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EBI DbfetchID AL939123; SV 1; linear; genomic DNA; STD; PRO; 300100 BP. XX AC AL939123; AL031184; AL035569; AL079356; AL137242; AL138978; AL157916; AC AL359152; AL359214; AL391588; AL391763; AL589707; XX DT 25-OCT-2002 (Rel. 73, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 4) XX DE Streptomyces coelicolor A3(2) complete genome; segment 20/29 XX KW . XX OS Streptomyces coelicolor OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Streptomycineae; Streptomycetaceae; Streptomyces. XX RN [1] RP 1-300100 RA Bentley S.D.; RT ; RL Submitted (09-MAY-2002) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Streptomyces sequencing team, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL sdb@sanger.ac.uk XX RN [2] RX DOI; 10.1038/417141a RX PUBMED; 12000953. RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L., RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H., RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E., RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D., RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.; RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor RT A3(2)"; RL Nature 417(6885):141-147(2002). XX DR EMBL-CON; AL645882. DR RFAM; RF00504; Glycine. XX FH Key Location/Qualifiers FH FT source 1..300100 FT /organism="Streptomyces coelicolor" FT /strain="A3(2)" FT /mol_type="genomic DNA" FT /db_xref="taxon:1902" FT RBS 53..56 FT CDS 66..1151 FT /transl_table=11 FT /gene="SCO5222" FT /gene_synonym="SC7E4.19" FT /product="putative lyase" FT /note="SC7E4.19, possible lyase, len: 361 aa; similar to FT SW:PTLS_STRSQ (EMBL:U05213) Streptomyces sp. pentalenene FT synthase (EC 4.6.1.5), 336 aa; fasta scores: opt: 254 FT z-score: 317.5 E(): 3.3e-10; 23.8% identity in 311 aa FT overlap. Contains match to Prosite entry PS00904 Protein FT prenyltransferases alpha subunit repeat signature and a TTA FT leucine codon, possible target for bldA regulation" FT /db_xref="GOA:Q9K499" FT /db_xref="InterPro:IPR008949" FT /db_xref="UniProtKB/Swiss-Prot:Q9K499" FT /protein_id="CAB94607.1" FT /translation="MHAFPHGTTATPTAIAVPPSLRLPVIEAAFPRQLHPYWPKLQETT FT RTWLLEKRLMPADKVEEYADGLCYTDLMAGYYLGAPDEVLQAIADYSAWFFVWDDRHDR FT DIVHGRAGAWRRLRGLLHTALDSPGDHLHHEDTLVAGFADSVRRLYAFLPATWNARFAR FT HFHTVIEAYDREFHNRTRGIVPGVEEYLELRRLTFAHWIWTDLLEPSSGCELPDAVRKH FT PAYRRAALLSQEFAAWYNDLCSLPKEIAGDEVHNLGISLITHHSLTLEEAIGEVRRRVE FT ECITEFLAVERDALRFADELADGTVRGKELSGAVRANVGNMRNWFSSVYWFHHESGRYM FT VDSWDDRSTPPYVNNEAAGEK" FT misc_feature 327..356 FT /note="PS00904 Protein prenyltransferases alpha subunit FT repeat signature" FT misc_feature 948..950 FT /gene="none" FT /note="TTA leucine codon. Possible target for bldA FT regulation" FT CDS 1148..2533 FT /transl_table=11 FT /gene="SCO5223" FT /gene_synonym="SC7E4.20" FT /product="putative cytochrome P450" FT /note="SC7E4.20, probable cytochrome P450, len: 461 aa; FT similar to SW:CP51_HUMAN (EMBL:U23942) Homo sapiens FT cytochrome P450 51 (EC 1.14.14.1) Cyp51, 503 aa; fasta FT scores: opt: 532 z-score: 587.2 E(): 3.1e-25; 25.7% FT identity in 447 aa overlap. Contains Pfam match to entry FT PF00067 p450, Cytochrome P450" FT /db_xref="GOA:Q9K498" FT /db_xref="InterPro:IPR002401" FT /db_xref="PDB:3DBG" FT /db_xref="UniProtKB/TrEMBL:Q9K498" FT /protein_id="CAB94608.1" FT /translation="MTVESVNPETRAPAAPGAPELREPPVAGGGVPLLGHGWRLARDPL FT AFMSQLRDHGDVVRIKLGPKTVYAVTNPELTGALALNPDYHIAGPLWESLEGLLGKEGV FT ATANGPLHRRQRRTIQPAFRLDAIPAYGPIMEEEAHALTERWQPGKTVDATSESFRVAV FT RVAARCLLRGQYMDERAERLCVALATVFRGMYRRMVVPLGPLYRLPLPANRRFNDALAD FT LHLLVDEIIAERRASGQKPDDLLTALLEAKDDNGDPIGEQEIHDQVVAILTPGSETIAS FT TIMWLLQALADHPEHADRIRDEVEAVTGGRPVAFEDVRKLRHTGNVIVEAMRLRPAVWV FT LTRRAVAESELGGYRIPAGADIIYSPYAIQRDPKSYDDNLEFDPDRWLPERAANVPKYA FT MKPFSAGKRKCPSDHFSMAQLTLITAALATKYRFEQVAGSNDAVRVGITLRPHDLLVRP FT VAR" FT misc_feature 1217..2428 FT /note="Pfam match to entry PF00067 p450, Cytochrome P450, FT score 221.80, E-value 1e-62" FT CDS complement(2547..3515) FT /transl_table=11 FT /gene="SCO5224" FT /gene_synonym="SC7E4.21c" FT /product="putative araC-family transcriptional regulator" FT /note="SC7E4.21c, probable araC-family transcriptional FT regulator, len: 322 aa; similar to TR:Q9S166 FT (EMBL:AB023785) Streptomyces griseus transcriptional FT activator for strR, AdpA, 405 aa; fasta scores: opt: 1005 FT z-score: 1177.5 E(): 0; 49.2% identity in 325 aa overlapand FT to TR:CAB87229 (EMBL:AL163641) Streptomyces coelicolor FT araC-family transcriptional regulator AdpA, 398 aa; fasta FT scores: opt: 990 z-score: 1160.1 E(): 0; 48.9% identity in FT 313 aa overlap. Contains Pfam match to entry PF00165 FT HTH_AraC, Bacterial regulatory helix-turn-helix proteins, FT araC family and match to Prosite entry PS00041 Bacterial FT regulatory proteins, araC family signature. Contains also a FT possible helix-turn-helix motif at residues 230..251 (+3.72 FT SD)" FT /db_xref="GOA:Q9K497" FT /db_xref="InterPro:IPR018062" FT /db_xref="UniProtKB/TrEMBL:Q9K497" FT /protein_id="CAB94609.1" FT /translation="MLRNVAAVLLDGAHPFELGVVCEVFGIDRSDEGLPVYDFAVVSAE FT GPTLGTHVGGLTVSTPYGLERLEEADLIAVPAGSDFVRREYPPDLLDALRRATDRGTRV FT LSVCSGVFVLGAAGLLDGRQCAVHWHHAAELARQHPRARVAPDVLYVDEDPVVTSAGTA FT AGIDACLHIVRKEQGPEVANRIARRMVVPPHRDGGQAQYIERPLPRSSCDTVGEVLAWM FT EQHLDEEVTVEQLAVRAHMSPRTFARRFQQETGTTPYRWILRQRVLLAQRLLEATDETM FT DTIAWRAGFGTAAALRHQFTRALDTTPHAYRRTFRGPEAAA" FT misc_feature complement(2571..2831) FT /note="Pfam match to entry PF00165 HTH_AraC, Bacterial FT regulatory helix-turn-helix proteins, araC family, score FT 79.70, E-value 6e-20" FT misc_feature complement(2592..2720) FT /note="PS00041 Bacterial regulatory proteins, araC family FT signature" FT misc_feature complement(3557..7543) FT /note="previously sequenced DNA fragment. EMBL:AJ276618 FT Streptomyces coelicolor A3(2) nrdX gene, nrdL gene and nrdM FT gene" FT CDS complement(3787..4818) FT /transl_table=11 FT /gene="SCO5225" FT /gene_synonym="nrdM" FT /gene_synonym="SC7E4.22c" FT /product="ribonucleotide-diphosphate reductase small chain" FT /note="SC7E4.22c, nrdM, ribonucleotide-diphosphate FT reductase small chain, len: 343 aa; identical to previously FT sequenced TR:CAB82486 (EMBL:AJ276618) Streptomyces FT coelicolor A3(2) ribonucleotide-diphosphate reductase small FT chain (EC 1.17.4.1) NrdM, 343 aa. Contains Pfam match to FT entry PF00268 ribonuc_red, Ribonucleotide reductases and a FT possible hydrophobic membrane spanning region" FT /db_xref="GOA:Q9K3C2" FT /db_xref="HSSP:1JK0" FT /db_xref="InterPro:IPR000358" FT /db_xref="UniProtKB/TrEMBL:Q9K3C2" FT /protein_id="CAB94610.1" FT /translation="MTTETPAHPTTKNLLDPGFELTLRPMRYPDFYERYRDAIKNTWHV FT EEVDLHSDVADLAKLSPMEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLS FT RQLFEEAVHVQFYLTLLDTYLPDPEDRAAAFAAVENIPSIREKAEFCFRWMDSVESIDR FT LETKADRRRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMH FT MSFAFDVVDTVRKEEPELFDDQLREQVTDMLREAVEAELQFARDLCGDGLPGMNTDSMR FT QYLECVADQRLTRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGTVDLS FT EDF" FT misc_feature complement(3832..4692) FT /note="Pfam match to entry PF00268 ribonuc_red, FT Ribonucleotide reductases, score 222.30, E-value 1e-75" FT CDS complement(4818..7193) FT /transl_table=11 FT /gene="SCO5226" FT /gene_synonym="nrdL" FT /gene_synonym="SC7E4.23c" FT /product="ribonucleotide-diphosphate reductase large chain" FT /note="SC7E4.23c, nrdL, ribonucleotide-diphosphate FT reductase large chain, len: 791 aa; identical to previously FT sequenced TR:CAB82485 (EMBL:AJ276618) Streptomyces FT coelicolor A3(2) ribonucleotide-diphosphate reductase large FT chain (EC 1.17.4.1) NrdL, 791 aa. Contains Pfam match to FT entry PF00317 ribonucleo_red, Ribonucleotide reductase and FT match to Prosite entry PS00089 Ribonucleotide reductase FT large subunit signature" FT /db_xref="GOA:Q9K496" FT /db_xref="InterPro:IPR002057" FT /db_xref="UniProtKB/TrEMBL:Q9K496" FT /protein_id="CAB94611.1" FT /translation="MTIAPADPASATPVTATGEPDGPGAALLRTLTGLTADLPGADPGR FT VAAAALRGRSARADEAELRELATEAAAGLISEDPVYSRLAARLLTIGIRAEAASQGVVT FT FTDSVATGHREGLIADRTAAFVRLHADRLDALIDQDADDRFGYFGLRTLYSRYLLRHPI FT TRKAVETPQHFLLRVAAGLAEDDTVRAADEVAALYGLMSRLDYLPSSPTLFNSGTRHAQ FT MSSCYLLDSPKDELDSLYDRLHQVARLSKHAGGIGIAYSRVRARGSLIRGTNGHSNGIV FT PFLKTLDASVAAVNQGGRRKGAAAVYLETWHADVEEFLELRDNTGEDARRTHNLNLAHW FT IPDEFMRRVDADGTWSLFSPADVPELTDLWGEEFDAAYRRAEEAGLARRTLPARELYGR FT MMRTLAQTGNGWMTFKDTANRTANQTATPGHVVHSSNLCTEILEVTDDGETAVCNLGSV FT NLGAFVDPAHGDMDWERLDATVRTAVTFLDRVVDINFYPTEQAGRSNARWRPVGLGAMG FT LQDVFFQLRLPFDSPEAKALSTRIAERIMLAAYETSADLAERNGPLPAWEKTRTARGVL FT HPDHYGVEPAWPERWAALRARMATTGLRNSLLLAIAPTATIASIAGVYECIEPQVSNLF FT KRETLSGEFLQVNSYLVDDLKRLGVWDARTREALREANGSVQGFTWIPEDVRALYRTAW FT EIPQRGLIDMAAARTPYLDQAQSLNLFLETPTIGKLSSMYAYAWKQGLKTTYYLRSRPA FT TRIARAAARATTVPVQAAPDPEAVACSLENPESCEACQ" FT RBS complement(4829..4832) FT misc_feature complement(4953..6791) FT /note="Pfam match to entry PF00317 ribonucleo_red, FT Ribonucleotide reductase, score 723.60, E-value 7.5e-271" FT misc_feature complement(5355..5423) FT /note="PS00089 Ribonucleotide reductase large subunit FT signature" FT CDS complement(7190..7465) FT /transl_table=11 FT /gene="SCO5227" FT /gene_synonym="nrdX" FT /gene_synonym="SC7E4.24c" FT /product="putative redoxin" FT /note="SC7E4.24c, nrdX, putative redoxin, len: 91 aa; FT identical to previously sequenced TR:CAB82484 FT (EMBL:AJ276618) Streptomyces coelicolor A3(2) putative FT redoxin NrdX, 91 aa. Doubtful CDS: Frameplot and FT Correlation Scores indicate that this CDS might not be a FT gene" FT /db_xref="UniProtKB/TrEMBL:Q9K3B9" FT /protein_id="CAB94612.1" FT /translation="MLMLAVAAGESGANPELSRNGVLACIRTSSHVRARLSSPRTCRQC FT ARPPWPGCHDVRASRSGPVDATPRALVSCPLPSLRRAPCRARECST" FT RBS complement(7202..7205) FT CDS complement(7544..8050) FT /transl_table=11 FT /gene="SCO5228" FT /gene_synonym="SC7E4.25c" FT /product="putative acetyltransferase" FT /note="SC7E4.25c, possible acetyltransferase, len: 168 aa; FT similar to TR:Q9S2P7 (EMBL:AL096872) Streptomyces FT coelicolor putative acetyltransferase SC5F7.12c, 169 aa; FT fasta scores: opt: 151 z-score: 187.3 E(): 0.0058; 36.2% FT identity in 141 aa overlap. Contains Pfam match to entry FT PF00583 Acetyltransf, Acetyltransferase (GNAT) family" FT /db_xref="GOA:Q9K495" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9K495" FT /protein_id="CAB94613.1" FT /translation="MDFVIRRATAEEYDTLGEITAQAYLRDGLLDFGESDSYLDELRDV FT AKRAAAAEVLVAVADDAVLGGATFVPSGGPMADIARPGEAEIRMLAVAREARGRGAGEA FT LVRACADRARAVPGCTGVVLSTQAAMRTAHRLYERLGFVRTPDRDWNPLPELDDIMLLT FT YELTL" FT misc_feature complement(7622..8038) FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 67.20, E-value FT 3.4e-16" FT CDS complement(8123..9721) FT /transl_table=11 FT /gene="SCO5229" FT /gene_synonym="SC7E4.26c" FT /product="putative permease" FT /note="SC7E4.26c, probable permease, len: 4532 aa; similar FT to TR:Q47552 (EMBL:L01152) Escherichia coli proline FT permease (fragment) PutP, 489 aa; fasta scores: opt: 333 FT z-score: 378.7 E(): 1.3e-13; 23.8% identity in 495 aa FT overlap. Contains Pfam match to entry PF00474 SSF, FT Sodium:solute symporter family. Contains also possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9K494" FT /db_xref="InterPro:IPR001734" FT /db_xref="UniProtKB/TrEMBL:Q9K494" FT /protein_id="CAB94614.1" FT /translation="MNGVALAVFIFFFVLVTAMGFLAARWRRAENEHSLDEWGLGGRSF FT GTWVTWFLLGGDLYTAYTFVAVPAAIYAAGASGFFAVPYTILVYPLIFTFLPRLWSVSH FT KHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGGEDTN FT WFVKDLPLLIAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGGFDDI FT FASASDKFTAAGKGGVVPDAGGQWTYATLALGSALALFMYPHSITATLSSRSREVIRRN FT TTILPLYSLMLGLLALLGFMAIAAGVKVDNGQLAIPQLFENMFPDWFAGVAFAAIGIGA FT LVPAAIMSIAAANLFTRNIYKDFIKPDATPQQETKVSKLVSLLVKVGALIFVLGMDKTV FT AINFQLLGGIWILQTFPALVGGLFTRWFHRWALLGGWAVGMVYGTVAAYGVASPTQKHF FT GGSSDEIPGIGEIGYIGLTAFVLNVLVTVVLTFVLRAVKAPDGVDETRPSDYTADAGDP FT GVQVELPPATAGSSH" FT misc_feature complement(8405..9604) FT /note="Pfam match to entry PF00474 SSF, Sodium:solute FT symporter family, score -80.90, E-value 5.6e-05" FT CDS complement(9730..10014) FT /transl_table=11 FT /gene="SCO5230" FT /gene_synonym="SC7E4.27c" FT /product="putative integral membrane protein" FT /note="SC7E4.27c, possible integral membrane protein, len: FT 94 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9K493" FT /protein_id="CAB94615.1" FT /translation="MISEGTEPRMPEDTEVSREPVVTPVRVVIGFCLVAPFVAMLWVGS FT YAKTDPAFIGIPFFYWYQMAWVLISTLLTVTAYKLWQRDQRGRREGGTK" FT CDS complement(10122..10886) FT /transl_table=11 FT /gene="SCO5231" FT /gene_synonym="SC7E4.28c" FT /product="putative gntR-family transcriptional regulator" FT /note="SC7E4.28c, probable gntR-family transcriptional FT regulator, len: 254 aa; similar to SW:HUTC_PSEPU FT (EMBL:M33922) Pseudomonas putida histidine utilization FT repressor HutC, 248 aa; fasta scores: opt: 355 z-score: FT 415.1 E(): 1.2e-15; 31.6% identity in 234 aa overlap. FT Contains Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family and match to Prosite entry FT PS00043 Bacterial regulatory proteins, gntR family FT signature. Contains also a possible helix-turn-helix motif FT at residues 45..66 (+3.08 SD)" FT /db_xref="GOA:Q9K492" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/Swiss-Prot:Q9K492" FT /protein_id="CAB94616.1" FT /translation="MSTDVSSAENEGGATVRTARVPKYYRLKKHLLDMTRTQTPGTPVP FT PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA FT QGLEPTSQLLDIGYITADDRLAGLLDITAGGRVLRIERLRMANGEPMAIETTHLSAKRF FT PALRRSLVKYTSLYTALAEVYDVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH FT SQDRTGQPVEWVRSVYRGDRYKFVARLKRPQD" FT misc_feature complement(10635..10772) FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 65.80, E-value FT 8.7e-19" FT misc_feature complement(10683..10757) FT /note="PS00043 Bacterial regulatory proteins, gntR family FT signature" FT RBS 11330..11335 FT CDS 11342..12619 FT /transl_table=11 FT /gene="SCO5232" FT /gene_synonym="SC7E4.29" FT /product="putative sugar transporter sugar binding protein" FT /note="SC7E4.29, possible sugar transporter sugar binding FT protein, len: 425 aa; similar to TR:Q9RK79 (EMBL:AL132662) FT Streptomyces coelicolor putative sugar transporter sugar FT binding protein SCF11.11, 422 aa; fasta scores: opt: 917 FT z-score: 991.5 E(): 0; 37.9% identity in 417 aa overlap and FT to SW:MALX_STRPN (EMBL:L08611) Streptococcus pneumoniae FT maltose/maltodextrin-binding protein precursor MalX, 423 FT aa; fasta scores: opt: 312 z-score: 340.7 E(): 1.7e-11; FT 22.9% identity in 428 aa overlap. Contains Pfam match to FT entry PF01547 SBP_bacterial_1, Bacterial extracellular FT solute-binding protein and correctly situated match to FT Prosite entry PS00013 Prokaryotic membrane lipoprotein FT lipid attachment site. Contains also possible N-terminal FT region signal peptide sequence" FT /db_xref="GOA:Q9K491" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:Q9K491" FT /protein_id="CAB94617.1" FT /translation="MKRKLIAAIGIAGMMVSIAACGGDSDDDGKKAGADGYAGETLTVW FT VMDGSSPDDWQADLAKDFEAKTKAKVKFEIQKWNGIQQKLTTALSEENPPDVFEIGNTQ FT TPAYAKTGGLADLSDLKGEIGTDWSESLNKSAVFDGKQYAAPWFVVNRVVVYNKKIWAD FT AGIKELPKTRDEFYNDLKTIGEKTDAEPIYLPGQNWYHFVGLVIGEGGELVKKDGDKYV FT SNLADPKVAAATETYKKFQALSKAPKDKDEATPQQGEIFAKGKTGSFIGMGWEGATAIA FT TNPAIEKDLGYFTIPGPTADKPEGVFLGGSNLAVAAGSKKQDLAKEFLKLALSDKYEGG FT LAKANGVIPNKEALQSNLKGNAAAEAAAPAAGTGDTTPLIPEWAAVENDPNPIKTYLTA FT VMKGKSPADAAKQVEGEFNKRLAQQQ" FT misc_feature 11372..11404 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature 11756..12388 FT /note="Pfam match to entry PF01547 SBP_bacterial_1, FT Bacterial extracellular solute-binding protein, score FT 77.40, E-value 1e-20" FT CDS 12708..13694 FT /transl_table=11 FT /gene="SCO5233" FT /gene_synonym="SC7E4.30" FT /product="putative sugar transporter integral membrane FT protein" FT /note="SC7E4.30, possible sugar transporter integral FT membrane protein, len: 328 aa; similar to TR:Q9RK78 FT (EMBL:AL132662) Streptomyces coelicolor putative sugar FT transporter integral membrane protein SCF11.12, 302 aa; FT fasta scores: opt: 907 z-score: 1004.1 E(): 0; 46.6% FT identity in 298 aa overlap. Contains Pfam match to entry FT PF00528 BPD_transp, Binding-protein-dependent transport FT systems inner membrane component and possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q9K490" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9K490" FT /protein_id="CAB94618.1" FT /translation="MTVQTERPPSGPSDVRKADGGGTGGTRARAASRAGALAPYLLLLP FT AAAATVLLLGWPLVKDGLLSFQNLNMAQLIQHVTEWTGFDNYKEVLTGEDFWRVTVRSI FT IFTAVNVVLTMVVGGLIGLLLARLGRVMRFVLMIGLVLAWAMPVVAATTVYQWLFAQRF FT GVVNWVLDKLGWHSMADFSWTGSQFSTFFVVTVLIVWMSVPFVAINLYAATTTIPDELY FT EAAALDGAGMWRSFTSVTLPFLRPFLYATTFLEVIWIFKAFVQVYTFNGGGPDRLTEIL FT PVYAYIEGVGNQHYGMGAAIAVLTILILLGLTAYYLRIVLKQEEDEL" FT misc_feature 13344..13571 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 47.70, E-value 2.5e-10" FT RBS 13678..13683 FT CDS 13691..14521 FT /transl_table=11 FT /gene="SCO5234" FT /gene_synonym="SC7E4.31" FT /product="putative sugar transporter integral membrane FT protein" FT /note="SC7E4.31, possible sugar transporter integral FT membrane protein, len: 276 aa; similar to TR:Q9RK77 FT (EMBL:AL132662;) Streptomyces coelicolor putative sugar FT transporter integral membrane protein SCF11.13, 285 aa; FT fasta scores: opt: 1027 z-score: 1227.9 E(): 0; 54.3% FT identity in 278 aa overlap and to TR:Q9R9Q5 (EMBL:AF175299) FT Rhizobium meliloti putative inner membrane permease ThuG, FT 276 aa; fasta scores: opt: 554 z-score: 666.6 E(): 1.2e-29; FT 33.8% identity in 266 aa overlap. Contains Pfam match to FT entry PF00528 BPD_transp, Binding-protein-dependent FT transport systems inner membrane component and match to FT Prosite entry PS00402 Binding-protein-dependent transport FT systems inner membrane comp sign. Contains also possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9K489" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9K489" FT /protein_id="CAB94619.1" FT /translation="MKRSLFGRVWPNVTAVVLFIGLVFPVYWMFATAFKPTGDIISENP FT VWFPTDITFEHFKTATEADHFWTYVSNSLIVTVCAVVFSLVIALAGSFALARMRFKGRR FT GFIVGFMLAQMAPWEVMVIAIYMIVRDASMLNSLVPLTLFYMMMILPFTILTLRGFVAA FT VPKELEESAMVDGCTRAQAFRRVILPLLAPGLMSTSMFGFITAWNELPLVLVVNKEAES FT QTLPLWLTSFQTVFGDNWGATMAASSLFAIPILILFVYLQRKAVSGLTAGAVKG" FT misc_feature 14168..14392 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 60.30, E-value 4.3e-14" FT misc_feature 14171..14257 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS 14530..16020 FT /transl_table=11 FT /gene="SCO5235" FT /gene_synonym="SC7E4.32" FT /product="putative sugar hydrolase" FT /note="SC7E4.32, possible sugar hydrolase, len: 496 aa; FT similar to SW:HEXA_ALTSO (EMBL:D17399) Alteromonas sp. FT beta-hexosaminidase A precursor (EC 3.2.1.52) Cht60, 598 FT aa; fasta scores: opt: 486 z-score: 525.0 E(): 9e-22; 34.4% FT identity in 363 aa overlap and to TR O69862 FT (EMBL:AL023702;) Streptomyces coelicolor putative hydrolase FT SC1C3.20c, 506 aa; fasta scores: opt: 1849 z-score: 1988.9 FT E(): 0; 60.6% identity in 498 aa overlap. Contains Pfam FT match to entry PF00933 Glyco_hydro_3, Glycosyl hydrolase FT family 3 N terminal domain" FT /db_xref="GOA:Q9K488" FT /db_xref="InterPro:IPR001764" FT /db_xref="UniProtKB/TrEMBL:Q9K488" FT /protein_id="CAB94620.1" FT /translation="MTTLARATDTLTRDALAVLQPGFAGTTAPDWLLRRIGEGLASVAL FT FGRNVTSPEQVAALTAQLRAEREDLLVAIDEEGGDVTRLEVRTGSSFPGNHALGAVDDV FT GLTRAVAAELGRRLAAAGVNFNWAPSADVNSNPDNPVIGVRAFGSDTDLVARHTAAYIT FT GMQSSGVATSAKHFPGHGDTGIDSHHAMPRIDVGADVLAERDLVPFRAAIAAGSRAVMS FT AHILVPALDPELPATLSRRILTDLLRGELGYDGLIVTDGIEMKAIAGTYGIERGTVMAI FT AAGADAICVGGGLHDEGTVRRLGDALVEAVRAGELPEERLADAAERVRSLSRWAAENRP FT ADGASDTADGDVGLRAARRALRVTVAGEPAPLTEAPYVAAFTPVANIAVGDETPWGVAA FT ELGRLLPGTETGSFHGADAGREALAAAGSRRIVAVVRDEHRHPWMAAALDVLLAARPDT FT VVVEMGVPRAEPRGAVHLATHGAARVCGRAAAEAIAGV" FT misc_feature 14599..15471 FT /note="Pfam match to entry PF00933 Glyco_hydro_3, Glycosyl FT hydrolase family 3 N terminal domain, score 194.60, E-value FT 1.5e-54" FT CDS complement(16341..17126) FT /transl_table=11 FT /gene="SCO5236" FT /gene_synonym="SC7E4.33c" FT /gene_synonym="nagB" FT /product="putative glucosamine phosphate isomerase" FT /note="SC7E4.33c, nagB, probable glucosamine phosphate FT isomerase, len: 261 aa; similar to SW:NAGB_ECOLI FT (EMBL:M19284) Escherichia coli glucosamine-6-phosphate FT isomerase (EC 5.3.1.10) NagB, 266 aa; fasta scores: opt: FT 630 z-score: 704.6 E(): 8.9e-32; 44.6% identity in 233 aa FT overlap. Contains Pfam match to entry PF01182 FT Glucosamine_iso, Glucosamine-6-phosphate isomerase" FT /db_xref="GOA:Q9K487" FT /db_xref="HSSP:1FS5" FT /db_xref="InterPro:IPR018322" FT /db_xref="UniProtKB/Swiss-Prot:Q9K487" FT /protein_id="CAB94621.1" FT /translation="MEVVIVPDAKAGGELIAEAMAQLLRRKPDALLGVATGSTPLPVYE FT ALAAKVRSGAVDTAQARIAQLDEYVGLPAEHPESYRSVLRREVLEPLGIDMDAFMGPDG FT TAADVQAACEAYDTALGGSGGVDLQLLGIGTDGHIGFNEPCSSLASRTRIKTLTEQTRI FT DNARFFDGDIEQVPHHVITQGIGTILEARHVVLLATGEGKADAVAASVEGPVAAVCPAS FT ALQLHPHATVVVDEAAASKLKLADYFRHTYAHKPDWQGI" FT misc_feature complement(16419..17069) FT /note="Pfam match to entry PF01182 Glucosamine_iso, FT Glucosamine-6-phosphate isomerase, score 273.60, E-value FT 2.5e-78" FT CDS complement(17261..18013) FT /transl_table=11 FT /gene="SCO5237" FT /gene_synonym="SC7E4.34c" FT /product="putative oxidoreductase" FT /note="SC7E4.34c, probable oxidoreductase, len: 250 aa; FT highly similar to TR:Q9RKS8 (EMBL:AL132824) Streptomyces FT coelicolor reductase SCAH10.29, 262 aa; fasta scores: opt: FT 807 z-score: 863.1 E(): 0; 52.4% identity in 252 aa overlap FT and to SW:VER1_ASPPA (EMBL:M91369) Aspergillus parasiticus FT versicolorin reductase (EC 1.1.-.-) Ver1, 262 aa; fasta FT scores: opt: 469 z-score: 506.7 E(): 9.4e-21; 39.2% FT identity in 255 aa overlap. Contains Pfam match to entry FT PF00106 adh_short, short chain dehydrogenase and PF00678 FT adh_short_C2, Short chain dehydrogenase/reductase FT C-terminus" FT /db_xref="GOA:Q9K486" FT /db_xref="HSSP:1G0N" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9K486" FT /protein_id="CAB94622.1" FT /translation="MGVLAGRTALVTGASRGIGRGIAERLGRDGARVAVHYGRNEAAAK FT ETVAAIEAGGGSAFTIRADLGAPGAAEALWEQFDRHADGLDVLVNNAGIGNTRPIGEIG FT EAEYDAVFTVNVKAPFFILKHGMGRLRDGGRVVNISSGLARTAVMPDNMAYAMTKGALD FT VFSRDLSKVLGTRGITVNSVAPGIIDTDNTAGMLHGSEGGWERAAAFSALGGVGTAAEV FT ADVVAFLASHGGRWVTGSWVDATGGSLT" FT misc_feature complement(17282..17374) FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 23.40, FT E-value 6.7e-05" FT misc_feature complement(17441..17995) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 183.60, E-value 3.2e-51" FT CDS 18108..18752 FT /transl_table=11 FT /gene="SCO5238" FT /gene_synonym="SC7E4.35" FT /product="putative TetR-family protein" FT /note="SC7E4.35, possible TetR-family protein, len: 214 aa; FT similar to TR:CAB69777 (EMBL:AL137187) Streptomyces FT coelicolor putative tetR-family transcriptional regulator FT SC7A8.28, 194 aa; fasta scores: opt: 326 z-score: 399.8 FT E(): 8.5e-15; 34.9% identity in 192 aa overlap and to FT TR:CAB93063 (EMBL:AL357432) Streptomyces coelicolor FT putative transcriptional regulator SCD95A.36c, 202 aa; FT fasta scores: opt: 458 z-score: 451.3 E(): 1.5e-19; 41.8% FT identity in 194 aa overlap. Contains Pfam match to entry FT PF00440 tetR, Bacterial regulatory proteins, tetR family" FT /db_xref="GOA:Q9K485" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9K485" FT /protein_id="CAB94623.1" FT /translation="MVSGEKSERSGAPARSGAARSRGRPRSFDRATALEAALLAFWEHG FT YEATSVSDLTRVMDIGAPSLYAAFGDKRSLFEEVVQEYGVRYGSFGERALAEEPTARAG FT IERMLREAAAEYTAPGRPHGCLVIHAAANCSTTEVEESLRERRNANIAAIESRIGADVD FT GGVLPPGTDAAALARYTGAMIQGMSQQARDGASRAELEALAEIALAVWPRG" FT misc_feature 18204..18344 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 45.40, E-value FT 4.2e-10" FT CDS 19181..20656 FT /transl_table=11 FT /gene="SCO5239" FT /gene_synonym="2SC7G11.01" FT /gene_synonym="SC7E4.36" FT /product="histidine kinase" FT /note="2SC7G11.01, possible histidine kinase, len: 491 aa; FT similar to TR:O05846 (EMBL:Z95120) Mycobacterium FT tuberculosis hypothetical 54.0 kDa protein MTCY07D11.06, FT 501 aa; fasta scores: opt: 1038 z-score: 1176.8 E(): 0; FT 48.9% identity in 380 aa overlap and to TR:O26226 FT (EMBL:AE000801) Methanobacterium thermoautotrophicum FT sensory transduction histidine kinase MTH123, 356 aa; fasta FT scores: opt: 372 z-score: 426.7 E(): 2.7e-16; 29.9% FT identity in 321 aa overlap. Contains Pfam match to entry FT PF00512 signal, Histidine kinase" FT /db_xref="GOA:Q8CJS0" FT /db_xref="InterPro:IPR013656" FT /db_xref="UniProtKB/TrEMBL:Q8CJS0" FT /protein_id="CAD55345.1" FT /translation="MPSMNELVRQHTALDDSDLEWLHLLVSEWQLLSDLSFADLVLWVP FT TRDGTRYVSVAQMRPNTGPTSYQDDMVGHLVPRGRRPMLDAALDEGRIVREGDPEWREE FT VPVRVESIPVRRQGRVLGVIARNTNLLTVRTPSRLELTYLQSASDLAQMIAAGAFPFEN FT QQVDMDASPRVGDGLIRVDGDGIVQYASPNALSAYHRMGLAADLVGHHLGRTTAELAPS FT RGPVDEALAKVASGWAPREFEIEAHDGVIQFRAIPLKPKGTRIGSLVLLRDVTELRRRE FT RELITKDATIREIHHRVKNNLQTVAALLRLQARRIESDRGREALEEAVRRVGSIAIVHE FT TLSQNLDERVEFDEIADRVLAMVAEISPGKVTGRRTGRFGILDAEVATPLSMVLTEVLQ FT NALEHGFRDGDTGTVEVSAVRGGTTKEARLLVTVQDDGVGLPEDFDPHRSGNLGLQIVR FT TLVEGELGGAFDMVQAAERGCRVILDIPVPAEK" FT misc_feature complement(19536..21778) FT /note="previously sequenced DNA fragment. EMBL:AJ239087 FT Streptomyces coelicolor wblE gene for hypothetical protein" FT misc_feature 20066..20638 FT /note="Pfam match to entry PF00512 signal, Histidine FT kinase, score -24.70, E-value 0.001" FT CDS complement(20905..21162) FT /transl_table=11 FT /gene="SCO5240" FT /gene_synonym="wblE" FT /gene_synonym="2SC7G11.02c" FT /product="hypothetical protein" FT /note="2SC7G11.02c, wblE, hypothetical protein, len: 85 aa; FT identical to previously sequenced TR:Q9X952 (EMBL:AJ239087) FT Streptomyces coelicolor hypothetical 9.7 kDa protein WblE, FT 85 aa" FT /db_xref="InterPro:IPR003482" FT /db_xref="UniProtKB/TrEMBL:Q9X952" FT /protein_id="CAC05979.1" FT /translation="MDWRHRAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVMEQ FT CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQASA" FT RBS complement(21168..21174) FT CDS complement(21483..22451) FT /transl_table=11 FT /gene="SCO5241" FT /gene_synonym="2SC7G11.03c" FT /product="conserved hypothetical protein" FT /note="2SC7G11.03c, hypothetical protein, len: 322 aa; FT similar to TR:O05848 (EMBL:Z95120) Mycobacterium FT tuberculosis hypothetical 34.5 kDa protein MTCY07D11.08c, FT 321 aa; fasta scores: opt: 694 z-score: 788.3 E(): 0; 39.9% FT identity in 328 aa overlap. Contains Pfam match to entry FT PF00781 DAGKc, Diacylglycerol kinase catalytic domain FT (presumed)" FT /db_xref="GOA:Q9F3M0" FT /db_xref="InterPro:IPR001206" FT /db_xref="UniProtKB/TrEMBL:Q9F3M0" FT /protein_id="CAC05978.1" FT /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEAVTTEYRGHARD FT LGRQAAQGDDIDLVVALGGDGTVNEVVNGLLHAGPDPDHLPGLAVVPGGSTNVFARALG FT LPNHAVEATGALLDALREGSERTVGLGLASGTPGSEDEAVPARWFTFNAGLGFDAGVVG FT RVEQHRERGRKSTHALYVRQVVRQLIGEPHRRSGTITLERAGEDPVTDLVLSIVSNTCP FT WTFLGNRPIYASPEASFDTALDVFGLSRLSTAAVARYGTQLLTSSPERGPRGRHAVSLH FT DLTEFTLHSKVPLPLQMDGDHLGLRTSVTFTGVRRALRVIV" FT misc_feature complement(22053..22448) FT /note="Pfam match to entry PF00781 DAGKc, Diacylglycerol FT kinase catalytic domain (presumed), score 47.80, E-value FT 2.3e-10" FT misc_feature complement(22461..25760) FT /note="previously sequenced DNA fragment. EMBL:AF162936 FT Streptomyces coelicolor A3(2) Na/H antiporter homolog gene, FT partial cds; and hypothetical protein (ushY), putative FT sigma factor SigH anti-sigma factor (ushX), and RNA FT polymerase alternative sigma factor (sigH) genes, complete FT cds." FT CDS 22579..23037 FT /transl_table=11 FT /gene="SCO5242" FT /gene_synonym="2SC7G11.04" FT /product="putative integral membrane protein" FT /note="2SC7G11.04, possible integral membrane protein, len: FT 152 aa; similar to TR:O05849 (EMBL:Z95120) Mycobacterium FT tuberculosis hypothetical 14.3 kDa protein MTCY07D11.09, FT 143 aa; fasta scores: opt: 177 z-score: 215.5 E(): 0.00015; FT 33.8% identity in 136 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9F3L9" FT /protein_id="CAC05977.1" FT /translation="MSSEQTPTPASATAEETTPRPGRLTAAAAIAALEGLALVVGGGWM FT LVEGLTGHPDDRTSAVTGGVTLIVLALLPLLAARGLIARRGWSRGPAVITQIMALPVAY FT NMVRADSLAVPAGIVLGVVAVTALVLLVNPTTTQALGIRGPGNAGKQP" FT CDS complement(23057..24142) FT /transl_table=11 FT /gene="SCO5243" FT /gene_synonym="sig1" FT /gene_synonym="2SC7G11.05c" FT /product="RNA polymerase sigma factor" FT /note="2SC7G11.05c, sig1, RNA polymerase sigma factor, len: FT 361 aa; identical to previously sequenced TR:Q9RIT0 FT (EMBL:AJ249450) Streptomyces coelicolor A3(2) Sig1 protein, FT 361 aa and similar TR:CAB93744 (EMBL:AL357613) Streptomyces FT coelicolor regulatory protein SC5F8.16c, 83 aa; fasta FT scores: opt: 414 z-score: 534.4 E(): 3.9e-24; 72.0% FT identity in 82 aa overlap. Contains Pfam match to entry FT PF00140 sigma70, Sigma-70 factor and possible FT helix-turn-helix motif at residues 326..347 (+7.10 SD)" FT /db_xref="GOA:Q7AKF9" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q7AKF9" FT /protein_id="CAC05976.1" FT /translation="MRDGDGPVRDEERGTRELPAEGTRSPNEARRTADGIDGIPEQARP FT HPEDETSPGAAVPGEGQRTGETPVRPVRAEARARERATGGTMSEHERHADGHAPGARGT FT QGTRHDPQDRSGARLLFAELRTLEKDSPEYAELRNRLVRMHLPLVEHLARRFRNRGEPL FT DDLTQVATIGLIKSVDRFDPDRGVEFSTYATPTVVGEIKRHFRDKGWAVRVPRRLQELR FT LALTTATAELSQLHGRSPTVHELAEKLSISEEEVLEGLESANAYSTLSLDVPDTDDESP FT AVADTLGAEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQEVGISQM FT HVSRLLARTLAQLREKLLVEE" FT misc_feature complement(23078..23740) FT /note="Pfam match to entry PF00140 sigma70, Sigma-70 FT factor, score 266.90, E-value 2.7e-76" FT CDS complement(24139..24552) FT /transl_table=11 FT /gene="SCO5244" FT /gene_synonym="prs" FT /gene_synonym="2SC7G11.06c" FT /product="anti-sigma factor" FT /note="2SC7G11.06c, prs1, anti-sigma factor, len: 137 aa; FT identical to previously sequenced TR:Q9R3X8 (EMBL:AJ249450) FT Streptomyces coelicolor A3(2) putative regulator of Sig1, FT Prs1 protein or UshX, 137 aa" FT /db_xref="GOA:Q7AKF8" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q7AKF8" FT /protein_id="CAC05975.1" FT /translation="MSQIAGEPATQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE FT IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGHAPSRDTFAWTV FT LSALAGKVSSAVDEDKTVSISLYKQRGAGPGPT" FT RBS complement(24555..24562) FT CDS complement(24803..25063) FT /transl_table=11 FT /gene="SCO5245" FT /gene_synonym="2SC7G11.07c" FT /product="conserved hypothetical protein" FT /note="2SC7G11.07c, hypothetical protein, len: 86 aa; FT identical to previously sequenced TR:Q9R3I9 (EMBL:AJ249450) FT Streptomyces coelicolor A3(2) hypothetical 9.6 kDa protein FT UshY, 86 aa. Contains Pfam match to entry PF02148 zf-UBP, FT Zn-finger in ubiquitin-hydrolases and other proteins" FT /db_xref="GOA:Q7AKF7" FT /db_xref="InterPro:IPR001607" FT /db_xref="UniProtKB/TrEMBL:Q7AKF7" FT /protein_id="CAC05974.1" FT /translation="MKQCTHADALPHPEPEPCGETCPECLAEGTDPVQLRLCLVCGHVG FT CCDSSPNRHATAHYKESGHPLMRTFEPGESWRWCFVDHVLV" FT misc_feature complement(24824..24991) FT /note="Pfam match to entry PF02148 zf-UBP, Zn-finger in FT ubiquitin-hydrolases and other proteins, score 28.50, FT E-value 1.4e-06" FT RBS 25118..25121 FT CDS 25125..26717 FT /transl_table=11 FT /gene="SCO5246" FT /gene_synonym="2SC7G11.08" FT /product="putative Na+/H+ antiporter" FT /note="2SC7G11.08, possible Na+/H+ antiporter, len: 530 aa; FT identical to C-terminal region of previously sequenced FT TR:Q9RPC9 (EMBL:AF162936) Streptomyces coelicolor A3(2) FT Na/H antiporter homolog (fragment), 212 aa and similar to FT SW:YJCE_ECOLI: (EMBL:U00006) Escherichia coli putative FT Na(+)/H(+) exchanger YjcE, 549 aa; fasta scores: opt: 516 FT z-score: 557.0 E(): 1.5e-23; 30.1% identity in 552 aa FT overlap. Contains Pfam match to entry PF00999 FT Na_H_Exchanger, Sodium/hydrogen exchanger family and FT possible hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9F3L8" FT /db_xref="InterPro:IPR018422" FT /db_xref="UniProtKB/TrEMBL:Q9F3L8" FT /protein_id="CAC05973.1" FT /translation="MDVMPLLLLVAGSAAVAAAGRRVPVPVPLLLVAAGLAVSYVPGVP FT DYTLDPHIVLPLLLPPLLYTAATDSSYLDLRAQARPVALLSVGYVLFATFVVGCAAYLI FT VPGLPLTAALVLGAVVAPPDAVAATAVARRVGLPSRITTILQGESLVNDATAITAFKVA FT LAAAVGEGATWAGGIGEFLIAAVGGVGVGLVLMVPLHWLRTHLTEALLQNTLSLLIPFV FT AYAVAEQVQASGVLAVVVVALYLGHRAWEVDFATRLQEEAVWKMVAFVLESAVFALIGL FT QLPVVLKGLGEYEGADAAWYALAVFLVVAVARFVWVYPATYLPRLSARVRAREGELSWK FT GPFVIGWAGMRGVVSLAIAFSIPLTVHGGEPFPERNLILFLTFTTVIGTLVVQGVSLPP FT LIRLLKFPAHDVQAETLAEANAQAQASRVAELRLDDLLADERNALPAPLADRLRMVLER FT RRNAVWERLGQVNPVTGETVDDTYRRLSREMISAEREVFVRLRDGRYIDDEMLRTLLRR FT LDLEEAAAYREAT" FT misc_feature 25134..26348 FT /note="Pfam match to entry PF00999 Na_H_Exchanger, FT Sodium/hydrogen exchanger family, score 230.10, E-value FT 3.2e-65" FT CDS complement(26766..27674) FT /transl_table=11 FT /gene="SCO5247" FT /gene_synonym="2SC7G11.09c" FT /product="putative deaminase" FT /note="2SC7G11.09c, possible deaminase, len: 302 aa; FT similar to SW:1A1D_PYRHO (EMBL:AP000001) Pyrococcus FT horikoshii putative 1-aminocyclopropane-1-carboxylate FT deaminase (EC 4.1.99.4) PHBE027, 325 aa; fasta scores: opt: FT 274 z-score: 309.9 E(): 8.6e-10; 29.7% identity in 283 aa FT overlap" FT /db_xref="GOA:Q9F3L7" FT /db_xref="UniProtKB/TrEMBL:Q9F3L7" FT /protein_id="CAC05972.1" FT /translation="MTGTDTRQLAALRPRLPSPLHEVADGRFERHGVRLLLKRDDLIHP FT ELVGNKWRKLAPNLATADGRTVVTFGGAYSNHLRAAAAAGRLLGLPTVGVVRGQELAGL FT PLNPSLARCAADGMRLHFVDRSTYRRKSEPETLAALLRAAGAEGAVVVPEGGSNADAVR FT GCRALGEELGTHADVAAVACGTGGTLAGLAAGLPRGRRALGIPVLKGGFLEGDIRRLQE FT RAFGGPRGDWSLEDRFHHGGYARTTPGLDAFAADFEHRHGLPVERVYVAKMLYALLTLT FT EEGAFPRGTTLAAVVTGRPFP" FT CDS complement(27788..28366) FT /transl_table=11 FT /gene="SCO5248" FT /gene_synonym="2SC7G11.10c" FT /product="hypothetical protein" FT /note="2SC7G11.10c, hypothetical protein, len: 192 aa; FT similar to TR:O06288 (EMBL:Z95557) Mycobacterium FT tuberculosis hypothetical 30.6 kDa protein MTCY07H7.28c, FT 275 aa; fasta scores: opt: 180 z-score: 221.9 E(): 6.8e-05; FT 31.8% identity in 176 aa overlap" FT /db_xref="GOA:Q9F3L6" FT /db_xref="InterPro:IPR002502" FT /db_xref="UniProtKB/TrEMBL:Q9F3L6" FT /protein_id="CAC05971.1" FT /translation="MSASSFLKALKAEGLTVVQVGDWRDHNRNHKGPWGPVHGVMIHHT FT VTKGSARTVDICRKGYEGLPGPLCHGVVTKDGKVHLVGYGRANHAGLGDDDVLRAVIAE FT KALPRDNEANTDGNRHFYGFECENLGDGDDPWPAAQLEAIERAAAAVCRHHGWNERSVI FT GHLEWQPGKVDPRGFTMTSMRNRIRDRLK" FT CDS 28674..30080 FT /transl_table=11 FT /gene="SCO5249" FT /gene_synonym="2SC7G11.11" FT /product="putative nucleotide-binding protein" FT /note="2SC7G11.11, possible nucleotide-binding protein, FT len: 468 aa; highly similar to TR:Q54255 (EMBL:L76204) FT Streptomyces griseus sporulation protein, 470 aa; fasta FT scores: opt: 2008 z-score: 2272.9 E(): 0; 64.1% identity in FT 462 aa overlap. Contains Pfam match to entry PF00027 FT cNMP_binding, Cyclic nucleotide-binding domain" FT /db_xref="InterPro:IPR014710" FT /db_xref="UniProtKB/TrEMBL:Q9F3L5" FT /protein_id="CAC05970.1" FT /translation="MSVGEEVRTEQTRPQQSLGTAAARNLATTTKSVPQMQEISSRWLL FT RSLPWVDIQGGTYRVNRRLTFAVGDGRVTFVKTGDRVEVVPAELGELPALRSYEDDEVL FT SELAQRCEQREFGPGEVIASFGARADEVYLLAHGKVEKIGTGPYGDDAVLGVLADGAYF FT GDQALLDGDAIWEYTARTVTACTVLVLPRQEVDQVAERADSLREHLEQRRSIPEQRTNR FT HGEKEIDLAAGHSGEPDIPHTFVDYEARPREYELSVAQTVLRIHSRVADLYNQPMNQTE FT QQIRLTVEALKERQEHELINNREFGLLHNCEYDQRIQPHDGVPGPDDLDELLSRRRGTK FT LLLAHPRAIAAIGRELNKRGLVPETIDVAGNRIPTWRGVPIYPCNKIPVTEARTSSIIA FT MRTGEQDQGVIGLRATGIPDEIEPSLSVRFMGINEQAVIKYLVTAYYSAAVLVPDALGV FT LENVEIGRWR" FT misc_feature 29001..29285 FT /note="Pfam match to entry PF00027 cNMP_binding, Cyclic FT nucleotide-binding domain, score 72.00, E-value 1.3e-17" FT misc_feature complement(30129..38720) FT /note="previously sequenced DNA fragment. EMBL:AF104994 FT Streptomyces coelicolor A3(2) periplasmic binding protein FT (atrA), permease (AtrB), ATP-binding protein (atrC), FT methyltransferase (metZ), signal peptidase, Ni-containing FT superoxide dismutase (sodN), puromycin N-acetyltransferase FT (pat), and geranyl transferase (gtr) genes, complete cds; FT and unknown genes." FT RBS 30156..30161 FT CDS 30166..31326 FT /transl_table=11 FT /gene="SCO5250" FT /gene_synonym="gtr" FT /gene_synonym="2SC7G11.12" FT /product="polyprenyl synthetase" FT /note="2SC7G11.12, gtr, polyprenyl synthetase, len: 386 aa; FT previously sequenced as TR:Q9RGW1 (EMBL:AF104994) FT Streptomyces coelicolor A3(2) geranyl transferase Gtr, 386 FT aa. Contains Pfam match to entry PF00348 polyprenyl_synt, FT Polyprenyl synthetases and match to Prosite entry PS00723 FT Polyprenyl synthetases signature 1" FT /db_xref="GOA:Q9F3L4" FT /db_xref="InterPro:IPR000092" FT /db_xref="UniProtKB/TrEMBL:Q9F3L4" FT /protein_id="CAC05969.1" FT /translation="MTETRRGATATCRPTGAPERHGPIGTQREKEPGEPSDGQGEAVVE FT GHEAALLLSESRASVDPELRSAIATLPESMRRVALYHFGWQHADGTPAAGNAGKAIRPA FT LVLTAAAALGGPGARAAAVRAAAAVELVHNFTLLHDDVMDRDATRRHRPTAWTVFGDAD FT AILAGDALQALALRLFAADPHPASAAAATRLADCVMELCEGQHADTAMERRPPDEVTLD FT ETLVMAEAKTGALLGCACAVGALYAGAATEDVEALDAFGREAGMAFQLIDDVIGIWGDP FT RHTGKPAGADLAARKKSLPVVAALTSGTPAAAELAELYTGPYDENKEDLERTALAVERA FT GGRDWAQAQAADRMARAMQELARAVPEPEAAGGLLALAEFVTRRST" FT misc_feature 30421..31206 FT /note="Pfam match to entry PF00348 polyprenyl_synt, FT Polyprenyl synthetases, score 157.60, E-value 2.1e-43" FT misc_feature 30574..30618 FT /note="PS00723 Polyprenyl synthetases signature 1" FT RBS 31646..31649 FT CDS 31658..32296 FT /transl_table=11 FT /gene="SCO5251" FT /gene_synonym="pat" FT /gene_synonym="2SC7G11.13" FT /product="acetyltransferase" FT /note="2SC7G11.13, pat, acetyltransferase, len: 212 aa; FT previously sequenced as TR:Q9RGW2 (EMBL:AF104994) FT Streptomyces coelicolor A3(2) puromycin N-acetyltransferase FT Pat, 210 aa. Contains Pfam match to entry PF00583 FT Acetyltransf, Acetyltransferase (GNAT) family" FT /db_xref="GOA:Q9F3L3" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9F3L3" FT /protein_id="CAC05968.1" FT /translation="MGVVIRTAGEDDRELVVRLLDEAFQDDPVSSWVFPGTEYRRRTHH FT RLMAAFADAVLADGRVDLTEDGAACALWLPVPAGEPAGDGPGAEQGSESGEGAEDGPAR FT IRAAVDPENERVELIARLTDGIHPSGRAHAYLWMIGVVPERQGEGLGTALIGTVLDRCD FT REGLPAYLEASSARGKALYERLGFEFTGRALDLPDGPRMWPMWREPRTP" FT misc_feature 31844..32221 FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 30.60, E-value FT 3.6e-05" FT RBS 32362..32365 FT CDS 32372..32956 FT /transl_table=11 FT /gene="SCO5252" FT /gene_synonym="2SC7G11.14" FT /product="conserved hypothetical protein" FT /note="2SC7G11.14, hypothetical protein, len: 194 aa; FT previously sequenced as TR:Q9RGW3 (EMBL:AF104994) FT Streptomyces coelicolor A3(2) hypothetical 18.8 kDa FT protein, 169 aa" FT /db_xref="GOA:Q9F3L2" FT /db_xref="InterPro:IPR002734" FT /db_xref="UniProtKB/TrEMBL:Q9F3L2" FT /protein_id="CAC05967.1" FT /translation="MRKLTYFVACSIDGFIGGPDGDASFMVPFVDEEFFEFLKSEYPET FT LPTHGRRPLGIDDLPNKRFDTIVQGRASYDLALKEGVTSPYAHLREYVASRTLTESPDP FT NVEIISTDLVGRVRELKAEDSAFGIYLCGGSAVAGELVDEVDELVVKTYPVVLGTGMPM FT FGSGFEVSAFVPDSVRTFGNGVVVRTYHRKR" FT CDS 32983..33204 FT /transl_table=11 FT /gene="SCO5253" FT /gene_synonym="2SC7G11.15" FT /product="hypothetical protein 2SC7G11.15" FT /note="2SC7G11.15, unknown, len: 73 aa" FT /db_xref="UniProtKB/TrEMBL:Q9F3L1" FT /protein_id="CAC05966.1" FT /translation="MDSDTYACPVCGQPVEAVVRRHKTLGIWVPEWAPGPCGNPKCEAG FT PGKNAGAAEAEARPGRPEHSRETVTENP" FT CDS complement(33312..33707) FT /transl_table=11 FT /gene="SCO5254" FT /gene_synonym="sodN" FT /gene_synonym="2SC7G11.16c" FT /product="superoxide dismutase" FT /note="2SC7G11.16c, sodN, superoxide dismutase, len: 131 FT aa; previously sequenced as TR:O51921 (EMBL:AF104994) FT Streptomyces coelicolor superoxide dismutase (EC 1.15.1.1) FT SodN, 131 aa" FT /db_xref="GOA:P80735" FT /db_xref="InterPro:IPR014123" FT /db_xref="PDB:1T6I" FT /db_xref="UniProtKB/Swiss-Prot:P80735" FT /protein_id="CAC05965.1" FT /translation="MLSRLFAPKVTVSAHCDLPCGVYDPAQARIEAESVKAVQEKMAGN FT DDPHFQTRATVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHQLVNDTLKALSAAKG FT SKDPATGQKALDYIAQIDKIFWETKKA" FT CDS 33850..34290 FT /transl_table=11 FT /gene="SCO5255" FT /gene_synonym="2SC7G11.17" FT /product="signal peptidase protein" FT /note="2SC7G11.17, signal peptidase protein, len: 146 aa; FT previously sequenced as TR:O51920 (EMBL:AF104994) FT Streptomyces coelicolor signal peptidase-like protein, 148 FT aa. Contains Pfam match to entry PF00461 Peptidase_S26, FT Signal peptidase I and match to Prosite entry PS00501 FT Signal peptidases I serine active site" FT /db_xref="HSSP:1KN9" FT /db_xref="InterPro:IPR019759" FT /db_xref="UniProtKB/TrEMBL:Q9F3L0" FT /protein_id="CAC05964.1" FT /translation="MMPEQLSQETERARGALPFGPAEVTGPSMVPTLHHGDVLLVHWGA FT RVRPGDVVVLRHPFQQDLLVVKRAAERRGAGWWVLGDNAFAGGDSTDYGVVPQDLVLGR FT VRFRYRPPRAGQRSPLAVVRWALSAVRPVPADRSASRRLRAR" FT misc_feature 33919..34023 FT /note="Pfam match to entry PF00461 Peptidase_S26, Signal FT peptidase I, score 14.90, E-value 0.0014" FT misc_feature 33925..33948 FT /note="PS00501 Signal peptidases I serine active site" FT CDS complement(34194..34823) FT /transl_table=11 FT /gene="SCO5256" FT /gene_synonym="2SC7G11.18c" FT /product="hypothetical protein" FT /note="2SC7G11.18c, hypothetical protein, len: 209 aa; FT similar to TR:CAB70944 (EMBL:AL137778) Streptomyces FT coelicolor hypothetical 20.3 kDa protein SCL2.32, 186 aa; FT fasta scores: opt: 314 z-score: 396.2 E(): 1.3e-14; 36.6% FT identity in 183 aa overlap" FT /db_xref="InterPro:IPR010852" FT /db_xref="UniProtKB/TrEMBL:Q9F3K9" FT /protein_id="CAC05963.1" FT /translation="MELAYYSDYAVRLVNTEEPSRGQDSLTSVEAVRELFGANQSAARR FT ASDADVTRFRSVRGRLRAVFEAADGGDETLAVDLLNSLLLEFPVSPQISGHDHRAEDGS FT PLWHMHLADHPSNATAGFAAIAAMGLAFHLTEYGVDRLGLCEAAPCRNAYLDTSTNRSR FT RYCSDRCATRANVAAYRARKRLEADRSAGTGLTADSAQRTTASGER" FT RBS 34911..34916 FT CDS 34922..35731 FT /transl_table=11 FT /gene="SCO5257" FT /gene_synonym="metZ" FT /gene_synonym="2SC7G11.19" FT /product="methyltransferase" FT /note="2SC7G11.19, metZ, methyltransferase, len: 269 aa; FT previously sequenced as TR:Q9RGW5 (EMBL:AF104994) FT Streptomyces coelicolor A3(2) methyltransferase MetZ, 268 FT aa" FT /db_xref="GOA:Q9F3K8" FT /db_xref="InterPro:IPR013217" FT /db_xref="UniProtKB/TrEMBL:Q9F3K8" FT /protein_id="CAC05962.1" FT /translation="MTNADTTTATTAGTTATTTATAGADWQAWQRSWDRQQEWYMPDRE FT ERFRIMLDMVEALVGPAPRVLDLACGTGTITARLLDRFPDATSTGVDLDPALLAIAEGT FT FAGDDRVSFVAADLKDPDWPAKLPYDAYDAVLTATALHWFHAEPLADLYGRVAELVRDG FT GVFMNADHMIDEATPRINAAERAQRHARMDAAKGQGALDWAEWWQLAAEDPVLAGPTAR FT RFEIYGEHADGEMPSAAWHARVLREKGFGEARPVWCSPSDTLLLAVK" FT stem_loop complement(35746..35799) FT /note="possible stem loop. Score 64: 24/26 (92%) matches, 0 FT gaps" FT CDS complement(35810..36571) FT /transl_table=11 FT /gene="SCO5258" FT /gene_synonym="atrC" FT /gene_synonym="2SC7G11.20c" FT /product="ATP-binding protein" FT /note="2SC7G11.20c, atrC, ATP-binding protein, len: 253 aa; FT previously sequenced as TR:Q9RGW6 (EMBL:AF104994) FT Streptomyces coelicolor A3(2) ATP-binding protein AtrC, 239 FT aa. Contains Pfam match to entry PF00005 ABC_tran, ABC FT transporter and matches to Prosite entries PS00017 FT ATP/GTP-binding site motif A (P-loop) and PS00211 ABC FT transporters family signature" FT /db_xref="GOA:Q9F3K7" FT /db_xref="HSSP:1B0U" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9F3K7" FT /protein_id="CAC05961.1" FT /translation="MTAMVKAEGVHKSFGAVEVLKGIDLEVKQGEVFCLIGPSGSGKST FT FLRCINHLEKINAGRLYVDGELVGYRQKGDKLYELKDSEVALKRRDIGMVFQRFNLFPH FT MTAVENVMEAPVQVKGMSRAQARERARGLLERVGLADKAGNYPSQLSGGQQQRVAIARA FT LAMDPKLMLFDEPTSALDPELVGDVLDVMRDLAESGMTMVVVTHEMGFAREVGDSLVFM FT DNGVVVESGNPRDVLTDPQHDRTKAFLSKVL" FT misc_feature complement(35897..36484) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 228.00, E-value 1.4e-64" FT misc_feature complement(36080..36124) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(36440..36463) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(36568..37518) FT /transl_table=11 FT /gene="SCO5259" FT /gene_synonym="atrB" FT /gene_synonym="2SC7G11.21c" FT /product="permease" FT /note="2SC7G11.21c, atrB, permease, len: 316 aa; previously FT sequenced as TR:Q9RGW7 (EMBL:AF104994) Streptomyces FT coelicolor A3(2) permease AtrB, 313 aa. Contains Pfam match FT to entry PF00528 BPD_transp, Binding-protein-dependent FT transport systems inner membrane component and match to FT Prosite entry PS00402 Binding-protein-dependent transport FT systems inner membrane comp sign. Also contains possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9F3K6" FT /db_xref="InterPro:IPR010065" FT /db_xref="UniProtKB/TrEMBL:Q9F3K6" FT /protein_id="CAC05960.1" FT /translation="MTVDIDKTAGGPAGTPPTPPEAIKAIPVRHYGRYVSAVVAIALLA FT AVVYAFSQGKINWGAIPDYFFDDRVLTGMGKTLLITVLAMLIGVVGGILLAVMRLSKNP FT VTSSIAWFYIWFFRGTPVLVQLVVWFNLGLVFEYINLGPFYRDEWSDFMTPFLTALLGL FT GLNEAAYMAEICRAGLLAVDEGQTEAAHALGMSHTKTLRRIVVPQAMRVIVPPTGNEVI FT NMLKTTSLVSVVQYAELFRVAQDIGQTSGAPAEMLFLAAAWYLLLTSVFSVGQYYLERY FT YARGSSRSLPPTPMQKIRANLFSLSNRSSTTGGAA" FT RBS complement(36576..36582) FT misc_feature complement(36775..36987) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 63.60, E-value 4.4e-15" FT misc_feature complement(36898..36984) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS complement(37549..38511) FT /transl_table=11 FT /gene="SCO5260" FT /gene_synonym="atrA" FT /gene_synonym="2SC7G11.22c" FT /product="secreted protein" FT /note="2SC7G11.22c, atrA, secreted protein, len: 321 aa; FT identical to previously sequenced TR:Q9RGW8 (EMBL:AF104994) FT Streptomyces coelicolor A3(2) periplasmic binding protein FT AtrA, 321 aa. Contains Pfam match to entry PF00497 FT SBP_bac_3, Bacterial extracellular solute-binding proteins, FT family 3 and correctly situated match to Prosite entry FT PS00013 Prokaryotic membrane lipoprotein lipid attachment FT site. Also contains possible N-terminal region signal FT peptide sequence" FT /db_xref="GOA:Q9F3K5" FT /db_xref="HSSP:1WDN" FT /db_xref="InterPro:IPR001638" FT /db_xref="UniProtKB/TrEMBL:Q9F3K5" FT /protein_id="CAC05959.1" FT /translation="MTARSTRRTTAAHSRLAAVGAIAVAGALLLTGCGDQTENGDSGGS FT DTQSAGGAPLADKLPQSIRDKGTIKVGSDIAYAPVEFKDDSGKTVGIDPDLADALGKQL FT GVKFEFENGTFDTLITGLRSKRYDIAMSAMTDTKDRQEGIDGDTGKKVGQGVDFVDYFT FT AGVSIYTKKGDDQGIKTWSDLCGKKLVVQRGTVSEDLAKAENEKCPAGKKISMQPFDND FT QQAQTRLRAGGADAGSSDFPVAAYAVKTSGGGKDFELVGEQVEAAPYGIAVAKDNTQLR FT DALKAALDAVIANGEYKKIMDKWGVSEGAITEATVNGGK" FT misc_feature complement(37597..38388) FT /note="Pfam match to entry PF00497 SBP_bac_3, Bacterial FT extracellular solute-binding proteins, family 3, score FT 154.50, E-value 1.8e-42" FT misc_feature complement(38413..38445) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS 39151..40380 FT /transl_table=11 FT /gene="SCO5261" FT /gene_synonym="2SC7G11.23" FT /product="putative malate oxidoreductase" FT /note="2SC7G11.23, probable malate oxidoreductase, len: 409 FT aa; similar to SW:MAOX_BACST (EMBL:M19485) Bacillus FT stearothermophilus NAD-dependent malic enzyme (EC FT 1.1.1.38), 478 aa; fasta scores: opt: 1385 z-score: 1470.9 FT E(): 0; 55.0% identity in 391 aa overlap. Contains 2x Pfam FT matches to entry PF00390 malic, Malic enzyme" FT /db_xref="GOA:Q9F3K4" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9F3K4" FT /protein_id="CAC05958.1" FT /translation="MAAEIVNPRSDSEAGAEQEAGAEPLDSFDPAFALHRGGKMAVQAT FT VPIRDKEDLSLAYTPGVAKVCSAIAEQPDLVHDYTWKSSVVAVVTDGTAVLGLGDIGPE FT ASLPVMEGKAILFKQFGGVDAVPIALNCTDADEIVETVVRLAPSFGGVNLEDISAPRCF FT EIERKLQERLDIPVFHDDQHGTAVVTLAALRNAARLSGRTLGELRAVISGAGAAGVAIA FT KMLVEAGIGDVAVADRKGVVSADREDLTPVKQELASFTNKAGLSGPLEAALAGADVFIG FT VSGGTVPEPAVASMAEGAFVFAMANPNPEVHPEVAHKYAAVVATGRSDFPNQINNVLAF FT PGIFAGALQVRASRITEGMKLAAAEALASVVGDDLAADYVIPSPFDERVAPAVTAAVAA FT AARAEGVARR" FT misc_feature 39664..39834 FT /note="Pfam match to entry PF00390 malic, Malic enzyme, FT score 22.00, E-value 0.00016" FT misc_feature 40126..40272 FT /note="Pfam match to entry PF00390 malic, Malic enzyme, FT score 28.70, E-value 3.3e-06" FT CDS 40745..41710 FT /transl_table=11 FT /gene="SCO5262" FT /gene_synonym="2SC7G11.24" FT /product="putative dehydrogenase" FT /note="2SC7G11.24, possible dehydrogenase, len: 321 aa; FT similar to SW:ADH3_BACST (EMBL:Z27089) Bacillus FT stearothermophilus alcohol dehydrogenase (EC 1.1.1.1), 339 FT aa; fasta scores: opt: 303 z-score: 344.3 E(): 1e-11; 28.0% FT identity in 328 aa overlap. Contains Pfam match to entry FT PF00107 adh_zinc, Zinc-binding dehydrogenases" FT /db_xref="GOA:Q9F3K3" FT /db_xref="HSSP:1IYZ" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9F3K3" FT /protein_id="CAC05957.1" FT /translation="MFAVYAARIDRDQPLAGLELGELPAPEARPGWSVVDVRAASLNHH FT DLWSLRGVGLPEDRLPMILGCDAAGIDADGNEVVLHSVIGQTGHGVGPKEPRSILTERY FT PGTFAEQVAVPTWNILPKPKELSFEEAACLPTAWLTAYRMLFTNAGVRPGDSVLVQGAG FT GGVATAAIVLGKAAGLRVFATSRDEAKRKRALELGAVEAVETGARLPQRVDAVIETVGA FT ATWSHSIKSLRPGGTLVISGATSGDRPSHAELTRIFFLELKVVGSTMGSKDELEDLLSF FT CAATGVRPVIDEVLPMDRARDGFERMASGGQFGKIVLSNS" FT misc_feature 40793..41704 FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score 189.00, E-value 7.5e-53" FT RBS 42038..42042 FT CDS 42048..42614 FT /transl_table=11 FT /gene="SCO5263" FT /gene_synonym="2SC7G11.25" FT /product="hypothetical protein SC7G11.25" FT /note="2SC7G11.25, unknown, len: 188 aa" FT /db_xref="GOA:Q9F3K2" FT /db_xref="InterPro:IPR004176" FT /db_xref="UniProtKB/TrEMBL:Q9F3K2" FT /protein_id="CAC05956.1" FT /translation="MFERFTKDARAVVQGAVGHAEEARAETVEPEHLLLALLDREGSRA FT SFALAALGVGEHRDAVRRELGDARRRAGLSQSETEALAGLGIDVTEIVARVEEAHGVGA FT MSADDRKRGRRWSGHRSFSRGAKEVLEKALRVAVARRDRHIGDEHLLLALALRPGVPAE FT VLADHGVTHASLSRVLDEGAGKSCA" FT CDS complement(42683..43765) FT /transl_table=11 FT /gene="SCO5264" FT /gene_synonym="2SC7G11.26c" FT /product="hypothetical protein SC7G11.26c" FT /note="2SC7G11.26c, unknown, len: 360 aa. Contains possible FT coiled-coil region at approx. residues 157..212. High FT content in alanine, glutamic acid and arginine amino acid FT residues. Also highly hydrophilic" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9F3K1" FT /protein_id="CAC05955.1" FT /translation="MPPVFAHGRLRLYLLKLLDEAPRHGYEVIRLLEERFQGLYAPSAG FT TVYPRLAKLEAEGLVTHTTEGGRKVYAITDAGRAELADRSGELADLELEIRESVAELAA FT EIRADVRGAAGDLRREMRAAATAARRGASGAHDEGDGSTSTAGEGDEKEAWRAAKEEMR FT RVKQEWKEQARRAKDESRRARDEAQRARRQAKEAQERARAQAQEEVQRIAQRVQEQVQD FT HFSRGDWPTGLREGLSELAKEVGDFGKDFGKEFGKDWGFGRTDTGSPASRAERSPDPEY FT SVTPEDFPAGYAPSWAHEDAAESTGDPARDLDRLLDRFRDDIRDAARDHGVTSDQLRDT FT RHRLSEAAAHIGAILRTPKA" FT CDS complement(43767..44768) FT /transl_table=11 FT /gene="SCO5265" FT /gene_synonym="2SC7G11.27c" FT /product="hypothetical protein" FT /note="2SC7G11.27c, hypothetical protein, len: 333 aa; low FT similarity to TR:O32200 (EMBL:Z99120) Bacillus subtilis FT YvqG protein, 240 aa; fasta scores: opt: 172 z-score: 193.3 FT E(): 0.0027; 25.0% identity in 244 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9F3K0" FT /protein_id="CAC05954.1" FT /translation="MNFEGRDMARSVEEVCTMSEWSVAEPRKLTFDESVTRLHVRIVSG FT TVNVVGTDEGSARLEVSEIDGPPLIVTHRDGVLTVAYEDLPWKGFLKWLDRKGWRRSAV FT VSLAVPTGTRVEVGAVSAAAVVSGLDGPAEVKGVSGDTTLVSLAGPVRADTVSGNVEAQ FT ALTGDLRFNSVSGDLTVVEAGSSVRADSVSGSMIVDLDPTGGPTDISLNSVSGEIAIRL FT PQPADAQVEANTASGMVSSAFEDLRVGGQWGAKRITGRLGAGNGRLKATTVSGSIALLR FT RPATEDTPWEREPEESGPTGTARHGSGDNSASVRDQGATDAPSDGTTDKKVL" FT CDS 44854..45687 FT /transl_table=11 FT /gene="SCO5266" FT /gene_synonym="2SC7G11.28" FT /product="putative membrane protei" FT /note="2SC7G11.28, putative membrane protei, len: 277 aa; FT similar to N-terminal region of TR:CAB76994 (EMBL:AL159178) FT Streptomyces coelicolor putative integral membrane protein FT SCH22.25, 456 aa; fasta scores: opt: 141 z-score: 157.1 FT E(): 0.28; 29.3% identity in 263 aa overlap. Contains FT matches to Prosite entries PS00017 ATP/GTP-binding site FT motif A (P-loop) and PS00211 ABC transporters family FT signature. Contains possible hydrophobic membrane spanning FT region" FT /db_xref="UniProtKB/TrEMBL:Q9F3J9" FT /protein_id="CAC05953.1" FT /translation="MSTEESVSAPTPGALLLCRAEPDSVAAVAPLLGERMPLVRAGAQW FT SALVPEGGPWRDGREPVDRVVAGWAAALAVGAPWPVLALWWDADRAGYVLASGFRRPVG FT YVWLADGTPAGEDEAMRTFAARLGLDPVLDVQSLDRLTRADPDAEREFGAGAGARARLR FT GLLAVLARGGISLPAGLDPGEGAARLGAAARALPGVRRTESAGLRPTVDESPLAAWMPW FT TGGPGARVLALTQVATGLPLTVWGLRRRSGGWAAAGALLVGHGALGAAYGLSRHT" FT misc_feature 44956..44979 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 45295..45339 FT /note="PS00211 ABC transporters family signature" FT CDS complement(45940..46125) FT /transl_table=11 FT /gene="SCO5267" FT /gene_synonym="2SC7G11.29c" FT /product="hypothetical protein 2SC7G11.29c" FT /note="2SC7G11.29c, unknown, len: 61 aa. High content in FT glutamic acid amino acid residues" FT /db_xref="UniProtKB/TrEMBL:Q9F3J8" FT /protein_id="CAC05952.1" FT /translation="MYFTDRGIEELEKRRGEEEITFEWLAEQLRTFVDLNPDFEVPVER FT LATWLARLDDDEDEDE" FT RBS complement(46134..46137) FT CDS 46305..46775 FT /transl_table=11 FT /gene="SCO5268" FT /gene_synonym="2SC7G11.30" FT /product="hypothetical protein 2SC7G11.30" FT /note="2SC7G11.30, unknown, len: 156 aa" FT /db_xref="UniProtKB/TrEMBL:Q9F3J7" FT /protein_id="CAC05951.1" FT /translation="MGQEATRVTRIVLPDGTPVWARISGAAELPAPSGQLSYSDTGFTE FT RIEASVESLNALVTGVARSLAEPLRSVRPDEVSVQFGIELTAKAGKVVGLLADGEAKAG FT ISVTLTWHGGPPDPSAPDTRAPGGEPPDPTADASARAPGHGGSGAAASGSGA" FT RBS 46762..46765 FT CDS 46772..49009 FT /transl_table=11 FT /gene="SCO5269" FT /gene_synonym="2SC7G11.31" FT /product="hypothetical protein 2SC7G11.31" FT /note="2SC7G11.31, unknown, len: 745 aa. Contains 2 FT conserved repeat regions: 2x GENPEY and 4x GHGAYP" FT /db_xref="GOA:Q9F3J6" FT /db_xref="UniProtKB/TrEMBL:Q9F3J6" FT /protein_id="CAC05950.1" FT /translation="MTHGRAPGAPGARDAARRALRGLVMAATVRIHRPDAGYALDEPGT FT FLGSGYFIAPSWVLTCAHVACGGEGGEVVVVYEPAPGRGMSAVSGQVAAALPEGAGRLP FT GNWPAPDLALVRLSEPVDHECVYLSERPAAYFGEGTVLYAGWTVVDGRLRMLDGTLTVQ FT GTIGGWNADVQMRLGDNDLPDGVSGGPVIDPERGEVIGVLKSRSDHARGGTSTGLEQLR FT TLPVPAGELKSEPDDLYQAVVHAHDRYHRDRQRHPDARRHTWADVQGQLGARPGQTLSP FT DERVQLLGRLADLPPPASTRSLLDLLDSLQDFEAPAPLPAPRGWRDGLGALYEYARDDG FT ALYLVLDYAVHAMTADRPFLAPSTPAAEEALWAGVWQAAQRLGPGRRSALVERRMARMT FT ARRPAPGPAAGPRGAPAGGPEGAAAGQSSVLVEIVRRGWEPDRCDWSVFVVRSDGEATR FT LKEVQRVPLADLSAHLSAPLKEAFRQCDTPGRPAVLQVATEASLLALDVDEWRLGPEDE FT RLGTQRPVVLRCSDRDQLTENGENPEYGENPEYGETSGHGAYPGHGAYPGHGAYPGHGA FT YPAHRAYGENGDHRLDIDEERRARWRWLHAHPVTAAVLDCDDGLRKPVPPVEELRGLSH FT GTVPVLCRFDAHGVQGDAEGLARLVRGGFGVALWRRGYGLPETVCGEFHRGTLDQIAGP FT AGAHRLPEAVRDLRHRLRSGRPETFWAHGIALLYDDPHQPLPGAGDLLEAP" FT repeat_region 48386..48421 FT /note="2x conserved repeat translated in 2SC7G11.09c" FT repeat_region 48434..48505 FT RBS 49167..49170 FT CDS 49179..50201 FT /transl_table=11 FT /gene="SCO5270" FT /gene_synonym="2SC7G11.32" FT /product="conserved hypothetical protein" FT /note="2SC7G11.32, conserved hypothetical protein, len: 340 FT aa; similar to TR:CAB86114 (EMBL:AL163003) Streptomyces FT coelicolor hypothetical 37.1 kDa protein SCC24.20, 340 aa; FT fasta scores: opt: 1113 z-score: 1224.6 E(): 0; 54.5% FT identity in 343 aa overlap. Contains match to Prosite entry FT PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9F3J5" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9F3J5" FT /protein_id="CAC05949.1" FT /translation="MSESSEWLIYRGAGEPHDGVDRLPDPPPWRDFTSRDAAGSGDGSE FT DRRLGAHRHLAELHRPGAEELEMINAALYLRRPLLVTGSPGAGKSTLAHSVAYELGLGN FT VLRWSIVSRSELQDGLYHYDAIARLQDVQIAAQADNGPGSGTPGAVDGIGGYIRLGPLG FT TALLPSDKPRVLLIDELDKSDIDLPNDLLNVLEEGEFAIPELERVADRLPDRTAEVLTA FT DGVKVPVRDGRVRCRAFPFVVLTSNGERDFPAPLMRRCIHLELGRPDHNRLATFVRAHL FT GDEAARAGDDLVTRFLERSRSELLATDQLLNAIYLTDAAATPSRDRLADLLIQRLDRPR FT " FT misc_feature 49425..49448 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 50195..50201 FT repeat_region 50251..50331 FT /note="9x degenerate repeat:(T/C)CCGG(T/C)(G/A)(G/C)C" FT CDS 50359..53649 FT /transl_table=11 FT /gene="SCO5271" FT /gene_synonym="2SC7G11.33c" FT /product="conserved hypothetical protein" FT /note="2SC7G11.33, hypothetical protein, len: 1096 aa; FT similar to TR:CAB86115 (EMBL:AL163003) Streptomyces FT coelicolor hypothetical 145.7 kDa protein SCC24.21, 1349 FT aa; fasta scores: opt: 758 z-score: 652.1 E(): 7.4e-29; FT 29.8% identity in 1157 aa overlap. Contains a possible FT coiled-coil region at approx. residues 1011..1029" FT /db_xref="InterPro:IPR008912" FT /db_xref="UniProtKB/TrEMBL:Q9F3J4" FT /protein_id="CAC05948.1" FT /translation="MPADDPLARLVLRLRESGLDPDAEQLCDALWLARWTRSADATDAE FT PAPDARVAPAVVRPPTGPVSLPSDRARPPAPEPPAAPAARRVALYPLPPGDGPGAHGAG FT PARALPVGVPAAPVLPAPLELQRALRPLQGYRSPATPLRSELDEVATAEVSARAGGLIL FT PVRRYLSRRDARLQLVLDSSSSMRVWGRLFAELAQVFSRLGAFSDVQVSHLHQGPDGGP FT AVSRSADPYGAPLHAADRLSDPTGRRIVVLVSDCAGPLWHGGHAHRLLHHLTRQGPVVV FT LQPLPQRMWNRTRLPVTFGGLSRGDTLGGGAVLRVRTASGAAEARRGALAVPVLPPEPV FT ALGSWARLLAGAGPVPGAVGWVRADHPAAAATRPDRRRTPLERVSRFSAGASPAAARLA FT VYLAATPLCLPVMQLVQRTMLPGSGPSELAEVLVGGLVTRARADQGGDGSQWYDIDPEV FT REALLSRLGRDEAMLVLKHCSEYIEQHFGKGGPNFPALALAQLGDGGPGRPHPHPSGGE FT PGYPGENGGDAGTAPVPQPFAEVAARILERFMPLPEQFATYDSRTGPQVTAERPTHRAV FT VRARALLARFDGEGMVQDVIDAVQLLRGATEQERPAGADPELWGEYARCTLRLWEVQGG FT TALLREATRAAERAAASPHALRERAVLARVLHAAATDARRRGDRSGALDLLRRADREYA FT VACAAPGLDEAEALRLTLERVASLEAQWRLGGDSALLQSAVGMLEAFADAWPDRGDRPS FT QLLLAHGRTLLRLSEVTADPVQVRLYAEQSARSLRRGLEAGPAPETNESVRDRVRVLID FT LVDALLSAGGPLDEAQARTDEALGRVREQGQRAALLVRAGRVAVARYAESGEPPELHGA FT ADRFAQAAHWMSRDAPAHADVLAEWGGVLLRLATLEPADRRQGQLSRAIRVLRDCRMET FT PAGSRRVAHRLLLLGQALMVRYQARGDRVDLREAEHLFGLAAADAEDPLLAARCRLELG FT QAQFEAFQSLGRAARLDVAVEAFRAAAESARRAEEEAETERRRQEAVELAAQAHHWRGM FT SFEAAVRPRAAREAYAAARAQWDRLPDDRLATGEPTARQTAQRLADLE" FT RBS 53658..53661 FT CDS 53670..53864 FT /transl_table=11 FT /gene="SCO5272" FT /gene_synonym="2SC7G11.34" FT /product="hypothetical protein 2SC7G11.34" FT /note="2SC7G11.34, unknown, len: 64 aa" FT /db_xref="UniProtKB/TrEMBL:Q9F3J3" FT /protein_id="CAC05947.1" FT /translation="MDIRDEAGAEQATAGAGEPLPDLLELDLAQLGTVEHPVLREVLGE FT LRARAAEPSEMLWGFDNSF" FT CDS 53932..55794 FT /transl_table=11 FT /gene="SCO5273" FT /gene_synonym="2SC7G11.35" FT /product="hypothetical protein" FT /note="2SC7G11.35, hypothetical protein, len: 620 aa; FT N-terminal region similar to SW:ASLB_ECOLI (EMBL:M87049) FT Escherichia coli putative arylsulfatase regulatory protein FT AslB, 411 aa; blastp (consecutive) scores: Score= 166 (58.4 FT bits), Expec = 2.6e-19, Sum P(2)= 2.6e-19, Identities= FT 57/184 (30%), Positives= 82/184 (44%) and Score= 141 (49.6 FT bits), Expect= 2.6e-19, Sum P(2 = 2.6e-19, Identities= FT 47/165 (28%), Positives= 73/165 (44%). Contains Pfam match FT to entry PF01444 MoaA_NifB_PqqE, moaA / nifB / pqqE family" FT /db_xref="GOA:Q9F3J2" FT /db_xref="InterPro:IPR007197" FT /db_xref="UniProtKB/TrEMBL:Q9F3J2" FT /protein_id="CAC05946.1" FT /translation="MGTRRAGNAASCGTVPWRRLAATPADRHGMGGAGVSEQAMTDPAP FT GTPGRRTGPEGPIPFRQFIVKMHGRCNLACTYCYLYEGPDGSWRDRPAAASAAVLDRTA FT TRIAEHAERHALRDLALVLHGGEPLLAGAGPLAEVTGRVRELVPRGCQVHATVQTNATL FT LTEERLAVLADAGIRVGISLDGGTAAHNRRRVDHAGRPSWPAAARGARLVAERFPESYA FT GLLTVVDPTLDPVETYESLLGLRPPALDLLLPHGNWTAPPPGRTGVRYGDWLCAVFDRW FT WAAGRREVRVRLFEECVALLLGLPAATEALGLAPFDAVVVETDGSIEQVDSLKSAYPGA FT ARTGLDVFRHTFDDALRHPGVAARQAGTASLAGECRACPLLRVCGGGHYAHRYRAGHGF FT RNPSVYCADLQRFIRHVSSRLTAAAGGPTPGGPAASGLPGGGSAANGFPEDGSAAKGPS FT ATGPSATAPASVGLSVVGPASAGPYAVGPVPVGPSAIGPAPAGTSAAGPASTGTSAAGP FT ASAGPAVGPAPAGPAAAGPSVSAPASAGVSVVGPASADSSTVGPAPAGPTVAAPAATAP FT APAGPASAGSGASAGPASAGAASVRPVVSGSAAAGTGPAEGGAS" FT misc_feature 54262..54912 FT /note="Pfam match to entry PF01444 MoaA_NifB_PqqE, moaA / FT nifB / pqqE family, score -15.40, E-value 0.0013" FT misc_feature 55180..55791 FT /note="alanine, proline, serine and glycine amino acids FT rich region. Also high G+C content (80.22%)" FT CDS 55794..57419 FT /transl_table=11 FT /gene="SCO5274" FT /gene_synonym="2SC7G11.36" FT /product="hypothetical protein 2SC7G11.36" FT /note="2SC7G11.36, unknown, len: 541 aa. High content in FT alanine amino acid residues and in G+C (77.57%). Also FT contains 3x degenerate repeat: DA(P/T)GA(W/R)(G/S)(T/S)(4)" FT /db_xref="UniProtKB/TrEMBL:Q9F3J1" FT /protein_id="CAC05945.1" FT /translation="MFPVVPERALLELARTEGGSDTLTLLVRDQDTRRLLLLRAVLDAA FT EGAERSVCTAAQKARLRADWALLTEADRPPSPGAPTSEHRPGRAATRRDRDAPPGARGT FT SAVADAPTGAWSTHAADDAPTGAWGSRAGAGAAPAGGDARFANPARARLFHPLTGPWAR FT SCLRGLDAAPGPAGGERERRLRRDLAHFSAIAAVVAAGAGIPFSTRLTARAGVLALPSL FT GALHTARSGDVPVDVTCTEGRLVLRQADAPDVTVHLESGVGAWSGALAWTPAHALPGLT FT PTAPPLPLDDLDPYRELPDGPGHGDLRTPLALDDAERKRWLQAWSGTALALRTGGAQRL FT AEAGALLRCLVPLETPPDVGTGRGSCSATRREAFGALLSSTPPDPVTLAATLVHELQHA FT KLAALSDLVTLHRAGPAARYFAPWRADPRPYDGLLQGTYSHLALAAFHQRRALVDGLPD FT RDWAWAQHARYRAQVGAALPALVGSPDLTVRGRRFVDEMAATHERMAEHPAPRGHVARA FT QAYVASARTLWTRRHASTLPPSNG" FT repeat_region 56079..56184 FT /note="3x degenerate repeat unit translated in 2SC7G11.04c" FT RBS 57536..57540 FT CDS 57548..60571 FT /transl_table=11 FT /gene="SCO5275" FT /gene_synonym="2SC7G11.37" FT /product="putative ATP/GTP binding protein" FT /note="2SC7G11.37, possible ATP/GTP binding protein, len: FT 1007 aa; similar to (EMBL:AL391588) Streptomyces FT coelicolor SCCB12.04, 1148 aa; fasta scores: opt: 4019 FT z-score: 3915.8 E(): 0; 62.6% identity in 994 aa overlap. FT Contains match to Prosite entry PS00017 ATP/GTP-binding FT site motif A (P-loop)" FT /db_xref="GOA:Q9F3J0" FT /db_xref="InterPro:IPR002182" FT /db_xref="UniProtKB/TrEMBL:Q9F3J0" FT /protein_id="CAC05944.1" FT /translation="MSGARKPVETAERGTARQTVTIHFAGFNRAWAAWIGDRLERRGVR FT VVPLRWDSPADVPLVDLLRDLTLAEGRVLIIVSEWYFQLGPRTHEEWNAALREIVAPDP FT SRFAAVSVTTAAVPAAAAVLAPVALTNMGAEEAERRLLDRLDLPSEALAETSAESRRAP FT RFPAAMPDVWGVVPRRNTRFTGREPLFNEAYHLLQSSEPGAGVLTLHGMSGVGKTQFAA FT EYAHRFGSEYDVVWWVNAEKRVTYRRQLAELAPKLNLRTGQEYGERLRAVRDALRRGEP FT YSRWLLVLDGADEPDQIWDLLPTGPGHVIVTSRNPEWSEHNSKLLEVRVYPRDESVAFI FT RRRAPRLSEADADQLAEALGDLPLLLDQTAGWLNDSDLSVDEYIALLEGGIDSDVVKVS FT ADFPLAFQTAWSILLNKLRETVPESVDLLRLCTFFAPGFIPVRLLKEMPVDELPEQLAG FT LLNDPLLWNKAINQLRTYSVVRLESHEASLDEPVSAGESLYLHRMVHQIVHKDMPDADR FT SEFIDVVRRALAAADPGRPTETRLWPGYAEIVPHLKYADVLKSKDTKVQRMVLNCLRYM FT YFSGEYRAGIKLGERALTAWRRLLGPTHARIWELTYHYTNLLRAMGDYARTEALSRDAV FT EHLREERGPQDLDHLRAAAGLGGDLRGLARYDEALELSQWVLAAYRELLGDQDSRTLNA FT QNNLGVSLRLLGRYEETLETDRSTMEARRQLLRARHPWALSSEITYAIDLRLLGRYADA FT ESLQAKNVRENRIVMGPDNPQTLKAEYNLALCRYRLGERAPRGEEPGTMLSSVLERGER FT VLGETHPLTLIFATGQSCYAREHGDIDQARELSEAVVARYEMMLPAGHPFIAGARANQA FT LILRNVGEREHGHVLVEQALAEMTQAVGESHPWTVGCALNASALRNLVGDTEGAAELSR FT DTAARAIESLGRTHPLTLSTRIAYAADLRGLRDRRQAEKVEQEALSDLDATLGSKHTHT FT VSARSRNRPYWDFEPQTT" FT misc_feature 58178..58201 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 60693..60696 FT CDS 60703..61128 FT /transl_table=11 FT /gene="SCO5276" FT /gene_synonym="2SC7G11.38" FT /product="conserved hypothetical protein" FT /note="2SC7G11.38, conserved hypothetical protein, len: 141 FT aa; similar to TR:CAB86112 (EMBL:AL163003) Streptomyces FT coelicolor hypothetical 16.0 kDa protein SCC24.18, 153 aa; FT fasta scores: opt: 178 z-score: 212.6 E(): 0.00023; 32.4% FT identity in 145 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9F3I9" FT /protein_id="CAC05943.1" FT /translation="MILLGPVPEGADGPIPVEVDAHLDPSTADGLDLVFGDEETRDGAG FT QRVVRVARDVYTDGLDLARRCAAQAVRRFGELQEGLRPDEIEMQLAIKIDAGVATLVKS FT GAEAQLQITLRWQTAPASSPAAAPDGQGTGAADGAGS" FT misc_feature 60709..60711 FT /gene="none" FT /note="TTA leucine codon. Possible target for bldA FT regulation" FT CDS 61137..62066 FT /transl_table=11 FT /gene="SCO5277" FT /gene_synonym="SCCB12.01" FT /gene_synonym="2SC7G11.39" FT /product="putative magnesium chelatase" FT /note="SCCB12.01, possible ion chelatase subunit FT (fragment), len: >98 aa; similar to SW:BCHI_RHOCA FT (EMBL:Z11165) Rhodobacter capsulatus magnesium-chelatase 38 FT Kda subunit (MG-protoporphyrin IX chelatase) BchI, 350 aa; FT fasta scores: opt: 163 z-score: 216.2 E(): 0.00014; 38.1% FT identity in 97 aa overlap" FT /note="2SC7G11.39, possible magnesium chelatase (fragment), FT len: >248 aa; similar to SW:BCHI_CHLVI (EMBL:Z83933) FT Chlorobium vibrioforme magnesium-chelatase 38 kDa subunit FT (MG-protoporphyrin IX chelatase) BchI, 346 aa; fasta FT scores: opt: 441 z-score: 520.9 E(): 1.5e-21; 38.5% FT identity in 283 aa overlap. Contains Pfam match to entry FT PF01078 Mg_chelatase, Magnesium chelatase, subunit ChlI" FT /db_xref="GOA:Q8CJR9" FT /db_xref="HSSP:1G8P" FT /db_xref="InterPro:IPR011704" FT /db_xref="UniProtKB/TrEMBL:Q8CJR9" FT /protein_id="CAD55346.1" FT /translation="MPEPRILPYSRVVAQDELKLALELHHVVPRIGGVLMAGPRGTAKS FT TLVRAFALMAHGELPVTLPINATDDRVVGGWDLDALIRGEPRPQPGLLEDAADKGLLYV FT DEVNLLDDHLVDIILDVAATGVLSVQREGLDTAKYLSFGLVGTMNPEEGGLRPQLLDRF FT GLMVTAETLDATARHLLLRTVLDFELELEREDSAWLSAARRDDARTRDRLTAARRRVRD FT VDVPDHVLELCARAAERTEAVGQRGEIVAVLAARALAALEDADRVTPGHLRRVLPMALR FT HRRPEAVHGDTFDWEPDDEARLQDLFEV" FT misc_feature 61197..61880 FT /note="Pfam match to entry PF01078 Mg_chelatase, Magnesium FT chelatase, subunit ChlI, score 7.70, E-value 6.3e-09" FT RBS 62058..62062 FT CDS 62072..64039 FT /transl_table=11 FT /gene="SCO5278" FT /gene_synonym="SCCB12.02" FT /product="putative magnesium chelatase" FT /note="SCCB12.02, possible ion chelatase, len: 655 aa; FT similar to TR: SW:CHLD_SYNP7 (EMBL:AB003135) Synechococcus FT sp. magnesium-chelatase subunit ChlD (MG-protoporphyrin IX FT chelatase) ChlD, 677 aa; fasta scores: opt: 304 z-score: FT 269.4 E(): 1.5e-07; 26.6% identity in 688 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9FBR7" FT /protein_id="CAC04493.1" FT /translation="MAAVPPRPPTSPSPPPEGGIAGGAAPPDDPARRLGLALVCAAADP FT ALSGVLLVDLDPRLVDPVARLFGAVLAGAAEPARPPLVLGASDRDEDLWTRIRIRGGEH FT GITVRTEPGPLTEGDDADGAPPLVVVPDLARLSVAGMRAAVQLLGADVVTVERGGPRRT FT VRPRARWLAVCRSADVGRVSRHLLDRFAVRLSAAGLRLPGVREALAETGPRPEAGAAAG FT EGEALFAGLPAAWRSAAAGGVRPVPVGDAAIGRARELLGPDAGVRRELALLRLARTLAA FT LHGRPSASADDSDAAARLIGVAVPQDAPGRPESGPEPPGPAPGPTGLPGTVPERRAAGG FT DGRPRPRDGDRGLLDTGPAEGIGTAPGAAPSPADGSPYPEDEPAAARDTVPLSGPRRRS FT TGPVSTRGTVIGTRRATDLRDIAHVRTVREAAVHQRARGTERFTVSPVDLHSNVRAAAP FT ERVLVLLLDHTCRGGTGDGNWPEVLAPFLQWAYTSRAAVQVIEVGAADAADELRAGSFT FT ARGVLDPRVPGALYRRAGRATPLAHGVELAAHTLRRLLRRQGTGPAEAWLVVVTDGRGN FT VPLRVSHTGRLAGPVAAAGVEDAVEAAARIGAMDRTRLHVAVVDPGREPYGDLPYVLAD FT RLGAIVVDGRHAPGAEAAGE" FT RBS 64109..64112 FT CDS 64116..65354 FT /transl_table=11 FT /gene="SCO5279" FT /gene_synonym="SCCB12.03" FT /product="hypothetical protein SCCB12.03" FT /note="SCCB12.03, unknown, len: 412 aa" FT /db_xref="UniProtKB/TrEMBL:Q9FBR6" FT /protein_id="CAC04494.1" FT /translation="MARRPAASVLNLRRAQEPPAGLGGTDARPGARLEDGFAVLRVLRA FT DGADGLPGYRLQGWCGDLSVTCAAGPTRRPAPAVSLARLRQDGDGHYPSEVLRGIRLWS FT DNQYELAGWVNRIRARHGDDLRLVVWDDTGYDLPWELLLLPGDAAAGLAGGPLGAVIAV FT ARWTTVRDLSQGGLPAETGDCHGRVLGYLHQDMADDGRVFTSYAHRLHRRMTPFLSDLD FT TQDDRTGLVYLGCHGTYGEAVPGLTLGDRTWAELNGESMSVLRRDGSLVCLNACDSGRF FT VDNRAQGEEALRGFAELFLRKGAGGCIVSSGKVGDLEARAMARRLVREVAEHPRRPVVR FT TLRDFRVRALEEFGSLAELPRVRNDDGQVDVVGQKRVLRLLYAFMFHYYGHPGTALRLT FT AVDALGTEGGGGR" FT RBS 65340..65344 FT CDS 65351..68797 FT /transl_table=11 FT /gene="SCO5280" FT /gene_synonym="SCCB12.04" FT /product="putative ATP-binding protein" FT /note="SCCB12.04, possible ATP-binding protein, len: 1148 FT aa; similar to TR:CAB77406 (EMBL:AL160431) Streptomyces FT coelicolor putative ATP-binding protein SCD82.03, 966 aa; FT fasta scores: opt: 798 z-score: 834.6 E(): 0; 31.7% FT identity in 977 aa overlap. Contains match to Prosite entry FT PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9FBR5" FT /db_xref="InterPro:IPR011990" FT /db_xref="UniProtKB/TrEMBL:Q9FBR5" FT /protein_id="CAC04495.1" FT /translation="MSAAGRPSGQPLLIEPVVAWPRQAEAGGDYLVTVDLRGPLPSPDG FT TPAQWPHPEEEFTFTVTLDGAPHLDCSALGEPNVVLHRFGGTYGPARFRVSAGTDLGPA FT SLWLTVSNQWGVPVRKAELRCEIHAATGAAGVRAPGGPTPQNVPRMPLPRPSPATVRPD FT PDRRTVTISFAGPDRAWAAWIGDRLERRGVRVVPLRRGSPADVPPAALLRDLTLAPGRA FT LLVLNAPYFGDGTHQHEEWNAVLREVVAPHPARFAAVSVTGATLPSEVSLLAPAALHGL FT RAEEAERRLLERLGLPSEPVTEEAEARTGPRFPADAPGVWGAVPRRNTRFTGREALLDE FT IHDLLSGARPGEGMLTLHGMSGVGKTQLAAEYAHRLGPEYDVVWWVNAQERADCRRQLA FT ELAPRLGLRTGQEYGERLRAVRDALRRGEPCSRWLLVLDGADEPEEIEDLVPRGPGHVL FT VSSRNPEWGRYGSGLLEVPVYTRDESIAFIRRRAPGPTPAEADRLADALGDLPLLLAQT FT VGWLNDSDRSVDEYLALLADGDGTDGEARNVSEDFPSAFRTAWSILLAELRETAPESVV FT LLRLCTFFAPGLVPVHLLRSMPHDGLPDSVAGLLSDPRRWDRALGHLRRHSLVRVEPDP FT AEPERENLYVHRVVHQMAHQAMPEEIRRELVGVVRRALAAAGRGRPAAPEQWPRYAEIV FT PHLKYADVLATTDEAVQTLVLDCLRYLYLSGEYGAGVRLGGHATRIWRSLLGDQHPLVW FT ELTYHYANLLRAAGDFHRTMEIERAAVRHLSEQRGERDPDLLRALGGLAADLRGLGHYA FT EALEISQRVHGTYRELLGDQDTRTLNARNNVAVSLRLLGRYEDALSVDLPTLRDRRRLL FT GDRHPWTLSSETACAVDLRLLGRHEEALSRQDANWGLVRDTLGAHNRQTLLAAHNLALC FT HYAVGDTDEAAHHVGQALELGERVLGDSDPLVLMLLAGRSCLAREHGDLDLARALSERV FT VGRYEETLTAGHPYAAGARANHALLLHRAGEHDRAPALADAALADMDAAVGRDHPWTLG FT CALNAAILHGDAGDADRALTLSRDTAGTAARVLGSTHPFTLFAEVALAAELRVRGRRGQ FT SDAVQSQALEGLVAALGPQHPRTLSARARRAPFWDFEPQRT" FT misc_feature 66425..66448 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(68896..72714) FT /transl_table=11 FT /gene="SCO5281" FT /gene_synonym="SCCB12.05c" FT /product="putative 2-oxoglutarate dehydrogenase" FT /note="SCCB12.05c, probable 2-oxoglutarate dehydrogenase, FT len: 1272 aa; similar to TR:P96746 (EMBL:D84102) FT Corynebacterium glutamicum 2-oxoglutarate dehydrogenase (EC FT 1.2.4.2) OdhA, 1257 aa; fasta scores: opt: 4321 z-score: FT 3452.7 E(): 0; 54.8% identity in 1262 aa overlap and to FT SW:ODO1_ECOLI (EMBL:J01619) Escherichia coli 2-oxoglutarate FT dehydrogenase E1 component (EC 1.2.4.2) SucA, 933 aa; fasta FT scores: opt: 2568 z-score: 2056.0 E(): 0; 46.5% identity in FT 881 aa overlap. Contains Pfam matches to entries PF00198 FT 2-oxoacid_dh, 2-oxo acid dehydrogenases acyltransferase FT (catalytic domain) and PF00676 E1_dehydrog, Dehydrogenase FT E1 component. Possible alternative start codon at codon FT 156" FT /db_xref="GOA:Q9FBR4" FT /db_xref="HSSP:1E2O" FT /db_xref="InterPro:IPR011603" FT /db_xref="UniProtKB/TrEMBL:Q9FBR4" FT /protein_id="CAC04496.1" FT /translation="MSPQSPSNSSISTDTDQAGTAGKNPAAAFGANEWLVDEIYQQYLQ FT DPNSVDRAWWDFFADYKPGAAATPTAAGTVPTDAGSTPPAAPAPRAQAPAQPQAAAPAP FT APAKPAAAAPAAPAAPATKPAAAPAKPAAKPQAKAAAPAKDAGAAPEGPELVTLRGPAA FT AVAKNMNASLELPTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAI FT KAMPTMNHSFGEKDGKPTLVKPAHINLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFW FT QAYEDIVRRARDNKLTMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVILGVGSMDYPA FT EFQGTSQDTLNKLGISKVMTLTSTYDHRVIQGAASGEFLRQVANLLLGENGFYDDIFKA FT LRIPYEPVRWLKDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYQQRKHPDLD FT ITEHGLTLWDLEREFAVGGFAGKSLMKLRDILGVLRDSYCRTTGVEFMHIQDPKQRKWI FT QDRIERSHTKPEREEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVI FT DSAAESRLDEVVIGMAHRGRLNVLANVVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLG FT AEGTFTGLDGEQIKVSLVANPSHLEAVDPVLEGVSRAKQDIINKGGTDFTVLPVAIHGD FT AAFAGQGVVAETLNMSQLRGYRTGGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEA FT PIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLICYRRRGHNETDNPAFTQPLMYDL FT IDKKRSVRKLYTESLIGRGDITLEEAEQALQDYQGQLEKVFTEVREAVSQPASAEPSEP FT QAEFPVAVNTAITAETVKRIAESQVNIPDHITVHPRLLPQLQRRAAMVEDGTIDWGMGE FT TLAVGSLLLDGVPVRLTGQDSQRGTFGQRHAVVIDRETGDEFTPLLYLSEDQARYNVYN FT SLLSEYAVMGFEYGYSLARPDALVMWEAQFGDFVNGAQTVVDEFISSAEQKWNQTSGVT FT LLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPTLPSNYFHLLRWQVHNPHHKPLV FT VFTPKSMLRLKAAASKAEEFTTGQFRPVIGDDSVDPAAVKKVVFTAGKVYYDLDAERKK FT RGLTDTAIIRIERLYPLPGAELQAEIAKYPNAEKYLWAQEEPANQGAWPFIALNLIDHL FT DLAVGADVPHGERLRRISRPHGSSPAVGSAKRHQAEQEQLVREVFEA" FT misc_feature complement(70120..71103) FT /note="Pfam match to entry PF00676 E1_dehydrog, FT Dehydrogenase E1 component, score 166.60, E-value 4.1e-46" FT misc_feature complement(71551..72231) FT /note="Pfam match to entry PF00198 2-oxoacid_dh, 2-oxo acid FT dehydrogenases acyltransferase (catalytic domain), score FT 42.90, E-value 5.8e-12" FT misc_feature complement(72265..72528) FT /note="proline and alanine rich region. High G+C content: FT 88.63%" FT CDS complement(72999..74126) FT /transl_table=11 FT /gene="SCO5282" FT /gene_synonym="SCCB12.06c" FT /product="putative two-component system sensor kinase" FT /note="SCCB12.06c, possible two-component system sensor FT kinase, len: 375 aa; similar to SW:AFQ2_STRCO (EMBL:D10654) FT Streptomyces coelicolor sensor protein AfsQ2, 535 aa; fasta FT scores: opt: 344 z-score: 382.3 E(): 7.9e-14; 32.5% FT identity in 335 aa overlap. Contains Pfam matches to FT entries PF00672 DUF5, HAMP domain and PF00512 signal, FT Histidine kinase. Also contains possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q9FBR3" FT /db_xref="HSSP:1BXD" FT /db_xref="InterPro:IPR003660" FT /db_xref="UniProtKB/TrEMBL:Q9FBR3" FT /protein_id="CAC04497.1" FT /translation="MSSRGREAARRNPGPRTTGEPWGGVRPFSIKTKLGALVVTSVLIT FT TGLSVIAVHTKTELRFITVFSMIATLLITQFVAHSLTAPLDEMNAVARSISHGDYTRRV FT RENRRDELGDLAVTINRMADDLEAQDLQRKELVANVSHELRTPIAGLRAVLENIVDGVT FT EADPETMRTALGQTERLGRLVETLLDLSRLDNGVIPLRKRRFEVWPYLSGVLKEANMVA FT SARAGIASGSGSHSRTDVHLALDVFPPELTAHADPERIHQVVANLIDNAVKHSPPHGRV FT TVRARRGELPESLELEVLDEGPGIPRSEWRRVFERFNRGSVSRPHGPGSDGGTGLGLAI FT ARWAVDLHGGRIGVAESERGCRILITLPGLPSTSG" FT misc_feature complement(73023..73703) FT /note="Pfam match to entry PF00512 signal, Histidine FT kinase, score 173.10, E-value 4.7e-48" FT misc_feature complement(73743..73952) FT /note="Pfam match to entry PF00672 DUF5, HAMP domain, score FT 72.10, E-value 1.2e-17" FT CDS complement(74123..74857) FT /transl_table=11 FT /gene="SCO5283" FT /gene_synonym="SCCB12.07c" FT /product="putative two-component system response regulator" FT /note="SCCB12.07c, possible two-component system response FT regulator, len: 244 aa; similar to TR:Q9ZEP4 FT (EMBL:AJ131213) Streptomyces coelicolor response regulator FT CseB or SCE94.09, 234 aa; fasta scores: opt: 632 z-score: FT 771.1 E(): 0; 44.3% identity in 230 aa overlap and to FT SW:RESD_BACSU (EMBL:L09228), 240 aa; fasta scores: opt: 573 FT z-score: 699.9 E(): 1.6e-31; 39.7% identity in 234 aa FT overlap. Contains Pfam matches to entries PF00072 FT response_reg, Response regulator receiver domain and FT PF00486 trans_reg_C, Transcriptional regulatory protein, C FT terminal" FT /db_xref="GOA:Q9FBR2" FT /db_xref="HSSP:1B00" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9FBR2" FT /protein_id="CAC04498.1" FT /translation="MEQTQTSHNGTATQGAQRRVLVVEDDQTIVDAIATRLRAEGFLVQ FT TAGDGPSAVDTAEAWQPDLLILDIMLPGFDGLEVCRRVQAQRPVPVLMLTARDDETDML FT VGLGVGADDYMTKPFSMRELAARVHVLLRRVERAVVAASTPRSGILRLGELEIDHAQRR FT VRVRSEDVHLTPTEFDLLVCLANTPRAVLSREQLLAEVWDWADASGTRTVDSHIKALRR FT KIGAERIRTVHGVGYALETPTP" FT misc_feature complement(74150..74353) FT /note="Pfam match to entry PF00486 trans_reg_C, FT Transcriptional regulatory protein, C terminal, score FT 107.00, E-value 1.1e-30" FT misc_feature complement(74474..74806) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 122.60, E-value 7.2e-33" FT CDS complement(74971..75678) FT /transl_table=11 FT /gene="SCO5284" FT /gene_synonym="SCCB12.08c" FT /product="conserved hypothetical protein" FT /note="SCCB12.08c, hypothetical protein, len: 235 aa; FT similar to TR:Q9RVH7 (EMBL:AE001956) Deinococcus FT radiodurans hypothetical 24.5 kDa protein DR1052, 230 aa; FT fasta scores: opt: 403 z-score: 466.7 E(): 1.6e-18; 38.5% FT identity in 218 aa overlap and to SW:SPEE_ECOLI FT (EMBL:J02804) Escherichia coli spermidine synthase (EC FT 2.5.1.16) SpeE, 287 aa; fasta scores: opt: 173 z-score: FT 204.7 E(): 0.00063; 31.9% identity in 119 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9FBR1" FT /protein_id="CAC04499.1" FT /translation="MPLTTHDSPEAAEAPEVLDRREGPYGEVVLRRHGTLLQIIANGCF FT LMDTSDGRSERRLVDAAADALAASGGRTAPHLLIGGLGVGFSLAHAAADPRWGRIAVVE FT REGAIIDWHRTGPLAALSADALADPRAEIVEADLVEYVNETSDTYDALCLDIDNGPGWT FT VTEGNDGLYAPSGLAGCARLLRPGGVLAVWSAQPSPEFEETLRNAGFQQVRTEEIPVAR FT GVPDVVHIGVGPG" FT RBS complement(75686..75692) FT RBS 75850..75853 FT CDS 75857..78280 FT /transl_table=11 FT /gene="SCO5285" FT /gene_synonym="lon" FT /gene_synonym="SCCB12.09" FT /product="ATP-dependent protease" FT /note="SCCB12.09, lon, ATP-dependent protease, len: 807 aa; FT similar to SW:LON_MYCSM (EMBL:AF030688) Mycobacterium FT smegmatis ATP-dependent protease LA (EC 3.4.21.53) Lon, 779 FT aa; fasta scores: opt: 2550 z-score: 2489.6 E(): 0; 64.7% FT identity in 785 aa overlap. Contains Pfam matches to FT entries PF02190 LON, ATP-dependent protease La (LON) domain FT and PF00004 AAA, ATPases associated with various cellular FT activities (AAA) and matches to Prosite entries PS00017 FT ATP/GTP-binding site motif A (P-loop) and PS01046 FT ATP-dependent serine proteases, lon family, serine active FT site" FT /db_xref="GOA:Q9EVK2" FT /db_xref="HSSP:1RR9" FT /db_xref="InterPro:IPR003959" FT /db_xref="UniProtKB/TrEMBL:Q9EVK2" FT /protein_id="CAC04500.1" FT /translation="MAAESAAFTPLTLPVLPLDDEVVLPGMVVPLDLSDAEVRAAVEAA FT QAAARSEPGKPRVLLVPRIDGTHAATGVLGTVEQVGRLADGDPGALIRGRGRVRIGAGT FT TGPGAALWVEGTRVDETVPDPLPGQVAELVKEYKALATAWLRKRGAWQVVDRVQAIDDV FT SALADNSGYSPFLTTEQKVELLETTDPVARLKIATQQLRDHLAEQDVAETIAKDVQEGV FT DKQQREFLLRRQLEAVRKELREINGEQEGEESDDYRARVEAADLPEKVREAALKEVDKL FT ERSSDQSPEGSWIRTWLDTVLEMPWSERTEDAYDIQGAQAVLDAEHAGLEDVKERITEY FT LAVRKRRGDRGLGVVGGRRGGAVLALVGPPGVGKTSLGESVAHAMGRKFVRVALGGVRD FT EAEIRGHRRTYVGALPGRIVRAIKEAGSMNPVVLLDEIDKVGSDFRGDPAAALLEVLDP FT AQNHTFRDHYLEVELDLSDVVFLATANVLEAIPEALLDRMELVRLDGYTEDEKVVIARD FT HLLPRQLERAGLDDDEVTVDEGALRKLAGEYTREAGVRTLERSIARLLRKVAAQHELGE FT RELPFTVTEGDLRSLIGRPHHVPESAQDPAERRTAVPGVATGLAVTGAGGDVLYVEASL FT ADPETGAAGLTLTGQLGDVMKESAQIALSFLRSHGAELELPVGDLKDRGAHIHFPAGAV FT PKDGPSAGVTMTTALASLLSGRLVRTDVAMTGEVSLTGRVLPIGGVKQKLLAAHRAGIT FT TVIIPKRNEPDLDDVPAQVLDKLDVHAVTDVRQVLELALAPATNGAEREVPVAA" FT misc_feature 75890..76465 FT /note="Pfam match to entry PF02190 LON, ATP-dependent FT protease La (LON) domain, score -18.10, E-value 0.00014" FT misc_feature 76943..77530 FT /note="Pfam match to entry PF00004 AAA, ATPases associated FT with various cellular activities (AAA), score 103.40, FT E-value 4.6e-27" FT misc_feature 76958..76981 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 77945..77971 FT /note="PS01046 ATP-dependent serine proteases, lon family, FT serine active site" FT CDS complement(78357..79184) FT /transl_table=11 FT /gene="SCO5286" FT /gene_synonym="SCCB12.10c" FT /product="putative secreted hydrolase" FT /note="SCCB12.10c, probable secreted hydrolase, len: 275 FT aa; similar to SW:LYCM_STRGL (EMBL:M30645) Streptomyces FT globisporus lysozyme M1 precursor (EC 3.2.1.17) Acm, 294 FT aa; fasta scores: opt: 828 z-score: 944.2 E(): 0; 45.7% FT identity in 291 aa overlap and to TR:Q9RJP9 (EMBL:AL132991) FT Streptomyces coelicolor putative lysozyme precursor FT SCF55.15, 279 aa; fasta scores: opt: 1425 z-score: 1618.9 FT E(): 0; 75.2% identity in 270 aa overlap. Contains Pfam FT match to entry PF01183 Glyco_hydro_25, Glycosyl hydrolases FT family 25 and 2x matches to Prosite entry PS00017 FT ATP/GTP-binding site motif A (P-loop). Also contains FT possible N-terminal region signal peptide sequence FT (possibly cleavable)" FT /db_xref="GOA:Q9FBR0" FT /db_xref="HSSP:1JFX" FT /db_xref="InterPro:IPR018077" FT /db_xref="UniProtKB/TrEMBL:Q9FBR0" FT /protein_id="CAC04501.1" FT /translation="MLVHRSGSARGRRFAVTGILLAAFSLVFTLPADAASAADVPARGS FT AHMGMGVAAHDGEHGTPVPGRAAQTEGVDVSSHQGNVAWSTLWNSGVKWAYAKATEGTY FT YTNPYFAQQYNGSYNVGMIRGAYHFATPDTTSGATQANYFVDHGGGWSRDGKTLPGALD FT IEWNPYGATCYGKSQSGMVSWIRDFLNTYKARTGRDAVIYTATSWWTQCTGNYGGFAAS FT NPLWIARYASTVGTLPAGWGYYTMWQYTSSGPTVGDHNKFNGALDRVVALANG" FT misc_feature complement(78645..78980) FT /note="Pfam match to entry PF01183 Glyco_hydro_25, Glycosyl FT hydrolases family 25, score 104.90, E-value 1.5e-27" FT misc_feature complement(78654..78677) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(78714..78737) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(79191..79195) FT CDS 79433..79927 FT /transl_table=11 FT /gene="SCO5287" FT /gene_synonym="SCCB12.11" FT /product="putative MarR-family transcriptional regulator" FT /note="SCCB12.11, possible MarR-family transcriptional FT regulator, len: 164 aa; similar to TR:Q9RL39 (EMBL: FT AL121596) Streptomyces coelicolor MarR-family protein FT SCF51.25, 148 aa; fasta scores: opt: 237 z-score: 290.2 FT E(): 1.1e-08; 37.6% identity in 141 aa overlap and to FT SW:YXAD_BACSU (EMBL:AB005554) Bacillus subtilis FT hypothetical transcriptional regulator on AsnH-GntR FT intergenic region YxaD, 143 aa; fasta scores: opt: 234 FT z-score: 286.9 E(): 1.6e-08; 35.7% identity in 140 aa FT overlap. Contains Pfam match to entry PF01047 MarR, MarR FT family and possible helix-turn-helix motif at residues FT 72..93 (+3.73 SD)" FT /db_xref="GOA:Q9FBQ9" FT /db_xref="InterPro:IPR000835" FT /db_xref="UniProtKB/TrEMBL:Q9FBQ9" FT /protein_id="CAC04502.1" FT /translation="MHEDGNGGGRGGESHLSGSGVNQPEFLALERELTVLLRRARANQG FT EMAREVHPDLESSAYGLLVRLGECGGQRATDLAAFIGVGKATMSRQLRALEELGLVARE FT PDPADGRAWLVTLTPEGQERVGRVREARRARYARRLAGWDPREVTELARLLHELNRGME FT K" FT misc_feature 79595..79906 FT /note="Pfam match to entry PF01047 MarR, MarR family, score FT 99.30, E-value 7.3e-26" FT CDS complement(79949..80740) FT /transl_table=11 FT /gene="SCO5288" FT /gene_synonym="SCCB12.12c" FT /product="hypothetical protein SCCB12.12c" FT /note="SCCB12.12c, unknown, len: 263 aa" FT /db_xref="UniProtKB/TrEMBL:Q9FBQ8" FT /protein_id="CAC04503.1" FT /translation="MRTELVSEPGLADQPNEDFASVGLPASGQGGSLVVLDGVTPPRTA FT TGCLHSVPWFTARLGGALTELTVSLPDLPLAEALSRGIARTAAAHAETCDLSHPRTPQA FT TVVLARWSAAAFEYLVLSDSALLLEAPDGTLTPVLDDRLARLPRSALVSDAVIDAGLRN FT KEGGFFTAAADPAVAARAVTGVLPRGAVRTLAALTDGAARWVEKFGEGDWADCLALVRK FT QGAQALVDRVRELERADAADGRAFLGRSKTHDDATVVYAEL" FT CDS 81250..84189 FT /transl_table=11 FT /gene="SCO5289" FT /gene_synonym="SCCB12.13" FT /gene_synonym="SC6G9.44c" FT /gene_synonym="cvnA5" FT /product="putative two component sensor kinase" FT /note="SCCB12.13, cvnA5, hypothetical protein (fragment), FT len: >191 aa; similar to C-terminal region of TR:O86525 FT (EMBL:AL031124) Streptomyces coelicolor hypothetical 139.7 FT kDa protein SC1C2.25c, 1329 aa; fasta scores: opt: 146 FT z-score: 152.5 E(): 0.5; 25.3% identity in 186 aa overlap. FT Contains possible hydrophobic membrane spanning region" FT /note="SC6G9.44c, possible sensor kinase, len: 806 aa; weak FT similarity to part of TR:O33492 (EMBL:AJ000330), StyS, FT Pseudomonas sp. strain Y2 styrene sensor kinase (982 aa), FT fasta scores; opt: 256 z-score: 230.5 E(): 1.6e-05, 24.7% FT identity in 543 aa overlap. Similar to parts of other FT S.coelicolor hypothetical proteins e.g. TR:O86525 FT (EMBL:AL031124) S.coelicolor hypothetical protein (1329 aa) FT (31.5% identity in 821 aa overlap). Contains 11x degenerate FT E(K/T)A repeats between codons 555 and 587. Contains FT probable coiled-coil from 251 to 295 (45 residues) (Max FT score: 1.500, probability 0.95). Contains Pfam match to FT entry PF00672 DUF5, Domain found in bacterial signal FT proteins and to entry PF00512 signal, Signal FT carboxyl-terminal domain" FT /db_xref="GOA:Q8CJR8" FT /db_xref="InterPro:IPR003660" FT /db_xref="UniProtKB/TrEMBL:Q8CJR8" FT /protein_id="CAD55347.1" FT /translation="MGSAERTPGTSTPPQPPEAPVGKGRATHVRNRLIVAVAVVAAAVA FT GAGAPSVVAASGQLHDSQELVTLAEQTQGALTLAHSLADERDEVTPYIAAGRPKSKAPS FT EQRSARVDRQVEELRADTDTPASLREDLDAVAALRRAALTGKSTALEAHQAYSEAITEL FT HALAEKLGEEMPPRAGSGAYALAELDTAVQQAAATRGLLLAALNVPSTTETVIDPVTGL FT PTETTTSSDADAEQRDALAAAAQQARVRSDAALADFREGAPKEARGSFDATVAGPEVNS FT AEKYLAGLTDEPTLSDRDLGTSTKRLDAALSARVDAMRGAESALYEKRVAALEQLRDDD FT VTALEIRIAVLGALILLAVGIATALARTLTRPLSVLRRGSARLAGAADPTTEEPVAFTG FT RNDEFAQVVRSVNALHTHAATLAGRVATLESDRKHLVGQRQKMADAREELRTELAESAA FT QLEVVRKSIGSTFVSLALRTLGLVERQLAVIESLEEREQDPDRLATLFKLDHFATVMRR FT HSENLLVLAGTEHVQHSASPVPLVDVVRAAVSEIERYERVRIAALPPHAHVAGFAADDL FT SHLLAELMENATSFSPPDLPVEVSGWLLENGEVMLSVQDEGIGMATERLQRLNARLTDF FT DPDAPYDQEGEDGLGLGLYVVARLAHRHGARVRLREQKQGGVAAVVVLPSPLLAAAPPA FT ALAPTVPVSDGTGTFSLPGADAEANSNVLHGRTEKSEAAEKSETAERAGTAEKAEKAGT FT AGKSETAEQGAGEDAGPGAEPVIDPLVASAEEAVRRAEADASHADAPQTPEPDEREDPA FT GPVPPEPARETVSAQDGPAPGSDLPDDATMALFLPALAEPETRPETDPGPYAIGPDAHD FT RVPDTAEETGGQQEPAPSTRAEPVTDKGLPKRTPKLTTPAAVPRPRTSGSVDADALRRR FT LGGFRRGAEAGRRDVEAEIADRPGQDQAPDTGAGTTEEATGGTVEEASS" FT misc_feature 82288..82509 FT /note="Pfam match to entry PF00672 DUF5, Domain found in FT bacterial signal proteins, score 31.30, E-value 2.2e-05" FT misc_feature 82705..83301 FT /note="Pfam match to entry PF00512 signal, Signal FT carboxyl-terminal domain, score 3.30, E-value 1.6e-05" FT repeat_region 83431..83528 FT /note="repeat 3; 11x degenerate 9 bp repeats" FT CDS 84264..84716 FT /transl_table=11 FT /gene="SCO5290" FT /gene_synonym="SC6G9.43c" FT /gene_synonym="cvnB5" FT /product="hypothetical protein" FT /note="SC6G9.43c, cvnB5, conserved hypothetical protein, FT len: 150 aa; similar to hypothetical proteins from S. FT coelicolor and Mycobacterium tuberculosis e.g. TR:O86524 FT (EMBL:AL031124) S.coelicolor hypothetical protein (173 aa), FT fasta scores; opt: 316 z-score: 394.7 E(): 1.2e-14, 48.1% FT identity in 131 aa overlap and TR:O50393 (EMBL:AL009198) FT Mycobacterium tuberculosis hypothetical protein (130 aa) FT (36.7% identity in 120 aa overlap)" FT /db_xref="InterPro:IPR004942" FT /db_xref="UniProtKB/TrEMBL:Q9XAD9" FT /protein_id="CAB45634.1" FT /translation="MPGIRSVAVVSSDGLLLLSSDPGRNEEARQARETPRAGPRGSAAD FT LATVVSGVGSLTVGAARLMDFGPVKHTMVAMDEGSLFVMSISDGSLLGVHGSAECDMSV FT VAYHMALFVGRAGHVLTPELRTELRKSLESESSESSVSSEPTGSAR" FT CDS 84713..85165 FT /transl_table=11 FT /gene="SCO5291" FT /gene_synonym="SC6G9.42c" FT /gene_synonym="cvnC5" FT /product="hypothetical protein" FT /note="SC6G9.42c, cvnC5, conserved hypothetical protein, FT len: 150 aa; similar to hypothetical proteins of varying FT length (divergent at the N-terminus) from S. coelicolor and FT Mycobacterium tuberculosis e.g. TR:O86523 (EMBL:AL031124) FT S.coelicolor hypothetical protein (132 aa), fasta scores; FT opt: 250 z-score: 312.1 E(): 4.7e-10, 43.7% identity in 135 FT aa overlap and TR:O50392 (EMBL:AL009198) Mycobacterium FT tuberculosis hypothetical protein (122 aa) (37.4% identity FT in 131 aa overlap)" FT /db_xref="InterPro:IPR007995" FT /db_xref="UniProtKB/TrEMBL:Q9XAE0" FT /protein_id="CAB45633.1" FT /translation="MSSSPGKPGTNGRGNLPVRGADRKPARVRPYSLTGGRTRFGHVLL FT VETFVGATAGTAALEAAEERRELTNGGLTSRVMPEMRAIVELCRRMRTVAEIAALLKMP FT LGVVRVLLSDLADQGKIRVYGTGTGHGTGRPDRALLERVLSGLRRL" FT CDS 85212..85787 FT /transl_table=11 FT /gene="SCO5292" FT /gene_synonym="SC6G9.41c" FT /gene_synonym="cvnD5" FT /product="putative ATP/GTP-binding protein" FT /note="SC6G9.41c, cvnD5, possible ATP/GTP-binding protein, FT len: 191 aa; highly similar to others from S.coelicolor FT e.g. TR:O86519 (EMBL:AL031124) S.coelicolor possible FT ATP/GTP-binding protein (174 aa), fasta scores; opt: 766 FT z-score: 918.0 E(): 0, 68.0% identity in 169 aa overlap. FT Although many of the presumed homologues start at the FT equivalent of codon 18 in this CDS, there is no possible FT initiation codon in this case. Also similar to hypothetical FT proteins from other organisms e.g. TR:O5039 (EMBL:AL009198) FT Mycobacterium tuberculosis hypothetical protein (193 aa) FT (63.6% identity in 173 aa overlap). Similar to the FT C-terminal half of TR:O26694 (EMBL:AE00084) FT Methanobacterium thermoautotrophicum conserved protein (393 FT aa) (29.5% identity in 173 aa overlap). Contains PS00017 FT ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9XAE1" FT /db_xref="InterPro:IPR004130" FT /db_xref="UniProtKB/TrEMBL:Q9XAE1" FT /protein_id="CAB45632.1" FT /translation="MQPWQTDPTRAPVATKIVVAGGFGVGKTTLVTAVSEITPLQTEAL FT MTEASEETDDLTATPGKLTTTVAMDFGRITLDDDLVLYLFGTPGQQRFWFMWDDLVRGA FT IGAVVLADTRRLKDCWPALDYFESCGLPYVVAVNHFDGSELFEAEDVREALTIPAHIPV FT MIMDARRRISAIETLLSLVGHALDETPE" FT misc_feature 85272..85295 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 85846..87108 FT /transl_table=11 FT /gene="SCO5293" FT /gene_synonym="SC6G9.40c" FT /product="putative oxygenase subunit" FT /note="SC6G9.40c, possible oxygenase subunit, len: 420 aa; FT similar to Pseudomonas spp. styrene monoxygenase large FT subunits e.g. TR:O06834 (EMBL:Z92524), styA, Pseudomonas FT fluorescens main component of styrene monooxygenase (415 FT aa), fasta scores; opt: 481 z-score: 542.1 E(): 7.3e-23, FT 31.2% identity in 417 aa overlap. It has no neighbouring FT CDS similar to the monoxygenase small subunit. The FT C-terminus overlaps the C-terminus of the downstream ORF on FT the opposite strand" FT /db_xref="GOA:Q9XAE2" FT /db_xref="InterPro:IPR003042" FT /db_xref="UniProtKB/TrEMBL:Q9XAE2" FT /protein_id="CAB45631.1" FT /translation="MRKILVVGAGQSGLQLALGLQSHGYEVTLMSNRTADEIRTGRVMS FT TQCMFHTALQHERDLQLNFWESQAPKIEGLGVSVAAPGSFDPGPSQRAIDWLGHLDGFA FT QSVDQRVKMAGWMETFAQRGGQLVIHGAAVGDLDYFSRAYDLVLVSAGKGELVQMFGRD FT AERSPYSEPQRALAVAYVHGMGPRPEHPETEAVRCNLVPGVGEMFIMPTFTTSGRADIL FT FWEGIPGGPLDAFKDVKDPAEHLSLTLELMEKFLPWEYARATKVELTDAGGTLAGRYAP FT TVRNPVGRLPGGGAVLGVADVVVANDPITGQGSNSASKCAASYLASIIEHGDQEFDETW FT MRQTFDRYWETAQHVTKWTNTMLAPPPEHILNLFGAATQLQPIADRFANGFNDPSDFEN FT FFYDPAKTEGYLAEVSGAAGA" FT CDS complement(87072..88247) FT /transl_table=11 FT /gene="SCO5294" FT /gene_synonym="SC6G9.39" FT /product="putative secreted protein" FT /note="SC6G9.39, probable secreted protein, len: 391 aa; FT similar to mycobacterial hypothetical proteins e.g. FT TR:O69580 (EMBL:AL022602) Mycobacterium leprae probable FT secreted protein (374 aa), fasta scores; opt: 347 z-score: FT 354.0 E(): 2.2e-12, 29.1% identity in 337 aa overlap. FT Similar to part of Listeria p60 attachment/invasion FT proteins e.g. SW:P60_LISWE (EMBL:M80354) Listeria FT welshimeri protein p60 precursor (524 aa) (37.8% identity FT in 98 aa overlap). Similar to other putative secreted FT proteins from S.coelicolor e.g. (EMBL:AL049497), FT SC6G10.08C, S.coelicolor putative secreted protein (338 aa) FT (38.3% identity in 342 aa overlap). Contains possible FT N-terminal signal sequence. The C-terminus overlaps the FT C-terminus of the downstream ORF on the opposite strand. FT Contains probable coiled-coils from 43 to 98 (56 residues) FT ( Max score: 1.580, probability 0.99) and from 164 to 201 FT (38 residues) (Max score: 1.531, probability 0.97). FT Contains Pfam match to entry PF00877 NLPC_P60, NLP/P60 FT family (domain of unknown function)" FT /db_xref="InterPro:IPR000064" FT /db_xref="UniProtKB/TrEMBL:Q9XAE3" FT /protein_id="CAB45630.1" FT /translation="MSGRLLRLVCTAALTAGIVLAPVPAAAGPGPGPGPAEGAAGDRTV FT AGLLTDLQRLYREAERATETYNGTEERLKRQRARVLRLNAELTRTRLSLRDSRGAAGRL FT ARQQYQNSSDFSPYLRLLLARDPQHALDQGHVIGRLSEERAETVGRLTGDTKKADELAG FT RARAALARQAALAERQERERDGVRERLRAVEELLASLTPEQLAALAELEKSGIAEEQER FT FLASGALGDDAKPSAGGESAVRFAVEQLGKPYQWGAEGPASYDCSGLTSVAWERAGTPI FT PRTSQEQWARLDHVPLDELRPGDLVVYFPEATHVAMYLGDGMVVQAPRPGADVKVSPIA FT ANPVLGAVRPDPGGEPVLRYTPPRLPAGATNGSDEGYAASYAPAAPETSAR" FT misc_feature complement(87198..87512) FT /note="Pfam match to entry PF00877 NLPC_P60, NLP/P60 FT family, score 93.50, E-value 4.1e-24" FT CDS complement(88351..88674) FT /transl_table=11 FT /gene="SCO5295" FT /gene_synonym="SC6G9.38" FT /product="hypothetical protein" FT /note="SC6G9.38, hypothetical protein, len: 107 aa; unknown FT function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition" FT /db_xref="UniProtKB/TrEMBL:Q9XAE4" FT /protein_id="CAB45629.1" FT /translation="MKSEDTPFEGGPMDGRVLPVLVGMTGHPPKTYRIPVPDPDGGPPT FT VLVYRRVPRDSRGGLRFARWKYAYAPEGAKGSGRKWPWSKPERPSAAEPDATPGGKPDD FT ADG" FT CDS complement(88745..89398) FT /transl_table=11 FT /gene="SCO5296" FT /gene_synonym="SC6G9.37" FT /product="putative tetR-family transcriptional regulator" FT /note="SC6G9.37, possible tetR-family transcriptional FT regulator, len: 217 aa; similar to many hypothetical FT proteins, especially from mycobacteria e.g. TR:Q49662 FT (EMBL:U00012) Mycobacterium leprae hypothetical protein FT (242 aa), fasta scores; opt: 216 z-score: 270.8 E(): FT 9.4e-08, 28.8% identity in 222 aa overlap. Weak similarity FT to some putative transcriptional regulators. Contains FT probable helix-turn-helix motif at aa 39-60 (Score 1937, FT +5.78 SD). Contains Pfam match to entry PF00440 tetR, FT Bacterial regulatory proteins, tetR family" FT /db_xref="GOA:Q9XAE5" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9XAE5" FT /protein_id="CAB45628.1" FT /translation="MTPQAPTPAYRRLSVEERRVQLLDAALALFAHRPPEEVSLDDVAE FT QAGVSRPLVYRYFPGGKQQLYEAALSSAADELRLCFDEPRKGPLLARLSRALDRYLTFV FT DEHDTGFSALLRGGSVVETSQTSGIVDGVRRAAADHIMRHLDVAEPGPRLRMTVRMWIT FT AVEAASLIWLDEDKQPPFDELRDWLVEQFLAVLTVTARRDPQSAALVETLAADL" FT misc_feature complement(89192..89335) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 27.50, E-value FT 7.2e-06" FT repeat_region 89683..89703 FT /note="20 bp imperfect inverted repeat (1 mismatch)" FT repeat_region complement(89683..90580) FT /note="insertion element IS1650" FT CDS join(89707..90117,90114..90560) FT /pseudo FT /transl_table=11 FT /gene="SCO5297" FT /gene_synonym="SC6G9.36c" FT /gene_synonym="SC6G9.35c" FT /product="putative transposase" FT /note="SC6G9.36c, probable transposase ORF1, len: 136 aa; FT similar to parts of many putative transposases e.g. FT TR:Q44424 (EMBL:M55562) Agrobacterium tumefaciens IS427 ORF FT 4 (137 aa), fasta scores; opt: 334 z-score: 436.7 E(): FT 5.4e-17, 50.8% identity in 118 aa overlap. Similar to FT TR:O69927 (EMBL:AL02386) S.coelicolor IS1648 putative FT transposase (141 aa) (60.5% identity in 119 aa overlap). FT May be translated by frameshifting into the downstream ORF" FT /note="SC6G9.35c, probable transposase ORF2, len: 148 aa; FT similar to parts of many putative transposases e.g. FT TR:Q46487 (EMBL:X75973) Clavibacter xyli insertion sequence FT IS1237 transposase (308 aa), fasta scores; 42.1% identity FT in 171 aa overlap. Similar to part of TR:O69928 FT (EMBL:AL023861) S.coelicolor IS1648 putative transposase FT fragment (152 aa) (52.7% identity in 150 aa overlap). May FT be translated as a result of frameshifting from the FT upstream ORF" FT misc_feature 90063..90068 FT /note="possible ribosomal frameshift site" FT repeat_region complement(90560..90580) FT /note="20 bp imperfect inverted repeat (1 mismatch)" FT CDS complement(90576..91514) FT /transl_table=11 FT /gene="SCO5299" FT /gene_synonym="SC6G9.34" FT /product="putative membrane protein" FT /note="SC6G9.34, possible membrane protein, len: 312 aa; FT unknown function, similar to proteins from Mycobacterium FT leprae and Mycobacterium tuberculosis e.g. TR:O33063 FT (EMBL:Z99494) Mycobacterium leprae hypothetical protein FT (341 aa), fasta scores; opt: 316 z-score: 387.1 E(): FT 3.1e-14, 27.1% identity in 255 aa overlap (divergent at FT C-terminus). Contains hydrophobic, possible FT membrane-spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9XAE8" FT /protein_id="CAB45625.1" FT /translation="MTTLTEADALEGLRDALGLLKDREQVAERLLDSSAKHSFDPDKEL FT DWDAPFEDGKWFWPPELVSLYDTPMWQRMSEEQRIALSQHEAAALASLGIWFELILMQL FT LVRHIYDKAATSAHVRYALTEIEDECRHSKMFARLISRGETPWYPVSPVHQHLGRLFKT FT ISTTPGSFTATLLGEEVLDWMQRLTFPDERVQPLIRGVTRIHVVEEARHVRYAREELRR FT QMVTAPKWSQEFTRVTSGEFARVFSKAFINPEVYTNVGLDKREALAQVRASGHRKEIMQ FT TGAKRLTDFLDDIGVLRGAGRKLWRSSGLLA" FT CDS complement(91662..92168) FT /transl_table=11 FT /gene="SCO5300" FT /gene_synonym="SC6G9.33" FT /product="conserved hypothetical protein" FT /note="SC6G9.33, hypothetical protein, len: 168 aa; unknown FT function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Alternative start codon present at codon 6. Similar to FT TR:Q9A5F4 (EMBL:AE005918) Caulobacter crescentus FT hypothetical protein CC2496, 185 aa; fasta scores: opt: 573 FT Z-score: 686.8 E(): 1.3e-30; 52.532% identity in 158 aa FT overlap" FT /db_xref="UniProtKB/TrEMBL:Q9XAE9" FT /protein_id="CAB45624.1" FT /translation="MTEDAVHELAQVNIARLKAPLDSPQLKDFVDALEPVNAAADAADG FT FVWRLQSEGGDATDIPVFGDSWLIVNLTMWRDADALTAFMYQGRHREMLARRREWFERP FT AEAVTALWWVPAGHRPTVAEAESRLRHLRTHGPTPYAFTLRTSYPAGASEPVPGEVPEG FT LDCSV" FT CDS complement(92214..93671) FT /transl_table=11 FT /gene="SCO5301" FT /gene_synonym="SC6G9.32" FT /product="putative secreted penicillin-binding protein" FT /note="SC6G9.32, possible secreted penicillin-binding FT protein, len: 485 aa; similar to many e.g. to the FT C-terminal end of SW:PBPC_BACSU (EMBL:D38161), PbpC, FT Bacillus subtilis penicillin-binding protein 3 (668 aa), FT fasta scores; opt: 422 z-score: 451.6 E(): 8e-18, 27.6% FT identity in 384 aa overlap. Similar to putative FT penicillin-binding proteins from mycobacteria e.g. FT TR:P71586 (EMBL:Z80233) Mycobacterium tuberculosis PpbA FT homologue (491 aa) (42.8% identity in 495 aa overlap). FT Contains a hydrophobic, possible membrane anchor at the FT N-terminus. Contains Pfam match to entry PF00905 FT Transpeptidase, Penicillin binding protein transpeptidase FT domain and PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9XAF0" FT /db_xref="InterPro:IPR001460" FT /db_xref="UniProtKB/TrEMBL:Q9XAF0" FT /protein_id="CAB45623.1" FT /translation="MTRNIRHAAVFCALLLVALVVNAARVQIVQKPEYDDNPANRRPDI FT ARYQQPRGDILVGGGAVTGSRDTGEHLRFERTYADGPMYAPITGFASQAYGTTLLEHAE FT DGLLSGADPMLAPLPLWNDVTGAHNPGGDVVTTIHGAAQRAAFEGLGGRKGAVAAIEPA FT TGRVLALVSTPSYDPQLLSGNSAAATRTWKRLNADPDKPMLNRAVSRTYPPGSTFKVVT FT AAAALEAGVIRDLDAPTRSPDPYTLPGTRTKLTNEADGCRNASLREAFEWSCNTVFAKL FT GVDVGVRGMTAMAEAFGFNDDGLRVPFPVARSTFDTSVDRAQLGLSSIGQYNTRATPLQ FT MATVAAAVAGGGQVRSPYLVERTLRAGGSLVAAAGSRPSREVMRPSTAALLKELMTGVV FT DKGTGAKAAIPGATVGGKTGTAQHGVGNSGTPYAWFISWARGAGDIEPKVAVAVVVEGT FT ASDRQGVSGGGLAAPIARAVMEAVLGG" FT misc_feature complement(92241..93254) FT /note="Pfam match to entry PF00905 Transpeptidase, FT Penicillin binding protein transpeptidase domain, score FT 249.30, E-value 5.5e-71" FT misc_feature complement(92418..92441) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(93688..95028) FT /transl_table=11 FT /gene="SCO5302" FT /gene_synonym="SC6G9.31" FT /product="putative integral membrane cell-cycle protein" FT /note="SC6G9.31, probable integral membrane cell-cycle FT protein, len: 446 aa; similar to members of the ftsW FT (Escherichia coli cell division)/rodA (Escherichia coli FT cell shape)/spoVE (Bacillus subtilis spore formation) FT family e.g. SW:SP5E_BACSU (EMBL:X51419), spoVE, Bacillus FT subtilis stage V sporulation protein E (366 aa), fasta FT scores; opt: 461 z-score: 525.9 E(): 5.8e-22, 33.4% FT identity in 371 aa overlap. Highly similar to proteins from FT mycobacteria e.g. TR:FTSW_MYCLE (EMBL:Z70722), ftsW, FT Mycobacterium leprae probable cell division protein (465 FT aa) (46.5% identity in 430 aa overlap). Contains FT hydrophobic, possible membrane-spanning regions. Contains FT Pfam match to entry PF01098 FTSW_RODA_SPOVE, Cell cycle FT protein" FT /db_xref="GOA:Q9XAF1" FT /db_xref="InterPro:IPR001182" FT /db_xref="UniProtKB/TrEMBL:Q9XAF1" FT /protein_id="CAB45622.1" FT /translation="MAQADTPAPVARLPRRRGIELALILMAVLLSVFGYCNVGLAQHDA FT LPPGAAGYGAGLGVLALLAHLAVRLRAPYADPLLLPIGVLLNGLGLVLIYRLDLETPGD FT RAAPTQLVWSTLGVALFIVVVLLLRDHRVLQRYAYVCVAAALALLTVPIFFPAVNGARI FT WIRIEGFSIQPGEFAKVLLAVFFAAYLAANRSALAYAGRRVWRLQLPTGRVLGPILAVW FT LVSVGVLVLERDLGTSLLFFGLFVVLLYVATGRTGWIAVGLLLASLGAVAVGWLEPHVH FT SRVEDWLHPFASIEAGHGPNQLAQSLFAFAAGGVTGTGLGLGHSVLIGFAVKSDFILAT FT AGEELGFLGLSAVFLLYGLLVERGYRAGLGARDPFGRLLAVGLSSIVALQVFVIAGGVT FT GLIPLTGMAMPFLAQGGSSVVTNWAIVALLIRVSHAARSQAGGRAEP" FT misc_feature complement(93715..94803) FT /note="Pfam match to entry PF01098 FTSW_RODA_SPOVE, Cell FT cycle protein, score 266.90, E-value 2.6e-76" FT CDS complement(95105..95572) FT /transl_table=11 FT /gene="SCO5303" FT /gene_synonym="SC6G9.30" FT /product="putative membrane protein" FT /note="SC6G9.30, possible membrane protein, len: 155 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Contains hydrophobic, possible membrane-spanning region FT near the N-terminus" FT /db_xref="InterPro:IPR017909" FT /db_xref="UniProtKB/TrEMBL:Q9XAF2" FT /protein_id="CAB45621.1" FT /translation="MSPLSAPASRSPLVRGLATALAAGALATAVAVTPAAANDEWGGDA FT GSTSAVTGGGNRGGDGGGSGGGAWGGSDGRQEQGRYRGVVTADRLALRTSPSRGADVIR FT YARRGEVVSIYCKTPGSRVQGNPLWYLLTDGTWAWGAARYIDNIGPAPRWC" FT CDS complement(95680..96924) FT /transl_table=11 FT /gene="SCO5304" FT /gene_synonym="SC6G9.29" FT /product="putative sensor-like histidine kinase" FT /note="SC6G9.29, possible sensor-like histidine kinase, FT len: 414 aa; similar to many sensor histidine kinases from FT two-component systems e.g. (EMBL:AJ13121), CseC, FT S.coelicolor sensory histidine kinase of two-component FT system regulating sigE transcription (507 aa), fasta FT scores; opt: 966 z-score: 1051.7 E(): 0, 44.3% identity in FT 429 aa overlap. This protein does not have an obvious FT response regulator companion. Similar to part of another FT lone sensor-like histidine kinase TR:O05890 (EMBL:Z95121), FT Mycobacterium tuberculosis sensor-like histidine kinase FT (567 aa) (33.8% identity in 397 aa overlap). Contains FT hydrophobic, possible membrane-spanning regions. Contains FT Pfam matches to entry PF00672 DUF5, Domain found in FT bacterial signal proteins and to entry PF00512 signal, FT Signal carboxyl-terminal domain. Contains possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9XAF3" FT /db_xref="InterPro:IPR003660" FT /db_xref="UniProtKB/TrEMBL:Q9XAF3" FT /protein_id="CAB45620.1" FT /translation="MRLALPRWTGPLAVKAAVFITVMCCGLAALLGVLVHVSVTNRTVG FT QARDAALSRLGEATESYEAGDPLRRGAGIDPAGLPRQLRELAASGRRGTMLAEYAGRPT FT MWAAGPADGGRALAVRVDHSQGQATIDGLDGTLVWSSALAIGATLLVGAFAVTRVTRRL FT HTTARVARRISAGDLDARVGDPRAQDPTRPQDEVASVAAALDSMASSLQGKLLAEQRFT FT ADVAHELRTPLTGLHAAAELLPPGRPTELVRDRVAALRTLTEDLLEISRLESGRERPAT FT EPEELGALVRRVLRGSGTDTRVDVVRDARVETDRRRLERVLGNLVANAHRHGRAPVVLT FT VDGAVITVRDHGDGYPEYLLAHGPQRFRTEGGAKGHGLGLTIALGQAEVLGARLEFTNP FT PDGGALARLTLPQQP" FT misc_feature complement(95692..96246) FT /note="Pfam match to entry PF00512 signal, Signal FT carboxyl-terminal domain, score 90.80, E-value 2.8e-23" FT misc_feature complement(96286..96516) FT /note="Pfam match to entry PF00672 DUF5, Domain found in FT bacterial signal proteins, score 44.70, E-value 2.1e-09" FT CDS complement(96921..97739) FT /transl_table=11 FT /gene="SCO5305" FT /gene_synonym="SC6G9.28" FT /product="putative lipoprotein" FT /note="SC6G9.28, possible lipoprotein, len: 272 aa; unknown FT function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Contains appropriately positioned PS00013 Prokaryotic FT membrane lipoprotein lipid attachment site" FT /db_xref="UniProtKB/TrEMBL:Q9XAF4" FT /protein_id="CAB45619.1" FT /translation="MLPSRRGRPARVPAALALLLATAATGVLAACGDTGGLESAGATPA FT AHHPARLWPGLTPASSPAYDIGEVEHAPMKGVAVPGGDIRRADPVAAVRAEIAAHPDDY FT AGAGARYHETSARMADCGADGAGDEPGGCPVLRPYYRDLTGDGRPEMTLGFRLLPDRLT FT AVRVYTVEKDRLVRIMSYEDAVSAVELAGRTVIVRSPSEVAGYEYRLQWTWDADQRAML FT LTSDEMLRTDDGGRHARRPSASPSPSVSRSAAPPSSPPAAPSASPSASAR" FT misc_feature complement(97647..97679) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(97867..98346) FT /transl_table=11 FT /gene="SCO5306" FT /gene_synonym="SC6G9.27" FT /product="putative protein phosphatase" FT /note="SC6G9.27, possible protein phosphatase, len: 159 aa; FT very weak similarity to eukaryotic tyrosine and FT dual-specificity protein phosphatases e.g. TR:O70275 FT (EMBL:AF035645) Mus musculus protein tyrosine phosphatase FT 4A3 (173 aa), fasta scores; opt: 130 z-score: 173.4 E(): FT 0.025, 33.3% identity in 78 aa overlap. Alternative start FT codons are present at codons 12 and 17. Contains Pfam match FT to entry PF00782 DSPc, Dual specificity phosphatase, FT catalytic domain" FT /db_xref="GOA:Q9XAF5" FT /db_xref="InterPro:IPR000387" FT /db_xref="UniProtKB/TrEMBL:Q9XAF5" FT /protein_id="CAB45618.1" FT /translation="MPAPDRPWDEIVPGLWMGGHEFRPTPGRLEFAVVRDEFDLVQTLL FT RLPGHGPDEGVEHHVWPIPDGPLDGTQLAGVIRLARAADEALDGGRKVLVRCYHGYNRS FT GLVVAHTLMRRGSGAEEAIRLVRARRSPWALHNELFVAYLRTGLATVRLLEEPAE" FT misc_feature complement(97912..98328) FT /note="Pfam match to entry PF00782 DSPc, Dual specificity FT phosphatase, catalytic domain, score -10.00, E-value FT 0.0075" FT CDS 98460..99284 FT /transl_table=11 FT /gene="SCO5307" FT /gene_synonym="SC6G9.26c" FT /product="hypothetical protein" FT /note="SC6G9.26c, hypothetical protein, len: 274 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Alternative start codons are present at codons 8 and 14" FT /db_xref="UniProtKB/TrEMBL:Q9XAF6" FT /protein_id="CAB45617.1" FT /translation="MDGGGDGMDGLRVVPTRRHGRERLYVCLPDGGNVAWYDREEARVS FT LLSDDRRAEVLQALAPFVTGPVTVGPPPVPTPAELARLTLHPDDDLAPNRPGEALLVAL FT ERAPGPAHRLRPDPRRRALAAEQATGTALDRLDGAGLHTLHSLPLPGGDRIHHLLIGPG FT GLFALHVLPARGQRVRVADPLVALGRRTPRPLLDRVRADADRASYALTAEVHPVLVLAG FT PAHVTVTAPPRSVRVLTDRELPDLARTGGVLKPADVEALHAMARDRATWQGV" FT CDS complement(99376..100257) FT /transl_table=11 FT /gene="SCO5308" FT /gene_synonym="SC6G9.25" FT /product="conserved hypothetical protein" FT /note="SC6G9.25, conserved hypothetical protein, len: 293 FT aa; unknown function, similar to the N-terminal ends of FT hypothetical proteins from Mycobacterium tuberculosis e.g. FT TR:P95226 (EMBL:Z86089) Mycobacterium tuberculosis FT hypothetical protein (397 aa), fasta scores; opt: 534 FT z-score: 643.4 E(): 1.7e-28, 36.6% identity in 292 aa FT overlap and to the C-terminal end of TR:O34398 FT (EMBL:Z99110) Bacillus subtilis hypothetical protein (611 FT aa) (29.8% identity in 282 aa overlap). Also similar to S. FT coelicolor hypothetical protein SC4C6.19 (341 aa) (34.6% FT identity in 295 aa overlap) and (EMBL:AL033505), SC1E6.07, FT S.coelicolor hypothetical protein (319 aa) (32.8% identity FT in 259 aa overlap). Alternative start codons are present at FT codons 4, 7, 12 and 20" FT /db_xref="GOA:Q9XAF7" FT /db_xref="InterPro:IPR014145" FT /db_xref="UniProtKB/TrEMBL:Q9XAF7" FT /protein_id="CAB45616.1" FT /translation="MAPMTEVEGRRVALSNLDKVLYPAAGLTKGELLHYYATTAEVLLP FT HLRDRAVSFLRYPDGPDGQVFFTKNVPPGTPDWVTTAEVPRSEGPARMVLVQDLASLMW FT AANLVTEFHTHQWTVDDPGEADRLVFDLDPGPPATVVQCCEVALWLRERLAADGIEAYA FT KTSGAKGLHLLAGVRGASSERVSEYAKGLAVEAERALPELVVHRMTRSLRPGKVFVDWS FT QNAARKTTAAPYTVRARGVPAVSTPVTWEEVAGCGRAERFVFLTPDVGRRVRDHGDLLA FT PLFDRRRAAALP" FT CDS 100304..101401 FT /transl_table=11 FT /gene="SCO5309" FT /gene_synonym="SC6G9.24c" FT /product="conserved hypothetical protein" FT /note="SC6G9.24c, conserved hypothetical protein, len: 365 FT aa; unknown function, similar to hypothetical proteins from FT Mycobacterium tuberculosis, Bacillus subtilis and FT Archaeoglobus fulgidus e.g. TR:O05866 (EMBL:Z95209) FT Mycobacterium tuberculosis hypothetical protein (273 aa), FT fasta scores; opt: 648 z-score: 651.9 E(): 5.6e-29, 36.5% FT identity in 274 aa overlap. An alternative start codon is FT present as codon 4" FT /db_xref="GOA:Q9XAF8" FT /db_xref="InterPro:IPR009187" FT /db_xref="UniProtKB/TrEMBL:Q9XAF8" FT /protein_id="CAB45615.1" FT /translation="MLHVRSIWNGAISFGLVSIPIKLVNATESHSVSFRQIHTEDGGRI FT RYRKVCELEDREVTQAEIGKAYEDADGSMIPITDEDLSQLPIPTARTIEIVAFVPEDRI FT DPLQMGSAYYLAASGAPAAKPYTLLREALKRSNRVAIAKFALRGRERLGMLRVVGDAIA FT MHGLLWPDEVRAPEGVAPEGGVTVRDQELDLADALMDTLGEIDLDDLHDEYREAVEEVV FT AAKASGEKPPEAREEAAPGKVLDLMAALESSVRAARESRDGEGAGPAEEAEVRSLSRRK FT TSSRAPKETGGKKSTSTAAKKTAAKRAEPKKSTAKAAGSAKKTAAGSPAKGTAKKATAR FT STARSGDKGAAKSTAKKTASRRRSA" FT CDS complement(101424..101987) FT /transl_table=11 FT /gene="SCO5310" FT /gene_synonym="SC6G9.23" FT /product="hypothetical protein" FT /note="SC6G9.23, hypothetical protein, len: 187 aa; unknown FT function, probable CDS suggested by GC frameplot, FT positional base preference, amino acid composition and the FT presence of a possible RBS" FT /db_xref="UniProtKB/TrEMBL:Q9XAF9" FT /protein_id="CAB45614.1" FT /translation="MTASGPGGGDTPDGPDDAPVVPEYVWRLFLEDDERAIHASAPREP FT AARDRIPGRTRPEPPADCSGHPGRAHDTVGEPWRREDAWAGPAWRELDGRARLRRTGRV FT LGTAAAVALAVTAWSQLTTGPATPGGGPAETIGQRLEESPALPSPASVADTPASAESAG FT ASPAAFEPAPSAIPRAPASTRTFG" FT RBS complement(101997..102002) FT /note="possible RBS" FT CDS complement(102276..103022) FT /transl_table=11 FT /gene="SCO5311" FT /gene_synonym="SC6G9.22" FT /product="putative secreted protein" FT /note="SC6G9.22, possible secreted protein, len: 248 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Contains possible N-terminal signal sequence" FT /db_xref="UniProtKB/TrEMBL:Q9XAG0" FT /protein_id="CAB45613.1" FT /translation="MRLSRSRIGVVVLFGAMTLTLTALAFPAVLGLDKADGNQNRVVAS FT TKFGPLTEADRDFVVKVRAAGLWEYPLGEMVMERGTTKAMKTAGEHLVVGHAGLDAMCR FT EISPELGITLPNRASPQQEGFVAAVDAESGREFDSSAVNIMRVTHGQIFPAIAKIRAST FT KNTLVRQLADLANDTVLDHITVLEKTGLVEYDDVTFKQTGPAKLPREKVTPPPPQPGER FT VLVLKPRPDLNVNTASPTPAPSPAAP" FT RBS complement(103027..103031) FT /note="possible RBS" FT CDS complement(103186..103620) FT /transl_table=11 FT /gene="SCO5312" FT /gene_synonym="SC6G9.21" FT /product="conserved hypothetical protein" FT /note="SC6G9.21, conserved hypothetical protein, len: 144 FT aa; unknown function, similar to hypothetical proteins from FT Mycobacterium tuberculosis e.g. TR:O06553 (EMBL:Z95584) FT Mycobacterium tuberculosis hypothetical protein (147 aa), FT fasta scores; opt: 478 z-score: 561.4 E(): 6.1e-24, 55.7% FT identity in 140 aa overlap" FT /db_xref="GOA:Q9XAG1" FT /db_xref="InterPro:IPR011576" FT /db_xref="UniProtKB/TrEMBL:Q9XAG1" FT /protein_id="CAB45612.1" FT /translation="MTTTPRFDPRVLLAESRLGVLATIKSDGRPQLSPVMPAYDPEAGV FT IRVSTREGLAKTANLRRDPRAALEVTAPDGRSWATAEGVATLTGPGADPHGPEVEALVE FT YYRAAAGEHPDWDEYRSTMVSDRRVLLTITVERVYGADIG" FT CDS complement(103647..104558) FT /transl_table=11 FT /gene="SCO5313" FT /gene_synonym="SC6G9.20" FT /product="possible membrane protein" FT /note="SC6G9.20, possible membrane protein, len: 303 aa; FT unknown function, C-terminal half shows weak similarity to FT the corresponding region of TR:O05859 (EMBL:Z95120) FT Mycobacterium tuberculosis hypothetical protein (285 aa), FT fasta scores; opt: 285 z-score: 275.6 E(): 5e-08, 31.4% FT identity in 277 aa overlap. Contains a hydrophobic, FT possible membrane-spanning region near the N-terminus. FT Contains PS00142 Neutral zinc metallopeptidases, FT zinc-binding region signature" FT /db_xref="GOA:Q9XAG2" FT /db_xref="InterPro:IPR006026" FT /db_xref="UniProtKB/TrEMBL:Q9XAG2" FT /protein_id="CAB45611.1" FT /translation="MGRSTARRADRRTGPDGSGHRSRARRRSRRGPARAVLACLALGAV FT LLTAGAAVAYWRETRPPVTDDQVADVTDALDATTRTPSASPSPSASPSPKASASPSASP FT SSSPSATTIAIPATGPGTFVTARADGTTVGTGSRVRRYKVLVEKGIDVRPSAAAAEISE FT VLADRRGWTQDGTNSFRLVSSGSYDFVVKIATPGTVDRICGAAGLLTRGEVNCSVGTDV FT VVNLKRWVLGSPEFDGPIHEYRALIVNHEVGHRIGHGHETCPGAGRPAPAMMQQIKGLK FT GCVANAWPYDEKGDYLGGPAVS" FT misc_feature complement(103791..103820) FT /note="PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature" FT RBS complement(104568..104571) FT /note="possible RBS" FT misc_feature complement(104782..110534) FT /note="sequence corresponding to EMBL:X55942, S. coelicolor FT whiE locus DNA" FT CDS complement(104803..105138) FT /transl_table=11 FT /gene="SCO5314" FT /gene_synonym="SC6G9.19" FT /product="whiE protein VII" FT /note="SC6G9.19, whiE ORF VII, len: 111 aa; unknown FT function, whiE locus protein previously sequenced from S. FT coelicolor as SW:YW12_STRCO (EMBL:X55942)" FT /db_xref="GOA:P23159" FT /db_xref="InterPro:IPR006765" FT /db_xref="UniProtKB/Swiss-Prot:P23159" FT /protein_id="CAB45610.1" FT /translation="MHHTLIVARMAPGAAPDIAKVFAESDSGELPHLVGVNRRSLFEFG FT DGVYLHLIESDEDPAPTIGRLTGHPEFRQVSERLEPYVSAYDPATWRGPKDAMARCFYR FT WERTPAG" FT CDS complement(105172..105651) FT /transl_table=11 FT /gene="SCO5315" FT /gene_synonym="SC6G9.18" FT /product="polyketide cyclase" FT /note="SC6G9.18, polyketide cyclase, len: 159 aa; whiE FT locus polyketide cyclase previously sequenced from S. FT coelicolor as SW:CYPC_STRCO (EMBL:X55942)" FT /db_xref="InterPro:IPR005031" FT /db_xref="PDB:2KF2" FT /db_xref="UniProtKB/Swiss-Prot:P23154" FT /protein_id="CAB45609.1" FT /translation="MAGHTDNEITIAAPMELVWNMTNDIEKWPGLFSEYASVEVLGRDD FT DKVTFRLTMHPDADGKVWSWVSERVADPVTRTVRAQRVETGPFQYMNIVWEYAETAEGT FT VMRWTQDFAMKPDAPVDDAWMTDNINRNSRTQMALIRDRIEQAAGERRTASVLAD" FT CDS complement(105653..105925) FT /transl_table=11 FT /gene="SCO5316" FT /gene_synonym="SC6G9.17" FT /product="acyl carrier protein" FT /note="SC6G9.17, acyl carrier protein, len 90 aa; whiE FT locus acyl carrier protein previously sequenced from FT S.coelicolor as SW:ACP_STRCO (EMBL:X55942). Contains Pfam FT match to entry PF00550 pp-binding, Phosphopantetheine FT attachment site and PS00012 Phosphopantetheine attachment FT site" FT /db_xref="GOA:P23153" FT /db_xref="HSSP:2AF8" FT /db_xref="InterPro:IPR006162" FT /db_xref="UniProtKB/Swiss-Prot:P23153" FT /protein_id="CAB45608.1" FT /translation="MTDQQLDYQVTVEELSALMKRTAGVHVDPVTLRQQADDGFDTFGL FT DSLGLLGIVAELEKRYGLGLPEQAERCKTPADFLALVNGALKTGV" FT misc_feature complement(105680..105889) FT /note="Pfam match to entry PF00550 pp-binding, FT Phosphopantetheine attachment site, score 44.90, E-value FT 8.6e-11" FT misc_feature complement(105755..105802) FT /note="PS00012 Phosphopantetheine attachment site" FT CDS complement(105995..107269) FT /transl_table=11 FT /gene="SCO5317" FT /gene_synonym="SC6G9.16" FT /product="polyketide beta-ketoacyl synthase beta" FT /note="SC6G9.16, polyketide beta-ketoacyl synthase beta, FT len: 424 aa; whiE locus polyketide beta-ketoacyl synthase FT beta previously sequenced from S. coelicolor as FT SW:KAS2_STRCO (EMBL:X55942). May form heterodimer with FT SW:KAS1_STRCO, SC6G9.15 in beta-ketoacyl synthase FT beta-ketoacyl synthase alpha. Similar to others from FT S.coelicolor e.g. TR:O54149 (EMBL:AL021409) probable FT 3-oxoacyl-[acyl-carrier-protein] synthase (407 aa) (34.6% FT identity in 405 aa overlap). Contains Pfam match to entry FT PF00109 ketoacyl-synt, Beta-ketoacyl synthase" FT /db_xref="GOA:P23156" FT /db_xref="HSSP:1E5M" FT /db_xref="InterPro:IPR016038" FT /db_xref="UniProtKB/Swiss-Prot:P23156" FT /protein_id="CAB45607.1" FT /translation="MSGPQRTGTGGGSRRAVVTGLGVLSPHGTGVEAHWKAVADGTSSL FT GPVTREGCAHLPLRVAGEVHGFDAAETVEDRFLVQTDRFTHFALSATQHALADARFGRA FT DVDSPYSVGVVTAAGSGGGEFGQRELQNLWGHGSRHVGPYQSIAWFYAASTGQVSIRND FT FKGPCGVVAADEAGGLDALAHAALAVRNGTDTVVCGATEAPLAPYSIVCQLGYPELSRA FT TEPDRAYRPFTEAACGFAPAEGGAVLVVEEEAAARERGADVRATVAGHAATFTGAGRWA FT ESREGLARAIQGALAEAGCRPEEVDVVFADALGVPEADRAEALALADALGPHAARVPVT FT APKTGTGRAYCAAPVLDVATAVLAMEHGLIPPTPHVLDVCHDLDLVTGRARPAEPRTAL FT VLARGLMGSNSALVLRRGAVPPEGR" FT misc_feature complement(106019..107224) FT /note="Pfam match to entry PF00109 ketoacyl-synt, FT Beta-ketoacyl synthase, score -20.00, E-value 4.9e-11" FT CDS complement(107266..108537) FT /transl_table=11 FT /gene="SCO5318" FT /gene_synonym="SC6G9.15" FT /product="polyketide beta-ketoacyl synthase alpha" FT /note="SC6G9.15, polyketide beta-ketoacyl synthase alpha, FT len: 423 aa; whiE locus polyketide beta-ketoacyl synthase FT alpha previously sequenced from S. coelicolor as FT SW:KAS1_STRCO (EMBL:X55942). May form heterodimer with FT SW:KAS2_STRCO, SC6G9.16 beta-ketoacyl synthase beta. FT Similar to others from S.coelicolor e.g. TR:O54149 FT (EMBL:AL021409) probable 3-oxoacyl-[acyl-carrier-protein] FT synthase (407 aa) (39.1% identity in 419 aa overlap). FT Contains Pfam match to entry PF00109 ketoacyl-synt, FT Beta-ketoacyl synthase and PS00606 Beta-ketoacyl synthases FT active site" FT /db_xref="GOA:P23155" FT /db_xref="HSSP:1E5M" FT /db_xref="InterPro:IPR016038" FT /db_xref="UniProtKB/Swiss-Prot:P23155" FT /protein_id="CAB45606.1" FT /translation="MTRRRVAVTGIGVVAPGGIGTPQFWRLLSEGRTATRRISLFDPSG FT LRSQIAAECDFEPSDHGLGLATAQRCDRYVQFALVAASEAVRDANLDMNREDPWRAGAT FT LGTAVGGTTRLEHDYVLVSERGSRWDVDDRRSEPHLERAFTPATLSSAVAEEFGVRGPV FT QTVSTGCTSGLDAVGYAYHAVAEGRVDVCLAGAADSPISPITMACFDAIKATSPNNDDP FT AHASRPFDADRNGFVMGEGAAVLVLEDLEHARARGADVYCEVSGYATFGNAYHMTGLTK FT EGLEMARAIDTALDMAELDGSAIDYVNAHGSGTQQNDRHETAAVKRSLGEHAYATPMSS FT IKSMVGHSLGAIGSIELAACVLAMAHQVVPPTANYTTPDPECDLDYVPREARERTLRHV FT LSVGSGFGGFQSAVVLSGSEGGLR" FT misc_feature complement(107281..108522) FT /note="Pfam match to entry PF00109 ketoacyl-synt, FT Beta-ketoacyl synthase, score 589.00, E-value 2.8e-173" FT misc_feature complement(108007..108057) FT /note="PS00606 Beta-ketoacyl synthases active site" FT CDS complement(108534..109007) FT /transl_table=11 FT /gene="SCO5319" FT /gene_synonym="SC6G9.14" FT /product="whiE protein II" FT /note="SC6G9.14, whiE ORF II, len: 157 aa; unknown FT function, whiE locus protein previously sequenced from S. FT coelicolor as SW:WH16_STRCO (EMBL:X55942)" FT /db_xref="InterPro:IPR014710" FT /db_xref="UniProtKB/Swiss-Prot:P23157" FT /protein_id="CAB45605.1" FT /translation="MTDQQVRIVSLGDIAPNRRRGGDLRALLTPTTAGSTSGFMGVAIV FT QPGDRIAEHYHPYSEEFVYVTEGALEVDLDGVPHSLGTGQGLLIPQDMRHRFRNAGDVE FT ARLVFHLGPLAPRPELGHVDTEDAEGNALPCDGAHAGHAAGHERPAPAAEVVS" FT CDS complement(109154..110347) FT /transl_table=11 FT /gene="SCO5320" FT /gene_synonym="SC6G9.13" FT /product="whiE protein I" FT /note="SC6G9.13, whiE ORF I, len: 397 aa; unknown function, FT whiE locus protein previously sequenced from S. coelicolor FT as SW:WH42_STRCO (EMBL:X55942)" FT /db_xref="GOA:P23158" FT /db_xref="InterPro:IPR007575" FT /db_xref="UniProtKB/Swiss-Prot:P23158" FT /protein_id="CAB45604.1" FT /translation="MTVSPVVATDAPSTDATRTTATSATSPAVATDAGGVSISAFDGSR FT VRVVLMLDVHDGMQQEFLDAYERIRDRVAAVPGHVSDQLCQSLENPTQWLLTSEWESAA FT PFLAWVNSDEHLDTVEPLATCVRDTHSLRYSVLRETDGGRPAPGEPRSAPRIGDNVVRH FT ALTFTVRPGTEAETARLLSEYVSPDAHVDGSTRLLRTSLFMSGNRIVRAVEVRGDLQTA FT LRHVARQPGVRAVEEALNPYLEQDRDLGDPQSARRFFTRAAMPAVHHATYPDRSGARRE FT RLALLYPVRDGAGPDLARLLARQDAAAARNPDGPVLAATVFHRDDLVVRLVDVDGDPED FT APAEVLGLHGRGAADAERLLDAAAVGVDGSPAEAATLSRLLRRIRMTPLTDRRSAGS" FT misc_feature 110540..111457 FT /note="sequence corresponding to EMBL:X74213, S.coelicolor FT gene for aromatic hydroxylase" FT RBS 110679..110683 FT /note="possible RBS" FT CDS 110691..112574 FT /transl_table=11 FT /gene="SCO5321" FT /gene_synonym="SC6G9.12c" FT /product="polyketide hydroxylase" FT /note="SC6G9.12c, polyketide hydroxylase, len: 627 aa; FT previously partially sequenced from S.coelicolor as FT SW:HYDL_STRCO (EMBL:X74213). Highly similar to FT SW:HYDL_STRHA (EMBL:L05390), schC, Streptomyces halstedii FT putative polyketide hydroxylase involved in synthesis of a FT polyketide spore pigment (555 aa), fasta scores; opt: 2290 FT z-score: 1755.0 E(): 0, 69.2% identity in 629 aa overlap. FT Also similar to many hydroxylases of substitued aromatic FT compounds. A notable difference between this sequence and FT its Streptomyces halstedii homologue is the presence of 12x FT GGP repeats starting at aa 413. Weakly similar to TR:O50491 FT (EMBL:AL020958) S.coelicolor possible monooxygenase (541 FT aa) (29.2% identity in 583 aa overlap). This feature is FT also absent from the other related hydroxylases. Contains FT Pfam match to entry PF01360 Monooxygenase, Monooxygenase. FT Contains possible hydrophobic membrane spanning region" FT /db_xref="GOA:P42534" FT /db_xref="InterPro:IPR003042" FT /db_xref="UniProtKB/Swiss-Prot:P42534" FT /protein_id="CAB45603.1" FT /translation="MNERADRSGGAAPGGDRTHRVPVLVVGGSLVGLSTSVFLGRLGVR FT HTLVERHAGTSIHPRGRGNNVRTMEIFRVAGTEPDIRRAAATLADNHGILQAPTLAGDA FT GEWLFKQIDPGGGLARFSPSSWCLCSQNDLEPELLTHATNLGGDLRFGTELLSFEADTE FT GVTAIVKSRETGEHTTIRADYLVAADGPRSPVREQLGIGQSGPGDLFHNVSITFRSRRL FT ADVVGDRRFIVCYLTDENADGALLPVDNRENWVFHAPWHPEQGETVEDFTDERCAAHIR FT RAIGDPDLDVEITGKAPWHAAQRVARSYRSGRVLLAGDSAHEMSPTGAFGSNTGIQDAH FT NLAWKLAAVLEGWAGEALLDTYDTERRPVAEATSARAAHRSVEHSHPGFAPPPVAGGGG FT PGAGTPGGAGRGTGGPGGPGGPGGLGGPGGPGGTGGPGGPGGPGGPDGPRGAGGAPGGG FT PGGGPGGGGPQRGILNVALGYRYPRGAVVGADPATPVVPEGLDLTGAPGSRAPHLWVRR FT GQDRLSTLDLYEDSLVLLSDAAQPTGWHEAAAGVAAGMRVPLKSYRVGGSPGADLNPDD FT EETDWARAHGVTRGGAVLVRPDGFVAWRSPGPAPDPESMLRQVVGTVLARS" FT misc_feature 111231..111824 FT /note="Pfam match to entry PF01360 Monooxygenase, FT Monooxygenase, score 233.10, E-value 3.9e-66" FT repeat_region 111927..112034 FT /note="repeat 2; 12x degenerate 12 bp repeats" FT CDS 112651..113520 FT /transl_table=11 FT /gene="SCO5322" FT /gene_synonym="SC6G9.11c" FT /product="conserved hypothetical protein" FT /note="SC6G9.11c, conserved hypothetical protein, len: 289 FT aa; unknown function, similar to TR:O53410 (EMBL:AL021897) FT Mycobacterium tuberculosis hypothetical protein (285 aa), FT fasta scores; opt: 556 z-score: 639.1 E(): 2.9e-28, 38.8% FT identity in 286 aa overlap" FT /db_xref="GOA:Q9XAG3" FT /db_xref="InterPro:IPR001969" FT /db_xref="UniProtKB/TrEMBL:Q9XAG3" FT /protein_id="CAB45602.1" FT /translation="MVPVTGGVTDVADTALVLGGGGLTAYGWQIGVLAGLADAGVDLAD FT ADVLAGTSAGSLLALDLARGAAPAGLYKEQLDRERPMLDVDFTFGMTVRYLWAALGSRD FT PETVVRRLGRLALSVRDVPQSAVFAAIGAQLPVRDWPDRTVRMFAVDALTGEPTAFDAD FT SGVDLLHAMSATCALPPLFPPISIGAGRWMDGGVRSTTNADLVDDCARVVVLAPIPKGA FT GASPSARTQAETLASRGARVALLTPDRAARRAFGRNALDASRIPGAAREGRRQGAAHAG FT RIGEIWQG" FT CDS complement(113578..114072) FT /transl_table=11 FT /gene="SCO5323" FT /gene_synonym="SC6G9.10" FT /product="putative Asn-C family transcriptional regulator" FT /note="SC6G9.10, probable Asn-C family transcriptional FT regulator, len: 164 aa; similar to many e.g. TR:P94329 FT (EMBL:U85623), Lrp, Bradyrhizobium japonicum FT leucine-responsive regulatory protein (153 aa), fasta FT scores; opt: 211 z-score: 261.3 E(): 3.2e-07, 30.8% FT identity in 143 aa overlap. Similar to others from FT S.coelicolor e.g. (EMBL:AL049628), SCE94.12c, LrpA, FT probable AsnC-family transcriptional regulator (150 aa) FT (28.0% identity in 150 aa overlap). Contains probable FT helix-turn-helix motif at aa 24-45 (Score 1012, +2.63 SD). FT Contains Pfam match to entry PF01037 ASNC_trans_reg, AsnC FT family" FT /db_xref="GOA:Q9XAG4" FT /db_xref="InterPro:IPR019888" FT /db_xref="UniProtKB/TrEMBL:Q9XAG4" FT /protein_id="CAB45601.1" FT /translation="MARQGLDQLDGRMLRLLRERPREGLLEIARRLGVARGTLQARLDR FT LTGSGVVTGYGPDMDVAALGHVVQAFTTFEVDQPAREAIAARLRAVPQILEAHVVTGPG FT DIWCRIAGTSNQHVQEVIDQVLEVPGVRRSTTVIALSAVVPYRVQPLVDEVSGLSEPRL FT G" FT misc_feature complement(113686..113985) FT /note="Pfam match to entry PF01037 ASNC_trans_reg, AsnC FT family, score 29.60, E-value 1.8e-06" FT RBS 114195..114200 FT /note="possible RBS" FT CDS 114207..114887 FT /transl_table=11 FT /gene="SCO5324" FT /gene_synonym="SC6G9.09c" FT /product="putative oxidoreductase" FT /note="SC6G9.09c, possible oxidoreductase, len: 226 aa; FT weak similarity to SW:NOX_THETH (EMBL:X60110) Thermus FT aquaticus NADH dehydrogenase (205 aa), fasta scores; opt: FT 159 z-score: 201.0 E(): 0.00073, 26.7% identity in 191 aa FT overlap. Similar to TR:O75989 (EMBL:AL031010) Homo sapiens FT hypothetical protein (184 aa) (40.0% identity in 185 aa FT overlap) and to part of SW:YKH5_CAEEL (EMBL:L23649) FT Caenorhabditis elegans hypothetical protein (359 aa) (28.6% FT identity in 185 aa overlap). Weak similarity to FT SW:NOX_THETH (EMBL:X60110) Thermus aquaticus NADH FT dehydrogenase (205 aa) (26.7% identity in 191 aa overlap). FT Contains Pfam match to entry PF00881 Nitroreductase, FT Nitroreductase family" FT /db_xref="GOA:Q9XAG5" FT /db_xref="InterPro:IPR000415" FT /db_xref="UniProtKB/TrEMBL:Q9XAG5" FT /protein_id="CAB45600.1" FT /translation="MRQHTHPFVPYRPDRYDEAEMIRRGRDFVSFVDRRRSVRFFSDEP FT VPRECLDLAVAAANTAPSGAHFQPWKFAVIGDAATKHRIRVAAEEEERVNYEGGRIPPE FT WRAALARLETDSDKGFLDVVPWIVVCFAEKSTALPDGSLRKNYYVNESVGIACGLFITA FT LHAMGLSTLTHTPNPMAFLTRICARPGNERPYILFPVGYAAPDCEVPDLARKPLAEAIT FT EPPR" FT misc_feature 114285..114773 FT /note="Pfam match to entry PF00881 Nitroreductase, FT Nitroreductase family, score 20.60, E-value 0.00026" FT CDS 115103..115423 FT /transl_table=11 FT /gene="SCO5325" FT /gene_synonym="SC6G9.08c" FT /product="hypothetical protein" FT /note="SC6G9.08c, hypothetical protein, len: 106 aa; FT unknown function, improbable CD suggested by GC frameplot. FT C-terminus is proline-rich and overlaps with hypothetical FT CDS on opposite strand" FT /db_xref="UniProtKB/TrEMBL:Q9XAG6" FT /protein_id="CAB45599.1" FT /translation="MEITLAALQGRWTTLVIRELLRGDHSYSDLRAALAAPSDKVTKVA FT ADVITRWSSARARASQPVTARSRRTALASPPPSRTRAPPGTAGDRLTSPRPRRVRARPR FT RH" FT CDS complement(115374..115628) FT /transl_table=11 FT /gene="SCO5326" FT /gene_synonym="SC6G9.07" FT /product="hypothetical protein" FT /note="SC6G9.07, hypothetical protein, len: 54 aa; unknown FT function, possible CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Similar to part of (EMBL:AL049573), SCE39.23, S.coelicolor FT hypothetical protein (88 aa), fasta scores; opt: 165 FT z-score: 222.7 E(): 4.4e-05, 46.7% identity in 60 aa FT overlap. C-terminus overlaps with hypothetical CDS on FT opposite strand" FT /db_xref="UniProtKB/TrEMBL:Q9XAG7" FT /protein_id="CAB45598.1" FT /translation="MGPDRSGLVAHRSFGRMDSSSEPTGKYSITMPRDIAEAAKARSGP FT SGLSAYVAAAAARQIERDNLSELISVAEAEHGPVSDEET" FT misc_feature complement(115601..126100) FT /note="region of low %G+C content (average 61%)" FT repeat_region 115664..115685 FT /note="degenerate 22 bp inverted repeat (6 mismatches)" FT repeat_region 115664..116538 FT /note="repeat 1; insertion element IS1651, 875 bp imperfect FT inverted repeat" FT CDS 115786..116529 FT /transl_table=11 FT /gene="SCO5327" FT /gene_synonym="SC6G9.06c" FT /product="putative transposase" FT /note="SC6G9.06c, possible transposase, len: 247 aa; FT similar to TR:Q48342 (EMBL:M28508) Streptomyces lividans FT ORFA from insertion element IS493 (254 aa), fasta scores; FT opt: 585 z-score: 725.3 E(): 4.5e-33, 45.0% identity in 220 FT aa overlap. Contains probable helix-turn-helix motif at aa FT 49-70 (Score 1540, +4.43 SD)" FT /db_xref="GOA:Q9XAG8" FT /db_xref="InterPro:IPR002559" FT /db_xref="UniProtKB/TrEMBL:Q9XAG8" FT /protein_id="CAB45597.1" FT /translation="MHPAALDLPHALVEWATMLIVTREGDRRCKLRPSQRAMVALVYLR FT EHTTLAKIAAGFGISESTAHAYTRAVVDLLAACAPGLLKTLRDHEPDFVLLDGTLAECD FT RVGDGRADYSHKHRRHGVNVQVVTDPGGRLLWLSPALPGRTHDLTAARTHRIIRICERQ FT GVPIVADLAYQGAGPWLTTGIKRKPLQELTPTDKTRNRALAAARAPVERGVARLKSWRI FT FRRSRCSPNRMTSIAKAVLTLELHR" FT repeat_region complement(116517..116538) FT /note="degenerate 22 bp inverted repeat (6 mismatches)" FT tRNA complement(116658..116727) FT /note="tRNA Pseudo anticodon CCG, Cove score 20.64" FT repeat_region 116867..116892 FT /note="degenerate 26 bp inverted repeat (8 mismatches)" FT repeat_region complement(116867..117741) FT /note="repeat 1; insertion element IS1651, 875 bp imperfect FT inverted repeat" FT CDS complement(116879..117623) FT /pseudo FT /transl_table=11 FT /gene="SCO5328" FT /gene_synonym="SC6G9.05" FT /product="putative transposase pseudogene" FT /note="SC6G9.05, possible transposase pseudogene, len: 745 FT bp; similar to TR:Q48342 (EMBL:M28508) Streptomyces FT lividans ORFA from insertion element IS493 (254 aa)" FT repeat_region complement(117716..117741) FT /note="degenerate 26 bp inverted repeat (8 mismatches)" FT CDS 117823..119520 FT /transl_table=11 FT /gene="SCO5329" FT /gene_synonym="SC6G9.04c" FT /product="hypothetical protein" FT /note="SC6G9.04c, hypothetical protein, len: 565 aa; FT similar to TR:O34810 (EMBL:AE000641) Helicobacter pylori FT hypothetical protein (578 aa), fasta scores; opt: 391 FT z-score: 464.1 E(): 1.6e-18, 23.6% identity in 525 aa FT overlap and to several other hypothetical proteins from the FT same organism, with the highest similarity toward the FT N-terminus. The coding sequence has unusually low %G+C FT content" FT /db_xref="InterPro:IPR004919" FT /db_xref="UniProtKB/TrEMBL:Q9XAG9" FT /protein_id="CAB45595.1" FT /translation="MSMIYEPAKKTVGDLLGDVAKKTSVPDYQRDYSWTESHVDYFWQD FT VLGFMREQNEKTLADAEYFIGSMVRVDKAERYELLDGQQRLATIVILLSAIRDRLRPLN FT TKAYIKTQGRWIAEEDDLTGESKYSLTLSTYDRDYFRRRIQNDPVETLKPATASQTLID FT AARRKFDAELTSELDKQPDEKGREQWLLLLRDVIMNHVTTVTVTCASEQDAASIFETLN FT DRGLGLSTVDLLRNFVLRRAGEPDRDEIVSIWADVLRESNSVDVDEFLRHYWISRHGDI FT KSQRLYRAIRKYMEDSGESSLEFMRDLGSAHAAYVRLMRPDFANDATNEELQNIADLKA FT KMLYPFLLSGLTRDEEGFLSLVRAGIVFYVREGIVVKRNSSQMEKVVFSAARLMSEGGA FT TDKALALLHNGASADPVFDAAVRELRNLDTSAARYLLREIEISLRNGEETDVARPPKIH FT IEHIYPQKPKAGERWSNHTDYVGKIGNLTLLARRINTAIKNSEFAVKRLELAKSEIFLT FT REVAAHGMWDAAAIDQRQDELGKKVKSLWGWPPDVIEAVNKFPTHVEA" FT RBS 119974..119977 FT /note="possible RBS" FT CDS 119983..120885 FT /transl_table=11 FT /gene="SCO5330" FT /gene_synonym="SC6G9.03c" FT /product="hypothetical protein SC6G9.03c" FT /note="SC6G9.03c, hypothetical protein, len: 300 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition" FT /db_xref="UniProtKB/TrEMBL:Q9XAH0" FT /protein_id="CAB45594.1" FT /translation="MPKTAHIYVPSPSRENLEIGLDQGLWGWRRSALDRAGTRQAVQSL FT TEGDFLVLGHRGPNSRVAPGGWANATLQRVIVTQVSRPYFTDSTPVWPGDDYPERIGID FT VLEEEQNVPGTALGTDAMEALRLSANKQGAAVLQPGIAAVAQLADVLPLVPVLPGDATV FT DHEGTDSAVAQVLVRREQVKLRKNLLGGATEAACALCGRVLPTRFIRAAHIKRRSAASR FT QERLMMANIMPACLIGCDELFEHGYLYVTDNGTIAVSPKSNATPDLAVAAKALEGRTVA FT DYGPHRAPFYIWHRTHIAN" FT CDS complement(121048..124650) FT /transl_table=11 FT /gene="SCO5331" FT /gene_synonym="SC6G9.02" FT /product="putative DNA methylase" FT /note="SC6G9.02, possible DNA methylase, len: 1200 aa; FT highly similar to TR:O86561 (EMBL:AL031350) (71.5% identity FT in 867 aa overlap) and TR:O86674 (EMBL:AL031371) (90.8% FT identity in 370 aa overlap) which together constitute a FT single hypothetical protein split across the join between FT S.coelicolor cosmids 1F2 and 4G2. It has very weak FT similarity to DNA methylases, which combined with the FT presence of a DNA methylases signature and possible FT DNA-binding region (helix-turn-helix) provides FT circumstantial evidence of DNA-methylase function. The FT central third of the CDS is relatively AT rich. Contains FT probable helix-turn-helix motif at aa 38-59 (Score 1036, FT +2.72 SD). Contains PS00092 N-6 Adenine-specific DNA FT methylases signature" FT /db_xref="GOA:Q9XAH1" FT /db_xref="InterPro:IPR002052" FT /db_xref="UniProtKB/TrEMBL:Q9XAH1" FT /protein_id="CAB45593.1" FT /translation="MIDRKALLDHLKQQVKAVEADLGKQVKPLGEAGARLRTEYDQARK FT LGRTAATWNSWLDERVTQVAVAWVLGTVFVRFCEDNRLIPEPYLTGPDGDRRELAEARY FT DAYVESDDDPTYRGWLEKAFDELGQGQAGRLLFDKRHNPLYQIPLSHDGARELVEFWRQ FT RDEAGVLVHDFTDPLNEDGTEGWDTRFLGDLYQDLSEAARKTYALLQTPEFVEEFILDR FT TMNPAVREFGYEELKMIDPTCGSGHFVLGAFRRLVRLWAEGQPGRDVHERVRAALHSIH FT GVDINPFAVAIARFRLLVAAIAASGVRTLAEAAKYEWPIHLAVGDSLIKARQLELTLGG FT DEDGGYDPLASFTYATEDVHEHPGILQQGRYHVVVGNPPYITVKDKKLNELYRELYDAC FT GGTYALSVPFAQRFFELAKRGGDEGRAYGMVGQITANSFMKREFGTKLIERYFRDRVEL FT TEVIDTSGAYIPGHGTPTVILVGKRCKGSQRLSTIRTVRSIQGEPAAPANGKDGLVWNA FT IVDQIDKPGSVSQWVSVDDLERGRYFAKQPWILANGGLEMVEQLSKSAIKIIGSLSDAI FT GRTTHTGMDDCFYMKASAAKTLALSDSCVPVVPGDGIRDFGINSRLSTYFPYDSRGNPR FT EITLPEYRFLWPNRTVLRRRLDFGQTPTERGLRWFDHSMFFPKRYSTPLGIAFPFVATH FT SHFSLDRGGKVFNRTAPVIKLQEGASEEEHLQLLGLLNSSTAGFWLKQVSHDKGIRGEG FT GGFTSDDWERFFEFTGTKLQEFPLPAEHPTTLATTLDALAQQLSAISPEAVAVEAAPVA FT SALREAKVRWESIRARMIALQEELDWQVYSLYNLHSEDLRVSEDPDDPNIPELALGERA FT FEIVLARRVAAGEASDEWFKRHNSTPNTEVPAHWPASYREVVQKRIDAIESNRAIGMVE FT RPEYKRRWATEGWDALQEKALRSWLLDHMEDRDLWFDENGQPTILTLARLTDALSRDED FT FVSVAKLYAPRQDMHKVVAELITDEHVPFLSALRYKPSGLKKHADWEEVWDLQRKEDAA FT PDEPAKRKIRDSIPVPPKYASADFLRPSYWRARGKLDVPKERFISYGQTNAATPELYGW FT AGWDHKEQAQALATYFTNTALTTEEITPFLAGLLELQPWLYQWHNGFDMLYSGPPADFF FT ASYRQQKQAEHGLTDDHLRAWRPSASTRGKDKKR" FT misc_feature complement(123511..123531) FT /note="PS00092 N-6 Adenine-specific DNA methylases FT signature" FT CDS 124873..126384 FT /transl_table=11 FT /gene="SCO5332" FT /gene_synonym="SCBAC5H2.01" FT /gene_synonym="SC6G9.01c" FT /product="hypothetical protein" FT /note="SCBAC5H2.01, unknown (fragment), len: >33 aa" FT /note="SC6G9.01c, hypothetical protein, partial CDS, len: FT >409 aa; unknown function, possible CDS suggested by FT positional base preference and amino acid composition. The FT coding sequence has unusually low %G+C content. Alternative FT start codons are present at codons 9 and 27" FT /db_xref="UniProtKB/TrEMBL:Q8CJR7" FT /protein_id="CAD55350.1" FT /translation="MFRNPGGFVRVSEYYGIGRSQGALDFVDVDITDDVPVYIDPGMIR FT HLPDDWGKECLLMLTTFFDSVLDAVRKNDKKRARYLLGHLGEPNETHLGFSAGRSAGRG FT FGKQMGVTLAEKLAASQAAQTGLIEDLEDTAFFIEKVGKDIVSDITTNIIRGPLIAYTQ FT QMATVFGIPMEEGVASGAAWNPHSQDWEHGYVRLPIAGDRKLLLVPKVIVRRDLHMSRS FT EYYRNHLVPALQSEELDKPSSRLVRTLKDGSRRVWVGDIKAHYGSTKPDVTRESLLRPD FT IYANYREIKRKSAPPPISHGELSEISNTPLPDYEKLLTDVLQTPAGKDSAGEYHRRIEA FT LLSAVFYPSLVMPELEEELHAGRKRVDISYTNVAQSGFFAFLGKHKIKSTYVMVECKNY FT GKEVGNPELDQLSSRFSPLRGQFGILACRSFEDKDRFLKRCRDTALDYRGFVIALDDDD FT LRELVADVLEAVNWIPADPPPAEPEVQPRVENYPLLFRRFKALVN" FT misc_feature 126001..127478 FT /note="low G+C region (58.79%)" FT CDS complement(126470..127375) FT /transl_table=11 FT /gene="SCO5333" FT /gene_synonym="SCBAC5H2.02c" FT /product="conserved hypothetical protein" FT /note="SCBAC5H2.02c, conserved hypothetical protein, len: FT 301 aa; similar to TR:Q9RU61 (EMBL:AE001997) Deinococcus FT radiodurans conserved hypothetical protein DR1533, 299 aa; FT fasta scores: opt: 496 z-score: 583.0 E(): 6.7e-25; 46.3% FT identity in 298 aa overlap. Contains Pfam match to entry FT PF02182 G9a, Domain of unknown function" FT /db_xref="InterPro:IPR003105" FT /db_xref="UniProtKB/TrEMBL:Q9ADD4" FT /protein_id="CAC33897.1" FT /translation="MIGEIPGVAAGQPYNSRRLAHEAGVHRPLQAGICGTKATGAESIV FT VSGGYKDDEDYGDVIIYTGHGGRDSAGNQVSDQSLDDSGNAALVTSYLRGLPVRVIRGS FT QSGSPFAPSNGYRYDGLYRVASYTSKLGIDGFLIWQFRMEAYEETPTPKITKVRALFAE FT PTDCAKQDPVAASGTEQPERVTSMVQRIVRSSAIADTVKAWHQDQCQTCGIHIEVPGGF FT YSEGAHIQALGRPHNGPDRTDNMLCLCPNCHVMLDAGAIVLSDDLIVSKNGQLVGPLRT FT HPKHKVNIECVRRHRERWRQ" FT misc_feature complement(126929..127375) FT /note="Pfam match to entry PF02182 G9a, Domain of unknown FT function, score 144.00, E-value 2.6e-39" FT stem_loop complement(127465..127616) FT /note="possible stem loop. Score 125: 55/65 (84%) matches, FT 0 gaps" FT CDS complement(127894..128208) FT /transl_table=11 FT /gene="SCO5334" FT /gene_synonym="SCBAC5H2.03c" FT /product="hypothetical protein SCBAC5H2.03c" FT /note="SCBAC5H2.03c, unknown, len: 104 aa. Highly FT hydrophilic. High content in arginine and serine amino acid FT residues" FT /db_xref="UniProtKB/TrEMBL:Q9ADD3" FT /protein_id="CAC33898.1" FT /translation="MGDQAYQARRRSQRFKVPSTVEGMEPGVTQSGRVADVMQPRSSNE FT KIPVSLGHSRGNLASPSSHGLSMQPAIPERRKQGLSEFRRSLGRVQCRRHGWNGSRVQR FT " FT RBS complement(128211..128214) FT CDS 128221..128484 FT /transl_table=11 FT /gene="SCO5335" FT /gene_synonym="SCBAC5H2.04" FT /product="hypothetical protein SCBAC5H2.04" FT /note="SCBAC5H2.04, unknown, len: 87 aa" FT /db_xref="UniProtKB/TrEMBL:Q9ADD2" FT /protein_id="CAC33899.1" FT /translation="MYEAEQRGLSTELAVYEREDSPVLDALIFADMTTGPAGQSFDFDT FT RIDEILVRYEPGSEVHNAISKARPYLQGAVERTRDRMAHQPM" FT CDS complement(128472..128942) FT /transl_table=11 FT /gene="SCO5336" FT /gene_synonym="SCBAC5H2.05c" FT /product="putative mutT-like protein" FT /note="SCBAC5H2.05c, possible mutT-like protein, len: 156 FT aa; similar to plasmid borne SW:MUTT_STRAM (EMBL:Z19590) FT Streptomyces ambofaciens plasmid pSAM2 mutT-like protein FT ORF154, 154 aa; fasta scores: opt: 182 z-score: 232.1 E(): FT 2.4e-05; 32.7% identity in 153 aa overlap. Contains Pfam FT match to entry PF00293 mutT, MutT-like domain, and match to FT Prosite entry PS00893 mutT domain signature" FT /db_xref="GOA:Q9ADD1" FT /db_xref="HSSP:1NQZ" FT /db_xref="InterPro:IPR020084" FT /db_xref="UniProtKB/TrEMBL:Q9ADD1" FT /protein_id="CAC33900.1" FT /translation="MARVDYFNDPNAPKANSLVPSVTAVARNEAGEVLLIHKTDNDLWA FT LPGGGIDLGESAPDAAVRETKEETGFDVEVTGLVGIYTNPGHVMAYDDGEVRQQFSICY FT HARITGGELRTSSESKEVAFVDPSKLDELNIHPSMRMRIEHGLTDRAEPYIG" FT misc_feature complement(128496..128891) FT /note="Pfam match to entry PF00293 mutT, MutT-like domain, FT score 97.10, E-value 3.5e-25" FT misc_feature complement(128739..128798) FT /note="PS00893 mutT domain signature" FT CDS complement(128971..129702) FT /transl_table=11 FT /gene="SCO5337" FT /gene_synonym="SCBAC5H2.06c" FT /product="hypothetical protein SCBAC5H2.06c" FT /note="SCBAC5H2.06c, unknown, len: 243 aa" FT /db_xref="GOA:Q9ADD0" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q9ADD0" FT /protein_id="CAC33901.1" FT /translation="MANERLRAAISAKGETIQSVAEHIGVDPKSVERWITTSRTPHRGH FT RWKAASFLGVDEVYLWPSVEKQAEKASTSELITYYPHRGAVPAPLWSSLIEKATDQVDI FT LVYAGLFLFDSHPDLPDQLAEKAKAGAQIRILLGDPDSEAVRQRGEEEGIGGDLAARAR FT ITRRYLEPAMSTLGVEVRLHDTILYNSIYRFDEDVLVNPHVLGAPAGQNPVMHFRYLPG FT ARTFRHYMRSFDYAWERGREA" FT RBS complement(129709..129713) FT RBS 129847..129851 FT CDS 129860..130213 FT /transl_table=11 FT /gene="SCO5338" FT /gene_synonym="pra2" FT /gene_synonym="SCBAC5H2.07" FT /product="putative regulatory protein" FT /note="SCBAC5H2.07, pra2, probable regulatory protein, len: FT 117 aa; highly similar to plasmid borne TR:Q53733 FT (EMBL:Z34987) Streptomyces ambofaciens pSAM2 regulatory FT protein Pra, 116 aa; fasta scores: opt: 535 z-score: 695.9 FT E(): 3.5e-31; 72.9% identity in 118 aa overlap and to FT TR:Q9X8D1 (EMBL:AL049573) Streptomyces coelicolor Pra, FT regulatory protein SCE39.08c, 118 aa; fasta scores: opt: FT 565 z-score: 733.8 E(): 0; 76.3% identity in 118 aa FT overlap" FT /db_xref="InterPro:IPR001412" FT /db_xref="UniProtKB/TrEMBL:Q9ADC9" FT /protein_id="CAC33902.1" FT /translation="MRQIPVDTSNATVMVAKAPQPKVKDRRTGEIATDKDGVTLMVVEV FT MFSTPDEVEILKLTVPQPGVSEDLTMGTPVALTGLVASAWENEFNGQKKHGIAFRAVAV FT TSLAAGASSSKAA" FT misc_feature 130046..130081 FT /note="PS00178 Aminoacyl-transfer RNA synthetases class-I FT signature" FT CDS 130217..131572 FT /transl_table=11 FT /gene="SCO5339" FT /gene_synonym="traSA2" FT /gene_synonym="SCBAC5H2.08" FT /product="putative plasmid transfer protein" FT /note="SCBAC5H2.08, traSA2, probable plasmid transfer FT protein, len: 451 aa; highly similar to TR:Q9X8D0 FT (EMBL:AL049573) Streptomyces coelicolor plasmid transfer FT protein TraSA, 451 aa; fasta scores: opt: 2539 z-score: FT 2830.9 E(): 0; 84.3% identity in 451 aa overlap, to plasmid FT borne SW:TRSA_STRAM (EMBL:Z19593) Streptomyces ambofaciens FT transfer protein TraSA, 415 aa; fasta scores: opt: 2345 FT z-score: 2615.4 E(): 0; 84.8% identity in 415 aa overlap FT and to TR:O86766 (EMBL:AL031035) Streptomyces coelicolor FT traSA:integrase fusion protein SC6A9.34, 768 aa; fasta FT scores: opt: 2326 z-score: 2253.5 E(): 0; 85.4% identity in FT 405 aa overlap. Contains Pfam match to entry PF01580 FT FtsK_SpoIIIE, FtsK/SpoIIIE family and match to Prosite FT entry PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9ADC8" FT /db_xref="InterPro:IPR002543" FT /db_xref="UniProtKB/TrEMBL:Q9ADC8" FT /protein_id="CAC33903.1" FT /translation="MTWLIVALVLVVAAAGLLRWRRPAWYWLTFGVTLAALRVLVRYGS FT VMDACGLTVPAPRWRLTLARMTNRPVPGPRAPRILRFRVTRTGLVLRLKLRPGQDAFDV FT AASCDRLRHSFAMYGVTSRELRSGVVELRMTGYDVLKRVQMPALAETRPMRVPVALRED FT GAVHYRDYRAVPHGLVIGATESGKSVYQRNLVAALAPQRVALVGIDCKQGVELFPLARR FT FSALADNPDTAAELLDALVSHMQDVYQLIRAEQRITADVPDAEIAADIWDLPENLRPVP FT IVVLVDEVAELALFATKDDEKRRDRIITALARLAQLGRAAGIYLEICGQRFGSELGKGI FT TMLRAQLTGRTAHRVNDEASANMAFGDIAPDAVLAAISIPTDTPGVAITGDSAGGWARI FT RAPHTTLRQAVNVCNRHADLTPDLPALAPFRPALGTLAPVPAPAVESAPAAA" FT misc_feature 130631..131218 FT /note="Pfam match to entry PF01580 FtsK_SpoIIIE, FT FtsK/SpoIIIE family, score 210.00, E-value 3.7e-59" FT misc_feature 130757..130780 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 131582..131587 FT CDS 131593..131790 FT /transl_table=11 FT /gene="SCO5340" FT /gene_synonym="SCBAC5H2.09" FT /product="hypothetical protein SCBAC5H2.09" FT /note="SCBAC5H2.09, unknown, len: 65 aa" FT /db_xref="UniProtKB/TrEMBL:Q9ADC7" FT /protein_id="CAC33904.1" FT /translation="MATAKKPTTRRKITPPAPEPALCPDCDGKGETRETVRVGARKMRV FT TDDHQTALCLTCWGTGHATD" FT RBS 131796..131805 FT CDS 131812..132480 FT /transl_table=11 FT /gene="SCO5341" FT /gene_synonym="spdA2" FT /gene_synonym="SCBAC5H2.10" FT /product="SpdA2 protein" FT /note="SCBAC5H2.10, spdA2 protein, len: 222 aa; highly FT similar to plasmid borne TR:Q07193 (EMBL:Z19593) FT Streptomyces ambofaciens probably involved in pSAM2 FT spreading (intramycelial transfer) SpdA protein, 224 aa; FT fasta scores: opt: 1086 z-score: 974.5 E(): 0; 74.9% FT identity in 223 aa overlap and to TR:Q9X8C9 (EMBL:AL049573) FT Streptomyces coelicolor SpdA protein, 217 aa; fasta scores: FT opt: 1079 z-score: 968.6 E(): 0; 75.5% identity in 220 aa FT overlap. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9ADC6" FT /protein_id="CAC33905.1" FT /translation="MRTVLRPDAVLVQAVIAGALSFAHLHDLAAAAGQDGWKAWAYPIS FT VDLLFVAAWRRLRTDGPSRLSWCWFLIALAASLGANIATAGLLDLSDVPAWLRILVAGW FT PALAFLGGTLLAHSPTGHAPDPDPAPEVEREPEPVPESDPEPAAVPAPQETPALPVAEP FT APVPASPPAVPVPAALVDHARKVAADHEHRTGSRIDTDTLRARLGVPPHLADAIAAQLT FT " FT RBS 132484..132491 FT CDS 132502..132693 FT /transl_table=11 FT /gene="SCO5342" FT /gene_synonym="spdB2" FT /gene_synonym="SCBAC5H2.11" FT /product="SpdB2 protein" FT /note="SCBAC5H2.11, spdB2 protein, len: 63 aa; highly FT similar to plasmid borne TR:Q07194 (EMBL:Z19593) FT Streptomyces ambofaciens probably involved in pSAM2 FT spreading (intramycelial transfer) SpdB protein, 58 aa; FT fasta scores: opt: 354 z-score: 518.8 E(): 2.5e-21; 82.3% FT identity in 62 aa overlap and to TR:Q9X8C8 (EMBL:AL049573) FT Streptomyces coelicolor SpdB protein, 53 aa; fasta scores: FT opt: 350 z-score: 513.7 E(): 4.9e-21; 90.4% identity in 52 FT aa overlap" FT /db_xref="InterPro:IPR007806" FT /db_xref="UniProtKB/TrEMBL:Q9ADC5" FT /protein_id="CAC33906.1" FT /translation="MPARDFFHSVMRIGPVQIGTHRDRHGQTKHAAVCSNDGCGWSADY FT TSQSAAQLAARTHRCKIR" FT RBS 132692..132697 FT CDS 132704..132859 FT /transl_table=11 FT /gene="SCO5343" FT /gene_synonym="spdC2" FT /gene_synonym="SCBAC5H2.12" FT /product="SpdC2 protein" FT /note="SCBAC5H2.12, spdC2 protein, len: 51 aa; identical to FT plasmid borne TR:Q07195 (EMBL:AJ005260) Streptomyces FT ambofaciens probably involved in pSAM2 spreading FT (intramycelial transfer) SpdC, 51 aa and highly similar to FT TR:Q9X8C7 (EMBL:AL049573) Streptomyces coelicolor SpdC FT protein, 51 aa; fasta scores: opt: 280 z-score: 413.2 E(): FT 1.9e-15; 78.4% identity in 51 aa overlap. Contains possible FT hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q7AKG3" FT /protein_id="CAC33907.1" FT /translation="MDVPLWFALLCVGVLGVKLIRPPWWLIAVLLLGGYLLADSLLAPV FT IDTAVK" FT RBS 132858..132863 FT CDS 132872..133195 FT /transl_table=11 FT /gene="SCO5344" FT /gene_synonym="spdD2" FT /gene_synonym="SCBAC5H2.13" FT /product="SpdD2 protein" FT /note="SCBAC5H2.13, spdD2 protein, len: 107 aa; highly FT similar to plasmid borne TR:Q07196 (EMBL:AJ005260) FT Streptomyces ambofaciens probably involved in pSAM2 FT spreading (intramycelial transfer) SpdD protein, 104 aa; FT fasta scores: opt: 517 z-score: 454.5 E(): 9.7e-18; 74.5% FT identity in 106 aa overlap and to TR:Q9X8C6 (EMBL:AL049573) FT Streptomyces coelicolor SpdD protein, 105 aa; fasta scores: FT opt: 485 z-score: 428.0 E(): 2.9e-16; 70.6% identity in 109 FT aa overlap. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9ADC4" FT /protein_id="CAC33908.1" FT /translation="MLRPKLPTMPQPTSTVTPPAVIEPTTITPGTPPPTPTAPAPAPVS FT ARPTMQLTPGTALALVGGGTAVVLVVGAVLVSMLLAVAITAASVAVCAVVLRSLLASDA FT KRR" FT CDS 133285..133836 FT /transl_table=11 FT /gene="SCO5345" FT /gene_synonym="SCBAC5H2.14" FT /product="conserved hypothetical protein" FT /note="SCBAC5H2.14, conserved hypothetical protein, len: FT 183 aa; highly similar to plasmid borne TR:CAA06454 FT (EMBL:AJ005260) Streptomyces ambofaciens unknown ORF183, FT 183 aa; fasta scores: opt: 1018 z-score: 1225.2 E(): 0; FT 81.4% identity in 183 aa overlap. Contains Pfam match to FT entry PF00990 DUF9, Domain of unknown function DUF9 and a FT TTA leucine codon, possible target for bldA regulation" FT /db_xref="InterPro:IPR000160" FT /db_xref="UniProtKB/TrEMBL:Q9ADC3" FT /protein_id="CAC33909.1" FT /translation="MDLQIAAALVPLLGWAVHGSILTHRLVSARRDPLTGLHTRAGWTA FT RAEHCIRRHPDAAVLLLDLDHFKTLNDTHGHAAGDAALVATADRLRTWCGRHGTAGRLG FT GDEFVAVVQDLTAADLDALIAALHRPLHYAGRSLPLAASVGVCRLAELPMPLLTDALAA FT ADAAMYAAKGRSRRGSRLSR" FT misc_feature 133318..133320 FT /gene="none" FT /note="TTA leucine codon. Possible target for bldA FT regulation" FT misc_feature 133348..133818 FT /note="Pfam match to entry PF00990 DUF9, Domain of unknown FT function DUF9, score 168.10, E-value 1.5e-46" FT RBS 133906..133912 FT CDS 133922..134107 FT /transl_table=11 FT /gene="SCO5346" FT /gene_synonym="SCBAC5H2.15" FT /product="hypothetical protein SCBAC5H2.15" FT /note="SCBAC5H2.15, unknown, len: 61 aa" FT /db_xref="UniProtKB/TrEMBL:Q9ADC2" FT /protein_id="CAC33910.1" FT /translation="MAQHTPPAPRICPACDGFATVAVTLGGRDPRGHLRTLTTDCPACH FT GTGTAPAHRVREGARA" FT RBS 134089..134093 FT CDS 134100..135464 FT /transl_table=11 FT /gene="SCO5347" FT /gene_synonym="repSA2" FT /gene_synonym="SCBAC5H2.16" FT /product="replication initiation protein" FT /note="SCBAC5H2.16, repSA2, replication initiation protein, FT len: 454 aa; highly similar to plasmid borne SW:REPS_STRAM FT (EMBL:Z19594) Streptomyces ambofaciens replication FT initiation protein repSA, 459 aa; fasta scores: opt: 2806 FT z-score: 3256.0 E(): 0; 90.8% identity in 446 aa overlap FT and to TR:Q9X8C5 (EMBL:AL049573) Streptomyces coelicolor FT replication initiation protein repSA, 466 aa; fasta scores: FT opt: 2759 z-score: 3201.4 E(): 0; 88.1% identity in 453 aa FT overlap" FT /db_xref="UniProtKB/TrEMBL:Q9ADC1" FT /protein_id="CAC33911.1" FT /translation="MPDTLLDPTTLGDLLRVASAPDYTRWEDQIRRTGGCADPIHLTGW FT TLHKDKTTGATLHHYTTADEPGGRLRLACGNRRASRCPACAWTYAGDTYHLIRAGLAGD FT DRRDIPATVRDHPRVFATLTAPSFGPVHNRPDRGTCRCGTHHAPDAPELGTALDPDTYD FT YAGAVLFNNHAGQLWQRFTNRLRREVAARAGLTQRELKECARLSYGKVAEFQKRGAVHF FT HAVIRLDGPDGPDTPPPVWATVDLLTDAIRAAAGHSYTSVSVPAADGQPARTFRWGTQL FT DVRPVKAFGDGSDITEQAVASYVAKYATKAAENTGTLDRRIGELAELDRHGVPDHTRRL FT IEACKTLDSLYPDRRLWAWAHMLGFRGHFSSKSRRYSTTLGALRQARADYRAAQGHAAL FT GIDDAEPDTVLVLADWQYAGHGHTPGESVLAATIARDLQLNRQTAREELAALEGA" FT RBS 135454..135459 FT CDS 135466..135651 FT /transl_table=11 FT /gene="SCO5348" FT /gene_synonym="SCBAC5H2.17" FT /product="putative excisionase" FT /note="SCBAC5H2.17, possible excisionase, len: 61 aa; FT similar to TR:Q53965 (EMBL:X71358) Streptomyces coelicolor FT plasmid SLP1 DNA for xis and int genes, Xis, 61 aa; fasta FT scores: opt: 148 z-score: 233.1 E(): 2.1e-05; 38.3% FT identity in 60 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9ADC0" FT /protein_id="CAC33912.1" FT /translation="MKDELMTVPQILDELGGVSRRTFYRWRELGQGPAAFKLPNGELRV FT WRSDFRTWLRQLEAAA" FT RBS 135636..135640 FT CDS 135648..137021 FT /transl_table=11 FT /gene="SCO5349" FT /gene_synonym="SCBAC5H2.18" FT /product="putative integrase" FT /note="SCBAC5H2.18, probable integrase, len: 457 aa; FT similar to TR:CAC08268 (EMBL:AL392146) Streptomyces FT coelicolor integrase Int, 455 aa; fasta scores: opt: 1486 FT z-score: 1774.0 E(): 0; 50.3% identity in 455 aa overlap FT and to plasmid borne TR:Q53966 (EMBL:X71358) Streptomyces FT coelicolor plasmid SLP1 DNA for xis and int genes, Int, 455 FT aa; fasta scores: opt: 1486 z-score: 1774.0 E(): 0; 50.3% FT identity in 455 aa overlap" FT /db_xref="GOA:Q9ADB9" FT /db_xref="InterPro:IPR002104" FT /db_xref="UniProtKB/TrEMBL:Q9ADB9" FT /protein_id="CAC33913.1" FT /translation="MKSLDVKVWGVRKRNTKKSSYDVRWTVAGNVFSEQFRTKGLADHY FT RSKLLRAAHGGEEFDTVTGLPDSMVEKAASMSWYAFALRYLAMKWPHAAPNTRNGINES FT LTAVTMTLLDDRPGRPPEELIRRALRNWAFVLPGPDDRELPDEIAHALHWVSKASRPLA FT DLGDAAIARAVLDALKLKLDGTAAAAETVRRKRRTLVNALHYAVDLGEFKENPITGIRW FT KKPKVAGEVDPRVVANPEQARSLLTAVSYVGGYGRARGRRLVGLFACMYYGAFRPAEAV FT GLTAADLKLPETGWGTALLNRTRPSAGKQWTDSGETHDDRGLKNRPAEEVRLVPIPPQL FT VAILRRHLDTFGTAEDGRLFTNERGGVVGSSTYYRVWQEARAFALLPAAVASPLAARPY FT DLRHSALSTWLNAGVDPTEVAARAGNSVEVLLSRYAKCIDGRQEVVNRKIEELLREYE" FT CDS 137053..137598 FT /transl_table=11 FT /gene="SCO5350" FT /gene_synonym="SCBAC5H2.19" FT /product="hypothetical protein SCBAC5H2.19" FT /note="SCBAC5H2.19, unknown, len: 181 aa. Contains two TTA FT leucine codons, possible targets for bldA regulation" FT /db_xref="UniProtKB/TrEMBL:Q9ADB8" FT /protein_id="CAC33914.1" FT /translation="MDWGLRYISAACRRSLVVGCTCRVAFGLAGGLLPQRFRPVRALRL FT GCRTGDPHGMGLLEREPRRLSGGQSRCPDCGLLQDRVPTLEQDWVLLEPDMNPLAHTVP FT AEHRWIELSDGRVTVYEVCPPDQSQRCRVEHRLACPARPLPDLWPWLTSLRGENARRVE FT RQNDPEPPPPPEEWPDAG" FT misc_feature 137224..137226 FT /gene="none" FT /note="TTA leucine codon, possible target for bldA FT regulation" FT misc_feature 137284..137286 FT /gene="none" FT /note="TTA leucine codon, possible target for bldA FT regulation" FT tRNA complement(137771..137845) FT /note="tRNA Arg anticodon CCG, Cove score 77.44" FT CDS 138025..138528 FT /transl_table=11 FT /gene="SCO5351" FT /gene_synonym="SCBAC5H2.20" FT /product="putative regulatory protein" FT /note="SCBAC5H2.20, possible regulatory protein, len: 167 FT aa; similar to the N-terminal domain of several regulatory FT proteins, e.g. TR:Q9X6C1 (EMBL:AF135389) Tolypothrix FT PCC7601 DNA binding response regulator RpaA, 247 aa; fasta FT scores: opt: 332 z-score: 343.7 E(): 1.4e-11; 42.0% FT identity in 119 aa overlap. Contains Pfam match to entry FT PF00072 response_reg, Response regulator receiver domain" FT /db_xref="GOA:Q9ADB7" FT /db_xref="HSSP:1D4Z" FT /db_xref="InterPro:IPR001789" FT /db_xref="UniProtKB/TrEMBL:Q9ADB7" FT /protein_id="CAC33915.1" FT /translation="MPRPSGRILVVDDNKVIRQLIRVNLELEGFEVVTAGDGAECLEVV FT QQVRPDAVTLDVVMPRLDGLRTAARLRADPRTRDLPIAIVSACTQYEVDAGSAAGADAF FT LSKPFEPAELVGLVRQLVERKGSGSTVVRGASGAGPGQPGPGAGASPPRVRGLAGESGA FT SAQA" FT misc_feature 138040..138378 FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 115.90, E-value 7.5e-31" FT CDS 138650..139693 FT /transl_table=11 FT /gene="SCO5352" FT /gene_synonym="SCBAC5H2.21" FT /product="putative arginyl tRNA synthetase" FT /note="SCBAC5H2.21, possible arginyl tRNA synthetase, len: FT 347 aa; similar to SW:SYR_BRELA (EMBL:Z21501) FT Brevibacterium lactofermentum arginyl tRNA synthetase (EC FT 6.1.1.19) ArgS, 550 aa; fasta scores (to C-terminal FT region): opt: 234 z-score: 260.2 E(): 6.4e-07; 36.0% FT identity in 161 aa overlap and blastp scores (to N-terminal FT region): Score = 182 (64.1 bits), Expect = 1.2e-28, Sum FT P(2) = 1.2e-28; Identities = 45/116 (38%), Positives = FT 65/116 (56%) and similar to SW:SYR_MYCTU (EMBL:Z73419) FT Mycobacterium tuberculosis arginyl t-RNA synthetase (EC FT 6.1.1.19) ArgS or MTCY373.12, 550 aa; fasta scores: opt: FT 216 z-score: 240.5 E(): 8.1e-06; 28.1% identity in 363 aa FT overlap" FT /db_xref="GOA:Q9ADB6" FT /db_xref="InterPro:IPR008909" FT /db_xref="UniProtKB/TrEMBL:Q9ADB6" FT /protein_id="CAC33916.1" FT /translation="MTPVELSRTVLHAVRRAVDAGELSVAVPTRAVVAPPGPGGCGDYA FT TGIALQLARPAGQPPFRVAEVLRPYLVGTDGITDVVLTGPGFLNISLDRAASDVGLVAE FT ILRRGDRYGHADQPDGRVVQLHCPHDLRAVVVAEASARLLRSQGALVRVSAEGFEDAWT FT SVLGVTVDAVGHAPAELPVNVRPVPAHGSADPMSLGRDAGRWALLHPAAGDRPRIGDEH FT LVQREGNPLFRVRYAHARARAAARNAAGLGFTAAPGPVAERDLLAALADHPRVLAAAAD FT HRAPDRLARHLVTVADAALPFLPTVLPRGGEKPSAAHRARLALAEAVGAVLAGGLALLG FT IDAPEHL" FT CDS 139712..141103 FT /transl_table=11 FT /gene="SCO5353" FT /gene_synonym="lysA" FT /gene_synonym="SCBAC5H2.22" FT /product="diaminopimelate decarboxylase" FT /note="SCBAC5H2.22, lysA, diaminopimelate decarboxylase, FT len: 463 aa; highly similar to SW:DCDA_CORGL (EMBL:X07563) FT Corynebacterium glutamicum diaminopimelate decarboxylase FT (EC 4.1.1.20) LysA, 445 aa; fasta scores: opt: 1503 FT z-score: 1722.5 E(): 0; 51.0% identity in 443 aa overlap. FT Contains Pfam match to entry PF00278 Orn_DAP_Arg_deC, FT Pyridoxal-dependent decarboxylase and matches to Prosite FT entries PS00878 Orn/DAP/Arg decarboxylases family 2 FT pyridoxal-P attachment site and PS00879 Orn/DAP/Arg FT decarboxylases family 2 signature 2" FT /db_xref="GOA:Q9ADB5" FT /db_xref="HSSP:1HKV" FT /db_xref="InterPro:IPR002986" FT /db_xref="UniProtKB/TrEMBL:Q9ADB5" FT /protein_id="CAC33917.1" FT /translation="MSRSAHPAGPRHADVLPEGHYTAPADDLNALDPKVWARTVGRDAD FT GVVTVGGIPVTQLAEEYGTPAYLLDEADFRERARAWRTAFGDDADVFYAGKAFLSRAVV FT RWLDEEGLNLDVCSGGELATALSAGMPAERIAFHGNNKSPEEIERAVRAGVGRIVLDSF FT QEIVRVAHIAQSLGKRQRVQIRITVGVEAHTHEFIATAHEDQKFGIPLAGGQAAEAVRR FT ALKLDGLEVIGIHSHIGSQIFDMSGFEVAAHRVVGLLKDIRDEHGVELPEIDLGGGLGI FT AYTSDDDPREPHEIAKALTEIVTRECEAARLATPRISVEPGRAIVGPTAFTLYEVGTVK FT PLEGLRTYVSVDGGMSDNIRTALYDAEYSVALASRTSDAEPMLVRVVGKHCESGDIVVK FT DAFLPGDLAPGDLIAVPATGAYCRSMASNYNHALRPPVVAVRDGAARVVVRRETEEDLL FT RLDVG" FT misc_feature 139910..141007 FT /note="Pfam match to entry PF00278 Orn_DAP_Arg_deC, FT Pyridoxal-dependent decarboxylase, score 400.80, E-value FT 5.1e-119" FT misc_feature 139988..140044 FT /note="PS00878 Orn/DAP/Arg decarboxylases family 2 FT pyridoxal-P attachment site" FT misc_feature 140510..140551 FT /note="PS00879 Orn/DAP/Arg decarboxylases family 2 FT signature 2" FT RBS 141254..141258 FT CDS 141265..142554 FT /transl_table=11 FT /gene="SCO5354" FT /gene_synonym="thrA" FT /gene_synonym="SCBAC5H2.23" FT /product="homoserine dehydrogenase" FT /note="SCBAC5H2.23, thrA, homoserine dehydrogenase, len: FT 429 aa; highly similar to SW:DHOM_CORGL (EMBL:Y00546) FT Corynebacterium glutamicum homoserine dehydrogenase (EC FT 1.1.1.3) Hom or ThrA, 445 aa; fasta scores: opt: 1592 FT z-score: 1742.3 E(): 0; 57.7% identity in 423 aa overlap. FT Contains Pfam matches to entries PF00742 Homoserine_dh, FT Homoserine dehydrogenase and PF01842 ACT, ACT domain and FT match to Prosite entry PS01042 Homoserine dehydrogenase FT signature. Note: Can participate in the biosynthesis of FT Methionine, Lysine and Threonine (plus following steps to FT Valine, Leucine and Isoleucine)" FT /db_xref="GOA:Q9ADB4" FT /db_xref="InterPro:IPR019811" FT /db_xref="UniProtKB/TrEMBL:Q9ADB4" FT /protein_id="CAC33918.1" FT /translation="MRTRPLKVALLGCGVVGSKVARIMTTHAADLAARIGAPVELAGVA FT VRRPDKVREGIDPALVTTDATALVKRGDIDVVVEVIGGIEPARTLITTAFAHGASVVSA FT NKALIAQDGAALHAAADEHGKDLYYEAAVAGAIPLIRPLRESLAGDKVNRVLGIVNGTT FT NFILDAMDSTGAGYQEALDEATALGYAEADPTADVEGFDAAAKAAILAGIAFHTRVRLD FT DVYREGMTEVTAADFASAKEMGCTIKLLAICERAADGGSVTARVHPAMIPLSHPLANVR FT EAYNAVFVESDAAGQLMFYGPGAGGSPTASAVLGDLVAVCRNRLGGATGPGESAYAALP FT VSPMGDVVTRYHISLDVADKPGVLAQVATVFAEHGVSIDTVRQSGKDGEASLVVVTHRA FT SDAALGGTVEALRKLDTVRGVASIMRVEGE" FT misc_feature 141313..142230 FT /note="Pfam match to entry PF00742 Homoserine_dh, FT Homoserine dehydrogenase, score 462.40, E-value 3.7e-135" FT misc_feature 141814..141882 FT /note="PS01042 Homoserine dehydrogenase signature" FT misc_feature 142315..142533 FT /note="Pfam match to entry PF01842 ACT, ACT domain, score FT 59.30, E-value 8.6e-14" FT RBS 142544..142549 FT CDS 142561..143619 FT /transl_table=11 FT /gene="SCO5355" FT /gene_synonym="thrC" FT /gene_synonym="SCBAC5H2.24" FT /product="threonine synthase" FT /note="SCBAC5H2.24, thrC, threonine synthase, len: 352 aa; FT similar to SW:THRC_BACSU (EMBL:X04603) Bacillus subtilis FT threonine synthase (EC 4.2.99.2) ThrC, 352 aa; fasta FT scores: opt: 1373 z-score: 1545.9 E(): 0; 58.7% identity in FT 344 aa overlap. Contains Pfam match to entry PF00291 PALP, FT Pyridoxal-phosphate dependent enzyme and match to Prosite FT entry PS00165 Serine/threonine dehydratases FT pyridoxal-phosphate attachment site" FT /db_xref="GOA:Q9ADB3" FT /db_xref="HSSP:1E5X" FT /db_xref="InterPro:IPR004450" FT /db_xref="UniProtKB/TrEMBL:Q9ADB3" FT /protein_id="CAC33919.1" FT /translation="MTHQWRGIIEEYRDRLPVSDSTPVVTLREGGTPLVPAQVLSERTG FT CEVHLKVEGANPTGSFKDRGMTMAISKAKEEGAQAVICASTGNTSASAAAYGVRAGMVS FT AVLVPQGKIALGKMGQALVHGAKILQVDGNFDDCLTLARALSDNYPVALVNSVNPVRIE FT GQKTAAFEIVDMLGDAPDIHVLPVGNAGNITAYWKGYQEYAADGVSTKKPRMWGFQASG FT SAPIVRGEVVKDPSTIATAIRIGNPASWDFALAARDESGGAIDEVTDREILRAYRLLAS FT QEGVFVEPASAASVAGLLKAAEQGKVDPGQRIVCTVTGNGLKDPDWAVAGAPQPVTVPV FT DAATAAERLGLV" FT misc_feature 142633..143520 FT /note="Pfam match to entry PF00291 PALP, FT Pyridoxal-phosphate dependent enzyme, score 310.50, E-value FT 2e-89" FT misc_feature 142717..142758 FT /note="PS00165 Serine/threonine dehydratases FT pyridoxal-phosphate attachment site" FT RBS 143887..143892 FT CDS 143905..144834 FT /transl_table=11 FT /gene="SCO5356" FT /gene_synonym="thrB" FT /gene_synonym="SCBAC5H2.25" FT /product="homoserine kinase" FT /note="SCBAC5H2.25, thrB, homoserine kinase, len: 309 aa; FT similar to SW:KHSE_CORGL (EMBL:Y00546) Corynebacterium FT glutamicum homoserine kinase (EC 2.7.1.39) ThrB, 308 aa; FT fasta scores: opt: 728 z-score: 820.7 E(): 0; 43.3% FT identity in 275 aa overlap. Contains Pfam match to entry FT PF00288 GHMP_kinases, GHMP kinases putative ATP-binding FT proteins and match to Prosite entry PS00627 GHMP kinases FT putative ATP-binding domain" FT /db_xref="GOA:Q9ADB2" FT /db_xref="InterPro:IPR014721" FT /db_xref="UniProtKB/Swiss-Prot:Q9ADB2" FT /protein_id="CAC33920.1" FT /translation="MAGPAFRAAAVRVRVPATSANLGPGFDALGLALGLYDDVVVRVAD FT SGLHIDIAGEGSETLPRDEKHLLVRSLRTAFDLLGGQPRGLEIVCANRIPHGRGLGSSS FT AAICAGIVAARAVTIGGEARLDDAALLDLATEIEGHPDNVAACLLGGFTLSWMESGAAR FT AIRMEPSDSIVPVVFVPGKPVLTQTARGLLPRSVPHVDAAANAGRAALLVEALTRRPEL FT LLPATEDRLHQEYRAPAMPESTALVERLRGDGIPAVISGAGPTVMALADADTADKVEAL FT AGTDWAANRLGLDQQGATVLPLATASDT" FT misc_feature 144142..144321 FT /note="Pfam match to entry PF00288 GHMP_kinases, GHMP FT kinases putative ATP-binding proteins, score 41.30, E-value FT 3.2e-10" FT misc_feature 144184..144219 FT /note="PS00627 GHMP kinases putative ATP-binding domain" FT RBS 145253..145257 FT CDS 145264..147348 FT /transl_table=11 FT /gene="SCO5357" FT /gene_synonym="rho" FT /gene_synonym="SCBAC5H2.26" FT /gene_synonym="2SC6G5.01" FT /product="transcription termination factor Rho" FT /note="SCBAC5H2.26, rho, transcription terminator factor FT (fragment), len: >344 aa; highly similar to N-terminal FT region of SW:RHO_STRLI (EMBL:X95444) Streptomyces lividans FT transcription terminator factor Rho, 707 aa; fasta scores: FT opt: 1705 z-score: 1432.0 E(): 0; 95.8% identity in 357 aa FT overlap" FT /note="2SC6G5.01, rho, transcription termination factor, FT partial CDS, len: >383aa; strongly similar to many eg. FT SW:P03002 (RHO_ECOLI) transcription termination factor Rho FT from Escherichia coli (419 aa) fasta scores; opt: 1432, FT z-score: 1584.9, E(): 0, 57.3% identity in 370 aa overlap. FT Almost identical to C-terminal portion of SW:P52157 FT (RHO_STRLI) transcription termination factor Rho from FT Streptomyces lividans (707 aa) fasta scores; opt: 2468, FT z-score: 2723.8, E(): 0, 99.7% identity in 383 aa overlap. FT Contains Pfam match to entry PF00006 ATP-synt_ab, ATP FT synthase alpha/beta family and Prosite match to PS00017 FT ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q8CJR6" FT /db_xref="HSSP:1PVO" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q8CJR6" FT /protein_id="CAD55351.1" FT /translation="MSDTTDLMGARVEETAAAPATDASAPATGAGSRRRRGTGLEGMVL FT AELQQVASGLGIRGTARMRKSQLIEVIKEAQAAGGAPAKAAPAAADTAGETKPKRRSTS FT RTRTGDEAPAEKAEKAGKADKKADKAAADKAAAQQQIEIPGQPSPKVNASAEQAAPADD FT APSERRRRRATSDAGSPSATDTTVAVETRAEPKADTSAPQQSQGHQQGQGDARSDAEGG FT DGRRRDRRDRGDRDRGDRGERGRDRRNKGDDQQNQGGGRQDRQQQGGGRQDRQQHDDGY FT DDDGSGRRGRRGRYRDRRGRRGRDEIQEPQINEDDVLIPVAGILDILDNYAFIRTSGYL FT PGPNDVYVSLAQVRKNGLRKGDHLTGAVRQPKEGERREKFNALVRLDSVNGMAPEHGRG FT RPEFNKLTPLYPQDRLRLETDPGVLTTRIIDLVAPIGKGQRGLIVAPPKTGKTMIMQAI FT ANAITHNNPECHLMVVLVDERPEEVTDMQRSVKGEVISSTFDRPAEDHTTVAELAIERA FT KRLVELGHDVVVLLDSITRLGRAYNLAAPASGRILSGGVDSTALYPPKRFFGAARNIED FT GGSLTILATALVDTGSRMDEVIFEEFKGTGNAELKLDRKLADKRIFPAVDVDASGTRKE FT EILLGSDELAITWKLRRVLHALDQQQAIELLLDKMKQTKSNAEFLMQIQKTTPTPGNGD FT " FT misc_feature 146224..147162 FT /note="Pfam match to entry PF00006 ATP-synt_ab, ATP FT synthase alpha/beta family, score -104.30, E-value 0.0002" FT misc_feature 146596..146619 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 147789..147793 FT CDS 147797..148945 FT /transl_table=11 FT /gene="SCO5358" FT /gene_synonym="2SC6G5.02" FT /product="putative membrane protein" FT /note="2SC6G5.02, possible membrane protein, len: 382 aa; FT regions similar to many of undefined function e.g. FT TR:O68907 (EMBL:AF058302) FrnA from Streptomyces FT roseofulvus (770 aa) fasta scores; opt: 747, z-score: FT 793.3, E(): 0, 40.8% identity in 304 aa overlap. Also FT similar to others from Streptomyces coelicolor e.g. FT TR:O69850 (EMBL:AL023702) putative transcriptional FT regulator (366 aa) fasta scores; opt: 1200, z-score: FT 1277.4, E(): 0, 52.2% identity in 356 aa overlap. Contains FT possible membrane-spanning hydrophobic regions" FT /db_xref="InterPro:IPR004474" FT /db_xref="UniProtKB/TrEMBL:Q9K4E6" FT /protein_id="CAB94529.1" FT /translation="MSAESTPDPAIPGPGQSRTPGPGRRGKGRRRKPTAKRRKALLVAA FT WSAAGIVVLGGTGAGVLYFKLNGNLTSVDIDQALGADRPEKADNGSENILVLGSDTRSG FT GNKKLGGGTDDGTARSDTAMIVHVYKGHKKASVVSIPRDTLIDRPDCTDTDGGEHPAAD FT GVMFNSAYSTGGAACAVKTVESISGLRMDHYLEVDFSGFQNLIDDLGGVQVTTTEDIKD FT PDSHLDLTAGTHRLDGEQALGLVRTRHGVGDGSDLGRIQLQQAFVKALVDQVKDIGLLG FT NPKKLYDVADTATKTVTTDSDLGSVNSLMSFASGLKGIGPDKMHMVTMPVVYDPADANR FT VLVEKDKAQQVWTALKNDRPIPKAATEGTATGEAKGVVNTGE" FT RBS 149060..149064 FT misc_feature 149070..149273 FT /note="Pfam match to entry PF01197 Ribosomal_L31, Ribosomal FT protein L31, score 120.60, E-value 2.9e-32" FT CDS 149070..149294 FT /transl_table=11 FT /gene="SCO5359" FT /gene_synonym="rpmE3" FT /gene_synonym="2SC6G5.03" FT /product="50S ribosomal protein L31" FT /note="2SC6G5.03, rpmE3, 50S ribosomal protein L31, len: 74 FT aa; strongly similar to many eg. SW:P02432 (RL31_ECOLI) 50S FT ribosomal protein L31 from Escherichia coli (70 aa) fasta FT scores; opt: 252, z-score: 365.9, E(): 6.6e-13, 50.7% FT identity in 73 aa overlap. Contains Pfam match to entry FT PF01197 Ribosomal_L31, Ribosomal protein L31 and Prosite FT match to PS01143 Ribosomal protein L31 signature." FT /db_xref="GOA:Q9K4E5" FT /db_xref="InterPro:IPR002150" FT /db_xref="UniProtKB/Swiss-Prot:Q9K4E5" FT /protein_id="CAB94530.1" FT /translation="MKRDIHPEYVETQVSCTCGASFTTRSTIESGTIRAEVCSECHPFY FT TGKQKILDTGGRVARFEARFGKASAGSKK" FT misc_feature 149193..149249 FT /note="PS01143 Ribosomal protein L31 signature" FT RBS 149392..149396 FT CDS 149403..150479 FT /transl_table=11 FT /gene="SCO5360" FT /gene_synonym="prfA" FT /gene_synonym="2SC6G5.04" FT /product="peptide chain release factor 1 (RF-1)" FT /note="2SC6G5.04, prfA, peptide chain release factor 1 FT (RF-1), len: 358aa; strongly similar to many eg. SW:P13654 FT (RF1_SALTY) peptide chain release factor 1 (RF-1) from FT Salmonella typhimurium (360 aa) fasta scores; opt: 804, FT z-score: 899.6, E(): 0, 46.4% identity in 358 aa overlap. FT Contains Pfam match to entry PF00472 RF-1, Peptidyl-tRNA FT hydrolase domain and Prosite match to PS00745 FT Prokaryotic-type class I peptide chain release factors FT signature." FT /db_xref="GOA:Q9K4E4" FT /db_xref="HSSP:1GQE" FT /db_xref="InterPro:IPR005139" FT /db_xref="UniProtKB/Swiss-Prot:Q9K4E4" FT /protein_id="CAB94531.1" FT /translation="MFEAVEELVAEHADLEKKLADPSVHSDQANARKLNKRYAELTPIV FT ATFRSWKQTGDDMETAREFAADDPDFAAEVKELDKQRDELTEKLRLLLVPRDPSDDKDV FT ILEIKAGAGGDESALFAGDLLRMYLRYAERIGWKTEIIDSTESELGGYKDVQVAVKTKG FT GQGATEPGQGVWARLKYEGGVHRVQRVPATESQGRIHTSAAGVLVTPEAEEIDVEINPN FT DLRIDVYRSSGPGGQSVNTTDSAVRITHIPTGVVASCQNEKSQLQNKEQAMRILRSRLL FT AAAQEEAEKEAADARRSQVRTVDRSEKIRTYNFPENRISDHRVGFKAYNLDQVLDGDLD FT SVIQACVDADSAAKLAAA" FT misc_feature 150030..150371 FT /note="Pfam match to entry PF00472 RF-1, Peptidyl-tRNA FT hydrolase domain, score 244.60, E-value 1.4e-69" FT misc_feature 150090..150140 FT /note="PS00745 Prokaryotic-type class I peptide chain FT release factors signature" FT RBS 150537..150541 FT CDS 150548..151393 FT /transl_table=11 FT /gene="SCO5361" FT /gene_synonym="2SC6G5.05" FT /product="putative methylase" FT /note="2SC6G5.05, probable methylase, len: 281aa; similar FT to many eg. TR:P72542 (EMBL:U60417) PapM from Streptomyces FT pristinaespiralis which catalyses the two successive FT N-methylation steps of 4-amino-L-phenylalanine leading to FT DMPAPA via 4-methylamino-L-phenylalanine (292 aa) fasta FT scores; opt: 723, z-score: 865.6, E(): 0, 44.5% identity FT in 265 aa overlap. Contains Prosite match to PS00092 N-6 FT Adenine-specific DNA methylases signature and a possible FT membrane-spanning hydrophobic region." FT /db_xref="GOA:Q9K4E3" FT /db_xref="HSSP:1NV8" FT /db_xref="InterPro:IPR019874" FT /db_xref="UniProtKB/TrEMBL:Q9K4E3" FT /protein_id="CAB94532.1" FT /translation="MNLLLAEVAQATQRLADAGVPSPRTDAEELAAYLHGVKRGELHTV FT PDADFDARYWEVVARREAREPLQHITGRAYFRYLELQVGPGVFVPRPETESVVGWAIDA FT VRAMDVVEPCIVDLCTGSGAIALALAQEVPRSRVHAVELSEDALKWTRRNMEGSRVDLR FT QGDALTAFPDLDGQVDLVVSNPPYIPLTEWEYVAPEARDHDPELALFSGEDGLDLIRGL FT ERTAHRLLRPGGVVVVEHADTQGGQVPWIFTEERGWADAADHPDLNNRPRFATARKALP FT " FT misc_feature 151088..151108 FT /note="PS00092 N-6 Adenine-specific DNA methylases FT signature" FT RBS 151430..151435 FT CDS 151444..152091 FT /transl_table=11 FT /gene="SCO5362" FT /gene_synonym="2SC6G5.06" FT /product="conserved hypothetical protein" FT /note="2SC6G5.06, conserved hypothetical protein, len: FT 281aa; similar to many eg. SW:Q10618 (YD01_MYCTU) FT hypothetical protein from Mycobacterium tuberculosis (217 FT aa) fasta scores; opt: 777, z-score: 892.2, E(): 0, 56.7% FT identity in 208 aa overlap. Contains Pfam match to entry FT PF01300 Sua5_yciO_yrdC, SUA5/yciO/yrdC family and Prosite FT match to PS01147 SUA5/yciO/yrdC family signature." FT /db_xref="InterPro:IPR006070" FT /db_xref="UniProtKB/TrEMBL:Q9K4E2" FT /protein_id="CAB94533.1" FT /translation="MARRYDTNDATDRVTGLREAASAVRRGELVVLPTDTVYGIGADAF FT AAEAVGDLLEAKGRGRNMPSPVLIGSPNTLHGLVTDFSEMAWELVDAFWPGALTLVAKH FT QPSLQWDLGETRGTVAVRMPLHPVAIELLTEVGPMAVSSANLTGHPAPEDCDAAQQMLG FT DSVSVYLDGGPTPGIVPSSIVDVTREVPVLLRAGALSAEELRKVVPDLEVAN" FT misc_feature 151507..152034 FT /note="Pfam match to entry PF01300 Sua5_yciO_yrdC, FT SUA5/yciO/yrdC family, score 174.80, E-value 1.4e-48" FT misc_feature 151528..151566 FT /note="PS01147 SUA5/yciO/yrdC family signature" FT RBS 152254..152258 FT CDS 152268..152768 FT /transl_table=11 FT /gene="SCO5363" FT /gene_synonym="2SC6G5.07" FT /product="hypothetical protein 2SC6G5.07" FT /note="2SC6G5.07, unknown, len: 166 aa" FT /db_xref="GOA:Q9K4E1" FT /db_xref="UniProtKB/TrEMBL:Q9K4E1" FT /protein_id="CAB94534.1" FT /translation="MLGGGLIVESAGTWGHEGAPMEANAETVLTDFGADPAGFTGRELL FT DEHVIRADLVLTATRDHRAQVISMGHSAGLRTFTLKEFTRLVNAIDPATLPPLEDGVVT FT RARALVRAAAALRGWLLAPTVEADEVYDPYGAPLPFFRSIGDEIHQALDPVVTALTGVP FT ARM" FT RBS 152846..152849 FT CDS 152856..154112 FT /transl_table=11 FT /gene="SCO5364" FT /gene_synonym="glyA3" FT /gene_synonym="2SC6G5.08" FT /product="serine hydroxymethyltransferase" FT /note="2SC6G5.08, glyA3, serine hydroxymethyltransferase FT (EC 2.1.2.1), len: 418 aa; strongly similar to many e.g. FT SW:P00477 (GLYA_ECOLI) serine hydroxymethyltransferase from FT Escherichia coli (417 aa) fasta scores; opt: 1164, z-score: FT 1265.0, E(): 0, 47.9% identity in 407 aa overlap. Contains FT Pfam match to entry PF00464 SHMT, Serine FT hydroxymethyltransferase. Also similar to two others from FT Streptomyces coelicolor; SC2A11.04c (SW:O86565 FT (GLYA_STRCO)) and SC5G8.05 (TR:CAB89056 (EMBL:AL353872))." FT /db_xref="GOA:Q9K4E0" FT /db_xref="HSSP:1DFO" FT /db_xref="InterPro:IPR001085" FT /db_xref="UniProtKB/TrEMBL:Q9K4E0" FT /protein_id="CAB94535.1" FT /translation="MSVTHEIIEADDSSVGVLLRQDPELAEILFAEGRRQSTTLQLIAA FT ENFTSPAVLAALGSPLANKYAEGYPGARHHGGCEIVDVAERLAAQRAQALFGAEHANVQ FT SHSGSSAVLAAYAALLRPGDTVLALGLPYGGHLTHGSPANFSGRWFDFVGYGVDAETGL FT IDHDQVRTLARARRPKAIVCGSIAYPRHLDYAAFRDIADEVGAYLIADAAHPIGLVAGG FT AAPSPVPYADIVCATTHKVLRGPRGGMILCGSELAERVDRAVFPFTQGGAQMHTIAAKA FT VAFGEAATPAFAAYAHQVVANARALAAHLAAEGLVVTTGGTDTHLLTADPAPLGVDGKT FT ARGLLAAAGIVLDCCALPHADARGLRLGTAAVTTQGMGEREMRAVATLVAGVLRGTTDP FT AAARADVRDLTAEFPPYPD" FT misc_feature 152907..154022 FT /note="Pfam match to entry PF00464 SHMT, Serine FT hydroxymethyltransferase, score 585.60, E-value 2e-175" FT RBS 154248..154252 FT CDS 154256..155560 FT /transl_table=11 FT /gene="SCO5365" FT /gene_synonym="2SC6G5.09" FT /product="putative transferase" FT /note="2SC6G5.09, possible transferase, len: 434 aa; FT similar to many putative transferases e.g. SW:Q10606 FT (RFE_MYCTU) putative undecaprenyl-phosphate FT alpha-N-acetylglucosaminyltransferase (EC 2.4.1.-) from FT Mycobacterium tuberculosis (404 aa); fasta scores; opt: FT 965, z-score: 1122.5, E(): 0, 43.7% identity in 375 aa FT overlap and SW:Q03521 (MRAY_BACSU) FT phospho-N-acetylmuramoyl-pentapeptide-transferase (EC FT 2.7.8.13) (324 aa) from Bacillus subtilis; fasta scores; FT opt: 252, z-score: 297.6, E(): 4.2e-09, 26.9% identity in FT 342 aa overlap. Contains Pfam match to entry PF00953 FT Glycos_transf_4, Glycosyl transferase." FT /db_xref="GOA:Q9K4D9" FT /db_xref="InterPro:IPR000715" FT /db_xref="UniProtKB/TrEMBL:Q9K4D9" FT /protein_id="CAB94536.1" FT /translation="MREYLLTLCITAAVTYLLTGPVRKFAIVAGAMPEIRARDVHREPT FT PRLGGIAMFFGLCAGLLVADHLTNLSEVFEKSNEPRALLSGAALIWLIGVLDDKFEIDA FT LIKLGGQMIAAGVMVVQGLTILWIPVPGVGTVALTQWQGTLLTVALVVITINAVNFVDG FT LDGLAAGMVCIAAAAFFMYAYRIWYSYGIEAAAPASLFAVILMGMCLGFLPHNMHPARI FT FMGDSGSMLIGLVLAAGAISVTGQVDPDLMNLFSGSERNSVHQMVPVYIPLVMPLTIIA FT IPAADLILAIVRRTWRGQSPFAADRGHLHHRLLEIGHSHSRAVLIMYFFSALIAFGALA FT YSVNAASMWIVLSVVFLSAIGLVLLLLPRFTPRAPRWAESLVPPRYRRRKAAVAEDGGA FT GDAAVEAEGEERVPVTVGVSGVNGATAVGHRTGTR" FT misc_feature 154499..154993 FT /note="Pfam match to entry PF00953 Glycos_transf_4, FT Glycosyl transferase, score 111.10, E-value 2.1e-29" FT misc_feature 155466..164045 FT /note="Region equivalent to that previously sequenced in FT Streptomyces lividans (EMBL:Z22606)." FT RBS 155811..155814 FT CDS 155823..156257 FT /transl_table=11 FT /gene="SCO5366" FT /gene_synonym="atpI" FT /gene_synonym="2SC6G5.10" FT /product="ATP synthase protein I" FT /note="2SC6G5.10, atpI, ATP synthase protein I, len: 144 FT aa; identical to SW:P50015 (ATPZ_STRLI) ATP synthase FT protein I from Streptomyces lividans (144 aa). Contains FT possible membrane-spanning hydrophobic regions" FT /db_xref="GOA:P0A302" FT /db_xref="UniProtKB/Swiss-Prot:P0A302" FT /protein_id="CAB94537.1" FT /translation="MPSNDVRILLQAAVPAAAVGAVAAVVSAVVAGGKGAVGAVVATVL FT AMLFMGIGLYVLQRTAKSLPHLFQAMGLMLYAAQILLLFVFLAAFKNTTLFNPRSFAVS FT LLVVTLAWIAAQTRAHMKAKVLYVEPEPTGEKPEKTGHSS" FT RBS 156472..156476 FT CDS 156483..157304 FT /transl_table=11 FT /gene="SCO5367" FT /gene_synonym="atpB" FT /gene_synonym="2SC6G5.11" FT /product="ATP synthase A chain" FT /note="2SC6G5.11, atpB, ATP synthase A chain (EC 3.6.1.34), FT len: 273aa; similar to many eg. SW:P15012 (ATP6_RHORU) ATP FT synthase A chain from Rhodospirillum rubrum (241 aa) fasta FT scores; opt: 356, z-score: 432.3, E(): 1.3e-16, 35.7% FT identity in 252 aa overlap. Identical to SW:P50012 FT (ATP6_STRLI) ATP synthase A chain from Streptomyces FT lividans. Contains Pfam match to entry PF00119 ATP-synt_A, FT ATP synthase A chain and Prosite match to PS00449 ATP FT synthase a subunit signature. Contains possible FT membrane-spanning hydrophobic regions." FT /db_xref="GOA:Q9K4D8" FT /db_xref="InterPro:IPR000568" FT /db_xref="UniProtKB/TrEMBL:Q9K4D8" FT /protein_id="CAB94538.1" FT /translation="MSADPTQVLAFETDCHIFDGCGFPSPGLHSFLFEPLWGDHDSNLY FT FNKPMLLALLGSIVIVGFFWAAFRKPKVVPGKLQMVAEAGYDFIRRGVVYETIGKKEGE FT KYVPLVVSLFFFVWMMNLWSIIPVAQFPVTSIIAYPAVLAAIVYVTWITLTFKRQGFVG FT FFKNVTGYDKSLGPVLPLAMLIEFFSNILIRPFTHAVRLFANMFAGHTLLLLFTIASWY FT LLNGVGIAYAGVSFIMTVVMTAFELFIQALQAYVFVLLTCTYIQGAMAEHH" FT misc_feature 156789..157283 FT /note="Pfam match to entry PF00119 ATP-synt_A, ATP synthase FT A chain, score 75.20, E-value 1.3e-18" FT misc_feature 157071..157100 FT /note="PS00449 ATP synthase a subunit signature" FT RBS 157367..157372 FT CDS 157380..157610 FT /transl_table=11 FT /gene="SCO5368" FT /gene_synonym="atpE" FT /gene_synonym="2SC6G5.12" FT /product="ATP synthase C chain" FT /note="2SC6G5.12, atpE, ATP synthase C chain (EC 3.6.1.34), FT len: 76aa; strongly similar to many eg. SW:P12409 FT (ATPL_ANASP) ATP synthase C chain from Anabaena sp. (strain FT PCC 7120) (81 aa) fasta scores; opt: 194, z-score: 262.9, FT E(): 3.6e-07, 43.8% identity in 73 aa overlap. Identical to FT SW:P50014 (ATPL_STRLI) ATP synthase C chain from FT Streptomyces lividans. Contains Pfam match to entry PF00137 FT ATP-synt_C, ATP synthase subunit C, Prosite match to FT PS00605 ATP synthase c subunit signature and possible FT membrane-spanning hydrophobic regions." FT /db_xref="GOA:P0A304" FT /db_xref="InterPro:IPR002379" FT /db_xref="UniProtKB/Swiss-Prot:P0A304" FT /protein_id="CAB94539.1" FT /translation="MSQTLAAVEGSLGSIGYGLAAIGPGVGVGIIFGNGTQAMARQPEA FT AGLIRANQILGFAFCEALALIGLVMPFVYGY" FT misc_feature 157413..157604 FT /note="Pfam match to entry PF00137 ATP-synt_C, ATP synthase FT subunit C, score 48.40, E-value 1.6e-10" FT misc_feature 157497..157562 FT /note="PS00605 ATP synthase c subunit signature" FT CDS 157652..158206 FT /transl_table=11 FT /gene="SCO5369" FT /gene_synonym="atpf" FT /gene_synonym="2SC6G5.13" FT /product="ATP synthase B chain" FT /note="2SC6G5.13, atpF, ATP synthase B chain (EC 3.6.1.34), FT len: 184aa; similar to many eg. SW:P00859 (ATPF_ECOLI) ATP FT synthase B chain from Escherichia coli (156 aa) fasta FT scores; opt: 246, z-score: 256.4, E(): 8.3e-07, 31.5% FT identity in 146 aa overlap. Almost identical to SW:P50013 FT (ATPF_STRLI) ATP synthase B chain from Streptomyces FT lividans (181 aa) fasta scores; opt: 1092, z-score: 1068.3, FT E(): 0, 97.3% identity in 184 aa overlap. Contains Pfam FT match to entry PF00430 ATP-synt_B, ATP synthase B/B', FT possible membrane-spanning hydrophobic regions and FT coiled-coil region 55-95aa. Contains possible hydrophobic FT membrane spanning region" FT /db_xref="GOA:Q9K4D7" FT /db_xref="InterPro:IPR005864" FT /db_xref="UniProtKB/Swiss-Prot:Q9K4D7" FT /protein_id="CAB94540.1" FT /translation="MSPMLQIAAEEMENPLIPPIPELVIGLIAFVIVFGFLAKKLLPNI FT NKVLEERREAIEGGIEKAEAAQTEAQSVLEQYKAQLAEARHEAARLRQEAQEQGATLIA FT EMRAEGQRQREEIIAAGHAQIQADRKAAASALRQDVGKLATELAGKLVGESLEDHARQS FT RVIDRFLDELDDKATTAEATR" FT misc_feature 157715..158179 FT /note="Pfam match to entry PF00430 ATP-synt_B, ATP synthase FT B/B' CF(0), score 108.90, E-value 7.3e-30" FT CDS 158203..159027 FT /transl_table=11 FT /gene="SCO5370" FT /gene_synonym="atpH" FT /gene_synonym="2SC6G5.14" FT /product="ATP synthase delta chain" FT /note="2SC6G5.14, atpH, ATP synthase delta chain (EC FT 3.6.1.34), len: 274aa; similar to many eg. SW:P00831 FT (ATPD_ECOLI) ATP synthase delta chain from Escherichia coli FT (177 aa) fasta scores; opt: 184, z-score: 217.1, E(): FT 0.00013, 27.0% identity in 141 aa overlap. Almost identical FT to SW:P50008 (ATPD_STRLI) ATP synthase delta chain from FT Streptomyces lividans (272 aa) fasta scores; opt: 1515, FT z-score: 1684.3, E(): 0, 93.0% identity in 271 aa overlap. FT Contains Pfam match to entry PF00213 OSCP, ATP synthase FT delta (OSCP) subunit and Prosite match to PS00389 ATP FT synthase delta (OSCP) subunit signature." FT /db_xref="GOA:Q9K4D6" FT /db_xref="InterPro:IPR000711" FT /db_xref="UniProtKB/Swiss-Prot:Q9K4D6" FT /protein_id="CAB94541.1" FT /translation="MSGMHGASREALAAARERLDALTDSTSVDAGSLADELAAVTALLH FT REVSLRRVLTDPAQSGEAKAELAQRLLGTQVSGTAVDLVAGTVRSRWSQSRDLVDALEQ FT LANIADLTAAQKRGRLDNVEDELFRFGRIISSNTELRAALTSRSATTAAKSELLAGLLG FT SRAERTTERLVTRLVTAPRGRSLESGLESLSKLAADRRDRMVAVVTSAVPLSDTQKQRL FT GAALAKVYGRPMHLNLDVDPEVLGGIRVQVGDEVINGSIADRLEDAGRRLAS" FT misc_feature 158770..159018 FT /note="Pfam match to entry PF00213 OSCP, ATP synthase delta FT (OSCP) subunit, score 49.70, E-value 1.2e-13" FT misc_feature 158902..158961 FT /note="PS00389 ATP synthase delta (OSCP) subunit signature" FT RBS 159207..159212 FT CDS 159221..160810 FT /transl_table=11 FT /gene="SCO5371" FT /gene_synonym="atpA" FT /gene_synonym="2SC6G5.15" FT /product="ATP synthase alpha chain" FT /note="2SC6G5.15, atpA, ATP synthase alpha chain, len: FT 529aa; strongly similar to many eg. SW:P37808 (ATPA_BACSU) FT ATP synthase alpha chain from Bacillus subtilis (501 aa) FT fasta scores; opt: 1900, z-score: 2061.3, E(): 0, 58.1% FT identity in 513 aa overlap. Identical to SW:P50001 FT (ATPA_STRLI) ATP synthase alpha chain from Streptomyces FT lividans. Contains Pfam match to entry PF00422 FT ATP-synt_A-c, ATP synthase Alpha chain, C terminal, Pfam FT match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta FT family, Prosite match to PS00017 ATP/GTP-binding site motif FT A (P-loop) and Prosite match to PS00152 ATP synthase alpha FT and beta subunits signature" FT /db_xref="GOA:Q9K4D5" FT /db_xref="InterPro:IPR000194" FT /db_xref="UniProtKB/Swiss-Prot:Q9K4D5" FT /protein_id="CAB94542.1" FT /translation="MAELTIRPEEIRDALENFVQSYKPDAASREEVGTVTLAGDGIAKV FT EGLPSAMANELLKFEDGTLGLALNLEEREIGCVVLGEFSGIEEGQPVSRTGEVLSVAVG FT EGYLGRVVDPLGNPIDGLGEIETSGRRALELQAPTVMQRKSVHEPMETGYKAVDAMTPI FT GRGQRQLIIGDRQTGKTALAVDTIINQRDNWRTGDPNKQVRCIYVAIGQKGSTIASVRG FT ALEENGALEYTTIVAAPASDPAGFKYLAPYTGSAIGQQWMYEGKHVLIIFDDLSKQADA FT YRAVSLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDAEGAGSMTGLPIVETKANDVSA FT FIPTNVISITDGQCFLESDLFNAGQRPALNVGISVSRVGGSAQHKAMKQVSGRLRVDLA FT QFRELEAFAAFGSDLDAASKSQLERGQRMVELLKQNQYQPMSTEDQVVSVWAGTTGKMD FT EVPVADIRRFEKELLEYLHRQEQGLMTSIREGGKMSDDTLQAVAEAIAAFKKQFETSDG FT KLLGEDAPSAAK" FT misc_feature 159311..160351 FT /note="Pfam match to entry PF00006 ATP-synt_ab, ATP FT synthase alpha/beta family, score 564.10, E-value 8.9e-166" FT misc_feature 159737..159760 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 160319..160348 FT /note="PS00152 ATP synthase alpha and beta subunits FT signature" FT misc_feature 160352..160756 FT /note="Pfam match to entry PF00422 ATP-synt_A-c, ATP FT synthase Alpha chain, C terminal, score 255.80, E-value FT 2.1e-86" FT RBS 160817..160821 FT CDS 160832..161749 FT /transl_table=11 FT /gene="SCO5372" FT /gene_synonym="atpG" FT /gene_synonym="2SC6G5.16" FT /product="ATP synthase gamma chain" FT /note="2SC6G5.16, atpG, ATP synthase gamma chain (EC FT 3.6.1.34), len: 305aa; strongly similar to many eg. FT SW:P00837 (ATPG_ECOLI) ATP synthase gamma chain from FT Escherichia coli (287 aa) fasta scores; opt: 591, z-score: FT 655.5, E(): 4.9e-29, 37.4% identity in 289 aa overlap. FT Almost identical to SW:P50007 (ATPG_STRLI) ATP synthase FT gamma chain from Streptomyces lividans. Contains Pfam match FT to entry PF00231 ATP-synt, ATP synthase and Prosite match FT to PS00153 ATP synthase gamma subunit signature." FT /db_xref="GOA:Q9K4D4" FT /db_xref="HSSP:1FS0" FT /db_xref="InterPro:IPR000131" FT /db_xref="UniProtKB/Swiss-Prot:Q9K4D4" FT /protein_id="CAB94543.1" FT /translation="MGAQLRVYKRRIRSVTATKKITKAMEMIAASRVVKAQRKVAASTP FT YARELTRAVTAVGTGSNTKHPLTTEADSPSRAAVLLLTSDRGLAGAFNSNSIKAAEQLT FT ERLEREGRQVDTYIVGRRGLAHYNFRERKVVESFAGFTDEPTYADAKKVAAPLIEAIEK FT DTAEGGVDELHIVYTEFVSMMTQTAVDSRLLPLSLDEVAEESGAKDEILPLYDFEPSAE FT DVLDALLPRYVESRIYNALLQSAASKHAATRRAMKSATDNAGELINTLSRLANAARQAE FT ITQEISEIVGGASALADANAGSDN" FT misc_feature 160838..161719 FT /note="Pfam match to entry PF00231 ATP-synt, ATP synthase, FT score 368.40, E-value 7.3e-107" FT misc_feature 161675..161716 FT /note="PS00153 ATP synthase gamma subunit signature" FT CDS 161749..163185 FT /transl_table=11 FT /gene="SCO5373" FT /gene_synonym="atpD" FT /gene_synonym="2SC6G5.17" FT /product="ATP synthase beta chain" FT /note="2SC6G5.17, atpD, ATP synthase beta chain (EC FT 3.6.1.34), len: 478aa; strongly similar to many eg. FT SW:P37809 (ATPB_BACSU) ATP synthase beta chain from FT Bacillus subtilis (473 aa) fasta scores; opt: 2051, FT z-score: 2236.9, E(): 0, 67.7% identity in 470 aa overlap. FT Identical to SW:P50004 (ATPB_STRLI) ATP synthase beta chain FT from Streptomyces lividans. Contains Pfam match to entry FT PF00006 ATP-synt_ab, ATP synthase alpha/beta family, Pfam FT match to entry PF00306 ATP-synt_ab_C, ATP synthase ab C FT terminal, Prosite match to PS00152 ATP synthase alpha and FT beta subunits signature and Prosite match to PS00017 FT ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:P0A300" FT /db_xref="HSSP:1SKY" FT /db_xref="InterPro:IPR000194" FT /db_xref="UniProtKB/Swiss-Prot:P0A300" FT /protein_id="CAB94544.1" FT /translation="MTTTVETATATGRVARVIGPVVDVEFPVDAMPEIYNALHVEVADP FT AKEGELKTLTLEVAQHLGDGLVRTISMQPTDGLIRQAPVTDTGAAISVPVGDFTKGKVF FT NTLGEVLNVDEQYTGERWPIHRKAPNFDELESKTEMFETGVKVIDLLTPYVKGGKIGLF FT GGAGVGKTVLIQEMIYRVANNHDGVSVFAGVGERTREGNDLIDEMSESGVIDKTALVFG FT QMDEPPGTRLRVALAGLTMAEYFRDVQKQDVLFFIDNIFRFTQAGSEVSTLLGRMPSAV FT GYQPNLADEMGLLQERITSTRGHSITSMQAIYVPADDLTDPAPATTFAHLDATTVLSRP FT ISEKGIYPAVDPLDSTSRILDPRYIAAEHYNAAMRVKNILQKYKDLQDIIAILGIDELG FT EEDKLVVHRARRVERFLSQNTHVAKQFTGVDGSDVPLDESIAAFNAICDGEYDHFPEQA FT FFMCGGIEDLKNNAKELGVS" FT misc_feature 161797..162822 FT /note="Pfam match to entry PF00006 ATP-synt_ab, ATP FT synthase alpha/beta family, score 564.70, E-value 5.9e-166" FT misc_feature 162238..162261 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 162790..162819 FT /note="PS00152 ATP synthase alpha and beta subunits FT signature" FT misc_feature 162886..163182 FT /note="Pfam match to entry PF00306 ATP-synt_ab_C, ATP FT synthase ab C terminal, score 150.80, E-value 2.4e-41" FT RBS 163307..163311 FT CDS 163317..163691 FT /transl_table=11 FT /gene="SCO5374" FT /gene_synonym="atpC" FT /gene_synonym="2SC6G5.18" FT /product="ATP synthase epsilon chain" FT /note="2SC6G5.18, atpC, ATP synthase epsilon chain (EC FT 3.6.1.34), len: 124aa; similar to many eg. SW:P37812 FT (ATPE_BACSU) ATP synthase epsilon chain from Bacillus FT subtilis (132 aa) fasta scores; opt: 244, z-score: 304.5, FT E(): 1.7e-09, 34.7% identity in 124 aa overlap. Identical FT to SW:P50011 (ATPE_STRLI) ATP synthase epsilon chain from FT Streptomyces lividans. Contains Pfam match to entry PF00401 FT ATP-synt_DE, ATP synthase, Delta/Epsilon chain." FT /db_xref="GOA:P0A2Z6" FT /db_xref="InterPro:IPR001469" FT /db_xref="UniProtKB/Swiss-Prot:P0A2Z6" FT /protein_id="CAB94545.1" FT /translation="MAAELHVALVAADREVWSGEATLVVARTTSGDIGVMPGHQPLLGV FT LESGPVTIRTSDGGTVVAAVHGGFISFADNKLSLLAEVAELSDEIDVHRAERKLEQAKT FT EGDAHAERRADVRLRAAAGR" FT misc_feature 163323..163631 FT /note="Pfam match to entry PF00401 ATP-synt_DE, ATP FT synthase, Delta/Epsilon chain, score 93.90, E-value FT 7.1e-25" FT RBS 163819..163825 FT CDS 163828..164283 FT /transl_table=11 FT /gene="SCO5375" FT /gene_synonym="2SC6G5.19" FT /product="putative secreted protein" FT /note="2SC6G5.19, possible secreted protein, len: 151aa; FT similar to SW:Q10620 (YD12_MYCTU) hypothetical protein from FT Mycobacterium tuberculosis (147 aa) fasta scores; opt: 282, FT z-score: 358.4, E(): 1.7e-12, 38.9% identity in 144 aa FT overlap. Contains possible N-terminal signal sequence FT peptide" FT /db_xref="InterPro:IPR019675" FT /db_xref="UniProtKB/TrEMBL:Q9K4D3" FT /protein_id="CAB94546.1" FT /translation="MSMALALTVCGIVVAVVVIGLFVFGLRRRLIQRSGGTFDCSLRWD FT APKEGDTTDGKGWAYGVARYNGDRVEWYRVFSYSPRPRRVLERSAIEVAGRRLPDGEEE FT LALLSDAVILACLHRGTRLELAMSEDALTGFLAWLEAAPPGQRVNVA" FT misc_feature complement(164042..166251) FT /note="Previously sequenced as EMBL:AB017010." FT CDS complement(164302..166131) FT /transl_table=11 FT /gene="SCO5376" FT /gene_synonym="chiC" FT /gene_synonym="2SC6G5.20c" FT /product="chitinase C (putative secreted protein)" FT /note="2SC6G5.20c, chiC, chitinase C (EC 3.2.1.14) FT (putative secreted protein), len: 609aa; previously FT sequenced as TR:Q9Z9M8 (EMBL:AB017010). Strongly similar to FT others from Streptomyces spp. e.g. SW:P11220 (CHIT_STRPL) FT chitinase 63 precursor from Streptomyces plicatus (610 aa) FT fasta scores; opt: 3997, z-score: 3833.9, E(): 0, 95.1% FT identity in 611 aa overlap. Contains Pfam match to entry FT PF00704 Glyco_hydro_18, Glycosyl hydrolases family 18, Pfam FT match to entry PF00041 fn3, Fibronectin type III domain, FT Pfam match to entry PF00553 CBD_2, Cellulose binding FT domain, Prosite match to PS00561 Cellulose-binding domain, FT bacterial type, Prosite match to PS01095 Chitinases family FT 18 active site and Prosite match to PS00018 EF-hand FT calcium-binding domain. Also contains a possible FT non-cleavable N-terminal signal sequence." FT /db_xref="GOA:Q9Z9M8" FT /db_xref="HSSP:1K85" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:Q9Z9M8" FT /protein_id="CAB94547.1" FT /translation="MRFRHKAAALAATLALPLAGLVGLASPAQAATSATATFAKTSDWG FT TGFGGSWTVKNTGTTSLSSWTVEWDFPTGTKVTSAWDATVTNSGDHWTAKNVGWNGTLA FT PGASVSFGFNGSGPGSPSNCKLNGGSCDGTSVPGDAAPSAPGTPTASNITDTSVKLSWS FT AATDDKGVKNYDVLRDGAKVATVTGTTYTDNGLTKGTAYSYSVKARDTADQTGPASGAV FT KVTTTGGGDGGNPGTGAEVKMGYFTNWGVYGRNYHVKNLVTSGSADKITHINYAFGNVQ FT GGKCTIGDSYADYDKAYTADQSVDGVADTWDQPLRGNFNQLRKLKAKYPNIKILYSFGG FT WTWSGGFPDAVKNPAAFAKSCHDLVEDPRWADVFDGIDLDWEYPNACGLSCDETSAPNA FT FSSMMKAMRAEFGQDYLITAAVTADGSDGGKIDAADYGEASKYIDWYNVMTYDFFGAWA FT KNGPTAPHSPLTAYDGIPQQGFNTADAMAKFKSKGVPADKLLIGIGFYGRGWTGVTQSA FT PGGTATGPATGTYEAGIEDYKVLKNSCPATGTIAGTAYAHCGSNWWSYDTPATIKSKMD FT WAEQQGLGGAFFWEFSGDTTNGELVSAIDSGLK" FT misc_feature complement(164350..165414) FT /note="Pfam match to entry PF00704 Glyco_hydro_18, Glycosyl FT hydrolases family 18, score 642.90, E-value 8.2e-191" FT misc_feature complement(164824..164862) FT /note="PS00018 EF-hand calcium-binding domain" FT misc_feature complement(164986..165012) FT /note="PS01095 Chitinases family 18 active site" FT misc_feature complement(165322..168862) FT /note="Region previously sequenced as EMBL:AF102271" FT misc_feature complement(165475..165708) FT /note="Pfam match to entry PF00041 fn3, Fibronectin type FT III domain, score 66.30, E-value 6.4e-16" FT misc_feature complement(165739..166032) FT /note="Pfam match to entry PF00553 CBD_2, Cellulose binding FT domain, score 176.90, E-value 2.6e-50" FT misc_feature complement(165796..165837) FT /note="PS00561 Cellulose-binding domain, bacterial type" FT RBS complement(166137..166143) FT CDS complement(166279..166920) FT /transl_table=11 FT /gene="SCO5377" FT /gene_synonym="chiR" FT /gene_synonym="2SC6G5.21c" FT /product="chitinase two-component response regulator" FT /note="2SC6G5.21c, chiR, chitinase two-component response FT regulator, len: 213 aa; previously sequenced as TR:Q9Z677 FT (EMBL:AF102271). Similar to many others eg. TR:Q9RHU6 FT (EMBL:AB016841) response regulator from chitinase FT regulatory system in Streptomyces thermoviolaceus (213 aa) FT fasta scores; opt: 956, z-score: 1085.4, E(): 0, 77.0% FT identity in 213 aa overlap. Contains Pfam match to entry FT PF00072 response_reg, Response regulator receiver domain, FT Pfam match to entry PF00196 GerE, Bacterial regulatory FT proteins, luxR family, Prosite match to PS00622 Bacterial FT regulatory proteins, luxR family signature and a FT helix-turn-helix motif (residue 169-190)." FT /db_xref="GOA:Q7AKG1" FT /db_xref="HSSP:1A04" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q7AKG1" FT /protein_id="CAB94548.1" FT /translation="MIRVLVAEDQSAVRAGLVLILGSAPDIEVVGEAADGEQAVALARE FT LRPDLVLMDVQMPRMDGVSATRIVVGEQLADVLVLTTFDLDEYVFGALRAGAAGFLLKN FT TDARDLLAAVRTVAGGEGIVAPAVTRRLIAEFAAKPVREPTADPAVLRELTRREREVLS FT CLGEGLSNAAVAERLDMAEATVKTHVSRLLGKLGLRSRVQAAVLAQELGI" FT misc_feature complement(166282..166470) FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 71.20, E-value FT 2.3e-17" FT misc_feature complement(166336..166419) FT /note="PS00622 Bacterial regulatory proteins, luxR family FT signature" FT misc_feature complement(166579..166917) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 115.50, E-value 1e-30" FT CDS complement(166917..168113) FT /transl_table=11 FT /gene="SCO5378" FT /gene_synonym="chiS" FT /gene_synonym="2SC6G5.22c" FT /product="chitinase two-component sensor kinase" FT /note="2SC6G5.22c, chiS, chitinase two-component sensor FT kinase, len: 398aa; previously sequenced as TR:Q9Z678 FT (EMBL:AF102271). Similar to many others eg. TR:Q9RHU7 FT (EMBL:AB016841) sensor kinase from chitinase regulatory FT system in Streptomyces thermoviolaceus (448 aa) fasta FT scores; opt: 1663, z-score: 1797.1, E(): 0, 67.4% identity FT in 396 aa overlap. Contains possible membrane-spanning FT hydrophobic regions." FT /db_xref="GOA:Q7AKG0" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q7AKG0" FT /protein_id="CAB94549.1" FT /translation="MAVRLPRPRRFDVYAASAGLLGGLLLWGIGLGVRPADEPVVLFDG FT RWPLLAPLAVMAGCELLRRAAPRTGLLIGTVALVADTLTQGSLVTVIMYTDLIYAAVLY FT GPPASARRIPWITGLLTVASTLVPFAVWRVPETLLVGVAVGVVSFAPASTGLIVRNHRE FT AADAALLRAEQTALLAEMDRAQAVTAERSRMARELHDMVANHLSAIAIHSTAALSLDDA FT ATTRQALGVIRENSVAGLAEMRRLIGILRDQGGDTGPAAAPTLDGLGALVEGARANGLD FT VTLDTAPGENLPVPVELAAYRIVQESLTNALKHASEGTVLVRLDRHEGALRVEVTSPYG FT DRDTPRAPGSGAGLVGMRERAALLHGTFEAGAVADPGPAGGKIWAVRATLPLTEGDLA" FT RBS complement(166928..166933) FT RBS complement(168115..168121) FT RBS 168253..168260 FT CDS 168266..168850 FT /transl_table=11 FT /gene="SCO5379" FT /gene_synonym="2SC6G5.23" FT /product="putative membrane protein" FT /note="2SC6G5.23, possible membrane protein, len: 194aa; FT similar to TR:O31780 (EMBL:Z99112) hypothetical protein FT from Bacillus subtilis (185 aa) fasta scores; opt: 399, FT z-score: 492.4, E(): 5.9e-20, 34.3% identity in 178 aa FT overlap. Contains possible membrane-spanning hydrophobic FT regions. Also contains Prosite match to PS00622 Bacterial FT regulatory proteins, luxR family signature but no FT similarity to any other regulators." FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9K4D2" FT /protein_id="CAB94550.1" FT /translation="MVVALIIACEVGFWVLLALGLGARYLLKWRRTGVVLLLCEPVLEL FT VLFAVTAWDLKNGAEPGWEHGLAALYIGYTVAYGHYTIRWLDGHAAHRLGGAPPPVKPP FT RYGRARAAHEGRLWLRTLLGAAVACALLQGAVWYVGDDGDVSSLRAFQWAAIRVLGIHG FT AVALGYLIWPKKAPAGTPEAAAERRKQEAHR" FT misc_feature 168461..168544 FT /note="PS00622 Bacterial regulatory proteins, luxR family FT signature" FT RBS 168834..168839 FT CDS 168847..169035 FT /transl_table=11 FT /gene="SCO5380" FT /gene_synonym="2SC6G5.24" FT /product="putative membrane protein" FT /note="2SC6G5.24, possible membrane protein, len: 62aa; FT weakly similar to TR:Q9XA75 (EMBL:AL096822) putative FT membrane protein from Streptomyces coelicolor (83 aa) fasta FT scores; opt:82, z-score: 135.0, E(): 4.7, 37.0% identity in FT 54 aa overlap. Contains possible membrane-spanning FT hydrophobic regions." FT /db_xref="UniProtKB/TrEMBL:Q9K4D1" FT /protein_id="CAB94551.1" FT /translation="MTRASKHLLEGAVTLLAGLALWLFTGDVEVPMVTLTKVGVVLMCV FT GGAQTAWGLYGAARRHV" FT CDS complement(169164..169736) FT /transl_table=11 FT /gene="SCO5381" FT /gene_synonym="2SC6G5.25c" FT /product="conserved hypothetical protein" FT /note="2SC6G5.25c, conserved hypothetical protein, len: FT 190aa; similar to many eg. SW:Q10622 (Y02Y_MYCTU) FT hypothetical protein from Mycobacterium tuberculosis (193 FT aa) fasta scores; opt: 800, z-score: 984.0, E(): 0, 65.6% FT identity in 189 aa overlap. Contains Pfam match to entry FT PF01923 DUF80, Protein of unknown function." FT /db_xref="GOA:Q9K4D0" FT /db_xref="InterPro:IPR002779" FT /db_xref="UniProtKB/TrEMBL:Q9K4D0" FT /protein_id="CAB94552.1" FT /translation="MVNLTRIYTRTGDKGTTALGDMSRVPKTDLRISAYADANEANAVI FT GTAIALGGLPEEVVKVLVRVQNDLFDVGADLSTPVVENPEYPPLRVEQFYVDKLEADCD FT RYLAEVEKLRSFILPGGTAGAALLHQACTVVRRAERSTWAALEAHGETMNPLTATYLNR FT LSDLLFILARVANKEVGDVLWVPGGER" FT misc_feature complement(169206..169718) FT /note="Pfam match to entry PF01923 DUF80, Protein of FT unknown function, score 258.50, E-value 8.8e-74" FT CDS complement(169750..170499) FT /transl_table=11 FT /gene="SCO5382" FT /gene_synonym="2SC6G5.26c" FT /product="putative ABC transporter, integral membrane FT subunit" FT /note="2SC6G5.26c, possible ABC transporter, integral FT membrane subunit, len: 249aa; similar to TR:Q53627 FT (EMBL:U43537) membrane protein involved in mithramycin FT resistance from Streptomyces argillaceus (233 aa) fasta FT scores; opt: 704, z-score: 811.8, E(): 0, 47.1% identity in FT 227 aa overlap. Contains Pfam match to entry PF01061 FT ABC2_membrane, ABC-2 type transporter and possible FT membrane-spanning hydrophobic regions." FT /db_xref="GOA:Q9K4C9" FT /db_xref="InterPro:IPR013525" FT /db_xref="UniProtKB/TrEMBL:Q9K4C9" FT /protein_id="CAB94553.1" FT /translation="MLLHDTGLVYGRYLRQSLRSRFALLFGVLMPLLYLLFFGPLLTDL FT PLGGRGSSWQVLVPGLLLQLGLFGASFAGFSIIIENGQGVVERMRVTPVSRLALLLGRV FT LRDATVFAFQAVLLVLAALVMGLRAPLPGVLIGFAFVALLTVSLASLSYALAMKVRTPQ FT EFGPTINALTMPSMLLSGLMLPMTLGPAWLDVLSHLMPFRYLVDAVRDAYVGSYATAHM FT LYGVLVALAFTALAVTVGTRVFRTAGA" FT misc_feature complement(169756..170496) FT /note="Pfam match to entry PF01061 ABC2_membrane, ABC-2 FT type transporter, score -64.30, E-value 0.0054" FT CDS complement(170520..171302) FT /transl_table=11 FT /gene="SCO5383" FT /gene_synonym="2SC6G5.27c" FT /product="putative ABC transporter, ATP-binding subunit" FT /note="2SC6G5.27c, possible ABC transporter, ATP-binding FT subunit, len: 260aa; similar to many eg. TR:Q53626 FT (EMBL:U43537) ATP-binding protein involved in mithramycin FT resistance from Streptomyces argillaceus (320 aa) fasta FT scores; opt: 901, z-score: 998.1, E():0, 59.6% identity in FT 225 aa overlap. Contains Pfam match to entry PF00005 FT ABC_tran, ABC transporter, Prosite match to PS00017 FT ATP/GTP-binding site motif A (P-loop) and Prosite match to FT PS00211 ABC transporters family signature." FT /db_xref="GOA:Q9K4C8" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9K4C8" FT /protein_id="CAB94554.1" FT /translation="MAIISTAGLARTFATRRGPVEAVRGIDLTVREGEILGFLGPNGAG FT KTTTLRMLTTLLAPTGGAATVAGHDLATDPAGVRAACGYVAQSGGVDPQITVREELVTQ FT GRLYRLSRARAAERAGELARDLGLTGLLDRRCGALSGGQRRRLDIAMALTHRPKVLFLD FT EPTTGLDPGSRADLWDLVRRLRDAHGTTVFLTTHYLDEADALSDRLVVVDGGTVVAEGT FT PAALKLEYGGSPDATLQDTFLAVTGRGAAPADATPVAV" FT misc_feature complement(170658..171206) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 221.10, E-value 1.7e-62" FT misc_feature complement(170844..170888) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(171162..171185) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 171396..172037 FT /transl_table=11 FT /gene="SCO5384" FT /gene_synonym="2SC6G5.28" FT /product="putative tetR-family transcriptional regulator" FT /note="2SC6G5.28, possible tetR-family transcriptional FT regulator, len: 213 aa; similar to many proposed FT transcriptional regulators e.g. TR:CAB88457 (EMBL:AL353815) FT putative tetR-family transcriptional regulator from FT Streptomyces coelicolor (215 aa) fasta scores; opt: 370, FT z-score: 461.9, E(): 3e-18, 36.8% identity in 209 aa FT overlap. Contains Pfam match to entry PF00440 tetR, FT Bacterial regulatory proteins, tetR family and a FT helix-turn-helix motif (residue 33-54)." FT /db_xref="GOA:Q9K4C7" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9K4C7" FT /protein_id="CAB94555.1" FT /translation="MAEGLRERKKRQTRQYISDVATGLFLERGFEAVTVAEVADAANVS FT VNTVYNYFPAKEDLFLDRSKGVIDRLSRWVRGRRDGESAAGAVLRELRDEVESVSPRVG FT LMDGYATFMKVIQDSPALRSRMWAIGQEVLLNLEHTLREETGSADDDMTPTLMAGQINW FT LHGTVLAAIGGRMVAGGKPSEVSRDMLLLLDEMEELLSEKVLNYAVRGAL" FT misc_feature 171444..171578 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 55.80, E-value FT 7.2e-13" FT RBS 172163..172166 FT CDS 172174..173022 FT /transl_table=11 FT /gene="SCO5385" FT /gene_synonym="2SC6G5.29" FT /product="putative 3-hydroxybutyryl-coA dehydrogenase" FT /note="2SC6G5.29, possible 3-hydroxybutyryl-coA FT dehydrogenase, len: 282 aa; similar to many eg. SW:P52041 FT (HBD_CLOAB) 3-hydroxybutyryl-coA dehydrogenase from FT Clostridium acetobutylicum (282 aa) fasta scores; opt: 806, FT z-score: 947.0, E(): 0, 44.6% identity in 280 aa overlap. FT Contains Pfam match to entry PF00725 3HCDH, FT 3-hydroxyacyl-CoA dehydrogenase and Prosite match to FT PS00067 3-hydroxyacyl-CoA dehydrogenase signature." FT /db_xref="GOA:Q9K4C6" FT /db_xref="HSSP:3HDH" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9K4C6" FT /protein_id="CAB94556.1" FT /translation="MARKLAVIGAGLMGSGIAQVSAQAGWEVVLRDVTDEALRRGTDGI FT RASYDKFVAKGRLDADDAEAALGRITATTDLDAAADADVVVEAVFEKLEVKHEIFRTLD FT KLVKDGAILASNTSAIPITKIAAVTERPERVVGTHFFSPVPMMQLCELVRGYKTSDETL FT ATAREFAESTGKTCIVVNRDVAGFVTTRLISALVVEAAKLYESGVATAEDIDLACKLGF FT GHAMGPLATADLTGVDILLHATGNIYTESQDEKFAPPELMRRMVDAGDIGRKSGQGFYK FT H" FT misc_feature 172186..173019 FT /note="Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA FT dehydrogenase, score 397.80, E-value 1.1e-115" FT misc_feature 172720..172794 FT /note="PS00067 3-hydroxyacyl-CoA dehydrogenase signature" FT misc_feature 173213..173518 FT /note="Pfam match to entry PF01740 SpoIIAA, SpoIIAA family, FT score 40.70, E-value 3.3e-08" FT CDS 173213..173536 FT /transl_table=11 FT /gene="SCO5386" FT /gene_synonym="2SC6G5.30" FT /product="putative anti-sigma factor antagonist" FT /note="2SC6G5.30, possible anti-sigma factor antagonist, FT len: 107aa; similar to many eg. SW:P95842 (RSBV_STAAU) FT anti-sigma B factor antagonist from Staphylococcus aureus FT (108 aa) fasta scores; opt: 164, z-score: 226.7, E(): FT 3.7e-05, 30.9% identity in 94 aa overlap. Contains Pfam FT match to entry PF01740 SpoIIAA, SpoIIAA family." FT /db_xref="GOA:Q9K4C5" FT /db_xref="InterPro:IPR003658" FT /db_xref="UniProtKB/TrEMBL:Q9K4C5" FT /protein_id="CAB94557.1" FT /translation="MHIRGDHVELVVGGRLDVRSAADARTVLHSAVDDGVGDLVLDLSE FT LDSWDATGLGVIMGAHRRAGRCGRRLVLRGVPPQMQRLLVATRLHRILAIEGGIGVETL FT PRV" FT CDS 173770..176394 FT /transl_table=11 FT /gene="SCO5387" FT /gene_synonym="2SC6G5.31" FT /product="large hypothetical protein" FT /note="2SC6G5.31, unknown, len: 874 aa" FT /db_xref="InterPro:IPR000276" FT /db_xref="UniProtKB/TrEMBL:Q9K4C4" FT /protein_id="CAB94558.1" FT /translation="MDPNNRGPEEYGQDGDHQAPRPRPHRDPITSDFGQHAPALARTVQ FT LVSGDFLLTVNPVDGSEIEVCPPAERPARPEKLTAAERADAERAARPPVPPGPVRTVLG FT LLAREDERERLVRLLARGRSVRLTGPAGSGRTSLLDVVAEDCAGLAPDGVVRLNGHHRT FT ADDLLHDLFYAVHGAPLHRPGRTELLGHLREVGAVVVLDDAEFGGTALDELLDATPECA FT FVIGTTPDVAPPSADSAVEEVFLTGLDRSDGVELLERAAGRTLTEEEANWAGDLWFESE FT GLPLRFVQAGALLRRRDRERAGADAVDEFGVFADARPADTRPADDSPYDAAETDDVPLP FT SLGEAAAPAPLLASRLSASARATLEFAVALGGEVPHQAHLPALVGETHADAALGELADC FT GLVSPVASRYRLAAGVLTQLESAGYADAVRERATAAAQHYAWWAGHPSVTPERVCAEAD FT AVLAALAVLVPATTRTTEDEESPAVQLARTAAPAFAAGLHWSAWERALRSGTEASRLAG FT DVAEQAYFHHELGVLALCEGQLDRARTELEASVGLRGALSDRRGAVAGRRALALVADRT FT GDTPGLGSGAGAFAAAAPAAGPGAVGAGLGPTVGEEVPDARNEESASPSAGVPAPFPPL FT QPRPQSPTLVTRREPDEEPSRTVAGGIKGFARRNLVAAGAGALLVAVLGTVVTLGATSE FT NDGGDPSNEVGVNPSASQGVDDGSLGADRPSDDGQGQETPGAPTGSATPGTSGAPTATE FT SGAPSQGPSSTGSTDPGDDESPDAPGSPDEPSKSPSSPTTKPTSPKPTDTEPTDPGTPT FT ESDGTSPTPTETETTSPSTPETSDTASGADSPPATVSQSSTEDTGTGTGAPAGSDPATG FT QII" FT CDS complement(176495..177250) FT /transl_table=11 FT /gene="SCO5388" FT /gene_synonym="2SC6G5.32c" FT /product="conserved hypothetical protein" FT /note="2SC6G5.32c, conserved hypothetical protein, len: 251 FT aa; similar to many eg. SW:Q10634 (Y036_MYCTU) hypothetical FT protein from Mycobacterium tuberculosis (226 aa) fasta FT scores; opt: 1161, z-score: 1353.2, E(): 0, 76.1% identity FT in 226 aa overlap. Contains Pfam match to entry PF01939 FT DUF91, Protein of unknown function." FT /db_xref="InterPro:IPR002793" FT /db_xref="UniProtKB/Swiss-Prot:Q9K4C3" FT /protein_id="CAB94559.1" FT /translation="MGEVGQRTPVPGYGRIASGPARRVALPTMRLVIARCSVDYAGRLT FT AHLPSAPRLILVKADGSVSIHADDRAYKPLNWMSPPCALKEGTGEEEGVWTVVNKAGEK FT LIITMEEILHDSSHELGVDPGLIKDGVEAHLQELLADRIDTLGEGYTLIRREYMTAIGP FT VDILCRDAQGGTVAVEIKRRGEIDGVEQLTRYLELLNRDPHLAPVRGVFAAQEIKPQAR FT VLATDRGIGCQVLDYDALRGIEDDKLRLF" FT misc_feature complement(176498..177166) FT /note="Pfam match to entry PF01939 DUF91, Protein of FT unknown function, score 402.20, E-value 4.9e-117" FT CDS 177447..177839 FT /transl_table=11 FT /gene="SCO5389" FT /gene_synonym="2SC6G5.33" FT /product="hypothetical protein 2SC6G5.33" FT /note="2SC6G5.33, unknown, len: 130 aa" FT /db_xref="UniProtKB/TrEMBL:Q9K4C2" FT /protein_id="CAB94560.1" FT /translation="MSLDVSPALLEQAERGEVDEADFVDCVRTSLPYAWEMVSSLVAQL FT KVDGGAFADNQTPPPDEQARGQLLRALASDAIRGALQRHFGVRLAFQNCHRVAVFPLDS FT SVDETLTKFTSVRSQLLNQSPELRDC" FT CDS complement(177918..178946) FT /transl_table=11 FT /gene="SCO5390" FT /gene_synonym="2SC6G5.34c" FT /product="putative alkanal monooxygenase (luciferase)" FT /note="2SC6G5.34c, possible alkanal monooxygenase FT (luciferase), len: 342aa; similar to luciferase alpha chain FT from many eg. SW:P19839 (LXA1_PHOLU) alkanal monooxygenase FT alpha chain (EC 1.14.14.3) (bacterial luciferase alpha FT chain) from Photorhabdus luminescens (Xenorhabdus FT luminescens) (360 aa) fasta scores; opt: 442, z-score: FT 520.4, E(): 1.6e-21, 30.1% identity in 359 aa overlap. FT Contains Pfam match to entry PF00296 bac_luciferase, FT Bacterial luciferase." FT /db_xref="GOA:Q9K4C1" FT /db_xref="HSSP:1LUC" FT /db_xref="InterPro:IPR016048" FT /db_xref="UniProtKB/TrEMBL:Q9K4C1" FT /protein_id="CAB94561.1" FT /translation="MRVGSFVLGAQFPGQGQGEALHRAVRSAEVAEEAGLDTVWLAEHH FT FVPYGTCPSAVTLAALLLGRTRRVRVGTAVSVLPTVHPVALGEQAALLHVTSGGRFSLG FT VGRGGPWVDLEVFGAGLEAYEKGFPDSLDLLLRWLREPAVGASGDRYRFREVPVVPRPS FT ESLSEEPGPEVVVACTSPSSVRMAAERGLPMLLGMHVGDEEKAEMVALWRRHARAAGRP FT AAEIHGAGHVSAGVCQIADRRTDAAETLLKAMPGWLRQGLGAHVTVDGRARQMRDPHAY FT TELLCGLHPVGTPRLCADRLAATGERTGISRFALLVEGSGDLAATEENVRRLGAEVLPQ FT LR" FT misc_feature complement(178359..178946) FT /note="Pfam match to entry PF00296 bac_luciferase, FT Bacterial luciferase, score 102.10, E-value 4.6e-32" FT CDS 179203..179535 FT /transl_table=11 FT /gene="SCO5391" FT /gene_synonym="2SC6G5.35" FT /product="putative ATP/GTP-binding protein, doubtful CDS" FT /note="2SC6G5.35, possible ATP/GTP-binding protein, FT doubtful CDS, len: 110aa; contains Prosite match to PS00017 FT ATP/GTP-binding site motif A (P-loop)." FT /db_xref="UniProtKB/TrEMBL:Q9K4C0" FT /protein_id="CAB94562.1" FT /translation="MSPRRNRPKGAGSSGRSAEEDGSGRYGGWQSAENWQGEEWSVRHV FT AGASAQGKSYRCPGCDQLIPDGVPHVVAWPAHSGVDDRRHWHKACWNAKDRRTTRVQRS FT RNAPRF" FT misc_feature 179341..179364 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(179544..180413) FT /transl_table=11 FT /gene="SCO5392" FT /gene_synonym="2SC6G5.36c" FT /product="putative ABC transporter integral membrane FT subunit" FT /note="2SC6G5.36c, possible ABC transporter integral FT membrane subunit, len: 289aa; similar to many membrane FT proteins of eg. TR:O86630 (EMBL:AL031155) probable integral FT membrane protein from Streptomyces coelicolor (279 aa) FT fasta scores; opt: 424, z-score: 479.6, E(): 3.1e-19, FT 33.9% identity in 274 aa overlap. Contains possible FT membrane-spanning hydrophobic regions and lies immediately FT downstream of a possible ABC transporter ATP-binding FT subunit." FT /db_xref="UniProtKB/TrEMBL:Q9K4B9" FT /protein_id="CAB94563.1" FT /translation="MSTPQPPTQQAAPDWHAAPGSPFPTYTSPIPVVRTTLVHALASEW FT TKIKSVRSTLWTLGVFVLLVLGIGLLTGAVVASSDSDLAGESALSLGFFGLLLGSMCVI FT TLGVLTTASEYGTGMIRTTMTACPSRGRVLAAKGIVFFLVAFVVTLICATLVGLAHVSM FT LEGNGAENPTGAEWLKGTVGVALYVALLGLLSLAMGSIIRHSAGAITIMIGVLLAPLVI FT ALFMFSESLKDVQQALFEYSIPNQMSIFYANSLSESGPSGWDPLWIVLGVTAAAFAAAF FT ALLEKRDV" FT CDS complement(180410..181681) FT /transl_table=11 FT /gene="SCO5393" FT /gene_synonym="2SC6G5.37c" FT /product="putative ABC transporter ATP-binding subunit" FT /note="2SC6G5.37c, possible ABC transporter ATP-binding FT subunit, len: 423aa; similar to many eg. TR:Q9S6T6 FT (EMBL:AL035654) putative ABC transporter ATP-binding FT protein from Streptomyces coelicolor (317 aa) fasta scores; FT opt: 1132, z-score: 771.9, E(): 0, 60.2% identity in 309 aa FT overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC FT transporter and Prosite match to PS00017 ATP/GTP-binding FT site motif A (P-loop)." FT /db_xref="GOA:Q9K4B8" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9K4B8" FT /protein_id="CAB94564.1" FT /translation="MIEAVGLTKRYGDKTAVYNLSFQVRPGAVTGFLGPNGSGKSTTMR FT MILGLDNPTAGHVTIGGHPYRRLPNAARHVGALLDAKAVHGGRAARNHLLSLAQLSGIP FT ARRVDEVLGVVGLQDVAKRRSKGFSLGMGQRLGIAAALLGDPQVLLFDEPVNGLDPEGI FT HWVRNLMKALAAEGRTVFVSSHLMSEMALTADHLIVIGRGQLMADMSVTDFISANSADF FT ARVRTPDTEPQLREKLTSALTEAGGHVLPEQDGALRVTGLALPRISDIAHDTDVRLWEL FT SPHQASLEEAYMRMTQGAVDYRSTADQKAGLQQPLPPGAQPPMPVAGQGQPGWYAPPPP FT QQGGQPFAAPQGAPGQAPAGPYGAPVAPGAVPGGQPANPYAARQAPQAPPMPQAPAGAP FT TPPAAGPAPAAAPVTDPTKPEDAR" FT misc_feature complement(181073..181603) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 153.40, E-value 3.8e-42" FT misc_feature complement(181559..181582) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(181830..182606) FT /transl_table=11 FT /gene="SCO5394" FT /gene_synonym="2SC6G5.38c" FT /product="putative ABC transporter integral membrane FT subunit" FT /note="2SC6G5.38c, possible ABC transporter integral FT membrane subunit, len: 256aa; similar to many membrane FT proteins of eg. TR:O86630 (EMBL:AL031155) probable integral FT membrane protein from Streptomyces coelicolor (279 aa) FT fasta scores; opt: 504, z-score: 572.6, E(): 2e-24, 37.6% FT identity in 258 aa overlap.. Contains possible FT membrane-spanning hydrophobic regions and lies immediately FT downstream of a possible ABC transporter ATP-binding FT subunit." FT /db_xref="UniProtKB/TrEMBL:Q9K4B7" FT /protein_id="CAB94565.1" FT /translation="MSMAATQVVRSEWTKIRSVASTVWTLGLAVVVTIALGMLISALSK FT NEFGDMSRRDQLSFDPTFISFAGTSLGQLAMIVFGVLVVGNEYSSGMIRTSLAAVPRRG FT TFLFSKIAVATALALVVAMVTSFATFFLGQAMLGDLKASIGDPGVLRAVFGGGLYMTLI FT AMFSMGVAAMLRSPMLSLGILMPFFFLISNILGNVPATEKVGRFLPDQAGSKIMQVVTP FT IDDDVPYGPWGGLGIMALWVIAALVGGYAVLKRRDA" FT CDS complement(182603..183643) FT /transl_table=11 FT /gene="SCO5395" FT /gene_synonym="2SC6G5.39c" FT /product="putative ABC transporter ATP-binding subunit" FT /note="2SC6G5.39c, possible ABC transporter ATP-binding FT subunit, len: 346aa; similar to many eg. TR:Q9S6T6 FT (EMBL:AL035654) putative ABC transporter ATP-binding FT protein from Streptomyces coelicolor (317 aa) fasta scores; FT opt: 1180, z-score: 1223.8, E(): 0, 58.5% identity in 316 FT aa overlap. Contains Pfam match to entry PF00005 ABC_tran, FT ABC transporter and Prosite match to PS00017 FT ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q9K4B6" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9K4B6" FT /protein_id="CAB94566.1" FT /translation="MSLGWQRASSRSSVVAMIELEGLTKRYGEKVAVNNLSFTVRPGII FT TGFLGPNGAGKSTTMRMVLGLDRPTAGDVRIDGKHYDELKDPLTYIGALLEAKAWHGGR FT SAYNHLLCLAQSNGIPASRVRQVLDTVGLSAVARKKTKGFSLGMGQRLGIAGALLGDPR FT ILMFDEPVNGLDPEGIHWIRNLMKTLASQGRTVFVSSHLMSEMALTADHLVVIGQGRLL FT ADTSMAEFIAENSRSYVRIRTPQREQLLDALHAAGVTVVESGEGVLEVDGDKSETVGEL FT AARHQVVLYELSPQRASLEEAFMQLTAESVEYHAHDGQPPGAVPQQQQPPGQPPQQPWG FT SDWKRG" FT misc_feature complement(182987..183517) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 142.30, E-value 8.6e-39" FT misc_feature complement(183473..183496) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(183719..184651) FT /transl_table=11 FT /gene="SCO5396" FT /gene_synonym="2SC6G5.40c" FT /product="putative cellulose-binding protein" FT /note="2SC6G5.40c, probable cellulose-binding protein, len: FT 310aa; strongly similar to TR: (EMBL:) AbpS avicel-binding FT protein from Streptomyces reticuli (311 aa) fasta scores; FT opt: 1777, z-score: 1598.0, E(): 0, 93.2% identity in 311 FT aa overlap. Contains a possible membrane-spanning FT hydrophobic region close to the N-terminus and possible FT coiled-coil regions throughout." FT /db_xref="UniProtKB/TrEMBL:Q9K4B5" FT /protein_id="CAB94567.1" FT /translation="MSDTSPYGFELVRRGYDRAQVDERISKLVSDRDSALARITALEKR FT IEELHLETQNAQAQVNDAEPSYAGLGARVEKILRLAEEEAKDLREEARRAAEQHRELAE FT SSAQQVRNDAESYAAERKAKAEDEGVRIVEKAKGDASQLRSEAQKDAQSKRDEADALFE FT ETRAKAAQAAADFETNLAKRREQSERDLASRQAKAEKRLAEIEHRAEQLRLEAEKLRTD FT AERRARQTVETAQRQSEDIVADANAKADRIRSESERELAALTNRRDSINAQLTNVREML FT ASLTGAAVAAAPSVEDESVSRGVPAQQSR" FT CDS complement(184859..188839) FT /transl_table=11 FT /gene="SCO5397" FT /gene_synonym="SC8F4.01c" FT /product="large Ala/Glu-rich protein" FT /note="SC8F4.01c, large Ala/Glu-rich protein, len: 1326 aa; FT hydrophilic with strong potential for coiled-coil structure FT throughout." FT /db_xref="UniProtKB/TrEMBL:Q9L2C3" FT /protein_id="CAB70627.1" FT /translation="MRGYESQEREPAADVDHLSRFEAEMKRLKTEREKAIQHAEDLGYQ FT VEVLRAKLHEARRTIMSRPAFDGGDIGYQAEQLLRNAQTQADQLRADAERELSQARAQT FT QRILQEHAEQAARLQAELHQEAVTRRQQLDQELAERRQTVESHVNENVAWAEQLRARTE FT QQARRLLDESRAEAEQAMAAARAEAERLTAEARQRLRSDAESARAEADQILRRARTDAE FT RLLNAASTQAQEATDHAEQLRSSTASESESTRREVQELSRAAEQRMSEAEEALRKAQAE FT AEKVVAQAEEAAAKALSSAEATNEQRTRTAKEQVARLVGEATKDAESTRSEAEQVVADA FT RAEAERIVAEAAEKARTITAEESATQLSKAAKTAEDVLNKASEDAKRTTKAATEEAERI FT RTEAEAEADRLRAEAHDIAAELKGAAKDDTKEYRAKTVELQEEARRLRGEAEQLRADAV FT AEGEKIRAEARKEAVAQIEEAAKTAEELLAKAKADADELRQTATADGEKVRAEAIERAT FT TLRRQAEETLERTRAEAERHRAEAAERVEELQAEAERAARELREETERAVEARQAEAAE FT ELTRLHTEAEERRSAAEEALSGAREEGERIRREAAEESERLRTEAAERVRTLQQQAETE FT AERLRTEAAADASASRAEGEAVAVRLRSEASNEAERLKTEAQESADRVRAEAQTAAERI FT AAEASEALAAAQEEAARRRREAEELLGSARQEADQERERVREQSEELLASARNRVEEAQ FT AEAVRLVEEADRRATEMVSAAEQHAAQVRESVAGLHEQAQEEITGLRSAAEHAAERTRT FT EAQEEADRVRADAYAERERASEDAGRLRREAQEETEAAKALAERTVSEAITEADRIRSD FT VSEHAQRVRTEASDAIAEAEQSASRTRADAREDANRIRSDAATQADTLITEARSEAERL FT TTETAAETDRIRTQTLAEAERVTAEAASESERVRTEAATEAERLRTETIAEADRVRAEA FT GARAEQLVSDATGEAERLRAEAADTVGSAQQHAERLRTEADRVRREAAAEAERVTTAAR FT EEAERTLDEARKDANKRRSEAAEQVDTLITETAAEADKLLTEAQQQAQKTTADAESQAD FT TMVGAARSEADRIVQEATVEGNTRVEKARTDADELLVGARRDATAIRERAEELRERLTS FT EIEELHERARREAAETMKSAGDRCDALIKAAEEQLAKAEAKAKELVSEANSEAGKVRIA FT AVKKAEGLLKEAEQKKATLVREAEELKAEAVREARATVDEGKRELEVLVRRREDINAEI FT SRVQDVLEALESFEAPGGAKDNGVKAGATVGAPRSGGKSSDG" FT CDS complement(189073..189513) FT /transl_table=11 FT /gene="SCO5398" FT /gene_synonym="SC8F4.02c" FT /product="conserved hypothetical protein" FT /note="SC8F4.02c, conserved hypothetical protein, len: FT 146aa; similar to several of undefined function eg. FT TR:O28065 (EMBL:AE000952) conserved hypothetical protein FT from Archaeoglobus fulgidus (131 aa) fasta scores; opt: 346 FT z-score: 449.3 E(): 1.3e-17 40.4% identity in 136 aa FT overlap." FT /db_xref="HSSP:1JC5" FT /db_xref="InterPro:IPR017515" FT /db_xref="UniProtKB/TrEMBL:Q9L2C2" FT /protein_id="CAB70628.1" FT /translation="MLTRIDHIGIACHDLDATVEFYRATYGFEVFHTEVNEEQGVREAM FT LKINDTSDGGASYLQLLEPTREDSAVGKWLAKNGEGVHHIAFGTADVDADAADIRDKGV FT RVLYDEPRRGSMGSRITFLHPKDCHGVLTELVTSAAVESPEH" FT RBS 189647..189654 FT CDS 189663..190868 FT /transl_table=11 FT /gene="SCO5399" FT /gene_synonym="SC8F4.03" FT /product="probable acetoacetyl-coA thiolase" FT /note="SC8F4.03, thiL, probable acetoacetyl-coA thiolase, FT len: 401aa; similar to many eg. SW:P14611 (THIL_ALCEU) FT acetoacetyl-coA thiolase from Alcaligenes eutrophus (393 FT aa) fasta scores; opt: 1272, z-score: 1344.2, E(): 0, 53.6% FT identity in 390 aa overlap. Also similar to TR:Q9XAM9 FT (EMBL:AL079355) beta-ketoadipyl-coA thiolase from FT Streptomyces coelicolor (cosmid 4C6) (400 aa) fasta scores; FT opt: 949, z-score: 919.8, E(): 0, 42.0% identity in 393 aa FT overlap. Contains Pfam match to entry PF00108 thiolase and FT Prosite matches to PS00098 Thiolases acyl-enzyme FT intermediate signature, PS00737 Thiolases signature 2 and FT PS00099 Thiolases active site." FT /db_xref="GOA:Q9L2C1" FT /db_xref="HSSP:1M3K" FT /db_xref="InterPro:IPR002155" FT /db_xref="UniProtKB/TrEMBL:Q9L2C1" FT /protein_id="CAB70629.1" FT /translation="MSSASNGTTSVIVAGARTPMGRLLGSLKSFSGADLGSFAIKAALG FT RAGIGGDQVQYVIMGQVLQAGAGQIPARQAAVKAGIPMSVPALTINKVCLSGLDAIALA FT DQLIRAGEFDVIVAGGQESMTNAPHLLPKSREGYKYGAVQMIDAMAYDGLTDSFEDIAM FT GESTEKHNTRLGIERAAQDEIAALSHQRAAAAQKNGVFDAEITPVEIPQRKGDPVLFAK FT DEGIRGDTTAESLGKLRPAFAKDGTITAGSSSQISDGAAAVVVMSRAKAEELGLEWIAE FT IGAHGNVAGPDNSLQSQPSNAIRHALKKEGLEVADLDLVEINEAFAAVAVQSMKDLGVS FT TEKVNVNGGAIALGHPIGMSGARLVLHLALELKRRGGGVGAAALCGGGGQGDALIVRVP FT GA" FT misc_feature 189681..190859 FT /note="Pfam match to entry PF00108 thiolase, Thiolase, FT score 715.90, E-value 1.9e-211." FT misc_feature 189930..189986 FT /note="PS00098 Thiolases acyl-enzyme intermediate FT signature" FT misc_feature 190695..190745 FT /note="PS00737 Thiolases signature 2." FT misc_feature 190800..190841 FT /note="PS00099 Thiolases active site" FT RBS 190894..190901 FT CDS 190905..191861 FT /transl_table=11 FT /gene="SCO5400" FT /gene_synonym="SC8F4.04" FT /product="putative transport system kinase" FT /note="SC8F4.04, possible transport system kinase, len: 318 FT aa; similar to SW:P27254 (ARGK_ECOLI) LAO/AO transport FT system kinase from Escherichia coli. Thought to FT phosphorylate the LAO/AO periplasmic binding proteins. (331 FT aa) fasta scores; opt: 562, z-score: 600.4, E(): FT 4.9e-26,35.1% identity in 271 aa overlap." FT /db_xref="GOA:Q9L2C0" FT /db_xref="InterPro:IPR005129" FT /db_xref="UniProtKB/TrEMBL:Q9L2C0" FT /protein_id="CAB70630.1" FT /translation="MQDVSSLVAQAREGRPRAVARLISLVEGASPQLREVMEALAPLTG FT NAYVVGLTGSPGVGKSTSTSALVTAYRKQGRRVGVLAVDPSSPFSGGALLGDRVRMSEH FT ASDPGVYIRSMATRGHLGGLAWAAPQAIRVLDAAGCDVVLVETVGVGQSEVEIASQADT FT SVVLLAPGMGDGIQAAKAGILEIGDVYVVNKADRDGADATARELNHMLGLGEARAAGDW FT RPPIVKTVAARGEGVDEVVEALEKHRAWMEERDVLTERRRARAAREVETIAVTTLRERI FT GDLHGDRRLGALAERIVAGELDPYRAADELVAGLTRG" FT RBS 192189..192193 FT CDS 192203..193507 FT /transl_table=11 FT /gene="SCO5401" FT /gene_synonym="SC8F4.05" FT /product="probable integral membrane protein" FT /note="SC8F4.05, probable integral membrane protein, len: FT 434aa; similar to many proposed transport proteins eg. FT TR:CAB59494 (EMBL:AL132648) putative transport proteins FT from Streptomyces coelicolor (405 aa) fasta scores; opt: FT 529, z-score: 545.1, E(): 5.9e-23, 35.2% identity in 392 aa FT overlap. Contains possible membrane-spanning hydrophobic FT regions." FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9L2B9" FT /protein_id="CAB70631.1" FT /translation="MSTPLSRPSYAAVLRVPHARRTFSAALVGRLSYGTVSLSLMLSLT FT RSTGSYAVAGLVMALFGATSVFLSPYRASLVDRLGPRRALLPMALLYAALLCVLAGACR FT RPGTSEAVLAVTAGLAGACTPPLGPTMRAVWAELLPDRRLLQRAYSVDGVAEELLFVSG FT PLLVGGIVAVASPVVGVVLSAVLVAVGTLAFVTSPATAALRPAGREKSDGPAAGRGGPG FT QGRALLQPVVVAAAVGVSVSAVDLLVVAFAGERGLGDGTVAWVLAALSVGSAVGGLVNG FT AVAWSSPTRARLPFFAAGVGLCLAAAGLAPGLGTLVLAVMCAGLFVAPALTTAYLIADE FT SVAPGFRVRAGAWCNTAVNAGMSVGAAAVGLLVERLPLPVCFAVAGAVAAAAALVPGYR FT RGAARPAGRAGGTGGAAQSSSVSSELPESSASSES" FT CDS complement(193450..194223) FT /transl_table=11 FT /gene="SCO5402" FT /gene_synonym="SC8F4.06c" FT /product="putative Asp-rich hydrophilic protein (putative FT membrane protein)" FT /note="SC8F4.06c, Asp-rich hydrophilic protein (putative FT membrane protein), len: 257 aa. Contains possible FT hydrophobic membrane spanning region" FT /db_xref="GOA:Q9L2B8" FT /db_xref="InterPro:IPR005075" FT /db_xref="UniProtKB/TrEMBL:Q9L2B8" FT /protein_id="CAB70632.1" FT /translation="MKRNIVIAAVTAAALIGGGTATALATTGDDDRGTASRADVADVAD FT APAVTVSDDGGVRDEADDRDDDRRDDDRRDDSRAAAAKVTAADAVAAALADTPGTAVSA FT ELDDEDDDGDDGDDRRERAAWEVDVLAGDGTWHSVRVDPATGKVLGSERDDDEDDTAEV FT RAALKGASVDAAEAAKAAAGHGTVTSVELDDDGDHGDGRPAWEVETRASGEGGQDWRVD FT LKTGKVTADRSDEAHGSHDSDDADDSGSSDDTDDD" FT RBS complement(194231..194235) FT misc_feature 194348..194683 FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 120.30, E-value 3.7e-32" FT CDS 194348..195016 FT /transl_table=11 FT /gene="SCO5403" FT /gene_synonym="SC8F4.07" FT /product="probable two-component system response regulator" FT /note="SC8F4.07, probable two-component system response FT regulator, len: 222 aa; similar to many e.g. SW:Q02540 FT (COPR_PSESM) CopR transcriptional activator protein from FT Pseudomonas syringae (pv. tomato) (227 aa) fasta scores; FT opt: 621, z-score: 735.4, E(): 0, 45.7% identity in 223 aa FT overlap. Contains a Pfam match to entry PF00072 FT response_reg, Response regulator receiver domain and Pfam FT match to entry PF00486 trans_reg_C, Transcriptional FT regulatory protein, C terminal." FT /db_xref="GOA:Q9L2B7" FT /db_xref="HSSP:1KGS" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9L2B7" FT /protein_id="CAB70633.1" FT /translation="MRLLIVEDEKRLAVSLAKGLTAEGYAVDVVHDGLEGLHRAGEGVY FT DLVILDIMLPGLNGYRVCAALRAAGHDVPILMLTAKDGEYDEAEGLDTGADDYLTKPFS FT YVVLVARVKALLRRRGQGAGASPVHVHGDLRVDTAARRVFLGEDEATLTAKEFAVLEQL FT VVRAGQVVSKAEILEHVWDFAYDGDPNIVEVYVSALRRKLRAGLIRTVRGAGYRLETGR FT " FT misc_feature 194789..194992 FT /note="Pfam match to entry PF00486 trans_reg_C, FT Transcriptional regulatory protein, C terminal, score FT 76.30, E-value 1.8e-21" FT RBS 195001..195004 FT CDS 195013..196449 FT /transl_table=11 FT /gene="SCO5404" FT /gene_synonym="SC8F4.08" FT /product="probable two-component sensor kinase" FT /note="SC8F4.08, probable two-component sensor kinase, len: FT 478 aa; similar to many proposed two-component sensor FT kinases eg. SW:P18392 (RSTB_ECOLI) sensor protein RstB from FT Escherichia coli (433 aa) fasta scores; opt: 379, z-score: FT 410.8, E(): 1.8e-15, 35.6% identity in 239 aa overlap. FT Contains Pfam match to entry PF00672 DUF5, Domain found in FT bacterial signal proteins and Pfam match to entry PF00512 FT signal, Histidine kinase." FT /db_xref="GOA:Q9L2B6" FT /db_xref="HSSP:1ID0" FT /db_xref="InterPro:IPR003660" FT /db_xref="UniProtKB/TrEMBL:Q9L2B6" FT /protein_id="CAB70634.1" FT /translation="MSRLFASVRARATLAATLVVAVALVAAGTAVLLSLRSNLLGEAGT FT QAERSAREVATELAVGTPYADLSLDVDDRPVQVVDDDGVLVAASEDLERISGTGVDAVK FT PRPAASPGGEDDDADDDSGESLEPGEIGGRITVSDGSATIDGDTEDYRFAAVPVKTEDR FT GTLTVYAGAPLSAEHGAVNTALTVMLIGFPLLLAVVAWVTWLVTRRALRPVEGIRREMA FT AITASEDLARRVPVPGTHDEVARLATTTNETLAALESSVERQRGFVADASHELRSPIAS FT LRTQLEVAAAHPELLDLDGAVADTVRLQRLAADLLLLARLDAGERPADARVDLAALARE FT AAEGRAGVRVRGDEGVVSAAGSRGQLGRVLANLLDNAERHARSVVEVSVRWDGDTALVA FT VTDDGEGVPAADRERIFERFVRLDDARSRDDGGAGLGLAIARDVAVRHGGTLTVHDAPA FT GGALFELRLPGDRAGTARDM" FT misc_feature 195574..195789 FT /note="Pfam match to entry PF00672 DUF5, Domain found in FT bacterial signal proteins, score 41.80, E-value 1.5e-08" FT misc_feature 195829..196416 FT /note="Pfam match to entry PF00512 signal, Histidine FT kinase, score 143.30, E-value 4.4e-39" FT CDS complement(196458..196934) FT /transl_table=11 FT /gene="SCO5405" FT /gene_synonym="SC8F4.09c" FT /product="putative transcriptional regulator" FT /note="SC8F4.09c, probable transcriptional regulator, len: FT 158 aa; similar to many e.g. TR:Q9X5U1 (EMBL:AF127374) from FT Streptomyces lavendulae (163 aa) fasta scores; opt: 382, FT z-score: 481.8, E(): 2e-19, 43.4% identity in 152 aa FT overlap and SW:P42195 (PECS_ERWCH) regulatory protein PecS FT from Erwinia chrysanthemi fasta scores; opt: 172, z-score: FT 225.1, E(): 3.9e-05, 28.7% identity in 136 aa overlap. FT Contains Pfam match to entry PF01047 MarR, MarR family and FT helix-turn-helix motif Score 1270 (+3.51 SD) in ID at FT residue 60." FT /db_xref="GOA:Q9L2B5" FT /db_xref="HSSP:1LNW" FT /db_xref="InterPro:IPR000835" FT /db_xref="UniProtKB/TrEMBL:Q9L2B5" FT /protein_id="CAB70635.1" FT /translation="METETATRWLTDTEQCAWRTHLEVNRLLTHQLEKDLQPFGLTMND FT YEILVNLSESEGDRMRMSDLATATMQSKSRLSHQITRMENANLVRRENCESDRRGLFAV FT LTEHGLETMRKVAPHHVASVRRHFIDLLAPEDLTELDKALKPIAEHLRGQRGRP" FT misc_feature complement(196494..196814) FT /note="Pfam match to entry PF01047 MarR, MarR family, score FT 60.20, E-value 4.3e-14" FT RBS complement(196944..196949) FT CDS complement(197036..197812) FT /transl_table=11 FT /gene="SCO5406" FT /gene_synonym="SC8F4.10c" FT /product="hypothetical protein" FT /note="SC8F4.10c, hypothetical protein, len: 258 aa; FT similar to TR:AAF10203 (EMBL:AE001920) hypothetical protein FT from Deinococcus radiodurans (254 aa) fasta scores; opt: FT 157, z-score: 174.0, E(): 0.028, 27.8% identity in 245 aa FT overlap. Also weakly similar to the neighbouring FT hypothetical CDSs SC8F4.11c and SC8F4.12c." FT /db_xref="InterPro:IPR002838" FT /db_xref="UniProtKB/TrEMBL:Q9L2B4" FT /protein_id="CAB70636.1" FT /translation="MSTVHHDPATLPADDNVNAYTFCVELKGSQWFLQKGKMIAYYGTI FT DFNGIGHGRLDRLVRTSFHSPLHASDWVVAEGSGKMLLADRAFDVNSYDLEDGNLTIRS FT GNLLAFQPSLALKQSIVPGFLTLIGTGKFVAASNGPVVFMEPPIRVDPQALVGWADCPS FT PCHHYDHGYMTGLLGGLRAMTGLGGASGEEHQFEFVGAGTVLLQSSEALMAEQAVGAPP FT QQAGVPGAGAPGASGGRSGVPGLPGQLGDLQRRFGL" FT CDS complement(197809..198468) FT /transl_table=11 FT /gene="SCO5407" FT /gene_synonym="SC8F4.11c" FT /product="conserved hypothetical protein" FT /note="SC8F4.11c, hypothetical protein, len: 219 aa; weakly FT similar to many e.g. TR:AAF10203 (EMBL:AE00192) FT hypothetical protein from Deinococcus radiodurans (254 aa) FT fasta scores; opt: 388, z-score: 453.5, E(): 7.5e-18, 36.9% FT identity in 214 aa overlap. Also weakly similar to the FT neighbouring hypothetical CDSs SC8F4.10c and SC8F4.12c" FT /db_xref="InterPro:IPR002838" FT /db_xref="UniProtKB/TrEMBL:Q9L2B3" FT /protein_id="CAB70637.1" FT /translation="MCEMAFEEINSKMVRATVAPGQRLFSQRGAMLAYQGEVSFTPNLR FT GGQGGVMSMIGRRVANEDTPLMTVEGSGTVLFGHGGHHVQVINLSGDTLYVEADRLLAF FT EGTLEQSTVFLGSQGGVMGMVRGQVSGQGLFTTSLKGHGSVAVMAHGGVFEVPITPQRP FT VRVDPQAYVAHHGDVRNKLSTALGWRDMVGRGSGEAFQLELSGSGTVFVQASEEKL" FT RBS complement(197820..197824) FT CDS complement(198461..199180) FT /transl_table=11 FT /gene="SCO5408" FT /gene_synonym="SC8F4.12c" FT /product="conserved hypothetical protein" FT /note="SC8F4.12c, hypothetical protein, len: 239 aa; weakly FT similar to many e.g. TR:AAF10203 (EMBL:AE00192) FT hypothetical protein from Deinococcus radiodurans (254 aa) FT fasta scores; opt: 441, z-score: 528.2, E(): 5.1e-22, 33.2% FT identity in 202 aa overlap. Also weakly similar to the FT neighbouring hypothetical CDSs SC8F4.10c and SC8F4.11c" FT /db_xref="InterPro:IPR002838" FT /db_xref="UniProtKB/TrEMBL:Q9L2B2" FT /protein_id="CAB70638.1" FT /translation="MPQGMDSGSFSTRGPCSVHPWRGYFHHVAMFRLQGSKVLAVDMTQ FT DAVKAKNGSMVAYDGEMAFKKLSGGGEGIRGMVTRRITGEQMTVMEVRGQGTCWFADRA FT SEITLVGLQGDKLYVESSNFLAADAGLRTGTSFTGTRGASQGNGLFTTTIEGHGQAAIM FT SDGPAVVLRVSAQYPLTVDPGAYVAHQGNLRQSFQSGVTFRTLFGEGGGEAFQIRFEGD FT GLVYVQPSERNTIAGDV" FT RBS complement(198469..198473) FT RBS 199268..199273 FT CDS 199278..199622 FT /transl_table=11 FT /gene="SCO5409" FT /gene_synonym="SC8F4.13" FT /product="putative membrane protein" FT /note="SC8F4.13, putative membrane protein, len: 114 aa; FT similar to TR:O31485 (EMBL:Z99106) hypothetical protein FT from Bacillus subtilis (96 aa) fasta scores; opt: 179, FT z-score: 259.7, E(): 4.7e-07, 37.4% identity in 91 aa FT overlap. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9L2B1" FT /protein_id="CAB70639.1" FT /translation="MDLKTATALRRLRLVSAPEAISFLLLLVCSVLKRTTDFNAVPAMG FT MIHGVLFVLYVIFWADAWNRAKWPLKTAALYFVLSVLPTGGFFAERKLKHEAESAVIAS FT RARQEGIVNA" FT CDS complement(199937..200062) FT /transl_table=11 FT /gene="SCO5410" FT /gene_synonym="SC8F4.14c" FT /product="hypothetical protein SC8F4.14c" FT /note="SC8F4.14c, hypothetical protein, improbable, len: 41 FT aa" FT /db_xref="UniProtKB/TrEMBL:Q9L2B0" FT /protein_id="CAB70640.1" FT /translation="MRASASEEVDQVRAVLPYVNHTIRHAPEGCITAELFCGTYE" FT CDS complement(200124..201530) FT /transl_table=11 FT /gene="SCO5411" FT /gene_synonym="SC8F4.15c" FT /product="putative integrase/recombinase" FT /note="SC8F4.15c, possible integrase/recombinase, len: FT 468aa; similar to many eg. TR:Q38184 (EMBL:X85213) FT integrase from Bacteriophage TP901-1 (485 aa) fasta scores; FT opt: 281, z-score: 318.4, E(): 2.5e-10, 26.9% identity in FT 428 aa overlap. Contains Pfam match to entry PF00239 FT recombinase, Site-specific recombinases and 2x tta Leu FT codon, possible target for bldA regulation." FT /db_xref="GOA:Q9L2A9" FT /db_xref="HSSP:2RSL" FT /db_xref="InterPro:IPR006119" FT /db_xref="UniProtKB/TrEMBL:Q9L2A9" FT /protein_id="CAB70641.1" FT /translation="MEHMTEQRAVIAIYLRLSRESDDSTSLETQRSFAHRWLLAHGYDP FT ADAVEYIDASVSGAKPLEARKGMAALMAARPTVVVAWKLDRFARSVSDFLRLVAWAEAH FT GASIATTDNAIDTTTATGRMVATVLAALAEWERNAIASRITDGHATRRSQGRWSSGRPP FT FGYRIERRDGAAYLAIDDDQAAKIRKAVAALVNGSTVAATARLTGLSEPQWRRLLKSPT FT LRGQRAHKGELVCEVDGITPVKFAEPILSAAELLKVRERMLALATGQDRAPRRATPMCS FT GMAFCHRCAGKLNGGTSDKGVPLYRCKAGHVTIYAETLDSRVESEFLTTFGSYAETVIR FT LEGGNDLSAELLEAKEQAERLAARMATAGPLMLGTLESLAQDLEDTHARLRAAHDPDVR FT EVQVATGRTMAQAWEMYDVPDRSRLLAGMGLRVSLHPRQLADRLTITWGPTPEEAPEAE FT WDGLALSEAL" FT misc_feature complement(201099..201299) FT /note="Pfam match to entry PF00239 recombinase, FT Site-specific recombinases, score 45.60, E-value 1.3e-11" FT misc_feature complement(201417..201419) FT /note="tta Leu codon, possible target for bldA regulation." FT misc_feature complement(201480..201482) FT /note="tta Leu codon, possible target for bldA regulation." FT RBS 201555..201561 FT CDS 201563..201706 FT /transl_table=11 FT /gene="SCO5412" FT /gene_synonym="SC8F4.16" FT /product="hypothetical protein" FT /note="SC8F4.16, hypothetical protein, len: 47 aa; similar FT to SW:O07734 (YC20_MYCTU) hypothetical protein from FT Mycobacterium tuberculosis (102 aa) fasta scores; opt: 193, FT z-score: 304.2, E(): 1.5e-09, 71.1% identity in 45 aa FT overlap." FT /db_xref="InterPro:IPR002767" FT /db_xref="UniProtKB/TrEMBL:Q9L2A8" FT /protein_id="CAB70642.1" FT /translation="MDVVRRAVAAVEARAPRVSLVLKADLRPGVTDGLTSKVETVERHL FT AP" FT CDS 201783..202292 FT /transl_table=11 FT /gene="SCO5413" FT /gene_synonym="SC8F4.17" FT /product="possible MarR-transcriptional regulator" FT /note="SC8F4.17, possible transcriptional regulator, len: FT 169 aa; similar to many proposed transcriptional regulators FT e.g. TR:CAB62730 (EMBL:AL133423) putative MarR-family FT transcriptional regulator from Streptomyces coelicolor (151 FT aa) fasta scores; opt: 184, z-score: 242.7, E(): 4.1e-06, FT 35.1% identity in 111 aa overlap. Contains Pfam match to FT entry PF01047 MarR, MarR family." FT /db_xref="GOA:Q9L2A7" FT /db_xref="InterPro:IPR000835" FT /db_xref="UniProtKB/TrEMBL:Q9L2A7" FT /protein_id="CAB70643.1" FT /translation="MPKPLSLSFDPIARADELWAQRWGGVPSMAAITSIMRAQQILLGE FT VDAVVKPYGLTFARYEALVLLTFSKSGELPMSKIGERLMVHPTSVTNTVDRLVRSGLVA FT KRPNPNDGRGTLATITDKGREVVEAATRDLMAMDFGLGAYDAEECGEIFAMLRPLRVAA FT GDFDED" FT misc_feature 201945..202259 FT /note="Pfam match to entry PF01047 MarR, MarR family, score FT 66.70, E-value 5e-16" FT misc_feature 202234..205238 FT /note="Region previously sequenced as EMBL:AJ237976 FT Streptomyces coelicolor icmA gene for isobutyryl-CoA mutase FT A, ORF1 and ORF2." FT CDS 202383..202712 FT /transl_table=11 FT /gene="SCO5414" FT /gene_synonym="SC8F4.18" FT /product="putative membrane protein" FT /note="SC8F4.18, putative membrane protein, len: 109 aa; FT previously sequenced therefore identical to TR:Q9X948 FT (EMBL:AJ237976). Also similar to SW:Z75555 (Y076_MYCTU) FT hypothetical protein from Mycobacterium tuberculosis (120 FT aa) fasta scores; opt: 248, z-score: 330.5, E(): 5.3e-11, FT 37.5% identity in 96 aa overlap. Contains possible FT hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9X948" FT /protein_id="CAB70644.1" FT /translation="MLTRYRVMAYVTGVLLIALCLGMIAKYVLDLGGAADFTQVVSIAH FT GWLYVIYLVFAFDLGSKAKWPVKKQLWVLLAGTVPTAAFFVERRVSQELDAKVAATEAP FT APVKA" FT CDS 202806..204506 FT /transl_table=11 FT /gene="SCO5415" FT /gene_synonym="SC8F4.19" FT /gene_synonym="icmA" FT /product="isobutyryl-CoA mutase A" FT /note="SC8F4.19, icmA, isobutyryl-CoA mutase A, len: 566 FT aa; previously sequenced and characterised as TR:Q9X949 FT (EMBL:AJ237976). Contains Pfam match to entry PF01642 FT MM_CoA_mutase, Methylmalonyl-CoA mutase." FT /db_xref="GOA:Q9X949" FT /db_xref="HSSP:1REQ" FT /db_xref="InterPro:IPR014348" FT /db_xref="UniProtKB/TrEMBL:Q9X949" FT /protein_id="CAB70645.1" FT /translation="MDAHAIEEGRLRWQARYDAARKRDADFTTLSGDPVEPVYGPRPGD FT EYEGFERIGWPGEYPFTRGLYPTGYRGRTWTIRQFAGFGNAEQTNERYKMILRNGGGGL FT SVAFDMPTLMGRDSDDPRSLGEVGHCGVAIDSAADMEVLFKDIPLGDVTTSMTISGPAV FT PVFCMYLVAAERQGVDASVLNGTLQTDIFKEYIAQKEWLFQPEPHLRLIGDLMEYCAAG FT IPAYKPLSVSGYHIREAGATAAQELAYTLADGFGYVELGLSRGLDVDVFAPGLSFFFDA FT HLDFFEEIAKFRAARRIWARWMRDVYGARTDKAQWLRFHTQTAGVSLTAQQPYNNVVRT FT AVEALAAVLGGTNSLHTNALDETLALPSEQAAEIALRTQQVLMEETGVANVADPLGGSW FT FIEQLTDRIEADAEKIFEQIKERGLRAHPDGQHPVGPITSGLLRGIEDGWFTGEIAESA FT FRYQQSLEKDDKKVVGVNVHTGSVTGDLEILRVSHEVEREQVRVLGERKDARDDAAVRG FT ALDAMLAAARSGGNMIGPMLDAVRAEATLGEICGVLRDEWGVYTEPAGF" FT misc_feature 203001..204503 FT /note="Pfam match to entry PF01642 MM_CoA_mutase, FT Methylmalonyl-CoA mutase, score 920.50, E-value 4.7e-273" FT CDS complement(204536..205549) FT /transl_table=11 FT /gene="SCO5416" FT /gene_synonym="SC8F4.20c" FT /product="putative transcriptional regulator" FT /note="SC8F4.20c, probable transcriptional regulator, len: FT 337 aa; previously partially sequenced therefore identical FT to TR:Q9X950 (EMBL:AJ237976). Similar to many proposed FT transcriptional regulators eg. TR:CAB61299 (EMBL:AL132991) FT putative AraC-family transcriptional regulator from FT Streptomyces coelicolor (311 aa) fasta scores; opt: 859, FT z-score: 986.2, E(): 0, 47.8% identity in 312 aa overlap. FT Contains Pfam match to entry PF00165 HTH_2, Bacterial FT regulatory helix-turn-helix proteins, araC family" FT /db_xref="GOA:Q9L2A6" FT /db_xref="InterPro:IPR018060" FT /db_xref="UniProtKB/TrEMBL:Q9L2A6" FT /protein_id="CAB70646.1" FT /translation="MLADAAARAAELDRLMRPAPRPGAHKVAVLALDGVYPFELGIPHR FT VLGSADGRYEVLSASVDGRPVRTDSDLTVTPAHGPEVLAGADTVIVPPYAVTAASATVP FT DPRALAALARVRPGTRLVSICTGAFLLAAAGLLDGRRATTHWALTDHFRELFPRVELDA FT DVLFVDHGDVLTSAGAASGVDVCLHLVRRDHGSEVANQVARRCVVPPYRDGGQAQYIER FT PVPPASGTGTGPTRDWALRRLDRPLSLDELAAHAAMSTRTFARRFREETGLSPGRWLTQ FT QRLRRARHLLESSDLPVERVAHEVGFATATSLRRHLAAEAGVAPSAYRRTFRASVP" FT misc_feature complement(204554..204814) FT /note="Pfam match to entry PF00165 HTH_2, Bacterial FT regulatory helix-turn-helix proteins, araC family, score FT 87.30, E-value 3.1e-22" FT CDS 205583..206602 FT /transl_table=11 FT /gene="SCO5417" FT /gene_synonym="SC8F4.21" FT /product="putative zinc-binding oxidoreductase" FT /note="SC8F4.21, possible zinc-binding oxidoreductase, len: FT 339aa; similar to many proposed oxidoreductases eg. FT TR:O85702 (EMBL:AF072709) putative oxidoreductase from FT Streptomyces lividans (313 aa) fasta scores; opt: 1311, FT z-score: 1369.8, E(): 0, 66.1% identity in 310 aa overlap. FT Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases and Prosite match to PS01162 Quinone FT oxidoreductase / zeta-crystallin signature." FT /db_xref="GOA:Q9L2A5" FT /db_xref="HSSP:1PQW" FT /db_xref="InterPro:IPR013154" FT /db_xref="UniProtKB/TrEMBL:Q9L2A5" FT /protein_id="CAB70647.1" FT /translation="MVRARADGQHGGMTSTDTPANGASPHGAPTMLALHQTALGGPEVL FT RPTELPRPAPGPGEILVAVHAAGLNPTDFKHRALKIFLPPPPLTLGWDVSGTVVETGFG FT VTLFRPGDEVFGMLPYPHGHGSHAEYVTGPARAFAAKPAGTDHVQAAALPLAALTAWQA FT LVDTAGLRAGQRVLIHAAAGGVGHLAVQIAKERGAHVTGTASAPKHAFLRELGADACVD FT YRSADFTDTEERYDVVLDTLGGETATRSVGVLRPGGIVVSLLPGDAHTGAAAERAGVRA FT VVLLVEHDHAGMRAIADLVERGSLRAHVSGTFPLAEGARAHAEGETGRTTGKLVLTVR" FT misc_feature 205691..206593 FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score 38.90, E-value 7.7e-12" FT misc_feature 206099..206164 FT /note="PS01162 Quinone oxidoreductase / zeta-crystallin FT signature" FT CDS complement(206629..207333) FT /transl_table=11 FT /gene="SCO5418" FT /gene_synonym="SC8F4.22c" FT /product="putative transcriptional regulator" FT /note="SC8F4.22c, possible transcriptional regulator, len: FT 234aa; similar to many eg. TR:Q54288 (EMBL:X86780) FT regulator of antibiotic transport complexes from FT Streptomyces hygroscopicus (204 aa) fasta scores; opt: 284, FT z-score: 301.4, E(): 2.2e-09, 31.3% identity in 211 aa FT overlap. Contains helix-turn-helix motif Score 1083 (+2.88 FT SD) in ID at residue 38." FT /db_xref="GOA:Q9L2A4" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9L2A4" FT /protein_id="CAB70648.1" FT /translation="MQSSTPAGRAGRPRSAAADTAILAATRAALVDLGWSKLALGDVAT FT RAGVAKTTLYRRWAGKNELVVDAVAELFDELELPDRGSLAADIEGVVLQFAAILARPEA FT RSGLMAVVAESTRDDALRERIRTSIVERQKRLVLEGRARAQARGELPPETDATEAARTA FT DLIFDVVAGAVVHRTLVSARAADEEWVRGLTQVLLWGLAGAAGEPGDRGDGGDGGGVGP FT GGGADAEPAAPR" FT CDS 207637..208593 FT /transl_table=11 FT /gene="SCO5419" FT /gene_synonym="SC8F4.23" FT /gene_synonym="trxA4" FT /product="putative thioredoxin" FT /note="SC8F4.23, trxA4, possible thioredoxin, len: 318aa; FT similar to many e.g. SW:P00275 (THI1_CORNE) thioredoxin C-1 FT from Corynebacterium nephridii (105 aa) fasta scores; opt: FT 297, z-score: 317.6, E(): 2.8e-10, 44.3% identity in 97 aa FT overlap. Contains Pfam match to entry PF00085 thiored, FT Thioredoxin and Prosite match to PS00194 Thioredoxin family FT active site." FT /db_xref="GOA:Q9L2A3" FT /db_xref="HSSP:2TRX" FT /db_xref="InterPro:IPR013766" FT /db_xref="UniProtKB/TrEMBL:Q9L2A3" FT /protein_id="CAB70649.1" FT /translation="MSGVVDLAAVKQAQEAKAKAEQARAEAARTGGAGAVSPADLVIDV FT DEAGFESDVLQRSTEVPVVIDFWAEWCEPCKQLSPVLERLAVEYNGRFLLAKIDVDANQ FT MLMQQFGVQGIPAVFAVVAGQALPLFQGAAGEQQIRQTLDQLVQVGEERFGLTGLVVDP FT EAEPGAERPAAPERPAGPHDAALDAAVQAMDAGDLGGAVQAYKNVLAEEPGNTEAKLGL FT AQAELLQRVQDADPQKVRREAADKPGDAQAQIAAADLDLVGGHVEDAFGRLIDTVRVTA FT GDDRDAVRLRLLELFEVVGADDPRVAAARRALARALF" FT misc_feature 207751..208080 FT /note="Pfam match to entry PF00085 thiored, Thioredoxin, FT score 86.70, E-value 7.8e-25" FT misc_feature 207826..207882 FT /note="PS00194 Thioredoxin family active site" FT RBS 209235..209241 FT CDS 209246..209893 FT /transl_table=11 FT /gene="SCO5420" FT /gene_synonym="SC8F4.24" FT /product="cholesterol esterase" FT /note="SC8F4.24, che, cholesterol esterase, len: 215aa; FT strongly similar to TR:Q53425 (EMBL:S71532) che, FT cholesterol esterase from Streptomyces lavendulae (227 aa) FT fasta scores; opt: 632, z-score: 735.9, E(): 0, 51.5% FT identity in 231 aa overlap. Contains possible hydrophobic FT membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9L2A2" FT /protein_id="CAB70650.1" FT /translation="MESQVRGGTRWKRFAVVMVPSVAATAAIGVALAQGALAASFSVSG FT QSFKVTAKELVGTGFSQYGAYDKGVDGNHAVAVSAFDKATITKMCQSVVTPNIPLIGTV FT TLRLDAGDSNKDSGKVHAKQLYIDVQDLEADATFTNIDIGVAAGAINKGPRQKQGEVEG FT KQTSPGGFAQQADQAVLKEVKQTAWATTAGTFQLSGLKMSLKKGSGEGVECY" FT RBS 209995..210002 FT CDS 210010..210567 FT /transl_table=11 FT /gene="SCO5421" FT /gene_synonym="SC8F4.25" FT /product="putative integral membrane protein" FT /note="SC8F4.25, possible integral membrane protein, len: FT 185 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9L2A1" FT /protein_id="CAB70651.1" FT /translation="MSAETPAAVGQFTRRRLQFRGWRGARPFWAGLLVLLGGFPIMYFP FT YAHLQFGNLTVAMATTAGAGSLIIGVLLVVLGVSLWFQKHVRVFAGIAAILLALVSIPV FT ANFGGFIIGFMLSLVGGALAVAWAPGGPVESGSAKGDKGEGGAFEVSGDDSASAPSLSA FT PGGDDRSGTSPANGANGRHSAG" FT CDS 210572..211942 FT /transl_table=11 FT /gene="SCO5422" FT /gene_synonym="SC8F4.26" FT /product="hypothetical hydrophilic protein" FT /note="SC8F4.26, hypothetical hydrophilic protein, len: 456 FT aa; contains possible coiled-coil region around residue FT 250" FT /db_xref="UniProtKB/TrEMBL:Q9L2A0" FT /protein_id="CAB70652.1" FT /translation="MKHGMDEETSRARTGPRHAAPRKPLFTRFQVPTGKAIALAAMPTA FT VLMGLGFTPTLALADGNDQGAPSSNSLTADEYKACVEAMADAEKDASQSPEPSPSATDD FT GKQDETEPSASPSAGDTGEKPGTDKDASSSSDSGSDDKDDTAAGDNAADGDKSEPAPSP FT SASEGKESVGASAAEPSPSESERGGLLEGIGDAIEGIFTGGEKAEETASPTPTPSASQS FT AGDDASDVVKETTDKVTGTVKDTVDGATDAASKAAEDTKDTVDKATEDAEKAAEEAKDE FT VTASPSADPSESAAVDPEDCPAATDEEGGVDNTLPVPEDPWYLEASSLTLKGASYKGIV FT EVKTASGATKKVLKYVISKGTDIGDLHQIVKDDTTGRTHHVQAAKGSTSTIRDGDTVMY FT TESISGNLLGLIPITFDPKNPPPLDIPLIYFTNVKVVQAGQFGGTLHVPGLHQYITD" FT CDS complement(212025..213455) FT /transl_table=11 FT /gene="SCO5423" FT /gene_synonym="pyk2" FT /gene_synonym="SC8F4.27c" FT /product="pyruvate kinase" FT /note="SC8F4.27c, pyk2, pyruvate kinase, len: 476 aa; FT strongly similar to many e.g. SW:Q46078 (KPYK_CORGL) FT pyruvate kinase from Corynebacterium glutamicum FT (Brevibacterium flavum) (475 aa) fasta scores; opt: 1693, FT z-score: 1907.7, E(): 0, 55.3% identity in 474 aa overlap FT and TRNEW:CAB52070 (EMBL:AL109732) pyruvate kinase from FT Streptomyces coelicolor (478 aa) fasta scores; opt: 2185, FT z-score: 2461.2, E(): 0, 69.3% identity in 473 aa overlap. FT Contains Pfam match to entry PF00224 PK, Pyruvate kinase FT and Prosite match to PS00110 Pyruvate kinase active site FT signature." FT /db_xref="GOA:Q9L299" FT /db_xref="HSSP:1E0T" FT /db_xref="InterPro:IPR018209" FT /db_xref="UniProtKB/TrEMBL:Q9L299" FT /protein_id="CAB70653.1" FT /translation="MRRSKIVCTLGPAVDSHEQLVTLIEAGMNVARFNFSHGTHAEHQG FT RYDRVRAAAKETGRAIGVLADLQGPKIRLETFAEGPVELVRGDEFTITAEDVPGDRTIC FT GTTYKGLPGDVTKGDQVLINDGNVELKVTEVEGPRVKTIVIEGGVISDHKGINLPGAAV FT NVPALSEKDVEDLRFALRMGCDLVALSFVRDAKDVADVHRVMDEEGRRVPVIAKVEKPQ FT AVDNMEDVVMAFDGVMVARGDLAVEYPLEKVPMVQKRLIELCRRNAKPVIVATQMMESM FT ITNSRPTRAEASDVANAILDGADAVMLSAESSVGAYPIETVKTMSKIVTAAEQELLSKG FT LQPLVPGKKPRTQGGSVARAAAEIADFLGGKGLVAFTQSGDTARRLSRYRAAQPILAFT FT TDESTRNQLALSWGVEPHVVPFVNTTDEMVDLVDQETARLGRFSDGDTVVITAGSPPGV FT SGTTNMVRVLHLGETRRG" FT misc_feature complement(212046..213452) FT /note="Pfam match to entry PF00224 PK, Pyruvate kinase, FT score 649.60, E-value 1.6e-191" FT misc_feature complement(212784..212822) FT /note="PS00110 Pyruvate kinase active site signature" FT CDS complement(213530..214753) FT /transl_table=11 FT /gene="SCO5424" FT /gene_synonym="ackA" FT /gene_synonym="SC8F4.28c" FT /product="acetate kinase" FT /note="SC8F4.28c, ackA, acetate kinase, len: 407 aa; FT strongly similar to many e.g. SW:P77845 (ACKA_CORGL) AckA, FT acetate kinase from Corynebacterium glutamicum FT (Brevibacterium flavum) (397 aa) fasta scores; opt: 1333, FT z-score: 1504.1, E(): 0, 52.8% identity in 388 aa overlap. FT Contains Pfam match to entry PF00871 Acetate_kinase, FT Acetokinase family and Prosite match to PS01075 Acetate and FT butyrate kinases family signature 1." FT /db_xref="GOA:Q9L298" FT /db_xref="HSSP:1G99" FT /db_xref="InterPro:IPR004372" FT /db_xref="UniProtKB/Swiss-Prot:Q9L298" FT /protein_id="CAB70654.1" FT /translation="MSSTRVLVLNSGSSSVKYQLIDMRDGERLAAGLVERIGERTSRLR FT HTLVAAGDTREQEGPIADHEAALKAVAAELGRDGLGLDSPELAAIGHRVVHGGEFFSEP FT TLIDENVLTEIERLIPVAPLHNPANLTGIRTAQALRPDLPQVAVFDTAFHTTMPESAAR FT YAIDPKIADRYRIRRYGFHGTSHAYVSRETARLLGRAPGDVNVIVLHLGNGASASAVRG FT GRCVDTSMGLTPLEGLVMGTRSGDMDPAVIFHLMRVGGMSADEIDTLLNKRSGLFGLCG FT DNDMREIRRRVDEDDEQAGLAFDIYIHRLKKYIGAYYAVLGRVDAVAFTAGVGENSAPV FT REAAVAGLEGLGLAVDGGLNAVRGDGARLISPAGARVAVAVVPTDEEMEIATQTYALVS FT ESGNPDLT" FT misc_feature complement(213578..214741) FT /note="Pfam match to entry PF00871 Acetate_kinase, FT Acetokinase family, score 633.70, E-value 9.9e-187" FT misc_feature complement(214703..214738) FT /note="PS01075 Acetate and butyrate kinases family FT signature 1" FT CDS complement(214750..216843) FT /transl_table=11 FT /gene="SCO5425" FT /gene_synonym="pta" FT /gene_synonym="SC6A11.01c" FT /gene_synonym="SC8F4.29c" FT /product="phosphate acetyltransferase (fragment)" FT /note="SC6A11.01c, pta, phosphate acetyltransferase FT (fragment), len: >655 aa; similar to many e.g. SW:P39184 FT (PTA_ECOLI) pta, phosphate acetyltransferase from FT Escherichia coli (713 aa) fasta scores: opt: 1190, z-score: FT 1306.5, E(): 0, 37.0% identity in 687 aa overlap. Contains FT Pfam match to entry PF01515 PTA_PTB, Phosphate FT acetyl/butaryl transferase" FT /note="SC8F4.29c, partial CDS, pta, phosphate FT acetyltransferase, len: >69aa; strongly similar to the FT C-terminus of many eg. SW:P39184 (PTA_ECOLI) pta, phosphate FT acetyltransferase from Escherichia coli (713 aa) fasta FT scores; opt: 309, z-score: 427.3, E(): 2.1e-16, 78.3% FT identity in 60 aa overlap." FT /db_xref="GOA:Q8CJR5" FT /db_xref="InterPro:IPR002505" FT /db_xref="UniProtKB/TrEMBL:Q8CJR5" FT /protein_id="CAD55352.1" FT /translation="MTRSVYVTGIDRGDGRQVVELGVMELLTRQVDRVGVFRPLVHDGP FT DRLFELLRARYRLSQDPATVYGMDYQEASLLQAEQGVDELVSALVDRFHLVARDYDVVL FT VLGTDYADTQFPDELSLNARLANEFGASVLPVVGGRKQTADSVLAETHNAFRAYDGLGC FT DVLAMVTNRVAREDRDEIAERLAHRLPVPCWVVPDEPALSAPTVSQIAHALGAEIVLGD FT DSGLARDALDFVFGGAMLPNLLAALTPGCLVITPGDRADLVIGTLAAHSAGTPPIAGVL FT LTLNEVPGEGILTLAARLAPGTPVLSVTGTSFPTAERLFSLEGKLGAATPRKAETALGL FT FERYVDTAELNKRVSAPSSDRVTPMMFEHKLLEQARSDLRRVVLPEGTEERVLHAAEVL FT LRRGVCELTLLGPVEQIRKKAADLGIDLGGAELIDPAASELRDSFAEKYAALRAHKGVT FT VELAYDVVSDVNYFGTLMVQEGFADGMVSGSVHSTAATIRPAFEIIKTKPDAAIVSSVF FT FMCLADKVLVYGDCAVNPDPDAEQLADIATQSASTAAQFGVEPRIAMLSYSTGTSGSGA FT DVDKVREATELVRSRRPDLSVEGPIQYDAAVEPSVAATKLPGSAVAGQASVLIFPDLNT FT GNNTYKAVQRSAGAIAVGPVLQGLRKPVNDLSRGALVQDIVNTVAITAIQAQQSPTEKA FT SAQ" FT misc_feature complement(214882..215748) FT /note="Pfam match to entry PF01515 PTA_PTB, Phosphate FT acetyl/butaryl transferase, score 460.50, E-value 1.4e-134" FT RBS complement(216851..216854) FT RBS 216979..216983 FT CDS 216994..218019 FT /transl_table=11 FT /gene="SCO5426" FT /gene_synonym="pfkA2" FT /gene_synonym="SC6A11.02" FT /product="6-phosphofructokinase" FT /note="SC6A11.02, pfkA2, 6-phosphofructokinase, len: 341 FT aa; similar to many e.g. SW:Q59126 (PFP_AMYME) FT 6-phosphofructokinase from Amycolatopsis methanolica (352 FT aa) fasta scores; opt: 1274, z-score: 1463.6, E(): 0, 59.1% FT identity in 342 aa overlap. Also similar to TRNEW:CAB51967 FT (EMBL:AL109661) Pfk, 6-phosphofructokinase from FT Streptomyces coelicolor (342 aa) fasta scores; opt: 1251, FT z-score: 1437.4, E(): 0, 56.7% identity in 342 aa overlap. FT Contains two Pfam matches to entry PF00365 PFK, FT Phosphofructokinase and Prosite match to PS00433 FT Phosphofructokinase signature" FT /db_xref="GOA:Q9L1L8" FT /db_xref="HSSP:3PFK" FT /db_xref="InterPro:IPR015912" FT /db_xref="UniProtKB/Swiss-Prot:Q9L1L8" FT /protein_id="CAB72402.1" FT /translation="MRIGVLTAGGDCPGLNAVIRSVVHRAVDNYGDEVIGFEDGYAGLL FT DGRYRALDLNAVSGILARGGTILGSSRLERDRLREACENAGDMIQNFGIDALIPIGGEG FT TLTAARMLSDAGLPVVGVPKTIDNDISSTDRTFGFDTAVGVATEAMDRLKTTAESHQRV FT MVVEVMGRHAGWIALESGMAAGAHGICLPERPFDPADLVKMVEERFSRGKKFAVVCVAE FT GAHPAEGSMDYGKGAIDKFGHERFQGIGTALAFELERRLGKEAKPVILGHVQRGGVPTA FT YDRVLATRFGWHAVEAAHRGDFGRMTALRGTDVVMVPLAEAVTELKTVPKDRMDEAESV FT F" FT misc_feature 216997..217680 FT /note="Pfam match to entry PF00365 PFK, FT Phosphofructokinase, score 278.20, E-value 1.6e-101" FT misc_feature 217759..217893 FT /note="Pfam match to entry PF00365 PFK, FT Phosphofructokinase, score 52.20, E-value 9.9e-19" FT misc_feature 217789..217845 FT /note="PS00433 Phosphofructokinase signature" FT CDS complement(218029..218742) FT /transl_table=11 FT /gene="SCO5427" FT /gene_synonym="SC6A11.03c" FT /product="hypothetical protein SC6A11.03c" FT /note="SC6A11.03c, unknown, len: 237 aa; no significant FT database similarities" FT /db_xref="GOA:Q9L1L7" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q9L1L7" FT /protein_id="CAB72403.1" FT /translation="MWRVRRPSPGPSQSGPPFNALAARRLRAALNMGPEHVAHGIRVSY FT GLPYVSPDLVIAWERGTALPEGPELTALAGVLWCSPGELIGRPQSLREHRVARGLAPED FT VARAVGLGLPAYLRMEESDDWRGTDRQSAQLADVLGLTLPDFVTVTGREEKLADLLTSA FT VTTRWQGCVRPIAKLAPLDRRVLENVLQVLHQDYQGRMAATLSWGGGAPDSSAGGRDFL FT DRIVDHFWTAVERHP" FT CDS complement(218854..219744) FT /transl_table=11 FT /gene="SCO5428" FT /gene_synonym="SC6A11.04c" FT /product="putative integral membrane transport protein" FT /note="SC6A11.04c, possible integral membrane transport FT protein, len: 296aa; similar to many proposed transport FT proteins e.g. TR:Q9X9Y6(EMBL:AL096743) putative integral FT membrane transport protein from Streptomyces coelicolor FT (298 aa) fasta scores: opt: 515, z-score: 609.9, E(): FT 1.5e-26, 33.9% identity in 295 aa overlap. Contains Pfam FT match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, Prosite matches to PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign. and possible membrane-spanning hydrophobic FT regions" FT /db_xref="GOA:Q9L1L6" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9L1L6" FT /protein_id="CAB72404.1" FT /translation="MTDTVAPRPASRTSRAARRTTPAARRNRRRTAADAGLLVAAAAFV FT LPLAWVVLSALDPHASLRVKVPDGVTLDNFDAILTPEITFTPLLNSLILCGGATLLTVV FT CAVLAAYPLSRFRSRLNRPFLLTILFATSLPITAIMVPVYALFVRVNMIDTMQGTIFFF FT AASQLPFAIWLMKNFMDGVPKELEEAAWTDGASSFQSLLRIVLPLMGPGVAVVTVFSFV FT MMWGNFFVPFMLLLSPDQMPASVSINDFFGNRGMVAYGQLAAFSIVYSTPVVLLYVLIS FT RRLGGGFALGGAVKG" FT misc_feature complement(218989..219213) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 53.20, E-value 5.7e-12" FT misc_feature complement(219124..219210) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS complement(219746..220687) FT /transl_table=11 FT /gene="SCO5429" FT /gene_synonym="SC6A11.05c" FT /product="putative integral membrane transport protein" FT /note="SC6A11.05c, possible integral membrane transport FT protein, len: 313 aa; similar to many proposed transport FT proteins e.g. TRNEW:CAB55533(EMBL:AL117322) putative FT integral membrane transport protein from Streptomyces FT coelicolor (317 aa) fasta scores; opt: 561, z-score: 649.2, FT E(): 9.4e-29, 34.4% identity in 314 aa overlap. Contains FT Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, Prosite match to PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign. and possible membrane-spanning hydrophobic FT regions" FT /db_xref="GOA:Q9L1L5" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9L1L5" FT /protein_id="CAB72405.1" FT /translation="MTATAPEHAGPEVRKAPASPPSGTRPGTVRRSLFRALPVSPAVVL FT LLLFLAGPIVYCVVIAFTDLQLTGQAQESFVGFDNFTRAFKDEAFLNAVWLTLVFTVLS FT SLIGQNTLGLALASLMQRASKPVRTLTGGIVVTAWVLPEVVAGFLLYAFFRREGTLNAI FT LDWLHLPSQNWLFTLPILAVSFANVWRGTAFSMLVYSAALNEIPKEVTEAAEADGASGW FT RRMWHITLPMIRRSIGTNLMLNTLQTLSVFGLIWVMTRGGPSGNSQTLPLFMYEQAFQN FT SLIGYGTAVALLLLLIGSLFSVVYLRLLRTEV" FT RBS complement(219750..219755) FT misc_feature complement(219851..220084) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 66.40, E-value 6.2e-16" FT misc_feature complement(219995..220081) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS complement(220684..222060) FT /transl_table=11 FT /gene="SCO5430" FT /gene_synonym="SC6A11.06c" FT /product="putative extracellular solute-binding FT lipoprotein" FT /note="SC6A11.06c, possible extracellular solute-binding FT lipoprotein, len: 458 aa; similar to many proposed FT solute-binding proteins e.g. TR:P72397 (EMBL:Y07706) FT putative maltose-binding protein from Streptomyces FT coelicolor (423 aa) fasta scores; opt: 284, z-score: 316.1, FT E(): 3.4e-10, 29.1% identity in 443 aa overlap. Contains FT Pfam match to entry PF01547 SBP_bacterial_1, Bacterial FT extracellular solute-binding protein, Prosite match to FT PS00013 Prokaryotic membrane lipoprotein lipid attachment FT site and possible N-terminal signal sequence" FT /db_xref="GOA:Q9L1L4" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:Q9L1L4" FT /protein_id="CAB72406.1" FT /translation="MRPTVRFTALFSLTALAATSLAACSSGSGSDPDTVKVSFKQSTDN FT SIKVMDTYLGDIKKQFEKANPGKKVELVPIKAPDSEYYTKLQQMLRSPKTAPDLVYEDT FT FLINSDITSGYLKPLDDYLADWKDWDQFIDTAKAAAKGEDGKTYGVPDGTDTRGLWFSK FT DVFAKAGLPADWQPKTWDEVLDAARTIKEKVPGVTPLNVYTGKPAGEAATMQGFEMLLY FT GTGTGSGGSDPLYDKGSKKWITAGQGFEDSLSFVETVYKEKLGPEVSDALDPNFGTKVR FT GELLPQGKLGIALDGSWLPQDWLEGSGHEWPEWSKELGLAAMPTQNGQAPGRVSMSGGW FT TWAIPAKAGNPDLAFEFVKTMQTKANAQKWYVANSGISVREDVAEDPAYVDAQPGIKFF FT TDLVADTHYRPAYPAYPKVSVAIQEAMEGVTTGDKSVEEAARGYDEALKEATDNQVVSK FT " FT RBS complement(220694..220700) FT misc_feature complement(220714..221631) FT /note="Pfam match to entry PF01547 SBP_bacterial_1, FT Bacterial extracellular solute-binding protein, score FT 91.90, E-value 1.3e-23" FT misc_feature complement(221989..222021) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS complement(222068..222074) FT CDS complement(222586..223449) FT /transl_table=11 FT /gene="SCO5431" FT /gene_synonym="SC6A11.07c" FT /product="putative secreted nucleosidase" FT /note="SC6A11.07c, possible secreted nucleosidase, len: 287 FT aa; similar to many e.g. SW:P24247 (PFS_ECOLI) MTA/SAH FT nucleosidase (P46) from Escherichia coli (232 aa) fasta FT scores: opt: 211, z-score: 251.7, E(): 1.3e-06, 27.1% FT identity in 210 aa overlap. Contains Pfam match to entry FT PF01048 PNP_UDP_1, Phosphorylase family (which includes FT some nucleosidases) and possible N-terminal signal FT sequence" FT /db_xref="GOA:Q9L1L3" FT /db_xref="InterPro:IPR018017" FT /db_xref="UniProtKB/TrEMBL:Q9L1L3" FT /protein_id="CAB72407.1" FT /translation="MTMPDTQPTVLVLTALPLEYAAVRAHVEEREERVHRDGTRVEIGR FT LPDTSWHVALAELGMGAERTAALTTQLIHWLRPEAVLFVGVAGSLKDDVGIGDVVVGTQ FT VYEIHGGKQAPEGFLVRPKALPGSHALEQAARSAVRDMPRVRAHFMPIATGDVVLADAE FT SEIARFLRRNYNDAGAIEMEGSGALRAAHLNGQLNALVIRGISDRADAEKHGADASGSQ FT QRAAEQAAAVTVAVLHKHRPREGSSDSGEEPQELRARGATYGGDHIDFRGGTFHSPVTG FT KGDRRR" FT misc_feature complement(222742..223425) FT /note="Pfam match to entry PF01048 PNP_UDP_1, Phosphorylase FT family, score 18.20, E-value 8.3e-07" FT RBS complement(223455..223459) FT RBS 223464..223469 FT CDS 223477..224016 FT /transl_table=11 FT /gene="SCO5432" FT /gene_synonym="SC6A11.08" FT /product="putative integral membrane protein" FT /note="SC6A11.08, possible integral membrane protein, len: FT 179 aa; no significant database similarities. Contains FT possible membrane-spanning hydrophobic regions" FT /db_xref="UniProtKB/TrEMBL:Q9L1L2" FT /protein_id="CAB72408.1" FT /translation="MPEQDVTVGQLLLAEYESVKSEQRARIGFRDNLLYVTLAVVAAVI FT AATAQAEQPSMLLALPPVCLVLGWTYLVNDEKISAIGLYVRDDLGPKLAELAAHTSGFA FT TFGWEAYHRSDTRRRSRKTIQTVIDLTAFCAVPLAALVVFWVNGDATRLLVVLSVLEAL FT AVAGLAAQVVWYAKAA" FT CDS 224224..226509 FT /transl_table=11 FT /gene="SCO5433" FT /gene_synonym="SC6A11.09" FT /product="putative AfsR-like regulator" FT /note="SC6A11.09, possible AfsR-like regulator, len: 816 FT aa; similar to others from Streptomyces spp. e.g. SW:P25941 FT (AFSR_STRCO) regulatory protein AfsR from Streptomyces FT coelicolor (993 aa) fasta scores: opt: 490, z-score: 458.0, FT E(): 4.2e-18, 33.7% identity in 656 aa overlap. Note that FT this protein contains a Prosite match to PS00017 FT ATP/GTP-binding site motif A (P-loop) but no FT helix-turn-helix motifs" FT /db_xref="GOA:Q9L1L1" FT /db_xref="InterPro:IPR000767" FT /db_xref="UniProtKB/TrEMBL:Q9L1L1" FT /protein_id="CAB72409.1" FT /translation="MAELLAAGPSGVAGAVARAMERSAPGSGASWYGGDHTDFRDGVFL FT REVIGVQVVVQEGGTAVPEAMTGLPPRPGGFTGRDRETEDLLRALDPDGAQSAAAPVAS FT VSGLGGIGKTALAVETAHLARERGWFPGGILFIDLHGYDREPVTADRSLRTLLHALGIP FT PEHMPTTTDERAALYRSTLAVRAGERGGMLVLADNASSAEQVRPLLPGDFRHRVLVTSR FT DRLPQLGARLLPLDELGTREAYELLDRALRIADPHDGRVGDDPGTTGRLASLCGHLPLA FT LQIAAALLAADPAKPVSELVAELAEAHDRLDHLDDGERSVRAAFELSYRRLPPEQARLL FT RLLALAPGPEVSDEVVAALVGADRPPVRDQHALARAHLVERGHTRGSWRLHDLVRVFGA FT GVVARAEGDAARARVLRHYLERARAADARLKPRTEDDEGTRPFRSREEALAWFDAERAG FT LVAAVQWATDRQLAADAVRLAGALGEYLDWRRRFDDSVTVCGAVCAAARRAGDEAAEAA FT AWNRTGTALRGNRRLREAYDAHRRAHDLYDALGHDNGRAMALSNLGAILGDVGQVDDAV FT DAFRLALGLFRRTGDRHSEAGVWNNLALILRKSGRVDEALDALRSALGLYRETGDRPRE FT GRARHNYAVALNARGRTAEAVTACLDSLDICEEFEDWHGAARTLYALGLVHETAGDAER FT ARVRMTQAADAYERAGSPKEAEQARRAARLTGPAPTGTPAPAAPPDRTADSGPPGPRPP FT GVPGNAGP" FT misc_feature 224542..224565 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(226394..227086) FT /transl_table=11 FT /gene="SCO5434" FT /gene_synonym="SC6A11.10c" FT /product="putative two-component response regulator" FT /note="SC6A11.10c, possible two-component response FT regulator, len: 230 aa; similar to many e.g. SW:Q54149 FT (DPIA_ECOLI) transcriptional regulatory protein DpiA from FT Escherichia coli (226 aa) fasta scores: opt: 393, z-score: FT 440.6, E(): 3.9e-17, 33.8% identity in 222 aa overlap. FT Contains Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain and a helix-turn-helix motif FT score 1515 (+4.35 SD) in ID at residue 179" FT /db_xref="GOA:Q9L1L0" FT /db_xref="HSSP:1UDR" FT /db_xref="InterPro:IPR001789" FT /db_xref="UniProtKB/TrEMBL:Q9L1L0" FT /protein_id="CAB72410.1" FT /translation="MSTADSQPIRVLVVEDDPVAADAHVMYVGRVPGFVAVGKAHTGAE FT ARRMLDRTPVDLLLLDLHLPDVHGLQLARSLRAAGHHTDVIAVTSARDLTMVREGVSLG FT VVQYVLKPFTFATLRDRLVRYAEFRGTAGEASGQDEVDRALATLRAPGPAALPKGLSGP FT TLERVTGALRGATEGLTAAGVAEAVGISRITARRYLEHLVDAGRAGRSPQYGQVGRPEL FT VYRWVRGR" FT misc_feature complement(226721..227062) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 94.90, E-value 1.6e-24" FT CDS complement(227083..228741) FT /transl_table=11 FT /gene="SCO5435" FT /gene_synonym="SC6A11.11c" FT /product="putative two-component sensor kinase" FT /note="SC6A11.11c, possible two-component sensor kinase, FT len: 552 aa; similar to many eg. SW:P39272 (DCUS_ECOLI) FT sensor protein DcuS from Escherichia coli (543 aa) fasta FT scores; opt: 764, z-score: 809.1, E(): 0, 29.3% identity FT in 540 aa overlap. Contains Pfam match to entry PF00512 FT signal, Histidine kinase and possible membrane-spanning FT hydrophobic regions" FT /db_xref="GOA:Q9L1K9" FT /db_xref="HSSP:1JM6" FT /db_xref="InterPro:IPR013656" FT /db_xref="UniProtKB/TrEMBL:Q9L1K9" FT /protein_id="CAB72411.1" FT /translation="MHLRVPRPRSLAGQLFAMQAVLIAVVVVGYALFSYISDRGQAEEA FT AGRQARAVSLAIADSPSVAEAIRTPDPTALLQPYAVRVMRDTDVDFVTIMNPEGIRWTH FT PEPTEIGHLFQGHIERAQRGQTFTETYTGTLGPSVRAVTPIVDDGRIVGLVSAGIKVEE FT ISKRAQEQLTALSGVAAGALLLGAVGTYVINARLRRHTHGMNADELSRMHDYHQAALHA FT VREGLLMLDGQYRVALINDGGRELLGVRGDVVGASVADLGLPSQLTGALLASEPRVDEV FT HLAAERVLVVNTSPVSGGERRGTVVTLRDVTELQSLTGELNSERGFTQALRSQAHEAAN FT RLHTVVSLIELGRAEEAVEFATAELELAQALTDQVVAAVSEPVLAALLLGKTAQANERG FT VELVVSQDSRLDDGLLPPSLPARDLVTILGNLVDNAVDATQGAVPSRVTVAAYTEASGA FT GGSELVLRVSDTGAGVDPAHADLVFQRGYSTKPAGEGGRGLGLALVRQAVRRHGGALTV FT TEAEGGGARFEARLPLGDGAAPAAAAGRPGAGGAL" FT RBS complement(227092..227097) FT misc_feature complement(227146..227781) FT /note="Pfam match to entry PF00512 signal, Histidine FT kinase, score 61.60, E-value 1.7e-14" FT RBS complement(228751..228756) FT RBS 228883..228889 FT CDS 228896..230296 FT /transl_table=11 FT /gene="SCO5436" FT /gene_synonym="SC6A11.12" FT /product="putative sodium:dicarboxylate symporter" FT /note="SC6A11.12, possible sodium:dicarboxylate symporter, FT len: 466 aa; similar to many e.g. SW:P50334 (DCTA_SALTY) FT C4-dicarboxylate transport protein from Salmonella FT typhimurium (428 aa) fasta scores: opt: 1320, z-score: FT 1451.6, E(): 0, 48.9% identity in 419 aa overlap. Contains FT Pfam match to entry PF00375 SDF, Sodium:dicarboxylate FT symporter family" FT /db_xref="GOA:Q9L1K8" FT /db_xref="InterPro:IPR001991" FT /db_xref="UniProtKB/TrEMBL:Q9L1K8" FT /protein_id="CAB72412.1" FT /translation="MTSEAATAPAAPKAKRDRTHYLYIAVIIAVALGIAVGLAAPDFAT FT ELKPLGTGFVNLIKMMISPIIFCTIVLGIGSVRKAAKVGAVGGIALGYFLVMSLVALAI FT GLIVGNILDPGTGLAVTDAVKETGQAQVDAEAKGTVDFLMGIIPTTIVSAFTAGEVLQT FT LLIALLCGFALQAMGNAGQPVLRGIEHIQRLVFRVLAMIMWAAPVGAFGAIAAVTGSAG FT VDALKSLAVLMLGFYATCVIFLFVVLGTVLRVVAGINVFSLFKYLGREFLLILSTSSSE FT SALPRLIAKMEHLGISKPVVGITVPTGYSFNLDGTMIYMTMASLFISDAMGTPMSIGEQ FT IPLLLFLLVASKGAAGVSGAGLATLAGGLQSHKPALVDGIGLIVGIDRFMSEARALTNF FT GGNAVATVLIGTWTKEIDKDRVNEVLAGRAPFDEKTLLDDGHGPADGDGAGAPDLPEQG FT GEKELAKA" FT misc_feature 228959..230131 FT /note="Pfam match to entry PF00375 SDF, FT Sodium:dicarboxylate symporter family, score 350.60, FT E-value 1.7e-101" FT CDS 230460..230858 FT /transl_table=11 FT /gene="SCO5437" FT /gene_synonym="SC6A11.13" FT /product="putative MerR-family transcriptional regulator" FT /note="SC6A11.13, possible MerR-family transcriptional FT regulator, len: 132 aa; similar to many e.g. TR:Q9X5V4 FT (EMBL:AF127795) heavy metal regulator HmrR from Rhizobium FT leguminosarum (biovar viciae) (129 aa) fasta scores; opt: FT 228, z-score: 295.1, E(): 5e-09, 35.7% identity in 129 aa FT overlap. Contains Pfam match to entry PF00376 merR, FT Bacterial regulatory proteins, merR family and possible FT helix-turn-helix motif score 1747 (+5.14 SD) in ID at FT residue 1" FT /db_xref="GOA:Q9L1K7" FT /db_xref="HSSP:1Q06" FT /db_xref="InterPro:IPR015358" FT /db_xref="UniProtKB/TrEMBL:Q9L1K7" FT /protein_id="CAB72413.1" FT /translation="MRIGELAARAGTTTRTLRYYESRGLLPARRGGNGYRTYDEDDLKL FT LRQIRTLQDFGFDLEETRPFVECLRAGHPEGDSCPASLVVYRRKLAELDTLIEQLTSVR FT AQVAAQLTRAEAAAPGGPEPKCELGGHG" FT misc_feature 230469..230573 FT /note="Pfam match to entry PF00376 merR, Bacterial FT regulatory proteins, merR family, score 37.40, E-value FT 3.2e-07" FT misc_feature 230870..231181 FT /note="Pfam match to entry PF00085 thiored, Thioredoxin, FT score 97.20, E-value 5.4e-28" FT CDS 230870..231184 FT /transl_table=11 FT /gene="SCO5438" FT /gene_synonym="trxA2" FT /gene_synonym="SC6A11.14" FT /product="thioredoxin" FT /note="SC6A11.14, trxA2, thioredoxin, len: 104 aa; similar FT to many e.g. SW:P52230 (THIO_STRCO) thioredoxin TrxA from FT Streptomyces coelicolor (110 aa) fasta scores: opt: 360, FT z-score: 470.8, E(): 8.2e-19, 47.5% identity in 101 aa FT overlap. Contains Pfam match to entry PF00085 thiored, FT Thioredoxin and Prosite match to PS00194 Thioredoxin family FT active site" FT /db_xref="GOA:Q9L1K6" FT /db_xref="HSSP:1NSW" FT /db_xref="InterPro:IPR013766" FT /db_xref="UniProtKB/TrEMBL:Q9L1K6" FT /protein_id="CAB72414.1" FT /translation="MPEVTDADFAAEVIGSELPVLVEFTADWCPPCRQMAPVLSALAEE FT EGDRFRVVQLNVDQNPATTNAYKVLSMPTFMVFRGGEPVKSMVGSRPKRRLLEELADVV FT " FT misc_feature 230930..230986 FT /note="PS00194 Thioredoxin family active site" FT RBS 231306..231311 FT CDS 231320..233587 FT /transl_table=11 FT /gene="SCO5439" FT /gene_synonym="SC6A11.15" FT /product="conserved hypothetical protein SC6A11.15" FT /note="SC6A11.15, hypothetical protein, len: 755 aa; FT similar to TR:O32215 (EMBL:Z99121) hypothetical protein FT from Bacillus subtilis (774 aa) fasta scores: opt: 323, FT z-score: 361.2, E(): 1e-12, 23.5% identity in 763 aa FT overlap" FT /db_xref="GOA:Q9L1K5" FT /db_xref="InterPro:IPR014016" FT /db_xref="UniProtKB/TrEMBL:Q9L1K5" FT /protein_id="CAB72415.1" FT /translation="MRPGVELSNTEFPDDELLHEQEFIDGLYARVDALRGDAEDSVTDA FT LAQGNTPQQARLERDILVAERSGLLAALNAVDGSLCFGRIDLTSGQGHHIGRIGLRADD FT AERTPVLIDWRAGVARPFYLATGHTPMGLRRRRHITSEGRTVTALHDEILDLGDERRTG FT HEDPSGDAVLLAALNSARTGRMGDIVQTIQADQDRIIRAPHRGVLVVEGGPGTGKTAVA FT LHRAAYLLYEHRELLAKRAVLIVGPNPAFLGYIGEVLPSLGETGVLLATVGELFPGVKA FT TATDTPEAAAVKGRAEMADVLAEAVRARQALPDPVIAIEHDRDILMLDDDLVNVARERT FT RAAKLPHNAAREHFEGHILNTLTDMVAERIGTDPYDGSNLLDPSDITQIRDELAENPEV FT WSAVDRLWPRLTPQRLVADLLAAPESFLPAEDAAAVRRPVTRRWTVADVPLLDEAAELL FT GVDDRIARSRAEREREEQIAYAQGVLDVSYASRTYEFEDKDEEDAEVLSAHDIIDAERF FT AERQEEDDHRSAAERAAADRTWAFGHIIVDEAQELSPMAWRLLMRRCPTRSMTLVGDPA FT QTAEAAGVGSWSKILAPYVEDRWEHTRLGVNYRTPAEVMDLAAAVVRADDPEFTPPSSV FT RSTGARPWVRATGDLPAAVAEAVRELTPEEGRLAVIAPRELHRVLAARLDGVTADAEPD FT LTHRVVLLDPRQSKGLEFDSVLVVEPGRYGTSDLYVALTRATQHLGVLHSEPLPKGLED FT AG" FT misc_feature complement(233566..236062) FT /note="Region previously sequenced as EMBL:X83397" FT CDS complement(233645..235969) FT /transl_table=11 FT /gene="SCO5440" FT /gene_synonym="glgBI" FT /gene_synonym="SC6A11.16c" FT /product="1,4-alpha-glucan branching enzyme" FT /note="SC6A11.16c, glgBI, 1,4-alpha-glucan branching FT enzyme, len: 774 aa; previously sequenced and characterised FT as TR:Q59833 (EMBL:X83397). Also strongly similar to many FT others e.g. SW:P07762 (GLGB_ECOLI) 1,4-alpha-glucan FT branching enzyme from Escherichia coli (728 aa) fasta FT scores: opt: 2149, z-score: 2347.4, E(): 0, 50.5% identity FT in 711 aa overlap. Contains Pfam match to entry PF00128 FT alpha-amylase, Alpha amylase" FT /db_xref="GOA:Q59833" FT /db_xref="HSSP:1M7X" FT /db_xref="InterPro:IPR013783" FT /db_xref="UniProtKB/Swiss-Prot:Q59833" FT /protein_id="CAB72416.1" FT /translation="MTPRPSSSGPDPRKTTGKKPAGKTPTGKKPAKAAKKKAPRRTTAS FT ANASATTSVSGAEVAVSPAPDAADRERLLAGTHHDPHAVLGAHRVPGGVAFRVFRPYAL FT AVTVLSGELRVGLHDDGDGFFSGLVPLKDVPAHRLLVAYEGTEQEVEDPYRFLPTLGEL FT DLHLLGEGRHEQLWRALGAHPTTHEGVAGTRFAVWAPNARGVRVAGGFNFWDGTGHPMR FT SLGSTGVWELFLPGVGAGELYKFEITRPDGSRTFRADPLARRTEVPPATSSVVHASDYT FT WGDEEWLAHRADAPAHEAPMSVYEVHLPSWRPGLTYRQLAEQLPAYVADLGFTHVELMP FT VAEHPFGGSWGYQVTGFYAPTARLGDPDDFKYLVDRLHRAGIGVLMDWVPAHFPRDDWA FT LAEFDGRPLYEHSDPLRAAHPDWGTLEFDFGRREVRNFLVANAVYWCEEFHIDGLRVDA FT VASMLYLDYSREPGEWEPNEHGGRENLDAVAFLQEMNATLYRRVPGVVTVAEESTAWDG FT VTRATHHEGPSGFGGLGFGLKWNMGWMHDSLDYMSHEPVHRKHHHGEMTFSMVYAYSEN FT YVLPISHDEVVHGKRSLVSKMPGDWWQQRANERAYLGFMWAHPGKQLLFMGQEFAQGAE FT WSEAHGPDWWLLDPEYGASADHRGVRDLVRDLNTVYRATPALWRRDTHPSGFSWVVGDA FT AEDNVLAFLRLDADGTPLLAVSNFAPVVRSGYRLGVPDEVPAWHEVLNTDAARYGGGDV FT VNPDPVKPEPQGGTAARRASG" FT misc_feature complement(233912..235066) FT /note="Pfam match to entry PF00128 alpha-amylase, Alpha FT amylase, score -40.10, E-value 2.2e-05" FT misc_feature complement(235319..243628) FT /note="Region previously sequenced as EMBL:AJ001205." FT RBS complement(235978..235983) FT CDS complement(236010..237404) FT /transl_table=11 FT /gene="SCO5441" FT /gene_synonym="pep2A" FT /gene_synonym="SC6A11.17c" FT /product="hypothetical protein" FT /note="SC6A11.17c, pep2A, hypothetical protein, len: 464 FT aa; previously sequenced as TR:O54204 (EMBL:AJ001205)" FT /db_xref="InterPro:IPR002575" FT /db_xref="UniProtKB/TrEMBL:O54204" FT /protein_id="CAB72417.1" FT /translation="MPEAVIRTDTSPPGLLASLDPLLREWLPRQRWFAGKGRPVTGFSL FT VAATELLPADSRLGLHHVLVRAHQRHTPAGGGAQEPGDCYQLLIGTREALPPRLAPALI FT GHVTEGPAAGRTAYDALYDTRPAEVLLEALRTRARIGGLRFERAPDDVIRAGLVPRLMT FT AEQSNSSVVYGDTFILKVLRRIVPGVNPDLELPLALAREGCPRVPAPAGWMVADLAGRT FT WVLGVLQPYLQGATDGWELALRELAKGEDFAAEARALGRATAEVHTALARALPTVTLGH FT AQARQLADGMTERLEAAARAVPLLRSYAPGLRTAFTALADLASEGRAWSAQRVHGDLHL FT GQCLRSPDGEWSLIDFEGEPAKPLAERRLPQPAVRDVAGMLRSFDYAAHSADVRVPGWA FT ESCRAAYCTGYAEAGGHDPRTDPVLLRAYETDKAVYEVLYEARHRPEWLEVPLAAVRRL FT SVPEPA" FT CDS complement(237425..239125) FT /transl_table=11 FT /gene="SCO5442" FT /gene_synonym="SC6A11.18c" FT /product="putative trehalose synthase" FT /note="SC6A11.18c, possible trehalose synthase, len: 566 FT aa; previously sequenced as TR:O54203 (EMBL:AJ001205) FT Streptomyces coelicolor putative trehalose synthase. Also FT similar to many others e.g. SW:Q99040 (DEXB_STRMU) glucan FT 1,6-alpha-glucosidase DexB from Streptococcus mutans (536 FT aa) fasta scores: opt: 867, z-score: 1015.8, E(): 0, 32.2% FT identity in 522 aa overlap. Contains Pfam match to entry FT PF00128 alpha-amylase, Alpha amylase" FT /db_xref="GOA:Q9L1K3" FT /db_xref="HSSP:1M53" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:Q9L1K3" FT /protein_id="CAB72418.1" FT /translation="MIVNEPVPDTFEDTPAKDRDPDWFKRAVFYEVLVRSFQDSNGDGI FT GDLKGLTAKLDYLQWLGVDCLWLPPFFKSPLRDGGYDVSDYTAVLPEFGDLADFVEFVD FT AAHQRGMRVIIDFVMNHTSDQHPWFQESRRNPDGPYGDYYVWADDDKQFQDARIIFVDT FT EASNWTYDPVRKQYYWHRFFSHQPDLNYENPVVQEEMISALKFWLDLGIDGFRLDAVPY FT LYQEEGTNCENLPRTHDFLKRVRKEIDAQYPDTVVLAEANQWPEDVVDYFGDYAAGGDE FT CHMAFHFPVMPRIFMAVRRESRYPVSEILAKTPAIPSGCQWGIFLRNHDELTLEMVTDE FT ERDYMYAEYAKDPRMRANIGIRRRLAPLLDNDRNQIELFTALLLSLPGSPILYYGDEIG FT MGDNIWLGDRDAVRTPMQWTPDRNAGFSSSDPGRLFLPTIMDPVHGYQVTNVEASMASP FT SSLLHWTRRMIEIRKQNVAFGLGTYTELPSSNPAVLAFLREHEDDLVLCVHNFSRFAQP FT TELDLSAFDGRHPVELFGGVRFPAVGDLPYLLTLGGHGFYWFRLRKDAA" FT misc_feature complement(237695..239044) FT /note="Pfam match to entry PF00128 alpha-amylase, Alpha FT amylase, score 279.90, E-value 3.2e-80" FT CDS complement(239122..241149) FT /transl_table=11 FT /gene="SCO5443" FT /gene_synonym="pep1A" FT /product="putative alpha-amylase" FT /note="SC6A11.19c, pep1A, possible alpha-amylase, len: 675 FT aa; previously sequenced as TR:O54202 (EMBL:AJ001205). Also FT similar to TRNEW:AAF07898 (EMBL:AF172946) putative FT glucanase GlgE from Mycobacterium smegmatis (697 aa) fasta FT scores; opt: 2199, z-score: 2484.5, E(): 0, 53.6% identity FT in 679 aa overlap. Contains Pfam match to entry PF00128 FT alpha-amylase, Alpha amylase" FT /db_xref="GOA:Q9L1K2" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/Swiss-Prot:Q9L1K2" FT /protein_id="CAB72419.1" FT /translation="MPATHHSSATSAERPTVVGRIPVLDVRPVVQRGRRPAKAVTGESF FT EVSATVFREGHDAVGANVVLRDPRGRPGPWTPMRELAPGTDRWGATVTAGETGTWSYTV FT EAWGDPVTTWRHHARIKIPAGLDTDLVLEEGARLYERAAADVPGREDRRELLAAVDALR FT DESRPAASRLAAALTPQVDAVLARHPLRDLVTSSDPLPLLVERERALYGAWYEFFPRSE FT GTPHTPHGTFRTAARRLPAIAAMGFDVVYLPPIHPIGTTHRKGRNNTLSATGDDVGVPW FT AIGSPEGGHDSIHPALGTLDDFDHFVTEAGKLGLEIALDFALQCSPDHPWVHKHPEWFH FT HRPDGTIAHAENPPKKYQDIYPIAFDADPDGLATETVRILRHWMDHGVRIFRVDNPHTK FT PVAFWERVIADINGTDPDVIFLAEAFTRPAMMATLAQIGFQQSYTYFTWRNTKQELTEY FT LTELSGEAASYMRPNFFANTPDILHAYLQHGGRPAFEVRAVLAATLSPTWGIYSGYELC FT ENTPLREGSEEYLDSEKYQLKPRDWTRAAREGTTIAPLVTRLNTIRRENPALRQLRDLH FT FHPTDKEEVIAYSKRQGSNTVLVVVNLDPRHTQEATVSLDMPQLGLDWHESVPVRDELT FT GETYHWGRANYVRLEPGRTPAHVCTVLRPSHPQIGGSHTT" FT RBS complement(239138..239142) FT misc_feature complement(239284..240513) FT /note="Pfam match to entry PF00128 alpha-amylase, Alpha FT amylase, score -81.50, E-value 0.0017" FT RBS complement(241155..241159) FT RBS 241503..241507 FT CDS 241514..244138 FT /transl_table=11 FT /gene="SCO5444" FT /gene_synonym="SC3D11.01" FT /gene_synonym="glgP" FT /gene_synonym="SC6A11.20" FT /product="putative glycogen phosphorylase" FT /note="SC3D11.01, glgP, possible glycogen phosphorylase, FT len: >201aa; previously sequenced as TR:O70011 FT (EMBL:AJ001205). Also similar to TR:Q9YGA7 (EMBL:AF115479) FT maltodextrin phosphorylase from Thermococcus litoralis (831 FT aa) fasta scores; opt: 242, z-score: 283.2, E(): 2.3e-08, FT 30.9% identity in 194 aa overlap." FT /note="SC6A11.20, glgP, possible glycogen phosphorylase FT (fragment), len: >705 aa; previously sequenced as TR:O70011 FT (EMBL:AJ001205). Also similar to TR:Q9YGA7 (EMBL:AF115479) FT maltodextrin phosphorylase from Thermococcus litoralis (831 FT aa) fasta scores; opt: 849, z-score: 972.3, E(): 0, 40.5% FT identity in 699 aa overlap. Contains Prosite match to FT PS00102 Phosphorylase pyridoxal-phosphate attachment site" FT /db_xref="GOA:Q8CJR4" FT /db_xref="InterPro:IPR000811" FT /db_xref="UniProtKB/TrEMBL:Q8CJR4" FT /protein_id="CAD55353.1" FT /translation="MRVKAIRRLTVRPVLPDPLRPLSDLARNLRWSWHPETRDLFHSVD FT PECWTASGGDPVRLLGTVRPARLAELAEDRRFLRRLTAVAYDLDHYMTGDRWYQAQSGR FT LPAAVAYFSPEFGITAALPQYSGGLGILAGDHLKAASDLGVPLVGVGLLYRHGYFRQSL FT SRDGWQQEHYPVLDPHELPLAPLKERDGTPAHVALALPGGRELRARVWLAQVGRVPLLL FT LDSDVEENDPGERGVTDRLYGGGSEHRLLQEMLLGIGGVRAVRTYCRITGHPAPEVFHT FT NEGHAGFLGLERIAELCDAGSDFGSALEAVRAGTVFTTHTPVPAGIDRFDRELVARHFG FT PDAELPRIEVERVLRLGMETYPGGEPNLFNMAVMGLRLAQRANGVSVLHGGVSRGMFAG FT LWPGFDADEVPITSVTNGVHAPTWVAPEVFRLGARQIGVQRAEDALAVGGSDRWDSVAD FT IPDRDIWELRRTLRAQLVEEVRERLRASWRQRGAGTAELGWIDDALDPDVLTIGFARRV FT PSYKRLTLMLRDRERLTELLLHPERPIQIVVAGKAHPADDGGKRLVQELVRFADDARVR FT HRIVFLPDYGMAMAQKLYPGCDIWLNNPLRPLEACGTSGMKAALNGCLNLSVLDGWWDE FT WYQPDFGWAIPTADGAGTDPDRRDAIEADALYDLLEQRITPRFYERGASGLPDRWLEMV FT RRTLSLLGPKVLAGRMVREYVERLYTPAAEAHRAMDPDSARGLAEWKARVRAAWPGVSV FT DHVETSAATASAELGTTLALRVRVKLGDLAPEDVEVQAVSGRVDSEDRITDAARTSLKP FT VGGPDLEGRWAYEGPLALDRTGPFGYTVRVLPAHRLLASGVETGLVAVPSGDLVEAAGL FT LMR" FT misc_feature 243338..243376 FT /note="PS00102 Phosphorylase pyridoxal-phosphate attachment FT site" FT misc_feature complement(243532..244906) FT /note="Region previously sequenced as EMBL:AJ001205 FT Streptomyces coelicolor A3(2) glycogen metabolism clusterI" FT stem_loop 244159..244207 FT /note="Inverted repeat with 1 base loop, Score 51: 21/24 ( FT 87%) matches, 0 gaps" FT CDS complement(244182..244748) FT /transl_table=11 FT /gene="SCO5445" FT /gene_synonym="SC3D11.02c" FT /product="conserved hypothetical protein" FT /note="SC3D11.02c, hypothetical protein, len: 188aa; FT previously sequenced as TR:Q9X945 (EMBL:AJ001205) and FT predicted as a 134 aa protein. Also similar to TR:O06198 FT (EMBL:Z95387) hypothetical protein from Mycobacterium FT tuberculosis (166 aa) fasta scores; opt: 407, z-score: FT 496.4, E(): 3.1e-20, 44.0% identity in 159 aa overlap" FT /db_xref="InterPro:IPR018960" FT /db_xref="UniProtKB/TrEMBL:Q9L1G0" FT /protein_id="CAB75999.1" FT /translation="MTGGTRNQRFPGAALPLVPMSFTYDDVGATREQGACPPGFRPMHV FT RTRLGEGEPVFRRAAEAVLTWEMHREMGVGIEAGAERAAPGVDVTVTLAGLIKAPCRVV FT WTLEEPRRAGWAYGTLPGHPESGEEAFVVDRTGDGTVWLTVHAFSRPATWYAKAGGPAA FT RAFQHAYARRCGTVLRRLSGGDEQD" FT CDS complement(244761..246410) FT /transl_table=11 FT /gene="SCO5446" FT /gene_synonym="SC3D11.03c" FT /note="SC3D11.03c, probable neutral zinc metalloprotease, FT len: 549aa; similar to many eg. SW:P05806 (NPRE_BACCE) FT bacillolysin precursor (EC 3.4.24.28) from Bacillus cereus FT (566 aa) fasta scores; opt: 607, z-score: 636.5, E(): FT 4.8e-28, 34.7% identity in 596 aa overlap. Also similar to FT the neighbouring CDS SC3D11.04c fasta scores; opt: 2442, FT z-score: 2158.9, E(): 0, 69.7% identity in 544 aa overlap FT and TR:CAB69762 (EMBL:AL137187) putative metalloproteinase FT from Streptomyces coelicolor fasta scores; opt: 1290, FT z-score: 1143.7, E(): 0, 52.7% identity in 560 aa overlap. FT Contains Pfam match to entry PF01447 Peptidase_M4, FT Thermolysin family peptidase and Prosite match to PS00142 FT Neutral zinc metallopeptidases, zinc-binding region FT signature. Contains possible hydrophobic membrane spanning FT region" FT /db_xref="GOA:Q9L1F9" FT /db_xref="HSSP:1NPC" FT /db_xref="InterPro:IPR006025" FT /db_xref="UniProtKB/TrEMBL:Q9L1F9" FT /protein_id="CAB76000.1" FT /translation="MSSLFACHKRTTLALATAVAAGAMLTTGLTAGNAAADSAAPSALP FT GAPVLLSGSARSALIQEQQAGAAGTAREMGLGAKEKLVVKDVVKDRDGSVHTRYERTYD FT GLPVLGGDLVVHRSESGATRGVTKATEAAVKVATVTPKVKAAKAEQQALSAAKDAGSSK FT TAADSAPRKVIWAAQGKPVLAYETVVGGLQDDGTPNELHVITDADTGAKLYEYQGIETG FT SGKSLYSGTVELGTTRSGSSYQLYDTGRGGHKTYNLARKTSGTGTLFTDADDTWGTGAA FT SSDPQDQTAAVDAAYGAQVTWDFYKESFGRSGIKNDGKAAYSRVHYGSNYVNAFWSDSC FT FCMTYGDGTGNTNPLTSLDVAGHEMSHGVTSNTAGLNYSGESGGLNEATSDIFGTGVEY FT FANSSADKGDYLIGERIDINGDGTPLRYMDEPSKDGASKDYWDSGLGGVDVHYSSGPAN FT HFFFLLSEGSGARTVDGVDYDSPTSDGSTVTGIGRDKALQIWYKALTEYMTSTTDYADA FT RTATLSAASDLYGADSTEYKTVGASWTAINVS" FT misc_feature complement(244770..245759) FT /note="Pfam match to entry PF01447 Peptidase_M4, FT Thermolysin family peptidase, score 270.20, E-value FT 2.8e-77" FT repeat_region complement(244786..246196) FT /note="Relevant to similarity between SC3D11.03c and FT SC3D11.04c" FT misc_feature complement(245304..245333) FT /note="PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature" FT RBS complement(246414..246421) FT stem_loop complement(246661..246703) FT /note="Inverted repeat with 7 base loop, Score 54: 18/18 FT (100%) matches, 0 gaps" FT CDS complement(246738..248792) FT /transl_table=11 FT /gene="SCO5447" FT /gene_synonym="SC3D11.04c" FT /product="putative neutral zinc metalloprotease" FT /note="SC3D11.04c, probable neutral zinc metalloprotease, FT len: 684aa; similar to many eg. SW:P43263 (NPRE_BACBR) FT bacillolysin precursor from Bacillus brevis (527 aa) fasta FT scores; opt: 648, z-score: 662.4, E(): 1.7e-29, 34.6% FT identity in 480 aa overlap. Also similar to the FT neighbouring CDS SC3D11.03c fasta scores; opt: 2442, FT z-score: 2055.1, E(): 0, 69.9% identity in 544 aa overlap FT and TR:CAB69762 (EMBL:AL137187) putative metalloproteinase FT from Streptomyces coelicolor fasta scores; opt: 1265, FT z-score: 1067.4, E(): 0, 50.2% identity in 560 aa overlap. FT Contains Pfam match to entry PF01447 Peptidase_M4, FT Thermolysin family peptidase and Prosite match to PS00142 FT Neutral zinc metallopeptidases, zinc-binding region FT signature. Contains possible hydrophobic membrane spanning FT region" FT /db_xref="GOA:Q9L1F8" FT /db_xref="HSSP:1NPC" FT /db_xref="InterPro:IPR006025" FT /db_xref="UniProtKB/TrEMBL:Q9L1F8" FT /protein_id="CAB76001.1" FT /translation="MLSSSTPHRRTSHTTSHTSRRTAHRRAAAVALAGVAALIATAVQS FT GTATAAPDPSPAKGNELVRLSPAQRAELIRDADATKAKTAGELGLGAKEKLVVRDVAKD FT RDGTLHTRYERTYDGLPVLGGDLVVATDAGKTEQVVKATAKALRPATVTPKISAAKAES FT QAVSAAKAAGAEQPDADRAPRKVIWAASGTPVLAYETVVGGLQEDGTPNELHVITDAAT FT GAKLYEYQGIENGTGNTLYSGTVTLGTAQSGSSYTLTDTARGNHKTYNLNRGTSGTGTL FT FSGSDDVWGNGSASNAETAAADAHYGAALTWDYYKNVHGRSGIRGDGVGAYSRVHYGNN FT YVNAFWQDSCFCMTYGDGSGNANPLTSIDVAAHEMSHGVTSVTAGLNYSGESGGLNEAT FT SDIFATAVEFYANNSSDVGDYLIGEEIDINGDGTPLRYMDKPSKDGASKDSWYSGIGGV FT DVHYSSGPANHFFYLLSEGSGTKTINGVTYNSPTSDGLPVTGIGRAKAEKIWFRALTTK FT FTSTTNYAGARTGTLAAAGELYGTDSAEYTAVANAWAGINVGARPGGGDPGDGTTFEST FT TNVNIPDYGSAVTSSLTVSGRTGNAPSNLQVGVDIEHTWRGDLQIDLVAPDGSTYRLKN FT SGYDPAEDVHETYTVNASSESANGTWKLRVQDQGPADTGYIDAWRLTFP" FT misc_feature complement(247116..248102) FT /note="Pfam match to entry PF01447 Peptidase_M4, FT Thermolysin family peptidase, score 259.50, E-value FT 4.4e-74" FT repeat_region complement(247136..248536) FT /note="Relevant to similarity between SC3D11.03c and FT SC3D11.04c" FT misc_feature complement(247656..247685) FT /note="PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature" FT RBS complement(248798..248803) FT CDS complement(249084..250835) FT /transl_table=11 FT /gene="SCO5448" FT /gene_synonym="SC3D11.05c" FT /product="putative ABC transporter" FT /note="SC3D11.05c, probable ABC transporter, len: 583aa; FT similar to many eg. TR:Q54204 (EMBL:X89010) from the FT 5'-hydroxystreptomycin production/transport operon of FT Streptomyces glaucescens (591 aa) fasta scores; opt: 1687, FT z-score: 1814.2, E(): 0, 49.3% identity in 564 aa overlap. FT Contains Pfam match to entry PF00005 ABC_tran, ABC FT transporter, Pfam match to entry PF00664 ABC_membrane, ABC FT transporter transmembrane region and Prosite match to FT PS00017 ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q9L1F7" FT /db_xref="HSSP:1MV5" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9L1F7" FT /protein_id="CAB76002.1" FT /translation="MTQLPVAEGADVRRAAAGLVRTDRRSFAVVLGLNALAALAGLAGP FT WLLGRIVDEVRGGGGVGAVDRMALAILLCSLAQLLLARWARYVGHRFGERTLARVRERY FT VERALALPASVVERAGSGDLTTRGTADVTAVGTTLRDAGPELLVNAVQALFLTAAVFVL FT DPLLGLAGVLGLTPAWIALRWYLRRARAAYLAEGAANSDVAESLAATVAGARTVEAFGL FT AERRVATNRGALEVSLRTRLRTLFLRSVFFPAVDISYVLPVAGVLLLGGVLHAHGSASL FT GAVVSCAVYLQQLAGPLDEVLMRVEQLQAGAASFARVEGLARAPRATADEAAVPDGDRI FT DVSGVRYAYDRGGEVLRGVDLTVRPGERLAVVGPSGAGKTTLSRLLAGVDAPTEGSVTV FT GGVPVVALGPERLRRQVVLVTQEHHVFLGTVRDNLLIAEPGAADEELWAALAAVGAEGW FT VRELPGGLGAELGAKGHSPDGSQAQQLALARVVLADPHTLILDEATALLDPTTARHTEQ FT ALAAVLKGRTVIAIAHRLHTAHDADRVAVMEDGLLTELGTHDELVAAGGAYAALWGSWH FT GEPSAGY" FT misc_feature complement(249186..249740) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 146.30, E-value 5.4e-40" FT misc_feature complement(249696..249719) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(249942..250757) FT /note="Pfam match to entry PF00664 ABC_membrane, ABC FT transporter transmembrane region., score 66.90, E-value FT 4.2e-16" FT CDS complement(250832..252649) FT /transl_table=11 FT /gene="SCO5449" FT /gene_synonym="SC3D11.06c" FT /product="putative ABC transporter" FT /note="SC3D11.06c, probable ABC transporter, len: 605aa; FT similar to many eg. TR:Q54203 (EMBL:X89010) from the FT 5'-hydroxystreptomycin production/transport operon of FT Streptomyces glaucescens (584 aa) fasta scores; opt: 885, FT z-score: 878.4, E(): 0, 40.3% identity in 601 aa overlap. FT Contains Pfam match to entry PF00005 ABC_tran, ABC FT transporter, Pfam match to entry PF00664 ABC_membrane, ABC FT transporter transmembrane region and Prosite match to FT PS00211 ABC transporters family signature." FT /db_xref="GOA:Q9L1F6" FT /db_xref="InterPro:IPR001140" FT /db_xref="UniProtKB/TrEMBL:Q9L1F6" FT /protein_id="CAB76003.1" FT /translation="MRIDAYEDPGAPDRRGGWRYLAWLVRRQWPRCLAGAVLASVWMVL FT LAATPYLMARAVDHGLEPGDLGALAGWTGAMVAVGGVNAWLGMMRHRTMTKVRMDANFR FT TVKVVVGHATRLGAALRGQVGTGEVVTIGVGDVQTISTSLTAVGPGVGAVVAYAAVGGL FT MLSVSPRLALVVLLGVPALGVLLGPLMGRLQGREAEYRERQSVLTARIGDLAGGLRVLN FT GLGGKGLVADAFRRDSGRLREQGYRVGAVTSWIQALGVGLPVLFLALVTWLGARQAAQG FT HISVGELVSVYGYVVALGWPVAFLIEMGHQLSRGVVAARRVVAFLGLEPAPDEGTRDAP FT AEPSVLYDPASGVRITPGRLTALVTAHPSDATGILDRLGRYTPSDATWGDIPLAEIPLT FT QVRARILVADPEADLFAGTLSAVIGVPDTDPRGAGNCATSHNAPAPAPAPGQQPTGADE FT APHLTAAINAAAAEDIVRALPDGLKTQVAAQARDLSGGQRQRIRLARALLTDPEVLLAA FT EPTSALDAHTEATVADRLRAARQGRTTVLAATSPLLLDRADVVHHLVDGKVAATGTHRE FT LLDSEPGYRALVARDAEDGEAAEEGEPAR" FT RBS complement(250848..250854) FT misc_feature complement(250952..251578) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 40.90, E-value 1.5e-08" FT misc_feature complement(251129..251173) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(251744..252553) FT /note="Pfam match to entry PF00664 ABC_membrane, ABC FT transporter transmembrane region., score 38.70, E-value FT 1.3e-07" FT CDS complement(252646..254529) FT /transl_table=11 FT /gene="SCO5450" FT /gene_synonym="SC3D11.07c" FT /product="putative ABC transporter" FT /note="SC3D11.07c, probable ABC transporter, len: 627aa; FT similar to many eg. TRNEW:CAB66302 (EMBL:AL136519) ABC FT transporter protein, ATP-binding component from FT Streptomyces coelicolor (1243 aa) fasta scores; opt: 1238, FT z-score: 1250.8, E(): 0, 38.7% identity in 633 aa overlap. FT Contains Pfam match to entry PF00005 ABC_tran, ABC FT transporter, Pfam match to entry PF00664 ABC_membrane, ABC FT transporter transmembrane region, Prosite match to PS00211 FT ABC transporters family signature and PS00017 FT ATP/GTP-binding site motif A (P-loop)." FT /db_ |