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EBI DbfetchID AL939124; SV 1; linear; genomic DNA; STD; PRO; 308050 BP. XX AC AL939124; AL023797; AL031031; AL031035; AL031124; AL031225; AL031231; AC AL031260; AL034447; AL035559; AL035569; AL355913; XX DT 25-OCT-2002 (Rel. 73, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 4) XX DE Streptomyces coelicolor A3(2) complete genome; segment 21/29 XX KW . XX OS Streptomyces coelicolor OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Streptomycineae; Streptomycetaceae; Streptomyces. XX RN [1] RP 1-308050 RA Bentley S.D.; RT ; RL Submitted (09-MAY-2002) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Streptomyces sequencing team, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL sdb@sanger.ac.uk XX RN [2] RX DOI; 10.1038/417141a RX PUBMED; 12000953. RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L., RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H., RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E., RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D., RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.; RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor RT A3(2)"; RL Nature 417(6885):141-147(2002). XX DR EMBL-CON; AL645882. DR RFAM; RF01118; PK-G12rRNA. DR SILVA-LSU; AL939124. DR SILVA-SSU; AL939124. XX FH Key Location/Qualifiers FH FT source 1..308050 FT /organism="Streptomyces coelicolor" FT /strain="A3(2)" FT /mol_type="genomic DNA" FT /db_xref="taxon:1902" FT CDS 250..2490 FT /transl_table=11 FT /gene="SCO5495" FT /gene_synonym="SC8D9.07" FT /product="putative phosphodiesterase" FT /note="SC8D9.07, possible membrane associated FT phosphodiesterase, len: 746 aa; similar to many eg. FT TR:O87376 (EMBL:AF052518) c-di-GMP phosphodiesterase A from FT Acetobacter xylinus cdg2 operon (752 aa) fasta scores; opt: FT 959, z-score: 1059.2, E(): 0, (31.7% identity in 603 aa FT overlap). Appears to have two distinct regions with the FT first 300aa containing several potential membrane spanning FT hydrophobic regions and the remainder of the protein FT showing similarity to the phosphodiesterase mentioned FT above. Also similar to a nearby gene on the same cosmid FT (SC8D9.22) fasta scores; opt: 736, z-score: 625.6, E(): FT 5.3e-30, (32.6% identity in 729 aa overlap). Contains TTA FT Leu codon, possible target for bldA regulation. Also FT contains Pfam match to entry PF00990 DUF9, Domain of FT unknown function, score 166.70, E-value 3.9e-46 and Pfam FT match to entry PF00563 DUF2, Domain of unknown function 2, FT score 291.30, E-value 1.2e-83. Contains possible FT hydrophobic membrane spanning regions" FT /db_xref="InterPro:IPR001633" FT /db_xref="UniProtKB/TrEMBL:Q9Z584" FT /protein_id="CAB37571.1" FT /translation="MEPTESAAAGSRLRLRRMADAWHVSRWLGQRDGGVPSSMTGTRVP FT QAVGRPHGHPQGHPHGLVDPDGERHLSWPALPAAVVATAAFVLGAGFYRAFSDGHALFP FT AGTVGWSLAVLSGIVVGHLVMLGRSRWWGGTGSGAALTLAVLLLYGWIPAGMVSLTVVV FT LVGIARRGRWRQGVLHGAVDILGIAAGAVVLGVCGSVPSVERPWDPETWGVYAAPKVVL FT VAVAYLAVTRALLWYIQTPRPGLPTAARTALVRHGLVAVALLGIAPLICVVAVAKPLLL FT PLFAIPLIALDSTLWIARARAEEQLRDPLTGLPNRQWLLERTWTALDDAERIGARAALM FT LIDLDRFRSVNDTLGHLAGDRLLLQTADRLRQALPRGAEAARLGGDEFAVLLPVADSTT FT SATRIARSLVGALSSPMDLDGLTLVLEASAGVAVFPDHALDAEGLLRRADVAMYQAKRD FT RTGVEVYESKRDSNTPDRLGLLGDLRRALDAHEVQLHYQPKVRFDGQVAGLEALVRWVH FT PERGKVPPDEFIAIAESSGLMPHLTEYVLETALGQVARWRAQGLFVPVAVNVSPRDVHT FT PGFAGSVAARLARHGVPAGALQLEITEHVLLEDPQRAADTLNALTGHGVKMSLDDFGTG FT YSSLVHLRRLPVSELKIDRSFVARLAIDNEDAEIVRCTVDLAHSLGLLVVAEGVEDDET FT WERLRDLGCDAVQGWLVAAAMPPEETTAWLLARGSRGWVRAAAALPAAASDE" FT misc_feature 1141..1635 FT /note="Pfam match to entry PF00990 DUF9, Domain of unknown FT function, score 166.70, E-value 3.9e-46" FT misc_feature 1420..1422 FT /note="TTA Leu codon, possible target for bldA regulation" FT misc_feature 1672..2406 FT /note="Pfam match to entry PF00563 DUF2, Domain of unknown FT function 2, score 291.30, E-value 1.2e-83" FT CDS 2774..3145 FT /transl_table=11 FT /gene="SCO5496" FT /gene_synonym="SC8D9.08" FT /product="putative small membrane hydrophobic protein" FT /note="SC8D9.08, small hydrophobic membrane protein, len: FT 123 aa; no significant database similarities. Contains FT possible hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9Z583" FT /protein_id="CAB37572.1" FT /translation="MTVTAYTLAVVLNLFCLFLGYRFLFQPASAATGYGVPADAGGDAA FT AYLTVKGVRDGTLGVVGLALLAFAGARPEAWFMLCVALVPLADTLIVLRHGGTKAVAFG FT IHFATAIVVLISAGLLFAV" FT CDS 3177..3671 FT /transl_table=11 FT /gene="SCO5497" FT /gene_synonym="SC8D9.09" FT /product="conserved hypothetical protein" FT /note="SC8D9.09, unknown, len: 164aa; similar to many of FT undefined function eg. TR:O06336 (EMBL:Z95390) hypothetical FT protein from Mycobacterium tuberculosis (177 aa) fasta FT scores; opt: 171, z-score: 213.4, E(): 0.00014, (34.9% FT identity in 109 aa overlap)." FT /db_xref="InterPro:IPR014710" FT /db_xref="UniProtKB/TrEMBL:Q9Z582" FT /protein_id="CAB37573.1" FT /translation="MSLFVPKFDESVVVREAEAEVVGRAPTTVRLLADSSSTGGALSTQ FT RVTLTAGADGAKPHWHDNSAEMFFLLDGAADVLSGDEVLTAGPGDLIVVPPGKPHAFAA FT VPGADADLLIVLAPGVERFEYFRHLQRIALGEATPESLLEVQELYDNHFLSSAAWDARR FT G" FT CDS 3816..4112 FT /transl_table=11 FT /gene="SCO5498" FT /gene_synonym="SC8D9.10" FT /gene_synonym="gatC" FT /product="probable Glu-tRNAGln amidotransferase subunit C" FT /note="SC8D9.10, probable Glu-tRNA-Gln amidotransferase FT subunit C, gatC, len: 98aa; similar to many eg. TR:O06492 FT (EMBL:AF008553) Glu-tRNAGln amidotransferase subunit C, FT gatC, from Bacillus subtilis (101 aa) fasta scores; opt: FT 232. z-score: 294.8, E(): 4.1e-09, (42.1% identity in 95 aa FT overlap)." FT /db_xref="GOA:Q9Z581" FT /db_xref="InterPro:IPR003837" FT /db_xref="UniProtKB/Swiss-Prot:Q9Z581" FT /protein_id="CAB37574.1" FT /translation="MPGITREEVAHLARLARLELKPEELEHFAGQLDDIIGAVARVSEV FT ADQDVPPTSHPLPLTNVMRPDEVRPSLTPEQALSGAPAQEQQRFKVPQILGEE" FT CDS 4116..5609 FT /transl_table=11 FT /gene="SCO5499" FT /gene_synonym="SC8D9.11" FT /gene_synonym="gatA" FT /product="probable Glu-tRNA Gln amidotransferase subunit" FT /note="SC8D9.11, probable Glu-tRNA-Gln amidotransferase FT subunit A, gatA, len: 497aa; similar to many eg. TR:O06491 FT (EMBL:AF008553) Glu-tRNAGln amidotransferase subunit A, FT gatA, from Bacillus subtilis (486 aa) fasta scores; opt: FT 1443, z-score: 1512.5, E(): 0, (52.0% identity in 465 aa FT overlap)." FT /db_xref="GOA:Q9Z580" FT /db_xref="HSSP:1M21" FT /db_xref="InterPro:IPR004412" FT /db_xref="UniProtKB/Swiss-Prot:Q9Z580" FT /protein_id="CAB37575.1" FT /translation="MSDIIKLTAAEIAAKIASGELTAVQVTEAHLARIEAVDEKVHAFL FT HVDREGALAQARAVDEKRERGEKLGPLAGVPLALKDIFTTEGIPTTVGSKILEGWIPPY FT DATVTKRLKAADVVILGKTNMDEFAMGSSTENSAYGPTGNPWDLTKIPGGSGGGSSAAL FT AAFQAPLAIGTDTGGSIRQPASVTGTVGVKPTYGGVSRYGMVAFSSSLDQGGPCARTVL FT DAALLHEVIAGHDPMDSTSIDAPVPAVVEAARNGSVDGMRVGVVKQFRGEGYQAGVVQR FT FDESVELLKSLGAEIVELDCPSFDLALSAYYLIAPSECSSNLARFDGLRYGARVGDDGT FT HSAEEVTSLTREAGFGPEVKRRIMLGTYALSSGYYDAYYGSAQKVRTLIKQEFERAFEQ FT VDVIVSPTTPTTAFAIGERADDPMAMYLADLCTIPTNLAGNAAMSLPCGLAPEDNLPVG FT LQIIAPAMKDDRLYKVGAAVEAAFVEKWGHPLIEEAPSL" FT CDS 5606..5845 FT /transl_table=11 FT /gene="SCO5500" FT /gene_synonym="SC8D9.12" FT /product="putative membrane protein" FT /note="SC8D9.12, putative membrane protein, len: 79 aa. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9Z579" FT /protein_id="CAB37576.1" FT /translation="MSALTKAKGFKKSKSGLYVSMATSAFGAVGVYKQIKKARGESDTL FT RLLDAVVTGAAVVTNLAILYRELKRLGDDDVLLG" FT CDS 5861..7375 FT /transl_table=11 FT /gene="SCO5501" FT /gene_synonym="SC8D9.13" FT /gene_synonym="gatB" FT /product="probable Glu-tRNAGln amidotransferase subunit B" FT /note="SC8D9.13, probable Glu-tRNA-Gln amidotransferase FT subunit B, gatB, len: 504aa; similar to many eg. TR:O30509 FT (EMBL:AF008553) Glu-tRNA-Gln amidotransferase subunit B, FT gatB, from Bacillus subtilis (476 aa) fasta scores; opt: FT 886, z-score: 983.5, E(): 0, (42.9% identity in 485 aa FT overlap)." FT /db_xref="GOA:Q9Z578" FT /db_xref="InterPro:IPR017958" FT /db_xref="UniProtKB/Swiss-Prot:Q9Z578" FT /protein_id="CAB37577.1" FT /translation="MTTTTDLVSYEDALASYDPVMGLEVHVELGTKTKMFCGCSTALGA FT DPNTQTCPVCLGMPGALPAVNATGVESAIKIGLALNCEIAEWCRFARKNYFYPDMPKNF FT QTSQYDEPIAFDGYLDVQLEDGETFRVQIERAHMEEDTGKSLHVGGATGRIHGASHSLL FT DYNRAGIPLIEIVTKPIEGAGERAPEVARAYVRELRELIRALGVSEARMEMGQMRCDVN FT LSLRPHGREKFGTRSETKNVNSLRSVERAARFEIQRHAAVLNDGGTIIQETRHFHEDTG FT STTSGRVKEEAEDYRYFPEPDLVPVAPSRQWVEEIRSGLPELPLVRRNRLREEWGISGN FT DMQSILNAGALDPIVATIDAGADAASARKWWMGELARSANESGKALDELAITPVQVARV FT AELVTKGELNDKLARQVILGVLAGEGTPDEVVDKRGLKVVSDEGALTTAVDEAIAGNPG FT VADKIRGGKVAAAGALVGAVMKATRGQADAARVKELILEKLGVAEG" FT CDS 7617..9863 FT /transl_table=11 FT /gene="SCO5502" FT /gene_synonym="SC8D9.14" FT /product="putative integral membrane export protein" FT /note="SC8D9.14, possible integral membrane export protein, FT len: 748aa; similar to many eg. TR:Q53902 (EMBL:M64683) an FT intergral membrane protein involved in the export of FT actinorhodin from Streptomyces coelicolor (711 aa) fasta FT scores; opt: 353, z-score: 385.2, E(): 3.8e-14, (28.2% FT identity in 731 aa overlap)." FT /db_xref="GOA:Q9Z577" FT /db_xref="InterPro:IPR000731" FT /db_xref="UniProtKB/TrEMBL:Q9Z577" FT /protein_id="CAB37578.1" FT /translation="MAALARWCVQRRLVTVLLWLLALGGVATAATVAGSAYSNDYGIPG FT TGSDRASRLLESRFPDLGGDSDTIVWHTTSGTVRAADVEQAMTRTLDRIADLPGVAAVS FT NPYHDADSPLISENADTAYATVTFEDASQDLDPGQARAVVDTAEAAETGGLRIELGGGA FT IALTESGGSHLAEAVGVAVAAVVLFLAFGSVAAALLPIATALVSVGTAYAGITLLGHAM FT TVADFAPMLGTLIGLGVGIDYALFIVTRHRRGLKRGLSVADAAADAVATTGRAVVFAGA FT TVCIALLGMLILRLSFLNGVAVAASLTVLLTVAASVTLLPALLSYIGPRALSRRERRRL FT AEHGPEPEVPTGFAARWSAFVERRPKLLGALALVVITVVALPTLGLRLGTSDQGNDPQG FT TTTRQAYDLLADGFGPGVNGPLTLVTEVRGAEDRLALDNLDATLRTTEGVSSVTPVMYN FT SGGDAAYLTVVPESAPQSEDTSDLVERLRSEVLPRAEAGTALDVHVGGVTAGYDDFADV FT IVGKLPLFVGVVIGLGCLLLLLAFRSVGIPLKAAAMNVAAVAAAFGVVVAIFQWGWGSE FT LLGLGSAGPIEPFLPVIMVSVLFGLSMDYQVFLVSRMYEEWLETGDNRRAVRVGLAETG FT RVINSAAVIMISVFLAFVLSGDRVIAMFGIALAAAVALDAFVLRTLLVPALMHLLGRAN FT WWLPRRLDALLPRISIEPPECRAAHERLAAATDAEVADVLAEEERQRDVRDTTG" FT CDS 9841..10425 FT /transl_table=11 FT /gene="SCO5503" FT /gene_synonym="SC8D9.15" FT /product="putative acetyltransferase" FT /note="SC8D9.15, possible acetyltransferase, len: 194aa; FT similar to many eg. TR:P96579 (EMBL:AB001488) probable FT acetyltransferase from Bacillus subtilis (183 aa) fasta FT scores; opt: 250, z-score: 327.1, E(): 6.5e-11, (27.9% FT identity in 172 aa overlap)" FT /db_xref="GOA:Q9Z576" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9Z576" FT /protein_id="CAB37579.1" FT /translation="MYAIPLGDDGAELRPLETWHAEEFLAHLDRGRDFITEHIPFGAKA FT TDVDSAREVLQAYADRHAADSGFLHGLWLDGTLVGGLLYRVFDAATGVCEIGCWLEPAG FT TGRGLVTRGARVLIDWAFDERGMHRVEWYASTANTPSANAARRLGMMREGVLRESFPHR FT GTRQDMEVWAVLAPEWRAAREARARAAQRDH" FT CDS 10461..11087 FT /transl_table=11 FT /gene="SCO5504" FT /gene_synonym="SC8D9.16" FT /product="putative integral membrane protein" FT /note="SC8D9.16, possible integral membrane protein, len: FT 208aa; alanine-rich, contains possible membrane spanning FT regions." FT /db_xref="UniProtKB/TrEMBL:Q9Z575" FT /protein_id="CAB37580.1" FT /translation="MGTKTVDETGVKTDEHKTDEAADAAEATEAPESIDVTKAAEAPEA FT AGTDTPEDADASMDEDTDEGPDGTGTEGTGAAPTGVGQGAGAVVSAGLGIVSLTGSWVG FT TVASARESLMGQLQTSSSSDVGTLIEKGYGNAWQATAMWGGIFALVALIVGVVVLARPA FT FGAPGRPQAPWIKSVAWAGVALGVIGLLLAVLKYTDVLLGLPATG" FT CDS 11283..11468 FT /transl_table=11 FT /gene="SCO5505" FT /gene_synonym="SC8D9.17" FT /product="hypothetical protein" FT /note="SC8D9.17, unknown, len: 61 aa" FT /db_xref="UniProtKB/TrEMBL:Q9Z574" FT /protein_id="CAB37581.1" FT /translation="MYEYEFQQYRSAELIRRADEARLAREVVRARRAARRQARHGGAVA FT ESHTPRRRGHRFARTA" FT CDS 11465..14740 FT /transl_table=11 FT /gene="SCO5506" FT /gene_synonym="SC8D9.18" FT /product="putative regulatory protein" FT /note="SC8D9.18, possible regulatory protein, len: 1091 aa; FT limited similarity to many proteins associated with FT regulatory functions e.g. C-terminal similarity with FT C-terminal of TR:O86603 (EMBL:AL031155) putative FT transcriptional regulator from Streptomyces coelicolor (892 FT aa) fasta scores; opt: 245, z-score: 254.6, E(): 7.1e-07, FT (30.6% identity in 451 aa overlap). Contains PS00017 FT ATP/GTP-binding site motif A (P-loop) and a probable FT helix-turn-helix at 1036-1057aa (+3.98 SD). Also contains FT Pfam match to entry PF00196 GerE, Bacterial regulatory FT proteins, luxR family, score 82.70, E-value 7.8e-21." FT /db_xref="GOA:Q9Z573" FT /db_xref="HSSP:1FSE" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9Z573" FT /protein_id="CAB37582.1" FT /translation="MNGGAGEGGRTASLPAVVPAAVAGVVHLPKTGDPLSYPRAMLASV FT ETRSVSPVFVGRTGELDTLNDALARATGSDTAGATAAGATATRASATGGEPQALLLGGE FT AGVGKTRLVEEFAAAADRRGAVVALGGCVEIGADGLPFAPFSTALRALRRHLPEELAAA FT AAGQEEELARLLPELAEGTPVTGGGRHDEESMARLFELTARLLERVAARHTVVLVLEDL FT HWADASTRHLIAYLLRTLRTGRLVVLATYRSDDIHRRHPLRPLLAELDRLRTVRRLELG FT RFTRDEVGRQIAGILAHEPDQLQVDEIFERSDGNAFFVEELAVAARVGSCTGLTDSLRD FT LLLVRVEALPESAQRVARIVAEGGSTVEYRLLAAVARLAEDDLIEALRSAVNANILLPA FT PDGDGYRFRHSLVREAVGDDLLPGERSRLNRRYAEALDADPTLVPAAERVMRLASYWYH FT AHAPAKALPAVLDASVEARRRHAYSEQLRLLERAMELWDSAPDDVRATLRPVDCTEVYP FT PRACDPATTPLRYLDLMAEAAVAGRLCGERERAMKITKRALRLLEDEQDTGTGAGASGR FT DPQRAAWFWTQRSLLVQAQGRGDGWRELGIAQELVRGLPPSQVHAEVLAMSANWSMLHS FT PGPDAMTAAERAVEYARMVGAEEIELNARLTLGGLMVDAGQIDAGLAEMFQVRDLVVAQ FT DRSAVVARSHVNLPSSLEGVGRSRDALGILREGIDLTRRRGLLESEAWVWGNLAESLIS FT LGRWDEALEAADRAGAPGRSPAPRGGAALKRAVVALARGERAEAAGLLAEARAAYGTHD FT PMPQHRLPLAALAVGVAAAEGRLPDARAELVRVLDAGFPPGTQRFGWPLLLSAAAAEAD FT ARALPAAEEGRAGLLDRLAEAAKHLTTGAPVWVAHERWVRAELHRARGRDTPRLWSEAV FT TAFECLERPYDLARVRYRLADALLAAGGDDERARATELLRLARTVADHLGARPLSDAVA FT VLGRRARLTLGRAAGPVPASGPADPADALGLTGRERDVLRLVSDGRTNRQIAEELFISP FT KTASVHVSNILAKLGVSGRGEAAAVAHRLALFPAERLTSPSPE" FT misc_feature 11771..11794 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 14513..14710 FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 82.70, E-value FT 7.8e-21" FT CDS 14778..14987 FT /transl_table=11 FT /gene="SCO5507" FT /gene_synonym="SC8D9.19" FT /product="hypothetical protein" FT /note="SC8D9.19, unknown, len: 69 aa" FT /db_xref="UniProtKB/TrEMBL:Q9Z572" FT /protein_id="CAB37583.1" FT /translation="MFNAFEELFSPGRKHTNDEQNRLELTREDVGDGDPGHGPIDLTSG FT KVVVHRPRADEEAEEPGTPSPEDE" FT CDS complement(14996..16339) FT /transl_table=11 FT /gene="SCO5508" FT /gene_synonym="SC8D9.20c" FT /product="putative oxidoreductase" FT /note="SC8D9.20c, possible oxidoreductase, len: 447aa; FT similar to many of undefined function and SW:DHGB_ACICA FT glucose dehydrogenase-B from Acinetobacter calcoaceticus FT (478 aa) fasta scores; opt: 247, z-score: 253.8, E(): FT 7.9e-07, (27.4% identity in 369 aa overlap)." FT /db_xref="GOA:Q9Z571" FT /db_xref="InterPro:IPR012938" FT /db_xref="PDB:3DAS" FT /db_xref="UniProtKB/TrEMBL:Q9Z571" FT /protein_id="CAB37584.1" FT /translation="MRPAAPGRPESGAGVRGSRLAVRGSRFAARGSGFGDREPGERLRC FT MTGRTRRVEGTKIVQRRAVPAVLTAALLLTAGCSSGSSDGADPSKTDRGASPTSTAAQS FT SPAGSPTEQAPPAKGSVKVLRTVATGLNSPWGLAPLPGGDLLVSSRDEATITRVDAKTG FT RKTELGEVPGVSPSGEGGLLGIALSPDYASDHMVYAYFTSASDNRIVRMLYDEKKPSGE FT QLGAPDTVFRGIPKGVIHNGGRIAFGPDKMLYAGTGESGDTGLSQDRKSLGGKILRMTP FT DGEPAPGNPFPGSPVYSYGHRNVQGLAWDDKQRLFASEFGQDTWDELNAIKPGDNYGWP FT EAEGKGGGSGFHDPVAQWSTDEASPSGIAYAEGSVWMAGLRGERLWRIPLKGTAAAADP FT QAFLEGEYGRLRTVAPAGGDKLWLVTSNTDGRGDAKGGDDRILELEVE" FT CDS complement(16336..17268) FT /transl_table=11 FT /gene="SCO5509" FT /gene_synonym="SC8D9.21c" FT /product="putative oxidoreductase" FT /note="SC8D9.21c, probable oxidoreductase, len: 447aa; FT similar to many both prokaryotic and eukaryotic egs. FT SW:A115_TOBAC auxin induced protein (probable FT oxidoreductase) from Nicotiana tabacum (common tobacco) FT (307 aa) fasta scores; opt: 391, z-score: 456.6, E(): FT 4e-18, (36.7% identity in 289 aa overlap) and TR:O07152 FT (EMBL:Z96801) putative oxidoreductase from Mycobacterium FT leprae (306 aa) fasta scores; opt: 336, z-score: 393.5, FT E(): 1.3e-14, (30.8% identity in 295 aa overlap). Contains FT Pfam match to entry PF00248 aldo_ket_red, Aldo/keto FT reductase family, score 33.70, E-value 4.6e-09." FT /db_xref="GOA:Q9Z570" FT /db_xref="InterPro:IPR001395" FT /db_xref="UniProtKB/TrEMBL:Q9Z570" FT /protein_id="CAB37585.1" FT /translation="MNWAYSASRQRGDESLRAVHRALDLGVSLLDTADMYGPFTNELLL FT GRVLRERRSEAFVSTKVGLLVGEQHIVANGRPGYVRRACDASLRRLQTDVIDLYQLHRA FT DPEIPVEETWGAMAELVRAGKVRALGLCAVGARSARRPGARLHDATIRQLERVQQVFPV FT SAVEAELSVWSPEALRTLLPWCVSRGVGFLAAMPLGNGYLTGTLTPGQGFEPEDLRARH FT PRFTAEMMAANQPIVAALRRIAARHGDGVTAAQVALAWVLAQGRHVVPVPGTKQERWVT FT QNAGAARLRLTERDLAEVRVLPPGQGSWE" FT misc_feature complement(16873..17031) FT /note="Pfam match to entry PF00248 aldo_ket_red, Aldo/keto FT reductase family, score 33.70, E-value 4.6e-09" FT CDS 17409..18350 FT /transl_table=11 FT /gene="SCO5510" FT /gene_synonym="SC8D9.22" FT /product="putative dehydrogenase" FT /note="SC8D9.22, probable dehydrogenase, len: 313aa; FT similar to many both eukaryotic and prokaryotic egs. FT SW:FDH_SOLTU NAD-dependent formate dehydrogenase from the FT mitochondria of Solanum tuberosum (potato) (379 aa) fasta FT scores; opt: 372, z-score: 413.2, E(): 1e-15, (29.9% FT identity in 278 aa overlap) and SW:SERA_BACSU FT D-3-phosphoglycerate dehydrogenase from Bacillus subtilis FT (525 aa) fasta scores; opt: 348, z-score: 384.9, E(): FT 3.9e-14, (32.4% identity in 256 aa overlap). Contains FT PS00671 D-isomer specific 2-hydroxyacid dehydrogenases FT signature 3 and Pfam match to entry PF00389 2-Hacid_DH, FT D-isomer specific 2-hydroxyacid dehydrogenases, score FT 147.40, E-value 5.1e-60." FT /db_xref="GOA:Q9Z569" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9Z569" FT /protein_id="CAB37586.1" FT /translation="MTADVWLPIPPDEIEGLPEGPAYRHWDGEEAFPADPADCAFYVVP FT YMKPSTVGVRPLPGMRSVQVVQTLSAGIDHVEPGLGHLPAGVRLCNARGVHEASTAELT FT LALILASLRGIPDFVRAQDRGEWLGGFRPALADRTVLIVGYGSIGAAIEDRLVPFEVAP FT VVRVARSARTTERGPVHPLTELPRLLPQADVVILSTPLTEATRGLAGAEFLARMKDGAL FT LVNVARGPVVDTKALLAELESGRLTAALDVTDPEPLPPGHPLWHAPGIVVSPHAGGPTS FT AFLPRAERLLVDQLTRFVNREPLRNVILTTGS" FT misc_feature 17703..18233 FT /note="Pfam match to entry PF00389 2-Hacid_DH, D-isomer FT specific 2-hydroxyacid dehydrogenases, score 147.40, FT E-value 5.1e-60" FT misc_feature 18057..18107 FT /note="PS00671 D-isomer specific 2-hydroxyacid FT dehydrogenases signature 3." FT CDS 18549..21875 FT /transl_table=11 FT /gene="SCO5511" FT /gene_synonym="SC8D9.23" FT /product="putative membrane associated phophodiesterase" FT /note="SC8D9.23, possible large membrane associated FT phophodiesterase , len: 1108aa; the first 400aa of this FT protein appear to contain several potential membrane FT spanning regions. The remainder shows similarity to several FT eg. TR:O87378 (EMBL:AF052519) C-DI-GMP phophodiesterase A FT from Acetobacter xylinum (740 aa) fasta scores; opt: 683, FT z-score: 565.4, E(): 3.4e-24, (27.3% identity in 645 aa FT overlap). Also similar to a nearby gene on the same cosmid FT (SC8D9.07) fasta scores; opt: 736, z-score: 499.5, E(): FT 5.6e-23, (32.4% identity in 728 aa overlap). Contains Pfam FT match to entries PF00989 PAS, PAS domain, score 34.90, FT E-value 1.8e-06, PF00990 DUF9, Domain of unknown function, FT score 167.40, E-value 2.3e-46 and PF00563 DUF2, Domain of FT unknown function 2, score 152.30, E-value 8.3e-42." FT /db_xref="GOA:Q9Z568" FT /db_xref="InterPro:IPR013767" FT /db_xref="UniProtKB/TrEMBL:Q9Z568" FT /protein_id="CAB37587.1" FT /translation="MDRRSDAAEPPPATLAHGHDHDRAPTGSARPPRRPARSALPPPAP FT TGRPQQAGPAGPPVRAGRGSGADPEAPVSPPPAPTLDGALRGQAAPGPLLPRPSAAAGG FT PPLVRQLVLALVCAAYAVGAALGWGSQYVAKIMGDFGLSAAAAAAAVSCFLYARGRRVR FT FRPAWLLFALSSAMASLGNLVWGWYEVVLRVPVPNPSYADLFFLCFAPPAIVGLLVLAK FT RPVTKAGWICLGLDAWLIGGSLLTLAWSLALAQAAKAEGGSSVAHAALSVAYPLLDIAL FT VSMVLALHFRRSPVCRSAVNTAIGALALTVVCDALFTSPLLHNSYRSGQLLDAGWFAGS FT LLLAYAPWAASRRGRATPDETGTGGHTRVVREHVPGQRGSGHQPPPPSAPSAPPPSAPT FT ALPGPGQGGERGRYPAARPIAGSLAALTPYLAAAVCTLGILYNVLNGRSVDRVVLLTGG FT TVVLALVVRQGIMLLDNIVLTQELAQKENHFRSLVQGSSDVIMIAAPNGILRYVSPAAA FT GVYGRPAEELVGTELAGLIHPEDLGCVVHEVRRFLAANPVEEPTTRIECRFRSGGGGGW FT LNVESTVNRHHGGLIFNSRDVTERVRLQAQLQHNAEHDPLTDLPNRALFTRRVQQALSG FT RRASDRGAALRGTAVLFIDLDGFKGVNDTIGHQAGDELLVQAARRLHEAVRKGDTASRL FT GGDEFAALIVGDGARDRAAREGHIRELADRLRLTLSQPYLIDGNEVRVNASIGVAFAEP FT GLGAGELLRNADLAMYRAKAGGKGRVELYRPQMQQDVVRKAELATRLRAALHDGEFALL FT HQPVVSLTDGRITSVCAQARWRSSQGVLFTPAEFLRVTEEGDRTAELDRWVLREAVEQA FT AERAAAGLSVSVAIRIGARRLLDRSMPLGSVEALLTRHGLPPGSLVIELSDIDPRVGLD FT ELDRRLNALRRVGVRIALDGFGSGYAAITALRRLPVDVLKLDRGLVEGVVESARLHKIT FT SGLLRIATDLGLKSVADGVDLPEQIVALRAMGCTHGQGMAFSGALDEYRLRRALAAGHY FT PVPHGPAEPAFAGGGAGVYAKGVGGPGPGQVTGGVPSGLPAVLSGGTALRSHNETPVPP FT T" FT misc_feature 20007..20201 FT /note="Pfam match to entry PF00989 PAS, PAS domain, score FT 34.90, E-value 1.8e-06" FT misc_feature 20358..20882 FT /note="Pfam match to entry PF00990 DUF9, Domain of unknown FT function, score 167.40, E-value 2.3e-46" FT misc_feature 20922..21662 FT /note="Pfam match to entry PF00563 DUF2, Domain of unknown FT function 2, score 152.30, E-value 8.3e-42" FT CDS 22117..23958 FT /transl_table=11 FT /gene="SCO5512" FT /gene_synonym="SC8D9.24" FT /gene_synonym="ilvB" FT /product="acetolactate synthase" FT /note="SC8D9.24, ilvB, acetolactate synthase, len: 613aa; FT high level of similarity to many eg. TR:Q59816 FT (EMBL:L39268) ilvB, acetolactate synthase from the ilvBNC FT gene cluster of Streptomyces avermitilis (617 aa) fasta FT scores; opt: 3558, z-score: 3786.3, E(): 0, (87.2% identity FT in 619 aa overlap). Contains PS00187 Thiamine pyrophosphate FT enzymes signature and Pfam match to entry PF00205 FT TPP_enzymes, Thiamine pyrophosphate enzymes, score 899.00, FT E-value 3.2e-278." FT /db_xref="GOA:Q9Z567" FT /db_xref="HSSP:1JSC" FT /db_xref="InterPro:IPR012000" FT /db_xref="UniProtKB/TrEMBL:Q9Z567" FT /protein_id="CAB37588.1" FT /translation="MTEQATGAHPQPRPRSGGQSAPEHVTGAQSLIRSLEEVGADTVFG FT IPGGTILPAYDPLMDSTRVRHVLVRHEQGAGHAATGYAQATGKVGVCMATSGPGATNLV FT TPIADANLDSVPLVAITGQVVSSAIGTDAFQEADIVGITMPITKHSFLVTKAEDIPRVI FT AQAFHIASTGRPGPVLVDIPKDILQKKTTFSWPPVMDLPGYRPVTKPHAKQIREAAKLI FT SAAKRPVLYVGGGVLKAKATAELKVLAELTGAPVTTTLMALGAFPDSHPLHVGMPGMHG FT AVTAVTALQKADLIVALGARFDDRVTGKLDSFAPHAKIVHADIDPAEIGKNRAADVPIV FT GDAREVVADLVQAVQKEHDEGNKGDYSAWWKDLSRWRDTYPLGYDQPEDGSLSPQQVIE FT RIGQLAPEGTIFAAGVGQHQMWAAHFVQYEKPATWLNSGGAGTMGYAVPAAMGAQAGMP FT GRTVWAIDGDGCFQMTNQELTTCALNNIPIKVAVINNGALGMVRQWQTLFYNQRYSNTV FT LHSGPDDVNPEARGTRVPDFVKLSEAMGCYAIRCEDPADLDKVIEEANSVNDRPVVVDF FT IVHEDAMVWPMVAAGTSNDEILAARDVRPDFGDNEDD" FT misc_feature 22219..23844 FT /note="Pfam match to entry PF00205 TPP_enzymes, Thiamine FT pyrophosphate enzymes, score 899.00, E-value 3.2e-278" FT misc_feature 23467..23526 FT /note="PS00187 Thiamine pyrophosphate enzymes signature." FT CDS 23980..24504 FT /transl_table=11 FT /gene="SCO5513" FT /gene_synonym="ilvN" FT /gene_synonym="SC8D9.25" FT /product="acetolactate synthase small subunit" FT /note="SC8D9.25, ilvN, acetolactate synthase small subunit, FT len: 174 aa; high level of similarity to many e.g. FT TR:Q59817 (EMBL:L39268) IlvN, acetolactate synthase small FT subunit from the ilvBNC gene cluster of Streptomyces FT avermitilis (176 aa) fasta scores; opt: 884, z-score: FT 1056.9, E(): 0, (86.4% identity in 176 aa overlap)." FT /db_xref="GOA:Q9Z566" FT /db_xref="InterPro:IPR019455" FT /db_xref="UniProtKB/TrEMBL:Q9Z566" FT /protein_id="CAB37589.1" FT /translation="MSKHTLSVLVENTPGVLARITALFSRRGFNIDSLAVGVTEHPDIS FT RITIVVSVEDFPLEQVTKQLNKLVNVLKIVELEPTQAVQRELVLVKVRSDNETRSQIVE FT IVQLFRAKTVDVSPEAVTIEATGSSDKLTAMLRMLEPYGIKELVQSGTIAIGRGARSIT FT DRSLRALDRSA" FT CDS 24643..25641 FT /transl_table=11 FT /gene="SCO5514" FT /gene_synonym="ilvC" FT /gene_synonym="SC8D9.26" FT /product="acetolactate synthase small subunit" FT /note="SC8D9.26, ilvC, acetohydroxy acid isomeroreductase, FT len: 174 aa; high level of similarity to many e.g. FT TR:Q59818 (EMBL:L39268) IlvC, acetohydroxy acid FT isomeroreductase from the ilvBNC gene cluster of FT Streptomyces avermitilis (333 aa) fasta scores; opt: 2075, FT z-score: 2404.5, E(): 0, (94.6% identity in 333 aa FT overlap)." FT /db_xref="GOA:Q9Z565" FT /db_xref="HSSP:1NP3" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/Swiss-Prot:Q9Z565" FT /protein_id="CAB37590.1" FT /translation="MAELFYDADADLSIIQGRKVAVIGYGSQGHAHALSLRDSGVDVRV FT GLHEGSKSKAKAEEQGLRVVPVAEAAAEADVIMILVPDPIQAEVYEKDIKDNLKDGDAL FT FFGHGLNIRYGFIKPPAGVDVCMVAPKGPGHLVRRQYEEGRGVPCIAAVEQDATGNAFA FT LALSYAKGIGGTRAGVIKTTFTEETETDLFGEQAVLCGGTAALVKAGFETLTEAGYQPE FT IAYFECLHELKLIVDLMYEGGLEKMRWSISETAEWGDYVTGPRIITDATKAEMKKVLAE FT IQDGTFAKNWMDEYHGGLKKYNEYKKQDSEHLLETTGKELRKLMSWVDEEA" FT CDS 25860..27449 FT /transl_table=11 FT /gene="SCO5515" FT /gene_synonym="serA" FT /gene_synonym="SC8D9.27" FT /product="probable D-3-phosphoglycerate dehydrogenase" FT /note="SC8D9.27, serA, D-3-phosphoglycerate dehydrogenase, FT len: 529 aa; member of a family including egs. FT SW:SERA_MYCLE putative SerA, D-3-phosphoglycerate FT dehydrogenase from Mycobacterium leprae (528 aa) fasta FT scores; opt: 1889, z-score: 2032.0, E(): 0, (56.9% identity FT in 524 aa overlap) and SW:SERA_BACSU SerA, FT D-3-phosphoglycerate dehydrogenase from Bacillus subtilis FT (525 aa) fasta scores; opt: 1176, z-score: 1266.5, E(): 0, FT (39.7% identity in 529 aa overlap). Contains PS00065 FT D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding FT signature, PS00670 D-isomer specific 2-hydroxyacid FT dehydrogenases signature 2 and Pfam match to entry PF00389 FT 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenases, FT score 256.90, E-value 7e-105." FT /db_xref="GOA:Q9Z564" FT /db_xref="HSSP:1PSD" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9Z564" FT /protein_id="CAB37591.1" FT /translation="MSSKPVVLIAEELSPATVDALGPDFEIRHCNGADRAELLPAIADV FT DAILVRSATKVDAEAVAAAKKLKVVARAGVGLDNVDVSAATKAGVMVVNAPTSNIVTAA FT ELACGLIVATARNIPQANAALKNGEWKRSKYTGVELAEKTLGVVGLGRIGALVAQRMSA FT FGMKVVAYDPYVQPARAAQMGVKVLSLDELLEVSDFITVHLPKTPETLGLIGDEALRKV FT KPSVRIVNAARGGIVDEEALYSALKEGRVAGAGLDVYAKEPCTDSPLFEFDQVVATPHL FT GASTDEAQEKAGIAVAKSVRLALAGELVPDAVNVQGGVIAEDVKPGLPLAERLGRIFTA FT LAGEVAVRLDVEVYGEITQHDVKVLELSALKGVFEDVVDETVSYVNAPLFAQERGVEVR FT LTTSSESPEHRNVVIVRGTLSDGEEVSVSGTLAGPKHLQKIVAIGEYDVDLALADHMVV FT LRYEDRPGVVGTVGRIIGEAGLNIAGMQVARATVGGEALAVLTVDDTVPSGVLAEVAAE FT IGATSARSVNLV" FT misc_feature 26085..26699 FT /note="Pfam match to entry PF00389 2-Hacid_DH, D-isomer FT specific 2-hydroxyacid dehydrogenases, score 256.90, FT E-value 7e-105" FT misc_feature 26292..26375 FT /note="PS00065 D-isomer specific 2-hydroxyacid FT dehydrogenases NAD-binding signature." FT misc_feature 26436..26504 FT /note="PS00670 D-isomer specific 2-hydroxyacid FT dehydrogenases signature 2." FT CDS complement(27515..29080) FT /transl_table=11 FT /gene="SCO5516" FT /gene_synonym="SC8D9.28c" FT /product="putative integral membrane efflux protein" FT /note="SC8D9.28c, probable integral membrane efflux FT protein, len: 521aa; Similar to many efflux proteins FT (confirmed and proposed) most of which appear to be FT dedicated to drug resistance/export egs. TR:O33968 FT (EMBL:U80063) putative transmembrane, proton-dependent FT transport protein from Streptomyces cinnamomeus (519 aa) FT fasta scores; opt: 1342, z-score: 1386.9, E(): 0, (46.5% FT identity in 503 aa overlap) and TR:O52557 (EMBL:AF040570) FT rifamycin efflux protein from Amycolatopsis mediterranei FT (522 aa) fasta scores; opt: 988, z-score: 1022.7, E(): 0, FT (38.0% identity in 523 aa overlap). Contains multiple FT potential membrane spanning regions." FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9Z563" FT /protein_id="CAB37592.1" FT /translation="MRTVAAMTTNPPRAGRREWTALAVLMLPLLLVSMDVSVLFFAIPE FT ISADLEPSGTQQLWIFDIYGFVLAGLLMTMGSLGDRIGRRRLLLVGAAAFGAASLLAAY FT AHTAETLIAARAVLGIGGATLMPSTMALVRTMFTDPAQRAKAIGLWSGVMTAGIALGSV FT MSGVLVEHFWWGSVFLVNLPAMALLLILGPVLLPESKNPSPGRFDLLSVPLSMAAVLPV FT VYGLKELPSEGWNVRYVVSITVGLLFAALFVHRQRTAASPMISPALFRGHGFTPAVVLN FT LVSAFGMMGSSYFTTQYLQSVLDKSALEAALWALLPSVFIGFAAPLAMRLVQLGVERAY FT VVAGGFVVAACGYALLACAGTDSLWLVLAACGVMAGGIVAVMSQLTDLALSSAPVEKAG FT AASSLMETGTEFGGALSMAVLGSVGTAVYHHEMPASAPDAARETLGGALSVAARLPGSA FT GEALATAAREAFTDGMRGASIAGAVLLLAAALPAARAMRGIRVRENAATENAGQADSLS FT PSGV" FT CDS 29146..29736 FT /transl_table=11 FT /gene="SCO5517" FT /gene_synonym="SC8D9.29" FT /product="putative transcriptional regulator" FT /note="SC8D9.29, possible transcriptional regulator, len: FT 196 aa; some similarity to many e.g. TR:O34381 FT (EMBL:Z99112) PksA, transcriptional regulator, involved in FT regulation of the polyketide synthase operon in Bacillus FT subtilis (205 aa) fasta scores; opt: 108, z-score: 141.0, FT E(): 1.5, (32.1% identity in 56 aa overlap) and TR:O86510 FT (EMBL:AL031124) putative transcriptional regulator from FT Streptomyces coelicolor (200 aa) fasta scores; opt: 135, FT z-score: 173.7, E(): 0.023, (30.9% identity in 139 aa FT overlap)." FT /db_xref="GOA:Q9Z562" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9Z562" FT /protein_id="CAB37593.1" FT /translation="MGHREDLLEGAKRCLLEKGFARTTARDIVKESRTNLASIGYHYGS FT KDVLLAQAYIELIEGMGGAFEGEGPALDDTEPGSVERFQQVWSNIIGTMREPGSIWRLS FT MEVLVMGDRMPELRDHLGRAQREAGRGIIPLLMGGREEDVTDETTDTLGTFYVTLMTGL FT IAQWTFDPKSAPDADALTEGLRRVIGAATGDAP" FT CDS complement(29717..30964) FT /transl_table=11 FT /gene="SCO5518" FT /gene_synonym="SC8D9.30c" FT /product="putative transcriptional regulator" FT /note="SC8D9.30c, possible transcriptional regulator, len: FT 521 aa; some similarity to TR:Q00509 (EMBL:X63451) SrmR, FT regulatory gene governing the expression of a polyketide FT synthase gene in Streptomyces ambofaciens (604 aa) fasta FT scores; opt: 142, z-score: 152.0, E(): 0.37, (28.1% FT identity in 228 aa overlap). Also similar to TR:E1359977 FT (EMBL:AL034492) putative transcriptional regulator from FT Streptomyces coelicolor (569 aa) fasta scores; opt: 204, FT z-score: 216.7, E(): 9.1e-05, (28.6% identity in 448 aa FT overlap). Contains possible helix-turn-helix at 367-388 aa FT (+2.83 SD)." FT /db_xref="UniProtKB/TrEMBL:Q9Z561" FT /protein_id="CAB37594.1" FT /translation="MRQNARVTSDSRGSAGTGGTRGDYQELVDELSELLGAPATLENRD FT FELIAFGAYDSEGDLDPSALDPVRTRSILTRRSTAAVRAWFESFGITRATGPVRIPPTP FT EAGVYRGRTCLPVRHRGVVLGYVWLLDTDPGPTERQLAAAMEVTGRIGALLADEAQHGA FT DLSRELRAVLTAERDWQRDMAVAELRSALGARAETPHAVVCVAPWPSADPDDAPSVRTV FT PGATALCTVPWGVSAVSLALLVRLRSAEVQTPATSAAGRLLERAGALGVGGPSGAAGGV FT AAGVSAPRTGLADLGAAWSEASAAARAARAEERFGPVAQWTSIGAFRLLTSLPPRSADD FT PAVRALLSPAHRELARTAEVYLDCAGQAGRTAAELGVHRQTLYYRLSRVEQLTGLDLDD FT GEDRLLLHMALKARRL" FT CDS 31130..32056 FT /transl_table=11 FT /gene="SCO5519" FT /gene_synonym="SC8D9.31" FT /product="conserved hypothetical protein" FT /note="SC8D9.31, unknown, len: 308aa; similar to proteins FT of undefined function eg. TR:O50444 (EMBL:AL010186) from FT Mycobacterium tuberculosis (329 aa) fasta scores; opt: 984, FT z-score: 1121.1, E(): 0, (50.0% identity in 312 aa FT overlap)." FT /db_xref="GOA:Q9Z560" FT /db_xref="InterPro:IPR015590" FT /db_xref="UniProtKB/TrEMBL:Q9Z560" FT /protein_id="CAB37595.1" FT /translation="MLGPVILAASRSDRMRRLVSAAPVTKPVVDRFIPGETVDQIVPIV FT RDLTDQGLELTMDVVGEDITTPAQAEAARDAYLELIDRLKPLELGTRAEMSVKLSMFGQ FT ALDGGHELALANVRPVVEAAAEIGTTVTLDAEDHTTLDSMFAIHEELRKDFPQTGCVIQ FT AYLFRTEADARRLADSGSRVRLVKGAYKEPAEVAYQQRHEIDKAYVRILRTLMEGEGYP FT MIGSHDPRLISIGQELARTAGRKLDEYEFQMLYGIRGDEHLRLAAEGHRMRVYTAYGTD FT WYGYFMRRLAEKPANLRFFARSMVSKG" FT CDS 32103..33743 FT /transl_table=11 FT /gene="SCO5520" FT /gene_synonym="SC1C2.01" FT /gene_synonym="SC8D9.32" FT /product="delta-1-pyrroline-5-carboxylate dehydrogenase" FT /note="SC1C2.01, probable delta-1-pyrroline-5-carboxylate FT dehydrogenase, partial CDS, len >408 aa; similar to many FT e.g. TR:O50443 (EMBL:AL010186) FT delta-1-pyrroline-5-carboxylate dehydrogenase (M. FT tuberculosis) (543 aa), fasta scores; opt: 1753 z-score: FT 2214.2 E(): 0, 65.1% identity in 407 aa overlap, and FT PUT2_HUMAN delta-1-pyrroline-5-carboxylate dehydrogenase FT (563 aa), fasta scores; opt: 1273 z-score: 1730.4 E(): 0, FT 48.5% identity in 408 aa overlap. Contains PS00687 and FT PS00070 Aldehyde dehydrogenases glutamic acid active site FT and cysteine active site and Pfam match to entry PF00171 FT aldedh, Aldehyde dehydrogenases, score 114.70, E-value FT 1.8e-30" FT /note="SC8D9.32, partial CDS, probable FT pyrroline-5-carboxylate dehydrogenase, len: >182aa; similar FT to many eg. TR:O50443 (EMBL:AL010186) RocA, probable FT pyrroline-5-carboxylate dehydrogenase from Mycobacterium FT tuberculosis (543 aa) fasta scores; opt: 843, z-score: FT 1024.6, E(): 0, (66.5% identity in 182 aa overlap) and FT SW:PUT2_AGABI PruA, delta 1-pyrroline-5-carboxylate FT dehydrogenase from Agaricus bisporus (common mushroom) (546 FT aa) fasta scores; opt: 521, z-score: 634.9, E(): 4.7e-28, FT (44.5% identity in 182 aa overlap)." FT /db_xref="GOA:Q8CJR1" FT /db_xref="InterPro:IPR016162" FT /db_xref="UniProtKB/TrEMBL:Q8CJR1" FT /protein_id="CAD55356.1" FT /translation="MDAVTQVPTPVNEPVHGYAPGSPERARLEAKLKELADNPIDLPCT FT IGGEKRMGGGERFDVVQPHNHKSRLGTYANATQADAQDAIDAALAAAPAWRAMSFDDRA FT AIILRAAELLSGPWRETIAASTMLGQSKTAQQAEIDSPCELIDFWRFNVHYARNILAEQ FT PPANSQGVWNRMDHRPLEGFVYAITPFNFSAIAANLPTAPALMGNVVVWKPSPTQTHAA FT VLLMQLLEEAGLPKGVINLVTGDGIAVSEVALEHRDLAGIHFTGSTKTFQHLWKTVGNN FT IEKYRTYPRLVGETGGKDFLVAHPSADRAVLKTALTRGAFEYQGQKCSATSRAYIPASI FT WNDGFKEEFAAEVDYLTMGDVTDLSNFIGAVIDERSFAKNKAAIDRAKEDETCTIVAGG FT SYDDSVGYFVRPTVVECTDPENEVFRTEYFGPFLAVHVYDDSADDAYDAMLTQMESVSD FT YALTGSVISNDRAAAAYTMEKLRYAAGNFYINDKSTGAVVGQQPFGGGRASGTNDKAGA FT PQNLMRWTLTRAIKETLVAPTDYTYPHMG" FT misc_feature 32516..36322 FT /note="true overlap with cosmid 8D9" FT misc_feature 32517..33704 FT /note="Pfam match to entry PF00171 aldedh, Aldehyde FT dehydrogenases, score 114.70, E-value 1.8e-30" FT misc_feature 32979..33002 FT /note="PS00687 Aldehyde dehydrogenases glutamic acid active FT site" FT misc_feature 33063..33098 FT /note="PS00070 Aldehyde dehydrogenases cysteine active FT site" FT stem_loop 33761..33798 FT /note="hairpin_loop with 18bp stem" FT RBS 34037..34042 FT /note="possible RBS upstream of SC1C2.02" FT CDS 34052..34183 FT /transl_table=11 FT /gene="SCO5521" FT /gene_synonym="SC1C2.02" FT /product="hypothetical protein SC1C2.02" FT /note="SC1C2.02, questionable ORF, len: 43 aa" FT /db_xref="UniProtKB/TrEMBL:O86503" FT /protein_id="CAA19969.1" FT /translation="MAETTVRRRVRHLSRTSDSDRKNAAAALQRSLDRRDNGGATGH" FT CDS 34259..35302 FT /transl_table=11 FT /gene="SCO5522" FT /gene_synonym="leuB" FT /product="3-isopropylmalate dehydrogenase" FT /note="SC1C2.03, leuB, probable 3-isopropylmalate FT dehydrogenase, len: 347 aa; similar to e.g. LEU3_CORGL FT 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (340 aa), FT fasta scores; opt: 1450 z-score: 1318.1 E(): 0, 68.0% FT identity in 338 aa overlap. Contains PS00470 Isocitrate and FT isopropylmalate dehydrogenases signature and Pfam match to FT entry PF00180 isodh, Isocitrate and isopropylmalate FT dehydrogenases, score 356.60, E-value 1.3e-105" FT /db_xref="GOA:O86504" FT /db_xref="HSSP:2AYQ" FT /db_xref="InterPro:IPR001804" FT /db_xref="UniProtKB/Swiss-Prot:O86504" FT /protein_id="CAA19970.1" FT /translation="MSRSLNLAVIPGDGIGQEVVAEGLKVLSAVLPQDVKLETKEFDFG FT ARRYHATGETLTDADLDALKAHDAILLGAIGDPSVPSGVLERGFLLKLRFAFDHHVNLR FT PSKLLPGVATPLAGQPEIDFVVVREGTEGPYTGNGGTIRKGTEHEVATEVSVNTAYGVE FT RVVRDAFARAQARPRKKLTLVHKNNVLTFAGHLWTNIFNKVAAEYPEVTTDYLHVDAAT FT IFLVTDPARFDVIVTDNLFGDIITDLAAAVSGGIGVAASGNINPSGDFPSMFEPVHGSA FT PDIAGQGKADPTATVLSVALLLRHLGYEDEAARIEDAVSADLGERGDLPARSTSEIGDT FT LAARVAG" FT misc_feature 34274..35281 FT /note="Pfam match to entry PF00180 isodh, Isocitrate and FT isopropylmalate dehydrogenases, score 356.60, E-value FT 1.3e-105" FT misc_feature 34973..35032 FT /note="PS00470 Isocitrate and isopropylmalate FT dehydrogenases signature" FT RBS 35553..35557 FT /note="possible RBS upstream of ilvE" FT CDS 35567..36655 FT /transl_table=11 FT /gene="SCO5523" FT /gene_synonym="ilvE" FT /product="branched-chain amino acid aminotransferase" FT /note="SC1C2.04, ilvE, probable branched-chain amino acid FT aminotransferase, len: 362 aa; similar to many, e.g. FT ILVE_BACSU putative branched-chain amino acid FT aminotransferase (362 aa), fasta scores; opt: 1047 z-score: FT 1401.5 E(): 0, 44.7% identity in 360 aa overlap. Contains FT PS00770 Aminotransferases class-IV signature" FT /db_xref="GOA:O86505" FT /db_xref="HSSP:1KT8" FT /db_xref="InterPro:IPR005786" FT /db_xref="UniProtKB/Swiss-Prot:O86505" FT /protein_id="CAA19971.1" FT /translation="MTTPTIELKPSAHPLSDSERAAILANPGFGRHFTDHMVTIKWTEG FT RGWHDGQLVPYAPLSLDPATMVLHYAQEIFEGLKAYRRPDGSVATFRPEKNGARFQASS FT RRLGMPELPVDTFIEACDALVAQDEKWVPAHGGEESLYLRPFMIATEVGLGVRPANEYL FT FIVIASPAGAYFPGGVKPVSIWVSEDRVRAVPGGMGDAKTGGNYAASLLAQAEAAAKGC FT DQVCYLDAIERKWVEELGGMNLYFVYGNKIVTPSLTGSILEGVTRDSLLTVARDLGYEA FT EEGRVSVDQWQRDSENGTLTEVFACGTAAVITPVGTVKRAGAQWQQSGGETGEVTQRLR FT DALLDIQRGTVADPHGWMHTLA" FT misc_feature 36278..36367 FT /note="PS00770 Aminotransferases class-IV signature" FT CDS complement(36729..38159) FT /transl_table=11 FT /gene="SCO5524" FT /gene_synonym="SC1C2.05c" FT /product="putative transmembrane transport protein" FT /note="SC1C2.05c, possible transmembrane transport protein, FT len: 476 aa; similar to e.g. B. subtilis TR:P94369 FT (EMBL:D83026) yxlA (homologous to purine-cytosine FT permease) (457 aa), fasta scores; opt: 235 z-score: 377.4 FT E(): 9e-14, 24.0% identity in 475 aa overlap" FT /db_xref="GOA:O86506" FT /db_xref="InterPro:IPR001248" FT /db_xref="UniProtKB/TrEMBL:O86506" FT /protein_id="CAA19972.1" FT /translation="MPIEQRGVDTIPEAERTSGPRDLVSILLGSNLCLGVIVFGWLPPS FT FGLGWWASVSSVVAGTVVGTVFTAPLALISLRTGTNLSTSSGAQFGVRGRLVGSVVGLL FT LALGYTALTVWIGGDVMAGVLGRLFGLPQGGATYAVVYGLLAAATVAGAVYGYRVLLAM FT SRVLAYGMTALLVLGVIAYAPDFTTAALPEAGGYLLGGFWPTWLLAAVAAGLSGPIAFI FT TLLGDYTRYISPARHSSRRVLRATWLGLTLGLLVPQLFGTFTAYAAGAALDYAGPLVDA FT SPTWYLVPLLLAASAGSVGNAGLMLYSMGLDLDAILPRASRARATCAVAVVATACVFAG FT HYAWQAQSAMTSFVLLLTAIGTPWAVITMIGSVRCGGVYDADALQVFNRRARGGIYWYR FT SGWNVPATAAWAVGALVGVLAVSLPSYEGPLLSLTGGVDCSFLLSGLVGGAVYVLLPQP FT RAASPKEPGVGNLSPSGV" FT RBS complement(38168..38172) FT /note="possible RBS upstream of SC1C2.05c" FT RBS 38288..38295 FT /note="possible RBS upstream of ureAB" FT CDS 38304..38987 FT /transl_table=11 FT /gene="SCO5525" FT /gene_synonym="ureAB" FT /product="fusion of urease beta and gamma subunits" FT /note="SC1C2.06, ureAB, probable fusion of urease beta and FT gamma subunits, len: 227 aa; N-terminus is similar to UreA FT e.g. URE3_ECOLI urease gamma subunit (EC 3.5.1.5) (100 aa), FT fasta scores; opt: 300 z-score: 398.9 E(): 5.7e-15, 44.4% FT identity in 99 aa overlap; C-terminus is similar to ureB FT e.g. URE2_YEREN urease beta subunit (EC 3.5.1.5) (163 aa), FT fasta scores; opt: 303 z-score: 390.6 E(): 1.6e-14, 40.9% FT identity in 132 aa overlap. This fusion also exists in FT Helicobacters, where it is called the urease alpha subunit; FT URE1_HELFE urease alpha subunit (EC 3.5.1.5) (237 aa), FT fasta scores; opt: 529 z-score: 603.4 E(): 2.3e-26, 42.0% FT identity in 226 aa overlap. Contains Pfam matches to entry FT PF00547 urease_gamma, Urease, gamma subunit, score 116.70, FT E-value 7.9e-35 and to entry PF00699 Urease_beta, Urease FT beta subunit, score 91.80, E-value 1.4e-23" FT /db_xref="GOA:O86507" FT /db_xref="HSSP:1EJX" FT /db_xref="InterPro:IPR008223" FT /db_xref="UniProtKB/Swiss-Prot:O86507" FT /protein_id="CAA19973.1" FT /translation="MRLTPTERDRLLLFGAAELARARRARGLRLNVPEATALIADTVCE FT AARDGARLAQAIERARSVLGPDDVLPGVADVVTEVHVEAVFDDGSRLAVVADPVGGGGL FT GDDAPGALLPGHDRPEPEAALRLPVTNTATVPVSVTSHFHFFEANPRLDFDRGRAYGMR FT LAVPAGSSVRFGPGERVEVGLVPIGGARVAIGFAGLVDGPLDAPGAREEALRRAAACGY FT LGADR" FT misc_feature 38307..38600 FT /note="Pfam match to entry PF00547 urease_gamma, Urease, FT gamma subunit, score 116.70, E-value 7.9e-35" FT misc_feature 38658..38867 FT /note="Pfam match to entry PF00699 Urease_beta, Urease beta FT subunit., score 91.80, E-value 1.4e-23" FT misc_feature 38984..40657 FT /note="Pfam match to entry PF00449 urease, Urease, score FT 758.30, E-value 3.3e-224" FT CDS 38984..40660 FT /transl_table=11 FT /gene="SCO5526" FT /gene_synonym="ureC" FT /product="urease alpha subunit" FT /note="SC1C2.07, ureC, probable urease alpha subunit, len: FT 558 aa; similar to many e.g. URE1_YEREN urease alpha FT subunit (EC 3.5.1.5) (571 aa), fasta scores; opt: 1676 FT z-score: 1972.3 E(): 0, 45.2% identity in 564 aa overlap. FT Contains PS01120 Urease nickel ligands signature and Pfam FT match to entry PF00449 urease, Urease, score 758.30, FT E-value 3.3e-224" FT /db_xref="GOA:O86508" FT /db_xref="HSSP:1EJX" FT /db_xref="InterPro:IPR011612" FT /db_xref="UniProtKB/Swiss-Prot:O86508" FT /protein_id="CAA19974.1" FT /translation="MTIDPYAYAAAHGPRAGDRLRLGDSGLVIRVESDAQHYGDEFLAG FT FGKTARDGLHLKAAAVRDTCDVVISNVVVIDAVQGIRKVSIGIREGRVHAIGRAGNPDT FT LDGVDVVVGTGTSIVSGEGLIATAGAVDTHVHLLSPRIMEASLASGVTTIIGQEFGPVW FT GVGVNSPWALKHAFGAFDAWPVNIGFLGRGSSSHEAPLIEALAEGGASGFKVHEDMGAH FT TRALDTALRVAEEHDVQVALHSDGLNECLSVEDTLRVLDGRTIHAFHIEGCGGGHVPNV FT LKMAGVPHVIGSSTNPTLPFGRDAVAEHYGMIVSVHDLKTDLPGDAAMARDRIRAGTMG FT AEDVLHDLGAIGITSSDAQGMGRAGETVRRTFAMAGKMKAQFGAEGDDDNARVLRYIAK FT LTINPALAHGLAHEVGSIEVGKLADLVLWRPDHFGAKPQLVLKSGFPAYGVVGDPNAAT FT DTCEPLVLGPQFGAHGATPAEISVAFVAQAALDQGGDTMPTRRRRVAVRGTRGIGPADL FT RLNSRTGAVDVDQRTGLVTLDGDPLRSEPAESVSLNRLYFL" FT misc_feature 39362..39403 FT /note="PS01120 Urease nickel ligands signature" FT CDS 40711..41730 FT /transl_table=11 FT /gene="SCO5527" FT /gene_synonym="SC1C2.08" FT /product="conserved hypothetical protein SC1C2.08" FT /note="SC1C2.08, unknown, len: 339 aa; similar to two FT hypothetical proteins TR:O41120 (EMBL:U42580) A638R protein FT from Paramecium bursaria chlorella virus 1 (360 aa), fasta FT scores; opt: 635 z-score: 688.3 E(): 4.4e-31, 35.0% FT identity in 343 aa overlapTR:O24890 (EMBL:AE000526) HP0049 FT from Helicobacter pylori (330 aa)opt: 416 z-score: 316.9 FT E(): 2.1e-10, 25.5% identity in 337 aa overlap" FT /db_xref="GOA:O86509" FT /db_xref="InterPro:IPR007466" FT /db_xref="UniProtKB/Swiss-Prot:O86509" FT /protein_id="CAA19975.1" FT /translation="MTFRMPPEWAPHERTWMAWPGPNATFTDAEELAGARAAWASVARA FT VRRFEPVTMVHGPGQAATARELLGPDVDLVERELDDAWMRDIGPTFVTDGRGGLAAVDW FT VFNGWGAQDWARWEHDAEIARHVADLAAAPVLSSPLVNEGGAIHVDGEGTVLLTDTVQL FT GSGRNPGWSREEVEAEIHAKLGTTTAIWLPHGLAGDYGRYGTQGHVDIVAAFARPGTVV FT VHSQRDPRHPDHERSQLYLEILRGRTDARGRRLEVVEVPAPTVLKDEEGEWADYSYINH FT YVCNGGVVLCAFGDPNDELAAGIFRRLFPERTVTLVDARTIFAGGGGIHCITQQQPRT" FT RBS 41739..41742 FT /note="possible RBS upstream of SC1C2.09" FT CDS 41748..42350 FT /transl_table=11 FT /gene="SCO5528" FT /gene_synonym="SC1C2.09" FT /product="putative transcriptional regulator" FT /note="SC1C2.09, possible transcriptional regulator, len: FT 200 aa; some similarity to e.g. TR:O34381 (EMBL:Z99112) FT transcriptional regulator PksA from Bacillus subtilis (205 FT aa), fasta scores; opt: 182 z-score: 206.5 E(): 0.0003, FT 26.5% identity in 185 aa overlap. Contains probable FT helix-turn-helix motif at aa 32-53 (Score 1136, +3.06 SD) FT and Pfam match to entry PF00440 tetR, Bacterial regulatory FT proteins, tetR family, score 35.50, E-value 4.1e-08" FT /db_xref="GOA:O86510" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:O86510" FT /protein_id="CAA19976.1" FT /translation="MAGGGRRQAPPREDVLAAAMEMIAERGLEKLTMAALGREVGMSSG FT HLLYYFGSKDELLLRTLEWSEGRLGAERGRLLTRPGTARERLGAYVDLYVPDGHRDPHW FT TLWLEVWNHSQNAPDEARDRQAAIEGAWHRDLTALLAEGISRGEFRAVDPDRFASRLRA FT LLDGFAIHVAIGLRGTDRAQVLGHVRDFLADGLYGRD" FT misc_feature 41790..41930 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 35.50, E-value FT 4.1e-08" FT RBS 42654..42658 FT /note="possible RBS upstream of SC1C2.10" FT CDS 42669..44273 FT /transl_table=11 FT /gene="SCO5529" FT /gene_synonym="SC1C2.10" FT /product="putative 2-isopropylmalate synthase" FT /note="SC1C2.10, putative 2-isopropylmalate synthase, len: FT 534 aa; similar to e.g. LEU1_BACSU 2-isopropylmalate FT synthase (leuA) (EC 4.1.3.12) (A (518 aa), fasta scores; FT opt: 563 z-score: 585.3 E(): 2.4e-25, 28.1% identity in 523 FT aa overlap, and to e.g. NIFV_FRASP homocitrate synthase (EC FT 4.1.3.21) (401 aa), fasta scores; opt: 316 z-score: 554.5 FT E(): 1.2e-23, 33.0% identity in 358 aa overlap. Contains FT PS00815 Alpha-isopropylmalate and homocitrate synthases FT signature 1 and Pfam match to entry PF00682 HMGL-like, FT HMGL-like, score 126.90, E-value 3.7e-34" FT /db_xref="GOA:O86511" FT /db_xref="InterPro:IPR000891" FT /db_xref="UniProtKB/Swiss-Prot:O86511" FT /protein_id="CAA19977.1" FT /translation="MTATSELDDSFHVFDTTLRDGAQREGINLTVADKLAIARHLDDFG FT VGFIEGGWPGANPRDTEFFARARQEIDFKHAQLVAFGSTRRAGANAAEDHQVKALLDSG FT AQVITLVAKSHDRHVELALRTTLDENLAMVADTVSHLKAQGRRVFVDCEHFFDGYRANP FT EYAKSVVRTASEAGADVVVLCDTNGGMLPAQIQAVVATVLADTGARLGIHAQDDTGCAV FT ANTLAAVDAGATHVQCTANGYGERVGNANLFPVVAALELKYGKQVLPEGRLREMTRISH FT AIAEVVNLTPSTHQPYVGVSAFAHKAGLHASAIKVDPDLYQHIDPELVGNTMRMLVSDM FT AGRASIELKGKELGIDLGGDRELVGRVVERVKERELAGYTYEAADASFELLLRAEAEGR FT PLKYFEVESWRAITEDRPDGSHANEATVKLWAKGERIVATAEGNGPVNALDRSLRVALE FT KIYPELAKLDLVDYKVRILEGVHGTQSTTRVLISTSDGTGEWATVGVAENVIAASWQAL FT EDAYTYGLLRAGVAPAE" FT misc_feature 42717..43565 FT /note="Pfam match to entry PF00682 HMGL-like, HMGL-like, FT score 126.90, E-value 3.7e-34" FT misc_feature 42720..42770 FT /note="PS00815 Alpha-isopropylmalate and homocitrate FT synthases signature 1" FT CDS 44338..45690 FT /transl_table=11 FT /gene="SCO5530" FT /gene_synonym="SC1C2.11" FT /product="putative membrane protein" FT /note="SC1C2.11, putative membrane protein, len: 450 aa; FT contains probable hydrophobic membrane spanning regions and FT highly Gly-rich C-terminus" FT /db_xref="UniProtKB/TrEMBL:O86512" FT /protein_id="CAA19978.1" FT /translation="MKGVRAQVLIRLLVAPVVAALAVLLAGAPGAQAETGVSEIGAALR FT ESPVYVDPAASGLLSRSDADALADKIEDAGEPVFVAVLPAGYPTENLFQNLRTETGITG FT LYGVRLGDRFDARADSSVLSRQGVHNLVTAVQGAGDPKAQLNDFVDDALRSVRGSAPSS FT WDSGGGSAPTGALITAGAVVVLGGAGVYAVSRRSRHRREAEQRAALERLRVVVDEDITA FT FGEELDRLDFHPAEPGADDAMRADYERALDAYEQAKTYMADARKPEDVRAVTQAVEDGR FT FSLAQLAARREGRPLPERRPPCFFDPRHGPSVADATWTPPGGTTRRVPVCAADQARLSD FT GRDPMIREVDTEYGRRPYWDAGPAYGPWAGGYFGGGILPGLLVGTMLGGMMAGPAYGAG FT YGTGYGDFGGYEGGDVSGGDFDPGDFGGGFGGGDFGGGGGFGGGGDFGGGF" FT CDS complement(45708..46712) FT /transl_table=11 FT /gene="SCO5531" FT /gene_synonym="SC1C2.12c" FT /product="putative integral membrane protein" FT /note="SC1C2.12c, probable integral membrane protein, len: FT 334 aa; similar to TR:Q98DR8 (EMBL:AP003004) Rhizobium loti FT (Mesorhizobium loti) putative integral membrane protein FT MLL4580, 308 aa; fasta scores: opt: 503 Z-score: 515.3 E(): FT 4.5e-21; 33.904% identity in 292 aa overlap. COntains FT possible hydrophobic membrane spanning regions" FT /db_xref="GOA:O86513" FT /db_xref="InterPro:IPR000620" FT /db_xref="UniProtKB/TrEMBL:O86513" FT /protein_id="CAA19979.1" FT /translation="MNVLLSAAFVLCWSSGFIGAKLGAQTAATPTLLMWRFLPLAVALV FT AAAAVSRAAWRGLTPRDAGRQIAIGALSQSGYLLSVYYAIELGVSSGTTALIDGVQPLV FT AGALAGPLLRQYVSRGQWLGLWLGLSGVATVTVADAGAAGAEVAWWAYLVPFLGMLSLV FT AATFLEGRTRVPVAPRVALTIHCATSAVLFSGLALGLGAAAPPAGSSFWLATAWLVVLP FT TFGGYGLYWLILRRSGITEVNTLMFLMAPVTAVWGALMFGEPFGVQTALGLAVGLAAVV FT VVRRGGGARRERPVRSGADRPAAGGPTADQPTNRPTDRPTAAGSTDRPTADRR" FT RBS 46798..46802 FT /note="possible RBS upstream of SC1C2.13" FT CDS 46804..47388 FT /transl_table=11 FT /gene="SCO5532" FT /gene_synonym="SC1C2.13" FT /product="putative transcriptional regulator" FT /note="SC1C2.13, probable transcriptional regulator, len: FT 194 aa; simialr to many e.g. S. lividans TR:G3293540 FT (EMBL:AF072709) putative transcriptional regulator (192 FT aa), fasta scores; opt: 342 z-score: 493.9 E(): 2.9e-20, FT 42.0% identity in 181 aa overlap. Contains Pfam match to FT entry PF00440 tetR, Bacterial regulatory proteins, tetR FT family, score 30.80, E-value 8.3e-07" FT /db_xref="GOA:O86514" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:O86514" FT /protein_id="CAA19980.1" FT /translation="MGPQEKPRRVRMTPGARRVLAAAERLFYEHGIHAVGVDTIAAEAG FT VTKKTLYDRFGSKEQIVVEYLAGRDERWRELLAGRLAAAGEGPAARVVAVFEASRAWSE FT LYGAKGCSMINAHAEISDPGHPAYPVITGQKRWMLDLFTGLARDIDAAGADRLARTLVL FT LHEGALVSHGVGVLPDPFGAALDQVRELLDG" FT misc_feature 46858..46998 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 30.80, E-value FT 8.3e-07" FT CDS complement(47474..48031) FT /transl_table=11 FT /gene="SCO5533" FT /gene_synonym="SC1C2.14c" FT /product="conserved hypothetical protein SC1C2.14c" FT /note="SC1C2.14c, unknown, len: 185 aa; similar to FT hypothetical proteins from E. coli YCEI_ECOLI (191 aa), FT fasta scores; opt: 373 z-score: 567.7 E(): 2.3e-24, 34.1% FT identity in 179 aa overlap and H. pylori TR:O25873 FT (EMBL:AE000633) HP1286 (182 aa), fasta scores; opt: 279 FT z-score: 242.2 E(): 3.1e-06, 27.9% identity in 172 aa FT overlap" FT /db_xref="InterPro:IPR007372" FT /db_xref="UniProtKB/TrEMBL:O86515" FT /protein_id="CAA19981.1" FT /translation="MTTTPDLSTLTGDYTVDPAHTTIGFTARHAMVTNVKGKFLDFTGT FT LHLDGADPSRSTASLDITMDSIDTGSPDRDGHLKSSDFFNTGEYPTMTFRSTKAESLGG FT DDYRITGDLSILGTTKPLTIDLEFNGAAKDPFGNERVGFEGKAEIKRSEWGLTWNAALE FT TGGVLVSDKIKLNFDISAIRQA" FT RBS complement(48037..48041) FT /note="possible RBS upstream of SC1C2.14c" FT CDS 48180..50510 FT /transl_table=11 FT /gene="SCO5534" FT /gene_synonym="SC1C2.15" FT /product="putative secreted lyase" FT /note="SC1C2.15, possible secreted lyase, len: 776 aa; FT similar to hyaluronidase from several organisms e.g. FT Propionibacterium acnes TR:Q59634 (EMBL:U15927) FT hyaluronidase (EC 4.2.2.1) (hyaluronate lyase) (752 aa), FT fasta scores; opt: 407 z-score: 783.6 E(): 0, 31.5% FT identity in 781 aa overlap. Contains N-tertminal signal FT sequence" FT /db_xref="GOA:O86516" FT /db_xref="HSSP:1J0M" FT /db_xref="InterPro:IPR012329" FT /db_xref="UniProtKB/TrEMBL:O86516" FT /protein_id="CAA19982.1" FT /translation="MTPQRPTAPSRRAVLLAAAAAAALTTVPRAAAATADPYDALRRRW FT LGITLGTGYDPAAEPYASRLAETGERAREHRATMAPTPTSLWPGHPFDPPAGITFAYGR FT LWTMTEAYVQEGTGATGDPALLADILRGLDHLSATVYHPATTRYGNWWEWQIGSPRLLM FT DITAALYDHLGADRVAAACAAVDHFVPDAMLGAYTGTSTGANRVDLCRSVALRGVLGRA FT PAKIALARDALSPVFPYVTKGDGLYADGSFVQHTWVAYSGTYGQVMLDGLGRLFTLLAG FT SEWEVTDPGRQLVLDSVEHAYAPLIHDGLVMDTVNGRAISRGYLKSDDLHVMRSDHFHG FT QQLIAAMAVLAGGASNAERERWHARIKGWIERDTVTPVLTAPQFPVADLTRLHAIADAP FT GEAAPEPVGHHLFAAMDRAVHRRPAFTAGLAMASDRIAHYECGNGENPRGWHTGAGMLT FT WWANGTRADQYTDWFWPTVDWYRLPGTTVSTKRLADRAGGEWGAPKPDVRWVGGATDGE FT YAAVGQHLKGLGSTLEARKSWFFLDDAVVCLGAGITCADGVPVETVVDNRNLGEGGTQA FT LVRGRHWAHLEGHGGWIVPGGALRTLREDRTGAWSDINTTSTTERRTRRWQTLWLDHGT FT DPAGADYVYTVMPGASRAALARRAADRHWLTVLANDDRRQAVSVPSLGLTAANFWQAGT FT AGPLTTTAGASVLVRRRGRTATLRVSEPPRTGEALEIVWDHPVGAVLRADETVEILATG FT RRLHLRVTPGVVCTTHECEVTLS" FT CDS 50665..52248 FT /transl_table=11 FT /gene="SCO5535" FT /gene_synonym="SC1C2.16" FT /product="putative carboxyl transferase" FT /note="SC1C2.16, probable carboxyl transferase, len: 527 FT aa; similar to many e.g. Veillonella parvula TR:Q57079 FT (EMBL:Z24754) alpha-subunit, methylmalonyl-coa FT decarboxylase (509 aa), fasta scores; opt: 1929 z-score: FT 2387.4 E(): 0, 55.9% identity in 510 aa overlap and FT Myxococcus xanthus TR:O24789 (EMBL:AB007000) propionyl-coa FT carboxylase (524 aa), fasta scores; opt: 1922 z-score: FT 2359.6 E(): 0, 55.7% identity in 528 aa overlap" FT /db_xref="GOA:O86517" FT /db_xref="HSSP:1ON9" FT /db_xref="InterPro:IPR011762" FT /db_xref="UniProtKB/TrEMBL:O86517" FT /protein_id="CAA19983.1" FT /translation="MTVLDEAPGEPTDARGRVAELHGIRAAALAGPSEKATAAQHAKGK FT LTARERIELLLDPGSFREVEQLRRHRATGFGLEAKKPYTDGVITGWGTVEGRTVFVYAH FT DFRIFGGALGEAHATKIHKIMDMAIAAGAPLVSLNDGAGARIQEGVSALAGYGGIFQRN FT TKASGVIPQISVMLGPCAGGAAYSPALTDFVFMVRDTSQMFITGPDVVKAVTGEEITQN FT GLGGADVHAETSGVCHFAYDDEETCLAEVRYLLSLLPQNNRENPPRAESSDPVDRRSDT FT LLDLVPADGNRPYDMTKVIEELVDEGEYLEVHERWARNIICALARLDGRVVGIVANQPQ FT ALAGVLDIEASEKAARFVQMCDAFNIPIITLLDVPGFLPGVDQEHGGIIRHGAKLLYAY FT CNATVPRISLILRKAYGGAYIVMDSQSIGADLTYAWPTNEIAVMGAEGAANVIFRRQIA FT DAEDPEAMRARMVKEYKSELMHPYYAAERGLVDDVIDPAETREVLITSLAMLHTKHADL FT PSRKHGNPPQ" FT RBS 52253..52257 FT /note="possible RBS upstream of SC1C2.17" FT CDS 52266..52463 FT /transl_table=11 FT /gene="SCO5536" FT /gene_synonym="SC1C2.17" FT /product="hypothetical protein SC1C2.17" FT /note="SC1C2.17, unknown, len: 65 aa" FT /db_xref="UniProtKB/TrEMBL:O86518" FT /protein_id="CAA19984.1" FT /translation="MSPADIRVEKGHAEPEEVAAITALLLARAAARPAEIAPTHGGGRA FT RAGWRRLEREPGFRAPHSWR" FT stem_loop 52472..52509 FT /note="hairpin_loop with 17bp stem" FT CDS complement(52766..53290) FT /transl_table=11 FT /gene="SCO5537" FT /gene_synonym="SC1C2.18c" FT /gene_synonym="cvnD2" FT /product="putative ATP/GTP binding protein" FT /note="SC1C2.18c, cvnD2, probable ATP/GTP binding protein, FT len: 174 aa; similar to prokaryotic hypothetical proteins FT e.g. M. tuberculosis TR:O50391 (EMBL:AL009198) MTV004.19C FT (193 aa), fasta scores; opt: 756 z-score: 1186.3 E(): 0, FT 67.4% identity in 175 aa overlap, and more distantly to the FT yeast GTP-binding protein SEC4_YEAST RAS-related protein FT SEC4 (215 aa), fasta scores; opt: 113 z-score: 244.1 E(): FT 2.4e-06, 24.6% identity in 191 aa overlap. Contains PS00017 FT ATP /GTP-binding site motif A (P-loop). 97.1% identical to FT upstream gene SC1C2.22c" FT /db_xref="GOA:O86519" FT /db_xref="InterPro:IPR004130" FT /db_xref="UniProtKB/TrEMBL:O86519" FT /protein_id="CAA19985.1" FT /translation="MVAGGFGVGKTTFVGAVSEINPLRTEAVMTSASAGIDDLTHTGDK FT TTTTVAMDFGRITLDQDLILYLFGTPGQDRFWFMWDDLVRGAIGAIVLVDTRRLADCFP FT AVDYFENSGLPFVIALNGFDGQQPYNPDEVREALQIGPDTPIITTDARHRADAKSALIT FT LVEHALMARLR" FT misc_feature complement(53258..53281) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(53328..53900) FT /transl_table=11 FT /gene="SCO5538" FT /gene_synonym="SC1C2.19c" FT /gene_synonym="cvnC2" FT /product="conserved hypothetical protein SC1C2.19c" FT /note="SC1C2.19c, cvnC2, unknown, len: 190 aa; N-terminus FT is Pro-rich, C-terminus has similarity to M. tuberculosis FT hypothetical protein TR:O50392 (EMBL:AL009198) MTV004.20C FT (122 aa), fasta scores; opt: 231 z-score: 217.7 E(): FT 7.1e-05, 41.0% identity in 122 aa overlap. C-terminus is FT 84.7% identical to upstream gene SC3A9.23c" FT /db_xref="InterPro:IPR007995" FT /db_xref="UniProtKB/TrEMBL:O86520" FT /protein_id="CAA19986.1" FT /translation="MGTPPGGPSSGNWSYGPGQGQGDGSANGYGYPSVPNHRQPYAPQG FT PGPSPYDQPHAPRIQPVQPQRRTPEPAPAGASNNPLVRPYAMTGGRTRPRYQLAIEALV FT HTTAQPHQMQGQLPEHQRICNLCREIKSVAEISALLTIPLGVARILVADLAEAGLVAIH FT QPGGDESAGGQPDVTLLERVLSGLRKL" FT RBS complement(53906..53911) FT /note="possible RBS upstream of SC1C2.19c" FT CDS complement(53995..54417) FT /transl_table=11 FT /gene="SCO5539" FT /gene_synonym="SC1C2.20c" FT /gene_synonym="cvnB2" FT /product="conserved hypothetical protein SC1C2.20c" FT /note="SC1C2.20c, cvnB2, unknown, len: 140 aa; similar to FT M. tuberculosis hypothetical protein TR:O50393 FT (EMBL:AL009198) MTV004.21c (130 aa), fasta scores; opt: FT 445 z-score: 754.7 E(): 0, 56.9% identity in 116 aa FT overlap. 94.2% identical to upstream gene SC1C2.24c" FT /db_xref="InterPro:IPR004942" FT /db_xref="UniProtKB/TrEMBL:O86521" FT /protein_id="CAA19987.1" FT /translation="MSPMSQAAQNLNWLITNFVDNTPGVSHTVVVSADGLLLAMSEGFP FT RDRADQLAAVASGLTSLTAGASRIFEGGSVNQTVVEMERGFLFIMSISDGSSLAVLAHP FT EADIGLIGYEMALLVDRAGTVLTPDLRAELQGSLLN" FT CDS complement(54419..57754) FT /transl_table=11 FT /gene="SCO5540" FT /gene_synonym="SC1C2.21c" FT /gene_synonym="cvnA2" FT /product="putative membrane protein SC1C2.21c" FT /note="SC1C2.21c, cvnA2, unknown, len: 1111 aa; contains FT two possible transmembrane domains at around 100 and 400 FT aa, a Gln-rich region at around 850 aa and a probable FT coiled-coil domain from 297 to 327. Overall 35.6% identical FT to upstream gene SC1C2.25c, but with much higher similarity FT between aa 477 and 719" FT /db_xref="GOA:O86522" FT /db_xref="InterPro:IPR003660" FT /db_xref="UniProtKB/TrEMBL:O86522" FT /protein_id="CAA19988.1" FT /translation="MTDGVGSETQRHDTGADRREVVGRVRRSKNSPEPSARGNFTPPPR FT TAAPAPAPAAEPQAEPPAPSGGRFTPRNWRVTTRLNAILLIPVLVGLVMGGFQVKGSID FT TWQDAEDAESTARLVRASLGYANALYNERDITAAPLLQGKGEKDTTVAAARRATDEAAD FT TFDAAAQGMPGKAGLERRLKVFREQEPKLQTLRAAAYTSKLKGVETEEGYTGVAHPLME FT FANELGLGTGNITSYGRTVYAISLTKAALSLERSIGMHMLVKPGPEPGHLASQRVALSS FT YAYLERIAIEEYIGGGTEADAQKLEDAQAELKEDGAAMAKEAKAKDPDYVPPPSNPTTM FT ISELAGLESTDTSDRAELAQQGITPENWWAVNTLKFDAYQKIESDLADKAVSEASTIAD FT DAERDAYITGAAVVIALLAAFVLAGMVARGMSRSMRRLRNAAFGIAEQRLPMLVDQLSR FT TDPGRVDTRVQPIPITSTDEIGEVARAFDQVHREAVRLAAEQALLRGNINAIFTNLSRR FT NQSLIEGQLSLITDLENNEADPDQLENLFRLDHLATRMRRNGENLLVLAGEEPGRRWDQ FT PVPLVDVLRAASSEVEQYERIELSGVPEAEIHGRAVTDLVHLLAELLENATTFSSPQTK FT VRVTATRLPDGRVMVEIHDKGIGLTAEDFADINHKLANPPTVDAAISQRMGLFVVGRLS FT DRHGIRVQLRPSGEQAGTTSLVMLPDAITHGGGGEHQQQRDDFTVSQIIPEQNFQGGGE FT SFGQVGQPMRTAAELGFDDSRYAEIPDDIRELDPVGRSLMREERRAALEAQSHPELPGP FT ADRGGAGNDGATGFQDQFAGQQPGYDGQQPGYDGQQPGYDQSPDGYQQQPNGAYQESPN FT AAYDQQSAYADPQQAYQEPRQASYDEQYYAPNGGLPESGNYSPFDQRRHQDDWPQQDGY FT QNGYPDQYPTGAPQSQSAEAADVSEADRVGFDRPGPAPSAAHELTDAGLPRRGSTASGA FT GDAGHVGQETPAAAPGAGGEDTWRSANDDRWQQASSLRKPKAGGVTSSGLPRRVPKANL FT VEGAAETTPQGGPQVSRAPEDVRGRLSNLRRGVERGRNAGSETNGQDTRNEHRGPDSTY FT NQER" FT RBS complement(54425..54429) FT /note="possible RBS upstream of SC1C2.20c" FT CDS complement(58089..58613) FT /transl_table=11 FT /gene="SCO5541" FT /gene_synonym="SC1C2.22c" FT /gene_synonym="cvnD1" FT /product="putative ATP-GTP binding protein" FT /note="SC1C2.22c, cvnD1, probable ATP /GTP binding protein, FT len: 174 aa; similar to prokaryotic hypothetical proteins FT e.g. M. tuberculosis TR:O50391 (EMBL:AL009198) MTV004.19C FT (193 aa), fasta scores; opt: 718 z-score: 1252.2 E(): 0, FT 64.9% identity in 168 aa overlap, and more distantly to the FT yeast GTP-binding protein SEC4_YEAST RAS-related protein FT SEC4 (215 aa), fasta scores; opt: 111 z-score: 192.5 E(): FT 0.0018, 25.0% identity in 128 aa overlap. Contains PS00017 FT ATP /GTP-binding site motif A (P-loop). 97.1% identitical FT to downstream gene SC1C2.18c" FT /db_xref="GOA:Q9R7V6" FT /db_xref="InterPro:IPR004130" FT /db_xref="UniProtKB/TrEMBL:Q9R7V6" FT /protein_id="CAA19989.1" FT /translation="MVAGGFGVGKTTFVGAVSEINPLRTEAVMTSASAGIDDLTHAGDK FT TTTTVAMDFGRITLDQDLILYLFGTPGQDRFWFMWDDLVRGAIGAVVLCDTRRLADCFP FT AVDYFENSGLPFVVALNGFDGQQPYSPDEVREALQIGPDTPIITTDARHRADAKSALIT FT LVEHALMARLR" FT misc_feature complement(58581..58604) FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT CDS complement(58645..59043) FT /transl_table=11 FT /gene="SCO5542" FT /gene_synonym="SC1C2.23c" FT /gene_synonym="cvnC1" FT /product="hypothetical protein SC1C2.23c" FT /note="SC1C2.23c, cvnC1, unknown, len: 132 aa; similar to FT M. tuberculosis hypothetical protein TR:O50392 FT (EMBL:AL009198) MTV004.20C (122 aa), fasta scores; opt: 236 FT z-score: 328.3 E(): 4.9e-11, 38.5% identity in 122 aa FT overlap. C-terminus is 84.7% identical to downstream gene FT SC1C2.19c" FT /db_xref="InterPro:IPR007995" FT /db_xref="UniProtKB/TrEMBL:O86523" FT /protein_id="CAA19990.1" FT /translation="MTPPTASHDPYAEPYEDEGDQPLVRPYAMTGGRTRPRYQLAIEAL FT ISTTADPAALMGLLPEHQRICHLCREVKSVAEVSALLAMPLGVARILVADLAEAGLVAI FT HQPGGDENNGGAPDVTLLERVLSGLRKL" FT CDS complement(59155..59568) FT /transl_table=11 FT /gene="SCO5543" FT /gene_synonym="SC1C2.24c" FT /gene_synonym="cvnB1" FT /product="conserved hypothetical protein SC1C2.24c" FT /note="SC1C2.24c, cvnB1, unknown, len: 137 aa; M. FT tuberculosis hypothetical protein TR:O50393 (EMBL:AL009198) FT MTV004.21c (130 aa), fasta scores; opt: 466 z-score: 804.8 FT E(): 0, 58.6% identity in 116 aa overlap. 94.2% identical FT to downstream gene SC1C2.20c" FT /db_xref="InterPro:IPR004942" FT /db_xref="UniProtKB/TrEMBL:O86524" FT /protein_id="CAA19991.1" FT /translation="MSQAAQNLNWLITNFVDNTPGVSHTVVVSADGLLLAMSEGFPRDR FT ADQLAAVASGLTSLTAGASRIFEGGNVAQTVVEMERGFLFLMSVSDGSSLAVLAHPECD FT IGLVGYEMALLVDRAGAVLTPDLRAELQGSLLH" FT CDS complement(59578..63567) FT /transl_table=11 FT /gene="SCO5544" FT /gene_synonym="SC1C2.25c" FT /gene_synonym="cvnA1" FT /product="putative membrane protein SC1C2.25c" FT /note="SC1C2.25c, cvnA1, unknown, len: 1329 aa; contains FT two possible transmembrane domains at around 100 and 400 FT aa, and probable coiled-coil domains from 112 to 144 and FT 360 to 398. Overall 35.6% identical to downstream gene FT SC1C2.22c, but with much higher similarity between aa 468 FT and 709" FT /db_xref="GOA:O86525" FT /db_xref="InterPro:IPR003660" FT /db_xref="UniProtKB/TrEMBL:O86525" FT /protein_id="CAA19992.1" FT /translation="MQGRFKRDGSASAEPEPQGGTGPKAVSSSPQHAQNPGQTQPGDSG FT ERAGQAAGPSAPGQQSPAKPAKGSTGPGPRIALRNWRISTRLVSLLALPVVAATSLGAL FT RINQSMDDIQQLENMKLLTEMTKQATELAAALQEERDQSAGPLAHGSKSSAIAVKGDRE FT QTDRALKNFLDKSEQIDAASKDGKLVGVRDSLVGIASDLNDLTKIRSTAYTATDNSTQT FT VEAYHRLITHLLDLSQDMAEATSNPDMIQRTRALSAFSSAKEYASIQRAVLAAALPANN FT TDKGDLAENDRLYAQSALQSQTSEIRSFTSIYGDGAEDLLKPISEGNPVIEASDQYAGR FT AVGKKDGLASLKARSYQDWLDDSSTKIQQMKNIELKLLEDMEQQARELRNESEQEAIIS FT GVLILLVLGVSLVGAFVVARSMIRSLRRLEDTATKVAQDRLPELVKQLSETDPQDVDTS FT VESVGVHSRDEIGRVAAAFDDVHREAVRLAAEQALLRGNVNAMFTNLSRRSQGLIQRQL FT SLISELESREADPDQLSSLFKLDHLATRMRRNGENLLVLAGEEPGRRWTRPVPLVDVLR FT AAASEVEQYERIELASVPSTEVAGRVVNDLVHLLAELLENATSFSSPQTKVKVTGHALP FT DGRVLIEIHDTGIGLSPEDLAAINERLASPPTVDVSVSRRMGLFVVGRLSQRHGIRIQL FT RPSDSGGTTALVMLPVDVAQGGRKPQPKPGQPGAGNGGPAAAQAAAGVAAARRGGQGGG FT ALAGGGAFGGGSGGGALGAGAPGGRLGAGQGPRAALPGRDAGGRPGAPGGARGPQSPAV FT PGQQNRPAPAGAGAGAGQQAPGAPQGLQAAGMNAPQGNAPANNASQGQDMFGGNRAPGA FT PPQRKRGGNGDAEQGRRPQLPPRGGPRAELPGGNPQPRVPSWSDENAQPPVPRASLDAP FT RGHDEPDSSRTDRTPRLDERQGPGSTAEMPAVPRFGEPQSPAATAEFARPDFDAPAPRR FT DESQDTGQYAQPGQNQYDARNEYEDQYGQQSQYGQDQYGQDQYAPGQYGQAGPGQDQYD FT RPRFGQDAPQNDQFARPEPAAPQQDGGAFVRSDVFGGQPAPNGQAPADRFAASQGYDNG FT STGQHGLPGRQDPAVTGQFERPQAGGTQGGNDFGAPRPPAPQRPVPQEPAGQNTNGTPA FT QRPGDGWALPPASGPGDGRTPLYDTLETNWFHGDRESRAPQAAPAASPEPQAAQPQTPA FT APQRPATSAWRSSPNDDLVRQAERVRQPAAGGVTTSGLPRRVPRANLVPGTAQQQSHQS FT GPAVSRAPDDVRGRLTNLRRGIAQGRQAGTNQTGSYPRPTHQQER" FT RBS complement(63579..63582) FT /note="possible RBS upstream of SC1C2.25c" FT CDS 64182..64358 FT /transl_table=11 FT /gene="SCO5545" FT /gene_synonym="SC1C2.26" FT /product="hypothetical protein SC1C2.26" FT /note="SC1C2.26, unknown, len: 58 aa" FT /db_xref="UniProtKB/TrEMBL:O86526" FT /protein_id="CAA19993.1" FT /translation="MMFHKIANPRRTTLAHLQDADELRTPEQPEHAVELPAQTANPRRT FT ILMEAPVTASVAE" FT CDS 64485..65270 FT /transl_table=11 FT /gene="SCO5546" FT /gene_synonym="SC1C2.27" FT /product="conserved hypothetical protein SC1C2.27" FT /note="SC1C2.27, unknown, len: 261 aa; similar to FT hypothetical proteins e.g. E. coli TR:P76004 FT (EMBL:AE000216) O219 (219 aa), fasta scores; opt: 555 FT z-score: 764.8 E(): 0, 45.7% identity in 208 aa overlap and FT to e.g. HPCE_ECOLI 2-hydroxyhepta-2,4-diene-1,7-dioate FT isomerase (405 aa), fasta scores; opt: 389 z-score: 507.2 FT E(): 5.3e-21, 33.9% identity in 218 aa overlap" FT /db_xref="GOA:O86527" FT /db_xref="HSSP:1GTT" FT /db_xref="InterPro:IPR002529" FT /db_xref="UniProtKB/TrEMBL:O86527" FT /protein_id="CAA19994.1" FT /translation="MRIARFSIDGNVAFGAVEGDQPDQLVLDIIKGIPFADYELSGTKV FT PLSKVRLLPPVLPSKVVAFGRNYAEHARELGNEVPDAPFAFFKPSTSVIGPGDAVQYPS FT FTEELHHEAELAVVIGRMCREVPRERVQDVIFGYTCANDITARDVQRREKQWARAKGFD FT SSCPLGPWVETDLDLAAAGDLTVQLTVNGAQRQLGRTSEMIHSIEDLIVNISEAMTLLP FT GDVILTGTPAGVGPLNVGDEVAVTIEGIGTLTNKVVKRG" FT CDS 65263..66747 FT /transl_table=11 FT /gene="SCO5547" FT /gene_synonym="gltX" FT /product="glutamyl-tRNA synthetase" FT /note="SC1C2.28, gltX, glutamyl-tRNA synthetase, len: 494 FT aa; highly similar to many e.g. SYE_ECOLI glutamyl-tRNA FT synthetase (EC 6.1.1.17) (471 aa), fasta scores; opt: 453 FT z-score: 894.0 E(): 0, 37.1% identity in 493 aa overlap. FT Contains Pfam match to entry PF00749 tRNA-synt_1c, tRNA FT synthetases class I (E and Q), score 470.50, E-value FT 1.3e-137" FT /db_xref="GOA:O86528" FT /db_xref="HSSP:1J09" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/Swiss-Prot:O86528" FT /protein_id="CAA19995.1" FT /translation="MASASGSPVRVRFCPSPTGNPHVGLVRTALFNWAFARHHQGTLVF FT RIEDTDAARDSEESYDQLLDSMRWLGFDWDEGPEVGGPHAPYRQSQRMDIYQDVAQKLL FT DAGHAYRCYCSQEELDTRREAARAAGKPSGYDGHCRELTDAQVEEYTSQGREPIVRFRM FT PDEAITFTDLVRGEITYLPENVPDYGIVRANGAPLYTLVNPVDDALMEITHVLRGEDLL FT SSTPRQIALYKALIELGVAKEIPAFGHLPYVMGEGNKKLSKRDPQSSLNLYRERGFLPE FT GLLNYLSLLGWSLSADQDIFTIEEMVAAFDVSDVQPNPARFDLKKCEAINGDHIRLLEV FT KDFTERCRPWLKAPVAPWAPEDFDEAKWQAIAPHAQTRLKVLSEITDNVDFLFLPEPVF FT DEASWTKAMKEGSDALLTTAREKLDAADWTSPEALKEAVLAAGEAHGLKLGKAQAPVRV FT AVTGRTVGLPLFESLEVLGKEKALARIDAALARLAA" FT misc_feature 65284..66729 FT /note="Pfam match to entry PF00749 tRNA-synt_1c, tRNA FT synthetases class I (E and Q), score 470.50, E-value FT 1.3e-137" FT CDS 66855..67250 FT /transl_table=11 FT /gene="SCO5548" FT /gene_synonym="SC1C2.29" FT /product="hypothetical protein SC1C2.29" FT /note="SC1C2.29, unknown, len: 131 aa; similar to M. FT tuberculosis hypothetical protein TR:O07205 (EMBL:Z96072) FT MTCY05A6.25 (142 aa), fasta scores; opt: 149 z-score: 314.1 FT E(): 3e-10, 34.7% identity in 121 aa overlap" FT /db_xref="InterPro:IPR006175" FT /db_xref="UniProtKB/TrEMBL:O86529" FT /protein_id="CAA19996.1" FT /translation="MRREDIDPRFFGDRLAYNRAVLVEQPRRWLVVAGHEARDDEGGIA FT AVDDVRGQLRLTFRRLAETLDKAGFALSDLVQIRIFTVDIEAVTAHYDAVLDELAAADC FT RPASLLAEVRALSDPRMLVEIEGLAAQ" FT CDS 67321..68055 FT /transl_table=11 FT /gene="SCO5549" FT /gene_synonym="SC1C2.30" FT /product="putative hydrolase" FT /note="SC1C2.30, probable hydrolase, len: 244 aa; similar FT to hypothetical proteins from many organisms and to FT HAD1_PSESP 2-haloalkanoic acid dehalogenase I (EC 3.8. (227 FT aa), fasta scores; opt: 201 z-score: 261.1 E(): 2.7e-07, FT 30.4% identity in 237 aa overlap. Contains Pfam match to FT entry PF00702 Hydrolase, haloacid dehalogenase-like FT hydrolase, score 43.50, E-value 4.8e-09" FT /db_xref="GOA:O86530" FT /db_xref="InterPro:IPR005833" FT /db_xref="UniProtKB/TrEMBL:O86530" FT /protein_id="CAA19997.1" FT /translation="MPIKAVVWDVDDTLFDYTTADREGMRAHLVAEGLLAGYGSAEEAL FT VRWREITEQQWARFSAGEVDFVTQRRDRTRVFLGRPELTDAEADDWFQRYVTHYEAAWS FT LFPDVMPVLDALAGSHRHAVLSNSSLTVQDRKLRVLGVHDRFEAILCAAELGVSKPEAG FT AFLAACDALALGPAEVAYVGDHPEIDGRGAADAGLLSVWIDRGGAYATVDPPAGPRRIA FT SLSELPALLGADTRFGAPSTFG" FT misc_feature 67327..67938 FT /note="Pfam match to entry PF00702 Hydrolase, haloacid FT dehalogenase-like hydrolase, score 43.50, E-value 4.8e-09" FT tRNA 68148..68219 FT /note="tRNA Gln anticodon CTG, Cove score 58.49" FT tRNA 68259..68331 FT /note="tRNA Glu anticodon CTC, Cove score 63.89" FT tRNA 68394..68469 FT /note="tRNA Glu anticodon CTC, Cove score 64.51" FT tRNA 68487..68558 FT /note="tRNA Gln anticodon CTG, Cove score 57.02" FT tRNA 68603..68675 FT /note="tRNA Glu anticodon CTC, Cove score 63.89" FT CDS complement(68735..69379) FT /transl_table=11 FT /gene="SCO5550" FT /gene_synonym="SC1C2.31c" FT /product="putative transcriptional regulator" FT /note="SC1C2.31c, probable transcriptional regulator, len: FT 214 aa; N-terminus is similar to the N-terminus of members FT of the MerR family, e.g. MERR_THIFE mercuric resistance FT operon regulatory protein (122 aa), fasta scores; opt: 111 FT z-score: 189.7 E(): 0.0026, 30.3% identity in 66 aa FT overlap. Contains probable helix-turn-helix motif at aa FT 2-23 (1799, +5.31 SD)" FT /db_xref="GOA:O86531" FT /db_xref="InterPro:IPR000551" FT /db_xref="PDB:2DG6" FT /db_xref="UniProtKB/TrEMBL:O86531" FT /protein_id="CAA19998.1" FT /translation="MRLADLSKRSGVSTATIKYYLREGLLPPGRQVNATTAEYDEDHLR FT RLRLVRALIQVGKVPVATAREVLGHVDDDSLGRTVRLGAALWALPQDAEPDEADPAVAA FT ARVEVDRLLELLGWETSRELAPLSPVHRSLVVAVAALRRLDYPWDAELMAPYGELMMEV FT ARRDLDFMETHASEAEKVEMAVAAAVLFQPVLRALHRLAQEEESARRYGIE" FT RBS complement(69393..69396) FT /note="possible RBS upstream of SC1C2.31c" FT CDS 69461..70033 FT /transl_table=11 FT /gene="SCO5551" FT /gene_synonym="SC1C2.32" FT /product="hypothetical protein SC1C2.32" FT /note="SC1C2.32, unknown, len: 190 aa" FT /db_xref="UniProtKB/TrEMBL:O86532" FT /protein_id="CAA19999.1" FT /translation="MPGTNATAIRTTAAVEGDVTVLLIGMRINHFWAVHHWLPVFLAMP FT RMLRELAKDPKRGLLNHVLLTASPRTYYVVQYWESKEKLYEYAHSPDMFHHRAWAVINR FT KERKGQVRGHVGLWHEAYVVPEGSYESIYADMPPFGLAAAHGQVPLERRGKRARDRFAY FT RTRKTAGAAEARTEKHVVAPGNAPDEG" FT CDS complement(70099..70815) FT /transl_table=11 FT /gene="SCO5552" FT /gene_synonym="SC1C2.33c" FT /product="putative regulator" FT /note="SC1C2.33c, probable regulator, len: 238 aa; similar FT to many e.g. GYLR_STRGR glycerol operon regulatory protein FT (254 aa), fasta scores; opt: 146 z-score: 237.0 E(): FT 5.9e-06, 28.9% identity in 246 aa overlap" FT /db_xref="GOA:O86533" FT /db_xref="InterPro:IPR005471" FT /db_xref="UniProtKB/TrEMBL:O86533" FT /protein_id="CAA20000.1" FT /translation="MDNSSGVGVLDKAALVLSALESGPATLAGLVGATGLARPTAHRLA FT VALEHHRMVARDMQGRFILGPRLAELAAAAGEDRLLATAGPVLTHLRDVTGESAQLYRR FT QGDMRICVAAAERLSGLRDTVPVGSTLTMKAGSSAQILMAWEEPERLHRGLQGARFTAT FT ALSGVRRRGWAQSIGEREPGVASVSAPVRGPSNRVVAAVSVSGPIERLTRHPGRMHAQA FT IIDAAGRLSEALRRNG" FT RBS complement(70825..70828) FT /note="possible RBS upstream of SC1C2.33c" FT CDS 71013..72443 FT /transl_table=11 FT /gene="SCO5553" FT /gene_synonym="leuC" FT /product="3-isopropylmalate dehydratase large subunit" FT /note="SC1C2.34, leuC, 3-isopropylmalate dehydratase large FT subunit, len: 476 aa; highly similar to many e.g. FT LEU2_ECOLI 3-isopropylmalate dehydratase large subunit (465 FT aa), fasta scores; opt: 1943 z-score: 2277.9 E(): 0, 63.3% FT identity in 458 aa overlap. Contains PS00450 and PS01244 FT Aconitase family signatures 1 and 2 and Pfam match to entry FT PF00330 aconitase, Aconitase family (aconitate hydratase), FT score 760.00, E-value 6.9e-232" FT /db_xref="GOA:O86534" FT /db_xref="InterPro:IPR015936" FT /db_xref="UniProtKB/Swiss-Prot:O86534" FT /protein_id="CAA20001.1" FT /translation="MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLR FT KSGRPVRRLDLTIATEDHNTPTLDIDKPIADPVSRAQLETLRKNCADFGVRLHPLGDVE FT QGVVHVVGPQLGLTQPGTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARP FT KTMAITVDGELPEGVTAKDLILAIIARIGTGGGQGYILEYRGEAIEKLSMEARMTICNM FT SIEAGARAGMIAPDETTFAYLQGRPHAPEGADWDAAVEYWKTLRTDDDAEFDAEVVIEA FT AELAPFVTWGTNPGQGAPLSAAVPDPASYEDASERFAAEKALEYMGLEAGQPLRSIQVD FT TVFVGSCTNGRIEDLRAAAEIVRDRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAG FT AEWRHAGCSMCLGMNPDQLAPGERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGH FT LASPADLSAADVPTPAGV" FT misc_feature 71022..72383 FT /note="Pfam match to entry PF00330 aconitase, Aconitase FT family (aconitate hydratase), score 760.00, E-value FT 6.9e-232" FT misc_feature 72027..72077 FT /note="PS00450 Aconitase family signature 1" FT misc_feature 72207..72248 FT /note="PS01244 Aconitase family signature 2" FT misc_feature 72449..72934 FT /note="Pfam match to entry PF00694 Aconitase_C, Aconitase FT C-terminal domain, score 149.00, E-value 8.4e-41" FT CDS 72449..73042 FT /transl_table=11 FT /gene="SCO5554" FT /gene_synonym="leuD" FT /product="3-isopropylmalate dehydratase small subunit" FT /note="SC1C2.35, leuD, 3-isopropylmalate dehydratase small FT subunit, len: 197 aa; highly similar to many e.g. FT LEUD_ECOLI 3-isopropylmalate dehydratase small subunit (201 FT aa), fasta scores; opt: 628 z-score: 1023.1 E(): 0, 52.3% FT identity in 197 aa overlap. Contains Pfam match to entry FT PF00694 Aconitase_C, Aconitase C-terminal domain, score FT 149.00, E-value 8.4e-41" FT /db_xref="GOA:O86535" FT /db_xref="InterPro:IPR000573" FT /db_xref="UniProtKB/Swiss-Prot:O86535" FT /protein_id="CAA20002.1" FT /translation="MEAFTKHTGRAVPLRRSNVDTDQIIPAHWLKKVTRDGFEDGLFEA FT WRKDPEFVLNRPEREGATVLVAGPDFGTGSSREHAVWALQNYGFKTVVSSRFADIFRGN FT SLKNGLLTVVLDQKTVDALWELVERDPQAEITVDLEAREVRAEGVTASFELDENSRWRL FT LNGLDDISITLQNEADIAAYEAKRPSFKPQTVQV" FT stem_loop 73109..73143 FT /note="hairpin_loop with 17bp stem" FT CDS 73328..73558 FT /transl_table=11 FT /gene="SCO5555" FT /gene_synonym="SC1C2.36" FT /product="hypothetical protein SC1C2.36" FT /note="SC1C2.36, unknown, len: 76 aa" FT /db_xref="UniProtKB/TrEMBL:O86536" FT /protein_id="CAA20003.1" FT /translation="MEHDGQLELYTAVASRLKEAHTRVRALQVPEGVRMALTRKLLVIT FT AAAKHDLAGAARRLDRFTDDLDAGRIPEEEG" FT misc_feature 73696..73962 FT /note="Pfam match to entry PF00216 Bac_DNA_binding, FT Bacterial DNA-binding proteins, score 104.40, E-value FT 9.2e-29" FT CDS 73696..74352 FT /transl_table=11 FT /gene="SCO5556" FT /gene_synonym="SC1C2.37" FT /product="histone-like DNA binding protein" FT /note="SC1C2.37, histone-like DNA binding protein, len: 218 FT aa; N-terminus is highly simialar to many bacterial HU FT proteins e.g. DBHB_ECOLI DNA-binding protein HU-beta (NS1) FT (HU-1) (90 aa), fasta scores; opt: 230 z-score: 300.3 E(): FT 1.8e-09, 40.0% identity in 90 aa overlap, and contains FT PS00045 Bacterial histone-like DNA-binding proteins FT signature and Pfam match to entry PF00216 Bac_DNA_binding, FT Bacterial DNA-binding proteins, score 104.40, E-value FT 9.2e-29. C-terminus contains 18 degenerate repeats of an (A FT /T)(3-5)KK motif. A similar C-terminal extension is also FT present in the M. tuberculosis homologue TR:P95109 FT (EMBL:Z83018) dna-binding protein MTCY349.01 (214 aa), FT fasta scores; opt: 563 z-score: 543.5 E(): 5e-23, 50.9% FT identity in 220 aa overlap, and to a lesser extent in the FT M. leprae homologue. The repeats are simlar to those in FT hrdB (SC5B8.10, 45.4% identity in 97 aa overlap)" FT /db_xref="GOA:P0A3H7" FT /db_xref="HSSP:1HUE" FT /db_xref="InterPro:IPR000119" FT /db_xref="UniProtKB/Swiss-Prot:P0A3H7" FT /protein_id="CAA20004.1" FT /translation="MNKAQLVEAIADKLGGRQQAADAVDAVLDALVRAVVAGDRVSVTG FT FGSFEKVDRPARYARNPQTGERVRVKKTSVPRFRAGQGFKDLVSGSKKLPKNDIAVKKA FT PKGSLSGPPPTISKAAGKKAAAKKATGAAKKTTGAAKKTSAAAKKTTAKKTTGAAKTTA FT KKTTAKKSAAKTTTAAAKKTAAKKAPAKKATAKKAPAKKSTARKTTAKKATARKK" FT misc_feature 73828..73887 FT /note="PS00045 Bacterial histone-like DNA-binding proteins FT signature" FT repeat_region 74047..74347 FT /note="degenerate 15bp repeats" FT CDS complement(74467..74700) FT /transl_table=11 FT /gene="SCO5557" FT /gene_synonym="SC1C2.38c" FT /product="hypothetical protein SC1C2.38c" FT /note="SC1C2.38c, unknown, len: 77 aa" FT /db_xref="UniProtKB/TrEMBL:O86538" FT /protein_id="CAA20005.1" FT /translation="MQATAYTYDPESRSGQVLLDDGTPVPFDAAAFDAGGLRLLRPGQR FT VRIETEETGAGPGAGGDSGAGRRITLVTLHTF" FT misc_feature 74614..74725 FT /note="Overlap with Streptomyces coelicolor cosmid 1C2 FT (EMBL:AL031124)." FT CDS complement(74710..75348) FT /transl_table=11 FT /gene="SCO5557a" FT /gene_synonym="SC7A1.01c" FT /product="hypothetical protein SC7A1.01c" FT /note="SC7A1.01c, unknown, len: 212 aa; similar to FT TR:P95112 (EMBL:Z83018) hypothetical protein from FT Mycobacterium tuberculosis (214 aa) fasta scores; opt: 420, FT z-score: 422.3, E(): 3.1e-16, (43.5% identity in 207 aa FT overlap) and TR:O33128 (EMBL:Z99263) hypothetical protein FT from Mycobacterium leprae (216 aa) fasta scores; opt: 386, FT z-score: 414.0, E(): 9.1e-16, (40.6% identity in 207 aa FT overlap)." FT /db_xref="InterPro:IPR002835" FT /db_xref="UniProtKB/TrEMBL:Q9ZBS2" FT /protein_id="CAA22400.1" FT /translation="MQWTLVVPVKALARAKSRLSDTADDGLRPGLALAFAQDTVAAALA FT CPAVADVAVVTDDARAGRELAALGAGVVADEPGGGLNAALAHGAAVVRAARPESPVAAL FT NADLPALRPAELARVLAAATQFPRAFLPDAAGIGTTLLTVAPGQELAPAFGADSRARHR FT ASGAVELRLDAVDSVRQDVDTGGDLRSALALGVGPRTAAVAARLLIAGQ" FT CDS 75492..76286 FT /transl_table=11 FT /gene="SCO5558" FT /gene_synonym="SC7A1.02" FT /product="putative acyltransferase" FT /note="SC7A1.02, possible acyltransferase, len: 264aa; FT similar to several proposed acyltransferases eg. TR:O07809 FT (EMBL:Z97188) acyltransferase from Mycobacterium FT tuberculosis (251 aa) fasta scores; opt: 266, z-score: FT 384.5, E(): 4e-14, (29.7% identity in 229 aa overlap)." FT /db_xref="GOA:Q9ZBS1" FT /db_xref="InterPro:IPR002123" FT /db_xref="UniProtKB/TrEMBL:Q9ZBS1" FT /protein_id="CAA22401.1" FT /translation="MPRRRIGFWYRLAAVICKPPLVVLIKRDWRGMENIPAEGGFITAV FT NHNSHVDPFAYAHYQYNTGRVPRFLAKSGLFKKGFVGAAMRGTGQIPVYRESTDALSAF FT RAAIDAVERGECVAFYPEGTLTRDPDGWPMTAKTGAARVALQTKCPVIPVAQWGCNELL FT PPYAKKPSVLPRKTHQVLAGPPVDLSRFYDREMTTEVLKEATEVIMAAVTRQLEEIRGE FT KAPETPYDPRRERIEQRRRTQQAKSQVAPPRTHGPQAEGQST" FT misc_feature 76283..77260 FT /note="Pfam match to entry PF01210 NAD_Gly3P_dh, FT NAD-dependent glycerol-3-phosphate dehydrogenase , score FT 295.10, E-value 8.8e-85" FT CDS 76283..77293 FT /transl_table=11 FT /gene="SCO5559" FT /gene_synonym="SC7A1.03" FT /gene_synonym="gpsA" FT /product="glycerol-3-phosphate dehydrogenase" FT /note="SC7A1.03, gpsA, glycerol-3-phosphate dehydrogenase, FT len: 366aa; similar to many eg. SW:GPDA_BACSU FT glycerol-3-phosphate dehydrogenase from Bacillus subtilis FT (345 aa) fasta scores; opt: 874, z-score: 1221.4, E(): 0, FT (41.8% identity in 330 aa overlap). Contains a possible FT PS00017 ATP /GTP-binding site motif A (P-loop) and Pfam FT match to entry PF01210 NAD_Gly3P_dh, NAD-dependent FT glycerol-3-phosphate dehydrogenase, score 295.10, E-value FT 8.8e-85." FT /db_xref="GOA:Q9ZBS0" FT /db_xref="HSSP:1EVY" FT /db_xref="InterPro:IPR006109" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZBS0" FT /protein_id="CAA22402.1" FT /translation="MSKPVKAAVFGTGSWGTAFGTVLADAGCEVTLWGRRAALADAVNS FT TRTNPDYLPGVELPENLRATTDAAEAARDADFTVLAVPSQTLRAGLADWTPLLAPGTVL FT VSLMKGVELGSAMRMSEVIGDVAKVGAERIAVVTGPNLAREIAARMPAAAVVACPDETV FT AQRLQAACHTPYFRPYTNTDVVGCELGGAVKNVIGLAVGIADGMGLGDNAKGSLITRGL FT AETTRLGVALGADPLTFSGLAGLGDLVATCSSPLSRNHTFGTNLGKGMTLEETNAVTKQ FT TAEGVKSCESVLDLARRHGVDMPITETVVAIVHEGKSPVVAVKELMSRSAKPERR" FT misc_feature 77213..77236 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)." FT CDS 77385..78554 FT /transl_table=11 FT /gene="SCO5560" FT /gene_synonym="SC7A1.04" FT /product="D-alanine-D-alanine ligase" FT /note="SC7A1.04, ddlA, D-alanine-D-alanine ligase, len: 389 FT aa; similar to many eg. SW:DDLA_SALTY D-alanine-D-alanine FT ligase from Salmonella typhimurium (363 aa) fasta scores; FT opt: 742, z-score: 1018.5, E(): 0, (39.3% identity in 377 FT aa overlap). Contains PS00843 D-alanine--D-alanine ligase FT signature 1." FT /db_xref="GOA:Q9ZBR9" FT /db_xref="HSSP:1E4E" FT /db_xref="InterPro:IPR013817" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZBR9" FT /protein_id="CAA22403.1" FT /translation="MSTENLPQNPEQSPRRPPRKPRVAVVFGGRSSEHGISVVTAGAVL FT AAIDRTRYDVLPIGITRDGRWALTADEPERMAITERRTPDVEELAESTEGGVLLPVDPA FT NREVVYSEPGSVPKALGEVDVVFPVLHGPYGEDGTLQGLLELSGVPYVGAGVLASAVGQ FT DKEYMKAVFTSYGLKVGPYAVIRPREWEQDRSGARKKIVDFAGEHGWPLFVKPARAGSS FT IGITKVDDLAGLDEAIEEARRHDPKILVEAALRGREIECGVLEFEDGPRASVPAEIPPP FT SEHAYYDFEAKYIDSTPGIVPAPLTAEETAEVQRLAVAAFDAASCEGLVRADFFLTEDD FT EFVINEINTMPGFTPISMYPQMWQASGVSYPELVDRLVQAALRRPTGLR" FT misc_feature 77775..77810 FT /note="PS00843 D-alanine-D-alanine ligase signature 1." FT CDS complement(78732..78965) FT /transl_table=11 FT /gene="SCO5561" FT /gene_synonym="SC7A1.05c" FT /product="hypothetical protein SC7A1.05c" FT /note="SC7A1.05c, conserved hypothetical protein, len: 77 FT aa; similar to several putative /hypotheticals eg. FT TR:O28868 (EMBL:AE001007) proposed transcriptional FT regulatory protein from Archaeoglobus fulgidus (77 aa) FT fasta scores; opt: 123, z-score: 217.3, E(): 8.3e-05, FT (31.9% identity in 69 aa overlap)." FT /db_xref="GOA:Q9ZBR8" FT /db_xref="InterPro:IPR019887" FT /db_xref="UniProtKB/TrEMBL:Q9ZBR8" FT /protein_id="CAA22404.1" FT /translation="MVQAYILIQTEVGKASTVAETISKLPGVIQAEDVTGPYDVIVRAQ FT SDTVDELGRMVVAKVQQVDGITRTLTCPVVHL" FT CDS 79199..80167 FT /transl_table=11 FT /gene="SCO5562" FT /gene_synonym="SC7A1.06" FT /product="putative thiamine monphosphate kinase" FT /note="SC7A1.06, thiL, thiamine monphosphate kinase, len: FT 322aa; similar to many eg. TR:P95118 (EMBL:Z83018) FT hypothetical protein from Mycobacterium tuberculosis (333 FT aa) fasta scores; opt: 959, z-score: 1227.0, E(): 0, (51.1% FT identity in 319 aa overlap) and THIL_SALTY thiamine FT monphosphate kinase from Salmonella typhimurium (325 aa) FT fasta scores; opt: 511, z-score: 350.3, E(): 3.2e-12, FT (35.9% identity in 329 aa overlap). Note: thiAB FT (arbitrarily named) previously mapped to this region of the FT chromosome." FT /db_xref="GOA:Q9ZBR7" FT /db_xref="InterPro:IPR006283" FT /db_xref="UniProtKB/TrEMBL:Q9ZBR7" FT /protein_id="CAA22405.1" FT /translation="MKGTVGELGEFGLIRELTSRLTTTPAVRVGPGDDAAVVAAPDRRV FT VASTDILVEGRHFRRDWSTAYDVGRKAAAQNLADIAAMGAVPTALLLGLVVPAELPVTW FT PTELMDGLRDECQVAGASVVGGDVVRGDTITVSITALGDLRNQEPVTRAGAQPGDLVAV FT TGWLGWSAAGFAVLSRGFRSPRAFVEAHRRPEPPYHAGPAAAGLGATAMCDVSDGLIAD FT LGHIAEASKVRIDVRSGQIDIPSQMNDIGQAVGVDPMQWVLTGGEDHAIVATFPPDVKL FT PARWKVIGEVLNPSALPQVTVDGAPWTSKGGWDHFGGDVES" FT CDS 80164..80973 FT /transl_table=11 FT /gene="SCO5563" FT /gene_synonym="SC7A1.07" FT /product="phosphomethylpyrimidine kinase" FT /note="SC7A1.07, thiD, phosphomethylpyrimidine kinase , FT len: 269aa; similar to many eg. SW:THID_SALTY ThiD, FT phosphomethylpyrimidine kinase from Salmonella typhimurium FT (266 aa) fasta scores; opt: 588, z-score: 737.2, E(): 0, FT (42.1% identity in 259 aa overlap). Note: thiAB FT (arbitrarily named) previously mapped to this region of the FT chromosome." FT /db_xref="GOA:Q9ZBR6" FT /db_xref="HSSP:1JXH" FT /db_xref="InterPro:IPR004399" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZBR6" FT /protein_id="CAA22406.1" FT /translation="MTAPTPPVTPPLVLTVAGSDSGGGAGIQADLKTMLALGTHGMSVL FT TAVTAQNSRGVQGAWELPVEAVRAQYRSVVDDIGVQAVKTGMLSSAELVETVAELLAGT FT DAPAVVDPVGVSKHGDALLASSALESVRTRLLPVATVATPNLDEVAQLTGVRVDDETDL FT RRAAAAVLAFGPRWALIKGGHLAGDAVDLLTDGSEEHWLRAPRLDNRHTHGTGCTLASA FT VACGLAKGQSVPVAVRAAKEYVTGAITAGFPLGGGIGPVDHGWALGE" FT CDS complement(81059..81244) FT /transl_table=11 FT /gene="SCO5564" FT /gene_synonym="SC7A1.08c" FT /product="putative 50S ribosomal protein L28" FT /note="SC7A1.08c, rpmB, 50S ribosomal protein L28, len: FT 61aa; similar to many including SW:RL28_BACSU RpmB 50S FT ribosomal protein L28 from Bacillus subtilis (62 aa) fasta FT scores; opt: 171, z-score: 301.8, E(): 1.6e-09, (41.0% FT identity in 61 aa overlap). Contains Pfam match to entry FT PF00830 Ribosomal_L28, Ribosomal L28 family, score 74.50, FT E-value 2.2e-18." FT /db_xref="GOA:Q9ZBR5" FT /db_xref="InterPro:IPR001383" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZBR5" FT /protein_id="CAA22407.1" FT /translation="MAANCDVCGKGPGFGNNISHSHRRTSRRWNPNIQRVRTVVSGTPK FT RVNACTSCIKAGKVSR" FT misc_feature complement(81062..81238) FT /note="Pfam match to entry PF00830 Ribosomal_L28, Ribosomal FT L28 family, score 74.50, E-value 2.2e-18." FT CDS 81511..83280 FT /transl_table=11 FT /gene="SCO5565" FT /gene_synonym="SC7A1.09" FT /product="conserved hypothetical protein SC7A1.09" FT /note="SC7A1.09, unknown, len: 589 aa; similar to several FT hypothetical proteins eg.TR:O34751 (EMBL:Z99112) YLOV FT protein from Bacillus subtilis (553 aa) fasta scores; opt: FT 656, z-score: 464.3, E(): 1.4e-18, (28.9% identity in 582 FT aa overlap) and to TR:AAK47378 (EMBL:AE007126) FT Mycobacterium tuberculosis CDC1551 hypothetical protein FT MT3052, 470 aa; fasta scores: opt: 772 Z-score: 726.0 E(): FT 8.3e-33; 40.974% identity in 493 aa overlap" FT /db_xref="GOA:Q9ZBR4" FT /db_xref="InterPro:IPR019986" FT /db_xref="UniProtKB/TrEMBL:Q9ZBR4" FT /protein_id="CAA22408.1" FT /translation="MAQVPQRFFDALAVRTWCGLSLRALGRAREEIDAINVYPVADGDT FT GTNLYLTVESAAAAVEAVFAAHELDAGARGASESPGGASLSPGAAGQAPPGAGDGPSLA FT DAVGAMAHGALIGARGNSGTILAQLLRGMAQVLTAGGDSGRAEGAGLRRALRHAAASAR FT QAVAHPVEGTVLTVASAAADAADGAEGGCAEVARAAYEGARAALAATPGQLPALERAGV FT VDAGGHGLVTVLAALVETFTGRVPGPVAVPHARAERGGEGLADAHAPAGECATETAAEE FT NGPAFEVIYLLEAEDAAVARLRQRLDALGDSLVVVGGDGLWNVHVHVDDAGAAVEAGVE FT AGRPYRIRITHFGHGDAHTTKAERPPRERAQRAVVAVVPGEGLAALYAEAGATTLLARP FT GEPPASGELVQAVRRAHAREVVLLPNDAELRHTAAAAAEQARTEGIRVALIPTRSAVQG FT IAALAVHEPERRFDEDVVAMTSAAGATRHAEVTVAEHQSWTTAGICQAGDVLGLIDGDV FT AVIGADVSQVAATVLDRMLSAGGELVTLVLGDAAPRAVADRLEARVREAYLAVDTVVYR FT GGRQGALLLVGVE" FT CDS 83343..85571 FT /transl_table=11 FT /gene="SCO5566" FT /gene_synonym="SC7A1.10" FT /product="putative ATP-dependent DNA helicase" FT /note="SC7A1.10, recG, ATP-dependent DNA helicase, len: FT 742aa; similar to many eg. SW:RECG_ECOLI ATP-dependent DNA FT helicase from Escherichia coli (693 aa) fasta scores; opt: FT 438, z-score: 1301.5, E(): 0, (35.7% identity in 723 aa FT overlap). Contains PS00017 ATP /GTP-binding site motif A FT (P-loop) and Pfam match to entry PF00271 helicase_C, FT Helicases conserved C-terminal domain, score 67.50, E-value FT 2.8e-16." FT /db_xref="GOA:Q9ZBR3" FT /db_xref="HSSP:1GM5" FT /db_xref="InterPro:IPR019793" FT /db_xref="UniProtKB/TrEMBL:Q9ZBR3" FT /protein_id="CAA22409.1" FT /translation="MDPVPALQEPLKKVLGPATAKVMAEHLGLHTVGDLLHHYPRRYEE FT RGQLTHLADLPMDEHVTVVAQVADARLHTFASSKAPRGKGQRLEVTITDGSGRLQLVFF FT GNGVHKPHKELLPGTRAMFAGKVSVFNRRLQLAHPAYELLRGGDDEGEAAESVESWAGA FT LIPLYPATAKLESWKLAKAIQTVLPSAQEAVDPLPGSLREGRGLVSLPEALLKIHRPHT FT KADIEDARARLKWDEAFVLQVALARRRHAESQLPAVPRKPGADGLLTAFDDRLPFTLTD FT GQRKVSREIFDDLATDHPMHRLLQGEVGSGKTLVALRAMLAVVDSGGQAVMLAPTEVLA FT QQHHRSVVEMMGELAEGGMLGGAEHATKVVLLTGSMGAAARRHALLDLATGEAGIVIGT FT HALIEDKVQFHDLGLVVVDEQHRFGVEQRDALRGKGKQPPHLLVMTATPIPRTVAMTVF FT GDLETSVLDQLPAGRSPIASHVVPAADKPHFLARAWERVREEVSNGHQAYVVCPRIGDE FT DDDPGKGAKQSKQPPEGDADKRPPLAVLDVAEQLARGPLQGLGVEVLHGRMQPDDKDAV FT MRRFAAGETDVLVATTVIEVGVNVPNATAMVIMDADRFGVSQLHQLRGRVGRGSAPGLC FT LLVSEMPEASAARQRLNAVASTRDGFELSRIDLEQRREGDVLGQAQSGARTSLRVLAVI FT EDEEIIAEARQEAAAVVAADPELTGLPGLRTALEALLDEEREQYLEKG" FT misc_feature 84258..84281 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)." FT misc_feature 84987..85232 FT /note="Pfam match to entry PF00271 helicase_C, Helicases FT conserved C-terminal domain, score 67.50, E-value 2.8e-16" FT CDS 85627..86214 FT /transl_table=11 FT /gene="SCO5567" FT /gene_synonym="SC7A1.11" FT /product="putative DNA methylase" FT /note="SC7A1.11, possible DNA methylase, len: 195aa; FT similar to many hypotheticals some of which contain PS00092 FT N-6 Adenine-specific DNA methylases signature eg. FT SW:YHHF_ECOLI hypothetical protein from Escherichia coli FT (198 aa) fasta scores; opt: 340, z-score: 430.7, E(): FT 1.1e-16, (35.8% identity in 193 aa overlap). Contains FT PS00092 N-6 Adenine-specific DNA methylases signature FT although not in the expected N-terminal region." FT /db_xref="GOA:Q9ZBR2" FT /db_xref="InterPro:IPR016065" FT /db_xref="UniProtKB/TrEMBL:Q9ZBR2" FT /protein_id="CAA22410.1" FT /translation="MTRVIAGKAGGRRLAVPPGTGTRPTSDRAREGLFSTWQSLLGGPL FT DGERVLDLYAGSGAVGLEALSRGAGHVLLVEADARAARTVRANVDSLGLPGAEVRAGRA FT EQIIRTPAPAEPYDVVFLDPPYAVSDDDLREILLTLRTEGWLGTEALVTVERSTRGGEF FT RWPHGFEAIRARRYGEGTFWYGRAASTCEDAR" FT misc_feature 85984..86004 FT /note="PS00092 N-6 Adenine-specific DNA methylases FT signature." FT CDS 86241..86720 FT /transl_table=11 FT /gene="SCO5568" FT /gene_synonym="SC7A1.12" FT /gene_synonym="coaD" FT /product="phosphopantetheine adenylyltransferase" FT /note="SC7A1.12, coaD, phosphopantetheine FT adenylyltransferase, len: 159 aa; strong similarity to many FT including SW:COAD_ECOLI phosphopantetheine FT adenylyltransferase (EC 2.7.7.3) CoaD or KdtB or B3634 from FT Escherichia coli (159 aa) fasta scores: opt: 485 Z-score: FT 587.5 E(): 4.5e-25; 45.513% identity (45.806% ungapped) in FT 156 aa overlap" FT /db_xref="GOA:Q9ZBR1" FT /db_xref="HSSP:1QJC" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZBR1" FT /protein_id="CAA22411.1" FT /translation="MRRAVCPGSFDPITNGHLDIIARASSLYDEVYVAVMINQAKKGLF FT EIEERIDLIRRVTAEYGNVRVESFHGLLVDFCKQREIPAIVKGLRAVSDFDYELQMAQM FT NNGLSGVETLFIPTNPTYSFLSSSLVKEVATWGGDVAHLVPPLVLEALTERLRNR" FT CDS 86854..87993 FT /transl_table=11 FT /gene="SCO5569" FT /gene_synonym="SC7A1.13" FT /product="hypothetical protein SC7A1.13" FT /note="SC7A1.13, unknown, len: 379 aa; similar to TR:O69467 FT (EMBL:AL023635) hypothetical protein from Mycobacterium FT tuberculosis (245 aa) fasta scores; opt: 254, z-score: FT 388.8, E(): 2.3e-14, (29.5% identity in 234 aa overlap). FT Contains probable coiled-coil from 82 to 124 (43 residues) FT Max score: 1.615 (probability 1.00)." FT /db_xref="UniProtKB/TrEMBL:Q9ZBR0" FT /protein_id="CAA22412.1" FT /translation="MDVQNKLDEITAMVSGARAMPMSASCVVNRAELLSMLEELRAELP FT GSLAQAQELIGDREQMVAQARQEADRIIEGAHAERGSLIADTEVARRSQAEADRILAEA FT RQEAEEVRAEADDYVDSKLANFEVVLTKTLGSVGRGREKLLGTGPGLDENGYEDEDAPE FT RSHDPETLRRDADAYVDTKLGAFEAVLAKTLDAVGRGRQKLHGRIATDDLGALADDMTT FT VQHSSDADYLAGLAGLADAPASAPAPAEQQGQPQYGEQQPVAARMPAQAVPEMPSQEPV FT YGYASQQQPDPYAAYQQTYDGGPDPYGYQQQGADPYAYQYDGGQQAYDAQQGYAQPPQP FT QQPPHAPQTHPQALDETSLFDTSMISAEQLRAYEQGRGL" FT CDS 88138..88791 FT /transl_table=11 FT /gene="SCO5570" FT /gene_synonym="SC7A1.14" FT /product="hypothetical protein" FT /note="SC7A1.14, unknown, len: 217 aa; similar to FT Y06F_MYCTU hypothetical protein from Mycobacterium FT tuberculosis (207 aa) fasta scores; opt: 244, z-score: FT 699.9, E(): 1.1e-31, (45.5% identity in 189 aa overlap)." FT /db_xref="InterPro:IPR003772" FT /db_xref="UniProtKB/TrEMBL:Q9ZBQ9" FT /protein_id="CAA22413.1" FT /translation="MVLNARLDHRDPLVFDTHELGRRPGALQRLTRTVDAPKDFGLQGV FT IGVPEGAPVELDLRLESVMEGVLVTGTARARAAGECVRCLEPLEQQLEADFQELFSYPD FT ADDRGRPVAEPGDDAEDDEDRFFVEDGLIGLEPVLRDAVVLALPMQPVCQEDCRGLCSQ FT CGVRLSDDPDHHHDAVDIRWAALQGLAGSLGDGEKDEMSGDGADSADAAEKQEK" FT CDS 88794..88967 FT /transl_table=11 FT /gene="SCO5571" FT /gene_synonym="SC7A1.15" FT /product="50S ribosomal protein L32" FT /note="SC7A1.15, rpmF, 50S ribosomal protein L32, len: 57 FT aa; similar to many eg. SW:RL32_BACST 50S PrmF, ribosomal FT protein L32 from Bacillus stearothermophilus (56 aa) fasta FT scores; opt: 180, z-score: 341.1, E(): 1.1e-11, (48.1% FT identity in 54 aa overlap)." FT /db_xref="GOA:Q9ZBQ8" FT /db_xref="InterPro:IPR002677" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZBQ8" FT /protein_id="CAA22414.1" FT /translation="MAVPKRKMSRSNTRHRRSQWKAAVPTLVACERCHEPKLQHIACPA FT CGTYNKRQVLEV" FT CDS 88987..89805 FT /transl_table=11 FT /gene="SCO5572" FT /gene_synonym="SC7A1.16" FT /product="ribonuclease III" FT /note="SC7A1.16, rnc, ribonuclease III, len: 272aa; similar FT to many eg. SW:RNC_ECOLI rnc, ribonuclease III from FT Escherichia coli (226 aa) fasta scores; opt: 492, z-score: FT 612.9, E(): 7.7e-27, (40.9% identity in 220 aa overlap). FT Contains PS00517 Ribonuclease III family signature, Pfam FT match to entry PF00636 Ribonuclease_3, RNase3 domain., FT score 147.60, E-value 2.2e-40 and Pfam match to entry FT PF00035 dsrm, Double-stranded RNA binding motif, score FT 47.10, E-value 4e-10." FT /db_xref="GOA:Q9ZBQ7" FT /db_xref="HSSP:1DI2" FT /db_xref="InterPro:IPR011907" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZBQ7" FT /protein_id="CAA22415.1" FT /translation="MSVPKKAEDAKADPPAKKKADTQASSHTLLEGRLGYQLESALLVR FT ALTHRSYAYENGGLPTNERLEFLGDSVLGLVVTDTLYRTHPDLPEGQLAKLRAAVVNSR FT ALAEVGRGLELGSFIRLGRGEEGTGGRDKASILADTLEAVIGAVYLDQGLDAASELVHR FT LFDPLIEKSSNLGAGLDWKTSLQELTATEGLGVPEYLVTETGPDHEKTFTAAARVGGVS FT YGTGTGRSKKEAEQQAAESAWRSIRAAADERAKATADAVDADPDEASASA" FT misc_feature 89173..89199 FT /note="PS00517 Ribonuclease III family signature." FT misc_feature 89173..89445 FT /note="Pfam match to entry PF00636 Ribonuclease_3, RNase3 FT domain., score 147.60, E-value 2.2e-40" FT misc_feature 89527..89724 FT /note="Pfam match to entry PF00035 dsrm, Double-stranded FT RNA binding motif, score 47.10, E-value 4e-10" FT repeat_region 89818..89863 FT /note="inverted repeat" FT misc_feature 89914..90750 FT /note="Pfam match to entry PF01149 Fapy_DNA_glyco, FT Formamidopyrimidine-DNA glycosylase, score 390.10, E-value FT 2.2e-113" FT CDS 89914..90774 FT /transl_table=11 FT /gene="SCO5573" FT /gene_synonym="SC7A1.17" FT /product="formamidopyrimidine-DNA glycosylase" FT /note="SC7A1.17, fpg, formamidopyrimidine-DNA glycosylase, FT len: 286aa; similar to many eg. TR:O69470 (EMBL:AL023635) FT putative formamidopyrimidine-DNA glycosylase from FT Mycobacterium leprae (282 aa) fasta scores; opt: 1075, FT z-score: 1367.9, E(): 0, (59.8% identity in 286 aa overlap) FT and SW:FPG_ECOLI formamidopyrimidine-DNA glycosylase from FT Escherichia coli(269 aa) fasta scores; opt: 508, z-score: FT 712.6, E(): 2.1e-32, (36.2% identity in 282 aa overlap). FT Contains Pfam match to entry PF01149 Fapy_DNA_glyco, FT Formamidopyrimidine-DNA glycosylase, score 390.10, E-value FT 2.2e-113." FT /db_xref="GOA:Q9ZBQ6" FT /db_xref="HSSP:1K82" FT /db_xref="InterPro:IPR012319" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZBQ6" FT /protein_id="CAA22416.1" FT /translation="MPELPEVEVVRRGLERWAAHRTVADVEVLHPRAVRRHVAGPDDFA FT HRLKDHRIGTPSRRGKYLWLPLEDTDQAVLAHLGMSGQLLVQPHETPAEKHLRIRVRFA FT DALGTELRFVDQRTFGGLSLHDTSADGLPDVIAHIARDPLDPLFDDEAFHHALRRKRTT FT IKRALLDQSLISGVGNIYADEALWRARLHYERPTATLTRPRTTELLGHVRDVMNAALAV FT GGTSFDSLYVNVNGESGYFDRSLDAYGREGMPCRRCATPMRRRPWMNRSSYFCPKCQRP FT PRVTP" FT CDS complement(90764..91189) FT /transl_table=11 FT /gene="SCO5574" FT /gene_synonym="SC7A1.18c" FT /product="conserved hypothetical protein SC7A1.18c" FT /note="SC7A1.18c, conserved hypothetical protein, len: FT 141aa; similar to many eg. SW:YTFH_ECOLI from Escherichia FT coli (156 aa) fasta scores; opt: 396, z-score: 679.8, E(): FT 1.4e-30, (48.9% identity in 131 aa overlap) Also similar to FT SC1F2.10 (EMBL:AL031350) unknown protein from Streptomyces FT coelicolor (135 aa) fasta scores; opt: 305, z-score: 398.0, FT E(): 2.2e-17 (42.4% identity in 132 aa overlap)." FT /db_xref="InterPro:IPR002577" FT /db_xref="UniProtKB/TrEMBL:Q9ZBQ5" FT /protein_id="CAA22417.1" FT /translation="MLAYAGGMSTTQERTAEQDLPFDVFSRACPSRGTLEHVTGRWGAL FT TLGALYEGSFRFNELRRRVDGVSEKMLAQTLHALERDGLVHREAQPTNPPRVDYELTAL FT GHEVAGRLLALIECVEGRMDEVLASRERYDERRMPTA" FT CDS complement(91276..92466) FT /transl_table=11 FT /gene="SCO5575" FT /gene_synonym="SC7A1.19c" FT /product="putative transmembrane protein" FT /note="SC7A1.19c, possible transmembrane protein, len: FT 396aa; some similarity to TR:O31398 (EMBL:AJ222587) FT hypothetical, protein from Bacillus subtilis (257 aa) opt: FT 341, z-score: 212.5, E(): 0.00015, (39.5% identity in 167 FT aa overlap). GC rich 17100-17400. Contains possible FT transmembrane region." FT /db_xref="GOA:Q9ZBQ4" FT /db_xref="InterPro:IPR014044" FT /db_xref="UniProtKB/TrEMBL:Q9ZBQ4" FT /protein_id="CAA22418.1" FT /translation="MGRHRRSAAGRAAEGHQPDGTAGRRRDPLAPDAGEAPTMGIAPYL FT NPEAYAEVRAKSDAYLFADAPDGEGPQAGRTVAFPRDGYTPTGGSQPGGGRRRRRKRAA FT TPVRTGLLGVSAAVAIGTVAVATGVVPGLDNYRIGGNSGGGDRVQAQDTPTNGPSQQGG FT TSGSADTGRGGDAATSRGTDRSPSSAPSAPSAQSPSKGASAEDSPSSSPSSASPSTSAP FT ASKPAAPAGTPSKTKKPKTPPSAEPKPTTPSRPATKEPAKPSAPAAVSEEAVAQAQVLK FT LVNDERAKVGCSPVAANSALRELAEDFSRAMATQGFFDHTDPSGATPWDRASAAGISGL FT GGENIARGQADAQAVMDAWMNSPDHRANILNCDFQTLGVGVHFGSGGPWWTQDFGY" FT CDS 92650..92931 FT /transl_table=11 FT /gene="SCO5576" FT /gene_synonym="SC7A1.20" FT /product="putative acylphosphatase" FT /note="SC7A1.20, acy, possible acylphosphatase, len: 93aa; FT similar to SW:ACYP_MYCTU putative acylphosphatase from FT Mycobacterium tuberculosis (93 aa) opt: 345, z-score: FT 576.5, E(): 8.2e-25, (58.9% identity in 90 aa overlap) and FT SW:ACYO_CHICK acylphosphatase from chicken (Gallus gallus) FT (98 aa) opt: 150, z-score: 208.0, E(): 0.00027, (45.0% FT identity in 60 aa overlap). Contains PS00150 FT Acylphosphatase signature 1. While acylphosphatases have FT been so far only characterized in vertebrates, there are a FT number of bacterial and archebacterial hypothetical FT proteins that are highly similar to that enzyme and that FT probably possess the same activity." FT /db_xref="GOA:Q9ZBQ3" FT /db_xref="HSSP:2ACY" FT /db_xref="InterPro:IPR017968" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZBQ3" FT /protein_id="CAA22419.1" FT /translation="MSEDVRLVAWVRGQVQGVGFRWFTRARALELGGMSGFALNLGDGR FT VQVVAEGPRERCEGLLEWLRGDDTPGRVDGVTEIWDTPRGGYEGFAIR" FT misc_feature 92680..92712 FT /note="PS00150 Acylphosphatase signature 1." FT CDS 93834..97394 FT /transl_table=11 FT /gene="SCO5577" FT /gene_synonym="SC7A1.21" FT /product="putative chromosome associated protein" FT /note="SC7A1.21, possible chromosome associated protein, FT len: 1186aa; similar to many hypotheticals eg. FT SW:Y06B_MYCTU hypothetical protein from Mycobacterium FT tuberculosis (1289 aa) fasta scores; opt: 2637, z-score: FT 2806.3, E(): 0, (53.1% identity in 1205 aa overlap) with FT weak similarity to a family of chromosome associated FT proteins e.g. SW:SCII_CHICK chromosome scaffold protein FT SCII from chicken (Gallus gallus) (1189 aa) opt: 370, FT z-score: 383.3, E(): 4.7e-14, (22.6% identity in 1246 aa FT overlap). Contains PS00017 ATP /GTP-binding site motif A FT (P-loop). Also contains 2 probable coiled coil regions from FT 162 to 492 and from 654 to 1041." FT /db_xref="GOA:Q9ZBQ2" FT /db_xref="HSSP:1E69" FT /db_xref="InterPro:IPR011890" FT /db_xref="UniProtKB/TrEMBL:Q9ZBQ2" FT /protein_id="CAA22420.1" FT /translation="MHLKALTLRGFKSFASATTLRFEPGITCVVGPNGSGKSNVVDALS FT WVMGEQGAKSLRGGKMEDVIFAGTTGRPPLGRAEVSLTIDNSDGALPIEYAEVTITRIM FT FRNGGSEYQINGDTCRLLDIQELLSDSGIGREMHVIVGQGQLDSVLHADPMGRRAFIEE FT AAGVLKHRKRKEKALRKLDAMQANLARVQDLTDELRRQLKPLGRQAAVARRAAVIQADL FT RDARLRLLADDLVRMREALQAEVADEAALKERKEAAEQELGKALRREADLEDEVRRLTP FT RLQRAQQTWYELSQLAERVRGTISLADARVKSATSAPPEERRGRDPEELEREAARVREQ FT EAELEAALEAAEHALEDTAAHRADLERELAMEERRLKDAARAIADRRENLARLGGQVGA FT ARSRAAAAQAEIERLAQARDESGQRAAAAQEEYEALRAEVDGLDAGDQELAERHDAARR FT ALTEAEAALSAAREAATAAERQRAATQARHEALALGLRRKDGTGALLAAKDRLTGLLGP FT AAGLLTVTPGHEAALATAFGAAADALAVTSPAAAADAIRLLRKQDAGRAALLLAGAPDD FT VPHETRGDGPPHAADLVHGPADLMPAVRRLLRGIVVVATLEDAEDLVYARPALTAVTAE FT GDLLGAHFAQGGSAGAPSLLEVQASVDQAAAELAELGVRCEELAGEQEAAAGRRRECAA FT LVEELGERRRAADREKSSVAQQLGRLAGQARGAAGEAERSAAAAERAQEALDKALTEVE FT ELAERLAVAEEMPVEEEPDTAARDRLAADGANARQTEMEARLQVRTHEERVKGLAGRAD FT SLDRAARAEREARARAEQRRARLRHEAAVAEAVAAGARQLLAHVEVSLSRADEERTLAE FT AAKARREQELTAARTAGRDLKAELDKLTDSVHRGEVLGAEKRLRIEQLETKALEELGVE FT PAGLAAEYGPHQEVPPSPPADGEVLPEDPEHPRNRPRPFVRAEQEKRLKTAERAYQQLG FT KVNPLALEEFAALEERHQFLSEQLEDLKKTRADLLQVVKEVDERVEQVFTEAFRDTARE FT FEGVFSRLFPGGEGRLILTDPDNMLTTGVDVEARPPGKKVKRLSLLSGGERSLTAVAML FT VSIFKARPSPFYVMDEVEAALDDTNLQRLIRIMQELQEASQLIVITHQKRTMEVADALY FT GVSMQGDGVSKVISQRLRQP" FT misc_feature 93924..93947 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)." FT CDS 97582..99000 FT /transl_table=11 FT /gene="SCO5578" FT /gene_synonym="SC7A1.22" FT /product="putative sugar transporter" FT /note="SC7A1.22, sugar transporter, len: aa; similar to FT many eg. SW:GLCP_SYNY3 glucose transport protein from FT Synechocystis sp. (468 aa) fasta scores; opt: 1477, FT z-score: 1527.5, E(): 0, (50.6% identity in 468 aa FT overlap). Contains PS00217 Sugar transport proteins FT signature 2, PS00216 Sugar transport proteins signature 1 FT and Pfam match to entry PF00083 sugar_tr, Sugar (and other) FT transporter, score 404.10, E-value 1.3e-117. Also contains FT several possible transmembrane regions." FT /db_xref="GOA:Q9ZBQ1" FT /db_xref="InterPro:IPR005828" FT /db_xref="UniProtKB/TrEMBL:Q9ZBQ1" FT /protein_id="CAA22421.1" FT /translation="MASTSQAPSPGAGTAHPDHLGHVIFIAAAAAMGGFLFGYDSSVIN FT GAVEAIRDRYDVGSAVLAQVIAVALIGCAIGAATAGRIADRIGRIRCMQIAAVLFTVSA FT VGSALPFALWDLAMWRIIGGFAIGMASVIGPAYIAEVSPPAYRGRLGSFQQAAIVIGIA FT VSQLVNWGLLNAAGGDQRGELMGLEAWQVMLGVMVIPAVLYGLLSFAIPESPRFLISVG FT KRERAKKILEEVEGKDVDFDARVTEIEHAMHREEKSSFKDLLGGSFFFKPIVWIGIGLS FT VFQQFVGINVAFYYSSTLWQSVGVDPADSFFYSFTTSIINIVGTVIAMIFVDRVGRKPL FT ALIGSVGMVIGLALEAWAFSFDLVDGKLPATQGWVALIAAHVFVLFFALSWGVVVWVFL FT GEMFPNRIRAAALGVAASAQWIANWAITASFPSLADWNLSGTYVIYTIFAALSIPFVLK FT FVKETKGKALEEMG" FT misc_feature 97657..99006 FT /note="Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter, score 404.10, E-value 1.3e-117" FT misc_feature 97945..98022 FT /note="PS00217 Sugar transport proteins signature 2." FT misc_feature 98563..98616 FT /note="PS00216 Sugar transport proteins signature 1." FT CDS complement(99126..100583) FT /transl_table=11 FT /gene="SCO5579" FT /gene_synonym="SC7A1.23c" FT /product="putative transmembrane protein" FT /note="SC7A1.23c, possible transmembrane protein, len: FT 485aa; similar to many putative and hypothetical proteins FT eg. EMBL:E1312898 putative transmembrane transport protein FT from Streptomyces coelicolor (476 aa) fasta scores; opt: FT 482, z-score: 311.0, E(): 5e-10, (26.4% identity in 473 aa FT overlap) Also weakly similar to SW:BETT_ECOLI high-affinity FT choline transport protein from Escherichia coli (677 aa) FT opt: 74, z-score: 196.3, E(): 0.0012, (23.0% identity in FT 283 aa overlap). Contains several possible transmembrane FT regions. Also similar to SC1C2.05c (EMBL:AL031124) possible FT transmembrane transport protein from Streptomyces FT coelicolor (476 aa) fasta scores; opt: 482, z-score: 215.0, FT E(): 3.4e-07, (26.4% identity in 473 aa overlap)" FT /db_xref="GOA:Q9ZBQ0" FT /db_xref="InterPro:IPR001248" FT /db_xref="UniProtKB/TrEMBL:Q9ZBQ0" FT /protein_id="CAA22422.1" FT /translation="MSKTAENEGALETRGIEQVPDHERTARTRELFPTWVGANISVLLL FT TMGASLVVAYRLNFWQALVVAGAAPVVSYGLVGLIGIAGKRGGAPGMALSRAVFGQRGN FT LLPGSLIWVARWGWETINAVTGAYALLTVLDIVFGIRANSVLDMVTLLAFVVATFAISG FT LGINAVQKCNKYAAYLFGAFSVLVLGYLVVDTDWSAVFDRSAGSVAAMITGVGLIAAGG FT VSWIPSAPDFTRYLPRTASSKGIVGVTVGGAGIVVLPMVLMGAVMAVSTPDLASAADPV FT SFLGEILPTWIAVPYLLIALIGMLLINSMSMYSAGFTAQTLGFKVPRHWAVSVNAVISL FT VFGGVLMLVATSFMGSFIAFLSLLAVAFSAWVGVFGADMLRGREYDGEALADTGRTSAY FT WYRGGFSPAAVVAWAVGLAAGLMFTTSDWFTGPLATDNFVGEYGLGWVATVVISALLYA FT VLPKPALIVPDARAERAEQPEAETVTV" FT CDS 100738..101976 FT /transl_table=11 FT /gene="SCO5580" FT /gene_synonym="SC7A1.24" FT /product="putative prokaryotic docking protein" FT /note="SC7A1.24, ftsY, prokaryotic docking protein, len: FT 412aa; similar to many including SW:FTSY_ECOLI functional FT homolog of the mammalian SRP receptor (docking protein) FT from Escherichia coli (497 aa) fasta scores; opt: 885, FT z-score: 906.8, E(): 0, (40.7% identity in 388 aa overlap). FT Contains PS00017 ATP /GTP-binding site motif A (P-loop), FT PS00300 SRP54-type proteins GTP-binding domain signature FT and Pfam match to entry PF00448 SRP54, SRP54-type protein, FT score 323.90, E-value 1.8e-93. Contains possible FT hydrophobic membrane spanning region" FT /db_xref="GOA:Q9ZBP9" FT /db_xref="HSSP:1OKK" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9ZBP9" FT /protein_id="CAA22423.1" FT /translation="MPGVTHTGPVMEIVILAVVIAVVVIGALGGLVVGSRRKKQLPEPP FT PATPDITAPPAEPHVGDEAETPRDETRRTIEEVDLPDGGTATVEEPPVVEELEIPQIEV FT PEPTAGRLVRLRARLSRSQNALGKGLLTLLSREHLDDDTWEEIEDTLLTADVGVQPTQE FT LVERLRERVKVLGTRTPEELRTLLREELITLVGPDMDREVKTEPATSKPGIVMVVGVNG FT TGKTTTTGKLARVLVADGRSVVLGAADTFRAAAADQLQTWGERVGAHTVRGPEGGDPAS FT VAFDAVKEGKEMGSDVVLIDTAGRLHTKTGLMDELGKVKRVVEKHAPLDEVLLVLDATT FT GQNGLIQARVFAEVVNITGIVLTKLDGTAKGGIVVAVQRELGVPVKLIGLGEGADDLAP FT FEPAAFVDALIGE" FT misc_feature 101155..101967 FT /note="Pfam match to entry PF00448 SRP54, SRP54-type FT protein, score 323.90, E-value 1.8e-93" FT misc_feature 101392..101415 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)." FT misc_feature 101887..101928 FT /note="PS00300 SRP54-type proteins GTP-binding domain FT signature." FT CDS complement(102101..102772) FT /transl_table=11 FT /gene="SCO5581" FT /gene_synonym="SC7A1.25c" FT /product="conserved hypothetical protein" FT /note="SC7A1.25c, hypothetical protein, len: 223 aa; FT similar to TR:Q9K3U7 (EMBL:AL359988) Streptomyces FT coelicolor conserved hypothetical protein SCD10.30c, 217 FT aa; fasta scores: opt: 514 Z-score: 547.5 E(): 7.3e-23; FT 44.974% identity in 189 aa overlap" FT /db_xref="InterPro:IPR015330" FT /db_xref="UniProtKB/TrEMBL:Q9ZBP8" FT /protein_id="CAA22424.1" FT /translation="MGFTIGIGSSRGMREIRSGARRRGRPSECTVVAEFSGLWGWDVVP FT GARTAQGACSCGLPDCPAPGAHPLDFAPRVPAGATLDEASEAWSRFPGAAVMLAVGRTF FT DVIEVAEPAGLRALARLERMGVPLGPVAATPQGRAQFFVAPGAAAELPRLLYRMGWDDP FT AALDLRGLGPGTYLTAPPSDRGGRGPVRWLRPPALDSATKPPAARLLLGTLAYVAHRSR FT A" FT CDS 103219..104721 FT /transl_table=11 FT /gene="SCO5582" FT /gene_synonym="SC7A1.26" FT /product="putative regulator" FT /note="SC7A1.26, possible regulator, len: 500aa; similar to FT TR:Q53958 (EMBL:M80614) sporulation-associated protein from FT Streptomyces coelicolor (473 aa) fasta scores; opt: 612, FT z-score: 589.9, E(): 1.5e-25, (31.3% identity in 485 aa FT overlap) and TR:E1319689 (EMBL:AL031541) putative FT transcriptional regulator from Streptomyces coelicolor (446 FT aa) fasta scores; opt: 279, z-score: 413.7, E(): 9.5e-16, FT (25.9% identity in 478 aa overlap)" FT /db_xref="UniProtKB/TrEMBL:Q9ZBP7" FT /protein_id="CAA22425.1" FT /translation="MSGNGGSGTSAGSASHADKRPNELLTSWFARSGWSKGELARQVNR FT RARQLGANHISTDTSRVRRWLDGENPREPIPRILSELFSERFGVVVSVEDLGLRSTRPT FT PSATGVDLPWTGPQTVALLSEFSRSDLMLARRGFLGSSLALSAGPSLIEPMQRWLVPTP FT SATPAAAGSEPAAPANRARGRLSRPELDLLESTAVMFRRWDAQCGGGLRRKAVVGQLHE FT VTDLLQEPQTETTRAKLFKVAAELAELAGWMSYDVGLQPTAQKYFVLALHAAKEAGDRP FT LGSYILSSMSRQMIHLGRPDDALELIHLAQYGSRDCASPRTQSMLYAMEARAYANMGQP FT GRTKRAVRMAEDIFAEADEWDEPDPDWIRFFSEAELYGENSHSFRDLAYVAGRSPAYAS FT LADPLMRRAVELFAKDEEHQRSYALNLIGMATVHLLRREPEESTVLAMEAMGIAKKVRS FT ERVNTRIRKTVDTAVRDFGDLGEVVDLTERLAVELPETAEAV" FT CDS 105031..106377 FT /transl_table=11 FT /gene="SCO5583" FT /gene_synonym="SC7A1.27" FT /product="ammonium transporter" FT /note="SC7A1.27, amt, ammonium transporter, len: 448 aa; FT similar to many eg. TR:O67997 (EMBL:AF005275) (438 aa) FT fasta scores; opt: 1224, z-score: 1126.9, E(): 0, (47.1% FT identity in 414 aa overlap). Contains PS01219 Ammonium FT transporters signature and Pfam match to entry PF00909 FT Ammonium_transp, Ammonium Transporter Family, score 537.00, FT E-value 1.3e-157." FT /db_xref="GOA:Q9ZBP6" FT /db_xref="InterPro:IPR018047" FT /db_xref="UniProtKB/TrEMBL:Q9ZBP6" FT /protein_id="CAA22426.1" FT /translation="MAPAITLAAETELSAANTGFMLICSALVMLMTPALAFFYGGMVRV FT KSTLNMLMMSFISLGIVTVLWVLYGFSMAFGTDSGSVVGWNSDWVGLSDIGLTELWDGY FT TIPVFVFLVFQLMFAVLTPALISGALADRVKFTAWALFIALWATIVYFPVAHWVWGAGG FT WAFELGVIDFAGGTAVHINAGAAALGVILVIGKRVGFKKDPMRPHSLPLVMLGAGLLWF FT GWFGFNAGSWLGNDDGVGALMFVNTQVATGAAVLGWLAYEKIRHGAFTTLGAASGAVSG FT LVAITPAGGAVSPLGAIAVGLVAGVVCAMAVGLKYRFGYDDSLDVVGVHLVGGILGSLL FT IGFFASGKGQSDVEGLFYGGGLDQFWKQCAGVFGVLAYSLVVSAVLAFLLDKTIGMRVS FT EDVEVAGIDQAEHAETAYDFSGAGGGAARTTATPAASTAGSAPSKKVDA" FT misc_feature 105085..106281 FT /note="Pfam match to entry PF00909 Ammonium_transp, FT Ammonium Transporter Family, score 537.00, E-value FT 1.3e-157" FT misc_feature 105544..105621 FT /note="PS01219 Ammonium transporters signature." FT misc_feature 106374..106643 FT /note="Pfam match to entry PF00543 P-II, Nitrogen FT regulatory protein P-II, score 116.60, E-value 7.1e-34" FT CDS 106374..106712 FT /transl_table=11 FT /gene="SCO5584" FT /gene_synonym="glnB" FT /gene_synonym="SC7A1.28" FT /product="nitrogen regulatory protein P-II" FT /note="SC2E1.01, glnB, nitrogen regulatory protein P-II, FT partial CDS, len: >54 aa; highly similar to many e.g. FT GLNB_AZOBR (112 aa), fasta scores; opt: 198 z-score: 381.9 FT E(): 4.9e-14, 50.0% identity in 54 aa overlap" FT /note="SC7A1.28, partial CDS, glnB, nitrogen regulatory FT protein P-II, len: 92aa; similar to many eg. SW:GLNB_RHIME FT nitrogen regulatory protein P-II from Rhizobium meliloti FT (112 aa) fasta scores; opt: 402, z-score: 776.2, E(): 0, FT (58.7% identity in 92 aa overlap). Contains PS00496 P-II FT protein urydylation site and Pfam match to entry PF00543 FT P-II, Nitrogen regulatory protein P-II, score 116.60, FT E-value 7.1e-34." FT /db_xref="GOA:Q8CJR0" FT /db_xref="HSSP:1HWU" FT /db_xref="InterPro:IPR015867" FT /db_xref="UniProtKB/TrEMBL:Q8CJR0" FT /protein_id="CAD55357.1" FT /translation="MKLITAVVKPHRLDEIKEALQAFGVHGLTVTEASGYGRQRGHTEV FT YRGAEYTVDLVPKIRIEVLVEDDDAEQLIDVVVKAARTGKIGDGKVWAVPVDTAVRVRT FT GERGPDAL" FT misc_feature 106509..106526 FT /note="PS00496 P-II protein urydylation site." FT misc_feature 106547..106652 FT /note="Overlap with Streptomyces coelicolor cosmid 2E1 FT (EMBL:AL023797)." FT CDS 106777..109284 FT /transl_table=11 FT /gene="SCO5585" FT /gene_synonym="glnD" FT /product="putative protein pII uridylyltransferase" FT /note="SC2E1.02, probable glnD, protein pII FT uridylyltransferase, len: 835 aa; similar to many e.g. FT GLND_ECOLI (890 aa), fasta scores; opt: 403 z-score: 540.4 FT E(): 7.3e-23, 26.2% identity in 851 aa overlap. Contains 7 FT degenerate repeats of the sequence PSS" FT /db_xref="GOA:O69873" FT /db_xref="InterPro:IPR013546" FT /db_xref="UniProtKB/Swiss-Prot:O69873" FT /protein_id="CAA19377.1" FT /translation="MTDEAEDSGPGGYAAARLRLLTEGARSGPPRRRALAELTDGWLAG FT LFGAATEEHTGISLVAVGGYGRGELSPRSDLDLLLLHDGRDDKAVAALADRLWYPVWDL FT GIDLDHSVRTPQQARKTAGQDLKVHLGLLDARHLAGDLGLTASLRTAVLADWRNQAPKR FT LPELRDLCAERAERQGELQFLLEPDLKEARGGLRDATALRAVAASWLADAPREGLAEAR FT RRLLDVRDALHLATGRATDRLALQEQDQVAAELGLLDADALLRQVYEAARVISYAGDVT FT WREVGRVLRSRSVRPRLRAMMNGRNGGKPVAERSPLAEGVVEQDGEAVLARTARPERDP FT ALPLRAAAAAAQAGLPLSRHAVRRLAATARPLPTPWPAEAREQLVTLLGSGRPTVQVWE FT ALEAEGLVTRLLPDWERVRCRPQRNAVHLWTVDRHLIETAVRAAGFTRRVHRPDLLLIA FT ALLHDIGKGWPGDHSVAGETIARDVAARIGFDGADTAVLATLVRHHLLLVETATRRDLD FT DPATVRAVAQAVGTEHTLELLHALTEADALATGPAAWSSWRGSLVADLVKRVSGVLAGE FT PQPEAESAAPTAEQERLAVEAFRTGGPVLALRAQTEPPADSAPAPSSPSSPSFPSPLSS FT PSSPSSADGPEPLGVELLIAVPDQAGVLPAVAGVLAMHRLTVRTAELRSVPLPDGVEGS FT VLLLDWRVAAQYGSLPQAARLRADLVRALDGTLDIAARLAERDAAHPRRRGVEPPPPRV FT TVAPAASRLATVIEVRAQDAPGLLFRLGRALEAAGVRVRSAHVSTLGANAVDAFYVTRG FT EGTPLPGDEAASVARGLEESLRT" FT repeat_region 108637..108699 FT /note="7 degenerate 9bp repeats" FT RBS 109265..109269 FT /note="possible RBS upstream of ffh" FT CDS 109281..110933 FT /transl_table=11 FT /gene="SCO5586" FT /gene_synonym="ffh" FT /product="signal recognition particle protein" FT /note="SC2E1.03, ffh, signal recognition particle protein, FT len: 550 aa; highly similar to mnay e.g. SR54_ECOLI (453 FT aa), fatsa scores; opt: 1465 z-score: 1282.8 E(): 0, 50.0% FT identity in 458 aa overlap. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop), PS00300 SRP54-type FT proteins GTP-binding domain signature and Pfam match to FT entry SRP54 PF00448, SRP54-type proteins, score 66.57. FT Similarities suggest possible start site at aa 35" FT /db_xref="GOA:O69874" FT /db_xref="HSSP:2FFH" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:O69874" FT /protein_id="CAA19378.1" FT /translation="MTVRSVQRAGTLCLPGRIPWRTTHTNADARTYAAVFDTLSDRLSA FT TFKSLRGKGRLTEADIDATAREIRIALLEADVALPVVRAFIKKVKERSLGAEVSKALNP FT AQQVLKIVNEELVGILGGETRRLRFAKQPPTVIMLAGLQGAGKTTLAGKLGHWLKEQGH FT SPLLVACDLQRPNAVNQLSVVAERAGVAVYAPEPGNGVGDPVKVAKDSIEFAKAKVHDL FT VIVDTAGRLGIDQELMQQAADIRDAVSPDEILFVVDAMIGQDAVNTAEAFRDGVGFDGV FT VLSKLDGDARGGAALSIASVTGKPIMFASNGEKLDDFDAFHPDRMASRILDMGDLLTLI FT EQAEKTFSQEEAEKMASKLASKKGQDFTLDDFLAQMEQVRKMGSISKLLGMLPGMGQMK FT DQINNLDERDVDRTAAIIKSMTPGERQEPTIINGSRRARIAKGSGVEVSAVKNLVERFF FT EARKMMSRMAQGGGMPGMPGMPGMGGGPGRQKKQQKKAKGKQRSGNPMKRKQQEQEEAA FT RRAAAAQSGGALGLPQQGGQDFELPDEFKKFMG" FT misc_feature 109701..109724 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 110112..110243 FT /note="Pfam match to entry SRP54 PF00448, SRP54-type FT proteins, score 66.57" FT misc_feature 110193..110234 FT /note="PS00300 SRP54-type proteins GTP-binding domain FT signature" FT stem_loop 110951..110999 FT /note="hairpin loop with 22/23 bp stem" FT CDS 111050..112996 FT /transl_table=11 FT /gene="SCO5587" FT /gene_synonym="ftsH" FT /product="cell division protein FtsH homolog" FT /note="SC2E1.04, ftsH, cell division protein FtsH homolog FT (zinc metalloprotease, integral membrane protein), len: 648 FT aa; similar to many e.g. FTSH_LACLA (695 aa), fasta scores; FT opt: 1489 z-score: 1195.5 E(): 0, 41.7% identity in 640 aa FT overlap. Contains PS00017 ATP/GTP-binding site motif A FT (P-loop), PS00674 AAA-protein family signature and Pfam FT matches to entry AAA PF00004, ATPases associated with FT various cellular activities (AAA) and to entry zn-protease FT PF00099, Zinc-binding metalloprotease domain, score 22.07, FT score 357.96. Proline-rich N-terminus is not present in FT other ftsH homologs" FT /db_xref="GOA:O69875" FT /db_xref="HSSP:1LV7" FT /db_xref="InterPro:IPR003960" FT /db_xref="UniProtKB/TrEMBL:O69875" FT /protein_id="CAA19379.1" FT /translation="MTNPSPPRKAPEPPWRTEGTPDEPPKPPPGGRRMRGGWWNLILAA FT LIVYLIANLVLSFFNEGDEPTISYTEFSKQVDEGNVSKIYAKGDAIQGQLKKARDNPEG FT DGTYTKFTTERPTFADDQLWADLTKNRVTVTAEPVVQHRSFLANLLIALAPMLILVVLW FT IFIARRMRGALGGGAGGMLGRKAPPKPVELEAGKPRTTFADVAGIDEVEGELSDVVDFL FT KNPDAYRRMGAKMPRGVLLTGPPGTGKTLLARAVAGEAGVPFFSASASEFIEMIVGVGA FT SRVRELFAEARKVAPSIIFIDEIDTIGRARGGGSGTGGHDEREQTLNQILTEMDGFSGS FT EGVIVIAATNRADILDAALTRPGRFDRVVSVSPPDRGGREAILEIHTREIPLAPDIDLA FT QVARTTPGMTGAELANLANEAALLAVKRKQERVTQANLSEALEKVQLGAERPLVMPEEE FT RRRTAYHESGHALLGMLQPGADPVRKITIVPRGRALGVTLSTPDADKYAYTEEYLRGRI FT IGALGGMAAEHVVYGMITTGSESDLEQVTNIARGMVARWGMSERVGRLSALPGDAQQAY FT GLAAAPQTLDAIDGEMRRVVDSCYEEAVRKLRDHRGQLDALAESLLASETLDEADAYRI FT AGITRLTKDDPEA" FT misc_feature 111761..112327 FT /note="Pfam match to entry AAA PF00004, ATPases associated FT with various cellular activities (AAA), score 357.96" FT misc_feature 111776..111799 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 112076..112132 FT /note="PS00674 AAA-protein family signature" FT misc_feature 112430..112477 FT /note="Pfam match to entry zn-protease PF00099, FT Zinc-binding metalloprotease domain, score 22.07" FT CDS complement(113014..113631) FT /transl_table=11 FT /gene="SCO5588" FT /gene_synonym="SC2E1.05c" FT /product="putative lipoprotein" FT /note="SC2E1.05c, probable lipoprotein, len: 205 aa; FT contains N-terminal signal sequence and appropriately FT positioned PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT /db_xref="UniProtKB/TrEMBL:O69876" FT /protein_id="CAA19380.1" FT /translation="MPHRTTALRLAAPVAVLALALTACGGGDDDSGTDAKGGATTEATT FT QASPSPSQPASGGDMAQGESASGKVAEGPGEVTYDVLAQKVEVGTEAEAAKAVADAADA FT KGKVLATAHIKYTHQGGPALTEGSDVHDGTTVFADGQRGGVLIGAAEDAPGCEDPYDAE FT SWKQGESHVFCETYVIPAGATSVEVHWSEEDGEPYVWKFPQK" FT misc_feature complement(113560..113592) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS complement(113638..113642) FT /note="possible RBS upstream of Sc2E1.05c" FT CDS complement(113782..114669) FT /transl_table=11 FT /gene="SCO5589" FT /gene_synonym="SC2E1.06c" FT /product="hypothetical protein SC2E1.06c" FT /note="SC2E1.06c, unknown, len: 295 aa" FT /db_xref="UniProtKB/TrEMBL:O69877" FT /protein_id="CAA19381.1" FT /translation="MTPTLVRQHSSHAQATPHVDPRARARDWSEIQERMLVPLYEAVYE FT RLDVGGDTRMLGLNCGSGLALLMAASRGAAVTGVDSRSPELLDLARRRLLSGTSGDPGA FT DSTVSTRTRGDAPRIVQGTPGDAADPTAPAFTLVTAFEPGGCRAGDSETLGDLLARATP FT LAARGAAVVLAGWGPPERCATTSVLRVAAKLTDPTHGTGGWRPALRDDLEEVAQRAGLR FT PDGSGRVACPFGYADTGSAVRGLLSTGMFDAAVAATDRDQVDKELTEALHPYQRPDGTV FT WMPNVFRYLIARVR" FT CDS 115339..115935 FT /transl_table=11 FT /gene="SCO5590" FT /gene_synonym="SC2E1.07" FT /product="hypothetical protein SC2E1.07" FT /note="SC2E1.07, unknown, len: 198 aa" FT /db_xref="UniProtKB/TrEMBL:O69878" FT /protein_id="CAA19382.1" FT /translation="MSTTPPVLAAELAQAWADIQRHHTELPDLAAPESLIGESSSACGH FT ELSFERLLHEAVHGIAAARGVRDTSRAGRYHNRRFLAIAEELGLDHPEEPHPSSGFSLV FT TLTPEAKRRYRPTIERLQRALKAHTVATATDTARSFRGPAARHGSSGGGVRVKAVCDCG FT RNVRVVPSVLAQAPIMCGGCGKPFRIPEVVGAGMS" FT RBS 116175..116179 FT /note="possible RBS upstream of rpsP" FT CDS 116191..116610 FT /transl_table=11 FT /gene="SCO5591" FT /gene_synonym="rpsP" FT /product="30S ribosomal protein S16" FT /note="SC2E1.08, rpsP, 30S ribosomal protein S16, highly FT similar to many e.g. RS16_MYCTU (162 aa), fatsa scores; FT opt:480 z-score: 771.3 E(): 0, 56.3% identity in 144 aa FT overlap. Contains PS00732 Ribosomal protein S16 signature" FT /db_xref="GOA:O69879" FT /db_xref="HSSP:1EMW" FT /db_xref="InterPro:IPR000307" FT /db_xref="UniProtKB/Swiss-Prot:O69879" FT /protein_id="CAA19383.1" FT /translation="MAVKIKLKRLGKIRSPHYRIVVADSRTRRDGRAIEEIGKYHPTYN FT PSVMEVDAERVAYWLGVGAQPTEPVLAILKKTGDWQKFKGEPAPAPLLQPAEKAARPSF FT EAIGGEDEGKGEAITQKKKADKKDEAAAESSASEA" FT misc_feature 116197..116226 FT /note="PS00732 Ribosomal protein S16 signature" FT RBS 116602..116605 FT /note="possible RBS upstream of SC2E1.09" FT CDS 116613..116852 FT /transl_table=11 FT /gene="SCO5592" FT /gene_synonym="SC2E1.09" FT /product="conserved hypothetical protein SC2E1.09" FT /note="SC2E1.09, unknown, len: 79 aa; highly similar to FT small hypothetical proteins from several organisms, e.g. FT YX40_MYCTU MTCY274.40c (80 aa), fasta scores; opt: 356 FT z-score:628.4 E(): 9.1e-28, 71.6% identity in 74 aa FT overlap" FT /db_xref="GOA:P0A4Q4" FT /db_xref="InterPro:IPR004088" FT /db_xref="UniProtKB/Swiss-Prot:P0A4Q4" FT /protein_id="CAA19384.1" FT /translation="MLEEALEHLVKGIVDNPDDVQVASRNLRRGRVLEVRVHPDDLGKV FT IGRNGRTARALRTVVGAIGGRGVRVDLVDVDHVR" FT RBS 116949..116953 FT /note="possible RBS upstream of SC2E1.10" FT CDS 116964..117530 FT /transl_table=11 FT /gene="SCO5593" FT /gene_synonym="SC2E1.10" FT /product="putative 16S rRNA processing protein" FT /note="SC2E1.10, probable 16S rRNA processing protein, len: FT 188 aa; similar to hypothetical proteins from many FT organisms e.g. YX38_MYCTU MTCY274.38c (176 aa), fasta FT scores; opt: 479 z-score: 693.1 E(): 2.3e-31, 48.3% FT identity in 176 aa overlap. Also some similarity to FT RIMM_HAEIN 16S rRNA processing protein rimM (178 aa), fasta FT scores; opt: 210 z-score: 174.2 E(): 0.018, 27.6% identity FT in 170 aa overlap and to SW:RIMM_ECOLI (EMBL:X01818) FT Escherichia coli 16S rRNA processing protein RimM or B2608, FT 182 aa; fasta scores: opt: 216 Z-score: 258.0 E(): 9.8e-07; FT 24.561% identity in 171 aa overlap" FT /db_xref="GOA:P0A4D3" FT /db_xref="InterPro:IPR002676" FT /db_xref="UniProtKB/Swiss-Prot:P0A4D3" FT /protein_id="CAA19385.1" FT /translation="MQLVVARIGRAHGIKGEVTVEVRTDEPELRLGPGAVLATDPASTG FT PLTIESGRVHSGRLLLRFAGVHDRTGAEALRNTLLIADVDPDERPEDEDEYYDHQLIDL FT DVVTEDGTEVGRITEISHLPTQDLFVVERPDGSEVYVPFVSEIVTGIDLDAQRAVIDPP FT PGLIDDRAEIASARDAGAEDAGDEA" FT RBS 117522..117525 FT /note="possible RBS upstream of trmD" FT CDS 117530..118363 FT /transl_table=11 FT /gene="SCO5594" FT /gene_synonym="trmD" FT /product="tRNA (guanine-N1)-methyltransferase" FT /note="SC2E1.11, trmD, probable tRNA FT (guanine-N1)-methyltransferase, len: 277 aa; similar to FT many e.g. TRMD_ECOLI (EC2.1.1.31) (255 aa), fasta scores; FT opt: 437 z-score: 660.6E(): 1.5e-29, 41.2% identity in 238 FT aa overlap" FT /db_xref="GOA:P0A4P1" FT /db_xref="HSSP:1UAJ" FT /db_xref="InterPro:IPR002649" FT /db_xref="UniProtKB/Swiss-Prot:P0A4P1" FT /protein_id="CAA19386.1" FT /translation="MRLDVVTIFPEYLEPLNVSLVGKARARGQLGVHVHDLRDWTYDRH FT NTVDDTPYGGGPGMVMKTEPWGDALDSVLADGYETGCGEPALVVPTPSGRPFTQELAVH FT LSERPWLIFTPARYEGIDRRVVDEYATRMPVYEVSIGDYVLAGGEAAVLVVTEAVARLL FT PGVLGNAESHRDDSFAPGAMANLLEGPVHTKPPQWRGRGIPDVLLSGHHGKIARWRRDE FT ALRRTTANRPDLIERCDPAAFDKKDREMLSILGWQPDPDGEPYGRFWRRTPGMEE" FT RBS 118485..118488 FT /note="possible RBS upstream of rplS" FT CDS 118500..118850 FT /transl_table=11 FT /gene="SCO5595" FT /gene_synonym="rplS" FT /product="50S ribosomal protein L19" FT /note="SC2E1.12, rplS, 50S ribosomal protein L19, len: FT 116aa; highly similar to many e.g. RL19_MYCTU (113 aa), FT fastascores; opt: 571 z-score: 1138.4 E(): 0, 77.3% FT identity in110 aa overlap. Contains PS01015 Ribosomal FT protein L19 signature" FT /db_xref="GOA:P0A477" FT /db_xref="InterPro:IPR018257" FT /db_xref="UniProtKB/Swiss-Prot:P0A477" FT /protein_id="CAA19387.1" FT /translation="MSHLLDSVDAASLRSDVPAFRPGDTVNVHVRVIEGNRSRVQQFKG FT VVIRRQGAGVRETFTVRKVSFSVGVERTFPVHTPIVEKIELVTRGDVRRAKLYYLRELR FT GKAAKIKEKRDS" FT misc_feature 118761..118802 FT /note="PS01015 Ribosomal protein L19 signature" FT CDS 118896..119675 FT /transl_table=11 FT /gene="SCO5596" FT /gene_synonym="sip1" FT /product="putative signal peptidase I" FT /note="SC2E1.13, sip1, probable signal peptidase I, len: FT 259 aa; similar to many e.g. LEP_HAEIN signal peptidase I FT (EC 3.4.21.89) (349 aa), fasta scores; opt: 162 z-score: FT 381.2 E(): 5.3e-14, 32.5% identity in 243 aa overlap, FT though with large internal deletions. Contains PS00761 FT Signal peptidases I signature 3, Pfam match to entry FT signal_pept_I PF00461, Signal peptidases I, score 51.12 and FT probable transmembrane domain. Also similar to downstream FT genes sip2 (E(): 9.7e-26, 44.9% identity in 274 aa FT overlap), sip3 (E(): 4.8e-16, 35.6% identity in 264 aa FT overlap) and sip4 (E(): 8.7e-08, 37.0% identity in 219 aa FT overlap). Contains possible hydrophobic membrane spanning FT region" FT /db_xref="GOA:O69884" FT /db_xref="HSSP:1B12" FT /db_xref="InterPro:IPR019759" FT /db_xref="UniProtKB/TrEMBL:O69884" FT /protein_id="CAA19388.1" FT /translation="MDTETQHTERDRSSRPSDSEQPSEPEGPEERSRSAFTGRIGDWLP FT GGRITVTLLILLLFLLLVSTFVLQPFQIPSGSMERGLRIGDRVLVNKLAYRFDGRPRRG FT DIVVFDGTGSFGHGDYIKRVVGVGGDHVVCCDEEGRVRVNGQPVDESAFLYPGDRPSTV FT PFDVVVPDGTLFVLGDHRSDSSDSRDHLGSPGGGMVPLDDVIGRADWIVWPFGHATRLD FT RPDAYARVPDAEAGAGAASGAGAAPDPGAAPDGDADG" FT stem_loop 118915..119001 FT /note="hairpin loop with 34/41 bp stem" FT misc_feature 119055..119345 FT /note="Pfam match to entry signal_pept_I PF00461, Signal FT peptidases I, score 51.12" FT misc_feature 119415..119456 FT /note="PS00761 Signal peptidases I signature 3" FT CDS 119668..121008 FT /transl_table=11 FT /gene="SCO5597" FT /gene_synonym="sip2" FT /product="putative signal peptidase I" FT /note="SC2E1.14, sip2, probable signal peptidase I, len: FT 446 aa; similar to many e.g. LEP_HAEIN signal peptidase I FT (EC 3.4.21.89) (349 aa), fasta scores; opt: 151, z-score: FT 317.3 E(): 1.9e-10, 30.1% identity in 286 aa overlap. FT Contains PS00761 Signal peptidases I signature 3, Pfam FT match to entry signal_pept_I PF00461, Signal peptidases I, FT score 42.41 and probable transmembrane domain. Also similar FT to surrounding genes sip1 (E(): 9.7e-24, 44.9% identity in FT 274 aa overlap), sip3 (E(): 1.8e-28, 56.3% identity in 245 FT aa overlap), and sip4 (E(): 1.1e-09, 35.9% identity in 223 FT aa overlap). Note that after aa 325 the ORF overlaps the FT downstream sip3 gene SC2E1.15, and positional base FT preference suggests that translation is in the other frame. FT No error in the cosmid sequence can be found to account for FT this. Contains possible hydrophobic membrane spanning FT region" FT /db_xref="GOA:O69885" FT /db_xref="HSSP:1B12" FT /db_xref="InterPro:IPR019759" FT /db_xref="UniProtKB/TrEMBL:O69885" FT /protein_id="CAA19389.1" FT /translation="MGSRGKPRGAPSSPAENLLPTGSRRTAAPSGGRSRAERRKLQRKV FT KRRRRRGAVKEIPLLVGVAVLIALVLKTFLVQAFVIPSGSMEQTIRIGDRVLVDKLTPW FT FGSEPQRGDVVVFRDPGGWLQGEQTTKKDDPVVVKQVKEGLAFIGLLPSDDEKDLIKRV FT VGVGGDHVKCCDKQGRVTVNGVPLTEDYLYPGDRPSRTPFDVTVPEGRLWVMGDHRSNS FT ADSRAHQETDFGTVSQDEVVGRAMVIAWPFGHWTTLDEPKTYASVSDAASGSTAAPELS FT HRVAPYDPNAMMELPTPAELPLVMGVVGLRRIRGRRRQRVRSWRGGCGGWRTVRSRRRG FT EPRTPRGEVRSGRGRRPRLRTRLRNRGRQGDERTARAGRTQRRDGGRGSRRDATRDPAR FT GQEAALLLEGAADPGRHRAGARPADQDVPGAGVLDPVLLDGEHPSDR" FT misc_feature 119782..120030 FT /note="Pfam match to entry signal_pept_I PF00461, Signal FT peptidases I, score 42.41" FT misc_feature 120301..120342 FT /note="PS00761 Signal peptidases I signature 3" FT misc_feature 120405..121759 FT /note="97.8% match to EMBL:SLTK24SIP Y09474 Streptomyces FT lividans sip gene, from 5 to 1359" FT RBS 120631..120635 FT /note="possible RBS upstream of sip3" FT CDS 120641..121651 FT /transl_table=11 FT /gene="SCO5598" FT /gene_synonym="sip3" FT /product="putative signal peptidase I" FT /note="SC2E1.15, sip3, probable signal peptidase I, len: FT 336 aa; identical to, but longer than, S. lividans Sip FT TR:E1228248 (EMBL:Y09474) signal peptidase I (291 aa), FT fasta scores; opt: 1997 z-score: 2287.4 E(): 0, 99.7% FT identity in 291 aa overlap, and similar to many others e.g. FT LEP_PHOLA signal peptidase I (EC 3.4.21.89) (203 aa), fasta FT scores; opt:222 z-score: 404.9 E(): 2.6e-15, 37.9% identity FT in 232 aa overlap. Contains PS00761 Signal peptidases I FT signature 3, 2x Pfam match to entry signal_pept_I PF00461, FT Signal peptidases I, scores 48.83 and 46.79 and probable FT transmembrane domain. Also similar to surrounding genes FT sip1 (E(): 7.6e-20, 35.6% identity in 264 aa overlap), sip2 FT (E(): 0, 56.3% identity in 245 aa overlap) and sip4 (E(): FT 6.6e-15, 36.3% identity in 237 aa overlap). Note that a FT more upstream start was chosen due to positional base FT preference. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="GOA:O69886" FT /db_xref="HSSP:1B12" FT /db_xref="InterPro:IPR019759" FT /db_xref="UniProtKB/TrEMBL:O69886" FT /protein_id="CAA19390.1" FT /translation="MGDVAVGARSGHDGEENRGRPEERSGPAAVGAPDSGHGSGTEDGR FT VTNGQRGQDGHNGGTEDEGVGGTPPATPPAAKKQRSFWKELPILVGIALVLALLIKTFL FT VQAFSIPSSSMENTLQIGDRVLVDKLTPWFGSEPERGEVVVFHDPADWLAGEPTPDPNA FT LQTVLSWIGLMPSAEEKDLIKRVIGVAGDTVECNKTGPLKVNGKALNEPYVYPGNTPCS FT DDDQGGRFKVTVPEGKIWVMGDHRQNSRDSRYNQSDKNGGMVPVDEVVGRAIVVAWPMN FT RWGTLPVPDTFDQDGLQARSSAAAALSVAPQGLAVAGVVPFVWWRRRRTAPAETR" FT misc_feature 120848..121093 FT /note="Pfam match to entry signal_pept_I PF00461, Signal FT peptidases I, score 48.83" FT misc_feature 121178..121453 FT /note="Pfam match to entry signal_pept_I PF00461, Signal FT peptidases I, score 46.79" FT misc_feature 121355..121396 FT /note="PS00761 Signal peptidases I signature 3" FT RBS 121743..121748 FT /note="possible RBS upstream of sip4" FT CDS 121756..122532 FT /transl_table=11 FT /gene="SCO5599" FT /gene_synonym="sip4" FT /product="putative signal peptidase I" FT /note="SC2E1.16, sip4, probable signal peptidase I, len: FT 258 aa; similar to many e.g. LEPS_BACSU signal peptidase I FT (EC 3.4.21.89) (184 aa), fasta scores; opt: 258 z-score: FT 337.6 E(): 1.4e-11, 32.2% identity in 177 aa overlap. FT Contains Pfam match to entry signal_pept_I PF00461, Signal FT peptidases I, score 49.57 and probable transmembrane FT domain. Also similar to upstream genes sip1 (E(): 8.8e-10, FT 36.5% identity in 219 aa overlap), sip2 (E(): 3.8e-13, FT 35.9% identity in 223 aa overlap) and sip3 (E(): 8.1e-15, FT 35.4% identity in 237 aa overlap). Contains possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:O69887" FT /db_xref="HSSP:1B12" FT /db_xref="InterPro:IPR019759" FT /db_xref="UniProtKB/TrEMBL:O69887" FT /protein_id="CAA19391.1" FT /translation="MGGESTTRTVPRGGGANKGPVGSRTGQRLSGIAVALGLVLFLGGF FT AWGAVVYRPYTVPTSSMTPTIDAGDRVLAQRIDGADVRRGDVVVFKDATWANAPMVKRV FT VAVGGDTVSCCQQGKLKVNGKVIDEPYLPAGTPAEISDFQTVTVPEGRLFLLGDERRNS FT VDSTAHLTDAAAGTVSRGAVDARVDAVAWPMDGMLERPTGFRTLGDLSSPGPLRTVVVL FT VIAGAVLILGGAAYGPLAKRAAASRARKGAEPAGGR" FT misc_feature 121801..122151 FT /note="Pfam match to entry signal_pept_I PF00461, Signal FT peptidases I, score 49.57" FT CDS 122534..123052 FT /transl_table=11 FT /gene="SCO5600" FT /gene_synonym="SC2E1.17" FT /product="conserved hypothetical protein SC2E1.17" FT /note="SC2E1.17, unknown, len: 172 aa; similar to FT C-terminus of M. tuberculosis hypothetical protein FT TR:O06205 (EMBL:Z95387) MTCY1A10.24 (351 aa), fasta scores; FT opt: 345 z-score: 375.2 E(): 1.2e-13, 44.7% identity in 161 FT aa overlap. Contains PS00893 mutT domain signature and Pfam FT match to entry mutT PF00293, Bacterial mutT protein, score FT 37.78" FT /db_xref="GOA:O69888" FT /db_xref="InterPro:IPR020084" FT /db_xref="UniProtKB/TrEMBL:O69888" FT /protein_id="CAA19392.1" FT /translation="MTPAGQDTYEGGLRRVARVVLLDPEDRILLLHGHEPDDPADDWWF FT TPGGGVEGDETRAEAARRELLEETGITDVELGPVLWRRRCSFPFAGRRWDQDEWYYLAR FT TARTATEAVGPGLTELERRSVAGARWWTCEELTRARETVYPTRLAELLTTLLDEGPPAG FT PVTLDTEIV" FT misc_feature 122615..122746 FT /note="Pfam match to entry mutT PF00293, Bacterial mutT FT protein, score 37.78" FT misc_feature 122678..122737 FT /note="PS00893 mutT domain signature" FT CDS 123109..123417 FT /transl_table=11 FT /gene="SCO5601" FT /gene_synonym="SC2E1.18" FT /product="conserved hypothetical protein" FT /note="SC2E1.18, unknown, len: 102 aa; highly similar to M. FT tuberculosis hypothetical protein YX32_MYCTU MTCY274.32c FT (101 aa), fasta scores; opt: 515 z-score: 1085.2 E(): 0, FT 75.0% identity in 100 aa overlap" FT /db_xref="InterPro:IPR019592" FT /db_xref="UniProtKB/TrEMBL:O69889" FT /protein_id="CAA19393.1" FT /translation="MSAEDLEKYETEMELKLYREYRDVVGLFKYVIETERRFYLTNDYE FT MQVHSVQGEVFFEVSMADAWVWDMYRPARFVKQVRVLTFKDVNIEELNKSDLELPGG" FT CDS 123476..123868 FT /transl_table=11 FT /gene="SCO5602" FT /gene_synonym="SC2E1.19" FT /product="hypothetical protein" FT /note="SC2E1.19, unknown, len: 130 aa; similar to M. FT tuberculosis hypothetical protein YX29_MYCTU MTCY274.29c FT (128 aa), fasta scores; opt: 253 z-score: 276.8 E(): FT 3.5e-08, 39.7% identity in 121 aa overlap" FT /db_xref="GOA:O69890" FT /db_xref="InterPro:IPR003509" FT /db_xref="UniProtKB/Swiss-Prot:O69890" FT /protein_id="CAA19394.1" FT /translation="MIVGAGGGADMNARGAMGRYGETLAARRLTGAGMTVLERNWRCGR FT TGEIDIVARDGDVLVVCEVKTRRGGAFEHPMAAVTPDKAERLRRLAERWIQTHGGAPPG FT GVRIDLVGVLLPQRGAPVVEHARGVA" FT CDS 123868..125493 FT /transl_table=11 FT /gene="SCO5603" FT /gene_synonym="SC2E1.20" FT /product="conserved hypothetical protein SC2E1.20" FT /note="SC2E1.20, unknown ATP/GTP binding protein, len: 541 FT aa; similar to hypothetical proteins from many organisms FT e.g. YIFB_ECOLI (516 aa), fasta scores; opt: 356 z-score: FT 935.9 E(): 0, 37.0% identity in 513 aa overlap. Contains FT PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:O69891" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:O69891" FT /protein_id="CAA19395.1" FT /translation="MGFARTCSVALVGVEGVVVEVQADLEPGVAAFTLVGLPDKSLTES FT RDRVRAAVVNSGAQWPQKKLTVGLSPASVPKSGSGFDLAVAASVLGAAERIDPRVLADI FT VMIGELGLDGRVRPVRGILPAVLAAAEAGYEQVVVPECAAPEASLVPGVSVLGVRSLRQ FT LIAVLADEPVPEEEQDLQGRPDPLMAGLRMPGTGAATGMHGMGAAQHDHGHDLADVVGQ FT ESARTAVEVAAAGRHHLFLEGPPGAGKTMLAERLPAILPRLCRAESLEVTAVHSVAGLL FT PPGKPLIDVAPYCAPHHSATMQALVGGGPGIARPGAVSLAHRGVLFLDETPEFSSHALD FT ALRQPLEAGHVVIARSAGVVRFPARFLMVLAANPCPCGRFSRTDELCECPSSAIRRYQA FT RLSGPLLDRVDLRVEVERVTRSQLAGDGPRGDSTRAVADRVRAARDRAAARLAGTPWRS FT NSEVPGRELRTRWRAAAGALDEAERSLERGVLTARGLDRVLRVAWTVADLVGHDRPDAR FT DVALALQLRTGVPRGVPMALGALA" FT misc_feature 124594..124617 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 125490..126638 FT /transl_table=11 FT /gene="SCO5604" FT /gene_synonym="SC2E1.21" FT /product="conserved hypothetical protein SC2E1.21" FT /note="SC2E1.21, unknown, len: 382 aa; N-terminus is FT Gly-rich, C-terminus is similar to the N-terminus of FT several hypothetical proteins e.g. SW:SMF_ECOLI SMF protein FT (374 aa), fasta scores; opt: 402 z-score: 277.5 E(): FT 3.2e-08, 40.7% identity in 194 aa overlap. This ORF appears FT to be interrupted by the following prophage at around aa FT 360, and to continue as the last part of SC2E1.37. The FT similarity to the M. tuberculosis hypothetical protein FT SW:YX27_MYCTU MTCY274.27c (389 aa) (fasta scores; opt: 603 FT z-score: 511.5 E(): 3e-21, 46.8% identity in 267 aa FT overlap) stops at that position and restarts in SC2E1.37. FT Alternative start site at aa 118 sugested by positional FT base preference" FT /db_xref="GOA:O69892" FT /db_xref="InterPro:IPR003488" FT /db_xref="UniProtKB/TrEMBL:O69892" FT /protein_id="CAA19396.1" FT /translation="MSGNTRPPEGAAPSGDTGPGTSGTLFPEAAVSFGGGSPAEGGAMT FT PPGAGDGPDGGEARWAGPGPGDGDGAVTGAGVAARGRSAAGTCGTGGGGAGSGARGGGP FT EDRELLGRVFLARVFEPGDEAGGRWVRERGAPEVVRRLREGGRALPGVSEKRWAGLCAR FT AGRADPGRDLAVARSAGARFVVPGTAEWPGQLDDLGDARPLGLWVRGGPSLRMWALRSV FT AVVGARACTEYGAHMAATLAAGLAERGWVVVSGGAYGIDGAAHRGALGAGGATAAVLAC FT GVDRPYPPGHTALITRIAEQGLVVGELPPGDHPTPSRFILRNRVIAALTRGTVVVEAAH FT RSGSLVTARAARRLGRHVMGVPTPLSGGAALAPIRFRLATAT" FT misc_feature 126567..139382 FT /note="probable prophage: has low GC (approx 66-68%), and FT some ORF's with similarities to bacteriophage ORF's. The FT ORF SC2E1.21 appears to have been interrupted by this FT prophage and apparently continues as the last part of FT SC2E1.37" FT CDS 126817..127128 FT /transl_table=11 FT /gene="SCO5605" FT /gene_synonym="SC2E1.22" FT /product="hypothetical protein SC2E1.22" FT /note="SC2E1.22, unknown prophage gene, len: 103 aa" FT /db_xref="UniProtKB/TrEMBL:O69893" FT /protein_id="CAA19397.1" FT /translation="MTTQNSNHPCACGSYAFEVLIHENVGGDKVWQQKTTGCAATTQST FT FAPGHDAKLKSLLIAAGVGGHPVRQTTRDTVVVKDALKVAADLGWRDLVGEAIAKGSS" FT CDS complement(127125..127415) FT /transl_table=11 FT /gene="SCO5606" FT /gene_synonym="SC2E1.23c" FT /product="hypothetical protein SC2E1.23c" FT /note="SC2E1.23c, unknown prophage gene, len: 96 aa" FT /db_xref="UniProtKB/TrEMBL:O69894" FT /protein_id="CAA19398.1" FT /translation="MTTRYPALPQSYAITRDRDTVIPRYLVVTALRGGQMAGLSIRVYK FT IVGETGETEEVSAREWSVDQMPNLPLIDTRWPLCLCWKCNGNGTKGELRRR" FT RBS 127458..127462 FT /note="possible RBS upstream of SC2E1.23" FT misc_feature 127466..127645 FT /note="Pfam match to entry gntR PF00392, Bacterial FT regulatory proteins, gntR family, score 43.92" FT CDS 127466..127660 FT /transl_table=11 FT /gene="SCO5607" FT /gene_synonym="SC2E1.24" FT /product="putative transcriptional regulator" FT /note="SC2E1.24, possible prophage transcriptional FT regulator, len:64 aa; similar to the N-terminus of several FT regulatory proteins e.g. Streptomyces phaeochromogenes FT plasmid pJV1 TR:Q54677 (EMBL:U23762) traR (245 aa), fasta FT scores; opt:137 z-score: 268.5 E(): 1e-07, 39.3% identity FT in 61 aa overlap. Contains Pfam match to entry gntR FT PF00392, Bacterial regulatory proteins, gntR family, score FT 43.92" FT /db_xref="GOA:O69895" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:O69895" FT /protein_id="CAA19399.1" FT /translation="MAEIISKRIADGTYPPGTRVPGIVELSAEFGIAASTAQKALAHLR FT GTGEVRTELGLGTFVADAK" FT RBS 127746..127750 FT /note="possible RBS upstream of SC2E1.25" FT CDS 127755..128456 FT /transl_table=11 FT /gene="SCO5608" FT /gene_synonym="SC2E1.25" FT /product="hypothetical protein SC2E1.25" FT /note="SC2E1.25, unknown prophage gene, len: 233 aa. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:O69896" FT /protein_id="CAA19400.1" FT /translation="MATTDGDEPPEEREFLTGDTPFVRVREALERLAALNEGPRVEQRV FT DRVDQIQNVFIGQGQDTHGREVAERAATRLAEQRQKFHFDFLNHALKQAEWTFRLSVWF FT MTGGALVILAGAVLALVHAGNPDLSYLPLVTSLTGALITVGGGALALHSKRAMANLTKA FT AEDNENKIDIDHKLEVATTFIDRVQDSQAKDRLNSAAALKALGMDAQPETMVNRLLPDP FT QTKEIDPGEPT" FT CDS complement(128515..128712) FT /transl_table=11 FT /gene="SCO5609" FT /gene_synonym="SC2E1.26c" FT /product="hypothetical protein SC2E1.26c" FT /note="SC2E1.26c, unknown prophage gene, len: 65 aa; very FT hydrophobic. Contains possible hydrophobic membrane FT spanning region" FT /db_xref="UniProtKB/TrEMBL:O69897" FT /protein_id="CAA19401.1" FT /translation="MNLPLGVKVLIVVICTLISVIVAMVAGFLSHASGSSVGQAILYGG FT GAFAGSLLLCLAVLSALGVL" FT RBS complement(128723..128726) FT /note="possible RBS upstream of SC2E1.26c" FT CDS complement(129051..129413) FT /transl_table=11 FT /gene="SCO5610" FT /gene_synonym="SC2E1.27c" FT /product="hypothetical protein SC2E1.27c" FT /note="SC2E1.27c, unknown prophage gene, len: 120 aa; FT contains hydrophobic region near centre. Contains possible FT hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:O69898" FT /protein_id="CAA19402.1" FT /translation="MSEIPAIRRRRASQFDHIDCGRADECPVHEPLLGHPTRKVPSQLD FT GAMTLAILAVAGVVSIFLFALKGVLDQVPDVIDSASRARDAWQRFKRKANEPPSPTVLR FT ELPPPAEDEQEPPAAA" FT CDS 130177..130392 FT /transl_table=11 FT /gene="SCO5611" FT /gene_synonym="SC2E1.28" FT /product="putative transcriptional regulator" FT /note="SC2E1.28, possible prophage transcriptional FT regulator, len: 71 aa; similar to the N-terminus of many FT e.g. TR:Q37946 Salmonella typhimurium bacteriophage L FT repressor protein C2 (220 aa), fasta scores; opt: 127 FT z-score: 227.1 E():2e-05, 45.7% identity in 46 aa overlap. FT Contains probable helix-turn-helix motif at aa 21 to 42 FT (Score 1829, +5.42 SD)" FT /db_xref="GOA:O69899" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:O69899" FT /protein_id="CAA19403.1" FT /translation="MPARTFSPDALRQIRRQRGVTQYKLAASLGVHNTAISHYENGHRR FT PDVETLATIADVLGARMDDFVTARAA" FT RBS 130542..130547 FT /note="possible RBS upstream of SC2E1.29" FT CDS 130554..132824 FT /transl_table=11 FT /gene="SCO5612" FT /gene_synonym="SC2E1.29" FT /product="putative ATP binding protein" FT /note="SC2E1.29, unknown prophage ATP binding protein, len: FT 756 aa; some similarity to TR:Q38030 (EMBL:X76288) FT Streptomyces Bacteriophage phi-C31 early region ORF9 (519 FT aa), fasta scores; opt: 360 z-score: 374.4 E(): 1.3e-13, FT 24.4% identity in 553 aa overlap, and to a putative FT prophage ORF from M. tuberculosis TR:O06608 (EMBL:Z95586) FT MTCY336.22 (471 aa), fasta scores; opt: 655 z-score: 535.5 FT E(): 1.4e-22, 29.8% identity in 416 aa overlap. Contains 2x FT PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="InterPro:IPR004968" FT /db_xref="UniProtKB/TrEMBL:O69900" FT /protein_id="CAA19404.1" FT /translation="MSYTTSEARDLAATQSGLDVPEHDTDRAAYFARLGFGVFPMPTNK FT KMPRAKGWPDLAMTTVEEVEEMWRSFTPSGWQNIALTLDGWTVVDVDPKNGGTASLEKL FT TAEYELPVTRTHHTASGPDSLHFIYRADPDRPIKSGPLSSRYPGIDIKTGRGSLIVAPG FT SVINGRRYEVVSAAEPAVAPSWLSEIRGDAQYPVVPSARSRTPSRASAGHSRAATLAEL FT RALPPDDPGRGNGWLTQVAGHLARNHTDHDSYLHELRAIDSESEVPHDKDRFMKTADSI FT WEREQAKERPKAAAPDKPKSILWHHEHTDLGNGRRLRDLHGEDMRHAPGWGWLTWDGRR FT WARGDGQARRFMHSVADAISEAIESMEEKQRSDDLMRWFGRSCSGPGISAALNEASVML FT PIETEISDFDADPHKLLVGNGVVDLRTGELLPVDRKYLLTRGTTVEYDPNADCPMWMDF FT LGWAFQGDIEMIEYIQRMFGMCLIGNNAHQVAFFLYGPGRSGKTTLTRVLSRLLGDYAT FT SADLSVFNESSSGHNEPLARLAGARLVVFSETRQGQRINEAQFKKFTGEDTLTASYKNK FT SWFEFLPAFTPVMFGNAQPSIAFDSGVERRMKVIPMRAQISDGQKNPKLVEQMMLNEGP FT AIMAWAVEGARLTAAESFVPDPPQVAQAVKEYKRENDHIGDFIEECLVFDEGATVASDV FT VWGRYSKWIEAGGVDFVKKADDRAGKSLLVRMLKTWSIENGTPIESFKSSNTRKLRGVA FT LND" FT misc_feature 132036..132059 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 132693..132716 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 133097..133100 FT /note="possible RBS upstream of SC2E1.30" FT CDS 133108..133659 FT /transl_table=11 FT /gene="SCO5613" FT /gene_synonym="SC2E1.30" FT /product="hypothetical protein SC2E1.30" FT /note="SC2E1.30, unknown prophage gene, len: 183 aa" FT /db_xref="UniProtKB/TrEMBL:O69901" FT /protein_id="CAA19405.1" FT /translation="MNDLDRRGGRIFGRVDGEVDWPSGVDSPYRLMKLRDPEKYEREVA FT RQVDAQRVIVEWAEWYGLKRAKMACCPRWLTHKVSRRCNSRCTAFGGGATDHRWLEHGV FT GWVLDGQPVALTSASYGISDEYRARFEWWVNEDPRLAVALGGQGWYGYGSTQVLVWRTD FT VIEVMEPAPESVRALGYPQY" FT CDS 134124..134315 FT /transl_table=11 FT /gene="SCO5614" FT /gene_synonym="SC2E1.31" FT /product="putative transcriptional regulator" FT /note="SC2E1.31, possible prophage transcriptional FT regulator, len: 63 aa; similar to the N-terminus of many FT e.g. TR:E264367 (EMBL:X87420) Salmonella typhimurium FT bacteriophage ES18 gene C2 (216 aa), fasta scores; opt: 133 FT z-score: 207.9E(): 0.00024, 35.8% identity in 53 aa FT overlap. Contains probable helix-turn-helix motif at aa 17 FT to 38 (Score 1786, +5.27 SD)" FT /db_xref="GOA:O69902" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:O69902" FT /protein_id="CAA19406.1" FT /translation="MFSGRKLKEARNKRGMSQAAVAARMGLSGLYVSYWENGRYAPNGV FT NMVLLLRALGCELEEVTE" FT RBS 134300..134305 FT /note="possible RBS upstream of SC2E1.32" FT CDS 134312..134662 FT /transl_table=11 FT /gene="SCO5615" FT /gene_synonym="SC2E1.32" FT /product="hypothetical protein SC2E1.32" FT /note="SC2E1.32, unknown prophage gene, len: 116 aa" FT /db_xref="UniProtKB/TrEMBL:O69903" FT /protein_id="CAA19407.1" FT /translation="MNAPETEFADAGWVAITRDEGGRVGVKPVRMFELTGEGVTALTKN FT ADGLMVPDPHAVEIINTDPLHAAKLAWLHKLVGVAERCTTDEARADLRRIAEWLIDWEP FT GDPGLRLADAEA" FT CDS 134730..135218 FT /transl_table=11 FT /gene="SCO5616" FT /gene_synonym="SC2E1.33" FT /product="hypothetical protein SC2E1.33" FT /note="SC2E1.33, unknown prophage gene, len: 162 aa; FT contains probable helix-turn-helix motif at aa 11 to 32 FT (Score 1192, +3.25 SD)" FT /db_xref="UniProtKB/TrEMBL:O69904" FT /protein_id="CAA19408.1" FT /translation="MVVVLAQQGIGRNEISRRTGISTASVSRIAAAHGIEFDGSQTEVA FT LKARIAELKARQAGIALGLVEDITSARGLLRMATTHRDFAFAAKAISDLTQSAQRMTPE FT ITNEEELEEAKEGLRDLYFQMGLMREGFEAKYGVPLDSDEGRELWDKARQEDMENEQP" FT RBS 135190..135195 FT /note="possible RBS upstream of SC2E1.34" FT CDS 135205..135621 FT /transl_table=11 FT /gene="SCO5617" FT /gene_synonym="SC2E1.34" FT /product="hypothetical protein SC2E1.34" FT /note="SC2E1.34, unknown prophage gene, len: 138 aa" FT /db_xref="UniProtKB/TrEMBL:O69905" FT /protein_id="CAA19409.1" FT /translation="MSNRDFSEDVQGPRSTDGPSVDDLRAEMYGGQVAGRFHYRESRTE FT RDSAVIQGTPVLGDGTMTDDQAAEIRKSFGIGADLRHAAQAAESYMDRRDPTSGHTIRT FT YGNGRVVDLDAEPTQTGSDRVEYPRVWYGDDPGA" FT RBS 136027..136030 FT /note="possible RBS upstream of SC2E1.35" FT CDS 136039..136482 FT /transl_table=11 FT /gene="SCO5618" FT /gene_synonym="SC2E1.35" FT /product="hypothetical protein SC2E1.35" FT /note="SC2E1.35, unknown prophage gene, len: 147 aa" FT /db_xref="UniProtKB/TrEMBL:O69906" FT /protein_id="CAA19410.1" FT /translation="MAATKVFRPEFKTRDGRKVSFGANYTHDTKAKRRAGLTTAGRPKV FT ETVGAGTVVRSPRRWLPWAVFGTNSAVLGGTWAVAELGPAVGGLVVGVALWAGYRIARW FT TAGEWAYFATKSRQIRGGRQVAEFASEGLPPQAHIPGEKVTRP" FT RBS 136783..136786 FT /note="possible RBS upstream of SC2E1.36" FT CDS 136794..137300 FT /transl_table=11 FT /gene="SCO5619" FT /gene_synonym="SC2E1.36" FT /product="hypothetical protein SC2E1.36" FT /note="SC2E1.36, unknown prophage gene, len: 168 aa" FT /db_xref="UniProtKB/TrEMBL:O69907" FT /protein_id="CAA19411.1" FT /translation="MAAKKTETAEATPCECSMYDALPADLTEEQVASGDFEVLTTGCTA FT TTKRQFAPGHDAKLKSALIRWGALGLEIRRNEGGVATSASPAKHAARYAFAHMVTAGVK FT RAEAKAAEKAERAAARAAKKAAPAPEVIKAKVGRVTYQGRMDGDHFVYEVKGQERRTLK FT FQPAA" FT CDS 137370..139760 FT /transl_table=11 FT /gene="SCO5620" FT /gene_synonym="SC2E1.37" FT /product="putative recombinase" FT /note="SC2E1.37, unknown prophage gene, len: 796 aa; shows FT very limited similarity to Rhodococcus opacus TR:G2935035 FT (EMBL:AF003948) putative transposase homolog (242 aa), FT fasta scores; opt: 215 z-score: 280.3 E(): 2.2e-08, 33.3% FT identity in 105 aa overlap; and similar to TR:O69933 FT (EMBL:AL023861) Streptomyces coelicolor putative DNA FT recombinase SC3C8.24, 672 aa; fasta scores: opt: 1276 FT Z-score: 1340.7 bits: 258.7 E(): 4.8e-67; 41.074% identity FT in 689 aa overlap. Contains PS00397 Site-specific FT recombinases active site and Pfam match to entry FT recombinase PF00239, Site-specific recombinases, score FT 36.16. The last part of this ORF (aa 672 onwards) appears FT to be a continuation of SC2E1.21, which was interrupted by FT the prophage; the similarities to YX27_MYCTU MTCY274.27c FT (389 aa) (fasta scores; opt: 246 z-score: 225.9 E(): FT 2.4e-05, 38.8% identity in 116 aa overlap) continue after FT aa 672. Contains probable coiled-coil from aa 449 to 505" FT /db_xref="GOA:O69908" FT /db_xref="InterPro:IPR006119" FT /db_xref="UniProtKB/TrEMBL:O69908" FT /protein_id="CAA19412.1" FT /translation="MYQRNTDALDVAMGVVERAVQPVRLRAVAYARVSTEEQAKGYGVQ FT AALKKILRYIGRKDWDHVGTYTDEGISGSLEAADREDLKRLMADAHRQPKPFDIVVVSE FT GRAIGRVGRAFWRWVWALEDIGIYVGVVEDDYDNSTPEGRKKMRRDADYAETEWETIRK FT RTQGGLQEKAEDGGWPGGQPPYGYEIACQGQKGKSHLVQCAAEVKTLRMAWAMVVEEKL FT NTREVAARLNALNRFTRSGVPWSHSNLRAKLLSESTINARVIFRNPNRAHAGHGAKFGE FT DGKPLHGETVIIKLKPIFEPGEVAALQVTLAQTSKGAGRPKPKPYPLSKRLFNEHTGCN FT SHHVGMARTSREGRWYRCTGLAAKYPGDPTCTCKMVDADAMESAVWGEVVSLLGDPDRL FT RAMAAEWVGMAAGDQVQHADRIADFDKQIANLDRAIASMATECVKAGLPAAAIAQASAA FT LLEERRQLADLRDEAAAWLEETEAAEQRARDLEALATAARTRLADMDPAEQGEVLALLD FT VKVTITGPVPKPKLGLTCSLAEWFKVAGRLVPSELTDDMWAAAEPVVKAWEPSNHKLRP FT GRLMLDAMFYKARTGCRWDDLPERFGPWKGIHSRYKTWRNCGVWDEIMAALPVDGPGYR FT PVPEINLVPPFRVEGRVDPRVLAGPDIQEEVVRPETGVPGPATSALSAGVHEMLRGDAV FT LVGDAAEVVELVGAMGELPPERRGPVLPTDLLESRTRQVLAGLPGRGTATAGEVALRAQ FT TTQDDAVARLYELRALGYVERHGDGWKLTRQAMISVRGGRSPC" FT misc_feature 137451..137933 FT /note="Pfam match to entry recombinase PF00239, FT Site-specific recombinases, score 36.16" FT misc_feature 137457..137483 FT /note="PS00397 Site-specific recombinases active site" FT CDS 140043..140885 FT /transl_table=11 FT /gene="SCO5621" FT /gene_synonym="SC2E1.38" FT /gene_synonym="whiG" FT /product="RNA polymerase sigma factor WhiG" FT /note="SC2E1.38, whiG, RNA polymerase sigma factor WhiG, FT len: 280 aa; identical to RPSW_STRCO RNA polymerase sigma FT factor WhiG (280 aa). Also highly similar to RPSD_BACSU RNA FT polymerase sigma-D factor (sigma-28) (254 aa)(E(): 0, 43.0% FT identity in 242 aa overlap) and FLIA_ECOLI RNA polymerase FT sigma factor for flagellar operon (sigma F) (239 aa)(E(): FT 0, 42.8% identity in 229 aa overlap). Contains PS00715 and FT PS00716 Sigma-70 factors family signatures 1 and 2, Pfam FT match to entry sigma70 PF00140, Sigma-70 factors, score FT 342.03 and probable helix-turn-helix motif at aa 245 to 266 FT (Score 1657, +4.83 SD)" FT /db_xref="GOA:P17211" FT /db_xref="HSSP:1KU3" FT /db_xref="InterPro:IPR007627" FT /db_xref="UniProtKB/Swiss-Prot:P17211" FT /protein_id="CAA19413.1" FT /translation="MPQHTSGSDRAAIPPAARDGGSVRPPAPSTLDELWRSYKTTGDER FT LREQLILHYSPLVKYVAGRVSVGLPPNVEQADFVSSGVFGLIDAIEKFDVDREIKFETY FT AITRIRGAMIDELRALDWIPRSVRQKARNVERAYATLEARLRRTPSESEVAVEMGIAVE FT DLHAVFSQLSLANVVALEELLHAGGEGGGRLSLMDTLEDTAADNPVEVAEDRELRRLLA FT RAINTLPEREKTVVTLYYYEGLTLAEIGNVLGVTESRVSQIHTKSVLQLRAKLAGFGR" FT misc_feature 140172..140861 FT /note="Pfam match to entry sigma70 PF00140, Sigma-70 FT factors, score 342.03" FT misc_feature 140271..140312 FT /note="PS00715 Sigma-70 factors family signature 1" FT misc_feature 140775..140855 FT /note="PS00716 Sigma-70 factors family signature 2" FT RBS 140995..140999 FT /note="possible RBS upstream of SC2E1.39" FT CDS 141014..141571 FT /transl_table=11 FT /gene="SCO5622" FT /gene_synonym="SC2E1.39" FT /product="putative transcriptional regulator" FT /note="SC2E1.39, possible transcriptional regulator, len: FT 185 aa; equivalent to Streptomyces roseosporus TR:P72569 FT (EMBL:U58281) tetR homologue WhiR (179 aa) (86.6% identity FT in 179 aa overlap) and similar to several putative FT transcriptional regulators of the tetR family e.g. FT TR:E1247678 putative transcriptional regulator SC10A5.11 FT (S.coelicolor) (198 aa), fasta scores; opt: 434 z-score: FT 720.5 E(): 6.8e-33, 41.5% identity in 171 aa overlap. FT Contains probable helix-turn-helix motif at aa 29 to 50 FT (Score 1618, +4.70 SD) and Pfam match to entry tetR FT PF00440, Bacterial regulatory proteins, tetR family, score FT 29.18" FT /db_xref="GOA:O69909" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:O69909" FT /protein_id="CAA19414.1" FT /translation="MAEHRSMQRAALLDAARSLLSDGGTEALTFPALAERTGLARSSVY FT EYFRSRAAVVEELCAVDFPVWAAEVEAAMERETAPDAKVEAYVRTQLDLVGDRRHRAVV FT AISASELDAGAREKIRAAHGGLIAMIVEALGEMGHGQPRLAAMLLQGVVDAAVRRIELG FT AAEEPGAITEAAVSMALRGVRG" FT misc_feature 141047..141187 FT /note="Pfam match to entry tetR PF00440, Bacterial FT regulatory proteins, tetR family, score 29.18" FT CDS complement(141525..142205) FT /transl_table=11 FT /gene="SCO5623" FT /gene_synonym="SC2E1.40c" FT /product="hypothetical protein SC2E1.40c" FT /note="SC2E1.40c, probable secreted protein, len: 226 aa; FT some similarity to two putative secreted M. tuberculosis FT proteins YX22_MYCTU MTCY274.22 (249 aa), fasta scores; opt: FT 315 z-score: 268.8 E(): 9.7e-08, 40.7% identity in 145 aa FT overlap (also upstream of rpsB) and Y0GK_MYCTU MTCY13D12.20 FT (407 aa), fasta scores; opt: 218 z-score: 176.1 E(): 0.014, FT 34.1% identity in 164 aa overlap. Contains probable FT N-terminal signal sequence." FT /db_xref="InterPro:IPR016047" FT /db_xref="UniProtKB/TrEMBL:O69910" FT /protein_id="CAA19415.1" FT /translation="MRARARVVVLSAVLAVLAVPTAQAGRAAGPPPPATAAAAGWALPY FT AVGPMGRVDPAVPPVARHWPVGTRPAVLRGWDPPANPYGPGHRGVDLAAGGGAPVRAVA FT AGRVSFAGPVGGRGVVSVELTGTGEPPLRTTFAPVDAAVRKGDEVAAGEPLGTVQPTGS FT HCTACLHWGLLRGEVYLNPLSLLPPWLLDAGPSRLLPVAGVPVPGRGGISPVRRATPWR FT PPPP" FT misc_feature complement(141570..145508) FT /note="overlap with cosmid 6A9 (unfinished)" FT RBS complement(142212..142215) FT /note="possible RBS upstream of SC2E1.40c" FT misc_feature 142303..144465 FT /note="97.4% match to AF034101 AF034101 Streptomyces FT coelicolor ribosomal protein S2 (rpsB) and elongation FT factor Ts (tsf) genes from 1 to 2154" FT RBS 142480..142485 FT /note="possible RBS upstream of rpsB" FT CDS 142494..143426 FT /transl_table=11 FT /gene="SCO5624" FT /gene_synonym="rpsB" FT /product="30S ribosomal protein S2" FT /note="SC2E1.41, rpsB, 30S ribosomal protein S2, len: 310 FT aa; almost identical to RS2_STRCO 30S ribosomal protein S2 FT (242 aa), E(): 0, 96.7% identity in 242 aa overlap and also FT highly similar to many others e.g. RS2_ECOLI 30S ribosomal FT protein S2 (240 aa), fasta scores; opt: 744 z-score: 950.7 FT E(): 0, 50.4% identity in 224 aa overlap. Contains PS00962 FT Ribosomal protein S2 signature 1 and PS00211 ABC FT transporters family signature (probably a false positive). FT Also contains Pfam matches to entry S2 PF00318, Ribosomal FT protein S2, score 304.89 and to entry 60s_ribosomal FT PF00428, 60s Acidic ribosomal protein, score 24.36. Note FT that this sequence is longer than RS2_STRCO due to a FT sequence difference around 235 aa. This sequence has a FT C-terminal extension not present in other rpsB. The M. FT tuberculosis protein also has a C-terminal extension but FT with a differentsequence. Our sequence has been checked, FT and is also confirmed by sequence from the overlapping FT cosmid 6A9." FT /db_xref="GOA:O31212" FT /db_xref="InterPro:IPR018130" FT /db_xref="UniProtKB/Swiss-Prot:O31212" FT /protein_id="CAA19416.1" FT /translation="MAVVTMRELLESGVHFGHQTRRWNPKMKRFIFTERNGIYIIDLLQ FT SLSYIDRAYEFVKETVAHGGTVMFVGTKKQAQEAIAEQATRVGMPYVNQRWLGGMLTNF FT STVYKRLQRLKELEQIDFEDVAASGLTKKELLVLSREKAKLEKTLGGIREMSKVPSAVW FT IVDTKKEHIAVGEARKLNIPVVAILDTNCDPDEVDYKIPGNDDAIRSVTLLTRVIADAV FT AEGLIARSGAAGGAKGDKAAGEPLAAWERDLLEGEKAEKKDDAEAAEKPAEAPAAEAPA FT AEAAEAPAAEAAPAEEPAAEAPAADAEQA" FT misc_feature 142509..142544 FT /note="PS00962 Ribosomal protein S2 signature 1" FT misc_feature 142518..143171 FT /note="Pfam match to entry S2 PF00318, Ribosomal protein FT S2, score 304.89" FT misc_feature 143007..143051 FT /note="PS00211 ABC transporters family signature" FT misc_feature 143286..143402 FT /note="Pfam match to entry 60s_ribosomal PF00428, 60s FT Acidic ribosomal protein, score 24.36" FT CDS 143521..144357 FT /transl_table=11 FT /gene="SCO5625" FT /gene_synonym="tsf" FT /product="elongation factor Ts" FT /note="SC2E1.42, tsf, elongation factor Ts, len: 278. FT Almost identical to EFTS_STRCO elongation factor TS (EF-TS) FT (276 aa), fasta scores; opt: 1695 z-score: 2425.0 E(): 0, FT 97.8% identity in 278 aa overlap and highly similar to many FT others e.g. EFTS_ECOLI (282 aa), fasta scores; opt: 321 FT z-score: 681.2 E(): 1e-30, 38.4% identity in 276 aa FT overlap. Contains PS01126 Elongation factor Ts signature 1" FT /db_xref="GOA:O31213" FT /db_xref="HSSP:1TFE" FT /db_xref="InterPro:IPR000449" FT /db_xref="UniProtKB/Swiss-Prot:O31213" FT /protein_id="CAA19417.1" FT /translation="MANYTAADVKKLRELTGAGMMDCKKALDEAEGNVEKAVEALRIKG FT QKGVAKREGRSAENGAVVSIIADDNTSGVLVELKCETDFVAKGEKFQNVATAIAEHVAK FT AAPADLEALLASEIEPGKTVQAYVDEANANLGEKIVLDRFAQFSGGFVTAYMHRTMPDL FT PPQIGVLVELDKPNAEIAKGVAQHIAAFAPKYLSKEDVPAEVVESERRVAEETTRAEGK FT PEAALPKIVEGRLNGFFKDATLLGQPYALDNKKSVQKVLEEAGVSLKRFSRIKVGI" FT misc_feature 143554..143601 FT /note="PS01126 Elongation factor Ts signature 1" FT RBS 144550..144553 FT /note="possible RBS upstream of pyrH" FT CDS 144563..145324 FT /transl_table=11 FT /gene="SCO5626" FT /gene_synonym="pyrH" FT /product="uridylate kinase" FT /note="SC2E1.43, pyrH, uridylate kinase, len: 253 aa; FT highly similar to many e.g. PYRH_ECOLI uridylate kinase (EC FT 2.7.4.-) (240 aa), fasta scores; opt: 668 z-score: 968.6 FT E(): 0, 45.9% identity in 233 aa overlap" FT /db_xref="GOA:O69913" FT /db_xref="InterPro:IPR015963" FT /db_xref="UniProtKB/Swiss-Prot:O69913" FT /protein_id="CAA19418.1" FT /translation="MSSTKAEKSDDGKVSGRFMLKLSGEAFSGGGGLGVDPDVVHAIAR FT EIAAVVRDGAQIAIVIGGGNFFRGAELQVRGMDRARSDYMGMLGTVMNCLALQDFLEKE FT GVDCRVQTAITMGQVAEPYIPLRAVRHLEKGRVVIFGAGMGMPYFSTDTTAAQRALEID FT AEALLMGKNGVDGVYDSDPKTNPDAVKFDALGYGEVITRDLKVADATAVTLCRDNSLPI FT VVFELLKEGNIARAVKGEKIGTLVGDQGSRD" FT misc_feature 145222..145508 FT /note="overlap with cosmid 2E1 from: 38676 to: 38962" FT RBS 145492..145496 FT /note="possible RBS upstream of frr" FT CDS 145503..146060 FT /transl_table=11 FT /gene="SCO5627" FT /gene_synonym="frr" FT /product="ribosome recycling factor" FT /note="SC6A9.40c, frr, ribosome recycling factor, len: 185 FT aa; highly similar to many e.g. RRF_ECOLI ribosome FT recycling factor (ribosome releasing factor) (185 aa), FT fasta scores; opt: 504 z-score: 841.1 E(): 0, 41.8% FT identity in 177 aa overlap" FT /db_xref="GOA:O86770" FT /db_xref="HSSP:1GE9" FT /db_xref="InterPro:IPR015998" FT /db_xref="UniProtKB/Swiss-Prot:O86770" FT /protein_id="CAA19925.1" FT /translation="MIEETLLEAEEKMEKAVVVAKEDFAAIRTGRAHPAMFNKIVAEYY FT GAPTPINQLASFSVPEPRMAVVTPFDKTALRNIEQAIRDSDLGVNPSNDGNIIRVTFPE FT LTEERRREYIKVAKAKGEDAKVSIRSVRRKAKDSIDKMVKDGEVGEDEGRRAEKELDDT FT TAKYVAQVDELLKHKEAELLEV" FT RBS 146052..146055 FT /note="possible RBS upstream of SC6A9.39c" FT CDS 146060..147235 FT /transl_table=11 FT /gene="SCO5628" FT /gene_synonym="SC6A9.39c" FT /product="putative integral membrane protein" FT /note="SC6A9.39c, probable integral membrane protein, len: FT 391 aa; C-terminus is similar to many phosphatidate FT cytidylyltransferases e.g. SW:CDSA_ECOLI (EMBL:M11330) FT phosphatidate cytidylyltransferase (249 aa), fasta scores; FT opt: 379 z-score: 384.3 E(): 3.6e-14, 38.8% identity in 196 FT aa overlap" FT /db_xref="GOA:O86769" FT /db_xref="InterPro:IPR000374" FT /db_xref="UniProtKB/TrEMBL:O86769" FT /protein_id="CAA19924.1" FT /translation="MNDSSWGAPPQAGYWGPSDQGPVQGAGPAGPAYDAHYAQQTRPMP FT IVPDVPEHGGDQDDDQGTARLSGPLFRDEPFHDQPPRDEPYRDQNPSAQPYAAVPQNPE FT PMPDAPQPAQSQPPPQKKSAGRDLGAAIGVGVGLGVVIIASLFVVKAVFVGVIAVAVVV FT GLWELTKRLEERKGIKAPLVPLAIGGAAMVVAGYARGAEGAWVAMALTALAVLVWRMTE FT PPEGYLKDVTAGLFAAFYVPFLATFVAMMLAADDGAWRVLVFLILTVVSDTGAYAVGWR FT FGRKKLAPRISPGKTREGLLGAIAFAMVAGALCMQFLIDDGAWWQGLLLGLVVAVSATL FT GDLGESMIKRDLGIKDMGTLLPGHGGIMDRLDSLLPTAPVVWLLLVIFVGS" FT CDS complement(147360..150020) FT /transl_table=11 FT /gene="SCO5629" FT /gene_synonym="SC6A9.38" FT /product="putative ATP /GTP-binding protein" FT /note="SC6A9.38, unknown ATP /GTP-binding protein, len: 886 FT aa; C-terminus contains 7 x 42 aa repeats with weak FT similarity to eukaryotic kinesin light chain 42 aa repeats FT e.g. KNLC_LOLPE kinesin light chain (klc) (571 aa), fasta FT scores; opt: 302 z-score: 260.7 E(): 2.8e-07, 24.0% FT identity in 405 aa overlap. Contains PS00017 ATP/GTP- FT binding" FT /db_xref="GOA:O86768" FT /db_xref="InterPro:IPR011990" FT /db_xref="UniProtKB/TrEMBL:O86768" FT /protein_id="CAA19923.1" FT /translation="MTDHAQQFFISYAGTDRAWAEWVGWHLEQAGHRVILDVWDWRTGD FT NLVQRMDEALERADAVIALFSTSYFEDERWTTEEWTAAVAHRDRLIPLALEPLTTSDLP FT RVLAAKLRKNLHGLDESAALTALREAVNSGSRPSVPPPFPGTVPAAGALPAAAPVPAAG FT RNRPRLPGSAEQPRVWSVRRRNPDFAGRETEIARLRESLMQESKAVPQALHGMGGVGKT FT QLALEYAHRFADQYDVVWWIDAEQPDEIPVHYTELAHRLGLAKPDAGAEANARALLSHL FT DTLDRWLLILDNAEDPAQVEPWLAQGPGHTLITSRNPNWAGTARATPLNVFTRTDSLTY FT LQGRVGGMDDEQADTLAADLGDLPLALAQAAGVIANGGVSLGLYHQLLATNTTRILERG FT GAPGYPAPVAATVTIAVDRLTDEHPDAIALLRLVALLGPEPIRNAWLESVRPRLTTIPG FT DSDDPMWLHEALSPLSRYGLARTEPESFQIHRLTQAVLRDQSLPDQSAAIRRDATALLS FT AANPGDPQSPGNWPGWAALTPHLTAQHLAPTEQPELRPTLLDAAHYLIRSGQTRTARDL FT TATAHAAWATDLGEDHPDTLTSAQFLGHATADLGEHAEARRIIEDTLTRRRRTLGDDHP FT HTLQSANDLANVLDNLGEHTESHRIIEDTLTRRRRTLGDDHPHTLQSAHNLAASLHHLG FT EHTEARRILEDTLTRQRRTLGDDHLDTLQSAHSIAASLHSLGEHTESVRMDQETLARLR FT RILGDDHPDTLQSAHNLAVTLHDLGEHTEARRIIEDTLTRQRRTLGDDHPHTLQSAHNL FT AVTLHSLRQYAAAAQLLDDVRNRLRRTLGDDHPDTVDATHSLAKALIAVGKPFAAQRLL FT APQKQKKSRSRRKRR" FT repeat_region complement(147455..148259) FT /note="7x 126 bp degnerate repeats" FT misc_feature complement(149355..149378) FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT repeat_region complement(150094..150165) FT /note="approx 4 x 19 bp degenerate repeats" FT repeat_region 150515..150536 FT /note="20 /22 bp inverted repeat at end of IS1648" FT repeat_region complement(150515..151471) FT /note="IS1648; identical to copy in cosmid 3C8. A possibly FT identical sequence is present in the S. coelicolor plasmid FT SCP2*, starting 0.4 kb clockwise from the unique EcoRI site FT (T. Kieser, personal communication)" FT CDS complement(join(150534..150992,150989..151414)) FT /pseudo FT /transl_table=11 FT /gene="SCO5630" FT /gene_synonym="SC6A9.37" FT /gene_synonym="SC6A9.36" FT /product="putative transposase" FT /note="SC6A9.37, probable IS1648 transposase, len: 152 aa; FT identical to SC3C8.16. Note that this CDS is probably FT expressed by frameshifting from the upstream ORF" FT /note="SC6A9.36, probable IS1648 transposase, len: 141 aa; FT identical to SC3C8.15. Note that this CDS is probably FT expressed by frameshifting into the downstream ORF" FT CDS complement(151437..151679) FT /transl_table=11 FT /gene="SCO5632" FT /gene_synonym="SC6A9.35" FT /product="hypothetical protein SC6A9.35" FT /note="SC6A9.35, unknown, len: 80 aa" FT /db_xref="UniProtKB/TrEMBL:O86767" FT /protein_id="CAA19920.1" FT /translation="MRPSTPDNGGNAAPSGDEEPTGAAYIKITTVPNGPSVMASVPEKE FT ATRMLETGEFAVGIGGTVIGPYAMARHCPADHVTF" FT repeat_region complement(151450..151471) FT /note="20 /22 bp inverted repeat at end of IS1648" FT misc_feature complement(151683..152683) FT /note="AT rich region: approx 60% GC" FT RBS complement(151686..151690) FT /note="possible RBS upstream of SC6A9.35" FT stem_loop complement(152439..152494) FT /note="hairpin loop with 25 bp stem" FT CDS complement(152491..154797) FT /transl_table=11 FT /gene="SCO5633" FT /gene_synonym="SC6A9.34" FT /product="traSA:integrase fusion protein" FT /note="SC6A9.34, probable fusion protein partially within FT putative integrated plasmid, len: 259 aa; N-terminus is FT almost identical to TR:E1286466 (EMBL:AJ005260) plasmid FT transfer protein traSA from Streptomyces ambofaciens FT plasmid pSAM2 (415 aa); 96.2% identity in 369 aa overlap, FT and similar to other members of the spoIIIE /ftsK family FT e.g. SPI_STRAZ sporulation-regulatory protein (303 aa), FT fasta scores; opt: 608 z-score: 904.0 E(): 0, 57.0% FT identity in 235 aa overlap. C-terminus is similar to many FT integrase /recombinase proteins e.g. TR:O55248 FT (EMBL:AF030986) Mycobacterium phage MS6 integrase (372 aa), FT fasta scores; opt: 184 z-score: 323.4 E(): 8.9e-11, 26.4% FT identity in 364 aa overlap. N-terminus contains TTA Leu FT codon; possible target for action of bldA and PS00017 ATP FT /GTP-binding= Pfam match to entry PF00589 Phage_integrase, FT Phage integrase family, score 40.60, E-value 3.5e-08" FT /db_xref="GOA:O86766" FT /db_xref="HSSP:1A0P" FT /db_xref="InterPro:IPR002104" FT /db_xref="UniProtKB/TrEMBL:O86766" FT /protein_id="CAA19919.1" FT /translation="MTWLMVAVVVVVAAAGLLRWRRPAWYWLTFGALVATVRILVRYAS FT VMEACGLTVPPSRWRLALARMTNRPAPESRPPRILRLRPTRTGLVLRLKLQPGQDAFDV FT AAATDRLRHSFGVYGVTSRELRSGVVEVRMTGYDVLQRVQMPAPAEPRPMRIPVALRED FT GAVHYRDYRAVPHGLTLGATESGKSVYQRNLVAGLAPHHVALVGIDCKQGVELFPLARR FT FSALADNPDTALDLLEALVGHMKDVYQLIRAEQRISVAVPDAEIAADIWDLREDLRAVP FT VVVLVDEVAELALFASKDEEKRRDRIITALVRLAQLGRAAGIYLEICGQRFGSELGKGI FT TMLRAQLTGRTAHRVNDETSADMAFGDLSPDAVLAAIQLPTDTPGIAVTGDSTGGWARI FT RAPHTTKSFPDRQKRLAELWLIEIASDMSRGRYVDPRAARVTFKGYAVKWLETHGIDPA FT SQVVVEQRLRLHAFRLIGSRPLDSFRPEHIRGLVSALENDPAVSGGYARNIYGDVRAVL FT SAAVDDGLLPRNPCSAKSVRPPAVEQRRVVPWLPEQVQAVRAALPQRYRPMVDMGAGCG FT LRQGEIVGLAEDAVDFASGIVRVLRQVKLIRGKAVFAPPKCNKERDVPLPPSVADALPA FT HMDAFKPVEITLPWRKPDGPKVSARLLFTNTASGLVWRSNFNVQEWKPALAAAGLISEA FT GADGKYESAREHGMHALRHFYASVLLDAGESIKAVSEYLGHADPGLTLRVYAHLMPSSQ FT ERTRSAIDQSLRFSG" FT misc_feature complement(152533..153195) FT /note="Pfam match to entry PF00589 Phage_integrase, Phage FT integrase family, score 40.60, E-value 3.5e-08" FT misc_feature complement(153584..156863) FT /note="Probable integrated plasmid; 95% identical to, but FT shorter than SAAJ5260 AJ005260 Streptomyces ambofaciens FT integrative element pSAM2 from 179 to 3471" FT misc_feature complement(154234..154257) FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT misc_feature complement(154552..154554) FT /note="TTA Leu codon; possible target for action of bldA" FT CDS complement(join(154800..154937,154945..155151)) FT /pseudo FT /transl_table=11 FT /gene="SCO5634" FT /gene_synonym="SC6A9.33" FT /gene_synonym="SC6A9.32" FT /product="hypothetical protein (pseudogene)" FT /note="SC6A9.33, unknown (pseudogene), len: 45 aa; almost FT identical to 3' end of TR:E1288124 (EMBL:AJ005260) Pra from FT Streptomyces ambofaciens plasmid pSAM2 (116 aa); 97.8% FT identity in 45 aa overlap. Similarity continues from FT SC6A9.31 after frameshift. No error in the cosmid sequence FT can be found to account for this" FT /note="SC6A9.32, unknown (pseudogene), len: 68 aa; FT identical to 5' end of TR:E1288124 (EMBL:AJ005260) Pra from FT Streptomyces ambofaciens plasmid pSAM2 (116 aa). Similarity FT continues in SC6A9.32 after frameshift. No error in the FT cosmid sequence can be found to account for this" FT RBS complement(155161..155165) FT /note="possible TRBS upstream of SC6A9.32" FT CDS complement(155289..156068) FT /transl_table=11 FT /gene="SCO5636" FT /gene_synonym="SC6A9.31" FT /gene_synonym="korSA" FT /product="transcriptional regulator" FT /note="SC6A9.31, korSA, transcriptional regulator, len: 259 FT aa; almost identical to TR:E1286465 (EMBL:AJ005260) KorSA FT from Streptomyces ambofaciens plasmid pSAM2 (259 aa); 98.5% FT identity in 259 aa overlap and similar to many members of FT the gntR family e.g. KORA_STRLI KorA protein (241 aa), FT fasta scores; opt: 187 z-score: 247.3 E(): 1.6e-06, 26.7% FT identity in 240 aa overlap. Contains Pfam match to entry FT PF00392 gntR, Bacterial regulatory proteins, gntR family, FT score 61.80, E-value 1.6e-17" FT /db_xref="GOA:O86763" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:O86763" FT /protein_id="CAA19916.1" FT /translation="MGTTVEGGRSGPRYVQVADEIVQQIRAGVLKPGDMVPSESEMVDR FT YGVSGGTIRKAMVEVRASGLVETRHGKGSIVKDRPPVRHRSSDRFRRSLRQGGKAAYLA FT ESEQSGATAKVSVLYIGPMEAPADAAQRLGVPAGTQVLARRRLYFRNGTPVETASSYLP FT WDVVKDIPELFAENPGGGGIYARLEDHGHEFAEFVETLQARPASKAEATELALSPGAPV FT VHLIREARTAAGLVVEVCDTLMAADQFVFEYRIPAAD" FT misc_feature complement(155841..156020) FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 61.80, E-value FT 1.6e-17" FT RBS complement(156081..156086) FT /note="possible RBS upstream of korSA" FT CDS 156156..156551 FT /transl_table=11 FT /gene="SCO5637" FT /gene_synonym="SC6A9.30c" FT /product="mutT-like protein" FT /note="SC6A9.30c, mutT-like protein, len: 131 aa; almost FT identical to TR:E1286464 (EMBL:AJ005260) ORF131 from FT Streptomyces ambofaciens plasmid pSAM2 (131 aa); 96.2% FT identity in 131 aa overlap, and similar to e.g. MUTT_PROVU FT mutator mutt protein FT (7,8-dihydro-8-oxoguanine-triphosphatase) (112 aa), fasta FT scores; opt: 128 z-score: 217.1 E(): 7.4e-05, 41.8% FT identity in 55 aa overlap. Contains PS00893 mutT domain FT signature and Pfam match to entry PF00293 mutT, Bacterial FT mutT protein, score 58.30, E-value 3e-15" FT /db_xref="GOA:O86762" FT /db_xref="HSSP:1K2E" FT /db_xref="InterPro:IPR020084" FT /db_xref="UniProtKB/TrEMBL:O86762" FT /protein_id="CAA19915.1" FT /translation="MVVREDGRLLAIRRADNGTWELPGGVLELDETPEAGVAREVWEET FT GIRVEVDELTGVYKNTTRGIVALVFRCKPSGGVERTSSESTAVSWLTPDEVSERMAEVY FT AIRLLDALDGAGPHVRSHDGRHLITVG" FT misc_feature 156180..156296 FT /note="Pfam match to entry PF00293 mutT, Bacterial mutT FT protein, score 58.30, E-value 3e-15" FT misc_feature 156228..156287 FT /note="PS00893 mutT domain signature" FT CDS complement(156881..157768) FT /transl_table=11 FT /gene="SCO5638" FT /gene_synonym="SC6A9.29" FT /product="integral membrane protein" FT /note="SC6A9.29, probable integral membrane protein, len: FT 295 aa; this ORF has atypically low GC bias in FramePlot" FT /db_xref="UniProtKB/TrEMBL:O86761" FT /protein_id="CAA19914.1" FT /translation="MISLTLQDEDFPELFRVADATSLNGQRLYLLGTRIRLSFAVLAAT FT LAVFSFQVGDKWDVAGLGVALAFLATLLVEIWLLVSRPERDWYDGRAFAESIKTLAWRY FT SVAATPFPNSEPSSLADQHFAAEIRKLVTEAPSDSIVVVSPVHITNKMSELRRAALEIR FT REAYLKGRIENQLKWYSDKSRFNVRMARRWRVALIAIEGLGIILAILKAGQTISIDAPG FT IAAAVLGAGSAWFAVRQYESLGRAYAFAANDLSTVYARLQHIIDENIWAQEVADAEEAI FT SREHTMWRASRGAS" FT misc_feature complement(156883..158883) FT /note="AT rich region: approx 53% GC" FT CDS complement(157765..158295) FT /transl_table=11 FT /gene="SCO5639" FT /gene_synonym="SC6A9.28" FT /product="hypothetical protein SC6A9.28" FT /note="SC6A9.28, unknown, len: 176 aa; this ORF has FT atypically low GC bias in FramePlot" FT /db_xref="InterPro:IPR015032" FT /db_xref="UniProtKB/TrEMBL:O86760" FT /protein_id="CAA19913.1" FT /translation="MEIAQVRRKCFISYHHEDEREVHQFIQKFDHVRDIFIARGIGAGM FT PGDVLNSNNRDYIMRRVRALYLGNSTVTIVMVGKCTWARRYVDWEIASTLRDDVRNKRG FT GLLGIVLPSAVNSPKAPPRLKDNLESGYAEWYHYPTSAAQLSRMIETAYSAREELKPKN FT DRLLFSYNRECRP" FT RBS complement(158302..158306) FT /note="possible RBS upstream of SC6A9.28" FT CDS complement(158402..158869) FT /transl_table=11 FT /gene="SCO5640" FT /gene_synonym="SC6A9.27" FT /product="hypothetical protein SC6A9.27" FT /note="SC6A9.27, unknown, len: 155 aa; this ORF has FT atypically low GC bias in FramePlot" FT /db_xref="UniProtKB/TrEMBL:O86759" FT /protein_id="CAA19912.1" FT /translation="MTREVEQVLADLEAWAGAVESNTPSFKSSLTAQQMRAVSVRVANQ FT LRDPSQKLHDSGVRFAETAEKADAVMNSIKDQISRVSDQEQRDALKAVVIPADRSTDLN FT EVANNMAELLDSMTSVEMMSAPLRKSLKPARIGITKIQDAARIVNRWLTDD" FT misc_feature complement(158789..158794) FT /note="DraI site: TTTAAA" FT RBS complement(158882..158886) FT /note="possible RBS upstream of SC6A9.27" FT repeat_region 158887..158914 FT /note="22 /27 bp inverted repeat at end of IS1649" FT CDS complement(158887..159843) FT /transl_table=11 FT /gene="SCO5641" FT /gene_synonym="SC6A9.26" FT /product="transposase" FT /note="SC6A9.26, probable transposase for IS1649, len: 318 FT aa; similar to many e.g. Corynebacterium striatum TR:O30997 FT (EMBL:AF024666) transposase TNP5564 (329 aa), fasta scores; FT opt: 589 z-score: 1572.9 E(): 0, 50.0% identity in 330 aa FT overlap. Contains probable helix-turn-helix motif at aa FT 26-47 (Score 1176, +3.19 SD)" FT /db_xref="GOA:O86758" FT /db_xref="InterPro:IPR001584" FT /db_xref="UniProtKB/TrEMBL:O86758" FT /protein_id="CAA19911.1" FT /translation="MVHRNAPLTETGRLRLARCVVEDGWPVRRAAERFQVSHTTASRWA FT RRYRQLGVTGMSDRSSRPHHQPRRTAAAVEEHVLRLRREHRIGPLRLAVRCGIAASTAH FT RILVRHGLPPLAALDRATGEPVRRYERARPGELVHIDVKKLGRIPDGGGHKTLGRAEGH FT RSRTNGAGWAYLHTALDDHSRIAYTEDLPDETAPTCAAFLVRATAYFASLGIRIERVLT FT DNAWAYSKNTWRNTCRDLDISPRWTRPWRPQTNGKVERFHRTLLDEWAYQKPYTSDHER FT REAFTHWLHWYNYHRPHTGIGGHTPASRGTNLSEQHS" FT repeat_region complement(158887..159956) FT /note="probable insertion element IS1649, inserted into FT AT-rich region" FT CDS complement(159819..160583) FT /transl_table=11 FT /gene="SCO5642" FT /gene_synonym="SC6A9.25" FT /product="hypothetical protein SC6A9.25" FT /note="SC6A9.25, unknown, len: 254 aa; this ORF has FT atypically low GC bias in FramePlot" FT /db_xref="GOA:O86757" FT /db_xref="InterPro:IPR000157" FT /db_xref="UniProtKB/TrEMBL:O86757" FT /protein_id="CAA19910.1" FT /translation="MEVLVNSRLAQENRLFISYAHADNDLFGDAVKSFAADLKGFYAVK FT TGDALSVFFDRESIGWGDNWRIEIDGELENASIFMPVITMQYFNRPACRDELNAFNQSA FT RRLGAQYLILPVVIAGAAAIRADHPIPEVATIAELQYRNLEDAFLAGKGTSEWRRALST FT LADELITLISRAEHAAPTLAPRDVANTGDMGLSPNDDSDFLSSIAELDVLSRDVGDTRA FT GFLKWVRASRFGVDCDISTEFRRPSWSTVMPR" FT RBS complement(159849..159854) FT /note="possible RBS upstream of SC6A9.26" FT misc_feature complement(159883..160683) FT /note="AT rich region: approx 55% GC" FT repeat_region complement(159929..159956) FT /note="22 /27 bp inverted repeat at end of IS1649" FT CDS complement(160650..161177) FT /transl_table=11 FT /gene="SCO5643" FT /gene_synonym="SC6A9.24" FT /product="hypothetical protein SC6A9.24" FT /note="SC6A9.24, questionable ORF, len: 175 aa; this ORF FT has atypically low GC bias in FramePlot" FT /db_xref="UniProtKB/TrEMBL:O86756" FT /protein_id="CAA19909.1" FT /translation="MALWAYLVPAAGQERAGVGRCGHALGGQPDRPRHGLGPLSAAIVA FT VSAAGTGAGHVVDTVTCRSADHPYADERPDEGDGCHQFGCPWASAAVGRRWVNHYRATD FT TRDSGRGHAGRLALCCEKAGRAKGVRRTPTSATLRRSTVLRRHRTGLLDALLPVRCFTV FT VDSVKTSVLRKS" FT RBS 161246..161250 FT /note="possible RBS upstream of SC6A9.23c" FT CDS 161261..161887 FT /transl_table=11 FT /gene="SCO5644" FT /gene_synonym="SC6A9.23c" FT /product="hypothetical protein SC6A9.23c" FT /note="SC6A9.23c, unknown, len: 208 aa; this ORF has FT atypically low GC bias in FramePlot" FT /db_xref="UniProtKB/TrEMBL:O86755" FT /protein_id="CAA19908.1" FT /translation="MSVLGSNCGEPSDWAVKRFGRHAGRLVETIPEQLGRAHARAHAVH FT LTARLKRRSPYGSTLAEAVRENLADTARELGGAVRDLRGYEYAVISDHALFPFKYANRL FT KPLERARLAADASPTRRRMLLSHGPEPEDGLFPLDDEYTTEEYEGLRETFEALGASTKL FT VCLFFTADPEGGIHVIHWGDARLEPDRTFTWLYSEQLRVATQSLE" FT CDS 162019..163125 FT /transl_table=11 FT /gene="SCO5645" FT /gene_synonym="SC6A9.22c" FT /product="conserved hypothetical protein SC6A9.22c" FT /note="SC6A9.22c, unknown, len: 368 aa; similar to FT hypothetical proteins from many organisms e.g. YLON_BACSU FT hypothetical 41.6 kd protein (363 aa), fasta scores; opt: FT 772 z-score: 1018.0 E(): 0, 39.2% identity in 342 aa FT overlap" FT /db_xref="GOA:O86754" FT /db_xref="InterPro:IPR007197" FT /db_xref="UniProtKB/Swiss-Prot:O86754" FT /protein_id="CAA19907.1" FT /translation="MPKPGELTFVAPRGVKKPPRHLADLTPAERKEAVAAIGEKPFRAK FT QLSQHYFARYAHAPEQWTDIPAGSREGLREALLPELMTVVRHLSTDQGTTRKTLWKLFD FT GTLVESVLMRYPDRVTMCISSQAGCGMNCPFCATGQAGLDRNLSTAEIVHQIVDGMRAL FT RDGEVPGGPARLSNIVFMGMGEPLANYNRVVGAIRRLTDPEPDGLGLSQRGITVSTVGL FT VPAIHRFTGEGFKCRLAISLHAPDDELRDTLVPVNTRWKVREVLDAGFEYAAKSGRRLS FT IEYALIRDINDQAWRGDRLGRLLRGRPVHVNLIPLNPTPGSKWTASRPEDEKAFVEAIA FT AHGVPVTIRDTRGQEIDGACGQLAASER" FT RBS 163337..163342 FT /note="possible RBS upstream of SC6A9.21c" FT CDS 163349..164470 FT /transl_table=11 FT /gene="SCO5646" FT /gene_synonym="SC6A9.21c" FT /product="putative solute binding lipoprotein" FT /note="SC6A9.21c, probable solute binding lipoprotein, len: FT 373 aa; similar to e.g. TBPA_ECOLI thiamin-binding FT periplasmic protein (327 aa), fasta scores; opt: 220 FT z-score: 423.3 E(): 2.4e-16, 28.4% identity in 327 aa FT overlap. Contains N-terminla signal sequence and FT appropriately positioned PS00013 Prokaryotic membrane FT lipoprotein lipid attachment site" FT /db_xref="GOA:O86753" FT /db_xref="InterPro:IPR005948" FT /db_xref="UniProtKB/TrEMBL:O86753" FT /protein_id="CAA19906.1" FT /translation="MSITKRGTTRKGITTKAGVLAVGLGMVGTLAACGSSDDGGDGSGS FT GGSRTVTLVSHDSWAVSKDVIAAFEKNSGYKVKVLEDGDAGQAVNKAILTKDNPQGDVF FT FGVDNTLLSRALDNGLFQSYEAKGSDLVLPEYRADREKHRVTPVDTGDICVNYDKAYFR FT EHGLTPPRTLDDLVKPEYKDLLVTENAGSSSPGLGFLLGTAAKYGDEGWEGYWKKLKSN FT GVKVVDSWEQAYNEEFSGSAGGKKAKGDRPLVVSYASSPPVEVVYADPQPDTAPTGVAD FT GTCFRQVEYAGLLSNAKNPEGGKALLDFLLSKSFQEDMPLNMFVYPVREGAQVPEVFSK FT FGPRAKDPQTLDPAKIADNRDQWVKSWTSLVLK" FT misc_feature 163415..163447 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS 164467..166128 FT /transl_table=11 FT /gene="SCO5647" FT /gene_synonym="SC6A9.20c" FT /product="ABC transporter integral membrane protein" FT /note="SC6A9.20c, probable ABC transporter integral FT membrane protein, len: 553 aa; similar to many e.g. FT Y4FN_RHISN probable ABC transporter permease protein (569 FT aa), fasta scores; opt: 296 z-score: 555.5 E(): 1e-23, FT 25.4% identity in 563 aa overlap. Contains 2x Pfam match to FT entry PF00528 BPD_transp, Binding-protein-dependent FT transport systems inner membrane component, scores 40.70, FT E-value 3.2e-08 and 46.50, E-value 6.1e-10" FT /db_xref="GOA:O86752" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:O86752" FT /protein_id="CAA19905.1" FT /translation="MTRAGKRARAVRGSAARLGLMAVPVAFFAVFFAYPVAAIVARGLK FT TDGVWQLGRIGDVLAQSDVRHVLWFTTWQALASTGLTLLVALPGAYVFARFDFPGKQVL FT RAVVTVPFVLPTVVVGTAFLALVGRGGLFDELWGLRLDTTVWAILLAHVFFNYAVVVRT FT VGGLWAQLDPRQEEAARMLGASRLRAWRQVTLPALAPAVAAAALMVFLFTFTSFGVVQI FT LGGPTFSTLEVEIYRQTSQVFDLSTAAVLTLIQFAAVVAVLAVHAWTVRRRETALRLVD FT AATTARRPRGAGQWALLAGVLGVIAVLLVLPLAVLVQRSLGASGFGYYRALTREDGGAF FT LVPPIEAIGNSLQYAVAATAIAVVIGALAATALTRRDAGRFVRGFDALLMLPLGVSAVT FT VGFGFLIALDEPPLDLRSSWILVPLAQALVGVPFVVRTMLPVLRAVDGRLREAAAVLGA FT SPWRVWREVDLPMVRRALLVAAGFAFAVSLGEFGATVFIARPDNPTLPVAVARLLGRPG FT DMNYGQAMALSTILMLVCAVALVVLERLRTDRSGEF" FT misc_feature 164965..165186 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 46.50, E-value 6.1e-10" FT misc_feature 165787..166008 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 40.70, E-value 3.2e-08" FT RBS 166119..166122 FT /note="possible RBS upstream of SC6A9.19c" FT CDS 166131..167177 FT /transl_table=11 FT /gene="SCO5648" FT /gene_synonym="SC6A9.19c" FT /product="ABC transporter ATP binding protein" FT /note="SC6A9.19c, probable ABC transporter ATP binding FT protein, len: 348 aa; similar to many e.g. POTA_ECOLI FT spermidine /putrescine transport ATP-binding protein (378 FT aa), fasta scores; opt: 715 z-score: 832.8 E(): 0, 42.5% FT identity in 308 aa overlap. Contains PS00017 ATP FT /GTP-binding= transporters family signature and Pfam match FT to entry PF00005 ABC_tran, ABC transporters, score 226.00, FT E-value 5.5e-64" FT /db_xref="GOA:O86751" FT /db_xref="HSSP:1Q1B" FT /db_xref="InterPro:IPR013611" FT /db_xref="UniProtKB/Swiss-Prot:O86751" FT /protein_id="CAA19904.1" FT /translation="MPPSLLSLEGATVRFGGRAVLDDVGLGVAEHEVVCVLGPSGSGKS FT TLLRAVAGLQPLDAGRVTLDGRDQSGVPAHKREVGLMFQDHQLFPQRDVAGNIAFGPRM FT RGASRAEQQARVAELLQLVGLPGAARRSVAALSGGEQQRVALARALAPRPRLLMLDEPL FT GQLDRSLRERLVVELRELFGRLGTTVLAVTHDQGEAFALADRVVVMRDGRIAQSGTPLE FT VWQRPADAFVARFLGFENVAEASVAGQAADTPWGKVPVPEDAPQGTRTVLVRPAGVRVV FT PADEGLRCTVTARTFRGTHVAVHLQPEGAPRLEAACALRAAPEVGAAVGVEFDAADVVV FT LGGSGVPE" FT misc_feature 166221..166766 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporters, score 226.00, E-value 5.5e-64" FT misc_feature 166242..166265 FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT misc_feature 166536..166580 FT /note="PS00211 ABC transporters family signature" FT CDS 167202..168002 FT /transl_table=11 FT /gene="SCO5649" FT /gene_synonym="SC6A9.18c" FT /product="conserved hypothetical protein" FT /note="SC6A9.18c, unknown, len: 266 aa; similar to M. FT tuberculosis hypothetical protein TR:O07256 (EMBL:Z96800) FT MTCY63.37 (261 aa), fasta scores; opt: 508 z-score: 606.3 FT E(): 1.6e-26, 36.7% identity in 251 aa overlap" FT /db_xref="InterPro:IPR010872" FT /db_xref="UniProtKB/TrEMBL:O86750" FT /protein_id="CAA19903.1" FT /translation="MTLLAHDRYCEEIVHQVGRLRAVVTSGAELTATVPTCPDWTLEDL FT VRHVGRALRWTGLIVGTRAEQDVPVDRAPGAGGPAASGDAAALDAWLAESGEVVVGALR FT EAGPDARAWSWAGVGTAGFWARRMTHELVVHGADAALAAGLPHRAVAPEVAADAIDEWL FT DIVRFVQRALPGAAANELRAPGSSLHLHATDTAAELNAEWIVELPDDGITWRRGHEKAT FT VALRGPLTDVLLAFYGRLSPDAPGLEVLGDRKLLELWLEKATFG" FT CDS complement(168064..168768) FT /transl_table=11 FT /gene="SCO5650" FT /gene_synonym="SC6A9.17" FT /product="putative membrane protein" FT /note="SC6A9.17, possible membrane protein, len: 234 aa. FT Contains possible hydrpphobic membrane spanning regions" FT /db_xref="InterPro:IPR019931" FT /db_xref="UniProtKB/TrEMBL:O86749" FT /protein_id="CAA19902.1" FT /translation="MAVLSIISRTASRRGVRALGVVAASAALALSASGNALACNISEFS FT AEAKCDGDNGVITVTDVDPAGIPATVTVYLKDGDKQVGQQTVKGSKDGTTVSFPVDWQP FT NTTYRVHVKADRYVDEDIQPDVTTPSTPCKTEDTPTPTPSESSSTPSDETESPAPEPST FT SAPAPSQSESTAPAAVPNDNAPSPAAGDSNLAETGANSNTGMIAGIAAALVVVGGGAVF FT FGLRRRGANSNS" FT RBS complement(168774..168778) FT /note="possible RBS upstream of SC6A9.17" FT CDS complement(168925..170109) FT /transl_table=11 FT /gene="SCO5651" FT /gene_synonym="SC6A9.16" FT /product="hypothetical protein SC6A9.16" FT /note="SC6A9.16, unknown, len: 394 aa" FT /db_xref="UniProtKB/TrEMBL:O86748" FT /protein_id="CAA19901.1" FT /translation="MDQTPDQTPAQRRARSPHGSPSLSQFQSHHASHDREIESLDEFDR FT VVSSPGSLAHHRVQAVDLTDRTEALLAADPTGAVFLGCPMEPGAAAGVRAAGALVFPPI FT PGLPFDPYRGRVYSPDELYARLGEGYEATPDALAYDWFQQTRADGDVFASMLRAIHDDA FT VSDALDELVVGSRVVGVMGGHAMARGTAEYAGAARLGRELTRAGLTVATGGGPGAMEAA FT NLGAYAAPFDDRMLDEALMLLAKVPSFAPSIADWARSAFEVRERWPGGGASIGIPTWFY FT GHEPPNAFAAHIAKYFANATREDGLLARSTAGVVFLPGAAGTLQEIFDNATPNYYESRG FT EPTPMVLVDRRHWTETLPAWPLLRSLAKGRTMESRIALVDRIDEAPEALKRVGG" FT CDS complement(170136..170543) FT /transl_table=11 FT /gene="SCO5652" FT /gene_synonym="SC6A9.15" FT /product="conserved hypothetical protein SC6A9.15" FT /note="SC6A9.15, conserved hypothetical protein, len: 135 FT aa; similar to TR:Q98D71 (EMBL:AP003005) hypothetical FT protein from Rhizobium loti (134 aa) fasta scores; opt: FT 401, Z-score: 482.3, E(): 3.1e-19, 46.212% identity FT (46.565% ungapped) in 132 aa overlap." FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/TrEMBL:O86747" FT /protein_id="CAA19900.1" FT /translation="MYQQMIFVNLATNDLDAAKKFFAGLGWELNAQFSDDSTASFPVSD FT TIVVMVHTPQKYREFTKKEIADSAKTSEVLIALSAESREKVDELVEKAVAAGGSVSGET FT QDHGFMYGRAFDDVDGHTFEVVWMDPAAVQG" FT RBS complement(170548..170551) FT /note="possible RBS upstream of SC6A9.15" FT CDS complement(170649..172109) FT /transl_table=11 FT /gene="SCO5653" FT /gene_synonym="SC6A9.14" FT /product="putative integral membrane protein" FT /note="SC6A9.14, probable integral membrane protein, len: FT 486 aa; contains Pro- Ala- rich central region" FT /db_xref="UniProtKB/TrEMBL:O86746" FT /protein_id="CAA19899.1" FT /translation="MLALRLTRTAHLAVHLRRLLVALASAGTGFLLLCALGHALSHPDA FT PGASALRLAWCAAPLAAAVYLAVAVARTDPGTRPRSGLSAIGLGPGRLMAVSATTTALS FT AALGSVAALLAFLYLRGSLTGRPPSDRVAADALAVGQSLPAPAVLTLLVLVPALASASV FT AHTLRPRDPRPAAAAAPRGYGRFGAYGWGKARETFGAYGRFGARLAVTAGSRAAAGPAG FT SRAAGAARVGAGGALLTQASDPHPPAPTDGTTQTLDAAPPAPAPAPTDATSQTPDATPA FT AHPEPTPRPQNTTALPWGIAVLTAGLTVETYTGNAAGAPAPGTAPSAGVLIGWALTALG FT LALAGPGLTHLCGRLLQAARPGALRLLAGRVLMEEAQRVGRPLGVVAAVAAAAYVATTV FT YDGDGPAFGPLTTLGALLVAGCTVATLLTAAVEARDARADTTDALLRLGAPPATLRAAA FT AVRAAALLVLFGPLVLIVAVLAALPLDH" FT CDS complement(172091..172867) FT /transl_table=11 FT /gene="SCO5654" FT /gene_synonym="SC6A9.13" FT /product="ABC transporter ATP-binding protein" FT /note="SC6A9.13, probable ABC transporter ATP-binding FT protein, len: 258 aa; similar to many e.g. YBBA_ECOLI FT hypothetical ABC transporter ATP-binding protein (228 aa), FT fasta scores; opt: 462 z-score: 578.7 E(): 5.3e-25, 40.4% FT identity in 198 aa overlap. Contains PS00017 ATP FT /GTP-binding= PF00005 ABC_tran, ABC transporters, score FT 173.20, E-value 4.2e-48" FT /db_xref="GOA:O86745" FT /db_xref="HSSP:1F3O" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:O86745" FT /protein_id="CAA19898.1" FT /translation="MEAPPDNDVLWARALHFQHHDGSPALQGVSLGVREGEILAVSGPR FT GSGKTTLLRCLSGLVKPQDGEVWFNSVPVHTMGPLGRERLRRDRFGWIDPAPALVPELN FT AWENAALPLMLRGTGRRRAKTAALEWLDRLDVGGKARRRPHELQQAERQRVCIARALAV FT TPAVLFADEPTAPLHRADRAHVLRTLTTAARSHGITVLLATHDAQTAALADRAVALLDG FT RRVRTVHLPPLAETTVATGATGTPGTEGRAACSLSA" FT misc_feature complement(172202..172762) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporters, score 173.20, E-value 4.2e-48" FT misc_feature complement(172718..172741) FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT RBS complement(172876..172880) FT /note="possible RBS upstream of SC6A9.13" FT CDS complement(173073..174446) FT /transl_table=11 FT /gene="SCO5655" FT /gene_synonym="SC6A9.12" FT /product="putative aminotransferase" FT /note="SC6A9.12, probable aminotransferase, len: 457 aa; FT similar to many e.g. BIOA_BACSU FT adenosylmethionine-8-amino-7-oxononanoate aminotransferase FT (448 aa), fasta scores; opt: 895 z-score: 881.6 E(): 0, FT 35.6% identity in 449 aa overlap. Also highly similar to M. FT tuberculosis putative aminotransferase TR:O53379 FT (EMBL:AL021841) MTV016.29; 70.3% identity in 438 aa FT overlap. Contains Pfam match to entry PF00202 aminotran_3, FT Aminotransferases class-III pyridoxal-phosphate, score FT 355.70, E-value 3.5e-123" FT /db_xref="GOA:O86744" FT /db_xref="HSSP:1QJ3" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:O86744" FT /protein_id="CAA19897.1" FT /translation="MSTDSPKDLSRTAYDHLWMHFTRMSSYENAPVPTIVRGEGTHIYD FT DKGRRYLDGLAGLFVVQAGHGRQELAETASKQAQELAFFPVWSYAHPKAVELAERLANE FT APGDLNKVFFTTGGGEAVETAWKLAKQYFKLTGKPTKYKVISRAVAYHGTPQGALSITG FT LPALKAPFEPLVPGAHKVPNTNIYRAPIHGDDPEAYGRWAADQIEQQILFEGPETVAAV FT FLEPVQNAGGCFPPPPGYFQRVREICDQYDVLLVSDEVICAFGRLGTTFACDKFGYVPD FT MITCAKGMTSGYSPIGACVISDRLAEPFYKGDNTFLHGYTFGGHPVSAAVGIANLDLFE FT REGLNQHVLDNEGAFRATLEKLHDLPIVGDVRGNGFFYGIELVKDKATKESFDEEETER FT VLYGFLSKKLFENGLYCRADDRGDPVIQLAPPLISNQETFDEIEQILRATLTEAWTKL" FT misc_feature complement(173151..174329) FT /note="Pfam match to entry PF00202 aminotran_3, FT Aminotransferases class-III pyridoxal-phosphate, score FT 355.70, E-value 3.5e-123" FT CDS complement(174449..174949) FT /transl_table=11 FT /gene="SCO5656" FT /gene_synonym="SC6A9.11" FT /product="transcriptional regulatory protein" FT /note="SC6A9.11, probable transcriptional regulatory FT protein, len: 166 aa; similar to many members of the asnC FT family e.g. LRP_ECOLI leucine-responsive regulatory protein FT (164 aa), fasta scores; opt: 190 z-score: 294.3 E(): FT 3.7e-09, 27.6% identity in 156 aa overlap. Contains PS00519 FT Bacterial regulatory proteins, asnC family signature and FT probable helix-turn-helix motif at aa 39-60 (Score 1545, FT +4.45 SD)" FT /db_xref="GOA:O86743" FT /db_xref="InterPro:IPR019888" FT /db_xref="UniProtKB/TrEMBL:O86743" FT /protein_id="CAA19896.1" FT /translation="MASRSADQKDSRESRNGGPQLDAVSLAIIEQLQEDGRRPYAAIGK FT AVGLSEAAVRQRVQKLLDQGVMQIVAVTDPLTVGFRRQAMVGVNVEGDVESVAEALSAM FT SECEYVVMTAGSFDLMVEVVCEDDDHLLEVINRRIRAVPGVRSTESFVYMKLKKQTYMW FT GTR" FT misc_feature complement(174755..174835) FT /note="PS00519 Bacterial regulatory proteins, asnC family FT signature" FT RBS 175118..175122 FT /note="possible RBS upstream of SC6A9.10c" FT CDS 175130..176569 FT /transl_table=11 FT /gene="SCO5657" FT /gene_synonym="SC6A9.10c" FT /product="aldehyde dehydrogenase" FT /note="SC6A9.10c, probable aldehyde dehydrogenase, len: 479 FT aa; similar to many e.g. DHAB_BACSU betaine aldehyde FT dehydrogenase (EC 1.2.1.8) (490 aa), fasta scores; opt: FT 1131 z-score: 1242.7 E(): 0, 39.2% identity in 472 aa FT overlap. Contains PS00687 Aldehyde dehydrogenases glutamic FT acid active site, PS00070 Aldehyde dehydrogenases cysteine FT active site and Pfam match to entry PF00171 aldedh, FT Aldehyde dehydrogenases, score 598.80, E-value 3.2e-176" FT /db_xref="GOA:O86742" FT /db_xref="HSSP:1BXS" FT /db_xref="InterPro:IPR016162" FT /db_xref="UniProtKB/TrEMBL:O86742" FT /protein_id="CAA19895.1" FT /translation="MSTELRRLRNYIDGEFRDAADGRTTEVVNPATGEAYATAPLSGQA FT DVDAAMAAAAAAFPAWRDLVPAERQKALLKIADAFEERAEELIAAEVENTGKPIGLTRS FT EEIPPMVDQIRFFAGAARMLEGRGAGEYMEGLTSFVRREPIGVCAQVAPWNYPMMMAVW FT KFAPALAAGNTVVLKPSDTTPASTALMADIIGSIVPKGVFNVVCGDRDTGRLMVEHETP FT AMASITGSVRAGMSVAESASKDLKRVHLELGGKAPVVVFEDTDIPKAVEGISEAGYFNA FT GQDCTAATRVLVHESVHDEFVSALAKAASEIKTGQPDDEDVMYGPLNNPNQLKQVSGFI FT ERLPAHAKVEAGGHRVGDKGYFYAPTVVSGLKQDDEIIQREVFGPVITVQAFRDEDQAV FT EWANGVEYALASSVWTKDHGRAMRMSKKLDFGCVWINTHIPLVAEMPHGGFKKSGYGKD FT LSGYGFEDYTRIKHVMTSLDM" FT misc_feature 175172..176560 FT /note="Pfam match to entry PF00171 aldedh, Aldehyde FT dehydrogenases, score 598.80, E-value 3.2e-176" FT misc_feature 175877..175900 FT /note="PS00687 Aldehyde dehydrogenases glutamic acid active FT site" FT misc_feature 175961..175996 FT /note="PS00070 Aldehyde dehydrogenases cysteine active FT site" FT CDS 176741..177940 FT /transl_table=11 FT /gene="SCO5658" FT /gene_synonym="SC6A9.09c" FT /product="putative polyamine-binding lipoprotein" FT /note="SC6A9.09c, possible polyamine-binding lipoprotein, FT len: 399 aa; some similarity to several spermidine FT /putrescine /putrescine-binding= scores; opt: 389 z-score: FT 352.1 E(): 2.2e-12, 26.9% identity in 349 aa overlap. FT Contains N-terminal siganl sequence and appropriately FT positioned PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT /db_xref="GOA:O86741" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:O86741" FT /protein_id="CAA19894.1" FT /translation="MPLLPKTPSPSRRTLLRGLGGSAALGALGTLAGCGVPAAYVAPGD FT RAATDRSATERRLIWANWPLYIDTDDRHPSRRPTLEAFEKETGLSVDYIEEINDNDEFF FT GKISPSLMNHQPTDRDLIVISDWMCGRFVRLGWVQEMDRSRQPNVTKYLDPLLRSPAFD FT PGRKFTVPWQSGITGIAYNRHRLGREIRHVSDLWAADLKGRVTLLSGMDEAFALLMQGN FT GVDITDWKTDDFHRICDQVEKQVAKGQIRRFTGNDYIKDLSSGDVLACQAYSGDVIQLQ FT ADDPDIEFVVPEEGAELWAESLMIPDLARHKANAERLIDHYYRPEVAAELAAWVNYVCP FT VPAARDVLASSDDEETAALAEDPLIFPDAAMRERLAIARDISAGERTEFAKRWNGIVGV FT " FT misc_feature 176810..176842 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS 177953..178492 FT /transl_table=11 FT /gene="SCO5659" FT /gene_synonym="SC6A9.08c" FT /product="putative integral membrane protein" FT /note="SC6A9.08c, possible integral membrane protein, len: FT 179 aa; contains four possible transmembrane domains" FT /db_xref="UniProtKB/TrEMBL:O86740" FT /protein_id="CAA19893.1" FT /translation="MKNSSGDEAVGGAVTLGLLAAWALHDLEELATVPGWWRRNLPALR FT ERYPGMPEAVWRRAGSVNGREFAVAVGAMAAVVASASVAGRLTGGRSATYQTALHAFGL FT HGLVHLAQAGLVRGYTPGVATSPLIVVPFTLWARHRLRRAGVLRATRPRDLAVGLGFAG FT AATVGAHAVARRLTKA" FT CDS complement(178509..179669) FT /transl_table=11 FT /gene="SCO5660" FT /gene_synonym="SC6A9.07" FT /product="putative secreted peptidase" FT /note="SC6A9.07, probable secreted peptidase, len: 386 aa; FT similar to e.g. DAC_STRSQ D-alanyl-D-alanine FT carboxypeptidase precursor (406 aa), fasta scores; oopt: FT 544 z-score: 500.9 E(): 1.2e-20, 33.2% identity in 365 aa FT overlap. Contains N-terminal signal sequence and PS00017 FT ATP /GTP-binding site motif A (P-loop)" FT /db_xref="HSSP:3PTE" FT /db_xref="InterPro:IPR001466" FT /db_xref="UniProtKB/TrEMBL:O86739" FT /protein_id="CAA19892.1" FT /translation="MRARSHAVLAASVVLALAAGPLAAPAFAAPPAPASRSADQRGPDE FT EALRAAVAGLPNQYATAALVRVGTPGGDWHGSAGVRDLASGRPAHPDARFRAGSITKVV FT TAATVLRLAAQDEIDLDAPVQGYLPDLFTPDFEQPVSVRHLLNHTSGIKPGDGLGDDFA FT ELYSHRYETLTPQQVAASAIAKGPEDFVPGTRQQYLNINYTILGLLIEKVTGRSYASEA FT TRLVLRPAGMHHTYFPGTDPRIRGPHNRGYQAVERPDGTTRLVDVTEWNQADRWAAGDM FT ISTTADLERLLTKLFRGKIVPQPELEEMFTTPAGVPGAVRSAGLECREVGGQVFWGKSG FT SRYGYSAVVAGTRDLSRTLVYSVNSTDAKSAGPKPVADAIAAAALQ" FT misc_feature complement(178653..178676) FT /note="PS00017 ATP /GTP-binding site motif A (P-loop)" FT RBS complement(179676..179679) FT /note="possible RBS upstream of SC6A9.07" FT CDS complement(179823..180548) FT /transl_table=11 FT /gene="SCO5661" FT /gene_synonym="SC6A9.06" FT /product="hypothetical protein SC6A9.06" FT /note="SC6A9.06, unknown, len: 241 aa; similar to FT hypothetical proteins e.g. Bacillus subtilis TR:O07592 FT (EMBL:Y14082) YhdW (243 aa), fasta SCORES; opt: 144 FT z-score: 267.8 E(): 1.1e-07, 25.0% identity in 236 aa FT overlap" FT /db_xref="GOA:O86738" FT /db_xref="InterPro:IPR017946" FT /db_xref="UniProtKB/TrEMBL:O86738" FT /protein_id="CAA19891.1" FT /translation="MPPTMDTPRALTAVAHRGDPYRHRENTLDSLRSALERGADAVETD FT VRLTRDGVPVLLHDETLKRLWQHDRPLRSLSAEEVRGLTAGGVPTLAEALAATDGARLM FT LDLPGGPGERAVRRVVDVVRECGARDRVYYTAGAATMLAVRAADPAAEIAMTWTTAAPP FT RAGLLAAVRPRWLNYRFGLVDRALAERVHRDGFLLSVWTPDTRRTMRRLRAAGVDSITT FT NRIDVLCALRDANAAVPVP" FT CDS complement(180552..181715) FT /transl_table=11 FT /gene="SCO5662" FT /gene_synonym="SC6A9.05" FT /product="putative adenosine deaminase" FT /note="SC6A9.05, possible adenosine deaminase, len: 387 aa; FT similar to many e.g. ADD_ECOLI adenosine deaminase (EC FT 3.5.4.4) (333 aa), fasta SCORES; opt: 520 z-score: 510.9 FT E(): 3.2e-21, 31.3% identity in 335 aa overlap" FT /db_xref="GOA:O86737" FT /db_xref="InterPro:IPR006330" FT /db_xref="UniProtKB/Swiss-Prot:O86737" FT /protein_id="CAA19890.1" FT /translation="MRPAYDDPRTTDQPITRARPPPRAARGRRLGEEPLTEHLVDPDVP FT RDLHAFIAGLPKAELHVHHVGSASPRIVSELAARHADSKVPTDPEALVDYFTFTDFAHF FT IDVYLSVVDLIRTPEDVRLLTYEVARDMARQQVRYAELTITPFSSTRRGIDEGAFMDAI FT EDARKAAEAEFGTVLRWCFDIPGEAGLESAEETARLATDDRLRPEGLVSFGLGGPEIGV FT ARPQFKPYFDRAIAAGLHSVPHAGETTGPQTVWEALIDLRAERIGHGTSSAQDPKLLAH FT LAERRIPLEVCPTSNIATRAVRTLDEHPIKEFVRAGVPVTINSDDPPMFGTDLNNEYAV FT AARLLGLDERGLADLAKNGVEASFLDAPGKARIADEIDTYTAAWLAS" FT RBS 181767..181770 FT /note="possible RBS upstream of SC3A9.04c" FT CDS 181772..182452 FT /transl_table=11 FT /gene="SCO5663" FT /gene_synonym="SC3A9.04c" FT /product="putative integral membrane protein" FT /note="SC3A9.04c, probable integral membrane protein, len: FT 226 aa; has highly proline-rich N-terminus and two possible FT transmembrane domains in the C-terminus. Similar to FT downstream ORF SC3A9.03c, fasta scores; E(): 6.5e-06, 41.0% FT identity in 134 aa overlap" FT /db_xref="UniProtKB/TrEMBL:O86736" FT /protein_id="CAA19889.1" FT /translation="MTDAIRPEGEPSGGHDPWAPPESGPSLDKGPAADAGQPQQPPRQS FT QPPASDAPPPWQPPPGVHDQATVTSMPGAGFTGPESAVPPPPLAPGGAGVPGGYGYPGY FT GQGYGWPGMRTPPQNGLGTASMVLGILACALFCLYGVVSLVLGVLAVVFGIKGRRKAES FT GLADNHGQAQAGFVMGIVGIVLGVAVIVLIAIGITAAINEDSDGYDPYYGSARPVPVAV FT TAES" FT CDS 182511..182960 FT /transl_table=11 FT /gene="SCO5664" FT /gene_synonym="SC3A9.03c" FT /product="putative integral membrane protein" FT /note="SC3A9.03c, probable integral membrane protein, len: FT 149 aa; has Pro-, Gly-rich N-terminus and two possible FT transmembrane domains in the C-terminus; some similarity to FT M. tuberculosis hypothetical protein TR:E1264549 FT (EMBL:AL022121) MTV025.037 (451 aa), fasta scores; opt: 183 FT z-score: 182.2 E(): 0.0066, 33.1% identity in 145 aa FT overlap. Also similar to upstream gene SC3A9.04c, fasta FT scores; E(): 1.5e-06, 41.0% identity in 134 aa overlap" FT /db_xref="UniProtKB/TrEMBL:O86735" FT /protein_id="CAA19888.1" FT /translation="MSYSNPGPGDYGPPPQPGQPPAGGYAYPQSAPGYGYPNQGAAYQA FT APPVGYPQGPGYGMPMQPSNGMGTTGLVLGIIGVVCSLTFFLWFFGVILGILGIIFGAI FT GRGKATRGEATNKGSATAGLVLGITATVILPLLGFLAFASLMSVA" FT CDS complement(183022..183663) FT /transl_table=11 FT /gene="SCO5665" FT /gene_synonym="SC6A9.02" FT /product="conserved hypothetical protein SC6A9.02" FT /note="SC6A9.02, unknown, len: 213 aa; some similarity to FT several hypothetical proteins from Caenorhabditis elegans FT e.g. TR:G3168942 (EMBL:AF068713) T24A6.7 (206 aa), fasta FT scores; opt: 256 z-score: 328.5 E(): 4.7e-11, 31.2% FT identity in 154 aa overlap" FT /db_xref="InterPro:IPR012816" FT /db_xref="UniProtKB/TrEMBL:O86734" FT /protein_id="CAA19887.1" FT /translation="MARATLACMEKITGAERSPEARDSAGAVGGADGREALVARVRAGE FT RIKYLCFWGHRPLPDGRLGPSCLSQWWPSPFTVAGVEYATAEHWMMAGKARLFGDPEAE FT RRVLAAAHPAGAKKAGRLVRGFDEAVWERERFRIVVEGSVHKFASDPALRVFLLATGER FT VLVEASPVDRVWGIGLAADDEAAVDPERWRGPNLLGFALMAARERLRAGE" FT RBS complement(183669..183672) FT /note="possible RBS upstream of SC6A9.02" FT RBS 183830..183834 FT /note="possible RBS upstream of SC6A9.01c" FT CDS 183842..185377 FT /transl_table=11 FT /gene="SCO5666" FT /gene_synonym="SC8B7.12c" FT /gene_synonym="SC6A9.01c" FT /product="putative aldehyde dehydrogenase" FT /note="SC8B7.12c, probable aldehyde dehydrogenase, partial FT CDS, len: >315 aa; similar to many e.g. DHAB_ECOLI betaine FT aldehyde dehydrogenase (489 aa), fasta scores; opt: 861 z-s FT core: 1174.4 E(): 0, 44.2% identity in 301 aa overlap. Also FT similar to upstream ORF SC6A9.10c (E(): 0, 45.6% identity FT in 281 aa overlap). Contains PS00687 Aldehyde FT dehydrogenases glutamic acid active site, PS00070 Aldehyde FT dehydrogenases cysteine active site and Pfam match to entry FT PF00171 alde dh, Aldehyde dehydrogenases, score 153.00, FT E-value 5.3e-42. Overlaps and extends SC6A9.01c" FT /note="SC6A9.01c, probable aldehyde dehydrogenase, partial FT CDS len: 280 aa; highly similar to many e.g. FEAB_ECOLI FT phenylacetaldehyde dehydrogenase (499 aa), fasta scores; FT opt: 718 z-score: 924.3 E(): 0, 43.6% identity in 264 aa FT overlap. Contains PS00687 Aldehyde dehydrogenases glutamic FT acid active site" FT /db_xref="GOA:Q8CJQ9" FT /db_xref="HSSP:1A4S" FT /db_xref="InterPro:IPR016162" FT /db_xref="UniProtKB/TrEMBL:Q8CJQ9" FT /protein_id="CAD55360.1" FT /translation="MHNPGNATPDRFPAQDRFADGAQYIAGRLTKGTSGRTHTVVDPAT FT GEDVLTYDLAGPDDVDAAVAAARAAFPGWAGATPGERSDALHRFAAVLAERAEDFARAE FT SLQCGKPLKLTREFDVPGTVDNAAFFAGAARHLQGQSAGEYSGDHTSYVRREPIGVVGS FT IAPWNYPLQMAAWKILPAIAAGNTIVLKPAEITPLTSLMFAQAATEAGIPDGVINVVSG FT TGREAGEHLVAHPDVAMTSFTGSTAVGKRVAEVATATVKRLHLELGGKAPFLVFDDADL FT DAAVHGAVAGSLINTGQDCTAATRAYVQRPLYEAFVEKTAALMDTVRVGDPFAPGTDLG FT PLVSHVQRDRVAAFVDRARSYARVVTGGEVPQGDLKDGAYYRPTLVADAAQDSEVVQSE FT IFGPVLVVLPFDTDDEGIRLANDTPYGLAASAWSRDVYRANRATREIKAGCVWINDHIP FT IISEMPHGGYKASGFGKDMSAYSFEEYTQVKHVMFDNTAVAAKDWHRTVFGDR" FT misc_feature 184430..185326 FT /note="Pfam match to entry PF00171 aldedh, Aldehyde dehydro FT genases, score 153.00, E-value 5.3e-42" FT misc_feature 184634..184657 FT /note="PS00687 Aldehyde dehydrogenases glutamic acid active FT site" FT misc_feature 184718..184753 FT /note="PS00070 Aldehyde dehydrogenases cysteine active FT site" FT CDS 185490..186689 FT /transl_table=11 FT /gene="SCO5667" FT /gene_synonym="SC8B7.11c" FT /product="putative ABC-transporter polyamine-binding FT lipoprotein" FT /note="SC8B7.11c, probable ABC-transporter FT polyamine-binding lipoprotein, len: 399 aa; similar to e.g. FT POTF_ECOLI putrescine-binding periplasmic protein precursor FT (370 aa), fasta scores; opt: 327 z-score: 259.5 E(): FT 3.4e-07, 28.5% identity in 365 aa overlap. Also similar to FT upstream gene SC6A9.09c (E(): 0, 46.8% identity in 391 aa FT overlap). Contains PS00013 Prokaryotic membrane lipoprotein FT lipid attachment site and PS00017 ATP/GTP-binding site FT motif A (P-loop). Contains possible N-terminal region FT signal sequence peptide" FT /db_xref="GOA:O86832" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:O86832" FT /protein_id="CAA20222.1" FT /translation="MRRSLRSGRAALTRRSLLRASTGGALAVGGLGLLSGCGIPAAGKT FT EGGVSAEDHSKEEKQVRFSNWTEYMDVDESGRRHPTLEAFTKRTGVKVTYTEDINDNSE FT FFGKIQPQLAAGQETGRDIIVLTDWLAARLIRLGWVQKLDPANLPHAFTNLSPQFRNPD FT WDPGRAYSYPWQGISTVIAYNKKALDGIEVGTVSDLLDNPKLKGRVGFLTEMRDTMGMT FT LLDMGKDPARFTDDDYDAGIARLQKGVDRGQIRRFTGNDYTSDLSKGDFAACLAWAGDV FT VQLKADNPDIDFVIPDSGYVTSSDNMLIPNKARHKTNAERLIDYYYEPGPAAELAAYIN FT FVCPVDGVKDDLAKIDEDAANNPLIIPDQAMQAKSHSFRSLSSKEETAYEEKFAKLTGA FT " FT misc_feature 185568..185600 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid attac FT hment site" FT misc_feature 185601..185624 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 186695..187888 FT /transl_table=11 FT /gene="SCO5668" FT /gene_synonym="SC8B7.10c" FT /product="putative polyamine ABC-transporter ATP-binding p FT rotein" FT /note="SC8B7.10c, probable polyamine ABC-transporter ATP-bi FT nding protein, len: 397 aa; similar to many e.g. POTA_ECOLI FT spermidine/putrescine transport ATP-binding (378 aa), fast FT a scores; opt: 933 z-score: 1101.5 E(): 0, 47.7% identity i FT n 325 aa overlap. Contains PS00017 ATP/GTP-binding site mot FT if A (P-loop), PS00211 ABC transporters family signature an FT d Pfam match to entry PF00005 ABC_tran, ABC transporters, s FT core 216.70, E-value 3.6e-61" FT /db_xref="GOA:O86831" FT /db_xref="HSSP:1G29" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:O86831" FT /protein_id="CAA20221.1" FT /translation="MTTNPTKNQTAAKDGGGDVRLAGISKTYGSFTAVHPLDLTVPQGS FT FFALLGASGCGKTTTLRMIAGLEEPSGGTVHLGDQDVTALPPYKRPVNTVFQSYALFPH FT LDIYENVAFGLRRRGIKSVKKQVGEMLDLVQLGEQARKKPHQLSGGQQQRVAVARALIN FT HPKVLLLDEPLGALDLKLRRQMQLELKRIQTEVGITFVHVTHDQEEAMTMADQVAVMNA FT GRVEQLGAPADLYENPRTTFVANFLGTSNLIEAEVDTRSGDDVVVKAAGDKLVLPGARC FT SAPAKTGGKVLVGVRPEKISLTHADDAGSIPEGRNRITGRIGSTSFIGVSTQYVVDCAA FT CPEFEVYAQNIDRDPRLTPGAEVVLHWNPAHTFGLDADQSVLAGTMGDAGVAEGEAA" FT misc_feature 186824..187363 FT /note="Pfam match to entry PF00005 ABC_tran, ABC transporte FT rs, score 216.70, E-value 3.6e-61" FT misc_feature 186845..186868 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 187133..187177 FT /note="PS00211 ABC transporters family signature" FT RBS 187877..187880 FT /note="possible RBS upstream of SC8B7.09c" FT CDS 187888..188817 FT /transl_table=11 FT /gene="SCO5669" FT /gene_synonym="SC8B7.09c" FT /product="putative polyamine ABC-transporter integral memb FT rane protein" FT /note="SC8B7.09c, probable polyamine ABC-transporter integr FT al membrane protein, len: 309 aa; similar to many e.g. POTB FT _ECOLI spermidine/putrescine transport system permease (275 FT aa), fasta scores; opt: 548 z-score: 685.1 E(): 6.6e-31, 3 FT 6.9% identity in 274 aa overlap. Contains Pfam match to ent FT ry PF00528 BPD_transp, Binding-protein-dependent transport FT systems inner membrane component, score 38.20, E-value 1.8e FT -07" FT /db_xref="GOA:O86830" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:O86830" FT /protein_id="CAA20220.1" FT /translation="MSTLTEAPPPLSPPAPEQKPPRRRGRWTPYWLLLPGILWLVVFFA FT APMVYQASTSVQTGSLEEGYKVTWHFATYWDALTEYWPQFLRSVAYAASATVLCLLLGY FT PLAYLIAFRAGRWRNLIMILVIAPFFTSFLIRTLAWKTILADGGPVVGALNTLHVLDVT FT GWLGWTSGDRVLATPLAVVCGLTYNFLPFMILPLYTSLERIDGRLHEAAGDLYAKPSTV FT FRKVTFPLSMPGVVSGTLLTFIPATGDYVNASLLGSADTGMIGNVIQSQFLRVLDYPTA FT AALSFILMAAILAMVTFYIRKSGTEDLV" FT misc_feature 188485..188706 FT /note="Pfam match to entry PF00528 BPD_transp, Binding-prot FT ein-dependent transport systems inner membrane component, s FT core 38.20, E-value 1.8e-07" FT RBS 188802..188806 FT /note="possible RBS upstream of SC8B7.08c" FT CDS 188818..189618 FT /transl_table=11 FT /gene="SCO5670" FT /gene_synonym="SC8B7.08c" FT /product="putative polyamine ABC-transporter integral memb FT rane protein" FT /note="SC8B7.08c, probable polyamine ABC-transporter integr FT al membrane protein, len: 266 aa; similar to many e.g. POTC FT _ECOLI spermidine/putrescine transport system permease (264 FT aa), fasta scores; opt: 579 z-score: 718.8 E(): 8.8e-33, 3 FT 5.5% identity in 251 aa overlap. Contains Pfam match to ent FT ry PF00528 BPD_transp, Binding-protein-dependent transport FT systems inner membrane component, score 23.00, E-value 0.00 FT 7" FT /db_xref="GOA:O86829" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:O86829" FT /protein_id="CAA20219.1" FT /translation="MAFVNWFKRHVVVIAGLLTLAYLLLPNVVVTVFSFNKPNGRFNYE FT WQQFSTDAWKDPCGVAGLCGSLSLSLQIALWATLGATALGTAIAFALVRYRFRARGAIN FT SLIFLPMAMPEVVMAASLLTLFLNMGAQLGFWTILIAHIMFCLSFVVTAVKARVMSMDP FT RLEQAAQDLYAGPFQTFVRVTLPIAAPGIAAGALLAFALSFDDFIITNFNAGSTVTFPM FT FVWGSAQRGTPVQINVVGTAMFVIAVLFVLVSMVLGNRRNRRKA" FT misc_feature 189286..189498 FT /note="Pfam match to entry PF00528 BPD_transp, Binding-prot FT ein-dependent transport systems inner membrane component, s FT core 23.00, E-value 0.007" FT RBS 189642..189645 FT /note="possible RBS upstream of SC8B7.07c" FT CDS 189654..191081 FT /transl_table=11 FT /gene="SCO5671" FT /gene_synonym="SC8B7.07c" FT /product="putative oxidoreductase" FT /note="SC8B7.07c, possible oxidoreductase, len: 475 aa; FT some similarity to e.g. ORDL_ECOLI probable oxidoreductase FT ord L (426 aa), fasta scores; opt: 413 z-score: 280.3 E(): FT 2.4 e-08, 32.1% identity in 436 aa overlap" FT /db_xref="GOA:O86828" FT /db_xref="InterPro:IPR006076" FT /db_xref="UniProtKB/TrEMBL:O86828" FT /protein_id="CAA20218.1" FT /translation="MATGAMSRSNDWTKSLSDAQPVPYWLDDPGRPRPEAALTGTETCD FT LLVVGGGYSGLWTALIAKERDPGRDVVLIEGREVGWAASGRNGGFCAASLTHGLSNGLT FT RWPDDIHRLEELGARNLDAIEAAVARHGLDCDFERTGEIDVATEPHQARELEEWYAEIR FT AQGLAEGVEYLDAEAVREQVDSPTFRAGLWDRRGVAMVNPAKLAWGLKRACLALGVRVH FT EHTPALTLKPYGAGMAVRTPYGAVRARTVALGTNVFPNLVRRVRPYTVPVYDYALMTEP FT LSDGQLASVGWQNRQGLGDSANQFHYFRLSRDNRILWGGYDAVYPYGGRVRAEYDHRPE FT TYAKLAGHFFTCFPQLEGVRFTHAWGGAIDTCSRFSAFFGTAHRGRVAYAAGYTGLGVG FT ATRFGAEVMLDLLSGERTERTELEMVRTKPLPFPPEPFAWTGIALTKWSLARADAHGGR FT RNLWLRTMDRLGLGFDS" FT RBS 191193..191197 FT /note="possible RBS upstream of SC8B7.06c" FT CDS 191204..191662 FT /transl_table=11 FT /gene="SCO5672" FT /gene_synonym="SC8B7.06c" FT /product="hypothetical protein" FT /note="SC8B7.06c, unknown, len: 152 aa" FT /db_xref="UniProtKB/TrEMBL:O86827" FT /protein_id="CAA20217.1" FT /translation="MPGAKTAVAWLASVAPDPESCRRDWERDPSGVALLPAGKAWDVLI FT LPSRLGYPTLDVLSRVLDQPGPVLADFGDARTGFFVPAGTAARWLGTGIRTAGLGTWIV FT VPHPGGLSSGGTRWLIPPDGTGTLTDPSLLELAMHEAAAALAVEENGG" FT misc_feature 191709..193783 FT /note="match to D84193 Streptomyces lividans gene for chiti FT nase, from 23 to 2097" FT RBS 191794..191798 FT /note="possible RBS upstream of SC8B7.05c" FT CDS 191804..193636 FT /transl_table=11 FT /gene="SCO5673" FT /gene_synonym="SC8B7.05c" FT /gene_synonym="chiB" FT /product="secreted chitinase" FT /note="SC8B7.05c, chiB, secreted chitinase, len: 610 aa; FT almost identical to S. lividans TR:D1026067 (EMBL:D84193) FT chitinase ChiB (EC 3.2.1.14) (610 aa), 99.3% identity in FT 610 aa overlap, and highly similar to many e.g. CHIX_STROI FT Streptomyces olivaceoviridis exochitinase 1 precursor (EC FT 3.2.1.14) ( 597 aa), fasta scores; opt: 3484 z-score: FT 2485.6 E(): 0, 86.1% identity in 596 aa overlap. Contains FT PS01095 Chitinases family 18 active site. Contains possible FT N-terminal region signal peptide sequence" FT /db_xref="GOA:O86826" FT /db_xref="HSSP:1K85" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:O86826" FT /protein_id="CAA20216.1" FT /translation="MERAVVQRARPLARRPLVTLLTAAALAASGLTALTSAARAADADL FT ARNGGFESALDGWTCTAGTTVTSPVHGGTSALKATPAGADNARCSQTVSVKPDSPYTLS FT GYVRGTYVYLGASGTGTTDVSTWAQSAPDWQQLTTTFRTGPSTTRVTIYTHGWYGTGAY FT HADDISLTGPGGETQQPPAVPGGLKTGSVTSSAVALSWSPVPGATGYAVYRDGAKVSTV FT TGTSTTVTGLTPSTAYSFQVTAVNDAGESARSATVTATTAQRPDDGGGSSDLPAHALVG FT YLHASFANGSGYTRMADVPDSWDVIDLAFGEPTSVTSGDIRFERCPVAECPNVESDAEF FT KAAIKAKQAAGKKVLISIGGQNGQVQLTSTAARDKFVSSVSAIIDEYGLDGLDIDFEGH FT SLSLNADDTDFKNPKTPVIVNLVSAVKTLKAKYGDGFVLTMAPETFFVQLGYQYYGTGK FT WGGQDPRAGAYLPVIHALRDDLTLLHVQDYNSGSIMGLDNQYHSMGGADFHIAMTDMLL FT TGFPVAGDANNVFPPLRPDQVAIGMPASTQAGNGHVSPAEVTKALNCLTKKTDCGSYAT FT HGTWPDLRGLMTWSINWDRYSNWEFQKNFDAYFG" FT misc_feature 192968..192994 FT /note="PS01095 Chitinases family 18 active site" FT CDS complement(193575..194318) FT /transl_table=11 FT /gene="SCO5674" FT /gene_synonym="SC8B7.04" FT /product="putative integral membrane protein" FT /note="SC8B7.04, probable integral membrane protein, len: FT 247 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="GOA:O86825" FT /db_xref="InterPro:IPR000326" FT /db_xref="UniProtKB/TrEMBL:O86825" FT /protein_id="CAA20215.1" FT /translation="MRLREAWPAKLGVMPVSAPPRALSALVGLPVLLFALITWQVVADG FT PLVGVDERLSGALVHPDRFSELLSDLGNVQVAVPVLVVALAYAAWHGRVAGVGLWWLPP FT LAGALAMVLVPALVAPLKEWTDRPGTPAVPPAVGYYPSGHTATAVVAYGAATVLLLGRL FT RAPAVRRTLVVLCALLVLGTSYGLVRRGYHWPLDVVASWCLGVVLLAGVRLVERRTPPG FT RTPRDVSRSTRRSSSGTPSSSNGPS" FT stem_loop complement(194132..194178) FT /note="hairpin loop with 18bp stem" FT RBS 194381..194384 FT /note="possible RBS upstream of SC8B7.03c" FT CDS 194387..195157 FT /transl_table=11 FT /gene="SCO5675" FT /gene_synonym="SC8B7.03c" FT /product="hypothetical protein SC8B7.03c" FT /note="SC8B7.03c, unknown, len: 256 aa" FT /db_xref="GOA:O86824" FT /db_xref="InterPro:IPR011990" FT /db_xref="UniProtKB/TrEMBL:O86824" FT /protein_id="CAA20214.1" FT /translation="MTGEGRYEEVEAEARTLAALPRRPWRRRPPHWEARVLATGAAVMH FT GRMAEALDELDTLIAELEPVGLNSQMLRLIARSNRVVALSGLRRYAEAETVANGVLREL FT NQIAHRAPVSGLETNTLRHLATVLCGLARHEEAEAVVRGNLSRANGPAAGVLHTTLAQS FT LNGQGRYEEALAEVRRSPPRPPRYAAGHPDLVAAEALYGLGRRAEAEDAVRRSLADCER FT WLHPAHPRTGEARALLARVTGPKPGEESRGEPGE" FT stem_loop complement(195159..195206) FT /note="hairpin loop with 18bp stem" FT CDS complement(195557..196891) FT /transl_table=11 FT /gene="SCO5676" FT /gene_synonym="gabT" FT /product="putative 4-aminobutyrate aminotransferase" FT /note="SC8B7.02, gabT, probable 4-aminobutyrate FT aminotransferase, len: 444 aa; highly similar to e.g. FT GABT_ECOLI 4-aminobutyrate aminotransferase (EC 2.6.1.19) FT (426 aa), fasta s cores; opt: 1194 z-score: 1404.8 E(): 0, FT 45.5% identity in 424 aa overlap. Contains PS00600 FT Aminotransferases class-II I pyridoxal-phosphate attachment FT site and Pfam match to ent ry PF00202 aminotran_3, FT Aminotransferases class-III pyridox al-phosphate, score FT 516.20, E-value 5e-179" FT /db_xref="GOA:O86823" FT /db_xref="HSSP:1QJ3" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:O86823" FT /protein_id="CAA20213.1" FT /translation="MTALPQERRVVTAIPGPKSQELQARRTAVVAQGVGSTLPVFVARA FT GGGVIEDVDGNRLIDFGSGIAVTSVGASAEAVVRKASAQLADFTHTCFMVTPYEGYVAV FT AEALAELTPGDHAKKSALFNSGAEAVENAVKIARAYTKRQAVVVFDHGYHGRTNLTMAL FT TAKNMPYKHGFGPFAPEVYRVPVAYGYRWPTGAENAGPEAAAQAIDQISKQVGAENVAA FT VIIEPVLGEGGFIEPAKGFLPAIREFASDNGIVFVADEIQSGFCRTGQWFACEDEGIVP FT DLITTAKGIAGGLPLSAVTGRAEIMDAAHSGGLGGTYGGNPVACAGALGAIETMKELDL FT NARAKDIEAVMKSRLAAMAEKFDVIGDVRGRGAMIAIELVKDRETKEPNPAATAALAKA FT CHQEGLLVLTCGTYGNVLRFLPPLVIGEDLLNEGLDIIEQAFTRV" FT misc_feature complement(195623..196753) FT /note="Pfam match to entry PF00202 aminotran_3, Aminotransf FT erases class-III pyridoxal-phosphate, score 516.20, E-value FT 5e-179" FT misc_feature complement(196013..196126) FT /note="PS00600 Aminotransferases class-III pyridoxal-phosph FT ate attachment site" FT RBS complement(196898..196902) FT /note="possible RBS upstream of gabT" FT RBS 197238..197241 FT /note="possible RBS upstream of SC8B7.01c" FT CDS 197250..199280 FT /transl_table=11 FT /gene="SCO5677" FT /gene_synonym="SC5H4.01" FT /gene_synonym="SC8B7.01c" FT /product="putative ATP/GTP binding protein" FT /note="SC5H4.01, possible ATP/GTP binding protein (putative FT membrane protein) (fragment), len: >350 aa" FT /note="SC8B7.01c, probable ATP/GTP binding protein FT (putative membrane protein), partial CDS, len: >604 aa. FT Contains PS00017 ATP/GTP-binding site m otif A (P-loop), FT and two possible transmembrane domains at C-terminus" FT /db_xref="InterPro:IPR000318" FT /db_xref="UniProtKB/TrEMBL:Q8CJI6" FT /protein_id="CAD55361.1" FT /translation="MPPRPARAPGASDGSAFLTWLRTPRPQALPGVWRFGHRPRPEEEA FT ERVPGRQLLSGAVIAFLVGWLIWSLLWNGYLGGWWLLPLYAMIPDSWAEPHSFASVVVV FT YAYYVLIAGIVMVGVGRLGRWGEIWRRYGPPAWRRAVPGAVPAPAPEEDPAAWPALRAA FT GAHDAAERLAADARSGLMRDVDHARIARAWQGVQRGRHSLATFTGAVLSHGSAACPHPS FT GARDLPVRQARHDLVTGQVRIGTAADDARNPYAYRGTGLALGPDLLGTSLLAVGPAGSG FT KTGSVVRPLSESLCLHALAGRAAVVVVGAAGADLGPADAYDVVVRIGNPDSVYDLDLYG FT GTTDPDEAAVILAEALAGDLTDQHQGGDTRRSTTVLAQLLGPFRAVHGRFPGVPELRQL FT LDGAPGPLAELRAGLRAAGQESLLRELDARERQQGRPGDVGGVLADRVALLDRPAFAPF FT FDTSGQSRPFSLKALDHPVRVRIDLPQRGHADASRMLARLVLAQFTASVSVREDRSLFA FT CLVLDDASGVVTPEAVRGVQRLRSAGAGVVLTLRTLDDVPRPLRGPLLGAIGCRMALSG FT LTPWDGQDFAEVWGKEWTEARDVTDRQIIAETPAGKAVHMLRRVITGKAPTARAVTVRQ FT VERERWSASELAHAVPAGHAVLSLTSVKGEHAPPLLVDLRG" FT misc_feature 198075..198098 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 199444..201102 FT /transl_table=11 FT /gene="SCO5678" FT /gene_synonym="SC5H4.02" FT /product="putative regulatory protein" FT /note="SC5H4.02, possible regulatory protein, len: 552 aa; FT similar to TR:Q9ZBP0 (EMBL:AL034492) Streptomyces FT coelicolor putative regulatory protein SC6C5.05c, 569 aa; FT fasta scores: opt: 310 z-score: 323.3 E(): 1.5e-10; 30.0% FT identity in 587 aa overlap" FT /db_xref="InterPro:IPR012914" FT /db_xref="UniProtKB/TrEMBL:Q9KYT7" FT /protein_id="CAB91114.1" FT /translation="MPPTLASLVHHSALKLTVRAGEDRLDVPVRWAHVSELADPVPYME FT GGELLLITALKLDAEDPEAMRRYVKRLAGAGVVGLGFAVGVNYDDVPEALVDAARQEGL FT PLLEVPRRTPFLAISKAVSAAIAADQYRAVTAGFAAQRELTRRTLTDGPEGLLAALAAQ FT VDGWAALYDASGAVVASAPEWAGRRAARLTADVQRLRERPAPASSVVGGAGNTGHSENA FT DRVELHSLGTSRRPRAALAVGTAAALGTAERYAVHSAIALLTLTTERSRSLHEAGLRID FT AAVLRMLLAGEPDHARTVAGDLYGGLLDAPFRVIVAESGAARNRGPTAAHTAAGTGGDP FT GGDPLGTLGSLAEAAESAAARAGEAVLAVPDGERLVVLATDGGAAVAACVEHASALEAA FT RPAAEPLAGGDEESLVVGVSAPSGPIAASAAYKQAQQALSVARRRGRVCVEHEHVAAGS FT VLPLLADDAVRAFADGLLRALRDHDATGRGDLVASVRAWLSRHGQWDAAAADLGVHRHT FT LRYRMRRVEEILGRSLDDPDVRMELWLALKATAPE" FT CDS 201246..202691 FT /transl_table=11 FT /gene="SCO5679" FT /gene_synonym="SC5H4.03" FT /product="putative aldehyde dehydrogenase" FT /note="SC5H4.03, probable aldehyde dehydrogenase, len: 481 FT aa; similar to TR:O66573 (EMBL:AE000677) Aquifex aeolicus FT aldehyde dehydrogenase AldH1, 476 aa; fasta scores: opt: FT 1129 z-score: 1260.2 E(): 0; 39.9% identity in 471 aa FT overlap and to SW:GAPN_STRMU (EMBL:L38521) Streptococcus FT mutans NADP-dependent glyceraldehyde-3-phosphate FT dehydrogenase (EC 1.2.1.9) GapN, 475 aa; fasta scores: opt: FT 893 z-score: 997.5 E(): 0; 35.4% identity in 477 aa FT overlap. Contains Pfam match to entry PF00171 aldedh, FT Aldehyde dehydrogenase family" FT /db_xref="GOA:Q9KYT6" FT /db_xref="HSSP:1EUH" FT /db_xref="InterPro:IPR016162" FT /db_xref="UniProtKB/TrEMBL:Q9KYT6" FT /protein_id="CAB91115.1" FT /translation="MTSTHAFWLAGRQAAGESGFDVTSPWDGTTVGTVSLPTDAQVEEA FT VAAAYAVRDEFAATPAHVRAAALDHVGRRLAERTEEIARLISAENGKPVKWARGEVGRA FT VSVFRFAAEEARRFNGGEAQRLDTDAGGQGRLALTRRFPKGVVLGIAPFNFPLNLCAHK FT IAPAIAAGAPLILKPAPATPLSGLILGELLAETDLPAGSWSILPVPNDKMPALVQDERL FT PVISFTGSETVGYAIMDSVPRKHCTLELGGNGAAVVLADWASDEDLDRAATRIATFSNY FT QGGQSCISVQRVIADAAVYDRLLPRIVAAVEAQVTGDPNDDATDVGPLVSEAAAERVEA FT WVREAVDAGAKLLTGGKRDGASYAPTVLTELPADTTLAHEEVFGPVLSVQRVTGEAEAF FT AAVNDSKYGLQAGVFTHDLQAAFRAHRALEVGGVVIGDIPSYRADQMPYGGAKQSGVGR FT EGVKFAMDDYTYERVLVLTGLAL" FT misc_feature 201273..202679 FT /note="Pfam match to entry PF00171 aldedh, Aldehyde FT dehydrogenase family, score 357.30, E-value 1.6e-103" FT CDS complement(202701..203114) FT /transl_table=11 FT /gene="SCO5680" FT /gene_synonym="SC5H4.04c" FT /product="putative cytidine deaminase" FT /note="SC5H4.04c, probable cytidine deaminase, len: 137 aa; FT similar to TR:O53367 (EMBL:AL021841) Mycobacterium FT tuberculosis cytidine deaminase Cdd, 133 aa; fasta scores: FT opt 185 z-score: 244.6 E(): 3.6e-06; 37.4% identity in 115 FT aa overlap and to SW:CDD_MOUSE (EMBL:AA388666) Mus musculus FT cytidine deaminase (EC 3.5.4.5) Cdd, 146 aa; fasta scores: FT opt: 173 z-score: 229.1 E(): 2.6e-05; 29.2% identity in 113 FT aa overlap. Contains Pfam match to entry PF00383 FT dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase FT zinc-binding region and match to Prosite entry PS00903 FT Cytidine and deoxycytidylate deaminases zinc-binding region FT signature" FT /db_xref="GOA:Q9KYT5" FT /db_xref="InterPro:IPR002125" FT /db_xref="UniProtKB/TrEMBL:Q9KYT5" FT /protein_id="CAB91116.1" FT /translation="MTSQTNPVDHELIEAAAHVARTRCRGDNHTMAAAARARDGRIVTA FT VNAYHFTGGPCAELVVVGAAAAQGVYELETIVAVGDRERGVVPPCGRCRQVLLDYFPGL FT EVIVGEGDRVRAVPVTDLLPETYVWADHQLDAG" FT misc_feature complement(202800..203045) FT /note="Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine FT and deoxycytidylate deaminase zinc-binding region, score FT 10.30, E-value 0.027" FT misc_feature complement(202824..202949) FT /note="PS00903 Cytidine and deoxycytidylate deaminases FT zinc-binding region signature" FT CDS complement(203140..204315) FT /transl_table=11 FT /gene="SCO5681" FT /gene_synonym="SC5H4.05c" FT /product="putative glycosyl transferase" FT /note="SC5H4.05c, possible glycosyl transferase, len: 391 FT aa; similar to TR:Q9X7Z1 (EMBL:AL049497) Streptomyces FT coelicolor putative glycosyl transferase SC6G10.05c, 412 FT aa; fasta scores: opt: 1364 z-score: 1557.1 E(): 0; 56.4% FT identity in 385 aa overlap. Contains Pfam match to entry FT PF00534 Glycos_transf_1, Glycosyl transferases group 1" FT /db_xref="GOA:Q9KYT4" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q9KYT4" FT /protein_id="CAB91117.1" FT /translation="MSDSRARTLIVTNDFPPRQGGIETFVRELADRFPPDEVVVLTSAP FT TAAPGSGESFPYPVVRHPVRTLLPTPGATAHAAAVARRYGCDRVWFGAAAPLALMAGRL FT RRTAGIGTAVASTHGHEVWWARTPGPRALLRRIGSQVDTLTWLGERTRAPIEAALAAGT FT RTARLVPGVDTGTFHPAADGTRVRTRYGLGHRPVILCAARLVPRKGQDTLIRALPWVRR FT AVPDAVLLLVGDGPHAAGLRQLALREGVMDSVHFAGGHPHHALPAFYAAADAFAMPCRT FT RKGGLELEGLGIVYLEAAASGLPVVAGDSGGAPDAVREGETGHVVDGRSVAATADRLIR FT LLRDPRLARAMGGAGRDWVRTAWSWDHSYATLRDLLSGRTAGCRTVGPADT" FT misc_feature complement(203242..203727) FT /note="Pfam match to entry PF00534 Glycos_transf_1, FT Glycosyl transferases group 1, score 78.90, E-value FT 1.9e-21" FT CDS complement(204312..205445) FT /transl_table=11 FT /gene="SCO5682" FT /gene_synonym="SC5H4.06c" FT /product="putative integral membrane protein" FT /note="SC5H4.06c, possible integral membrane protein, len: FT 377 aa; similar to TR:Q53873 (EMBL:AL031317) Streptomyces FT coelicolor putative integral membrane protein SC6G4.11, 411 FT aa; fasta scores: opt: 180 z-score: 193.2 E(): 0.0027; FT 33.8% identity in 340 aa overlap. Contains possible FT hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9KYT3" FT /protein_id="CAB91118.1" FT /translation="MRKTFGDRVATDAGWPVERYAWAGCAVAVAGFAQVSDLVTHRVWG FT WAAAAGYTLAAFLASGAVPRPAARAAAVAGAVVAPLVGLVVTGLGQSEVAVIERSGRLL FT AATGSPYVTAPSAVGDFNPYLPGMALFGLLPGDPRWWLGGVFVASLGAAGLRSPALLLA FT CPLVALPLAVGGVDLPVAGLMCLGLALAGRGRPGGAGLALGAAAALKWTAWPALPVALA FT LVAVRQGGRPALRCAGVGLGTGTAVVLPFALTDPAGFFRNVVAFPFGLTATDSPAGSPL FT PGRLLAAHVPGGTVIALALLTVGALLTGASLAVRPPETLRAAAGRLALGLGLATALMPA FT TRFGYLVYPLLLAALAHGAARRDPEVTGRPVERTLAR" FT RBS complement(204326..204332) FT RBS 205582..205586 FT CDS 205588..206784 FT /transl_table=11 FT /gene="SCO5683" FT /gene_synonym="SC5H4.07" FT /product="putative two-component system sensor kinase" FT /note="SC5H4.07, probable two-component system sensor FT kinase, len: 398 aa; similar to TR:Q9X851 (EMBL:AL049630) FT Streptomyces coelicolor putative two-component sensor FT kinase SCE126.08c, 401 aa; fasta scores: opt: 581 z-score: FT 640.5 E(): 3.2e-28; 36.8% identity in 361 aa overlap and to FT TR:BAA88406 (EMBL:AB016841) Streptomyces thermoviolaceus FT ChiS protein, 448 aa; fasta scores: opt: 445 z-score: 491.3 FT E(): 6.6e-20; 34.5% identity in 391 aa overlap. Contains FT possible hydrophobic membrane spanning regions in FT N-terminal domain" FT /db_xref="GOA:Q9KYT2" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9KYT2" FT /protein_id="CAB91119.1" FT /translation="MSTSPPQRLRDWIAAPAYPWITGGAVTAGAVVELIVIPGGVTTTV FT GVLVSAVSLMWRRSFPPVAVLTVAAGLIGFAGDVNLYLAIMVSGLTGCYSLGRNRVLHP FT ALTVTGGALGALCVNLVHINTWSRMDLPVPALWERGSLSLFAESFLVTVVVFGAVMMGD FT AVRSREETRTERSLAQAQLIAMERQQAAEAERAAIARELHDIVSHSVSMIAVQAESATY FT TTPGLTPEARDGFQQIAATARSSMAELRRLLGVLRTPQGESALTSPQPTLDHLAELVDQ FT HRAVGGTAELRITGERVALPAAWELSAYRIAQEALTNARKHAPGARTVVEVDYGADRLL FT TLRVQDDGPGTDSRPGAGAGHGLTGMRERAALVGGRLSAGAGPDGGFLVEAELPWGSG" FT RBS 206774..206777 FT CDS 206781..207494 FT /transl_table=11 FT /gene="SCO5684" FT /gene_synonym="SC5H4.08" FT /product="putative two-component system response regulator" FT /note="SC5H4.08, probable two-component system response FT regulator, len: 237 aa; similar to TR:Q9X8Q7 FT (EMBL:AL049754) Streptomyces coelicolor putative FT two-component system regulator SCH10.18c, 228 aa; fasta FT scores: opt: 780 z-score: 922.5 E(): 0; 58.7% identity in FT 225 aa overlap and to TR:BAA88407 (EMBL:AB016841) FT Streptomyces thermoviolaceus ChiR protein, 213 aa; fasta FT scores: opt: 567 z-score: 674.0 E(): 4.4e-30; 46.9% FT identity in 213 aa overlap. Contains Pfam matches to FT entries PF00072 response_reg, Response regulator receiver FT domain and PF00196 GerE, Bacterial regulatory proteins, FT luxR family and match to Prosite entry PS00622 Bacterial FT regulatory proteins, luxR family signature and also a FT possible helix-turn-helix motif at residues 180..201 (+2.70 FT SD)" FT /db_xref="GOA:Q9KYT1" FT /db_xref="HSSP:1A04" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9KYT1" FT /protein_id="CAB91120.1" FT /translation="MRPAEPAKEPRVIRTLVADDQAVVRTGFVNLLNTQEDIEVVAEAE FT DGAQAVLSAGETRPDLALLDIRMPHKNGIEAAREILAASGGATKILMLTTFGLDEYVYD FT ALAAGAGGFLLKDATFPELLHAVRVVAGGNALLSPEITKRLIAEFVHARGSRLPVPAAG FT DLTARETEVLTLIARGLSNAEIAGRLTITDHTVKTHINRLFAKLELRDRAQAVIVAYEL FT GLVRAGGESGGARHR" FT misc_feature 206817..207161 FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 106.30, E-value 6.1e-28" FT misc_feature 207264..207461 FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 73.70, E-value FT 3.8e-18" FT misc_feature 207315..207398 FT /note="PS00622 Bacterial regulatory proteins, luxR family FT signature" FT CDS complement(207536..210418) FT /transl_table=11 FT /gene="SCO5685" FT /gene_synonym="SC5H4.09c" FT /product="putative sugar hydrolase" FT /note="SC5H4.09c, probable sugar hydrolase, len: 960 aa; FT similar to TR:Q59506 (EMBL:L06134) Microbispora bispora FT glucan-glucohydrolase (EC 3.2.1.74) (glucan FT 1,4-beta-glucosidase) (exo-1,4-beta-glucosidase) BglA, 986 FT aa; fasta scores: opt: 1257 z-score: 1346.1 E(): 0; 47.7% FT identity in 979 aa overlap. Contains Pfam matches to FT entries PF00933 Glyco_hydro_3, Glycosyl hydrolase family 3 FT N terminal domain and PF01915 Glyco_hydro_3_C, Glycosyl FT hydrolase family 3 C terminal domain" FT /db_xref="GOA:Q9KYT0" FT /db_xref="InterPro:IPR001764" FT /db_xref="UniProtKB/TrEMBL:Q9KYT0" FT /protein_id="CAB91121.1" FT /translation="MSAATPPFRDPQLPFAKRVDDLMSRLTLDEKTAFLHQFAPAVERL FT GIAPFRTGQEALHGVAWMGPATVFPQAVGLGATWNEELVRRVGEAVSKEARAMRARDDR FT VGLNVWSPTVNLLRHPLWGRNEEGYSEDPRLTSAVATAYTRGLRGDHPAYWRTAPVLKH FT WLAHNNETDRDTSSSSVRPRVLHEYDLRAFRDTVEAGAVAGVMPAYNLVNGRPNHLSPH FT LGRHLRTWTQEDLLVCSDAGAPSNLVDSEHYFDTHEEATAAALRAGVDSFTDHGTDSSK FT IVARVRGALEAGLLTEADVDAAVRRQLSVRFRLGEFDPENDPYSGAADTGADFDTPEHR FT ALARDAAEQAVVLLKNDGVLPLAPETRVAVVGLLADECKLDWYSGTLIHRSTPLEGLYE FT RFGADRVSFAEGVDRVRLRTADGRFLHVLPADDASAEAPGTEGALDPALLAGRTDLPPL FT TTDAVGTELALIDWGEGVLTLRASDGRYLSVAEDGFVRASADQPGGWVVQETFRLEPHD FT DGHLLRHTGTGRPVQVAADGVKVAAPDAAAGAAAGGAGSADAEVFELVVVERGEDAVTR FT VAAGADVVVVVAGNDPHINGRETEDRTTLRLPAQQERLLRAARAANPATVLALVSAYPY FT AVGVETLPAVLWTAHGGQAAGTALARILAGDVSPAGRLPQTWYSDDADLPGLLDYDVIG FT GRQTYLYFEGTPLFPFGHGLSYASFGYGDLTAQVRDGAVAVSFTVTNTGEVSADEVAQL FT YVRAEAPSVPRPRRELLAHRRLTLAPGASDRVSFEVPLSALAFWDVAHDRWRLEPGPYA FT LLVGASSEDVRLTTTVTIDGEPAVPRPVGARGVQAVDFDEQSGTEIVDRTKAAGDAVAA FT VSGRTGELLYRDCDFGAGAAGVTVSVAGAGSVEVALDGGPAVAVLSPDAPTAGPYDYVE FT LASAFTAEGVHDLRVTLRGALRLAHVGFSG" FT misc_feature complement(208466..209422) FT /note="Pfam match to entry PF01915 Glyco_hydro_3_C, FT Glycosyl hydrolase family 3 C terminal domain, score 51.10, FT E-value 2.5e-11" FT misc_feature complement(209540..210376) FT /note="Pfam match to entry PF00933 Glyco_hydro_3, Glycosyl FT hydrolase family 3 N terminal domain, score 232.20, E-value FT 7.5e-66" FT CDS 210668..212353 FT /transl_table=11 FT /gene="SCO5686" FT /gene_synonym="SC5H4.10" FT /product="putative lipoprotein" FT /note="SC5H4.10, probable lipoprotein, len: 561 aa; similar FT to SW:LPLA_BACSU (EMBL:L03376) Bacillus subtilis LplA, 502 FT aa; fasta scores: opt: 364 z-score: 402.3 E(): 6e-15; 23.6% FT identity in 483 aa overlap. Contains correctly situated FT match to Prosite entry PS00013 Prokaryotic membrane FT lipoprotein lipid attachment site, possible N-terminal FT region signal peptide sequence and possible colied-coil FT region at residues 562..575" FT /db_xref="GOA:Q9KYS9" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q9KYS9" FT /protein_id="CAB91122.1" FT /translation="MTPNAASGPSRRSFLASTAVATAAVAGGVPLLSACGGSDGGSRDG FT TTSGKDAAKLLPSYVAASVVTPDIPSKNGSAVGFTGKLDLADLKTSVPEKLGKGGRVTV FT MSPFWGSPPKEDNAYYKAMNDLIGVDVVWQNQDGNTYDQKLGAVLASSEVPDVVVVPGW FT NMTGKIPSAIIGKFADLGPYLSGDAVKEYPNLAAIPTDAWQRSIFGGKLLGLPMPSSYV FT SGIVPLYRQDVFEKEGYEVPRSCDEFMAMAKDATNARAKRWACLDMKWTAFNAFGVLSG FT NEKSLGWNQVDGKLVYRAETDEYLEALEWTRKLFAAGVVHPDAKLGKSNAADPGPKFAA FT GEFLVYNQDISQWWSRTAEQATQNPGFRIWGMDFFGHDGGAPTLWAQNPASIFAFVNKK FT ASKSVIRDVLAVANVTAAPYGTKEYMATNYGVEGTHYTVKDGVPTKTDQGNIDVMNAYV FT MVASPAATIAHPDFPEVAKGQVEWQQRTGAVTRKPTFYGMQIVEPARYTNLSNDFEQLE FT DDIVRGRKKIGDMQQAVSDWRNKGGDKLRDWYRKLLDENGPAAG" FT misc_feature 210740..210772 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS 212370..212374 FT CDS 212381..213421 FT /transl_table=11 FT /gene="SCO5687" FT /gene_synonym="SC5H4.11" FT /product="putative transport system integral membrane FT protein" FT /note="SC5H4.11, probable transport system integral FT membrane protein, len: 346 aa; similar to SW:LPLB_BACSU FT (EMBL:L19163) Bacillus subtilis LplB protein, 318 aa; fasta FT scores: opt: 814 z-score: 950.7 E(): 0; 38.2% identity in FT 309 aa overlap. Contains Pfam match to entry PF00528 FT BPD_transp, Binding-protein-dependent transport systems FT inner membrane component and match to Prosite entry PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign. Contains also possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q9KYS8" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9KYS8" FT /protein_id="CAB91123.1" FT /translation="MSHSTVPRTRAEADATKKTPAASGDATGPDGGRRQPGKPPSLRLR FT FRRDRVLLLMTLPAVLLVLLFNYVPILGNVVAFQEYDPYLSDNGIVSILHSPWVGLENF FT QRIFEDSAFWNSVRNTLVLFLLQLVLYFPIPIALALLINSVVRPRVRAISQAILYLPHF FT FSWVLVIAVFQQLLGGAGLLSQLLRDHGYDGLGVMTDPDTFKFLVTAQSVWKDAGWGII FT VFLAALASVSPDLYEAAAMDGANRWRRMWHVTLPALRPVIALLLVLRVGDALTVGFEQI FT LLQRDAVGPGAAEVLDTFVWWNGVRNQDFGYAAAAGLVKGVISLGLVLVANKVAHLMGE FT QGVYKK" FT misc_feature 213059..213283 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 45.20, E-value 1.4e-09" FT misc_feature 213062..213148 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS 213418..214389 FT /transl_table=11 FT /gene="SCO5688" FT /gene_synonym="SC5H4.12" FT /product="putative transport system integral membrane FT protein" FT /note="SC5H4.12, probable transport system integral FT membrane protein, len: 323 aa; similar to SW:LPLC_BACSU FT (EMBL:L19164) Bacillus subtilis LplC, 295 aa; fasta scores: FT opt: 669 z-score: 758.9 E(): 0; 38.0% identity in 276 aa FT overlap. Contains Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component. Contains also possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q9KYS7" FT /db_xref="InterPro:IPR016160" FT /db_xref="UniProtKB/TrEMBL:Q9KYS7" FT /protein_id="CAB91124.1" FT /translation="MTAVPEATAVRDTTAASGTLPRRPRPWEAPPRPVWEEKPSRAGLA FT GKGLVLLLACLGILFPLWIVVVTSLSSRRSIDEAGGLVMIPKDITFVAYQELLSGGQVT FT RAALVSIGVTLVGTLFSMAVSVLCAYGLSRSGSLGHRWILMVLLATMFFSAGLIPTYLL FT VQSLGLTDSYLALILPSAISVFNILVLRGFFMGISQELIDSARIDGAGDLRILWRIVLP FT LSRAVVAVITLFYAVGYWSAWFNASLYLNDQDMLPLQNVMIQLVQKQEAPVGLGQAIKT FT GELSGLAVQMAVMVMALLPVAVLSPFVQRHFRKGMLTGAVKG" FT misc_feature 213994..214227 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 29.80, E-value 6.4e-05" FT CDS 214389..216359 FT /transl_table=11 FT /gene="SCO5689" FT /gene_synonym="SC5H4.13" FT /product="putative beta-galactosidase" FT /note="SC5H4.13, probable beta-galactosidase, len: 656 aa; FT similar to SW:BGAL_BACST (EMBL:M13466) Bacillus FT stearothermophilus beta-galactosidase I (EC 3.2.1.23) FT (lactase) BgaB, 672 aa; fasta scores: opt: 1761 z-score: FT 2065.7 E(): 0; 41.3% identity in 634 aa overlap and to FT TR:CAB76326 (EMBL:AL158061) Streptomyces coelicolor FT probable beta-galactosidase SC6D11.03c, 681 aa; fasta FT scores: opt: 1739 z-score: 1719.0 E(): 0; 46.0% identity in FT 670 aa overlap" FT /db_xref="GOA:Q9KYS6" FT /db_xref="HSSP:1KWG" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:Q9KYS6" FT /protein_id="CAB91125.1" FT /translation="MPGLSDATRRRILFGGDYNPEQWPEETWPEDVRLMKTAGVNSVTL FT GVFSWSKLEPRPGVHDFGWLDRLMDLLHEGGIGVVLATPTASPPPWLGHLHPDTLPRDA FT DGRTEWWGGRQHFSHSSTAYRRHAAAITEALAARYGGHPALTMWHINNEYCTYDHGDEA FT ATRFRRWLRDRYGTLDALNTAWGTAFWSQGYGDWAEVVPPRRAHYLRNPTQVLDFRRFT FT SDMLLECCTAERDIVRRHTPHIPVTTNFMPLWSGQDAWRWAEEEDVVSVDLYPDPRDPF FT GAQEGALVQDMTRSQARGPWMLMEQAAGAVNWRGVNHPKPRGLNRLWSLQAVARGADAV FT CYFQWRQSRQGAEKFHSGMVSHAGERGRTYQEVKQLGADLARIAPHVTGGAVAADVAVL FT HDWHSWWAGDQEARPSREVDYPDVLRAWHRALWQAGLTTDFARPDHDLTGYRLVVVPQL FT YLLTDAAVDNLVAHVRGGATLVCGFLTGVADQDDRIRPGAMDVRLRELFGIRTLHEWWP FT LRPGERAECEGGLRGTLWSEELEPDGTADETIAYRGGELDGLPAVLRKGRAWYLSTLPE FT PDRLRALLARAAADAGVRPVLDGLPDGVEAVRRGDLLFLLNHGREPVTVDLPGTHHDLL FT TQTTATDRITLGRYGAAVLKP" FT CDS 216356..218599 FT /transl_table=11 FT /gene="SCO5690" FT /gene_synonym="SC5H4.14" FT /product="conserved hypothetical protein SC5H4.14" FT /note="SC5H4.14, hypothetical protein, len: 747 aa; similar FT to TR:CAB36703 (EMBL:AL035521) Arabidopsis thaliana FT hypothetical 94.0 kD protein AT4G34260, 847 aa; fasta FT scores: opt: 322 z-score: 354.9 E(): 2.6e-12; 25.6% FT identity in 754 aa overlap" FT /db_xref="InterPro:IPR016518" FT /db_xref="UniProtKB/TrEMBL:Q9KYS5" FT /protein_id="CAB91126.1" FT /translation="MSATPVHGTWEPEPAARWEDAFLSGNGHHGVLVSGDPDADRVIVT FT HHTLVRPDGDDGHRRPPAVAAGLTALQDRLLAGDATAAEDFTDGRPLQWVRPFHPAFQL FT RLNRPPGDDTHHPHDTRRTHAPYRRAVDFTTGETTAARGDWTSRVFVSRADDVIVQRVT FT APRLTLDLSLDPRLPGAPAGLRIGHGAVLAPEGALLTLRARYPGSDLAYTGVTLVAVTG FT GTVRLVPPGVLVEGATEVLLLTRVRRHTGELDTVAESRALRDLLDGTSHAAPYDGLLAR FT HLTRHRTAYDRVTLDLAADPAERALPGSELLARPGGPALLERLFAAGRYHLLSASGLLP FT PRLTGLWTGDWNTAWSGAFTTNANLNLQTASAAAAALPEVTEAHAALVHRQLPDWRDNA FT REIFGTRGVVAPSHTDGECGHTHHFSREYPLHLWTAGADWLLKPLVEHDETRDAHDPRT FT TAALAEAALFYEDFLHRTDKHGHLAVVPSYSPENRPANASWGTLNAAMDLSAARHALLT FT AADRHPEHADRWRALADRLPAHRVNADGALAEWAWPGLTDTYDHRHLSHLYGVWPLEEI FT NPYDTPDLAEAAHRALELRGAENDSAHGHLHHALVAARLRDGDRVAHALGRVLDGDYFH FT ASLMSAHYPHRDVYNADAAHALPAVLIEMLVQSTPGRLVLLPALPASCPQGELRGVRTR FT FGAVLDLTWRPDGSATAVLRPDRTRRIELRTPSGAEPLDLVAGEDRAISVPAR" FT CDS 218638..219372 FT /transl_table=11 FT /gene="SCO5691" FT /gene_synonym="SC5H4.15" FT /product="putative secreted sugar hydrolase" FT /note="SC5H4.15, probable secreted sugar hydrolase, len: FT 244 aa; similar to SW:GUNS_ERWCA (EMBL:M32399) Erwinia FT carotovora endoglucanase S precursor (EC 3.2.1.4) FT (endo-1,4-beta-glucanase S) (cellulase S) CelS, 264 aa; FT fasta scores: opt: 283 z-score: 330.2 E(): 6.2e-11; 33.2% FT identity in 253 aa overlap. Contains Pfam match to entry FT PF01670 Glyco_hydro_12, Glycosyl hydrolase family 12 and FT possible N-terminal region signal peptide sequence" FT /db_xref="GOA:Q9KYS4" FT /db_xref="HSSP:1OA3" FT /db_xref="InterPro:IPR002594" FT /db_xref="UniProtKB/TrEMBL:Q9KYS4" FT /protein_id="CAB91127.1" FT /translation="MAPRTRPTRTRARTRTLTALLAPALALGATVGLAAAPAQAAVWNS FT CDQWGNTSLNGYTLYNNIWGSGAGSQCVWANSGTDWGVWADHPNTDGIKSYPNAKKVIN FT KPITSLSSLTSSYNVTVPSSGAYNTSYDIWDTDYDYEIMLWVNHHGAVGPLGTFQGSVG FT LGGHTWDVYKGNNGANEVFSFLRTSDSNSGTVNILPILKWIKDTKGWMGNETIGDVQFG FT YEITSSAGGLDFRTNNLTVSGG" FT misc_feature 218926..219363 FT /note="Pfam match to entry PF01670 Glyco_hydro_12, Glycosyl FT hydrolase family 12, score 44.40, E-value 2.6e-09" FT CDS complement(219514..220527) FT /transl_table=11 FT /gene="SCO5692" FT /gene_synonym="SC5H4.16c" FT /product="putative transcriptional regulator" FT /note="SC5H4.16c, probable transcriptional regulator, len: FT 337 aa; similar to SW:CELR_THEFU (EMBL:AF086819) FT Thermomonospora fusca transcription regulator CelR, 340 aa; FT fasta scores: opt: 440 z-score: 531.7 E(): 3.7e-22; 31.6% FT identity in 339 aa overlap. Contains Pfam matches to FT entries PF00356 lacI, Bacterial regulatory proteins, lacI FT family and PF00532 Peripla_BP_like, Periplasmic binding FT proteins and sugar binding domain of the LacI family and FT match to Prosite entry PS00356 Bacterial regulatory FT proteins, lacI family signature. Contains also possible FT helix-turn-helix motif at residues 2..23 (+6.39 SD)" FT /db_xref="GOA:Q9KYS3" FT /db_xref="HSSP:1LCC" FT /db_xref="InterPro:IPR001761" FT /db_xref="UniProtKB/TrEMBL:Q9KYS3" FT /protein_id="CAB91128.1" FT /translation="MVTLAEVAQHAGVSASTVSYVLSGKRSISTTTRQRVEESIRKLGY FT HPNAGARALASSRSNIIALMIPLRTDMYVPVMMEIAIAVAAGARTHGYDILLLTGEEGP FT DAVRRVTGSGLADAMILMDVELDDERLPLLRDTHQPSVLIGLPADTEGLTCVDLDFRAT FT GALCVEHLAQLGHRDIAVIGEAAAVYERHTGFAERTLDGLRTRARELGLRLLHRPCEGG FT YDAMSATLARVFDERPDTTGFVVQNESAVEPLLALLRQQGRAVPEDVSVVAVCPEQVAT FT QASVRLTSVAVPAQEMGRRAVEQLVAKLDGRGSDEVVLLAPELTVRASSGPAPVRP" FT misc_feature complement(219625..220356) FT /note="Pfam match to entry PF00532 Peripla_BP_like, FT Periplasmic binding proteins and sugar binding domain of FT the LacI family., score 5.40, E-value 9.9e-06" FT misc_feature complement(220447..220527) FT /note="Pfam match to entry PF00356 lacI, Bacterial FT regulatory proteins, lacI family, score 35.70, E-value FT 1.3e-08" FT misc_feature complement(220462..220518) FT /note="PS00356 Bacterial regulatory proteins, lacI family FT signature" FT RBS complement(220533..220537) FT RBS 220808..220811 FT CDS 220820..222796 FT /transl_table=11 FT /gene="SCO5693" FT /gene_synonym="SC5H4.17" FT /product="putative acyl CoA dehydrogenase" FT /note="SC5H4.17, probable acyl CoA dehydrogenase, len: 658 FT aa; similar to SW:ACDV_BOVIN (EMBL:U30817) Bos taurus FT acyl-CoA dehydrogenase, very-long-chain specific precursor FT (EC 1.3.99.-) VlcaD, 655 aa; fasta scores: opt: 768 FT z-score: 864.8 E(): 0; 31.0% identity in 616 aa overlap . FT Contains 2x Pfam matches to entry PF00441 Acyl-CoA_dh, FT Acyl-CoA dehydrogenase" FT /db_xref="GOA:Q9KYS2" FT /db_xref="HSSP:1BUC" FT /db_xref="InterPro:IPR006092" FT /db_xref="UniProtKB/TrEMBL:Q9KYS2" FT /protein_id="CAB91129.1" FT /translation="MSAPPTPSSSPPSRPTVTEREARQVAEAAREQDWRKPSFAKELFL FT GRFRLDLLHPHPLPADQDVQRGEEFLAKLRDFCETKIDGAVIERDARIPDDVITGLKEL FT GAFGMKIDTKYGGLGLTQVYYNKALALVGSANAAIGALLSAHQSIGVPQPLKMFGTQEQ FT KDTFLPRCARTDISAFLLTEPDVGSDPARLATTAVRDGDDYVLDGVKLWTTNGVVADLL FT VVMARVPKPEGGKDAAGGKGGITAFVVEAASEGITVENRNAFMGLRGLENGVTRFHRVR FT VPAANRIGPEGAGLKIALTTLNTGRLSLPAMCVGAGKWCLKIAREWSAVREQWGKPVAL FT HEAVGSKISFIAATTFALEAVLDLSSQMADEDRNDIRIEAALAKLYGSEMACLMADELV FT QIRGGRGFETAASLEARGERAVPAEQLLRDLRINRIFEGSTEIMHLLIAREAVDAHLSV FT AGDLIDPDKTLSDKARAGAQAGVFYAKWLPKLVAGPGQLPRSYADFHPSGHPDLSSHLR FT YAERTARKLARSTFYAMSRWQGRMETKQGFLGRIVDIGAELFAMSAACVRAEHLRVKDD FT HGREAYQLADAFCRQSRIRVEELFGRLWSNTDDLDRKVVKGVLGGAYEWLEEGVVDPSG FT TGPWIAEAAPGPSRRENVRRAIG" FT misc_feature 221012..221836 FT /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA FT dehydrogenase, score 129.60, E-value 3.4e-37" FT misc_feature 221921..222166 FT /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA FT dehydrogenase, score 37.50, E-value 3.5e-10" FT CDS 222922..224178 FT /transl_table=11 FT /gene="SCO5694" FT /gene_synonym="dxr" FT /gene_synonym="SC5H4.18" FT /product="1-deoxy-D-xylulose 5-phosphate reductoisomerase" FT /note="SC5H4.18, dxr, 1-deoxy-D-xylulose 5-phosphate FT reductoisomerase, len: 418 aa; highly similar to FT SW:DXR_MYCTU (EMBL:Z74024) Mycobacterium tuberculosis FT 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC FT 1.1.1.-) (DXP reductoisomerase) Dxr or MTCY274.01c, 436 aa; FT fasta scores: opt: 1079 z-score: 1175.5 E(): 0; 52.3% FT identity in 396 aa overlap and to TR:CAB60758 FT (EMBL:AJ250714) Zymomonas mobilis 1-deoxy-D-xylulose FT 5-phosphate reductoisomerase Dxr, 388 aa; fasta scores: FT opt: 966 z-score: 1053.7 E(): 0; 44.0% identity in 389 aa FT overlap" FT /db_xref="GOA:Q9KYS1" FT /db_xref="HSSP:1K5H" FT /db_xref="InterPro:IPR013512" FT /db_xref="UniProtKB/Swiss-Prot:Q9KYS1" FT /protein_id="CAB91130.1" FT /translation="MSDSPAPLADPHLVYDPVAGDGPKDVVVLGSTGSIGTQAIDLVLR FT NPDRFRVTALSANGGRVALLAEQAYRLKARTVAVAREDVVPALREALTAQYGTGEPLPE FT ILAGPEAATQLAASDCHTVLNGITGSIGLAPTLAALEAGRTLALANKESLIVGGPLVKA FT LAKPGQIIPVDSEHAALFQALAAGTRADVRKLVVTASGGPFRGRTRDELAAVTVEDALA FT HPTWAMGPVITINSATLVNKGLEVIEAHLLYDIPFDRIEVVVHPQSYVHSMVEYTDGST FT LAHATPPDMGGPIAVGLGWPERVPDAAPAFDWSKASTWEFFPLDNEAFPSVDLARHVGQ FT LAGTAPAVFNAANEECVEAFRSGALPFLGIMETVTRVVEEHGTPRTGTSLTVADVLEAE FT TWARARARQLAAQTAEARA" FT CDS 224187..225479 FT /transl_table=11 FT /gene="SCO5695" FT /gene_synonym="SC5H4.19" FT /product="putative metalloprotease" FT /note="SC5H4.19, possible metalloprotease, len: 430 aa; FT similar to TR:O83609 (EMBL:AE001235) Treponema pallidum FT zinc protease, putative TP0600, 450 aa; fasta scores: opt: FT 181 z-score: 205.4 E(): 0.00056; 28.0% identity in 400 aa FT overlap. Contains Pfam match to entry PF00595 PDZ, PDZ FT domain (Also known as DHR or GLGF) and match to Prosite FT entry PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature and also possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q9KYS0" FT /db_xref="InterPro:IPR008915" FT /db_xref="UniProtKB/Swiss-Prot:Q9KYS0" FT /protein_id="CAB91131.1" FT /translation="MFILGIVLFAVGLLFSIAWHELGHLSTAKMFGIRVPQYMVGFGPT FT LFSKKKGDTEYGVKAIPFGGYIRMIGMFPPGPDGRMEARSTSPWRGMIEDARSAAFEEL FT QPGDEKRLFYTRKPWKRVIVMFAGPFMNLILAVVLFLTVLMGFGISQQTTTVSSVSQCV FT ISQSENPDDCAKSDPASPAAAAGLRAGDKILAFDGVRTDDWDKLSDLIRANPGEDVPVV FT VERKGEEITLHATIATNKVAKKDSNGQIVQGEYVTAGFLGFSSATGVVKQDFGQSVTWM FT GDRIGDAVDNLAALPAKIPALWDAAFGDGPREADSPMGVVGAARVGGEIATLDIPPTQQ FT LAMFVMLVAGFNLSLFLFNMLPLLPLDGGHIAGALWESLRRATAKVLRRPDPGPFDVAK FT LMPVAYVVAGVFVCFTLLVLVADVVNPVRIT" FT misc_feature 224235..224264 FT /note="PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature" FT misc_feature 224592..224864 FT /note="Pfam match to entry PF00595 PDZ, PDZ domain (Also FT known as DHR or GLGF)., score 4.90, E-value 0.42" FT CDS 225675..226832 FT /transl_table=11 FT /gene="SCO5696" FT /gene_synonym="gcpE" FT /gene_synonym="SC5H4.20" FT /product="hypothetical protein" FT /note="SC5H4.20, gcpE, hypothetical protein, len: 385 aa; FT highly similar to SW:GCPE_ECOLI (EMBL:X64451) Escherichia FT coli GcpE protein (protein E), 372 aa; fasta scores: opt: FT 1053 z-score: 1191.9 E(): 0; 45.4% identity in 366 aa FT overlap, to TR:O33350 (EMBL:AL008883) Mycobacterium FT tuberculosis GcpE, 387 aa; fasta scores: opt: 1970 z-score: FT 2224.9 E(): 0; 78.7% identity in 385 aa overlap and to FT TR:CAB39700 (EMBL:AL049485) Streptomyces colicolor FT hypothetical protein SC6A5.16, 384 aa; fasta scores: opt: FT 2348 z-score: 2424.0 E(): 0; 94.8% identity in 385 aa FT overlap" FT /db_xref="GOA:Q9KYR9" FT /db_xref="InterPro:IPR004588" FT /db_xref="UniProtKB/Swiss-Prot:Q9KYR9" FT /protein_id="CAB91132.1" FT /translation="MTAISLGMPDVPTRLAERRKSRQIQVGPVAVGGDAPVSVQSMTTT FT RTSDIGATLQQIAELTASGCQIVRVACPTQDDADALPVIARKSQIPVIADIHFQPKYVF FT AAIEAGCAAVRVNPGNIKQFDDKVKEIAKAAKDHGTPIRIGVNAGSLDRRLLQKYGRAT FT PEALAESALWEASLFEEHDFRDIKISVKHNDPVVMVEAYRQLAAQCDYPLHLGVTEAGP FT AFQGTIKSAVAFGALLSQGIGDTIRVSLSAPPVEEIKVGIQILESLNLRQRGLEIVSCP FT SCGRAQVDVYKLAEEVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIF FT VKGEVIKTVPESKIVETLIDEAMKIAEQMEKDGVTSGEPSVSVAG" FT stem_loop 226843..227028 FT /note="28617 AGGGGGTGTCGTTTGGCTCTTGCCGG 28642 28777 FT CCGGCCTGATCCAAACGGCACCCCCT 28802. Score 50: 22/26 (84%) FT matches, 0 gaps" FT CDS 227102..227965 FT /transl_table=11 FT /gene="SCO5697" FT /gene_synonym="SC5H4.21" FT /product="conserved hypothetical protein SC5H4.21" FT /note="SC5H4.21, hypothetical protein, len: 287 aa; similar FT to TR:O33349 (EMBL:AL008883) Mycobacterium tuberculosis FT hypothetical 30.3 kD protein MTV003.13c, 284 aa; fasta FT scores: opt: 798 z-score: 942.8 E(): 0; 48.0% identity in FT 269 aa overlap" FT /db_xref="GOA:Q9KYR8" FT /db_xref="InterPro:IPR016794" FT /db_xref="UniProtKB/TrEMBL:Q9KYR8" FT /protein_id="CAB91133.1" FT /translation="MRPPHVLTQTTSRVLEPSDLDAALAILDRDPVANAFVTARVQIAG FT LDPWRLGGEMWGWYEHGMLTSLCYAGANLVPICATQRAVRAFADRARRAGRRCSSIVGP FT AGPTAQLWRLLEPGWGPAREVRTHQPLMVADRLPDDMAPDPYVRRVRKDEVERIMPACV FT AMFTEEVGISPMAGDGGLLYQARVAELVGSGRSFARFDADGKVVFKAEIGAATDRACQI FT QGVWVAPEYRGKGLAAPGMAAVLRYALTDVAPVASLYVNDFNTAARRTYLRVGFQEVGA FT FMSVLF" FT CDS 228024..228566 FT /transl_table=11 FT /gene="SCO5698" FT /gene_synonym="SC5H4.22" FT /product="hypothetical protein SC5H4.22" FT /note="SC5H4.22, hypothetical protein, len: 180 aa; similar FT to TR:O69563 (EMBL:AL022602) Mycobacterium leprae FT hypothetical 23.9 kD protein MLCB268.13, 210 aa; fasta FT scores: opt: 243 z-score: 313.1 E(): 5.6e-10; 29.1% FT identity in 203 aa overlap" FT /db_xref="GOA:Q9KYR7" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9KYR7" FT /protein_id="CAB91134.1" FT /translation="MDLVIGPLDLSAHVDEALAVQAAAFGLGPDEVAVRRQIVLRHMTH FT PGARALGATVRGRLVGFVYGMPNDRTHWWSTVVEPYLRAQGTDAWLDDSFVITELHVHP FT SHQNRGAGRSLITTITDAATEPRSILSAIDTESPARGLYRSLGYQDLARRVLFPSAPKP FT YAVMGATLPLLRRTPGQ" FT CDS 228640..230343 FT /transl_table=11 FT /gene="SCO5699" FT /gene_synonym="proS" FT /gene_synonym="SC5H4.23" FT /product="prolyl tRNA synthetase" FT /note="SC5H4.23, proS, prolyl tRNA synthetase, len: 567 aa; FT highly similar to SW:SYP_ECOLI (EMBL:X55518) Escherichia FT coli prolyl-tRNA synthetase (EC 6.1.1.15) ProS, 572 aa; FT fasta scores: opt: 1403 z-score: 1520.4 E(): 0; 41.8% FT identity in 574 aa overlap. Contains Pfam match to entry FT PF00587 tRNA-synt_2b, tRNA synthetase class II (G, H, P, S FT and T) and match to Prosite entry PS00179 FT Aminoacyl-transfer RNA synthetases class-II signature 1" FT /db_xref="GOA:Q9KYR6" FT /db_xref="InterPro:IPR007214" FT /db_xref="UniProtKB/Swiss-Prot:Q9KYR6" FT /protein_id="CAB91135.1" FT /translation="MANAPVQRMSKLMAKTLRDDPADAEVLSHKLLVRAGYVRRTAAGL FT WSWLPLGKKVLGNIERIVREEMDAIGAQEVQLPALLPREPYEATGRWQEYGPELFRLQD FT RKGGDYLLGPTHEEIFTLLVKDQASSYKDLPVILYQIQNKYRDEARPRAGILRGREFLM FT KDSYSFDVADEGLAESYALHRAAYQRIFERLGLDYRIVAATAGAMGGSKSEEFLAPAEA FT GEDTFADCPNCDYAANTEAITFRLTPVDATDVPAAEDIPTPDTPTIETLAASLGVEASA FT TLKNLLVKVDGEIVAVGVPGDREVDMDKVEAHFAPAAVELVTAEDFVGRPDLVRGYVGP FT QGLGEKVTYIADPRVAPGTAWITGANKADTHAKNVVAGRDFEVDTYVDVVVVREGDPCP FT NCGTGLKLDRAIEIGHIFQLGRKYADALKLDVLGQNGKPARVTMGSYGIGVSRAVAALA FT EQHADDKGLVWSKEVAPADVHVVAAGKALQTELALEVSDKLAAAGVRVLVDDRAGVSPG FT VKFTDAELIGVPQILVAGRRSGEGVVELKDRRTGEREEVTVEEALTRLTS" FT misc_feature 229042..230301 FT /note="Pfam match to entry PF00587 tRNA-synt_2b, tRNA FT synthetase class II (G, H, P, S and T), score 25.90, FT E-value 9e-05" FT misc_feature 229072..229134 FT /note="PS00179 Aminoacyl-transfer RNA synthetases class-II FT signature 1" FT stem_loop 230731..230843 FT /note="32505 GGGGCCGTGTCGGGGGGTGTCCGCCC 32530 32592 FT GGACGGACACCCCCCGGCGCGGCCCC 32617. Score 57: 23/26 (88%) FT matches, 0 gaps" FT CDS complement(230917..231816) FT /transl_table=11 FT /gene="SCO5700" FT /gene_synonym="SC5H4.24c" FT /product="putative kinase" FT /note="SC5H4.24c, probable kinase, len: 299 aa; similar to FT SW:STRA_STRGA (EMBL:X05648) Streptomyces glaucescens FT streptomycin 6-kinase (EC 2.7.1.72) Sph, 307 aa; fasta FT scores: opt: 446 z-score: 504.5 E(): 1.2e-20; 34.7% FT identity in 271 aa overlap. Contains possible FT helix-turn-helix motif at residues 249..270 (+2.59 SD)" FT /db_xref="GOA:Q9KYR5" FT /db_xref="InterPro:IPR006748" FT /db_xref="UniProtKB/TrEMBL:Q9KYR5" FT /protein_id="CAB91136.1" FT /translation="MAFEPPRRLVRAFGETAPEGDDWLATLPEVAERAVARRGLTVERV FT QVPGGRSSLVVLVRTAEGAPAVLKLAPRRARPESERAALVHWGGRGAVQVREEGDEEGV FT LLLERLHPDVSVRSLPEAKALLEAAGTLRRLWVEPPGSHPFETVAERTGRQAEAMRAGA FT AADAQVAPLVDAALAARAELLGGPSEQRLLHGTFRQSKVLAGDRMPWLAVGPDPVVGES FT AFDLARLVRDRVEDLIAQPSGASTTRRRIKRLAESLEVDQERLRGWTLFRAVESGVRAR FT RVGRERDAELLLEFAGWL" FT CDS complement(231856..232359) FT /transl_table=11 FT /gene="SCO5701" FT /gene_synonym="SC5H4.25c" FT /product="hypothetical protein SC5H4.25c" FT /note="SC5H4.25c hypothetical protein, len: 167 aa; similar FT to TR:O05815 (EMBL:Z95207) Mycobacterium tuberculosis FT hypothetical 16.9 kDp protein MTCY24A1.13c, 162 aa; fasta FT scores: opt: 242 z-score: 266.6 E(): 2.2e-07; 38.9% FT identity in 144 aa overlap" FT /db_xref="GOA:Q9KYR4" FT /db_xref="UniProtKB/TrEMBL:Q9KYR4" FT /protein_id="CAB91137.1" FT /translation="MGKAGNGRLDALQAALAAEHAAVYGYGVVGGRIAEDRRAEARTAY FT DAHRARRDALAREVRDLGGEPVAAAAGYALPFSVPDSAAAVRLAAELEDRLAGVYSDLV FT RAAEGGGRTSAAGALREAAVRAVRWRGGSVAFPGLAERVGTPAGRSAAPGASDTATATA FT SPTA" FT CDS complement(232362..232925) FT /transl_table=11 FT /gene="SCO5702" FT /gene_synonym="SC5H4.26c" FT /product="putative lipoprotein" FT /note="SC5H4.26c, possible lipoprotein, len: 187 aa; FT similar to TR:O05816 (EMBL:Z95207) Mycobacterium FT tuberculosis hypothetical 17.7 kD protein MTCY24A1.14c, 181 FT aa; fasta scores: opt: 152 z-score: 161.9 E(): 0.15; 32.6% FT identity in 178 aa overlap. Contains possible N-terminal FT region signal peptide sequence and correctly situated match FT to Prosite entry PS00013 Prokaryotic membrane lipoprotein FT lipid attachment site" FT /db_xref="InterPro:IPR017909" FT /db_xref="UniProtKB/TrEMBL:Q9KYR3" FT /protein_id="CAB91138.1" FT /translation="MSLSPSPRLPRGPRRRSLLASAAGAALLAGCTGGPGSGEAGAGPS FT AVERARARAARDSEELAARYAAVIAAHPGLAERLRPLREEVVRHAEAFGGVRAASPTAS FT GTAAGTAASPSASVRAAGPANDSDGSDAVPTDEKGALALLAGAERKLAGRRTEALLDVP FT GEQARLLASVAAAGAAHVFLLTEG" FT RBS complement(232367..232371) FT misc_feature complement(232833..232865) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS complement(232934..232938) FT repeat_region 233012..233033 FT repeat_region 233012..233165 FT /note="7x degenerate repeat FT (C/A)(A/G)GC(G/A)GACC(A/G)(C/A)CGA(C/T)(G/C)A)(A/C)CGAG" FT repeat_region 233034..233055 FT repeat_region 233056..233077 FT repeat_region 233078..233099 FT repeat_region 233100..233121 FT repeat_region 233121..233143 FT repeat_region 233144..233165 FT RBS 233324..233329 FT CDS 233338..233871 FT /transl_table=11 FT /gene="SCO5703" FT /gene_synonym="SC5H4.27" FT /product="hypothetical protein SC5H4.27" FT /note="SC5H4.27, hypothetical protein, len: 177 aa; similar FT to TR:O05817 (EMBL:Z95207) Mycobacterium tuberculosis FT hypothetical 19.5 kD protein MTCY24A1.15, 183 aa; fasta FT scores: opt: 288 z-score: 348.5 E(): 6e-12; 37.2% identity FT in 148 aa overlap" FT /db_xref="HSSP:1IB8" FT /db_xref="InterPro:IPR003728" FT /db_xref="UniProtKB/Swiss-Prot:Q9KYR2" FT /protein_id="CAB91139.1" FT /translation="MSTTQSERLRELLEPLVASQGLDLEEIAVDSVGRRRVLSVVVDSD FT TGADLDRIADVSRALSAKLDETDAMGEGEYTLEVGTPGAERSLTQHRHYVRATDRLVRF FT QLREGGELVARILAVDEDGLDLEVPGVKGRRPTTRRLPFGDIDKARVQVEFNRKDTKND FT NQTEHDNKTEEEEA" FT RBS 233860..233866 FT CDS 233874..234896 FT /transl_table=11 FT /gene="SCO5704" FT /gene_synonym="SC5H4.28" FT /product="putative transcriptional FT termination/antitermination factor" FT /note="SC5H4.28, probable transcriptional FT termination/antitermination factor, len: 340 aa; highly FT similar to TR:Q9Z5J1 (EMBL:AL035472) Mycobacterium leprae FT putative transcriptional termination/antitermination factor FT NusA, 347 aa; fasta scores: opt: 1292 z-score: 1449.3 E(): FT 0; 60.8% identity in 344 aa overlap and similar to FT SW:NUSA_ECOLI (EMBL:X00513) Escherichia coli N utilization FT substance protein A (NusA protein) (L factor) NusA, 495 aa; FT fasta scores: opt: 621 z-score: 698.0 E(): 2e-31; 35.4% FT identity in 336 aa overlap. Contains Pfam matches to FT entries PF00575 S1, S1 RNA binding domain and PF00013 FT KH-domain, KH domain" FT /db_xref="GOA:Q9KYR1" FT /db_xref="HSSP:1K0R" FT /db_xref="InterPro:IPR003029" FT /db_xref="UniProtKB/TrEMBL:Q9KYR1" FT /protein_id="CAB91140.1" FT /translation="MDIDMSALRGLVREKEISFDLLVEAIESALLIAYHRTEGSRRHAR FT VELDRNTGHVTVWAKEDPDDLEEGQAAREFDDTPSDFGRIAATTAKQVILQRLRDAEDD FT ATLGEYAGREGDIVTGVVQQGRDPKNVLVDIGKLEAILPVQEQVPGETYPHGARLRSYV FT VRVAKGVRGPSVTLSRTHPNLVKKLFALEVPEIADGSVEISAIAREAGHRTKIAVRSTR FT SGLNAKGACIGPMGGRVRNVMGELNGEKIDIVDWSDDPAEMVANALSPARVSKVEVVDL FT AARSARVIVPDYQLSLAIGKEGQNARLAARLTGWRIDIRPDTEQPSDASPEQSSGGRGE FT " FT misc_feature 234204..234407 FT /note="Pfam match to entry PF00575 S1, S1 RNA binding FT domain, score 20.50, E-value 0.00046" FT misc_feature 234732..234890 FT /note="Pfam match to entry PF00013 KH-domain, KH domain, FT score 26.60, E-value 1.2e-06" FT RBS 234983..234987 FT CDS 234999..235304 FT /transl_table=11 FT /gene="SCO5705" FT /gene_synonym="SC5H4.29" FT /product="hypothetical protein" FT /note="SC5H4.29, hypothetical protein, len: 101 aa; similar FT to SW:YLXR_BACSU (EMBL:Z18631) Bacillus subtilis FT hypothetical 10.4 kD protein in NusA-InfB intergenic region FT (ORF3) YlxR, 91 aa; fasta scores: opt: 130 z-score: 176.4 FT E(): 0.023; 29.7% identity in 91 aa overlap. Contains and FT match to Prosite entry" FT /db_xref="InterPro:IPR007393" FT /db_xref="UniProtKB/TrEMBL:Q9KYR0" FT /protein_id="CAB91141.1" FT /translation="MSGRTRTRACPERTCVGCRERAVKSELLRTVAVEGHCTPDPRGTL FT PGRGAYVHPAPDCVDQAVRRKAFPRALRVPGPLDVKALRHYVEQAEGCSKVAESSM" FT RBS 235456..235461 FT CDS 235466..238567 FT /transl_table=11 FT /gene="SCO5706" FT /gene_synonym="SC9F2.10c" FT /gene_synonym="SC5H4.30" FT /product="probable translational initiation factor" FT /note="SC9F2.10c, probable translational initiation factor, FT partial CDS, len: >249aa; similar to the C-terminal region FT of many eg. SW:IF2_BACST translational initiation factor FT IF2 from Bacillus stearothermophilus (741 aa) fasta scores; FT opt: 788, z-score: 893.1, E(): 0, (51.2% identity in 248 aa FT overlap)." FT /note="SC5H4.30, probable translation initiation factor FT IF-2 (fragment), len: >835 aa; highly similar to FT SW:IF2_MYCLE (EMBL:AL035472) Mycobacterium leprae FT translation initiation factor IF-2 InfB, 924 aa; fasta FT scores: opt: 2559 z-score: 1220.5 E(): 0; 59.1% identity in FT 838 aa overlap and to SW:IF2_STIAU (EMBL:X87940) FT Stigmatella aurantiaca translation initiation factor IF-2 FT InfB, 1054 aa; fasta scores: opt: 1337 z-score: 648.2 E(): FT 1.2e-28; 38.8% identity in 891 aa overlap. Contains Pfam FT match to entry PF00009 GTP_EFTU, Elongation factor Tu FT family and match to Prosite entry PS00017 ATP/GTP-binding FT site motif A (P-loop)" FT /db_xref="GOA:Q8CJQ8" FT /db_xref="HSSP:1G7S" FT /db_xref="InterPro:IPR004161" FT /db_xref="UniProtKB/Swiss-Prot:Q8CJQ8" FT /protein_id="CAD55362.1" FT /translation="MAKVRVYELAKEFGVESKVVMAKLQELGEFVRSASSTIEAPVVRK FT LTDAFQQGGGNGRSAGRPAAPKKAAPRPSAPSPAQAGPSQAAPAAGDRAAAPRPSAAPK FT APAAQQPAAPSAPAPAPSQGPRPTPGPKPAPRPAPAAPEFTAPPAAPAAPSTPAPAPSG FT PKPGGARPGAPKPGGARPSGPGQDRGQQGGQGRPGGQRPGAPAQRPGGRPGGPRPGNNP FT FTSGGNAGMARPSAPRPQGGPRPGGPGGAPGGGPRPQGPGGQGGGPRPQAPGGNRPSPG FT SMPRPQGGGAGPRPGGGPRPNPGMMPQRPAAGPRPGPGGGGRGPGGAGRPGGGGGRPGG FT GGFAGRPGGGGGGRPGGGGGFAGRPGGGGGFGGGGGRPGFGGRPGGPGGRGGTQGAFGR FT PGGPARRGRKSKRQRRQEYEAMQAPSVGGVMLPRGNGETIRLSRGASLTDFAEKINANP FT ASLVAVMMNLGEMVTATQSVSDETLHLLAGEMNYTVQIVSPEEEDRELLESFDLEFGED FT EGSEEDLVVRPPVVTVMGHVDHGKTRLLDAIRKTNVIAGEAGGITQHIGAYQVATEVND FT EERKITFIDTPGHEAFTAMRARGARSTDIAILVVAANDGVMPQTVEALNHAKAAEVPIV FT VAVNKIDVEGADPTKVRGQLTEYGLVAEEYGGDTMFVDISAKQGLHIDSLLEAVVLTAD FT ASLDLRANPVQDAQGISIESRLDRGRGAVATVLVQRGTLRVGDTMVVGDAYGRVRAMLD FT DNGNNVAEAGPSTPVQVLGLTNVPGAGDNFIVVEEDRTARQIAEKRAARERNAAFAKRT FT RRVSLEDLDKVLKAGEVQQLNLIIKGDASGSVEALESSLLQLDVGEEVDIRVLHRGVGA FT VTESDIDLAMGSDAIVIGFNVRAAGRAAQMAEREGVDVRYYSVIYQAIEEIEAALKGML FT KPEYEEVELGTAEIREVFRSSKLGNIAGVLIRSGEVKRNTKARLLRDGKVIAENLNIEG FT LRRFKDDVTEIREGFEGGINLGNFNDIKVDDVIATYEMREKPRV" FT misc_feature 237041..237967 FT /note="Pfam match to entry PF00009 GTP_EFTU, Elongation FT factor Tu family, score 102.30, E-value 9.2e-27" FT misc_feature 237068..237091 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 238719..239012 FT /transl_table=11 FT /gene="SCO5707" FT /gene_synonym="SC9F2.09c" FT /product="small conserved hypothetical protein" FT /note="SC9F2.09c, small conserved hypothetical protein, FT len: 97aa; similar to eg. TR:O33252 (EMBL:Z97559) FT hypothetical protein from Mycobacterium tuberculosis (97 FT aa) fasta scores; opt: 397, z-score: 552.5, E(): 1.8e-23, FT (64.9% identity in 97 aa overlap)." FT /db_xref="InterPro:IPR007546" FT /db_xref="UniProtKB/TrEMBL:Q9Z526" FT /protein_id="CAB37476.1" FT /translation="MYVGTLSFDLLLGDVHSLKEKRSVVRPIVAELQRKYAVSAAEVEH FT MNLHRRAVVGLALVSGDAGHLSDVLDRCERLVAGRPEVELLSVRRRFHGDDD" FT CDS 239097..239579 FT /transl_table=11 FT /gene="SCO5708" FT /gene_synonym="SC9F2.08c" FT /product="putative ribosome-binding factor" FT /note="SC9F2.08c, possible ribosome-binding factor, len: FT 160aa; similar to many eg. SW:RBFA_ECOLI ribosome-binding FT factor, RbfA from Escherichia coli (132 aa) fasta scores; FT opt: 221, z-score: 268.0, E(): 1.3e-07, (36.1% identity in FT 119 aa overlap)." FT /db_xref="GOA:Q9Z527" FT /db_xref="HSSP:1KKG" FT /db_xref="InterPro:IPR020053" FT /db_xref="UniProtKB/Swiss-Prot:Q9Z527" FT /protein_id="CAB37475.1" FT /translation="MADNARAKRLADLIREVVAQKLQRGIKDPRLGSHVTITDTRVTGD FT LREATVFYTVYGDDEERKAATAGLESAKGILRSEVGKAAGVKFTPTLTFVMDALPDTAR FT NIEDLLDKARQSDEKVREASAGATYAGEADPYRKPDEDETDTEGAVEADETDDTAK" FT CDS 239576..240481 FT /transl_table=11 FT /gene="SCO5709" FT /gene_synonym="SC9F2.07c" FT /product="probable tRNA pseudouridine synthase" FT /note="SC9F2.07c, probable tRNA pseudouridine synthase, FT len: 301 aa; similar to many e.g. SW:TRUB_ECOLI tRNA FT pseudouridine synthase B from Escherichia coli (314 aa) FT fasta scores; opt: 357, z-score: 415.7, E(): 7.6e-16, FT (37.6% identity in 234 aa overlap)." FT /db_xref="GOA:Q9Z528" FT /db_xref="HSSP:1K8W" FT /db_xref="InterPro:IPR014780" FT /db_xref="UniProtKB/Swiss-Prot:Q9Z528" FT /protein_id="CAB37474.1" FT /translation="MTEKHTTPDGLVIVDKPSGFTSHDVVAKMRGIARTRRVGHAGTLD FT PMATGVLVLGVERATKLLGHLALTEKEYLGTIRLGQTTLTDDAEGEITGSRDASKVTWE FT AIDAGVAELSGDIMQVPSKVSAIKIKGVRSYKRAREGEEFEIPARPVTVSSFAVYDVRD FT AVADDGTPVLDLVVSVTCSSGTYIRALARDLGAGLGVGGHLTALRRTRVGPYKLDGART FT LDQLQQELTVMPVADAAGAAFPRWGVDARRARLLANGVRLEMPEEYTGVGAVAVFDPEG FT RLLALVEEHKGKAKSLAVFG" FT CDS 240737..244837 FT /transl_table=11 FT /gene="SCO5710" FT /gene_synonym="SC9F2.06c" FT /product="putative large Pro/Ala/Gly-rich protein" FT /note="SC9F2.06c, large Pro/Ala/Gly-rich protein of unknown FT function, len: 1366 aa" FT /db_xref="GOA:Q9Z529" FT /db_xref="InterPro:IPR000276" FT /db_xref="UniProtKB/TrEMBL:Q9Z529" FT /protein_id="CAB37473.1" FT /translation="MASRNRSREATGGRAGERSGDGSREARGGPPAVRAADPAEHGASD FT AALVRVHDLAGRPRGTGFLADHHGTVLTSHEAVDGLTRLVLSTAGGRRRVVAAADVVPL FT PALGLALVRTEGLGAAPLPLSTRDRVEAGTYVRIAAGGWREARVLGATDVTYTATDRFH FT LLGDALELAVGTCGRDALRLGGGAAGGPVLDVATGAVLGVLGTALSSGHSDVGFAVPLR FT RAAAGPLSDLLAENAATVPAYGADLNLAGVLALTATSVTEAVPDGGPDAREPVERAGVT FT REFAAFDTSGARVLGLVGAPGSGRTTELAALAARRSGGPAAAPTLWLRGADLHDDDMSL FT ADAARRTLDRAARTVAAPDPDGPGPVGLGDVTPERLAHLARTAGRPLLVALDGPEEMPP FT VLAHRLPEWTERTAAWLRETDTRLVVACRAEYWEHAGAEFPRELLHDPDPGAPSPGPTG FT AGAARRPTWAKEAPSPPASTAPEPWSGPGGAVGEAGGVSSPGTGLRGSGTVAAGGVPLF FT GARGGVSGAAGGVPLPTVFTASEPRPGPGGGLPPGAEVAVPGRGPEAAGGGSSQGIGVW FT EPGAGAAGGAPVFGARGVAFGAAAWPRRTGGAVGPRPAPGTAAGPSDGTDAVEGGPASA FT RRVTAGGARGRGQDGLLPCVRLGDLRDDEAREARARHGVLDGALADPDAGHPLTIRLLS FT EVRAALPGPPAPVPVTRDAVFTAYLDLMCLRVATRLADENGLRGTAVRRLAAKVSGQVH FT EAARRSLGPGQGGLDRESFETLFPCGPAPARLGGGTGWAPAVLAEGLFVPTGSGYRFAH FT EELADWIQGTHLDLGEALRALVHRRDTPLGTHTRTLPVPHHRIGSVVEALLLLARQHGV FT PQLALTLEELVHALDRDPHSWWAARLLAEALTRVPDATPYTDVLRLLADGIAERAGDGQ FT PTPQVFGPAFWTAPRVPAATRLDLLRRLVLADGPPHEPGPRHLDTAAGLLVADPRTVQP FT LLVRWFDDERPLPATPHATVATAAQALLHTHRHRGLDGLTEVLVDSTHRRADELLAVLA FT EEEPSALCRAVERWARDERPARHRAAVTHGLRTAPHARSGADRTLLRHAALVLLAGPSD FT SPLRGGALALLVQDPDCRDRHLPAALDLFAACDPYLPPSAVAAALPTHPEPVLEAFRAR FT LLGPDAGEALRRLADATTPALTHRVAALVGRTVTERPETAGHLAAYVDRRLDRDPAPRA FT VLLPLVTRLLDDGPEPARAALAGVLAADGATASAPLRRTLREHLYAHEHEPAVLDALLH FT AAARCDGAELRALVHRTGLLLVRTPEGATRYDRGLVDLARHLPGFAPRLTGWLTDAPED FT WAALVGPSTRRTIEHLAGVRVPA" FT CDS 244981..245937 FT /transl_table=11 FT /gene="SCO5711" FT /gene_synonym="SC9F2.05c" FT /product="probable riboflavin kinase (FAD synthetase)" FT /note="SC9F2.05c, probable riboflavin kinase (FAD FT synthetase), len: 318 aa; similar to many e.g. FT SW:RIBF_CORAM riboflavin kinase from Corynebacterium FT ammoniagenes (338 aa) fasta scores; opt: 801, z-score: FT 904.5, E(): 0, (45.4% identity in 326 aa overlap)" FT /db_xref="GOA:Q9Z530" FT /db_xref="HSSP:1N05" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/TrEMBL:Q9Z530" FT /protein_id="CAB37472.1" FT /translation="MQRWRGLEDIPEDWGRSVVTIGSYDGVHRGHQLIIRHAVDRAREL FT GVPAVVVTFDPHPSEVVRPGSHPPLLAPHHRRAELMADLGVDAVLILPFTKEFSKLSAA FT DFVVKVLVDRLRAKAVVEGPNFRFGHKAAGNVDFLIEQGKVYDFEVEVVDLYVTGDAGG FT GEPFSSTLTRRLVAEGDVAGAAEILGRPHRVEGVVVRGAQRGREMGFPTANVETLPHTA FT IPADGVYAGWLHAQGEAMPAAISVGTNPQFEGTERTVEAYAIDRVGLELYGLHVAVDFV FT AFVRGQAKFETLDALLEQMAVDVDRCREITATDAPRP" FT CDS complement(246052..247131) FT /transl_table=11 FT /gene="SCO5712" FT /gene_synonym="SC9F2.04" FT /product="putative peptide transport ATP-binding protein" FT /note="SC9F2.04, possible peptide transport ATP-binding FT protein, len: 359aa; similar to many eg. SW:APPF_BACSU FT oligopeptide transport ATP-binding protein from Bacillus FT subtilis (329 aa) fasta scores; opt: 798, z-score: 814.6, FT E(): 0, (41.2% identity in 330 aa overlap). Also similar to FT TR:O86575 (EMBL:AL031184) oligopeptide ABC transporter FT ATP-binding protein from Streptomyces coelicolor (496 aa) FT fasta scores; opt: 861, z-score: 875.6, E(): 0, (42.0% FT identity in 357 aa overlap). Contains PS00017 FT ATP/GTP-binding site motif A (P-loop) and PS00211 ABC FT transporters family signature. Also similar to the gene FT immediately upstream (SC9F2.03) suggesting a local FT duplication event fasta scores; opt: 722, z-score: 545.2, FT E(): 1.6e-25, (42.8% identity in 327 aa overlap). Also FT contains Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 212.90, E-value 4.7e-60." FT /db_xref="GOA:Q9Z531" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9Z531" FT /protein_id="CAB37471.1" FT /translation="MSSTLPDGAPDEAPGAVPDTAPDTAPDSAPPLLSVRGLHVTFPGR FT RGAAAARAVDGVDLDIRRGEIVALVGESGCGKTTLARSLLGLVRPTGGRVTFDGAPLGY FT SARALKAYRRRAQLVLQDPSGSLNPRHTVYDIVAEGLRIHGHAGDERTAVAEALSRAGL FT RPPERFFLRYPHELSGGQRQRVVIAGALVLQPELLVADEPVASLDASVRGEILALLLRL FT RTELGLSALVVTHDLGLAWNIADRVAVMYLGRIVETGAVEQVLTAPRHPYTQALLSVLP FT EAPGAPVVLTGEPPDPSYIPGGCRFHVRCPVLASGEAVRAGVADACRNEELEILRGGDE FT SQVACHWARAERPVAERAG" FT misc_feature complement(246373..246942) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 212.90, E-value 4.7e-60" FT misc_feature complement(246559..246603) FT /note="PS00211 ABC transporters family signature." FT misc_feature complement(246898..246921) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS complement(247128..248324) FT /transl_table=11 FT /gene="SCO5713" FT /gene_synonym="SC9F2.03" FT /product="putative peptide transport ATP-binding protein" FT /note="SC9F2.03, possible peptide transport ATP-binding FT protein, len: 393aa; similar to many (confirmed and FT proposed) eg. SW:OPPD_ECOLI oligopeptide transport FT ATP-binding protein from Escherichia coli (337 aa) fasta FT scores; opt: 870, z-score: 693.2, E(): 2.7e-31, (44.1% FT identity in 311 aa overlap).Contains PS00017 FT ATP/GTP-binding site motif A (P-loop) and PS00211 ABC FT transporters family signature. Also similar to the gene FT immediately downstream (SC9F2.04) suggesting a local FT duplication event fasta scores; opt: 722, z-score: 477.4, FT E(): 9.4e-22, (42.8% identity in 327 aa overlap). Also FT contains Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 197.30, E-value 2.3e-55." FT /db_xref="GOA:Q9Z532" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9Z532" FT /protein_id="CAB37470.1" FT /translation="MSLLEVRDLKVTYPGGAAAVRGVDLTLAAGEKLGVAGESGCGKST FT LALALLRLLPPGARVGGEILLDGEDVLTMKWGRVRAVRWAGASIVFQGAMHSLNAVHRV FT GDQIAEPILLHRRTTAAGARRRAGELLEQVGLPAARASAYPHELSGGQRQRVMIAMALA FT CDPRLIVADEPTTALDVMIQAQILRLIEGLVGEQDVGLIMISHDLAVLADTCDRLAVMY FT AGRVVEEGPARQVYDDARHPYGRALSEAFPTIGDPASRFAPRGLPGDPPDPAAVPSGCA FT FHPRCPVALDLCATQDQPLRDAGARRRAACVHVGPDGTVPPDGAGATAGSGPPEGDTAP FT AGDGAGSPAGRGEPAGTRDTGEGAEPAGGAADGRSGGDGRGAGGVAPAEDDGVRSSAP" FT misc_feature complement(247653..248237) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 197.30, E-value 2.3e-55" FT misc_feature complement(247839..247883) FT /note="PS00211 ABC transporters family signature." FT misc_feature complement(248193..248216) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS complement(248321..249274) FT /transl_table=11 FT /gene="SCO5714" FT /gene_synonym="SC9F2.02" FT /product="putative peptide transport permease" FT /note="SC9F2.02, possible peptide transport permease, len: FT 317aa; similar to many (confirmed and proposed) eg. FT SW:APPC_BACSU oligopeptide transport permease, AppC, from FT Bacillus subtilis (303 aa) fasta scores; opt: 638, z-score: FT 718.2, E(): 1.1e-32, (36.5% identity in 277 aa overlap). FT Contains probable membrane spanning hydrophobic regions. FT Also contains Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 42.30, E-value 1.1e-08." FT /db_xref="GOA:Q9Z533" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9Z533" FT /protein_id="CAB37469.1" FT /translation="MSAETTETTESTSGPPAKSGAPGPRALARRRRRASVARFWKEYRK FT HRAGVFGLATLVLFVLVALTAPLTVGSDVDSVTDAPGQPLESPSGRFPLGTDQFGRSLL FT GLLIWGSRVSLLVGLLAAVLSVLIGALIGITAGHFRGWYATVMMRITDWFLVMPTLVLA FT IVLATVLSRSLGTIVLAIGVTTWPTTARLVRAQTLAVESRPYIERAKALGGGHWHIMSR FT HVLPNVMPLILAQTTLIISSAILAEATLAFLGLGDPAVVSWGGLLQDAREAGSVSSGDW FT WYLVPPGIGIAVVALAFTLCGRAVEAVLNPRLGVSR" FT misc_feature complement(248459..248680) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 42.30, E-value 1.1e-08" FT CDS complement(249271..250227) FT /transl_table=11 FT /gene="SCO5715" FT /gene_synonym="SC3C3.01c" FT /gene_synonym="SC9F2.01" FT /product="putative peptide transport system permease" FT /note="SC3C3.01c, probable peptide transport system FT integral membrane protein, partial CDS, len: >229 aa; FT similar to many e.g. DPPB_ECOLI dipeptide transport system FT permease protein (339 aa), fasta scores; opt: 359 z-score: FT 654.6 E(): 3.3e-29, 35.3% identity in 238 aa overlap. Also FT similar to S. coelicolor SC2A11.12 (E(): 5.6e-12, 30.7% FT identity in 244 aa overlap)" FT /note="SC9F2.01, partial CDS, possible peptide transport FT system permease, len:>140aa; constitutes the C-terminal FT half of a CDS whose N-terminal region (TR:O86635) lies on FT Streptomyces coelicolor cosmid SC3C3 (EMBL:AL031231). FT Similar to many dipeptide transport system permeases FT (confirmed and proposed) eg. SW:DPPB_ECOLI dipeptide FT transport system permease, DppB, from Escherichia coli (339 FT aa) fasta scores; opt: 391, z-score: 499.6, E(): 1.6e-20, FT (43.8% identity in 137 aa overlap). Contains probable FT membrane spanning hydrophobic regions. Also contains Pfam FT match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 24.30, E-value 0.0029." FT /db_xref="GOA:Q8CJQ7" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q8CJQ7" FT /protein_id="CAD55363.1" FT /translation="MAGKLAGAAVSLFAVLVTSFFLFRLIPGDPVKFMTGGRPVSAEQL FT AVYREEFGLDLPLWEQFTDYCGKALSGDLGTSYQFHAPVVDKITEALPNTLLLTGTAFV FT LYTALGAFLGTRSAWRHGGLGDRLNTGLALTLYSIPSFWLGLLLIIVLSVGVDPIPGLF FT PTGGMESGREEGFAHVLDVAHHLVLPVVTLVAVEYGQTLLVTRSALLDEMGSDYLTTAR FT AKGLRDDLVRRRHAVPNALLPTVTLVFVNLGRTVAGVILVETVFSWPGLGGLFYQALSV FT PDLPLVQGLFFVFAAAVILMNTLADLLYPMLDPRVGR" FT misc_feature complement(249389..249606) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 24.30, E-value 0.0029" FT CDS complement(250310..252175) FT /transl_table=11 FT /gene="SCO5716" FT /gene_synonym="SC3C3.02c" FT /product="putative peptide transport system secreted FT peptide binding protein" FT /note="SC3C3.02c, probable peptide transport system FT secreted peptide binding protein, len: 621 aa; similar to FT e.g. DPPA_ECOLI periplasmic dipeptide transport protein FT precursor (535 aa), fasta scores; opt: 195 z-score: 391.5 FT E(): 1.5e-14, 26.4% identity in 550 aa overlap. Contains FT N-terminals signal sequence, possible membrane anchor at FT C-terminus and Pfam match to entry PF00496 SBP_bac_5, FT Bacterial extracellular solute-binding proteins, family 5, FT score 48.60, E-value 1.1e-11" FT /db_xref="GOA:O86636" FT /db_xref="InterPro:IPR000914" FT /db_xref="UniProtKB/TrEMBL:O86636" FT /protein_id="CAA20251.1" FT /translation="MNRHDQHGSGRTAHRPWRTRLLAAAGAGALLLASGAVAPSVAAKE FT GDGGDGGDKVLTVAVAQSVDSLSPFLAVRLLSTSIHRLTYEYLTNYDAKDNHVIPGLAT FT EWKSSPDKLTWTYTIRSDSKWSDGEQATAEDAAWTFNTMMTDPGAATANGSFVGNFAEV FT TAPSPTQLVIRLKKPQATMTALDVPIVPKHVWEKVDDFSKFNNDKDFPVVGNGPFVLTD FT YKPDSYVRLKANKDFWRGAPKFDELVFRYYKDQDAAVAALRKGEVSFVAGSPSLTPAQA FT DSLKGEENIRVNDAPGRRFYALATNPGARAKDGTRFGDGDPSLLDQRVRNALFMAVDRK FT AIVDKVFQGHAVEGAGYIPPRFSSYFFEPSGEQELAYDPAKAAQLLDEAGYRTDSDGKR FT LGKDGKPLDYRILCHATDPNDKAVGKYLQEWWGELGISVTLNCLDNVTDPWLAGKYDLA FT FDGWSVNPDPDFVLSIHTCAALPATPKDTGATDNFICDKKYDDLYARQLGEYDAGKRAA FT IVKQMQSRLYDTGYMNVMAYPNAVEAYRTDQIESITTMPSAAGNIYGQDGYWSWWSAVP FT ADSGDSSGGSSSTGTVIGIAAGVVVLVGLGVLFAVRRRASADDRE" FT misc_feature complement(250571..250717) FT /note="Pfam match to entry PF00496 SBP_bac_5, Bacterial FT extracellular solute-binding proteins, family 5, score FT 48.60, E-value 1.1e-11" FT RBS complement(252185..252189) FT /note="possible RBS upstream of SC3C3.02" FT CDS complement(252478..255729) FT /transl_table=11 FT /gene="SCO5717" FT /gene_synonym="SC3C3.03c" FT /product="conserved hypothetical protein SC3C3.03c" FT /note="SC3C3.03c, unknown, len: 1083 aa; contains three FT large Pro- and Pro-Gln rich regions: the segment between FT the central and C-terminal Pro-Gln rich regions is similar FT to hypothetical proteins from Mycobacteria which also FT contain Pro-rich domains; e.g. M. tuberculosis TR:E1264127 FT (EMBL:AL022120) RV3876 (666 aa), fasta scores; opt: 945 FT z-score: 387.0 E(): 2.7e-14, 31.2% identity in 693 aa FT overlap" FT /db_xref="UniProtKB/TrEMBL:O86637" FT /protein_id="CAA20252.1" FT /translation="MSSDRDGIRGGWATPGDDQPDAESSVETTGEFTIDYAPPAWYTQN FT ASGDGGQGESEGADPPGGSAGSPPASAPTAPPAPRGPVPPLPGLTPPPHATHHGPSYVP FT APAPGAPFTPPPPAPAPGAAFTPPPPPGPGAPFTPPAPPSGGPAGVPKLPVGSGFEPQP FT SPSQRSAPPEPEPEPEVRTPEPEPKAVAEPAPAADLASPAALPSFPAGGFQLQAPVPPP FT PAEEPGAAAEPEPEPDREPDTGDLDNGDLESGATMRFSAVALKREIAERAAAEDTAGEG FT PAAGADEARDTPDEPFVSTGFTDADTDAETDVDTESDFESVSDQAPDAESGGGHGDVAD FT PRLGGSAPDAEPEPEPESEPVVLAAVAESESESAERVGDEPEDSVPTADVPVDAVPDDA FT APPADSVPQDAVPQDATPPAPEGMPPLPPSYPPVAPAAAHQWPAQPQPPTQPQTAPAPP FT EQPGVAAQQPPFQPQAPQPAPAGWDAPPAPQPGYGFPQPGAQAPQPQPHSPAQPPGGYG FT FPQAPQAPHGPSPQQQPYPGVPQQQAPQAQGGGQAPPAQPGQPAQPGQPMQPGQPGQSG FT QPGQAPSAPQAAPHPPQAPPAQQPEYQPQAQQPQPQPQPQPYQQPADPRLGAAWPQPMQ FT HDQRQATNPGAAPLGYTAAVELSSDRLVNNKRQKAKSSRPAAGGSRFKLGGKKEEAERQ FT RKLDLIRTPVLSCYRIAVISLKGGVGKTTTTTALGSTLATERQDKILAIDANPDAGTLG FT RRVRRETGATIRDLVQAIPYLNSYMDIRRFTSQASSGLEIIANDVDPAVSTTFNDEDYR FT RAIDVLGQQYPIILTDSGTGLLYSAMRGVLDLADQLIIISTPSVDGASSASTTLDWLSA FT HGYADLVSRSITVISGVRETGKMIKVDDIVGHFQTRCRGVVVVPFDEHLSAGAEVDLDM FT MRPKVREAYFNLAAMVAEDFVRHQQSHGLWTSDGNPPPVAAPPMPGQQTPGQQMPGQPM FT PGQPMPGQQMPPQQGQPMPPQPGQPVPGQPYPPQPAPGQQQPYPQPGYNQPYAQPGYGY FT PQPGQPGHPGQPQQQPQQQQQPQQGQTPPPPPPQQ" FT RBS complement(255734..255739) FT /note="possible RBS upstream of SC3C3.03c" FT RBS 256198..256201 FT /note="possible RBS upstream of SC3C3.04" FT CDS 256208..257782 FT /transl_table=11 FT /gene="SCO5718" FT /gene_synonym="SC3C3.04" FT /product="putative secreted protein" FT /note="SC3C3.04, putative secreted protein, len: 524 aa; FT may contain N-terminal signal sequence with long leader" FT /db_xref="UniProtKB/TrEMBL:O86638" FT /protein_id="CAA20253.1" FT /translation="MSFGPPPSMSQSPSPAAEPFGARTAHGDAGGRGPRRSRKLLMGLL FT AVILTGALGTGGWMLWGRDSAGSQVSERTRTEVGQGPLDVRDTVEERQASINGTMAFRF FT SVDDMKPGEHVEMPGMWATDRILAKGINKTLVGMSIGPDAAPGDEKWRLALDGPICGYT FT RKVTGDNRTAVLFRANDWADEALCNQVAFVDLDDGRLLWQNRFSVSQLGRESSDATGTE FT KDRPGVALAHGTVAVTWGGGTIGYDMKGGATRWSTATTAPCQDMGVVGGRGLIVREYCW FT NGDPGPAGSWRDITYRLRKLDLATGAALWTYTAAEGIRSLHVPSVAPTVLAVSAGDTGI FT TDLISLDDQGHNRATISLRNGAYVAECSDTEYLMIDDCPTIAVGKEQVFIRSKDQLEEQ FT TYNWIIGFDLATGDTTKKFDSGPGALLQPVRMSGDRLLALRLSDDHIAPNALVALDPRT FT DEEVPFLYFGLPSEAQLMTMTDQNDIVVQDGRLFFGVKSANGPGDGKKKQWSYLVLGIG FT SVVPQKS" FT CDS complement(257820..258620) FT /transl_table=11 FT /gene="SCO5719" FT /gene_synonym="SC3C3.05c" FT /product="hypothetical protein SC3C3.05c" FT /note="SC3C3.05c, unknown, len: 266 aa" FT /db_xref="UniProtKB/TrEMBL:O86639" FT /protein_id="CAA20254.1" FT /translation="MSSLSTRPADGADGRARSEAGTGSSPGARRAPRRFLKGFGLLGPR FT HGAHTVPAVQLDALALPLGDDGVVIGVDAEGRPAVLGVNRPTPYDVVLIAGLWTAQVIA FT LRAAATGARVAVETGRPQAWVQLVHAMGGGQNGLAVYDVGRVPPQGASAGTPVLVVRDC FT GMRPPRGRVASGPWQSVLTLLPYLSPVAPRLMRQARLTGVQRVSPDEAAELGRVLALSR FT TETESLPSLADGMTLWCADRDRQYVMTQPTDGETGLLGTPRRMD" FT CDS complement(258617..259885) FT /transl_table=11 FT /gene="SCO5720" FT /gene_synonym="SC3C3.06c" FT /product="hypothetical protein SC3C3.06c" FT /note="SC3C3.06c, possible membrane protein, len: 422 aa; FT contains two possible transmembrane domains at N-terminus" FT /db_xref="UniProtKB/TrEMBL:O86640" FT /protein_id="CAA20255.1" FT /translation="MMASGTRTRNRGRTRAPNAAHLRARPGQGTSSRLQRLLLVELALA FT ALLVGWTVGKVAMVPAALLAVALVLIAFARRRGRSVPDWLSTARGLRHRLRRAGAVAIP FT PGTEPALVPALECEPALRTYSCGAHDRRPVGIVGDGTFVTAVVQVEADATALRAERSRQ FT PLPLRIVRDALAVDGIRLESAQIVLHTQPAPALHLPRQSVAVANYAPLQERTGTPAVRL FT TWVALKLDPELCPEAVAARGGGLVGAQKCVARAAHHLASRLTGAGFRTTVLREEELVTA FT LATSMCANPLVTAEAGRTEQRQPRTRESARSWRCDNRRHTTYWIRRWPHLGGDQSSSLP FT QFVADVTSVPALATTFSLRLSQAGQEVSVRGHLRVTGRSDDELVAARRALQDAARRSGI FT GLARLDREQLPGVLATLPLGGTR" FT RBS 260054..260057 FT /note="possible RBS upstream of SC3C3.07" FT CDS 260070..261596 FT /transl_table=11 FT /gene="SCO5721" FT /gene_synonym="SC3C3.07" FT /product="conserved hypothetical protein SC3C3.07" FT /note="SC3C3.07, unknown, len: 508 aa; similar to three FT hypothetical proteins from M. tuberculosis e.g. TR:O06317 FT (EMBL:Z95390) MTCY13E12.03C (470 aa), fasta scores; opt: FT 213 z-score: 330.7 E(): 3.7e-11, 28.0% identity in 508 aa FT overlap. Contains possible transmembrane domain at FT N-terminus" FT /db_xref="InterPro:IPR007795" FT /db_xref="UniProtKB/TrEMBL:O86641" FT /protein_id="CAA20256.1" FT /translation="MASRRDELNAYTFAKRRLLAAFLQPSPSGTEEGAPKPLRTVVPSL FT VAGALTLAVFGAWGMFQPTAPSGWDEPGARVIVGKQSTTRYVVLKTDGDTRLHPVLNLA FT SARLLMKDGTYEVVQVGDDVLDSGEIPRGPILGIPYAPDRLPAPEEAGRAKRWAVCEQP FT GGKGETVQEATFVLASQEAAKTEGAGRLKGGDTLYVATRTGERYLVDAEGSSYHVTGTE FT SDALTTALVGSRKPQLVTNEWLATLHQGDPIRFPPLPPAVGTPAGVSGALSAQENKVGT FT VLKTETGEGTKYYVVLPGKVQPITEFTAWLLITSPQTATLNMNGEARTVGLQDFTAEPD FT PFEGQPDDWPRQRVHQVNSASAGTGRDTVCSVLRKVDTEGDTTLSTWAGQQYPAEITSD FT GTSTHVTPGTGLLYTQIQGTGTDSGSLFLVTDTGLRYAVQANGDSDADRSDIGADGRKK FT TSDGSPEPSEAQVKLGYENVRPAKVPLAWSEFLAKGPRLDTNSARQPQGS" FT RBS 261653..261657 FT /note="possible RBS upstream of SC3C3.08" FT CDS 261668..262909 FT /transl_table=11 FT /gene="SCO5722" FT /gene_synonym="SC3C3.08" FT /product="serine protease (putative secreted protein)" FT /note="SC3C3.08, serine protease (putative secreted FT protein), len: 413 aa; almost identical to TR:Q53863 FT (EMBL:U33176) serine protease (390 aa), 98.4% identity in FT 387 aa overlap and similar to many e.g. ELYA_BACSP alkaline FT elastase yab precursor (378 aa), fasta scores; opt: 466 FT z-score: 512.6 E(): 2.7e-21, 36.3% identity in 281 aa FT overlap. Also similar to downstream putative serine FT protease, SC3C3.17c (E(): 5.2e-07, 35.0% identity in 383 aa FT overlap). Contains PS00136, PS00137 and PS00138 Serine FT proteases, subtilase family, aspartic acid, histidine and FT serine active sites and Pfam match to entry PF00082 FT subtilase, Subtilase family of serine proteases, score FT 214.90, E-value 1.2e-60. Contains possible N-terminal FT region signal peptide sequence and possible hydrophobic FT membrane spanning region at C-terminal region" FT /db_xref="GOA:O86642" FT /db_xref="HSSP:1MPT" FT /db_xref="InterPro:IPR000209" FT /db_xref="UniProtKB/TrEMBL:O86642" FT /protein_id="CAA20257.1" FT /translation="MQQPLTKAPTLAAAVLLTALSTCAPSVPSGYSAVDTREPLRLAGS FT GSCTFPSEQQFKARPWPLQRVLLDELWQGTRKGKGVRVAVIDTGVDDDNPQLTDAVDKA FT AGLDLLTKGKGGDPTHDEVGHGTKVAGIIAARPAEGTGFVGLAPGATVIPVRQNDADSS FT GDSDSMAAAIRHAVAKGADVVNISQDTTKPLAATSELAEAVREALAQGVVVVASAGNDG FT LDGKTKDTYPAAFEGVLAVASSDRNNERAAFSQPGDFVGVAAPGVDIVSTVPGGGQCTD FT SGTSFSAPFVAGVAVLLKEKYPDWTPAQIVTRIEQTAERSVNGHDDFVGWGVVDPVRAV FT QEADSGRPPSSPTPDPGVRSAEAPDVAPFSLAETPEERDRRYAVYGLSVGAVLVVLISG FT TGVVLRDLRRRRRP" FT misc_feature 261818..262627 FT /note="Pfam match to entry PF00082 subtilase, Subtilase FT family of serine proteases, score 214.90, E-value 1.2e-60" FT misc_feature 261914..261949 FT /note="PS00136 Serine proteases, subtilase family, aspartic FT acid active site" FT misc_feature 262040..262072 FT /note="PS00137 Serine proteases, subtilase family, FT histidine active site" FT misc_feature 262514..262546 FT /note="PS00138 Serine proteases, subtilase family, serine FT active site" FT CDS complement(262938..263234) FT /transl_table=11 FT /gene="SCO5723" FT /gene_synonym="SC3C3.09c" FT /gene_synonym="bldB" FT /product="putative regulator, BldB" FT /note="SC3C3.09c, possible regulator, BldB, len: 98 aa; FT identical to TR:Q53842 (EMBL:U28930) bldB (98 aa) and FT similar to S. coelicolor TR:Q53896 (EMBL:X60316) AbaA ORFD FT (75 aa), fasta scores; opt: 150 z-score: 201.9 E(): FT 0.00055, 47.4% identity in 57 aa overlap" FT /db_xref="InterPro:IPR007278" FT /db_xref="UniProtKB/TrEMBL:Q53842" FT /protein_id="CAA20258.1" FT /translation="MAQVPDEDVKARKERERDELYALDISGVEWHSAPGTEEHEERVEI FT AYLPDGAVAMRSSLDPETVLRYTEAEWRAFVLGARDGEFDLEPAPGDGGVVAE" FT misc_feature complement(262938..263579) FT /note="98.9% match to SC28930 U28930 Streptomyces FT coelicolor (bldB) gene, from 1 to 640" FT CDS 263538..263912 FT /transl_table=11 FT /gene="SCO5724" FT /gene_synonym="SC3C3.10" FT /product="hypothetical protein SC3C3.10" FT /note="SC3C3.10, unknown, len: 124 aa" FT /db_xref="InterPro:IPR010310" FT /db_xref="UniProtKB/TrEMBL:O86643" FT /protein_id="CAA20259.1" FT /translation="MVTATSASEEGQETMSVDYSDQDLTDLADKIRTFHTDVSSRVTSL FT NAVVDMIQGGWQGAAGKEFDSVQRGVNQHLKKLQDNLVDLEEVMRMSVKGFTQHEQDRV FT SEIRKVDNSYQVTSRITDLA" FT misc_feature 263626..264053 FT /note="99% match to SC33195 U33195 Streptomyces coelicolor FT truncated orfX near bldB gene, from 33 to 459." FT RBS 263935..263939 FT /note="possible RBS upstream of SC3C3.11" FT CDS 263949..264260 FT /transl_table=11 FT /gene="SCO5725" FT /gene_synonym="SC3C3.11" FT /product="hypothetical protein SC3C3.11" FT /note="SC3C3.11, unknown, len: 103 aa" FT /db_xref="InterPro:IPR010310" FT /db_xref="UniProtKB/TrEMBL:O86644" FT /protein_id="CAA20260.1" FT /translation="MSVNYDRTAVNYDTVTQAAIDVRKTTRELSEGLETLMRKVAAVAE FT TWQGEAKTAYGEIQRSSATEMDQMCQKLARIAQLLDDSVIGYQDTDKGNAARFRMLMG" FT CDS 264381..264860 FT /transl_table=11 FT /gene="SCO5726" FT /gene_synonym="SC3C3.12" FT /product="hypothetical protein SC3C3.12" FT /note="SC3C3.12, unknown, len: 159 aa" FT /db_xref="UniProtKB/TrEMBL:O86645" FT /protein_id="CAA20261.1" FT /translation="MDEVSPQEAFDAFIHARVYCERPEDSGFLTVVAPNPPAVDAPPRS FT RILDLVTTTDTAPAGPRVHVAGTARAVHGRRRVVLDNGRRPPRSAATGTRRMAGPGRRA FT RRTACLEGQAQFEDEHPVTSFLEGHGIAEESIEFRGRLEPVDRDGQDNGTEQTQK" FT CDS 264884..265486 FT /transl_table=11 FT /gene="SCO5727" FT /gene_synonym="SC3C3.13" FT /product="hypothetical protein SC3C3.13" FT /note="SC3C3.13, unknown, len: 200 aa" FT /db_xref="UniProtKB/TrEMBL:O86646" FT /protein_id="CAA20262.1" FT /translation="MTDKRFLFCRIWIAPEDTVEDWVPGKPAELDRLIKRLGGAAAHFR FT EGAEKLRKLNTDPCRARLSRSSARRSRNCPRNSMVPRTRSLRRASPYSPTAKCLRVQRL FT TRQILDHEAPTARDLSRQYARAVDDYYVAIKAGDTKLPTRPPETNPGRTAKAELIERIN FT SAQGEVTEAAGIAKRTLHKAAGRVVPEVTGFQSRRRR" FT CDS complement(265517..266155) FT /transl_table=11 FT /gene="SCO5728" FT /gene_synonym="SC3C3.14c" FT /product="putative secreted protein" FT /note="SC3C3.14c, probable secreted protein, len: 212 aa; FT contains N-terminal signal sequence" FT /db_xref="UniProtKB/TrEMBL:O86647" FT /protein_id="CAA20263.1" FT /translation="MTKLTVRRPLIVVVAAAVVAVGAGLAVWATAFRSDAKELRASETC FT NEGVFSANVEPLERLVSPDSSFTSEWSREVSDSSLLLTCSNSTSHASVKMTAELKDGSV FT KDWRTQLGGADTADGTRFDVGTEAFVWDKQAAVYVVCKPHSAGSSHTAGLKDPYLSILV FT SASGSVERDSETRRQDLAHLASRMFFEAQLQTGCQEDFIAPSGPPRLTD" FT RBS complement(266162..266165) FT /note="possible RBS upstream of SC3C3.14c" FT CDS complement(266184..268421) FT /transl_table=11 FT /gene="SCO5729" FT /gene_synonym="SC3C3.15c" FT /product="conserved hypothetical protein SC3C3.15c" FT /note="SC3C3.15c, hypothetical protein, len: 745 aa; FT similar to TR:Q9AFG1 (EMBL:AF349618) Streptomyces FT ansochromogenes AG2 protein, 760 aa; fasta scores: pt: 640 FT Z-score: 664.3 E(): 2.3e-29; 29.462% identity in 706 aa FT overlap" FT /db_xref="UniProtKB/TrEMBL:O86648" FT /protein_id="CAA20264.1" FT /translation="MAISYEQLRSADLSSLSDAVDAWRPLPGQFDTIARAFGSTVTKGL FT RDSDWKGEAATEALEKFDVVEKQMKSASDEAHDVHALLKSAFDAFQAAKDELKTIEKYV FT HEDKHLKMNEGRVYCDPSTAPQEQQAALQKGYLDSVHECNNRIQAALKSAEDADTALHW FT ALTMDANGKSRGFNTHSATSVKDAAEGRKEALREARAMVKLAELGDGMTTAQIERMNKV FT LSKYQGDPLFNEKFATGLGGKGALLFWAEMADPSKGGYSRVPYEHSKERLEQLKALQGN FT LGRTLASATHSDSKEMRAWEKEVIDLGSSSLDTSHAGNPYGFQVMSNLMRQGDYDTHFL FT DRYGKELIKADKRWDSPFSPSDFWMRNSEADLNFGAADDRGQDPMTGFMEALGHNPKAS FT VEFLSQEANFDYLTSDREWPSDGTGSKDTGASAGYRSLSHALESATTGHAYDTGPSTHM FT PAHTKEQADLMTKVVQGVADPGDDFKLHEGMEESFGQMASEYMPDIHRELSGGQAGGGT FT LEDLYPLSGAQATFGEQAVTRFMYELGQSPDGYKALNVGEALYTSELMGYHLANPDAYG FT ESTKNTIQQISASNSEVQGVLGLARQDSDLQKSAEGDAAFNKDMDKWKAWATTAANIGI FT GAGVSTVASPVAGAFAVAATEDLTGQMIDGLFPDPRDSSQEALFQSGKDWEKHKDSTLA FT AAQQAASAADLAHSSGLNQAEIESAVRDGHFQGNDRAHSVLREYRENQHKA" FT misc_feature 267734..267737 FT /note="end of true overlap with cosmid St9F2" FT CDS complement(268423..268845) FT /transl_table=11 FT /gene="SCO5730" FT /gene_synonym="SC3C3.16c" FT /product="hypothetical protein SC3C3.16c" FT /note="SC3C3.16c, unknown, len: 140 aa" FT /db_xref="UniProtKB/TrEMBL:O86649" FT /protein_id="CAA20265.1" FT /translation="MSFDEMWGQARNAAAARRHSSMQLNQLAPVDAGGGSSPSLHVDAG FT VLEERATKADTVRTNFKDADNKVMTATGRVELKGFKSDSALSTFQKRWRSQMQYMDDLL FT GKGVAGNLRTSAAEFRKEEDKRRRAAKRENDSDGKK" FT CDS complement(268911..270263) FT /transl_table=11 FT /gene="SCO5731" FT /gene_synonym="SC3C3.17c" FT /product="putative secreted serine protease" FT /note="SC3C3.17c, possible secreted serine protease, len: FT 450 aa; similar in part to many e.g. SUBT_BACSU subtilisin FT E precursor (381 aa), fasta scores; opt: 321 z-score: 359.3 FT E(): 9.4e-13, 32.3% identity in 294 aa overlap. Also FT similar to downstream serine protease, SC3C3.08 (E(): FT 7.1e-07, 35.0% identity in 383 aa overlap). Contains FT N-terminal signal sequence, possible transmembrane domain FT at C-terminus and Pfam match to entry PF00082 subtilase, FT Subtilase family of serine proteases, score 151.00, E-value FT 2.1e-41" FT /db_xref="GOA:O86650" FT /db_xref="HSSP:1DBI" FT /db_xref="InterPro:IPR000209" FT /db_xref="UniProtKB/TrEMBL:O86650" FT /protein_id="CAA20266.1" FT /translation="MRASSRRNMRPASVLSAGLGLLLVGVAAAPAHAESVRDLQWHLDA FT MHAEEMWKVSTGRGITVAVIDTGVDDSLPDLKGQVLKGKDYSDQPGDERTDHEGHGTGM FT AALIAGTGKHGSKSGAYGLAPGVEILPIRMPEKIEGLDFTSGHNAARDFSKAIRFAADS FT DAKVINISMGQAESGTKGGVDTSELDAAVKYAVDKGKLIFAAAGNEGDGANRPRFPAST FT PGVVAVGSINEKVKRSSFSEWGPEIDVTAPGEDLVHACIGGTGVCRTSGTSDATAIASA FT SAALVWSKHPTWTNNQVLRVLINTMKGNEEEWTHNESFGYGIVRPRVALQNPGDPGPAD FT EYPLPDLAAAAASKSPSPEASPSGDAAENPAGGTYQAAASTSEDDSSTSLWIALGVAAA FT VVVGAAITFAVLRTRRRRVEQPTAPGSPATPAYAPPQQYPPHGTPGSGQRD" FT misc_feature complement(269349..270179) FT /note="Pfam match to entry PF00082 subtilase, Subtilase FT family of serine proteases, score 151.00, E-value 2.1e-41" FT CDS complement(270294..271847) FT /transl_table=11 FT /gene="SCO5732" FT /gene_synonym="SC3C3.18c" FT /product="hypothetical protein SC3C3.18c" FT /note="SC3C3.18c, unknown, len: 517 aa; C-terminus is FT Gly-Pro-rich, and is predicted to be non-coding by FT FramePlot" FT /db_xref="UniProtKB/TrEMBL:O86651" FT /protein_id="CAA20267.1" FT /translation="MGEQPGPRQPKLARTDFESMTHEQLAALLDSASPESASHLATKLT FT KAASTITKIGDDLMTHTKGLEWQGEAGDTFRDWGGQAASSTLRLGQYAEVASRWMATVA FT QAVVEAKAALPDTSETTQAKADLAAAKKTLAATQEPGARNDPDARKLAQTAQSDATTAQ FT QRMEAARGEAIQQLRKLAQTYEYSAQQVNSVEPPTFSPPSTHFGDTDWKPGEYISVPSH FT GASGAGGGSGTPAVVQGGQDSGSRVGAQPHPYSGASEGASPGLSSASADSRRPVAMDID FT GLTTLPERPGPTPQPGPNTPLPRSDAPPGQPVVGPPVLQNSGGGTNNPASGRMPVVPRP FT PLPPSQGPGSGGVRVPPLRDSGIVGGKPVTPTTGRPSGGIPRGTVIGGQGPEGRAPMVR FT GLTPGLPGGTGGSGQGGTIGSRRLASQTGGMTGAVAGQNGRLPMGRPMTPGGTGLPRPA FT SSSQSPRAAVLGRPTGGVPRTGGTGSRQQDQRGTDRPDYLSEDEETWQRGRRSLPPVVE FT " FT CDS complement(271847..272335) FT /transl_table=11 FT /gene="SCO5733" FT /gene_synonym="SC3C3.19c" FT /product="hypothetical protein SC3C3.19c" FT /note="SC3C3.19c, unknown, len: 162 aa" FT /db_xref="UniProtKB/TrEMBL:O86652" FT /protein_id="CAA20268.1" FT /translation="MGSNGGGTPDTGTSFDNLSHVNPAMALDIQHDAMKGFKKRVDELL FT LELDRSEAAPGKVGQDKLTRAHLGSAEFKEAQFLYDSYAVVHEELEKLSKALSAQIEGM FT GLAVHASRVGYENLDGDIRARMRAVNAEAEKYYVAGRDPYADRRGGPPPESDSSDEGL" FT RBS complement(271855..271858) FT /note="p |