synonym="SC7H1.33c" FT /product="putative membrane protein" FT /note="SC7H1.33c, possible membrane protein, len: 191; FT Contains PS00044 Bacterial regulatory proteins, lysR family FT signature, though this may be spurious" FT /db_xref="InterPro:IPR013099" FT /db_xref="UniProtKB/TrEMBL:O54192" FT /protein_id="CAA16220.1" FT /translation="MKDRRTAHPRPRPRTPPRRRTGWDAVGPWVVRAGIAAAVVVAYFL FT LPLDHLGPQRPVLSWVLFALLLTVVAVLLLRQIRHVLLDRPDSRPGVVISLLIVLSVHV FT FSAAYYALAKSPGEFNGLHTRIDALYFTVVTLATVGYGDITPRGQAARVVTVLQITYSF FT VFLTAAATALTTRMRDRVVRGPQRGRSR" FT misc_feature complement(244176..244253) FT /note="PS00044 Bacterial regulatory proteins, lysR family FT signature" FT CDS complement(244655..246013) FT /transl_table=11 FT /gene="SCO5964" FT /gene_synonym="SC7H1.34c" FT /product="putative membrane protein" FT /note="SC7H1.34c, probable membrane protein, len: 452 aa; FT contains PS00142 Neutral zinc metallopeptidases, FT zinc-binding region signature. Contains possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:O54193" FT /db_xref="InterPro:IPR006025" FT /db_xref="UniProtKB/TrEMBL:O54193" FT /protein_id="CAA16221.1" FT /translation="MTAPANAVPDRAERSLRQTLLSPGYRRLLLLCVLLGVPIALACFF FT FVGLQHELQHWVWTSLPEAAGYDTPPWWWPLPALVLAGLILAPIVTRMPGGGGHLPVNG FT LGGAPVGPRALPGAVLAALATLPLGVVLGPEAPLMAVGSGLALLAVRRAGAGGDQQASA FT ILATAGSTAAISTILGGPIAAAVLLIEGAGLAGTQLVALLLPCLLASATGALVFTGFGQ FT WTGLEIGALSLPDLPPQANPDAGDFLWGLPTAALIAVLVTLARALGRRTVSWTRHRTAA FT RTVACATAVGVCVAAYALITGRSPAEAALSGQATLAQLAAHPHAWSVGALVALVACKGL FT AWGIALGALRGGPIFPAVLLGAATALACSGLPGFGATPALALGIAAAAAAVTGLPLASS FT VLAVLLMGRDSHDQMPLIVMASVVAFVVAQLVRRTPPEAGGSPGGAPSAGAAR" FT RBS complement(244666..244669) FT /note="possible RBS upstream of SC7H1.33c" FT misc_feature complement(245843..245872) FT /note="PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature" FT RBS 246288..246292 FT /note="possible RBS upstream of SC7H1.35" FT CDS 246301..246768 FT /transl_table=11 FT /gene="SCO5965" FT /gene_synonym="SC7H1.35" FT /product="putative integral membrane protein" FT /note="SC7H1.35, possible integral membrane protein, len: FT 155 aa; weakly similar to hypothetival proteins from FT Archaeoglobus fulgidus and Mycobacterium leprae e.g. FT TR:G2650576 (EMBL:AE001101) AF0081 hypothetical 17.4 kd FT protein from Archaeoglobus fulgidus (156 aa), fasta scores; FT opt: 129 z-score: 186.3 E(): 0.0035, 28.7% identity in 101 FT aa overlap and similar to TR:O86494 (EMBL:AL031232) FT Streptomyces coelicolor putative integral membrane protein FT SC10H5.02c, 151 aa; fasta scores: opt: 431 Z-score: 491.5 FT E(): 9.6e-20; 53.509% identity in 114 aa overlap. Contains FT possible hydrophobic membrane spannig regions" FT /db_xref="UniProtKB/TrEMBL:O54194" FT /protein_id="CAA16222.1" FT /translation="MSQHAEPSPGRPSHGGDASWAQRSGDRTSGWVTGGVVFAGVLLLL FT NGALAVLQGIAAIAEDDVYARIGTYVYEMSLTGWGIVHVILGALVFVTGFGLLKDMAWA FT RVAGIVLASLSLIAQFLFLPYAPVWSVIMMAIDVFVIWALASRQDSASSRA" FT stem_loop 246847..246911 FT /note="hairpin loop with 19 bp stem" FT CDS complement(246912..250055) FT /transl_table=11 FT /gene="SCO5966" FT /gene_synonym="StBAC16H6.01c" FT /gene_synonym="SC7H1.36c" FT /product="putative oxidase" FT /note="SCBAC16H6.01c, possible oxidase, len: >1032aa: FT similar to many of undefined function eg. TR:Q9EZK2 FT (EMBL:AF289509) putative oxidase YdiJ-like protein from FT Pseudomonas putida (1006 aa) fasta scores; opt: 880, FT Z-score: 889.5, 27.930% identity (31.672% ungapped) in 1024 FT aa overlap and TR:Q9F2Y0 (EMBL:AL392149) putative FT oxidoreductase SCD19.22 from Streptomyces coelicolor (951 FT aa) fasta scores; opt: 622, Z-score: 628.7, 49.698% FT identity (53.813% ungapped) in 994 aa overlap. Contains FT Prosite match to PS00198 4Fe-4S ferredoxins, iron-sulfur FT binding region signature; Pfam match to entry PF02913 FT FAD-oxidase_C, FAD linked oxidases, C-terminal domain and FT Pfam match to entry PF01565 FAD_binding_4, FAD binding FT domain." FT /note="SC7H1.36c, unknown, partial CDS, len: >81 aa" FT /db_xref="GOA:Q8CJQ0" FT /db_xref="InterPro:IPR006094" FT /db_xref="UniProtKB/TrEMBL:Q8CJQ0" FT /protein_id="CAD55242.1" FT /translation="MGALDLPEPVTREGAPPKVDTAALRDALRERVDGEVRFDAGSRAA FT YSTDASNFRQTPLGVVVPRTPEAGVEAVAVAREFGAPVLSRGGGTSLAGQCTNAGVVLD FT WSKYCTRVESVDPGARTCVVQPGIVLDDLNRQLAPHGLRYGPEPATHPNCTIGGMIGNN FT SCGATAQAHGKVVDNIARLEVLLYDGTRFWCGETDDEEYAEIERQGDLRATVYRRLRAL FT RDTYGDEIRRRFPDVPRRVSGYNLDSLLPEFGFDVAGLLVGSESTLVTVVRAELELVPV FT VRERSLLVLGFDSIDKAADAVPDILPHEPIALEGVDARLVRDERIKHLNPEALAEMPEG FT NAYLMVQFGGDTVEEADARAHRMLEAVHRSEHDADCAFLDDPSHEEDLWQVREAGLGAT FT AHIPGKPDTFEGWEDSAVSPEKLGDYLRRLRGLFEEFGYLSDTGPSLYGHFGQGCVHTR FT IPFDLYTADGVATYRRFMERAADLVVEFGGSLSGEHGDGQSRGELLGRMYGDRLVEAFG FT RLKAVFDPLDRMNPGKVVAPYGLDDNLRLGGDWAPFEPRDLHFRFPHDGGSFSQAANRC FT VGVGKCRQHTSDGTVMCPSYQVTREEEHSTRGRARLLFEMLDGHGDGAIRDGWRSQEVK FT DALDLCLACKGCKKDCPADVDMATYKAEFLSHHYERRPWRRPRSDWSMGWLPALAQVVG FT RTRLAPVVNALTHAPLLSKAAVLVAGVADREVPLFADETFERWFAEHEPEGDGRRGSVL FT LWPDTFTNHFHPHIGRAAVRVLEQAGWRVELPHEPLCCGLTWVSTGQLGTAERVLTRTV FT RALAGHVRSGGLVVALEPSCTAVFRADAKELFPGDQDVLRLAEQTVTLSELLTEHSPGY FT EPPRVPERSARAVAQVHCHQHAVLGWEADRELLRRAGVDAERLDSGCCGLAGNFGFERG FT HLDVSEACAERVLLPRLREEDESTVVLADGFSCRTQIHEFDSGGHEGVHLAELLASALP FT PGPATEPGAPGSAYGTAPGARPAAPGPRARALALAGTAAAAVGAAAAATALARSLRRH" FT misc_feature complement(248100..248135) FT /note="PS00198 4Fe-4S ferredoxins, iron-sulfur binding FT region signature" FT misc_feature complement(248454..249251) FT /note="Pfam match to entry PF02913 FAD-oxidase_C, FAD FT linked oxidases, C-terminal domain, score 53.70, E-value FT 4e-12" FT misc_feature complement(249255..249980) FT /note="Pfam match to entry PF01565 FAD_binding_4, FAD FT binding domain, score 144.80, E-value 1.5e-39" FT CDS 250260..250670 FT /transl_table=11 FT /gene="SCO5967" FT /gene_synonym="SCBAC16H6.02" FT /product="conserved hypothetical protein" FT /note="SCBAC16H6.02, conserved hypothetical protein, len: FT 136aa: similar to many eg. TR:Q9EWX7 (EMBL:AL445403) FT conserved hypothetical protein 2SCI34.02 from Streptomyces FT coelicolor (146 aa) fasta scores; opt: 257, Z-score: FT 325.1, 41.667% identity (43.269% ungapped) in 108 aa FT overlap." FT /db_xref="GOA:Q93JG0" FT /db_xref="InterPro:IPR007561" FT /db_xref="UniProtKB/Swiss-Prot:Q93JG0" FT /protein_id="CAC44581.1" FT /translation="MKSGEPVNSHDVTDEQWEGLAQVVPLRGRDAWPSAVGHRAMPEAE FT TERRRRFVVLRINVFADAREVAETLMAGIPVLLDLTSAEGEVAKRVLDFSTGVVFGLAS FT GMHRVDRNVFLLTPAGTEVNGLMESAAGVPGV" FT CDS 250766..251974 FT /transl_table=11 FT /gene="SCO5968" FT /gene_synonym="StBAC16H6.03" FT /product="putative bldA-regulated nucleotide binding FT protein" FT /note="SCBAC16H6.03, possible bldA-regulated nucleotide FT binding protein, len: 402aa: no significant database FT matches. Contains TTA-encoded leucine close to N-terminus - FT possible target for bldA regulation. Also contains Prosite FT match to PS00017 ATP/GTP-binding site motif A (P-loop)." FT /db_xref="InterPro:IPR018524" FT /db_xref="UniProtKB/TrEMBL:Q93JF9" FT /protein_id="CAC44582.1" FT /translation="MAASSASSALPASVAPVPDRPRITQLRLSAFAGHRRAVLRLGPLT FT VLAGPSGSGKTSALRAYDALARLGGGAELGAVFPDPGACVPERARPDAQHRRGFRIGCT FT ADGAEGPVHLDVAVQAEPELRIVGERLTADGVVLLETALRDPGRRAVQAAWHTAGSAPV FT TRAPLPDDRLGTPLLPLRVAGKTDGQRRVLAAAEQMVVALRSVFACDPRPGRMREPVPT FT GSGRLLGGCDNLADVLWRTRAECGRRHAQFVAAVRAGCAGPVEDVLAEPALGGVVGALL FT DRGDGVRTGLGRLGYGELRFLALALVLFTGPGVLEVDPAGEVPAALQTLTVLADGFDRG FT LDVRQRAELLRLAARMCDRGHIRLVAAVADASWAVEAVEAVGEAGQAGAAAAGGVTVVH FT LSP" FT misc_feature 250793..250795 FT /note="TTA codon encoding leucine - possible target for FT bldA regulation." FT misc_feature 250910..250933 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 251971..252324 FT /transl_table=11 FT /gene="SCO5969" FT /gene_synonym="StBAC16H6.04" FT /product="conserved hypothetical protein" FT /note="SCBAC16H6.04, conserved hypothetical protein, len: FT 402aa: similar to many eg. TR:Q9K5U1 (EMBL:AP001520) BH3997 FT protein from Bacillus halodurans (101 aa) fasta scores; FT opt: 282, Z-score: 358.7, 40.196% identity (42.268% FT ungapped) in 102 aa overlap." FT /db_xref="InterPro:IPR004518" FT /db_xref="UniProtKB/TrEMBL:Q93JF8" FT /protein_id="CAC44583.1" FT /translation="MTDHPRDLAALRRRLAEFAAARDWQPYHTPKNLAAALSVEASELL FT EIFQWLTPEQSARVMTDPDTAHRVRDEVADVLAYLLQFCEVLGVDPLAALEEKIERNES FT RFPVAGEVGRPEG" FT CDS 252507..252977 FT /transl_table=11 FT /gene="SCO5970" FT /gene_synonym="StBAC16H6.05" FT /product="hypothetical protein" FT /note="SCBAC16H6.05, unknown, len: 156 aa: no significant FT database matches. Contains TTA-encoded leucine close to FT C-terminus." FT /db_xref="UniProtKB/TrEMBL:Q93JF7" FT /protein_id="CAC44584.1" FT /translation="MDAVRLIVTSGRALAAGGEVPEVLTEVWQVQALAQAIGSRLAVHG FT PPELRGEAIGLTELAGRGCGVLHTPELAPGELRAAQLTELGDARQALMRLGTLLGETGI FT ALVGVACAADDEATYWQCMEAIDAADESRDRVLEMLRKLADRDAHLPEREAG" FT misc_feature 252954..252956 FT /note="TTA codon encoding leucine - possible target for FT bldA regulation." FT misc_feature 253306..254223 FT /note="Pfam match to entry PF00296 bac_luciferase, FT Bacterial luciferase, score -9.40, E-value 1.2e-06" FT CDS 253306..254229 FT /transl_table=11 FT /gene="SCO5971" FT /gene_synonym="StBAC16H6.06" FT /product="conserved hypothetical protein" FT /note="SCBAC16H6.06, conserved hypothetical protein, len: FT 307 aa: similar to many e.g. TR:AAK45058 (EMBL:AE006971) FT hypothetical protein from Mycobacterium tuberculosis (347 FT aa) fasta scores; opt: 482, Z-score: 543.4, 32.399% FT identity (37.011% ungapped) in 321 aa overlap. Contains FT Pfam match to entry PF00296 bac_luciferase, Bacterial FT luciferase" FT /db_xref="GOA:Q93JF6" FT /db_xref="InterPro:IPR019952" FT /db_xref="UniProtKB/TrEMBL:Q93JF6" FT /protein_id="CAC44585.1" FT /translation="MDLRIFTEPQQGATYDTLLTVAKATEDLGFDAFFRSDHYLRMGAA FT DGLPGPTDAWITLAGLARETKRIRLGTLMTAGTFRLPGVLAIQVAQVDQMSGGRVELGL FT GAGWFEEEHKAYGIPFPKEKIGRLEEQLAIVTGLWATETGKTFDFHGKFYDLTDSPALP FT KPAQAKVPVLIGGHGATRTPRLAGQYADEFNMPFASIEDTERQFGRVRAAAEAAGRAAD FT ALTYSNALVACVGKDDAEVARRAAVIGREVEELKANGLAGSPAEVVEKIGRYAEAGAQR FT IYLQILDLDDLDHLELISSQVQAQLS" FT CDS 254305..255900 FT /transl_table=11 FT /gene="SCO5972" FT /gene_synonym="StBAC16H6.07" FT /product="hypothetical protein" FT /note="SCBAC16H6.07, hypothetical protein with conserved FT region, len: 307aa: 300-500 aa region similar to many eg. FT TR:Q9V662 (EMBL:AE003823) CG12367 protein from Drosophila FT melanogaster (309 aa) fasta scores; opt: 294, Z-score: FT 338.2, 34.194% identity (37.324% ungapped) in 155 aa FT overlap." FT /db_xref="InterPro:IPR013217" FT /db_xref="UniProtKB/TrEMBL:Q93JF5" FT /protein_id="CAC44586.1" FT /translation="MTVVLPEPSGYRPGGSRAYGVPSRPPAGEALRMFLTLTTTGTPEH FT PATDLGFLLHKHPEKAQAFSTSFGTAHVLYPEAEDQRCTAALLLEVDAVALVRRGKGKG FT RGGAPDAALAQYVNDRPYAASSLLAVALSSVFSSAMRGVCKSRPERAAESLPLRVEIPA FT LPARGGPDLVRRLFEPLGWTVDVEAVPLDTAFPEWGDSRYVRLVLESETLTLSNALRHL FT YVLLPVLDDAKHYWVAPDEVDKLLRAGAGWLPGHPEHKLITSRYLSRRWSLTREAMDRL FT ELIRLAETDDSEVEEIDNAVEAEAEQEPKPTPLAVHRREAILTALRDHAAARVLDLGCG FT EGHLVRELLREPRFTEIVGVDVSVRALTIASRRLKLDRMGERQAARVRLFQGSLAYTDK FT RLKGYDAAVLSEVIEHLDLPRLPALEYAVFGSARPRTVVVTTPNVEYNVRWETLPAGHV FT RHRDHRFEWTRGEFRAWAGAVAERHGYDVEFRPVGPDDPEVGPPTQLALFTLRTITETP FT ATTATATEKEAKAA" FT CDS 255981..258509 FT /transl_table=11 FT /gene="SCO5973" FT /gene_synonym="StBAC16H6.08" FT /product="putative phosphatase" FT /note="SCBAC16H6.08, possible phosphatase, len: 842 aa: FT similar to TR:O69213 (EMBL:AJ224354) protein FT serine-threonine phosphatase from Anabaena sp. (strain PCC FT 7120) fasta scores; opt: 2173, Z-score: 2321.6, 52.962% FT identity (54.808% ungapped) in 861 aa overlap. Contains FT Prosite match to PS00017 ATP/GTP-binding site motif A FT (P-loop)." FT /db_xref="GOA:Q93JF4" FT /db_xref="InterPro:IPR004843" FT /db_xref="UniProtKB/TrEMBL:Q93JF4" FT /protein_id="CAC44587.1" FT /translation="MRARALPVTDLSLVVLIGASGSGKSTFARRHFTPTEVISSDFCRG FT LVADDENDQSASRDAFDVLHYIAGKRLAAGRRTVVDATNVQQDARRQLIELARKHDVLP FT IAIVLDVPEQVCAERNATRSDRADMPRRVIQRHTRELRRSLRHLEREGFRKVHVLRGTA FT EAEHATVVTEKRFNDLTHLTGPFDIVGDIHGCAAELETLLGKLGYTDGVHPDGRTAVFV FT GDLVDRGPDSPGVLRRVMSMVKSGNALCVPGNHENKYGRFLKGRKVQHTHGLAETVEQM FT DGESEEFRAEVREFIDSLVSHYVLDGGRLVVCHAGLPEKYHGRTSGRVRSHALYGDTTG FT ETDEFGLPVRYPWAEDYRGRAAVVYGHTPVPEATWLNNTICLDTGAVFGGRLTALRWPE FT REIVDVPAERVWYEPAKPLRTEAPGGHDGRPLDLADVQGRRVVETRHAGRITVREENGA FT AALEVMSRFATDPRLLPYLPPTMAPTATSGVDGYLEHPKEAFAQYAADGVARVVCEEKH FT MGSRAVALVCRDADAARTRFGVDGPTGSLYTRTGRPFLDDASVTEEILDRLRTAIGEAG FT LWDELATDWLLLDTELMPWSLKASGLLRSQYAAVGAASGAVFPGALAALEGAAARGVAV FT KDLLDRQRARSADAAAFTDAYRRYCWPTEGLDGVRLAPFQILAVQGRSLAALPHDEQLA FT LLDRLVEHDGSGLLQTTRRLYVDTGDPESVSAGVDWWLEMTGRGGEGMVVKPVGALVRD FT DKARLVQPGIKCRGREYLRIIYGPEYTRPDNLARLRHRFLNHKRSLAVREYALGLEALD FT RLADGEPLWRVHEAVFGVLALESEPVDPRL" FT misc_feature 256032..256055 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(258561..259856) FT /transl_table=11 FT /gene="SCO5974" FT /gene_synonym="StBAC16H6.09c" FT /product="putative integral membrane ion exchanger" FT /note="SCBAC16H6.09c, possible integral membrane ion FT exchanger, len: 431 aa: similar to many eg. TR:Q9LUN4 FT (EMBL:AB022219) Na+/H+ exchanging protein-like from FT Arabidopsis thaliana (800 aa) fasta scores; opt: 667, FT Z-score: 684.9, 34.048% identity (35.572% ungapped) in 420 FT aa overlap. Contains Pfam match to entry PF00999 FT Na_H_Exchanger, Sodium/hydrogen exchanger family and FT multiple possible membrane-spanning hydrophobic regions." FT /db_xref="GOA:Q93JF3" FT /db_xref="InterPro:IPR006153" FT /db_xref="UniProtKB/TrEMBL:Q93JF3" FT /protein_id="CAC44588.1" FT /translation="MSPDALITHFVGASALILVAAHSGGWLARRLGQPYIVGQLATGIA FT LGPSLLGSMAPDAYAALFPAAIGPALTGLAQFSLVVFLFAVGYELDLKMLGVRARSSVN FT VALASFAVPMAVGSGCALLFGDALHDLGMPGDLSPGMVVFAGVALATTAVPVLTAIVRE FT NGLSRTVPGVVAVSAAGVLDAICWTVLAGALLEAGGGDGAGGGLGWPWRVLLTVGYVAL FT MACAARPLLRLLLWRTRLEPSLRMALLIGFALGSAWVTHALGLHVIFGALLAGVVVPRE FT AGGTLDPDLLRPLLSVASLLLPFFFVLSGQSVALNSMTGTGWAALAVVTLLAVVTKIGS FT GAAAAGLGGLDRHDAWTVGILLNTRGLTELIALNAGLDAGLLSAPLYTVLVFMALATTL FT LTQPLLLLNARLATRERRPESARSTAVKPYAG" FT misc_feature complement(258597..259838) FT /note="Pfam match to entry PF00999 Na_H_Exchanger, FT Sodium/hydrogen exchanger family, score 10.80, E-value FT 2.4e-05" FT CDS 260048..261304 FT /transl_table=11 FT /gene="SCO5975" FT /gene_synonym="arcA2" FT /gene_synonym="StBAC16H6.10" FT /product="arginine deiminase" FT /EC_number="3.5.3.6" FT /note="SCBAC16H6.10, arcA2, arginine deiminase, len: 418 FT aa: similar to many e.g. SW:Q9RJN1 (ARCA_STRCO) arginine FT deaminase ArcA SCF55.37 from Streptomyces coelicolor (420 FT aa) fasta scores; opt: 1124, Z-score: 1310.8, 43.350% FT identity (43.781% ungapped) in 406 aa overlap and SW:O31017 FT (ARCA_RHIET) arginine deaminase from Rhizobium etli (409 FT aa) fasta scores; opt: 1153, Z-score: 1344.7, 45.854% FT identity (47.000% ungapped) in 410 aa overlap. Contains FT Pfam match to entry PF02726 Arg_deiminase, Arginine FT deiminase." FT /db_xref="GOA:Q93JF2" FT /db_xref="HSSP:1RXX" FT /db_xref="InterPro:IPR003876" FT /db_xref="UniProtKB/TrEMBL:Q93JF2" FT /protein_id="CAC44589.1" FT /translation="MNGRRSGQDGDMGFQVDSEAGRLTRVILHRPDLELKRLTPSNKDA FT LLFDDVLWVRRARAEHDGFADVLRDRGVAVHLFGDLLTETLDVPAARRLVLDRVFDEKE FT YGVLATDHLRAAFETLPAHELAEWLVGGMTKREFLDAHPEPTSVRFHAMELDDFLLGPL FT PNHLFTRDTSAWIYDGVSINAMRWPARQRETVHFEAIYRHHPLFRDESFHLWSEGQADY FT PSTIEGGDVLVIGNGAVLIGMSERTTPQAVEMLAHKLFAAGSARTIVALDMPKRRAFMH FT LDTVMTMVDGDTFTQYAGLGMLRSYTIEPGAGEKDLKVTDHPPEHMHRAMAAALGLGEI FT RVLTATQDVHAAEREQWDDGCNVLAVEPGVVVAYERNATTNTHLRKQGIEVIEIPGSEL FT GRGRGGPRCMSCPVERGPV" FT misc_feature 260714..261295 FT /note="Pfam match to entry PF02726 Arg_deiminase, Arginine FT deiminase, score 312.40, E-value 5.4e-90" FT CDS 261399..262406 FT /transl_table=11 FT /gene="SCO5976" FT /gene_synonym="arcB" FT /gene_synonym="StBAC16H6.11" FT /product="ornithine carbamoyltransferase" FT /EC_number="2.1.3.3" FT /note="SCBAC16H6.11, arcB, ornithine carbamoyltransferase, FT len: 335 aa; similar to many e.g. SW:O31018 (OTCC_RHIET) FT ornithine carbamoyltransferase from Rhizobium etli (334 aa) FT fasta scores; opt: 1401, Z-score: 1585.7, 64.024% identity FT (64.220% ungapped) in 328 aa overlap. Contains Pfam match FT to entry PF02729 OTCace_N, Aspartate/ornithine FT carbamoyltransferase, carbamoyl-P binding domain; Pfam FT match to entry PF00185 OTCace, Aspartate/ornithine FT carbamoyltransferase, Asp/Orn binding domain and Prosite FT match to PS00097 Aspartate and ornithine FT carbamoyltransferases signature" FT /db_xref="GOA:Q93JF1" FT /db_xref="HSSP:1DXH" FT /db_xref="InterPro:IPR002292" FT /db_xref="UniProtKB/Swiss-Prot:Q93JF1" FT /protein_id="CAC44590.1" FT /translation="MATVPTALAGRHFLKELDFTEEEFRGLIELAAELKAAKRAGTETR FT YLQGRNIALIFEKTSTRTRCAFEVAAADQGASTTYLDPAGSQIGHKESVKDTARVLGRM FT FDGIEYRGDSQTKVEELAAFAGVPVYNGLTDDWHPTQMLADVLTMTEHSDRPLREITFA FT YLGDARFNMGNSYLVTGALLGMDVRIVAPKSYWPAQEVVDRAHRLAAASGARITLTEDV FT AEGVRGAGFVVTDVWVSMGEPKEVWAERIKALAPYAVTMDVLRATGNPDVRFLHCLPAF FT HDLGTKVGQEIFEAHGLDSLEVTDEVFESAHSVVFDEAENRLHTIKAVLVATLA" FT misc_feature 261429..261857 FT /note="Pfam match to entry PF02729 OTCace_N, FT Aspartate/ornithine carbamoyltransferase, carbamoyl-P FT binding domain, score 250.50, E-value 2.2e-71" FT misc_feature 261564..261587 FT /note="PS00097 Aspartate and ornithine FT carbamoyltransferases signature" FT misc_feature 261867..262400 FT /note="Pfam match to entry PF00185 OTCace, FT Aspartate/ornithine carbamoyltransferase, Asp/Orn binding FT domain, score 289.40, E-value 1.3e-84" FT CDS 262536..263975 FT /transl_table=11 FT /gene="SCO5977" FT /gene_synonym="StBAC16H6.12" FT /product="putative amino acid permease" FT /note="SCBAC16H6.12, possible amino acid permease, len: FT 479aa: similar to many eg. SW:O43246 (CTR4_HUMAN) cationic FT amino acid permease from Homo sapiens (636 aa) fasta FT scores; opt: 704, Z-score: 760.9, 33.679% identity FT (34.946% ungapped) in 386 aa overlap and TR:Q9L100 FT (EMBL:AL159139) putative amino acid permease SCL6.16c from FT Streptomyces coelicolor (496 aa) fasta scores; opt: 1575, FT Z-score: 1699.3, 53.377% identity (53.493% ungapped) in 459 FT aa overlap. Contains Pfam match to entry PF00324 FT aa_permeases, Amino acid permease and possible FT membrane-spanning hydrophobic regions." FT /db_xref="GOA:Q93JF0" FT /db_xref="InterPro:IPR004841" FT /db_xref="UniProtKB/TrEMBL:Q93JF0" FT /protein_id="CAC44591.1" FT /translation="MPASRVKSPHLLVAESGADREGHGLKRTMGLFQLVCFGVGAIVGT FT GIFVGLSDSVAEAGPAVVVSFVLAAITCVFTAFAFAELGGAIPVSGSSYSFAYAGLGER FT TAFLVGWCLLLEYGVSVSAVAVGWSQYVNELLDTVLGVQLPHALSAGPGDGGAVNLPAV FT VVIALASVLLMRGVRESARATAAMAVLKLAVLLAFCAIGFYAFQDGNLTPFSPAGLGGI FT GAGTTAAFFSYIGFDAITTAGEEAKNPRRDIPVAILVCIGLVTLLYCAVAVAAIGAVGG FT DQVGNRPAALSYVVDRVTGSAIGGGVVAFGAVVAIASVVLAVMYGQTRILMSMSRDGLI FT PRVFEKVSPRTATPVAGTLIVGVVFALPAAFAPLDAVVNLCTIGTLATMAAVNVSVITL FT RRREPGLARTFRVPLYPATPLLGVGFCLYLMYETGGATWLQFAVFLAVGLLVYSAYGRR FT HSRLARTAVSADDAERVPQEA" FT misc_feature 262608..263909 FT /note="Pfam match to entry PF00324 aa_permeases, Amino acid FT permease, score -58.70, E-value 2.1e-10" FT CDS complement(263935..264420) FT /transl_table=11 FT /gene="SCO5978" FT /gene_synonym="StBAC16H6.13c" FT /product="conserved hypothetical protein" FT /note="SCBAC16H6.13c, conserved hypothetical protein, len: FT 161aa: similar to many others in Streptomyces coelicolor FT eg. TR:Q9X7Q5 (EMBL:AL049587) hypothetical protein FT SC5F2A.32 (161 aa) fasta scores; opt: 222, Z-score: 255.7, FT 32.515% identity (36.054% ungapped) in 163 aa overlap. Also FT similar to TR:O69204 (EMBL:U33059) hypothetical protein FT from Actinosynnema pretiosum (subsp. auranticum) (144 aa) FT fasta scores; opt: 227, Z-score: 261.8, 39.735% identity FT (45.113% ungapped) in 151 aa overlap. Contains Pfam match FT to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase FT B-, phytochrome-like ATPase." FT /db_xref="GOA:Q93JE9" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q93JE9" FT /protein_id="CAC44592.1" FT /translation="MKAGQDSPAPRNGPAVHDHFPAPASWRIALPHSAAAVPVARALVR FT NALAELEHTADGDTAELLTAELVANAVEHTPAGPTAIELVVELMPTGCQVEVHDPDPSP FT PADLTRPDVEPPDPWREDGRGLLLIRALSSSCGHRPTRSGKAVWFRLPAVPAQRRPH" FT misc_feature complement(264124..264258) FT /note="Pfam match to entry PF02518 HATPase_c, Histidine FT kinase-, DNA gyrase B-, phytochrome-like ATPase, score FT 14.30, E-value 0.014" FT CDS 264552..265379 FT /transl_table=11 FT /gene="SCO5979" FT /gene_synonym="StBAC16H6.14" FT /product="putative enoyl-CoA hydratase" FT /note="SCBAC16H6.14, possible enoyl-CoA hydratase, len: 275 FT aa: similar to many e.g. SW:P77467 (PAAG_ECOLI) probable FT enoyl-CoA hydratase from Escherichia coli (262 aa) fasta FT scores; opt: 488, Z-score: 554.6, 36.434% identity FT (37.450% ungapped) in 258 aa overlap and TR:Q9AJT1 FT (EMBL:AJ278289) hypothetical protein from Thauera aromatica FT (272 aa) fasta scores; opt: 780, Z-score: 880.5, 44.318% FT identity (44.656% ungapped) in 264 aa overlap. Contains FT Pfam match to entry PF00378 ECH, Enoyl-CoA FT hydratase/isomerase family and Prosite match to PS00166 FT Enoyl-CoA hydratase/isomerase signature." FT /db_xref="GOA:Q93JE8" FT /db_xref="InterPro:IPR001753" FT /db_xref="PDB:3G64" FT /db_xref="UniProtKB/TrEMBL:Q93JE8" FT /protein_id="CAC44593.1" FT /translation="MSPFTGSAAPTPEWRHLRVEITDGVATVTLARPDKLNALTFEAYA FT DLRDLLAELSRRRAVRALVLAGEGRGFCSGGDVDEIIGATLSMDTARLLDFNRMTGQVV FT RAVRECPFPVIAALHGVAAGAGAVLALAADFRVADPSTRFAFLFTRVGLSGGDMGAAYL FT LPRVVGLGHATRLLMLGDTVRAPEAERIGLISELTEEGRADEAARTLARRLADGPALAH FT AQTKALLTAELDMPLAAAVELDASTQALLMTGEDYAEFHAAFTEKRPPKWQGR" FT misc_feature 264627..265148 FT /note="Pfam match to entry PF00378 ECH, Enoyl-CoA FT hydratase/isomerase family, score 118.00, E-value 1.8e-31" FT misc_feature 264894..264956 FT /note="PS00166 Enoyl-CoA hydratase/isomerase signature" FT CDS 265384..267789 FT /transl_table=11 FT /gene="SCO5980" FT /gene_synonym="StBAC16H6.15" FT /product="putative bifunctional hydroxylase/oxidoreductase" FT /note="SCBAC16H6.15, possible bifunctional FT hydroxylase/oxidoreductase, len: 801aa: N-terminal region FT similar to hydroxylases eg. TR:Q9S3U8 (EMBL:AF172851) FT hydroxylase VioD from Chromobacterium violaceum (373 aa) FT fasta scores; opt: 549, Z-score: 591.4, 31.768% identity FT (33.430% ungapped) in 362 aa overlap and TR:Q9X7R5 FT (EMBL:AL049863) putative hydroxylase SC5H1.07c from FT Streptomyces coelicolor (421 aa) fasta scores; opt: 957, FT Z-score: 1027.4, 44.473% identity (47.527% ungapped) in 389 FT aa overlap. C-terminal region similar to oxidoreductases FT eg. TR:Q9R9V9 (EMBL:AF154061) xenobiotic reductase XenA FT from Pseudomonas putida (363 aa) fasta scores; opt: 895, FT Z-score: 962.0, 39.831% identity (40.517% ungapped) in 354 FT aa overlap and TR:Q9EX17 (EMBL:AL445503) putative FT oxidoreductase from Streptomyces coelicolor (359 aa) fasta FT scores; opt: 1008, Z-score: 1083.0, 46.667% identity FT (48.276% ungapped) in 360 aa overlap. Contains Pfam match FT to entry PF01360 Monooxygenase, Monooxygenase; Pfam match FT to entry PF00724 oxidored_FMN, NADH:flavin oxidoreductase / FT NADH oxidase family; Prosite match to PS00133 Zinc FT carboxypeptidases, zinc-binding region 2 signature and FT Prosite match to PS00383 Tyrosine specific protein FT phosphatases active site." FT /db_xref="GOA:Q93JE7" FT /db_xref="HSSP:1GWJ" FT /db_xref="InterPro:IPR003042" FT /db_xref="UniProtKB/TrEMBL:Q93JE7" FT /protein_id="CAC44594.1" FT /translation="MRSSQGSGADPGARGRVDQRLRRGARPAPTSPHSPAKTNHPLRAA FT IIGGGPGGLYTAALLKRLAPDREVTVYERNAPDDTFGFGVVLSDETLGGIEHADPTVYE FT ALKAHFVRWDDIDIVHRHTRHTSGGHRFAALGRRRLLEILHDRCRDLGVELRFRTEAPP FT PDRLARTHDLVVAADGVHSATREAYRDVFRPRLTPHRCRYIWLAADFAFDAFRFEIAET FT EHGVMQLHGYPFAPDASTVIVEMREEVWRAAGFDELDETESTARCAKIFADALGGRPLR FT SNKSAWTTFRTVVNERWSHGNIVLLGDAAHTAHFSIGSGTKLAVEDALALAACLAERPT FT LQEALTAYEEERRPVVASTQRAAKASLEWFEDLDRYLAQPPRQFAFNLLTRSRRVTHEN FT LRLRDAGFTESVEREFGCPPDTPPMFTPFRLRGLTLRNRVVVSPMDMYSATDGVPGDFH FT LVHLGARALGGAALVMTEMVCVSAEGRITPGCAGLYTGRQGEAWRRITDFVHDGAPGTA FT IGVQLGHSGRKGSTRLMWEGMDEPLPDGNWPLVAPSPLPYRPGGQVPRELSRAQLADVR FT EQFRAAAERAAGAGFDLLELHCAHGYLLSGFLSPLTNHRTDAYGGSPENRLRFPLEVFD FT AVREVWPDERPMTVRISATDWAEGGTSAEEAVEIARAFAAHGADAIDVSTGQVVSGERP FT EFGRSYQTPYADRIRHEAGVPVIAVGAISSWDDVNSLVLAGRTDLCALARPHLYDPHWT FT LHAAAEQGYDGPGARWPAPYRAGSRPPRTGRTDAPRPRLTLHGPGQDG" FT misc_feature 265891..266475 FT /note="Pfam match to entry PF01360 Monooxygenase, FT Monooxygenase, score 76.50, E-value 5.4e-19" FT misc_feature 266053..266085 FT /note="PS00133 Zinc carboxypeptidases, zinc-binding region FT 2 signature" FT misc_feature 266650..267672 FT /note="Pfam match to entry PF00724 oxidored_FMN, FT NADH:flavin oxidoreductase / NADH oxidase family, score FT 257.90, E-value 1.3e-73" FT misc_feature 267169..267207 FT /note="PS00383 Tyrosine specific protein phosphatases FT active site" FT CDS complement(267777..268688) FT /transl_table=11 FT /gene="SCO5981" FT /gene_synonym="StBAC16H6.16c" FT /product="hypothetical protein" FT /note="SCBAC16H6.16c, unknown, len: 303 aa: contains weak FT Pfam match to entry PF00685 Sulfotransfer, Sulfotransferase FT proteins" FT /db_xref="UniProtKB/TrEMBL:Q93JE6" FT /protein_id="CAC44595.1" FT /translation="MSLARNLNRALTVTTGLQVRRAPRAANGSPRGRQGGKSAAAQPAA FT RRAAPYRCPSAGELPTDRLLRRPVFIISSIRSGSTLLRMMMGAHPRLHAPHELHVGKVE FT VACTTWHSERAMGELGLLRGDLEHLLWDRVLHRELIRSGKDFVVEKTPANAYMYQRLKD FT CWPDARFVFLLRHPESIARSWHESDPVKRPHDTAVTDVLRYMTAVQEARSADADGFTVR FT YEDITGDPEREMRRLCAYLGVDYTPRMLNYGKKGNAELVRGLGDWRENIRTGTVQPGRE FT LPGKDEVPERLRPMCAAWGYPS" FT misc_feature complement(267795..268556) FT /note="Pfam match to entry PF00685 Sulfotransfer, FT Sulfotransferase proteins, score -78.50, E-value 0.1" FT CDS complement(268772..269617) FT /transl_table=11 FT /gene="SCO5982" FT /gene_synonym="StBAC16H6.17c" FT /product="putative regulator" FT /note="SCBAC16H6.17c, possible regulator, len: 281 aa: FT weakly similar to SW:P76086 (PAAX_ECOLI) phenylacetic acid FT degradation repressor protein from Escherichia coli (316 FT aa) fasta scores; opt: 266, Z-score: 305.3, 26.071% FT identity (28.077% ungapped) in 280 aa overlap." FT /db_xref="InterPro:IPR012906" FT /db_xref="UniProtKB/TrEMBL:Q93JE5" FT /protein_id="CAC44596.1" FT /translation="MINVSDLHLQPAPRSLIVTLYGAYGRCAPGPVPVAELIRLLAAVG FT VDAPSVRSSVSRLKRRGLLLPARTAAGAAGYELSAEARQLLDDGDRRVYATAPHGDEGW FT VLAVFSVPESERQKRHVLRSRLAGLGFGTAAPGVWIAPARLYAETRHTLGRLGLDSYVD FT FFRGEHLGFTATAEAVARWWDLAAIAKEHEAFLDRHERVLHDWERRADTPPEEAYRDYL FT LALDSWRHLPYTDPGLPARLLPEGWPGTRSAAVFRALHERLRDAGAQYAAMGPTPPPGQ FT " FT CDS complement(269619..271310) FT /transl_table=11 FT /gene="SCO5983" FT /gene_synonym="StBAC16H6.18c" FT /product="putative fatty acid-CoA ligase" FT /note="SCBAC16H6.18c, possible fatty acid-CoA ligase, len: FT 563 aa: similar to many e.g. TR:Q53005 (EMBL:U02033) FT 4-hydroxybenzoate-coenzyme A ligase rom Rhodopseudomonas FT palustris (539 aa) fasta scores; opt: 758, Z-score: 808.8, FT 33.747% identity (35.667% ungapped) in 483 aa overlap and FT TR:BAB48174 (EMBL:AP002995) probable acid-CoA ligase from FT Rhizobium loti (541 aa) fasta scores; opt: 1793, Z-score: FT 1909.7, 51.866% identity (53.565% ungapped) in 536 aa FT overlap. Contains Pfam match to entry PF00501 AMP-binding, FT AMP-binding enzyme and Prosite match to PS00455 Putative FT AMP-binding domain signature." FT /db_xref="GOA:Q93JE4" FT /db_xref="HSSP:1LCI" FT /db_xref="InterPro:IPR000873" FT /db_xref="UniProtKB/TrEMBL:Q93JE4" FT /protein_id="CAC44597.1" FT /translation="MADPRRADPHRSAHVDTFARDHLPPPEQWPELLFDLPELRYPERL FT NCAAELLTGPPGDRPVFRTASGETWTYQGLRDRVDRIAHVLTGDLGVVPGNRVLLRGPT FT GPWLAACWLAVLKAGAVAVTVLAQQRPHELRAICEIARVRHALCDVRAVDDLAKAEIAG FT LRITTYGGDAPDDLHSRTASDAVSPTPYRAVDTAADDVALIAFTSGTTGRPKGCMHFHR FT DVLAIADTFSAQVLKPRSDDLFAGSPPLGFTFGLGGLVVFPMRAGASALLLEQAGPKQL FT LPAVAEHRVSVLFTAPTAYRTMLDELDGYDVSSLRRCVSAGENLPAATWRAWHERTGLR FT VINGIGATELLHIFVSAADDDIRPGTTGVPVPGWHARVQDAHGAPVPDGEPGLLAVRGP FT VGCRYLADPRQREYVQDGWNVTGDTYVREPDGYFRYVARADDMIISAGYNIAGPEVEDA FT LLRHPDVVEAAVVGRPDRHRGQVVVAHAVLRDGAARDADALRAFLRAELAPYKCPREIL FT FPDALPRTATGKLQRYRLLDPAGPGPSPLPRDSSESPGRPGATPTT" FT misc_feature complement(269901..271058) FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 314.00, E-value 1.8e-90" FT misc_feature complement(270666..270701) FT /note="PS00455 Putative AMP-binding domain signature" FT CDS 271442..272617 FT /transl_table=11 FT /gene="SCO5984" FT /gene_synonym="StBAC16H6.19" FT /product="putative acyl-CoA dehydrogenase" FT /note="SCBAC16H6.19, possible acyl-CoA dehydrogenase, len: FT 391aa: similar to many eg. SW:P16219 (ACDS_HUMAN) acyl-CoA FT dehydrogenase from Homo sapiens (412 aa) fasta scores; opt: FT 676, Z-score: 741.3, 35.121% identity (37.006% ungapped) FT in 373 aa overlap and SW:P96879 (ACDP_MYCTU) probable FT acyl-CoA dehydrogenase from Mycobacterium tuberculosis (389 FT aa) fasta scores; opt: 735, Z-score: 805.9, 35.676% FT identity (37.394% ungapped) in 370 aa overlap. Contains FT Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA FT dehydrogenase, middle domain; Pfam match to entry PF00441 FT Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain and FT Prosite match to PS00072 Acyl-CoA dehydrogenases signature FT 1." FT /db_xref="GOA:Q93JE3" FT /db_xref="HSSP:1JQI" FT /db_xref="InterPro:IPR006092" FT /db_xref="UniProtKB/TrEMBL:Q93JE3" FT /protein_id="CAC44598.1" FT /translation="MTAFSLEPAQLTWCDELRALAAARLRPLAEQGEPGRVNRPLLAEL FT GSAGLLPRLFTSGALDLCLMRESLAHACTEAETALALQGLGAHPVHAHGTESQRARWLP FT RVSDGTAVAAFALSEPDAGSDAAALSLRAEPEAGPGAGASAWRLTGEKCWISNAPEADF FT YTVFARTTPGAGARGVTAFLVPADRPGLTGTPLDMLSPHPIGALTFDGVPVDADDVLGE FT PDRGFRVAMDTLNLFRPSVGAFAVGMAQAALDATLAHTTAREAFGGRLRDLQTVAHQVA FT EMALRTEAARLMVYAAATAYDAGDPDVPRRAAMAKLLATETAQYVVDHAVQLHGARALR FT RGHLLEHLYREVRAPRVYEGASEVQRGIVAKELYRTYQPSRTDATSKEAGA" FT misc_feature 271787..271825 FT /note="PS00072 Acyl-CoA dehydrogenases signature 1" FT misc_feature 271787..272017 FT /note="Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA FT dehydrogenase, middle domain, score 96.60, E-value 4e-26" FT misc_feature 272111..272563 FT /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA FT dehydrogenase, C-terminal domain, score 144.90, E-value FT 1.4e-39" FT CDS 272614..273012 FT /transl_table=11 FT /gene="SCO5985" FT /gene_synonym="StBAC16H6.20" FT /product="conserved hypothetical protein" FT /note="SCBAC16H6.20, conserved hypothetical protein, len: FT 132aa: similar to many eg. TR:BAB51882 (EMBL:AP003006) FT MLL5429 protein from Rhizobium loti (137 aa) fasta scores; FT opt: 271, Z-score: 331.4, 34.884% identity (35.156% FT ungapped) in 129 aa overlap. Contains Pfam match to entry FT PF01042 UPF0076, YjgF family." FT /db_xref="InterPro:IPR006175" FT /db_xref="UniProtKB/TrEMBL:Q93JE2" FT /protein_id="CAC44599.1" FT /translation="MTAERVNPPQLSPPTGFSHAVVATGTRVVFLAGQTALDTDGQVTG FT DTLPAQFEQALTNLLTALRAAGGTPADLARVTVYATDVAAYRTHAAELGRTWRELAGRD FT YPAMAVVEVVRLWDERALVELDGFAVLP" FT misc_feature 272638..273006 FT /note="Pfam match to entry PF01042 UPF0076, YjgF family, FT score 61.20, E-value 2.2e-14" FT CDS 273040..273867 FT /transl_table=11 FT /gene="SCO5986" FT /gene_synonym="StBAC16H6.21" FT /product="putative oxidoreductase" FT /note="SCBAC16H6.21, possible oxidoreductase, len: 275aa: FT similar to many eg. TR:O53622 (EMBL:AL021428) putative FT oxidoreductase from Mycobacterium tuberculosis (276 aa) FT fasta scores; opt: 521, Z-score: 601.4, 36.364% identity FT (38.314% ungapped) in 275 aa overlap and TR:Q53042 FT (EMBL:AF060871) haloalkane dehalogenase from Rhodococcus FT rhodochrous (293 aa) fasta scores; opt: 249, Z-score: FT 291.2, 28.417% identity (31.102% ungapped) in 278 aa FT overlap." FT /db_xref="InterPro:IPR000073" FT /db_xref="UniProtKB/TrEMBL:Q93JE1" FT /protein_id="CAC44600.1" FT /translation="MPDIELSAGTIEYEDTGGDGPVVVLLHGLVHDRTVWRKVLADLRT FT DHRVIAPTLPYGAHRRPMRRPPTPDLVNELIAEFLDRLDLTDVTLVENDCGRAQTVAAR FT HPERLARLALVACEAFDNYPPGLPGKLIGIACRAPGGVSLLVRTLGLGPLRRLPVGIGA FT LTKRPVPDEVVDGWLRPLRTDPAIRRDFRHYGTHVRREELLEAAQGLRRFDRPALVVWA FT TEDLMMPRAHGRRLAELLPRGRLVEVEDTRTLIPEDQPELLASLLREFVAEKD" FT CDS complement(273884..274093) FT /transl_table=11 FT /gene="SCO5987" FT /gene_synonym="StBAC16H6.21c" FT /product="conserved hypothetical protein" FT /note="SCBAC16H6.21c, conserved hypothetical protein, len: FT 69aa: similar to two others in Streptomyces coelicolor - FT TR:Q9AK87 (EMBL:AL583943) SC10A9.17 (chromosomal) (67 aa) FT fasta scores; opt: 276, Z-score: 372.9, 60.317% identity FT (63.333% ungapped) in 63 aa overlap and TR:Q9AD54 FT (EMBL:AL590463) SCP1.96 (plasmid) (79 aa) fasta scores; FT opt: 274, Z-score: 369.2, 59.322% identity (61.404% FT ungapped) in 59 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q93JE0" FT /protein_id="CAC44601.1" FT /translation="MCVHRPSCPASDSPEARVVTAHVVAAHPEQGWNLLCDGTVVFDDT FT GELLPDGRVVAPSRVPAGRLAMAA" FT CDS 274335..274778 FT /transl_table=11 FT /gene="SCO5988" FT /gene_synonym="StBAC16H6.23" FT /product="conserved hypothetical protein" FT /note="SCBAC16H6.23, conserved hypothetical protein, len: FT 147aa: weakly similar to others eg. TR:Q9RSG5 FT (EMBL:AE002049) hypothetical protein from Deinococcus FT radiodurans (255 aa) fasta scores; opt: 118, Z-score: FT 140.3, 28.873% identity (32.540% ungapped) in 142 aa FT overlap." FT /db_xref="InterPro:IPR010916" FT /db_xref="UniProtKB/TrEMBL:Q93JD9" FT /protein_id="CAC44602.1" FT /translation="MPVRSAALAAAAGAALLLPAAPAATAAPHDARLVAESVTVDPTGR FT IAADGSVTLSGTYRCTGGSGPVFVSSTVSQSDPSARFGVGGTRAVCDGLEHRWVNTGTP FT DTVVLEPGAAHVEATLMELRPMGIVPLPSFHARQGQDVILTAG" FT CDS complement(274897..275781) FT /transl_table=11 FT /gene="SCO5989" FT /gene_synonym="StBAC16H6.24c" FT /product="putative integral membrane protein" FT /note="SCBAC16H6.24c, possible integral membrane protein, FT len: 294aa: similar to TR:Q9K400 (EMBL:AL359949) putative FT integral membrane protein 2SCG61.15 from Streptomyces FT coelicolor (322 aa) fasta scores; opt: 900, Z-score: FT 931.3, 52.597% identity (59.124% ungapped) in 308 aa FT overlap. Contains possible membrane-spanning hydrophobic FT regions" FT /db_xref="UniProtKB/TrEMBL:Q93JD8" FT /protein_id="CAC44603.1" FT /translation="MYEEHYGEHTHPRMPYGEGPFRTTGTGRHRAPEAAFQETLVPPEP FT GWDPAEELAFLLQDAMEQQPGAPSATDTSALAPAPGTPLSNLQEITAELPPLRESPTSH FT RRVRRGRKVSRLRAASLFVAALAAVIAASVSLFGGMVAYEPLRLAAVTRTRGSVVSWWP FT LLVYGPWLVASLAVLRAALHQRRAVHSWAVVLLFSAIAMLLCIAEAPRTISDGAAAALP FT GLASLVCFQQVVRQITLTRPPRRAVPRHRQRAAVTPGDDPSGSAAADPVSLPQQRQNVV FT RPPRPGAGPGKRT" FT CDS complement(275792..276028) FT /transl_table=11 FT /gene="SCO5990" FT /gene_synonym="StBAC16H6.25c" FT /product="hypothetical protein" FT /note="SCBAC16H6.25c, unknown, len: 78 aa: no significant FT database matches." FT /db_xref="UniProtKB/TrEMBL:Q93JD7" FT /protein_id="CAC44604.1" FT /translation="MTEERGEFTALGPYTYRPGRSHCPSPSDGTLTRGGHPVPLRVTEP FT VLQRFLDVMTELETGLAERWGRTQGSLTYTRAE" FT CDS 276263..276649 FT /transl_table=11 FT /gene="SCO5991" FT /gene_synonym="StBAC16H6.26" FT /product="putative secreted protein" FT /note="SCBAC16H6.26, possible secreted protein, len: 128aa: FT no significant database matches. Contains a possible FT N-terminal signal sequence." FT /db_xref="UniProtKB/TrEMBL:Q93JD6" FT /protein_id="CAC44605.1" FT /translation="MKRAAPGRAPAHVRSVLALLVAVVGLLCVFAHAESGARGTPAPTA FT ERVHTAAAAPAAAEPSDGAAAPCGKKAIGDSSVQRAENPPPSAAFPRATSPHTDPAPLV FT PQHVGVFAGGPDPPSPTLHSVLRM" FT CDS 276701..277195 FT /transl_table=11 FT /gene="SCO5992" FT /gene_synonym="StBAC16H6.27" FT /product="putative integral membrane protein" FT /note="SCBAC16H6.27, possible integral membrane protein, FT len: 164aa: no significant database matches. Contains FT possible membrane-spanning hydrophobic regions." FT /db_xref="UniProtKB/TrEMBL:Q93JD5" FT /protein_id="CAC44606.1" FT /translation="MSSSPRSWRRAGTALRGWRSRQWTVTGAGALATAVLVGAPTDVVP FT NPLFGRSVPVQWWNYPALAVTAVLAGIVLTTYVRRPSSAPEPHAADGGRLGAIGGVLSF FT FAVGCPVCNKLVLVLLGASGALSYWAPLQPLLAVLSAGLLAEAALRRLSSETACPVTPS FT A" FT CDS 277262..278074 FT /transl_table=11 FT /gene="SCO5993" FT /gene_synonym="StBAC16H6.28" FT /product="putative membrane protein" FT /note="SCBAC16H6.28, possible membrane protein, len: 270aa: FT weakly similar to TR:BAB53967 (EMBL:AP003012) MLR7525 FT protein from Rhizobium loti (250 aa) fasta scores; opt: FT 340, Z-score: 379.4, 28.400% identity (30.603% ungapped) FT in 250 aa overlap. Contains a possible membrane-spanning FT hydrophobic region" FT /db_xref=" |