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EBI DbfetchID AL939122; SV 1; linear; genomic DNA; STD; PRO; 311000 BP. XX AC AL939122; AL356813; AL359214; AL390968; AL390975; AL391751; AL391754; AC AL451182; AL512667; AL590942; AL591857; AL593842; AL596043; XX DT 25-OCT-2002 (Rel. 73, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 4) XX DE Streptomyces coelicolor A3(2) complete genome; segment 19/29 XX KW . XX OS Streptomyces coelicolor OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Streptomycineae; Streptomycetaceae; Streptomyces. XX RN [1] RP 1-311000 RA Bentley S.D.; RT ; RL Submitted (09-MAY-2002) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Streptomyces sequencing team, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL sdb@sanger.ac.uk XX RN [2] RX DOI; 10.1038/417141a RX PUBMED; 12000953. RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L., RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H., RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E., RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D., RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.; RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor RT A3(2)"; RL Nature 417(6885):141-147(2002). XX DR EMBL-CON; AL645882. DR RFAM; RF00005; tRNA. XX FH Key Location/Qualifiers FH FT source 1..311000 FT /organism="Streptomyces coelicolor" FT /strain="A3(2)" FT /mol_type="genomic DNA" FT /db_xref="taxon:1902" FT CDS 69..1559 FT /transl_table=11 FT /gene="SCO4935" FT /gene_synonym="SCK13.27" FT /product="putative integral membrane protein" FT /note="SCK13.27, possible integral membrane protein, len: FT 496 aa; C-terminal region similar to C-terminal region of FT similar to TR:Q9UX75 (EMBL:Y18930) Sulfolobus solfataricus FT hypothetical 43.0 kDa protein ORF-C10_044, 418 aa; fasta FT scores: opt: 332 z-score: 303.7 E(): 2.2e-09; 27.1% FT identity in 325 aa overlap. Contains 4 possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q9AD76" FT /db_xref="InterPro:IPR003838" FT /db_xref="UniProtKB/TrEMBL:Q9AD76" FT /protein_id="CAD30925.1" FT /translation="MFFTYLRRELRRRRKAALVVASGLALGIALVIVVDSVSSGMGRAQ FT DKVLQSLYGLGTDMTVTKAAEASSASTAERPRFRFDAQDDGSEEEQSTDRVMVQGFQTL FT ASSTVGKVAGQSGVADAVGGLSLQVVKVSGEFSRGQFTQDASGGAAGGTGQGGGPGGGQ FT SPQGRVQGGGADFDVNSYSVYGTDVTEPALGPLTTSTITSGRTFEESETDARVAVADSA FT YAKEKKLKAGSTVTVKDTKFEIVGIATADSGDAAASLYVPLKQAQTLGDAKDEVTTIYV FT KATDSQRIDGVKSAIQKNISGTTVTTSADLADTVSGSLSTASSLATGVGKWLSIVVLVA FT AFLVAGLLTSSAVSRRVREFGTLKALGWRSGRVTRQVIGEAVVNGLVGGALGIALGLAG FT AYAVTAVSPTLQAQLGGGAGGGGGAGGSGGGFGGGGLGGPGRQAAAKTLDIALTAPVSL FT TTIALAVGLAVAGGLVAGGFGGWRASRLRPADALRRVE" FT misc_feature 1311..1388 FT /note="glycine amino acids residues rich region. Also high FT in G+C content (88.46%)" FT RBS 1581..1585 FT CDS 1593..2276 FT /transl_table=11 FT /gene="SCO4936" FT /gene_synonym="SCK13.28" FT /product="putative ABC transporter ATP-binding protein" FT /note="SCK13.28, possible ABC transporter ATP-binding FT protein, len: 227 aa; similar to TR:Q9KRR8 (EMBL:AE004234) FT Vibrio cholerae ABC transporter, ATP-binding protein FT VC1568, 233 aa; fasta scores: opt: 746 z-score: 833.1 E(): FT 0; 51.1% identity in 223 aa overlap. Contains Pfam match to FT entry PF00005 ABC_tran, ABC transporter and matches to FT Prosite entries PS00017 ATP/GTP-binding site motif A FT (P-loop) and PS00211 ABC transporters family signature" FT /db_xref="GOA:Q9ADK4" FT /db_xref="HSSP:1L2T" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9ADK4" FT /protein_id="CAC18704.3" FT /translation="MYELSGVTKHYTRGKTTVHALDGVDLTIADGDRLVIQGPTGGGKS FT TLLQMLGALDRPSSGRIVLDGTDLATLPEARLTRVRSESIGFVFQSFNLIPTLTAQENV FT ETALVPLGVKAKERREQAAEALASVGLGERLGHLPGEMSGGQQQRVAIARALVKQPKVL FT LADEPTGNLDESTRDEIMDVLDRMWKELGLTFVMVTHDSAIARKAPRVATIRKGRITVK FT ENASA" FT misc_feature 1683..2243 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 194.50, E-value 1.6e-54" FT misc_feature 1704..1727 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 2016..2060 FT /note="PS00211 ABC transporters family signature" FT CDS complement(2301..2819) FT /transl_table=11 FT /gene="SCO4937" FT /gene_synonym="SCK13.29c" FT /product="hypothetical protein" FT /note="SCK13.29c, hypothetical protein, len: 172 aa; FT similar to TR:CAC04235 (EMBL:AL391515) Streptomyces FT coelicolor conserved hypothetical protein SC4B10.30c, 156 FT aa; fasta scores: opt: 215 z-score: 274.7 E(): 9.2e-08; FT 30.9% identity in 139 aa overlap" FT /db_xref="InterPro:IPR003779" FT /db_xref="UniProtKB/TrEMBL:Q7ZAI8" FT /protein_id="CAD30926.1" FT /translation="MTTTTDTTTTAEQDGTRSRLPDPTGLYPELTALSAAVQKALRNGP FT VPQATLALTRLRTAQVIGSTYHGVAATDALRKAGEEERRITAVATWQSAPCFTAPERAA FT LELAEAVLTPNPFGDRVSDDLFARLSRHYDTDGIWHLTMALGHFSLFTPVALVGKPVPG FT RPPGKNYTD" FT misc_feature complement(2790..2816) FT /note="high concentration in threonine amino acid residues" FT RBS complement(2830..2835) FT RBS 3001..3006 FT CDS 3018..3932 FT /transl_table=11 FT /gene="SCO4938" FT /gene_synonym="SCK13.30" FT /product="putative ECF-sigma factor" FT /note="SCK13.30, possible ECF-sigma factor, len: 304 aa; FT similar to TR:Q9RJS2 (EMBL:AL132707) Streptomyces FT coelicolor putative RNA polymerase sigma factor SCF51.13c, FT 298 aa; fasta scores: opt: 1110 z-score: 1299.2 E(): 0; FT 58.4% identity in 296 aa overlap. Contains Pfam match to FT entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily) FT and possible helix-turn-helix motif at residues 144..165 FT (+2.59 SD)" FT /db_xref="GOA:Q9EWW4" FT /db_xref="HSSP:1H3L" FT /db_xref="InterPro:IPR007627" FT /db_xref="UniProtKB/TrEMBL:Q9EWW4" FT /protein_id="CAD30927.1" FT /translation="MTTRSAPVTGERRQLINVAYRMLGSLTDAEDAVQEAYARWYAMPA FT DRREAVGSPGAWLTTVVSRVCLNHLRSARVRRELYVGQWLPEPLADPAERTAARTPGIA FT SDPADLITLDESVGMAFLVVLDSMSPAQRVAFVLHDVFRYPFPEVARIVGRTPAACRRL FT ASTARRGIRTAQESAATSTAQDAVVVRDLKRAWETNDVDALIRLLDPEVTAVGDGGGVV FT RTLEHPLRGREPIVRGLLRFGPRQSGQTLLERTVNGRPGLVGCQDGTVVTVYSFGVSDH FT RVRHLWAMRNPEKLRSWATAPAA" FT misc_feature 3066..3236 FT /note="Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 FT factor (ECF subfamily), score 11.30, E-value 0.006" FT CDS complement(3976..4758) FT /transl_table=11 FT /gene="SCO4939" FT /gene_synonym="SCK13.31c" FT /product="hypothetical protein SCK31.31c" FT /note="SCK13.31c, unknown, len: 260 aa" FT /db_xref="UniProtKB/TrEMBL:Q9AD74" FT /protein_id="CAD30928.1" FT /translation="MRVRRLGWAGLEIEAGGERMVIDYVRDLSPLFTGWKPGENVAVPG FT GRASAALVTHLHRDHTDASALSEVLTQGAPVLRPAPGHGDDVDNVTTLLAERELVRHRL FT AVEVVDVWSTRDLGPFRVTAVPAVDGLGDPQLNWVVEADGQRILHGGDTMFHGFWWLVA FT RRFSPFDAVFLPANGAVVDAPHLQPPSPVPAALDPRQAAAAAEILDARFAVPIHYEPEQ FT PDKIAGYVEVADPEAEFRAHAGRRAHVLAVGEWLDLAT" FT RBS complement(4765..4771) FT stem_loop complement(4804..4849) FT /note="possible stem loop. Score 60: 20/20 (100%) matches, FT 0 gaps" FT CDS 4860..5462 FT /transl_table=11 FT /gene="SCO4940" FT /gene_synonym="SCK13.32" FT /product="putative tetR-family transcriptional regulator" FT /note="SCK13.32, possible tetR-family transcriptional FT regulator, len: 200 aa; similar to TR:Q9KZX2 FT (EMBL:AL353815) Streptomyces coelicolor putative FT transcriptional regulator SCD6.32c, 200 aa; fasta scores: FT opt: 183 z-score: 230.1 E(): 2.8e-05; 28.3% identity in 159 FT aa overlap. Contains Pfam match to entry PF00440 tetR, FT Bacterial regulatory proteins, tetR family and possible FT helix-turn-helix motif at residues 33..54 (+4.53 SD)" FT /db_xref="GOA:Q8CJS4" FT /db_xref="InterPro:IPR001647" FT /db_xref="PDB:2HYJ" FT /db_xref="UniProtKB/TrEMBL:Q8CJS4" FT /protein_id="CAD55220.1" FT /translation="MSPRRSAAEAQATRGRILGRAAEIASEEGLDGITIGRLAEELEMS FT KSGVHKHFGTKETLQISTLDKAFVDFWHRVVEPALAEPPGLRRLRAVCANSVGYLEEPL FT LPGGCLLTAALSEYDGRPGRVRDAVAEVWSRWREQLRADLTAAVDKGELPAGFDVEQAL FT FEIVAAGLALNAAMQLQHDRTAADRARRAIERALAQS" FT misc_feature 4908..5036 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 34.50, E-value FT 3.1e-07" FT CDS complement(5466..5783) FT /transl_table=11 FT /gene="SCO4941" FT /gene_synonym="2SCK31.01c" FT /product="hypothetical protein" FT /note="2SCK31.01c, hypothetical protein, len: 105 aa; FT similar to TR:Q9KZT7 (EMBL:AL353832) Streptomyces FT coelicolor hypothetical 20.2 kDa protein (fragment) FT SCE6.01c, 183 aa; fasta scores: opt: 191 z-score: 223.2 FT E(): 6.8e-05; 41.5% identity in 82 aa overlap" FT /db_xref="UniProtKB/Swiss-Prot:Q9EWW3" FT /protein_id="CAC21613.2" FT /translation="MTEALTHVIDHEGQGTPATVRLTVLPSGHTRVGVTDPDPRVPPLL FT PGPAGVTDESGRGLALLDAPAPRWGVEQRGDRRAVRCEPAGEPPLDDVRTPAAPAVRSG FT R" FT CDS complement(5964..6644) FT /transl_table=11 FT /gene="SCO4942" FT /gene_synonym="2SCK31.02c" FT /product="putative regulatory protein" FT /note="2SCK31.02c, possible regulatory protein, len: 226 FT aa; similar to TR:Q9KXX1 (EMBL:AL357432) Streptomyces FT coelicolor putative transcriptional regulator SCD95A.03c, FT 199 aa; fasta scores: opt: 414 z-score: 464.7 E(): 2.4e-18; FT 38.2% identity in 204 aa overlap. Contains Pfam match to FT entry PF00440 tetR, Bacterial regulatory proteins, tetR FT family" FT /db_xref="GOA:Q9EWE9" FT /db_xref="InterPro:IPR012287" FT /db_xref="PDB:2PZ9" FT /db_xref="UniProtKB/TrEMBL:Q9EWE9" FT /protein_id="CAD30929.1" FT /translation="MVAYPGPMPRSPSPGQTPDAPTSGGGSTDSTRQRIVAAAKEEFAR FT HGIAGARVDRIAKQARTSKERVYAYFRSKEALYAHVAERETTALIEATQLDPADLPGYA FT GILFDHFAARPDHYRLITWGRLELAESADNTSGPLQATIAGKLDKLRDAQRIGLLDPAW FT DPVDVLALINQIAMTWAGQPEIAAAAADQAVDPSVTARRAALVTAVEHMFPRPDRDQRP FT NRLT" FT misc_feature complement(6402..6542) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 49.20, E-value FT 4.1e-11" FT RBS 6753..6757 FT CDS 6765..7757 FT /transl_table=11 FT /gene="SCO4943" FT /gene_synonym="2SCK31.03" FT /product="putative oxidoreductase" FT /note="2SCK31.03, probable oxidoreductase, len: 330 aa; FT similar to TR:AAG05923 (EMBL:AE004681) Pseudomonas FT aeruginosa probable oxidoreductase PA2535, 331 aa; fasta FT scores: opt: 1001 z-score: 1136.6 E(): 0; 48.2% identity in FT 328 aa overlap. Contains Pfam match to entry PF00248 FT aldo_ket_red, Aldo/keto reductase family" FT /db_xref="GOA:Q9EWV3" FT /db_xref="HSSP:1HW6" FT /db_xref="InterPro:IPR001395" FT /db_xref="UniProtKB/TrEMBL:Q9EWV3" FT /protein_id="CAC21631.2" FT /translation="MQHRTLGQQGLRVSALGLGVMGMSLAYGPSNDEDGISTIHRAHEL FT GVDFFDTAELYGQGTGSNETLLGNAVNDFRDEVVLATKFGFDMTSKSLGSGVNSRPENI FT REVAENSLRYLRTDRIDLFYQHISDPDVPAEEVAGTVGDLITEGKVRYFGLSNVGPRYI FT RRAHAVTPVTALQYEYSIFEREVEDEILPVVRELGIGLVPYSPLGRGFLSGVVRPAGEY FT PEDDMRRWDERWQGENYAYNLNAAEQLRKLAATKGITPAQLALAWLLAQGEDVVPIPGT FT RSAARLEENVGAIDAELTEADLARIREVIPQGSAGSRYPASMMAGFRTD" FT misc_feature 7374..7682 FT /note="Pfam match to entry PF00248 aldo_ket_red, Aldo/keto FT reductase family, score 21.20, E-value 4.9e-05" FT CDS complement(7855..8730) FT /transl_table=11 FT /gene="SCO4944" FT /gene_synonym="2SCK31.04c" FT /product="putative DNA-binding protein" FT /note="2SCK31.04c, possible DNA-binding protein, len: 314 FT aa; similar to TR:Q9RI67 (EMBL:AL109949) Streptomyces FT coelicolor putative DNA-binding protein SCJ11.39c, 279 aa; FT fasta scores: opt: 544 z-score: 640.7 E(): 3.8e-28; 40.2% FT identity in 249 aa overlap. Contains Pfam match to entry FT PF01381 HTH_3, Helix-turn-helix and possible FT helix-turn-helix motif at residues 64..85 (+4.67 SD)" FT /db_xref="GOA:Q9ADL0" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q9ADL0" FT /protein_id="CAD30930.1" FT /translation="MDGQLDRRAELSEFLRTRRARLKPEDVGLESYGRQRRVPGLRREE FT LAQLAGVSVAYYTRLEQGNGQNVSAEVLDAIARALRLTDAEQAHLTHLARPKQQRRRAG FT AARGKQPVRVALLQLLDSIDTVPAYVSGRRSEILAWNRMAAALFGDWGKLPAAERNWAR FT LVFLNPDYRELFVDWDQKAYDMVSFLRMDAGRHPDDPRLSALVGELSVKSEEFRRLWAT FT HDVKEKSYGVKRMRHPLVGDLTLSFETFRLVDDDEQAFITYHAEPGSPSADALRLLASW FT GTDAAASLPA" FT misc_feature complement(8470..8643) FT /note="Pfam match to entry PF01381 HTH_3, Helix-turn-helix, FT score 25.50, E-value 0.0012" FT RBS complement(8733..8737) FT RBS 8887..8890 FT CDS 8899..9939 FT /transl_table=11 FT /gene="SCO4945" FT /gene_synonym="2SCK31.05" FT /product="putative dehydrogenase" FT /note="2SCK31.05, probable dehydrogenase, len: 346 aa; FT highly similar to SW:ADH_MYCTU (EMBL:AL021287) FT Mycobacterium bovis NADP-dependent alcohol dehydrogenase FT AdhC, 346 aa; fasta scores: opt: 1508 z-score: 1698.9 E(): FT 0; 64.5% identity in 346 aa overlap. Contains Pfam match to FT entry PF00107 adh_zinc, Zinc-binding dehydrogenases and FT matches to Prosite entries PS00059 Zinc-containing alcohol FT dehydrogenases signature and PS00017 ATP/GTP-binding site FT motif A (P-loop)" FT /db_xref="GOA:Q9EWF1" FT /db_xref="HSSP:1UUF" FT /db_xref="InterPro:IPR013154" FT /db_xref="UniProtKB/TrEMBL:Q9EWF1" FT /protein_id="CAD30931.1" FT /translation="MTTVAAYAAPAAKAPLERTTIERREVREHDVLIDIKFAGICHSDI FT HQAREGWGEAIFPMVPGHEIAGIVSEVGPGVTRFKVGDRVGVGCMVDSCRECENCKAGR FT EQYCTSGNTGTYNAVGRDGEVTYGGYSEKVVVDENFVLGIPEGIALDEAAPLLCAGITT FT YSPLKRWNAGPGKKVAVVGLGGLGHMAVKLAHALGAEVTVLSQSLRKKDDGLKLGADHY FT YATSDPATFEELSGTFDLIVSTVSAPLDLGAYLGLLKTEGTLANVGAPEEPVSLNLFAL FT LGGGKSLSGSMIGGIAETQEMLDFCAEHGIGAEIELIAASEINEAYERVLSSDVRYRFV FT IDTATI" FT misc_feature 8941..9927 FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score 372.20, E-value 5.2e-108" FT misc_feature 9082..9126 FT /note="PS00059 Zinc-containing alcohol dehydrogenases FT signature" FT misc_feature 9736..9759 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 10103..10106 FT CDS 10116..10907 FT /transl_table=11 FT /gene="SCO4946" FT /gene_synonym="2SCK31.06" FT /product="conserved hypothetical protein" FT /note="2SCK31.06, hypothetical protein, len: 263 aa; highly FT similar to TR:Q9L114 (EMBL:AL159139) Streptomyces FT coelicolor hypothetical 27.0 kDa protein SCL6.02, 255 aa; FT fasta scores: opt: 711 z-score: 830.9 E(): 0; 49.4% FT identity in 253 aa overlap" FT /db_xref="GOA:Q9EWF2" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9EWF2" FT /protein_id="CAD30932.1" FT /translation="MTYHASTPSTPLLVTGGTGTLGGHVVPLLREAGHDVRVLTRRTRP FT ATGNGITYVTGDLRTGEGVEAAVDGVHTVLHLAGGPKGDDEATRTLVRAAARADVRHLA FT YISVVGADRVPLAWLRTKLESERAIADSGLGWTVLRAAQFHELTLTMIEKMTRLPVLPV FT PGGLRLQPVAAREVAVRLAELTLAEPSGRVPDMTGPEVLDLATLAHSYLDLRGGRRRPK FT LPVRIPGKAGRAYRSGQNLTLEDALVGKVTWTEFLAERAAV" FT CDS 11148..14831 FT /transl_table=11 FT /gene="SCO4947" FT /gene_synonym="narG3" FT /gene_synonym="2SCK31.07" FT /product="nitrate reductase alpha chain NarG3" FT /note="2SCK31.07, narG3, nitrate reductase alpha chain, FT len: 1227 aa; highly similar to SW:NARG_BACSU (EMBL:Z49884) FT Bacillus subtilis nitrate reductase alpha chain (EC FT 1.7.99.4)NarG, 1228 aa; fasta scores: opt: 4080 z-score: FT 4618.0 E(): 0; 49.5% identity in 1206 aa overlap and to FT TR:O86717 (EMBL:AL031515) Streptomyces coelicolor NarG, FT putative nitrate reductase alpha chain SC5C7.20, 1231 aa; FT fasta scores: opt: 5648 z-score: 5294.1 E(): 0; 66.6% FT identity in 1232 aa overlap. Contains Pfam matches to FT entries PF00384 molybdopterin, Prokaryotic molybdopterin FT oxidoreductases and PF01568 Molydop_binding, Molydopterin FT dinucleotide binding domain and matches to Prosite entries FT PS00551 Prokaryotic molybdopterin oxidoreductases signature FT 1 and PS00490 Prokaryotic molybdopterin oxidoreductases FT signature 2" FT /db_xref="GOA:Q9EWF3" FT /db_xref="HSSP:1R27" FT /db_xref="InterPro:IPR006468" FT /db_xref="UniProtKB/TrEMBL:Q9EWF3" FT /protein_id="CAD30933.1" FT /translation="MADAADRLLKAGQLLRRSPTTLDLRAVYRTDQNVNDRPYRERWAH FT DKVVRSTHGVNCTGSCSWKVYVKDGLITWETQQTDYPSVGPDRPEYEPRGCPRGASFSW FT YTYSPTRVRHPLARGVLVEMYRDAKRRHGGDPVAAWAELTSDPEKRRRYQSARGRGGFV FT RVDWDEALEIAAAAQVHTIAEYGPDRVAGFSPIPAMSMASHAVGARYHSLIGAPMISFY FT DWYADLPIASPQVFGDQTDVPESGDWWDAAYLMLWGSNVPVTRTPDAHWMAEARYRGQK FT VVVVSPDYADATKFADEWLHPHPGTDGALAMAMGHVLLTEFFVRRQVPYFTDYVKRFTD FT LPFLVALDEHAAGRWTPGKFVTAADLGLGRHADAGARAWMPVLIDADTDDVVVPNGTLG FT DRWGKGGEGRWNLDLGGTDPLLTLHGHTGGRGDNGVEVVLPRFDEPGATVVRGVPAREI FT GGRLVTTVYDLLLAQYAVARPGLAGHWPTGYDDAEQPCTPAWQERLTSVPAEAAVRAAR FT EFARTAEQTRGRCMIVMGAGTNHWFHSDTIYRSFLSLLILTGCQGVNGGGWAHYVGQEK FT VRPYTGWQQLSTAADWVRPSRQMAGTPYWYLHTGQWRYESHAADALASPTAPGTLAGLH FT TADLVAQSARLGWMPSYPTFDANPLDLGRRARESGQEPGDWIAEQLGSGAVDFACEDPD FT APRNWPRVLTVWRANLIGSSAKGNEYFLRHLLGARDGATSSEAPPEHRPRSVAWRDDAP FT EGKLDLLLSLDFRMTSTTLFSDLVLPAATWYEKHDLSSTDMHPFVHAFSPAINPPWQAR FT TDFEIFHSLARRLSELAAGRLGTAHDLVATALQHDTPGETAQPGGRVTDWRDGRTPIEP FT GRNAPQVSLVERDYTAVADRLAAFGPLAEEHGMTVKGVTVNPHEESRWLAARCGTAPAG FT PARGRPLLDTDVKFCEAILALSGTTNGRLAAEGFDRLADRVGPGAGLAELAASVGERRV FT VFSDTQERPVQVGASFEWSGKEAPDRRYSPFTVNTEHKKPWHTLTGRQHFYVDHDWMAE FT LGEQLPVYRPPLNLAELGDAPIPTGDGRAVTVRYLTPHAKWSIHSEYQENLLMQTLARG FT GPVVWMSPADADAIGAADNDWVEAVNAHGVVVARAIVSHRVPDGTVLMYHVQERLVNVP FT KSEANGRRGGVHNSLTKLLVKPTHLIGGYGQLSFAPNYYGPTGNQRDAVTTIRRRSQEV FT TY" FT misc_feature 11298..11354 FT /note="PS00551 Prokaryotic molybdopterin oxidoreductases FT signature 1" FT misc_feature 13422..13613 FT /note="Pfam match to entry PF00384 molybdopterin, FT Prokaryotic molybdopterin oxidoreductases, score 97.30, FT E-value 9e-31" FT misc_feature 13449..13502 FT /note="PS00490 Prokaryotic molybdopterin oxidoreductases FT signature 2" FT misc_feature 14385..14750 FT /note="Pfam match to entry PF01568 Molydop_binding, FT Molydopterin dinucleotide binding domain, score 118.70, FT E-value 1.1e-31" FT CDS 14840..16486 FT /transl_table=11 FT /gene="SCO4948" FT /gene_synonym="narH3" FT /gene_synonym="2SCK31.08" FT /product="nitrate reductase beta chain NarH3" FT /note="2SCK31.08, narH3, nitrate reductase beta chain, len: FT 548 aa; highly similar to SW:NARH_BACSU (EMBL:Z49884) FT Bacillus subtilis nitrate reductase beta chain NarH, 487 FT aa; fasta scores: opt: 2088 z-score: 2047.9 E(): 0; 58.2% FT identity in 483 aa overlap and to TR:O86716 (EMBL:AL031515) FT Streptomyces coelicolor NarH, putative nitrate reductase FT beta chain SC5C7.19, 531 aa; fasta scores: opt: 2542 FT z-score: 2343.2 E(): 0; 71.6% identity in 503 aa overlap" FT /db_xref="GOA:Q9EWF4" FT /db_xref="HSSP:1R27" FT /db_xref="InterPro:IPR017896" FT /db_xref="UniProtKB/TrEMBL:Q9EWF4" FT /protein_id="CAD30934.1" FT /translation="MAQVAMVMNLDKCIGCHTCSVTCKQTWTNRTGTEYVWFNNVETRP FT GQGYPRGHEDQEKWKGGWHLKGGRLVPRTGGRARRLARLFANPELPTLDDYYQPWTYDY FT ENLTTAPLGDDIPTAPPRSAIDGRPTEITWGPNWDDDLGGGPAQLAADPLLARMSEQVR FT LDYERAFMFYLPRICEHCLNPSCVAVCPSGALYKRVEDGIVLVDQDRCRGWRMCVSGCP FT YKKVYFNHSTGKAEKCTFCYPRIEAGDPTVCSETCVGRLRYLGVMLYDPDKVGAAASVT FT DEKDLYEAQLGCFLDPDDPEVARAAQASGIPHDWVEAARRSPVHALITRYRVALPLHPE FT YRTMPMVWYVPPLSPVVDALTGTGHDGEDPAALFGAIDTLRIPLGYLAELFTAGDPGPV FT EAALCRLAAMRSHMRRVNLGEEQDPRIAEAVGLDEPGILELYRLLALAKYDERYVIPTA FT YTGSVPDPGGTGAGCSLDGVGGPGMMPEGAGGGPGFGEFDPEAFHAPPTAGSGTSSALR FT GRVNLLNWNGKGRPNGLFPRARGAVRTEPEL" FT RBS 16471..16474 FT CDS 16483..17145 FT /transl_table=11 FT /gene="SCO4949" FT /gene_synonym="narJ3" FT /gene_synonym="2SCK31.09" FT /product="nitrate reductase delta chain NarJ3" FT /note="2SCK31.09, narJ3, nitrate reductase delta chain, FT len: 237 aa; similar to SW:NARJ_BACSU (EMBL:Z49884) FT Bacillus subtilis nitrate reductase delta chain (EC FT 1.7.99.4) NarJ, 184 aa; fasta scores: opt: 332 z-score: FT 411.9 E(): 2.1e-15; 35.0% identity in 163 aa overlap and to FT TR:Q9RI30 (EMBL:AL109989) Streptomyces coelicolor NarJ2 FT SCJ12.30 , 267 aa; fasta scores: opt: 436 z-score: 447.2 FT E(): 3.3e-19; 41.7% identity in 204 aa overlap" FT /db_xref="GOA:Q9EWF5" FT /db_xref="InterPro:IPR003765" FT /db_xref="UniProtKB/TrEMBL:Q9EWF5" FT /protein_id="CAD30935.1" FT /translation="MSRSLGRAATTTNAPVVFQAAALLLAYPDRDWPRRPHTVRDTVAA FT LPGPEIQLLLSFCDRAEREDPLAVAARYVATFDRSRRRCLYLTYYTDGDTRRRGAALAR FT IKSVYRTHGWLPPDDELPDFLPLMLEFAARTPEAGTALLTEHRAAIEVLRYALEAHRSP FT YAALLQAVGRCLPGRAPASREEALRLTRTGPPTEAVGLDVLGPFPAQPRPHDDGARR" FT RBS 17131..17134 FT CDS 17142..17855 FT /transl_table=11 FT /gene="SCO4950" FT /gene_synonym="narI3" FT /gene_synonym="2SCK31.10" FT /product="nitrate reductase gamma chain NarI3" FT /note="2SCK31.10, narI3, nitrate reductase gamma chain, FT len: 237 aa; highly similar to SW:NARI_BACSU (EMBL:Z49884) FT Bacillus subtilis nitrate reductase gamma chain (EC FT 1.7.99.4) NarI, 223 aa; fasta scores: opt: 792 z-score: FT 991.9 E(): 0; 49.6% identity in 234 aa overlap and to FT TR:Q9RI29 (EMBL:109989) Streptomyces coelicolor putative FT nitrate reductase delta chain NarI2 SCJ12.31, 256 aa; fasta FT scores: opt: 813 z-score: 891.7 E(): 0; 54.3% identity in FT 230 aa overlap. Contains possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q9EWF6" FT /db_xref="HSSP:1Q16" FT /db_xref="InterPro:IPR003816" FT /db_xref="UniProtKB/TrEMBL:Q9EWF6" FT /protein_id="CAD30936.1" FT /translation="MRHLHTALWGVLPYLTLVVLVAGTAWRYRYDRFGFTTRSSQLHES FT RLLRIAGPLFHYGLLFVIAGHVAGLLVPESLTDRLHVSEHLYHANALIAGGTAGLATLA FT GLALLLYRRLRTPAIRAATSRSDRVVYPLLLTVVLAGLTATASGATAASTYDYRLGVSV FT WFRSLFALDPDVTAMAQAPLVYRLHALLAMALFALWPYTRLIHAFTAPLGYLVRPYVVY FT RYRGRGEVGAGRPGR" FT CDS complement(17898..18935) FT /transl_table=11 FT /gene="SCO4951" FT /gene_synonym="2SCK31.11c" FT /product="putative aldoketoreductase" FT /note="2SCK31.11c, probable aldoketoreductase, len: 345 aa; FT similar to TR:Q9XC70 (EMBL:AF147704) Streptomyces fradiae FT NDP-hexose 2,3-enoyl reductase TylCII, 329 aa; fasta FT scores: opt: 726 z-score: 830.3 E(): 0; 41.3% identity in FT 320 aa overlap. Contains 2x Pfam matches to entry PF00248 FT aldo_ket_red, Aldo/keto reductase family" FT /db_xref="GOA:Q9ADK9" FT /db_xref="HSSP:1HW6" FT /db_xref="InterPro:IPR020471" FT /db_xref="UniProtKB/TrEMBL:Q9ADK9" FT /protein_id="CAD30937.1" FT /translation="MQYRTLGRTGVQVSSLALGAMNFGSIGRTTQDEATAIVDAALEGG FT INLIDTADMYGRGESEEMVGKAIAGRRDDIVLATKANMPMSDEPNHQGSSRRWLVTALD FT NSLRRLGVDHVDLYQIHRWDPATSDEETLSALTDLQRAGKIRYFGSSTFPAYRIVEAQW FT AAREHRLSRYVTEQPSYSLLQRGIESHVLPVTEQYGLGVLVWSPLASGWLSGAVRAGRE FT AATHRSAVLPERFDTALPANRARLDAVEKLAAVADEAGLTLIQLALGFVTAHPAVTAAL FT VGPRTLNHLHSQLAAADTVLSDDVLDAVDAVVAPGTDLAAHEKFDATPALLDPALRRRR FT RPAAG" FT misc_feature complement(18573..18632) FT /note="Pfam match to entry PF00248 aldo_ket_red, Aldo/keto FT reductase family, score 11.80, E-value 0.024" FT misc_feature complement(18711..18854) FT /note="Pfam match to entry PF00248 aldo_ket_red, Aldo/keto FT reductase family, score 1.20, E-value 25" FT RBS complement(18943..18947) FT CDS 19080..19676 FT /transl_table=11 FT /gene="SCO4952" FT /gene_synonym="2SCK31.12" FT /product="putative tetR-family transcriptional regulator" FT /note="2SCK31.12, probable tetR-family transcriptional FT regulator, len: 198 aa; similar to TR:Q9RJL5 FT (EMBL:AL121849) Streptomyces coelicolor putative FT tetR-family transcriptional regulator SCF6.16, 194 aa; FT fasta scores: opt: 355 z-score: 451.5 E(): 1.3e-17; 35.1% FT identity in 185 aa overlap. Contains Pfam match to entry FT PF00440 tetR, Bacterial regulatory proteins, tetR family FT and possible helix-turn-helix motif at residues 42..63 FT (+4.18 SD)" FT /db_xref="GOA:Q9ADK8" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9ADK8" FT /protein_id="CAD30938.1" FT /translation="MKDGEAATGQAASRPKRADARRNEKNLLDAAAAVFVRSGVEAPVR FT DIAAEAGVGTATIYRHFPTRADLIIGVYRHQVEACAEAGPALLASSPTPYAALAGWIDL FT FVDFLVTKHGLAAVLQSDSAGFETLHAYFLDRLVPVCTDLLAAATDSGEIDTDVPPLAL FT MRGVGNLCIGAETPNPSYDARQLVRILIAGLRAAD" FT misc_feature 19158..19295 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 54.40, E-value FT 1.8e-12" FT CDS 19724..19918 FT /transl_table=11 FT /gene="SCO4953" FT /gene_synonym="2SCK31.13" FT /product="hypothetical protein 2SCK31.13" FT /note="2SCK31.13, unknown, len: 64 aa" FT /db_xref="GOA:Q9ADK7" FT /db_xref="InterPro:IPR003325" FT /db_xref="UniProtKB/TrEMBL:Q9ADK7" FT /protein_id="CAD30939.1" FT /translation="MLDKFPALTELGQLRVSDGRPHETALVLGSFRRRSNGDWDFVVGG FT KGYSGGLEELLRDFGVEVD" FT CDS complement(19941..20534) FT /transl_table=11 FT /gene="SCO4954" FT /gene_synonym="2SCK31.14c" FT /product="hypothetical protein 2SCK31.14c" FT /note="2SCK31.14c, unknown, len: 197 aa" FT /db_xref="UniProtKB/TrEMBL:Q9ADK6" FT /protein_id="CAD30940.1" FT /translation="MQQPQREVRAVHTASTVTVYQAYSPEIGLPAIREGRFPAAWKRDR FT MTWIKPSFLWMMYRCGWAAKAGQETVLAVEIGREGFEWALRHACLSSYQPGVHPDRATW FT QREVKRSPTRVQWDPERDLRLQPLPYRSLQLGLAGEAARRYADEWTVAIRDVTPLAHEI FT HGLVRDGDLDAARRLLPREQPYPAAEELLSNLRP" FT CDS complement(20665..21852) FT /transl_table=11 FT /gene="SCO4955" FT /gene_synonym="2SCK31.15c" FT /product="putative ATP/GTP-binding protein" FT /note="2SCK31.15c, hypothetical protein, len: 395 aa; FT similar to TR:Q9X8V7 (EMBL:AL078610) Streptomyces FT coelicolor hypothetical 43.9 kDa protein SCH35.49c, 410 aa; FT fasta scores: opt: 1788 z-score: 1973.1 E(): 0; 63.8% FT identity in 398 aa overlap. Contains match to Prosite entry FT PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="InterPro:IPR007141" FT /db_xref="UniProtKB/TrEMBL:Q9ADK5" FT /protein_id="CAD30941.1" FT /translation="MGLALAGAGLATVGTAPAAAGSYDCPSGYFCGWTGESANGSMWKT FT NKSVADLGGWDNKIRSYVNRTTSVACVYEDKNYTPWGGYWAQEPNSPGEYNGDPVATTS FT SVKFVRTERECSQPAYPSWSSETSPKALGFGDLNGDRRADVVTRDEAGRLWFSPGDTTG FT RLIGTGGWNAMSALTRHGDFSRDGREDLIAREASTGKLWLYPGTGTGSLGSRKLIGKSG FT WNAMNRVTAFGDLTGDGRSDLIAVEKATARLWLYPGTSTGTLGARKLIGKSGWNAMNAL FT IGMGDVTGDGRPDLYAREASTGKLWLYPGTSTGTLGSRTLVGTGGWNAMAHFLPVGDFS FT GDGVPDLATVTNEKYVLDGYPGNLGWLVTYRGRGNGFLTSGVPTHGEWWGLNGFV" FT misc_feature complement(21034..21057) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 21999..22003 FT CDS 22010..22528 FT /transl_table=11 FT /gene="SCO4956" FT /gene_synonym="2SCK31.16" FT /product="putative peptide methionine sulfoxide reductase" FT /note="2SCK31.16, probable peptide methionine sulfoxide FT reductase, len: 172 aa; similar to SW:PMSR_ECOLI FT (EMBL:M89992) Escherichia coli peptide methionine sulfoxide FT reductase MsrA, 211 aa; fasta scores: opt: 437 z-score: FT 538.0 E(): 2e-22; 44.2% identity in 165 aa overlap. FT Contains Pfam match to entry PF01625 PMSR, Peptide FT methionine sulfoxide reductase" FT /db_xref="GOA:Q9EWF7" FT /db_xref="HSSP:1NWA" FT /db_xref="InterPro:IPR002569" FT /db_xref="UniProtKB/Swiss-Prot:Q9EWF7" FT /protein_id="CAD30942.1" FT /translation="MAAQTQRAVLAGGCFWGMEELIRRLPGVTATRVGYTGGDVPNATY FT RNHGTHAEAIEILFDPEATDYRALLEFFFQIHDPSTKNRQGNDIGLSYRSAIYYVDDEQ FT KRIAEDTIADVDASGLWPGKVVTEVEPVGPFWEAEPEHQDYLQRYPDGYTCHFPRPGWR FT LPARSGSEG" FT misc_feature 22025..22486 FT /note="Pfam match to entry PF01625 PMSR, Peptide methionine FT sulfoxide reductase, score 322.70, E-value 4.3e-93" FT CDS complement(22632..23750) FT /transl_table=11 FT /gene="SCO4957" FT /gene_synonym="2SCK31.17c" FT /product="putative membrane protein" FT /note="2SCK31.17c, putative membrane protein, len: 372 aa; FT similar to TR:Q9S2T3 (EMBL:AL096884) Streptomyces FT coelicolor hypothetical 40.5 kDa protein SC4G6.25, 376 aa; FT fasta scores: opt: 334 z-score: 393.9 E(): 2.1e-14 34.3% FT identity in 324 aa overlap. Contains possible hydrophobic FT membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9EWF8" FT /protein_id="CAD30943.1" FT /translation="MEILWVLMALVMLGFVLLQVSRRRRGAVGLVEPGHPDAADPANYG FT FAREEELDIRMPGPDQDLLDVLDLVQRTQDYRGAMQLLAGTEAEGERRWQRVQAFAGAA FT SLELRQRPGGVGETPGGQWLRVWRAEAPKDAGGAAVHAEFLVQQAWRTSTPGSDDFRII FT MEEARAACGEAALLAPGDPVPYIVELSVARGLGYSREEFEQLWLKILDRAPNHMGAHLA FT ALQYWCEKWHGSRQLAYSFAEAAAARAPRGSLLAAMPLFAVFEHLPEVNLVSGFYQSEV FT VTKAVHGALHAVHSARPDDPMQAHVRHLLVFFLVRGERWAEAMNQLTVIDGHVGALPWT FT LSTDPAAEFAVYRALAVAGYEANGGSPATLPH" FT CDS 23841..25001 FT /transl_table=11 FT /gene="SCO4958" FT /gene_synonym="metB" FT /gene_synonym="2SCK31.18" FT /product="cystathionine gamma-synthase" FT /note="2SCK31.18, metB, cystathionine gamma-synthase, len: FT 386 aa; highly similar to TR:Q9RQ97 (EMBL:AF126953) FT Corynebacterium glutamicum cystathionine gamma-synthase FT MetB, 396 aa; fasta scores: opt: 1497 z-score: 1715.4 E(): FT 0; 59.2% identity in 377 aa overlap. Contains Pfam match to FT entry PF01053 Cys_Met_Meta_PP, Cys/Met metabolism FT PLP-dependent enzyme and match to Prosite entry PS00179 FT Aminoacyl-transfer RNA synthetases class-II signature 1" FT /db_xref="GOA:Q9EWF9" FT /db_xref="HSSP:1N8P" FT /db_xref="InterPro:IPR015422" FT /db_xref="UniProtKB/TrEMBL:Q9EWF9" FT /protein_id="CAD30944.1" FT /translation="MPMSDRHISQHFETLAIHAGNTADPLTGAVVPPIYQVSTYKQDGV FT GGLRGGYEYSRSANPTRTALEENLAALEGGRRGLAFASGLAAEDCLLRTLLRPGDHVVI FT PNDAYGGTFRLFAKVATRWGVEWSVADTSDAAAVRAALTPKTKAVWVETPSNPLLGITD FT IAQVAQVARDAGARLVVDNTFATPYLQQPLALGADVVVHSLTKYMGGHSDVVGGALIVG FT DQELGEELAFHQNAMGAVAGPFDSWLVLRGTKTLAVRMDRHSENATKVADMLSRHARVT FT SVLYPGLPEHPGHEVAAKQMKAFGGMVSFRVEGGEQAAVEVCNRAKVFTLGESLGGVES FT LIEHPGRMTHASAAGSALEVPADLVRLSVGIENADDLLADLQQALG" FT misc_feature 23877..24998 FT /note="Pfam match to entry PF01053 Cys_Met_Meta_PP, Cys/Met FT metabolism PLP-dependent enzyme, score 745.00, E-value FT 3.3e-220" FT misc_feature 24768..24839 FT /note="PS00179 Aminoacyl-transfer RNA synthetases class-II FT signature 1" FT CDS complement(25012..25269) FT /transl_table=11 FT /gene="SCO4959" FT /gene_synonym="2SCK31.19c" FT /product="putative membrane protein" FT /note="2SCK31.19c, possible membrane protein, len: 85 aa. FT Contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9EWG0" FT /protein_id="CAD30945.1" FT /translation="MNRPRREAAARRIMEQSPPRVPADLYAEAVRRGGRMLRRRTAARR FT LMWLLLGAAAVAFTVWALTVQPWVEPPSETTPPVTGWEGW" FT RBS complement(25275..25279) FT CDS complement(25316..25822) FT /transl_table=11 FT /gene="SCO4960" FT /gene_synonym="2SCK31.20c" FT /product="putative sigma factor" FT /note="2SCK31.20c, possible sigma factor, len: 168 aa; FT similar to SW:RPOE_STRCO (EMBL:L29636) Streptomyces FT coelicolor RNA polymerase sigma-E factor SigE, 176 aa; FT fasta scores: opt: 108 z-score: 140.1 E(): 2.9; 30.8% FT identity in 156 aa overlap" FT /db_xref="GOA:Q9EWG1" FT /db_xref="UniProtKB/TrEMBL:Q9EWG1" FT /protein_id="CAD30946.1" FT /translation="MRERHASRNARRAREFEAFVAGAAGRLLHAATLLTAEAPDANPRA FT RRLLALSLAHTYADWDRLHGEDPYDRARQHLATRFARAAWHRYGALGRTRRHPAGPLGG FT LAPQERLLLVLRLYEGVAEEQTAALLGLPVERVRTICDRATAALLRPPPSPARPVTADA FT RAATP" FT RBS complement(25827..25831) FT CDS complement(26005..26505) FT /transl_table=11 FT /gene="SCO4961" FT /gene_synonym="2SCK31.21c" FT /product="putative marR-family transcriptional regulator" FT /note="2SCK31.21c possible marR-family transcriptional FT regulator, len: 166 aa; similar to SW:YXAD_BACSU FT (EMBL:AB005554) Bacillus subtilis hypothetical FT transcriptional regulator in AsnH-GntR intergenic region FT YxaD, 143 aa; fasta scores: opt: 268 z-score: 338.9 E(): FT 2.4e-11; 35.0% identity in 137 aa overlap. Contains Pfam FT match to entry PF01047 MarR, MarR family and possible FT helix-turn-helix motif at residues 58..79 (+2.70 SD)" FT /db_xref="GOA:Q9EWG2" FT /db_xref="InterPro:IPR000835" FT /db_xref="UniProtKB/TrEMBL:Q9EWG2" FT /protein_id="CAD30947.1" FT /translation="MDMTTAGDTGLLETLQHEVALFARRAEQTRLGGVGQVRNSMDRAA FT YLLLNRLDKEGPMGVKALAASMGIDSSTVTRQVAPLVDTGLVKRTSHPEDGRAVVLQLS FT PRGVARLEEVRSSRRQLMAELTHDWAPQERETFCALLARFNGALSARMAPSGVSPTDAP FT SGS" FT misc_feature complement(26074..26385) FT /note="Pfam match to entry PF01047 MarR, MarR family, score FT 96.00, E-value 7.4e-25" FT RBS 26668..26671 FT CDS 26674..27903 FT /transl_table=11 FT /gene="SCO4962" FT /gene_synonym="2SCK31.22" FT /product="putative amino acid deaminase" FT /note="2SCK31.22, probable amino acid deaminase, len: 416 FT aa; similar to SW:THD2_ECOLI (EMBL:M21312) Escherichia coli FT threonine deaminase TdcB, 409 aa; fasta scores: opt: 899 FT z-score: 948.9 E(): 0; 46.0% identity in 309 aa overlap. FT Contains Pfam match to entry PF00291 PALP, FT Pyridoxal-phosphate dependent enzyme and match to Prosite FT entry PS00165 Serine/threonine dehydratases FT pyridoxal-phosphate attachment site" FT /db_xref="GOA:Q9EWG3" FT /db_xref="HSSP:1TDJ" FT /db_xref="InterPro:IPR000634" FT /db_xref="UniProtKB/TrEMBL:Q9EWG3" FT /protein_id="CAD30948.1" FT /translation="MSYSTASCVAPVTLDDVRGAQKMLSGVARVTAMEGSRHLSQLVGS FT PVHLKCENLQRTGSFKLRGAYVRIAGLLPEQRAAGVVAASAGNHAQGVALASSLLGVRS FT TVFMPQGAPLPKISATRDYGAEVRLHGQVVDETLAAAQEYAERTGAVFIHPFDHPDVIA FT GQGTVGLEILEQCPEVRTVVVGIGGGGLAAGIAVAVKALRPDVRIVGVQAEGAAAYPPS FT LAAGRPVAVQNPATMADGIKVGRPGDVPFGIVGELVDEVRTVSEDALSTALLLCLERAK FT LVVEPAGASPVAALLSEPDAFEGPVVAVLSGGNVDPVLMQGVLRHGMAAQGRYLAVRLR FT LTDRPGALATLLGVLSVVDANVLDVSHVRTHPRLGLTEAEVELHLETKGPEHCTEVGRV FT LREAGYTVIA" FT misc_feature 26743..27612 FT /note="Pfam match to entry PF00291 PALP, FT Pyridoxal-phosphate dependent enzyme, score 254.90, E-value FT 1.1e-72" FT misc_feature 26827..26868 FT /note="PS00165 Serine/threonine dehydratases FT pyridoxal-phosphate attachment site" FT RBS 28054..28057 FT CDS 28064..29071 FT /transl_table=11 FT /gene="SCO4963" FT /gene_synonym="2SCK31.23" FT /product="putative ABC transporter ATP-binding protein" FT /note="2SCK31.23, possible ABC transporter ATP-binding FT protein, len: 335 aa; similar to TR:CAC08315 FT (EMBL:AL392149) Streptomyces coelicolor putative ABC FT transport system ATP-binding protein SCD19A.14, 336 aa; FT fasta scores: opt: 1211 z-score: 1254.5 E(): 0; 58.2% FT identity in 330 aa overlap. Contains Pfam match to entry FT PF00005 ABC_tran, ABC transporter and match to Prosite FT entry PS00017 ATP/GTP-binding site motif A (P-loop) and FT PS00211 ABC transporters family signature" FT /db_xref="GOA:Q9AD75" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9AD75" FT /protein_id="CAC21637.3" FT /translation="MPGAIYAEGLVKTFGDVRALDGVDLDVPEGTVLGLLGPNGAGKTT FT AVRCLTTLLRPDSGKAVVAGIDVLRQPNEVRRSIGLSGQFAAVDEYLTGRENLHMVGQL FT YQMKGKAAKARAAELLDQFHLSDAADRPTKTYSGGMRRRLDLAAALVVSPPVMFMDEPT FT TGLDPRNRQELWEVIKQLVAGGTTLLLTTQYLEEADHLAHDIAVVDHGRVIARGTSDQL FT KARTGGERVEVVVHDRGRMATASDVLAGFGKGSTTVEEHTRKLTVPVTGGAKLLAEVIR FT ELDVRGIEIDDIGLRRPTLDDVFLSLTGHVAEAADETNGSADDADHEQEKETAK" FT misc_feature 28151..28696 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 194.70, E-value 1.4e-54" FT misc_feature 28172..28195 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 28469..28513 FT /note="PS00211 ABC transporters family signature" FT RBS 29054..29059 FT CDS 29068..29925 FT /transl_table=11 FT /gene="SCO4964" FT /gene_synonym="2SCK31.24" FT /product="putative integral membrane transport protein" FT /note="2SCK31.24, probable integral membrane transport FT protein, len: 285 aa; similar to TR:AAG32069 FT (EMBL:AF317791) Streptomyces viridochromogenes hydrophobic FT transmembrane protein AviABCII, 265 aa; fasta scores: opt: FT 677 z-score: 786.2 E(): 0; 39.7% identity in 262 aa FT overlap. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="GOA:Q9ADK3" FT /db_xref="InterPro:IPR013525" FT /db_xref="UniProtKB/TrEMBL:Q9ADK3" FT /protein_id="CAD30949.1" FT /translation="MSAATDAAPVTASANPIGQSVRDSLVIARRNLIRMTRIPEMVLFG FT IIQPVMFVILFTYVFGGSIKVGSTTDSDVYKDFLMAGIFAQTVTFATAGSAAGIADDMQ FT KGLVDRFRSLPMARGAVLTGRTVADLVQTSITLLVLAIVALLVGWRTGSAEPTNIGRVL FT AGFGLLLLLGYAFTWIGALIGLSVRTPEAATSGGIIWLFPVTFVSNAFVDPTQMTPWLR FT HVAEWNPFSAVVQACRELFGNPGVVQSDAWPMQHPVWATLTYSIVIVLIFRTLAVRKYR FT RAAG" FT stem_loop complement(29968..30014) FT /note="possible stem loop. Score 56: 20/21 (95%) matches, 0 FT gaps" FT CDS complement(30027..30524) FT /transl_table=11 FT /gene="SCO4965" FT /gene_synonym="2SCK31.25c" FT /product="putative transcription elongation factor" FT /note="2SCK31.25c, probable transcription elongation FT factor, len: 165 aa; similar to SW:GREA_ECOLI (EMBL:X54718) FT Escherichia coli transcription elongation factor GreA FT (transcript cleavage factor), 158 aa; fasta scores: opt: FT 265 z-score: 326.5 E(): 1.2e-10; 34.0% identity in 153 aa FT overlap. Contains Pfam match to entry PF01272 GreA_GreB, FT Prokaryotic transcription elongation factor, GreA/GreB and FT match to Prosite entry PS00830 Prokaryotic transcription FT elongation factors signature 2" FT /db_xref="GOA:Q9ADK2" FT /db_xref="HSSP:1GRJ" FT /db_xref="InterPro:IPR018151" FT /db_xref="UniProtKB/Swiss-Prot:Q9ADK2" FT /protein_id="CAD30950.1" FT /translation="MTQTSENVTWLTQEAYNKLKEELEYLTGPARTEISAKIAAAREEG FT DLRENGGYHAAKEEQGKQELRVRQLTQLLESAKVGEAPAADGVVAPGMVVTIAFDGDED FT DTLTFLLASREYASSDIETYSPQSPLGSGVLGHKVGDDAQYELPNGKPASVRILKAEPY FT NG" FT misc_feature complement(30036..30509) FT /note="Pfam match to entry PF01272 GreA_GreB, Prokaryotic FT transcription elongation factor, GreA/GreB, score 171.50, FT E-value 1.4e-47" FT misc_feature complement(30102..30152) FT /note="PS00830 Prokaryotic transcription elongation factors FT signature 2" FT RBS complement(30532..30535) FT CDS complement(30705..31103) FT /transl_table=11 FT /gene="SCO4966" FT /gene_synonym="2SCK31.26c" FT /product="putative membrane protein" FT /note="2SCK31.26c, possible membrane protein, len: 132 aa; FT similar to TR:O53429 (EMBL:AL021897) Mycobacterium FT tuberculosis hypothetical 15.4 kDa protein MTV017.34c, 144 FT aa; fasta scores: opt: 186 z-score: 240.5 E(): 7.4e-06; FT 27.9% identity in 136 aa overlap. Contains possible FT hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9ADK1" FT /protein_id="CAD30951.1" FT /translation="MSTASTRTPQGRYGRSSDEQADRTLKIVGAVLGALLLALIGWFGY FT HYVGQNKISGELIGFELAEDSVQVHLEVRKDAGVTGYCTVRSQAEDGDEVGRADFRFDG FT DDTRIDKVVTLRTKAAGTTAELLGCHPE" FT RBS complement(31110..31113) FT RBS 31222..31225 FT CDS 31234..32115 FT /transl_table=11 FT /gene="SCO4967" FT /gene_synonym="2SCK31.27" FT /product="conserved hypothetical protein" FT /note="2SCK31.27, conserved hypothetical protein, len: 293 FT aa; highly similar to TR:O53430 (EMBL:AL021897) FT Mycobacterium tuberculosis hypothetical 32.7 kDa protein FT MTV017.35, 288 aa; fasta scores: opt: 992 z-score: 1173.4 FT E(): 0; 52.3% identity in 287 aa overlap" FT /db_xref="HSSP:1UAN" FT /db_xref="InterPro:IPR017811" FT /db_xref="UniProtKB/TrEMBL:Q9ADK0" FT /protein_id="CAD30952.1" FT /translation="MTDQLRLMAVHAHPDDESSKGAATMAKYVSEGVDVLVVTCTGGER FT GSILNPKLQGDAYIEENIHEVRRKEMDEAREILGVGQEWLGFVDSGLPEGDPLPPLPEG FT CFALEDVDKAAGELVRKIRSFRPQVITTYDENGGYPHPDHIMTHKITMVAFEGAADTEK FT YPESEYGTAYQPLKVYYNQGFNRPRTEALHHALLDRGLESPYEDWLKRWSEFERKERTL FT TTHVPCADFFEIRDKALIAHATQIDPEGGWFRVPMEIQKEVWPTEEYELAKSLVETSLP FT EDDLFAGIRDNA" FT CDS 32117..32344 FT /transl_table=11 FT /gene="SCO4968" FT /gene_synonym="2SCK31.28" FT /product="putative membrane protein" FT /note="2SCK31.28, possible membrane protein, len: 75 aa. FT Contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9EWG4" FT /protein_id="CAD30953.1" FT /translation="MSASASLAMTHLVTLAELDEDKVTPGVLGFIVFAVMALAVWGLMK FT SMNRHMGKVDFKEPAEQDASAGPEAKPQRG" FT CDS complement(32381..35884) FT /transl_table=11 FT /gene="SCO4969" FT /gene_synonym="2SCK31.29c" FT /product="putative regulatory protein" FT /note="2SCK31.29c, possible regulatory protein, len: 1167 FT aa; similar in its middle domain to SW:AFSR_STRCO FT (EMBL:D90155) Streptomyces coelicolor regulatory protein FT AfsR, 993 aa; fasta scores: opt: 298 z-score: 279.4 E(): FT 5e-08; 28.9% identity in 806 aa overlap. Contains 5x Pfam FT matches to entry PF00515 TPR, TPR Domain" FT /db_xref="GOA:Q9EWG5" FT /db_xref="InterPro:IPR000767" FT /db_xref="UniProtKB/TrEMBL:Q9EWG5" FT /protein_id="CAD30954.1" FT /translation="MGLLPSQISGCGHRGQERNSSIFPAGADPPPQGLLVAGHLTRAQP FT GKDPGMGRKGPWDAWGHGGARGDPAGHRCRRRGRDMRDSHRAEAEGLLRRAVEEEVRRS FT GGRTDGNVLLSRARAALDAMAGTAGEEYSAYTHALDEAAAGQLTFRQRYAREGAGTPLL FT VAAVAAVAAAVADVALGTGTGTAVGAGVTVGVVGAAATVVKVVGAHVPAAHHRAGAVSQ FT PGGPEQLRLQWLTALEVRGIRPFLDQQRMLAASTGPAKTGPKLRGADKSAAARGRSALE FT QSFGQLPEPGDAFAGRRAEMARLRQWVQAARASTETKPTVVVLHGAPGSGRTTLAVRAV FT HELRDYFRGACLVDLRGAGSAAGGSTAGGGGSGGPGPAGSVEGGESPLSTRDALLHLLN FT RLGAPREQLLFRERSSADQQVKRLSELYHQHLTGVPVTVVLDDASDPEQVCTLVPERSD FT SLVLVTARQALRLPPDLPARVYDLPVEALDAAGAEELLGAAAEDASGPYDAESSEQIRQ FT LCGGLPLALRVAGSSLGPRSPRALATDLAAYGPVEPVERALWLRYTDQSEPARRLLRRL FT ALAGRTSLGAAAAAALLATDETEANRQLAALSRAGLLDHVRGSRYRLHDVVRAFARARL FT ADEEEPGERTAAQERLIANYAELADSVLRLVDGNMSTRSNQFGQYGFTSLDEALRWLDD FT ESSFITATLRHAEGVDQGTVLNLLGALCDYCLLRGDLYRLGEISELAQSVDQGLLVRSV FT QWRTGIAARQLGELDKARTTLASVVDLYRDAHHDAGAARALCSLGITLHHQGNLTDAAA FT KLQEALGLQAAPELATDRAWTLHALAAVQRDRARLAEALELLTESLVLHRAGESVHGQA FT WAHFQLGQLHLRMGDVPGAESDLRVALDLYGRTQDARGEAWALTQLARARLVDGDVSAA FT VEGLRRAETRHRENADARGKAWSIYYLGQALEETGALDQSVRALERSRTMFSRMRDVYG FT LACARHHSARVTRDQRAAQTGSLRNSGFARQLLVDARADFQRIGVGHGEAWTCLELAVV FT DAGNARTPQALALCDEAAALFAGYGDRRGEDWARFLRCTLLPYAAPGGVEIGTAVAQEE FT LTQLSRARHPARDTKLDDYVDAYQLLLERGVQLEAGWQAWRLGMVPGRQAREVMGVAVT FT A" FT misc_feature complement(32933..33034) FT /note="Pfam match to entry PF00515 TPR, TPR Domain, score FT 5.30, E-value 13" FT misc_feature complement(33053..33154) FT /note="Pfam match to entry PF00515 TPR, TPR Domain, score FT 7.10, E-value 8.3" FT misc_feature complement(33173..33274) FT /note="Pfam match to entry PF00515 TPR, TPR Domain, score FT 13.90, E-value 1.5" FT misc_feature complement(33293..33394) FT /note="Pfam match to entry PF00515 TPR, TPR Domain, score FT 3.40, E-value 20" FT misc_feature complement(33413..33514) FT /note="Pfam match to entry PF00515 TPR, TPR Domain, score FT 17.00, E-value 0.45" FT misc_feature complement(34732..34820) FT /note="High G+C content region (89.88%)" FT CDS complement(35887..36039) FT /transl_table=11 FT /gene="SCO4970" FT /gene_synonym="2SCK31.30c" FT /product="hypothetical protein 2SCK31.30c" FT /note="2SCK31.30c, unknown, len: 50 aa" FT /db_xref="UniProtKB/TrEMBL:Q9EWG6" FT /protein_id="CAD30955.1" FT /translation="MKEKPGMCHTGAQRNGVSAAVRDPARNPHGAAGEATQVRVGAHLP FT VASCR" FT CDS 36195..37688 FT /transl_table=11 FT /gene="SCO4971" FT /gene_synonym="2SCK31.31" FT /product="putative dehydrogenase" FT /note="2SCK31.31, possible dehydrogenase, len: 497 aa; FT similar to N-terminal domain of SW:XDH_MOUSE (EMBL:X75129) FT Mus musculus xanthine dehydrogenase/oxidase Xdh, 1335 aa; FT fasta scores: opt: 345 z-score: 361.7 E(): 1.3e-12 31.5% FT identity in 483 aa overlap and to TR:O54050 (EMBL:AJ001013) FT Rhodobacter capsulatus xanthine dehydrogenase (EC FT 1.1.1.204) XdhA, 462 aa; fasta scores: opt: 631 z-score: FT 669.1 E(): 9.8e-30; 38.2% identity in 495 aa overlap. FT Contains Pfam matches to entries PF00111 fer2, 2Fe-2S FT iron-sulfur cluster binding domains, PF01799 fer2_2, FT [2Fe-2S] binding domain and PF00941 dehydrog_molyb, FT Molybdopterin binding domain in dehydrogenase and match to FT Prosite entry PS00197 2Fe-2S ferredoxins, iron-sulfur FT binding region signature" FT /db_xref="GOA:Q9EWG7" FT /db_xref="HSSP:1FO4" FT /db_xref="InterPro:IPR016169" FT /db_xref="UniProtKB/TrEMBL:Q9EWG7" FT /protein_id="CAD30956.1" FT /translation="MVTARITVNGKESPIAPAAPHTTVLDFLRERGLTGTKEGCAEGEC FT GACSVLVARPGVNKPTDWVPVNACLVPVAALDGQEVVTSEGLATVEAPGTPPVLHPVQE FT EMAVRGGSQCGYCTPGFVCSMAAEYYRPDRCAHADPGPDATAAADGAEGGDAEHGPNGF FT DLHALSGNLCRCTGYRPIRDAAFAVGTPTDEDPLARRREQDPPAPVATEYRQDDSAFLR FT RSTLAETLRLLRERPQAVVVAGSTDWGVEVNIRSRRADCVVAVDRLPELRDLRVESDHV FT EIGAALTLTEIERRLDGSVPLLAQLFPQFASRLIRNGATLGGNLGTGSPIGDSPPVLLA FT LEASLVLADADGEREVPLADYFTGYRQSVRRPGELIRAVRVPLPLSPVTAFHKIAKRRF FT DDISSLAVAFALDVEGGTVRKARIGLGGVAATPVRALATEAALEGRPWTTGTAEAAAEV FT LRGEGTPMSDHRASARYRAAMLGQSLLKLYAQTTEAVPS" FT misc_feature 36204..36419 FT /note="Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur FT cluster binding domains, score 37.80, E-value 2.6e-07" FT misc_feature 36312..36338 FT /note="PS00197 2Fe-2S ferredoxins, iron-sulfur binding FT region signature" FT misc_feature 36441..36755 FT /note="Pfam match to entry PF01799 fer2_2, [2Fe-2S] binding FT domain, score 80.70, E-value 3.1e-20" FT misc_feature 36834..37682 FT /note="Pfam match to entry PF00941 dehydrog_molyb, FT Molybdopterin binding domain in dehydrogenase, score FT 220.00, E-value 3.6e-62" FT RBS 37671..37674 FT CDS 37685..40105 FT /transl_table=11 FT /gene="SCO4972" FT /gene_synonym="2SCK31.32" FT /product="putative dehydrogenase" FT /note="2SCK31.32, possible dehydrogenase, len: 806 aa; FT similar to the C-terminal region of SW:XDH_MOUSE FT (EMBL:X75129) Mus musculus xanthine dehydrogenase/oxidase FT Xdh, 1335 aa; fasta scores: opt: 1456 z-score: 1610.8 E(): FT 0; 43.3% identity in 767 aa overlap. Contains Pfam match to FT entry PF01315 Ald_Xan_dh_C, Aldehyde oxidase and xanthine FT dehydrogenase, C terminus" FT /db_xref="GOA:Q9EWG8" FT /db_xref="HSSP:1FIQ" FT /db_xref="InterPro:IPR014309" FT /db_xref="UniProtKB/TrEMBL:Q9EWG8" FT /protein_id="CAD30957.1" FT /translation="MSHLSERPEKPVVGVSMPHESAVQHVTGAALYTDDLVQRTKDVLH FT AYPVQVMKARGRVTALRTGAALAVPGVVRVLTGADVPGVNDAGMKHDEPLFPDEVMFHG FT HAVAWVLGETLEAARIGAAAVEVDLEELPSVITLQDAIAADSYHGARPVMTHGDVDAGF FT ADSAHVFTGEFQFSGQEHFYLETHAALAQVDENGQVFIQSSTQHPSETQEIVSHVLGVP FT AHEVTVQCLRMGGGFGGKEMQPHGFAAIAALGAKLTGRPVRFRLNRTQDLTMSGKRHGF FT HATWKIGFDTEGRIQALDATLTADGGWSLDLSEPVLARALCHIDNTYWIPNARVAGRIA FT RTNTVSNTAFRGFGGPQGMLVIEDILGRCAPRLGVDAKELRERNFYRPGQGQTTPYGQP FT VTQPERIAAVWQQVQDNGHIADREREIAAFNAAHPHTKRALAVTGVKFGISFNLTAFNQ FT GGALVLIYKDGSVLINHGGTEMGQGLHTKMLQVAATTLGIPLHKVRLAPTRTDKVPNTS FT ATAASSGADLNGGAVKNACEQLRERLLRVAASQLGTNASDVRIVEGVARSLGSDQELAW FT DDLVRTAYFQRVQLSAAGYYRTEGLHWDAKSFRGSPFKYFAIGAAATEVEVDGFTGAYR FT IRRVDIVHDVGDSLSPLIDIGQVEGGFVQGAGWLTLEDLRWDTGDGPNRGRLLTQAAST FT YKLPSFSEMPEEFNVTLLENATEEGAVFGSKAVGEPPLMLAFSVREALRQAAAAFGPRG FT TAVELASPATPEAVYWAIESARQGGTAGDGRTHGAAASDAVAVRTGVEALSGA" FT misc_feature 37763..39796 FT /note="Pfam match to entry PF01315 Ald_Xan_dh_C, Aldehyde FT oxidase and xanthine dehydrogenase, C terminus, score FT 826.40, E-value 2.5e-249" FT CDS 40107..40928 FT /transl_table=11 FT /gene="SCO4973" FT /gene_synonym="2SCK31.33" FT /product="conserved hypothetical protein" FT /note="2SCK31.33, conserved hypothetical protein, len: 273 FT aa; similar to TR:Q9RYX5 (EMBL:AE001862) Deinococcus FT radiodurans conserved hypothetical protein DRA0179, 274 aa; FT fasta scores: opt: 888 z-score: 1076.8 E(): 0; 52.4% FT identity in 271 aa overlap" FT /db_xref="GOA:Q9EWG9" FT /db_xref="InterPro:IPR014308" FT /db_xref="UniProtKB/TrEMBL:Q9EWG9" FT /protein_id="CAD30958.1" FT /translation="MTWIAAVARLRARREPGVLVTVATVRGHAPRDAGAKLVVGRTGTW FT GSIGGGNVEAVAVDRAREMIAAAAPEPEMLDFALNDKVTNRHGVQCCGGTVAVLLEPLP FT VVRAVAVFGVGHVGLELARILARQDIDLHLVDSRAELLTEERLGVLSDAVAQVHTHHTP FT LLPEEVLAELPPGTHVLIMTHDHAEDAALCDAALRTDHLGSIGLIGSAAKWARFRKRLA FT GEGDHDDALIDRIKTPIGLADITGKEPATIAVSVAADLLRTFEADFEADRP" FT RBS 41110..41115 FT CDS 41121..41624 FT /transl_table=11 FT /gene="SCO4974" FT /gene_synonym="2SCK31.34" FT /product="putative deaminase" FT /note="2SCK31.34, possible deaminase, len: 167 aa; similar FT to TR:AAG05887 (EMBL:AE004677) Pseudomonas aeruginosa FT probable deaminase PA2499, 151 aa; fasta scores: opt: 299 FT z-score: 372.9 E(): 3.1e-13; 36.6% identity in 123 aa FT overlap. Contains Pfam match to entry PF00383 FT dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase FT zinc-binding region" FT /db_xref="GOA:Q9ADJ9" FT /db_xref="InterPro:IPR002125" FT /db_xref="UniProtKB/TrEMBL:Q9ADJ9" FT /protein_id="CAD30959.1" FT /translation="MTTDTLETGIREFERAWMDKAIELATTSVRNGGGPFGALIAKGGE FT IVALGNNQVTAGLDPTAHAEVSAIRAACKALDTFSLEGCTLVTSCEPCPMCLSSALWAR FT VDRLVFSADRHDAAVAGFDDRKFYDLFEKRPQANWPMTVEHLDLPHRTQPFDAWIAKTD FT RVDY" FT misc_feature 41205..41444 FT /note="Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine FT and deoxycytidylate deaminase zinc-binding region, score FT 92.90, E-value 6.4e-24" FT CDS 41702..43762 FT /transl_table=11 FT /gene="SCO4975" FT /gene_synonym="2SCK31.35" FT /product="conserved hypothetical protein" FT /note="2SCK31.35, conserved hypothetical protein, len: 680 FT aa; similar to SW:YYAL_BACSU (EMBL:D26185) Bacillus FT subtilis hypothetical 78.8 kDa protein in TetB-ExoA FT intergenic region YyaL, 689 aa; fasta scores: opt: 1541 FT z-score: 1751.9 E(): 0; 39.2% identity in 683 aa overlap. FT Contains match to Prosite entry PS00133 Zinc FT carboxypeptidases, zinc-binding region 2 signature" FT /db_xref="GOA:Q9EWH0" FT /db_xref="InterPro:IPR012335" FT /db_xref="UniProtKB/TrEMBL:Q9EWH0" FT /protein_id="CAD30960.1" FT /translation="MRKDGGMPNRLAQATSPYLLQHAENPVDWWPWEAEAFEEARRRGV FT PVLLSVGYSACHWCHVMAHESFEDGPTAEYLNSHFVSVKVDREERPDVDAVYMEAVQAA FT TGQGGWPMTVFLTPDAEPFYFGTYFPPEPRHGMPSFRQVLQGVQQAWAERRDEVDEVAG FT KIVRDLAGREISYGDAEAPGEEQLGQALLGLTREYDERRGGFGGAPKFPPSMVIEFLLR FT HHARTGAEGALQMAADTCERMARGGIYDQLGGGFARYSVDREWVVPHFEKMLYDNALLC FT RVYAHLWRATGSDLARRVALETADFMVRELRTAEGGFASALDADSDDGTGKHVEGAHYV FT WTPAQLTEVLGAEDAELAAQYFGVTQEGTFEHGASVLQLPQQESVFDAARIASVRERLL FT AARDGRPAPGRDDKVVAAWNGLAVAALAETGAYFERPDLVEAAVAAADLLVRLHLDEQV FT RLTRTSKDGRAGANAGVLEDYADVAEGFLALASVTGEGVWLDFAGFLLDHVLTRFTDES FT GSLYDTAADAERLIRRPQDPTDNATPSGWSAAAGALLSYAAHTGSAPHRAAAERALGVV FT KALGPRVPRFIGWGLAAAEALLDGPREVAVVAPDPADPAARGLHRTALLGTAPGAVVAF FT GTEGSDEFPLLADRPLVGGAPAAYVCRNFTCDAPTTDPDRLRTALGVAPTG" FT RBS 41714..41718 FT misc_feature 41765..41797 FT /note="PS00133 Zinc carboxypeptidases, zinc-binding region FT 2 signature" FT CDS complement(43773..44501) FT /transl_table=11 FT /gene="SCO4976" FT /gene_synonym="2SCK31.36c" FT /product="conserved hypothetical protein" FT /note="2SCK31.36c, conserved hypothetical protein, len: 242 FT aa; similar to TR:O53776 (EMBL:AL021942) Mycobacterium FT tuberculosis hypothetical 28.5 kDa protein MTV039.17, 252 FT aa; fasta scores: opt: 509 z-score: 573.9 E(): 2e-24; 42.3% FT identity in 241 aa overlap. Contains Pfam match to entry FT PF01927 DUF82, Protein of unknown function DUF82" FT /db_xref="InterPro:IPR002782" FT /db_xref="UniProtKB/TrEMBL:Q9EWH1" FT /protein_id="CAD30961.1" FT /translation="MNGPEIHVEFAPELHLFVPRARPTGVASAATDGVSTLGHLVESLG FT VPLTEVGALLVDGREVPPGHIPAGGESVRVRPVRHPQRVPGAPLRFLLDVHLGTLARRL FT RLLGVDTAYESTDLGDPALAALSAAEKRVLLSRDRGLLRRRELWAGAYVYSTRPEEQLQ FT EVLDRFRPALSPWTRCTACNGLLRTATKEEVAEQLEGGTRRSYDVFAQCTACGRAYWRG FT AHHEQLEAIVERAVSSTRDA" FT misc_feature complement(43791..44237) FT /note="Pfam match to entry PF01927 DUF82, Protein of FT unknown function DUF82, score 137.90, E-value 1.9e-37" FT CDS complement(44535..45242) FT /transl_table=11 FT /gene="SCO4977" FT /gene_synonym="2SCK31.37c" FT /product="putative tetR-family transcriptional regulator" FT /note="2SCK31.37c, probable tetR-family transcriptional FT regulator, len: 235 aa; similar to SW:TCMR_STRGA FT (EMBL:M80674) Streptomyces glaucescens tetracenomycin C FT transcriptional repressor TcmR, 226 aa; fasta scores: opt: FT 304 z-score: 354.3 E(): 3.4e-12; 37.2% identity in 218 aa FT overlap. Contains Pfam match to entry PF00440 tetR, FT Bacterial regulatory proteins, tetR family and possible FT helix-turn-helix motif at residues 46..67 (+5.26 SD)" FT /db_xref="GOA:Q9EWH2" FT /db_xref="InterPro:IPR012287" FT /db_xref="PDB:2OF7" FT /db_xref="UniProtKB/TrEMBL:Q9EWH2" FT /protein_id="CAD30962.1" FT /translation="MTAARSAPSPAGAPRPGLRERKKTRTREAIRAATYGLIRQQGYEA FT TTVEQIAERAEVSPSTVLRYFPTREDIVLTDEYDPVMAAELAARPAGEPWSDSLRHVLR FT KALGLGAGEEAELIRLRTRLLAEVPAVRARMLENMSDTGRMLARAIADRTGLDPDGLEV FT RIVSMSLVGGLMEVSRYWAEHDHEESLAELVDRALDALENGLPALRESDRESDREGDRG FT GHREDRREGPRKD" FT misc_feature complement(45021..45155) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 53.00, E-value FT 3.9e-12" FT CDS complement(45297..46001) FT /transl_table=11 FT /gene="SCO4978" FT /gene_synonym="2SCK36.01c" FT /product="putative integral membrane protein" FT /note="2SCK36.01c, conserved hypothetical membrane protein, FT len: 234 aa; similar to SW:YA85_MYCTU (EMBL:AL021897) FT Mycobacterium tuberculosis hypothetical 26.0 kDa protein FT RV1085c or MTV017.38c, 242 aa; fasta scores: opt: 563 FT Z-score: 653.6 bits: 128.3 E(): 8.6e-29; 39.524% identity FT in 210 aa overlap. Contains possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q93JL6" FT /db_xref="InterPro:IPR005744" FT /db_xref="UniProtKB/TrEMBL:Q93JL6" FT /protein_id="CAC40591.1" FT /translation="MTASVPDAPRDLPAGGRGPVTLSLPHPVKPKLRGWLHLGMFPAVL FT VAGLVLTALAETSEARIACGVYVLTACLLFGVSALYHRGDWSPRMDGVLRRLDHANIFL FT IIAGTYTPLTMLLLPGAKGEWLLWGIWAAAAAGIVFRVFWVGAPRWLYTPCYLAMGWAA FT VFYLPEFMRAGGVAVLVLVIVGGLLYSAGGVIYGLKRPNPSPRWFGFHEVFHSFTLAAF FT IAHYVGISLVAY" FT RBS 46278..46282 FT CDS 46288..48117 FT /transl_table=11 FT /gene="SCO4979" FT /gene_synonym="2SCK36.02" FT /product="putative phosphoenolpyruvate carboxykinase" FT /note="2SCK36.02, probable phosphoenolpyruvate FT carboxykinase, len: 609 aa; similar to SW:PPCK_CHLLI FT (EMBL:S56812) Chlorobium limicola phosphoenolpyruvate FT carboxykinase [GTP] (EC 4.1.1.32) PckA, 646 aa; fasta FT scores: opt: 2400 Z-score: 2689.0 bits: 507.7 E(): FT 3.6e-142; 58.361% identity in 598 aa overlap. Contains Pfam FT match to entry PF00821 PEPCK, Phosphoenolpyruvate FT carboxykinase and match to Prosite entry PS00505 FT Phosphoenolpyruvate carboxykinase (GTP) signature" FT /db_xref="GOA:Q93JL5" FT /db_xref="HSSP:1KHB" FT /db_xref="InterPro:IPR008210" FT /db_xref="UniProtKB/Swiss-Prot:Q93JL5" FT /protein_id="CAC40592.1" FT /translation="MARDIAAPPVPTNHQELISWVNEIAELTQPDAVVWCDGSEAEYER FT LCGELVEKGTFRKLDPIKRPNSYYAASDPTDVARVEDRTFICSAKEEDAGPTNHWKDPA FT EMRAIFTGDKGEGGLFRGSMRGRTMYVVPFCMGPLGSPLSALGVEITDSAYVAASMRTM FT TRMGQPVLDELGDEGFFVKAVHSVGAPLEPGQADVPWPCNSTKYISHFPEDREIWSYGS FT GYGGNALLGKKCYALRIASVMARDEGWLAEHMLVLKLTPPTGAPKYVAAAFPSACGKTN FT LAMLEPTISGWTVETIGDDIAWMRFGEDGRLYAINPEAGFFGVAPGTGEHTNANAMKTL FT WGNSVFTNVALTDDGDVWWEGMTEETPAHLTDWKGNDWTPESGTPAAHPNARFTTPAAQ FT CPIIAPEWEDPRGVPISAILFGGRRATAVPLVTESFDWNHGVFLGANVASEKTAAAEGK FT VGELRRDPFAMLPFCGYNMGDYMGHWVDVAKDKDQSKLPKIYYVNWFRKDDAGRFVWPG FT FGENGRVLKWIVERLEGRADGVETPIGVLPTKESLDTDGLDLADADLEFLLSVDKEVWR FT EEAALVPEHLNTFGDHTPAELWDQYRALVRRLG" FT misc_feature 46342..48111 FT /note="Pfam match to entry PF00821 PEPCK, FT Phosphoenolpyruvate carboxykinase, score 1344.70, E-value FT 0" FT misc_feature 47104..47130 FT /note="PS00505 Phosphoenolpyruvate carboxykinase (GTP) FT signature" FT CDS complement(48400..49350) FT /transl_table=11 FT /gene="SCO4980" FT /gene_synonym="2SCK36.03c" FT /product="hypothetical protein 2SCK36.03c" FT /note="2SCK36.03c, unknown, len: 316 aa" FT /db_xref="UniProtKB/TrEMBL:Q93JL4" FT /protein_id="CAC40593.1" FT /translation="MSGDGLEGLLAAVHRLTAQRMGPPVCGTAGHGTGHVCLVPPAGAG FT LPGIEEAIGSRFGEPLRLVTGTTTEAAGGSAGLPLRTPFGERIVEMRAWAYGDRWIGCG FT TVRADDADGAVRPVVLVAERADPAAGASAPATWVDGIVAVTGWETARARAVDWPAVEAR FT LGTPLPGDYKRLVEIFGGAGAFDGYLQLQVPDAHDRSTDLVRHTEWLGEWARTHGSRLW FT EPYPVYPAPGGLLQWASTEQADGFYWLTGDPDPDRWPVLAKEDVPDSWERFDGPTGEFV FT HRMLTEPDHPFSTARWFDVHWYQDYGPAAADEGRV" FT CDS complement(49347..50747) FT /transl_table=11 FT /gene="SCO4981" FT /gene_synonym="2SCK36.04c" FT /product="putative bifunctional protein" FT /note="2SCK36.04c, possible bifunctional protein, len: 466 FT aa; N-terminal region presents low similarity to N-terminal FT region of TR:O14362 (EMBL:Z97992) Schizosaccharomyces pombe FT putative glucan synthase-1 (EC 2.4.1.34) SPBC30D10.17c, 504 FT aa; fasta scores: opt: 176 Z-score: 188.3 bits: 44.3 E(): FT 0.0071; 24.931% identity in 361 aa overlap and C-terminal FT region to C-terminal region of TR:AAK22951 (EMBL:AE005774) FT Caulobacter crescentus oxidoreductase, GFO/IDH/MOCA family FT CC0967, 307 aa; fasta scores: opt: 146 Z-score: 160.2 bits: FT 38.4 E(): 0.26; 26.590% identity in 173 aa overlap" FT /db_xref="InterPro:IPR018958" FT /db_xref="UniProtKB/TrEMBL:Q93JL3" FT /protein_id="CAC40594.1" FT /translation="MSSIHDFATWEPLLRLVRASHPERLAGPGGHVMGQIGLGGWSVPV FT RRPHPAPGRASLVEDMQDEFTAVEAVQAALRAHGRQSVSFMVETRVDGRTALHVVDSGP FT AVEHGLVSPFVGTLVLVEGAVPEPWRRLPEAVPGALPAPSADPALLERTLRERLPDAVG FT ATEAEIAEAQTRLGVTLPDELKALYRVVRARWQDWRGDYAAQERVVDAVGCELLPLDQL FT YVADARSRPCLWQFAATDAAVTAPDAAVQGLVGSPGWIAFGDNGGGDRLALDLTPGPGG FT HTGQVVMIGHEDSIGAGLLAESLTDMVVNGRAEWHPGRDWDRPPVVARLNVLGDDVSAV FT ARPELEVLVLGGREGEPRSLAPLAGLPRLRTLHACPGALADPLEIAGLTRLEYLRLGPE FT EWRVLLDAGAVPRSLLAAHIEVRGEHHPPRIIALANELLSLWDRPLISRTVLEGDLDTD FT RTAQGGAR" FT RBS complement(50755..50758) FT RBS 50923..50929 FT CDS 50938..51120 FT /transl_table=11 FT /gene="SCO4982" FT /gene_synonym="2SCK36.05" FT /product="putative membrane protein" FT /note="2SCK36.05, putative membrane protein, len: 60 aa. FT Contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q93JL2" FT /protein_id="CAC40595.1" FT /translation="MADGGDFYSRDRPREPDPQLREDRPRGGGPEDPHQRGNWPVWAIV FT LAIILVFVVLTVIFG" FT CDS complement(51206..51628) FT /transl_table=11 FT /gene="SCO4983" FT /gene_synonym="2SCK36.06c" FT /product="hypothetical protein 2SCK36.06c" FT /note="2SCK36.06c, unknown, len: 140 aa" FT /db_xref="UniProtKB/TrEMBL:Q93JL1" FT /protein_id="CAC40596.1" FT /translation="MYEPIRSKSVHSTMAGTTTDFPGRSRDDELDIQLAGHLAALLAVT FT DELRALAPDTGLDAAAERLAEQVTRLRGGQAPVRLQVAATRQEPRPAALHRRAHTLAAR FT ALVVAASRADTAVAILTAERMDAHSAALEPRPLASR" FT RBS complement(51635..51641) FT CDS complement(51700..52911) FT /transl_table=11 FT /gene="SCO4984" FT /gene_synonym="2SCK36.07c" FT /product="putative aminotransferase" FT /note="2SCK36.07c, probable aminotransferase, len: 403 aa; FT similar to many, e.g. TR:O86587 (EMBL:AL031514) FT Streptomyces coelicolor putative aminotransferase FT SC2H4.04c, 402 aa; fasta scores: opt: 1881 Z-score: 2193.7 FT bits: 414.8 E(): 1.4e-114; 65.920% identity in 402 aa FT overlap. Contains Pfam match to entry PF00155 aminotran_1, FT Aminotransferase class-I" FT /db_xref="GOA:Q93JL0" FT /db_xref="HSSP:5BJ4" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:Q93JL0" FT /protein_id="CAC40597.1" FT /translation="MQVIQSTKLANVCYEIRGPVLEEAMRLEAAGHRILKLNTGNPAAF FT GFECPPEILEDILRNVSTAHGYGDAKGLLAARRAVVMHNQTLGIETDVEHVFIGNGVSE FT LIVMAMQGLLDDGDEVLVPAPDYPLWTAAVSLSGGTAVHYRCDEQSDWMPDLADVERKI FT TDRTKALVIINPNNPTGAVYDDAMLRGLTDIARRHNLLVCSDEIYDKILYDDATHTPTA FT AIAPDLLTLTFNGMSKAYRVAGYRVGWMSISGPRAHAESYIEGLTILANMRLCANMPGQ FT HGVVAALSGRQTINELVLPGGRLREQRDAAHEALTSIPGVTCVKPKGALYLFPRLDPKV FT FKIKDDRRMVLDLLRQEKIMVVQGTGFNWPEPDHFRVVTLPTAADLREAVDRIGNFLDG FT YSQP" FT misc_feature complement(51715..52896) FT /note="Pfam match to entry PF00155 aminotran_1, FT Aminotransferase class-I, score 99.70, E-value 5.7e-26" FT CDS 53145..53999 FT /transl_table=11 FT /gene="SCO4985" FT /gene_synonym="2SCK36.08" FT /product="hypothetical protein 2SCK36.08" FT /note="2SCK36.08, unknown, len: 284 aa" FT /db_xref="GOA:Q93JK9" FT /db_xref="UniProtKB/TrEMBL:Q93JK9" FT /protein_id="CAC40598.1" FT /translation="MNKPLLAALATLAVTGVGVAPAAASPAAPAASASPAAPAVRAVSF FT AGTVALSNCSGSVVRLPASEDDDPALVMSNGHCLETGFPAAGEVVVDQPSSRTFGLLNA FT SGTRVGTLRAGKIAYATMTDTDVSLYQLTSTYAQIRGSYGISPLTLDDTRPTAGTAITV FT VSGYWKRTYACNVDGFAYRLKEGEWTWKDSVRYTSACRTIGGTSGSPVVDNATGKVVAV FT NNTGNEDGGRCTDNNPCEVAEDGTVTVREGINYGQQTYRIPACFALDNKLDLSRSGCAL FT PKP" FT CDS complement(54037..55647) FT /transl_table=11 FT /gene="SCO4986" FT /gene_synonym="2SCK36.09c" FT /product="putative D-aminoacylase" FT /note="2SCK36.09c, probable D-aminoacylase, len: 536 aa; FT similar to SW:NDAD_ALCXX (EMBL:S80683) Alcaligenes FT xylosoxydans D-aminoacylase (EC 3.5.1.81) Dan, 483 aa; FT fasta scores: opt: 370 Z-score: 413.6 bits: 86.1 E(): FT 2e-15; 33.647% identity in 532 aa overlap" FT /db_xref="GOA:Q93JK8" FT /db_xref="HSSP:1M7J" FT /db_xref="InterPro:IPR012855" FT /db_xref="UniProtKB/TrEMBL:Q93JK8" FT /protein_id="CAC40599.1" FT /translation="MEELVIRDADVVDGSGGDSYRADVVVDGGRIVSIVKEAAAAGCQR FT PEARRELDAEGLVLSPGFIDMHAHSDLALLRDPDHSAKAAQGVTLEVIGQDGLSYAPVD FT DRTLGEVRRAIAGWNGHGDDVDFDWRSVGEYLDRLDRGIAVNAAYLIPQGTVRALAVGW FT DDREATEAELEHMRRLVAEGLEQGAVGLSSGLTYTPGMYAKDAELTELCRVVASYGGYY FT CPHHRSYGAGALKAYEEMVELTREAGCPLHLAHATMNFGVNKGKAPELLTLLDEALAGG FT ADITLDTYPYTPGCTTLVALLPSWASEGGPEQILKRLADDDTAERIRHHMEVIGSDGSH FT GVPMEWETIEISGTGDPALAEYVGRTVLESARLRGESPWTVARHLLLADRLAPTILQHV FT GHEENVRAIMRHRVHTGGSDGILQGAKPHPRAYGTFPHYLGHYVRELGVLPLEECVAHL FT TSRPAARLRLPDRGLVREGYRADLVLFDPATVAAGSSFDEPRVLPTGIPYVLVDGRFVM FT EDGRRTDVLAGRSVRRVPR" FT RBS complement(55656..55661) FT CDS complement(55676..56977) FT /transl_table=11 FT /gene="SCO4987" FT /gene_synonym="2SCK36.10c" FT /product="putative D-amino acid deaminase" FT /note="2SCK36.10c, possible D-amino acid deaminase, len: FT 433 aa; similar to TR:Q45085 (EMBL:AF158699) Burkholderia FT cepacia D-serine deaminase Dsd, 432 aa; fasta scores: opt: FT 919 Z-score: 1026.2 bits: 199.0 E(): 1.5e-49; 41.259% FT identity in 429 aa overlap. Contains match to Prosite entry FT PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="UniProtKB/TrEMBL:Q93JK7" FT /protein_id="CAC40600.1" FT /translation="MALDNGPAGGREALAELAEERVDHRFKGLPPDAYGLTLAELAGQR FT RNLFTGGFTTPVLALSAERLEHNLKLMETYSARHGLAFAPHGKTSMAPQLFHRQIEHGA FT WGITLAVPHQVRVARAFGVQRVFLANELVDAAALRWISAELDADPGFRFVCYADSVRGV FT ELMDAALTDAGAARPLDVVVELAAGAGARTGVRTEAGCAAVADAVAGARTLRLAGVAGY FT EGEVPDADPERVHAWLRRLVALAVDFDRAGRFDGLEEIVLSAGGSAWFDAVADVFAEVP FT GLSLPVLKLLRSGAYVSHDDGHYRELTPFNRVPEEGALEPAFRLWSQVVSRPSPEQAFT FT NAGKRDAAYDLHLPFAQVVRPADGGPERPATGVEVTGLSDQHAWLRTSGEADLAVGDWV FT GAGLSHPCTSFDKWQLIPVAQADGTVVDYIRTFF" FT misc_feature complement(56711..56734) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(56982..56986) FT RBS 57098..57102 FT CDS 57114..58169 FT /transl_table=11 FT /gene="SCO4988" FT /gene_synonym="2SCK36.11" FT /product="putative carbohydrate kinase" FT /note="2SCK36.11, probable carbohydrate kinase, len: 351 FT aa; similar to TR:Q9K6K5 (EMBL:AP001519) Bacillus FT halodurans 2-keto-3-deoxygluconate kinase (EC 2.7.1.45) FT KdgK or BH3724, 317 aa; fasta scores: opt: 578 Z-score: FT 638.8 bits: 126.5 E(): 5.7e-28; 38.835% identity in 309 aa FT overlap. Contains Pfam match to entry PF00294 pfkB, pfkB FT family carbohydrate kinase" FT /db_xref="GOA:Q93JK6" FT /db_xref="HSSP:1J5V" FT /db_xref="InterPro:IPR011611" FT /db_xref="UniProtKB/TrEMBL:Q93JK6" FT /protein_id="CAC40601.1" FT /translation="MTVDGPRSTAPDVVDVVALGESMVTFLPSRPGRLADVPSFDRAIG FT GAESNVACVLAAAGHSARWAGRVGADGFGDHLVEAIGAYGVDVSAVRRDPARPTGVYFR FT TAGDRATDAHEVAYYRAGSAASAMSVDTMDLDAIRSGRVLHLSGITPALSAGCLGLMRE FT LTARRPGRPLVSFDVNHRPGLWRDARHGHGPEVLLELARGADLVFVGDDEARDAWGLGG FT PEAVRAALPEPELLVVKQGASGATAFHGTDATSVPALHVDVVAAVGAGDAFAAGFLSAT FT LRGKPVRERLRHGHLWAAAALTVPADLAAPPARGHADRLVALDDTAWGRLRLGPGWTHA FT EEGAEEEVRTP" FT misc_feature 57150..58055 FT /note="Pfam match to entry PF00294 pfkB, pfkB family FT carbohydrate kinase, score 194.20, E-value 2.1e-54" FT RBS 58150..58156 FT CDS 58166..58930 FT /transl_table=11 FT /gene="SCO4989" FT /gene_synonym="2SCK36.12" FT /product="putative IclR-family transcriptional regulatory FT protein" FT /note="2SCK36.12, probable IclR-family transcriptional FT regulatory protein, len: 254 aa; similar to SW:KDGR_ECOLI FT (EMBL:AE000277) Escherichia coli transcriptional regulator FT KdgR, 263 aa; fasta scores: opt: 420 Z-score: 488.7 bits: FT 98.0 E(): 1.3e-19; 30.992% identity in 242 aa overlap. FT Contains Pfam match to entry PF01614 IclR, Bacterial FT transcriptional regulator and possible helix-turn-helix FT motif at residues 20..41 (+3.12 SD)" FT /db_xref="GOA:Q93JK5" FT /db_xref="HSSP:1MKM" FT /db_xref="InterPro:IPR005471" FT /db_xref="UniProtKB/TrEMBL:Q93JK5" FT /protein_id="CAC40602.1" FT /translation="MSQTVDRALSILPLLAEGPADLGRVADRLGVHKSTALRLLRTLHD FT HGFVYRQSDQRYRLGARLISLAQEAMENLDVREIAHPHLVRLNEQVGHTVHLAVHEEDE FT VLYIDKVESRYPVRMYSRIGKPVAITVAAVAKLLLADLPEDERRAVAEQLDYPMYTARS FT TPNADGFLKELAKVREQGWATDLGGHEESINCVAAPIRGADGRVVAAMSVSAPNVVVTA FT DELLTLLPLVRRTADAISGEYSGRTPVKEVTA" FT misc_feature 58334..58891 FT /note="Pfam match to entry PF01614 IclR, Bacterial FT transcriptional regulator, score 203.80, E-value 2.5e-57" FT RBS 58913..58917 FT CDS 58927..59337 FT /transl_table=11 FT /gene="SCO4990" FT /gene_synonym="2SCK36.13" FT /product="conserved hypothetical protein" FT /note="2SCK36.13, conserved hypothetical protein, len: 136 FT aa; similar to SW:YABJ_BACSU (EMBL:D26185) Bacillus FT subtilis putative regulator of purine biosynthesis YabJ, FT 124 aa; fasta scores: opt: 239 Z-score: 301.4 bits: 61.4 FT E(): 3.5e-09; 36.641% identity in 131 aa overlap. Contains FT Pfam match to entry PF01042 UPF0076, YjgF family" FT /db_xref="HSSP:1QD9" FT /db_xref="InterPro:IPR006175" FT /db_xref="UniProtKB/TrEMBL:Q93JK4" FT /protein_id="CAC40603.1" FT /translation="MTDKIALVPATHTVPPAKFSHGVKKGNILQVAGQVGFLPHEEGKA FT PTPAGPTLREQTLQTLANVKAILEEGGASWDDVMMLRVYLTDVDHFAEMNEIYNAYFAE FT QGLTQPPAARTTVYVGLPAGLLIEIDALAVLG" FT misc_feature 58957..59331 FT /note="Pfam match to entry PF01042 UPF0076, YjgF family, FT score 98.90, E-value 1e-25" FT CDS 59458..60936 FT /transl_table=11 FT /gene="SCO4991" FT /gene_synonym="2SCK36.14" FT /product="putative sugar transport integral membrane FT protein" FT /note="2SCK36.14, probable sugar transport integral FT membrane protein, len: 492 aa; similar to SW:GNTP_BACSU FT (EMBL:J02584) Bacillus subtilis gluconate permease GntP, FT 448 aa; fasta scores: opt: 988 Z-score: 1028.7 bits: 199.7 FT E(): 1.1e-49; 39.186% identity in 467 aa overlap. Contains FT Pfam match to entry PF02447 GntP_permease, GntP family FT permease and match to Prosite entry PS00017 ATP/GTP-binding FT site motif A (P-loop). Also contains possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q93JK3" FT /db_xref="InterPro:IPR003474" FT /db_xref="UniProtKB/TrEMBL:Q93JK3" FT /protein_id="CAC40604.1" FT /translation="MSYSSLRLAAAEAPPHTGGLLTLIDGTAGLLTVAAIGIALLLFLI FT IKVRLQPFVALLAVSIAVGLLAGLSVTELFGTVQKSDAVSTIESGMGGILGHVAIIIGL FT GTMLGAILEVSGGAQVLASRLLGLFGEKRAPLAMGLTGLIFGIPVFFDVGIFVLAPIVY FT AAAKRSGKSILLYCLPLLAGLSMTHAFLPPHPGPVAAAGLLNVKLGWIILMGIVCGIPA FT VLAAWVFSAWIGRRIFVPVPQDMVEASEEAKQAVIEEQRKAGVAPNESPVALGTVLGII FT GTPLVLILAATFSSIALDPSTLRSVIEFFGNPFVALTIALLLAYYLLGIRRGWSRKSLE FT TVSTASLKPVGNILLVVGAGGVFGAVLKASGVAQALSDTFNDVGLPVIVLAYLISVVLR FT VAQGSATVAIVTTAGIVAPLLAEGDHSQAFVALVIMAISAGSIFASHVNDGGFWMVAKY FT FGISERDTLKTWTVLESVLSVAGFVVAAVVSLFV" FT misc_feature 59542..60930 FT /note="Pfam match to entry PF02447 GntP_permease, GntP FT family permease, score 514.40, E-value 8.3e-151" FT misc_feature 59950..59973 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 61032..61676 FT /transl_table=11 FT /gene="SCO4992" FT /gene_synonym="2SCK36.15" FT /product="hypothetical protein 2SCK36.15" FT /note="2SCK36.15, unknown, len: 214 aa. High content of FT alanine and glutamic amino acid residues in C-terminal FT region" FT /db_xref="UniProtKB/TrEMBL:Q93JK2" FT /protein_id="CAC40605.1" FT /translation="MEQRRGSTSQPLEGAGFDPAFIPGLTAPVSGEPEDVRRAEDEAEK FT DADAETEESSHSPAADEPPAEDAEDAEEPDAEAPVDGPVFEASDRRAKIVADHRGVRLS FT LDDQACEFRWDEVGAVETETGRFGKRFTVTVHTPDRRWYPIEIEAASRSRFAEWESALD FT EVLDAYFEDGEAESETEAEAVEAAETADTADTAEKDAEDAEGAEEAKARAE" FT misc_feature 61551..61673 FT /note="high concentration of alanine and glutamic amino FT acid residues" FT CDS 61696..63066 FT /transl_table=11 FT /gene="SCO4993" FT /gene_synonym="2SCK36.16" FT /product="putative metal ion transport protein" FT /note="2SCK36.16, possible metal ion transport protein, FT len: 456 aa; similar to SW:MNTH_SALTY (EMBL:AF161317) FT Salmonella typhimurium manganese transport protein MntH, FT 413 aa; fasta scores: opt: 241 Z-score: 273.7 bits: 59.8 FT E(): 1.2e-07; 20.824% identity in 437 aa overlap. Contains FT possible hydrophobic membrane spanning regions" FT /db_xref="GOA:Q93JK1" FT /db_xref="InterPro:IPR001046" FT /db_xref="UniProtKB/TrEMBL:Q93JK1" FT /protein_id="CAC40606.1" FT /translation="MHALLSHRRPWAFLTPMADTTGNTSDAGVSVGADQAPRKSSWRYI FT GPGIVVAATGVGAGDLVATLIAGSNFGYTLLWAAVIGCLVKISLAEACGRWHLATGRTL FT FDGWASIGSWTTWFFAIYAVIWGFVYGAAAMSSSALPLQALFPDVMDLEWWGIACGLVG FT LVFVWFNKYNVFEKVMTVLVGVMFVITVYLAIRVTPNLGDAFAGLLPVLPDEKDSVLNT FT LGLIGGVGGTITLAAYGYWVNAKGWTTTGWMKVMRLDNRVAYATTGIFVVAMLLVGAEL FT LHSANIAIASGDKGLIQLGDILEQEYGTATGKLFLIGFFATSFTSLIGVWHGVSLMFAD FT FLARRRGEREARGDELASGRRERSWAFRAYLLWLTFPPMILLFQDEPFRLIIIYGVLGA FT AFMPFLALTLMWLLNSSRTPREWRNGSLSNGMLAMAGLLFLVLCVKQIWDQPWSEFF" FT CDS 63210..64163 FT /transl_table=11 FT /gene="SCO4994" FT /gene_synonym="2SCK36.17" FT /product="hypothetical protein 2SCK36.17" FT /note="2SCK36.17, unknown, len: 317 aa" FT /db_xref="UniProtKB/TrEMBL:Q93JK0" FT /protein_id="CAC40607.1" FT /translation="MRGHDRQSDHELTGRRSAGDRGPVVRTDRAASTAGQAWSAGDLSP FT HAVSDLQNSAGNAAVAASLAGQRQQHGSQPPVQRMFQKMKNAVSGNRSAAQQEVNVRVG FT EDDIPMTRQGAFYVFRTPQGGRAYIHDVAVVNGVLNDDLTPHVMKYRMGGLALYRGIPR FT HHETWHDVNGGGVIPPLGSGELPDYATNNTSFIPFSPSERVARGSAVATRGMAERNRAE FT YVQGYSRSNENFFVGLVATVVAGPNLDVGFFNGGEVQIRGPVHGFETDHIRMGTDVQEA FT LTGTPGDPREPISENRPNTPNEEQKKEFEKEHGMLP" FT CDS complement(64218..65480) FT /transl_table=11 FT /gene="SCO4995" FT /gene_synonym="2SCK36.18c" FT /product="putative membrane protein" FT /note="2SCK36.18c, putative membrane protein, len: 420 aa. FT Contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q93JJ9" FT /protein_id="CAC40608.1" FT /translation="MLENERQDPFEDRLGTALRDAGDGFEADRAALVTAGRARGRRALL FT RRRAAVVGGVAGVALAGVGGVLVLPADHPAGPDRSGTASAPSAGDATTAAASFTGDDLL FT HELKGLLPPGTYGEESARGSDHQLGPTAQLVYDDGAGAAAIGMGFARVEPGSAQVRELM FT ACPDHNITPYDDCSSDRLPDGSLLKLYQGYEYPDLRVDTKRWTADLVTAEGQHVSVSEW FT NSPAEKGAPVSREEPPLSTERLRELVTAGVWREVVDAVPKSRKPPRSAAPRTERPEVSG FT KSVGDTLAALLPRKLDVVSRGGQESEYAYVVVDDGRGRSLVQINVQHGMADVAGQLYAD FT GETLPDGTRVATRQGPGEKAGSGVVMWTVDTLRPGPAGFRVVISAFNTGDQNKDATRDA FT PALTMEQLRKIALSGEWDRLR" FT CDS complement(65560..66069) FT /transl_table=11 FT /gene="SCO4996" FT /gene_synonym="2SCK36.19c" FT /product="putative RNA polymerase ECF sigma factor" FT /note="2SCK36.19c, probable RNA polymerase ECF sigma FT factor, len: 169 aa; similar to SW:RPOE_STRCO (EMBL:L29636) FT Streptomyces coelicolor RNA polymerase sigma-E factor SigE FT or SCE94.07, 176 aa; fasta scores: opt: 278 Z-score: 347.2 FT bits: 70.7 E(): 9.9e-12; 36.527% identity in 167 aa FT overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, FT Sigma-70 factor (ECF subfamily)" FT /db_xref="GOA:Q93JJ8" FT /db_xref="InterPro:IPR007627" FT /db_xref="UniProtKB/TrEMBL:Q93JJ8" FT /protein_id="CAC40609.1" FT /translation="MRQGRADEYAEFAVARAGHLYRSACLLTAGDTHLAEDLVQETFGR FT LYVRWGRVSRAENPAAYAQTVLTRAFLAHQRRRSSGERATDVFPDLPGAGDGDASLRLT FT LLDALARLPAKDRAVVVLRYWDDRSVEQTADVLGVSSAAVRTRCSRALGRLRELLGEDL FT SEYARP" FT misc_feature complement(65836..66003) FT /note="Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 FT factor (ECF subfamily), score 14.20, E-value 0.0028" FT CDS complement(66168..66359) FT /transl_table=11 FT /gene="SCO4997" FT /gene_synonym="2SCK36.20c" FT /product="hypothetical protein" FT /note="2SCK36.20c, hypothetical protein, len: 63 aa; FT similar to TR:Q9F3E1 (EMBL:AL450289) Streptomyces FT coelicolor putative AbaA-like protein SC2H2.14, 89 aa; FT fasta scores: opt: 96 Z-score: 150.9 bits: 31.9 E(): 0.86; FT 32.787% identity in 61 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q93JJ7" FT /protein_id="CAC40610.1" FT /translation="MDDITWEEPFCGEGASCFRLGTDATGNAYVAIAGAEDAALTDSRE FT ALRRMILDIKAGKADHLL" FT RBS complement(66367..66371) FT CDS complement(66371..67222) FT /transl_table=11 FT /gene="SCO4998" FT /gene_synonym="2SCK36.21c" FT /product="conserved hypothetical protein" FT /note="2SCK36.21c, hypothetical protein, len: 283 aa; FT similar to TR:Q9XD96 (EMBL:AF106004) Streptomyces FT coelicolor hypothetical 31.8 kDa protein ORF3, 283 aa; FT fasta scores: opt: 815 Z-score: 959.3 bits: 185.4 E(): FT 8e-46; 45.230% identity in 283 aa overlap. Contains Pfam FT match to entry PF01381 HTH_3, Helix-turn-helix" FT /db_xref="GOA:Q93JJ6" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q93JJ6" FT /protein_id="CAC40611.1" FT /translation="MPPRTTPTERQRRLGAELRKMRTAAGITADQAAGLLGLDRAKVSN FT IETGIRTISPERLRTLACNCDCSDEAYVEALVRMARPGARGWWERYRGSLSAGLLDIAE FT FEAQATRMRTIHIAHIPGLLQTSDHALELFRAVLPLLPEHEVALRLAYRVERQRVLEGD FT DPPEYVAVVHEAAVRMQFGGPTVARAQLEHLVAVSERPTVRLLVVPFTAGAFPGSGQIF FT NYLEGPVPQLDTVQIDSTHGPEFLSGEAQLAKYRTHLDRMERIALSPQASRDFIRDVAN FT GL" FT misc_feature complement(67007..67171) FT /note="Pfam match to entry PF01381 HTH_3, Helix-turn-helix, FT score 36.30, E-value 6.9e-07" FT RBS complement(67228..67232) FT RBS 67425..67429 FT CDS 67435..67923 FT /transl_table=11 FT /gene="SCO4999" FT /gene_synonym="SCK15.01" FT /product="hypothetical protein SCK15.01" FT /note="SCK15.01, hypothetical protein, len: 162 aa; similar FT to TR:CAB7697 (EMBL:AL159178) Streptomyces coelicolor FT hypothetical 16.8 kD protein SCH22A.02c, 160 aa; fasta FT scores: opt: 133 z-score: 165.9 E(): 0.09; 28.9% identity FT in 142 aa overlap" FT /db_xref="InterPro:IPR017690" FT /db_xref="UniProtKB/TrEMBL:Q9KYA3" FT /protein_id="CAB92592.1" FT /translation="MPTTRCPAAPTYPADPTPPIPETLAYSLTLPAALASAALARATTR FT EVLRAHGLTDMLDPALQAVGELTAVASQFTESSNYYLTLRYRFSTLRLIAYDSHPRHTS FT PHLATACDTRRRAALRVLACVCRACDGTWGFGEAREPGGGTRMWATLPRASAAAYGAS" FT CDS 68306..68614 FT /transl_table=11 FT /gene="SCO5000" FT /gene_synonym="SCK15.02" FT /product="conserved hypothetical protein" FT /note="SCK15.02, conserved hypothetical protein, len: 102 FT aa; similar to TR:CAB77311 (EMBL:AL160312) Streptomyces FT coelicolor hypothetical 11.3 kD protein SCD35.27c, 101 aa; FT fasta scores: opt: 465 z-score: 578.9 E(): 9e-25; 72.6% FT identity in 95 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9KYA2" FT /protein_id="CAB92593.1" FT /translation="MSFLKFAEAEVKDMAAKLETSGGHMKSASKEMKSADTKQVGHSGL FT ESACDDFADSWDYGFGQLSKITKGVSKFANKAAEEFAELDQKLYDELRKAREEKGEK" FT RBS 68333..68336 FT RBS 68603..68607 FT CDS 68611..69252 FT /transl_table=11 FT /gene="SCO5001" FT /gene_synonym="SCK15.03" FT /product="putative integral membrane protein" FT /note="SCK15.03, possible integral membrane protein, len: FT 213 aa; similar to TR:CAB77310 (EMBL:AL160312) Streptomyces FT coelicolor putative integral membrane protein SCD35.26, 198 FT aa; fasta scores: opt: 349 z-score: 424.5 E(): 3.6e-16; FT 37.4% identity in 182 aa overlap. Contains possible FT hydrophobic membrane spanning regions at C-terminal domain" FT /db_xref="InterPro:IPR017871" FT /db_xref="UniProtKB/TrEMBL:Q9KYA1" FT /protein_id="CAB92594.1" FT /translation="MSLRRHLGKLLRATGEDGRPSGSAHAPGSSGETVASFTTEVPWPS FT LRKFAQFAYIAEQYGYRYSGLDPDLRDSGTPFFVFRRLPDAGERAARTRGSFPGAPENG FT RLPGMRAWPLPVLTLPAARSEVKLLLARIVVDYYGALGRQRMRPWLIGIPVVFLLFLLV FT NGELHATGLRVAAGMAVALIVVLTASRVFMRRRRATYRRLLERSGLGPPP" FT CDS complement(69185..69835) FT /transl_table=11 FT /gene="SCO5002" FT /gene_synonym="SCK15.04c" FT /product="conserved hypothetical protein" FT /note="SCK15.04c, conserved hypothetical protein, len: 216 FT aa; similar to TR:CAB77308 (EMBL:AL160312) Streptomyces FT coelicolor hypothetical 26.0 kD protein SCD35.24c, 241 aa; FT fasta scores: opt: 613 z-score: 732.4 E(): 0; 52.8% FT identity in 197 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9KYA0" FT /protein_id="CAB92595.1" FT /translation="MPGADALERVQSAERMRHSLPMFLDRDDTLVDIAMCLGAERVRDE FT DKLSYGLLVVSVRPSGHDDRLLAAEGIYRAKERLFFTREAEVEELDFALGKGGRGQQDM FT LLAAKLPGGPGVMSASLRTVELRTAGQAASGGEDAAAQKIPMAVLQLICPAPRDYCTYI FT TIATPSVYLLDSYTERLAHIGRTFVFEAPTPLTEAGRAPTAQAAAGTSHGDGA" FT misc_feature complement(69862..71812) FT /note="previously sequenced fragment EMBL:AB017008 FT Streptomyces coelicolor gene for ChiA, partial cds." FT CDS complement(69963..71678) FT /transl_table=11 FT /gene="SCO5003" FT /gene_synonym="chiA" FT /gene_synonym="SCK15.05c" FT /product="chinitase A precursor" FT /note="SCK15.05c, chiA, chinitase A precursor, len: 571 aa; FT identical to previously sequenced TR:Q9Z9M9 (EMBL:AB017008) FT Streptomyces coelicolor chinitase A precursor ChiA, 571 aa FT and to TR:Q59924 (EMBL:D13775) Streptomyces lividans FT chitinase A precursor (EC 3.2.1.14) ChiA, 571 aa. Contains FT Pfam match to entry PF02018 CBD_6, Cellulose binding FT domain, PF00041 fn3, Fibronectin type III domain, PF00704 FT Glyco_hydro_18, Glycosyl hydrolases family 18 and matches FT to Prosite entries PS00678 Trp-Asp (WD) repeats signature FT and PS01095 Chitinases family 18 active site. Contains also FT possible N-terminal region signal peptide sequence" FT /db_xref="GOA:Q9KY99" FT /db_xref="HSSP:1K85" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:Q9KY99" FT /protein_id="CAB92596.1" FT /translation="MDPVRRRSRGRRLGSLTGAVTAALALAFTAVGPASAADVNNAKNA FT GFESGLSNWACSANSGTTVASPAHAGSAALKATPAGQDNARCSQSVAVKPNSTYTLSAW FT VQGGYSYLGVTGTGTTDVSTWTPDSTAWKQLKTTFSTGSSTTSVSVYTHGWYGQAAYYV FT DDLSVFGPDGGGGDGGNPDPTVPSAPAGLSVSGTTPNSASLSWNTVSGATGYNVYRDGT FT KVTAVTGTSATVTGLAASTSYSFQVTATNAAGESVKSAAVTARTTAPDDGGNGGDLPKH FT AVTGYWQNFNNGATVQKISDVPSAYDIIAVAFADATTTPGAVTFNLDSAGLGGYTVDQF FT KADVRAKQAAGKKVIISVGGEKGTVSVNSSASATNFANSVYSVMREYGFDGVDIDLENG FT LNPTYMTQALRALSAKAGPDMILTMAPQTIDMQSTQGGYFQTALNVKDILTVVNMQYYN FT SGTMLGCDGKVYAQGTVDFLTALACIQLEGGLAPSQVGLGLPASTRAAGGGYVSPSVVN FT AALDCLTKATNCGSFKPSKTYPDLRGAMTWSTNWDATAGNAWSNSVGAHVHALP" FT misc_feature complement(70488..70514) FT /note="PS01095 Chitinases family 18 active site" FT misc_feature complement(70494..70580) FT /note="Pfam match to entry PF00704 Glyco_hydro_18, Glycosyl FT hydrolases family 18, score 19.40, E-value 3.7e-05" FT misc_feature complement(70902..71123) FT /note="Pfam match to entry PF00041 fn3, Fibronectin type FT III domain, score 64.00, E-value 3.1e-15" FT misc_feature complement(71055..71099) FT /note="PS00678 Trp-Asp (WD) repeats signature" FT misc_feature complement(71166..71564) FT /note="Pfam match to entry PF02018 CBD_6, Cellulose binding FT domain, score 101.70, E-value 1.5e-26" FT CDS 71997..72938 FT /transl_table=11 FT /gene="SCO5004" FT /gene_synonym="SCK15.06" FT /product="hypothetical protein SCK15.06" FT /note="SCK15.06, unknown, len: 313 aa. Contains hydrohilic FT C-terminall region" FT /db_xref="UniProtKB/TrEMBL:Q9KY98" FT /protein_id="CAB92597.1" FT /translation="MGDGEPRVPTAIAVTSADLALPPQDERTLPAAVLQDVDRRPLESV FT LAELQTLVDQCGHVIVVCSQAVPASVERRLHTVRALLETDRIALFRPPLPPLGIAVLAR FT QLRQLASCDLSPGVLASAGRLLTHYIHAGALLGSVARLDHVPVGLKAHARSWVPGSQFG FT VVAHPVPQLVRIGPEAALAGPEFGTWLLVAKGQHPTDWVTGSLAPSWHVQGLRETALPA FT ESATWWGTGRLTEFCAYLPDLSVLYQLVTSVRRGTCHWCGIDVIGDRCVFCSATPPVYD FT DGGAGGGGRDRALAPRRDPALGRRRERRALTG" FT CDS 73213..73824 FT /transl_table=11 FT /gene="SCO5005" FT /gene_synonym="SCK15.07" FT /product="hypothetical proten SCK15.07" FT /note="SCK15.07, unknown, len: 203 aa" FT /db_xref="InterPro:IPR013974" FT /db_xref="UniProtKB/TrEMBL:Q9KY97" FT /protein_id="CAB92598.1" FT /translation="MKSKVGPEVTAYRVKSDIEPYTELGATQFEKVEMPERWLSENAVT FT DLSRVRGKIAVTTLKAGSLLQTDMIVDTPALRPGQQEVAIMIDAATGVAGKITPGSTVN FT VYATFEGPREGDPDQSKIIVTGAKVIDVGELTSLEPDEDSRDREPTDAVPITFALSTID FT AQRITYAESFARRVRLALVAPGGDTTVPDKDRTYELAKDK" FT CDS 73832..75088 FT /transl_table=11 FT /gene="SCO5006" FT /gene_synonym="minD1" FT /gene_synonym="SCK15.08" FT /product="putative septum site-determining protein" FT /note="SCK15.08, minD1, possible septum site-determining FT protein, len: 418 aa; N-terminal domain similar to FT TR:Q9RZD9 (EMBL:AE001862) Deinococcus radiodurans FT DNA-binding response regulator DRA0010, 211 aa; blastp FT scores: Score = 103 (36.3 bits), Expect = 0.0045, FT Identities = 50/194 (25%), Positives = 85/194 (43%) and FT C-terminal domain highly similar to TR:Q9ZF15 FT (EMBL:AJ005576) Streptomyces griseus septum FT site-determining protein MinD protein, 396 aa; fasta FT scores: opt: 1230 z-score: 1302.8 E(): 0; 70.5% identity in FT 281 aa overlap. Contains Pfam matches to entries PF00072 FT response_reg, Response regulator receiver domain and FT PF00991 ParA, ParA family ATPase" FT /db_xref="GOA:Q9KY96" FT /db_xref="InterPro:IPR001789" FT /db_xref="UniProtKB/TrEMBL:Q9KY96" FT /protein_id="CAB92599.1" FT /translation="MATRILPAVGDPDAVRSLTTLLSQLPEAEPVAPVTDSTQLVDTLA FT RLAAESVDELPEVVIVHERIGPVPALELIREVALRFPAVGVILVTSDPGPGLFQAAMDH FT GARGLVALPLGYEELASRVQAVAQWSAGVRRHLGGAVDVFTGTGGTVVTVSGAKGGVGA FT TLTAVQLALAAQASGRSTALLDMDLQTGDVASYLDVQFRRSVADLAAITDLSPRVLADA FT VFRHDSGLALLLAPGEGERGEEITDRAARQIVGALRSRYEVVVVDCGAQLGGAGAAAVE FT SADTALLVTTPDVVAVRGAKRAVRMWERLQIRKAAETTVVVNRHTRGTEIQPPLIQKIT FT GTAIAATTVPANFKELQGAVDAGRVHELDGRSTVKQALWALAGELGLAGVPDAGRKGHG FT RLKGDRGASGFRRRKDGAG" FT misc_feature 73838..74200 FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 1.30, E-value 0.0034" FT misc_feature 74504..74827 FT /note="Pfam match to entry PF00991 ParA, ParA family FT ATPase, score 47.60, E-value 2.7e-10" FT CDS 75085..75480 FT /transl_table=11 FT /gene="SCO5007" FT /gene_synonym="minD2" FT /gene_synonym="SCK15.09" FT /product="putative septum site-determining protein" FT /note="SCK15.09, minD2, possible septum site-determining FT protein, len: 131 aa; similar to C-terminal domain of FT TR:Q9ZF15 (EMBL:AJ005576) Streptomyces griseus septum FT site-determining protein MinD protein, 396 aa; fasta FT scores: opt: 360 z-score: 444.6 E(): 2.7e-17; 47.3% FT identity in 129 aa overlap and to Streptomyces coelicolor FT septum site-determining protein minD3 SCK15.10, 131 aa; FT fasta scores: opt: 177 z-score: 196.8 E(): 2.1e-05; 35.8% FT identity in 109 aa overlap. Contains possible hydrophobic FT membrane spanning region and TTA leucine codon, possible FT target for bldA regulation" FT /db_xref="InterPro:IPR012495" FT /db_xref="UniProtKB/TrEMBL:Q9KY95" FT /protein_id="CAB92600.1" FT /translation="MSGLRGRDRARDGGQVTIEFLGMTPVIIATLVVLWQLVLVGYTYT FT LAGNAADEAVRAATAAERGARQGACREAGLDKLPGSWEGGASVGCDAAGGFVTADVRIE FT VPLLFPGTLSLPFTVHGHAGAVEEEDD" FT misc_feature 75094..75096 FT /gene="none" FT /note="TTA leucine codon. Possible target for bldA FT regulation" FT repeat_region 75109..75147 FT /note="2x degenerate repeat: RA(G/R)D(R/G)GQV(A/T)IE(Y/F)L" FT RBS 75468..75473 FT CDS 75482..75877 FT /transl_table=11 FT /gene="SCO5008" FT /gene_synonym="minD3" FT /gene_synonym="SCK15.10" FT /product="putative septum site-determining protein" FT /note="SCK15.10, minD3, possible septum site-determining FT protein, len: 131 aa; similar to TR:Q9ZF15 (EMBL:AJ005576) FT Streptomyces griseus septum site-determining protein MinD FT protein, 396 aa; fasta scores: opt: 180 z-score: 224.4 E(): FT 5e-05; 37.7% identity in 122 aa overlap and to Streptomyces FT coelicolor septum site-determining protein minD2, 131 aa; FT fasta scores: opt: 177 z-score: 189.4 E(): 5.4e-05; 36.4% FT identity in 107 aa overlap. Contains possible hydrophobic FT membrane spanning region" FT /db_xref="InterPro:IPR012495" FT /db_xref="UniProtKB/TrEMBL:Q9KY94" FT /protein_id="CAB92601.1" FT /translation="MPYSRRKKPTGTPYRRGARAGDRGQVAIEYLGFLPILVLVGMAAV FT QLGLIAYTAQQAGTAARAGARSASLRESAETACAAAVSSWLADGTDCPASYGGDEVTVT FT ATVEIPSIVPGWEFDPATRTATMPLDH" FT repeat_region 75536..75574 FT /note="2x degenerate repeat: RA(G/R)D(R/G)GQV(A/T)IE(Y/F)L" FT RBS 75881..75885 FT CDS 75896..77233 FT /transl_table=11 FT /gene="SCO5009" FT /gene_synonym="SCK15.11" FT /product="putative secretory protein" FT /note="SCK15.11, probable secretory protein, len: 445 aa; FT similar to TR:P94647 (EMBL:U77780) Chlorobium limicola FT secretory protein kinase Kbh, 474 aa; fasta scores: opt: FT 1192 z-score: 1311.8 E(): 0; 47.7% identity in 396 aa FT overlap, to SW:TRBB_AGRT6 (EMBL:U43675) Agrobacterium FT tumefaciens conjugal transfer protein TrbB, 323 aa; fasta FT scores: opt: 512 z-score: 568.9 E(): 3.2e-24; 30.4% FT identity in 326 aa overlap and to TR:Q9X921 (EMBL:AL035636) FT Streptomyces coelicolor putative secretory protein FT SCH5.19c, 523 aa; fasta scores: opt: 878 z-score: 847.4 FT E(): 0; 40.3% identity in 365 aa overlap. Contains Pfam FT match to entry PF00437 GSPII_E, Bacterial type II secretion FT system protein and match to Prosite entry PS00017 FT ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9KY93" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9KY93" FT /protein_id="CAB92602.1" FT /translation="MSLRARIHSPEEHGSRGEDGHLVASYRAKLLEEIDLAEMSALATA FT ERRARLERVLGHIISREGPVLSTVERSQLIRRVVDEALGLGILEPLLEDASITEIMVNG FT PDAIFVERAGRVEQLPLRFASHDQLMQTIERIVSTVNRRVDESNPMVDARLPSGERVNV FT IIPPLSLTGATLTIRRFPRSFTLQELIGLGSLDENMLYLLAGLVQARFNIIVSGATGTG FT KTTLLNALSGLIPESDRIITIEDSAELQLQQAHVIRLESRPPNVEGQGRITIRDLVRNS FT LRMRPDRIVVGEVRGGESLDMLQAMSTGHDGSLATVHANSAEDALMRLQTLASMSDVEI FT PFVALHDQINSSVDVLIQLTRFADGARRITEIALLASHGGEPYRLATVARFNARPMSAD FT GRVVGAYEYHPLPHRTAERLYMAGQPIPQAFGVAHTPDQLTTREAR" FT misc_feature 76532..76891 FT /note="Pfam match to entry PF00437 GSPII_E, Bacterial type FT II secretion system protein, score 64.70, E-value 1.7e-18" FT misc_feature 76544..76567 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 77243..78193 FT /transl_table=11 FT /gene="SCO5010" FT /gene_synonym="SCK15.12" FT /product="putative integral membrane protein" FT /note="SCK15.12, possible integral membrane protein, len: FT 316 aa; similar to TR:AAF40196 (EMBL:AF229646) Caulobacter FT crescentus hypothetical 34.6 kD protein, 325 aa; fasta FT scores: opt: 287 z-score: 328.2 E(): 8.2e-11; 21.9% FT identity in 315 aa overlap. Contains possible N-terminal FT region signal peptide sequence and possible hydrophobic FT membrane spanning regions" FT /db_xref="InterPro:IPR018076" FT /db_xref="UniProtKB/TrEMBL:Q9KY92" FT /protein_id="CAB92603.1" FT /translation="MEPELDTLVTLTTGVTLLTCVLAIVGLHSYAAGKAQRAALVDRLT FT ATGQAPSAGRRRRFPTLDRRLRRTGLGRNLERRLSATGLDVTPGEFFAYMLATVAGLWL FT IGQAALAPFFGPLAGLLGIGVAIQFLNWQRQKRIEKFINQLPELARILANATQAGLALR FT TAIGMAAEELEAPAGEELGKVADQLAIGASMDDALGELAGRLPSRELVVLVTTLVLSNR FT AGGQVVGALRNLTETLEERKETRREVRTQLSQVTMTSYAVPVLGIGSLLLMNGVKDGAL FT ERMTGSPAGQAAVITAFALYAVGFVLIRRLSRIDV" FT CDS 78213..79115 FT /transl_table=11 FT /gene="SCO5011" FT /gene_synonym="SCK15.13" FT /product="putative integral membrane protein" FT /note="SCK15.13, possible integral membrane protein, len: FT 300 aa; similar to TR:O27061 (EMBL:AE000871) FT Methanobacterium thermoautotrophicum conserved protein FT MTH980, 313 aa; fasta scores: opt: 235 z-score: 285.2 E(): FT 2e-08; 27.7% identity in 238 aa overlap. Contains possible FT N-terminal region signal peptide sequence and possible FT hydrophobic membrane spanning regions" FT /db_xref="InterPro:IPR018076" FT /db_xref="UniProtKB/TrEMBL:Q9KY91" FT /protein_id="CAB92604.1" FT /translation="MPPALPAVLLALLMALAVWGVFAGVRMYRAEAKLPDDLALALEVG FT ATRTGAAHSLIDRMGMRYAPAVLRLMGPALVARYRRRIDLAGNPGGLTIDRYAARRAVY FT GFLGALGFLVFLLRGQYLVALLLLAFGAFWTEAGIWSAIRIRKDVIERTLPDFLDVLAV FT VVSAGLGFRQALDRVSTRYEGPWADELRITLRQMDLGMSRREAFTELRRRNDSEQVAMF FT VTALQQGEELGAPIVDTLVSLAKDMRRTDAQNARRKAARAVPKATLMITTFMVPATMIL FT LGAGLILGSGTDFGTITGE" FT RBS 79365..79368 FT CDS 79378..79575 FT /transl_table=11 FT /gene="SCO5012" FT /gene_synonym="SCK15.14" FT /product="putative integral membrane protein" FT /note="SCK15.14, possible integral membrane protein, len: FT 65 aa; similar to some other integral membrane proteins, FT e.g. TR:AAF40189 (EMBL:AF229646) Caulobacter crescentus FT PilA, 59 aa; fasta scores: opt: 84 z-score: 142.8 E(): 1.8; FT 36.2% identity in 47 aa overlap. Contains possible FT hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9KY90" FT /protein_id="CAB92605.1" FT /translation="MTNWLHTAAAYLHTRLTTRHDKGQTAVEYLGIIAVVVAIVLAITG FT TDIGETIYNAITDKIDEVID" FT CDS 79578..80174 FT /transl_table=11 FT /gene="SCO5013" FT /gene_synonym="SCK15.15" FT /product="putative secreted protein" FT /note="SCK15.15, possible secreted protein, len: 198 aa. FT Contains possible N-terminal region signal peptide FT sequence. High content in alanine amino acid residues" FT /db_xref="UniProtKB/TrEMBL:Q9KY89" FT /protein_id="CAB92606.1" FT /translation="MYSSQRDAGQAFPIYITVVAGLLFLALAYFAVGQAATNRNGAQTA FT ADAAALAAAQETRDQLAGEWVDNLSDPASWERIFDGLGTGPSDSCWRASELAAQNDAQV FT DSCEPDGPLGFKVEVTSDDPVGDSIVPGTEDKHAQASATAVIEPNCEFELPDGDGKDDV FT LPRITCDDQDWELDPEDLPELPKPQDLFDVHLADS" FT RBS 80196..80199 FT CDS 80207..80785 FT /transl_table=11 FT /gene="SCO5014" FT /gene_synonym="SCK15.16" FT /product="putative secreted protein" FT /note="SCK15.16, possible secreted protein, len: 192 aa. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="UniProtKB/TrEMBL:Q9KY88" FT /protein_id="CAB92607.1" FT /translation="MGIRFAVKVRNGATGLTVAVGLALCVVGCSSGGGDDNKAEASASA FT TAGEQSDPTAQEGTDSPLAELKGEDGLLLTIDSAERDAGGFVTVSGEIKNDGAEAARVP FT IQTRGDETEIMRHGGSLGGATLVDPAKKKRYYVLRDTDGRPLTTTDMPRIKPGASIPVF FT MQFPAPPTDTGKVTFQLPTFASAPIEISG" FT CDS 80794..81405 FT /transl_table=11 FT /gene="SCO5015" FT /gene_synonym="SCK15.17" FT /product="putative secreted protein" FT /note="SCK15.17, possible secreted protein, len: 203 aa; FT similar to many other membrane proteins, e.g. TR:Q9S6B8 FT (EMBL:AF115336) Pseudomonas fluorescens major outer FT membrane protein OprF, 343 aa; fasta scores: opt: 247 FT z-score: 285.4 E(): 2e-08; 34.3% identity in 181 aa FT overlap. Contains Pfam match to entry PF00691 OmpA, OmpA FT family and possible N-terminal region signal peptide FT sequence" FT /db_xref="GOA:Q9KY87" FT /db_xref="InterPro:IPR006665" FT /db_xref="UniProtKB/TrEMBL:Q9KY87" FT /protein_id="CAB92608.1" FT /translation="MHNSRVAVLLTTSVLTAASVGVSQSYAADDPPGTEPSASAPVEVD FT PNDPDLKLPDGATLAQAKVLDIKSVVEEQSGDERREDTNTSVTLALQAEVLFGKDSSKL FT GAEAKSRIRGIADEIRTQNATRVRVFGFTDDLGSSAHGDVLSKRRANAVHDVLSQSLND FT AGITYEVRGYGEQYPIADNSTEAGRKKNRRVEVSFPRTEP" FT misc_feature 81079..81369 FT /note="Pfam match to entry PF00691 OmpA, OmpA family, score FT 77.70, E-value 2.4e-19" FT CDS complement(81503..82318) FT /transl_table=11 FT /gene="SCO5016" FT /gene_synonym="SCK15.18c" FT /product="putative integral membrane protein" FT /note="SCK15.18c, possible secreted protein, len: 271 aa. FT Contains possible N-terminal region signal peptide sequence FT and a repeat region: 7x AS at N-terminal domain" FT /db_xref="UniProtKB/TrEMBL:Q9KY86" FT /protein_id="CAB92609.1" FT /translation="MGEVAAVVSAITAVAGLLLAVFGIPLVGNSSPIGRSVADSGPTSG FT AAPAASHSTADAGSEGASASASASASASASGSSKVPSSTAPSGSAPTGQPPAGGDEPRS FT SASASSCSSSLPQGWRRVEVPALTVCFGRPGGWGEKPAGELQSSWGSPDGVYDLTVKRD FT RTYGTTARAASAGQLAWYRDTSESSMAGVEVTTHKTRQNGRDALWLEIDYHWEKQSAPR FT KRLEVFVAGKAGYVYQLLVDTEATSQRLAEQSRLFASARKNLLIDVSTG" FT repeat_region complement(82094..82135) FT /note="conserved repeat region translated in CDS SCK15.18c" FT CDS 82526..83623 FT /transl_table=11 FT /gene="SCO5017" FT /gene_synonym="SCK15.19" FT /product="putative araC family regulatory protein" FT /note="SCK15.19, possible araC family regulatory protein, FT len: 365 aa; similar to TR:Q54308 (EMBL:X86780) FT Streptomyces hygroscopicus helix-turn-helix DNA-binding FT protein, 330 aa; fasta scores: opt: 247 z-score: 294.6 E(): FT 6.1e-09; 28.6% identity in 346 aa overlap. Contains fam FT match to entry PF00165 HTH_AraC, Bacterial regulatory FT helix-turn-helix proteins, araC family and match to Prosite FT entry PS00041 Bacterial regulatory proteins, araC family FT signature. Contains also a TTA leucine codon, possible FT target for bldA regulation" FT /db_xref="GOA:Q9KY85" FT /db_xref="InterPro:IPR018062" FT /db_xref="UniProtKB/TrEMBL:Q9KY85" FT /protein_id="CAB92610.1" FT /translation="MPGDEQPRRGRRHTERGTAVEQTGTWDASVFLSTDSVSGPEGFGW FT WGDMVSRAVMPVSIASEHAGHFKGEVTTLELVDTDFSAFSFSPMSARRTPDHIRASDPE FT NYYLFLVHGSPIGLEQRRNNALLRAGDVALFDTSQPLACEFQDQGRPSRVSVLRLPRTA FT LPLPGDRTDRLVATPLPARTGSGALLTSYLAGLRENAAHCGPTELRRLGTMALELAVTF FT LAARLDSPPALPAESRRRVLLARINAYIDHNLHDPDLGPATIAAHHHISIRLLHALFEE FT EPETVGATIRRRRLERSRTDLGDPRLRHRTIGEIAARWGFRHPAAFSRTFREAYGISPT FT EARTALHDKQPCTPRRGPGHRTLAP" FT misc_feature 83222..83224 FT /gene="none" FT /note="TTA leucine codon. Possible target for bldA FT regulation" FT misc_feature 83297..83563 FT /note="Pfam match to entry PF00165 HTH_AraC, Bacterial FT regulatory helix-turn-helix proteins, araC family, score FT 70.90, E-value 2.7e-17" FT misc_feature 83405..83542 FT /note="PS00041 Bacterial regulatory proteins, araC family FT signature" FT CDS 83774..83983 FT /transl_table=11 FT /gene="SCO5018" FT /gene_synonym="SCK15.20" FT /product="putative integral membrane protein" FT /note="SCK15.20, possible integral membrane protein, len: FT 69 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9KY84" FT /protein_id="CAB92611.1" FT /translation="MHGDSSWHTTRSVPSIVVVVLIVIWTVFAVQWKEKDCALVPTSYL FT LVITHGTPSVFEGCGDHAIDVTDD" FT CDS complement(83993..84598) FT /transl_table=11 FT /gene="SCO5019" FT /gene_synonym="SCK15.21c" FT /product="putative secreted protein" FT /note="SCK15.21c, possible secreted protein, len: 201 aa; FT similar to TR:Q9UZM5 (EMBL:AJ248286;) Pyrococcus abyssi FT hypothetical 13.4 kD protein, 117 aa; fasta scores: opt: FT 167 z-score: 206.8 E(): 0.00048; 31.0% identity in 100 aa FT overlap. Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="InterPro:IPR003795" FT /db_xref="UniProtKB/TrEMBL:Q9KY83" FT /protein_id="CAB92612.1" FT /translation="MPISASATASFPLPGLSSLPHADSVKAAVAVSVSAVKRAGQRALT FT IGSWVGRGFSSAKQFCTEGIGMGRQRWRDGAGALVVVGQSGEGACVPLEIAGSYRARTK FT GLLGRGSVDGAMLLTPANSVHTFRMRMAIDVAYLDRRLNVIAVRTMRPGRLGLPRLRAR FT HVLEAEAGAMDEWGVRVGARVEVVEGSAESADGAGRLG" FT CDS 84591..85127 FT /transl_table=11 FT /gene="SCO5020" FT /gene_synonym="SCK15.22" FT /product="conserved hypothetical protein" FT /note="SCK15.22, hypothetical protein, len: 178 aa; similar FT to C-terminal region of TR:Q9KY81 (EMBL:AL356813) FT Streptomyces coelicolor putative lipoprotein SCK15.23, 221 FT aa; fasta scores: opt: 444 Z-score: 519.8 E(): 2.5e-21; FT 39.080% identity in 174 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9KY82" FT /protein_id="CAB92613.1" FT /translation="MGTTSPSASPTESESSKAGRPKIELPADLSYSFEWPKSGDQVKDA FT ILADAEQSIKAVDLAIVNQDALDKAYLYYYEGEAAAGTQKFIQNYVDQKAGITGRYRFY FT APEVAVDEDGTASFTYCEDQGRAYVKYLETNKVRRTEVSAQSYVIYHTSLKKNGEGVWE FT IQKIDSQSGSAKCRP" FT RBS 85305..85308 FT CDS 85315..85980 FT /transl_table=11 FT /gene="SCO5021" FT /gene_synonym="SCK15.23" FT /product="putative lipoprotein" FT /note="SCK15.23, possible lipoprotein, len: 221 aa; similar FT to Streptomyces coelicolor SCK15.24, 220 aa; fasta scores: FT opt: 736 z-score: 652.9 E(): 8.3e-31; 54.3% identity in 221 FT aa overlap. Contains correctly situated match to Prosite FT entry PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site and possible N-terminal region signal FT peptide sequence" FT /db_xref="UniProtKB/TrEMBL:Q9KY81" FT /protein_id="CAB92614.1" FT /translation="MNRRRPTLLAALTLTAAAALTLSACGSDGSPGKGEGEIAGSDVGD FT ESSASPSPSSSSTAAAGRPKVKLPPDLRLTFEDAETGDPVKDAVLADNAERMRAVDAAI FT SGTDPKGKALGFYNTGKALEAAVSWVGQFEKANATVTGHVRFFDRDVTLKGTTSAVLTF FT CADESKGFSKDKETGEVTKTPVTKDSYVQYNTRLDKNADGVWQTSQILSTRGAAQCQA" FT misc_feature 85357..85389 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS 86210..86214 FT CDS 86221..86883 FT /transl_table=11 FT /gene="SCO5022" FT /gene_synonym="SCK15.24" FT /product="putative lipoprotein" FT /note="SCK15.24, possible lipoprotein, len: 220 aa; similar FT to Streptomyces coelicolor SCK15.23, 221 aa; fasta scores: FT opt: 736 z-score: 703.5 E(): 1.3e-33; 54.3% identity in 221 FT aa overlap. Contains correctly situated match to Prosite FT entry PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site and possible N-terminal region signal FT peptide sequence" FT /db_xref="UniProtKB/TrEMBL:Q9KY80" FT /protein_id="CAB92615.1" FT /translation="MNRRRPTLLAALTLTAAAALTLSACGSDDDGAAKDSDKIAGADTG FT SETSAAPSPSETDTAGRPKITFPSDAKNVFEYEKTGNATKDAALADSTLSVNSVDEAIF FT EGSTDTKALGFYNAESALSDSITYVLGYINKNHTWVGETRYFDYKVSLSGELEAYVTYC FT SDESKSFIKDKKTGKVKDTPTTADSYVLYHAKLAKNAQGVWQTTDIASTRGSKECQP" FT misc_feature 86263..86295 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS 86892..87902 FT /transl_table=11 FT /gene="SCO5023" FT /gene_synonym="SCK15.25" FT /product="putative secreted protein" FT /note="SCK15.25, possible secreted protein, len: 336 aa; FT similar to TR:CAB77312 (EMBL:AL160312) Streptomyces FT coelicolor putative secreted protein SCD35.28c, 361 aa; FT fasta scores: opt: 890 z-score: 972.2 E(): 0; 47.3% FT identity in 357 aa overlap. Contains possible N-terminal FT region signal peptide sequence" FT /db_xref="UniProtKB/TrEMBL:Q9KY79" FT /protein_id="CAB92616.1" FT /translation="MRCATVAAIVLVSVISAPMAFAGGRGEGGSRGSTDQQANADGNGT FT VSVTVGGVVFDRSKNGSGDSVGAVTSSTSWSPPACWYAPKYTPEELQDYLEPIWEAEST FT GYEWDAKQREKYNAKDEKKGFNKDKTGKGFWWGSYVNESFPPGWDKCDTDYFWVDTGDP FT PPADKENAVTPEVLAELAYAEIRVPGTEVTLAPAEATKVNLPTWAWLDGAEFKPVSVTA FT SVKEIGIEATATAEPVSLQIKPGTPDAETYPASGVCEIKNGRIGAPYEKGRADDAPPCG FT VKYLRSSGDGTFPLQATVTWEIHWTGTGGAGGDLPDGTFGATQDVVVQEIQAVNR" FT CDS 88019..88891 FT /transl_table=11 FT /gene="SCO5024" FT /gene_synonym="SCK15.26" FT /product="putative oxidoreductase" FT /note="SCK15.26, possible oxidoreductase, len: 290 aa; FT similar to TR:Q9UXP0 (EMBL:AJ011519) Methanolobus tindarius FT F420-dependent N5,N10-methylene-tetrahydromethanopterin FT reductase, putative FfdA, 326 aa; fasta scores: opt: 323 FT z-score: 369.8 E(): 4e-13; 28.3% identity in 240 aa FT overlap" FT /db_xref="GOA:Q9KY78" FT /db_xref="InterPro:IPR016048" FT /db_xref="UniProtKB/TrEMBL:Q9KY78" FT /protein_id="CAB92617.1" FT /translation="MTGLGAVFRPQLAPERLRAVARVADEVGLEELWLWEDCFREGGIS FT TAAAALAWTERVRVGVGLLPVPLRNVAVTAMEAATLHRMFPGRPVLGVGHGVQDWMGQV FT GARAESPLTLLREHLVALRELLRGGRVTSTGRYVRLDDVALDWPPEQPVEVLAGATGPR FT SLRLAGEAADGTVLTANTPPDGVRRARRLIDEGRAASGRTEAHRVVVYLLAATGSGAAE FT RLRNELVAEGVGAVPDLGVAGDAQAVADAVRRLAEAGADTVILQPTGDEPDPEGFVRFA FT AERVRPLVA" FT CDS 88994..89911 FT /transl_table=11 FT /gene="SCO5025" FT /gene_synonym="SCK15.27" FT /product="putative transcriptional regulator" FT /note="SCK15.27, possible transcriptional regulator, len: FT 305 aa; similar to TR:Q9RJS9 (EMBL:AL132707) Streptomyces FT coelicolor putative transcriptional regulator SCF51.06 334 FT aa; fasta scores: opt: 166 z-score: 190.7 E(): 0.0037; FT 27.3% identity in 289 aa overlap and to SW:TIPA_STRLI FT (EMBL:S64314) Streptomyces lividans transcriptional FT activator TipA, 253 aa; fasta scores: opt: 174 z-score: FT 201.3 E(): 0.00096; 35.5% identity in 107 aa overlap. FT Contains Pfam match to entry PF00376 merR, Bacterial FT regulatory proteins, merR family and possible FT helix-turn-helix at residues 11..32 (+2.74 SD)" FT /db_xref="GOA:Q9KY77" FT /db_xref="InterPro:IPR000551" FT /db_xref="UniProtKB/TrEMBL:Q9KY77" FT /protein_id="CAB92618.1" FT /translation="MRSSFMPPRQVKIGDAAAFVGSTPRAIRHYHEIGLLPEPERGSDG FT RRRYGYEDMIRLLWIRRTADAGIALDDIRDAFATGTDSAGAESGEDVAGILERLEETLA FT EREAELRRQRAAVRRMRTEGSRTGLLSDFVTERLKSAPEGSLRQADLDSLLVTERILGP FT LGAAVQATRFVVLATHPALREESDRVDDAEEALDDGVAVDDPRVAQVAAERRAFESALE FT AVIEESGPGADDDALFDAWDTLHPAADGAGEADSVSAFEATGWMPYDFSPARLRCMELA FT AELAADPSARDNTAAQSYRAEPSS" FT misc_feature 89033..89140 FT /note="Pfam match to entry PF00376 merR, Bacterial FT regulatory proteins, merR family, score 39.80, E-value FT 6e-08" FT RBS 89896..89899 FT CDS 89908..90726 FT /transl_table=11 FT /gene="SCO5026" FT /gene_synonym="SCK15.28" FT /product="conserved hypothetical protein SCK15.28" FT /note="SCK15.28, hypothetical protein, len: 272 aa; similar FT to TR:O06593 (EMBL:Z95586) Mycobacterium tuberculosis FT hypothetical 27.9 kD protein MTCY336.07c, 252 aa; fasta FT scores: opt: 968 z-score: 1156.3 E(): 0; 57.5% identity in FT 254 aa overlap" FT /db_xref="GOA:Q9KY76" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:Q9KY76" FT /protein_id="CAB92619.1" FT /translation="MTPPAHPGTFERLVAEGAAVPTEGWDFSWFEGRATEARPSWGYAR FT SMAGRLAGATAVLDVQTGGGEVLDFALEAAGPHRAPLVAATEGWAPNVAQATRLLRPRG FT VPVVASADDAPLPFADGAFDLVVSRHPVEPHWDEVARVLMPGGTYFAQHVGPASVFELI FT EYFLGPLPEDSRRHRDPERERADAEAAGLEVVELRAERLRMEFLDIGAVVHFLRKVVWM FT VPGFTVEAYRDRLRDLHERIEADGPFVAHSSRHLFDVRKPDATSGPDARP" FT CDS complement(90757..91950) FT /transl_table=11 FT /gene="SCO5027" FT /gene_synonym="SCK15.29c" FT /product="hypothetical protein SCK15.29c" FT /note="SCK15.29c, hypothetical protein, len: 397 aa; FT similar to TR:Q9RKN1 (EMBL:AL121850) Streptomyces FT coelicolor hypothetical 37.4 kD protein (fragment) FT SCC78.05, 347 aa; fasta scores: opt: 180 z-score: 199.8 FT E(): 0.0012; 28.6% identity in 360 aa overlap" FT /db_xref="InterPro:IPR009351" FT /db_xref="UniProtKB/TrEMBL:Q9KY75" FT /protein_id="CAB92620.1" FT /translation="MTKSTGITWAAASARRLERQFLARRARTGTPVADVAAAMLGVHAQ FT VLSAAELSVGLRADGVTRTDVRDALWPTAPLAPPAPALVKTHGPRGTVHLLPARDLPMW FT CAALPAIPAGPAAFPTDVRLTGEQAGQVVAAIADALDGTFLTVDELGEEVVARTGPWAG FT DLVMPAFQTMWPRWRQVLHRAGQCGALSFGPNRGRRVTYTRPPRFTPLPPEEASRLLAR FT RYLYAYGPATPQHFARWLAAPPGWAKARYAELAAAGEIEEVRFEGAPAWVAAGDTAFPD FT APERDELLRGVRLLPYFDAYVVAAQPRELLFPGAAYRRALAGGQAGNFPVLLVDGVAAG FT VWHQRRRGRRTTVTVEPLARLTARQERELADCVERVGAVLEAAAELVIGEVTVGAHA" FT misc_feature 92236..92434 FT /note="high G+C content region (81.4%)" FT CDS 93012..94337 FT /transl_table=11 FT /gene="SCO5028" FT /gene_synonym="SCK7.01" FT /product="putative ATP-binding protein" FT /note="SCK7.01, possible ATP-binding protein, len: 441 aa; FT similar to TR:Q9X792 (EMBL:AL049491) Mycobacterium leprae FT putative ATP-binding protein MLCB1222.20, 433 aa; fasta FT scores: opt: 2024 z-score: 2236.8 E(): 0; 72.2% identity in FT 428 aa overlap. Contains and match to Prosite entry PS00017 FT ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9FBP8" FT /db_xref="InterPro:IPR006596" FT /db_xref="UniProtKB/TrEMBL:Q9FBP8" FT /protein_id="CAC05873.1" FT /translation="MVTSTKRHKPDRRTYVLDTSVLLADPNALNRFDEHEVVLPIVVVT FT ELEAKRHHPELGYFARQALRLLDEFRVRHGRLDAPIPIGDLGGTVRVELNHSDPSVLPT FT GYRLGDNDSRILAVARNLQAEGFDVTVVSKDLPLRIKASSVGLLAEEYRAELAITDASG FT WTGMSELTLPGEQVDVLFEEGRVYVPEAAGLPVHTGLTIQSERGKALGRVTPDGNVRLV FT RGDREAFGIKGRSAEQRIALDLLLDPDVGIVSMGGRAGTGKSALALCAGLEAVLERRQH FT QKVMVFRPLYAVGGQELGYLPGSEAEKMSPWAQAVFDTLSAVTSREVIEEVTARGMLEV FT LPLTHIRGRSLHDAFVIVDEAQSLERNVLLTVLSRIGANSRVVLTHDVAQRDNLRVGRY FT DGVVAVVEKLKGHPLFAHVTLTRSERSQIAALVTEMLEDGHI" FT misc_feature 93780..93803 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 94767..95483 FT /transl_table=11 FT /gene="SCO5029" FT /gene_synonym="SCK7.02" FT /product="putative secreted protein" FT /note="SCK7.02, possible secreted protein, len: 238 aa; FT similar to C-terminal region of TR:CAB93446 (EMBL:AL357591) FT Streptomyces coelicolor hypothetical 16.0 kDa protein FT SCC53.17, 154 aa; fasta scores: opt: 477 z-score: 484.5 FT E(): 1.6e-19; 64.4% identity in 101 aa overlap. Contains FT possible N-terminal region signal peptide sequence and FT possible coiled-coil region at aprox. residues 82..123" FT /db_xref="GOA:Q9FBP7" FT /db_xref="InterPro:IPR010618" FT /db_xref="UniProtKB/TrEMBL:Q9FBP7" FT /protein_id="CAC05874.1" FT /translation="MLEGNRVSRISVRGFAVASATAVTAVGSVVGVASGSVAQNNDDAE FT ATAAGTTLLADIPMGEQAQVQTASLTQQADVQAIAADASAKKDAEEAARKAAAKTAVDK FT QEKAKKAAQAAKQREAQQEAASRDAKRESTSFAVQSSYSTSQIQAMARQMVPSGQFQCF FT SNIVNHESSWNYQAVNASSGAYGLFQALPAGKYASAGADWRTNPATQIKWGLSYMDNRY FT GSPCDAWAFWQANHWY" FT RBS 95635..95638 FT CDS 95646..97043 FT /transl_table=11 FT /gene="SCO5030" FT /gene_synonym="SCK7.03" FT /product="putative integral membrane protein" FT /note="SCK7.03, possible integral membrane protein, len: FT 465 aa; similar to SW:Y205_MYCTU (EMBL:AL021928) FT Mycobacterium tuberculosis hypothetical 38.0 kDa protein FT MTV033.13, 367 aa; fasta scores: opt: 892 z-score: 833.4 FT E(): 0; 41.1% identity in 343 aa overlap. Contains Pfam FT match to entry PF01594 UPF0118, Domain of unknown function FT DUF20 and possible hydrophobic membrane spanning regions" FT /db_xref="InterPro:IPR002549" FT /db_xref="UniProtKB/TrEMBL:Q9FBP6" FT /protein_id="CAC05875.1" FT /translation="MSRVPGWLGRLGAGLTRASERLEQRREEARRDDADDGPGPVSDHE FT RRPLDDTAEDSAVEHLAAHRPVALAHRPDPAQAVPWGVRVAAEAGWRLLVLAGTVWVLM FT RVISAVQLVVLAFVAALLITALLQPAVAWLRRHGVPRGPATALTAILGFVVMGLIGWFV FT TWQVMENIDNLSDQVQDGIDELRNWLLNSPFHVTDKQINEIAKNLRDAVGANTDQITSA FT GLEGVTVVVEALTGILLAAFSTLFLLYDGKRIWQWSLKLVPAAARPGVAGAGPRAWRTL FT TAYVRGTVIVALIDAIFIGLGIYFLDVPMAVPLAVFIFLFAFIPLVGAVVSGALAVVVA FT LVTQGVFAAVMTLVVVLAVQQIEGHILQPFILGRAVRVHPLAVVLSVAAGGMVAGIGGA FT VVAVPLVAVTNTVVGYLRAYSREAALRRTPRPHGATSTDAAPAVDRVPGPPKPPAPPAD FT GPPSDAP" FT misc_feature 95913..96896 FT /note="Pfam match to entry PF01594 UPF0118, Domain of FT unknown function DUF20, score 201.10, E-value 1.7e-56" FT misc_feature 97128..99737 FT /note="previously sequenced fragment. EMBL:AF186371 FT Streptomyces coelicolor A3(2) AhpD (ahpD), AhpC (ahpC), and FT OxyR (oxyR) genes, complete cds." FT CDS complement(97332..97868) FT /transl_table=11 FT /gene="SCO5031" FT /gene_synonym="ahpD" FT /gene_synonym="SCK7.04c" FT /product="alkyl hydroperoxide reductase system hypothetical FT protein" FT /note="SCK7.04c, ahpD, alkyl hydroperoxide reductase system FT hypothetical protein, len: 178 aa; identical to previously FT sequenced TR:Q9RN73 (EMBL:AF186371) Streptomyces coelicolor FT A3(2) AhpD, 178 aa" FT /db_xref="GOA:Q7AKI6" FT /db_xref="InterPro:IPR003779" FT /db_xref="UniProtKB/Swiss-Prot:Q7AKI6" FT /protein_id="CAC05876.1" FT /translation="MSLDSLKSAVPDYAKDLKLNLGSVIGNSDLPAQQLWGTVLATAIA FT SRSPIVLRELEPEAKANLSPEAYSAAKSAAAVMAMNNVFYRTRHLLSDHEYGTLRAGLR FT MNVIGNPGVDKVDFELWSFAVSAINGCGMCLDSHEQVLRKAGVDRETIQEAFKIAAVVE FT AVGVTLDAEAVLAAE" FT CDS complement(97875..98429) FT /transl_table=11 FT /gene="SCO5032" FT /gene_synonym="ahpC" FT /gene_synonym="SCK7.05c" FT /product="alkyl hydroperoxide reductase" FT /note="SCK7.05c, ahpC, alkyl hydroperoxide reductase, FT len:184 aa; identical to previously seqeunced TR:Q9RN72 FT (EMBL:AF186371) Streptomyces coelicolor A3(2) AhpC, 184 aa. FT Contains Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA FT family" FT /db_xref="GOA:Q9FBP5" FT /db_xref="HSSP:1QMV" FT /db_xref="InterPro:IPR012335" FT /db_xref="UniProtKB/TrEMBL:Q9FBP5" FT /protein_id="CAC05877.1" FT /translation="MLTVGDKFPEFDLTACVSLEKGKEFQQINHKTYEGQWKVVFAWPK FT DFTFVCPTEIAAFGKLNDEFADRDAQILGFSGDSEFVHHAWRKDHPDLTDLPFPMLADS FT KHELMRDLGIEGEDGFAQRAVFIVDQNNEIQFTMVTAGSVGRNPKEVLRVLDALQTDEL FT CPCNWSKGDETLDPVALLSGE" FT misc_feature complement(97971..98420) FT /note="Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA FT family, score 159.60, E-value 5.2e-44" FT RBS complement(98435..98438) FT RBS 98553..98558 FT CDS 98567..99505 FT /transl_table=11 FT /gene="SCO5033" FT /gene_synonym="oxyR" FT /gene_synonym="SCK7.06" FT /product="hydrogen peroxide sensing regulator" FT /note="SCK7.06, oxyR, hydrogen peroxide sensing regulator, FT len: 312 aa; identical to previously sequenced TR:Q9RN71 FT (EMBL:AF186371) Streptomyces coelicolor A3(2) hydrogen FT peroxide sensing regulator OxyR, 313 aa. Contains Pfam FT match to entry PF00126 HTH_1, Bacterial regulatory FT helix-turn-helix protein, lysR family and match to Prosite FT entry S00044 Bacterial regulatory proteins, lysR family FT signature. Also contains possible helix-turn-helix motif at FT residues 23..44 (+3.89 SD)" FT /db_xref="GOA:Q9FBP4" FT /db_xref="HSSP:1IXC" FT /db_xref="InterPro:IPR005119" FT /db_xref="UniProtKB/TrEMBL:Q9FBP4" FT /protein_id="CAC05878.1" FT /translation="MSSKKRQPSLAQLRAFDAVAEHLHFRDAAAAIGMSQPALSGAVSA FT LEEALGVTLLERTTRKVLLSPAGARLAVRTKAVLAEVGALVEEAEAVRAPFTGALRLGV FT IPTVAPYLLPTVLRLVHERYPDLDLQVHEEQTASLLEGLTTGRLDLLLLAVPLGVPGVT FT ELPLFDEDFVLVTPLDHRLGGREGLERSVLRELKLLLLDEGHCLRDQALDICREAGRAG FT VPATTTAAGLSTLVQLVAGGLGVTLLPRTAVRVETSRSSQLLTASFTDPAPTRRIALAM FT RTGAARSAEYGELAAALREAMADLPVRTVHD" FT misc_feature 98594..99022 FT /note="Pfam match to entry PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix protein, lysR family, score FT 165.90, E-value 6.6e-46" FT misc_feature 98636..98728 FT /note="PS00044 Bacterial regulatory proteins, lysR family FT signature" FT CDS complement(99633..101969) FT /transl_table=11 FT /gene="SCO5034" FT /gene_synonym="SCK7.07c" FT /product="putative integral membrane protein" FT /note="SCK7.07c, possible integral membrane protein, len: FT 778 aa; similar to TR:AAF74504 (EMBL:M34538) Streptomyces FT clavuligerus hypothetical 42.6 kDa protein (fragment) 407 FT aa; fasta scores: opt: 509 z-score: 559.6 E(): 1.1e-23; FT 31.5% identity in 413 aa overlap. Contains possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9FBP3" FT /db_xref="InterPro:IPR003838" FT /db_xref="UniProtKB/TrEMBL:Q9FBP3" FT /protein_id="CAC05879.1" FT /translation="MRQWAADLMLGVRFAFTGGREGWTRAVLTAVGVGLGVALLLLTTA FT LPNALTVRHDREAARSDITFATDPMPKADDTLVLARLDDTFRDDDVRGRALEPEGPRAP FT LPPGLEKFPAVGEMVVSPALKKLLNSDSGALLRERLPDRVVGTIAEEGLIGSAELAYYR FT GAEGLAEHITSGRIERIDRFGDPDPGEERSDPVLILLILVVFVVLLMPVAVFIAAAVRF FT GGERRDRRLAALRLVGSDSRMTRRIAAGEAMAGAALGLLFGAGFFMVGRQLAGSAEVFR FT ISVFPSYLNPSPVLALLVAVAVPTAAVLVTLLALRGVVIEPLGVVRAGRPARRQLWWRL FT ILPLAGLAMLYPMIGNGRENGDFNQYLVTGGVVLLLVGVTALLPWVVESVVARLGSGGV FT AWQLAVRRLQLSSGTAARMVNGIAVAVAGAIALQMLFAGVDDDYTKSTGQDVSWAQMEA FT ILPSGVPMDQAAAKFRDTKGVEAVNAFSEGWLGDRPKDPDHGTTLTVGDCASLREIARL FT SSCAEGDVFVVHGAEWDAEEDVTKLAAPGRKLYVDPSYEGIPKRHEIPWTVPQGVKAAK FT PRTGLLAGTDRGGLLITRKAMPEALAPALDGHAYLRLDQSVPDVHDLVRNTTVAIDPLA FT DAVAWAATERTDRFDAIRTGLFVGAACVLALIGASLLVSQLEQLRERKKLLSALVAFGT FT RRRTLSLSVLWQTAIPIVLGLLLASVVGLTLGTVLLKMTSTPVSVDWTGVLAMTGIGAA FT VVLVVTLCSLPPLLRLMRPEGLRTE" FT CDS complement(101972..102661) FT /transl_table=11 FT /gene="SCO5035" FT /gene_synonym="SCK7.08c" FT /product="putative ABC transporter ATP-binding protein" FT /note="SCK7.08c, possible ABC transporter ATP-binding FT protein, len: 229 aa; similar to TR:CAB81857 FT (EMBL:AL161691) Streptomyces coelicolor putative ABC FT transporter ATP-binding protein SCD40A.12c, 246 aa; fasta FT scores: opt: 597 z-score: 668.0 E(): 9.7e-30; 47.6% FT identity in 206 aa overlap. Contains Pfam match to entry FT PF00005 ABC_tran, ABC transporter and match to Prosite FT entry PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9FBP2" FT /db_xref="HSSP:1L2T" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9FBP2" FT /protein_id="CAC05880.1" FT /translation="MTPPAGSLLSADQLRKAYGPTLALDGAEFSIHPGEVVAVMGPSGS FT GKSTLLHCLAGIVPPDSGTITYNGRELSAMSDAQRSALRRSDFGFVFQFGQLVPELTCV FT ENVALPLRLNGTSRKEAERAALSWMERLEVDDLRKKRPGEVSGGQGQRVAVARSLVTNP FT RVLFADEPTGALDSLNGERVMELLTDAARSTNAAVVLVTHEARVAAYSDREIVVRDGKS FT RDMERAV" FT misc_feature complement(102002..102562) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 224.40, E-value 1.6e-63" FT misc_feature complement(102518..102541) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(102658..103182) FT /transl_table=11 FT /gene="SCO5036" FT /gene_synonym="SCK7.09c" FT /product="hypothetical protein" FT /note="SCK7.09c, hypothetical protein, len: 174 aa; similar FT to TR:O50432 (EMBL:AL010186) Mycobacterium tuberculosis FT hypothetical 21.1 kDa protein MTV005.12c, 189 aa; fasta FT scores: opt: 183 z-score: 238.8 E(): 7.8e-06; 30.1% FT identity in 186 aa overlap" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9FBP1" FT /protein_id="CAC05881.1" FT /translation="MSIGHTLLGLLESGPRHGYDLKRAFDEKFGHDRPLHYGQVYSTMS FT RLLKNGLVVVDGIEAGGGPERKRYAITDEGITDVQRWLATPEKPEPYLQSTLYTKVVLA FT LLTHRDAADILDTQRSEHLRSMRILTDRKRKGDLADQLICDHALFHLEADLRWLELTAA FT RLDKLREAVTR" FT CDS complement(103366..103671) FT /transl_table=11 FT /gene="SCO5037" FT /gene_synonym="SCK7.10c" FT /product="hypothetical protein SCK7.10c" FT /note="SCK7.10c, unknown, len: 101 aa. Highly hydrophilic. FT Also high in G+C content (80.52 %)" FT /db_xref="UniProtKB/TrEMBL:Q9FBP0" FT /protein_id="CAC05882.1" FT /translation="MTSPPEDSAPEDSVRDSAPSEGPAPKRRPHQRKQVLLRLDPQVYE FT ALARWAGDELRSANAQIEFLLRRALAEAGRLPGGTGPLPRRGRPPGGGGPGAAPPP" FT CDS complement(103668..104606) FT /transl_table=11 FT /gene="SCO5038" FT /gene_synonym="SCK7.11c" FT /product="putative integral membrane protein" FT /note="SCK7.11c, possible integral membrane protein, len: FT 312 aa; similar to TR:Q9RDB7 (EMBL:AL136058) Streptomyces FT coelicolor putative membrane protein SCE20.08c, 383 aa; FT fasta scores: opt: 467 z-score: 517.9 E(): 2.2e-21; 31.2% FT identity in 301 aa overlap. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="InterPro:IPR001107" FT /db_xref="UniProtKB/TrEMBL:Q7AKI5" FT /protein_id="CAC05883.1" FT /translation="MSTHDAPQVTADVPEMPAPRVRENQAHSIGGGFALLLGLVGLLVG FT AGLIAGATAVDSTGGKAVLIIGGILIALAAFLAMCGLNMVAPGEARVVQLFGRYRGTIR FT QDGLRWVNPFTSRTKISTRVRNHETAVLKVNDAYGNPIELAAVVVWRVEDTAQATFEVD FT DYVEFVSTQTEAAVRHIAIEYPYDAHDEDGLSLRGNAEEITEKLAVELHARVEAAGVQI FT IESRFTHLAYAPEIASAMLQRQQAGAVVAARRQIVDGAVGMVEAALARISEQDIVELDD FT ERKAAMVSNLMVVLCGDRAAQPVLNTGTLYQ" FT CDS 105026..107176 FT /transl_table=11 FT /gene="SCO5039" FT /gene_synonym="SCK7.12" FT /product="putative penicillin-binding protein" FT /note="SCK7.12, possible penicillin-binding protein, len: FT 773 aa; similar to TR:CAB88838 (EMBL:AL353832) Streptomyces FT coelicolor probable penicillin-binding protein SCE6.34, 756 FT aa; fasta scores: opt: 1080 z-score: 911.6 E(): 0; 46.0% FT identity in 733 aa overlap and to SW:PBPD_BACSU FT (EMBL:U11882) Bacillus subtilis penicillin-binding protein FT 4 precursor PbpD, 624 aa; fasta scores: opt: 513 z-score: FT 438.2 E(): 6.1e-17; 28.7% identity in 582 aa overlap. FT Contains Pfam matches to entries PF00912 Transglycosyl, FT Transglycosylase and PF00905 Transpeptidase, Penicillin FT binding protein transpeptidase domain and 2x matches to FT Prosite entry PS00017 ATP/GTP-binding site motif A FT (P-loop)" FT /db_xref="GOA:Q9FBN9" FT /db_xref="InterPro:IPR001460" FT /db_xref="UniProtKB/TrEMBL:Q9FBN9" FT /protein_id="CAC05884.1" FT /translation="MGAFIVLYMMIDIPEGNPEADLQSNVYKYSDGSIMARTGERNREI FT VDLAKIPKDVQRTFVAAENKTFYNDAGVDLKGTARGVLNTLSGKGAQGGSTITQQYVKN FT YYLTQEQTVSRKLKELVISLKLDREKSKDYILAGYINTSYYGRGAYGIQAAAQAYYRVD FT AEDLTVEQGAYLSALLQAPNQYDWAIASETGKKLVQQRWNYVLDNMVEQKWLGAGDRQG FT MKFPEPKEPKAAAGKEGQVGYLVDAADHALKKQLVAQGAAEDMEQAKALVDLGGYTVTL FT NIDKKKQAALEAAVKKQLTSKLDPDERKVDADVQAGAASVDPKTGSVVAMYGGVNYLKH FT FTNNATRDDYQPASTFKPVILAAAVDHDAETQDGVPITANTLYDGDSERPVMDGDKKVG FT FAPPNEDDHDYGEIDVQEAMNKSVNSVFAQMGIDVGMPEVMKVAADLGMDTEGEQAVPA FT QTLGSMGASPLEMAGVYATFDNHGKKVTPAIVKSVEHKDRKVEMPDPIGEQVISREAAD FT TVTSVLTGVVNDGTAKKSVRENPLRDGQKVAGKTGTSDNNKSAWFSGFTPGLVTSVGLF FT GEDDEPPHKQVPMYKAAGVDYRVNGGGPPAEIWAAYTFGVMDEVTEFDLETKQGAAVRP FT SKSPTAPESPTKSPTREETSEAPPPSSDPTTEAPPSSDPTTEEPPESPTNSPSNSPSTE FT PPPDGGSTESGDPELPGVDWGQ" FT misc_feature 105095..105598 FT /note="Pfam match to entry PF00912 Transglycosyl, FT Transglycosylase, score 190.50, E-value 2.6e-53" FT misc_feature 105866..106801 FT /note="Pfam match to entry PF00905 Transpeptidase, FT Penicillin binding protein transpeptidase domain, score FT 74.70, E-value 1.9e-18" FT misc_feature 106655..106678 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(107315..109528) FT /transl_table=11 FT /gene="SCO5040" FT /gene_synonym="SCK7.13c" FT /product="conserved hypothetical protein" FT /note="SCK7.13c, conserved hypothetical protein, len: 737 FT aa; similar to TR:Q9ZBJ0 (EMBL:AL035161) Streptomyces FT coelicolor conserved hypothetical protein SC9C7.20, 860 aa; FT fasta scores: opt: 1430 z-score: 1211.3 E(): 0; 37.5% FT identity in 787 aa overlap. Contains match to Prosite FT entry, TTA leucine codon, possible target for bldA FT regulation and 3x degenerate repeat (P/A)(D/G)GGQ" FT /db_xref="GOA:Q9FBN8" FT /db_xref="InterPro:IPR010822" FT /db_xref="UniProtKB/TrEMBL:Q9FBN8" FT /protein_id="CAC05885.1" FT /translation="MTEHPTSFDRPSTGADPTDPRGALLPAPVPPRASGSALPAQGRTG FT ETPPTAGEDSPGVFEHSQPGAEQAAEPDTHRPRPGAEGVPVQPDGGQPDGGQAGGGQPG FT GVPAGAAPRVAPSDGSALDGMPGGGQAAEVRPGSEVPAGATDRRDAPAEPDRRTGQPTA FT PGQPTPMRRDGDRLRFVGAATRRIARGMDLDEIVMGLCRATVPTFADAILVYLREPLPV FT GDERPTGPLVLRLRRTDRIPAERDTEGGFAPAAQPEPSELETVGAELCEVRPGSALAEV FT LRGVRPVFTDTPAARAALPELLGEERDFALPDGRRAILAPLRGRRRVIGAALFLRGPER FT IPFEADDLLVAAQLATHSALGIDKAVLYGREAYIADELQRTMLPENLPRCTGVRLASRY FT LPAAETARVGGDWYDAIPLPGSRVALVVGDVMGHSMTSAAIMGQLRTTAQTLAGLDLPP FT QEVLHHLDEQAQRLGTDRMATCLYAVYDPVSHRITVANAGHPPPVLLHLGGEAEVLRVP FT AGAPIGVGGVDFEAVELDAPAGATLLLYTDGLVESRLRDVWTGIEQLRERLAATAQLTG FT PDHPPPLEALCDEVLDMLGPGDRDDDIALLAARFDGIAPSDVSYWFLDPEDAAPGKARR FT LARRALARWGMEDLTDAVELLVSEVVTNAVRYASKPVTLRLLRTDVLRCEVGDDVPQLP FT RLRQARATDEGGRGLYLVNRLARRWGATRLSTGKVVWFELNRG" FT repeat_region complement(109223..109267) FT /note="3x degenerate repeat translated into SCK7.13c" FT misc_feature complement(109415..109417) FT /gene="none" FT /note="TTA leucine codon. Possible target for bldA FT regulation" FT CDS complement(109825..110535) FT /transl_table=11 FT /gene="SCO5041" FT /gene_synonym="SCK7.14c" FT /product="hypothetical protein" FT /note="SCK7.14, hypothetical protein, len: 236 aa; similar FT to TR:O83033 (EMBL:AB016934) Streptomyces wedmorensis FomD FT protein, 209 aa; fasta scores: opt: 282 z-score: 320.1 E(): FT 2.3e-10; 34.5% identity in 197 aa overlap" FT /db_xref="InterPro:IPR007295" FT /db_xref="PDB:3CBT" FT /db_xref="UniProtKB/TrEMBL:Q9FBN7" FT /protein_id="CAC05886.1" FT /translation="MTDGEAVSAAAGPGAEGPPGPVGHWAPGSHILWRYRENGGPHVHI FT ARPVTVVRDDADLLAVWLAPGTECVKPVLADGTPVHLEPLATRYTKPRTVQRDQWFGTG FT VLKLARPGEAWSVWLFWDPGWRFKNWYVNLERPLTRWEGGVDSEDHFLDISVHPDRTWH FT WRDEDEFAQALRDGLMDPASAGRVRRAGRSAVAEIRAWGSPFADGWEHWRPDPAWPVPS FT LPGDWDRTPAHVSS" FT CDS complement(110624..112009) FT /transl_table=11 FT /gene="SCO5042" FT /gene_synonym="fumC" FT /gene_synonym="SCK7.15c" FT /product="fumarate hydratase C" FT /note="SCK7.15c, fumC, fumarate hydratase C, len: 461 aa; FT similar to SW:FUMC_PSEAE (EMBL:U59458) Pseudomonas FT aeruginosa fumarate hydratase C (EC 4.2.1.2) FumC, 458 aa; FT fasta scores: opt: 1505 z-score: 1638.8 E(): 0; 53.6% FT identity in 459 aa overlap. Contains Pfam match to entry FT PF00206 lyase_1, Lyase and match to Prosite entry PS00163 FT Fumarate lyases signature" FT /db_xref="GOA:Q9FBN6" FT /db_xref="HSSP:1FUQ" FT /db_xref="InterPro:IPR000362" FT /db_xref="UniProtKB/Swiss-Prot:Q9FBN6" FT /protein_id="CAC05887.1" FT /translation="MSEYRIEHDSMGEVRVPADAKWRAQTQRAVENFPVSGQRIERAHI FT EALARIKSAAAKVNAELGVLDEDVAGAIQEAAGEVAEGKWDEHFPVDVFQTGSGTSSNM FT NTNEVVATLATERLGRDVHPNDHVNASQSSNDVFPSSIHIAATAAVTRDLIPALDHLAG FT ALERKAGEFADVVKSGRTHLMDATPVTLGQEFGGYAAQVRYGIERLQASLPRLAELPLG FT GTAVGTGINTPPGFSAAVIEEVARATGLPLTEARDHFEAQGARDGIVETSGQLRTIGVG FT LTKIANDLRWMASGPRTGLAEISLPDLQPGSSIMPGKVNPVIPEAVLMVAAQVTGNDAT FT VAAAGAAGNFELNVMLPVIAKNVLESVRLLANVSRLLADRTVDGIVAHPERAREYAESS FT PSVVTPLNKYLGYEEAAKVAKRALAERKTIRQTVLEGGYVERGDLTREQLDQALDVLRM FT TRP" FT misc_feature complement(110642..111976) FT /note="Pfam match to entry PF00206 lyase_1, Lyase, score FT 508.30, E-value 5.9e-149" FT misc_feature complement(111050..111079) FT /note="PS00163 Fumarate lyases signature" FT CDS complement(112101..113561) FT /transl_table=11 FT /gene="SCO5043" FT /gene_synonym="SCK7.16c" FT /product="putative hydrolase (putative membrane protein)" FT /note="SCK7.16c, probable hydrolase (putative membrane FT protein), len: 486 aa; N-terminal similar to SW:APX_STRGR FT Streptomyces griseus aminopeptidase (EC 3.4.11.-), 284 aa; FT fasta scores: opt: 967 z-score: 1057.3 E(): 0; 53.7% FT identity in 283 aa overlap and C-terminal region similar to FT TR:O69311 (EMBL:D84193) Streptomyces lividans chitinase (EC FT 3.2.1.14) ChiB, 610 aa; blastp scores: Score = 87 (30.6 FT bits), Expect = 2.1, P = 0.87; Identities = 46/159 (28%), FT Positives = 60/159 (37%). Contains possible hydrophobic FT membrane spanning region" FT /db_xref="GOA:Q9FBN5" FT /db_xref="HSSP:1QQ9" FT /db_xref="InterPro:IPR007484" FT /db_xref="UniProtKB/TrEMBL:Q9FBN5" FT /protein_id="CAC05888.1" FT /translation="MRTCPAWPPLSHFWRTKVKRRFAVASLSLAVVLGLGTLPAVAAGT FT APAAQSPDVDVTKVKAHLTELHSIAGRNGGTRRSTGQGYRDSVAYVKGKLQAAGYTVTE FT QPCTSGCSSGAGPNLIAEWPHGDANDVYMFGAHLDSVSAGPGMNDNGSGSAALLENALT FT LARQNPTMQGRVRFAWWTDEEQGLNGSDFYVRSLSSAQRSAITAYYNFDMIASTNGGYF FT VNHVTSAAAAPMKAYWDSLGLQPEENTEGAGRSDDYSFEQYGIPTSGYAMGASARKTSA FT QAAKWGGTAGTSYDPCYHRSCDNLDNINTTGLDRASDGIAYTIWQRAVGTGDDGGGDGC FT DTDPVVNGGFESGSSPWTGDTGTIGAHSGQSAHTGTRFAWLAGYGSTHTESVAQTVTVP FT TGCTRLAYWLHIDTDESGTTAYDTFKVKADGTTLATLSNADARDGYVQRTVDLGAYAGR FT QVALSFTGSEDGSLQTGFVLDDVSLLAG" FT CDS complement(113742..115418) FT /transl_table=11 FT /gene="SCO5044" FT /gene_synonym="fumB" FT /gene_synonym="SCK7.17c" FT /product="fumarate hydratase class I" FT /note="SCK7.17c, fumB, fumarate hydratase class I, len: 558 FT aa; similar to SW:FUMB_ECOLI (EMBL:M27058) Escherichia coli FT fumarate hydratase class I, anaerobic (EC 4.2.1.2) FumB, FT 548 aa; fasta scores: opt: 2386 z-score: 2782.7 E(): 0; FT 64.9% identity in 539 aa overlap. Contains Pfam match to FT entry PF00206 lyase_1, Lyase and match to Prosite entry FT PS00163 Fumarate lyases signature" FT /db_xref="GOA:Q9FBN4" FT /db_xref="InterPro:IPR004647" FT /db_xref="UniProtKB/TrEMBL:Q9FBN4" FT /protein_id="CAC05889.1" FT /translation="MGEMPEFAYTDLLPQGEDTTPYRLVTAEGVATFEADGRTFLKVEP FT EALRKLAEEAVHDIQHYLRPAHLAQLRRIIDDPEASGNDKFVALDLLKNANIAAAGVLP FT MCQDTGTAIVMGKRGQNVLTEGGDEEALSRGIYDAYKNLNLRYSQMAPLTMWEEKNTGS FT NLPAQIELYATDGGAYKFLFMAKGGGSANKSFLYQETKAVLNESSMMKFLEEKIRSLGT FT AACPPYHLAIVVGGTSAEYALKTAKYASAHYLDEIPAEGSELGHGFRDKELEEKVFELT FT QKIGIGAQFGGKYFCHDVRVVRLPRHGASCPVAIAVSCSADRQAVAKITAEGVFLEQLE FT TDPARFLPETTDEHLEEEGDVVKVDLNQPMDDILAELTRHPVKTRLSLTGPLVVARDIA FT HAKIKERLDAGEEMPQYLKDHPVYYAGPAKTPEGYASGSFGPTTAGRMDSYVEQFQAAG FT GSKVMLAKGNRSKQVTDACDAHGGFYLGSIGGPAARLAQDCIKKVEVVEYEELGMEAVW FT KIEVEDFPAFIVVDDKGNDFFQDPAPAPTFTTIPVRGPGLA" FT misc_feature complement(113925..114269) FT /note="Pfam match to entry PF00206 lyase_1, Lyase, score FT 61.10, E-value 2.9e-16" FT misc_feature complement(114015..114044) FT /note="PS00163 Fumarate lyases signature" FT RBS complement(115420..115423) FT CDS 115654..116337 FT /transl_table=11 FT /gene="SCO5045" FT /gene_synonym="SCK7.18" FT /product="conserved hypothetical protein" FT /note="SCK7.18, conserved hypothetical protein, len: 227 FT aa; similar to TR:CAB88834 (EMBL:AL353832) Streptomyces FT coelicolor hypothetical 30.8 kDa protein SCE6.30c, 277 aa; FT fasta scores: opt: 403 z-score: 468.8 E(): 1.2e-18; 38.6% FT identity in 220 aa overlap" FT /db_xref="InterPro:IPR012551" FT /db_xref="UniProtKB/TrEMBL:Q9FBN3" FT /protein_id="CAC05890.1" FT /translation="MDLHKHAPAAAPRTSELRASDADRDRVADMLREALAEGRLTADEH FT AERVEGVLAAKTVGELDVFVRDLPAAHRGRETTAPAPHRPTAGAIPAEPDENVVAVFSS FT AVRKGRWRANRRIHAYAVFGSIEIDLSEAVFEYQQVVIKAFSVFGSVEVRVPENVSVRG FT AGGSVLGSFEVHTLDSSEAEAPVIYVDGWAVLGSVEARPKRGKVVADILDRVHRRVEKG FT LRKHV" FT misc_feature 116087..117329 FT /note="previously sequenced DNA fragment. EMBL:AJ239088 FT Streptomyces coelicolor wblI gene for hypothetical protein" FT RBS 116430..116435 FT CDS 116443..116820 FT /transl_table=11 FT /gene="SCO5046" FT /gene_synonym="wblI" FT /gene_synonym="SCK7.19" FT /product="hypothetical protein" FT /note="SCK7.19, wblI, len: 125 aa; identical to previously FT sequenced TR:Q9X953 (EMBL:AJ239088) Streptomyces coelicolor FT hypothetical 13.9 kDa protein WblI, 125 aa and to TR:O88103 FT (EMBL:AJ010601) Streptomyces coelicolor WhiD protein, 112 FT aa; fasta scores: opt: 297 z-score: 395.0 E(): 1.6e-14; FT 46.7% identity in 105 aa overlap" FT /db_xref="InterPro:IPR003482" FT /db_xref="UniProtKB/TrEMBL:Q9X953" FT /protein_id="CAC05891.1" FT /translation="MLQPPHSSLQVAAVPAQRVPVRDRDQDAPWHTEAVCRRDEAGLFF FT APSKEPTAARLSREEAAKRVCARCPVMVECREHALLQPEPYGVWGGLTAAERRVVLARR FT RRRDVELRNAARTTGRIAAAG" FT CDS complement(117077..118108) FT /transl_table=11 FT /gene="SCO5047" FT /gene_synonym="SCK7.20c" FT /product="conserved hypothetical protein GlpX" FT /note="SCK7.20c, conserved hypothetical protein, len: 343 FT aa; similar to SW:GLPX_ECOLI (EMBL:Z11767) Escherichia coli FT hypothetical protein GlpX, 336 aa; fasta scores: opt: 789 FT z-score: 868.1 E(): 0; 46.5% identity in 325 aa overlap" FT /db_xref="GOA:Q9FBN2" FT /db_xref="HSSP:1NI9" FT /db_xref="InterPro:IPR004464" FT /db_xref="UniProtKB/TrEMBL:Q9FBN2" FT /protein_id="CAC05892.1" FT /translation="MTEHHLPSELDVPSEAPDRNLAMELVRVTEAAAMAAGRWVGRGDK FT NGADGAAVRAMRTLVHTVSMNGVVVIGEGEKDEAPMLFNGERVGDGTGAEVDIAVDPID FT GTTLTANGMTNAIAVLAAAERGSMFDPSAVFYMDKLVTGPEAADFVDINAPVAVNIRRI FT AKAKRRTPEDVTVVILDRPRHQGLIKEVRETGARIKLISDGDVAGSILALREGTGIDLL FT LGIGGTPEGIISACAVKCLGGTIQGKLWPKDAEERQRAVDAGHDLDRVLTTDDLVSGDN FT VFFVATGITDGELLRGVRYRSETATTDSIVMRSKSGTVRRIDSEHRLSKLRAYSAVDFD FT RAK" FT CDS 118244..118768 FT /transl_table=11 FT /gene="SCO5048" FT /gene_synonym="SCK7.21" FT /product="putative secreted protein" FT /note="SCK7.21, possible secreted protein, len: 174 aa. FT Contains possible N-terminal signal peptide sequence" FT /db_xref="UniProtKB/TrEMBL:Q9FBN1" FT /protein_id="CAC05893.1" FT /translation="MKGKQKSARDMILSLGVIVLAAGVIWIFIPHDDGEPDVKRVDYRV FT ELLTAQRAASYPVAAPEGLSEDWKPTSVRFRGDDSDAWHLGFRTPDGEYVAVEQSTKKP FT STFIHDASQGGQATERTEEIGGRTWTRYTGGRYDALVLDGTGDMKGATTVVAGTGSFEQ FT LGKMAAALKLA" FT CDS complement(118832..119422) FT /transl_table=11 FT /gene="SCO5049" FT /gene_synonym="SCK7.22c" FT /product="conserved hypothetical protein" FT /note="SCK7.22, hypothetical protein, len: 196 aa; similar FT to TR:P75894 (EMBL:AE000202) Escherichia coli hypothetical FT protein, 196 aa; fasta scores: opt: 466 z-score: 572.4 E(): FT 2e-24; 40.6% identity in 192 aa overlap and to FT SW:YDFN_BACSU (EMBL:AB001488) Bacillus subtilis putative FT NAD(P)H nitroreductase YdfN, 206 aa; fasta scores: opt: 133 FT z-score: 170.9 E(): 0.047; 23.1% identity in 199 aa FT overlap. Contains Pfam match to entry PF00881 FT Nitroreductase, Nitroreductase family. Similar also to FT TR:Q9FBV0 (EMBL:AL391072) Streptomyces coelicolor putative FT nitroreductase SC9A4.03c, 202 aa; fasta scores: opt: 599 FT Z-score: 706.0 E(): 1.1e-31; 49.474% identity in 190 aa FT overlap" FT /db_xref="GOA:Q9FBN0" FT /db_xref="InterPro:IPR000415" FT /db_xref="UniProtKB/Swiss-Prot:Q9FBN0" FT /protein_id="CAC05894.1" FT /translation="MSLVLDPAAQDLLFREARTANTFTDEPVTDEQVQAIYDLVKYGPT FT AFNQSPLRITLVRSPEARERLVAHMAEGNRPKTAAAPLVAILSADNEFHEELPELFPHF FT PAAKDAFFSERPVREGAATLNAALQAAYFIVGVRAAGLAAGPMTGLDFEGVRKEFLDDD FT HTPLMVVNIGRPGPDAWFPRSPRLAYDQVVTTV" FT misc_feature complement(118937..119341) FT /note="Pfam match to entry PF00881 Nitroreductase, FT Nitroreductase family, score 10.40, E-value 0.00063" FT CDS 119640..120971 FT /transl_table=11 FT /gene="SCO5050" FT /gene_synonym="SCK7.23" FT /product="putative nucleotide-sugar dehydrogenase" FT /note="SCK7.23, possible nucleotide-sugar dehydrogenase, FT len: 443 aa; similar to TR:CAB82012 (EMBL:AL161755) FT Streptomyces coelicolor putative nucleotide-sugar FT dehydrogenase SCD63.05c, 405 aa; fasta scores: opt: 736 FT z-score: 812.9 E(): 0; 36.2% identity in 423 aa overlap. FT Contains Pfam match to entry PF00984 UDPG_MGDP_dh, FT UDP-glucose/GDP-mannose dehydrogenase family" FT /db_xref="GOA:Q9FBM9" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9FBM9" FT /protein_id="CAC05895.1" FT /translation="MKFKSDSSHFDVSGPTVAVVGLGYVGLPTALALCDAGATVIGVDS FT SPERLRDIARGAVDLLPLHHAQLACASAGDRFRLTPDATAVRDADAVVICVPTPVDARR FT RPDLAALSAACASVVEHAVPGQLIVLTSTSYVGTTRDLLVEPLRARGLTVDEDVYVAFA FT PERIDPGNERHTPERTPRLVGGAGPRSSRAAADLLAPTASAVRTVPDPETAEMAKLWEN FT TYRAVNIALANELADACHSLGLAPAPVIEAAATKPYGFMPFYPGPGVGGHCIPCDPHYL FT LWQLGKVRQQAPLVATALAANSRRPARITERALDLLADSAVPAHGARVLLIGVAYKEGV FT ADVRESPALEILAGLAEAGAHVAYCDPLVPSLRVGADALHHLPDPHTRPWDLVVLNTVH FT PVHDLTWLCADDAPPVLDTRQRGPLTKAAARAATGVPPAAEATA" FT misc_feature 119682..120893 FT /note="Pfam match to entry PF00984 UDPG_MGDP_dh, FT UDP-glucose/GDP-mannose dehydrogenase family, score 293.40, FT E-value 2.7e-84" FT RBS 120956..120960 FT CDS 120968..122431 FT /transl_table=11 FT /gene="SCO5051" FT /gene_synonym="SCK7.24" FT /product="putative glycosyltransferase" FT /note="SCK7.24, possible glycosyltransferase, len: 487 aa; FT similar to SW:NODC_RHIME (EMBL:X01649) Rhizobium meliloti FT N-acetylglucosaminyltransferase (EC 2.4.1.-) NodC, 426 aa; FT fasta scores: opt: 377 z-score: 447.1 E(): 2e-17; 29.6% FT identity in 433 aa overlap. Contains Pfam match to entry FT PF00535 Glycos_transf_2, Glycosyl transferases and possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9FBM8" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q9FBM8" FT /protein_id="CAC05896.1" FT /translation="MTVLRPGHGPAAPVRSAARHRLGTRLDALDPRVRRDVVRLLTLLA FT LLPLLLLLARGAVRLPHAFDPLALYGLAVLAGTVCLLHLAYSRYDDPAVRPLRSRPRHA FT EAFPALPARPRVSFLLAVRNERAHIEACVRSMAGVDYPDVQLVVVDDASDDGTPDVLER FT LAAELPLTLIRLEENLGKKGALVRACAVADGDVLLFTDSDCVVAPDAVRHCVTALVRHP FT ELGAVGGHCRALNTDAGLLARVQDIWYEGQFRISKAAEAAFGSVTCVSGPLAAFRREAV FT WNYLPAWAEDRFLGAPFRFATDRQLTGYVLGQAWHGRALKDRHADSPFVRDHDYPELRW FT EVGYTRAARVWTRVPSRPGSFLRQQIRWKKSFIRNLFFTGRFMWRRGPAAAALYYGHAL FT WVIAAPVLVVRHLLWAPLHLAGPLTLLYLGGVVLKGCVWGLAYRLDHPGDRAWRCRPLM FT SLLSCCVLAWLLPYALLTLRRGVWSRSAA" FT misc_feature 121316..121822 FT /note="Pfam match to entry PF00535 Glycos_transf_2, FT Glycosyl transferases, score 77.20, E-value 3.3e-19" FT RBS 122417..122421 FT CDS 122428..122535 FT /transl_table=11 FT /gene="SCO5052" FT /gene_synonym="SCK7.25" FT /product="putative membrane protein" FT /note="SCK7.25, possible membrane protein, len: 35 aa. FT Doubtful CDS. Contains possible hydrophobic membrane FT spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9FBM7" FT /protein_id="CAC05897.1" FT /translation="MRVLLRGLGRSLAVGLTCAAVALVYVFVVTRGRWL" FT CDS 122532..124091 FT /transl_table=11 FT /gene="SCO5053" FT /gene_synonym="SCK7.26" FT /product="putative secreted protein" FT /note="SCK7.26, possible secreted protein, len: 519 aa. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="GOA:Q9FBM6" FT /db_xref="InterPro:IPR002509" FT /db_xref="UniProtKB/TrEMBL:Q9FBM6" FT /protein_id="CAC05898.1" FT /translation="MSSDGSRGNRPRRMPDGRPLLRAALGLLTAAVVALPFTAAWQYDT FT LRRAVAEQAAPPAPSSGDGGPGLGADAEPAPARNAPVVLAYHDVGPDDRSRYTVSPEHF FT DAQLRALRDAGYRTLTTREFTGFLRTGRTPGPRTVHLTFDDGTHGLWTHADPVLARYGM FT KAAAYLITGQVGTHRPYYLSWPEVERMARSGRWDFQAHTHLSHERAAVDAAGHERSVFT FT NRLWLADEGRVETSDEYRRRVAADLDRSIRDLVRHDLPRPRLFAYPFSERLDESNLGAR FT DADALRSMLRERFTATLTNSAARPLPAGPRAAAAGQVQRLEVTRDTTAAGLLRELGRWA FT TVTPQDADRPLAHPAHWQTTGATGQAGPGMLTGGSRPPAGTAYASADYRPFATADWTDY FT RLRAAVGGLHGTSNSAGITLRAGSGHPVSLSVGHHTASLTTADPETTGDRRSCRLKPSA FT THRITVSVTPRHVRVSVDGETCAAVRAGRWRVAEGAGGFSLSVRNDGPERQWPRFTSLK FT VR" FT CDS 124102..124416 FT /transl_table=11 FT /gene="SCO5054" FT /gene_synonym="SCK7.27" FT /product="hypothetical protein SCK7.27" FT /note="SCK7.27, unknown, len: 104 aa" FT /db_xref="UniProtKB/TrEMBL:Q9FBM5" FT /protein_id="CAC05899.1" FT /translation="MRPPITSRAGRGPKSTTPLVTRTPHLVPRERIDMTATVKGPASYF FT PSIEKKYGRPVAEWKDLIRSSPLTKHMELVAWLKAEHGLGHGHANALVAHTLAEGPAKG FT " FT CDS complement(124413..124679) FT /transl_table=11 FT /gene="SCO5055" FT /gene_synonym="SCK7.28c" FT /product="putative exoribonuclease" FT /note="SCK7.28c, possible exoribonuclease small subunit, FT len: 88 aa; similar to SW:EX7S_ECOLI (EMBL:D00694) FT Escherichia coli exodeoxyribonuclease small subunit (EC FT 3.1.11.6) XseB, 79 aa; fasta scores: opt: 129 z-score: FT 174.2 E(): 0.031; 35.3% identity in 68 aa overlap and to FT TR:Q9X784 (EMBL:AL049491) Mycobacterium leprae putative FT exodeoxyribonuclease small subunit XseB, 87 aa; fasta FT scores: opt: 231 z-score: 293.6 E(): 7e-09; 55.1% identity FT in 78 aa overlap" FT /db_xref="GOA:Q9FBM4" FT /db_xref="InterPro:IPR003761" FT /db_xref="UniProtKB/Swiss-Prot:Q9FBM4" FT /protein_id="CAC05900.1" FT /translation="MTSEVEQPTAMSEALGYEQARDELIEVVRRLEAGGTTLEESLALW FT ERGEELAEVCRRRLDGARARLDAALAEEADPEDGASGADGGGA" FT CDS complement(124689..125897) FT /transl_table=11 FT /gene="SCO5056" FT /gene_synonym="SCK7.29c" FT /product="putative exoribonuclease large subunit" FT /note="SCK7.29c, possible exoribonuclease large subunit, FT len: 402 aa; similar to TR:O53456 (EMBL:AL021897) FT Mycobacterium tuberculosis exonuclease VII large subunit FT XseA or MTV017.61c, 415 aa; fasta scores: opt: 1318 FT z-score: 1486.0 E(): 0; 52.3% identity in 407 aa overlap FT and to SW:EX7L_ECOLI (EMBL:J02599) Escherichia coli FT exodeoxyribonuclease large subunit (EC 3.1.11.6) XseA, 456 FT aa; fasta scores: opt: 610 z-score: 689.7 E(): 6e-31; 30.8% FT identity in 413 aa overlap" FT /db_xref="GOA:Q9FBM3" FT /db_xref="InterPro:IPR004365" FT /db_xref="UniProtKB/Swiss-Prot:Q9FBM3" FT /protein_id="CAC05901.1" FT /translation="MAANSTPEGPLPVGEVSRLIGGWIDRLGAVWVEGQITQLSRRPGA FT GVVFLTLRDPSYDISVSVTCYRQVFDAVADVVGEGARVVVHAKPEWYAPRGQLSLRAAE FT IKPVGVGELLARLEQLKKALAREGLFAAERKQPLPFLPQLIGLVCGRASAAERDVLENA FT RHRWPAVRFEVRNVPVQGVHAVPQVVQAVKELDARDDVDVIVVARGGGSVEDLLPFSDE FT QLVRAVAACRTPVVSAIGHEPDSPLLDLVADLRASTPTDAAKKVVPDVGEEYERVRLLR FT DRARRCVAAFVDREERGLAHALARPSIQDPHRMIEERAEQVTALLDRGRRSLRHHLDRA FT DSELTHTHARVVALSPAATLKRGYAVLQRADGHAVRDPGEVEPGETLRARVSEGDFSVR FT VDA" FT repeat_region 126052..126076 FT /note="3x degenerate repeat unit: FT CAGCGCG(T/C)GCCGCGCGTGTGT(C/T)GCC" FT repeat_region 126162..126186 FT /note="3x degenerate repeat unit: FT CAGCGCG(T/C)GCCGCGCGTGTGT(C/T)GCC" FT repeat_region 126272..126296 FT /note="3x degenerate repeat unit: FT CAGCGCG(T/C)GCCGCGCGTGTGT(C/T)GCC" FT CDS complement(126474..127856) FT /transl_table=11 FT /gene="SCO5057" FT /gene_synonym="SCK7.30c" FT /product="putative amino acid permease" FT /note="SCK7.30c, possible amino acid permease, len: 460 aa; FT similar to SW:MMUP_ECOLI (EMBL:D83536) Escherichia coli FT probable S-methylmethionine permease MmuP, 475 aa; fasta FT scores: opt: 345 z-score: 390.5 E(): 2.8e-14; 23.3% FT identity in 408 aa overlap and to TR:P74848 (EMBL:X99945) FT Salmonella typhimurium amino acid permease YeeF like FT protein, 448 aa; fasta scores: opt: 705 z-score: 792.4 E(): FT 0; 32.0% identity in 416 aa overlap. Contains Pfam match to FT entry PF00324 aa_permeases, Amino acid permease and FT possible hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9FBM2" FT /db_xref="InterPro:IPR004841" FT /db_xref="UniProtKB/TrEMBL:Q9FBM2" FT /protein_id="CAC05902.1" FT /translation="MAQSGTTAPEAGGEERLRRSLGFRDLVVYGLLFIAPMAPVGVFGT FT LDAKSHGAVALVYLVATVAMAFTAFSYAQMVRVVPQAGSVFAYARAGLGNGAGFVAGWM FT AMLDYILIPAVAYLFSGIAMEALVPEVSRWVWTAIAVVVTTLLNLWGVRTAARVGFLVL FT AMEIVVLLVFVATAIVVLAQDGAERDWLSPLSGDGTQGAFALSAVVGAVSVAVLSYLGF FT DAIATFAEEVTGGSAKVARALLFCLALAGVLFVAQTYLVALLEPVSSAQLAAEPERQGS FT AFYDAVDVSVGTWLHDLVAVSKAIGAAFAALAGQAAAGRLLFAMGRDRRLPGVLARTDA FT GVPRVALLVSAVITMAAAVWAARRDDGLDHLVSVVDVGALTAFTLLHASVVGWFVVRRG FT GGRVIWWRHLLVPVLGAAITIAVIVEASGTAQVVGAIWLAVGLVVLAAQWRGRRDAETT FT GA" FT misc_feature complement(126498..127733) FT /note="Pfam match to entry PF00324 aa_permeases, Amino acid FT permease, score -171.30, E-value 2.7e-06" FT RBS complement(127861..127865) FT CDS 127985..129001 FT /transl_table=11 FT /gene="SCO5058" FT /gene_synonym="lytB" FT /gene_synonym="SCBAC20F6.01" FT /gene_synonym="SCK7.31" FT /product="hypothetical protein" FT /note="SCBAC20F6.01, lytB, len: >148 aa; highly similar to FT C-terminal region of SW:LYTB_ECOLI (EMBL:X54945) FT Escherichia coli LytB protein LytB or B0029, 316 aa; fasta FT scores: opt: 434 Z-score: 512.5 bits: 101.9 E(): 5.9e-21; FT 51.145% identity in 131 aa overlap. Contains Pfam match to FT entry PF02401 LYTB, LytB protein" FT /note="SCK7.31, hypothetical protein (fragment), len: >224 FT aa; similar to SW:LYTB_ECOLI (EMBL:AE000113) Escherichia FT coli regulator, control of stringent response; involved in FT penicillin tolerance LytB protein, 316 aa; fasta scores: FT opt: 781 z-score: 922.7 E(): 0; 53.2% identity in 216 aa FT overlap" FT /db_xref="GOA:Q9FBM1" FT /db_xref="InterPro:IPR003451" FT /db_xref="UniProtKB/Swiss-Prot:Q9FBM1" FT /protein_id="CAD55221.1" FT /translation="MGAMTASPGRRVLLAAPRGYCAGVDRAVIAVEKALEQYGAPVYVR FT HEIVHNKYVVQTLEKKGAIFVERTEEVPEGNIVMFSAHGVAPVVHEEAERGKLATIDAT FT CPLVTKVHKEAVRFANDDYDILLIGHEGHEEVIGTSGEAPDHIQLVDGPEDVAKVEVRD FT PSKVVWLSQTTLSVDETMETVDALKDKFPQLISPPSDDICYATQNRQLAVKQMGAEAEL FT VIVVGSRNSSNSKRLVEVAKQAGSRAAYLVDFADEIDETWLDGVTTVGVTSGASVPDVL FT VEQVLEWLSRRGFEDVEIVKAAEESIIFSLPKELRRDLREEAASLVAERGGSGTAGA" FT misc_feature 128555..128860 FT /note="Pfam match to entry PF02401 LYTB, LytB protein, FT score -87.40, E-value 2.5e-05" FT CDS 129055..129795 FT /transl_table=11 FT /gene="SCO5059" FT /gene_synonym="ppgK" FT /gene_synonym="SCBAC20F6.02" FT /product="polyphosphate glucokinase" FT /note="SCBAC20F6.02, ppgK, polyphosphate glucokinase, len: FT 246 aa; highly similar to SW:PPGK_MYCTU (EMBL:U44834) FT Mycobacterium tuberculosis polyphosphate glucokinase (EC FT 2.7.1.63) PpgK or RV2702 or MTCY05A6.23, 265 aa; fasta FT scores: opt: 912 Z-score: 1042.8 bits: 200.5 E(): 1.7e-50; FT 57.322% identity in 239 aa overlap. Contains Pfam match to FT entry PF00480 ROK, ROK family" FT /db_xref="GOA:Q9ADE8" FT /db_xref="InterPro:IPR000600" FT /db_xref="UniProtKB/TrEMBL:Q9ADE8" FT /protein_id="CAC37447.1" FT /translation="MQIFGVDIGGSGIKGAPVDLDRGDLAQERCKVLTPHPATPDGVAD FT GVKQVVEHFGWTGRVGLTFPGVVTGGATVRTAANVDKGWVDTDARALFAERLGGLDVTV FT VNDADAAGVAEMHFGAGRGRKGTVVLLTFGTGIGSAVFTDGLLVPNTELGHLELDGHDA FT EKRASSKVKDDHDMSWEHWAHRVQKYLAHVEMLFSPELFIIGGGVSRKSQKFLPHIKDV FT RAEIVPAQLQNNAGIVGAAMHAAG" FT misc_feature 129067..129477 FT /note="Pfam match to entry PF00480 ROK, ROK family, score FT 21.60, E-value 2.4e-05" FT CDS complement(129806..130408) FT /transl_table=11 FT /gene="SCO5060" FT /gene_synonym="SCBAC20F6.03c" FT /product="putative integral membrane protein" FT /note="SCBAC20F6.03c, possible integral membrane protein, FT len: 200 aa. Contains possible hydrophobic membrane FT spanning regions and high G+C content in N-terminal region" FT /db_xref="UniProtKB/TrEMBL:Q9ADE7" FT /protein_id="CAC37448.1" FT /translation="MEQHRTRPAQYGPRRSGAPLPAQGRGGAVARPPAGRVGPPAGRRP FT EPVRPAPGAPSPVARVVRALRGMPNPRLTGLGSGLFCAAVMTLLGFLDELLFGSSLTAY FT GVLFVPVSLLTALWVRRGDLLTAPVVVPIAFAVGLVPVAESGDGGLGGRLMGIVTALAT FT EAGWLYGGTLVAGSTVIVRRIRLMRRRAAAARNRPPA" FT misc_feature complement(130174..130384) FT /note="high G+C content region (82.46%)" FT CDS 130594..131682 FT /transl_table=11 FT /gene="SCO5061" FT /gene_synonym="SCBAC20F6.04" FT /product="putative ATP/GTP binding protein" FT /note="SCBAC20F6.04, possible ATP/GTP binding protein, len: FT 362 aa; highly similar to SW:YCHF_ECOLI (EMBL:AE000219) FT Escherichia coli probable GTP-binding protein in treA-pth FT intergenic region YchF or Gtp1 or B1203, 362 aa; fasta FT scores: opt: 1193 Z-score: 1225.2 bits: 235.3 E(): 1.2e-60; FT 51.944% identity in 360 aa overlap. Contains Pfam match to FT entry PF01018 GTP1_OBG, GTP1/OBG family and match to FT Prosite entry PS00017 ATP/GTP-binding site motif A FT (P-loop)" FT /db_xref="GOA:Q9ADE6" FT /db_xref="HSSP:1JAL" FT /db_xref="InterPro:IPR002917" FT /db_xref="UniProtKB/TrEMBL:Q9ADE6" FT /protein_id="CAC37449.1" FT /translation="MSLTIGIVGLPNVGKSTLFNALTKNDVLAANYPFATIEPNVGVVG FT VPDPRLTKLAEIFSSEKILPATVDFVDIAGIVRGASEGEGLGNKFLANIRESDAICQVI FT RAFKDENVVHVDGKVSPKDDIETINTELILADLQTIEKVLPRLQKESRIKKDVAPKVKA FT VEEAKEILEKGDTLFSQGILQGSERAELLHDLHLLTTKPFLYVFNVDEDELTDDDFKSE FT QRALVAPAEAIFLNAKLEADLAELDEDEALELLQSVGQDEPGLATLAHVGFRTLGLQTY FT LTAGPKESRAWTIKKGATAPEAAGVIHTDFQKGFIKAEVISFDDLVETGSVTEARAKGK FT ARMEGKEYVMRDGDVVEFRFNV" FT misc_feature 130606..130725 FT /note="Pfam match to entry PF01018 GTP1_OBG, GTP1/OBG FT family, score 15.50, E-value 0.00092" FT misc_feature 130618..130641 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(131804..132196) FT /transl_table=11 FT /gene="SCO5062" FT /gene_synonym="SCBAC20F6.05c" FT /product="hypothetical protein" FT /note="SCBAC20F6.05c, hypothetical protein, len: 130 aa; FT similar to TR:Q9X8E7 (EMBL:AL049573) Streptomyces FT coelicolor hypothetical 16.4 kDa protein SCE39.24, 148 aa; FT fasta scores: opt: 257 Z-score: 327.8 bits: 66.5 E(): FT 1.1e-10; 39.394% identity in 132 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9ADE5" FT /protein_id="CAC37450.1" FT /translation="MPGTLLLDSEGLSKLYRKDRTVMALVQAAAEEGVRVATSAMTTLE FT ADYERIHPARIKWILSRVDVHDVTKEITDQAAALLRAHRLHGHTYAIDAAFAVIARDAS FT RPVTVLTSDPEDLTLLCGPSVGVVKV" FT CDS complement(132196..132447) FT /transl_table=11 FT /gene="SCO5063" FT /gene_synonym="SCBAC20F6.06c" FT /product="hypothetical protein" FT /note="SCBAC20F6.06c, hypothetical protein, len: 83 aa; FT similar to TR:Q9XAG7 (EMBL:AL079356) Streptomyces FT coelicolor hypothetical 8.8 kDa protein SC6G9.07, 84 aa; FT fasta scores: opt: 167 Z-score: 224.6 bits: 45.9 E(): FT 6.3e-05; 43.103% identity in 58 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9ADE4" FT /protein_id="CAC37451.1" FT /translation="MSGSRKYSISLPEDLAEAVRAHVGPGGFSAYVAEALEQRVAMDKL FT REIVADFETDNEALTHEEVEAARALLRHDHRQAGGAAA" FT CDS 132446..134848 FT /transl_table=11 FT /gene="SCO5064" FT /gene_synonym="SCBAC20F6.07" FT /product="putative bifunctional protein" FT /note="SCBAC20F6.07, possible bifunctional protein, len: FT 800 aa; N-terminal domain does not present similarity to FT any known protein and C-terminal half is similar to the FT C-terminal domain of may prokaryotic putative helicases, FT e.g. TR:Q9CE08 (EMBL:AE006434) Lactococcus lactis (subsp. FT lactis) SWI/SNF family helicase Snf, 1034 aa; fasta scores: FT opt: 317 Z-score: 332.6 bits: 72.8 E(): 6.1e-11; 29.817% FT identity in 436 aa overlap. Contains Pfam match to entry FT PF00176 SNF2_N, SNF2 and others N-terminal domain and Pfam FT match to entry PF00271 helicase_C, Helicase conserved FT C-terminal domain" FT /db_xref="GOA:Q9ADE3" FT /db_xref="InterPro:IPR003583" FT /db_xref="UniProtKB/TrEMBL:Q9ADE3" FT /protein_id="CAC37452.1" FT /translation="MVPILPAVVSLGGEWLPRGSVDQQGAVNARRGPVWAVERCGEGQR FT GAGSVGRGERDTVARGTRLYEAAQAVVGDHARAVEAVRAALKPIHDEAVKRELDAIPVA FT RLQDVTEGRLRLGSVEKSGLRTLGRVLEAGPYRLRQIPGVGQRTVDQILAAARRLSEAV FT HETVAVHIDVDRPEPRTTALVMALHVLVEAGPEARRAVDKATVLTERLGPLLADAGPAA FT GRVRMLLAGREKKARAWAAVAATRSLVDEAEQAGLPGLLAQASVDLLRGTASDVAAWVD FT FELRSAEYYSLLAEISGRPPDAAAVEGFLPDEVAERVRTQHLDDTHRRVSLRGYQAFGA FT RFALAQRKVILGDEMGLGKTIQAIAVLAHLAAEGQSHFMVVCPASVLVNWTREIEARSA FT LRVMVLHGPDRHYAFADWKGRGGVGVTTFDALRGFPAPGGGEVGLLVVDEAHSVKNPKA FT KRSQAVGLWAERCERTLFMTGTPMENRVAEFRNLVQMLDGDVADSLGERDALAGSVTFR FT KAVAPVYLRRNQEDVLTELPSLQQTDEWEELSASDEEAYREAVRAGNFMAMRRAAYMSS FT GNSAKLERLREIVQEAGENGQKTVVFSNFKDVLAVVKEALAVETTRVTPVFGPLTGGVP FT AQRRQEIVDDFAGVQGPAVLLGQIQAAGVGLNMQAASVVVICEPQIKPTIEHQAVARAH FT RMGQVRPVRVHRLLATGGVDERMVKMLEAKTRLFDAYARRSAVAEATPDAVDVSDTELA FT RRIVEEEQARLGMTDERPTSSEWGVPRSAASPQDPLNGRRESTNANE" FT misc_feature 133448..133924 FT /note="Pfam match to entry PF00176 SNF2_N, SNF2 and others FT N-terminal domain, score 94.40, E-value 5.5e-25" FT misc_feature 134285..134536 FT /note="Pfam match to entry PF00271 helicase_C, Helicase FT conserved C-terminal domain, score 31.50, E-value 2e-05" FT CDS complement(134937..137768) FT /transl_table=11 FT /gene="SCO5065" FT /gene_synonym="SCBAC20F6.08c" FT /product="putative transcriptional regulator" FT /note="SCBAC20F6.08c, possible transcriptional regulator, FT len: 943 aa; similar to many putative transcriptional FT regulatory proteins, e.g. TR:Q9XAT8 (EMBL:U95170) FT Rhodococcus erythropolis ThcG, 927 aa; fasta scores: opt: FT 1419 Z-score: 1371.5 bits: 265.1 E(): 8.4e-69; 35.446% FT identity in 931 aa overlap. Contains Pfam match to entry FT PF00196 GerE, Bacterial regulatory proteins, luxR family FT and matches to Prosite entries PS00017 ATP/GTP-binding site FT motif A (P-loop) and PS00622 Bacterial regulatory proteins, FT luxR family signature. Also contains possible FT helix-turn-helix motif at residues 893..914 (+3.76 SD)" FT /db_xref="GOA:Q9ADE2" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9ADE2" FT /protein_id="CAC37453.1" FT /translation="MKNGERARAGHGSPAAPGPTAGPGPAPAPGPTVVGREAEIAEIRS FT RIAADRSHSSVLIVEGDPGAGKSVLLDLAVRLTRGTGQRVLRAVGSESEASLAFAGLHQ FT MLRPVLDDLGGLPARQRSALRTALGLAEDAEDAADTPDALLVGLAVLTLVSDLSEPAPL FT LVVVDDAQWIDRASLDVLSFLARRMAGEPVTLLMGVRAAAVLPGFDKGYERLEIGPLSG FT DAANRLLDEQPKRPTGRTRARILREAAGNPLALVELARATADREPEGSGVEGPLPVTDR FT LEGIFARHVRHLPEATRRALLLLAAADAADAPAAARGLPEAADTVWAPAERAGLVRQDG FT TGVSFRHPLVRSAVYHAAPFEQRRRAHLALARQLGEEPDRRAWHLAAAAVRPDEQVSAA FT LRETAGRARRRGGHAAAAAALERAAELSPHRADQARLLADAADTAVFTGQLGWVEHLAA FT GARERSDDPALIGRAALATGRLLTLGPHHTAAFALLSRVADEAAATRSPRLLDALAAAA FT VVRYYSGEESQRQRIEALLADVPDSAAGGALRAWVLAVSDPSGAGASLAPALPRLIAAA FT KGEAGSLTALAVVAWLLDRTPLAARTFDEAFGRWQAHGPLPAGLACAAGWAYLEQGRWA FT DARSVAAEIAEVASGAGLDHAEACARTLDATVLALLGEPAEARGSAERALALVAPLESR FT SVAVLARRALGLAAVAEGDYDSAYAQFRAAFTEDGDLVHYHVSPTVLAELAAAAVRRGH FT REPAARLLERSARHLGPGMSARLFLLVERGRALLAEPERAERHFRAALAGEAGEQWPFE FT RAQTRLDYGEWLRRQRRVAEARPLLTGALDTFRRLGARPWIDRAKAELRAAGIEADAAA FT PGALTELSPQQQQIVRLAAHGLTNREIGERLFLSPRTVGSHLYRVFPKLGITARAQLRD FT LLDDALQATGSAQ" FT misc_feature complement(134949..135146) FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 55.50, E-value FT 1.2e-12" FT misc_feature complement(135012..135095) FT /note="PS00622 Bacterial regulatory proteins, luxR family FT signature" FT misc_feature complement(137565..137588) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(137774..137777) FT RBS 138068..138071 FT CDS 138078..138992 FT /transl_table=11 FT /gene="SCO5066" FT /gene_synonym="SCBAC20F6.09" FT /product="putative beta-lactamase" FT /note="SCBAC20F6.09, possible beta-lactamase, len: 304 aa; FT similar to TR:Q9X7X2 (EMBL:AL049485) Streptomyces FT coelicolor putative beta-lactamase SC6E5.26c, 310 aa; fasta FT scores: opt: 598 Z-score: 696.3 bits: 136.9 E(): 3.4e-31; FT 53.115% identity in 305 aa overlap and to SW:BLA1_XANMA FT (EMBL:X75074) Xanthomonas maltophilia FT metallo-beta-lactamase L1 precursor (beta-lactamase, type FT II) (EC 3.5.2.6), 290 aa; fasta scores: opt: 146 Z-score: FT 175.9 bits: 40.6 E(): 0.033; 25.952% identity in 289 aa FT overlap. Contains Pfam match to entry PF00753 lactamase_B, FT Metallo-beta-lactamase superfamily and match to Prosite FT entry PS00136 Serine proteases, subtilase family, aspartic FT acid active site" FT /db_xref="GOA:Q9ADE1" FT /db_xref="InterPro:IPR000209" FT /db_xref="UniProtKB/TrEMBL:Q9ADE1" FT /protein_id="CAC37454.1" FT /translation="MDTITLGDVTVTRVREYYGPVGMTPEAFVPDSPAQAWDTHRSWLV FT PDFLDAETRIVNTAIQTWVLRSEGRTILVDTGVGNHKDRPYAPVWSRLETDFLANLARA FT GVQPEDVDIVINTHLHIDHVGWNTYLDGRTWVPTFPNATYLMAKADFDYWNPANEIKTL FT LGRGNQNVFEDSVAPVHEAGLTRLWEDGHRIDSNLRLELAPGHTPGSSVLRLESGSDRG FT LFVGDLMHSPIQIHEPDANSCFCEDPAEARATRRRLLGSAVDSNALVFPAHLGGHGAAE FT VVREGGKFAVKGWAPFTPYTPSV" FT misc_feature 138240..138896 FT /note="Pfam match to entry PF00753 lactamase_B, FT Metallo-beta-lactamase superfamily, score 53.00, E-value FT 6.4e-12" FT misc_feature 138288..138320 FT /note="PS00136 Serine proteases, subtilase family, aspartic FT acid active site" FT RBS 139001..139006 FT CDS 139015..140508 FT /transl_table=11 FT /gene="SCO5067" FT /gene_synonym="SCBAC20F6.10" FT /product="putative carboxylesterase" FT /note="SCBAC20F6.10, probable carboxylesterase, len: 497 FT aa; similar to SW:PNBA_BACSU (EMBL:U06089) Bacillus FT subtilis para-nitrobenzyl esterase (EC 3.1.1.*) PnbA, 489 FT aa; fasta scores: opt: 784 Z-score: 827.6 bits: 162.6 E(): FT 1.6e-38; 37.205% identity in 508 aa overlap. Contains 2x FT Pfam matches to entry PF00135 COesterase, Carboxylesterase FT and match to Prosite entry PS00122 Carboxylesterases type-B FT serine active site" FT /db_xref="GOA:Q9ADE0" FT /db_xref="HSSP:1QE3" FT /db_xref="InterPro:IPR019826" FT /db_xref="UniProtKB/TrEMBL:Q9ADE0" FT /protein_id="CAC37455.1" FT /translation="MNHHPEPVVTTAQGAVRGLRQEDGTAAFLNIPYAAPPLGAGRFAP FT PRPHEPWDGVRDATVPGPNAPQSERRLGSIDMAPYFGTGWSRGEDYLTVNVFTPATGAG FT DLPVMVFVHGGGFVAGSTRSAMYDGSAFARDGVVLVTLNYRLGIAGFLDIPGAPANRGL FT LDVVAALRWVRENVSAFGGNPHHVTLFGQSAGATVVGGVLATPEADGLFRRAIVQSGSG FT LGAFTPEQAARVTAAAAQALGVEPHVDAFAGIPDERLVEAASGLAGIDLRTGTHFDPLI FT GLSPFSLVLDTQPAASVAAGRAADVDLLVGTNTEEGNLYLVPVGKYATSTAADVDEAAA FT RAHPDPAQLVAAYRTSRPEATFAELRSAVMADALFGAGSRALASAHATHPRAATYAYEF FT AWRSRALDGELGATHAVELPFVFDLADRPELNGPAALLGPEQAPADLAARVHATWIRFA FT RTGDPGWDPYDTDRRATMRIDAEWSQTDDPRSKEREVWS" FT misc_feature 139033..139965 FT /note="Pfam match to entry PF00135 COesterase, FT Carboxylesterase, score 253.00, E-value 6e-73" FT misc_feature 139552..139599 FT /note="PS00122 Carboxylesterases type-B serine active site" FT misc_feature 140119..140502 FT /note="Pfam match to entry PF00135 COesterase, FT Carboxylesterase, score 47.70, E-value 3.2e-13" FT CDS complement(140516..141115) FT /transl_table=11 FT /gene="SCO5068" FT /gene_synonym="SCBAC20F6.11c" FT /product="putative tetR-family transcriptional regulator" FT /note="SCBAC20F6.11c, possible tetR-family transcriptional FT regulator, len: 199 aa; similar to many actinomycetes FT putative tetR-family transcriptional regulators, e.g. FT TR:Q9RJL5 (EMBL:AL121849) Streptomyces coelicolor putative FT tetR-family transcriptional regulator SCF6.16, 194 aa; FT fasta scores: opt: 419 Z-score: 483.9 bits: 96.4 E(): FT 2.3e-19; 38.095% identity in 189 aa overlap. Contains Pfam FT match to entry PF00440 tetR, Bacterial regulatory proteins, FT tetR family and possible helix-turn-helix motif at residues FT 36..57 (+4.64 SD)" FT /db_xref="GOA:Q9ADD9" FT /db_xref="InterPro:IPR012287" FT /db_xref="PDB:2REK" FT /db_xref="UniProtKB/TrEMBL:Q9ADD9" FT /protein_id="CAC37456.1" FT /translation="MSWENPGPPKRADARRNYDRIIEAAAAEVARHGADASLEEIARRA FT GVGSATLHRHFPSRWGLLQAVFQERVAQLCDEARSLAAEHPPATALTRWLTSLAVFGAV FT TRGAARSLLPATGTNTGAALDSRCEQLLTEAGADLLARAQEDGTVRDDVTALELLSLAN FT AVSLAAEHTPDAAHHATRLMGIALGGLGAPGPRPQG" FT misc_feature complement(140918..141055) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 52.60, E-value FT 5.2e-12" FT CDS 141271..142227 FT /transl_table=11 FT /gene="SCO5069" FT /gene_synonym="SCBAC20F6.12" FT /product="putative oxidoreductase" FT /note="SCBAC20F6.12, possible oxidoreductase, len: 318 aa; FT similar to many oxidoreductases/dehydratases, e.g. FT TR:Q9WX20 (EMBL:AL079345) Streptomyces coelicolor putative FT dehydrogenase SCE68.12c, 318 aa; fasta scores: opt: 998 FT Z-score: 1062.9 bits: 204.9 E(): 1.3e-51; 52.997% identity FT in 317 aa overlap. Contains Pfam match to entry PF00107 FT adh_zinc, Zinc-binding dehydrogenases" FT /db_xref="GOA:Q9ADD8" FT /db_xref="HSSP:1IYZ" FT /db_xref="InterPro:IPR013154" FT /db_xref="UniProtKB/TrEMBL:Q9ADD8" FT /protein_id="CAC37457.1" FT /translation="MRAVQFDRFGPPDVLRVNDVPAPRPGPGEVLVEVRAASVDAGETA FT FRAGRMRRVTRVRFPRGLGSDFAGRVAALGSGVRAWSVGDAVWGLMPHLTFGAIADYVA FT VPEQRLARAPQNLDLLEAAALPVVGTTAMTALSGKARLQPGERLLVRGATGGVGSVAVQ FT LGKALGAHVTALAAARNLDWITRLGADEAVDYRTTRPEDLDRFDVIVDVVGTDLGAYRK FT RLARGGRLVALSFDSDRVVSSMLGIALRAAATPRRVKMFSNNPSADRIAELTRAVEAGT FT IRPVVDTVFPMRDIAAVHQRLEAGGVRGKYVVDLRLP" FT misc_feature 141310..142215 FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score 182.30, E-value 8e-51" FT misc_feature 142241..147486 FT /note="previously sequenced DNA fragment. EMBL:X62373 FT S.coelicolor genes for hydroxyacyl-CoA dehydrogenase" FT CDS complement(142268..143452) FT /transl_table=11 FT /gene="SCO5070" FT /gene_synonym="SCBAC20F6.13c" FT /product="hydroxylacyl-CoA dehydrogenase" FT /note="SCBAC20F6.13c, ORFB hydroxylacyl-CoA dehydrogenase, FT len: 394 aa; identical to previously sequenced TR:Q53924 FT (EMBL:X62373) Streptomyces coelicolor hydroxylacyl-CoA FT dehydrogenase ORFB, 394 aa. There is an alternative start FT codon 120 base pairs upstream of the previously sequenced FT one" FT /db_xref="UniProtKB/TrEMBL:Q53924" FT /protein_id="CAC37458.1" FT /translation="MLSVGHGPRHVLVVARPHPDEPVGGATALALAELVAGGDRRSPAT FT DPEAVTWDIVLCLDPDGAALSEGIETATAGPAPSLASYYRAAFRPVAAEQPEWAPIVGR FT PLPESRALFDVIDDLRPVLQCSLHNVDAGGTWAQLTRDLPGLAAPFAASAAALGVPVQH FT GTYDALYWENPAPGIHVLPPPGSTARPAAGSEDIGLSTWCAPQRYGGATAIVEVPLWAT FT APADDPTPHADPARALRALSGLVREGGRQVTAVFERARGLLPAPEDSPPVRVLEWMAED FT LYDLVADSWGPLVRQAEAGPRTDGSPALTTAGIGALEVVARRQPLRAAGLLLRLLHAAD FT APAAAGLHHELDALFTAWCTDFETSLRLRWVPVHAQVELQARTVVAAAECALTP" FT CDS complement(143809..144249) FT /transl_table=11 FT /gene="SCO5071" FT /gene_synonym="SCBAC20F6.14c" FT /product="hydroxylacyl-CoA dehydrogenase" FT /note="SCBAC20F6.14c, ORFA hydroxylacyl-CoA dehydrogenase, FT len: 146 aa; identical to previously sequenced TR:Q53925 FT (EMBL:X62373) Streptomyces coelicolor hydroxylacyl-CoA FT dehydrogenase ORFA, 146 aa" FT /db_xref="UniProtKB/TrEMBL:Q53925" FT /protein_id="CAC37459.1" FT /translation="MTITALPTGLYAEVLSFYGHQMQKLDGRDFAGYAATFTEDGEFRH FT SPSLPAAHTRAGITAVLEDFHRKFDARKIQRRHWFDHTALSQASDGSITATSYCLVLTV FT HADVKAPEFGPSCLVHDVLVRGADGELLLRSRHVTHDHVFPA" FT misc_feature 144323..144841 FT /note="Pfam match to entry PF02737 3HCDH_N, FT 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain, score FT 78.20, E-value 1.7e-19" FT CDS 144323..145246 FT /transl_table=11 FT /gene="SCO5072" FT /gene_synonym="SCBAC20F6.15" FT /product="hydroxylacyl-CoA dehydrogenase" FT /note="SCBAC20F6.15, ORF1 hydroxylacyl-CoA dehydrogenase, FT len: 307 aa; identical to previously sequenced TR:Q53926 FT (EMBL:X62373) Streptomyces coelicolor hydroxylacyl-CoA FT dehydrogenase ORF1, 307 aa. Contains Pfam matches to FT entries PF02737 3HCDH_N, 3-hydroxyacyl-CoA dehydrogenase, FT NAD binding domain and PF00725 3HCDH, 3-hydroxyacyl-CoA FT dehydrogenase, C-terminal domain. Contains possible FT hydrophobic membrane spanning region" FT /db_xref="GOA:Q53926" FT /db_xref="HSSP:3HDH" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q53926" FT /protein_id="CAC37460.1" FT /translation="MSTVTVIGAGTIGLGWINLFSARGLTVRVNSRRPDVRRVVHEALE FT LFSPGRVDELAARIEYEPDVGRAVAGADVVSENAPDDLPLKQRLFAEIGAAAPDHALVL FT SSTSKLLPDELSRDMPGPGRLVVAHPFNPPHIVPLVEVVRGERTDPEAVERTLAFLASV FT GRTPVVVRRALPGFAANRLQSALLRESIHLVLEGVVTVEELDRIVTDSIGLRWSTIGPF FT HAFHLGGGPGGLRKWLEHLGSGLEQGWRGLGQPALTPQAVEALVAQTEAAYGHRPYAEL FT VRDRDDRHLAVLAALERTEQPQEETK" FT misc_feature 144848..145156 FT /note="Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA FT dehydrogenase, C-terminal domain, score -8.40, E-value FT 0.048" FT RBS 145233..145237 FT CDS 145243..146232 FT /transl_table=11 FT /gene="SCO5073" FT /gene_synonym="SCBAC20F6.16" FT /product="putative oxidoreductase" FT /note="SCBAC20F6.16, ORF2, possible oxidoreductase, len: FT 329 aa; identical to previously sequenced TR:Q53927 FT (EMBL:X62373) Streptomyces coelicolor genes for FT hydroxylacyl-CoA dehydrogenase ORF2, 329 aa. Contains Pfam FT match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases and match to Prosite entry PS01162 Quinone FT oxidoreductase / zeta-crystallin signature" FT /db_xref="GOA:Q53927" FT /db_xref="HSSP:1PQW" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q53927" FT /protein_id="CAC37461.1" FT /translation="MMRAVQFDRYGDPDVLYVAERPVPEPGPGQVRIAVDAVSVGHAQT FT QMRREAFPAPMWRPVFPVVLGGDVVGRITAVGPGVTALRPGDRVGAFTLYGAYAEQVVV FT DAVTVVPVPEELDAAEAAVLPGTGLIALGILRTGRLRKGETVLIHAAAGGVGHIAVQLA FT RAAGAGLIIGTAGAAAKREFARATGADAVVDHRSAHWADEVRELTGGRGPDLILDGIGA FT EVLEQGVGLLAPGGRLVFYGSSGGELAIPKVSVMDLIGIKYVTGFALSAWRGGRPQEYE FT AGVAELTRLLAEGQVTSAVHARLPLERAAEAHAVVEARAQLGRVVLVP" FT misc_feature 145285..146229 FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score 276.60, E-value 3.3e-79" FT misc_feature 145669..145734 FT /note="PS01162 Quinone oxidoreductase / zeta-crystallin FT signature" FT RBS 146285..146290 FT CDS 146299..146943 FT /transl_table=11 FT /gene="SCO5074" FT /gene_synonym="SCBAC20F6.17" FT /product="putative dehydratase" FT /note="SCBAC20F6.17, possible dehydratase, len: 214 aa; FT identical to previously sequenced TR:Q53928 (EMBL:X62373) FT Streptomyces coelicolor ORF 3, 214 aa. Similar to TR:Q56172 FT (EMBL:L37334) putative dehydratase from granaticin FT biosynthesis cluster of Streptomyces violaceoruber Tu22 FT (221 aa) fasta scores; opt: 349, Z-score: 400.9, E(): FT 1.1e-14, 35.465% identity (37.195% ungapped) in 172 aa FT overlap." FT /db_xref="UniProtKB/TrEMBL:Q9ADD7" FT /protein_id="CAC37462.1" FT /translation="MTSSLHHAIRLTTASAIALGGLVTLGTSAHAASVAVPYECRTWVQ FT GNTHPVYDYARGFDVSVPASVRAGKKFKATYDPDPITAFAEYNQIVNDVRIAYRIPDGA FT KVHKVRLTGGSGLGDSDVRVQVKGRDIVVSASGPFQGGVEFDLPTLKVTYKAPKTTGPL FT NFVSGGSGYEDPGFYWYRYQPILDEWGPFECFPDPAKPEAVLASTQVKKHK" FT RBS 146968..146971 FT CDS 146977..147897 FT /transl_table=11 FT /gene="SCO5075" FT /gene_synonym="ORF4" FT /gene_synonym="SCBAC28G1.01" FT /gene_synonym="SCBAC20F6.18" FT /product="putative oxidoreductase" FT /note="SCBAC28G1.01, possible oxidoreductase, previously FT sequenced as ORF4, len: 167 aa; identical to C-terminal FT region of previously sequenced TR:Q53929 (EMBL:X62373) FT Streptomyces coelicolor ORF4, 306 aa; fasta scores: opt: FT 1029 Z-score: 1146.7 bits: 219.4 E(): 2.9e-56; 95.808% FT identity in 167 aa overlap. Contains match to Prosite entry FT PS01162 Quinone oxidoreductase / zeta-crystallin signature" FT /note="SCBAC20F6.18, ORF4, possible oxidoreductase, len: FT 170 aa; identical to N-terminal region of the previously FT sequenced TR:Q53929 (EMBL:X62373) Streptomyces coelicolor FT ORF 4, 306 aa. Contains match to Prosite entry PS01162 FT Quinone oxidoreductase / zeta-crystallin signature" FT /db_xref="GOA:Q8CJS3" FT /db_xref="HSSP:1IZ0" FT /db_xref="InterPro:IPR013154" FT /db_xref="UniProtKB/TrEMBL:Q8CJS3" FT /protein_id="CAD55222.1" FT /translation="MPKAVAIHQFGGPDVLGLVDVPEPVPGPGQVTVRVRAAGVNGFDC FT RVRSGGMRGRYPVEFPQIIGNEFAGVVERTGPEATGFAPGDEVLGFAVLQSGTELLAVG FT ADQITVKPPELSWEVAGSLSAVGQTADIALAELRVGPGDTVLVHAAAGGVGSLAVQLVR FT ERGGTAIGSAGEHNHDYLRSLGALPVAYGPGFADRVRALAPNGVDAALDCHGGPEALAV FT SLELVADRARIATVANFRAAAQEGIVMPRVVRSAERLAALAALCAEGRLRPHVEAVLPF FT AKAAEAHHRLEQGHVRGKLVLVPDL" FT misc_feature 147394..147910 FT /note="previously sequenced DNA fragment. EMBL:X62373 FT S.coelicolor genes for hydroxyacyl-CoA dehydrogenase" FT misc_feature 147400..147465 FT /note="PS01162 Quinone oxidoreductase / zeta-crystallin FT signature" FT misc_feature 147876..153275 FT /note="previously sequenced DNA fragment. EMBL:X58833.1 FT S.coelicolor 6 actVA region genes of the actinorhodin FT biosynthetic gene cluster" FT CDS 147894..149495 FT /transl_table=11 FT /gene="SCO5076" FT /gene_synonym="actVA1" FT /gene_synonym="SCBAC28G1.02" FT /product="integral membrane protein" FT /note="SCBAC28G1.02, actVA1, probable integral membrane FT protein, len: 533 aa; identical to previously sequenced FT TR:Q53903 (EMBL:X58833) Streptomyces coelicolor 6 ActVA FT region genes of the actinorhodin biosynthetic gene cluster, FT ActVA1, 533 aa. Contains possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q53903" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q53903" FT /protein_id="CAC44189.1" FT /translation="MTANPGRPGGPADQGHPRRWAILGVLVLSLVGIILDNTVLNVTLR FT TLTDPEQGLGASHSQVEWVLSAYTLAFAATLFTWGVLGDRLGRRRVLLLGLGLFGLSSL FT AGAYAGSPEQLIAARACMGVSGAAVLPSTLATIAAVFPLRERPKALGIWAASVGFALGI FT GPVTGGILLAHFWWGSVLLVNVPLMAGCLVAVVLVVPETRGTAGRRVDAAGLLLSIAGV FT VPLVYAIIEAGRSGGVTRPAVWAAGLAGLGLLLVFLWHERRTPEPSLELGFFRMKAFST FT AVAAVGFVSFAMMGFLFFSAFYLQSVRGYTPLQAGGCTVALAVANVVCGPLSTVLVRSI FT GPRNVCAAGMLAVTASLCGVTFVTQHAPVWLILVLFAALGAGVACVMPTAAVSIMNAIP FT REKAGVASAMNNTVRQLGGALGVAVLGSLMGAAYRRGIEDELAVLPPSARHQAGESLDA FT TLLAATRLGESGLVGPARQAFLDAMHLAAGAAAAVALVGALAVLRWLPSSVTTPTPPAG FT AVPGREHSDHLKVQGS" FT RBS 149485..149489 FT CDS 149497..149892 FT /transl_table=11 FT /gene="SCO5077" FT /gene_synonym="actVA2" FT /gene_synonym="SCBAC28G1.03" FT /product="hypothetical protein" FT /note="SCBAC28G1.03, actVA2, hypothetical protein, len: 131 FT aa; identical to previously sequenced TR:Q53904 FT (EMBL:X58833) Streptomyces coelicolor 6 ActVA region genes FT of the actinorhodin biosynthetic gene cluster, ActVA2, 131 FT aa" FT /db_xref="GOA:Q93IZ3" FT /db_xref="InterPro:IPR011576" FT /db_xref="UniProtKB/TrEMBL:Q93IZ3" FT /protein_id="CAC44190.1" FT /translation="MPFTPDELEYYASQNLGRLATVAPDGQPQANPVSFRVNTETGTID FT IGGHNLTASKKFRNVTKHDQVAFVVDDLISTQPWNVRGIEVRGRAEALTDAQPPHPYFG FT TAMIRIHPKRIITWGLGGDAAQRGRDV" FT RBS 149974..149978 FT CDS 149987..150832 FT /transl_table=11 FT /gene="SCO5078" FT /gene_synonym="actVA3" FT /gene_synonym="SCBAC28G1.04" FT /product="hypothetical protein" FT /note="SCBAC28G1.04, actVA3, hypothetical protein, len: 281 FT aa; identical to previously sequenced TR:Q53905 FT (EMBL:X58833) Streptomyces coelicolor 6 ActVA region genes FT of the actinorhodin biosynthetic gene cluster, ActVA3, 281 FT aa" FT /db_xref="UniProtKB/TrEMBL:Q93IZ2" FT /protein_id="CAC44191.1" FT /translation="MSTEIFHEEFAGGLVTEGPGAPWRLRPVDGLEAGDGLVRGGPDGL FT VVVPSAAHPGTRRPAFTEPKPGPDGTPLHLRWGAFTTGGTTGGTAGARAAFTAVPGERL FT SVRAEMGLRGFGLRSHPYDDVTEPDADARLGAGGLISVDLESGIIFDFFLTHSRLYAVY FT ERLALRPDAEFAAFTYCVPVADRTPGTLHRLEVGYDVAAGTAHWTADGQEVLSVDRIGF FT RALDARWLRRDNGGREEAVRPRGLSFGLGLFLERHFGQGVRLSVRRLSVLTSPAGSRDS FT " FT RBS 150844..150849 FT CDS 150857..151741 FT /transl_table=11 FT /gene="SCO5079" FT /gene_synonym="actVA4" FT /gene_synonym="SCBAC28G1.05" FT /product="conserved hypothetical protein" FT /note="SCBAC28G1.05, actVA4, conserved hypothetical FT protein, len: 294 aa; identical to previously sequenced FT TR:Q53906 (EMBL:X58833) Streptomyces coelicolor 6 ActVA FT region genes of the actinorhodin biosynthetic gene cluster, FT ActVA4, 294 aa" FT /db_xref="GOA:Q53906" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q53906" FT /protein_id="CAC44192.1" FT /translation="MPDENKPVLVLGATGKQGGSAARYLLERGWTVRAFVRDPGAPKAK FT ELRELGASLHTGDLEDAGSVRAAMKGAYGVFSIQTPMTPAGVEGEERQGKICADAARDL FT GVQHYVHSSVGGAERPEGVNWRLSKLAIEQRIQENALRFTFLRPSYFMENLNHDMSPLV FT MEDGVLTFRRGLGPANTLQMISGPDIGYFAADAFDDPDTFGGAKIELAGDELTGEQIAA FT AFGRHTGLPARFVSVPIPELHRTGFEWQAISYTWLNGIGYHADIPTLRARFPQLLTLDQ FT WLARTGWTPRDPA" FT RBS 151726..151729 FT CDS 151738..152883 FT /transl_table=11 FT /gene="SCO5080" FT /gene_synonym="actVA5" FT /gene_synonym="SCBAC28G1.06" FT /product="putative hydrolase" FT /note="SCBAC28G1.06, actVA5, possible hydrolase, len: 381 FT aa; identical to previously sequenced TR:Q53907 FT (EMBL:X58833) Streptomyces coelicolor 6 ActVA region genes FT of the actinorhodin biosynthetic gene cluster, ActVA5, 381 FT aa and similar to TR:Q9F0J3 (EMBL:AF218066) Streptomyces FT arenae hydrolase NcnH, 405 aa; fasta scores: opt: 1391 FT Z-score: 1521.5 bits: 290.3 E(): 3.9e-77; 56.522% identity FT in 368 aa overlap" FT /db_xref="GOA:Q53907" FT /db_xref="InterPro:IPR013107" FT /db_xref="UniProtKB/TrEMBL:Q53907" FT /protein_id="CAC44193.1" FT /translation="MSEDTMTQERPSLTAHARRIAELAGKRAADAEQQRRLSPDVVDAV FT LRAGFAAHFVPVAHGGRAATFGELVEPVAVLGEACASTAWYASLTASLGRMAAYLPDEG FT QAELWSDGPDALIVGALMPLGRAEKTPGGWHVSGTWPFVSVVDHSDWALICAKVGEEPW FT FFAVPRQEYGIVDSWYPMGMRGTGSNTLVLDGVFVPDARACTRAAIAAGLGPDAEAICH FT TVPMRAVNGLAFALPMLGAARGAAAVWTSWTAGRLAGPTGQNAVSSQDRVVYEHTLARA FT TGEIDAAQLLLERVAAVADAGSATGVLVGRGARDCALAAELLTAATDRLFASAGTRAQA FT QDSPMQRLWRDVHAAGSHIGLQFGPGAALYAGELLRRSNDG" FT RBS 152863..152868 FT CDS 152876..153217 FT /transl_table=11 FT /gene="SCO5081" FT /gene_synonym="actVA6" FT /gene_synonym="SCBAC28G1.07" FT /product="hypothetical protein" FT /note="SCBAC28G1.07, actVA6, hypothetical protein, len: 113 FT aa; identical to previously sequenced TR:Q53908 FT (EMBL:X58833) Streptomyces coelicolor 6 ActVA region genes FT of the actinorhodin biosynthetic gene cluster, ActVA6, 113 FT aa and similar to SW:TCMH_STRGA (EMBL:M80674) Streptomyces FT glaucescens tetracenomycin polyketide synthesis hydroxylase FT TcmH, 112 aa; fasta scores: opt: 193 Z-score: 247.6 bits: FT 51.0 E(): 3.5e-06; 43.210% identity in 81 aa overlap" FT /db_xref="GOA:Q53908" FT /db_xref="InterPro:IPR007138" FT /db_xref="PDB:1LQ9" FT /db_xref="UniProtKB/TrEMBL:Q53908" FT /protein_id="CAC44194.1" FT /translation="MAEVNDPRVGFVAVVTFPVDGPATQHKLVELATGGVQEWIREVPG FT FLSATYHASTDGTAVVNYAQWESEQAYRVNFGADPRSAELREALSSLPGLMGPPKAVFM FT TPRGAILPS" FT misc_feature 152991..158890 FT /note="previously sequenced DNA fragment. EMBL:M64683 FT Streptomyces coelicolor ORF1-4 (actII) gene, complete cds" FT CDS complement(153183..153962) FT /transl_table=11 FT /gene="SCO5082" FT /gene_synonym="actII-1" FT /gene_synonym="SCBAC28G1.08c" FT /product="putative transcriptional regulatory protein" FT /note="SCBAC28G1.08c, actII-1, probable transcriptional FT regulatory protein, len: 259 aa; identical to previously FT sequenced TR:Q53901 (EMBL:M64683) Streptomyces coelicolor FT ORF1-4 (ActII), 259 aa. Contains Pfam matches to entries FT PF00440 tetR, Bacterial regulatory proteins, tetR family FT and PF02909 tetR_C, Tetracyclin repressor, C-terminal FT all-alpha domain and possible helix-turn-helix motif at FT residues 53..73 (+2.78 SD)" FT /db_xref="GOA:Q53901" FT /db_xref="InterPro:IPR012287" FT /db_xref="PDB:2OPT" FT /db_xref="UniProtKB/TrEMBL:Q53901" FT /protein_id="CAC44195.1" FT /translation="MSRSEEGRPMPEEIPVPPWRRPKKAPPRMPLTQDRIVVTALGILD FT AEGLDALSMRRLAQELKTGHASLYAHVGNRDELLDLVFDIVLTEVEVPEPEPGRWAEQV FT KEMCRSLRRMFLAHRDLARIAIDRVPLGPNGMVGMERTMNLLRSGGLHDELAAYGGDLL FT STFVTAEALEQSSRNPGTEQGREQAGVFADQLHGYLKSLPATSFPNLVHLAGPITSLDS FT DRRFELGLEIIIAGLLAGAGEAADDQVRTAGSPPAES" FT misc_feature complement(153240..153683) FT /note="Pfam match to entry PF02909 tetR_C, Tetracyclin FT repressor, C-terminal all-alpha domain, score 217.30, FT E-value 2.2e-61" FT misc_feature complement(153717..153857) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 43.50, E-value FT 1.3e-09" FT RBS complement(153968..153971) FT CDS 154073..155809 FT /transl_table=11 FT /gene="SCO5083" FT /gene_synonym="actII-2" FT /gene_synonym="SCBAC28G1.09" FT /product="putative actinorhodin transporter" FT /note="SCBAC28G1.09, actII-2, probable actinorhodin FT transporter, len: 578 aa; identical to previously sequenced FT SW:AC22_STRCO (EMBL:M64683) Streptomyces coelicolor FT probable actinorhodin transporter ActII-2, 578 aa. Contains FT possible hydrophobic membrane spanning regions and a FT leucine TTA codon, possible target for bldA regulation" FT /db_xref="GOA:P46105" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/Swiss-Prot:P46105" FT /protein_id="CAC44196.1" FT /translation="MSSVEADEPDRATAPPSALLPEDGPGPDGTAAGPPPYARRWAALG FT VILGAEIMDLLDGTVMNVAAPAVRADLGGSLSVIQWITVGYTLAFAVLLVVGGRLGDIY FT GRKRMFVVGAVGFTAASVLCSVAAGPEMLTAARFLQGGLGALMIPQGLGLIKQMFPPKE FT TAAAFGAFGPAIGLGAVLGPIVAGFLVDADLFGTGWRSVFLINLPIGVAVIVGAVLLLP FT EGKAPVRPKFDVVGMALVTSGLTLLIFPLVQGRERGWPAWAFVLMLAGAAVLVGFVAHE FT LRQERRGGATLIELSLLRRSRYAAGLAVALVFFTGVSGMSLLLALHLQIGLGFSPTRAA FT LTMTPWSVFLVVGAILTGAVLGSKFGRKALHGGLVVLALGVLIMLLTIGDQAGGLTSWE FT LVPGIAVAGLGMGIMIGLLFDIALADVDKQEAGTASGVLTAVQQLGFTVGVAVLGTLFF FT GLLGSQATASVDDGASRARTELAAAGASTTEQDRLLADLRVCLRESASQQDSERTPDSC FT RNLQQARPAVAEATARAWRTAHTENFSTAMVRTLWVVIALLAVSFALAFRLPPKPREEE FT GF" FT misc_feature 154127..154129 FT /note="TTA leucine codon; possible target for bldA FT regulation" FT CDS 155809..157944 FT /transl_table=11 FT /gene="SCO5084" FT /gene_synonym="actII-3" FT /gene_synonym="SCBAC28G1.10" FT /product="putative membrane protein" FT /note="SCBAC28G1.10, actII-3, putative membrane protein, FT len: 711 aa; identical to previously sequenced FT SW:MMLA_STRCO (EMBL:M64683) Streptomyces coelicolor FT putative membrane protein ActII-3, 711 aa. Contains FT possible hydrophobic membrane spanning regions" FT /db_xref="GOA:Q53902" FT /db_xref="InterPro:IPR000731" FT /db_xref="UniProtKB/Swiss-Prot:Q53902" FT /protein_id="CAC44197.1" FT /translation="MTRTLLSWPGGRRLKWLVLAAWIGLLIVLQPLAGKLGDVESNDAA FT AWLPGNAESTEVLELSEKFQPADTSPTVIVYDRPSGITAADEAKARADATHFADGTGVV FT GEPYGPVRSDDGKALRTVVNVHLGKDGWEGLNAAAKDMRAIARPSAPDGLGVHVTGPTG FT YAADSAESFSSADFKLTLVTLLIVVTILVVTYRSPLLWLLPMISAGMSLVISQAIVYLL FT AKNAGLTVNAQTAMILTVLVLGAATDYALLLVARYREELRRHEDRHEAMAVALRRAGPA FT IVASAATVAVSMLVLLLAALNSTKGLGPVCAVGVLVGLLSMMTLLPALLVIFGRWVFWP FT ARPKHGTEPDVTRGLWSRIARLVSGRPRAVWVTTSLLLGAVATLAVTLNADGLQQKDGF FT KTKPESVVGEEILTRHFPAGSGEPMVVIAKGASADQVHAALETVPGVIEVAPPQVKDGL FT AYVEATLGAGADSPAAMRSVTAARETLARLDGAQARVGGSSAVVHDMREASSRDRGLII FT PVILAVVFCILALLLRALVAPLLLIASVVLSFFTALGLAALFFNHVFDFAGADSAFPLW FT VFVFLVALGVDYNIFLVTRIKEESDRLGTRQGALKGLTSTGGVITAAGLVLAGTFAALA FT TLPLVFIAELGFTVAVGVLLDTMIVRSVLVTALTLDVGRWMWWPHPLARREDPSEDPAV FT SGMPDSIDSEASTTASR" FT stem_loop 157951..157993 FT /note="possible stem loop. Score 60: 20/20 (100%) matches, FT 0 gaps" FT misc_feature 157957..157962 FT /note="AseI site matched ATTAAT. Divides the AseI-K and the FT AseI-N genomic restriction fragments" FT /note="Cleavage site for AseI restriction endonuclease FT AT*TAAT." FT misc_feature complement(157957..157962) FT /note="Cleavage site for AseI restriction endonuclease FT AT*TAAT." FT misc_feature 157983..157988 FT /note="AseI site matched ATTAAT. Divides the AseI-K and the FT AseI-N genomic restriction fragments" FT /note="Cleavage site for AseI restriction endonuclease FT AT*TAAT." FT misc_feature complement(157983..157988) FT /note="Cleavage site for AseI restriction endonuclease FT AT*TAAT." FT CDS 158094..158861 FT /transl_table=11 FT /gene="SCO5085" FT /gene_synonym="actII-4" FT /gene_synonym="SCBAC28G1.11" FT /product="actinorhodin cluster activator protein" FT /note="SCBAC28G1.11, actII-4, actinorhodin cluster FT activator protein, len: 255 aa; identical to previously FT sequenced SW:AC24_STRCO (EMBL:M64683) Streptomyces FT coelicolor actinorhodin operon activator protein ActII-4, FT 255 aa. Contains a leucine TTA codon, possible target for FT bldA regulation" FT /db_xref="GOA:P46106" FT /db_xref="InterPro:IPR001867" FT /db_xref="UniProtKB/Swiss-Prot:P46106" FT /protein_id="CAC44198.1" FT /translation="MRFNLLGRVHVITDAGCVIPLKSSKATQLLVLLLLRRHEVVGSGV FT LIEELWADHPPRSAMTTLQTYVYHTRRLLGEHRVTSDDRELVLTQPPGYFALIDEDELD FT VAVAERLIRTGGRLLEENRLEEALASLDAGLDLWRGPALSTVPCGRVLESNIAHLEELR FT LFGMQLRIDANWRLGRIGPMIPELRSLVISHPLNETLHAKLMGALCQMGRRAEALESYR FT NLRRILSDELGVDPTPEIQRMHMEILNGEKVLV" FT misc_feature 158106..158108 FT /note="TTA leucine codon; possible target for bldA FT regulation" FT misc_feature complement(158795..159829) FT /note="previously sequenced DNA fragment. EMBL:M19536 FT S.coelicolor actIII gene, complete cds." FT stem_loop 158864..158928 FT /note="possible stem loop. Score 96: 32/32 (100%) matches, FT 0 gaps" FT CDS complement(158935..159720) FT /transl_table=11 FT /gene="SCO5086" FT /gene_synonym="actIII" FT /gene_synonym="SCBAC28G1.12c" FT /product="ketoacyl reductase" FT /note="SCBAC28G1.12c, actIII, ketoacyl reductase, len: 261 FT aa; identical to previously sequenced SW:ACT3_STRCO FT (EMBL:M19536) Streptomyces coelicolor putative ketoacyl FT reductase ActIII, 261 aa. Contains Pfam matches to entries FT PF00106 adh_short, short chain dehydrogenase and PF00678 FT adh_short_C2, Short chain dehydrogenase/reductase FT C-terminus and match to Prosite entry PS00061 Short-chain FT dehydrogenases/reductases family signature" FT /db_xref="GOA:P16544" FT /db_xref="InterPro:IPR016040" FT /db_xref="PDB:1W4Z" FT /db_xref="UniProtKB/Swiss-Prot:P16544" FT /protein_id="CAC44199.1" FT /translation="MATQDSEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRT FT TLKELREAGVEADGRTCDVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELAD FT ELWLDVVETNLTGVFRVTKQVLKAGGMLERGTGRIVNIASTGGKQGVVHAAPYSASKHG FT VVGFTKALGLELARTGITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVP FT IGRYVQPSEVAEMVAYLIGPGAAAVTAQALNVCGGLGNY" FT misc_feature complement(158959..159051) FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 25.80, FT E-value 1.4e-05" FT misc_feature complement(159142..159702) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 302.10, E-value 6.8e-87" FT misc_feature complement(159205..159291) FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT RBS 159792..159795 FT CDS 159801..161204 FT /transl_table=11 FT /gene="SCO5087" FT /gene_synonym="actIORF1" FT /gene_synonym="SCBAC28G1.13" FT /product="actinorhodin polyketide beta-ketoacyl synthase FT alpha subunit" FT /note="SCBAC28G1.13, actIORF1, actinorhodin polyketide FT beta-ketoacyl synthase alpha subunit, len: 467 aa; FT identical to C-terminal region of SW:KASA_STRCO FT (EMBL:X63449) Streptomyces coelicolor actinorhodin FT polyketide putative beta-ketoacyl synthase 1 ActI ORF1, 424 FT aa. Previously sequenced start codon at residue 44 of this FT sequence. Also similar to TR:CAB45606 (EMBL:AL079356) FT Streptomyces coelicolor polyketide beta-ketoacyl synthase FT alpha (WhiE locus) SC6G9.15, 424 aa; fasta scores: opt: FT 1706 Z-score: 1660.2 bits: 316.4 E(): 9.5e-87; 61.871% FT identity in 417 aa overlap. Contains Pfam matches to FT entries PF00109 ketoacyl-synt, Beta-ketoacyl synthase, FT N-terminal domain and PF02801 ketoacyl-synt_C, FT Beta-ketoacyl synthase, C-terminal domain and match to FT Prosite entry PS00606 Beta-ketoacyl synthases active site" FT /db_xref="GOA:Q02059" FT /db_xref="InterPro:IPR016038" FT /db_xref="PDB:1QXG" FT /db_xref="UniProtKB/Swiss-Prot:Q02059" FT /protein_id="CAC44200.1" FT /translation="MPLDAAPVDPASRGPVSAFEPPSSHGADDDDDHRTNASKELFGLK FT RRVVITGVGVRAPGGNGTRQFWELLTSGRTATRRISFFDPSPYRSQVAAEADFDPVAEG FT FGPRELDRMDRASQFAVACAREAFAASGLDPDTLDPARVGVSLGSAVAAATSLEREYLL FT LSDSGRDWEVDAAWLSRHMFDYLVPSVMPAEVAWAVGAEGPVTMVSTGCTSGLDSVGNA FT VRAIEEGSADVMFAGAADTPITPIVVACFDAIRATTARNDDPEHASRPFDGTRDGFVLA FT EGAAMFVLEDYDSALARGARIHAEISGYATRCNAYHMTGLKADGREMAETIRVALDESR FT TDATDIDYINAHGSGTRQNDRHETAAYKRALGEHARRTPVSSIKSMVGHSLGAIGSLEI FT AACVLALEHGVVPPTANLRTSDPECDLDYVPLEARERKLRSVLTVGSGFGGFQSAMVLR FT DAETAGAAA" FT misc_feature 159824..165109 FT /note="previously sequenced DNA fragment. EMBL:X63449 FT S.coelicolor genes actIORF1, actIORF2, actIORF3, actVII, FT actIV and actVB for beta-ketoacyl synthase/acyl FT transferase, acyl carrier protein, cyclase/dehydrase, FT dehydrase and dimerase" FT misc_feature 159933..160682 FT /note="Pfam match to entry PF00109 ketoacyl-synt, FT Beta-ketoacyl synthase, N-terminal domain, score 310.40, FT E-value 2.2e-89" FT misc_feature 160407..160457 FT /note="PS00606 Beta-ketoacyl synthases active site" FT misc_feature 160707..161183 FT /note="Pfam match to entry PF02801 ketoacyl-synt_C, FT Beta-ketoacyl synthase, C-terminal domain, score 248.10, FT E-value 1.2e-70" FT misc_feature 161201..161923 FT /note="Pfam match to entry PF00109 ketoacyl-synt, FT Beta-ketoacyl synthase, N-terminal domain, score 279.40, FT E-value 4.5e-80" FT CDS 161201..162424 FT /transl_table=11 FT /gene="SCO5088" FT /gene_synonym="actIORF2" FT /gene_synonym="SCBAC28G1.14" FT /product="actinorhodin polyketide beta-ketoacyl synthase FT beta subunit" FT /note="SCBAC28G1.14, actIORF2, actinorhodin polyketide FT beta-ketoacyl synthase beta subunit (also known as chain FT length factor), len: 407 aa; identical to previously FT sequenced SW:KASB_STRCO (EMBL:X63449) Streptomyces FT coelicolor actinorhodin polyketide putative beta-ketoacyl FT synthase 2 ActI ORF2, 407 aa. Contains Pfam matches to FT entries PF00109 ketoacyl-synt, Beta-ketoacyl synthase, FT N-terminal domain and PF02801 ketoacyl-synt_C, FT Beta-ketoacyl synthase, C-terminal domain" FT /db_xref="GOA:Q02062" FT /db_xref="InterPro:IPR016038" FT /db_xref="PDB:1QXG" FT /db_xref="UniProtKB/Swiss-Prot:Q02062" FT /protein_id="CAC44201.1" FT /translation="MSVLITGVGVVAPNGLGLAPYWSAVLDGRHGLGPVTRFDVSRYPA FT TLAGQIDDFHAPDHIPGRLLPQTDPSTRLALTAADWALQDAKADPESLTDYDMGVVTAN FT ACGGFDFTHREFRKLWSEGPKSVSVYESFAWFYAVNTGQISIRHGMRGPSSALVAEQAG FT GLDALGHARRTIRRGTPLVVSGGVDSALDPWGWVSQIASGRISTATDPDRAYLPFDERA FT AGYVPGEGGAILVLEDSAAAEARGRHDAYGELAGCASTFDPAPGSGRPAGLERAIRLAL FT NDAGTGPEDVDVVFADGAGVPELDAAEARAIGRVFGREGVPVTVPKTTTGRLYSGGGPL FT DVVTALMSLREGVIAPTAGVTSVPREYGIDLVLGEPRSTAPRTALVLARGRWGFNSAAV FT LRRFAPTP" FT misc_feature 161951..162412 FT /note="Pfam match to entry PF02801 ketoacyl-synt_C, FT Beta-ketoacyl synthase, C-terminal domain, score 188.60, FT E-value 1e-52" FT RBS 162439..162442 FT CDS 162449..162709 FT /transl_table=11 FT /gene="SCO5089" FT /gene_synonym="actIORF3" FT /gene_synonym="SCBAC28G1.15" FT /product="actinorhodin polyketide synthase acyl carrier FT protein" FT /note="SCBAC28G1.15, actIORF3, actinorhodin polyketide FT synthase acyl carrier protein, len: 86 aa; identical to FT previously sequenced SW:ACPA_STRCO (EMBL:X63449) FT Streptomyces coelicolor actinorhodin polyketide synthase FT acyl carrier protein ActI ORF3, 86 aa. Contains Pfam match FT to entry PF00550 pp-binding, Phosphopantetheine attachment FT site and match to Prosite entry PS00012 Phosphopantetheine FT attachment site" FT /db_xref="GOA:Q02054" FT /db_xref="InterPro:IPR006162" FT /db_xref="PDB:2AF8" FT /db_xref="UniProtKB/Swiss-Prot:Q02054" FT /protein_id="CAC44202.1" FT /translation="MATLLTTDDLRRALVECAGETDGTDLSGDFLDLRFEDIGYDSLAL FT METAARLESRYGVSIPDDVAGRVDTPRELLDLINGALAEAA" FT misc_feature 162482..162682 FT /note="Pfam match to entry PF00550 pp-binding, FT Phosphopantetheine attachment site, score 68.00, E-value FT 3.4e-17" FT misc_feature 162557..162604 FT /note="PS00012 Phosphopantetheine attachment site" FT RBS 162698..162701 FT CDS 162706..163656 FT /transl_table=11 FT /gene="SCO5090" FT /gene_synonym="actVII" FT /gene_synonym="SCBAC28G1.16" FT /product="actinorhodin polyketide synthase bifunctional FT cyclase/dehydratase" FT /note="SCBAC28G1.16, actVII, actinorhodin polyketide FT synthase bifunctional cyclase/dehydratase, len: 316 aa; FT identical to previously sequenced SW:CYPK_STRCO FT (EMBL:X63449) Streptomyces coelicolor actinorhodin FT polyketide synthase bifunctional cyclase/dehydratase ActI FT ORF4, 316 aa" FT /db_xref="GOA:Q02055" FT /db_xref="InterPro:IPR005031" FT /db_xref="UniProtKB/Swiss-Prot:Q02055" FT /protein_id="CAC44203.1" FT /translation="MSRPGEHRVVHTLRTQAPARRLYELVARVEDWPAVFEPTVHVQVL FT ERGPGTERFRIWARVGGRVKTWTSRRTLDPDTLRVTFRQELTQPPIASMGGSWEFRGDG FT DGTEVVLTHDFAAVDEAALPGLREALDANSGKELAALVALAERRQPPEELVFTFEDTLR FT VPSGDDAYAFIERSDLWQERLPHVRKVTLTEEAAGTGPAETRDMTVQDMTMETVTTDGG FT THTTRSIRLCVPARSIVYKQLVPPALLSGHCGAWTFGEDTVTARHTVAIDPARVEEVLG FT KGATVADARTHLREVLGANSRATLRHAAAAAGPAS" FT CDS 163653..164546 FT /transl_table=11 FT /gene="SCO5091" FT /gene_synonym="actIV" FT /gene_synonym="SCBAC28G1.17" FT /product="cyclase" FT /note="SCBAC28G1.17, actIV, cyclase, len: 297 aa; identical FT to previously sequenced TR:Q02057 (EMBL:X63449) FT Streptomyces coelicolor dehydrogenase ActI ORF5, 297 aa. FT Contains Pfam match to entry PF00753 lactamase_B, FT Metallo-beta-lactamase superfamily" FT /db_xref="GOA:Q93IZ0" FT /db_xref="InterPro:IPR001279" FT /db_xref="UniProtKB/TrEMBL:Q93IZ0" FT /protein_id="CAC44204.1" FT /translation="MTVEVREVAEGVYAYEQAPGGWCVSNAGIVVGGDGALVVDTLSTI FT PRARRLAEWVDKLAAGPGRTVVNTHFHGDHAFGNQVFAPGTRIIAHEDMRSAMVTTGLA FT LTGLWPRVDWGEIELRPPNVTFRDRLTLHVGERQVELICVGPAHTDHDVVVWLPEERVL FT FAGDVVMSGVTPFALFGSVAGTLAALDRLAELEPEVVVGGHGPVAGPEVIDANRDYLRW FT VQRLAADAVDRRLTPLQAARRADLGAFAGLLDAERLVANLHRAHEELLGGHVRDAMAIF FT AELVAYNGGQLPTCLA" FT misc_feature 163710..164264 FT /note="Pfam match to entry PF00753 lactamase_B, FT Metallo-beta-lactamase superfamily, score 124.60, E-value FT 1.9e-33" FT RBS 164547..164550 FT CDS 164558..165091 FT /transl_table=11 FT /gene="SCO5092" FT /gene_synonym="actVB" FT /gene_synonym="SCBAC28G1.18" FT /product="actinorhodin polyketide putative dimerase" FT /note="SCBAC28G1.18, actVB, actinorhodin polyketide FT possible dimerase, len: 177 aa; identical to previously FT sequenced SW:DIM6_STRCO (EMBL:X63449) Streptomyces FT coelicolor actinorhodin polyketide dimerase ActI ORF6, FT ActVB, 177 aa Contains Pfam match to entry PF01613 FT Flavin_Reduct, Flavin reductase like domain" FT /db_xref="GOA:Q02058" FT /db_xref="InterPro:IPR012349" FT /db_xref="UniProtKB/Swiss-Prot:Q02058" FT /protein_id="CAC44205.1" FT /translation="MAADQGMLRDAMARVPAGVALVTAHDRGGVPHGFTASSFVSVSME FT PPLALVCLARTANSFPVFDSCGEFAVSVLREDHTDLAMRFARKSADKFAGGEFVRTARG FT ATVLDGAVAVVECTVHERYPAGDHIILLGEVQSVHVEEKGVPAVYVDRRFAALCSAAGA FT CPSATGRGVPAHAG" FT misc_feature 164591..165031 FT /note="Pfam match to entry PF01613 Flavin_Reduct, Flavin FT reductase like domain, score 254.60, E-value 1.3e-72" FT misc_feature 165079..169930 FT /note="previously sequenced DNA fragment. EMBL:Y18817 FT Streptomyces coelicolor A3(2) transcriptional regulator and FT actinorhodin biosynthetic genes, strain J1501" FT CDS complement(165110..165607) FT /transl_table=11 FT /gene="SCO5093" FT /gene_synonym="ORF7" FT /gene_synonym="SCBAC28G1.19c" FT /product="putative mini-circle protein" FT /note="SCBAC28G1.19c, ORF7, putative mini-circle protein, FT len: 165 aa; identical to previously sequenced TR:Q9X9V2 FT (EMBL:Y18817) Streptomyces coelicolor A3(2) putative FT mini-circle protein ORF7, 165 aa" FT /db_xref="InterPro:IPR007061" FT /db_xref="UniProtKB/TrEMBL:Q7AKH4" FT /protein_id="CAC44206.1" FT /translation="MPTTPRTHRRDTPPPRTGGGEAETLRGFLDYLRTSIAGKVEDAPE FT PQVRTAAVASGTNLLGLLNHLTHVERAVFLGEEVRSWPATFRAASQDGVADVVARYREA FT VERANRVLDACTDLGAPLPRPRPGRPAPSVRWALTHMVEETGRHAGHADILRELIDGAT FT GR" FT RBS complement(165617..165621) FT CDS complement(165661..166287) FT /transl_table=11 FT /gene="SCO5094" FT /gene_synonym="ORF8" FT /gene_synonym="SCBAC28G1.20c" FT /product="putative methyltransferase" FT /note="SCBAC28G1.20c, ORF8, putative methyltransferase, FT len: 208 aa; identical to previously sequenced TR:Q9X9V1 FT (EMBL:Y18817) Streptomyces coelicolor A3(2) putative FT methyltransferase ORF8, 208 aa" FT /db_xref="GOA:Q7AKH3" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:Q7AKH3" FT /protein_id="CAC44207.1" FT /translation="MSTTDAVTFWDGVYAARPAPDAPRPNVRLVETVTGLPPGDALDLG FT CGSGGDALWLARRGWRVTAVDISGVAAERLAGHARTHGLGDLVDAVRHDLRDSFPEGRF FT DLVSAHYLHTPFDLDRASVLRGAAHALRPGGRLLVVDHGSTAPWSWDQDPDARHPAPQE FT VAADLALDPATWRVERAEAPRRTATGPGGRTAEVVDHVLLVRRAD" FT RBS complement(166293..166298) FT CDS 166422..166994 FT /transl_table=11 FT /gene="SCO5095" FT /gene_synonym="ORF9" FT /gene_synonym="SCBAC28G1.21" FT /product="putative DNA-binding protein" FT /note="SCBAC28G1.21, ORF9, probable DNA-binding protein, FT len: 190 aa; identical to previously sequenced as TR:Q9X9V0 FT (EMBL:Y18817) Streptomyces coelicolor A3(2) hypothetical FT 20.6 kDa protein ORF9, 190 aa and similar to TR:O86784 FT (EMBL:AL031317) Streptomyces coelicolor SC6G4.21, 202 aa; FT fasta scores: opt: 642 Z-score: 656.2 bits: 128.2 E(): FT 7.9e-31; 53.968% identity in 189 aa overlap. Contains Pfam FT match to entry PF01381 HTH_3, Helix-turn-helix and possible FT helix-turn-helix motif at residues 25..46 (+6.01 SD)" FT /db_xref="GOA:Q7AKH2" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q7AKH2" FT /protein_id="CAC44208.1" FT /translation="MDAATDDVLDAVGPRLRTLRRERGITLAHLSAATGVSESTLSRLE FT SGQRRATLELLLPLARIYDVPLDDLVGAPRTGDPRIHLKPVRRFGMVFVPLSRRPGGTQ FT AFKMIIPSRPAPLEPTPQTHEGSEWLYVLSGRLRLLVGERDLTLSPGEAAEFDTSLPHW FT LGSADGGAVELLVLFGLQGVRAHVHSG" FT misc_feature 166467..166631 FT /note="Pfam match to entry PF01381 HTH_3, Helix-turn-helix, FT score 59.50, E-value 7.3e-14" FT CDS complement(167246..168175) FT /transl_table=11 FT /gene="SCO5096" FT /gene_synonym="SCBAC28G1.22c" FT /product="LysR-family transcriptional regulatory protein" FT /note="SCBAC28G1.22c, LysR-family transcriptional FT regulatory protein, len: 309 aa; identical to previously FT sequenced TR:Q9X9U9 (EMBL:Y18817) Streptomyces coelicolor FT A3(2) transcriptional regulator of LysR family, 307 aa. FT Contains Pfam match to entry PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix protein, lysR family and match FT to Prosite entry PS00044 Bacterial regulatory proteins, FT lysR family signature. Also contains a possible FT helix-turn-helix motif at residues 22..43 (+5.22 SD)" FT /db_xref="GOA:Q93IY9" FT /db_xref="HSSP:1IXC" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q93IY9" FT /protein_id="CAC44209.1" FT /translation="MGMTTDVHVRELRYFATVAEELHFTRAAELLYVSQPALSKQIRAL FT ERQLGAELFHRGPRGVTLTEAGTALLPHARRMLADWTEGAAAVEAARAARRDTLVVGMS FT TSPGRGGLLPAIRSRFTAAHPEAVLQLRQMSWEDPTAGLADGTADVAYVWLPLPDADRY FT AWTVVAEEPRLVALPDSHPLAAREEIDFADLAGEPFLALPPEAGVLRDFWLALDERRAL FT DGPAARPPRVGAEISGTEETYEALVAGLGICLVATGNAPLITLGGVVTRPVRGLSPSRY FT ALARRREDEGRALVRGYVEACRRVTDRA" FT misc_feature complement(167720..168151) FT /note="Pfam match to entry PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix protein, lysR family, score FT 160.50, E-value 2.8e-44" FT misc_feature complement(168017..168109) FT /note="PS00044 Bacterial regulatory proteins, lysR family FT signature" FT RBS 168261..168264 FT CDS 168270..169100 FT /transl_table=11 FT /gene="SCO5097" FT /gene_synonym="SCBAC28G1.23" FT /product="short-chain oxidoreductase" FT /note="SCBAC28G1.23, short-chain oxidoreductase, len: 276 FT aa; identical to previously sequenced TR:Q9X9U8 FT (EMBL:Y18817) Streptomyces coelicolor A3(2) oxidoreductase FT of short-chain, 276 aa. Contains Pfam match to entry FT PF00106 adh_short, short chain dehydrogenase and match to FT Prosite entry PS00061 Short-chain dehydrogenases/reductases FT family signature" FT /db_xref="GOA:Q93IY8" FT /db_xref="HSSP:1FDU" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q93IY8" FT /protein_id="CAC44210.1" FT /translation="MNKVWLITGASSGFGRAIAEAALADGDVVVGAARRPEALDDLVAA FT HPDQMEALRLDVADTAAAGDAVRDVVARHGRVDVLVNNAGRTHVGALEETGEDELRALF FT DVHVFGPAALTRAVLPSMRERRSGAIVQMSSMGGQMSFAGFSAYSGTKFALEGMSEGLA FT DEVRDFGIKVLIVEPGSFRTGLFEAGNAGISADSGVYAKVGETRGMIAAGDGSQPGDPA FT RAAAVIRAALAAEHTPLRLPLGDDGVTAVLGHLDRVREEVETWEKQTRATAFDD" FT misc_feature 168276..168821 FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 211.20, E-value 1.6e-59" FT misc_feature 168672..168758 FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT CDS 169158..169622 FT /transl_table=11 FT /gene="SCO5098" FT /gene_synonym="ORF12" FT /gene_synonym="SCBAC28G1.24" FT /product="putative integral membrane protein" FT /note="SCBAC28G1.24, possible integral membrane protein, FT len: 154 aa; identical in its C-terminal domain to FT TR:Q9X9U7 (EMBL:Y18817) Streptomyces coelicolor A3(2) FT hypothetical 11.9 kDa protein ORF11, 113 aa. Contains FT possible hydrophobic membrane spanning regions and 10x FT degenerate repeat at N-terminal region: M(P/V). Alternative FT start codon in previously sequence EMBL entrance after the FT repeat region at residue 42" FT /db_xref="UniProtKB/TrEMBL:Q93IY7" FT /protein_id="CAC44211.1" FT /translation="MPDCTRPCPIVPVPMPMPMPMPMPMPMPVPVPASVPNQESAVLSS FT LKAVNLLVMFLLELAVYTAVVLWGVAVGGTWPVEVALGVGAPVVMMAAWALFGSPRARR FT PARGAGRFVLEVLWFGAGAAALAASGRPWWAAALAGVCLVNAVLRRLWKQ" FT repeat_region 169191..169250 FT /note="10x degenerate repeat translated in SCBAC28G1.24" FT CDS 169732..170862 FT /transl_table=11 FT /gene="SCO5099" FT /gene_synonym="SCBAC28G1.25" FT /product="putative membrane protein" FT /note="SCBAC28G1.25, possible membrane protein, len: 376 FT aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q93IY6" FT /protein_id="CAC44212.1" FT /translation="MSIPPPPGPQGQYPQGPYAPQWGHPLAPYPRPAPVSGLAVAAFVL FT GVLCFLPAVGLVLGLVALARIRRRGERGKGFAVAGCVLSSVGLALWTLTLSTGAAGDFW FT DGFRDAARGGGTAYSLEKGQCFTTPSGSLQGVTYDVDEVPCAREHDGEVFASFDLPDGS FT YPGDGEITRAADDRCYALQDAYAMDRWALPTDVDVYYLTPTAASWRTGDREITCLFGNT FT DERGTLTGSLRNDGARFDADQHTYLLAEGYLNRAMDEVPAAEAVEDDLAGYRTWAGQVS FT EALRGEVAMLDGHEWPAGAERPVAALTDDLRSAQEEWGLAAKAADLDAYYEHYGKGYDL FT VVADSTVTARKALGLATTPPDYEGGEGGGDDPGVEV" FT RBS 171000..171003 FT CDS 171010..171762 FT /transl_table=11 FT /gene="SCO5100" FT /gene_synonym="SCBAC28G1.26" FT /product="putative gntR-family regulatory protein" FT /note="SCBAC28G1.26, possible gntR-family regulatory FT protein, len: 250 aa; low similarity to SW:FARR_ECOLI FT (EMBL:X15790) Escherichia coli fatty acid responsive FT regulator (P30 protein) FarR, 240 aa; fasta scores: opt: FT 206 Z-score: 237.6 bits: 51.4 E(): 1.3e-05; 25.926% FT identity in 243 aa overlap. Contains Pfam match to entry FT PF00392 gntR, Bacterial regulatory proteins, gntR family" FT /db_xref="GOA:Q93IY5" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q93IY5" FT /protein_id="CAC44213.1" FT /translation="MTFGEQPAYLRVAGDLRKKIADGLLPPHTRLPSQARIREEYGVSD FT TVALEARKVLMAEGLVEGRSGSGTYVRERPVPRRVARSGYRPAGGATPFRQEQADGDAR FT GTWESRSEQAEASGAVAERLGIKPGDRVMCTRYVFREAGEAVMLSTSWEPLDLTGRTPV FT MLPEEGPLGGMGVVERMAAIDVVVDNVTEEVGARPGLAEELLALGGVPGHVVLVVQRTF FT YASGRAVETADVVVPADRYRVAYHLPVR" FT misc_feature 171043..171222 FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 50.40, E-value FT 5.3e-14" FT RBS 172197..172201 FT CDS 172208..172399 FT /transl_table=11 FT /gene="SCO5101" FT /gene_synonym="SCBAC28G1.27" FT /product="conserved hypothetical protein" FT /note="SCBAC28G1.27, conserved hypothetical protein, len: FT 63 aa; similar to TR:Q9HTF6 (EMBL:AE004953) Pseudomonas FT aeruginosa hypothetical protein PA5408, 58 aa; fasta FT scores: opt: 146 Z-score: 225.2 bits: 45.1 E(): 6.2e-05; FT 45.652% identity in 46 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q93IY4" FT /protein_id="CAC44214.1" FT /translation="MNDSTVTLPWLVFRQDDNGNRYRVGRYATRAEAQEIADTLDGRGH FT KQLYWVEKLAAPGAGAAD" FT CDS 172475..172909 FT /transl_table=11 FT /gene="SCO5102" FT /gene_synonym="SCBAC28G1.28" FT /product="putative mutT-like protein" FT /note="SCBAC28G1.28, possible mutT-like protein, len: 144 FT aa; similar to SW:MUTT_ECOLI (EMBL:X04831) Escherichia coli FT mutator MutT protein FT (7,8-dihydro-8-oxoguanine-triphosphatase) (EC 3.6.1.*) FT MutT, 129 aa; fasta scores: opt: 190 Z-score: 228.6 bits: FT 48.1 E(): 4e-05; 33.333% identity in 132 aa overlap. FT Contains Pfam match to entry PF00293 mutT, MutT-like domain FT and match to Prosite entry PS00893 mutT domain signature" FT /db_xref="GOA:Q93IY3" FT /db_xref="HSSP:1JKN" FT /db_xref="InterPro:IPR020084" FT /db_xref="UniProtKB/TrEMBL:Q93IY3" FT /protein_id="CAC44215.1" FT /translation="MTERIVVGAALLDGGRLLAARRSAPAELAGRWELPGGKVEPGETP FT EAALVRELREELGVAAEAGGRVPGQWPLRAPFVLQVWTARLRPGSAAPAPLEDHDELRW FT LTPGQIWDVPWLDQDVPAVERVLAHLGLEAGTGRNGTGPG" FT misc_feature 172481..172861 FT /note="Pfam match to entry PF00293 mutT, MutT-like domain, FT score 85.50, E-value 1.1e-21" FT misc_feature 172583..172642 FT /note="PS00893 mutT domain signature" FT CDS 172948..173415 FT /transl_table=11 FT /gene="SCO5103" FT /gene_synonym="SCBAC28G1.29" FT /product="putative regulatory protein" FT /note="SCBAC28G1.29, possible regulatory protein, len: 155 FT aa; similar to TR:Q53897 (EMBL:X60316) Streptomyces FT coelicolor AbaA gene (putative regulator) or SCF42.12c, 192 FT aa; fasta scores: opt: 207 Z-score: 233.7 bits: 49.7 E(): FT 2.1e-05; 41.270% identity in 126 aa overlap. Contains Pfam FT match to entry PF02518 HATPase_c, Histidine kinase-, DNA FT gyrase B-, phytochrome-like ATPase" FT /db_xref="GOA:Q93IY2" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q93IY2" FT /protein_id="CAC44216.1" FT /translation="MGSSAGEVIGVKDGEGDCAEWVFPAAPDAVRTARSLVRRTLGEWR FT LDSVGDIAALLVSELVTNALRHATGPIGVRLVRSPAPAAPAAGGAGGDGADGVLLVEVS FT DPLPDPPRERVARPDDEDGRGLQLVASAARRWGTRPGEAGKTVWFELALPR" FT misc_feature 173095..173262 FT /note="Pfam match to entry PF02518 HATPase_c, Histidine FT kinase-, DNA gyrase B-, phytochrome-like ATPase, score FT 10.00, E-value 0.22" FT RBS 173699..173703 FT CDS 173715..176357 FT /transl_table=11 FT /gene="SCO5104" FT /gene_synonym="SCBAC28G1.30" FT /product="conserved hypothetical protein" FT /note="SCBAC28G1.30, hypothetical protein, len: 880 aa; FT similar to many Streptomyces coelicolor hypothetical FT proteins, e.g. TR:Q9KYN1 (EMBL:AL356592) hypothetical 84.7 FT kDa protein SC9H11.08, 802 aa; fasta scores: opt: 1062 FT Z-score: 1155.9 bits: 224.9 E(): 9.1e-57; 38.902% identity FT in 856 aa overlap. Contains 2x Pfam matches, Pfam match to FT entry PF01590 GAF, GAF domain, to entry PF00989 PAS, PAS FT domain and to entry PF02518 HATPase_c, Histidine kinase-, FT DNA gyrase B-, phytochrome-like ATPase" FT /db_xref="GOA:Q93IY1" FT /db_xref="InterPro:IPR010822" FT /db_xref="UniProtKB/TrEMBL:Q93IY1" FT /protein_id="CAC44217.1" FT /translation="MSEIPARAKEPTESTESGGPSADAPLGDAVWQSSPPGSIYDYIKV FT ASFSIGPDGLVDQWSLRAEQLLGIRAEDAVGSDPIEAFIDPDLRERGQRKMTEILDGRE FT WTGVVPFRAPDEAEGTARHASGRPADGPPTGGRPGQRGLAEVYVMPTRTEDGEKAAVCI FT VVDVRVLRSIETDLAASQAIFGQSPFGFLLIDPDLTVRRANQRFASIFGGTPDDHRGKG FT VHDYLPRAEADRVCATLRRVLETGDSITDMHVTGFVPGSEERRHWSVNLYRVHSGSGRP FT IGVAWLGTDITARRQAAREAANARRNLALLNEAGARIGNSLDLETTARELLDVVVPGFC FT DLATVDLYQGLLVGDETPPGLADGSAELRRVAFSSAVSDAPFLGTGERVKLGAVHHYPF FT NSPCADALRTARPRSVPAEDGGLVQSTLAVPMVAHDTVVGLVQFARTKGSEPFGDRDRD FT LAVELAARAAVCIDNARLYRREHERALILQRSLLPPGDPEASGLDIACRYLPGEAATGR FT ASEVGGDWFDVIELPGHRTALVVGDVMGRGLRAAVAMGELRTAVRTLAQLDIEPAEVLS FT QLDEIARGLGAPGGVQQATRAARRPREADLSEVYLATCVYAVYDSVTRRCTFANAGHLP FT PVLVEPGESALMLDVPPGLPLGVGGEPFEEVEVELPEGALLALYTDGLVESRDHPLDEG FT LQAFVGALTDPTQPLEDVCDQVLNTLDSHHGEDDIALLMARVQGLPADSVGDWTLPREP FT RSVGRAREYARAQLLAWDMEPLVDTTELLVSELVTNALRYGEGEIRLRLLLDRTLVCEV FT WDSGLVQPRRRRARDTDEGGRGLQLVGLLSAAWGSRRTPRGKTVWFELPLPGADTQLTD FT PAEALLSLF" FT misc_feature 173841..174011 FT /note="Pfam match to entry PF00989 PAS, PAS domain, score FT 9.80, E-value 0.44" FT misc_feature 174246..174440 FT /note="Pfam match to entry PF00989 PAS, PAS domain, score FT 15.70, E-value 0.0098" FT misc_feature 174681..175142 FT /note="Pfam match to entry PF01590 GAF, GAF domain, score FT 42.60, E-value 8.6e-09" FT misc_feature 176058..176162 FT /note="Pfam match to entry PF02518 HATPase_c, Histidine FT kinase-, DNA gyrase B-, phytochrome-like ATPase, score FT 9.60, E-value 0.28" FT RBS 176587..176591 FT CDS 176599..177831 FT /transl_table=11 FT /gene="SCO5105" FT /gene_synonym="SCBAC31E11.01" FT /product="putative membrane protein" FT /note="SCBAC31E11.01, possible membrane protein, len: 410 FT aa. Contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q93IV0" FT /protein_id="CAC44312.1" FT /translation="MADTEPGNTEPRSTEPGNTELRSTEPGSIEPGSTEPEAADGEDGP FT PGPPASDDESGTGGAGGNRDAEGEAEATRRTRRRTRIRRTAVAVLLVLLVPLLTAETAL FT RVNYMGDPADGTHTRNRDAMWLGHAWVDGRKDDADLAAFARRVKATGIRDLYVHTGPME FT HDGTLPKSLYPRARWLVGAVHRELPGVRVQAFLGDVLATESPDGMRLEKPATRAAVVGS FT ARQVLDVGYDGVHLDLEPLHSGDGDYLSLLDDVRAVTRARDAQLSVAAHQIDPLPGFHS FT FWGTVAGHPKWWSQEFFGQVARRVDQIAVMSYDTMQPLESLYGGYVAQQTSLALEVTPP FT TTHLLMGLPFYHENRFGHWNHAETVAAAVRGVRLGLSRTDADRERFGVAAYIDFAATEQ FT DWASYRDGWVR" FT CDS complement(177828..178607) FT /transl_table=11 FT /gene="SCO5106" FT /gene_synonym="SCBAC31E11.02c" FT /gene_synonym="shdB2" FT /product="putative succinate dehydrogenase iron-sulfur FT subunit" FT /note="SCBAC31E11.02c, shdB2, probable succinate FT dehydrogenase iron-sulfur subunit, len: 259 aa; highly FT similar to TR:AAK44479 (EMBL:AE006934) Mycobacterium FT tuberculosis ferredoxin, 2Fe-2S MT0261, 248 aa; fasta FT scores: opt: 1355 Z-score: 1588.1 bits: 301.4 E(): 7.7e-81; FT 74.900% identity in 251 aa overlap and to SW:DHSB_BACSU FT (EMBL:M13470) Bacillus subtilis succinate dehydrogenase FT iron-sulfur protein SdhB, 252 aa; fasta scores: opt: 365 FT Z-score: 434.1 bits: 87.9 E(): 1.4e-16; 30.603% identity in FT 232 aa overlap. Contains Pfam match to entry PF00111 fer2, FT 2Fe-2S iron-sulfur cluster binding domains" FT /db_xref="GOA:Q93IU9" FT /db_xref="InterPro:IPR004489" FT /db_xref="UniProtKB/TrEMBL:Q93IU9" FT /protein_id="CAC44313.1" FT /translation="MSGYEARFKVWRGDVAGGGLEDFTVEVNDGEVVLDIIHRLQATQA FT PDLAVRWNCKAGKCGSCSAEINGRPRLLCMTRMSVFTREETITVTPLRAFPVIRDLVTD FT VGFNYTKAREVPAFVPPADLGPGEYRMMQEDVDRSQEFRKCIECFLCQDTCHVVRDHEE FT NKPAFAGPRFLMRVAELDMHPLDAAGDTGLDRSRTAQDEHGLGFCNITKCCTEVCPEGI FT RITDNALIPLKERAVDRKYDPLVWLGAKIGRRSRDTP" FT misc_feature complement(178368..178550) FT /note="Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur FT cluster binding domains, score 35.00, E-value 1.7e-06" FT CDS complement(178604..180565) FT /transl_table=11 FT /gene="SCO5107" FT /gene_synonym="SCBAC31E11.02c" FT /gene_synonym="shdA2" FT /product="putative succinate dehydrogenase flavoprotein FT subunit" FT /note="SCBAC31E11.03c, shdA2, probable succinate FT dehydrogenase flavoprotein subunit, len: 653 aa; highly FT similar to TR:AAK44480 (EMBL:AE006934) Mycobacterium FT tuberculosis CDC1551 FAD flavoprotein oxidase, putative FT MT0262, 646 aa; fasta scores: opt: 2941 Z-score: 3164.4 FT bits: 595.8 E(): 1.2e-168; 70.416% identity in 649 aa FT overlap and to SW:DHSA_RICPR (EMBL:M88696) Rickettsia FT prowazekii succinate dehydrogenase flavoprotein subunit (EC FT 1.3.99.1) SdhA, 596 aa; fasta scores: opt: 643 Z-score: FT 693.1 bits: 138.4 E(): 5.4e-31; 35.218% identity; in 619 aa FT overlap. Contains Pfam matches to entries PF00890 FT FAD_binding_2, FAD binding domain and PF02910 FT succ_DH_flav_C, Fumarate reductase/succinate dehydrogenase FT flavoprotein C-terminal domain and match to Prosite entry FT PS00017 ATP/GTP-binding site motif A (P-loop" FT /db_xref="GOA:Q93IU8" FT /db_xref="HSSP:1D4D" FT /db_xref="InterPro:IPR004112" FT /db_xref="UniProtKB/TrEMBL:Q93IU8" FT /protein_id="CAC44314.1" FT /translation="MSVVDRQEWDVVVVGAGGAGLRAAVEARERGARTAVICKSLFGKA FT HTVMAEGGIAASMGNVNSGDNWQVHFRDTMRGGKFLNQWRMAELHAQEAPQRVWELETW FT GALFDRTKDGRISQRNFGGHEYPRLAHVGDRTGLELIRTLQQKIVSLQQEDFRETGDHE FT SRLKVFQECTVTRLLQEDRKVSGVFGYERESGRFFVLQAPSVVIATGGIGKSFKVTSNS FT WEYTGDGHALALLAGAPLLNMEFVQFHPTGMVWPPSVKGILVTESVRGDGGVLRNSEGR FT RFMFDYVPDVFKEKYAESEAEGDRWYDDPDHNRRPPELLPRDEVARAINAEVKEGRGSP FT HGGVFLDVSTRMPAEVIRRRLPSMYHQFKELADVDITAEAMEVGPTCHYVMGGIAVDSD FT TAAARGVPGLFAAGEVAGGMHGSNRLGGNSLSDLLVFGRRAGRYAAEYAAGRTEEGTRA FT RVDDAQVDAAAAEALRPFSAEAQEPGAGPPENPYTLHQELQQTMNDLVGIIRREAEMKQ FT ALEKLAELRVRARRAGVEGHRQFNPGWHLALDLRNMLLVSECVARAALERTESRGGHTR FT EDHPSMDRRWRPANLLCSLADPAGEAAGEAAATDPERGRIALERQTTEPIRPDLLALFD FT KEELVKYLADEELEGRSE" FT RBS complement(178618..178622) FT misc_feature complement(178769..179083) FT /note="Pfam match to entry PF02910 succ_DH_flav_C, Fumarate FT reductase/succinate dehydrogenase flavoprotein C-terminal FT domain, score 69.20, E-value 8.9e-17" FT misc_feature complement(179162..180238) FT /note="Pfam match to entry PF00890 FAD_binding_2, FAD FT binding domain, score 404.30, E-value 1.2e-117" FT misc_feature complement(179921..179944) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(180573..180576) FT CDS complement(180582..181418) FT /transl_table=11 FT /gene="SCO5108" FT /gene_synonym="SCBAC31E11.04c" FT /product="putative integral membrane protein" FT /note="SCBAC31E11.04c, possible integral membrane protein, FT len: 278 aa; similar to TR:O53671 (EMBL:AL021929) FT Mycobacterium tuberculosis hypothetical 31.1 kDa protein FT MTV034.15c, 273 aa; fasta scores: opt: 1010 Z-score: 1230.3 FT bits: 235.4 E(): 6.5e-61; 54.545% identity in 275 aa FT overlap. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="InterPro:IPR002345" FT /db_xref="UniProtKB/TrEMBL:Q93IU7" FT /protein_id="CAC44315.1" FT /translation="MATGTEPPATEDRPPGGGVHTPTRAAIRARHLRTDRWWLAPAATA FT AGLLAFVVYSTWRAFANADYYAAPYVSPFYSPCLAENCEPMRSGPNWELFGTWWGISPA FT IIILIFPLGFRLTCYYYRKAYYRGFWASPPACAVAEPHRKYTGETRFPLILQNVHRYFF FT YAALLVAGILSYDTVLAFRDEHYAWGHMGLGTLVFLANIALIWAYTLSCHSCRHIVGGK FT LKHFSRHPVRYRMWQLVGRLNARHMQLAWASLVSVALADFYVYLVASGVFDDPRFF" FT RBS complement(181426..181429) FT CDS complement(181480..181920) FT /transl_table=11 FT /gene="SCO5109" FT /gene_synonym="SCBAC31E11.05c" FT /product="hypothetical protein SCBAC31E11.05c" FT /note="SCBAC31E11.05c, unknown, len: 146 aa. Contains a FT possible coiled-coil region at approx. residues 60..87" FT /db_xref="UniProtKB/TrEMBL:Q93IU6" FT /protein_id="CAC44316.1" FT /translation="MPPAVHRRAPANRCTSLPSDWCDARHSQAHERSPPRPAAHCRVRR FT KRGHVLSVHDDLSSVQRSLDELSRTVTRLEQQLGSGDLEVRRVRTDADHLRESVALLRA FT ATAAPQAPRRPDLVPIPDTPYDGSLWTDSDDEGLGARDRRAP" FT RBS 182080..182085 FT CDS 182093..184408 FT /transl_table=11 FT /gene="SCO5110" FT /gene_synonym="SCBAC31E11.06" FT /product="putative lipoprotein" FT /note="SCBAC31E11.06, possible lipoprotein, len: 771 aa; FT similar to SW:YC80_MYCTU (EMBL:Z77137) Mycobacterium FT tuberculosis hypothetical 63.5 kDa protein MTCY50.02, 591 FT aa; fasta scores: opt: 565 Z-score: 501.6 bits: 103.2 E(): FT 2.5e-20; 26.190% identity in 756 aa overlap. Contains FT correctly situated match to Prosite entry PS00013 FT Prokaryotic membrane lipoprotein lipid attachment site and FT possible N-terminal region signal peptide sequence" FT /db_xref="GOA:Q93IU5" FT /db_xref="InterPro:IPR000914" FT /db_xref="UniProtKB/TrEMBL:Q93IU5" FT /protein_id="CAC44317.1" FT /translation="MSHVGVGPRAVMRAVAFLTTGVLAVPALAGCTSEDPAGKPLAEQD FT VAAAARARISDGGTLRWAVDSVPDTLNAFQSDADATTTRVAQAVLPSMYRMDETGSPVR FT NPDYLESAEVVDTEPKQVVVYKLNQQAVWSDGREIGAADFAAQWRALSGKDSAYWTARN FT AGYDRIEKVERGANDLEVKVTFSRPYADWKALFTPLYPKDVTGTPDAFNDGARRALKVS FT AGPFAVKKVDTKGDQVVLTGNPRWWGEPAKLDEIVLRAVPRDERVSELVAGKLDLAEID FT PETADEVTLAAGPRDPATGTPLMGPGGTPAAGPQGRSAAEALRSWAIANGSDEEAAEEE FT VLAREERGEAEAKARRRQQALSGFELRKSLEPAYTQLALNGAEGPLADERVRRAVARAL FT DREELAEAVLKPLGLPAEPVGSHLALSGQPAYADGSGALGEQNAKEARALLADAGWVPG FT GPVKKKDGEEAAGAEKDENKDEDKKDEEKSEGGDDGTYIVGEDDKNKDGKNKDGKNDDG FT KNDDGGNDDGGNDDAGDAKDGADRESGEKHSSGKNTAQGGAPGAYAPKGTAAPAGAAAA FT PLAKDGKELTLRFVLPSGPGSGTLRTVADRITDMLKEIGIGTRITKVPDESYFKDHIAA FT GEYDLALYSWPASAFPATDARPIYAKPVPAADGSLNVAQNYTRVGTDQVDQLFDRALAT FT LDQKESRDLLRKADSRIWAAAGSVPLYQRPQLTAARKNLANAGAFGFGTPVYEDMGFLK FT KGAQGSRPTAPASPSPSS" FT misc_feature 182153..182185 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature 183476..183553 FT /note="high content in lysine, glutamic acid and aspartic FT acid amino acid residues" FT misc_feature 183593..183712 FT /note="high content in aspartic acid, asparagine, glycine FT and lysine amino acid residues" FT RBS 184527..184530 FT CDS 184541..186448 FT /transl_table=11 FT /gene="SCO5111" FT /gene_synonym="SCBAC31E11.07" FT /product="putative GTP-binding protein" FT /note="SCBAC31E11.07, possible GTP-binding protein, len: FT 635 aa; similar to SW:TYPA_ECOLI (EMBL:L19201) Escherichia FT coli GTP-binding protein TypA/BipA (tyrosine phosphorylated FT protein A) TypA or BipA or B3871, 591 aa; fasta scores: FT opt: 915 Z-score: 968.6 bits: 189.3 E(): 2.5e-46; 48.039% FT identity in 612 aa overlap. Contains Pfam match to entry FT PF00009 GTP_EFTU, Elongation factor Tu family and matches FT to Prosite entries PS00017 ATP/GTP-binding site motif A FT (P-loop) and PS00301 GTP-binding elongation factors FT signature" FT /db_xref="GOA:Q93IU4" FT /db_xref="HSSP:1FNM" FT /db_xref="InterPro:IPR006298" FT /db_xref="UniProtKB/TrEMBL:Q93IU4" FT /protein_id="CAC44318.1" FT /translation="MATRHDIRNVAIVAHVDHGKTTIVDGMLKQAGAFAAHQLEGVDDR FT MMDSNDLEREKGITILAKNTAVKYHPKDGGDVITINIIDTPGHADFGGEVERGLSMVDG FT VVLLVDASEGPLPQTRFVLRKALSQRLPIILCINKTDRPDARIDEVVNETYDLFLDLDA FT DEEQIEFPIVYACGRDGVASLTKPEDGTVPSDSTSLEPFFSTILDHIPAPTYDEDAPLQ FT AHVTNLDADNFLGRIALLRVHQGELKKGQTVAWMKRDGSVQNVRISELMMTEALTRKPA FT EKAGPGDICAVAGIPDIMIGETLADVENPVPLPLITVDEPAISMTIGTNTSPLVGRGAT FT GKGADNKAVVKDRKVTARQVKDRLDRELIGNVSLRVLDTERPDAWEVQGRGELALAILV FT EQMRREGFELTIGKPQVVTKEVEGKTYEPVERMTIDVPEEHMGAVTQLMGVRKGRMDNM FT SNHGSGWVRMEFVVPSRGLIGFRTEFLTQTRGTGIAHSIHEGHEPWFGTLTTRNNGSLV FT ADRSGAVTAFAMTNLQERGVLFTDPGTEVYEGMIVGENSRADDMDVNITKEKKLTNMRS FT SSADSFEAIVPPRKLSLEQSLEFCRDDECVEVTPEAVRIRKVNLDARERARAASRAKHG FT " FT misc_feature 184553..185803 FT /note="Pfam match to entry PF00009 GTP_EFTU, Elongation FT factor Tu family, score 320.10, E-value 2.7e-92" FT misc_feature 184580..184603 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 184682..184729 FT /note="PS00301 GTP-binding elongation factors signature" FT stem_loop 186457..186513 FT /note="possible stem loop. Score 64: 24/26 (92%) matches, 0 FT gaps" FT misc_feature 186929..193308 FT /note="previously sequenced DNA fragment. EMBL:U68036 FT Streptomyces coelicolor bldKA, bldKB, bldKC, and bldkD FT genes, complete cds, and bldkE gene, partial cds" FT CDS 187355..188386 FT /transl_table=11 FT /gene="SCO5112" FT /gene_synonym="bldKA" FT /gene_synonym="SCBAC31E11.08" FT /product="BldKA, putative ABC transport system integral FT membrane protein" FT /note="SCBAC31E11.08, bldKA, possible ABC transport system FT integral membrane protein, len: 343 aa; identical to FT previously sequenced TR:P72406 (EMBL:U68036) Streptomyces FT coelicolor BldKA, 335 aa. Methionine start codon 9 amino FT acids upstream from the previous sequence start; possible FT frameshift from frame 2 into frame 1 in the previously FT sequenced DNA. Contains Pfam match to entry PF00528 FT BPD_transp, Binding-protein-dependent transport systems FT inner membrane component and match to Prosite entry PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign. Also contains possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q93IU3" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q93IU3" FT /protein_id="CAC44319.1" FT /translation="MTSPIEIEGAEASSVLDKESAPQGDAPKPKEPEGRKPGQLMWARF FT KRDRAGVISAFVVLFFFVIAAAAPLISMVYGKDPYTLYGQDNPDLLDMFTMPAAPYGGI FT DGDFWFGIEPGLGRDVFTQLLYGMRNSMATALAATIIMTVLGVLIGLAGGYFGGKIDYW FT LGRITDFFMALPSQLFFVAAMPVITTVFVAPDKETPTYVRAAAIIIVLSFLGWMSMARI FT VRGATMSLRDREFIEAARISGASPWRILRKELLPNIVTPTLVQATLTLPSTILSIAFLS FT FVGVGYVEPTPDWGRMFAIGADIVEQDPYYMLFPGVAMVIFIVAFNLLGDSVRDAFDPK FT GNR" FT misc_feature 188033..188263 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 51.00, E-value 2.6e-11" FT misc_feature 188036..188122 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS 188498..190300 FT /transl_table=11 FT /gene="SCO5113" FT /gene_synonym="bldKB" FT /gene_synonym="SCBAC31E11.09" FT /product="BldKB, putative ABC transport system lipoprotein" FT /note="SCBAC31E11.09, bldKB, possible ABC transport system FT lipoprotein, len: 600 aa; almost identical to TR:P72407 FT (EMBL:U68036) Streptomyces coelicolor BldKB, 602 aa. FT Contains 4x Pfam matches to entry PF00496 SBP_bac_5, FT Bacterial extracellular solute-binding proteins, family 5, FT match to Prosite entry PS00017 ATP/GTP-binding site motif A FT (P-loop) and correctly situated match to Prosite entry FT PS00013 Prokaryotic membrane lipoprotein lipid attachment FT site. Also contains possible N-terminal region signal FT peptide sequence" FT /db_xref="GOA:Q93IU2" FT /db_xref="InterPro:IPR000914" FT /db_xref="UniProtKB/TrEMBL:Q93IU2" FT /protein_id="CAC44320.1" FT /translation="MSILRNRTATAAIVAVAAGALTLTACGGGDSDSSAKDNSKKKEDA FT KSQSKPVQIGDAQASTGPAPEVPGAKPGGTMTVYQTADFSHLDPGQIYVSDGKLLGRLI FT FRGLTQYDEDENGNLTVVGDLATDAGKQTDGGKTWTYTLKDNLKDANGNPINSADIRHT FT IERMYSSYITDGPTYLQQWLSGDGTTYRDAYAGPDKGKHLPDNVLETPDDKTIVFHFKT FT ARPDLPQMLTMPGYSVVPEETDTKEKYDSAPVAAGPYKIAEFKPGKSMKLVKNTQWDPK FT SDSVRHQYVDGFNIEMNHDDEDQTKTLLADQGGAKNAMMFTGQVATTQLQKVVGDKDAM FT KNRTIQGYAPYVWQLNFNMNRVKDKKLRDAITLALPSDSVFKADGGAYGGEVANSLMSP FT TTPGYDEAFDPFGRAKKPNGDIEAAKKLIKEGGFEGKSLVYAYANTPERQKQAVLISTA FT LEKIGLDIQKKEIDSATWYEQVGKVDNGLDLYMTGWGQDWPSASTVIPPVYDGKQIQDG FT ASNYSHINDDHVNSEIQRIQQITDTAEATKAWAELNEYISKEVNPAAPIYYTKVFQIFG FT SNVGGIRYSSDSSYVDVTRVFLKK" FT misc_feature 188543..188575 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature 188546..188635 FT /note="Pfam match to entry PF00496 SBP_bac_5, Bacterial FT extracellular solute-binding proteins, family 5, score FT 1.40, E-value 13" FT misc_feature 188897..188965 FT /note="Pfam match to entry PF00496 SBP_bac_5, Bacterial FT extracellular solute-binding proteins, family 5, score FT 5.20, E-value 1.2" FT misc_feature 189131..189322 FT /note="Pfam match to entry PF00496 SBP_bac_5, Bacterial FT extracellular solute-binding proteins, family 5, score FT 19.80, E-value 9.6e-05" FT misc_feature 189281..189304 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 189584..190291 FT /note="Pfam match to entry PF00496 SBP_bac_5, Bacterial FT extracellular solute-binding proteins, family 5, score FT 8.50, E-value 0.13" FT CDS 190414..191391 FT /transl_table=11 FT /gene="SCO5114" FT /gene_synonym="bldKC" FT /gene_synonym="SCBAC31E11.10" FT /product="BldKC, putative ABC transport system integral FT membrane protein" FT /note="SCBAC31E11.10, bldKC, possible ABC transport system FT integral membrane protein, len: 325 aa; almost identical to FT previously sequenced TR:P72408 (EMBL:U68036) Streptomyces FT coelicolor BldKC, 323 aa. Contains Pfam match to entry FT PF00528 BPD_transp, Binding-protein-dependent transport FT systems inner membrane component. Also contains possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q93IU1" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q93IU1" FT /protein_id="CAC44321.1" FT /translation="MLQFLIRRSFGAVLILVLISAFTFFMFFAIPQDPAMLACGKNCTP FT DALEIIHKNLGLDQPVTVQYWHFLAGIFTGRDFAVGHCDAPCFGVSFANNQNVWDTILD FT RFPLTVSLTVGSLIVFLIVGLGAGLLAAKNRGTWIDKVFSSGSLVVSSLQIYFLGPLVL FT LALVYSTGWLQKPKYVPISEDAAGWFAGLLIPWIVMATIFTANYTRMSRSSMIEQLQEE FT HVRAARAKGMSSNYTFFRYAWRGSLVPIVTILGIDLSALMGGGMVTEMTFGLAGIGRLA FT LESVINKDLPMLMGVMLVSAALIIVFNLIVDAMYAVIDPRVRLS" FT misc_feature 191056..191271 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 25.30, E-value 0.0015" FT RBS 191390..191394 FT CDS 191402..192463 FT /transl_table=11 FT /gene="SCO5115" FT /gene_synonym="bldKD" FT /gene_synonym="SCBAC31E11.11" FT /product="BldKD, putative ABC transporter intracellular FT ATPase subunit" FT /note="SCBAC31E11.11, bldKD, putative ABC transporter FT intracellular ATPase subunit, len: 353 aa; almost identical FT to previously sequenced TR:P72409 (EMBL:U680360) FT Streptomyces coelicolor BldKD putative ABC transporter FT intracellular ATPase subunit, 353 aa and similar to FT TR:O86574 (EMBL:AL031184) Streptomyces coelicolor FT SC2A11.13, 366 aa; fasta scores: opt: 1427 Z-score: 1344.1 FT bits: 257.3 E(): 3.8e-69; 60.340% identity in 353 aa FT overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC FT transporter and match to Prosite entry PS00017 FT ATP/GTP-binding site motif A (P-loop) and PS00211 ABC FT transporters family signature" FT /db_xref="GOA:Q93IU0" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q93IU0" FT /protein_id="CAC44322.1" FT /translation="MTTQTKPEEAPAAAAGDAFLSVRDLKVHFSTEGGVVKAVDGLSFD FT LERGKTLGIVGESGSGKSVTNLAVLGLHDRRRTAIDGSITLDGQELTDASEKQLEKLRG FT KKMAMIFQDALTALSPYYTVGRQIAEPFMKHNGASKKDARVRAIDLLQKVGIPHPQKRV FT DDYPHQFSGGMRQRAMIAMALSCNPDLLIADEPTTALDVTVQAQILDLLKDLQQEFGSA FT IIMITHDLGVVGNMADDIMVMYAGRAVERGTVREVLKSPQHPYTWGLLSSMPNLTSDVD FT EPLMPIPGSPPSLMNPPSGCAFHPRCGFTDLVSGERCSGERPTLPHGRAAACHLTGDQR FT QQVFIEKIQPRLG" FT misc_feature 191546..192139 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 208.90, E-value 7.7e-59" FT misc_feature 191567..191590 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 191909..191953 FT /note="PS00211 ABC transporters family signature" FT CDS 192491..193636 FT /transl_table=11 FT /gene="SCO5116" FT /gene_synonym="SC9E12.01" FT /gene_synonym="bldKE" FT /gene_synonym="SCBAC31E11.12" FT /product="putative peptide transport system ATP-binding FT subunit" FT /note="SC9E12.01, probable peptide transport system FT ATP-binding protein (fragment), len: >142 aa; similar to FT SW:OPPF_ECOLI (EMBL:AE000223) Escherichia coli oligopeptide FT transport protein ATP-binding protein OppF, 334 aa; fasta FT scores: opt: 344 z-score: 423.0 E(): 4.3e-16; 56.5% FT identity in 92 aa overlap and to TR:O86575 (EMBL:AL031184) FT Streptomyces coelicolor oligopeptide ABC transporter FT ATP-binding protein SC2A11.14, 496 aa; fasta scores: opt: FT 488 z-score: 576.6 E(): 1.7e-26; 56.6% identity in 136 aa FT overlap" FT /note="SCBAC31E11.12, bldKE, putative ABC transporter FT intracellular ATPase subunit (fragment), len: >272 aa; FT almost identical to previously sequenced TR:P72410 FT (EMBL:U68036) Streptomyces coelicolor putative ABC FT transporter intracellular ATPase subunit (fragment) BldKE, FT 284 aa and similar to N-terminal region of TR:O86575 FT (EMBL:AL031184) Streptomyces coelicolor SC2A11.14, 497 aa; FT fasta scores: opt: 1186 Z-score: 1170.6 bits: 225.2 E(): FT 1.7e-59; 63.603% identity in 272 aa overlap. Contains Pfam FT match to entry PF00005 ABC_tran, ABC transporter and FT matches to Prosite entries PS00017 ATP/GTP-binding site FT motif A (P-loop) and PS00211 ABC transporters family FT signature" FT /db_xref="GOA:Q8CJS2" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q8CJS2" FT /protein_id="CAD55223.1" FT /translation="MSDNSKTTTAVADDFPQQRDGDTAPLLKVSGLSKHFPIKGGFPIK FT RTVGHVKAVDGVDFEVFPGESLGLVGESGCGKSTTGRLLTRLYEPTQGSIEYRGKDITR FT ANRRELAPVRSEIQMIFQDPYASLNPRQTVGTIISGPMEINGINPPGGREKRVRELLEI FT VGLNPEHYNRFPHEFSGGQRQRIGVARAVALQPKLIVADEPVSALDVSIQAQVVNLLQE FT VQREMGIAFVFIAHDLAIVRHFSQRVAVMYLGKIVEIADRDSLYNRPRHPYTHALLSAV FT PETDLDAEKRERIRLEGDVPSPISPPSGCRFRTRCWKAQDKCATEEPPLVQLSGNREGH FT LTACHFPEEGSTEARAEDIVMDPGLKAMEDGADGGATLSKG" FT misc_feature 192680..193252 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 192.00, E-value 9.3e-54" FT misc_feature 192701..192724 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 193022..193066 FT /note="PS00211 ABC transporters family signature" FT stem_loop 193653..193695 FT /note="possible stem loop. Score 57: 19/19 (100%) matches, FT 0 gaps" FT RBS 193824..193829 FT CDS 193836..195470 FT /transl_table=11 FT /gene="SCO5117" FT /gene_synonym="SC9E12.02" FT /product="putative peptide transport system secreted FT peptide-binding protein" FT /note="SC9E12.02, possible peptide transport system FT secreted peptide-binding protein, len: 544 aa; similar to FT SW:OPPA_BACSU (EMBL:X56347) Bacillus subtilis FT oligopeptide-binding protein OppA precursor, 545 aa; fasta FT scores: opt: 648 z-score: 642.6 E(): 2.5e-28; 26.1% FT identity in 552 aa overlap and to TR:P72407 (EMBL:U68036) FT Streptomyces coelicolor SpoOKA homologue BldKB, 602 aa; FT blastp scores: Score = 165 (58.1 bits), Expect = 2.9e-10, FT Sum P(2) = 2.9e-10; Identities = 116/502 (23%), Positives = FT 202/502 (40%). Contains 2x Pfam matches to entry PF00496 FT SBP_bac_5, Bacterial extracellular solute-binding proteins, FT family 5 and correctly situated match to Prosite entry FT PS00013 Prokaryotic membrane lipoprotein lipid attachment FT site. Also contains possible N-terminal region signal FT peptide sequence" FT /db_xref="GOA:Q9F353" FT /db_xref="InterPro:IPR000914" FT /db_xref="UniProtKB/TrEMBL:Q9F353" FT /protein_id="CAC05747.1" FT /translation="MRGATHARWAACAAAVALAATACGGGGGDGGSGGGSGGVLSSSWG FT DPQNPLEPANTNEVQGGKVLDMIFRGLKKYDPGTGEAQNMLAEKIDTSDSQNFTVTVKD FT GWTFSNGEKVTAQSFVDAWNYGASLKNNQRNAYFFAYIDGYDKVHPESGSQSTDTLSGL FT KVTGPRTFTIKLSQKFSTFPDTLGYPAFAPLPKAFFDDHDAWLKKPVGNGPYQVDNYTR FT GSQMSLRKWDDYPGPDKAQNGGVDLKVYTDNNTAYTDLIAGNLDLVDDVPASQLKNVKN FT DLGDRYINTPAGIIQTLAFPFYDNDWNKSGSEKVRKGLSMAIDRKQITDTIFQNTRTPA FT TDWTSPVLGKDGGYKPGLCGDACEYNAAEAKKLVKEGGGLPGGQVKITYNADTGSHKQW FT VDAVCNSINNALDNDRACAGNPVGTFADFRNQITNQKMSGPFRAGWQMDYPLIQNFLQP FT LYYTNASSNDGKWSSKKFDDLVDQANAETDTAKAVGLFQQAEEVLRDDMGAIPLWYQNG FT SAGYSDRLSNVKLNPFSVPVYNEIKVG" FT misc_feature 193872..193904 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature 193986..194969 FT /note="Pfam match to entry PF00496 SBP_bac_5, Bacterial FT extracellular solute-binding proteins, family 5, score FT 85.80, E-value 3.8e-23" FT misc_feature 195159..195464 FT /note="Pfam match to entry PF00496 SBP_bac_5, Bacterial FT extracellular solute-binding proteins, family 5, score FT 38.20, E-value 7.2e-10" FT RBS 195469..195472 FT CDS 195480..196403 FT /transl_table=11 FT /gene="SCO5118" FT /gene_synonym="SC9E12.03" FT /product="putative peptide transport system integral FT membrane protein" FT /note="SC9E12.03, probable peptide transport system FT integral membrane protein, len: 307 aa; similar to TR: FT SW:OPPB_BACSU (EMBL:X56347) Bacillus subtilis oligopeptide FT transport system permease protein OppB, 311 aa; fasta FT scores: opt: 688 z-score: 788.7 E(): 0; 36.0% identity in FT 308 aa overlap and to TR:P72408 (EMBL:U68036) Streptomyces FT coelicolor SpoOKC homologue BldKC, 323 aa; blastp scores: FT Score = 354 (124.6 bits), Expect = 1.9e-32, P = 1.9e-32; FT Identities = 82/235 (34%), Positives = 138/235 (58%). FT Contains Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component. Also contains possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q9F352" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9F352" FT /protein_id="CAC05748.1" FT /translation="MGRYVVRRLLQMIPVFIGATLLIFLMVNVMGDPIAGLCGDRECDP FT ATAAQLRHEFGLDQPVWQQYATYMGNVFTGDFGTAFNGQPVTELMGTAFPVTIRLTIVA FT ILFEIVVGIILGVLTGLRRGRPVDTGVLLLTLVVISVPTFVTGLLLQLLLGVKWGWIDP FT AVSSEAAFGELIVPGLVLASVSLAYVTRLTRTSIAENRRSDYVRTAIAKGLPRHRVITR FT HLLRNSLIPVVTFIGTDIGALMGGAIVTERIFNIHGVGYQLYQGILRQNTQTVVGFVTV FT LVLVFLVANLVVDLLYAVLDPRIRYA" FT misc_feature 196068..196283 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 24.20, E-value 0.0031" FT CDS 196459..197376 FT /transl_table=11 FT /gene="SCO5119" FT /gene_synonym="SC9E12.04" FT /product="putative peptide transport system integral FT membrane protein" FT /note="SC9E12.04, probable peptide transport system FT integral membrane protein, len: 305 aa; similar to FT SW:OPPC_BACSU (EMBL:X56347) Bacillus subtilis oligopeptide FT transport system permease protein OppC, 305 aa; fasta FT scores: opt: 670 z-score: 745.0 E(): 0; 35.5% identity in FT 296 aa overlap and to TR:P72406 (EMBL:U68036) Streptomyces FT coelicolor SpoOKB homologue BldKA, 335 aa; blastp scores: FT Score = 382 (134.5 bits), Expect = 9.1e-41, Sum P(2) = FT 9.1e-41; Identities = 88/231 (38%), Positives = 134/231 FT (58%). Contains Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component and possible hydrophobic membrane spanning FT regions" FT /db_xref="GOA:Q9F351" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9F351" FT /protein_id="CAC05749.1" FT /translation="MDLGASEAVTLEQPPGPDGADPRDKPRSLWTDAWHDLRRNPVFII FT SALVIIFLIVISIWPSLIASGSPLKCDLAKAQEGSQPGHPFGFNGQGCDVYTRTVYGAR FT TSVAVGILATLGVALLGSVLGGLAGFFGGGGDAVLSRITDIFFAIPVVLGGLVLLSVIT FT SNTIWPVIGFIVLLGWPQISRIARGSVITAKQNDYVQAARALGASNSRLLLRHIAPNAV FT APVIVVATIALGTYISLEATLSFLGVGLKPPSVSWGIDISSAAPYVRNAPHALLWPSGA FT LAITVLAFIMLGDAVRDALDPKLR" FT misc_feature 197026..197256 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 21.60, E-value 0.018" FT CDS 197385..198368 FT /transl_table=11 FT /gene="SCO5120" FT /gene_synonym="SC9E12.05" FT /product="putative peptide transport system ATP-binding FT protein" FT /note="SC9E12.05, probable peptide transport system FT ATP-binding protein, len: 327 aa; similar to SW:OPPD_BACSU FT (EMBL:X56347) Bacillus subtilis oligopeptide transport FT system ATP-binding protein OppD, 358 aa; fasta scores: opt: FT 1126 z-score: 1167.7 E(): 0; 53.9% identity in 310 aa FT overlap, to TR:P72409 (EMBL:U68036) Streptomyces coelicolor FT putative ABC transporter intracellular ATPase subunit FT BldKD, 353 aa; fasta scores: opt: 1035 z-score: 1074.2 E(): FT 0; 51.5% identity in 326 aa overlap and to TR:O86574 FT (EMBL:AL031184) Streptomyces coelicolor oligopeptide ABC FT transporter ATP-binding protein SC2A11.13, 365 aa; fasta FT scores: opt: 1097 z-score: 945.2 E(): 0; 52.3% identity in FT 331 aa overlap. Contains Pfam match to entry PF00005 FT ABC_tran, ABC transporter and matches to Prosite entries FT PS00017 ATP/GTP-binding site motif A (P-loop) and PS00211 FT ABC transporters family signature" FT /db_xref="GOA:Q9F350" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9F350" FT /protein_id="CAC05750.1" FT /translation="MLLEVRDLHVEFHTRDGVAKAVNGVSYGVDAGETLAVLGESGSGK FT SVTAQTIMGILDIPPGRVTAGEILFEGRDLLKLKEEERRKVRGAEMAMIFQDALSSLNP FT VLTVGAQLAEMFTVHRGMSRKDAHAKAVELMDRVRIPAAKERVRQYPHQFSGGMRQRIM FT IAMAMALEPKLIIADEPTTALDVTVQAQVMDLLAELQRELHMGLILITHDLGVVADVAD FT KIAVMYAGRIVETAPVHDIYKAPAHPYTRGLLESIPRLDQKGQELYAIKGLPPNLTRIP FT PGCAFHPRCPMAQDVCRTDVPPLYDVTESDAERGSACHFWRECLHG" FT misc_feature 197478..198074 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 210.40, E-value 2.7e-59" FT misc_feature 197499..197522 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 197844..197888 FT /note="PS00211 ABC transporters family signature" FT RBS 198350..198353 FT CDS 198361..199431 FT /transl_table=11 FT /gene="SCO5121" FT /gene_synonym="SC9E12.06" FT /product="putative peptide transport system ATP-binding FT protein" FT /note="SC9E12.06, probable peptide transport system FT ATP-binding protein, len: 356 aa; similar to SW:APPF_BACSU FT (EMBL:U20909) Bacillus subtilis oligopeptide transport FT ATP-binding protein AppF, 329 aa; fasta scores: opt: 1255 FT z-score: 1332.6 E(): 0; 57.3% identity in 335 aa overlap, FT to TR:P72410 (EMBL:U68036) Streptomyces coelicolor putative FT ABC transporter intracellular ATPase subunit BldKE FT (fragment), 284 aa; fasta scores: opt: 999 z-score: 1063.6 FT E(): 0; 58.1% identity in 260 aa overlap and to TR:O86575 FT (EMBL:AL031184) Streptomyces coelicolor oligopeptide ABC FT transporter ATP-binding protein SC2A11.14, 496 aa; fasta FT scores: opt: 1306 z-score: 1117.3 E(): 0; 55.4% identity in FT 345 aa overlap. Contains Pfam match to entry PF00005 FT ABC_tran, ABC transporter and matches to Prosite entries FT PS00017 ATP/GTP-binding site motif A (P-loop) and PS00211 FT ABC transporters family signature" FT /db_xref="GOA:Q9F349" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9F349" FT /protein_id="CAC05751.1" FT /translation="MAETTEPILEVRGLVKHYPLTSGILFKKQVGAVKAVDGVDFRLAR FT GETLGIVGESGCGKSTVAKMLVNLERPTAGEIRYKGEDITRLSGRALKSVRRNIQMVFQ FT DPYTSLNPRMTVGDIIGEAYDIHPEVAPKGDRRRRVQDLLDVVGLNPEYINRYPHQFSG FT GQRQRIGIARGLALRPEIIVADEPVSALDVSVQAQVINLMARLQDEFDLSYIFIAHDLS FT IVRHISDRVGVMYLGRIVETGRDEEIYDHPTHPYTQALLSAVPVPDPEAREHRERIILS FT GDVPSPTNIPSGCRFRTRCWKARERCALEVPALAVPAEFRSVSGPAAHDSACHFAEEKQ FT VVPPEGEGEGEGSGPG" FT misc_feature 198496..199071 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 223.20, E-value 3.9e-63" FT misc_feature 198517..198540 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 198841..198885 FT /note="PS00211 ABC transporters family signature" FT CDS complement(199564..201687) FT /transl_table=11 FT /gene="SCO5122" FT /gene_synonym="SC9E12.07c" FT /product="putative peptidase" FT /note="SC9E12.07c, probable peptidase, len: 707 aa; similar FT to TR:P95782 (EMBL:D83263) Xanthomonas maltophilia FT dipeptidyl peptidase IV, 741 aa; fasta scores: opt: 442 FT z-score: 478.1 E(): 3.7e-19; 33.2% identity in 733 aa FT overlap. Contains Pfam matches to entries PF00930 FT DPPIV_N_term, Dipeptidyl peptidase IV (DPP IV) N-terminal FT region and PF00326 Peptidase_S9, Prolyl oligopeptidase FT family and match to Prosite entry PS00708 Prolyl FT endopeptidase family serine active site" FT /db_xref="GOA:Q9F348" FT /db_xref="InterPro:IPR002471" FT /db_xref="UniProtKB/TrEMBL:Q9F348" FT /protein_id="CAC05752.1" FT /translation="MTTESDSFPKRHARTQRFTLGAPRSFTVAPDGSRVAFLRSGTGTD FT RANSLWVLDAEKGGERMAADPRALLGGAQERLSPEERARRERSREGGAGIVGYATDSSV FT ELASFALSGRLFVAELQVGTARELPTPGPVIDPRPSPDGRHVAYVAQGALRVVGAEGDG FT DRALAEADGEGVTYGLAEFVAAEEMSRSRGFWWSPESDRLLVARVDDTPVQRWWISDPA FT HPGRDPQHVPYPAAGTPNADVRLFVVGLDGGRTEVLWDRARYPYLARVHWSAAGAPLLL FT VQARDQRSQLFLAVDTESGTTRMVHADEDPIWLELFPGVPYWSPSGQLVRIADEGGARV FT LAVGERLLTGAQLHLRAVLDVGADDVLVSASAGEEAAEAEIGEVHVYRVNELGVERLSQ FT EPGVHSAVRAGGVTVLVSATLDRPGARVRVLRDGKAAATIASYAEDPGLSPRVTLTQGG FT ARRVPCAVLMPTDYHGDTPLPVLLDPYGGPHGQRVVAAHNAHLTSQWFADQGFAVVVAD FT GRGTPGRSPAWEKAVKDDVAAVVLQDQVDALHALAADFPLDLDRVAVRGWSFGGYLAAL FT AALRRPDVFHAAVVGAPVTDLRLYDTHYQERYLGDPGEQPDVYRRNSVIDDAGLVDAAE FT PHRPMMVIHGLADDNVVVAHSLRLSSALLAAGRPHEVLPLSGVTHMTPQESVAENLLRL FT QVDFLKRSLPAPA" FT misc_feature complement(199969..200061) FT /note="PS00708 Prolyl endopeptidase family serine active FT site" FT misc_feature complement(199969..200166) FT /note="Pfam match to entry PF00326 Peptidase_S9, Prolyl FT oligopeptidase family, score 29.60, E-value 7.3e-08" FT misc_feature complement(200203..201636) FT /note="Pfam match to entry PF00930 DPPIV_N_term, Dipeptidyl FT peptidase IV (DPP IV) N-terminal region, score -82.80, FT E-value 5.4e-07" FT RBS 201860..201867 FT CDS 201874..202068 FT /transl_table=11 FT /gene="SCO5123" FT /gene_synonym="SC9E12.08" FT /product="putative small membrane protein" FT /note="SC9E12.08, possible small membrane protein, len: 64 FT aa; similar to TR:Q9RKX4 (EMBL:AL133213) Streptomyces FT coelicolor putative secreted protein SC6D7.24c, 64 aa; FT fasta scores: opt: 225 z-score: 329.1 E(): 7.3e-11; 56.5% FT identity in 62 aa overlap. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9F347" FT /protein_id="CAC05753.1" FT /translation="MALSISAVVLLAIIVFLLVKKSGLKAGHAVVCMLLGFYLASSTIA FT PTISELTTNIAGMIGDINF" FT CDS complement(202058..202264) FT /transl_table=11 FT /gene="SCO5124" FT /gene_synonym="SC9E12.09c" FT /product="hypothetical protein" FT /note="SC9E12.09c, hypothetical protein, len: 68 aa; FT similar to TR:Q9RDR5 (EMBL:AL136500) Streptomyces FT coelicolor hypothetical 7.7 kDa protein SC1G2.14c, 73 aa; FT fasta scores: opt: 217 z-score: 327.7 E(): 8.7e-11; 55.9% FT identity in 59 aa overlap" FT /db_xref="InterPro:IPR007278" FT /db_xref="UniProtKB/TrEMBL:Q9F346" FT /protein_id="CAC05754.1" FT /translation="MIRTSSSTGLVWSKSSYSSGGETDSCVEVALAPGTVHVRDSKNLP FT DTGPRLALAPEAWGCFVAGTVRS" FT CDS complement(202261..203124) FT /transl_table=11 FT /gene="SCO5125" FT /gene_synonym="SC9E12.10c" FT /product="conserved hypothetical protein" FT /note="SC9E12.10c, hypothetical protein, len: 287 aa; FT similar to TR:Q9RDR4 (EMBL:AL136500) Streptomyces FT coelicolor hypothetical 31.7 kDa protein SC1G2.15c, 284 aa; FT fasta scores: opt: 1240 z-score: 1466.1 E(): 0; 67.2% FT identity in 287 aa overlap" FT /db_xref="GOA:Q9F345" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q9F345" FT /protein_id="CAC05755.1" FT /translation="MSVDAGTDQVDEPGWEVDPDDDWALAVIATVGRQLRLRREAAGMR FT APDFAVAIGYGEDLVYKVEGGRRIPRPEYLDRADEVLTAGGLVAAMKEDVKKVRYPKKV FT RDLAQMEARAVELQLYDPVNVHGLLQTPDYARALFRMRRPRYAEDEIERGVAARTARKA FT VFERDPAPELGFVQDEWTLRRRLGGTDVVRRQLEHLLMLGRLPNVEIQVMPMDREEHAG FT VDGAIEVLKFEDGTAVGRSPGVANGRPVTDLRQVRILELRYGIIRAQALTPCESAAFIE FT QLLGET" FT RBS complement(202267..202270) FT RBS complement(203133..203139) FT CDS 203276..204163 FT /transl_table=11 FT /gene="SCO5126" FT /gene_synonym="SC9E12.11" FT /product="conserved hypothetical protein" FT /note="SC9E12.11, hypothetical protein, len: 295 aa; FT similar to TR:O50426 (EMBL:AL010186) Mycobacterium FT tuberculosis hypothetical 31.7 kDa protein MTV005.06, 303 FT aa; fasta scores: opt: 531 z-score: 607.8 E(): 2.2e-26; FT 44.4% identity in 306 aa overlap" FT /db_xref="HSSP:1UAN" FT /db_xref="InterPro:IPR017810" FT /db_xref="UniProtKB/TrEMBL:Q9F344" FT /protein_id="CAC05756.1" FT /translation="MTDLPGRRLLLVHAHPDDESINNGVTMARYAAEGAHVTLVTCTLG FT ERGEVIPPALAHLSGAALGGHRRGELADAMRALGVDDFRLLGGPGRYADSGMLGLSDND FT DPGCLWQADVDAAAALLVDVIREVRPQVLVTYDPNGGYGHPDHIQAHRIAMRAAELAAE FT AGCPVAKVYWNRVPRSRVEDAFARLRDDLPGLPFEKAAGVEDVPGVVDDERITTEIRGE FT GTAYAAAKAAAMRAHATQITVAEPYFVLSNDLAQPILTTEYYELVRGERGGEGRENDLF FT AGIAGTFDTGEATS" FT RBS 204148..204152 FT CDS 204160..204582 FT /transl_table=11 FT /gene="SCO5127" FT /gene_synonym="SC9E12.12" FT /product="putative integral membrane protein" FT /note="SC9E12.12, possible integral membrane protein, len: FT 1450 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9F343" FT /protein_id="CAC05757.1" FT /translation="MNGRNEPPSSALAQPLRPPSLGRAALYAGLFVLGAVLGVAGALLQ FT PAWFPGGLLLALAAEAGLCAGAGRAVGRRGGAVAPALGWALAVVLLTTSRPEGDFLFAA FT GAGSYLFLLGGIAVAVICATLAPVRQPDGGPARLRK" FT RBS 204726..204729 FT CDS 204738..207065 FT /transl_table=11 FT /gene="SCO5128" FT /gene_synonym="SC9E12.13" FT /product="putative membrane protein" FT /note="SC9E12.13, possible membrane protein, len: 775 aa; FT highly hydrophilic. Contains possible hydrophobic membrane FT spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9F342" FT /protein_id="CAC05758.1" FT /translation="MSRETDSSSSGPHGRGGAAYPSGTPPYGTPTASDAGADAGRSATR FT PEERKTETTLTTRIRINIPGSRPIPPVVVRKPVADGEDTADSTETTGERPAPAPSAAAP FT GAAAPEAPAESAQSAQSAEEKPTSDWFAPRKSGPGKGTQGGGSTNGAGLPAGSAPTAGT FT PGAAGARGAGPAGASGAGARPGGGSGRPGGVVGSMNAPGGARSGSAGGGARSGATGGPV FT APGHGGGTGSFDVTEALAAGPLGGNGNGNGNGNGSGPRPGTDAGGEPRRDDLPYFAGEG FT RADQAPGGQQNGLNGQSPYGTGPQGPAGPTSGPATGDSRLTPPPAGDLGGLGTAGGPAA FT PGTQREPAPNGLRGPGSLGGPGGPGGPGRPAGSGPDAARLGPGGGLSDDTAILTPQRPV FT PPGAANPDNISGNTVTSGIPVVPGERTAPFPAGSGDGPRPHTPPKLPEPVSAPPASSAK FT PAKKKGRRKLPLLVVGVVVVAGVTYGAGLLMNRSDVPKGTTVLGVDIGGGTRDDAVEKL FT DKALGARAAKPLKLTVGGDTVSLKPDQAGLQLDTQTTASSAATSDYNPMSVIGSLFGQK FT RVVEPAMPVDEEKLHAALEDAAGGAGSATEGSIRFESGKAVPVYGKAGQGIDVAKSTEA FT VQAAYRAQVETGTATAVNVPTTAKQPTVAKAEVDRMLKEFAEPAMSARVTVQTDAAHSI FT QFSPEKSLWKFLRVTAVDGKLVDKPDLNALKELYGQTFDGVLIARANGEKTAVTPQDVY FT GAMRQALKSKTDRVAVIDTNPS" FT misc_feature 205164..205892 FT /note="high content region in alanine, glycine and proline FT amino acid residues. High G+C content also (81.61%)" FT CDS 207212..208168 FT /transl_table=11 FT /gene="SCO5129" FT /gene_synonym="SC9E12.14" FT /product="putative ABC transporter ATP-binding protein" FT /note="SC9E12.14, possible ABC transporter ATP-binding FT protein, len: 318 aa; similar to TR:CAB88183 FT (EMBL:AL352972) Streptomyces coelicolor putative ABC FT transporter ATP-binding protein SCC30.13, 308 aa; fasta FT scores: opt: 861 z-score: 926.3 E(): 0; 54.4% identity in FT 309 aa overlap. Contains Pfam match to entry PF00005 FT ABC_tran, ABC transporter and matches to Prosite entries FT PS00017 ATP/GTP-binding site motif A (P-loop) and PS00211 FT ABC transporters family signature" FT /db_xref="GOA:Q9F341" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9F341" FT /protein_id="CAC05759.1" FT /translation="MTRTTAVGFDRVTKGYGDVRAVDGLTLALHPGETVALLGPNGAGK FT STTLDLLLGLRRPDAGTVHVFGGEPREAVVAGRVGAMLQSGGLMDEVTVAELVRLGCAL FT HPRAYPAADVLARAGLTKIADRRVDKLSGGQAQRVRFALATAGDSDLIVLDEPTTGMDV FT TARQAFWATMREQADQGRTVLFATHYLEEADAIADRVLVLHRGRLLADGTAAEIKARAG FT TRRISFDLDGGPDASPDASPDGSRNGTVDEATLRALPHLTALDVSGRTVRIQSADADAT FT VYALYGLGLYPRNLEVAGLGLEQAFVALTAAEEAKQP" FT misc_feature 207305..207829 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 180.30, E-value 3.2e-50" FT misc_feature 207326..207349 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 207602..207646 FT /note="PS00211 ABC transporters family signature" FT RBS 208149..208154 FT CDS 208165..208905 FT /transl_table=11 FT /gene="SCO5130" FT /gene_synonym="SC9E12.15" FT /product="putative ABC transporter integral membrane FT protein" FT /note="SC9E12.15, possible ABC transporter integral FT membrane protein, len: 246 aa; similar to TR:CAB88184 FT (EMBL:AL352972) Streptomyces coelicolor putative ABC FT transporter integral membrane protein SCC30.14, 238 aa; FT fasta scores: opt: 516 z-score: 611.2 E(): 1.4e-26; 35.9% FT identity in 237 aa overlap. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q9F340" FT /db_xref="InterPro:IPR013525" FT /db_xref="UniProtKB/TrEMBL:Q9F340" FT /protein_id="CAC05760.1" FT /translation="MNGLIKLELTRALRNRKFLFFSVIYPSALFLLIAGSADATSEVDG FT TGLTLPTFFMVSMASFGALTAVLMGNSERIAKERESGWVRQLRLTALPGRGYVLAKTAS FT AAVVSLPSVVVVFVVAAAVKDVRLHAWQWLALTGVIWAGSLVFAALGVAIGYLATGDAV FT RPITMIVYFGLSMLGGLWMPTTTFPQWLRDVAEWLPTHAYAALGQSIEQSHAPHAQDLA FT VLAVYFVLFAGGAAWLYRKDTLKA" FT CDS 208902..210068 FT /transl_table=11 FT /gene="SCO5131" FT /gene_synonym="SC9E12.16" FT /product="putative two-component system sensor kinase" FT /note="SC9E12.16, possible two-component system sensor FT kinase, len: 388 aa; similar to TR:CAB88185 (EMBL:AL352972) FT Streptomyces coelicolor putative two-component system FT sensor kinase SCC30.15, 409 aa; fasta scores: opt: 773 FT z-score: 840.8 E(): 0; 41.9% identity in 389 aa overlap. FT Contains possible hydrophobic membrane spanning regions at FT N-terminal domain" FT /db_xref="GOA:Q9F339" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9F339" FT /protein_id="CAC05761.1" FT /translation="MSGVGIGQRPENRRQKTVKVMWTAIWLAYLGAPVSDLLHGGHAVG FT VQVLGWIGLVAFVVWYMLLLFRTGRGERTRLVLGSLAVLAAESTLLALTLGREWLVLFV FT YVAIASGAALPLRLARWTIPGASALLTAMALVVPGGTSFIAGLLLPALLGGFAMTGVRE FT LVRTTIALREARATVAQLAANEERLRLARDLHDLLGHSLSLITLKSELAGRMLPAHPDK FT AAQQVADIEQVSRQALVDVREAVTGYRRARLAPELAGAKVALTAAGVDAELPGEPDPAH FT LPEDSEAALAWALREAVTNVVRHSGARRCVVELLERQTLDGAVLELSVEDNGSGGPASA FT NAPGNGLTGLAERLEKAGGTLEAGGSRRGFRLVARVPVGAATDVGSGA" FT CDS 210065..210679 FT /transl_table=11 FT /gene="SCO5132" FT /gene_synonym="SC9E12.17" FT /product="putative two-component system response regulator" FT /note="SC9E12.17, possible two-component system response FT regulator, len: 204 aa; similar to TR:CAB88186 FT (EMBL:AL352972) Streptomyces coelicolor putative FT two-component response regulator SCC30.16, 210 aa; fasta FT scores: opt: 822 z-score: 928.1 E(): 0; 63.0% identity in FT 200 aa overlap. Contains Pfam matches to entries PF00072 FT response_reg, Response regulator receiver domain and FT PF00196 GerE, Bacterial regulatory proteins, luxR family. FT Also contains possible helix-turn-helix motif at residues FT 159..180 (+5.28 SD)" FT /db_xref="GOA:Q9F338" FT /db_xref="HSSP:1FSE" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9F338" FT /protein_id="CAC05762.1" FT /translation="MSRTIKVLLAEDQAMVREALAALLGLEEDIEVVAQVARGDEVLDA FT ARAHGVDVALLDIEMPGATGIEAAALVHRELPAVKLVVLTTFGRPGYLRSAMESGADAF FT LVKDAPAAQLAEAVRRVLAGERVIDPTLAAAALAEGANPLTDREREILRAAADGSTNAE FT LASALHLSQGTVRNYLSTAIQKLAVRNRAEAVRVARNKGWL" FT misc_feature 210077..210418 FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 100.50, E-value 3.2e-26" FT misc_feature 210485..210676 FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 65.30, E-value FT 1.3e-15" FT CDS complement(210789..211685) FT /transl_table=11 FT /gene="SCO5133" FT /gene_synonym="SC9E12.18c" FT /product="conserved hypothetical protein" FT /note="SC9E12.18c, hypothetical protein, len: 298 aa; FT C-terminal highly similar to N-terminal domain of TR:Q07641 FT (EMBL:AB006206) Streptomyces griseus hypothetical 34.5 kDa FT protein in AmfR 3'region (fragment), 87 aa; fasta scores: FT opt: 371 z-score: 414.3 E(): 1.3e-15; 63.2% identity in 87 FT aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9F337" FT /protein_id="CAC05763.1" FT /translation="MRPPRPPRPPSPQRSAELRRRFAQEARSERPDLATLCLLVGAEAD FT GTLDEAGLDAAQVELDRLAGELPFRPGTPRAWAVALRDLLGERYGFHGVAADYQRLESS FT LLHEVVRRRRGLPILLSVVWLEVARRAGAPVYGVALPGHFVVGFGGESAAASGPGSAPL FT GERVLVDPYDGGRLLSGTDAEALVAGATGAELRASMLEPAAPLDVVARVLNNIRAWAAA FT RPEQSAVGLWAVELALLLPAHAARLRYERAVLLVQRGEFAAGAGELEAYAEVVEAVDEA FT VAEEVRGEARTARAMLN" FT repeat_region complement(211656..211682) FT CDS complement(211727..212761) FT /transl_table=11 FT /gene="SCO5134" FT /gene_synonym="SC9E12.19c" FT /product="hypothetical protein" FT /note="SC9E12.19c, hypothetical protein, len: 344 aa; FT highly similar to TR:O87087 (EMBL:AB006206) Streptomyces FT griseus AmfR, AmfA and AmfB genes and 4 ORFS, complete CDS, FT ORF5, 264 aa; fasta scores: opt: 1018 z-score: 1086.7 E(): FT 0; 63.3% identity in 264 aa overlap. Contains Pfam match to FT entry PF00583 Acetyltransf, Acetyltransferase (GNAT) FT family" FT /db_xref="GOA:Q9F336" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9F336" FT /protein_id="CAC05764.1" FT /translation="MEFSAAGRLEVRITTADVGKRVSVRRLSEAGAAGEKFTDTVGVLT FT SWTDGVLLITRKSGESVRVAESALVAGKVVPPAPARRRGPAASYEELARVAARSWRPVE FT SERLGAWELRAAGGFTRRANSVLPLGDPGLPLDEALTAVRRWYGVRGLPAYVQTATGAA FT GTQELLCAELERRGWVREVTAEVWTGPLAPVADLAGDTGVVLSREADETWLARYQRKGV FT SEVALRVLESGPSVWFATVPGAEGADGAGGGGGVAAIGRCVVDGRWASFAAVEVDPAQR FT RRGLATAVMAALARRALDEGASAAWLQVETDNAGARALYAGMGFAAHHSYHHYREPAAA FT GTDR" FT misc_feature complement(211784..212008) FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 55.30, E-value FT 1.4e-12" FT RBS 212887..212892 FT CDS 212902..213222 FT /transl_table=11 FT /gene="SCO5135" FT /gene_synonym="fdxA1" FT /gene_synonym="SC9E12.20" FT /product="ferredoxin" FT /note="SC9E12.20, fdxA1, ferredoxin, len: 106 aa; similar FT to SW:FER_SACER (EMBL:M61119) Saccharopolyspora erythraea FT ferredoxin FdxA, 105 aa; fasta scores: opt: 618 z-score: FT 759.8 E(): 0; 78.1% identity in 105 aa overlap and to FT TR:CAC04216 (EMBL:AL391515) Streptomyces coelicolor FdxA, FT ferredoxin, 129 aa; fasta scores: opt: 520 z-score: 702.1 FT E(): 1.8e-33; 65.7% identity in 105 aa overlap. Contains FT Pfam match to entry PF00037 fer4, 4Fe-4S binding domain and FT match to Prosite entry PS00198 4Fe-4S ferredoxins, FT iron-sulfur binding region signature" FT /db_xref="GOA:Q9F335" FT /db_xref="HSSP:1BD6" FT /db_xref="InterPro:IPR000813" FT /db_xref="UniProtKB/TrEMBL:Q9F335" FT /protein_id="CAC05765.1" FT /translation="MTYVIAQPCVDVKDKACIEECPVDCIYEGQRSLYIHPDECVDCGA FT CEPVCPVEAIFYEDDTPEEWKDYYKANVEFFDELGSPGGASKLGLIERDHPFVAALPPQ FT NQ" FT misc_feature 212998..213069 FT /note="Pfam match to entry PF00037 fer4, 4Fe-4S binding FT domain, score 37.10, E-value 3.9e-07" FT misc_feature 213019..213054 FT /note="PS00198 4Fe-4S ferredoxins, iron-sulfur binding FT region signature" FT stem_loop 213242..213297 FT /note="possible stem loop. Score 50: 18/19 (94%) matches, 0 FT gaps" FT RBS 213326..213329 FT CDS 213339..214436 FT /transl_table=11 FT /gene="SCO5136" FT /gene_synonym="SC9E12.21" FT /product="putative aminotransferase" FT /note="SC9E12.21, probable aminotransferase, len: 365 aa; FT similar to TR:O50434 (EMBL:AL010186) Mycobacterium FT tuberculosis aminotransferase MTV005.14, 362 aa; fasta FT scores: opt: 1448 z-score: 1704.1 E(): 0; 61.7% identity in FT 360 aa overlap. Contains match to Prosite entry PS00105 FT Aminotransferases class-I pyridoxal-phosphate attachment FT site" FT /db_xref="GOA:Q9F334" FT /db_xref="InterPro:IPR019880" FT /db_xref="UniProtKB/TrEMBL:Q9F334" FT /protein_id="CAC05766.1" FT /translation="MSAVSDRLPTFPWDKLEPYKKTAAAHPGGIVDLSVGTPVDPVPEL FT IQKALVDAADSPGYPTVWGTPALRDAITGWVERRLGARDVTHRHVLPVVGSKELVAWLP FT TQLGLGPGDRVAFPRLAYPTYEVGARLARAEYEAYEDPTELDPAGLKLLWLNSPSNPTG FT KVLSKADLTRIVAWAREHGVLVVSDECYLELGWEADPVSVLHPDVNGGSYDGLVAVHSL FT SKRSNLAGYRAAFLAGDPAVLGPLLEIRKHGGMMTPAPTQAAVVAALGDDEHVRVQRER FT YAARRTVLREALLGAGFRIEHSEASLYLWATRGESCWETVAHLAERGILVAPGDFYGPA FT GAHFVRVALTATDDRVQAAADRLRS" FT misc_feature 213999..214040 FT /note="PS00105 Aminotransferases class-I FT pyridoxal-phosphate attachment site" FT CDS complement(214655..215086) FT /transl_table=11 FT /gene="SCO5137" FT /gene_synonym="SC9E12.22c" FT /product="putative ATP-binding protein" FT /note="SC9E12.22c, possible ATP-binding protein, len: 143 FT aa. Contains match to Prosite entry PS00017 ATP/GTP-binding FT site motif A (P-loop). Contains possible hydrophobic FT membrane spanning region" FT /db_xref="GOA:Q9F333" FT /db_xref="InterPro:IPR017909" FT /db_xref="UniProtKB/TrEMBL:Q9F333" FT /protein_id="CAC05767.1" FT /translation="MSLPLTRRIARAALLVAAGAAAGVGAAGSASAAPELPATPNLGGL FT TALDGANVGNTAASAAESATETAGDTGGKAVKKAVPTAGKTGGSVVKKATPAAQNAAGD FT AAGSAGDIVGDTAATATKGGLPTDALGKGGLPVQGLPLG" FT misc_feature complement(214829..214852) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(215091..215096) FT CDS complement(215424..216392) FT /transl_table=11 FT /gene="SCO5138" FT /gene_synonym="SCP8.01c" FT /gene_synonym="SC9E12.23c" FT /product="putative membrane protein" FT /note="SCP8.01c, possible membrane protein (fragment), len: FT >86 aa.. Contains possible hydrophobic membrane spanning FT region" FT /note="SC9E12.23c, hypothetical protein (fragment), len: FT >270 aa; similar to TR:Q9X867 (EMBL:AL049661) Streptomyces FT coelicolor putative lipoprotein SCE134.12, 381 aa; fasta FT scores: opt: 432 z-score: 481.0 E(): 2.5e-19; 41.2% FT identity in 211 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q8CJS1" FT /protein_id="CAD55224.1" FT /translation="MLQPSPPRKRRGRLARSGAASMVLLAVAGYLAVQYVTGGAFAPGC FT KVAGGKGGRTTYEFTPEQAVNAATITAVGTARKLPDRAVTIALAAALQESALRNLDHGD FT KDSLGLFQQRPSQGWGKPEEIMDPAYSAGLFYDHLVEVPGYLDLPLTDAAQRVQRSAFP FT DAYAKHEPDAELLAAALTGRSAATLTCVGRPGATPEKGPDAVRAALVRDFGHDVLRPAG FT AEVGGDAASRRPATGSDERTVTLPVTGSTGSGPAREHVRRGWQLAHWAVANASSLHIQR FT VTYAGREWTAGNTDSKWYPTGTEGAKGAERAAEAVRITSAR" FT CDS 216476..217555 FT /transl_table=11 FT /gene="SCO5139" FT /gene_synonym="dapE" FT /gene_synonym="SCP8.02" FT /product="succinyl-diaminopimelate desuccinylase" FT /note="SCP8.02, dapE, succinyl-diaminopimelate FT desuccinylase, len: 359 aa; highly similar to SW:DAPE_CORGL FT (EMBL:X81379) Corynebacterium glutamicum FT succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) DapE, FT 369 aa; fasta scores: opt: 1189 z-score: 1383.5 E(): 0; FT 52.1% identity in 361 aa overlap. Contains Pfam match to FT entry PF01546 Peptidase_M20, Peptidase family M20/M25/M40" FT /db_xref="GOA:Q9FBL9" FT /db_xref="InterPro:IPR011650" FT /db_xref="UniProtKB/TrEMBL:Q9FBL9" FT /protein_id="CAC01340.1" FT /translation="MADTPLDLTLDAAELTARLVDFPSESGTEKPLADAIESALRTLPH FT LSVERYGNNLVARTGLGRAERVILAGHIDTVPIAGNVPSRLDEDGVLWGCGTCDMKAGV FT AVQLRIAATVPAPNRDLTFVFYDNEEVAAELNGLKHVAEAHPEWLEGDFAVLLEPSDGQ FT VEGGCQGTLRVLLKTAGERAHSARSWMGSNAIHAAAPILARLAAYEPRYPVIDGLEYRE FT GLNAVGITGGVAGNVIPDECVVTVNFRYAPDRSPEEALAHVREVFDGCGVTDFVVDDHS FT GAALPGLSHPAAAAFIEAVGGTPQPKYGWTDVSRFSALGVPAVNYGPGNPHLAHKRDER FT VEVAKILAGEERLRSWLTA" FT misc_feature 216521..217282 FT /note="Pfam match to entry PF01546 Peptidase_M20, Peptidase FT family M20/M25/M40, score 165.00, E-value 2.1e-46" FT CDS 217673..218431 FT /transl_table=11 FT /gene="SCO5140" FT /gene_synonym="SCP8.03" FT /product="conserved hypothetical protein" FT /note="SCP8.03, hypothetical protein, len: 252 aa; similar FT to TR:Q46063 (EMBL:X81379) Corynebacterium glutamicum ORF2, FT 211 aa; fasta scores: opt: 938 z-score: 1070.3 E(): 0; FT 67.1% identity in 210 aa overlap" FT /db_xref="InterPro:IPR005269" FT /db_xref="UniProtKB/TrEMBL:Q9FBL8" FT /protein_id="CAC01341.1" FT /translation="MATGNPEGKKRPPEEQRLGPVLRRRGQVQESTTDQRLLDERAPTD FT WVHTDPWRVLRIQSEFIEGFGTLAELPPAISVFGSARTPADSPEYDAGVRLGRGLVEAG FT FAVITGGGPGAMEAANKGALEAKGTSVGLGIELPFEQGLNPYVDIGLNFRYFFVRKMMF FT VKYAQGFVVLPGGLGTLDELFEALTLVQTQKVTRFPIVLFGSEYWGGLVDWLRGTLVAQ FT GKAAEKDLMLFHVTDDVDEAVALVSKEAGR" FT CDS complement(218682..219566) FT /transl_table=11 FT /gene="SCO5141" FT /gene_synonym="folP" FT /gene_synonym="SCP8.04c" FT /product="dihydropteroate synthase" FT /note="SCP8.04c, folP, dihydropteroate synthase, len: 294 FT aa; similar to SW:DHPS_MYCLE (EMBL:U15180) Mycobacterium FT leprae dihydropteroate synthase (EC 2.5.1.15) (DHPS) FolP, FT 291 aa; fasta scores: opt: 1095 z-score: 1239.8 E(): 0; FT 60.6% identity in 292 aa overlap. Contains Pfam match to FT entry PF00809 DHPS, Dihydropteroate synthase and matches to FT Prosite entries PS00792 Dihydropteroate synthase signature FT 1 and PS00793 Dihydropteroate synthase signature 2" FT /db_xref="GOA:Q9FBL7" FT /db_xref="HSSP:1AD1" FT /db_xref="InterPro:IPR006390" FT /db_xref="UniProtKB/TrEMBL:Q9FBL7" FT /protein_id="CAC01342.1" FT /translation="MDQEMSQGMLRLGRREFAAHEPVIMAIVNRTPDSFYDRGATFGDE FT PALARVEQAVAEGAAIIDVGGVKAGPGDEVSAAEEARRTVGFVAEVRRRHPDVVISVDT FT WRHEVGEAVCEAGADLLNDAWGGVDPKLAEVAARYGVGLVCTHAGGAEPRTRPHRVTYD FT DVVADVLRVTLGLAERAVGLGVPRESVLIDPGHDFGKNTRHSLEATRRLGEMVETGWPV FT LVSLSNKDFVGETLDRPVKERLIGTLATTAVSAWLGARVYRVHEVAETRQVLDMVATIA FT GHREPAVARRGLA" FT misc_feature complement(218730..219494) FT /note="Pfam match to entry PF00809 DHPS, Dihydropteroate FT synthase, score 330.90, E-value 1.4e-95" FT misc_feature complement(219354..219395) FT /note="PS00793 Dihydropteroate synthase signature 2" FT misc_feature complement(219450..219497) FT /note="PS00792 Dihydropteroate synthase signature 1" FT CDS 219711..220070 FT /transl_table=11 FT /gene="SCO5142" FT /gene_synonym="SCP8.05" FT /product="putative secreted protein" FT /note="SCP8.05, possible secreted protein, len: 119 aa. FT Contains possible coiled-coil region at approx residues FT 77..95 and N-terminal region signal peptide sequence" FT /db_xref="InterPro:IPR019933" FT /db_xref="UniProtKB/TrEMBL:Q9FBL6" FT /protein_id="CAC01343.1" FT /translation="MVMFLFLVIALAVVVAAVTLAVVGGGESGPLPDAAPERVRDALPP FT DRPVGRGDVERLRFPLVVRGYRMADVDDALGRLGAELAEREARIADLESALAGARAAAA FT HRHVVMDKPDREEQQ" FT RBS 220057..220061 FT CDS 220067..220651 FT /transl_table=11 FT /gene="SCO5143" FT /gene_synonym="tag" FT /gene_synonym="SCP8.06" FT /product="DNA-3-methyladenine glycosylase I" FT /note="SCP8.06, tag, DNA-3-methyladenine glycosylase I, FT len: 194 aa; highly similar to SW:3MG1_ECOLI (EMBL:J02606) FT Escherichia coli DNA-3-methyladenine glycosylase I (EC FT 3.2.2.20) Tag, 187 aa; fasta scores: opt: 529 z-score: FT 636.5 E(): 5.5e-28; 45.2% identity in 177 aa overlap" FT /db_xref="GOA:Q9FBL5" FT /db_xref="HSSP:1NKU" FT /db_xref="InterPro:IPR004597" FT /db_xref="UniProtKB/TrEMBL:Q9FBL5" FT /protein_id="CAC01344.1" FT /translation="MSAGEAVAGPDGALRCPWALSTADYVTYHDDEWGRPVHGDDALYE FT RLSLEAFQSGLSWITILRRRTGFRSAFAGFEIAKVAAFTDTDRERLLADTGIIRNRAKI FT DATLTNARVLAEWAPGDLDELIWSHAPDPAGRPAPKTLTDVPAVTPESTALSKALKKRG FT LRFVGPTTAYALMQACGLVDDHLAACVARRP" FT CDS complement(221303..222106) FT /transl_table=11 FT /gene="SCO5144" FT /gene_synonym="SCP8.07c" FT /product=" putative acyl CoA isomerase" FT /note="SCP8.07c, probable acyl CoA isomerase, len: 267 aa; FT highly similar to TR:AAF73478 (EMBL:AF268489) Streptomyces FT collinus 2-cyclohexenylcarbonyl CoA isomerase ChcB, 269 aa; FT fasta scores: opt: 1476 z-score: 1623.5 E(): 0; 87.6% FT identity in 266 aa overlap and to SW:CRT_CLOAB FT (EMBL:U17110) Clostridium acetobutylicum FT 3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55) Crt, 261 aa; FT fasta scores: opt: 426 z-score: 476.6 E(): 4.4e-19; 32.4% FT identity in 259 aa overlap. Contains Pfam match to entry FT PF00378 ECH, Enoyl-CoA hydratase/isomerase family and match FT to Prosite entry PS00166 Enoyl-CoA hydratase/isomerase FT signature" FT /db_xref="GOA:Q9FBL4" FT /db_xref="HSSP:1MJ3" FT /db_xref="InterPro:IPR001753" FT /db_xref="UniProtKB/TrEMBL:Q9FBL4" FT /protein_id="CAC01345.1" FT /translation="MADTVLYEVSDGLATITLNRPEAMNALNIETKVALRDAVRSAAAD FT DAVRAVLLTAAGDRAFCVGQDLKEHIGLLAADRETGSGQTMSTVREHYNPIVRALAGAE FT KPVVAAVNGVAAGAGLGFALAADYRIVADTAAFNTSFAGVALTADSGISWTLPRVVGPG FT RAADLLLFPRSIRAQEAYELGIATRVVPAADLRAEAEKTARALAEGPTVAYAALKEAMA FT YGLTHSLSETLDKEDELQSRAGASEDHAIAVRAFVEKGKPKYLGR" FT misc_feature complement(221534..222067) FT /note="Pfam match to entry PF00378 ECH, Enoyl-CoA FT hydratase/isomerase family, score 171.20, E-value 1.8e-47" FT misc_feature complement(221723..221785) FT /note="PS00166 Enoyl-CoA hydratase/isomerase signature" FT RBS complement(222115..222119) FT CDS 222410..222634 FT /transl_table=11 FT /gene="SCO5145" FT /gene_synonym="SCP8.08" FT /product="conserved hypothetical protein" FT /note="SCP8.08, conserved hypothetical protein, len: 74 aa; FT highly similar to TR:O05312 (EMBL:Z93777) Mycobacterium FT tuberculosis hypothetical 7.8 kD protein MTCI364.23, 75 aa; FT fasta scores: opt: 323 z-score: 419.6 E(): 6.6e-16; 78.6% FT identity in 70 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9FBL3" FT /protein_id="CAC01346.1" FT /translation="MPSRAVGGDGELVSGRGTSMAAMKPRTGDGPLEVTKEGRGIVMRV FT PLEGGGRLVVELTPDEADALGDALKKVVG" FT CDS complement(222745..223269) FT /transl_table=11 FT /gene="SCO5146" FT /gene_synonym="SCP8.09c" FT /product="putative methyltransferase" FT /note="SCP8.09c, probable methyltransferase, len: 174 aa; FT similar to SW:MDMC_STRMY (EMBL:M93958) Streptomyces FT mycarofaciens O-methyltransferase (EC 2.1.1.-) MdmC, 221 FT aa; fasta scores: opt: 253 z-score: 313.8 E(): 5.2e-10; FT 31.5% identity in 178 aa overlap. Contains Pfam match to FT entry PF01596 Methyltransf_3, O-methyltransferase" FT /db_xref="GOA:Q9FBL2" FT /db_xref="InterPro:IPR002935" FT /db_xref="UniProtKB/TrEMBL:Q9FBL2" FT /protein_id="CAC01347.1" FT /translation="MTPGTGSALGLLAAAVDAKAVAEIGTGCGVSGIHLLHGMRPDGVL FT TTVDPEPEHQQFARHAFRAAGFASNRARFIPGRALDVLPRLADAGYDLVFCDGDRLEYL FT DYLAESLRLLRPGGLVAFEGVFGAGRTIDSGPQPTEVLRVRELLRAVRESQELVPSLLP FT VGDGLLCAVKR" FT misc_feature complement(222748..223269) FT /note="Pfam match to entry PF01596 Methyltransf_3, FT O-methyltransferase, score -18.50, E-value 5.8e-08" FT misc_feature 223455..223460 FT /note="DraI restriction site" FT CDS 223690..224361 FT /transl_table=11 FT /gene="SCO5147" FT /gene_synonym="SCP8.10" FT /product="putative ECF-subfamily sigma factor" FT /note="SCP8.10, probable ECF-subfamily sigma factor, len: FT 223 aa; similar to TR:O05735 (EMBL:U87308) Mycobacterium FT avium extracytoplasmic function alternative sigma factor FT SigE, 251 aa; fasta scores: opt: 852 z-score: 1013.1 E(): FT 0; 62.5% identity in 216 aa overlap and to SW:CARQ_MYXXA FT (EMBL:X71062) Myxococcus xanthus RNA polymerase sigma FT factor CarQ, 174 aa; fasta scores: opt: 285 z-score: 347.6 FT E(): 6.8e-12; 36.5% identity in 159 aa overlap. Contains FT Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor FT (ECF subfamily). Also contains a possible helix-turn-helix FT motif at residues 164..185 (+3.76 SD)" FT /db_xref="GOA:Q9FBL1" FT /db_xref="HSSP:1OR7" FT /db_xref="InterPro:IPR007627" FT /db_xref="UniProtKB/TrEMBL:Q9FBL1" FT /protein_id="CAC01348.1" FT /translation="MNDTAADHSHADGPTTGHAHTATFSSDADGQAWTPPTWEEIVSTH FT SGRVYRLAYRLTGNQHDAEDLTQEVFVRVFRSLSTYTPGTFEGWLHRITTNLFLDMVRR FT KQRIRFDALGDDAAERLPSREPTPQQLFHDAHFDADVQQALDTLAPEFRAAVVLCDIEG FT LSYEEIAATLGVKLGTVRSRIHRGRSQLRKALAHRSPKARADRRSLAAGVPALGGGGTS FT A" FT misc_feature 223840..224004 FT /note="Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 FT factor (ECF subfamily), score 95.00, E-value 1.5e-24" FT CDS 224358..225347 FT /transl_table=11 FT /gene="SCO5148" FT /gene_synonym="SCP8.11" FT /product="putative membrane protein" FT /note="SCP8.11, possible membrane protein, len: 329 aa. FT Contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9FBL0" FT /protein_id="CAC01349.1" FT /translation="MSGSRPEPEGHLAEQHLGDRLSALVDGELGHDARERVLAHVATCP FT KCKAEVDAQRRLKNVFAEAAPPAPSESFLARLQGLPGGGDSDGGGSPFSGLPGGFGASA FT ASGVFGPRRDERFEFDYVPAGSHTPVLPSATSGRGFRIHEVGRHESDRSASRGLRFAFA FT AAGAVSLAAIALGGVTLGTPDTTTEARGSGSGSNVTPLRTPGSAAATGSESQRRRTAGP FT LLGQGQRALGDLPVASTTASAPLLPGMPAPAGGDARQQAVRALTTPVTAGAAAMSPLIR FT PLEAVPPLSLSSWSAAPEVRPPGLLAAPDPAPSPYPAASPAASSSPLR" FT CDS 225838..227466 FT /transl_table=11 FT /gene="SCO5149" FT /gene_synonym="SCP8.12" FT /product="putative protease" FT /note="SCP8.12, possible protease, len: 542 aa; C-terminal FT region similar to TR:O53896 (EMBL:AL021999) Mycobacterium FT tuberculosis putative serine protease MTV044.11, 464 aa; FT fasta scores: opt: 803 z-score: 614.5 E(): 9.2e-27; 39.4% FT identity in 469 aa overlap and to TR:AAF61294 FT (EMBL:AF155705) Lactococcus lactis serine protease HtrA, FT 408 aa; fasta scores: opt: 536 z-score: 415.8 E(): 1.1e-15; FT 34.8% identity in 310 aa overlap. Contains Pfam matches to FT entries PF00089 trypsin, Trypsin and PF00595 PDZ, PDZ FT domain (Also known as DHR or GLGF)" FT /db_xref="GOA:Q9FBK9" FT /db_xref="HSSP:1LCY" FT /db_xref="InterPro:IPR001254" FT /db_xref="UniProtKB/TrEMBL:Q9FBK9" FT /protein_id="CAC01350.1" FT /translation="MEAGSRPHAGTGSVPAADGTSDAGRPKPLHEPDPYSTPPYGEPGP FT WAPAPPVQHPAATPAHGTVTAAGGALHAPVTPVTEGSHAHVPHPGASSVSPPVGAVPDP FT AFADAAPPVPPTAQEQPPAPAATPAYDTAPHDAAPPPAAPADPWGRYDPWAASAQHHDA FT AERAPKRRRGPRAKALVGGALLIALVSGGIGGGVGAYLERNGGVGTVELPQAGPEAAER FT DPDSVAGIAARALPSVVTLHVSGSEAAGTGTGFVLDGRGHILTNNHVVEPAGSGGEITV FT TFNSGDTAEAEVVGRDSGYDLAVVKVKGVTGLTPMPLGNSDNVRVGDPVVAIGAPFDLA FT GTVTSGIISAKERPITAGGEEGDGSDISYVDALQTDAPINPGNSGGPLLDARGRAIGIN FT SAIRSADSGSTESDDGQAGSIGLGFAIPINQGKRVAEELINTGKAAHPVIGITLDMNYT FT GDGARVSAKGGDGGPAVTTGGPGAKAGIKPGDVITAVDGQRVHSGEELIVKTRAHRPGD FT RLELTLQRDGKETKVSLVLGSSGDD" FT misc_feature 226513..227067 FT /note="Pfam match to entry PF00089 trypsin, Trypsin, score FT 32.00, E-value 2.6e-09" FT misc_feature 227149..227415 FT /note="Pfam match to entry PF00595 PDZ, PDZ domain (Also FT known as DHR or GLGF)., score 21.60, E-value 0.0081" FT CDS 227613..228098 FT /transl_table=11 FT /gene="SCO5150" FT /gene_synonym="SCP8.13" FT /product="putative membrane protein" FT /note="SCP8.13, putative membrane protein, len: 151 aa; FT similar to TR:O69415 (EMBL:AJ005830) Escherichia coli FT Sec-independent protein translocase TatB, 171 aa; fasta FT scores: opt: 169 z-score: 186.8 E(): 0.0061; 23.6% identity FT in 161 aa overlap. High in aspartate, glutamate and serine FT amino acid residues. Highly similar to TR:Q9EWB3 FT (EMBL:AJ292256) Streptomyces lividans twin arginine FT translocation complex component TatB 158 aa; fasta scores: FT opt: 1001 Z-score: 1020.1 E(): 3.5e-49; 97.516% identity FT in 161 aa overlap. Contains possible hydrophobic membrane FT spanning region" FT /db_xref="GOA:Q9FBK8" FT /db_xref="InterPro:IPR003998" FT /db_xref="UniProtKB/Swiss-Prot:Q9FBK8" FT /protein_id="CAC01351.1" FT /translation="MFNDIGALELVTLVVLAVLVFGPDKLPKVIQDVTRTIRKIREFSD FT SAKQDIRQELGPEFKDFEFEDLNPKTFIRKQLDNEELGLKEIRNGFDLKKEMAEVTDAV FT HGRDAESSSSGSSSGSSSAASGNGRVDMSKKPEKPEKPGKTDKPAADDRPPFDMDAT" FT CDS 228255..229001 FT /transl_table=11 FT /gene="SCO5151" FT /gene_synonym="SCP8.14" FT /product="hypothetical protein SCP8.14" FT /note="SCP8.14, unknown, len: 248 aa" FT /db_xref="UniProtKB/TrEMBL:Q9FBK7" FT /protein_id="CAC01352.1" FT /translation="MRTGRVRPKGGGPFRSDESEEASGHMETTSRAVAQAPAAEGGPQS FT PSGRRTVDGYLRAPFPWYGLDEAFTGRRWLMQIGTAADGAVEHGSIGHGDEPSVRNEHV FT AGDEQDAKEKFAVVVTVAANPDRRSADGTGLLEATSVSSAAWLAGVGLLSFTWPGQMDH FT SLRDDWLEQQTETAWVLADDLDGEDWTTLSLPVDGVPTPFHYRESEFGWVLAGSTEQGV FT HLGAYGRGMSAYGLAFAVVKDVAAYA" FT CDS complement(229076..230209) FT /transl_table=11 FT /gene="SCO5152" FT /gene_synonym="SCP8.15c" FT /product="putative ATP-binding protein" FT /note="SCP8.15c, probable ATP-binding protein, len: 371 aa; FT similar to SW:MRP_MYCTU (EMBL:Z98260) Mycobacterium FT tuberculosis Mrp protein homolog MTV006.01c, 390 aa; fasta FT scores: opt: 1650 z-score: 1730.0 E(): 0; 67.9% identity in FT 371 aa overlap and to SW:MRP_ECOLI (EMBL:U00007) FT Escherichia coli Mrp protein, 379 aa; fasta scores: opt: FT 706 z-score: 744.5 E(): 0; 35.8% identity in 363 aa FT overlap. Contains Pfam matches to entries PF01883 DUF59, FT Domain of unknown function DUF59 and PF00142 fer4_NifH, FT 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC FT family and matches to Prosite entries PS00017 FT ATP/GTP-binding site motif A (P-loop) and PS01215 Mrp FT family signature" FT /db_xref="GOA:Q9FBK6" FT /db_xref="HSSP:1HYQ" FT /db_xref="InterPro:IPR019591" FT /db_xref="UniProtKB/TrEMBL:Q9FBK6" FT /protein_id="CAC01353.1" FT /translation="MATEDAVREALATVNDPEINRPITELGMVKSVEIGADGAVAVAVY FT LTVSGCPMRDTITQRVSDAVSRVEGVTRVDVELDVMSDEQRKELATALRGGQTEREVPF FT AKPGSLTRVYAVASGKGGVGKSSVTVNLAASMAADGLKVGVVDADIYGHSVPRMLGADG FT RPTQVENMIMPPSAHGVKVISIGMFTPGNAPVVWRGPMLHRALQQFLADVYWGDLDVLL FT LDLPPGTGDIAISVAQLVPNAEILVVTTPQQAAAEVAERAGAIAVQTHQKIVGVVENMS FT GLPCPHCGEMVDVFGTGGGQTVADGLTRTTGASVPVLGAIPIDVRLREGGDEGKPVVLS FT DPDSPAGAALRSIAGKLGGRQRGLSGLSLGITPKNKF" FT misc_feature complement(229517..229567) FT /note="PS01215 Mrp family signature" FT misc_feature complement(229781..229876) FT /note="Pfam match to entry PF00142 fer4_NifH, 4Fe-4S iron FT sulfur cluster binding proteins, NifH/frxC family, score FT 16.90, E-value 0.00075" FT misc_feature complement(229832..229855) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(229949..230191) FT /note="Pfam match to entry PF01883 DUF59, Domain of unknown FT function DUF59, score 31.60, E-value 7.8e-07" FT CDS complement(230254..230850) FT /transl_table=11 FT /gene="SCO5153" FT /gene_synonym="SCP8.16c" FT /product="putative integral membrane protein" FT /note="SCP8.16c, possible integral membrane protein, len: FT 198 aa; similar to TR:O86314 (EMBL:Z98260) Mycobacterium FT tuberculosis hypothetical 20.4 kD protein MTV006.03c, 180 FT aa; fasta scores: opt: 517 z-score: 619.2 E(): 5.1e-27; FT 52.9% identity in 157 aa overlap. Contains possible FT hydrophobic membrane spanning regions" FT /db_xref="InterPro:IPR010406" FT /db_xref="UniProtKB/TrEMBL:Q9FBK5" FT /protein_id="CAC01354.1" FT /translation="MPERETTTRERATSGATASSRARARLDQPRPPRRRLLPEWDPESF FT GRLSERVARFLGTGRFIVWMTVVIILWVVWNVSAPSGLRFDEYPFIFLTLMLSLQASYA FT APLILLAQNRQDDRDRVNLEQDRKQNERSIADTEYLTREIAALRIGLGEVATRDWIRSE FT LQDLVRDLEERQNGHHPDRGVFPADRSAGRDVHDR" FT CDS complement(230843..232144) FT /transl_table=11 FT /gene="SCO5154" FT /gene_synonym="SCP8.17c" FT /product="conserved hypothetical protein" FT /note="SCP8.17c, hypothetical protein, len: 433 aa; highly FT similar to TR:O86315 (EMBL:Z98260) Mycobacterium FT tuberculosis hypothetical 47.4 kD protein MTV006.04c, 435 FT aa; fasta scores: opt: 1335 z-score: 1494.5 E(): 0; 49.9% FT identity in 425 aa overlap and C-terminal region similar to FT C-terminal region of TR:Q9X0P4 (EMBL:AE001773) Thermotoga FT maritima Mg2+ transporter MgtE, putative, 446 aa; fasta FT scores: opt: 390 z-score: 439.1 E(): 5.4e-17; 31.3% FT identity in 240 aa overlap" FT /db_xref="InterPro:IPR006668" FT /db_xref="UniProtKB/TrEMBL:Q9FBK4" FT /protein_id="CAC01355.1" FT /translation="MAAGAPRIFVSHLSGIAVFDPAGDQVGRVRDLVVMLRVGRKPPRV FT LGLVVELTTRRRIFLPMTRVTGIESGQVITTGVLNVRRFEQRPTERLVFGELLDRRVTL FT TETGEEVTVLDLSVQQLPARRDWEIDKVFVRKGRKGGAFRRNKGETLTVEWSGVSGFSV FT EEQGQGAENLLATFEQLRPADLANVLHHLSAKRRAEVAAALDDDRLADVLEELPEDDQI FT EILGKLKEERAADVLEAMDPDDAADLLGELPEADKERLLSLMQPEDAADMRRLMAYEEH FT TAGGLMTTEPIVLRPDATVADALARIRNPDLSPAHAAQVYVCRPPEETPTGKYLGTVHF FT QRLLRDPPYTLVGSILDDDLQPLEPDAALPVVAGFFAAYDMVAAPVVDDSGALLGAVTV FT DDVLDHMLPDDWRETEYHLDETTGTTGEVGADGA" FT RBS complement(232153..232160) FT CDS 232439..233170 FT /transl_table=11 FT /gene="SCO5155" FT /gene_synonym="SCP8.18" FT /product="putative lipoprotein" FT /note="SCP8.18, possible lipoprotein, len: 243 aa; similar FT to TR:CAB76294 (EMBL:AL158057) Streptomyces coelicolor FT putative lipoprotein SC1G8.21c, 249 aa; fasta scores: opt: FT 238 z-score: 275.6 E(): 7e-08; 29.3% identity in 249 aa FT overlap. Contains possible N-terminal region signal peptide FT sequence and correctly situated match to Prosite entry FT PS00013 Prokaryotic membrane lipoprotein lipid attachment FT site" FT /db_xref="UniProtKB/TrEMBL:Q9FBK3" FT /protein_id="CAC01356.1" FT /translation="MTPRRRIRRAALLGAVCALAVTGAGLTGCSSEDPDAGTNGLGKLS FT ADKIQAKAGTAAQAARTVRLHGSVEAAGSTYTLDMRLKADGGTGSVAAEGTTFGLLRVG FT EQLFLKADAGFWSHDGGDAKAADKLAGKYVKVPQSDPVYKKFSGFTDKDVLLGGLLTLH FT GTVKTDGRHEQAGVRTIRITGDDGAGGSLDVSLEGTPYPLRLVRAGSAGTIGFSDWNKD FT FALEQPAKDDTLDYGKQLPSS" FT misc_feature 232493..232525 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(233185..233697) FT /transl_table=11 FT /gene="SCO5156" FT /gene_synonym="SCP8.19c" FT /product="hypothetical protein SCP8.19c" FT /note="SCP8.19c, unknown, len: 170 aa" FT /db_xref="UniProtKB/TrEMBL:Q9FBK2" FT /protein_id="CAC01357.1" FT /translation="MTSELLDQALVEEATKKSGLVWVKGPGVPARALWHVWHDGAACVV FT GDGPGEQPLPGLADGAAAEVTVRSKDKGGRLVSWAARVVELPSGSEAWQAAVGDLKGKR FT LNAPDGEAMTGRWARECRVLRLEPTGTTAPLPDASLAEAPLPSPATTRQPVPAGLPRLL FT LKRRKRR" FT CDS complement(233731..234846) FT /transl_table=11 FT /gene="SCO5157" FT /gene_synonym="SCP8.20c" FT /product="putative metal-transport protein" FT /note="SCP8.20c, probable metal-transport protein, len: 371 FT aa; similar to TR:O50455 (EMBL:AL021006) Mycobacterium FT tuberculosis putative magnesium and cobalt transport FT protein MTV006.11c, 366 aa; fasta scores: opt: 1137 FT z-score: 1293.8 E(): 0; 47.8% identity in 370 aa overlap FT and to SW:CORA_ECOLI (EMBL:L11042) Escherichia coli FT magnesium and cobalt transport protein CorA, 316 aa; fasta FT scores: opt: 211 z-score: 245.7 E(): 3.2e-06; 23.2% FT identity in 306 aa overlap. Contains Pfam match to entry FT PF01544 CorA, CorA-like Mg2+ transporter protein and FT possible hydrophobic membrane spanning region at C-terminal FT domain" FT /db_xref="GOA:Q9FBK1" FT /db_xref="InterPro:IPR002523" FT /db_xref="UniProtKB/TrEMBL:Q9FBK1" FT /protein_id="CAC01358.1" FT /translation="MSMIRDLRAAVRPSRVSLRKDGGAYDTTRDPATASAVVDCAVYHD FT GTRVETDVPLTPHTAMRQVRRDGGFVWIGLHEPTEDEFAGIAREFGLHPLAVEDAVQAH FT QRPKLERYDDSLFTVFKTVHYVDHDQLTANSEVVETGEVMCFTGRDFFITVRHGGQGSL FT RALRRRLQEDPELLLKGPSAVLHAIADHVVDGYIAVADAVQDDIDEVETEVFSPGRKGS FT PRGTDAGRIYQLKREVLEFKRAVAPLLRPMQLLSERPMRLVDPEIQKYFRDVADHVARV FT QEQVIGFDELLNSILQANLAQASVAQNEDMRKITSWAAIIAVPTMVCGVYGMNFDYMPE FT THWKFGYPLVLSVTVCICLGIHRTLKRNGWL" FT misc_feature complement(233734..234654) FT /note="Pfam match to entry PF01544 CorA, CorA-like Mg2+ FT transporter protein, score 299.50, E-value 4.1e-86" FT RBS complement(234853..234858) FT CDS 235370..235966 FT /transl_table=11 FT /gene="SCO5158" FT /gene_synonym="SCP8.21" FT /product="hypothetical protein SCP8.21" FT /note="SCP8.21, unknown, len: 198 aa" FT /db_xref="UniProtKB/TrEMBL:Q9FBK0" FT /protein_id="CAC01359.1" FT /translation="MADVLPLVEARLRSALGEPDARAAVTFLGTDRIEVLRFPAAGQEG FT DVVRYATLGMSAQPMADPTAVLADPVKGPRAELVLSVRSGAADTDKVLRPLAVLAASPQ FT VEGVIVAPGASLDVGEPLWPGAPFTSVLVAEPGGLVEDLELDAPLDPVRFLPLLPMTPN FT EAAWKRVHGAPALQERWLNHGTDLRDPSRRSVPLD" FT CDS complement(236015..237238) FT /transl_table=11 FT /gene="SCO5159" FT /gene_synonym="SCP8.22c" FT /product="putative integral membrane transport protein" FT /note="SCP8.22c, possible integral membrane transport FT protein, len: 407 aa; similar to TR:CAB76344 FT (EMBL:AL158061) Streptomyces coelicolor putative FT multidrug-efflux transporter protein SC6D11.21, 577 aa; FT fasta scores: opt: 1286 z-score: 1436.2 E(): 0; 51.1% FT identity in 393 aa overlap and to SW:BMR1_BACSU FT (EMBL:M33768) Bacillus subtilis multidrug resistance FT protein 1 Bmr1, 389 aa; fasta scores: opt: 262 z-score: FT 298.0 E(): 3.9e-09; 22.9% identity in 375 aa overlap. FT Contains Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter and possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q9FBJ9" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9FBJ9" FT /protein_id="CAC01360.1" FT /translation="MDPFDVGAGGILRQPKAVWATAGASVVAFMGIGLVDPILPSIAKG FT LDASAGQVSLLFTSYFLITALAMLVTGFVSSRIGGRKTLLLGLAFVVVFAGLAGTSDTV FT GQLVGYRAGWGLGNALFVSTALAVIVGAAAGGSAAAILLYESALGLGMACGPLLGALLG FT DASWRYPFFGTAFLMAIGFLCITVFLKEQPRPARKTSLLDPIRALGHGGLASAAVSAFF FT YNYTFFTVLAFTPFVLNMTPYKSGAVFFAWGVLLAVFSVLVAPRMQRRFGSLKVLGGSL FT VLLAADVLVLGYGNHTAAIVCTILSGAFIGVNNTVYTELALGVSDAPRPVASAGYNFVR FT WFAAAAAPYFAPKIEEWTDVHVPFVVAAVTALLGAVVVVVRRRALTHDAEELEPKHASE FT DSVTVFAN" FT misc_feature complement(236060..237172) FT /note="Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter, score -93.70, E-value 0.0016" FT RBS complement(237246..237249) FT misc_feature 237319..237324 FT /note="AseI restriction site" FT /note="Cleavage site for AseI restriction endonuclease FT AT*TAAT." FT misc_feature complement(237319..237324) FT /note="Cleavage site for AseI restriction endonuclease FT AT*TAAT." FT CDS 237430..238080 FT /transl_table=11 FT /gene="SCO5160" FT /gene_synonym="SCP8.23" FT /product="hypothetical protein SCP8.23" FT /note="SCP8.23, unknown, len: 216 aa" FT /db_xref="UniProtKB/TrEMBL:Q9FBJ8" FT /protein_id="CAC01361.1" FT /translation="MRGEPSCPKCGGRVRAPGLFADSWQCDLHGTVHPVQPVLPPSVEA FT LGVVVHRTQVPLWMPWPLPVGWLFTGVACAGDDRSGGRATAVACSGPGPLGGIGELILV FT AEELGVGLGARYAGLDGPDPGPYLDVEKPPQVKVLAAGRPTPLWHVSGGPVDRAVFAGE FT ALGMWLWAVVWPERSGLLMYEELVLTDLRDAGAEVDLVPCGALSPRLIEPTAP" FT RBS 238297..238300 FT CDS 238309..239166 FT /transl_table=11 FT /gene="SCO5161" FT /gene_synonym="SCP8.24" FT /product="conserved hypothetical protein" FT /note="SCP8.24, hypothetical protein, len: 285 aa; similar FT to SW:TRPH_ECOLI (EMBL:AE000224) Escherichia coli TrpH FT protein, 293 aa; fasta scores: opt: 376 z-score: 429.3 E(): FT 1.9e-16; 30.6% identity in 248 aa overlap. Contains Pfam FT match to entry PF02231 PHP_N, PHP domain N-terminal region" FT /db_xref="GOA:Q9FBJ7" FT /db_xref="InterPro:IPR003141" FT /db_xref="UniProtKB/TrEMBL:Q9FBJ7" FT /protein_id="CAC01362.1" FT /translation="MRIDLHTHSTASDGTDTPAQLVRKAAATGLDVVALTDHDTTRGHA FT EAVAALPEGLTLVTGAELSCRLDGVSMHMLAYLFDPEEPALLAERELVRDDRVPRARAM FT VAKLNELGVPVTWEQVARIAGGGSVGRPHVASALVELGVVPTVNDAFTRDWLADGGRAH FT VGKHETDPFEALRLIKGAGGVAVFAHPAAAKRGRTVSEAAIADLAAAGLDGIEVDHMDH FT DTQTRARLRGAAKELGLLVTGSSDYHGSRKTCVLGEYTTDPEVYGEITRRAFGAFPVPG FT AGGA" FT misc_feature 238315..238503 FT /note="Pfam match to entry PF02231 PHP_N, PHP domain FT N-terminal region, score 74.90, E-value 1.7e-18" FT CDS 239220..239825 FT /transl_table=11 FT /gene="SCO5162" FT /gene_synonym="SCP8.25" FT /product="putative integral membrane protein" FT /note="SCP8.25, possible integral membrane protein, len: FT 201 aa; similar to SW:YCHE_ECOLI (EMBL:AE000222) FT Escherichia coli hypothetical 23.5 kD protein in AdhE-OppA FT intergenic region YchE, 215 aa; fasta scores: opt: 406 FT z-score: 496.2 E(): 3.6e-20; 30.0% identity in 207 aa FT overlap. Contains Pfam match to entry PF01914 UPF0056, FT Uncharacterized protein family UPF0056 and possible FT hydrophobic membrane spanning regions" FT /db_xref="InterPro:IPR002771" FT /db_xref="UniProtKB/TrEMBL:Q9FBJ6" FT /protein_id="CAC01363.1" FT /translation="MFDVAVFGSLFLTLFVIMDPPGITPIFLALTSGRPGKVQKRMALQ FT AVCVAGGVITVFGLLGHQILDYLHVSVPALMIAGGLLLLLIALDLLTGKTDEPKQTKDV FT NVALVPLGMPLLAGPGAIVSVILAVQKADSVTTQVSVWAAILAIHVVLWLVMRYSLLII FT RVIKDGGVVLVTRLAGMMLSAIAVQQIINGVTQVIQGA" FT misc_feature 239229..239813 FT /note="Pfam match to entry PF01914 UPF0056, Uncharacterized FT protein family UPF0056, score 165.40, E-value 9.6e-46" FT CDS complement(239892..240044) FT /transl_table=11 FT /gene="SCO5163" FT /gene_synonym="SCP8.26c" FT /product="hypothetical protein SCP8.26c" FT /note="SCP8.26c, unknown, len: 50 aa. Highly hydrophilic" FT /db_xref="UniProtKB/TrEMBL:Q9FBJ5" FT /protein_id="CAC01364.1" FT /translation="MRFEVMRLDDVDGTPVDTTVVDAASVNRIVQQAAAIGQRLWIRPA FT DTSAL" FT RBS complement(240050..240053) FT CDS 240280..241185 FT /transl_table=11 FT /gene="SCO5164" FT /gene_synonym="SCP8.27" FT /product="hypothetical protein" FT /note="SCP8.27, hypothetical protein, len: 300 aa; similar FT to N-terminal region of TR:Q9S2S7 (EMBL:AL096884) FT Streptomyces coelicolor hypothetical 44.0 kD protein FT SC4G6.31c, 403 aa; fasta scores: opt: 423 z-score: 494.8 FT E(): 4.3e-20; 36.5% identity in 230 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9FBJ4" FT /protein_id="CAC01365.1" FT /translation="MEAMNDDLAPLNARIDRTNELLQRMLAEVAKTPSTHAIFVDAGYL FT YAAAGRLVAGTEDRRAFDLDAEGLIEALIDRARNIFADSRLLRVYWYDGARRRIHTAEQ FT QSIAELPDVKVRLGNLNANNQQKGVDSLIRTDLESLARHRAISDAALLGGDEDLVSAVE FT AAQGFGARVHLWGIEAPEGRNQAEPLLWEVDSQRTLDLDFFKPYVSRRTAPAAEATGLT FT RPAREDVRFVGAQIAAKWLASRGRESLVELLPGHPYLPGSVDQDLLVEAEGLLQYSLRG FT QADLRRALRDGFWEHLRAQY" FT CDS complement(241293..242189) FT /transl_table=11 FT /gene="SCO5165" FT /gene_synonym="SCP8.28c" FT /product="putative hydrolase" FT /note="SCP8.28c, possible hydrolase, len: 298 aa; similar FT to TR:Q9RL59 (EMBL:AL121596) Streptomyces coelicolor FT putative hydrolase SCF51A.05, 278 aa; fasta scores: opt: FT 217 z-score: 249.2 E(): 2e-06; 27.0% identity in 267 aa FT overlap and to SW:THCF_RHOER (EMBL:U95170) Rhodococcus FT erythropolis non-heme haloperoxidase (EC 1.11.1.-) ThcF, FT 274 aa; fasta scores: opt: 185 z-score: 213.7 E(): FT 0.00019l; 29.0% identity in 241 aa overlap. Contains Pfam FT match to entry PF00561 abhydrolase, alpha/beta hydrolase FT fold and match to Prosite entry PS00120 Lipases, serine FT active site" FT /db_xref="GOA:Q9FBJ3" FT /db_xref="InterPro:IPR000073" FT /db_xref="UniProtKB/TrEMBL:Q9FBJ3" FT /protein_id="CAC01366.1" FT /translation="MSRNAAFSPPPSARAYRLRTARGEFAVVDSPAAAGVAPRGVVMML FT PGFTGSKEDFTLLHRPLGARGYRTVAVDGRGQYESDGPEHDESAYARPELARDVLAQAA FT ALGTRVHLVGHSLGGQIARAAVLLDPAPFLSLTLMSSGPARISESQRQRVKLLRDALDT FT MTMAEVWEVMQAMGPPEEAGAPAPAHGPEDRVRLRDRWLGTRPAQLLATGGQLCTEPDR FT VAELAAVPLPFHVLSGTYDDTWPVPLLDEMALRLDARRTVVAGAEHSPNTDQPLPTARA FT LADFWDDHPVPPRPYVR" FT misc_feature complement(241332..241991) FT /note="Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold, score 36.00, E-value 8.4e-07" FT misc_feature complement(241833..241862) FT /note="PS00120 Lipases, serine active site" FT CDS complement(242300..244939) FT /transl_table=11 FT /gene="SCO5166" FT /gene_synonym="SCP8.29c" FT /product="putative helicase" FT /note="SCP8.29c, possible helicase, len: 879 aa; N-terminal FT domain similar to SW:RHLE_ECOLI (EMBL:L02123) Escherichia FT coli putative ATP-dependent RNA helicase RhlE, 454 aa; FT fasta scores: opt: 884 z-score: 704.8 E(): 8.6e-32; 37.2% FT identity in 444 aa overlap. Contains Pfam matches to FT entries PF00270 DEAD, DEAD/DEAH box helicase and PF00271 FT helicase_C, Helicases conserved C-terminal domain and FT matches to Prosite entries PS00017 ATP/GTP-binding site FT motif A (P-loop) and PS00039 DEAD-box subfamily FT ATP-dependent helicases signature. Also contains three sets FT of different repeats: 10x RU1: RRTRK, 4x RU2:AAAKAEAAA and FT 4x RU3:AAEPA" FT /db_xref="GOA:Q9FBJ2" FT /db_xref="HSSP:1HV8" FT /db_xref="InterPro:IPR014021" FT /db_xref="UniProtKB/TrEMBL:Q9FBJ2" FT /protein_id="CAC01367.1" FT /translation="MTLPVALSGKDVIGQAKTGTGKTLGFGLPLLERVTVPADVEAGRA FT APESLTDAPQALVVVPTRELCQQVTNDLLTAGKVRNVRVLAIYGGRAYEPQVEALKQGV FT DVIVGTPGRLLDLAGQNKLSLKHIKSLVLDEADEMLDLGFLPDVEKIINMLPARRQTML FT FSATMPGAVIGLARRYMSQPTHISATSPDDEGATVANTKQFIYRAHNMDKPEMVARILQ FT ADGRGLAMVFCRTKRTAADLADQLKQRGFASGAVHGDLGQGAREQALRAFRNGKVDVLV FT CTDVAARGIDVEGVTHVINYQSPEEEKTYLHRIGRTGRAGAKGTAITLVDWDDIPRWQL FT INKALDLGFNDPPETYSTSPHLYTDLGIAEGTKGVLPRSERTRAGLDAEELEDLGEPGG FT RGGRGRGDRGDRGGRGGRDDSRSGDRERDRSSRTTPRRRRRMRGGAPVDAEASVAPAAE FT TVTVTDGAAGATDAGTDTDKAPRTLRRRRRTRSGEPSRRQETAATLGTDGPAAQAAEDA FT ALAPSEAPVVETVAAEPVAAPEAVEAPAKPRRRTRTRKAAETPAAPLETAPTAAPTATE FT ESIVAPAVVETPTVEAPAEKPRRRTRKATAAEATVETAEGAAEPAPEPAETKPRRRTRK FT AAEPAAQAPDAEAEAEAKPRRTRKTTATKTAAAKAEAAADTAEAAEAKPKARRTRKAAE FT PAVQAAPEGEAEAEAKPRRTRKTTATKTAAAKAEAAADTAEAAEAKPKARRTRKAAEPA FT VQAAPEGEAETEAKPRRTRKTTATKTAAAKAEAAAKAEAAADTAEAAEAKPKARRARKT FT AAAVEATAEIPAQASQEPEAAPRRRTRKAAVAVEAPAAGADTAEAKPKARRTRKTAAAA FT QPAEAGES" FT repeat_region complement(242342..242356) FT /note="10x conserved repeat unit translated in SCP8.29c FT (RU1)" FT repeat_region complement(242420..242434) FT /note="RU1" FT repeat_region complement(242507..242521) FT /note="RU1" FT repeat_region complement(242558..242584) FT /note="4x conserved repeat unit translated in SCP8.29c FT (RU2)" FT repeat_region complement(242576..242602) FT /note="RU2" FT repeat_region complement(242621..242635) FT /note="RU1" FT repeat_region complement(242681..242695) FT /note="4x conserved repeat unit translated in SCP8.29c FT (RU3)" FT repeat_region complement(242696..242710) FT /note="RU1" FT repeat_region complement(242747..242773) FT /note="RU2" FT repeat_region complement(242792..242806) FT /note="RU1" FT repeat_region complement(242852..242866) FT /note="RU3" FT repeat_region complement(242867..242881) FT /note="RU1" FT repeat_region complement(242917..242944) FT /note="RU2" FT repeat_region complement(242963..242977) FT /note="RU1" FT repeat_region complement(243020..243034) FT /note="RU3" FT repeat_region complement(243035..243049) FT /note="RU1" FT repeat_region complement(243077..243091) FT /note="RU3" FT repeat_region complement(243131..243145) FT /note="RU1" FT misc_feature complement(243977..244222) FT /note="Pfam match to entry PF00271 helicase_C, Helicases FT conserved C-terminal domain, score 123.30, E-value 4.6e-33" FT misc_feature complement(244328..244936) FT /note="Pfam match to entry PF00270 DEAD, DEAD/DEAH box FT helicase, score 172.60, E-value 1.2e-53" FT misc_feature complement(244520..244546) FT /note="PS00039 DEAD-box subfamily ATP-dependent helicases FT signature" FT misc_feature complement(244871..244894) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(244940..244946) FT CDS 245432..246214 FT /transl_table=11 FT /gene="SCO5167" FT /gene_synonym="SCP8.30" FT /product="conserved hypothetical protein" FT /note="SCP8.30, conserved hypothetical protein, len: 260 FT aa; similar to TR:O05856 (EMBL:Z95120) Mycobacterium FT tuberculosis hypothetical 25.1 kD protein MTCY07D11.16, 231 FT aa; fasta scores: opt: 599 z-score: 647.2 E(): 1.4e-28; FT 42.5% identity in 233 aa overlap. Contains 4x degenerate FT repeat:T(G/A)G" FT /db_xref="UniProtKB/TrEMBL:Q9FBJ1" FT /protein_id="CAC01368.1" FT /translation="MTSSDKPGTAADAPAETAGTAGTAGTGGATPVAARDWAAAAADPQ FT YRAAVVDLLGALAYGELAAFERLAEDAKLAPTLADKAELAKMASAEFHHFERLRDRLAE FT IGEEPTGAMEPFVAAYDGFHKQTDPSDWLEGLVKAYVGDSIASDFYREVAARLDTDTRE FT LVLAVLDDTGHAGFAVEKVRAAIDADPRVGGRLALWARRLMGEALSQSQRVVADRDALS FT TMLVGGVADGFDLAEVGKMFSRITEAHTKRMAALGLAA" FT repeat_region 245480..245515 FT /note="4x degenerate repeat translated in SCP8.30" FT CDS complement(246330..246599) FT /transl_table=11 FT /gene="SCO5168" FT /gene_synonym="SCP8.31c" FT /product="putative integral membrane protein" FT /note="SCP8.31c, possible integral membrane protein, len: FT 89 aa. Contains possible hydrophobic membrane spanning FT regions. Also high content in alanine and leucine amino FT acid residues" FT /db_xref="UniProtKB/TrEMBL:Q9FBJ0" FT /protein_id="CAC01369.1" FT /translation="MFLEALSAALLGLALAWAAAHRLPHRLPAPLLVLPTGVAGALFGA FT FVTHTALGAGGLVPVLLGSATVSAASLSLLLRPAGRLRRSSATA" FT RBS complement(246609..246613) FT CDS complement(246843..247127) FT /transl_table=11 FT /gene="SCO5169" FT /gene_synonym="SCP8.32c" FT /product="putative ATP-binding protein" FT /note="SCP8.32c, possible ATP-binding protein, len: 94 aa. FT Contains match to Prosite entry PS00017 ATP/GTP-binding FT site motif A (P-loop)" FT /db_xref="GOA:Q9FBI9" FT /db_xref="UniProtKB/TrEMBL:Q9FBI9" FT /protein_id="CAC01370.1" FT /translation="MCWYGAEDRALTDRRRDIAVEVKIGVQHAPREIVLESGQSADEVE FT |