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EBI DbfetchID AL939121; SV 1; linear; genomic DNA; STD; PRO; 292100 BP. XX AC AL939121; AL031317; AL160431; AL161691; AL161755; AL161803; AL353872; AC AL356832; AL389898; AL450450; AL451182; AL589164; XX DT 25-OCT-2002 (Rel. 73, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 4) XX DE Streptomyces coelicolor A3(2) complete genome; segment 18/29 XX KW . XX OS Streptomyces coelicolor OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Streptomycineae; Streptomycetaceae; Streptomyces. XX RN [1] RP 1-292100 RA Bentley S.D.; RT ; RL Submitted (09-MAY-2002) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Streptomyces sequencing team, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL sdb@sanger.ac.uk XX RN [2] RX DOI; 10.1038/417141a RX PUBMED; 12000953. RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L., RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H., RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E., RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D., RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.; RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor RT A3(2)"; RL Nature 417(6885):141-147(2002). XX DR EMBL-CON; AL645882. DR RFAM; RF00379; ydaO-yuaA. XX FH Key Location/Qualifiers FH FT source 1..292100 FT /organism="Streptomyces coelicolor" FT /strain="A3(2)" FT /mol_type="genomic DNA" FT /db_xref="taxon:1902" FT RBS 97..103 FT CDS 111..3596 FT /transl_table=11 FT /gene="SCO4654" FT /gene_synonym="rpoB" FT /gene_synonym="SCD82.26" FT /product="DNA-directed RNA polymerase beta chain" FT /note="SCD82.26, rpoB, DNA-directed RNA polymerase beta FT chain, len: 1161 aa; highly similar to SW:RPOB_MYCTU FT (EMBL:L27989) Mycobacterium tuberculosis DNA-directed RNA FT polymerase beta chain (EC 2.7.7.6) RpoB, 1178aa; fasta FT scores: opt: 5849 z-score: 6361.5 E(): 0; 75.7% identity in FT 1169 aa overlap. Contains Pfam match to entry PF00562 FT RNA_pol_B, RNA polymerase beta subunit and match ot Prosite FT entry PS01166 RNA polymerases beta chain signature" FT /db_xref="GOA:Q9L0L0" FT /db_xref="HSSP:1HQM" FT /db_xref="InterPro:IPR007641" FT /db_xref="UniProtKB/Swiss-Prot:Q9L0L0" FT /protein_id="CAB77428.1" FT /translation="MAASRNASTANTNNAASTAPLRISFAKIKEPLEVPNLLALQTESF FT DWLLGNDAWKARVESALESGQDVPTKSGLEEIFEEISPIEDFSGSMSLTFRDHRFEPPK FT NSIDECKDRDFTYAAPLFVTAEFTNNETGEIKSQTVFMGDFPLMTNKGTFVINGTERVV FT VSQLVRSPGVYFDSSIDKTSDKDIFSAKIIPSRGAWLEMEIDKRDMVGVRIDRKRKQSV FT TVLLKALGWTTEQILEEFGEYESMRATLEKDHTQGQDDALLDIYRKLRPGEPPTREAAQ FT TLLENLYFNPKRYDLAKVGRYKVNKKLGADEPLDAGVLTTDDVIATIKYLVKLHAGETE FT TVGESGREIVVETDDIDHFGNRRIRNVGELIQNQVRTGLARMERVVRERMTTQDVEAIT FT PQTLINIRPVVASIKEFFGTSQLSQFMDQNNPLSGLTHKRRLNALGPGGLSRERAGFEV FT RDVHPSHYGRMCPIETPEGPNIGLIGSLASYGRINPFGFIETPYRKVVEGQVTDDVDYL FT TADEEDRFVIAQANAALGDDMRFAEARVLVRRRGGEVDYVPGDDVDYMDVSPRQMVSVA FT TAMIPFLEHDDANRALMGANMMRQAVPLIKSESPLVGTGMEYRSAADAGDVVKAEKAGV FT VQEVSADYITTTNDDGTYITYRLAKFSRSNQGTSVNQKVIVAEGDRIIEGQVLADGPAT FT ENGEMALGKNLLVAFMPWEGHNYEDAIILSQRLVQDDVLSSIHIEEHEVDARDTKLGPE FT EITRDIPNVSEEVLADLDERGIIRIGAEVVAGDILVGKVTPKGETELTPEERLLRAIFG FT EKAREVRDTSLKVPHGEIGKVIGVRVFDREEGDELPPGVNQLVRVYVAQKRKITDGDKL FT AGRHGNKGVISKINPIEDMPFLEDGTPVDIILNPLAVPSRMNPGQVLEIHLGWLASRGW FT DVSGLAEEWAQRLQVIGADKVEPGTNVATPVFDGAREDELAGLLQHTIPNRDGERMVLP FT SGKARLFDGRSGEPFPEPISVGYMYILKLHHLVDDKLHARSTGPYSMITQQPLGGKAQF FT GGQRFGEMEVWALEAYGAAYALQELLTIKSDDVTGRVKVYEAIVKGENIPEPGIPESFK FT VLIKEMQSLCLNVEVLSSDGMSIEMRDTDEDVFRAAEELGIDLSRREPSSVEEV" FT misc_feature 411..3356 FT /note="Pfam match to entry PF00562 RNA_pol_B, RNA FT polymerase beta subunit, score 1264.40, E-value 0" FT misc_feature 2712..2750 FT /note="PS01166 RNA polymerases beta chain signature" FT RBS 3676..3682 FT CDS 3694..7593 FT /transl_table=11 FT /gene="SCO4655" FT /gene_synonym="rpoC" FT /gene_synonym="SCD82.27" FT /gene_synonym="SCD40A.01" FT /product="DNA-directed RNA polymerase beta' chain FT (fragment)" FT /note="SCD82.27, rpoC, DNA-directed RNA polymerase beta' FT chain (fragment), len: >1058 aa; highly similar to FT SW:RPOC_MYCTU (EMBL:L27989) Mycobacterium tuberculosis FT DNA-directed RNA polymerase beta' chain (EC 2.7.7.6) RpoC, FT 1316aa; fasta scores: opt: 5139 z-score: 5536.5 E(): 0; FT 72.9% identity in 1067 aa overlap. Contains Pfam match to FT entry PF00623 RNA_pol_A, RNA polymerase alpha subunit. FT Contains also possible coiled-coil region aprox. at FT residues 168..220" FT /note="SCD40A.01, rpoC, DNA-directed RNA polymerase beta' FT chain (fragment), len: >279 aa; similar to C-terminal FT region of SW:RPOC_BACSU (EMBL:L43593) Bacillus subtilis FT DNA-directed RNA polymerase beta' chain (EC 2.7.7.6) RpoC, FT 1199 aa; fasta scores: opt:801 z-score: 911.4 E(): 0; 53.0% FT identity in 247 aa overlap" FT /db_xref="GOA:Q8CJT1" FT /db_xref="HSSP:1HQM" FT /db_xref="InterPro:IPR012754" FT /db_xref="UniProtKB/Swiss-Prot:Q8CJT1" FT /protein_id="CAD55212.1" FT /translation="MLDVNFFDELRIGLATADDIRQWSHGEVKKPETINYRTLKPEKDG FT LFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHI FT WYFKGVPSRLGYLLDLAPKDLEKVIYFAAYMITFVDEERRTRDLPSLEAHVSVERQQIE FT QRRDSDLEARAKKLETDLAELEAEGAKADVRRKVREGAEREMKQLRDRAQREIDRLDEV FT WNRFKNLKVQDLEGDELLYRELRDRFGTYFDGSMGAAALQKRLESFDLDEEAERLREII FT RTGKGQKKTRALKRLKVVSAFLQTSNSPKGMVLDCVPVIPPDLRPMVQLDGGRFATSDL FT NDLYRRVINRNNRLKRLLDLGAPEIIVNNEKRMLQEAVDALFDNGRRGRPVTGPGNRPL FT KSLSDMLKGKQGRFRQNLLGKRVDYSARSVIVVGPQLKLHQCGLPKAMALELFKPFVMK FT RLVDLNHAQNIKSAKRMVERGRTVVYDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPQLV FT EGKAIQIHPLVCTAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILKPADGRPVTM FT PTQDMVLGLFFLTTDSEGRSPKGEGRAFGSSAEAIMAFDAGDLTLQAKIDIRFPVGTIP FT PRGFEPPAREEGEPEWQQGDTFTLKTTLGRALFNELLPEDYPFVDYEVGKKQLSEIVND FT LAERYPKVIVAATLDNLKAAGFFWATRSGVTVAISDIVVPDAKKEIVKGYEGQDEKVQK FT QYERGLITKEERTQELIAIWTKATNEVAEAMNDNFPKTNPVSMMVNSGARGNMMQMRQI FT AGMRGLVSNAKNETIPRPIKASFREGLSVLEYFISTHGARKGLADTALRTADSGYLTRR FT LVDVSQDVIIREEDCGTERGLKLPIATRDADGTLRKAEDVETSVYARMLAEDVVIDGKV FT IAPANVDLGDVLIDALVAHGVEEVKTRSILTCESQVGTCAMCYGRSLATGKLVDIGEAV FT GIIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVVELFEARTPKGVAPISEASGRV FT RIEETEKTKKIVVTPDDGSDETAFPISKRARLLVGEGDHVEVGQKLTVGATNPHDVLRI FT LGQRAVQVHLVGEVQKVYNSQGVSIHDKHIEIIIRQMLRRVTIIESGDAELLPGELVER FT TKFETENRRVVQEGGHPASGRPQLMGITKASLATESWLSAASFQETTRVLTDAAINAKS FT DSLIGLKENVIIGKLIPAGTGLSRYRNIRVEPTEEAKAAMYSAVGYDDIDYSPFGTGSG FT QAVPLEDYDYGPYNQ" FT misc_feature 4621..6402 FT /note="Pfam match to entry PF00623 RNA_pol_A, RNA FT polymerase alpha subunit, score 859.20, E-value 1.3e-254" FT CDS 7703..8290 FT /transl_table=11 FT /gene="SCO4656" FT /gene_synonym="SCD40A.02" FT /product="putative integral membrane protein" FT /note="SCD40A.02, possible integral membrane protein, len: FT 195 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9L0K7" FT /protein_id="CAB81847.1" FT /translation="MSDDKPVPNNLLVSGVAVLLLNLLIWGGAGSFAAFLWDFAGRASN FT CGPRIGVPCPEGTGYGLAGPWVAALAALALLAHLWREGVRGPMPAAAVPFVLGAVLGAR FT FLWSAVFFADDSESRIVMAVVGVLLGGLPGALYGRWLFGRWGAALLLWGVRLDRGGPVP FT ASGPAQEGARNILLALSLTGAVLGCAGGAALV" FT CDS complement(8307..9611) FT /transl_table=11 FT /gene="SCO4657" FT /gene_synonym="SCD40A.03c" FT /product="putative integral membrane protein" FT /note="SCD40A.03c, possible integral membrane protein, len: FT 434 aa; similar to TR:Q9EWX4 (EMBL:AL445403) Streptomyces FT coelicolor putative integral membrane protein 2SCI34.05, FT 396 aa; fasta scores: opt: 678 Z-score: 732.5 E(): 3.6e-33; FT 37.923% identity in 414 aa overlap. Contains possible FT hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9L0K6" FT /protein_id="CAB81848.1" FT /translation="MTAMDTAADDTVTDGPDGTGERPAGGEGAARSWRSRLPALPPGAR FT PYLAPLALYGVTKLVGLGVFASLLTHAGDFRGKNPRFGGGAHWWDVLATWDGWWYLQVA FT EHGYSPALVRLDSDGLFTVQQNSVAFFPLYPALIRMVSESTGLGLYGSGILVSVVSSFV FT AAAGIYAVISLLAGARAGTVAAGLWAVAPGAGVEWAVYSESLFVAIAAWTCYAVMKGRW FT VTAGLLAFTAGLNRPTSAVLIGAVGLAALVTLARPASRREHGVRGPVYAMLVAPLGLLS FT YIAWVGWSTGEATAYFTLQREGWAHFFDYGAYTWDVLRNLAVGRGDYPFAFSTPDLLSL FT QLVLALPFLIALMLRRRPPLVLVAYTLATIVTVLGTQQMFGNTMRYLLPAFPLLLAPAA FT ALSRLKLPSLIVFFTTASIASGWYAHYVIFELGVP" FT RBS complement(9615..9618) FT RBS 9694..9698 FT CDS 9703..10740 FT /transl_table=11 FT /gene="SCO4658" FT /gene_synonym="SCD40A.04" FT /product="putative glucosyltransferase" FT /note="SCD40A.04, possible glucosyltransferase, len: 345 FT aa; similar to TR:O21943 (EMBL:AF021347) Bacteriophage SfII FT bactoprenol glucosyl transferase Bgt, 309 aa; fasta scores: FT opt: 728 z-score: 801.5 E(): 0; 39.0% identity in 305 aa FT overlap and to SW:YJ43_SYNY3 (EMBL:D90915) Synechocystis FT sp. hypothetical 37.6 kD protein Slr1943, 331 aa; fasta FT scores: opt: 846 z-score: 929.7 E(): 0; 42.4% identity in FT 309 aa overlap. Contains Pfam match to entry PF00535 FT Glycos_transf_2, Glycosyl transferases and possible FT hydrophobic membrane spanning regions in C-terminal domain" FT /db_xref="GOA:Q9L0K5" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q9L0K5" FT /protein_id="CAB81849.1" FT /translation="MPEGRDAERHAPVVLSVVIPMFNEEDVLPALVTRLRPVLTELGVP FT HEVVAVDDGSGDRTAELLDAFRLGWPELRVVALRRNSGHQAALTAGLDRARGAYVVSLD FT ADLQDPPEKIPDMLALARAEGLDIVYGVRADRSSDSGFKRWTAGVYYRLMRRLAGPSVP FT AQAGDFRLLSRAAVEALKALPDQQRVYRLLVPWLGFPSGQVTYERAPRTAGRTKYPLGR FT MIRLAVDSVTGFSAAPLRIATWLGAGAFVVCLGLLVYTLTAFALGRTVPGWTSLFTGIV FT FIGAVQLVCVGLLGEYVGRIYTAVQNRPTYFVRHDTAATVPAPGPAPGPAPGSADTLAE FT QDKVG" FT misc_feature 9748..10245 FT /note="Pfam match to entry PF00535 Glycos_transf_2, FT Glycosyl transferases, score 59.60, E-value 6.8e-14" FT RBS 10987..10991 FT misc_feature 10996..11364 FT /note="Pfam match to entry PF00164 Ribosomal_S12, Ribosomal FT protein S12, score 277.20, E-value 2.1e-79" FT CDS 10996..11367 FT /transl_table=11 FT /gene="SCO4659" FT /gene_synonym="rspL" FT /gene_synonym="SCD40A.05" FT /product="30S ribosomal protein S12" FT /note="SCD40A.05, rpsL, 30S ribosomal protein S12, len: 123 FT aa; highly similar to TR:P97222 (EMBL:D83746) Streptomyces FT lividans ribosomal protein S12 RpsL, 123 aa; fasta scores: FT opt: 793 z-score: 1011.4 E(): 0; 99.2% identity in 123 aa FT overlap and to SW:RS12_MYCTU (EMBL:) Mycobacterium FT tuberculosis 30S ribosomal protein S12, RpsL, 124 asa; FT fasta scores: opt: 731 z-score: 933.6 E(): 0; 90.2% FT identity in 123 aa overlap. Contains Pfam match to entry FT PF00164 Ribosomal_S12, Ribosomal protein S12 and match to FT Prosite entry PS00055 Ribosomal protein S12 signature" FT /db_xref="GOA:P0A4A3" FT /db_xref="HSSP:1J5E" FT /db_xref="InterPro:IPR005679" FT /db_xref="UniProtKB/Swiss-Prot:P0A4A3" FT /protein_id="CAB81850.1" FT /translation="MPTIQQLVRKGRQDKVEKNKTPALEGSPQRRGVCTRVFTTTPKKP FT NSALRKVARVRLTSGIEVTAYIPGEGHNLQEHSIVLVRGGRVKDLPGVRYKIIRGSLDT FT QGVKNRKQARSRYGAKKEK" FT misc_feature 11122..11145 FT /note="PS00055 Ribosomal protein S12 signature" FT RBS 11358..11362 FT misc_feature 11370..11837 FT /note="Pfam match to entry PF00177 Ribosomal_S7, Ribosomal FT protein S7p/S5e, score 311.50, E-value 9.7e-90" FT CDS 11370..11840 FT /transl_table=11 FT /gene="SCO4660" FT /gene_synonym="rspG" FT /gene_synonym="SCD40A.06" FT /product="30S ribosomal protein S7" FT /note="SCD40A.06, rpsG, 30S ribosomal protein S7, len: 156 FT aa; highly similar to SW:RS7_STRRP (EMBL:U60191) FT Streptomyces roseosporus 30S ribosomal protein S7 RpsG, 156 FT aa; fasta scores: opt: 979 z-score: 1165.5 E(): 0; 94.9% FT identity in 156 aa overlap. Contains Pfam match to entry FT PF00177 Ribosomal_S7, Ribosomal protein S7p/S5e and match FT to Prosite entry PS00052 Ribosomal protein S7 signature" FT /db_xref="GOA:Q9L0K4" FT /db_xref="HSSP:1HUS" FT /db_xref="InterPro:IPR005717" FT /db_xref="UniProtKB/Swiss-Prot:Q9L0K4" FT /protein_id="CAB81851.1" FT /translation="MPRKGPAPKRPVIIDPVYGSPLVTSLINKVLLNGKRSTAERIVYG FT AMEGLREKTGNDPVITLKRALENIKPTLEVKSRRVGGATYQVPIEVKPGRANTLALRWL FT VGYSRARREKTMTERLLNELLDASNGLGAAVKKREDTHKMAESNKAFAHYRW" FT misc_feature 11427..11507 FT /note="PS00052 Ribosomal protein S7 signature" FT CDS 11880..14006 FT /transl_table=11 FT /gene="SCO4661" FT /gene_synonym="fusA" FT /gene_synonym="SCD40A.07" FT /product="elongation factor G" FT /note="SCD840A.07, fusA, elongation factor G, len: 708 aa; FT similar to SW:EFG_ECOLI (EMBL:X00415) Escherichia coli FT elongation factor G (EF-G) FusA, 703 aa; fasta scores: opt: FT 2711 z-score: 2957.5 E(): 0; 59.9% identity in 708 aa FT overlap and to SW:EFG2_STRCO (EMBL:AL031013) Streptomyces FT coelicolor elongation factor G FusB, SC8A6.10, 686 aa; FT fasta scores: opt: 1279 z-score: 1330.4 E(): 0; 49.1% FT identity in 697 aa overlap. Contains Pfam match to entry FT PF00009 GTP_EFTU, Elongation factor Tu family and to entry FT PF00679 EFG_C, Elongation factor G C-terminus and matches FT to Prosite entries PS00017 ATP/GTP-binding site motif A FT (P-loop) and PS00301 GTP-binding elongation factors FT signature" FT /db_xref="GOA:P40173" FT /db_xref="HSSP:2EFG" FT /db_xref="InterPro:IPR004161" FT /db_xref="UniProtKB/Swiss-Prot:P40173" FT /protein_id="CAB81852.1" FT /translation="MATTSLDLAKVRNIGIMAHIDAGKTTTTERILFYTGVSYKIGEVH FT DGAATMDWMEQEQERGITITSAATTCHWPLEDNDYTINIIDTPGHVDFTVEVERSLRVL FT DGAVTVFDGVAGVEPQSETVWRQADRYGVPRICFVNKLDRTGAEFHRCVDMISDRLGAQ FT PLVMQLPIGAEADFQGVVDLVRMKALVWSADAAKGEMYDVVDIPATHTEAAEEWRGKLV FT EAVAENDEEVMELFLEGQEPTEEQLYAAIRRVTIASGKSSDTTVTPVFCGTAFKNKGVQ FT PLLDAVVRYLPTPLDVEAIEGHDVKDPEVVVKRKPSEDEPLAALAFKIMSDPHLGKLTF FT VRVYSGRLVSGTAVLNSVKGRKERIGKIYRMHANKREEIESVGAGDIVAVMGLKQTTTG FT ETLSDDKSPVILESMDFPAPVIQVAIEPKSKGDQEKLGVAIQRLAEEDPSFQVHTNEET FT GQTIIGGMGELHLEVLVDRMRREFKVEANVGKPQVAYRETIRKTVERVDYTHKKQTGGT FT GQFAKVQIAIEPIEGGDASYEFVNKVTGGRIPKEYIPSVDAGAQEAMQFGILAGYEMTG FT VRVTLIDGGYHEVDSSELAFKIAGSQAFKEAARKASPVLLEPMMAVEVTTPEDYMGDVI FT GDINSRRGQIQAMEERMGARVVKGLVPLSEMFGYVGDLRSKTSGRASYSMQFDSYAEVP FT RNVAEEIIAKAKGE" FT misc_feature 11904..13379 FT /note="Pfam match to entry PF00009 GTP_EFTU, Elongation FT factor Tu family, score 691.50, E-value 4.2e-204" FT misc_feature 11931..11954 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 12033..12080 FT /note="PS00301 GTP-binding elongation factors signature" FT misc_feature 13452..13970 FT /note="Pfam match to entry PF00679 EFG_C, Elongation factor FT G C-terminus, score 370.50, E-value 1.8e-107" FT misc_feature 13725..15373 FT /note="previously sequenced fragment EMBL:X77039" FT RBS 14169..14174 FT CDS 14180..15373 FT /transl_table=11 FT /gene="SCO4662" FT /gene_synonym="tuf1" FT /gene_synonym="SCD40A.08" FT /product="elongation factor TU-1" FT /note="SCD40A.08, tuf1, elongation factor TU-1, len: 397 FT aa; identical to previously sequenced SW:EFT1_STRCO FT (EMBL:X77039) Streptomyces coelicolor elongation factor FT TU-1 (EF-TU-1), Tuf1, 397 aa. Contains Pfam match to entry FT PF00009 GTP_EFTU, Elongation factor Tu family and matches FT to Prosite entries PS00017 ATP/GTP-binding site motif A FT (P-loop) and PS00301 GTP-binding elongation factors FT signature" FT /db_xref="GOA:P40174" FT /db_xref="HSSP:1ETU" FT /db_xref="InterPro:IPR004160" FT /db_xref="UniProtKB/Swiss-Prot:P40174" FT /protein_id="CAB81853.1" FT /translation="MAKAKFERTKPHVNIGTIGHIDHGKTTLTAAITKVLHDAYPDINE FT ASAFDQIDKAPEERQRGITISIAHVEYQTEARHYAHVDCPGHADYIKNMITGAAQMDGA FT ILVVAATDGPMPQTKEHVLLARQVGVPYIVVALNKADMVDDEEILELVELEVRELLSEY FT EFPGDDVPVVKVSALKALEGDKEWGNSVLELMKAVDEAIPEPERDVDKPFLMPIEDVFT FT ITGRGTVVTGRIERGVLKVNETVDIIGIKTEKTTTTVTGIEMFRKLLDEGQAGENVGLL FT LRGIKREDVERGQVIIKPGSVTPHTEFEAQAYILSKDEGGRHTPFFNNYRPQFYFRTTD FT VTGVVTLPEGTEMVMPGDNTEMKVELIQPVAMEEGLKFAIREGGRTVGAGQVTKINK" FT misc_feature 14207..15310 FT /note="Pfam match to entry PF00009 GTP_EFTU, Elongation FT factor Tu family, score 528.80, E-value 3.8e-155" FT misc_feature 14234..14257 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 14336..14383 FT /note="PS00301 GTP-binding elongation factors signature" FT CDS complement(15363..15716) FT /transl_table=11 FT /gene="SCO4663" FT /gene_synonym="SCD40A.09c" FT /product="hypothetical protein SCD40A.09c" FT /note="SCD40A.09c, unknown, len: 117 aa" FT /db_xref="InterPro:IPR005158" FT /db_xref="UniProtKB/TrEMBL:Q9L0K2" FT /protein_id="CAB81854.1" FT /translation="MQIRVSRLRTLLGRAARPATIATRPSGYVLTTEPGTVDAVLFTAL FT VAGARRLGHEDRREEAVARLRTAAALWQGDFLSGLDPTAHGERTRTTEVVRALSGISPC FT QVGSTDKQAELTC" FT CDS complement(15846..17681) FT /transl_table=11 FT /gene="SCO4664" FT /gene_synonym="SCD40A.10c" FT /product="putative integral membrane protein" FT /note="SCD40A.10c, possible membrane protein, len: 611 aa; FT similar to C-terminal region of TR:CAB71211 (EMBL:AL138538) FT Streptomyces coelicolor putative membrane protein FT SC6D10.16, 907 aa; fasta scores: opt: 262 z-score: 270.5 FT E(): 1.2e-07; 29.0% identity in 630 aa overlap. Contains FT possible hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9L0K1" FT /db_xref="InterPro:IPR003838" FT /db_xref="UniProtKB/TrEMBL:Q9L0K1" FT /protein_id="CAB81855.1" FT /translation="MPGGAGVRVLTGAERRYADADPHRDEEALTALNALFGTAGGVSAF FT VSVFVVSSTFAFAVAQRRREFGLLRTAGATPGQLRRTVLAEAAVVGVLASGTGCVLGAY FT GAPPLTHWVVGEGLAPAWFTLGDHTWPYHLAFWTGLLVALCGAAAASWRAGRTGPVEAL FT REAAADAGATTRGRWLSGLALLLTALVTLVLALADDPGDLLHRKTYVTRPMLLITAAAL FT LAPVVVRPLTRLLTRLPARLPGATGLLVRENAATGVRRTAALAAPVLVTVALTGSLLGA FT VATLDGAKAAETRARTTAAYVAAAPSDAGFDPATLDRLRAVPGARISPSAAGEVYVLED FT GVALVRSQARAVADPGALAATARLPVAKGRVADLDDRSIIVNEEWREHTVGRSVRVWLG FT DGTERVLRIAAVLETGTGDNGVYVTAANAAGAPVDRVDVALADGADPDAVAAGLRAAVA FT PSGGRVSSGHAWADAASPGSEGATRAGLLLVLGIALLYTGISVVNTVLMAAPARIREQA FT VLRLAGATDGQVLRVVAAESLTVVAVGTLLGLPVAGLDLAGMWAALALLSVPAPPVLPW FT AAAGTVAGVCAVLAATASVVPAALALRRRGGRPGG" FT CDS complement(17697..18326) FT /transl_table=11 FT /gene="SCO4665" FT /gene_synonym="SCD40A.11c" FT /product="putative membrane protein" FT /note="SCD40A.11c, possible membrane protein, len: 209 aa. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9L0K0" FT /protein_id="CAB81856.1" FT /translation="MLTVALCTLRTRWVTFTGSFVALALGVALLAVTGRALAASLDAPE FT RAPERFAAAPVVVRGQDTLRVPTPSGDRTAEQARVRPVPAPVVARLERLGTVVEDRSFP FT VRVRGGRGPGAPVGHPWSTAAFAPYRIDAGRAPRAADEVVVTGGWAAPGERVRTDRGTL FT RVVGTVPGLGFEDAVFFTDARAAELAPRSVQLAVDAEASAVREAVR" FT CDS complement(18320..19060) FT /transl_table=11 FT /gene="SCO4666" FT /gene_synonym="SCD40A.12c" FT /product="putative ABC-transporter ATP-binding protein" FT /note="SCD840A.12c, possible ABC-transporter ATP-binding FT protein, len: 246 aa; similar to TR:Q9XAA7 (EMBL:AL096837) FT Streptomyces coelicolor putative ABC-transporter FT ATP-binding protein SCF43A.08, 264 aa; fasta scores: opt: FT 984 z-score: 1127.0 E(): 0; 64.0% identity in 239 aa FT overlap and to TR:CAB76999 (EMBL:AL159178) Streptomyces FT coelicolor putative ABC transporter ATP-binding protein FT SCH22A.30, 252 aa; fasta scores: opt: 907 z-score: 718.9 FT E(): 1.5e-34; 61.0% identity in 236 aa overlap. Contains FT Pfam match to entry PF00005 ABC_tran, ABC transporter and FT matches to Prosite entries PS00017 ATP/GTP-binding site FT motif A (P-loop) and PS00211 ABC transporters family FT signature" FT /db_xref="GOA:Q9L0J9" FT /db_xref="HSSP:1L2T" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9L0J9" FT /protein_id="CAB81857.1" FT /translation="MTSDDAIRLSSVSRRYGAGEGTVTALDDVSLALRRGSFTAVMGPS FT GSGKSTLLQCAAGLDRPTSGSVVVGGTELTGLSQRRLTLLRRERVGFVFQAFNLLPSLT FT AAQNVALPLRLAGRRPPRGRVREALRQVGLADRARHRPAELSGGQQQRVALARALITRP FT QVLFADEPTGALDSRTGREVLTLLRAMADGEGRTVVMVTHDPVAASYADRVLFLVDGRV FT HDELTGSGPDGIATRMTRLEAAPC" FT RBS complement(18334..18338) FT misc_feature complement(18401..18955) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 217.10, E-value 2.6e-61" FT misc_feature complement(18584..18628) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(18911..18934) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(19064..19068) FT CDS 19231..20526 FT /transl_table=11 FT /gene="SCO4667" FT /gene_synonym="SCD40A.13" FT /product="putative two-component system sensor kinase" FT /note="SCD40A.13, possible two-component system sensor FT kinase, len: 431 aa; C-terminal region similar to TR:Q9ZBS5 FT (EMBL:AL034446) Streptomyces coelicolor putative sensor FT kinase SC1A9.27c, 303 aa; fasta scores: opt: 378 z-score: FT 412.0 E(): 1.6e-15; 31.9% identity in 313 aa overlap. FT Contains possible N-terminal region hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q9L0J8" FT /db_xref="InterPro:IPR011712" FT /db_xref="UniProtKB/TrEMBL:Q9L0J8" FT /protein_id="CAB81858.1" FT /translation="MRSRDLWQALSARRYLLSAWPWRATAYLVTGAVAGAATLVGLAVA FT LVVGGVLTVVLVGLPLLVLTALAGIPLARLERQRLRLIDRAPAPARPVRQPPATGPWPW FT LITRLRERATWRELGHALLFALVLWPLDALAVALALGAPLHLAGTPLVMATAGGGEEAK FT VLKQWTVTTWPAASGVAALGLLLLALGGYALGLAAGVRAELARVLVGAPGEGDPEARVG FT ELTRSRARLVDAFEAERRRIERDLHDGAQQRLVALTMALGLARLDAPPGPLADQLAKAH FT GEAGRALEELRELIHGIHPKVLADYGLPAAVADAADRSAVPVDVALELPGRLPRAVEAA FT AYFVVCEALANVGRHSGADRAEVTGGHRDGRLLLHVRDDGRGGADAAAGSGLTGLADRV FT SVLDGRLSLSSPPGGPTLLSVEIPCEWTERFA" FT CDS 20526..21158 FT /transl_table=11 FT /gene="SCO4668" FT /gene_synonym="SCD40A.14" FT /product="putative two-component system response regulator" FT /note="SCD40A.14, possible two-component system response FT regulator, len: 210 aa; similar to TR:CAB61727 FT (EMBL:AL133220) Streptomyces coelicolor SCC75A.27c, 228 aa; FT fasta scores: opt: 732 z-score: 839.5 E(): 0; 58.6% FT identity in 210 aa overlap. Contains two Pfam matches to FT entries PF00072 response_reg, Response regulator receiver FT domain and PF00196 GerE, Bacterial regulatory proteins, FT luxR family. Contains also possible helix-turn-helix motif FT at residues 162..183 (+3.44 SD)" FT /db_xref="GOA:Q9L0J7" FT /db_xref="HSSP:1RNL" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9L0J7" FT /protein_id="CAB81859.1" FT /translation="MLAEDSVLLRDGLTGLLARFGHEVVAAVGDAQALVGAVAEHVPDV FT VVTDVRMPPGFQDEGLHAAVRLRGERPTLPVLVLSQYVQRAYAAELLDSGDGTGVGYLL FT KDRVGQVEEFVDALAEVAAGGTVVDPEVVRQLLRRRRDPLERLSPREREVLALIAEGRS FT NAAIARQLVVSEAAVGKHIGSILAKLDLPPATETHRRVLAVLTYLRG" FT misc_feature 20544..20879 FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 39.00, E-value 1.1e-07" FT misc_feature 20955..21152 FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 39.50, E-value FT 7.8e-08" FT CDS 21326..22465 FT /transl_table=11 FT /gene="SCO4669" FT /gene_synonym="SCD40A.15" FT /product="putative membrane protein" FT /note="SCD40A.15, possible membrane protein, len: 379 aa; FT similar to TR:CAB66261 (EMBL:AL136518) Streptomyces FT coelicolor putative membrane protein SCC123.21c, 356 aa; FT fasta scores: opt: 350 z-score: 356.2 E(): 2.1e-12; 30.1% FT identity in 356 aa overlap. Contains possible hydrophobic FT membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9L0J6" FT /protein_id="CAB81860.1" FT /translation="MSSVPPPDRSDGEPAPSISDEQLEAFLREAADGGGGSAPKEPSAR FT ARMVARRLREEAEPEPWRAPQGSPRGDGRGRRRLVGAVVGVVVLAALAVVAVRPSLVLD FT RLPGGDDASATPTLAAESARPTGAPGEAAGAERATREHPFRGSPAERWAEGADAIEVPA FT AKPLSGMSKDDVAFALRRTKELLVAANLDPAVLRGERPDEALDVLDPKQPELLPKLRRS FT LSDPDADHDPLRLFTRFDPAETRLAGDVVKVRGRMTLAAGEPGVVKVDADYTFVYPLVR FT AGDADGPVARTIIRRVLTLTLNDPAKWNVTEGKLLVEKYFSEYGNTDCDVYDGYLHPGF FT PDDDGPGGARPTGPPTDPYDRSRPLTGSGPGGCGQVTRT" FT CDS complement(22550..23941) FT /transl_table=11 FT /gene="SCO4670" FT /gene_synonym="SCD40A.16c" FT /product="putative serine protease precursor" FT /note="SCD840A.16c, probable serine protease precursor, FT len: 463 aa; similar to SW:PRTC_STRGR (EMBL:L29018) FT Streptomyces griseus serine protease C precursor (EC FT 3.4.21.-) SprC, 457 aa; fasta scores: opt: 1761 z-score: FT 1679.7 E(): 0; 59.4% identity in 458 aa overlap and to FT TR:Q9XA96 (EMBL:AL096837) Streptomyces coelicolor putative FT serine protease SCF43A.19, 458 aa; fasta scores: opt: 1637 FT z-score: 1264.0 E(): 0; 55.9% identity in 460 aa overlap. FT Contains Pfam match to entry PF00089 trypsin, Trypsin and FT matches to Prosite entries PS00135 Serine proteases, FT trypsin family, serine active site and PS00178 FT Aminoacyl-transfer RNA synthetases class-I signature. FT Contains also possible N-terminal region signal peptide FT sequence" FT /db_xref="GOA:Q9L0J5" FT /db_xref="HSSP:1ED7" FT /db_xref="InterPro:IPR018114" FT /db_xref="UniProtKB/TrEMBL:Q9L0J5" FT /protein_id="CAB81861.1" FT /translation="MPHRHRHHRAVGAAVAATAALLVAGLSGSASAGTAPAGSAPTAAE FT TLRTDAAPPALLKAMQRDLGLDRRQAERRLVNEAEAGATAGRLRAALGGDFAGAWVRGA FT ESGTLTVATTDAGDVAAIEARGAEAKVVRHSLADLDAAKARLDTAAAGLNTADAPVWYV FT DTRTNTVVVEAIRPAAARSLLTAAGVDGSLAHVKNRTERPRTFYDLRGGEAYYINNSSR FT CSIGFPITKGTQQGFATAGHCGRAGSSTTGANRVAQGTFQGSIFPGRDMAWVATNSSWT FT ATPYVLGAGGQNVQVTGSTASPVGASVCRSGSTTGWHCGTVTQLNTSVTYQEGTISPVT FT RTTVCAEPGDSGGSFISGSQAQGVTSGGSGDCRTGGETFFQPINALLQNYGLTLKTTGG FT DDGGGDDGGGDDGGEEPGGTWAAGTVYQPGDTVTYGGATFRCLQGHQAYAGWEPPNVPA FT LWQRV" FT misc_feature complement(22631..22660) FT /note="PS00178 Aminoacyl-transfer RNA synthetases class-I FT signature" FT misc_feature complement(22781..23317) FT /note="Pfam match to entry PF00089 trypsin, Trypsin, score FT 58.90, E-value 7.8e-18" FT misc_feature complement(22874..22909) FT /note="PS00135 Serine proteases, trypsin family, serine FT active site" FT RBS complement(23949..23953) FT CDS complement(24093..25040) FT /transl_table=11 FT /gene="SCO4671" FT /gene_synonym="SCD40A.17c" FT /product="putative lysR-family regulatory protein" FT /note="SCD40A.17c, probable lysR-family regulatory protein, FT len: 315 aa; similar to SW:MPRR_STRCO (EMBL:Z11929) FT Streptomyces coelicolor small neutral protease regulatory FT protein MprR, 316 aa; fasta scores: opt: 541 z-score: 619.1 FT E(): 4.7e-27; 36.7% identity in 308 aa overlap. Contains FT Pfam match to entry PF00126 HTH_1, Bacterial regulatory FT helix-turn-helix protein, lysR family and match to Prosite FT entry PS00044 Bacterial regulatory proteins, lysR family FT signature. Contains also possible helix-turn-helix motif at FT residues 18..39 (+4.31 SD). Contains also TTA leucine FT codon, possible target for bldA regulation" FT /db_xref="GOA:Q9L0J4" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9L0J4" FT /protein_id="CAB81862.1" FT /translation="MELELRHLKTVRAIADAGSLTRAATALGLAQPALSAQLKRIERAL FT GGALFVRGRHGVRATALGELVLERSRIVLPAVTELQQEAARFARAPRTAERLRIGGTHG FT PLLGALLDRLAGVAPDARMTTCTSWSERELAGQLAEGRLDFALAGTCGTASPPAGEGLV FT WREVAVDPVFVMMTDGHPLAHRAEVDLTALADEEWACVPGDGCFGDCFTASCARAGFTP FT RRMYETDTASLVHLVQVGRAVGLCRATFPTTPGIVTRPLADTPLTWRHLLGWHAATQRR FT DTAAAVLAQARMAHASVAANSDSYTEWMSAHRVP" FT misc_feature complement(24600..25028) FT /note="Pfam match to entry PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix protein, lysR family, score FT 99.80, E-value 5.3e-26" FT misc_feature complement(24723..24725) FT /gene="none" FT /note="TTA Leucine codon. Possible target for bldA FT regulation" FT misc_feature complement(24894..24986) FT /note="PS00044 Bacterial regulatory proteins, lysR family FT signature" FT CDS complement(25126..26895) FT /transl_table=11 FT /gene="SCO4672" FT /gene_synonym="SCD40A.18c" FT /product="putative secreted protein" FT /note="SCD40A.18c, possible secreted protein, len: 589 aa. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q9L0J3" FT /protein_id="CAB81863.1" FT /translation="MTHTSRRGVLAAFAASAATVPFGGAAAASPARATATAASAVDPAA FT ASAAPAGLTAARSSVTLPPLNPAYFSGLTLDSALTATVLPGTPARTEVTSGGRRVALLT FT HGARSVLLPGPERTFTENKKPFVDDFARTLPDTSLPVGDRAYWGTSPGGGSWSTLGPVE FT SDYAVVPGAGIITLTTDYASRHASLRDGEVTDVDVRSVARFDKVPEGDACSYALSFGYQ FT DTHNNYRARLSFTTSGAVQLRVEKEVDDTVTQLAPAVALADGVPAGTDWTIRVRREGTR FT VRAKAWPSAGTEPSAWSFDATDDTFGKGRVGLRALANRGCTNLPVTLRVGRFQVDAANW FT AEPPAVTHSDWVRVLPEPFDGVWTPQLEQVVRGWSGSPAPDVLAHAAMFLAGASPVVAG FT SGPAEGRQVMGEAGYGYLDPQGYRYEGADFHEYMGTGWTFPDGAHTGPSSRQTGNLDCS FT GYTRMVYGYHMGVPLAAGEDTSGTRLPRKSRDMADHSPGVRIARTDGTLPPPAEQLQPG FT DLVLFNADSGDDNAVATTDHVGIYLGADTAGRRRFLSSRKTVNGPTMSDLGGASLLDGT FT GTYARTLHTVHRI" FT CDS complement(26900..27919) FT /transl_table=11 FT /gene="SCO4673" FT /gene_synonym="SCD40A.19c" FT /product="putative deoR-family transcriptional regulator" FT /note="SCD40A.19c, possible deoR-family transcriptional FT regulator, len: 339 aa; similar to TR:Q54822 (EMBL:L37338) FT Streptomyces peucetius putative repressor DnrO, 340 aa; FT fasta scores: opt: 660 z-score: 749.1 E(): 0; 38.7% FT identity in 333 aa overlap. Contains match to Prosite entry FT PS00894 Bacterial regulatory proteins, deoR family FT signature and possible helix-turn-helix motif at residues FT 27..48 (+5.18 SD)" FT /db_xref="GOA:Q9L0J2" FT /db_xref="InterPro:IPR018356" FT /db_xref="UniProtKB/TrEMBL:Q9L0J2" FT /protein_id="CAB81864.1" FT /translation="MADFRTVLSTSARLLRLVSLLAVRPAWTCGELAERMEVTERTVRR FT DVARLRELGYTVDSDPGPWGGYRLRPGTRTPPLILDDEEALAVAVGLREAALSGALGGD FT QAALSALLKLRQVLPKRLGDRLEDMDAAFVQTPRAGEPQVAAGTLLELAAACRRGERAR FT MAYRDWGGRASVRDVDPYRLVHTGRRWYFVARDVARGEWRTFRADRVERVQPTGRAVEF FT TEPLPDPALLVSRASATGPYAVLATVRLPVPMEQALRSIPATVGLHRADGPDATVVEIG FT GSSAEGLARYLVSLATPLRVLAPDAVRRALLHRVHELLEDNVEEMDRPVPDAPPRKRS" FT misc_feature complement(27779..27883) FT /note="PS00894 Bacterial regulatory proteins, deoR family FT signature" FT CDS 27931..28368 FT /transl_table=11 FT /gene="SCO4674" FT /gene_synonym="SCD40A.20" FT /product="hypothetical protein SCD840A.20" FT /note="SCD40A.20, hypothetical protein, len: 145 aa; FT similar to TR:O06633 (EMBL:Z95618) Mycobacterium FT tuberculosis hypothetical 12.5 kD protein MTCY07H7A.08c, FT 115 aa; fasta scores: opt: 249 z-score: 314.3 E(): 4.5e-10; FT 39.5% identity in 119 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9L0J1" FT /protein_id="CAB81865.1" FT /translation="MTRTEPVLVTSYGPPMTTTQNASAPTFRYSAVTFDCSDPAALARF FT WGEALDLPVAFNTDDFYLLGGKDGAPGLGFCRLPDYRPPTWPGTDQEKQAHIDVGVEDL FT DAGEARLLALGATKPDFQPSPDRWRVLLDPAGHPFCVSTVA" FT CDS complement(28381..29289) FT /transl_table=11 FT /gene="SCO4675" FT /gene_synonym="SCD40A.21c" FT /product="conserved hypothetical protein SCD40A.21c" FT /note="SCD40A.21c, hypothetical protein, len: 302 aa; FT similar to TR:Q9XD94 (EMBL:AF106004) Streptomyces FT coelicolor hypothetical 34.1 kD protein, 304 aa; fasta FT scores: opt: 850 z-score: 992.1 E(): 0; 45.0% identity in FT 300 aa overlap. Contains match to Prosite entry PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign." FT /db_xref="UniProtKB/TrEMBL:Q9L0J0" FT /protein_id="CAB81866.1" FT /translation="MVSSSHEAMHRIFQHDPGLFSRVTHFLGIDLPRPIGATALPTDLT FT EASPVERRVDTLLRFETAERGPFLLAVEAQGKKDPDKPASWAYYVSYLWTKYRLPTALL FT VVCQDHATAKWAQRAVTSGPPELPTLTLRPVVAGPHNMPVITDPDEARADLVLASLAAI FT THAAEPVVNAILKALSTALSDAPEDIAAPIVEFTAHGLGNRPARHLWRNLVAVDLSFYK FT SYISEEIRDEGREQGREQGREQGRAQQGAQDVLLVLEQRGLDIPDGVRTRITECGDPEV FT LRHWLARAVTASSAEAVFESE" FT misc_feature complement(29167..29253) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS complement(29307..30179) FT /transl_table=11 FT /gene="SCO4676" FT /gene_synonym="SCD31.01c" FT /gene_synonym="SCD40A.22c" FT /product="hypothetical protein" FT /note="SCD31.01c, unknown (fragment), len: >147 aa" FT /note="SCD40A.22c, unknown (fragment), len: > 176 aa" FT /db_xref="UniProtKB/TrEMBL:Q8CJT0" FT /protein_id="CAD55213.1" FT /translation="MGTENTSAPPRAQSAPADNPTRTRRHGGGIVHENTRHTTRFVVIG FT NHLVQHKELSLLAIGLSCHLQSLPTGAGADIKSLAARFPEGPTRIAAALRELEAHGYLR FT RERHRTQTGRIVTRTVSCNQPHADRRREPADTGCPPAKRTPPPQRRTVQKALPAVPQPS FT STAPALLQTAIDLLATLRRHDPRLLLSATDTAHLVPGVAAWLERGVAPSAVRHALTTGL FT PDEPLRRPAALLAHRLTDRLPPPPPFGTPSAAGPPPRHPLQNCEGCDRGFRAPYPENRC FT RDCRAASHP" FT CDS complement(30427..30861) FT /transl_table=11 FT /gene="SCO4677" FT /gene_synonym="SCD31.02c" FT /product="putative regulatory protein" FT /note="SCD31.02c, possible regulatory protein, len: 144 aa; FT similar to TR:CAB60156 (EMBL:AL132824) Streptomyces FT coelicolor putative regulatory protein SCAH10.02, 160 aa; FT fasta scores: opt: 396 z-score: 500.7 E(): 1.9e-20; 51.7% FT identity in 143 aa overlap" FT /db_xref="GOA:Q9L0G5" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9L0G5" FT /protein_id="CAB82045.1" FT /translation="MNQESTTELTASVRNFSVQLSPTPRGARLARLLATEQLRSWGLPP FT DPARLLVAELANNAADHGRVPGRDFRLTLYVVGDILRIEVTDTRGQELPAPQKPASDAE FT SGRGLLLVEALAHRWGVTEGRFPRKTVWAELRCTPPEPTF" FT RBS 30969..30973 FT CDS 30974..31822 FT /transl_table=11 FT /gene="SCO4678" FT /gene_synonym="SCD31.03" FT /product="conserved hypothetical protein" FT /note="SCD31.03, conserved hypothetical protein, len: 282 FT aa; similar to various hypothetical proteins, e.g. FT TR:CAB66187 (EMBL:AL136500) Streptomyces coelicolor FT hypothetical 31.7 kD protein SC1G2.15c, 284 aa; fasta FT scores: opt: 1359 z-score: 1611.1 E(): 0; 71.7% identity in FT 279 aa overlap" FT /db_xref="GOA:Q9L0G4" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q9L0G4" FT /protein_id="CAB82046.1" FT /translation="MAVETDESGWEVDPDDEWGVAVITTVGRQLKLRREAAGMRAGDFG FT VAVGYGEDLVYKVEGGKRIPRQEYLDRADEVLGAGGLISAAWEDVKKVRYPKKVRELVK FT LEGKAVEIGIYECSSVHGLLQTPEHARALMEAAQPPYSADDVQRMVAARMARQSVFERD FT PAPSIHFVLEEAPLRRPVGGTMVKQQQLERLLEVGSLNHVSLQVMPTNTEAHPGVDGKI FT ELLKFPDGTAVGRSDGAFNGRPTAEPRELRILELRYGTIRAQALPPRESLAFIEKLLGD FT T" FT RBS 31811..31814 FT CDS 31819..32010 FT /transl_table=11 FT /gene="SCO4679" FT /gene_synonym="SCD31.04" FT /product="conserved hypothetical protein" FT /note="SCD31.04, conserved hypothetical protein, len: 63 FT aa; similar to TR:CAB66186 (EMBL:AL136500) Streptomyces FT coelicolor hypothetical 7.7 kD protein SC1G2.14c, 73 aa; FT fasta scores: opt: 265 z-score: 399.0 E(): 8.5e-15; 66.0% FT identity in 53 aa overlap" FT /db_xref="InterPro:IPR007278" FT /db_xref="UniProtKB/TrEMBL:Q9L0G3" FT /protein_id="CAB82047.1" FT /translation="MIRETEPVWFKSSYSSGTDGNSCVELAVTPATIHIRDSKHTDGPR FT LTLTPAAWSSFLPYASRR" FT CDS complement(31961..32851) FT /transl_table=11 FT /gene="SCO4680" FT /gene_synonym="SCD31.05c" FT /product="putative DNA-binding protein" FT /note="SCD31.05c, possible DNA-binding protein, len: 296 FT aa; similar to TR:CAB53273 (EMBL:AL109972) Streptomyces FT coelicolor putative DNA binding protein SCJ9A.12c, 279 aa; FT fasta scores: opt: 782 z-score: 910.0 E(): 0; 46.1% FT identity in 271 aa overlap" FT /db_xref="GOA:Q9L0G2" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q9L0G2" FT /protein_id="CAB82048.1" FT /translation="MKYAELGSFLRSRRERIRPADVGLPAGPRRRVPGLRREEVAHLAG FT ASVDYYNELERGAGSQPSEQMLAALARALRLSADERDYLYRLADRPVPVPGGPASHVHP FT GMLDLLGRMTSTPAQVITDLHVTLVQNPLAVALLGDQSGYRGPRASFVHRWFTEPEARL FT LYPEADHAYQSRSFVADLRAAAARRDAKDTEAGAMVRTLLGVSPEFAALWADHDVAFRR FT HDRKRLVHPVIGLVEVNCLNLFSEDGRQRLLWFTPAVGTESAGLLELLSVVGTQEVSEV FT SAATRTAGSSTRRQG" FT CDS 32896..33705 FT /transl_table=11 FT /gene="SCO4681" FT /gene_synonym="SCD31.06" FT /product="putative short chain dehydrogenase" FT /note="SCD31.06, probable short chain dehydrogenase, len: FT 296 aa; similar to TR:CAB56135 (EMBL:AL117669) Streptomyces FT coelicolor putative short chain dehydrogenase SCF12.09, 249 FT aa; fasta scores: opt: 1003 z-score: 1070.0 E(): 0; 65.2% FT identity in 244 aa overlap and to SW:SDR1_PICAB FT (EMBL:X74115) Picea abies short-chain type FT dehydrogenase/reductase (EC 1.-.-.-) Sdr1,271 aa; fasta FT scores: opt: 576 z-score: 619.1 E(): 4.7e-27; 47.8% FT identity in 251 aa overlap. Contains Pfam matches to FT entries PF00106 adh_short, short chain dehydrogenase and FT PF00678 adh_short_C2, Short chain dehydrogenase/reductase FT C-terminus" FT /db_xref="GOA:Q9L0G1" FT /db_xref="HSSP:1GZ6" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9L0G1" FT /protein_id="CAB82049.1" FT /translation="MGWHPLAAPSDRAHRGAMTTHTNQQTAAERVAVVTGGSRGIGRAV FT SRKLAEDGLAVVVNYASDASAADETVTAITEAGGRAIAVQADVAEEKEVAALFDRAADE FT FGGVDVVVNSAGRMTLSPIADLDLAALDAMHRTNIRGTFVVAQQAARRLRAGGAFIGFS FT TSVVGTQFPTYGAYAASKGAVEAMTMILARELRGRDVTVNTVAPGPTATDLFLDGKTPE FT QVDKLAKTPPLERLGTPEDIAAVVAFLGSPAGHWVNGQILRANGGMI" FT misc_feature 32983..33534 FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 199.10, E-value 7.1e-56" FT misc_feature 33595..33687 FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 36.40, FT E-value 1.2e-08" FT CDS 33707..33916 FT /transl_table=11 FT /gene="SCO4682" FT /gene_synonym="SCD31.07" FT /product="putative tautomerase" FT /note="SCD31.07, possible tautomerase, len: 69 aa; similar FT to TR:O25581 (EMBL:AE000602) Helicobacter pylori FT 4-oxalocrotonate tautomerase (DmpI) HP0924, 68 aa; fasta FT scores: opt: 114 z-score: 175.1 E(): 0.025; 32.2% identity FT in 59 aa overlap. Contains Pfam match to entry PF01361 FT Tautomerase, Tautomerase enzyme" FT /db_xref="GOA:Q9L0G0" FT /db_xref="InterPro:IPR004370" FT /db_xref="UniProtKB/TrEMBL:Q9L0G0" FT /protein_id="CAB82050.1" FT /translation="MPFAHFKVPAGTLSAEDKKKIVERTTDLYAEIYGERARPTTVVLV FT DEVPDGGWGVAGNVLTAAMLNGDG" FT misc_feature 33755..33871 FT /note="Pfam match to entry PF01361 Tautomerase, Tautomerase FT enzyme, score 26.60, E-value 0.00059" FT CDS 34064..35449 FT /transl_table=11 FT /gene="SCO4683" FT /gene_synonym="gdhA" FT /gene_synonym="SCD31.08" FT /product="NADP-specific glutamate dehydrogenase" FT /note="SCD31.08, gdhA, NADP-specific glutamate FT dehydrogenase, len: 461 aa; similar to TR:O87403 FT (EMBL:AF056335) Bacillus licheniformis NADP-specific FT glutamate dehydrogenase (EC 1.4.1.4) GdhA, 460 aa; fasta FT scores: opt: 1759 z-score: 1940.3 E(): 0; 59.1% identity in FT 435 aa overlap and to SW:DHE4_ECOLI (EMBL:J01615) FT Escherichia coli NADP-specific glutamate dehydrogenase (EC FT 1.4.1.4) GdhA, 447 aa; fasta scores: opt: 1683 z-score: FT 1856.8 E(): 0; 58.7% identity in 446 aa overlap. Contains FT Pfam match to entry PF00208 GLFV_dehydrog, FT Glutamate/Leucine/Phenylalanine/Valine dehydrogenase and FT match to Prosite entry PS00074 Glu / Leu / Phe / Val FT dehydrogenases active site" FT /db_xref="GOA:Q9L0F9" FT /db_xref="HSSP:1AUP" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9L0F9" FT /protein_id="CAB82051.1" FT /translation="MPAVPERAPVTTRSETQSTLDHLLTEIELRNPAQPEFHQAAHEVL FT ETLAPVVAARPEYAEPGLIERLVEPERQVMFRVPWQDDQGRVRVNRGFRVEFNSALGPY FT KGGLRFHPSVNLGVIKFLGFEQIFKNALTGLGIGGGKGGSDFDPHGRSDAEVMRFCQSF FT MTELYRHIGEHTDVPAGDIGVGGREIGYLFGQYRRITNRWESGVLTGKGQGWGGSLIRP FT EATGYGNVLFAAAMLRERGEDLEGQTAVVSGSGNVAIYTIEKLTALGANAVTCSDSSGY FT VVDEKGIDLDLLKQIKEVERGRVDAYAERRGASARFVPGGSVWDVPADLALPSATQNEL FT DENAAATLVRNGVKAVSEGANMPTTPEAVHLLQKAGVAFGPGKAANAGGVAVSALEMAQ FT NHARTSWTAARVEEELADIMTSIHTTCHETAERYDAPGDYVTGANIAGFERVADAMLAQ FT GVI" FT misc_feature 34271..35440 FT /note="Pfam match to entry PF00208 GLFV_dehydrog, FT Glutamate/Leucine/Phenylalanine/Valine dehydrogenase, score FT 610.80, E-value 7.8e-180" FT misc_feature 34466..34507 FT /note="PS00074 Glu / Leu / Phe / Val dehydrogenases active FT site" FT RBS 35787..35791 FT misc_feature 35798..35998 FT /note="Pfam match to entry PF00313 CSD, 'Cold-shock' FT DNA-binding domain, score 137.80, E-value 2e-37" FT CDS 35798..36001 FT /transl_table=11 FT /gene="SCO4684" FT /gene_synonym="scoF3" FT /gene_synonym="SCD31.09" FT /product="cold shock protein" FT /note="SCD31.09, scoF3, cold shock protein, len: 67 aa; FT highly similar to TR:O54117 (EMBL:AL021529) Streptomyces FT coelicolor cold-shock domain protein SC10A5.26c, 67 aa; FT fasta scores: opt: 432 z-score: 604.3 E(): 3.1e-26; 97.0% FT identity in 67 aa overlap and to SW:CSPF_STRCO FT (EMBL:X92686) Streptomyces coelicolor cold shock protein FT ScoF, 67 aa; fasta scores: opt: 370 z-score: 520.7 E(): FT 1.4e-21; 80.6% identity in 67 aa overlap. Contains Pfam FT match to entry PF00313 CSD, 'Cold-shock' DNA-binding domain FT and match to Prosite entry PS00352 'Cold-shock' DNA-binding FT domain signature" FT /db_xref="GOA:Q9L0F8" FT /db_xref="HSSP:1MJC" FT /db_xref="InterPro:IPR019844" FT /db_xref="UniProtKB/TrEMBL:Q9L0F8" FT /protein_id="CAB82052.1" FT /translation="MATGTVKWFNAEKGFGFIEQDGGGADVFAHYSNIAAQGFRELLEG FT QKVNFDIAQGQKGPTAENIVLA" FT misc_feature 35840..35899 FT /note="PS00352 'Cold-shock' DNA-binding domain signature" FT stem_loop 36029..36072 FT /note="6292 TGCAGCTGGGGCCCGCATCC 6311-6316 FT GGGTGCGGGCCCCAGCTGCA 6335. 19/20 (95%) matches, 0 gaps" FT CDS 36197..37618 FT /transl_table=11 FT /gene="SCO4685" FT /gene_synonym="SCD31.10" FT /product="putative DEAD-box RNA helicase" FT /note="SCD31.10, probable DEAD-box RNA helicase, len: 473 FT aa; similar to TR:O54116 (EMBL:AL021529) Streptomyces FT coelicolor DEAD-box RNA helicase SC10A5.25c, 498 aa; fasta FT scores: opt: 2591 z-score: 2737.2 E(): 0; 88.1% identity in FT 461 aa overlap and to SW:RHLE_ECOLI (EMBL:L02123) FT Escherichia coli putative ATP-dependent RNA helicase RhlE, FT 454 aa; fasta scores: opt: 845 z-score: 896.7 E(): 0; 36.8% FT identity in 427 aa overlap. Contains Pfam match to entry FT PF00270 DEAD, DEAD/DEAH box helicase Pfam match to entry FT PF00271 helicase_C, Helicases conserved C-terminal domain FT 2x PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9L0F7" FT /db_xref="HSSP:1QDE" FT /db_xref="InterPro:IPR018114" FT /db_xref="UniProtKB/TrEMBL:Q9L0F7" FT /protein_id="CAB82053.1" FT /translation="MNRTGMNDRMNDRPARTGKARTRALAVQGEFAHPETLTPALPAAA FT RFADLDMPAELLAALESQGVTVPFPIQAATLPNSLAGRDVLGRGRTGSGKTLAFGLALL FT ARTAGRRAEPGQPLGLVLVPTRELAQQVTDALRPYARSVKLRLTAVVGGMSIGRQASAL FT RGGVEVVVATPGRLKDLIDRGDCRLNQVSVTVLDEADQMADMGFMPQVTALLDQVRPEG FT QRMLFSATLDRNVDLLVRRYLSDPVVHSVDPSAGAVTTMEHHVLHVHGADKHAATTEIA FT ARDGRVLMFLDTKHAVDRLTDHLLNSGVRAAALHGGKSQSQRTRTLAQFKTGHVTVLVA FT TNVAARGIHVDNLDLVVNVDPPSDHKDYLHRGGRTARAGESGSVVTLVTPNQRRAMTRL FT MTTAGIVPQTTPVRSGTEALHRVTGAQAPSGIPVVVTAPVAERAERGATSRGRRRPAPA FT TRRGSVRRSVTDAAA" FT misc_feature 36368..37003 FT /note="Pfam match to entry PF00270 DEAD, DEAD/DEAH box FT helicase, score 192.10, E-value 8.3e-60" FT misc_feature 36445..36455 FT /note="possible cold-shock box. E. coli cold shock FT box(5'-TGACGTACAGA-3'); Anabaena cold shock box, FT 5'-TGACAGGCCGA-3'" FT misc_feature 36461..36484 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 37088..37333 FT /note="Pfam match to entry PF00271 helicase_C, Helicases FT conserved C-terminal domain, score 105.10, E-value 1.4e-27" FT misc_feature 37130..37153 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 37653..37657 FT CDS 37664..37975 FT /transl_table=11 FT /gene="SCO4686" FT /gene_synonym="SCD31.11" FT /product="conserved hypothetical protein SCD31.11" FT /note="SCD31.11, hypothetical protein, len: 103 aa; similar FT to TR:O54115 (EMBL:AL021529) Streptomyces coelicolor FT hypothetical 14.3 kD protein SC10A5.24c, 134 aa; fasta FT scores: opt: 353 z-score: 464.3 E(): 2e-18; 75.3% identity FT in 73 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9L0F6" FT /protein_id="CAB82054.1" FT /translation="MTLLQTHPRPTDTDAGHRTVADAVDAAGPQVWDDMTVEVALSVMA FT AARTGHLVVCDQDGQHTGLVTRARLTAVRNGSAYTDRVRLRDVTDELGNALGVPVLSR" FT CDS complement(38011..38370) FT /transl_table=11 FT /gene="SCO4687" FT /gene_synonym="SCD31.12c" FT /product="hypothetical protein SCD31.12c" FT /note="SCD31.12c, unknown, len: 119 aa" FT /db_xref="UniProtKB/TrEMBL:Q9L0F5" FT /protein_id="CAB82055.1" FT /translation="MSKPDELLIDIAALVESGQSSRMSLTVVTHGAVITGRLAPERVWR FT QRVSEVLTDSADLGDFSAVFEAPAKHDGPPTHLHFHVARILQGTMGIPETGGMYRVALD FT DVSAWTVGDFSYSDH" FT CDS complement(38422..38778) FT /transl_table=11 FT /gene="SCO4688" FT /gene_synonym="SCD31.13c" FT /product="conserved hypothetical protein SCD31.13c" FT /note="SCD31.13c, hypothetical protein, len: 118 aa; highly FT similar to TR:O54113 (EMBL:AL021529) Streptomyces FT coelicolor hypothetical 12.6 kD protein SC10A5.22, 112 aa; FT fasta scores: opt: 579 z-score: 753.8 E(): 0; 87.0% FT identity in 100 aa overlap" FT /db_xref="GOA:Q9L0F4" FT /db_xref="InterPro:IPR000551" FT /db_xref="UniProtKB/TrEMBL:Q9L0F4" FT /protein_id="CAB82056.1" FT /translation="MTAGTPLGRIDDDDYPAYTMGRAAEMLGTTPAFLRALGEARLITP FT LRSEGGHRRYSRYQLRIAARAREMVDQGTAIEAACRIIILEDQLEEAQRINEELRSGGA FT EASGDSSGSGRPAR" FT RBS complement(38784..38788) FT CDS 39278..39610 FT /transl_table=11 FT /gene="SCO4689" FT /gene_synonym="SCD31.14" FT /product="hypothetical protein SCD31.14" FT /note="SCD31.14, hypothetical protein, len: 110 aa; similar FT to TR:O06194 (EMBL:Z95387) Mycobacterium tuberculosis FT hypothetical 12.3 kD protein MTCY1A10.14, 117 aa; fasta FT scores: opt: 407 z-score: 548.1 E(): 4.2e-23; 56.0% FT identity in 109 aa overlap" FT /db_xref="InterPro:IPR013096" FT /db_xref="UniProtKB/TrEMBL:Q9L0F3" FT /protein_id="CAB82057.1" FT /translation="MQKLSLDALAREHLERAAAGSHGRSATTVHGGHELVLRQTLLALT FT AGTTLAEHENPGEATVQVLRGRVRLTSGDTSWDGRAGDLILIPPARHSLEALEDSAVLL FT TVAKTG" FT CDS 39684..39926 FT /transl_table=11 FT /gene="SCO4690" FT /gene_synonym="SCD31.15" FT /product="putative membrane protein" FT /note="SCD31.15, possible membrane protein, len: 80 aa; FT similar to N-terminal region of TR:Q9WX28 (EMBL:AL079345) FT Streptomyces coelicolor putative membrane protein SCE68.03, FT 441 aa; fasta scores: opt: 237 z-score: 347.7 E(): 6.2e-12; FT 52.9% identity in 68 aa overlap. Contains possible FT hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9L0F2" FT /protein_id="CAB82058.1" FT /translation="MPNPLPSACALFSCWGRTPRQFFVSRVIRLYPAYWFAVLFTTAAL FT IAVPGVWERLRLREVLLDLTMLQSGSGVPDVDGVY" FT CDS 39978..40571 FT /transl_table=11 FT /gene="SCO4691" FT /gene_synonym="SCD31.16" FT /product="putative membrane protein" FT /note="SCD31.16, possible membrane protein, len: 197 aa; FT similar to C-terminal region of TR:Q9WX28 (EMBL:AL079345) FT Streptomyces coelicolor putative membrane protein SCE68.03, FT 441 aa; fasta scores: opt: 495 z-score: 618.7 E(): 5e-27; FT 41.5% identity in 205 aa overlap. Contains possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9L0F1" FT /db_xref="InterPro:IPR002656" FT /db_xref="UniProtKB/TrEMBL:Q9L0F1" FT /protein_id="CAB82059.1" FT /translation="MGLTYRRVVVLCRVWGAVAMLAPVARLPLLELVANPDGAWYSIAG FT LALHLVHRFGQDLLLRGILAMAWLMGQLEPGNRIEDVERVSGRRGSGAVFTVFLLFMVA FT VPLGYTDRIRWKWLVTAGAMTYPLYLVHCAAGTALIARLRDTMDARLPIAVLVTGFLLL FT SYLIHRFVERPLSRLLKRGLDTSFARLRNADHRP" FT RBS 40647..40651 FT CDS 40663..41310 FT /transl_table=11 FT /gene="SCO4692" FT /gene_synonym="SCD31.17" FT /product="conserved hypothetical protein SCD31.17" FT /note="SCD31.17, hypothetical protein, len: 215 aa; similar FT to TR:Q9F3G1 (EMBL:AL392175) Streptomyces coelicolor FT hypothetical protein 2SCD4.10c, 201 aa; fasta scores: opt: FT 776 Z-score: 867.6 E(): 1.1e-40; 59.000% identity in 200 aa FT overlap" FT /db_xref="UniProtKB/TrEMBL:Q9L0F0" FT /protein_id="CAB82060.1" FT /translation="MARYTEALTVERGGFRIKVPESWWEFDVRPESRDDSIRRMVDDRI FT RRYPELKPSRAAYVTFLQKAASDAWKSGALYCGCMAESFGGDTPITGSVTVSLIGGRTS FT TGDPLPTDPGAIAAQLAVKEAKKPGDSWRKVTTVDIPGVGPAARTRGVEDIPVPDDALN FT RTVRAVLMQTYIPVPGQEGKVALVAGSSQVLDLADSFFDIFDAITSTFRFAG" FT RBS 41400..41403 FT CDS 41407..41667 FT /transl_table=11 FT /gene="SCO4693" FT /gene_synonym="SCD31.18" FT /product="putative membrane protein" FT /note="SCD31.18, putative membrane protein, len: 86 aa. FT Contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9L0E9" FT /protein_id="CAB82061.1" FT /translation="MVSRPRRRRPAASSTRETIQPPGTGQLVVWMVTVTLLVAVVGSLA FT NSGMALVGLLVLLPAAAAAHARCGRRLWSAPGPLSSAPPLF" FT CDS 41700..41942 FT /transl_table=11 FT /gene="SCO4694" FT /gene_synonym="SCD31.19" FT /product="hypothetical protein SCD31.19" FT /note="SCD31.19, hypothetical protein, len: 80 aa; similar FT to part of TR:O54162 (EMBL:AL021411) Streptomyces FT coelicolor hypothetical 40.9 kD protein SC7H1.03c, 391 aa; FT fasta scores: opt: 301 z-score: 411.2 E(): 1.8e-15; 58.8% FT identity in 80 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9L0E8" FT /protein_id="CAB82062.1" FT /translation="MLLLVLTACLIAASLYARRRRINSERSMVRLHSAAVAIQRQILRP FT LPLRTDDVLVDGAYEPVQEDRLVGGDIYDVVESAW" FT CDS 41988..42533 FT /transl_table=11 FT /gene="SCO4695" FT /gene_synonym="SCD31.20" FT /product="hypothetical protein SCD31.20" FT /note="SCD31.20, hypothetical protein, len: 181 aa; similar FT to C-terminal part of many hypothetical proteins, e.g. FT TR:O54162 (EMBL:AL021411) Streptomyces coelicolor FT hypothetical 40.9 kD protein SC7H1.03c, 391 aa; fasta FT scores: opt: 594 z-score: 691.0 E(): 4.7e-31; 53.5% FT identity in 185 aa overlap" FT /db_xref="GOA:Q9L0E7" FT /db_xref="InterPro:IPR010822" FT /db_xref="UniProtKB/TrEMBL:Q9L0E7" FT /protein_id="CAB82063.1" FT /translation="MGAAFAVLGSFREAAHREPTLTGLVDALDASVVRHNSYVARRGDD FT ERFVTVLILNIDDARNEVQAINCGHVPPHLLDADSVITPPLDSGAPLGLAALAAEPATP FT GRFAFPGGTALLLTTDGLTESRAADGAFYPLDERLAGPGDLPRALNEDAHAYAGKAAPH FT DDVAILTVRRPHRSCTLS" FT CDS 42564..43031 FT /transl_table=11 FT /gene="SCO4696" FT /gene_synonym="SCD31.21" FT /product="hypothetical protein SCD31.21" FT /note="SCD31.21, unknown, len: 155 aa" FT /db_xref="UniProtKB/TrEMBL:Q9L0E6" FT /protein_id="CAB82064.1" FT /translation="MTAQWNWETGERLLALNDPKEWDAAFDRGERGLGTAAIGLAFNCP FT LEEASPRIVRAMGLPDPAQRGFAFTAAGTAARLNRALTPELYAALRAEGPGRRSIAVNA FT IGDTLTFVPFRRLPTWLKCWRVVSTVRNKLDAWRLTFSYAVTDAWKAVRRR" FT CDS 43159..44973 FT /transl_table=11 FT /gene="SCO4697" FT /gene_synonym="SCD31.22" FT /product="putative integral membrane protein" FT /note="SCD31.22, possible integral membrane protein, len: FT 604 aa; N-terminal region similar to TR:Q9XD98 FT (EMBL:AF106004) Streptomyces coelicolor hypothetical 27.5 FT kD protein, 249 aa; fasta scores: opt: 953 z-score: 1009.5 FT E(): 0; 58.7% identity in 235 aa overlap and C-terminal FT region highly similar to C-terminal region of TR:O86757 FT (EMBL:AL031035) Streptomyces coelicolor hypothetical 28.2 FT kD protein SC6A9.25, 254 aa; fasta scores: opt: 309 FT z-score: 332.3 E(): 4.4e-11; 92.0% identity in 50 aa FT overlap. Contains PS00017 ATP/GTP-binding site motif A FT (P-loop), a possible hydrophobic membrane spanning region FT and a possible coiled-coil region at aprox residues FT 170..210" FT /db_xref="UniProtKB/TrEMBL:Q9L0E5" FT /protein_id="CAB82065.1" FT /translation="MVGHRPSDWHVLDLEKDPTPGDPQRVRTLAKTLHDFADDVSEALR FT LVKGMAGESTLAEWAGKSATVFKEEFDGVPKNLKKLEKSYGMCGDALADFWPKLERAQA FT LADKALIKAREARDDLTSGQSKLSSADSWVTRASKEADKYKDDPTGSKSDADKPDEAKV FT RAATRDVQHAKTAHANAQSAVNDAQSALDAAKKMAEDARKMRDDAAREAKNKIDEASDA FT GIQNRSWWEDVGDWFSDNWDTIVAVCKVVVAVVGIIAMVIGGPILGAIVLVAALVVLAD FT TLYKYSKGQASLWDVGLAALDCVPGMKGLTSLGGLAKGLKALGKTGLKGMAKAARGGMG FT KLRRQAQLMAERRCKSDPVDVITGDMVASAVDVELLGAHPLTFVRHYCSSFRGGRWFGP FT SWGSVLDERLLLDRDGVRLITADGMVLQYPVPESDAAVLPVMGPKWPLVWSGGPGGDMQ FT VRRPGDGETYHFRTLPGMPPAELRLTGVTDRNGNSIALEYEENGNPRAVVRKDGYRVGI FT EVSDGHVTALRLESDSTLPVLCRYRYDQHGNLSEIYNSSAQPLVVLSRDVGDTRAGFLK FT WVRASRFGVDCDISTEFRRPSWSTVMPR" FT misc_feature 44113..44136 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 44835..45905 FT /note="insertion element IS1652" FT repeat_region 44836..44878 FT /note="32/43 bp inverted repeat 15099 FT CTAGTTGTGTTGTCCCGGGACGTTGGTGACACGCGTGCTGGG 15141" FT CDS 44886..45905 FT /transl_table=11 FT /gene="SCO4698" FT /gene_synonym="SCD31.23" FT /product="putative insertion element IS1652 transposase" FT /note="SCD31.23, probable insertion element IS1652 FT transposase, len: 339 aa; identical to TR:CAB71807 FT (EMBL:AL138662) Streptomyces coelicolor putative FT transposase SC8E4A.02, 339 aa and highly similar to various FT other Streptomyces coelicolor transposases" FT /db_xref="GOA:Q9L0E4" FT /db_xref="InterPro:IPR001584" FT /db_xref="UniProtKB/TrEMBL:Q9L0E4" FT /protein_id="CAB82066.1" FT /translation="MGEGLQVRCGLRHLHRVQEALVVHRNAPLTETGRLRLARCVVEDG FT WPVRRAAERFQVSHTTASRWARRYRQLGVTGMSDRSSRPHHQPRRTAAAVEEHVLRLRR FT EHRIGPLRLAVRCGIAASTAHRILVRHGLPPLAALDRATGEPVRRYERARPGELVHIDV FT KKLGRIPDGGGHKTLGRAEGHRSRTNGAGWAYLHTALDDHSRIAYTEDLPDETAPTCAA FT FLVRATAYFASLGIRIERVLTDNAWAYSKNTWRNTCRDLDISPRWTRPWRPQTNGKVER FT FHRTLLDEWAYQKPYTSDHERREAFTHWLHWYNYHRPHTGIGGHTPASRGTNLSEQHI" FT repeat_region 45863..45905 FT /note="32/43 bp inverted repeat 16126 FT ACCCGCCAGCCGCGGCACCAACCTCTCCGAACAACACATCTAG 16168" FT CDS 45905..48688 FT /transl_table=11 FT /gene="SCO4699" FT /gene_synonym="SCD31.24" FT /product="putative Rhs protein" FT /note="SCD31.24, possible Rhs protein, len: 927 aa; similar FT to C-terminal domain of SW:RHSB_ECOLI (EMBL:L02370) FT Escherichia coli RhsB protein precursor, 1411 aa; fasta FT scores: opt: 510 z-score: 568.8 E(): 3e-24; 26.4% identity FT in 954 aa overlap" FT /db_xref="InterPro:IPR006530" FT /db_xref="UniProtKB/TrEMBL:Q9L0E3" FT /protein_id="CAB82067.1" FT /translation="MLSYDREHRIVGWRDRNGTEYRYEYDAHGRCVRTIGSDGYQSGTF FT RYDPAAGETVHVDSLGHATTFRYNRDLRITAEINALGNSTATEWDEDGRVLTETDALGR FT TTRYTYDAQDNLRTVIRPDGSHVTAEHGVLGLPERVVEADGSQWSFEYDTAGNLLSITD FT PANATARYTYGESGRLLAATNALGAEEAYAYDSFGRVVSHFDALGAETKFTYDSFGRME FT STTDSLGHVTRYGWTLEGLMAWRTSSDGAREHWTYDGEGNETEHHDAVGGVTTSQYTHF FT GLLASRTQPDGARLSFRHDTELRLTSVTDARSREWSYTYDAVGNLVGERDFFGRALEYA FT YDAADQLVTRTNALGRSTHYRHDLMGNVIEQRSGDGVARYSYDALGRMARAENADSVVI FT LERDPVGRIVAESCNGRTLRNKYDALGRRIHRHTPGGAFSVWEYDAADRPTALHTGSQS FT LTVRYDAAGRETERRTGPMAMAQRWDGYDRLVEQRLLDVHKEQFALLRQYSYRADDHLV FT EVADSFAGRRRFELDAGTHVTAVRADHWSEQYAYDPAGDVSHGDWPLSAAQGDARSAVG FT DRGEGSLGVRRAGRTTYEHDAQGRMTRRVTRALSGSRRVWEYAWNDQDQLREVVTPDGA FT RWQYLYDGLGRRIAKQLMGDDGGSRERVDFTWDGTDLAEQASATEDRVVSWDWSPHTGD FT PLVQTERPCGPELSQREVDTRFYAIVTDLVGAPTELVSPDGDIGWRLRTTLWGLPVDGS FT GGSTDCPLRFPGQYHDPETGLHYNYFRYYDPGLGRYCSLDPLGLAGGPNPAWYTPNPTA FT WIDPFGLALCRKRPRLETGDLKKGWLHIESRHITGTNPSTKHADMLPPGTTREQVHAAA FT RKAVRNGTRISDPGRRIQNFQKRMKVNGMYARFQVTVDSHDGNNIITFFPVDKSAV" FT repeat_region 45956..46003 FT /note="degenerate repeat unit GxxxRYxYDAxxxR" FT repeat_region 46211..46255 FT /note="degenerate repeat unit GxxxRYxYDAxxxR" FT repeat_region 47024..47065 FT /note="degenerate repeat unit GxxxRYxYDAxxxR" FT CDS 48709..49158 FT /transl_table=11 FT /gene="SCO4700" FT /gene_synonym="SCD31.25" FT /product="hypothetical protein SCD31.25" FT /note="SCD31.25, unknown, len: 149 aa" FT /db_xref="UniProtKB/TrEMBL:Q9L0E2" FT /protein_id="CAB82068.1" FT /translation="MKFEFSLDENETPPPSGFDLGHIAVWGSDGAATTRDRDPGGGAMV FT YLTVTSLLDGLRTFLSGKSRSYESTAVDSSFSLTFTRGRDGSIETRCGGALIDRSPVAG FT VAAAVHAAAKRFADAHLEQLPPDDAGREDLEHALADFERFMGRPR" FT CDS 49659..49967 FT /transl_table=11 FT /gene="SCO4701" FT /gene_synonym="rpsJ" FT /gene_synonym="SCD31.26" FT /product="30S ribosomal protein S10" FT /note="SCD31.26, rpsJ, 30S ribosomal protein S10, len: 102 FT aa; highly similar to SW:RS10_ECOLI (EMBL:V00344) FT Escherichia coli 30S ribosomal protein S10 RpsJ, 103 aa; FT fasta scores: opt: 428 z-score: 571.1 E(): 2.2e-24; 60.8% FT identity in 102 aa overlap. Contains Pfam match to entry FT PF00338 Ribosomal_S10, Ribosomal protein S10p/S20e and FT match to Prosite entry PS00361 Ribosomal protein S10 FT signature" FT /db_xref="GOA:P66337" FT /db_xref="HSSP:1J5E" FT /db_xref="InterPro:IPR018268" FT /db_xref="UniProtKB/Swiss-Prot:P66337" FT /protein_id="CAB82069.1" FT /translation="MAGQKIRIRLKAYDHEVIDSSAKKIVETVTRTGASVAGPVPLPTE FT KNVYCVIKSPHKYKDSREHFEMRTHKRLIDILDPTPKTVDSLMRLDLPAGVDIEIKL" FT misc_feature 49671..49958 FT /note="Pfam match to entry PF00338 Ribosomal_S10, Ribosomal FT protein S10p/S20e, score 221.30, E-value 1.4e-62" FT misc_feature 49743..49790 FT /note="PS00361 Ribosomal protein S10 signature" FT CDS 49984..50628 FT /transl_table=11 FT /gene="SCO4702" FT /gene_synonym="rplC" FT /gene_synonym="SCD31.27" FT /product="50S ribosomal protein L3" FT /note="SCD31.27, rplC, 50S ribosomal protein L3, len: 214 FT aa; highly similar to SW:RL3_ECOLI (EMBL:V00344) FT Escherichia coli 50S ribosomal protein L3, RplC, 209 aa; FT fasta scores: opt: 683 z-score: 783.3 E(): 0; 51.9% FT identity in 206 aa overlap. Contains Pfam match to entry FT PF00297 Ribosomal_L3, Ribosomal protein L3 and match to FT Prosite entry PS00474 Ribosomal protein L3 signature" FT /db_xref="GOA:Q9L0E0" FT /db_xref="InterPro:IPR019926" FT /db_xref="UniProtKB/Swiss-Prot:Q9L0E0" FT /protein_id="CAB82070.1" FT /translation="MTKQIKGILGEKLGMTQVWDENNRVVPVTVVKAGPNVVTQVRTND FT VDGYESVQIAFGEIDPRKVNKPLKGHFAKADVTPRRHLVEIRTAAASEYTLGQEITAEA FT FESGVKVDVTAKSKGKGFAGVMKRHNFKGGKASHGAHRVHRMPGSIGGCATPGRVFKGM FT RMAGRMGNERVTTQNLTVHAVDAEKGLLLIKGAVPGPNGGLVLVRTAAKGA" FT misc_feature 50017..50607 FT /note="Pfam match to entry PF00297 Ribosomal_L3, Ribosomal FT protein L3, score 280.20, E-value 2.6e-80" FT misc_feature 50296..50367 FT /note="PS00474 Ribosomal protein L3 signature" FT RBS 50627..50630 FT CDS 50637..51296 FT /transl_table=11 FT /gene="SCO4703" FT /gene_synonym="rplD" FT /gene_synonym="SCD31.28" FT /product="50S ribosomal protein L4" FT /note="SCD31.28, rplD, 50S ribosomal protein L4, len: 219 FT aa; highly similar to SW:RL4_BACST (EMBL:X67014) Bacillus FT stearothermophilus 50S ribosomal protein L4 RplD, 207 aa; FT fasta scores: opt: 563 z-score: 669.3 E(): 7.5e-30; 44.1% FT identity in 202 aa overlap. Contains Pfam match to entry FT PF00573 Ribosomal_L4, Ribosomal protein L4/L1 family" FT /db_xref="GOA:Q9L0D9" FT /db_xref="InterPro:IPR013005" FT /db_xref="UniProtKB/Swiss-Prot:Q9L0D9" FT /protein_id="CAB82071.1" FT /translation="MSTVDILSPAGEKTGSVELPAEIFGVEKISIPLIHQVVVAQNAAA FT RQGTHKTKRRGEVRGGGKKPYRQKGTGRARQGSTRAPQFAGGGVVHGPQPRDYSQRTPK FT KMKAAALRHALTDRARHNRIHVVTGVIEGENPSTKAARTLFGKISERKNLLLVVDRADE FT AAWLSARNLPQIHILEPGQLNTYDVLVSDDVVFTQAAFESFVSGPNKAVDTEGSEA" FT misc_feature 50682..51257 FT /note="Pfam match to entry PF00573 Ribosomal_L4, Ribosomal FT protein L4/L1 family, score 219.20, E-value 6e-62" FT RBS 51283..51286 FT CDS 51296..51715 FT /transl_table=11 FT /gene="SCO4704" FT /gene_synonym="rplW" FT /gene_synonym="SCD31.29" FT /product="50S ribosomal protein L23" FT /note="SCD31.29, rplW, 50S ribosomal protein L23, len: 139 FT aa; highly similar to SW:RL23_BACSU (EMBL:D50302) Bacillus FT subtilis 50S ribosomal protein L23 RplW, 95 aa; fasta FT scores: opt: 241 z-score: 308.8 E(): 9e-10; 41.8% identity FT in 91 aa overlap. Contains Pfam match to entry PF00276 FT Ribosomal_L23, Ribosomal protein L23 and match to Prosite FT entry PS00050 Ribosomal protein L23 signature" FT /db_xref="GOA:Q9L0D8" FT /db_xref="HSSP:1N88" FT /db_xref="InterPro:IPR001014" FT /db_xref="UniProtKB/TrEMBL:Q9L0D8" FT /protein_id="CAB82072.1" FT /translation="MATRHPSIASKAAKAAKAARVAKARRHEAEGKNTVVTPASKAFTD FT PRDVLLKPVVSEKSYALLDENKYTFVVAPGSNKTQIKEAVQAVFSVKVTGVNTINRQGK FT RKRTRTGFGKRADSKRAIVTLAEGDRIDIFGGPTS" FT misc_feature 51434..51706 FT /note="Pfam match to entry PF00276 Ribosomal_L23, Ribosomal FT protein L23, score 117.70, E-value 9.2e-34" FT misc_feature 51650..51697 FT /note="PS00050 Ribosomal protein L23 signature" FT RBS 51744..51748 FT CDS 51756..52592 FT /transl_table=11 FT /gene="SCO4705" FT /gene_synonym="rplB" FT /gene_synonym="SCD31.30" FT /product="50S ribosomal protein L2" FT /note="SCD31.30, rplB, 50S ribosomal protein L2, len: 278 FT aa; highly similar to SW:RL2_BACSU (EMBL:D50302) Bacillus FT subtilis 50S ribosomal protein L2 RplB, 276 aa; fasta FT scores: opt: 1206 z-score: 1384.9 E(): 0; 62.8% identity in FT 277 aa overlap. Contains Pfam match to entry PF00181 FT Ribosomal_L2, Ribosomal Proteins L2 and match to Prosite FT entry PS00467 Ribosomal protein L2 signature" FT /db_xref="GOA:Q9L0D7" FT /db_xref="HSSP:1RL2" FT /db_xref="InterPro:IPR014722" FT /db_xref="UniProtKB/Swiss-Prot:Q9L0D7" FT /protein_id="CAB82073.1" FT /translation="MGIRKYKPTTPGRRGSSVADFVEVTRSTPEKSLVRPLHSKGGRNN FT AGRVTVRHQGGGHKRAYRVIDFRRHDKDGVPAKVAHIEYDPNRTARIALLHYADGEKRY FT ILAPRNLQQGDRVENGPGADIKPGNNLALRNIPVGTTIHAIELRPGGGAKFARSAGASV FT QLLAKEGTMAHLRMPSGEIRLVDQRCRATVGEVGNAEQSNINWGKAGRKRWLGVRPTVR FT GVVMNPVDHPHGGGEGRTSGGRHPVSPWGKKEGRTRSPKKASNKYIVRRRKTNKKR" FT misc_feature 51879..52577 FT /note="Pfam match to entry PF00181 Ribosomal_L2, Ribosomal FT Proteins L2, score 412.90, E-value 3e-120" FT misc_feature 52410..52445 FT /note="PS00467 Ribosomal protein L2 signature" FT CDS 52605..52886 FT /transl_table=11 FT /gene="SCO4706" FT /gene_synonym="rpsS" FT /gene_synonym="SCD31.31" FT /product="30S ribosomal protein S19" FT /note="SCD31.31, rpsS, 30S ribosomal protein S19, len: 93 FT aa; highly similar to SW:RS19_BACST (EMBL:X54994) Bacillus FT stearothermophilus 30S ribosomal protein S19 RpsS, 91 aa; FT fasta scores: opt: 448 z-score: 642.9 E(): 2.2e-28; 67.8% FT identity in 90 aa overlap. Contains Pfam match to entry FT PF00203 Ribosomal_S19, Ribosomal protein S19 and match to FT Prosite entry PS00323 Ribosomal protein S19 signature" FT /db_xref="GOA:Q9L0D6" FT /db_xref="HSSP:1FJG" FT /db_xref="InterPro:IPR005732" FT /db_xref="UniProtKB/Swiss-Prot:Q9L0D6" FT /protein_id="CAB82074.1" FT /translation="MPRSLKKGPFVDDHLIKKVDTQNEAGTKNVIKTWSRRSMIVPAML FT GHTIAVHNGKTHIPVFVTESMVGHKLGEFSPTRTFRGHVKDDRKSKRR" FT misc_feature 52611..52853 FT /note="Pfam match to entry PF00203 Ribosomal_S19, Ribosomal FT protein S19, score 179.50, E-value 1.9e-51" FT misc_feature 52761..52835 FT /note="PS00323 Ribosomal protein S19 signature" FT CDS 52899..53276 FT /transl_table=11 FT /gene="SCO4707" FT /gene_synonym="rplV" FT /gene_synonym="SCD31.32" FT /product="50S ribosomal protein L22" FT /note="SCD31.32, rplV, 50S ribosomal protein L22, len: 125 FT aa; highly similar to SW:RL22_BACST (EMBL:X54994) Bacillus FT stearothermophilus 50S ribosomal protein L22, RplV, 113 aa; FT fasta scores: opt: 441 z-score: 566.9 E(): 3.8e-24; 64.0% FT identity in 114 aa overlap. Contains Pfam match to entry FT PF00237 Ribosomal_L22, Ribosomal protein L22 and match to FT Prosite entry PS00464 Ribosomal protein L22 signature" FT /db_xref="GOA:Q9L0D5" FT /db_xref="HSSP:1BXE" FT /db_xref="InterPro:IPR005727" FT /db_xref="UniProtKB/Swiss-Prot:Q9L0D5" FT /protein_id="CAB82075.1" FT /translation="MTMTNTEGTTMEARAQARYIRVTPMKARRVVDLIRGMDATEAQAV FT LRFAPQAASVPVGKVLDSAIANAAHNYDHTDADSLFISEAYVDEGPTLKRFRPRAQGRA FT YRIRKRTSHITVVVSSKEGTR" FT misc_feature 52941..53258 FT /note="Pfam match to entry PF00237 Ribosomal_L22, Ribosomal FT protein L22, score 190.10, E-value 3.4e-53" FT misc_feature 53178..53252 FT /note="PS00464 Ribosomal protein L22 signature" FT misc_feature 53276..53458 FT /note="Pfam match to entry PF00417 Ribosomal_S3_N, FT Ribosomal protein S3, N-terminal domain., score 89.90, FT E-value 8.7e-28" FT CDS 53276..54109 FT /transl_table=11 FT /gene="SCO4708" FT /gene_synonym="rpsC" FT /gene_synonym="SCD31.33" FT /product="30S ribosomal protein S3" FT /note="SCD31.33, rpsC, 30S ribosomal protein S3, len: 277 FT aa; hihgly similar to SW:RS3_BACSU (EMBL:D50302) Bacillus FT subtilis 30S ribosomal protein S3 RpsC, 217 aa; fasta FT scores: opt: 801 z-score: 820.5 E(): 0; 55.1% identity in FT 205 aa overlap. Contains Pfam matches to entries PF00417 FT Ribosomal_S3_N, Ribosomal protein S3, N-terminal domain, FT PF00013 KH-domain, KH domain and PF00189 Ribosomal_S3_C, FT Ribosomal protein S3, C-terminal domain and matches to FT Prosite entries PS00050 Ribosomal protein L23 signature and FT PS00548 Ribosomal protein S3 signature" FT /db_xref="GOA:Q9L0D4" FT /db_xref="InterPro:IPR008282" FT /db_xref="UniProtKB/Swiss-Prot:Q9L0D4" FT /protein_id="CAB82076.1" FT /translation="MGQKVNPHGFRLGITTDFKSRWYADKLYKDYVKEDVAIRRMLTSG FT MERAGISKVEIERTRDRVRVDIHTARPGIVIGRRGAEADKIRGQLEKLTGKQVQLNILE FT VKSPETDAQLVAQAVAEQLSSRVSFRRAMRKSMQGTMKAGAKGIKIQCGGRLGGAEMSR FT SEFYREGRVPLHTLRANVDYGFFEAKTTFGRIGVKVWIYKGDVKNIAEVRAENAAARAG FT NRPARGGGNDRPARGGRGGERRGRKPQQQSAPAAEAPKAEAPAAAAPAESTGTEA" FT misc_feature 53465..53608 FT /note="Pfam match to entry PF00013 KH-domain, KH domain, FT score 23.30, E-value 1.2e-05" FT misc_feature 53468..53515 FT /note="PS00050 Ribosomal protein L23 signature" FT misc_feature 53627..53878 FT /note="Pfam match to entry PF00189 Ribosomal_S3_C, FT Ribosomal protein S3, C-terminal domain., score 152.70, FT E-value 7.1e-47" FT misc_feature 53759..53863 FT /note="PS00548 Ribosomal protein S3 signature" FT RBS 54100..54104 FT misc_feature 54115..54510 FT /note="Pfam match to entry PF00252 Ribosomal_L16, Ribosomal FT protein L16, score 245.50, E-value 7.6e-71" FT CDS 54115..54534 FT /transl_table=11 FT /gene="SCO4709" FT /gene_synonym="rplP" FT /gene_synonym="SCD31.34" FT /product="50S ribosomal protein L16" FT /note="SCD31.34, rplP, 50S ribosomal protein L16, len: 139 FT aa; highly similar to SW:RL16_BACSU (EMBL:D50302) Bacillus FT subtilis 50S ribosomal protein L16 RplP, 144 aa; fasta FT scores: opt: 625 z-score: 768.2 E(): 0; 63.8% identity in FT 141 aa overlap. Contains Pfam match to entry PF00252 FT Ribosomal_L16, Ribosomal protein L16 and match to Prosite FT entry PS00701 Ribosomal protein L16 signature 2" FT /db_xref="GOA:Q9L0D3" FT /db_xref="InterPro:IPR000114" FT /db_xref="UniProtKB/Swiss-Prot:Q9L0D3" FT /protein_id="CAB82077.1" FT /translation="MLIPRRVKHRKQHHPKRRGMAKGGTQVAFGEYGIQALTPAYVTNR FT QIEAARIAMTRHIKRGGKVWINIYPDRPLTKKPAETRMGSGKGSPEWWIANVHPGRVMF FT ELSYPNEKIAREALTRAAHKLPMKCRIVKREAGEA" FT misc_feature 54358..54393 FT /note="PS00701 Ribosomal protein L16 signature 2" FT CDS 54534..54758 FT /transl_table=11 FT /gene="SCO4710" FT /gene_synonym="rpmC" FT /gene_synonym="SCD31.35" FT /product="50S ribosomal protein L29" FT /note="SCD31.35, rpmC, 50S ribosomal protein L29, len: 74 FT aa; highly similar to SW:RL29_BACST (PIR:A02825) Bacillus FT stearothermophilus 50S ribosomal protein L29 RpmC, 66 aa; FT fasta scores: opt: 244 z-score: 361.6 E(): 1e-12; 63.9% FT identity in 61 aa overlap. Contains Pfam match to entry FT PF00831 Ribosomal_L29, Ribosomal L29 protein and match to FT Prosite entry PS00323 Ribosomal protein S19 signature" FT /db_xref="GOA:Q9L0D2" FT /db_xref="InterPro:IPR018254" FT /db_xref="UniProtKB/Swiss-Prot:Q9L0D2" FT /protein_id="CAB82078.1" FT /translation="MSAGTKASELRELGNEELLAKLREAKEELFNLRFQAATGQLENHG FT RLKAVRKDIARIYTLMRERELGIETVESA" FT misc_feature 54552..54740 FT /note="Pfam match to entry PF00831 Ribosomal_L29, Ribosomal FT L29 protein, score 106.60, E-value 4.7e-28" FT misc_feature 54579..54653 FT /note="PS00323 Ribosomal protein S19 signature" FT RBS 54746..54751 FT CDS 54758..55045 FT /transl_table=11 FT /gene="SCO4711" FT /gene_synonym="rpsQ" FT /gene_synonym="SCD31.36" FT /product="30S ribosomal protein S17" FT /note="SCD31.36, rpsQ, 30S ribosomal protein S17, len: 95 FT aa; highly similar to SW:RS17_BACSU (EMBL:X15664) Bacillus FT subtilis 30S ribosomal protein S17 RpsQ, 86 aa; fasta FT scores: opt: 316 z-score: 456.1 E(): 5.7e-18; 61.7% FT identity in 81 aa overlap. Contains Pfam match to entry FT PF00366 Ribosomal_S17, Ribosomal protein S17 and match to FT Prosite entry PS00056 Ribosomal protein S17 signature" FT /db_xref="GOA:Q9L0D1" FT /db_xref="HSSP:1RIP" FT /db_xref="InterPro:IPR019979" FT /db_xref="UniProtKB/Swiss-Prot:Q9L0D1" FT /protein_id="CAB82079.1" FT /translation="MSESNVTEETKAARGFRKTRQGLVVSDKMDKTVVVAVEDRVTHAL FT YGKVIRRTEKLKAHDEQNAAGVGDRVLLMETRPLSATKRWRVVEVLEKAK" FT misc_feature 54821..55027 FT /note="Pfam match to entry PF00366 Ribosomal_S17, Ribosomal FT protein S17, score 127.50, E-value 1.2e-36" FT misc_feature 54959..54997 FT /note="PS00056 Ribosomal protein S17 signature" FT RBS 55143..55147 FT misc_feature 55153..55518 FT /note="Pfam match to entry PF00238 Ribosomal_L14, Ribosomal FT protein L14, score 263.20, E-value 3.5e-75" FT CDS 55153..55521 FT /transl_table=11 FT /gene="SCO4712" FT /gene_synonym="rplN" FT /gene_synonym="SCD31.37" FT /product="50S ribosomal protein L14" FT /note="SCD31.37, rplN, 50S ribosomal protein L14, len: 122 FT aa; highly similar to SW:RL14_BACST (PIR:A02789) Bacillus FT stearothermophilus 50S ribosomal protein L14 RplN, 122 aa; FT fasta scores: opt: 630 z-score: 783.7 E(): 0; 77.9% FT identity in 122 aa overlap. Contains Pfam match to entry FT PF00238 Ribosomal_L14, Ribosomal protein L14 and match to FT Prosite entry PS00049 Ribosomal protein L14 signature" FT /db_xref="GOA:Q9L0D0" FT /db_xref="HSSP:1WHI" FT /db_xref="InterPro:IPR019972" FT /db_xref="UniProtKB/Swiss-Prot:Q9L0D0" FT /protein_id="CAB82080.1" FT /translation="MIQQESRLRVADNTGAKEILTIRVLGGSGRRYAGIGDVIVATVKD FT AIPGGNVKKGDVVKAVIVRTVKERRRPDGSYIRFDENAAVILKNDGDPRGTRIFGPVGR FT ELREKKFMKIISLAPEVL" FT misc_feature 55330..55410 FT /note="PS00049 Ribosomal protein L14 signature" FT RBS 55509..55513 FT CDS 55524..55847 FT /transl_table=11 FT /gene="SCO4713" FT /gene_synonym="rplX" FT /gene_synonym="SCD31.38" FT /product="50S ribosomal protein L24" FT /note="SCD31.38, rplX, 50S ribosomal protein L24, len: 107 FT aa; highly similar to SW:RL24_BACSU (EMBL:X15664) Bacillus FT subtilis 50S ribosomal protein L24 RplX, 103 aa; fasta FT scores: opt: 390 z-score: 475.1 E(): 4.9e-19; 62.9% FT identity in 105 aa overlap. Contains Pfam match to entry FT PF00467 Ribosomal_L24, KOW motif and match to Prosite entry FT PS01108 Ribosomal protein L24 signature" FT /db_xref="GOA:Q9L0C9" FT /db_xref="InterPro:IPR005825" FT /db_xref="UniProtKB/Swiss-Prot:Q9L0C9" FT /protein_id="CAB82081.1" FT /translation="MKIKKGDLVQVITGKDKGKQGKVIAAFPREDRVLVEGVNRVKKHT FT KAGPTARGSQAGGIVTTEAPIHVSNVQLVVEKDGNKVVTRVGYRFDDEGNKVRVAKRTG FT EDI" FT misc_feature 55530..55709 FT /note="Pfam match to entry PF00467 Ribosomal_L24, KOW FT motif, score 94.20, E-value 2.7e-24" FT misc_feature 55539..55592 FT /note="PS01108 Ribosomal protein L24 signature" FT RBS 55836..55840 FT CDS 55847..56404 FT /transl_table=11 FT /gene="SCO4714" FT /gene_synonym="rplE" FT /gene_synonym="SCD31.39" FT /product="50S ribosomal protein L5" FT /note="SCD31.39, rplE, 50S ribosomal protein L5, len: 185 FT aa; highly similar to SW:RL5_ECOLI (EMBL:X01563) FT Escherichia coli 50S ribosomal protein L5 RplE, 178 aa; FT fasta scores: opt: 745 z-score: 920.9 E(): 0; 58.8% FT identity in 177 aa overlap. Contains Pfam matches to FT entries PF00281 Ribosomal_L5, Ribosomal protein L5 and FT PF00673 Ribosomal_L5_C, ribosomal L5P family C-terminus and FT match to Prosite entry PS00358 Ribosomal protein L5 FT signature" FT /db_xref="GOA:Q9L0C8" FT /db_xref="HSSP:1IQ4" FT /db_xref="InterPro:IPR002132" FT /db_xref="UniProtKB/Swiss-Prot:Q9L0C8" FT /protein_id="CAB82082.1" FT /translation="MATTTTPRLKTKYREEIAGKLREEFSYENVMQIPGLVKIVVNMGV FT GDAARDSKLIEGAIRDLTTITGQKPAVTKARKSIAQFKLREGQPIGAHVTLRGDRMWEF FT LDRTLSLALPRIRDFRGLSPKQFDGRGNYTFGLTEQVMFHEIDQDKIDRTRGMDITVVT FT TATNDAEGRALLRHLGFPFKEA" FT misc_feature 55931..56101 FT /note="Pfam match to entry PF00281 Ribosomal_L5, Ribosomal FT protein L5, score 117.00, E-value 3.4e-31" FT misc_feature 56030..56080 FT /note="PS00358 Ribosomal protein L5 signature" FT misc_feature 56111..56395 FT /note="Pfam match to entry PF00673 Ribosomal_L5_C, FT ribosomal L5P family C-terminus, score 194.30, E-value FT 2e-54" FT RBS 56395..56399 FT misc_feature 56410..56592 FT /note="Pfam match to entry PF00253 Ribosomal_S14, Ribosomal FT protein S14p/S29e, score 107.50, E-value 6.2e-32" FT CDS 56410..56595 FT /transl_table=11 FT /gene="SCO4715" FT /gene_synonym="rpsN" FT /gene_synonym="SCD31.40" FT /product="30S ribosomal protein S14" FT /note="SCD31.40, rpsN, 30S ribosomal protein S14, len: 61 FT aa; highly similar to SW:RS14_BACST Bacillus FT stearothermophilus 30S ribosomal protein S14 RpsN, 61 aa; FT fasta scores: opt: 335 z-score: 483.7 E(): 1.6e-19; 68.9% FT identity in 61 aa overlap. Contains Pfam match to entry FT PF00253 Ribosomal_S14, Ribosomal protein S14p/S29e and FT match to Prosite entry PS00527 Ribosomal protein S14 FT signature" FT /db_xref="GOA:P66417" FT /db_xref="InterPro:IPR018271" FT /db_xref="UniProtKB/Swiss-Prot:P66417" FT /protein_id="CAB82083.1" FT /translation="MAKKALIAKAARKPKFGVRGYTRCQRCGRPHSVYRKFGLCRVCLR FT EMAHRGELPGVTKSSW" FT misc_feature 56476..56544 FT /note="PS00527 Ribosomal protein S14 signature" FT RBS 56795..56799 FT CDS 56807..57205 FT /transl_table=11 FT /gene="SCO4716" FT /gene_synonym="rpsH" FT /gene_synonym="SCD31.42" FT /product="30S ribosomal protein S8" FT /note="SCD31.41, rpsH, 30S ribosomal protein S8, len: 147 FT aa; identical to C-terminal part of SW:RS8_STRCO FT (EMBL:X83011) Streptomyces coelicolor 30S ribosomal protein FT S8 RpsH (fragment), 121 aa and highly similar to FT SW:RS8_BACHD (EMBL:AB017508) Bacillus halodurans 30S FT ribosomal protein S8 RpsH, 131 aa; fasta scores: opt: 526 FT z-score: 661.3 E(): 2.1e-29; 61.8% identity in 131 aa FT overlap. Contains Pfam match to entry PF00410 Ribosomal_S8, FT Ribosomal protein S8" FT /db_xref="GOA:P49399" FT /db_xref="HSSP:1SEI" FT /db_xref="InterPro:IPR000630" FT /db_xref="UniProtKB/Swiss-Prot:P49399" FT /protein_id="CAB82084.1" FT /translation="MTMTDPIADMLTRLRNANSAYHDSVTMPASKIKSHIAEILQQEGF FT ITGWKTEDAEVGKNLTLELKFGPNRERSIAGIKRISKPGLRVYAKSTNLPKVLGGLGVA FT IISTSHGLLTDKQAGKKGVGGEVLAYVW" FT misc_feature 56819..57202 FT /note="Pfam match to entry PF00410 Ribosomal_S8, Ribosomal FT protein S8, score 238.30, E-value 4e-72" FT misc_feature 56840..61488 FT /note="previously sequenced fragment (EMBL:X83011)" FT RBS 57217..57222 FT CDS 57230..57769 FT /transl_table=11 FT /gene="SCO4717" FT /gene_synonym="rplF" FT /gene_synonym="SCD31.42" FT /product="50S ribosomal protein L6" FT /note="SCD31.42, rplF, 50S ribosomal protein L6, len: 179 FT aa; identical to previosuly sequenced SW:RL6_STRCO FT (EMBL:X83011) Streptomyces coelicolor 50S ribosomal protein FT L6 RplF, 179 aa. Contains Pfam match to entry PF00347 FT Ribosomal_L6, Ribosomal protein L6 and match to Prosite FT entry PS00525 Ribosomal protein L6 signature 1" FT /db_xref="GOA:P46786" FT /db_xref="HSSP:1C04" FT /db_xref="InterPro:IPR019906" FT /db_xref="UniProtKB/Swiss-Prot:P46786" FT /protein_id="CAB82085.1" FT /translation="MSRIGKLPIAVPAGVDVTIDGRTVSVKGPKGSLTHTVVAPIDIAK FT GEDGVLNVTRPNDERQSKALHGLSRTLVANMITGVTQGYVKKLEISGVGYRVLAKGSNL FT EFSLGYSHPILVEAPEGITFKVENPTHFSVEGIDKQKVGEVAANIRKLRKPDPYKAKGV FT KYEGEVIRRKVGKAGK" FT misc_feature 57260..57766 FT /note="Pfam match to entry PF00347 Ribosomal_L6, Ribosomal FT protein L6, score 327.80, E-value 1.2e-94" FT misc_feature 57692..57718 FT /note="PS00525 Ribosomal protein L6 signature 1" FT CDS 57773..58156 FT /transl_table=11 FT /gene="SCO4718" FT /gene_synonym="rplR" FT /gene_synonym="SCD31.43" FT /product="50S ribosomal protein L18" FT /note="SCD31.43, rplR, 50S ribosomal protein L18, len: 127 FT aa; identical to previously sequenced SW:RL18_STRCO FT (EMBL:X83011) Streptomyces coelicolor 50S ribosomal protein FT L18 RplR, 127 aa. Contains Pfam match to entry PF00861 FT Ribosomal_L18p, Ribosomal L18p/L5e family and match to FT Prosite entry PS00358 Ribosomal protein L5 signature" FT /db_xref="GOA:P46788" FT /db_xref="HSSP:1ILY" FT /db_xref="InterPro:IPR004389" FT /db_xref="UniProtKB/Swiss-Prot:P46788" FT /protein_id="CAB82086.1" FT /translation="MAYGQKILKGDAYKRAAIKRRHIRIRKNLSGTAERPRLVVTRSNR FT HIVAQVIDDIKGHTLASASTLDTSIRGGEADKSAQAKQVGALVAERAKAAGVEAVVFDR FT GGNQYAGRIAALADAAREAGLKF" FT misc_feature 57809..58153 FT /note="Pfam match to entry PF00861 Ribosomal_L18p, FT Ribosomal L18p/L5e family, score 204.90, E-value 1.3e-57" FT misc_feature 57848..57898 FT /note="PS00358 Ribosomal protein L5 signature" FT RBS 58187..58191 FT CDS 58200..58805 FT /transl_table=11 FT /gene="SCO4719" FT /gene_synonym="rpsE" FT /gene_synonym="SCD31.44" FT /product="30S ribosomal protein S5" FT /note="SCD31.44, rpsE, 30S ribosomal protein S5, len: 201 FT aa; identical to previously sequenced SW:RS5_STRCO FT (EMBL:X83011) Streptomyces coelicolor 30S ribosomal protein FT S5 RpsE, 201 aa. Contains Pfam match to entry PF00333 FT Ribosomal_S5, Ribosomal protein S5 and match to Prosite FT entry PS00585 Ribosomal protein S5 signature" FT /db_xref="GOA:P46790" FT /db_xref="HSSP:1PKP" FT /db_xref="InterPro:IPR018192" FT /db_xref="UniProtKB/Swiss-Prot:P46790" FT /protein_id="CAB82087.1" FT /translation="MAGPQRRGSGAGGGERRDRKGRDGGAGAAEKTAYVERVVAINRVA FT KVVKGGRRFSFTALVVVGDGDGTVGVGYGKAKEVPAAIAKGVEEAKKHFFKVPRIQGTI FT PHPIQGEKAAGVVLLKPASPGTGVIAGGPVRAVLECAGIHDVLSKSLGSDNQINIVHAT FT VEALKGLQRPEEIAARRGLPLEDVAPAALLRARAGAGA" FT misc_feature 58311..58697 FT /note="Pfam match to entry PF00333 Ribosomal_S5, Ribosomal FT protein S5, score 262.80, E-value 4.5e-75" FT misc_feature 58350..58448 FT /note="PS00585 Ribosomal protein S5 signature" FT CDS 58808..58990 FT /transl_table=11 FT /gene="SCO4720" FT /gene_synonym="rpmD" FT /gene_synonym="SCD31.45" FT /product="50S ribosomal protein L30" FT /note="SCD31.45, rpmD, 50S ribosomal protein L30, len: 60 FT aa; identical to previously sequenced SW:RL30_STRCO FT (EMBL:X83011) Streptomyces coelicolor 50S ribosomal protein FT L30 RpmD, 60 aa. Contains Pfam match to entry PF00327 FT Ribosomal_L30, Ribosomal protein L30p/L7e and match to FT Prosite entry PS00634 Ribosomal protein L30 signature" FT /db_xref="GOA:P46789" FT /db_xref="HSSP:1BXY" FT /db_xref="InterPro:IPR000517" FT /db_xref="UniProtKB/Swiss-Prot:P46789" FT /protein_id="CAB82088.1" FT /translation="MAQLKITQVKSYIGSKQNHRDTLRSLGLKGINTQVVKEDRPEFRG FT MVHTVRHLVTVEEVD" FT misc_feature 58811..58969 FT /note="Pfam match to entry PF00327 Ribosomal_L30, Ribosomal FT protein L30p/L7e, score 92.60, E-value 1.3e-26" FT misc_feature 58871..58969 FT /note="PS00634 Ribosomal protein L30 signature" FT RBS 58977..58982 FT CDS 58993..59448 FT /transl_table=11 FT /gene="SCO4721" FT /gene_synonym="rplO" FT /gene_synonym="SCD31.46" FT /product="50S ribosomal protein L15" FT /note="SCD31.46, rplO, 50S ribosomal protein L15, len: 151 FT aa; identical to previously sequenced SW:RL15_STRCO FT (EMBL:X83011) Streptomyces coelicolor 50S ribosomal protein FT L15 RplO, 151 aa. Contains Pfam matches to entries PF01305 FT Ribosomal_L15, Ribosomal protein L15 amino terminal region FT and fam match to entry PF00256 L15, Ribosomal protein L15 FT and matches to Prosite entries PS00017 ATP/GTP-binding site FT motif A (P-loop) and PS00475 Ribosomal protein L15 FT signature" FT /db_xref="GOA:P46787" FT /db_xref="InterPro:IPR005749" FT /db_xref="UniProtKB/Swiss-Prot:P46787" FT /protein_id="CAB82089.1" FT /translation="MAENNPLKIHNLRPAPGAKTAKTRVGRGEASKGKTAGRGTKGTKA FT RYQVPERFEGGQMPLHMRLPKLKGFKNPFKTEFQVVNLDKLAALYPEGGEVTVEGLVAK FT GAVRKNSLVKVLGQGEISVALQVTVDAVSGSAKEKITAAGGTVTELV" FT misc_feature 59011..59313 FT /note="Pfam match to entry PF01305 Ribosomal_L15, Ribosomal FT protein L15 amino terminal region, score 172.10, E-value FT 9e-48" FT misc_feature 59074..59097 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 59332..59424 FT /note="PS00475 Ribosomal protein L15 signature" FT misc_feature 59332..59427 FT /note="Pfam match to entry PF00256 L15, Ribosomal protein FT L15, score 49.00, E-value 1.8e-16" FT RBS 59695..59700 FT CDS 59705..61018 FT /transl_table=11 FT /gene="SCO4722" FT /gene_synonym="secY" FT /gene_synonym="SCD31.47" FT /product="preprotein translocase SecY subunit" FT /note="SCD31.47, secY, preprotein translocase SecY subunit, FT len: 437 aa; identical to previously sequenced FT SW:SECY_STRCO (EMBL:X83011) Streptomyces coelicolor FT preprotein translocase SecY subunit, 437 aa. Contains Pfam FT match to entry PF00344 secY, eubacterial secY protein and FT matches to Prosite entries PS00755 Protein secY signature 1 FT and PS00756 Protein secY signature 2. Contains also FT possible hydrophobic membrane spanning regions" FT /db_xref="GOA:P46785" FT /db_xref="InterPro:IPR002208" FT /db_xref="UniProtKB/Swiss-Prot:P46785" FT /protein_id="CAB82090.1" FT /translation="MLTAFARAFKTPDLRKKLLFTLGIIVVYRLGTHIPIPGVDYKNVQ FT ECVDQASGNQGLFGLVNMFSGGALLQITVFALGIMPYITASIILQLLTVVIPRLEALKK FT EGQAGTAKITQYTRYLTVALAILQGTGLVATARSGALFSGCTVAGQIVPDQAIFTTVVM FT VICMTAGTCVVMWLGELITDRGIGNGMSILMFISIAATFPSALWAIKKQGELADGWIEF FT GTVILVGLVMVGLVVFVEQAQRRIPVQYAKRMIGRRSYGGTSTYIPLKVNQAGVIPVIF FT ASSLLYIPALIVQFSNSTAGWATWITKNLADTAATPHIILYFFLIVFFAFFYVAISFNP FT EEVADNMKKYGGFIPGIRAGRPTAEYLSYVLNRITWPGSLYLGLIALVPTMALAGFGAN FT QNFPFGGTSILIIVGVGLETVKQIESQLQQRNYEGFLR" FT misc_feature 59921..59980 FT /note="PS00755 Protein secY signature 1" FT misc_feature 59921..60970 FT /note="Pfam match to entry PF00344 secY, eubacterial secY FT protein, score 698.20, E-value 4e-206" FT misc_feature 60230..60286 FT /note="PS00756 Protein secY signature 2" FT CDS 61018..61671 FT /transl_table=11 FT /gene="SCO4723" FT /gene_synonym="adk" FT /gene_synonym="SCD31.48" FT /product="adenylate kinase" FT /note="SCD31.48, adk, adenylate kinase (fragment), len: FT >157 aa; identical to previously sequenced SW:KAD_STRCO FT (EMBL:X83011) Streptomyces coelicolor adenylate kinase (EC FT 2.7.4.3) (ATP-AMP transphosphorylase) Adk, 217 aa. Contains FT Pfam match to entry PF00406 adenylatekinase, Adenylate FT kinase and matches to Prosite entry PS00113 Adenylate FT kinase signature" FT /note="SC6G4.01, adk, adenylate kinase, partial CDS, len: > FT 94 aa; almost identical to KAD_STRCO adenylate kinase (EC 2 FT .7.4.3) (205 aa) and highly similar to many e.g. KAD_BORPE FT adenylate kinase (EC 2.7.4.3)(218 aa), fasta scores; opt: 2 FT 53 z-score: 429.1 E(): 1.2e-16, 50.6% identity in 85 aa ove FT rlap. Contains Pfam match to entry PF00406 adenylatekinase, FT Adenylate kinases, score 136.80, E-value 3.2e-37" FT /db_xref="GOA:P43414" FT /db_xref="HSSP:1AKE" FT /db_xref="InterPro:IPR007862" FT /db_xref="UniProtKB/Swiss-Prot:P43414" FT /protein_id="CAD55214.1" FT /translation="MRIVLVGPPGAGKGTQATRLAETLHIPHISTGDLFRANISQQTEL FT GKLAKSYMNAGNLVPDEVTIAMAKDRMEQPDAEGGFLLDGFPRNVSQAEALDELLETEG FT MKLDAVLDLEAPEDEVVKRIAGRRVCRNEPKHVFHVTYTPPKKEGVCDVCGGELYQRDD FT DSEETVRKRLEVYHTQTEPIIDYYKSQGLVATIAATGPVDEVTRRALEALKRDQ" FT misc_feature 61030..61482 FT /note="Pfam match to entry PF00406 adenylatekinase, FT Adenylate kinase, score 331.10, E-value 1.2e-95" FT misc_feature 61258..61293 FT /note="PS00113 Adenylate kinase signature" FT misc_feature 61386..62995 FT /note="98.4% match to SCSECYDNA X83011 S.coelicolor secY lo FT cus DNA from 4547 to 6154" FT misc_feature 61387..61593 FT /note="Pfam match to entry PF00406 adenylatekinase, Adenyla FT te kinases, score 136.80, E-value 3.2e-37" FT RBS 61808..61811 FT /note="possible RBS upstream of map" FT CDS 61823..62659 FT /transl_table=11 FT /gene="SCO4724" FT /gene_synonym="map" FT /product="methionine aminopeptidase" FT /note="SC6G4.02, map, methionine aminopeptidase, len: 278 FT aa; identical to TR:O54208 (EMBL:X83011) methionine FT aminopeptidase (278 aa) and highly similar to many FT e.g.AMPM_BACSU methionine aminopeptidase (EC 3.4.11.18) FT (248 aa), fasta scores; opt: 546 z-score: 922.2 E(): 0, FT 44.5% identity in 256 aa overlap. Also similar to S. FT coelicolor map2 (E(): 3.2e-3 3, 46.8% identity in 267 aa FT overlap). Contains PS00680 Meth ionine aminopeptidase FT subfamily 1 signature and Pfam match to entry PF00557 FT pep_M24, metallopeptidase family M24, scor e 194.80, FT E-value 1.4e-54" FT /db_xref="GOA:O54208" FT /db_xref="HSSP:1O0X" FT /db_xref="InterPro:IPR002467" FT /db_xref="UniProtKB/TrEMBL:O54208" FT /protein_id="CAA20380.1" FT /translation="MVQIKNPEQIAKMREAGLVVAAIHAATREAAVPGATTKDLDQVAR FT KVLAEHDAKPNFLGYGGFPATICTSVNEVVVHGIPSDDVVLKDGDVISIDCGAIIDGWH FT GDAAYTAFVGSGHSPELVELSRVTEESMWAGIAAMKQGNRLVDVSRAIETYIRRQPKPG FT GGKYGIIEDYGGHGIGTEMHMDPHLLNYVDRRRGKGPKLVPGFCLAIEPMVSLGTPRTE FT VLPDEWTVITTDGTWSSHWEHSVALTEQGPLVLTSPDGGKAKLAELGITAAPDPLA" FT misc_feature 61829..62581 FT /note="Pfam match to entry PF00557 pep_M24, metallopeptidas FT e family M24, score 194.80, E-value 1.4e-54" FT misc_feature 62339..62395 FT /note="PS00680 Methionine aminopeptidase subfamily 1 signat FT ure" FT RBS 62790..62793 FT /note="possible RBS upstream of infA" FT CDS 62801..63022 FT /transl_table=11 FT /gene="SCO4725" FT /gene_synonym="SC6G4.03" FT /gene_synonym="infA" FT /product="translational initiation factor IF1" FT /note="SC6G4.03, infA, translational initiation factor IF1, FT len: 73 aa; identical to TR:O54209 (EMBL:X83011) FT translational initiation factor IF1 (fragment) (65 aa) and FT highly similar to many e.g. IF1_BACSU translation FT initiation factor IF-1 (71 aa), fasta scores; opt: 384 FT z-score: 792.5 E(): 0 , 78.6% identity in 70 aa overlap. FT Contains Pfam match to e ntry PF00575 S1, S1 RNA binding FT motif, score 54.10, E-value 3.1e-12" FT /db_xref="GOA:P60515" FT /db_xref="HSSP:1AH9" FT /db_xref="InterPro:IPR006196" FT /db_xref="UniProtKB/Swiss-Prot:P60515" FT /protein_id="CAA20381.1" FT /translation="MAKKQGAIEIEGTVVESLPNAMFKVELQNGHQVLAHISGKMRMHY FT IRILPDDRVVVELSPYDLTRGRIVYRYK" FT misc_feature 62807..63019 FT /note="Pfam match to entry PF00575 S1, S1 RNA binding motif FT , score 54.10, E-value 3.1e-12" FT RBS 63075..63078 FT /note="possible RBS upstream of rpmJ" FT misc_feature 63091..63201 FT /note="Pfam match to entry PF00444 L36, Ribosomal protein L FT 36, score 70.40, E-value 3.1e-22" FT CDS 63091..63204 FT /transl_table=11 FT /gene="SCO4726" FT /gene_synonym="SC6G4.04" FT /gene_synonym="rpmJ" FT /product="50S ribosomal protein L36" FT /note="SC6G4.04, rpmJ, 50S ribosomal protein L36, len: 37 FT aa; highly similar to many e.g. RL36_BACST 50S ribosomal FT protein L36 (37 aa), fasta scores; opt: 225 z-score: 380.1 FT E() : 6.6e-14, 78.4% identity in 37 aa overlap. Contains FT PS0082 8 Ribosomal protein L36 signature and Pfam match to FT entry PF00444 L36, Ribosomal protein L36, score 70.40, FT E-value 3.1 e-22" FT /db_xref="GOA:P66301" FT /db_xref="HSSP:1DFE" FT /db_xref="InterPro:IPR000473" FT /db_xref="UniProtKB/Swiss-Prot:P66301" FT /protein_id="CAA20382.1" FT /translation="MKVKPSVKKICDKCRVIRRHGRVMVICDNPRHKQRQG" FT misc_feature 63121..63198 FT /note="PS00828 Ribosomal protein L36 signature" FT RBS 63382..63385 FT /note="possible RBS upstream of rpsM" FT CDS 63393..63773 FT /transl_table=11 FT /gene="SCO4727" FT /gene_synonym="SC6G4.05" FT /gene_synonym="rpsM" FT /product="30S ribosomal protein S13" FT /note="SC6G4.05, rpsM, 30S ribosomal protein S13, len: 126 FT aa; highly similar to many e.g. RS13_BACSU 30S ribosomal FT protein S13 (BS14) (120 aa), fasta scores; opt: 537 FT z-score: 986.9 E(): 0, 65.3% identity in 121 aa overlap. FT Contains PS 00646 Ribosomal protein S13 signature and Pfam FT match to entry PF00416 S13, Ribosomal protein S13, score FT 186.70, E-value 3.8e-52" FT /db_xref="GOA:O86773" FT /db_xref="InterPro:IPR018269" FT /db_xref="UniProtKB/Swiss-Prot:O86773" FT /protein_id="CAA20383.1" FT /translation="MARVSGVDIPREKRVEIALTYVFGIGRTLSQQTLAATGVDPNTRV FT RDLSEEQLVAIREYVDNNIKTEGDLRREVQADIRRKVEIGTYQGLRHRRGLPVRGQRTS FT TNARTRKGPRRAIAGKKKPGKK" FT misc_feature 63399..63719 FT /note="Pfam match to entry PF00416 S13, Ribosomal protein S FT 13, score 186.70, E-value 3.8e-52" FT misc_feature 63654..63695 FT /note="PS00646 Ribosomal protein S13 signature" FT RBS 63830..63834 FT /note="possible RBS upstream of rpsK" FT CDS 63841..64245 FT /transl_table=11 FT /gene="SCO4728" FT /gene_synonym="SC6G4.06" FT /gene_synonym="rpsK" FT /product="30S ribosomal protein S11" FT /note="SC6G4.06, rpsK, 30S ribosomal protein S11, len: 134 FT aa; highly similar to many e.g. RS11_BACSU 30S ribosomal FT protein S11 (131 aa), fasta scores; opt: 601 z-score: FT 1026.7 E(): 0, 69.8% identity in 129 aa overlap. Contains FT PS00054 Ribosomal protein S11 signature and Pfam match to FT entry PF00411 S11, Ribosomal protein S11, score 247.00, FT E-value 5.7e -76" FT /db_xref="GOA:P72403" FT /db_xref="InterPro:IPR018102" FT /db_xref="UniProtKB/Swiss-Prot:P72403" FT /protein_id="CAA20384.1" FT /translation="MPPKGRQGAAKKVRRKEKKNVAHGHAHIKSTFNNTIVSITDPTGN FT VISWASAGHVGFKGSRKSTPFAAQMAAESAARRAQEHGMRKVDVFVKGPGSGRETAIRS FT LQATGLEVGSIQDVTPTPHNGCRPPKRRRV" FT misc_feature 63910..64239 FT /note="Pfam match to entry PF00411 S11, Ribosomal protein S FT 11, score 247.00, E-value 5.7e-76" FT misc_feature 64144..64212 FT /note="PS00054 Ribosomal protein S11 signature" FT misc_feature 64153..65558 FT /note="98.2% match to SCRPOA X92107 S.coelicolor rpoA and r FT psK genes from 1 to 1401" FT RBS 64365..64369 FT /note="possible RBS upstream of rpoA" FT CDS 64377..65399 FT /transl_table=11 FT /gene="SCO4729" FT /gene_synonym="SC6G4.07" FT /gene_synonym="rpoA" FT /product="DNA-directed RNA polymerase alpha chain" FT /note="SC6G4.07, rpoA, DNA-directed RNA polymerase alpha FT chain, len: 340 aa; almost identical to RPOA_STRCO FT DNA-directed RNA polymerase alpha chain (EC 2.7.7.6) (339 FT aa)99.1% id entity in 340 aa overlap, and highly similar to FT many e.g. R POA_BACSU (314 aa), fasta scores; opt: 917 FT z-score: 1326.7 E(): 0, 48.9% identity in 311 aa overlap. FT Contains PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:P60312" FT /db_xref="HSSP:1HQM" FT /db_xref="InterPro:IPR011773" FT /db_xref="UniProtKB/Swiss-Prot:P60312" FT /protein_id="CAA20385.1" FT /translation="MLIAQRPSLTEEVVDEFRSRFVIEPLEPGFGYTLGNSLRRTLLSS FT IPGAAVTSIRIDGVLHEFTTVPGVKEDVTDLILNIKQLVVSSEHDEPVVMYLRKQGPGL FT VTAADIAPPAGVEVHNPDLVLATLNGKGKLEMELTVERGRGYVSAVQNKQVGQEIGRIP FT VDSIYSPVLKVTYKVEATRVEQRTDFDKLIVDVETKQAMRPRDAMASAGKTLVELFGLA FT RELNIDAEGIDMGPSPTDAALAADLALPIEELELTVRSYNCLKREGIHSVGELVARSEA FT DLLDIRNFGAKSIDEVKAKLAGMGLALKDSPPGFDPTAAADAFGADDDADAGFVETEQY FT " FT misc_feature 64995..65018 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 65582..65586 FT /note="possible RBS upstream of rplQ" FT CDS 65594..66100 FT /transl_table=11 FT /gene="SCO4730" FT /gene_synonym="SC6G4.08" FT /gene_synonym="rplQ" FT /product="50S ribosomal protein L17" FT /note="SC6G4.08, rplQ, 50S ribosomal protein L17, len: 168 FT aa; highly similar to many e.g. RL17_BACST 50S ribosomal FT protein L17 (119 aa), fasta scores; opt: 339 z-score: 597.2 FT E (): 5.3e-26, 47.4% identity in 116 aa overlap. Contains FT approx 50 aa C-terminal extension, not present in other FT RplQ" FT /db_xref="GOA:O86775" FT /db_xref="HSSP:1GD8" FT /db_xref="InterPro:IPR000456" FT /db_xref="UniProtKB/Swiss-Prot:O86775" FT /protein_id="CAA20386.1" FT /translation="MPKPSKGARLGGSAAHEKLLLANLAKSLFEHGRITTTEAKARKLR FT PYAERLVTKAKKGDLHNRRQVLQVITDKSIVHTLFTEIGPRYENRPGGYTRITKIGNRR FT GDNAPMAVIELVEALTVAQQATGEAEAATKRAAKDAEGSAEVSEAKVDTTKADDEAAAE FT ESKDA" FT RBS 66228..66231 FT /note="possible RBS upstream of truA" FT CDS 66240..67094 FT /transl_table=11 FT /gene="SCO4731" FT /gene_synonym="SC6G4.09" FT /gene_synonym="truA" FT /product="putative pseudouridylate synthase" FT /note="SC6G4.09, truA, probable pseudouridylate synthase, FT len: 284 aa; similar to many e.g. TRUA_ECOLI FT pseudouridylate synthase I (EC 4.2.1.70) (270 aa), fasta FT scores; opt: 466 z-score: 630.6 E(): 7.4e-28, 35.1% FT identity in 265 aa over lap" FT /db_xref="GOA:O86776" FT /db_xref="HSSP:1DJ0" FT /db_xref="InterPro:IPR020094" FT /db_xref="UniProtKB/Swiss-Prot:O86776" FT /protein_id="CAA20387.1" FT /translation="MSDEVEAGFVRVRLDLSYDGSEFSGWAKQAGGRRTVQGEIEDALR FT TVTRSRETYELTVAGRTDAGVHARGQVAHVDLPREVWAEHHVKLLKRLAGRLPRDVRVW FT ALREAPSGFNARFSAVWRRYAYRVTDNPGGVDPLLRGHVLWHDWPLDVDAMNAAARGLL FT GEHDFAAYCKKREGATTIRTLQELSLVRGEDGIVTATVRADAFCHNMVRSLIGALLFVG FT DGHRGPEWPAKVLAAGVRDSAVHVVRPHGLTLEEVGYPADELLAARNKEARNKRSLPGA FT GCC" FT CDS complement(67114..68013) FT /transl_table=11 FT /gene="SCO4732" FT /gene_synonym="SC6G4.10c" FT /product="putative membrane protein" FT /note="SC6G4.10c, putative membrane protein, len: 299 aa; FT contains possible transmembrane domain near N-terminus" FT /db_xref="UniProtKB/TrEMBL:O86777" FT /protein_id="CAA20388.1" FT /translation="MSFGQGGPQSQWDPWTPQSQQPPSQQPWNSGNSDDTPDWAALAEA FT SEARAKRRRLFFIGGGALATVAIAGAVAVAVVSANGSDQASDGGSSQLPTTAEIPSATA FT TEPSFAPTSAPPPLDPKDFVSSVKKDKAPLSPDLLFPGTQLTMGETVYKKGPTADTRTC FT GSAAQGTLPKVLDANRCTRLIRVTYTQGDTAVTVGVAVFDTEAQAAKAKKDADKKSIVR FT SLSGGGVKSFCTGAVCRSTTNSYGRYAYFTVAGFTGAKDVTEKSTGVFRAGDDLAEFAF FT RQIRRRGEAQASAAAEAG" FT CDS 68058..69293 FT /transl_table=11 FT /gene="SCO4733" FT /gene_synonym="SC6G4.11" FT /product="putative integral membrane protein" FT /note="SC6G4.11, probable integral membrane protein, len: 4 FT 11 aa; some similarity to hypothetical proteins from M. FT tuberculosis and M. leprae e.g. TR:P71970 (EMBL:) FT MTCY441.42 ( Rv2673) (433 aa), fasta scores; opt: 383 FT z-score: 365.0 E() : 4.6e-13, 29.6% identity in 422 aa FT overlap" FT /db_xref="InterPro:IPR018584" FT /db_xref="UniProtKB/TrEMBL:Q53873" FT /protein_id="CAA20389.1" FT /translation="MGPAGPSVPCMRTGKSDISGWLVRPAGRHPWAVLATVLAASAAHA FT ARTTSDGGMDNAIVVRAARTWLAGGSPYDDPHFLYLPSAVLAAVPQALLPGAVLRVLVP FT CAVTVLLALAWACALRLHRVPLGSRLAVLGLTGLALGFAPFGHLVRLGNWTVTATVALP FT LALLLASRGRWTGAGVVIGAAVALKPLLAPVVLLFLFAGRWRALAAAVLVPALASAAAA FT LAMPDPAGFFTRTLPFLLHGEDGFVRLYEASPAAVLPRLGVPPALAQGLAVAAASAGVL FT CAYRRWRRADPGPLRLAETGAGLMLSAFLVSRPSYDHYLLVALPLLLAGLPYAGSVARG FT AWFWIALVPQVPGLTWPWLEGERRRAFRDAFTLCVLAVTVARQARTGPAGADDRVPQGR FT SPEPERAPAAPF" FT misc_feature 69117..70855 FT /note="100% match to SC43429 U43429 Streptomyces coelicolor FT ribosomal protein L13 (rplM) and S9 (rpsI) genes from 1 to FT 1739" FT CDS 69501..69944 FT /transl_table=11 FT /gene="SCO4734" FT /gene_synonym="rplM" FT /product="50S ribosomal protein L13" FT /note="SC6G4.12, rplM, 50S ribosomal protein L13, len: 147 FT aa; identical to RL13_STRCO 50S ribosomal protein L13 (147 FT aa) and highly similar to many e.g. RL13_ECOLI (142 aa), fa FT sta scores; opt: 557 z-score: 970.2 E(): 0, 53.5% identity FT in 142 aa overlap. Contains PS00783 Ribosomal protein L13 s FT ignature and Pfam match to entry PF00572 L13, Ribosomal pro FT tein L13, score 252.90, E-value 4.4e-72" FT /db_xref="GOA:Q53874" FT /db_xref="InterPro:IPR005823" FT /db_xref="UniProtKB/Swiss-Prot:Q53874" FT /protein_id="CAA20390.1" FT /translation="MRTYSPKPGDVTRQWHVIDAQDVVLGRLATTAASILRGKHKPIYA FT PHVDTGDFVIIINADKVHLSGNKRTQKMAYRHSGYPGGLRSVRYDELLDKNPEKAVEKA FT IKGMLPKNSLGRQMLSKLKVYKGDQHPHGAQQPQPFEITQVAQ" FT misc_feature 69534..69926 FT /note="Pfam match to entry PF00572 L13, Ribosomal protein L FT 13, score 252.90, E-value 4.4e-72" FT misc_feature 69813..69881 FT /note="PS00783 Ribosomal protein L13 signature" FT RBS 69978..69982 FT /note="possible RBS upstream of rpsI" FT CDS 69987..70499 FT /transl_table=11 FT /gene="SCO4735" FT /gene_synonym="rpsI" FT /product="30S ribosomal protein S9" FT /note="SC6G4.13, rpsI, 30S ribosomal protein S9, len: 170 a FT a; identical to RS9_STRCO 30S ribosomal protein S9 (170 aa) FT and highly similar to many e.g.RS9_ECOLI (129 aa), fasta s FT cores; opt: 408 z-score: 663.5 E(): 1.1e-29, 49.2% identity FT in 124 aa overlap. Contains PS00360 Ribosomal protein S9 s FT ignature and Pfam match to entry PF00380 S9, Ribosomal prot FT ein S9, score 162.60, E-value 1e-49" FT /db_xref="GOA:Q53875" FT /db_xref="InterPro:IPR000754" FT /db_xref="UniProtKB/Swiss-Prot:Q53875" FT /protein_id="CAA20391.1" FT /translation="MAETTPEQPLEEIDIDSYTTESEVPVEGEYTSESMASAFGEPQPA FT AGLGRRKNAIARVRIVPGTGKWKVNGRTLEDYFPNKVHQQEVNEPFKVLELDNRYDVIA FT RISGGGVSGQAGALRLGVARALNEADVDNNRGALKKAGYLKRDDRAVERKKAGLKKARK FT APQYSKR" FT misc_feature 70131..70496 FT /note="Pfam match to entry PF00380 S9, Ribosomal protein S9 FT , score 162.60, E-value 1e-49" FT misc_feature 70308..70364 FT /note="PS00360 Ribosomal protein S9 signature" FT RBS 70714..70719 FT /note="possible RBS upstream of SC6G4.14" FT misc_feature 70724..72034 FT /note="Pfam match to entry PF00408 PGM_PMM, Phosphoglucomut FT ase and phosphomannomutase, score 356.30, E-value 3.4e-103" FT CDS 70724..72082 FT /transl_table=11 FT /gene="SCO4736" FT /gene_synonym="SC6G4.14" FT /product="putative phospho-sugar mutase" FT /note="SC6G4.14, probable phospho-sugar mutase, len: 452 aa FT ; similar to many phosphomannomutases and phoshoglucomutase FT s; also similar to to MRSA_ECOLI MRSA protein (445 aa), fas FT ta scores; opt: 1131 z-score: 827.7 E(): 0, 44.8% identity FT in 455 aa overlap, and to H. pylori UREC_HELPY putative ure FT ase operon ureC protein (445 aa), fasta scores; opt: 970 z- FT score: 1202.7 E(): 0, 39.6% identity in 434 aa overlap. Con FT tains Pfam match to entry PF00408 PGM_PMM, Phosphoglucomuta FT se and phosphomannomutase, score 356.30, E-value 3.4e-103" FT /db_xref="GOA:Q53876" FT /db_xref="InterPro:IPR005846" FT /db_xref="UniProtKB/Swiss-Prot:Q53876" FT /protein_id="CAA20392.1" FT /translation="MGRLFGTDGVRGVANADLTAELALGLSVAAAHVLAEAGTFAGHRA FT TAVVGRDPRASGEFLEAAVVAGLASAGVDVLRVGVLPTPAVAHLTGALGADLGVMLSAS FT HNAMPDNGIKFFARGGHKLADELEDRIESVYADHRTGAPWDRPTGSGVGRVRDYDEGLD FT QYVAHLVGVLPNRLDGLKIVLDEAHGAASRVSPEAFARAGAELVTIGAVPDGLNINDGC FT GSTHLDLLKAAVVEHGADLGIAHDGDADRCLAVDHTGAEVDGDQILAVLALAMREREAL FT RSDTVVATVMSNLGFKLAMEREGIRFVQTGVGDRYVLEEMKEHGYALGGEQSGHVIILD FT HATTGDGTLTGLMLAARVAQTGRTLRDLASVMERLPQVLVNVPDVDKSRVTSSAELATA FT VAEAERELGSTGRVLLRPSGTEPLVRVMVEAADIEQARSVAGRLADSVKSALG" FT CDS complement(72210..73157) FT /transl_table=11 FT /gene="SCO4737" FT /gene_synonym="SC6G4.15c" FT /product="putative integral membrane protein" FT /note="SC6G4.15c, probable integral membrane protein, len: FT 452 aa; simialar to hypothetical protein from Streptomyces FT albus TR:Q53581 (EMBL:U03114) partial CDS (208 aa), fasta FT scores; opt: 821 z-score: 1301.7 E(): 0, 67.0% identity in FT 203 aa overlap" FT /db_xref="InterPro:IPR005240" FT /db_xref="UniProtKB/TrEMBL:O86778" FT /protein_id="CAA20393.1" FT /translation="MLHLRLITPADRTDEVVRLIDRTVGTTHLVVLPGAAREPEGDVVM FT CDVAREAGDELINGLRGLGIDRCGAITAENIDLSLSERADRAERDAPGEPADAVLWEQL FT EEATHEESTLSITYVAFITLATMIAACGVVLDNAVLIVGAMAVGPEFGPLAGICTAIVQ FT RAPRLALRSATALLVGFAVAMAVTVGFSWIMTEFGQFSEGKLEGERPNTGFVYAPDAFS FT FVVAVLAGIAGTLSLTSAKSGALVGVAISVTTVPAAANAAVALSFGDTNQTVGSTEQLL FT LNLAGIVVAGTLTLLAQKALWATQRSRLTKPENS" FT CDS complement(73218..74207) FT /transl_table=11 FT /gene="SCO4738" FT /gene_synonym="coaA" FT /product="putative pantothenate kinase" FT /note="SC6G4.16c, coaA, probable pantothenate kinase, len: FT 329 aa; similar to e.g. COAA_ECOLI pantothenate kinase (EC FT 2.7.1.33) (316 aa), fasta scores; opt: 1100 z-score: 1601.0 FT E(): 0, 51.4% identity in 315 aa overlap. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:O86779" FT /db_xref="HSSP:1ESM" FT /db_xref="InterPro:IPR004566" FT /db_xref="UniProtKB/Swiss-Prot:O86779" FT /protein_id="CAA20394.1" FT /translation="MISPVPSIPRSAHRQRPEATPYVDLTRPEWSALRDKTPLPLTAEE FT VEKLRGLGDVIDLDEVRDIYLPLSRLLNLYVGATDGLRGALNTFLGEQGSQSGTPFVIG FT VAGSVAVGKSTVARLLQALLSRWPEHPRVELVTTDGFLLPTRELEARGLMSRKGFPESY FT DRRALTRFVADIKAGKAEVTAPVYSHLIYDIVPDQRLVVRRPDILIVEGLNVLQPALPG FT KDGRTRVGLADYFDFSVYVDARTEDIERWYLNRFRKLRATAFQNPSSYFRKYTQVSEEE FT ALDYARTTWRTINKPNLVENVAPTRGRATLVLRKGPDHKVQRLSLRKL" FT misc_feature complement(73866..73889) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 74467..75273 FT /transl_table=11 FT /gene="SCO4739" FT /gene_synonym="SC6G4.17" FT /product="putative lipoprotein" FT /note="SC6G4.17, probable lipoprotein, len: 268 aa; contain FT s N-terminal signal sequence and appropriately positioned P FT S00013 Prokaryotic membrane lipoprotein lipid attachment si FT te" FT /db_xref="UniProtKB/TrEMBL:O86780" FT /protein_id="CAA20395.1" FT /translation="MSSTAVRRTALVASAAALTLLATACGGSSDDDGAAGEETAKTEQS FT ASAGGAEESAPAGKALTAAELEKVALAQADVKNGKVATELSADDQVAKDQISADDKACL FT PLVYVQGAVAQGEPAADVQRSWQGQTEAPSESKGPDGQDMTDIDVNEILLNVASYEDGG FT AEQAVAGLKAAVEKCAGGFVATVGSDKMQVTEVSGAQAPKGGDEGLTVNIGVATGGDSS FT GLMKLVVVRKGATLATFGAVNLSSMMTGAEFEVPAEVVDAQVAKLG" FT misc_feature 74509..74541 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid attac FT hment site" FT CDS 75384..77231 FT /transl_table=11 FT /gene="SCO4740" FT /gene_synonym="SC6G4.18" FT /gene_synonym="glmS1" FT /product="glucosamine--fructose-6-phosphate FT aminotransferase" FT /note="SC6G4.18, glmS1, probable FT glucosamine--fructose-6-phosphate aminotransferase, len: FT 615 aa; similar to many e.g. GLMS_ECOLI FT glucosamine--fructose-6-phosphate aminotransferase FT (isomerizing) (EC 2.6.1.16) (608 aa), fasta scores; opt : FT 1658 z-score: 1783.2 E(): 0, 44.3% identity in 621 aa ove FT rlap. Contains Pfam match to entry PF00310 GATase_2, FT Glutamine amidotransferases class-II, score 226.20, E-value FT 1.8e-76" FT /db_xref="GOA:O86781" FT /db_xref="HSSP:1GDO" FT /db_xref="InterPro:IPR001347" FT /db_xref="UniProtKB/Swiss-Prot:O86781" FT /protein_id="CAA20396.1" FT /translation="MCGIVGYVGPQSALDVVMAGLKRLEYRGYDSAGVAVLADGGLATA FT KRAGKLVNLDKELSEHPLPAAATGIGHTRWATHGGPTDANAHPHLDNAGRVAVVHNGII FT ENFAPLRAELAERGHELPSETDTEVVAHLLAEEYSACADLAEAMRLVCGRLEGAFTLVA FT VHADAPDVVVGARRNSPLVVGVGEGEYFLASDVAAFIAHTRDAVELGQDQVVELRRDGV FT RVTGFDGSPADVRSYHVDWDASAAEKCGYASFMLKEIAEQPKAVADTLLGRIDGSGTLS FT LDEVRIPPGVLREVDKVVVVACGTAFHAGLIAKYAIEHWTRIPCEVELASEFRYRDPIL FT DQQTLVVAISQSGETMDTLMALRHAREQGARVLAICNTNGSTIPRESDAVLYTHAGPEV FT AVASTKAFLTQLVACYLVALYLGQVRGTKYGDEIGDVVRDLSGISGAVERVLGTMDPVR FT QLARSLAHKNTVLFLGRHVGHPVALEGALKLKELAYMHAEGFAAGELKHGPIALIEEDL FT PVVVVVPSPRGRSVLHDKIVSNIQEIRARGARTIVIAEEGDEAVVPYADHLVRIPATPT FT LLQPLVATVPLQVFACELATARGNEVDQPRNLAKSVTVE" FT misc_feature 75387..75935 FT /note="Pfam match to entry PF00310 GATase_2, Glutamine amid FT otransferases class-II, score 226.20, E-value 1.8e-76" FT CDS complement(77263..77835) FT /transl_table=11 FT /gene="SCO4741" FT /gene_synonym="SC6G4.19c" FT /product="hypothetical protein" FT /note="SC6G4.19c, unknown, len: 190 aa; contains Pro-Ser- r FT ich domain at N-terminus" FT /db_xref="InterPro:IPR007374" FT /db_xref="UniProtKB/TrEMBL:O86782" FT /protein_id="CAA20397.1" FT /translation="MALEPDPPPPSPHPPSPPPPSPHPSSPPSSSSPSSSPSPPVPAPP FT VPGLGSLPRAEFGFPGPLRDRLVAAVLDGSKTSTTGLVADYEHEGEPLPEAGRREVVVD FT SRERPVAVIEVTEVRVVPLAEVDLAHAVDEGEGDTSVAGWRAGHERFWHGAEMRAALGD FT PGFTVDDATPVVLERFRIVTLLPAPGG" FT repeat_region complement(77695..77817) FT /note="corresponds to Pro-Ser rich region in SC6G4.19c" FT CDS complement(77881..79338) FT /transl_table=11 FT /gene="SCO4742" FT /gene_synonym="SC6G4.20c" FT /product="conserved hypothetical protein" FT /note="SC6G4.20c, unknown, len: 485 aa; similar to FT hypothetical proteins from many organisms e.g. Y115_MYCTU FT MTCY77.05 C (Rv3433c) (473 aa), fasta scores; opt: 563 FT z-score: 730.1 E(): 0, 48.5% identity in 489 aa overlap" FT /db_xref="HSSP:1KYH" FT /db_xref="InterPro:IPR004443" FT /db_xref="UniProtKB/TrEMBL:O86783" FT /protein_id="CAA20398.1" FT /translation="MRTAYSVETVRNAERELMARLPEGALMQRAAAGLAAACAQVLARV FT AGRVYGSRVVLLVGSGDNGGDALYAGARLARRGAGVTAVLLAPDRAHGGGLTALRRAGG FT RVAEGGPAGSAEELIARADLVLDGIVGIGGSGGLRKEAGPLADAAARSRAAVVAVDLPS FT GVDADTGRVRGDVVRADLTVTFGTHKPGLLIDPAREYAGSVRLVDIGLPLPGEAAELEA FT LQHPDVARLLPVPAGESDKYRRGVVGIAAGSARYPGAAVLAVAGALRGGAGAVRYVGPA FT GDAVIARFPETLVSDQGPKRAGRVQAWVVGPGAGDDAATVAQVLAAEVPVLIDADGLRL FT ADADAVRARTAPTLMTPHAGEAAALLGVGREEVEAARLDSVRELAARYGATVLLKGSTT FT LVARAKGGPVRVNATGTSWLATAGSGDVLSGLAGSLLAAGLSAVDAGSVGAYLHGLAGR FT FAAEGAPAGAHDVAAAIPRAWRDVRGD" FT CDS 79418..80023 FT /transl_table=11 FT /gene="SCO4743" FT /gene_synonym="SC6G4.21" FT /product="conserved hypothetical protein" FT /note="SC6G4.21, unknown, len: 201 aa; similar, in part, to FT a hypothetical protein from Streptomyces purpurascens TR:Q FT 54855 (EMBL:X61931) (90 aa), fasta scores; opt: 376 z-score FT : 584.3 E(): 2.8e-25, 58.5% identity in 94 aa overlap. Cont FT ains helix-turn-helix motif at aa 28-49 (Score 2176, +6.60 FT SD)" FT /db_xref="GOA:O86784" FT /db_xref="InterPro:IPR014710" FT /db_xref="UniProtKB/TrEMBL:O86784" FT /protein_id="CAA20399.1" FT /translation="MSGGDETAQVMTSLGARLRAIRQARGLTLAQLAAATGISVSTLSR FT LESGQREPGLRHLLPLARAHRLPLDELVGSRTGDPRVHPRPFTRHGQTWVPLTRNPNDG FT LHAYKQILPAPATPRTEWTPRPEQGSHEGHEWLYVLSGRLLLALGEHDLVLTAGETAEF FT DTRVPHGIANAGDQPVEWIALYGAQGERMHIRVRPTAG" FT CDS complement(80051..80422) FT /transl_table=11 FT /gene="SCO4744" FT /gene_synonym="SC6G4.22c" FT /gene_synonym="acpS" FT /product="putative holo-[acyl-carrier protein] synthase" FT /note="SC6G4.22c, acpS, probable holo-[acyl-carrier protein FT ] synthase, len: 123 aa; similar to many e.g. ACPS_ECOLI FT holo-[acyl-carrier protein] synthase (EC 2.7.8.7) (125 aa), FT fasta scores; opt: 237 z-score: 303.8 E(): 1.1e-09, 38.7% i FT dentity in 124 aa overlap" FT /db_xref="GOA:O86785" FT /db_xref="InterPro:IPR004568" FT /db_xref="PDB:2JBZ" FT /db_xref="UniProtKB/Swiss-Prot:O86785" FT /protein_id="CAA20400.1" FT /translation="MSIIGVGIDVAEVERFGAALERTPALAGRLFLESELLLPGGERRG FT VASLAARFAAKEALAKALGAPAGLLWTDAEVWVEAGGRPRLRVTGTVAARAAELGVASW FT HVSLSHDAGIASAVVIAEG" FT CDS 80558..81733 FT /transl_table=11 FT /gene="SCO4745" FT /gene_synonym="alr" FT /product="putative alanine racemase" FT /note="SC6G4.23, alr, probable alanine racemase, len: 391 a FT a; similar to many e.g. ALR_BACST alanine racemase (EC 5.1. FT 1.1) (388 aa), fasta scores; opt: 532 z-score: 774.2 E(): 0 FT , 38.6% identity in 376 aa overlap. Contains PS00395 FT Alanine racemase pyridoxal-phosphate attachment site" FT /db_xref="GOA:O86786" FT /db_xref="HSSP:1BD0" FT /db_xref="InterPro:IPR000821" FT /db_xref="UniProtKB/Swiss-Prot:O86786" FT /protein_id="CAA20401.1" FT /translation="MSETTARRDADAVLRARAEIDLAALRANVRALRERAPGAALMAVV FT KADAYGHGAIPCARAAVAAGATWLGTATPQEALALRAAEPGLPDDVRIMCWLWTPGGPW FT REAVEARLDVSVSAMWAMEEVTGAARAAGVPARVQLKADTGLGRGGCQPGADWERLVGA FT ALRAEEEGLLRVTGLWSHFACADEPGHPSIAAQLTRFREMTAYAEQRGLRPEVRHIANS FT PATLTLPDAHFDLVRPGIAMYGVSPSPEIGTPADFGLRPVMTLAASLALVKQVPGGHGV FT SYGHHYTTPGETTLGLVPLGYADGIPRHASSSGPVLVDGKWRTVAGRIAMDQFVVDLGG FT DRPEPGAEAVLFGPGDRGEPTAEDWAQAAGTIAYEIVTRIGSRVPRVYVNE" FT misc_feature 80687..80716 FT /note="PS00395 Alanine racemase pyridoxal-phosphate attachm FT ent site" FT RBS 81881..81884 FT /note="possible RBS upstream of SC6G4.24" FT CDS 81888..83150 FT /transl_table=11 FT /gene="SCO4746" FT /gene_synonym="SC6G4.24" FT /product="putative lipase" FT /note="SC6G4.24, possible lipase, len: 420 aa; some similar FT ity to e.g. TR:Q59695 (EMBL:L35343) Pseudomonas putida dihy FT drolipoamide acetyltransferase (370 aa), fasta scores; opt: FT 134 z-score: 204.4 E(): 0.00041, 27.0% identity in 352 aa FT overlap. Contains PS00120 Lipases, serine active site and P FT fam match to entry PF00561 abhydrolase, alpha/beta hydrolas FT e fold, score 79.50, E-value 7e-20. Contains possible FT hydrophobic membrane spanning region" FT /db_xref="InterPro:IPR000073" FT /db_xref="UniProtKB/TrEMBL:O86787" FT /protein_id="CAA20402.1" FT /translation="MHVSESNAEAVAAAVASATEAATEAAAGGWRRATGIAGVAIGVVA FT AGAAAGVAIERLTVGRGMRQKARLALDSTGPYGGLRGTPGKAYAEDGTELYYEVDDLDP FT EAGADPAPRRRRLFGRKAPAPVTVVFSHGYCLNQDSWHFQRAALRGVVRSVYWDQRSHG FT RSGRGVAQTRDDRPVSIEELGRDLKAVIDAAAPEGPIVLVGHSMGGMTVMALADAFPDL FT VRERVVGVALVGTSSGRLGEVNFGLPVAGVNAVRRVLPGVLRALGQRAELVERGRRATA FT DLFAGIIKRYSFASRDVDPAVARFAERMIESTPIDVVAEYYPAFNDHDKTEALAHFAGL FT PVLVLAGVRDLVTPSEHSEAIADLLPDAELVLVPDAGHLVMLEHPELVTDRLADLLARA FT GAVPAATTVDGYGSTSSTGPG" FT misc_feature 82362..83075 FT /note="Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold, score 79.50, E-value 7e-20" FT misc_feature 82485..82514 FT /note="PS00120 Lipases, serine active site" FT CDS 83221..83667 FT /transl_table=11 FT /gene="SCO4747" FT /gene_synonym="SC6G4.25" FT /product="putative ATP/GTP binding protein" FT /note="SC6G4.25, probable ATP/GTP binding protein, len: 148 FT aa; similar to hypothetical proteins from many organisms e FT .g. YJEE_ECOLI (153 aa), fasta scores; opt: 228 z-score: 29 FT 2.3 E(): 5.1e-09, 34.1% identity in 135 aa overlap and Y097 FT _MYCTU MTCY78.07 (168 aa), fasta scores; opt: 377 z-score: FT 532.7 E(): 2.1e-22, 50.8% identity in 120 aa overlap. Conta FT ins PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:O86788" FT /db_xref="HSSP:1HTW" FT /db_xref="InterPro:IPR003442" FT /db_xref="UniProtKB/Swiss-Prot:O86788" FT /protein_id="CAA20403.1" FT /translation="MRELGRRLAKLLRAGDLVMLSGELGAGKTTLTRGLGEGLGVRGAV FT TSPTFVIARVHPSLGDGPPLVHVDAYRLSGGLDEMEDLDLDVSLSDSVIVVEWGEGKVE FT ELTEDRLRLRIDRAVGDTADEVRHVTVTGLGERWATADVSVLAG" FT misc_feature 83284..83307 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 83803..83808 FT /note="RBS upstream of SC6G4.26" FT CDS 83814..84050 FT /transl_table=11 FT /gene="SCO4748" FT /gene_synonym="SC6G4.26" FT /product="hypothetical protein" FT /note="SC6G4.26, unknown, len: 78 aa; contains Gln-rich C-t FT erminus" FT /db_xref="UniProtKB/TrEMBL:O86789" FT /protein_id="CAA20404.1" FT /translation="MSSVSQAQPQGRPRHLPPAPAGVSMHDLLASCAAATAVSTPPRAP FT EPEARGPVRDQQGQQGRQSQQGQQDRQSHREAA" FT CDS complement(84086..84640) FT /transl_table=11 FT /gene="SCO4749" FT /gene_synonym="SC6G4.27c" FT /product="putative secreted protein" FT /note="SC6G4.27c, possible secreted protein, len: 184 aa; FT similar to TR:Q9KZZ6 (EMBL:AL353815) Streptomyces FT coelicolor putative secreted protein SCD6.08, 189 aa; fasta FT scores:opt: 495 Z-score: 540.3 E(): 1.8e-22; 48.066% FT identity in 181 aa overlap. Contains possible N-terminal FT signal sequence" FT /db_xref="UniProtKB/TrEMBL:O86790" FT /protein_id="CAA20405.1" FT /translation="MASRSAGIVTGLTTAALVTIGVLAHQASDSVPAGLDRTHATTSPA FT PGAAKAPRDRRHPDALPAMSGQGERVVYSVDDDRVWLVGPGNRVRRTFEVTPSTVDPAP FT GAYTVTSRSNRITGSDGIPVEHVVRFTGAQGVAIGFSAAVDGSTAAPDPDRPTGGIRES FT RADGDAMWKFATIGRQVVVVP" FT RBS complement(84649..84653) FT /note="possible RBS upstream of SC6G4.27c" FT CDS 84834..85487 FT /transl_table=11 FT /gene="SCO4750" FT /gene_synonym="SC6G4.28" FT /product="conserved hypothetical protein" FT /note="SC6G4.28, unknown, len: 217 aa; similar to FT hypothetical proteins from many organisms e.g. YEAZ_ECOLI FT (231 aa), fasta scores; opt: 257 z-score: 332.3 E(): 3e-11, FT 33.9% ide ntity in 221 aa overlapand Y098_MYCTU MTCY78.08 FT (211 aa), f asta scores; opt: 453 z-score: 467.2 E(): FT 9.3e-19, 48.1% i dentity in 212 aa overlap. Also some FT similarity to downstre am protein gcp (SC6G4.30; E(): FT 0.00023, 26.5% identity in 2 34 aa overlap)" FT /db_xref="GOA:O86791" FT /db_xref="InterPro:IPR000905" FT /db_xref="UniProtKB/TrEMBL:O86791" FT /protein_id="CAA20406.1" FT /translation="MLLLALDTATPAVTVALHDGTDVIASSSQVDARRHGELLLPAVDR FT VLAEAGLRLDAVTAVVAGIGPGPYTGLRVGLMTADAFGLALGVPVHGVCTLDGLAFAAD FT LEGPFVVATDARRKEVYWARYADSRTRLTDPAVDRPADIAGQVAGLPAVGAGALLYPDT FT FPRAHEPEHVSAAALARLAAEKLAAGEELPAPRPLYLRRPDAQVPKNYKVVTPK" FT CDS 85484..86017 FT /transl_table=11 FT /gene="SCO4751" FT /gene_synonym="SC6G4.29" FT /product="putative acetyltransferase" FT /note="SC6G4.29, probable acetyltransferase, len: 177 aa; s FT imilar to e.g. RIMI_ECOLI ribosomal-protein-alanine acetyl FT transferase (148 aa), fasta scores; opt: 166 z-score: 257.4 FT E(): 4.5e-07, 33.3% identity in 120 aa overlap. Contains Pf FT am match to entry PF00583 Acetyltransf, Acetyltransferase ( FT GNAT) family, score 59.60, E-value 6.7e-14" FT /db_xref="GOA:O86792" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:O86792" FT /protein_id="CAA20407.1" FT /translation="MTEPATAESAPAALREMRWWDIDPVLRMERELFPEDAWSRGMFWS FT ELAHARGPGATRRYLVAEEDGHVVGYAGLVTSGEQADVQTIAVARDHWGTGLGARLLTE FT LLRAATDFECTEVLLECRVDNTRAQRLYERFGFEPIGFRRGYYQPGNVDALVMRLTDPS FT TSVPGTERGTENHG" FT misc_feature 85523..85897 FT /note="Pfam match to entry PF00583 Acetyltransf, Acetyltran FT sferase (GNAT) family, score 59.60, E-value 6.7e-14" FT RBS 85995..85998 FT /note="possible RBS upstream of gcp" FT CDS 86010..87134 FT /transl_table=11 FT /gene="SCO4752" FT /gene_synonym="gcp" FT /product="putative O-sialoglycoprotein endopeptidase" FT /note="SC6G4.30, gcp, probable O-sialoglycoprotein endopept FT idase, len: 374 aa; similar to many e.g. GCP_PASHA Pasteure FT lla haemolytica O-sialoglycoprotein endopeptidase (EC 3.4.2 FT 4.57) (325 aa), fasta scores; opt: 871 z-score: 526.3 E(): FT 4.7e-22, 46.5% identity in 316 aa overlap" FT /db_xref="GOA:O86793" FT /db_xref="InterPro:IPR017861" FT /db_xref="UniProtKB/Swiss-Prot:O86793" FT /protein_id="CAA20408.1" FT /translation="MADSRDEPLVLGIETSCDETGVGVVRGTTLLADAVASSVDEHARF FT GGVVPEVASRAHLEAMVPTIDRALKEAGVSARDLDGIAVTAGPGLAGALLVGVSAAKAY FT AYALGKPLYGVNHLASHICVDQLEHGALPEPTMALLVSGGHSSLLLSTDITSDVRPLGA FT TIDDAAGEAFDKIARVLNLGFPGGPVIDRYAREGDPNAIAFPRGLTGPRDAAYDFSFSG FT LKTAVARWIEAKRAAGEEVPVRDVSASFQEAVVDVLTRKAVRACKDEGVDHLMIGGGVA FT ANSRLRALAQERCEAAGIRLRVPRPKLCTDNGAMVAALGAEMVARNRAASDWDLSADSS FT LPVTEPHVPGQGHPHGHPHGHDHVHEVSKENLYS" FT RBS 87114..87119 FT /note="possible RBS upstream of SC6G4.31" FT CDS 87131..87403 FT /transl_table=11 FT /gene="SCO4753" FT /gene_synonym="SC6G4.31" FT /product="hypothetical protein" FT /note="SC6G4.31, unknown, len: 90 aa" FT /db_xref="UniProtKB/TrEMBL:O86794" FT /protein_id="CAA20409.1" FT /translation="MTVALMWEARAVPGRGGELLAWARRQELPRRPLRRETLRAPQDRV FT LVITWWDAGYDAALPELPEPDGNLVTRAVHRWRFESVEDDDLRGE" FT CDS 87488..88555 FT /transl_table=11 FT /gene="SCO4754" FT /gene_synonym="SC6G4.32" FT /product="putative transcriptional regulator" FT /note="SC6G4.32, probable transcriptional regulator, len: FT 355 aa; similar to many members of the lacI family e.g. FT RBSR _ECOLI ribose operon repressor (329 aa), fasta scores; FT opt: 588 z-score: 718.4 E(): 9.4e-33, 34.8% identity in 305 FT aa overlap. Contains PS00356 Bacterial regulatory proteins, FT lacI family signature, helix-turn-helix motif at aa 20-41 FT (Score 2255, +6.87 SD) and Pfam matches to entry PF00356 FT lacI, Bacterial regulatory proteins, lacI family, score FT 36.90, E -value 6.1e-09 and to entry PF00532 FT Peripla_BP_like, Periplasmic binding proteins and LacI FT family, score 127.80, E-va lue 2e-34" FT /db_xref="GOA:O86795" FT /db_xref="HSSP:1UXC" FT /db_xref="InterPro:IPR001761" FT /db_xref="UniProtKB/TrEMBL:O86795" FT /protein_id="CAA20410.1" FT /translation="MTSPQPAETRTQKRSAQTATLAEIAREAGVSAPTVSKVLNGRADV FT APSTRARVEELLRTHGYRRRRAESTRSPLIDLVFHELESAWAMEVIRGVENVARDAGLS FT VVLSESAGRLTPGRTWADQVAARRPHGVILVLSGLDESQRALLTSRSIPFVVMDPAGDP FT GADVPSIGATNWQGGLAATRHLVDLGHTRIGAISGPTRMMCSRARVDGYRAALETAGLP FT VDPGLIVTGDFHHEAGYRQGLELLRRPDRPTAVFAGNDLQALGLYEAARELGLRIPHDL FT SVVGFDDLPVARWVGPPLTTVRQPLMEMAEAAARLVLDLGREDRSSTATRVELATSLEV FT RSSTAPPREGRDVAG" FT misc_feature 87536..87619 FT /note="Pfam match to entry PF00356 lacI, Bacterial regulato FT ry proteins, lacI family, score 36.90, E-value 6.1e-09" FT misc_feature 87548..87604 FT /note="PS00356 Bacterial regulatory proteins, lacI family s FT ignature" FT misc_feature 87698..88426 FT /note="Pfam match to entry PF00532 Peripla_BP_like, Peripla FT smic binding proteins and LacI family., score 127.80, E-val FT ue 2e-34" FT CDS 88654..89736 FT /transl_table=11 FT /gene="SCO4755" FT /gene_synonym="SC6G4.33" FT /product="putative transcriptional regulator" FT /note="SC6G4.33, possible transcriptional regulator, len: FT 360 aa; similar to many putative membrane bound regulators FT e.g. TR:P96499 (EMBL:U56901) B. subtilis putative FT transcriptional regulator (391 aa), fasta scores; opt: 333 FT z-score: 2 78.7 E(): 2.9e-08, 28.1% identity in 352 aa FT overlap. Also similar to SC1C3.08c (E(): 0, 52.7% identity FT in 334 aa overlap. Contains possible transmembrane domain FT near N-terminus" FT /db_xref="InterPro:IPR004474" FT /db_xref="UniProtKB/TrEMBL:O86796" FT /protein_id="CAA20411.1" FT /translation="MGTRTGRDGQGGGGRMAARGGQDGRGGRRKALKAAGVALVGSLLL FT GAGAAGWAYWHLNGNIRSVDINGALGDDRPARPATVPSASPSASPVPTGALNILVLGSD FT SRTGEQNQELGGGDSGGARSDTAMVVHLDAGRTAATVVSIPRDTLVERPSCPLPSGGTT FT RAASGAMFNTAYELGGPVCAVKTVESLTGVRMDHYVEVDFSGFADLVDALGGVTVTTDV FT DIDDDKSHLHLDAGTHHLDGTEALGLARTRYGLAGGSDLARIELQHKLVKALLQQVSAT FT DLLTDPAKLYQVADALTGSLTTDTGLDSLGELTNLGRSLGDLAADDVRTLTMPVLPAPS FT DPNRVVADQPDAAELWESLR" FT RBS 89837..89841 FT /note="possible RBS upstream of SC6G4.34" FT CDS 89847..90203 FT /transl_table=11 FT /gene="SCO4756" FT /gene_synonym="SC6G4.34" FT /product="conserved hypothetical protein" FT /note="SC6G4.34, unknown, len: 118 aa; similar to a hypothe FT tical protein from Rhizobium meliloti TR:Q52996 (EMBL:L3926 FT 5) (100 aa), fasta scores; opt: 130 z-score: 222.8 E(): 3.8 FT e-05, 28.8% identity in 73 aa overlap" FT /db_xref="InterPro:IPR005545" FT /db_xref="UniProtKB/TrEMBL:O86797" FT /protein_id="CAA20412.1" FT /translation="MPRYLSLIRIEESDAVPGGPSPELIQRMEKLMEEMTKAGVLLDTA FT GLTPTSQGTRVHYEGGQISVTDGPFTETKEVIGGYSLLQAKDRAEAVEWTKRFLKVHEE FT YWTVTCEVRELMEG" FT CDS 90266..91525 FT /transl_table=11 FT /gene="SCO4757" FT /gene_synonym="SC6G4.35" FT /product="conserved hypothetical protein" FT /note="SC6G4.35, unknown, len: 419 aa; similar to hypotheti FT cal protein from Rhizobium meliloti TR:Q52997 (EMBL:L39265) FT (66 aa, partial) opt: 154 z-score: 162.6 E(): 0.086, 40.0% FT identity in 50 aa overlap. N-terminus is weakly similar to FT several sigma factors e.g. CARQ_MYXXA RNA polymerase sigma FT factor carQ (174 aa), fasta scores; opt: 153 z-score: 172. FT 4 E(): 0.024, 29.8% identity in 161 aa overlap" FT /db_xref="GOA:O86798" FT /db_xref="HSSP:1OR7" FT /db_xref="InterPro:IPR007627" FT /db_xref="UniProtKB/TrEMBL:O86798" FT /protein_id="CAA20413.1" FT /translation="MEAQPAAAFETVFRIESPRVIAGVARLVRDVGIAEELTQDALVAA FT LEQWPRDGVPDNPGAWLMTTARRRAVDLIRRRETYARKLAEIGRDLPVSAPPPEEPADP FT EDIDDDLLRLVFTACHPVLSAEARIALTLRLLGGLTTPEIARARLVPEPTVAQRIVRAK FT RTLARKNVAFEVPYGPDRAARLDSVLEVIYLIFNEGYAATAGDDWLRPALCEDALRLAR FT VLSALMPKEPEVHGLTALLEFQSSRTAARTAPDGEPVLLRDQNRHRWNRLLITRGVTAL FT GHAHATTGAKGPGPYALQAAIAACHATARTYEETDWPRIATLYGLLAARAPSPVVELNR FT AVAVSMAAGPAPALALVDALAAEPALRDYHLLPSVRGDLLLRLDRTAEAREEFERAASL FT TRNARERALLRRRAQEATGG" FT CDS complement(91522..92802) FT /transl_table=11 FT /gene="SCO4758" FT /gene_synonym="SC6G4.36c" FT /product="conserved hypothetical protein" FT /note="SC6G4.36c, similar to hypothetical proteins e.g. M. FT tuberculosis TR:O53284 (EMBL:AL021287) MTV012.52c (358 aa) FT , fasta scores; opt: 545 z-score: 329.5 E(): 4.1e-11, 36.2% FT identity in 354 aa overlap" FT /db_xref="UniProtKB/TrEMBL:O86799" FT /protein_id="CAA20414.1" FT /translation="MYDCSHGAGSSQSPAAEPGPTPRRRHTIHRLAHNDPVNDLDFLLT FT PEGRALLDEVRDTDPVRELAVATRLRRTHPAELVSAALGQARLRQRAVAKFGAEDAGRM FT FFTPNGVEQSTRASVAAYRAGRFAALGVASVADLCCGIGGDAIALARAGIRVLAVDRDP FT VTAAAARANADALGLAGLIEVREADVTEVDTEAYDAVFVDPARRGGRGRIFDPEAYSPP FT LSWAVRAARTASRAAALKVAPGIPHEAVPEDAEAEWISDGGDVKEAVLWFGAGAAPGAV FT RATLLPGPRTLPGTGLPDPEVRTPGRYLYEPDGAVIRAHLVAEVAAQVGGGLLDATIAY FT VTADELLPTPYATAYEITDRMPFNVKKLKALLRERGVGTLTVKKRGSAVEPEELRRKVK FT PQGPNSATVFLTRVAGAPTMLVGHPAR" FT CDS 92830..93705 FT /transl_table=11 FT /gene="SCO4759" FT /gene_synonym="SC6G4.37" FT /product="putative secreted protein" FT /note="SC6G4.37, probable secreted protein, len: 264 aa; FT contains possible N-terminal signal sequence. Similar to FT down stream gene SC6G4.38 (E(): 3.9e-19, 38.7% identity in FT 248 aa overlap)" FT /db_xref="GOA:O86800" FT /db_xref="InterPro:IPR002509" FT /db_xref="UniProtKB/TrEMBL:O86800" FT /protein_id="CAA20415.1" FT /translation="MSRASRATTALAVAALAAGCAQGEDQSVRGAPGQQAPPARAVDGA FT AKAREARAALAAAAKRWKLDKVPLTAPAPPAKKPEIEAREGFEVDGQEEDGLPPVFTTV FT PTKEKVVFLTIDDGAEKDPAFLRMMSELKIPYTVFLTDEEIKDDYGYFKKMQARGITLN FT NHTLSHPYLPGLSYEDQKREICGMQDVMEKHYGKRPVLFRPPYGNYNRDTLRAAKSCGI FT KYAPIWSEEVYVDHWEYREWDQDLHPGDIVLTHFRGENDWDGTMTDMVRRFLDRITADG FT YAVARLEDYL" FT RBS 93690..93694 FT /note="possible RBS upstream of SC6G4.38" FT CDS 93702..94451 FT /transl_table=11 FT /gene="SCO4760" FT /gene_synonym="SC6G4.38" FT /product="putative secreted protein" FT /note="SC6G4.38, probable secreted protein, len: 249 aa; FT slight similarity to S. lividans TR:Q54413 (EMBL:M64552) FT acetyl-xylan esterase precursor (335 aa), fasta scores; FT opt: 16 3 z-score: 197.4 E(): 0.00099, 28.9% identity in FT 180 aa overlap. Contains N-terminal signal sequence" FT /db_xref="GOA:P40179" FT /db_xref="InterPro:IPR002509" FT /db_xref="UniProtKB/Swiss-Prot:P40179" FT /protein_id="CAA20416.1" FT /translation="MRRGRSRPAGAAPAALLLPLLLLLPLTGCDRLAAAPAEHAAAAGD FT PAQDADRGRRLPPVVDHVRTDDPVVFLTYDDGAERDPAFVGLIRERRLPVTLFLTDTVA FT GPAYGDLARLRPFGASLQNHTLDHRSLRGLPHAGQRAEICGQQTKLRSRFGVRAHLFRP FT PHGTYDTTTLRAAADCGITALVLWRATLDADGALTYTRGDHRLHPGDIVAVDPDHPTAA FT NLAARTERLLETIEEQGLRVGNLENYL" FT misc_feature 94062..97063 FT /note="99.4% match to SCGROEL X75206 S.coelicolor groES and FT groEL1 genes for GroES and GroEL1 proteins from 1 to 3000" FT RBS 94775..94780 FT /note="possible RBS upstream of groES" FT CDS 94787..95095 FT /transl_table=11 FT /gene="SCO4761" FT /gene_synonym="groES" FT /product="10 kD chaperonin cpn10" FT /note="SC6G4.39, groES, 10 kD chaperonin cpn10, len: 102 aa FT ; identical to CH10_STRCO (102 aa) and highly similar to ma FT ny e.g. CH10_BACSU (94 aa), fasta scores; opt: 353 z-score: FT 567.4 E(): 2.4e-24, 54.3% identity in 92 aa overlap. Cont FT ains PS00681 Chaperonins cpn10 signature and Pfam match to FT entry PF00166 cpn10, Chaperonins 10 Kd subunit, score 200.6 FT 0, E-value 2.4e-56" FT /db_xref="GOA:P0A345" FT /db_xref="HSSP:1HX5" FT /db_xref="InterPro:IPR018369" FT /db_xref="UniProtKB/Swiss-Prot:P0A345" FT /protein_id="CAA20417.1" FT /translation="MTTTSSKVAIKPLEDRIVVQPLDAEQTTASGLVIPDTAKEKPQEG FT VVLAVGPGRFEDGNRLPLDVSVGDVVLYSKYGGTEVKYNGEEYLVLSARDVLAIVEK" FT misc_feature 94808..95089 FT /note="Pfam match to entry PF00166 cpn10, Chaperonins 10 Kd FT subunit, score 200.60, E-value 2.4e-56" FT misc_feature 94814..94888 FT /note="PS00681 Chaperonins cpn10 signature" FT RBS 95213..95216 FT /note="possible RBS upstream of groEL1" FT CDS 95229..96854 FT /transl_table=11 FT /gene="SCO4762" FT /gene_synonym="groEL1" FT /product="60 kD chaperonin cpn60" FT /note="SC6G4.40, groEL1, 60 kD chaperonin cpn60, len: 541 a FT a; 99.6% identical to CH61_STRCO (539 aa) and highly simila FT r to many e.g.CH60_BACSU (543 aa), fasta scores; opt: 2152 FT z-score: 2429.5 E(): 0, 62.6% identity in 537 aa overlap. C FT ontains PS00296 Chaperonins cpn60 signature and Pfam match FT to entry PF00118 cpn60_TCP1, Chaperonins cpn60 and TCP-1, s FT core 759.20, E-value 1.7e-224" FT /db_xref="GOA:P40171" FT /db_xref="HSSP:1IOK" FT /db_xref="InterPro:IPR002423" FT /db_xref="UniProtKB/Swiss-Prot:P40171" FT /protein_id="CAA20418.1" FT /translation="MAKILKFDEDARRALERGVNKLADTVKVTIGPKGRNVVIDKKFGA FT PTITNDGVTIAREVEVEDPYENLGAQLVKEVATKTNDIAGDGTTTATVLAQALVREGLK FT NVAAGASPALLKKGIDAAVAAVSEDLLATARPIDEKSDIAAVAALSAQDQQVGELIAEA FT MDKVGKDGVITVEESNTFGLELDFTEGMAFDKGYLSPYFVTDQERMEAVLDDPYILINQ FT GKISSIADLLPLLEKVIQANASKPLLIIAEDLEGEALSTLVVNKIRGTFNAVAVKAPGF FT GDRRKAMLQDMAVLTGATVISEEVGLKLDQVGLEVLGTARRITVTKDDTTIVDGAGKRD FT EVQGRIAQIKAEIENTDSDWDREKLQERLAKLAGGVCVIKVGAATEVELKERKHRLEDA FT ISATRAAVEEGIVSGGGSALVHAVKVLEGNLGKTGDEATGVAVVRRAAVEPLRWIAENA FT GLEGYVITSKVADLDKGQGFNAATGEYGDLVKAGVIDPVKVTRSALENAASIASLLLTT FT ETLVVEKKEEEEPAAGGHSHGHSH" FT misc_feature 95292..96803 FT /note="Pfam match to entry PF00118 cpn60_TCP1, Chaperonins FT cpn60 and TCP-1, score 759.20, E-value 1.7e-224" FT misc_feature 96441..96476 FT /note="PS00296 Chaperonins cpn60 signature" FT CDS complement(97094..98335) FT /transl_table=11 FT /gene="SCO4763" FT /gene_synonym="SC6G4.41c" FT /product="hypothetical protein" FT /note="SC6G4.41c, unknown, len: 413 aa" FT /db_xref="UniProtKB/TrEMBL:O86802" FT /protein_id="CAA20419.1" FT /translation="MNAGTGDRGELFVDGIDGRRTDGVRPGRGAVTGGGTVLFSDAPGG FT GSPSAAPASARPGTADTAGAASVPHARHTPRPRPGGAPARARRAGRWAKVAQRIVPDDL FT QPEVLRVELTELGDAFRAYQRRPEPDLAVLAGLHDRKARAFALWADVTGDASLREEADR FT AAAAARTTREMDANRRGVPVDGEGPVVERLLTRGQGVHARNVLAHVRTGAPFPDAEPRL FT AVLMLTLRAARTGTGNVTGQDLGGWLQGDAERVLRELVDVGWLLLPQDVTADDALMSRP FT EEPAQITVSTLIPTQPRPFFFGKVTRARLSGWAQKVVGDRKLRKKKAGAATRLLAVYTA FT AHSRPDGCLGAAGEDAGPALDEVAQFCGLRPEEVAGHAGLLVAAGWLAEDADTTDGRLR FT GRLAERVLPLSGLL" FT RBS complement(98346..98349) FT /note="possible RBS upstream of SC6G4.41c" FT CDS complement(98478..99251) FT /transl_table=11 FT /gene="SCO4764" FT /gene_synonym="SC6G4.42c" FT /product="putative dehydrogenase" FT /note="SC6G4.42c, probable dehydrogenase, len: 257 aa; simi FT lar to many members of the short-chain dehydrogenases/reduc FT tases family e.g. TR:Q54190 (EMBL:D14040) S. galilaeus keto FT acyl reductase aknIII (261 aa), fasta scores; opt: 350 z-sc FT ore: 438.4 E(): 3.5e-17, 33.5% identity in 233 aa overlap. FT Contains Pfam match to entry PF00106 adh_short, Alcohol/oth FT er dehydrogenases, short chain type, score 158.00, E-value FT 1.6e-43" FT /db_xref="GOA:O86803" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:O86803" FT /protein_id="CAA20420.1" FT /translation="MTTALITGSTAGLGAAFARRLAADGHDLVLVARDTERLRGQATEL FT HDRHGIEAEVLTADLSADPGIDAVAARLSDRRNPVDLLVNNAGFGNKGRFLDVPMADEL FT TMLKVHCEAVLRLTSAAVEAMRERGRGGVVNVASVAAFVPRGTYGASKAWVVQFTQGVA FT KDLAGSGVRLMALAPGFVRTEFHERAGMGTDNIPNWMWLDADNVVAAALADLSRGRSLS FT IPDPRYKTLMGAAKLVPRGLLGGITSRTGRKYGPQ" FT misc_feature complement(98700..99248) FT /note="Pfam match to entry PF00106 adh_short, Alcohol/other FT dehydrogenases, short chain type, score 158.00, E-value 1. FT 6e-43" FT CDS complement(99306..100007) FT /transl_table=11 FT /gene="SCO4765" FT /gene_synonym="SC6G4.43c" FT /product="conserved hypothetical protein" FT /note="SC6G4.43c, unknown, len: 233 aa; similar to hypothet FT ical proteins e.g. M. tuberculosis TR:P95151 (EMBL:Z83859) FT MTCY359.09 (251 aa), fasta scores; opt: 716 z-score: 609.7 FT E(): 1e-26, 54.4% identity in 215 aa overlap" FT /db_xref="GOA:O86804" FT /db_xref="InterPro:IPR015808" FT /db_xref="UniProtKB/TrEMBL:O86804" FT /protein_id="CAA20421.1" FT /translation="MAYRSGMHPSAMRLLSVNLGRAKAVPYTDQPEGVTGIDKRPADGP FT VRVAVPGSEGFGASGLAGDTVCDTRHHGGDEQAVYAMAREDLDDWERTLGRELPNGAFG FT ENLTTTGLDLTGALIGERWRVGAELLLELTSGRIPCRTFQGHMGEPRWVKRFMEKGAPG FT AYFRVLEPGEIRAGDPVRIVHRPSHEVTVALQFRAVTTQRELLPRLLAAGGALHPEALA FT TARKYVAEYGA" FT CDS 100071..100991 FT /transl_table=11 FT /gene="SCO4766" FT /gene_synonym="SC6G4.44" FT /product="putative transcriptional regulator" FT /note="SC6G4.44, probable transcriptional regulator, len: FT 306 aa; similar to many members of the lysR family e.g. FT CYNR_ ECOLI cyn operon transcriptional activator (299 aa), FT fasta scores; opt: 371 z-score: 524.3 E(): 5.8e-22, 30.3% FT identity in 307 aa overlap. Contains PS00044 Bacterial FT regulatory proteins, lysR family signature, FT helix-turn-helix motif at aa 18-39 (Score 1603, +4.65 SD) FT and Pfam match to entry PF0 0126 HTH_1, Bacterial FT regulatory helix-loop-helix proteins, lysR family, score FT 161.30, E-value 1.6e-44" FT /db_xref="GOA:O86805" FT /db_xref="HSSP:1IXC" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:O86805" FT /protein_id="CAA20422.1" FT /translation="MIEARHLRVLRAVASTGSFSAAGRELGCTQPAVSQQMKALESSVG FT TPLLVRTGREMRLTQAGEALVRHAAGIIAGLTAAEEEVAAIAGLRAGRVRLVSFPSGSS FT TLVPTALAALRAAHPGTRVFLEESEPPKSVELLREGDCDVALAFRYEGAAGAEEWDDLV FT VRPLLTDRLVALVPEGHRLARSEGVGSVAIGELARESWIAGCPRCRGQLVEVCEGAGFT FT PRIDFATDDYPAVVGLVGAGLGVAVLPQLAVDSVRPRGVRTVTLEPAVRREIVALTLPD FT LAQVPAVTATLDELARAGARQSATR" FT misc_feature 100080..100508 FT /note="Pfam match to entry PF00126 HTH_1, Bacterial regulat FT ory helix-loop-helix proteins, lysR family, score 161.30, E FT -value 1.6e-44" FT misc_feature 100122..100214 FT /note="PS00044 Bacterial regulatory proteins, lysR family s FT ignature" FT CDS complement(101057..101395) FT /transl_table=11 FT /gene="SCO4767" FT /gene_synonym="SC6G4.45c" FT /product="putative regulatory protein" FT /note="SC6G4.45c, probable regulatory protein, len: 112 aa; FT similar to TR:Q53963 (EMBL:X62287) S.coelicolor regulatory FT protein WhiB (87 aa), fasta scores; opt: 201 z-score: 352. FT 1 E(): 2.3e-12, 49.3% identity in 71 aa overlap" FT /db_xref="InterPro:IPR003482" FT /db_xref="UniProtKB/TrEMBL:O88103" FT /protein_id="CAA20423.1" FT /translation="MADFSRLPGPNADLWDWQLLAACRGVDSSLFFHPEGERGAARSAR FT ENSAKEVCMRCPVRAECAAHALAVREPYGVWGGLTEDEREELMGRARNRLVAATASASA FT GGEAAGPH" FT RBS complement(101403..101408) FT /note="possible RBS upstream of SC6G4.45c" FT RBS 101766..101770 FT /note="possible RBS upstream of SC6G4.46" FT CDS 101777..102388 FT /transl_table=11 FT /gene="SCO4768" FT /gene_synonym="SC6G4.46" FT /product="putative two-component regulator" FT /note="SC6G4.46, probable two-component regulator, len: 203 FT aa; similar to many members of the luxR family e.g. FT DEGU_BACSU transcriptional regulatory protein DegU (229 FT aa), fasta scores; opt: 229 z-score: 546.3 E(): 3.4e-23, FT 30.9% identi ty in 223 aa overlap. Contains PS00622 FT Bacterial regulatory proteins, luxR family signature and FT Pfam matchs to entry PF00072 response_reg, Response FT regulator receiver domain, score 108.40, E-value 1.4e-28 FT and to entry PF00196 GerE, Bacterial regulatory proteins, FT luxR family, score 65.60, E-value 1e-15" FT /db_xref="GOA:O88121" FT /db_xref="HSSP:1FSE" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:O88121" FT /protein_id="CAA20424.1" FT /translation="MTSVLVCDDSPLAREALRRAVATVPGVERVTTAANGEEVLRRWGA FT DRSDLILMDVRMPGLGGVETVRRLLSADPGARIIMLTVAEDLDGVALAVAAGARGYLHK FT DASRAELRATVTQALADPTWRLAPRRLRSAEMGAAPTLTAREIQVLEGMSHGRSNAEIG FT RELFLSEDTVKTHARRLFKKLGASDRAHAVALGFRWGLVR" FT misc_feature 101780..102121 FT /note="Pfam match to entry PF00072 response_reg, Response r FT egulator receiver domain, score 108.40, E-value 1.4e-28" FT misc_feature 102191..102385 FT /note="Pfam match to entry PF00196 GerE, Bacterial regulato FT ry proteins, luxR family, score 65.60, E-value 1e-15" FT misc_feature 102242..102325 FT /note="PS00622 Bacterial regulatory proteins, luxR family s FT ignature" FT misc_feature 102343..103289 FT /note="previously sequenced fragment EMBL:AJ010601 FT Streptomyces coelicolor A3(2) DNA for whiD and whiK loci" FT CDS 102670..103257 FT /transl_table=11 FT /gene="SCO4769" FT /gene_synonym="SCD63.01" FT /product="ECF sigma factor" FT /note="SCD63.01, ECF sigma factor, len: 195 aa; identical FT to previously sequenced TR:O86843 (EMBL:AJ010601) FT Streptomyces coelicolor ECF sigma factor, 195 aa" FT /db_xref="GOA:Q9L0I8" FT /db_xref="InterPro:IPR007627" FT /db_xref="UniProtKB/TrEMBL:Q9L0I8" FT /protein_id="CAB82008.1" FT /translation="MRDDDAPPDQGTVGGLVHRAVDGDEQATHDLLAHVHPLALRYCRT FT RLSRLPGDARHFVEDLAQEVCVAVLLALPRYKDTGRPFEAFVFAIAAHKVADLQRAAMR FT HPGSTAVPSDEMPERPDDSLGPEERALLNSDAAWAKKLLANLPENQRELLLLRIAVGLT FT AEETGQMLGMSPGAVRVAQHRALSRLRALAEQ" FT misc_feature 103367..103487 FT /note="previously sequenced DNA fragment EMBL:AJ010601 FT Streptomyces coelicolor A3(2) DNA for whiD and whiK loci" FT CDS 103397..104902 FT /transl_table=11 FT /gene="SCO4770" FT /gene_synonym="SCD63.02" FT /gene_synonym="guaB" FT /product="inosine 5' monophosphate dehydrogenase" FT /note="SCD63.02, guaB, inosine 5' monophosphate FT dehydrogenase, len: 501 aa; highly similar to previously FT sequenced TR:O86844 (EMBL:AJ010601) Streptomyces coelicolor FT inosine 5' monophosphate dehydrogenase, 523 aa; fasta FT scores: opt: 2626 z-score: 2896.3 E(): 0; 84.9% identity in FT 509 aa overlap. Contains Pfam matches to entries PF01574 FT IMPDH_N, IMP dehydrogenase / GMP reductase N terminus, 2x FT PF00571 CBS, CBS domain and PF00478 IMPDH_C, IMP FT dehydrogenase / GMP reductase C terminus and match to FT Prosite entry PS00487 IMP dehydrogenase / GMP reductase FT signature" FT /db_xref="GOA:Q9L0I7" FT /db_xref="HSSP:1B3O" FT /db_xref="InterPro:IPR018529" FT /db_xref="UniProtKB/TrEMBL:Q9L0I7" FT /protein_id="CAB82009.1" FT /translation="MTANVDGVPEKFATLGLTYDDVLLLPGASAVLPNAVDTSSRISRN FT VRVNIPLLSAAMDKVTESRMAISMARQGGVGVLHRNLSIEDQANQVDLVKRSESGMVAN FT PITIHPDATLGEADALCAKFRISGVPVTDGAGKLLGIVTNRDMAFETDRSRQVREVMTP FT MPLVTGQVGISGVDAMELLRRHKIEKLPLVDGDGILKGLITVKDFVKAEQYPHAAKDAK FT GRLLVGAAVGASPEALDRAQALAEAGVDFLVVDTSHGHNSNALSWMSKIKSSVGIDVVG FT GNVATRDGAQALIDAGVDGIKVGVGPGSICTTRVVAGIGVPQVTAIYEASLAARAAGVP FT LIGDGGLQYSGDIGKALAAGADTVMLGSLLAGCEESPGELQFINGKQFKSYRGMGSLGA FT MQSRGQGRSYSKDRYFQAEVASDDKLVPEGIEGQVPYRGPLANVLHQLVGGLRQTMGYV FT GAATIEEMESKGRFVRITSAGLKESHPHDIQMTVEAPNYSRSK" FT misc_feature 103424..103687 FT /note="Pfam match to entry PF01574 IMPDH_N, IMP FT dehydrogenase / GMP reductase N terminus, score 175.90, FT E-value 6.8e-49" FT misc_feature 103675..104753 FT /note="previously sequenced DNA fragment EMBL:AJ010601 FT Streptomyces coelicolor A3(2) DNA for whiD and whiK loci" FT misc_feature 103691..103852 FT /note="Pfam match to entry PF00571 CBS, CBS domain, score FT 46.80, E-value 5e-10" FT misc_feature 103874..104035 FT /note="Pfam match to entry PF00571 CBS, CBS domain, score FT 40.00, E-value 5.4e-08" FT misc_feature 104123..104806 FT /note="Pfam match to entry PF00478 IMPDH_C, IMP FT dehydrogenase / GMP reductase C terminus, score 338.30, FT E-value 8.7e-98" FT misc_feature 104297..104335 FT /note="PS00487 IMP dehydrogenase / GMP reductase signature" FT misc_feature 104767..105282 FT /note="previously sequenced DNA fragment EMBL:AJ010601 FT Streptomyces coelicolor A3(2) DNA for whiD and whiK loci" FT CDS 105043..106167 FT /transl_table=11 FT /gene="SCO4771" FT /gene_synonym="SCD63.03" FT /product="putative inosine-5'-monophosphate dehydrogenase" FT /note="SCD63.03, possible inosine-5'-monophosphate FT dehydrogenase, len: 374 aa; N-terminal region identical to FT previously sequenced TR:O86845 (EMBL:AJ010601) Streptomyces FT coelicolor hypothetical 38.9 kD protein (fragment), 84 aa FT and whole CDS similar to SW:IMDH_ECOLI (EMBL:X02209) FT Escherichia coli inosine-5'-monophosphate dehydrogenase (EC FT 1.1.1.205) GuaB, 488 aa; fasta scores: opt: 275 z-score: FT 311.9 E(): 6.1e-10; 29.0% identity in 376 aa overlap. FT Contains Pfam matches to entries PF01574 IMPDH_N, IMP FT dehydrogenase / GMP reductase N terminus PF00478 IMPDH_C, FT IMP dehydrogenase / GMP reductase C terminus" FT /db_xref="GOA:Q9L0I6" FT /db_xref="HSSP:1B3O" FT /db_xref="InterPro:IPR005992" FT /db_xref="UniProtKB/TrEMBL:Q9L0I6" FT /protein_id="CAB82010.1" FT /translation="MTEIEIGRGKRGRRAYAFDDIAVVPSRRTRDPKEVSIAWQIDAYR FT FELPFLAAPMDSVVSPATAIRIGELGGLGVLNLEGLWTRHEDPQPLLDEIAELDTDNAT FT RRLQEIYAAPIKEELIGQRIKEVRDSGVVTAAALSPQRTAQFSKAVVDAGVDIFVIRGT FT TVSAEHVSGSHEPLNLKQFIYELDVPVIVGGCATYTAALHLMRTGAAGVLVGFGGGAAH FT TTRNVLGIQVPMATAVADVAAARRDYMDESGGRYVHVIADGGVGWSGDLPKAIACGADS FT VMMGSPLARATDAPGRGNHWGMEAVNEELPRGKKVDLGTVGTIEEILTGPSRNPDGSMN FT FFGALRRAMATTGYSELKEFQRVEVTVADSQHRR" FT misc_feature 105067..105276 FT /note="Pfam match to entry PF01574 IMPDH_N, IMP FT dehydrogenase / GMP reductase N terminus, score 1.10, FT E-value 0.00079" FT misc_feature 105487..106134 FT /note="Pfam match to entry PF00478 IMPDH_C, IMP FT dehydrogenase / GMP reductase C terminus, score 44.60, FT E-value 1.1e-09" FT misc_feature 105792..105908 FT /note="previously sequenced DNA fragment EMBL:AJ010601 FT Streptomyces coelicolor A3(2) DNA for whiD and whiK loci" FT CDS 106499..107719 FT /transl_table=11 FT /gene="SCO4772" FT /gene_synonym="SCD63.04" FT /product="putative transposase" FT /note="SCD63.04, possible transposase, len: 406 aa; similar FT to TR:Q9X8Z6 (EMBL:AL078610) Streptomyces coelicolor FT putative transposase SCH35.10, 407 aa; fasta scores: opt: FT 513 z-score: 604.0 E(): 3.2e-26; 29.9% identity in 408 aa FT overlap. Contains Pfam match to entry PF01385 FT Transposase_2, Probable transposase" FT /db_xref="InterPro:IPR010095" FT /db_xref="UniProtKB/TrEMBL:Q9L0I5" FT /protein_id="CAB82011.1" FT /translation="MAQAGADETGRHVRYTYRLRVSSAARASLAAEWGRCRWLWNECVA FT KSRAVHLRNRATGEKATCGPAQLDRMLTEARARTPWLREGSCVPQQQVIRDFGRSRAKA FT HKDITEGLPVARRAGMPTWKTRRESPATLNYTRRGFRLKDGRLHLAGGIVLNVVWSREL FT PDEPSSVRVYQDSLGHWYCSFVVPAHVQPLPATGRVLGVDWGVRETATTTSDAHDLPHP FT SHGGKARARLARYDRMMARRRRKKGTAASSGYRAAKRLRAKAYKKVARQRADTGRKWAK FT KVVRDHDAVAVEDFRPKFLARSTMARKAADAAIGATKAALIEMGRKHGRDIRLVHPAYT FT TMDCAQCGARAKHALPLGERTHTCTACGTTSPRDKNSARVMLARAGLNPAGAEGGRPPG FT APLQEAA" FT misc_feature 106586..107413 FT /note="Pfam match to entry PF01385 Transposase_2, Probable FT transposase, score 89.90, E-value 5.1e-23" FT CDS complement(107821..109038) FT /transl_table=11 FT /gene="SCO4773" FT /gene_synonym="SCD63.05c" FT /product="putative nucleotide-sugar dehydrogenase" FT /note="SCD63.05c, probable nucleotide-sugar dehydrogenase, FT len: 405 aa; similar to SW:WECC_ECOLI (EMBL:M87049) FT Escherichia coli UDP-N-acetyl-D-mannosaminuronic acid FT dehydrogenase (EC 1.1.1.-) WecC, 420 aa; fasta scores: opt: FT 565 z-score: 606.3 E(): 2.4e-26; 31.7% identity in 420 aa FT overlap. Contains Pfam match to entry PF00984 UDPG_MGDP_dh, FT UDP-glucose/GDP-mannose dehydrogenase family" FT /db_xref="GOA:Q9L0I4" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9L0I4" FT /protein_id="CAB82012.1" FT /translation="MPADLAVIGLGPYGLPLAQAAVAAGIPTLGYRTGPEADPLTPAEV FT RRMLATGFRTPTGPAGPAELGRVRTAVICAPTPPGADGGLDLTQVEAAARTLAAHMRPH FT TTVILESPVRPGTTEDFLRPLLEQGSGLRAGRDFHLAYSPSRVDPGNRDFTPANTPKVI FT GGLTPACTESAAAFYSRLTDKVVRARGPREAETVQLLETNFRHVNIALVNEMAVLCDDL FT GVDLWDVLRCAETKPFGFHAFRPGPGVGGHSVAQDLTGRAPHSLRMVELAQQVNAQMPR FT YVVQRAAALLNEHGKSARGARILLLGVTYKADLADQQATPAEEIATRLMSMGAAVSYHD FT PHIPSWNVADRPVPRADSLYEAAADADLTILLQQHRTYDLQGLSVKAQLLLDTRGATPT FT GAAHRL" FT misc_feature complement(107860..109032) FT /note="Pfam match to entry PF00984 UDPG_MGDP_dh, FT UDP-glucose/GDP-mannose dehydrogenase family, score 182.20, FT E-value 8.3e-51" FT RBS 109331..109335 FT CDS 109341..111047 FT /transl_table=11 FT /gene="SCO4774" FT /gene_synonym="SCD63.06" FT /product="putative glycerol phosphate dehydrogenase" FT /note="SCD63.06, probable glycerol phosphate dehydrogenase, FT len: 568 aa; similar to SW:GLPD_BACSU (EMBL:M34393) FT Bacillus subtilis aerobic glycerol-3-phosphate FT dehydrogenase (EC 1.1.99.5) GlpD, 555 aa; fasta scores: FT opt: 815 z-score: 910.2 E(): 0; 32.1% identity in 546 aa FT overlap. Contains Pfam match to entry PF01224 FAD_Gly3P_dh, FT FAD-dependent glycerol-3-phosphate dehydrogenase and match FT to Prosite entry PS00978 FAD-dependent glycerol-3-phosphate FT dehydrogenase signature 2" FT /db_xref="GOA:Q9L0I3" FT /db_xref="InterPro:IPR000447" FT /db_xref="UniProtKB/TrEMBL:Q9L0I3" FT /protein_id="CAB82013.1" FT /translation="MRTATLGPAQRAESLAAMAERELDVLVVGAGVVGAGTALDAVTRG FT LSVGLVEARDWASGTSSRSSKLIHGGLRYLEMLDFVLVREALKERGLLLERLAPHLVKP FT VPFLYPLQHKGWERLYAGSGVALYDAMSMARGHGRGLPLHRHLSRRHALRVAPALKKDA FT LVGALQYYDAQMDDARFVATLVRTAAAYGAKVANRARVTSFLREGERVVGARVQDVEAG FT GEYEVRAKQVVNATGVWTDDTQAMVGERGQFHVRASKGIHLVVPKDRIHSSTGLILRTE FT KSVLFVIPWGRHWIIGTTDTDWDLDKAHPAASSADIDYLLEHVNSVLSVPLTRDDVEGV FT YAGLRPLLAGESDATSKLSREHTVAHPVPGLVVVAGGKYTTYRVMAKDAVDEAVHGLDL FT RVADCVTEETPLLGAEGYHAQWNARARIAARTGLHVVRVEHLLNRYGSLTEELLELVAA FT DPSLGEPLTGADDYLRAEVVYAASHEGARHLDDVLTRRTRISIETFDRGTRCAREAAEL FT MAPVLGWDKGQVEREIEHYEKRVEAERESQRQPDDLTADAARLGAPDIAAR" FT misc_feature 109398..111005 FT /note="Pfam match to entry PF01224 FAD_Gly3P_dh, FT FAD-dependent glycerol-3-phosphate dehydrogenase, score FT 675.00, E-value 3.7e-199" FT misc_feature 110466..110498 FT /note="PS00978 FAD-dependent glycerol-3-phosphate FT dehydrogenase signature 2" FT RBS 111138..111142 FT CDS 111148..113301 FT /transl_table=11 FT /gene="SCO4775" FT /gene_synonym="pkaH" FT /gene_synonym="SCD63.07" FT /product="serine/threonine protein kinase" FT /note="SCD63.07, pkaH, serine/threonine protein kinase, FT len: 717 aa; similar to TR:Q9XAI1 (EMBL:AL079348) FT Streptomyces coelicolor putative serine/threonine protein FT kinase SC66T3.32c, 783 aa; fasta scores: opt: 570 z-score: FT 386.8 E(): 4.1e-14; 30.6% identity in 687 aa overlap and to FT SW:PKAA_STRCO (EMBL:D86821) Streptomyces coelicolor FT serine/threonine protein kinase PkaA (EC 2.7.1.-), 543 aa; FT fasta scores: opt: 543 z-score: 370.9 E(): 3.1e-13; 29.8% FT identity in 476 aa overlap. Contains Pfam match to entry FT PF00069 pkinase, Eukaryotic protein kinase domain and FT matches to Prosite entries PS00107 Protein kinases FT ATP-binding region signature and PS00108 Serine/Threonine FT protein kinases active-site signature and possible FT hydrophobic membrane spanning region" FT /db_xref="GOA:Q9L0I2" FT /db_xref="HSSP:1O6Y" FT /db_xref="InterPro:IPR008271" FT /db_xref="UniProtKB/TrEMBL:Q9L0I2" FT /protein_id="CAB82014.1" FT /translation="MSEAERAGTSRTDKSARLLAGRYRLGDVLGRGGMGTVWRAEDETL FT GRTVAVKELRFPGNIDEEEKRRLITRTLREAKAIARIRNNSAVTVYDVVEEDDRPWIVM FT ELVEGKSLAEAIREDGLLEPRRAAEVGLAVLDVLRSAHREGILHRDVKPSNVLIAEDGR FT VVLTDFGIAQVEGDPSITSTGMLVGAPSYISPERARGHKPGPAADLWSLGGLLYAAVEG FT TPPYDRGSAIATLTAVMTENLEEPKNAGPLRDVIYGLLTKDPDQRLDDAGARAMLNKVI FT HAPEQTAGTEPVDATKVVPLPPQPDGRRRRGGGAQGSGGKLGEEAGEKLRGALRSVRKA FT AVGAGAAGAAAASRAKPGDGGRSAAGAAGTPTAHGSTVHGSTAQGSTVRHGSTAQGATA FT HGPAGTAAAPPAPRAGSASGPGASAGTRPGAVGPGAGAANAAGGARSSGWPVVPPPDLP FT ARPVPRAPLTDVVPRRTLIIIAVVVALAVLGTVLALTLGGGDDDKGAEGGNGGKAVASA FT GASGDTKQDEQSGTGTDGSASDPAANGDQTGAPDTAASASGETGGESDDAGKSDDDEDV FT ATTHQGGQGYRIGLPEGWKFASTGSSGDRFTGPRGQKLLVAWTSTPKGDPVADWKSQEQ FT YMVRSNYQKVRIEKVGYRDWNAADWEFTYTDGGTKYRTVDRGFVVNDHQGYALMYTAKA FT ADWGDDLRRDTWRTLSKTFEPKS" FT misc_feature 111214..111951 FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 177.40, E-value 2.3e-49" FT misc_feature 111232..111303 FT /note="PS00107 Protein kinases ATP-binding region FT signature" FT misc_feature 111567..111966 FT /note="BlastN hit to EMBL:AB016932 Streptomyces coelicolor FT gene for protein serine/threonine kinase pkaD, complete FT cds." FT misc_feature 111583..111621 FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT CDS 113475..116414 FT /transl_table=11 FT /gene="SCO4776" FT /gene_synonym="SCD63.08" FT /product="putative serine/threonine protein kinase" FT /note="SCD63.08, possible serine/threonine protein kinase, FT len: 979 aa; similar to TR:O83032 (EMBL:AB16932) FT Streptomyces coelicolor protein serine/threonine kinase FT PhaD, 598 aa; blastp scores: Sum P(2) = 2.4e-24 Identities FT = 123/403 (30%), Positives = 159/403 (39%). Contains 2x FT Pfam match to entry PF00069 pkinase, Eukaryotic protein FT kinase domain and possible hydrophobic membrane spanning FT region. High content in alanine, glycine and proline FT residues" FT /db_xref="GOA:Q9L0I1" FT /db_xref="InterPro:IPR000719" FT /db_xref="UniProtKB/TrEMBL:Q9L0I1" FT /protein_id="CAB82015.1" FT /translation="MDDYAGRVLADRYRLPLPPSDEYELTETRAFDTYSGQEVLVRQVP FT LPEVVEAEVLDTDGLPDGFTARDGGVRHSGRRPTAAGGPRSPADPVVRRAVEAAQAAAA FT VPDHPRLDQVFDVFAEGGSLWIASELVAARPLAALLTEQTLTPYRAAEVASDVLLALRV FT LHSYGWVHRNITARTVLVCDDGRVMLTGLAVGAAEEALCGYDPVPPPPDGEPDGAPERD FT AVSGAGGGVPRAGVFGPGDADPEAARRAAIEARGVGGLPVPGTPVPGTAPAGLAPASLD FT AAADARAARAGAIAAYRAGARAAARIQEAQNGRAALPGARPAPDGATQAGGPGTSGGRP FT GLAPGPGSSYDDDDGAGRPPHGSAPGGARPGHGVEAAGGAPGARPGQGSGRAAFAAGSG FT QAPYAIGPDAASGAPWDEDSVGDPATSGAAVPPGQITDPYGVGTTAWHGATPRTPGDPA FT SSAARPTGDPAFPAPRPAGEPAAGSGPAAGRALPGARPEDTAGSAVPWRETTAGPAARS FT RETASEAAAGPWRAAPPRAADPEREGGPRPAAGWDDLAGRAPGQRNPATALAAERARQT FT RMAVVGPVTERWAPEQAGPVHENWQLAAPIGPATDLWALGALLFRAVQGHAPYPEESTA FT ELVQIVCAEPPAFAEECGPLRPVVESLLRQDPTERIDFEELSGWLRSLVRSAPEPEAGL FT HVISAPPVETGRLPIVRRRGELVRRRRAGLPAHHGRHKRGRAETDRSPRSLGRTLLLLI FT LLAMAGAVAYAMFFMPKNDTNGAGAPDRTGAAGEASQAPPAKSPDAGGESRPDRSSPAP FT DPGASRTAGGSTEPQSNVADGFTLRKDAEGFRVAVAEGWNRTPRNGSGQVVYGKGDFEL FT IVVPGRDRASEFGDDPMAYQRDSEPELASYRASSWATSSGLKTIEVGGRTMAEGQFTWT FT GAGGELYVRNVAVLIDGRYHVVQVRGPEGERDEVTRLFEQASATYQYTR" FT misc_feature 113793..114044 FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 18.20, E-value 0.00057" FT misc_feature 115287..115502 FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 23.30, E-value 2.3e-05" FT misc_feature 115292..115490 FT /note="BlastN hit to EMBL:AB016932 Streptomyces coelicolor FT gene for protein serine/threonine kinase pkaD, complete FT cds." FT misc_feature 116158..118519 FT /note="previously sequenced fragment EMBL:AB016932 FT Streptomyces coelicolor gene for protein serine/threonine FT kinase, complete cds." FT CDS 116551..118350 FT /transl_table=11 FT /gene="SCO4777" FT /gene_synonym="pkaD" FT /gene_synonym="SCD63.09" FT /product="protein serine/threonine kinase" FT /note="SCD63.09, pkaD, protein serine/threonine kinase, FT len: 599 aa; identical to previously sequenced TR:O83032 FT (EMBL:AB016932) Streptomyces coelicolor protein FT serine/threonine kinase PkaD. Contains Pfam match to entry FT PF00069 pkinase, Eukaryotic protein kinase domain and FT matches to Prosite entries PS00107 Protein kinases FT ATP-binding region signature and PS00108 Serine/Threonine FT protein kinases active-site signature and possible FT hydrophobic membrane spanning region" FT /db_xref="GOA:Q9L0I0" FT /db_xref="HSSP:1O6Y" FT /db_xref="InterPro:IPR017442" FT /db_xref="UniProtKB/TrEMBL:Q9L0I0" FT /protein_id="CAB82016.1" FT /translation="MNQMQGRLVAGRYRLGEAIGSGGMGRVWRAHDEVLHRTVAIKELT FT AALYVSESDQAILLARTRGEARAAARINHSAVVTVHDVLEHDGRPWIVMELVEGRSLAD FT AVKEEERVDPREAARVGLWVLRALRAAHTAGVLHRDVKPGNVLLADDGRVLLTDFGIAQ FT IEGDSTITRTGEVVGSVDYLAPERVRGHDPGPSSDLWALGATLYTAVEGRSPFRRTSPL FT TTMQAVVEEEATEPRYAGALAPVISALLRKDPAERPDATEAEHLLAQAAEGRRPDAAQA FT YVPTTRYEGPPRAGDTAVQGMPAGGSGATPYPQAGGSGATPYPPTTGPTGAGPAPTGHT FT RGGYTQVGHTEGGYTAPGYAPAPAVGGAAPGRARRVRMRTLALVVAVAALIGAGTAVVL FT HQRDEGGSSAGADPTQGPTGSAAPSPSPSASATTGKGPGGSVPADWTRRDDPLGFSLYL FT PENWQRRDFDGDSGELRQIDYTPDGGNHVLRISVDTAPDYNDPYAHQQDLDAQLLQRLV FT DYRRVKLERAGYRDRDSARWEYTWTALAKDTEFPGPRRAVSQMYMSRDGVEYALNMTGP FT AGDWPTTQRRFKAVLQGWQEETG" FT misc_feature 116587..117339 FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 173.70, E-value 3.1e-48" FT misc_feature 116605..116676 FT /note="PS00107 Protein kinases ATP-binding region FT signature" FT misc_feature 116956..116994 FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT CDS 118444..119586 FT /transl_table=11 FT /gene="SCO4778" FT /gene_synonym="pkaI" FT /gene_synonym="SCD63.10" FT /product="serine/threonine protein kinase" FT /note="SCD63.10, pkaI, serine/threonine protein kinase, FT len: 380 aa; similar to TR:CAB50939 (EMBL:AL096849) FT Streptomyces coelicolor putative protein serine/threonine FT kinase SCI11.13, 550 aa; fasta scores: opt: 932 z-score: FT 751.0 E(): 0; 45.0% identity in 416 aa overlap and to FT SW:PKAA_STRCO (EMBL:D86821) Streptomyces coelicolor FT serine/threonine protein kinase PkaA (EC 2.7.1.-), 543 aa; FT fasta scores: opt: 557 z-score: 454.6 E(): 6.8e-18; 33.9% FT identity in 386 aa overlap. Contains Pfam match to entry FT PF00069 pkinase, Eukaryotic protein kinase domain and FT matches to Prosite entries PS00107 Protein kinases FT ATP-binding region signature and possible hydrophobic FT membrane spanning region" FT /db_xref="GOA:Q9L0H9" FT /db_xref="HSSP:1O6Y" FT /db_xref="InterPro:IPR008271" FT /db_xref="UniProtKB/TrEMBL:Q9L0H9" FT /protein_id="CAB82017.1" FT /translation="MGRMVTEGAGGRVIAGRYRLHERLGRGGMGIVWRATDQLLAREVA FT VKALPLDESLSAAEARRRRERTLREARAVAQLRHPHVIVVHDVVEDDGRAYMVMELVDG FT GSLADRVLTRGPVDAVEAARIGVALLDALDTAHASGILHRDVKPSNVLVADDGRVVLTD FT FGVAQVAGATTLTESGSFVGSPEYTAPERMSGAGTGPESDLWSLGVLLCAVLSGASPFH FT RDSLGGVLHAVVTEEIRPPAQAGPLLPVVRGLLERDPRRRLDAASAQRMLRAFLSTGRT FT PATPEEATAARPLRARRSVKRSVLLAVLLVVAAAGAGVSAAALFADGGDDGGGTPTSSV FT PATPTSTPPTSTPPTSTPTTATPTTANPGPPAASGSGNGT" FT misc_feature 118495..119247 FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 214.20, E-value 2e-60" FT misc_feature 118513..118584 FT /note="PS00107 Protein kinases ATP-binding region FT signature" FT misc_feature 118849..119258 FT /note="BlastN hit to EMBL:AB016932 Streptomyces coelicolor FT gene for protein serine/threonine kinase, complete cds." FT misc_feature 118864..118902 FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT repeat_region 119473..119517 FT /note="perfect repeat 3x (PTSTP)" FT CDS 119760..121406 FT /transl_table=11 FT /gene="SCO4779" FT /gene_synonym="pkaJ" FT /gene_synonym="SCD63.11" FT /product="serine/threonine protein kinase" FT /note="SCD63.11, pkaJ, serine/threonine protein kinase, FT len: 548 aa; N-terminal region similar to TR:CAB50939 FT (EMBL:AL096849) Streptomyces coelicolor putative protein FT serine/threonine kinase SCI11.13, 550 aa; fasta scores: FT opt: 1006 z-score: 815.3 E(): 0; 56.9% identity in 297 aa FT overlap and to TR:AAD47061 (EMBL:AF159501) Myxococcus FT xanthus Pkn4, 643 aa; fasta scores: opt: 639 z-score: 521.3 FT E(): 1.4e-21; 43.6% identity in 273 aa overlap and FT C-terminal similar to TR:Q9WTP4 (EMBL:AB019577) Mus FT musculus UNC-51-like kinase (ULK) 2, Ulk2, 1037 aa; blastp FT socres: Sum P(2) = 2.6e-24 Identities = 89/289 (30%), FT Positives = 144/289 (49%). Contains Pfam match to entry FT PF00069 pkinase, Eukaryotic protein kinase domain and FT matches to Prosite entries PS00107 Protein kinases FT ATP-binding region signature and PS00108 Serine/Threonine FT protein kinases active-site signature" FT /db_xref="GOA:Q9L0H8" FT /db_xref="HSSP:1O6Y" FT /db_xref="InterPro:IPR008271" FT /db_xref="UniProtKB/TrEMBL:Q9L0H8" FT /protein_id="CAB86052.1" FT /translation="MPHPGNPYATPTQVVPPRSQTPPSTPAAAPPAAPPATPSSTPAAA FT VPDPGAGRLIAGRYRLIAKLGHGGMGTVWRAKDETVDREVAVKEPRVPDHLPGRERANA FT FERMRREARAAARLDHPAVVDVHDVAVVDDQPWIVMELVRGRSLGDALQEGTLSAREAA FT RIGLEVLGALEAAHAAGVLHRDVKPDNVLLGRHDRVVLTDFGIAQIEGETSLTDTGGFV FT GSPEYIAPERVLGQRPGPASDLWSLGVVLYAATEGVSPFRRSNTPATLQSVLNATPAPP FT ASAQGPLAEVITGLLDKDPARRPDAARVRALLAAAVNPPAPPPTQVVRVDGPEGPGAAP FT ASRWSVRLGRNAWIALGSVVVAAAVASYLVLADPFAGPLPDGWKTPHEKQLAATLAVPE FT NYKRTVPEEAGQHWVTYTDESGAVWIGLTLDKKREDTLGNIAGSAAAEMYDDDGKYKES FT GAYDLAMPENPKTAPRETEYRGGKSAENTVVYTTTDSQNPRPRELRIFYYRTSAGDMYK FT LTVSYPGKGDFTARGREVASTAVANLDIDGT" FT misc_feature 119934..120686 FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 213.00, E-value 4.5e-60" FT misc_feature 119952..120023 FT /note="PS00107 Protein kinases ATP-binding region FT signature" FT misc_feature 120284..120577 FT /note="BlastN hit to EMBL:AB016932 Streptomyces coelicolor FT gene for protein serine/threonine kinase, complete cds." FT misc_feature 120300..120338 FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT CDS 121546..123159 FT /transl_table=11 FT /gene="SCO4780" FT /gene_synonym="SCD63.12" FT /product="putative aldehyde dehydrogenase" FT /note="SCD63.12, probable aldehyde dehydrogenase, len: 537 FT aa; similar to SW:DHAB_BACSU (EMBL:U47861) Bacillus FT subtilis betaine aldehyde dehydrogenase (EC 1.2.1.8) GbsA, FT 490 aa; fasta scores: opt: 950 z-score: 1089.2 E(): 0; FT 37.4% identity in 460 aa overlap. Contains Pfam match to FT entry PF00171 aldedh, Aldehyde dehydrogenase family and FT match to Prosite entry PS00687 Aldehyde dehydrogenases FT glutamic acid active site" FT /db_xref="GOA:Q9L0H7" FT /db_xref="HSSP:1A4S" FT /db_xref="InterPro:IPR016162" FT /db_xref="UniProtKB/TrEMBL:Q9L0H7" FT /protein_id="CAB82019.1" FT /translation="MTDAQAPELTGTNPLAPTPEGARTAADVVTPELVAQLTKGVAGSG FT RTANHTPFTGEKLADLPESTPEDVAGAFERARAAQAVWAQVPVRQRAAVLLRFHDLVLE FT RQAEVLDLIQLETGKARLHAHEEVQAVAVAARHYGRKAPAYLRPKRHTGAVPTLTKVTE FT LRHPRGVVGQIAPWNYPLELSVGDALPAFVAGNAVVMKPDTETCLTALWARDLLIEAGL FT PAEVFQVVLGDGPVVGPEVVRHADYVSFTGSTRTGREVAQGAAARLVGVSLELGGKNAM FT LVLEDADIEKAAAGAVRACFSSAGQLCISIERLYVHASVADAFLERFAARTRAMRLGTS FT LSYGADMGSLVGERQLATVTAHVADAVERGAKLVAGGVARPDIGPYFYEPTILDGVVAP FT MTVCAEETFGPVVSVYRFTTEDEAVEHANSTPYGLNSSVWTKDARRGRDVAARLRTGTV FT NINEGYAPAYGSVQSPMGGMKDSGLGRRHGSEGILKYTEAQTVAHQRLLPMAPSLGMDD FT EKYAAFMSRSLRLMKSLRFR" FT misc_feature 121660..123060 FT /note="Pfam match to entry PF00171 aldedh, Aldehyde FT dehydrogenase family, score 473.50, E-value 1.7e-138" FT misc_feature 122362..122385 FT /note="PS00687 Aldehyde dehydrogenases glutamic acid active FT site" FT RBS 123251..123254 FT CDS 123260..125068 FT /transl_table=11 FT /gene="SCO4781" FT /gene_synonym="SCD63.13" FT /product="putative cholesterol oxidase" FT /note="SCD63.13, possible cholesterol oxidase, len: 602 aa; FT similar to TR:Q59530 (EMBL:U00015) Mycobacterium leprae FT probable cholesterol oxidase precursor (EC 1.1.3.6) ChoD, FT 585 aa; fasta scores: opt: 1114 z-score: 1181.0 E(): 0; FT 60.5% identity in 583 aa overlapand to SW:CHOD_BREST FT (EMBL:D00712) Brevibacterium sterolicum cholesterol oxidase FT precursor (EC 1.1.3.6) ChoD, 552 aa; fasta scores: opt: 228 FT z-score: 244.5 E(): 3.4e-06; 26.9% identity in 576 aa FT overlap" FT /db_xref="GOA:Q9L0H6" FT /db_xref="HSSP:3COX" FT /db_xref="InterPro:IPR017896" FT /db_xref="UniProtKB/TrEMBL:Q9L0H6" FT /protein_id="CAB82020.1" FT /translation="MPQDAYDYDVLVVGSGFGGSVSALRLTEKGYRVGVLEAGRRFTRE FT SLPKNSWDLKNYLWAPKLGMFGIQRIHLLGNVMVLAGAGVGGGSLNYANTLYVPPKPFF FT DDPQWRGITDWHEELTPYYDQARRMLGVRLNPTMTPSDVHLKAAAERMGCGDTFHMAPV FT GVFFGDGEDADGTAKAGPGEQVPDPYFGGAGPDRKACNECGECMTGCRHGAKNTLNENY FT LYLAEKAGAVVHPMTTAVSVTDDSRGGFAVATLPTDRKKRGKRGKQQAGRTFTARRVVL FT AAGTYGTQTLLHRMKAGGQLPRLSDVLGELTRTNSEALVGAQTDDRRYRGATGEPRADF FT TRGVAITSSIHPDANTHIEPVRYGKGSNSMGGLSILQVPYAGQTASGASRVLGFLGHAA FT KHPLLVLRSLSNRKWSERTIIGLVMQSLDNSLTTHLKPAGVGKGLLTARQGHGSPNPKQ FT IKAATDGASALAAEINGFAGSNVGELMGTPLTAHFLGGCPIGASRETGVIDPYHRLYGH FT PGISVVDGAAVSANLGVNPSLTITAQAERAMSYWPNKGESDPRPAQGAGYERVAAVAPR FT SPAVPERAFGALRLPFVEMPTVPPKK" FT CDS complement(125187..125846) FT /transl_table=11 FT /gene="SCO4782" FT /gene_synonym="SCD63.14c" FT /product="putative integral membrane protein" FT /note="SCD63.14c, possible integral membrane protein, len: FT 219 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="InterPro:IPR019931" FT /db_xref="UniProtKB/TrEMBL:Q9L0H5" FT /protein_id="CAB82021.1" FT /translation="MCEDTKVDVDIEGLPGEIAAGSGWHEFSLNVANDSGSTLQNLEYL FT AGASADRDGEKLFESKKVGLQAWNPEDRTWEDLDELGYAVGYIGYTDELAPDYEVAVPM FT RINVRADAPVGAGFTLGATIYGDADGECTGFGDVAYRFRIVAPGTDTDGTRPQEGGKAP FT VTVRKPAAGTPEVTGSLAATGSSSALPVIGLVGGLAVVVGGGAVFVVRRRRAGSDT" FT RBS 125886..125889 FT CDS 125890..126213 FT /transl_table=11 FT /gene="SCO4783" FT /gene_synonym="SCD63.15" FT /product="hypothetical protein SCD63.15" FT /note="SCD63.15, unknown, len: 107 aa" FT /db_xref="UniProtKB/TrEMBL:Q9L0H4" FT /protein_id="CAB82022.1" FT /translation="MLGEGFAGADVVGCVSSGAGVPSPVVLGETGEVGEAEELEDGLVE FT SLGAGEVTLVDPPWDGALSEEADGDGDGPPLAEAAGAASRATGQITAVAAAAARARRSF FT MPV" FT CDS complement(126560..126892) FT /transl_table=11 FT /gene="SCO4784" FT /gene_synonym="SCD63.16c" FT /product="hypothetical protein SCD63.16c" FT /note="SCD63.16c, hypothetical protein, len: 110 aa; FT similar to SW:Y948_MYCTU (EMBL:Z79700) Mycobacterium FT tuberculosis hypothetical 11.8 kD protein RV0984c, FT MTCY10D7.26, 105 aa; fasta scores: opt: 195 z-score: 252.8 FT E(): 1.2e-06; 47.2% identity in 72 aa overlap" FT /db_xref="GOA:Q9L0H3" FT /db_xref="InterPro:IPR010958" FT /db_xref="UniProtKB/TrEMBL:Q9L0H3" FT /protein_id="CAB82023.1" FT /translation="MPVRGAATLRRGATDMTVTAADKTGARTPEAADVITGARERIDAL FT DDRIIGLIQERMAVSAVIQDARITSGGRRVNLSREMEVLDHYREALGKPGTALAMTMLE FT LCRGQV" FT CDS 127216..128796 FT /transl_table=11 FT /gene="SCO4785" FT /gene_synonym="guaA" FT /gene_synonym="SCD63.17" FT /product="GMP synthase" FT /note="SCD63.17, guaA, GMP synthase, len: 526 aa; highly FT similar to SW:GUAA_CORAM (EMBL:Y10499) Corynebacterium FT ammoniagenes GMP synthase [glutamine-hydrolyzing] (EC FT 6.3.5.2) GuaA, 522 aa; fasta scores: opt: 2191 z-score: FT 2442.9 E(): 0; 65.7% identity in 528 aa overlap. Contains FT Pfam matches to entries PF00117 GATase, Glutamine FT amidotransferase class-I and PF00958 GMP_synt_C, GMP FT synthase C terminal domain and match to Prosite entry FT PS00442 Glutamine amidotransferases class-I active site" FT /db_xref="GOA:Q9L0H2" FT /db_xref="HSSP:1GPM" FT /db_xref="InterPro:IPR018318" FT /db_xref="UniProtKB/Swiss-Prot:Q9L0H2" FT /protein_id="CAB82024.1" FT /translation="MSSATPAAAAPDTVLVVDFGAQYAQLIARRVREARVYSEIVPSSM FT PVEEILAKNPAAIILSGGPSSVYEAGAPTLDRSLFEAGVPVFGMCYGFQLMAQTLGGTV FT DNSGAREYGRTELAVSKPSSTLFEGTPAEQSVWMSHGDACSAAPEGFTVTGSTDVVPVA FT AFENDEKKLYGVQYHPEVMHSTHGQQVLEHFLYRGAGLSPDWTTGNVIEEQVAAIRAQV FT GDRRAICGLSGGVDSAVAAALVQKAIGSQLTCVYVDHGLMRKGETEQVEKDFVAATGVQ FT LKVVDASERFLGALAGVSDPEQKRKIIGREFIRVFEQAQLEIMREDGPEVAFLVQGTLY FT PDVVESGGGTGTANIKSHHNVGGLPDDIEFELVEPLRQLFKDEVRMVGQELGLPDEIVQ FT RQPFPGPGLGIRIVGEVTKERLDLLREADAIAREELTAAGLDRDIWQCPVVLLADVRSV FT GVQGDGRTYGHPIVLRPVSSEDAMTADWSRLPYEVLSKISTRITNEVTDVNRVVLDVTS FT KPPGTIEWE" FT misc_feature 127258..127806 FT /note="Pfam match to entry PF00117 GATase, Glutamine FT amidotransferase class-I, score 183.00, E-value 4.7e-51" FT misc_feature 127468..127503 FT /note="PS00442 Glutamine amidotransferases class-I active FT site" FT misc_feature 128482..128793 FT /note="Pfam match to entry PF00958 GMP_synt_C, GMP synthase FT C terminal domain, score 219.90, E-value 3.7e-62" FT CDS complement(128800..129267) FT /transl_table=11 FT /gene="SCO4786" FT /gene_synonym="SCD63.18c" FT /product="hypthetical protein SCD63.18c" FT /note="SCD63.18c, unknown, len: 155 aa" FT /db_xref="GOA:Q9L0H1" FT /db_xref="InterPro:IPR011576" FT /db_xref="UniProtKB/TrEMBL:Q9L0H1" FT /protein_id="CAB82025.1" FT /translation="MNWAGFAAAEPGLAGTVEARFGAYPHHVLATLRKDGSPRTAGLEV FT RFLTGELWLGMMPDSLKALDLRRDPRFALQANPGDGTGMGGGDVRIAGRAVEVEDPRTK FT AGYVREVEPPEPFHLFRTELTEVVRTRVEDDKYLVVEIWQPGRPLRTVRRA" FT CDS 129413..130216 FT /transl_table=11 FT /gene="SCO4787" FT /gene_synonym="SCD63.19" FT /product="putative aldolase" FT /note="SCD63.19, possible aldolase, len: 267 aa; similar to FT SW:ADDA_HUMAN (EMBL:X58141) Homo sapiens erythrocyte FT adducin alpha subunit AddA, 737 aa; fasta scores: opt: 422 FT z-score: 487.2 E(): 1e-19; 35.4% identity in 240 aa overlap FT . Contains Pfam match to entry PF00596 Aldolase_II, Class FT II Aldolase and Adducin N-terminal domain" FT /db_xref="GOA:Q9L0H0" FT /db_xref="InterPro:IPR001303" FT /db_xref="UniProtKB/TrEMBL:Q9L0H0" FT /protein_id="CAB82026.1" FT /translation="MHGTPGAAEPPPLPTDRLRFAMPPRHDSVEDERRHRKERLAGALR FT LFGRQGFEDGVSGHITVRDPQYTDCFWVNPFGVPFAHITVSDLVLVNSEGQVVEGGHHV FT NQAAFTVHSQVHAARPDVVAVAHCHSVHGRALSALGEPLEPITQESCAFYEDHALYDSY FT SGVAVDAEEGRRIAGVLGSGKALVLRNHGLLTVGDSVDAAAWWFLSLERSCQVQLLAKA FT AGRPVPIGHRQAVATREQLGGDLVAWINYQPLWQEVTRREPDLFD" FT misc_feature 129509..130135 FT /note="Pfam match to entry PF00596 Aldolase_II, Class II FT Aldolase and Adducin N-terminal domain., score 85.80, FT E-value 8.9e-22" FT CDS 130378..131673 FT /transl_table=11 FT /gene="SCO4788" FT /gene_synonym="SCD63.20" FT /product="putative ntegral membrane protein" FT /note="SCD63.20, possible integral membrane protein, len: FT 431 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9L0G9" FT /protein_id="CAB82027.1" FT /translation="MAVQEARRGSGSDRDAYEAAHGGGCTCGDCPHGAREGHRRAVAAF FT LLRRDEFAAGQGLPAAVAHSASASRQWVSEELTQSAEAVAERGRAEGDAWLAALGRRTA FT AVVWAAVVLLLLGQSLTAVGTGWSAARTAGLAAALVVAGALTAASWFHRARGGALAPVI FT GEDNRLSTSRAVAAAWVLFVAYAVLVLAGQLAVASGHGRRDALISGLELGRGTGAVTVL FT AVVCGIAVLVRRVVGLRVLGQRLQKVRADRPRASDLLTDDAGRGTFADIQYVVISTVAL FT VFAAVRLARRPEQLPDLPWGLAVVVLVSAATYVAGKYAEGGRPVILSVVRAREAGDLDA FT PIRTGDDIEIRGAGFVPPGAQRADRLSRMVVRIGAVNVHVPLVPVTGGFSNPTDDLLTV FT PVPADVEPGRVDVQVVTGAGVETNRYAIDVTD" FT CDS 131825..132340 FT /transl_table=11 FT /gene="SCO4789" FT /gene_synonym="SCD63.21" FT /product="putative integral membrane protein" FT /note="SCD63.21, possible integral membrane protein, len: FT 171 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="InterPro:IPR011637" FT /db_xref="UniProtKB/TrEMBL:Q9L0G8" FT /protein_id="CAB82028.1" FT /translation="MRTDVHISPGSGGDWRDHAARYALLPLRIFLGVTFVYAGLDKLTD FT SAFMKDSGAGSVGDMMRTVRDSSAVPALVDLALKNPPGFGYAIALGELAVGIGTLLGLL FT TRLAALGGALISLSLWLTVSWASDPYYYGNDLAYLMAWLPLVLAGAPLLSLDALLRSRH FT RRRTGGYR" FT CDS complement(132551..133972) FT /transl_table=11 FT /gene="SCO4790" FT /gene_synonym="SCD63A.01c" FT /gene_synonym="SCD63.22c" FT /product="putative integral membrane protein" FT /note="SCD63A.01c, possible integral membrane protein FT (fragment), len: >35 aa" FT /note="SCD63.22c, possible integral membrane protein FT (fragment), len: 171 aa. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="InterPro:IPR007168" FT /db_xref="UniProtKB/TrEMBL:Q8CJS9" FT /protein_id="CAD55215.1" FT /translation="MTDHEHAATGPGPGSGPRPPQGAGPQDAAPAADAGAAGPGAAGGT FT DAAGPTHRFRRDRRHKSLAGVCAGLGRQCDMDPVIFRITLAVLSATGGIGLIFYGFAWL FT FVPYEDEEENEVRKLLTGRVDGHALAAVLFALVGCGVFLTMLRNGGVLTFAVVLSLLLA FT GAGYWSRHRRAPEPDPLSAQAVADAPPEAKAPPIMYTWPSWWRDPIVKDGTHDGGTGYM FT WGPPDSAERDIAAAVNIGRGIPGRRDRATAGDRHSWSAQTRGPRGIGGWVFLLALLAGF FT LGARLTWDDHPLGTSLQTGLACALAVFGLGIAVSSFLGRTGAGSIFLAVITAGLLAGSA FT AVPENVGTDWVRTTWKPVVAADVRDQYDLGTGSGTLDLSRLDLAEGQTVTTRADVGMGR FT IRVVVPPDVTVRLYVEVGVGDIQLPGDNKKDVDVAPGKHKEITLPPAEGGKSSGTLDLD FT LQVGVGQAEVSRAAS" FT CDS 134163..135455 FT /transl_table=11 FT /gene="SCO4791" FT /gene_synonym="SCD63A.02" FT /product="putative two-component system sensor kinase" FT /note="SCD63A.02, possible two-component system sensor FT kinase, len: 430 aa; C-terminal domain similar to FT TR:CAB51969 (EMBL:AL109661) Streptomyces coelicolor FT putative two-component system sensor kinase SC6E10.15c, 413 FT aa; fasta scores: opt: 168 z-score: 198.3 E(): 0.0014; FT 32.7% identity in 248 aa overlap. Contains possible FT hydrophobic membrane regions in N-terminal domain" FT /db_xref="GOA:Q9KY73" FT /db_xref="InterPro:IPR007168" FT /db_xref="UniProtKB/TrEMBL:Q9KY73" FT /protein_id="CAB92654.1" FT /translation="MPEAAAAPVVEPRPPRKLYRSSDGRWLGGVARGLAGHLGLPVVWV FT RFAFVGLFMADGLGALLYAAFWFFVPLGVGGVEAQKPPSLVTSETGPDGRRRLVTRKPD FT KGQIVALLLMVVVALVFVGNVDLGGGAKAYLWPTVLVGAGVALVWRQADNARRARWAEV FT GRHRRTVTLLRSVGGVLLVTAGVTGIFVLQGSAAHLGSVLQAALAVLVGITLLAGPYLV FT RMTQDLSEERLMRIRAQERAEVAAHVHDSVLHTLTLIQRNAENAGEVRRLARAQERDLR FT SWLYKPEGNGKDEDDEPTTLAEAVKRNAAEVEDKHGVPLEVVVVGDCPLDERISAQMQA FT AREAMVNAAKYGGEGGAVQVYAEVEGRTVFVSVRDRGPGFDFDSIPADRMGVRESIIGR FT MERNGGTARLRAVPDGGTEVELEMERAEKTS" FT RBS 135440..135444 FT CDS 135452..136207 FT /transl_table=11 FT /gene="SCO4792" FT /gene_synonym="SCD63A.03" FT /product="putative two-component system DNA-binding FT response regulator" FT /note="SCD63A.03, probable two-component system DNA-binding FT response regulator, len: 251 aa; similar to SW:NARL_ECOLI FT (EMBL:X13360) Escherichia coli nitrate/nitrite response FT regulator protein NarL, 216 aa; fasta scores: opt: 428 FT z-score: 490.1 E(): 7.8e-20; 34.1% identity in 214 aa FT overlap and to TR:CAB51968 (EMBL:AL109661) Streptomyces FT coelicolor putative two-component system regulator FT SC6E10.14c, 215 aa; fasta scores: opt: 517 z-score: 472.3 FT E(): 9.4e-21; 44.3% identity in 219 aa overlap. Contains FT Pfam matches to entries PF00072 response_reg, Response FT regulator receiver domain and PF00196 GerE, Bacterial FT regulatory proteins, luxR family and match to Prosite entry FT PS00622 Bacterial regulatory proteins, luxR family FT signature. Contains also possible helix-turn-helix motif at FT residues 206..227 (+2.85 SD)" FT /db_xref="GOA:Q9KY72" FT /db_xref="HSSP:1FSE" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9KY72" FT /protein_id="CAB92655.1" FT /translation="MSDPTEANGTAGTAGAGEAARPAQPAGDGAGERRVRVVLVDDHRM FT FRTGVQAEIGQTAETGVEVVGEAADVDQAVTVITATRPEVVLLDVHLPGGGGVEVLRRC FT APLMSDAERPVRFLALSVSDAAEDVIGVIRGGARGYVTKTITGTDLVDSVFRVQEGDAV FT FSPRLAGFVLDAFASTDAPPVDEDLDRLTQREREVLRLIARGYAYKEIAKQLYISVKTV FT ESHVSAVLRKLQLSNRHELTRWATARRLV" FT misc_feature 135554..135913 FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 55.50, E-value 1.2e-12" FT misc_feature 136013..136204 FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 73.60, E-value FT 4.2e-18" FT misc_feature 136064..136147 FT /note="PS00622 Bacterial regulatory proteins, luxR family FT signature" FT CDS complement(136309..137352) FT /transl_table=11 FT /gene="SCO4793" FT /gene_synonym="SCD63A.04c" FT /product="putative NPL/P60 family secreted protein" FT /note="SCD63A.04c, probable NPL/P60 family secreted FT protein, len: 347 aa; similar to TR:Q9XAQ3 (EMBL:AL078618) FT Streptomyces coelicolor SCD16A.22, 277 aa; fasta scores: FT opt: 409 z-score: 418.8 E(): 7.3e-16; 34.8% identity in 250 FT aa overlap, to TR:Q9X7Z5 (EMBL:AL049497) Streptomyces FT coelicolor putative secreted protein SC6G10.09c, 347 aa; FT fasta scores: opt: 928 z-score: 800.9 E(): 0; 44.2% FT identity in 353 aa overlap and to Streptomyces coelicolor FT SCD63A.07c, 398 aa. Contains Pfam match to entry PF00877 FT NLPC_P60, NLP/P60 family and possible N-terminal region FT signal peptide sequence. Contains also possible colied-coil FT region at aprox. residues 58..98" FT /db_xref="InterPro:IPR000064" FT /db_xref="UniProtKB/TrEMBL:Q9KY71" FT /protein_id="CAB92656.1" FT /translation="MGTHRRPRQRAKGGGRARTAATITLAGAATATGLGGTTVHADPQP FT TAAQVRAKVDKLYQEAEVATEKYNGAKEKADAAERRLEDLRDEAARKEDRLNSAREALG FT SVAAAQYRSGGLDPALQLALSSDPDRYLDGAAFAERAGSRRQAEVGRVRKELRDIEQLR FT GAARVEAASLRSRRAELKRHRETVIGKLEKARRLLSRLTTEERADVGDRASRSAPGPRE FT GLTPSSQAPDSRAAAAVAYAYQKLGSPYVWGATGPNAFDCSGLTQAAYRAAGVSLPRTT FT YAQIDAGRRVSRSELLPGDLVFFYSGISHVGIYVGNGRMIHAPNPSAPVRVAPVDEMPF FT AGATRVA" FT misc_feature complement(136315..136629) FT /note="Pfam match to entry PF00877 NLPC_P60, NLP/P60 FT family, score 152.50, E-value 7.2e-42" FT CDS 137478..138014 FT /transl_table=11 FT /gene="SCO4794" FT /gene_synonym="SCD63A.05" FT /product="putative integral membrane protein" FT /note="SCD63A.05, possible integral membrane protein, len: FT 178 aa. Contains possible hydrophobic membrane spanning FT regions and a TTA leucine codon (codon 57), possible target FT for bldA regulation" FT /db_xref="UniProtKB/TrEMBL:Q9KY70" FT /protein_id="CAB92657.1" FT /translation="MAAADRAATASDRYALRGPASSRRVMTVMPDRGRVGDVSCYGSAG FT AGRCPGASGPSLGSGLMDVLIHLFVGLHIIGIASLLGGFLTQMKAMGQGAARFTPAMLH FT GALTMLVTGAVLVGLNQAQDYSVDNVKIGVKLAVLIVILGLVYVKRDEEKVEKPLFGLV FT GALTLANIFIAVLWT" FT misc_feature 137646..137648 FT /gene="none" FT /note="TTA leucine codon. Possible target for bldA FT regulation" FT CDS complement(137992..139008) FT /transl_table=11 FT /gene="SCO4795" FT /gene_synonym="SCD63A.06c" FT /product="putative integral membrane protein" FT /note="SCD63A.06c, possible integral membrane protein, len: FT 338 aa; similar to TR:O88074 (EMBL:AL031541) Streptomyces FT coelicolor putative integral membrane protein SCI35.39,394 FT aa; fasta scores: opt: 142 z-score: 173.6 E(): 0.033; 28.0% FT identity in 311 aa overlap. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q9KY69" FT /db_xref="InterPro:IPR004695" FT /db_xref="UniProtKB/TrEMBL:Q9KY69" FT /protein_id="CAB92658.1" FT /translation="MSSATHPSALRTWWAQRPPAAGAAVMATGIVSVALHLTGREVLSR FT ITLALACAAWLILAANFVYLLLADHAQWVKRAGTPGALTAVAATTVLGTRFSLLGWTLL FT AAVLLALASLLWPWLLFLVVQHWGRRMPGAVFLGCVATEGLTVLAATLAAATSTPWLAH FT VALVPFWLGIVLYLIALFRFDLRQVARGSGDHWVAGGALAISALAGAKLLAAAGTGMYL FT WNADDQAVLHDVTVLLLTLDLAWYAVLLAAEIAWPRLRYDVRRWSTVFPLGMTAAATLS FT VAAVLDVPWLDAPGRALLWIAVAGWLAVATGAVLRARSGLRSADADPGPAVRSTAPR" FT CDS complement(139035..140231) FT /transl_table=11 FT /gene="SCO4796" FT /gene_synonym="SCD63A.07c" FT /product="putative NLP/P60 family secreted protein" FT /note="SCD63A.07c, possible NLP/P60 family secreted FT protein, len: 398 aa; similar to TR:Q9XAQ3 (EMBL:AL078618) FT Streptomyces coelicolor putative NLP/P60 family secreted FT protein SCD16A.22, 277 aa; fasta scores: opt: 479 z-score: FT 430.6 E(): 1.6e-16; 39.1% identity in 233 aa overlap, to FT TR:Q9X7Z5 (EMBL:AL049497) Streptomyces coelicolor putative FT secreted protein SC6G10.09c, 347 aa; fasta scores: opt: 576 FT z-score: 513.3 E(): 4e-21; 41.5% identity in 395 aa overlap FT and to Streptomyces coelicolor SCD63A.04c, 347 aa. Contains FT Pfam match to entry PF00877 NLPC_P60, NLP/P60 family. FT Contains also possible coiled-coil regions at aprox. FT residues 58..98 and 176..242 and possible N-terminal signal FT peptide sequence" FT /db_xref="InterPro:IPR000064" FT /db_xref="UniProtKB/TrEMBL:Q9KY68" FT /protein_id="CAB92659.1" FT /translation="MASHRKSRPTGPRVAGIRTPALATAALTSVALLSQTANATPSDDR FT PTLEEVEKKVDDLYRQAGSATEKYNAAKEKTTKQRKKVDTLLDDVAQRTQKLNDAREEL FT GSFASAQYRTGASVPETATLLLADSPQDYFDQNQLMNRLTGRQKTAVDDYVTQQSETMK FT KRREATESLETLTDSQTDLKSAKSTVQKKLATARELLSELTAEEKARLAAIERKKQEEA FT ERKAAELAKQQAAQEDAERKRREEAAQQQESGSGSSGTSGGTGSSDSSGSSTPGTSTGT FT KAEKAIAFARAQIGKPYVWGATGPGSYDCSGLTQAAWKAAGVTLPRVTYDQVNAGTTVS FT VSQAQPGDLVFFYDDISHVGLYIGDGMMIHAPKPGAYVREESIFYDGESSIYSVVRPA" FT misc_feature complement(139044..139364) FT /note="Pfam match to entry PF00877 NLPC_P60, NLP/P60 FT family, score 125.10, E-value 1.3e-33" FT RBS complement(140240..140243) FT RBS 140666..140670 FT CDS 140674..143169 FT /transl_table=11 FT /gene="SCO4797" FT /gene_synonym="SCD63A.08" FT /product="putative ATP-dependent DNA helicase II" FT /note="SCD63A.08, probable ATP-dependent DNA helicase II, FT len: 831 aa; similar to TR:P73465 (EMBL:D90906) FT Synechocystis sp. DNA helicase II UvrD, 793 aa; fasta FT scores: opt: 1417 z-score: 1459.4 E(): 0; 40.4% identity in FT 817 aa overlap and to SW:REP_ECOLI (EMBL:M87049) FT Escherichia coli ATP-dependent DNA helicase Rep, 673 aa; FT fasta scores: opt: 824 z-score: 849.5 E(): 0; 37.8% FT identity in 661 aa overlap. Contains Pfam match to entry FT PF00580 UvrD-helicase, UvrD/REP helicase and match to FT Prosite entry PS00017 ATP/GTP-binding site motif A FT (P-loop)" FT /db_xref="GOA:Q9KY67" FT /db_xref="HSSP:1PJR" FT /db_xref="InterPro:IPR014017" FT /db_xref="UniProtKB/TrEMBL:Q9KY67" FT /protein_id="CAB92660.1" FT /translation="MSSLFDDSFLASLQTPRGHEEEPPPPPEDDHGPEPVPHDLFGGKF FT DAPPQRDTHYRDGAPRPALDAAALLEGLNENQRAAVVHSGSPLLIVAGAGSGKTRVLTH FT RIAHLLAERNVHPGQILAITFTNKAAGEMKERVEQLVGPRANAMWVMTFHSACVRILRR FT ESKKLGFTSSFSIYDAADSKRLMALVCRDLDLDPKRFPPKSFSAKISNLKNELIDEEDF FT AAQAADGFEKTLAQAYAMYQSRLREANALDFDDLIMTTVNLLRAFPDVAEHYRRRFRHV FT LVDEYQDTNHAQYALVRELVGVPSEHPVDVPPEAEVPPAELCVVGDADQSIYAFRGATI FT RNILQFEEDYPDATTILLEQNYRSTQTILSAANAVIERNESRRPKNLWTNQGSGAQITG FT YVADTEHDEAQFVADEIDRLTDAGEAKAGDVAVFYRTNAQSRVFEEVFIRTGLPYKVVG FT GVRFYERKEVRDVLAYLRVLANPEDSVPLRRILNVPKRGIGDRAEAMIDALSQREKISF FT PQALRRVDEAYGMAARSANAVKRFNTLMEDLRTIVESGAGPATVLEAILERTGYLAELQ FT ASTDPQDETRIENLQELAAVALEFEQERAEGEEAGTLADFLEKVALVADSDQIPDEEDG FT DGVVTLMTLHTAKGLEFPVVFLTGMEDGVFPHMRALGQAKELEEERRLAYVGITRARER FT LYLTRSTLRSAWGQPSYNPPSRFLEEIPAPHLEWKRTGANGPAPSAPVSGVAASLSSSR FT SRSRSSASGASGFATGRSAGAEQPTVSLAVGDRVTHDQFGLGTVVGVKGSGSNAEATID FT FGDTKPKRLLLRYAPVEKL" FT misc_feature 140893..142359 FT /note="Pfam match to entry PF00580 UvrD-helicase, UvrD/REP FT helicase, score 464.60, E-value 8e-136" FT misc_feature 140947..140970 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(143259..144956) FT /transl_table=11 FT /gene="SCO4798" FT /gene_synonym="SCD63A.09c" FT /product="putative peptidase" FT /note="SCD63A.09c, possible peptidase, len: 565 aa; FT C-terminal region similar to SW:LSTP_STAST (EMBL:X06121) FT Staphylococcus staphylolyticus lysostaphin precursor (EC FT 3.4.24.75) Lss, 480 aa; fasta scores: opt: 299 z-score: FT 293.2 E(): 7.2e-09; 25.0% identity in 368 aa overlap and to FT TR:O50513 (EMBL:AL009204) Streptomyces coelicolor FT hypothetical protein SC9B10.06, 250 aa; fasta scores: opt: FT 458 z-score: 352.7 E(): 4.3e-14; 41.6% identity in 231 aa FT overlap. Contains Pfam match to entry PF01551 FT Peptidase_M37, Peptidase family M23/M37" FT /db_xref="GOA:Q9KY66" FT /db_xref="InterPro:IPR002886" FT /db_xref="UniProtKB/TrEMBL:Q9KY66" FT /protein_id="CAB92661.1" FT /translation="MNDRHPSGTRTAPASASDAASAPYASYGTGEAQYGNLTTYGGGHA FT SAGFATGGADSSAFDADPLFGSMPGHYAGSPEATGSYDTTQWSTGGEQSPHYDAYAAQH FT HAAYDTGAYDTTTWTAGYQQPGSVSPQATGAEGTGQWDTGAWAGADHCAAPADATQQWD FT WGTQTCETGTFDTGAFEPGTTDTGAFDTRAFDTGAFPAGAFETSAFTTGTFHTGAFAGG FT PVDTGAYDATQWNPDAGATGTAEDPDRPAGHPVPDDVTPDAAPLTEGTEPSPYGEELAA FT TGELPAVTALLDDQEEATPDARIPVARAGSRAGARSRRRQPAKRSALLTIAVPSACVMS FT VAGIAAASVGSLTGDEGTETAASAPDPGNAEAAPVKPSAANNKLDTQLTSLAAGADDFA FT DRASRTQERIDLKAEQDAEKKRAAQEAARKERLRPKFALPVKQHGLSAYYGQAGINWMS FT SHTGIDFPVLQGTTVMAATDGTVRTQFNSAYGNMMIVTAKDGTETWYCHLSSYQVPSGT FT TVKAGDAIAYSGDSGNSTGPHLHFEVRPAGGSSIDPLPWLRSHGLNPT" FT misc_feature complement(143289..143537) FT /note="Pfam match to entry PF01551 Peptidase_M37, Peptidase FT family M23/M37, score 115.00, E-value 1.5e-30" FT CDS complement(145153..146148) FT /transl_table=11 FT /gene="SCO4799" FT /gene_synonym="SCD63A.10c" FT /product="putative secreted lipase" FT /note="SCD63A.10c, possible secreted lipase, len: 331 aa; FT similar to SW:LIP_BACSU (EMBL:M74010) Bacillus subtilis FT lipase precursor (EC 3.1.1.3) LipA, 212 aa; fasta scores: FT opt: 188 z-score: 190.5 E(): 0.0038; 26.5% identity in 211 FT aa overlap and to TR:AAF11628 (EMBL:AE002044) Deinococcus FT radiodurans lipase, putative, 237 aa; fasta scores: opt: FT 309 z-score: 302.6 E(): 2.2e-09; 32.0% identity in 200 aa FT overlap. Contains match to Prosite entry PS00120 Lipases, FT serine active site and possible N-terminal region signal FT peptide sequence" FT /db_xref="GOA:Q9KY65" FT /db_xref="InterPro:IPR003386" FT /db_xref="UniProtKB/TrEMBL:Q9KY65" FT /protein_id="CAB92662.1" FT /translation="MKVTTAALPLLPLFQRLLPGLPGLPGLQRLPSVPGLSAVPGLPEL FT ASLPGRLTGLSLTLLKASALEAAILAGHLLLYPSGIIQERHPAQTLRPQGAQDPLPSPP FT PPRLPAPASPPVVLLHGFIDNRSVFLLLRRSLAQHGRHAIESLNYSPLTCDIRTAAELL FT GRHIEEICERTGSERVDVVGHSLGGLIARYYVQRLGGDLRVRTLVTLGTPHTGTKVVPL FT ANAHPIVRQMRPGSAVIEELTRPAPGCRTRFVSFWSDLDRVMDPLETACLDHPDLSVQN FT VRVSGIGHLALPVHPAVATGIRQALDTAGPETAGQTDAEPGKRSGGLTVA" FT misc_feature complement(145585..145614) FT /note="PS00120 Lipases, serine active site" FT RBS complement(146156..146161) FT RBS 146533..146536 FT CDS 146542..146958 FT /transl_table=11 FT /gene="SCO4800" FT /gene_synonym="icmB" FT /gene_synonym="SCD63A.11" FT /product="isobutiryl CoA mutase, small subunit" FT /note="SCD63A.11, icmB, isobutyryl CoA mutase, small FT subunit, len: 138 aa; almost identical to TR:CAB59633 FT (EMBL:AJ246005) Streptomyces cinnamonensis isobutyryl CoA FT mutase, small subunit (EC 5.4.99.13) IcmB, 136 aa; fasta FT scores: opt: 803 z-score: 972.5 E(): 0; 92.5% identity in FT 134 aa overlap and highly similar to TR:CAB71846 FT (EMBL:138667) Streptomyces coelicolor probable FT isobutyryl-CoA mutase, small subunit SC3D9.01, 159 aa; FT fasta scores: opt: 594 z-score: 628.1 E(): 2e-29; 70.6% FT identity in 126 aa overlap" FT /db_xref="GOA:Q9KY64" FT /db_xref="HSSP:1REQ" FT /db_xref="InterPro:IPR006159" FT /db_xref="UniProtKB/TrEMBL:Q9KY64" FT /protein_id="CAB92663.1" FT /translation="MGVAAGPIRVVVAKPGLDGHDRGAKVIARALRDAGMEVIYTGLHQ FT TPEQIVDTAIQEDADAIGLSILSGAHNTLFAAVIELLRERDAADILVFGGGIIPEADIA FT PLKEKGVAEIFTPGATTASIVDWVRANVREPAGA" FT CDS complement(147056..148876) FT /transl_table=11 FT /gene="SCO4801" FT /gene_synonym="SCD63A.12c" FT /product="hypothetical protein SCD63A.12c" FT /note="SCD63A.12c, unknown, len: 606 aa. High content in FT alanine amino acid residues" FT /db_xref="UniProtKB/TrEMBL:Q9KY63" FT /protein_id="CAB92664.1" FT /translation="MTRTPAPTDPSAPAPATVSGPAAEPGFSPPDGAPTHPTVPGSDTG FT PPIDAEPDATVAARAAAATGPHPEIGPGTGPGPGVWEGLVTSALLGTDRRPPPGGERGP FT GAAAALLDAAAAETVRRRAGLRPARAARRPEPAPEDPRPPLPPAAARRLTALLADRPGA FT AGGGRRGSAPDLMELLPQWLATANARGFAAPPQALPALLDAARGRTDLRPAALTFAGPR FT ALWLARLNPDWRFALRATPGGGTALPGSDATERVRGLWHEGLFAERVTLLASLRARDPA FT GARELLASTWATERAEDRLMFLDSLRTGLEAADEPFLEQALADRSRNVRATAAELLSAL FT PHSALAARMAARAATCVSLDRTLAPPAIAVEAPHECDAGMERDGVVAKPPAGRGERSWW FT FGQLVEAAPLSTWPTRLAGRTAEEIVALPVSDGWRNELHAAWCRAAVRQRDGGWARALL FT GAPTAPEAGGPGAVSLAERAKLLGTLGAGERAEWVAGFIATHGMSEAFQLLGMCGVPWA FT TPLGRAVVDALNIARDAGSYPWSFSGVMGLAERCLDPSEAGRLDGLLAIPDEPEDASPG FT AGGYWAEAFQRLVTTLRLRAAMAAELGAGS" FT RBS complement(148886..148889) FT CDS complement(148912..150051) FT /transl_table=11 FT /gene="SCO4802" FT /gene_synonym="SCD63A.13c" FT /product="hypothetical protein SCD63A.13c" FT /note="SCD63A.13c, unknown, len: 379 aa" FT /db_xref="UniProtKB/TrEMBL:Q9KY62" FT /protein_id="CAB92665.1" FT /translation="MIAHRSLSVGGPTFDGMARHGVRRGGEPGRGGDVGTAVRGPGGEG FT GRGCAEEGTAGPSAPAAASDPEAARRRAERRAERVTAGATELEQRLADLLRTGLAGAEQ FT AGYGLWEETAARMVDAQAPGLASRVRELAAIPSSGPGWPVRLLEECALLHLLDRGWLGR FT ERLPDGLAATVRSRVGLPTSADGPPVRDHWLVLAQYDTADARLTTRRVWLYGAESDRTA FT LLLSYGAAGRAPELTLPVGAELDAEISAYPGPGRQRAALGRRFAPPEPARTRPPGVTTS FT QAAVRYGAALRDDPWLDSVPVALERVVPVPDGDGWQLADADGDTALPLAWAGGNHPGLW FT RLVALAGGAPVTVFGECGHRGFTPLTAWPAGPGPAVPLC" FT RBS 150120..150123 FT CDS 150135..151256 FT /transl_table=11 FT /gene="SCO4803" FT /gene_synonym="SCD63A.14" FT /product="conserved hypothetical protein" FT /note="SCD63A.14, conserved hypothetical protein, len: 373 FT aa; similar to TR:CAB61595 (EMBL:AL133210) Streptomyces FT coelicolor hypothetical 41.5 kD protein SCG11A.14, 389 aa; FT fasta scores: opt: 774 z-score: 864.5 E(): 0; 46.5% FT identity in 376 aa overlap and to SW:YEHL_ECOLI FT (EMBL:U00007) Escherichia coli hypothetical 42.4 kD protein FT in MolR-BglX intergenic region YehL, 384 aa; fasta scores: FT opt: 771 z-score: 861.2 E(): 0; 41.2% identity in 359 aa FT overlap" FT /db_xref="GOA:Q9KY61" FT /db_xref="InterPro:IPR011704" FT /db_xref="UniProtKB/TrEMBL:Q9KY61" FT /protein_id="CAB92666.1" FT /translation="MPAFVERTPSAEVPRQVLRPHAEHAFAAELASLAGQDDRPRPARW FT RLSPWAVATYLLGGTLPDGTVITPKYVGPRRVVEVAVTTLATDRALLLLGVPGTAKTWV FT SEHLAAAVSGDSTLLVQGTAGTPEEAIRYGWNYARLLAHGPGRDALVPSPVMRAMTEGA FT TVRVEELTRIPADVQDSLITLLSEKTLPIPELGEEVQAVRGFNLIATANDRDRGVNDLS FT SALRRRFNTVVLPLPESAEAEVDIVTRRVDQIGRSLDLPSAPDGTDEIRRVVTVFRELR FT DGLTSDGRTKVKSPSGPLSTAEAISVVTGGLALCAHFGDGVLRAGDLAAGVLGAVVRDP FT GTDRVVWQEYLETVVREREGWQDFYRACREVTA" FT RBS 151347..151350 FT CDS 151359..153806 FT /transl_table=11 FT /gene="SCO4804" FT /gene_synonym="SCD63A.15" FT /product="conserved hypothetical protein SCD63A.15" FT /note="SCD63A.15, hypothetical protein, len: 815 aa; FT similar to TR:CAB61596 (EMBL:AL133210) Streptomyces FT coelicolor hypothetical 135.7 kD protein SCG11A.15, 1320 FT aa; fasta scores: opt: 340 z-score: 332.5 E(): 4.6e-11; FT 30.4% identity in 883 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9KY60" FT /protein_id="CAB92667.1" FT /translation="MTGTDRAGGGGPGGQGGAGEPGGRPLLLGVRHHGPGSARAVRAAL FT EATRPGVVLIEGPPEADALIPLAADEDMRPPVALLAHAVDEPGRSAFWPLAEFSPEWVA FT VRWALEHDVPARFIDLPAAHTLAWRAADGHGDVDADARGDDQAPPGRPGTAPADVRRDP FT LAALAAAAGHDDPERWWEDVIEHRGRGAGDALAPFTALEEAMTALRETEEDGEAEGGED FT REGGDGDVRDLVREAHMRLQVRAARREFAEGVAVVCGAWHVPALRRRATVAADRALLKG FT LPRTKVDMTWVPWTHRRLSRAGGYGAGIESPGWYGHLFAAVDRPVERWLTKVAGLLRAE FT DRIVSPAHVIEATRLAETLAVIRGRPLPGLTEATDAVRAVMCDGSDVPLALVHDRLVVG FT DVLGEVPAGAPAVPLQRDLTRAQRRLRLRPEAPVRELELDLRKETDAGRSRLLHRLRLL FT GVGWGEAVASRSTGTFREAWRLRWEPELSVRVAEAGVWGTTVLSAATARAQADAVTARG FT LAEVTALAERCLLAELPDALAPVMRILADRAALDTDVGHLAQALPALVRSLRYGDVRGT FT DTRALAEVAEGLAERVFVGLPAACAALDADAAEEMRRHVDAVHTAVGLLGDAPAPGRGD FT LHSRWRAVLHTLSARDTVPGVVRGRAVRLLLDDGELAPAEAARLMGLVLSPATPPADAA FT AWIEGFVGGGSGGGMLLLHDERLLALVDAWLTGVPADAFTHVLPLLRRTFSAYEPGVRR FT GLGELVRRGPEARGSVTTAGSGVPGFAAGLDPVRADAVLPVVRLLLGRHPAPDGGDLAG FT ANT" FT repeat_region 153867..153947 FT /note="7x degenerate repeat: CGG(A/G)GCCCA(C/T)G(A/G)" FT CDS 153977..155131 FT /transl_table=11 FT /gene="SCO4805" FT /gene_synonym="SCD63A.16" FT /product="hypothetical protein SCD63A.16" FT /note="SCD63A.16, hypothetical protein, len: 348 aa; FT similar to SW:YEHP_ECOLI (EMBL:) Escherichia coli FT hypothetical 42.1 kD protein in MolR-BglX intergenic region FT YehP, 378 aa; fasta scores: opt: 721 z-score: 816.7 E(): 0; FT 35.7% identity in 378 aa overlap" FT /db_xref="InterPro:IPR002035" FT /db_xref="UniProtKB/TrEMBL:Q9KY59" FT /protein_id="CAB92668.1" FT /translation="MDAEAARERLRRWRLVLGGDPADGTGHVLCGRDAAMDGALTALYG FT RGGAPRAGRDRAAGLGASAPAVARWLGDIRTYFPSPVVQVMQRDAIDRLGLATLLLEPE FT MLQAVEADVHLVGTLLSLNEAMPDTTRETARAVVRKVVEDLEKRLVTRTRATLSGALDR FT SARTARPRPHDIDWNRTIGANLKHYLPEYRTVVPERLVGYGRASRSVRKDIVLCVDQSG FT SMAASLVYASVFGAVLASMRSIDTRLVVFDTAVADLTDQLDDPVDVLFGTRLGGGTDIN FT RALAYCQSRITRPADTVVVLISDLYEGGIREEMLKRVAAMRVAGVRFVTLLALSDEGTP FT AYDREHAAALAALGAPAFACTPDLFPEVMAAAIEGRPLPIPDAG" FT CDS 155302..156246 FT /transl_table=11 FT /gene="SCO4806" FT /gene_synonym="SCD63A.17" FT /product="putative secreted protein" FT /note="SCD63A.17, possible secreted protein, len: 314 aa. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="UniProtKB/TrEMBL:Q9KY58" FT /protein_id="CAB92669.1" FT /translation="MIWSAVLPGAALRVLRTAAGRRALHVALLAGGLFLLGLLCGGRAQ FT AADGATESSKDTVGQVLDIPARTDERPGAVLPDLRPVSEKVVRAVRDRVARPVGAAVRT FT VTEGVEGAEADLRTDVPPLRVLPDLTGLSDLSDLTDPSGPSDPSAPRDGVPGLTDVPDL FT TDGSGGSSSSAASAVPEPRAEPAPPVAGASGGEASSDTTDSRAVDGAASPVRVVGYGPE FT PGAGAALTARARTHPAGTAYTEYAPARPAPTGDPDGALGTASGADQGTSRHGDTRAVTS FT PHRITFRLVPGAPERTDAAGVREPHRDVPVSPA" FT CDS 156378..156833 FT /transl_table=11 FT /gene="SCO4807" FT /gene_synonym="SCD63A.18" FT /product="hypothetical protein SCD63A.18" FT /note="SCD63A.18, unknown, len: 151 aa. Doubtful CDS" FT /db_xref="UniProtKB/TrEMBL:Q9KY57" FT /protein_id="CAB92670.1" FT /translation="MPLAVRTSRSGHPPRPPAPDTAFRAPRSERTRDGSRGSAPAGRLP FT RDGAEAGRSGPGTGTSWPRRAAGTDPAGRQAPDGRKPSASVRPKPRGPVRRVPIGVGTS FT RTAPRRTASVRPAGSPRASPGQPQPGEALHPICGAPRVHLTHGTACQ" FT CDS 157043..158227 FT /transl_table=11 FT /gene="SCO4808" FT /gene_synonym="sucC" FT /gene_synonym="SCD63A.19" FT /product="succinyl-CoA synthetase beta chain" FT /note="SCD63A.19, sucC, succinyl-CoA synthetase beta chain, FT len: 394 aa; similar to SW:SUCC_ECOLI (EMBL:J01619) FT Escherichia coli succinyl-CoA synthetase beta chain (EC FT 6.2.1.5) SucC, 388 aa; fasta scores: opt: 873 z-score: FT 928.1 E(): 0; 40.6% identity in 394 aa overlap and to FT TR:O87840 (EMBL:AL031013) Streptomyces coelicolor FT succinyl-coa synthetase beta chain SucC1 SC8A6.06, 383 aa; FT fasta scores: opt: 983 z-score: 992.7 E(): 0; 60.3% FT identity in 393 aa overlap. Contains Pfam match to entry FT PF00549 ligase-CoA, CoA-ligases and match to Prosite entry FT PS01217 ATP-citrate lyase / succinyl-CoA ligases family FT signature 3" FT /db_xref="GOA:Q9KY56" FT /db_xref="HSSP:1JKJ" FT /db_xref="InterPro:IPR016102" FT /db_xref="UniProtKB/Swiss-Prot:Q9KY56" FT /protein_id="CAB92671.1" FT /translation="MDLFEYQARDLFAKHDVPVLAGEVIDTPEAAREITERLGGKSVVK FT AQVKVGGRGKAGGVKLAASADEAVARATDILGMDIKGHTVHKVMIAETAPEIVEEYYVS FT FLLDRANRTFLSIASVEGGVEIEEVAATRPEAVAKTPIDAIDGVTPEKAREIVEAAKFP FT AEVADKVADILVKLWDTFIKEDALLVEVNPLAKVVSGDVIALDGKVSLDDNAEFRHPDF FT EALHDKAAANPLEAAAKEKNLNYVKLDGEVGIIGNGAGLVMSTLDVVAYAGEAHGNVKP FT ANFLDIGGGASAQVMANGLEIILGDPDVRSVFVNVFGGITACDEVANGIVQALKLLEDR FT GEKVEKPLVVRLDGNNAELGRKILTDANHPLVQRVDTMDGAADKAAELAHAAAK" FT misc_feature 157757..158143 FT /note="Pfam match to entry PF00549 ligase-CoA, CoA-ligases, FT score 127.20, E-value 2.2e-34" FT misc_feature 157790..157864 FT /note="PS01217 ATP-citrate lyase / succinyl-CoA ligases FT family signature 3" FT CDS 158256..159140 FT /transl_table=11 FT /gene="SCO4809" FT /gene_synonym="sucD" FT /gene_synonym="SCD63A.20" FT /product="succinyl CoA synthetase alpha chain" FT /note="SCD63A.20, sucD, succinyl CoA synthetase alpha FT chain, len: 294 aa; similar to SW:SUCD_ECOLI (EMBL:J01619) FT Escherichia coli succinyl CoA synthetase alpha chain (EC FT 6.2.1.5) SucD, 288 aa; fasta scores: opt: 986 z-score: FT 1029.6 E(): 0; 53.6% identity in 293 aa overlap and to FT TR:O87841 (EMBL:AL031013) Streptomyces coelicolor succinyl FT CoA synthetase alpha chain SucD1 SC8A6.07, 308 aa; fasta FT scores: opt: 1429 z-score: 1453.2 E(): 0; 75.9% identity in FT 286 aa overlap. Contains Pfam match to entry PF00549 FT ligase-CoA, CoA-ligases and matches to Prosite entries FT PS01216 ATP-citrate lyase / succinyl-CoA ligases family FT signature, PS00399 ATP-citrate lyase / succinyl-CoA ligases FT family active site and PS00017 ATP/GTP-binding site motif A FT (P-loop)" FT /db_xref="GOA:Q9KY55" FT /db_xref="HSSP:1JKJ" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9KY55" FT /protein_id="CAB92672.1" FT /translation="MAIWLNKDSKVIVQGMTGATGMKHTKLMLGDGTEVVGGVNPRKAG FT TSVDFDGNEVPVFGTVKEAIEKTGANVSVIFVPEKFTKDAVVEAIDAEIPLAVVITEGI FT AVHDSAAFWSYAGKKGNKTRIIGPNCPGIITPGQSNVGIIPGDITKPGRIGLVSKSGTL FT TYQMMYELRDIGFSTAVGIGGDPIIGTTHIDALAAFEADPETDLIVMIGEIGGDAEERA FT AEYISKNVTKPVVGYVAGFTAPEGKTMGHAGAIVSGSSGTAQAKKEALEAAGVKVGKTP FT TETAKLARAILAG" FT misc_feature 158670..159107 FT /note="Pfam match to entry PF00549 ligase-CoA, CoA-ligases, FT score 126.60, E-value 3.2e-34" FT misc_feature 158727..158810 FT /note="PS01216 ATP-citrate lyase / succinyl-CoA ligases FT family signature 1" FT misc_feature 158973..159014 FT /note="PS00399 ATP-citrate lyase / succinyl-CoA ligases FT family active site" FT misc_feature 159072..159095 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(159253..160281) FT /transl_table=11 FT /gene="SCO4810" FT /gene_synonym="SCD63A.21c" FT /product="conserved hypothetical protein SCD63A.21c" FT /note="SCD63A.21c, hypothetical protein, len: 342 aa; FT similar to TR:Q9Z9I2 (EMBL:AB024056) Streptomyces fradiae FT unknown protein, 306 aa; fasta scores: opt: 645 z-score: FT 632.8 E(): 8.7e-28; 44.5% identity in 281 aa overlap" FT /db_xref="GOA:Q9KY54" FT /db_xref="InterPro:IPR014284" FT /db_xref="UniProtKB/TrEMBL:Q9KY54" FT /protein_id="CAB92673.1" FT /translation="MGVAPGTVRAWESGRTTPRGRKREAYAKLLKTLAEEEAAQAQAQA FT PEQEPKPEAEPQPQPELEPQPQPQPVAAPGPTALTPAQAFDALYAFGAPALVRQTFLLT FT GRREQARESVERAFQAAWERWPEVARDRDPVGWVRATAYEYALSPWQRFRPRHRHPEPP FT PADPGDRTLLNTLLRLPARHRRTLVLYDGVGLDLPETAAETEASTPAAANRLLHAREAV FT AARLPALADPQVLHRRLAELASNERLRAAEPPAVRRGGERRARLRTRAAIAFTVALIGT FT TALTVRTAPTHYEPPVSPGQAVRGVPHRVAPGALSDEELELRQKLRDQVQDGPERLLPR FT PE" FT RBS 160469..160472 FT CDS 160474..162150 FT /transl_table=11 FT /gene="SCO4811" FT /gene_synonym="SCD63A.22" FT /product="putative integral membrane protein" FT /note="SCD63A.22, possible integral membrane protein, len: FT 558 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9KY53" FT /protein_id="CAB92674.1" FT /translation="MAGVIQTTARPAPLSLLRTRWRDRSPGLAAGLLGGVVAAVLGLAA FT CAALVTLLWISSPYPDSGPGGALHVAAALWVLAHGAELVRADTLSGTPAPVGVTPLLFL FT LLPVWLLHRAARDATDPGDGVGVAVGAAPKAGPGARPAWMASAPDTGPPPVSARVAWTG FT VVLGYLAVAGPVVLYAQGGALRPSAWWAAVCLPLVAMGAAGAGVWTAFGRPGGPVGRAL FT RVLPRKLRELMVEPDARLGAATRAAGAGAAVLVGGGALLLAVSLVWHSHAAGEAFLRLT FT EGWSGRLAVLLLCLTLVPNAAVWAAAYALGPGFVLGAGHVVAPTASAPAPLLPPFPLLA FT AVPDAGPGTPLHWAAGAVPLLAGAVVGWFTARAATAREPKERGAGPAAGVWSWRRTAAA FT AVVAAVLCAVLVALLAAFAGGPLGSAALARFGPVWWQAGGATLAWTGVVAVPVAVAARA FT WRGRSAAAREAVAEASGAEEAADGGGRRPRWVRVPVPSVGRWWRRGATKDAEAGAGAGA FT GAGVDGDVDAVPFGLYDGDGGGAYDLLPADGPGQSSPRGGQ" FT CDS complement(162289..163086) FT /transl_table=11 FT /gene="SCO4812" FT /gene_synonym="SCD63A.23c" FT /product="putative integral membrane protein" FT /note="SCD63A.23c, possible integral membrane protein, len: FT 265 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9KY52" FT /protein_id="CAB92675.1" FT /translation="MPDRSLRLLTLPQQSAQPGGRSTVLLRERPSSPPDTPSDRRNGAG FT QDGSSDQDNPFAPPPEGTPDSPWQPRHPSGDGDSQGASGSQGEGGRSPWGGRWSDRQPG FT RSPGGFGERPSGSGGPEGSGGGQGPRWDPTDPAQRRARYALLSGMWALFFALFTWPYVA FT LLLGALALYWGISALRAKPRSAADPDTPAPPAEQTGRPQRTAAISGLVTSSLAILLVAA FT SFGAQLIYSDYYTCREDALTNAAEQSCERHLPEQLRPLLGSED" FT CDS 163381..164028 FT /transl_table=11 FT /gene="SCO4813" FT /gene_synonym="purN" FT /gene_synonym="SCD63A.24" FT /product="phosphoribosylglycinamide formyltransferase" FT /note="SCD63A.24, purN, phosphoribosylglycinamide FT formyltransferase, len: 215 aa; highly similar to FT TR:AAF05726 (EMBL:AF191543) Mycobacterium paratuberculosis FT phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) FT PurN, 209 aa; fasta scores: opt: 708 z-score: 829.2 E(): 0; FT 57.6% identity in 203 aa overlap. Contains Pfam match to FT entry PF00551 formyl_transf, Formyl transferase and match FT to Prosite entry PS00373 Phosphoribosylglycinamide FT formyltransferase active site" FT /db_xref="GOA:Q9KY51" FT /db_xref="HSSP:1MEO" FT /db_xref="InterPro:IPR004607" FT /db_xref="UniProtKB/TrEMBL:Q9KY51" FT /protein_id="CAB92676.1" FT /translation="MAAKPVDRRAKRLVVLVSGSGTNLQALLDEIATTGAEAYGAEIVA FT VGADRDGIEGLARAERAGVTTFVRRVKDYGTREEWDAALAESVAAHEPDLVVSAGFMKI FT VGKEFLARFGGRFVNTHPALLPSFPGAHGVRDALAYGARVTGCTVHFVDDGVDTGPIIA FT QGVVEVRDEDYEDEGVALHERIKEVERRLLVDVVGRLARNGYRIEGRKVVIQ" FT misc_feature 163411..163971 FT /note="Pfam match to entry PF00551 formyl_transf, Formyl FT transferase, score 207.70, E-value 1e-58" FT misc_feature 163816..163887 FT /note="PS00373 Phosphoribosylglycinamide formyltransferase FT active site" FT CDS 164025..165596 FT /transl_table=11 FT /gene="SCO4814" FT /gene_synonym="purH" FT /gene_synonym="SCD63A.25" FT /product="bifunctional purine biosynthesis protein" FT /note="SCD63A.25, purH, bifunctional purine biosynthesis FT protein, len: 523 aa; highly similar to TR:AAF05727 FT (EMBL:AF191543) Mycobacterium paratuberculosis FT phosphoribosylaminoimidazolecarboxamide/formyltransferase, FT PurH, 527 aa; fasta scores: opt: 2301 z-score: 2632.5 E(): FT 0; 69.1% identity in 518 aa overlap. Contains Pfam match to FT entry PF01808 AICARFT_IMPCHas, AICARFT/IMPCHase bienzyme" FT /db_xref="GOA:Q9KY50" FT /db_xref="HSSP:1G8M" FT /db_xref="InterPro:IPR011607" FT /db_xref="UniProtKB/Swiss-Prot:Q9KY50" FT /protein_id="CAB92677.1" FT /translation="MTATAGSNKRAIRRALVSVYDKTGLEDLARGLHEAGVELVSTGST FT AGRIAAAGVPVTKVEELTGFPECLDGRVKTLHPKVHAGILADLRLESHRQQLDELGVAP FT FDLVVVNLYPFRETVASGATPDECVEQIDIGGPSMVRAAAKNHPSVAVVTSPARYADVL FT LAVEGGGFDLAARKRLAAEAFQHTAAYDVAVASWFAAEYAPVDESGFPDFLGATYERAN FT TLRYGENPHQPAALYTSPEGGGLAQAEQLHGKEMSYNNYTDTDAARRAAYDHAEPCVAI FT IKHANPCGIAIGADVAEAHRKAHDCDPVSAYGGVIAVNRPVSKEMAERVAGIFTEVIVA FT PDYEDGALEALTKKKNIRVLRAPAAPAAPVEVKPIDGGALLQVTDRLQAEGDDPATWTL FT ATGEALSEAELAELAFAWRACRAVKSNAILLAKDGASVGVGMGQVNRVDSAKLAVERAG FT AERAQGAYAASDAFFPFPDGLEILTGAGVKAVVQPGGSVRDELVVEAAKKAGVTMYFTG FT TRHFFH" FT misc_feature 164451..165395 FT /note="Pfam match to entry PF01808 AICARFT_IMPCHas, FT AICARFT/IMPCHase bienzyme, score 508.80, E-value 4.2e-149" FT CDS complement(166013..166657) FT /transl_table=11 FT /gene="SCO4815" FT /gene_synonym="SCD63A.26c" FT /product="putative secreted protein" FT /note="SCD63A.26c, possible secreted protein, len: 214 aa. FT Contains possible N-terminal signal peptide sequence" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q9KY49" FT /protein_id="CAB92678.1" FT /translation="MTPTRRSVLLSVGAVGAATALGGVLTGPAAAADGTWDSPRSANGW FT AMDPDAVGSFRVEGSPATVRLHRAAAPVLLHVARRWHYEVIPLRGSRHVLGHRTDRAVG FT AAYESNYLSGSAIALLGAGDGLWPHQEAVVRDILADCGGVVRWGTDLSPADACHFQIDV FT GPDAKALRRLTEIFHARSVHHDGPRPGAVEDPATPERRAGARRLAKAQARN" FT CDS complement(166659..169079) FT /transl_table=11 FT /gene="SCO4816" FT /gene_synonym="SC2A6.01c" FT /gene_synonym="SCD63A.27c" FT /product="hypothetical protein" FT /note="SC2A6.01c, hypothetical protein (fragment), len: FT >232 aa; similar to TR:O34320 (EMBL:AJ222587) Bacillus FT subtilis YkuG protein, 760 aa; fasta scores: opt: 439 FT z-score: 541.2 E(): 1.2e-22; 37.1% identity in 229 aa FT overlap" FT /note="SCD63A.27c, hypothetical protein (fragment), len: FT >605 aa; similar to TR:O34320 (EMBL:AJ222587) Bacillus FT subtilis YkuG protein, 760 aa; fasta scores: opt: 961 FT z-score: 1162.8 E(): 0; 34.4% identity in 596 aa overlap" FT /db_xref="GOA:Q8CJS8" FT /db_xref="InterPro:IPR015020" FT /db_xref="UniProtKB/TrEMBL:Q8CJS8" FT /protein_id="CAD55216.1" FT /translation="MNDPNVRAAQEWVNAMYDGVAEGYIRCAEDGSTGWQTVLSLTQGL FT QHELGISPTVQNFGPGTFDALVARGGIRPTETDTNLIRIINYALWCKGYYGAASAGRWT FT SVTTDSMNDLIGDAGLASAANVSNIHTRLLVQIVKALLRMDQFRRVPGGTSEIQEFQRH FT LNLTYVYGENITTMDLSPCDGVYSRDVQQAVMKALQFEIGIERSEIGGYFGSTTKARLK FT EQPTLGTGSDGALVHLFTALCVFNSPVLENGSAIPTTVRSTYTDDTEEFVRAFQKFSQL FT TVTGKSDYDTWAQLLVSTGNEYRDTTACDEAAPLTFARAQALGNAGYRIVGRYLDEHLD FT PGDDDYLGKALTSTELSDIVRGGLGVYPIFQWNGTTRANFTYDKGFEQGGVAEARAREF FT GFGRGTCIYFAVDFDATQADIDAAVLDYFRGVRAALGRTNRYTFGVYGSRNVCRNVSNR FT VGATWSFVSGLSWGFSGNLGFPLPANWSFNQIRNGTFSYGSGSFGEAWEIDRNVWRRGS FT DPGTTVLNPARSPAQDFIDLVQRLFTAALEYDAGADPARLVCQFFRQEQYNGPDWRLSL FT GAVDQGWTAALAEQGLTLAGRRNLTDPVTGTSVGTEHLMATLEMCLEYSSTTDLVSLGD FT GGGWAGDLVTFYGDWRENKDRFPNPMLFARDYLGKRDAASHFSNDQWIQDADGFNIMRL FT MRTESLGLPDAVARYYGTDSPGAGDRVCQRRYTLFHADRFDSSSSTTQTLARNLLLGRN FT SDIAVIAGTWFLISRVSLDAEDRPENIDPAQLTNFVLAYAWELQERVEAEEGK" FT CDS complement(169265..170623) FT /transl_table=11 FT /gene="SCO4817" FT /gene_synonym="SC2A6.02c" FT /product="putative serine/threonine protein kinase" FT /note="SC2A6.02c, possible serine/threonine protein kinase, FT len: 452 aa; similar to TR:CAB82017 (EMBL:AL161755) FT Streptomyces coelicolor serine/threonine protein kinase FT SCD63.10, 380 aa; fasta scores: opt: 297 z-score: 312.5 FT E(): 6.3e-10; 28.8% identity in 379 aa overlap and to FT Streptomyces coelicolor SC2A6.05c, 712 aa; fasta scores: FT opt: 1410 z-score: 1253.9 E(): 0; 68.7% identity in 339 aa FT overlap. Contains Pfam matches to entries PF00069 pkinase, FT Eukaryotic protein kinase domain and PF01471 PG_binding_1, FT Putative peptidoglycan binding domain. Contains also FT possible hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9K3K3" FT /db_xref="HSSP:1LBU" FT /db_xref="InterPro:IPR017442" FT /db_xref="UniProtKB/TrEMBL:Q9K3K3" FT /protein_id="CAB97420.1" FT /translation="MSGRPYAVPVPKGYRVGPWEVREPVASGAFATVYEAVRDASAGPD FT RTLDDGEQPRRAALKFLPTGTRTPRQLHHLRDLAEREVQLLRRLRSPRLIRMYDTLTVD FT DPDHPELDGATVLVLERAEGSLDAVLARTPAPESGPALLAQICEGLHQLHRAGWVHGDL FT KPANVLLMADGSARLADFNMAAELEGTHAYTPAFATPDYTPPELLWPEVDERGTRIRPS FT ADVWAFGVLAHVVLTGAFPLPGGTSEARSDAAMRYTRGREELRLSPALPDTWRDILRDC FT LAPTHAERTTDTATLLRRVEEAAGASRSARLPRLRPRRWRRPVLAAALAGAVVGTASLV FT YTTPWEPEPAAAAPPTCEKPVVYADADGRGYQAGHSGTWDFTIARGDGGSQVRELQCLL FT RYLHGITAVGEVDGDFGPMTQGAVVTFQERAGLDADGIVGPATWRALRDADEA" FT misc_feature complement(169274..169462) FT /note="Pfam match to entry PF01471 PG_binding_1, Putative FT peptidoglycan binding domain, score 80.00, E-value 4.8e-20" FT misc_feature complement(169751..170569) FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 131.30, E-value 1.8e-35" FT CDS complement(170620..171360) FT /transl_table=11 FT /gene="SCO4818" FT /gene_synonym="SC2A6.03c" FT /product="hypothetical protein SC2A6.03c" FT /note="SC2A6.03c, unknown, len: 246 aa; similar to FT Streptomyces coelicolor SC2A6.06c, 243 aa; fasta scores: FT opt: 1097 z-score: 1146.8 E(): 0; 67.6% identity in 244 aa FT overlap" FT /db_xref="UniProtKB/TrEMBL:Q9K3K2" FT /protein_id="CAB97421.1" FT /translation="MYSIIVVPPSCGSVAEQLRIGTGERIEFGRAESGGGLTIAHAGVP FT RLAGEIAAHRTFWLLSNLREDQTYVVENPEGAGEHIKVAPGRVDAPVPFELSRVTLPAA FT GDLLSFDVWAPRHAFRSVDRGALDGTGTVPAFALDRTKRYFAVLAALCERRLRGEPRAP FT LPAVEEIVERLRPSWPKVSRSAVYWNIDYLAVKLRLRPGPEAAGPGQRTHGKKESLASL FT ALRFDLVREDDLLVLAPVASRAER" FT RBS complement(170626..170629) FT CDS complement(171572..172042) FT /transl_table=11 FT /gene="SCO4819" FT /gene_synonym="SC2A6.04c" FT /product="putative secreted protein" FT /note="SC2A6.04c, possible secreted protein, len: 156 aa. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="UniProtKB/TrEMBL:Q9K3K1" FT /protein_id="CAB97422.1" FT /translation="MNILKPAALLLAATALAAGSTAAATAADSPGGTRVTGLQQTAGQV FT LADSPKPLRVTADAVEYEGLTVTDAPVTKGAQDLPCDYGHLCMVVKGTKFDFYKCQTWN FT LTNWTGDGPFTNNQTRGTVAKFFNKDGSVRWTSTAYQAGTASWDPIWSLRPC" FT CDS complement(172141..174279) FT /transl_table=11 FT /gene="SCO4820" FT /gene_synonym="SC2A6.05c" FT /product="putative serine/threonine protein kinase" FT /note="SC2A6.05c, possible serine/threonine protein kinase, FT len: 712 aa; C-terminal region similar to TR:O53510 FT (EMBL:AL021957) Mycobacterium tuberculosis serine/threonine FT protein kinase MTV021.09, 399 aa; fasta scores: opt: 289 FT z-score: 239.4 E(): 7.5e-06; 30.6% identity in 340 aa FT overlap and to Streptomyces coelicolor SC2A6.02c, 452 aa; FT fasta scores: opt: 1410 z-score: 964.7 E(): 0; 68.7% FT identity in 339 aa overlap. Contains 2 Pfam matches to FT entry PF00069 pkinase, Eukaryotic protein kinase domain. FT Contains also possible hydrophobic membrane spanning FT regions, 3x degenerate repeat: FT (T/H)GTGTGT(8)AHPA(K/E)GDTD(N/D)PG(16) and 2x degenerate FT repeat: PSRA(Q/H)TDTAHPAEGDTD(D/N)PGHTSGNGTTGTDGT(R/G)S(7)" FT /db_xref="GOA:Q9K3K0" FT /db_xref="InterPro:IPR017442" FT /db_xref="UniProtKB/TrEMBL:Q9K3K0" FT /protein_id="CAB97423.1" FT /translation="MTEPYAVPVPRGYRVGVWEVHAPIATGAFGSVYAARRTGGDDTKA FT SPTRPGGDDNTKAPPTRPGGDGTGHRPSRPGTTDTAGTDDSHGTGTGTGTGTPSRAQTD FT TAHPAEGDTDDPGHTSGNGTTGTDGTRRSHGTGTGTPSRAHTDTAHPAEGDTDNPGHTS FT GNGTTGTDGTGRSHGTGTGTGTHNPSRVQTGAAHPAKGDTDNPGRTGGDGTARRPGRAG FT VVGAGRGGDAGGEVPDTVALKFLPTGTGTPRQLAHLRDLVEREVELLRRLRRPRLIRMY FT ETLTVDDPAHPRLDGATVLVLERAEGSLSALLAATPRPPAGPALLAQVCEGLQQLHRAG FT WVHGDLKPANVLLMADGSARLADFNMAAELEGTHAYTPAFATPDYTPPELLWSEIGERG FT RRIRPSADVWAFGVLAHLVLTGSFPLPGGTPTARRDAAVAYARGGHELRLSPEPPPGWR FT EIVRACLTRTHADRIGTDALLRRVTGTTEGASGGAGFSPRTRARPRRRVLAALAAGLLA FT LAALGYGVARWAGDGREPAAGPRPGGTGSVAAASYGAAELRTDRDVPPAYRLLIVETAH FT DCDREEVSPALIAAMLKVESDFDPDLADPAKDEYGIARWTPSVLRWWMNEDGTPGETVP FT QPPFPPAESVPAMGRYLCWIAPRLDAGLPGDRSVLVAVAYRTSYRKVNDAGGVPPKYRD FT YADRVAHHLKEYTPRRGK" FT misc_feature complement(172837..173565) FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 93.70, E-value 6.6e-25" FT repeat_region complement(173659..174009) FT /note="3x degenerate repeat translated in SC2A6.05c" FT repeat_region complement(173752..173988) FT /note="2x degenerate repeat translated in SC2A6.05c" FT misc_feature complement(174169..174228) FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 6.00, E-value 1.4" FT CDS complement(174276..175007) FT /transl_table=11 FT /gene="SCO4821" FT /gene_synonym="SC2A6.06c" FT /product="hypothetical protein SC2A6.06c" FT /note="SC2A6.06c, unknown, len: 243 aa; similar to FT Streptomyces coelicolor SC2A6.03c, 246 aa; fasta scores: FT opt: 1097 z-score: 1069.3 E(): 0; 67.6% identity in 244 aa FT overlap" FT /db_xref="UniProtKB/TrEMBL:Q9K3J9" FT /protein_id="CAB97424.1" FT /translation="MVPPPTTEDEGTGTQYRLAPGERLVFGRSVPGGGLRIGHDGVSRR FT AGEIAAHGTFWTLSNLSAHQTYVVENPEGAGEHIKVAPGRLDAPVPFEFSRIVLPAAGD FT LLPVEVWAPRHDYLRGEDGTDGEPTAPAFSVDRTKRYFAVLAALCEPRLRGAPHAPLPT FT MDQVVERLRPAWPAASRTSVQWNIDYLAVKLRLKPGPETAEPGPRLNGKKESLVSLALR FT FDLVREDDLVVLAAPSGQVRR" FT CDS complement(175148..175735) FT /transl_table=11 FT /gene="SCO4822" FT /gene_synonym="SC2A6.07c" FT /product="putative integral membrane protein" FT /note="SC2A6.07c, possible integral membrane protein, len: FT 195 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9K3J8" FT /protein_id="CAB97425.1" FT /translation="MSFGDPNNPYGPPQGGQQPNYGYPQQPQGQPGYGYPAAPPVQQPY FT GGGYGPGPTEMPGITRAAQIMLAVIAAAHLIVAAVYAYNLSQWDEVMLEAGVSGDAEAE FT RFLELGKGIVVFFLALAAVYAVLGLVLVLQYAKGSNAVRVCSIVYGSLAIVTGIFTLAI FT YGLGLLIMIVSILLIVFAAKRASAEWFRRPRY" FT RBS complement(175746..175750) FT CDS 175858..176034 FT /transl_table=11 FT /gene="SCO4823" FT /gene_synonym="SC2A6.08" FT /product="hypothetical protein SC2A6.08" FT /note="SC2A6.08, unknown, len: 58 aa. Contains a TTA FT leucine codon, possible target for bldA regulation" FT /db_xref="UniProtKB/TrEMBL:Q9K3J7" FT /protein_id="CAB97426.1" FT /translation="MTELLLVQPARKALCKRNNIDHERIGWDVSRGVRKVPVRCPHADL FT IGTGGRSSARMGA" FT misc_feature 175870..175872 FT /gene="none" FT /note="TTA leucine codon. Possible target for bldA FT regulation" FT RBS 176019..176022 FT CDS 176031..176885 FT /transl_table=11 FT /gene="SCO4824" FT /gene_synonym="folD" FT /gene_synonym="SC2A6.09" FT /product="bifunctional protein (methylenetetrahydrofolate FT dehydrogenase and methenyltetrahydrofolate cyclohydrolase)" FT /note="SC2A6.09, folD, bifunctional protein FT (methylenetetrahydrofolate dehydrogenase and FT methenyltetrahydrofolate cyclohydrolase), len: 284 aa; FT highly similar to SW:FOLD_ECOLI (EMBL:M74789) Escherichia FT coli FolD, bifunctional protein (methylenetetrahydrofolate FT dehydrogenase (EC 1.5.1.5); methenyltetrahydrofolate FT cyclohydrolase (EC 3.5.4.9)), 287 aa; fasta scores: opt: FT 784 z-score: 905.2 E(): 0; 44.2% identity in 278 aa FT overlap. Contains Pfam match to entry PF00763 THF_DHG_CYH, FT Tetrahydrofolate dehydrogenase/cyclohydrolase" FT /db_xref="GOA:Q9K3J6" FT /db_xref="HSSP:1A4I" FT /db_xref="InterPro:IPR000672" FT /db_xref="UniProtKB/Swiss-Prot:Q9K3J6" FT /protein_id="CAB97427.1" FT /translation="MTAQILDGKATAAAIKSELTARVAALKERGVTPGLGTVLVGDDPG FT SQKYVAGKHRDCAQVGIASIQRELPATATQEEIEAVVRELNEDPACTGYIVQLPLPRGI FT DENRILELMDPDKDADGLHPMNLGRLVLNEPAPLPCTPNGILTLLRRYGVEIKGAEVVV FT VGRGVTIGRPMPLLLTRRSENATVTQCHTGTRDLAAHLKRADIVIAAAGSPHLVRPEDV FT KPGAAVLDVGVSRNAEGKIMGDVHPGVAEVAAWISPNPGGVGPMTRAQLLVNVVEAAER FT SAG" FT misc_feature 176073..176867 FT /note="Pfam match to entry PF00763 THF_DHG_CYH, FT Tetrahydrofolate dehydrogenase/cyclohydrolase, score FT 472.40, E-value 3.6e-138" FT RBS 176867..176870 FT CDS 176875..177411 FT /transl_table=11 FT /gene="SCO4825" FT /gene_synonym="SC2A6.10" FT /product="putative integral membrane protein" FT /note="SC2A6.10, possible integral membrane protein, len: FT 178 aa; similar to TR:O32878 (EMBL:Z98271) Mycobacterium FT leprae hypothetical 9.6 kD protein MLCB1779.16c, 91 aa; FT fasta scores: opt: 148 z-score: 174.2 E(): 0.032; 27.5% FT identity in 80 aa overlap. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9K3J5" FT /protein_id="CAB97428.1" FT /translation="MPAEDTNAERPGDARAPEDGAPRASQASGEPDGITVRDPVSAPDA FT EGRPRRTTRRFPLFTRDTARPEGGGRAAPGDAPAPARQWPVLTVTLLVGVGLLLTALDV FT FRWGLVLVGAALLLGAALRWTMPRVGMLAVRSRFTDIATYGVLGLSIALLALMAQPNPV FT LEIPFLKDTLHFTVS" FT CDS 177708..179204 FT /transl_table=11 FT /gene="SCO4826" FT /gene_synonym="SC2A6.11" FT /product="putative membrane protein" FT /note="SC2A6.11, possible membrane protein, len: 498 aa. FT Contains 5x degenerate repeat: (G/D)AY(G/D)(E/G)-(3) and FT possible hydrophobic membrane spanning region" FT /db_xref="GOA:Q9K3J4" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q9K3J4" FT /protein_id="CAB97429.1" FT /translation="MGSQKRVPRGGTPRAGTSGETTSTSPGEEGEAVPRWKALPEELDP FT QIREFTSQLRRLVDRSELSVASVADATGYSKTSWERYLNGRLLAPKGAIVALAEVTETN FT PVHLTTMWELAERAWSRSEMRHDMTMEAIRISQARAALGELGTPAARSGGAAAKSGHGG FT RTGKGSRTGRHGGGTSAASGIAGPAGVSPTLPPTVPAQPTAADSPDSALGAGRDGGAPG FT VSSAPSPGGATDGNSWGLAGYRGPAPTGDRTARSGVRPGTEEPVGPAGPAGPHGPGPAG FT AYDEPRSDAYGGPRPDAYGGTRSDAYGESPSDAYGEPPHGGASASRRTPPGGGGNKRVT FT TVIAGVVGVLVVIAGAFFLLRDGGDKKNEGTKPSPSPTVSSEPKLPPGVKCSGDACTGK FT DPEAMGCGGDLVTTGATAVVGTAAVEVRYSEVCGAAWARVTQAAQGDEVQVSAGGAGEQ FT RATVGTVGSTVAYTPMVAVKSAADATACATLAAGTQGCTK" FT repeat_region 178548..178667 FT /note="5x degenerate repeat translated in SC2A6.11" FT RBS 179557..179561 FT CDS 179567..180556 FT /transl_table=11 FT /gene="SCO4827" FT /gene_synonym="mdh" FT /gene_synonym="SC2A6.12" FT /product="malate dehydrogenase" FT /note="SC2A6.12, mdh, malate dehydrogenase, len: 329 aa; FT similar to SW:MDH_THEFL (EMBL:J02598) Thermus aquaticus FT malate dehydrogenase (EC 1.1.1.37) Mdh, 327 aa; fasta FT scores: opt: 1398 z-score: 1643.5 E(): 0; 64.5% identity in FT 327 aa overlap. Contains Pfam match to entry PF00056 ldh, FT lactate/malate dehydrogenase and match to Prosite entry FT PS00068 Malate dehydrogenase active site signature" FT /db_xref="GOA:Q9K3J3" FT /db_xref="HSSP:1BDM" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/Swiss-Prot:Q9K3J3" FT /protein_id="CAB97430.1" FT /translation="MTRTPVNVTVTGAAGQIGYALLFRIASGQLLGADVPVKLRLLEIT FT PALKAAEGTAMELDDCAFPLLQGIEITDDPNVAFDGANVALLVGARPRTKGMERGDLLE FT ANGGIFKPQGKAINDHAADDIKVLVVGNPANTNALIAQAAAPDVPAERFTAMTRLDHNR FT ALTQLAKKTGSTVADIKRLTIWGNHSATQYPDIFHATVAGKNAAETVNDEKWLADEFIP FT TVAKRGAAIIEARGASSAASAANAAIDHVYTWVNGTAEGDWTSMGIPSDGSYGVPEGII FT SSFPVTTKDGSYEIVQGLDINEFSRARIDASVKELSEEREAVRGLGLI" FT misc_feature 179585..180538 FT /note="Pfam match to entry PF00056 ldh, lactate/malate FT dehydrogenase, score 322.00, E-value 6.8e-93" FT misc_feature 180032..180070 FT /note="PS00068 Malate dehydrogenase active site signature" FT CDS 180785..182314 FT /transl_table=11 FT /gene="SCO4828" FT /gene_synonym="gbsA" FT /gene_synonym="SC2A6.13" FT /product="betaine aldehyde dehydrogenase" FT /note="SC2A6.13, gbsA, betaine aldehyde dehydrogenase, len: FT 509 aa; highly similar to SW:DHAB_BACSU (EMBL:U47861) FT Bacillus subtilis betaine aldehyde dehydrogenase (EC FT 1.2.1.8) GsbA, 490 aa; fasta scores: opt: 1874 z-score: FT 2114.6 E(): 0; 56.0% identity in 495 aa overlap. Contains FT Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase FT family and matches to Prosite entries PS00687 Aldehyde FT dehydrogenases glutamic acid active site and PS00070 FT Aldehyde dehydrogenases cysteine active site" FT /db_xref="GOA:Q9K3J2" FT /db_xref="HSSP:1O04" FT /db_xref="InterPro:IPR016162" FT /db_xref="UniProtKB/TrEMBL:Q9K3J2" FT /protein_id="CAB97431.1" FT /translation="MANSTHTPAERAHRTIHAGGEWLAASSGATREILDPADAVAFAVV FT AEGDEKDTDLAVAAARRAFDAGDWPHTPVAERAALLRRVAGLLVRDREKLGLLESRDAG FT KTVEEGRVDIDCVADAFRYFADLVAGEAPGRVVDAGSPEVHSVVVHEPVGVCAMITPWN FT YPLLQASWKIAPALAAGNTFVIKPSEITPMTTIALIDLLVEAGLPTGVANIVTGPGHTV FT GARLAEHPDVDLVSFTGGLTSGVKVAQAAAVTVKKVALELGGKNPNVVFADACATEEGF FT DTAVDQALNAAFMHSGQVCSAGGRLIVEESVRERFVAELARRAERIRLGRGTEEGVECG FT PLVSAQQRAKTEDYVASALAEGAELRCGGKRPEPSPQRPESGYFYEPTVLDHCHREMRV FT VREEVFGPVLTVETFRTEDEAVALANDTEYGLAGAVWTADAGRARRVAGRLRHGTVWIN FT DFHPYLPQAEWGGFGKSGVGRELGPAGLAEYRESKHVYQNLAPKPVRWFSG" FT misc_feature 180845..182281 FT /note="Pfam match to entry PF00171 aldedh, Aldehyde FT dehydrogenase family, score 612.90, E-value 1.8e-180" FT misc_feature 181562..181585 FT /note="PS00687 Aldehyde dehydrogenases glutamic acid active FT site" FT misc_feature 181661..181696 FT /note="PS00070 Aldehyde dehydrogenases cysteine active FT site" FT RBS 182360..182364 FT CDS 182371..183903 FT /transl_table=11 FT /gene="SCO4829" FT /gene_synonym="SC2A6.14" FT /product="putative oxidoreductase" FT /note="SC2A6.14, probable oxidoreductase, len: 510 aa; FT similar to SW:ALKJ_PSEOL (EMBL:X65936) Pseudomonas FT oleovorans alcohol dehydrogenase [acceptor] (EC 1.1.99.-) FT AlkJ, 558 aa; fasta scores: opt: 474 z-score: 541.0 E(): FT 1.2e-22; 31.1% identity in 541 aa overlap. Contains Pfam FT match to entry PF00732 GMC_oxred, GMC oxidoreductases and FT match to Prosite entry PS00624 GMC oxidoreductases FT signature 2" FT /db_xref="GOA:Q9K3J1" FT /db_xref="InterPro:IPR012132" FT /db_xref="UniProtKB/TrEMBL:Q9K3J1" FT /protein_id="CAB97432.1" FT /translation="MPETTHVYDYVVIGGGTAGSVIASRLTENPDVTVAVIEGGPSDVG FT RDDVLTLRRWMGLLGGELDYDYPTTEQPRGNSHIRHSRARVLGGCSSHNTLIAFKPLPS FT DWDEWEAAGAKGWGAVQMEAYFARLKNNIVPVDEKDRNAIARDFVDSAQKTLEVPRVEG FT FNKKPFTEGVGFFDLAYHPENNKRSSASVAYLHPVMDERPNLTLMLETWAYRLELDGTR FT AEGVHVRTKDGEEILVKARGEVVLCAGAVDSPRLLLHSGIGPREDLEALGIPVALDLPG FT VGENLLDHPESVIVWETNGPIPDNSAMDSDAGLFVRRDPEHAGPDLMFHFYQIPFTDNP FT ERLGYQRPEFGVSMTPNIPKPKSRGRLYLTSADPSEKPALDFRYFTDEDDYDGRTLVDG FT IRIAREIAESQPLAGWLKREVCPGPDVTGDAELSEYARKVAHTVYHPAGTCRMGAATDE FT QAVVDPELRVRGLTGLRIADASVFPTMPAVNPMIGVLMVGERAVELIGGDAR" FT misc_feature 182392..183873 FT /note="Pfam match to entry PF00732 GMC_oxred, GMC FT oxidoreductases, score 386.80, E-value 2.2e-112" FT misc_feature 183115..183159 FT /note="PS00624 GMC oxidoreductases signature 2" FT CDS 183900..185084 FT /transl_table=11 FT /gene="SCO4830" FT /gene_synonym="SC2A6.15" FT /product="putative glycine betaine ABC transport system FT ATP-binding protein" FT /note="SC2A6.15, probable glycine betaine ABC transport FT system ATP-binding protein, len: 394 aa; similar to FT SW:OPAA_BACSU (EMBL:U17292) Bacillus subtilis glycine FT betaine transport ATP-binding protein OpuAa, 418 aa; fasta FT scores: opt: 1015 z-score: 1043.6 E(): 0; 48.5% identity in FT 338 aa overlap. Contains Pfam match to entry PF00005 FT ABC_tran, ABC transporter and matches to Prosite entries FT PS00017 ATP/GTP-binding site motif A (P-loop) and PS00211 FT ABC transporters family signature" FT /db_xref="GOA:Q9K3J0" FT /db_xref="HSSP:1B0U" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9K3J0" FT /protein_id="CAB97433.1" FT /translation="MSTTGKNTTAAATDTVTERPPVFSVDGLWKVFGPKAARVPADPDL FT TALSPAELRSRTGCTAAVADVSFDVRKGEVFVVMGLSGSGKSTLVRCLTRLIEPTAGSI FT VIDGEDVRAMDRSRLRELRRHRAAMVFQHFGLLPHRTVLDNVAYGLEVQGMGRAERRER FT AAAIVAKVGLEGLEQRRPGQLSGGQRQRVGLARALAVDPEVLLFDEPFSALDPLIRRDM FT QEEVVRLHREEGRTMVFITHDLQEALKLGDRIALMRDGRVVQLGTPEEIVGSPADDYVR FT EFVRDVPREQVLTVRTAMRPAANADEAGTGPAIRPEATVSEAIEAVARAGSAARVMSDG FT RCLGVVDAADLLSVVAGTAAAGSRAAGAARVGAAATGERREPTDPRPATTEEPV" FT misc_feature 184116..184679 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 247.80, E-value 1.5e-70" FT misc_feature 184137..184160 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 184449..184493 FT /note="PS00211 ABC transporters family signature" FT RBS 185072..185075 FT CDS 185084..187030 FT /transl_table=11 FT /gene="SCO4831" FT /gene_synonym="SC2A6.16" FT /product="putative glycine betaine ABC transport system FT integral membrane protein" FT /note="SC2A6.16, probable glycine betaine ABC transport FT system integral membrane protein, len: 648 aa; N-terminal FT domain similar to SW:OPAB_BACSU (EMBL:U17292) Bacillus FT subtilis glycine betaine transport system permease protein FT OpuAb aa; fasta scores: opt: 662 z-score: 724.1 E(): FT 7.5e-33; 38.7% identity in 269 aa overlap and C-terminal FT domain similar to TR:Q9RR45 (EMBL:AF039835) Listeria FT monocytogenes putative glycine betaine membrane transport FT protein GbuB, 282 aa; fasta scores: opt: 594 z-score: 650.5 FT E(): 9.5e-29; 36.5% identity in 263 aa overlap. Contains 2x FT Pfam matches to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component and match to Prosite entry PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign. Contains also possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q9K3I9" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9K3I9" FT /protein_id="CAB97434.1" FT /translation="MATITATARKPAPPGILTHRAVRKLLILALAAAILAPIAATQWSG FT ATWPSALTVDVSEPLGKASDWIIDNRDTHPLFLYFFGHVSNIVVIAVRAVYLALLAVGW FT AGVTAIGALVAWRVAGVRLAAGTAAAFLACGLLGMWVPTMQTLALMVVAVLASVAVGAL FT LGLAAGLSDRMDRVLRPVLDTMQVLPAFAYLLPVVLVFGIGVPAAVLATVVYAAPPMAR FT LTSLGLRGADREVLEAVESLGTTARQRLLTARIPLARKELLLGVNQTIMMALSMAVIAS FT VIGAGGLGDRVYQALASVDVGAALAAGIPIVLLAVVLDRVTGAAGERLGESGKSPVTWL FT YALVVAAAVALAGRLAGFLDWPDGWDLNIAEPVNRAVDWMTAHLYSGVPVVGGTADWAA FT HFTSWVLNPLREGLQWLPWWSVLLIVAALAWLIGTWRTALTAVLAMAAIGVLGVWNPSL FT DTLSQVLAAVAVTLVVGFATGIAAARSDRFERLLRPVLDVFQTMPQFVYLIPVVALFGV FT GRAPAVAAAVVYALPAVVRITAQGLRQVDPAAMESARSLGATSGQQLRQVQLPLARPAL FT LLAANQGVVLVLAVVIIGGLVGGGALGYQVVFGLAQGDLATGLVAGAAIVCLGLMLDRV FT TQPTERRTTKKGA" FT misc_feature 185762..185974 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 27.80, E-value 0.00026" FT misc_feature 186704..186961 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 21.10, E-value 0.027" FT misc_feature 186707..186793 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT RBS 187022..187025 FT CDS 187032..188000 FT /transl_table=11 FT /gene="SCO4832" FT /gene_synonym="SC2A6.17" FT /product="putative glycine betaine-binding lipoprotein" FT /note="SC2A6.17, possible glycine betaine-binding FT lipoprotein, len: 322 aa; similar to SW:PROX_ECOLI FT (EMBL:M24856) Escherichia coli glycine betaine-binding FT periplasmic protein precursor ProX or ProU, 330 aa; fasta FT scores: opt: 112 z-score: 137.8 E(): 3.4; 21.8% identity in FT 325 aa overlap. Contains correctly situated match to FT Prosite entry PS00013 Prokaryotic membrane lipoprotein FT lipid attachment site and possible N-terminal region signal FT peptide sequence" FT /db_xref="GOA:Q9K3I8" FT /db_xref="InterPro:IPR007210" FT /db_xref="UniProtKB/TrEMBL:Q9K3I8" FT /protein_id="CAB97435.1" FT /translation="MRLRPRIRMTSALAGVAALTLLTGCGAADMTKQASPYANAQGART FT VTLSVQSWVGAQANVAVAQYLLEHELGYRVDTVQVDEVPAWDALSQGRVDAILEDWGHP FT EQEQRYVQDKKTIAPGGDLGVTGHIGWFVPTYFAKKHPDVTNWKNLNKYADLLRTAESG FT GKGQLLDGSPSYVTNDKALVKNLDLDYQVVFAGSEAAQITQMQQFAKERKPFLSYWYTP FT QWLMEKVPMTEVKLPPYEEGCDADPEKVACAYPVTPLQKYLNAGFAKDGGKAAEFLKRF FT TWTTEDQNQVSLMIAQQKMRPEEAAKKWVDGHESVWKKWLP" FT misc_feature 187074..187106 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(188004..188735) FT /transl_table=11 FT /gene="SCO4833" FT /gene_synonym="SC5G8.01c" FT /gene_synonym="SC2A6.18c" FT /product="putative phosphorylmutase" FT /note="SC5G8.01c, partial CDS, possible phosphorylmutase, FT len: >101 aa; similar to many e.g. SW:P11435 (CPPM_STRHY) FT carboxyvinyl-carboxyphosphonate phosphorylmutase from FT Streptomyces hygroscopicus (294 aa) fasta scores; opt: 185, FT z-score: 234.7, E(): 1.3e-05, 43.0% identity in 93 aa FT overlap." FT /note="SC2A6.18c, possible transferase (fragment), len: FT >172 aa; similar to C-terminal part of SW:CPPM_BACSU FT (EMBL:D84432) Bacillus subtilis putative FT carboxyvinyl-carboxyphosphonate phosphorylmutase (EC FT 2.7.8.23) YqiQ, 301 aa; fasta scores: opt: 158 z-score: FT 187.0 E(): 0.0062; 31.0% identity in 116 aa overlap" FT /db_xref="GOA:Q8CJS7" FT /db_xref="InterPro:IPR015813" FT /db_xref="UniProtKB/TrEMBL:Q8CJS7" FT /protein_id="CAD55217.1" FT /translation="MSHAAAFRALHHGRVPDDPLVLPGPWDAASARVCVEAGFPALATP FT SAGVAASLGYEDGQTPADEMFAAVARIVRAVDVPVSADVEDGYGLAPKELVERLLEVGV FT VGCNLEDSTDGGLKDPAEHAEWLAGVREEAGDRLFLNARIDTFIRGVDDPGAAIERAAA FT YVAAGADCVYPIAAPTALLPLLRSGIQGPVNVFARPGQGPAPAELGGLGATRITFGPGL FT QRHAEQSVREAAAGLAGRPVK" FT CDS complement(188732..189178) FT /transl_table=11 FT /gene="SCO4834" FT /gene_synonym="SC5G8.02c" FT /product="conserved hypothetical protein" FT /note="SC5G8.02c, conserved hypothetical protein, len: 148 FT aa; similar to many eg. TR:P96684 (EMBL:AB001488) FT hypothetical protein from Bacillus subtilis (147 aa) fasta FT scores; opt: 329, z-score: 442.4, E(): 3.5e-17, 46.7% FT identity in 105 aa overlap and TR:CAB56729 (EMBL:AL121600) FT hypothetical protein from Streptomyces coelicolor (173 aa) FT fasta scores; opt: 298, z-score: 400.8, E(): 7.2e-15, 38.9% FT identity in 149 aa overlap. Also similar to neighbouring FT CDS 03c fasta scores; opt: 530, z-score: 623.7, E(): FT 3.2e-29, 62.3% identity in 138 aa overlap" FT /db_xref="InterPro:IPR003779" FT /db_xref="UniProtKB/TrEMBL:Q9KZB2" FT /protein_id="CAB89053.1" FT /translation="MTARTQLLDREVGKALSALSAAAKKGLGDPVLAELVMIRASQLNH FT CAFCLDMHLALARKNGEGEERLGLLAAWEEAADLYDGRERAALALTEAMTVLTEGFVPD FT EVYEEAAVHFDDGELAHLIGLITVINSWNRLMVSRRVPPGGYTP" FT RBS complement(188745..188749) FT CDS complement(189175..189684) FT /transl_table=11 FT /gene="SCO4835" FT /gene_synonym="SC5G8.03c" FT /product="conserved hypothetical protein" FT /note="SC5G8.03c, conserved hypothetical protein, len: FT 169aa; similar to many eg. TR:P96684 (EMBL:AB001488) FT hypothetical protein from Bacillus subtilis (147 aa) fasta FT scores; opt: 386, z-score: 504.8, E(): 1.2e-20, 42.6% FT identity in 136 aa overlap and TR:CAB66282 (EMBL:AL136519) FT hypothetical protein from Streptomyces coelicolor (161 aa) FT fasta scores; opt: 324, z-score: 425.2, E(): 3.2e-16, FT 45.0% identity in 129 aa overlap. Also similar to FT neighbouring CDS SC5G8.02c fasta scores; opt: 530, z-score: FT 667.2, E(): 1.2e-31, 62.3% identity in 138 aa overlap" FT /db_xref="InterPro:IPR003779" FT /db_xref="UniProtKB/TrEMBL:Q9KZB1" FT /protein_id="CAB89054.1" FT /translation="MTTPTDDTKTTDYAAEVPVRLNWSQHAPEVYKAMIRLETVAKRGL FT DPALYELVKIRASQINHCAFCLDMHTKDALAAGESVERIVQLAAWEESRHFYTEKELAA FT IELTEAVTVLTDGFVPDEVYEKAAKHFDEPELAQLIAAITTINAWNRFGVTCRMTPGHY FT TPGGNA" FT RBS complement(189185..189189) FT CDS 189732..191120 FT /transl_table=11 FT /gene="SCO4836" FT /gene_synonym="SC5G8.04" FT /product="putative gntR-family regulator" FT /note="SC5G8.04, possible gntR-family regulator, len: 462 FT aa; similar to many proposed regulators eg. TR:AAF01064 FT (EMBL:AF189258) transcriptional regulator (fragment) from FT Streptomyces venezuelae (507 aa) fasta scores; opt: 1010, FT z-score: 1115.6, E(): 0, 45.2% identity in 389 aa overlap. FT Contains Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family." FT /db_xref="GOA:Q9KZB0" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9KZB0" FT /protein_id="CAB89055.1" FT /translation="MANSWATLGVDLHLEPTGPGLRRGLTDALREAVRTGRLGPGTRLP FT SSRVLAADLGIARNTVADAYADLVAEGWLTARQGSGTRVADRVAAPPAEASARRPREPA FT RPLHDLRPGSPDLASFPRVEWLRAARRAVTAAPNEAFGYGDPRGHPELRGALSAYLARA FT RGVRAAPDHLLICGGVAHALVVLAAVLRARGVRTVAVESYGLHVHRDLLEAAGLRTVPL FT PVDDRGADPGALTDAGAVLLTPAHQFPTGVPLHPDRRAAVVDWARRTGALILEDDYDGE FT FRYDRQPVGALQGLAPDHVVYLGTASKSLAPGLRLAWAVLPPGLADEITATRGGSDTCG FT VLEQLTLAEFLASGAYDRHVRASRLRYRRRRDALVAALAGRVPEVRIAGIAAGLHAVLG FT LPPGTEQQVLRSAAWQGLGLHGLSVFRHPRATTDPLDAVVVGYGTPPDHAWTGALDALC FT RALP" FT misc_feature 189804..189983 FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 71.70, E-value FT 1.3e-20" FT RBS 191326..191330 FT CDS 191336..192781 FT /transl_table=11 FT /gene="SCO4837" FT /gene_synonym="glyA1" FT /gene_synonym="SC5G8.05" FT /product="serine hydroxymethyltransferase" FT /note="SC5G8.05, glyA1, serine hydroxymethyltransferase, FT len: 481 aa; strongly similar to many e.g. SW:P34895 FT (GLYA_HYPME) serine hydroxymethyltransferase from FT Hyphomicrobium methylovorum (434 aa) fasta scores; opt: FT 912, z-score: 1044.8, E(): 0, 44.2% identity in 459 aa FT overlap. Contains two Pfam matches to entry PF00464 SHMT, FT Serine hydroxymethyltransferase." FT /db_xref="GOA:Q9KZA9" FT /db_xref="HSSP:1DFO" FT /db_xref="InterPro:IPR019798" FT /db_xref="UniProtKB/TrEMBL:Q9KZA9" FT /protein_id="CAB89056.1" FT /translation="MPAEISPESTAYRAALDVIRAVEPRVADAIGQEVADQREMLKLIA FT SENYASPATLLAMGNWFSDKYAEGTIGRRFYAGCRNVDTVESLAAEHARELFGARHAYV FT QPHSGIDANLVAFWAVLGARVEVPFLEKTGARQVNDLTDADWAELRQAFGNQRMLGMSL FT DAGGHLTHGFRPNISGKMFDQRSYGTDPATGLIDYEALRASAREFKPLIIVAGYSAYPR FT LVNFRIMREIADEVGATLMVDMAHFAGLVAGKVLTGDFDPVPHAQIVTTTTHKSLRGPR FT GGMVLCDDSLKDQVDRGCPMVLGGPLPHVMAAKAVALAEARRPAFQDYAQRIVDNARAL FT AEGLTKRGATLVTGGTDNHLNLIDVASSYGLTGRQAEAALLDSGIVTNRNAIPADPNGA FT WYTSGIRIGTPALTTRGLGTAEMDEVAGLIDRVLTATEPGTTKSGAPSKASHVLDAKVA FT DEISHRATDLVAGFPLYPEIDLG" FT misc_feature 191390..191698 FT /note="Pfam match to entry PF00464 SHMT, Serine FT hydroxymethyltransferase, score 107.80, E-value 1.1e-31" FT misc_feature 191804..192622 FT /note="Pfam match to entry PF00464 SHMT, Serine FT hydroxymethyltransferase, score 423.00, E-value 1.7e-126" FT CDS complement(192796..193452) FT /transl_table=11 FT /gene="SCO4838" FT /gene_synonym="SC5G8.06c" FT /product="hypothetical protein" FT /note="SC5G8.06c, unknown, len: 218aa;" FT /db_xref="UniProtKB/TrEMBL:Q9KZA8" FT /protein_id="CAB89057.1" FT /translation="MRWWAGAGAALAAVLWTGVPGTAVADGTAPLVDPDVAVVVWTGTG FT RTTSWHAGERDFDRLRSLLDPSYSGSEPVPQDWTRDRRPPVRCTVLWGLTGVGGWPQTE FT RAPGGDVAMLRQDQLFLAEDGTPWVRTDPAPDVADDDIRWHRVDRDTYAWLAGEGFFAK FT DGTGDAEEDGGPDGVWWAAAGLGTGVAGTLLVRRAADRLRTGPPRGEPRQELIDL" FT RBS complement(193458..193464) FT CDS 193569..194588 FT /transl_table=11 FT /gene="SCO4839" FT /gene_synonym="trpS2" FT /gene_synonym="SC5G8.07" FT /product="tryptophanyl-tRNA synthetase" FT /note="SC5G8.07, trpS2, tryptophanyl-tRNA synthetase, len: FT 339aa; strongly similar to many eg. SW:P00953 (SYW_BACST) FT tryptophanyl-tRNA synthetase from Bacillus FT stearothermophilus (328 aa) fasta scores; opt: 1195, FT z-score: 1347.2, E(): 0, 55.7% identity in 325 aa overlap. FT Also similar to TR:Q9X8F8 (EMBL:AL049819) trpS, FT tryptophanyl-tRNA synthetase (fragment) from Streptomyces FT coelicolor (208 aa) fasta scores; opt: 618, z-score: FT 703.4, E(): 1e-31, 50.5% identity in 204 aa FT overlap.Contains Pfam match to entry PF00579 tRNA-synt_1b, FT tRNA synthetases class I (W and Y) and Prosite match to FT PS00178 Aminoacyl-transfer RNA synthetases class-I FT signature." FT /db_xref="GOA:Q9KZA7" FT /db_xref="HSSP:1MAU" FT /db_xref="InterPro:IPR002306" FT /db_xref="UniProtKB/Swiss-Prot:Q9KZA7" FT /protein_id="CAB89058.1" FT /translation="MSMANERPRVLSGIQPTSGSFHLGNYLGAVRQWVDMQDTHDAFYM FT VVDLHAITVPQDPKELRENTRVAAAQLLAAGLDPDRCTLFVQSHVPEHAQLGWLMNCIT FT GFGEASRMTQFKDKSAKQGNDRTTVGLFTYPMLMVADILLYQADQVPVGEDQRQHLELT FT RDLADRFNQTYGDAFTVPTAYILKETAKIYDLQDPTAKMSKSAATPKGLINLLDEPKAT FT AKKVKSAVTDTDTVVRFDRETKPGVSNLLTIYSTLTGAEIAELERKYEGKGYGALKTDL FT ADVVVEFVTPFRERTRQYLDDPETLDAILAKGAEKARSVAAETLARAYDEVGFLPAKH" FT misc_feature 193596..194270 FT /note="Pfam match to entry PF00579 tRNA-synt_1b, tRNA FT synthetases class I (W and Y), score 298.30, E-value FT 9.4e-86" FT misc_feature 193614..193646 FT /note="PS00178 Aminoacyl-transfer RNA synthetases class-I FT signature" FT RBS 194755..194759 FT CDS 194765..195343 FT /transl_table=11 FT /gene="SCO4840" FT /gene_synonym="SC5G8.08" FT /product="putative secreted protein" FT /note="SC5G8.08, possible secreted protein, len: 339aa; FT N-terminal similar to many eg. TR:Q45633 (EMBL:L13418) FT maltose permease from Bacillus stearothermophilus (314 aa) FT fasta scores; opt: 155, z-score: 191.9, E(): 0.0031, 31.5% FT identity in 127 aa overlap. Contains a possible cleavable FT N-terminal signal sequence." FT /db_xref="GOA:Q9KZA6" FT /db_xref="InterPro:IPR014051" FT /db_xref="UniProtKB/TrEMBL:Q9KZA6" FT /protein_id="CAB89059.1" FT /translation="MGTVTIGVSIAVPEPHGSKLQQLRAGFGDAAAHGIPTHVTLLPPT FT EVDGAALSAVEAHLAEVAARGRPFPMRLSGTGTFRPLSPVVFVQVVEGAAACSWLQKRV FT RDASGPVPRELQFPYHPHVTVAHGIEEAAMDRAYEELSDYEAQWPCTGFALYEQGADAV FT WRKLREFPFGSATVPPQAGRVETGSLPTR" FT CDS complement(195426..196196) FT /transl_table=11 FT /gene="SCO4841" FT /gene_synonym="SC5G8.09c" FT /product="putative short-chain dehydrogenase" FT /note="SC5G8.09c, possible short-chain dehydrogenase, len: FT 256aa; similar to many proposed oxidoreductases eg. similar FT to many eg. SW:P43168 (YMP3_STRCO) hypothetical FT oxidoreductase from Streptomyces coelicolor (251 aa) fasta FT scores; opt: 1120, z-score: 1262.0, E(): 0, 73.6% identity FT in 250 aa overlap. Contains Pfam match to entry PF00106 FT adh_short, short chain dehydrogenase and Prosite match to FT PS00061 Short-chain dehydrogenases/reductases family FT signature." FT /db_xref="GOA:Q9KZA5" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9KZA5" FT /protein_id="CAB89060.1" FT /translation="MSGAVVKDAFGLPQSLLVLGGTSEIALATVRRLVARRTRTVWLAG FT RPSPALDAAAGQLRGLGAEVRTVAFDALDPEGHEAALGKVFAEGDIDLVLLAFGILGDQ FT AHDEREPLNAVRVAQTNYTGAVSAGLVAARSLQAQGHGSLVVLSSVAGERARRANFIYG FT SSKAGLDTFAQGLGDALHGTGVHVMVVRPGFVRSRMTEGMAEAPLATTPEAVATAIELG FT LRRRSETVWVPGALRVVMSAVRHLPRAVFRRLPV" FT misc_feature complement(195603..196157) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 113.20, E-value 5e-30" FT misc_feature complement(195666..195752) FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT CDS complement(196216..197589) FT /transl_table=11 FT /gene="SCO4842" FT /gene_synonym="SC5G8.10c" FT /product="putative oxidoreductase" FT /note="SC5G8.10c, possible oxidoreductase, len: 457aa; FT similar to many of undefined function eg. SW:P43167 FT (YMP4_STRCO) hypothetical protein from Streptomyces FT coelicolor (367 aa)fasta scores; opt: 1349, z-score: FT 1513.9, E(): 0, 58.1% identity in 375 aa overlap. Contains FT Pfam match to entry PF01565 FAD_binding_4, FAD binding FT domain." FT /db_xref="GOA:Q9KZA4" FT /db_xref="InterPro:IPR006094" FT /db_xref="UniProtKB/TrEMBL:Q9KZA4" FT /protein_id="CAB89061.1" FT /translation="MSADTVPDADWGTVTGWGRTAPTAALLVRPRTYEEAAVAVRDCGA FT RGGIARGLGRAYGDAAQNAGGAVLDMTALDRVHAVDVAGGTVLCDAGVSLHRLMEVLLP FT LGWFVPVTPGTRYVTVGGAIGADIHGKNHHVSGSFTRHVLSLELLTADGRVRTVAPGTP FT LFDATAGGMGLTGVILTATLRLQPVETALMSVDTERAGDLDDLMARLTATDHRYRYSVA FT WIDLLARGRATGRAVLTRGDHAPLDALPARSRARHAPLAFRTSRLPATPDFLPGGLLSR FT TTVGLFNEVWYRKAPRESRGRLQRIATFFHPLDGVPHWNRVYGRGGFVQYQFVVGHGRE FT EALRRIVRRISARRCPSFLAVLKRFGAADPGWLSFPVPGWTLALDIPAGLPGLGAFLDE FT LDEEVADAGGRVYLAKDSRLRPELLAAMYPRLDDFRALRAELDPRGVFVSDLARRLAL" FT misc_feature complement(197050..197589) FT /note="Pfam match to entry PF01565 FAD_binding_4, FAD FT binding domain, score 6.00, E-value 1.2e-06" FT misc_feature 197668..197673 FT /note="Cleavage site for AseI restriction endonuclease FT AT*TAAT." FT misc_feature complement(197668..197673) FT /note="Cleavage site for AseI restriction endonuclease FT AT*TAAT." FT CDS 197732..198241 FT /transl_table=11 FT /gene="SCO4843" FT /gene_synonym="SC5G8.11" FT /product="putative integral membrane protein" FT /note="SC5G8.11, possible integral membrane protein, len: FT 169aa; similar to many of undefined function eg. TR:O53584 FT (EMBL:AL022076) hypothetical protein from Mycobacterium FT tuberculosis (165 aa) fasta scores; opt: 324, z-score: FT 386.8, E(): 4.3e-14, 41.5% identity in 159 aa overlap. FT Contains Pfam match to entry PF01569 PAP2, PAP2 superfamily FT and possible membrane-spanning hydrophobic regions." FT /db_xref="GOA:Q9KZA3" FT /db_xref="InterPro:IPR016118" FT /db_xref="UniProtKB/TrEMBL:Q9KZA3" FT /protein_id="CAB89062.1" FT /translation="MDDLDDMDHRIVSALRARGTDPRVAGAARALSWAGEHGALWLAAG FT LTAAAVDAPRRTAWLRGTALTAGAHVVSMGVKRVVRRPRPAHVVPLVRTAGRHSFPSSH FT ATSAAAAAVVFGTLGVRAAWPLAAAVCASRLVVGVHYPSDVAAGAALGALTARLGADWM FT RGGTRD" FT misc_feature 197837..198235 FT /note="Pfam match to entry PF01569 PAP2, PAP2 superfamily, FT score 41.10, E-value 2.5e-08" FT RBS 198224..198228 FT CDS 198234..199202 FT /transl_table=11 FT /gene="SCO4844" FT /gene_synonym="SC5G8.12" FT /product="putative integral membrane protein" FT /note="SC5G8.12, possible integral membrane protein, len: FT 322aa; similar to TR:O53583 (EMBL:AL022076) hypothetical FT protein from Mycobacterium tuberculosis (302 aa) fasta FT scores; opt: 937, z-score: 1058.4, E(): 0, 51.4% identity FT in 292 aa overlap. Contains possible membrane-spanning FT hydrophobic regions" FT /db_xref="GOA:Q9KZA2" FT /db_xref="InterPro:IPR000537" FT /db_xref="UniProtKB/TrEMBL:Q9KZA2" FT /protein_id="CAB89063.1" FT /translation="MTDTAVTDTAVLRQRAPEQQREPDPPRRARRVPAGLLRTARPRQW FT VKNVLVVAAPAAAGELFSAPAPARLALVFVLFTACAAAVYLVNDARDAEADRAHPVKRH FT RPVAAGDVPVPLAYAAGGALGVLAPVLAAWLCPAPVAVLLTAYLAMQLAYCVSLKHVLV FT VDLAVVTTGFLMRAMIGGLALGIPLSRWFLITTGFGALFMVAAKRYSEAVQMAGKDGAT FT RALLTEYTTGYLRFVWQLAAGVAVLGYCLWAMEEGGVPHTSVLPWRQLSVIPFVLAVLR FT YAVFADRGTAGEPEDVVLRDRALALIGVVWLAMYGLAVANW" FT RBS 199187..199191 FT CDS 199196..199669 FT /transl_table=11 FT /gene="SCO4845" FT /gene_synonym="SC5G8.13" FT /product="putative integral membrane protein" FT /note="SC5G8.13, possible integral membrane protein, len: FT 157aa; similar to many eg. SW:P72055 (Y1I9_MYCTU) FT hypothetical protein from Mycobacterium tuberculosis (121 FT aa) fasta scores; opt: 139, z-score: 176.2, E(): 0.023, FT 31.7% identity in 126 aa overlap. Contains possible FT membrane-spanning hydrophobic regions." FT /db_xref="GOA:Q9KZA1" FT /db_xref="InterPro:IPR007267" FT /db_xref="UniProtKB/TrEMBL:Q9KZA1" FT /protein_id="CAB89064.1" FT /translation="MVAGRRELLGFASAGLLAYAVDLGLFTCLRGPAGLDPLTAKALSF FT VAGCSVAYAGNALGTYRHLGRPRGLRPCAVFFAVNAAGAAVQLLCLIVSHYGLGLTSQR FT ADTVSGAGVGMILGTILRFWGTRTLVFRSAAGSGGPSGSWNATSGGRVGSWTG" FT CDS 199624..200589 FT /transl_table=11 FT /gene="SCO4846" FT /gene_synonym="SC5G8.14" FT /product="putative integral membrane protein" FT /note="SC5G8.14, possible integral membrane protein, len: FT 321aa; weakly similar to many eg. SW:P45417 (YHJD_ERWCH) FT hypothetical protein from Erwinia chrysanthemi (328 aa) FT fasta scores; opt: 305, z-score: 344.6, E(): 9.7e-12, FT 29.7% identity in 283 aa overlap. Contains possible FT membrane-spanning hydrophobic regions." FT /db_xref="GOA:Q9KZA0" FT /db_xref="InterPro:IPR004664" FT /db_xref="UniProtKB/TrEMBL:Q9KZA0" FT /protein_id="CAB89065.1" FT /translation="MERDERGQGRIMDWLKKLPVAGPWIARLMTTHAWRSYERLDRVKW FT SRLAAAMTFTSFVALFPLLSLAAAVAAATLNKQQQDKLQDKLAEQIPGISDQLNIQGLV FT DNAGTVGVISALLLLFTGMGWIEATRGCLRAVWELPDEDENPVLHRAKDAGVLVGLGGA FT LLITVGISTVASALVGWIIRTIGLAQGGVGGVLLYVAAFAVAVLADFLLLLYVLTLLPG FT VQPERRRLVVAALIGAVGFELLKLLLSGYIQGVAAKSMYGAFGVPVALLLWINFTAKLV FT LFCASWTATGSKAQELGEPGDADVTDGSGGGPGPAAATSG" FT CDS complement(200537..201811) FT /transl_table=11 FT /gene="SCO4847" FT /gene_synonym="SC5G8.15c" FT /product="putative D-alanyl-D-alanine carboxypeptidase" FT /note="SC5G8.15c, possible D-alanyl-D-alanine FT carboxypeptidase, len: 455 aa; similar to many e.g. FT TR:O53380 (EMBL:AL021841) proposed penicillin-binding FT protein from Mycobacterium tuberculosis (405 aa) fasta FT scores; opt: 392, z-score: 369.1, E(): 4.2e-13, 31.7% FT identity in 439 aa overlap. Contains Pfam match to entry FT PF00768 Peptidase_S11, D-alanyl-D-alanine carboxypeptidase. FT Position of translational start uncertain." FT /db_xref="GOA:Q9KZ99" FT /db_xref="HSSP:1NJ4" FT /db_xref="InterPro:IPR001967" FT /db_xref="UniProtKB/TrEMBL:Q9KZ99" FT /protein_id="CAB89066.1" FT /translation="MPAPKKALRRSLTVTSAALTALALLSPAALAAPSPSTSPSATPPA FT SMSGVGGARLGKPGTQVDLAGGAPVLPKDLTARSWIVADAESGDVLAAHNAHWELAPAS FT TLKMLFADTLLPKWPKTTKRKVQVSDLAGIGSGSSMVGIKEEETYTVHDLWLGVFLRSG FT NDAVHVLSAMNDGVEKTVADMNAHAKELQAGDTTVVSPDGYDMPGQVSSAYDLTLFARS FT GLQKKDFREYASTVRAKFPGETKKDKKGKTSREPFEIQNTNRLLAGDADVEVYPGIAGV FT KNGYTTNAGNTFTGVAEQGGKVLLVTVMHPAEDKHNEVYKETARLFDWGFRAAGKVRPV FT GELVRPRSATAASPSAEASGEAGGTGKGGAGTKPVAGAAAGDGAGGAGVAAGIAAGVLA FT LLAGGAFLINRKWPLPDLVRRRTRP" FT misc_feature complement(200804..201619) FT /note="Pfam match to entry PF00768 Peptidase_S11, FT D-alanyl-D-alanine carboxypeptidase, score 129.70, E-value FT 5.4e-35" FT misc_feature complement(201845..202024) FT /note="attB, attachment site for bacteriophage phiBT1 (M. FT Smith, Uni. of Nottingham, Nottingham, UK)." FT CDS 201903..202142 FT /transl_table=11 FT /gene="SCO4848" FT /gene_synonym="SC5G8.16" FT /product="putative integral membrane protein" FT /note="SC5G8.16, possible integral membrane protein, len: FT 79aa; contains possible membrane-spanning hydrophobic FT regions. Position of translational start uncertain, FT possible alternative start at 13619." FT /db_xref="UniProtKB/TrEMBL:Q9KZ98" FT /protein_id="CAB89067.1" FT /translation="MKLSRPVSWFLLAFGVWSWIIWITFVKNLVKDGSGLAFEDGDPTA FT YFWVHLLLAIVSFVLGTVVGVIGLRGVRALRRTS" FT RBS 202182..202188 FT CDS 202197..203507 FT /transl_table=11 FT /gene="SCO4849" FT /gene_synonym="SC5G8.17" FT /product="putative integral membrane protein" FT /note="SC5G8.17, possible integral membrane protein, len: FT 436 aa; N-terminal region contains possible FT membrane-spanning hydrophobic regions while the remainder FT is similar to many hypothetical proteins e.g. TR:Q9ZM43 FT (EMBL:AE001473) putative from Helicobacter pylori J99 (370 FT aa) fasta scores; opt: 596, z-score: 590.7, E(): 1.9e-25, FT 37.4% identity in 273 aa overlap" FT /db_xref="GOA:Q9KZ97" FT /db_xref="InterPro:IPR004843" FT /db_xref="UniProtKB/TrEMBL:Q9KZ97" FT /protein_id="CAB89068.1" FT /translation="MVVVFVLVALLMVGVLVTANWYVWRRLFRDTTRAPGPVRRIGAAV FT IAGGWLLAVGALVAERAGAPFWLQRVLAWPGFLWLALSIYLLLAVLAGEVVRPLLRRFL FT ERRAAARRTAGAEPSVTPAADTSRIPAGTAPPKTPEAPETPEAPGTEALAAQGSPLAVP FT SRRLFVSRVVAGAAAAAAVGTVGYGTYGVLSGPKVKRVTVPLAKLPRAAHGFRIAVVSD FT IHLGPVLGRGFAQQVVDTINSTQPDLIAVVGDLVDGSVKDLGPAAAPLARLTARHGAYF FT VTGNHEYFSGAEQWVAEVRRLGLLPLENARTELPHFDLAGVNDVAGEDEGQGPDYDRAL FT GDRDRSRACVLLAHQPVQIHDAVDHGVDLQLSGHTHGGQLWPGNLIAGAANPTLAGLER FT YGDTQLYVSRGAGAWGPPTRVGAPSDITVIELASRQA" FT CDS complement(203498..204253) FT /transl_table=11 FT /gene="SCO4850" FT /gene_synonym="SC5G8.18c" FT /product="putative tetR-family transcriptional regulator" FT /note="SC5G8.18c, possible tetR-family transcriptional FT regulator, len: 251 aa; N-terminal region similar to many FT e.g. TR:CAB53315 (EMBL:AL109974) putative tetR-family FT transcriptional regulator from Streptomyces coelicolor (203 FT aa) fasta scores; opt: 190, z-score: 242.1, E(): 5e-06, FT 35.0% identity in 103 aa overlap. Contains Pfam match to FT entry PF00440 tetR, Bacterial regulatory proteins, tetR FT family and helix-turn-helix motif 40..61 aa" FT /db_xref="GOA:Q9KZ96" FT /db_xref="InterPro:IPR012287" FT /db_xref="PDB:3C07" FT /db_xref="UniProtKB/TrEMBL:Q9KZ96" FT /protein_id="CAB89069.1" FT /translation="MPATNDGPDDGAHLSKSEQTRALILETAMRLFQERGYDRTTMRAI FT AQEAGVSVGNAYYYFAGKEHLIQGFYDRIAAEHRAAVREVLARETDLEARLAGVLKVWL FT DIATPYHEFAVQFFKNAADPDSPLSPFSPESEHARVEAIGIHRAVLAGAKTKVPEELRD FT ILPELMWLSQMGLVLYWIFDRTEGRERSYRLAERGARLTARGVVLARFRVLRPLVREVH FT ELFTDFLPGMTKVMPDPAKKPTRDAGPQA" FT misc_feature complement(204044..204184) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 52.90, E-value FT 6.1e-13" FT CDS complement(204265..204753) FT /transl_table=11 FT /gene="SCO4851" FT /gene_synonym="SC5G8.19c" FT /product="hypothetical protein" FT /note="SC5G8.19c, unknown, len: 162aa;" FT /db_xref="InterPro:IPR007263" FT /db_xref="UniProtKB/TrEMBL:Q9KZ95" FT /protein_id="CAB89070.1" FT /translation="MAPAPGPTAGAPVRRLTVLYDAECSLCTHVRDWLLRQPRLVPLEL FT VPAASEEARRRFPGLDHGATLDEVTAVGDAGQVYRGAAAWVVVLWALRGYRRLAHRLST FT PKGALLARGAVLAAAKWRAGQRSAGGYAYRRADGWVYEPRLGWIYAGPGCDDGTCATG" FT CDS complement(204758..205165) FT /transl_table=11 FT /gene="SCO4852" FT /gene_synonym="SC5G8.20c" FT /product="putative integral membrane protein" FT /note="SC5G8.20c, possible integral membrane protein, len: FT 135 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9KZ94" FT /protein_id="CAB89071.1" FT /translation="MDRTVIAYVIYLAVSIGLTVWVARTLSRNGRVFLSDVLHGNEKLA FT DAVNHLLVVGFYLVNLGFVALYLSDDETITNARGIFEALSTKLGVVLLVLGVMHLGNVY FT VLNKIRRRGLMEREQVPPVPPQGWVAPTAGA" FT RBS complement(204763..204766) FT RBS complement(205169..205173) FT CDS complement(205251..205661) FT /transl_table=11 FT /gene="SCO4853" FT /gene_synonym="SC5G8.21c" FT /product="hypothetical protein" FT /note="SC5G8.21c, unknown, len: 136 aa; weakly similar to FT other hypothetical proteins eg. TR:AAF12497 (EMBL:AE001863) FT from Deinococcus radiodurans (117 aa) fasta scores; opt: FT 109, z-score: 149.3, E(): 0.74, 26.1% identity in 111 aa FT overlap." FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/TrEMBL:Q9KZ93" FT /protein_id="CAB89072.1" FT /translation="MSDDESYELLGFDNVLLPVGDLAEAVGFYERAGFPVAYRLDEAGI FT ALLKVGVETPGLLLRAEEEFGRQPPMWPSARVWLEVTDARAAARELREAGVPPLDEPFP FT VATGWTVEFADPWGNVIGLTDYSKRPELGRRP" FT CDS complement(205703..206323) FT /transl_table=11 FT /gene="SCO4854" FT /gene_synonym="SC5G8.22c" FT /product="putative integral membrane protein" FT /note="SC5G8.22c, possible integral membrane protein, len: FT 206aa; weakly similar to many eg. TR:P72920 (EMBL:D90901) FT hypothetical protein from Synechocystis sp. (strain PCC FT 6803) (181 aa) fasta scores; opt: 183, z-score: 238.4, FT E(): 8e-06, 28.8% identity in 146 aa overlap. Contains FT possible membrane-spanning hydrophobic regions." FT /db_xref="InterPro:IPR008538" FT /db_xref="UniProtKB/TrEMBL:Q9KZ92" FT /protein_id="CAB89073.1" FT /translation="MSAASVELPHGDLPLIAEANRIMERNPGYRVEIIGGQLVVTPPPD FT GPHAVVLTDLILPFAAAGLHGSESKVVQGIGLWLPMDAEDYAIPDLAVVDADVDDHLVE FT NNCYDPVCFRLVLEVTSSNWRNDLKAKVTAYAAAMVPVYVIVDRKHQRLHVLTDPDCAD FT YSTHRVHSPGETVTLPDSLGAEVTLDVGEILAAGRPKSAPGEG" FT RBS complement(206330..206335) FT CDS complement(206489..207262) FT /transl_table=11 FT /gene="SCO4855" FT /gene_synonym="dhsB" FT /gene_synonym="SC5G8.23c" FT /product="putative succinate dehydrogenase iron-sulfur FT subunit" FT /note="SC5G8.23c, dhsB, probable succinate dehydrogenase FT iron-sulfur subunit, len: 257aa; strongly similar to many FT eg. SW:P07014 (DHSB_ECOLI) succinate dehydrogenase FT iron-sulfur protein from Escherichia coli (238 aa) fasta FT scores; opt: 729, z-score: 839.1, E(): 0, 44.3% identity FT in 237 aa overlap. Contains Pfam match to entry PF00111 FT fer2, 2Fe-2S iron-sulfur cluster binding domains, Pfam FT match to entry PF00037 fer4, 4Fe-4S ferredoxins and related FT iron-sulfur cluster binding domains and Prosite match to FT PS00198 4Fe-4S ferredoxins, iron-sulfur binding region FT signature." FT /db_xref="GOA:Q9KZ91" FT /db_xref="HSSP:1NEK" FT /db_xref="InterPro:IPR004489" FT /db_xref="UniProtKB/TrEMBL:Q9KZ91" FT /protein_id="CAB89074.1" FT /translation="MATPVMEKSDQAPEPGFADSPYITVTFRVRRFNPEVAAEATWEDF FT QLEIDPKERVLDALHKIKWELDGSLTFRRSCAHGICGSDAMRINGKNRLACKTLIKDLS FT PEKPITVEPIKGLTVLKDLVVDMEPFFQAYRDVMPFLITKDTNEPTRERLQTAEDRERF FT DDTTKCILCAACTSSCPVFWNDGQYFGPAAIVNAHRFIFDSRDEAGEQRLEILNDRDGV FT WRCRTTFNCTDACPRGIEVTKAIAEVKRALITRRF" FT misc_feature complement(206534..206779) FT /note="Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins FT and related iron-sulfur cluster binding domains., score FT 32.10, E-value 3.9e-08" FT misc_feature complement(206723..206758) FT /note="PS00198 4Fe-4S ferredoxins, iron-sulfur binding FT region signature" FT misc_feature complement(206957..207151) FT /note="Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur FT cluster binding domains, score 12.50, E-value 0.084" FT CDS complement(207262..209016) FT /transl_table=11 FT /gene="SCO4856" FT /gene_synonym="dhsA" FT /gene_synonym="SC5G8.24c" FT /product="putative succinate dehydrogenase flavoprotein FT subunit" FT /note="SC5G8.24c, dhsA, probable succinate dehydrogenase FT flavoprotein subunit, len: 584aa; strongly similar to many FT eg. SW:P10444 (DHSA_ECOLI) succinate dehydrogenase FT flavoprotein subunit from Escherichia coli (588 aa) fasta FT scores; opt: 1842, z-score: 2076.6, E(): 0, 48.4% identity FT in 591 aa overlap. Contains Pfam match to entry PF00890 FT FAD_binding_2, FAD binding domain and Prosite match to FT PS00504 Fumarate reductase / succinate dehydrogenase FT FAD-binding site." FT /db_xref="GOA:Q9KZ90" FT /db_xref="HSSP:1NEK" FT /db_xref="InterPro:IPR011281" FT /db_xref="UniProtKB/TrEMBL:Q9KZ90" FT /protein_id="CAB89075.1" FT /translation="MKVHKYDTVIVGAGGAGMRAAIESTKRSRTAVLTKLYPTRSHTGA FT AQGGMAAALANVEEDNWEWHTFDTVKGGDYLVDQDAAEILAKEAIDSVLDLEKMGLPFN FT RTPDGTIDQRRFGGHSRNHGEAPVRRSCYAADRTGHMILQTLYQNCVKEGVEFFNEFYV FT LDQLITEVDGVKKSAGVVAYELATGEIHVFQAKSVIYASGGTGKFFKVTSNAHTLTGDG FT QAAVYRRGLPLEDMEFFQFHPTGIWRMGILLTEGARGEGGILRNKDGERFMEKYAPVMK FT DLASRDVVSRSIYTEIREGRGCGPEGDHVYLDLTHLPPEQLDAKLPDITEFARTYLGIE FT PYTDPIPIQPTAHYAMGGIPTNVEGEVLADNTTVVPGLYAAGEVACVSVHGANRLGTNS FT LLDINVFGRRAGIAAAEYAQKADFVELPEDPETLVVEQIERLRSSTGTERVATIRRELQ FT ECMDANVMVFRTEQTIKTAVEKIAELRARYKNVSIQDKGRRFNTDLLEAVELGNLLDLA FT EVMAVSALARKESRGGHYREDFPNRDDVNFMRHTMAYREVGDDGAESIRLDYKPVVQTR FT YQPMERKY" FT RBS complement(207274..207277) FT misc_feature complement(207715..208704) FT /note="Pfam match to entry PF00890 FAD_binding_2, FAD FT binding domain, score 616.20, E-value 1.9e-181" FT misc_feature complement(208870..208899) FT /note="PS00504 Fumarate reductase / succinate dehydrogenase FT FAD-binding site" FT RBS complement(209028..209031) FT CDS complement(209036..209518) FT /transl_table=11 FT /gene="SCO4857" FT /gene_synonym="SC5G8.25c" FT /product="putative succinate dehydrogenase membrane FT subunit" FT /note="SC5G8.25c, dhsD, possible succinate dehydrogenase FT membrane subunit, len: 160 aa; similar to TR:O53369 FT (EMBL:AL021841) putative membrane anchor of succinate FT dehydrogenase from Mycobacterium tuberculosis (144 aa) FT fasta scores; opt: 553, z-score: 702.9, E(): 1.1e-31, 58.9% FT identity in 141 aa overlap. Also weakly similar to FT SW:P10445 (DHSD_ECOLI) succinate dehydrogenase hydrophobic FT membrane anchor protein from Escherichia coli (115 aa) FT fasta scores; opt: 126, z-score: 172.2, E(): 0.039, 23.5% FT identity in 115 aa overlap. Contains possible FT membrane-spanning hydrophobic regions and Pfam match to FT entry PF01127 Sdh_cyt, Succinate dehydrogenase cytochrome b FT subunit." FT /db_xref="GOA:Q9KZ89" FT /db_xref="InterPro:IPR000701" FT /db_xref="UniProtKB/TrEMBL:Q9KZ89" FT /protein_id="CAB89076.1" FT /translation="MSTTESPASGIGPIEGASLYSADNPAPLIEAPRARTKKSPKSTRG FT NFEMAAWLFMRLSGVVLVVLVLGHLLIQLVLDGGVSKIGFAFVAGRWASPFWQVWDLLM FT LWLAMLHGANGLRTVINDYAERPNTRLWLKGLLYTATVFTILLGTLVIFTFDPNIR" FT misc_feature complement(209069..209410) FT /note="Pfam match to entry PF01127 Sdh_cyt, Succinate FT dehydrogenase cytochrome b subunit, score -44.90, E-value FT 1.1" FT CDS complement(209524..209904) FT /transl_table=11 FT /gene="SCO4858" FT /gene_synonym="SC5G8.26c" FT /product="putative succinate dehydrogenase membrane FT subunit" FT /note="SC5G8.26c, dhsC, possible succinate dehydrogenase FT membrane subunit, len: 126aa; similar to many eg. TR:O53368 FT (EMBL:AL021841) putative membrane anchor of succinate FT dehydrogenase from Mycobacterium tuberculosis (112 aa) FT fasta scores; opt: 484, z-score: 649.2, E(): 1e-28, 65.7% FT identity in 99 aa overlap. Also wealky similar to SW:P10446 FT (DHSC_ECOLI) succinate dehydrogenase cytochrome b-556 FT subunit from Escherichia coli (129 aa) fasta scores; opt: FT 121, z-score: 173.9, E(): 0.031, 29.6% identity in 71 aa FT overlap. Contains Pfam match to entry PF01127 Sdh_cyt, FT Succinate dehydrogenase cytochrome b subunit." FT /db_xref="GOA:Q9KZ88" FT /db_xref="InterPro:IPR014314" FT /db_xref="UniProtKB/TrEMBL:Q9KZ88" FT /protein_id="CAB89077.1" FT /translation="MPAGTLYRGREGMWSWVAHRVTGVLIFFFLFVHVLDTALVRVSPE FT AYDTVVATYKTPIVALLEYGLVAAILFHALNGLRVIAVDFWVKGARYQKQMLWTVVALW FT VVLMLGAIYPVLGHAARELFGS" FT RBS complement(209528..209531) FT misc_feature complement(209575..209886) FT /note="Pfam match to entry PF01127 Sdh_cyt, Succinate FT dehydrogenase cytochrome b subunit, score -10.40, E-value FT 0.0019" FT RBS complement(209913..209917) FT CDS complement(210086..210637) FT /transl_table=11 FT /gene="SCO4859" FT /gene_synonym="SC5G8.27c" FT /product="hypothetical protein" FT /note="SC5G8.27c, unknown, len: 183 aa; similar to FT TR:Q9Z593 (EMBL:AL035478) hypothetical protein from FT Streptomyces coelicolor (191 aa) fasta scores; opt: 164, FT z-score: 195.7, E(): 0.0019, 32.6% identity in 187 aa FT overlap." FT /db_xref="InterPro:IPR018020" FT /db_xref="UniProtKB/TrEMBL:Q9KZ87" FT /protein_id="CAB89078.1" FT /translation="MQTRATPAPAAPLERFNAAPAEEAAGTLLACLHSRAWADRLVAHR FT PYPDLPALLAAADEAAYDLSSDDLSEALAAETLPALPEDTYAAAHTALSAAHAAYESRF FT GHVFVISLDGLSPEETLNHVLAAIRSRLANDPDEERLVASEELRRLAGGRVRRLLGARG FT TARPATDDPHPANHTKPPPP" FT RBS complement(210652..210655) FT RBS 210906..210909 FT CDS 210919..212493 FT /transl_table=11 FT /gene="SCO4860" FT /gene_synonym="SCK20.01" FT /gene_synonym="SC5G8.28" FT /product="putative secreted hydrolase" FT /note="SCK20.01, probable secreted hydrolase (fragment), FT len: >465 aa; similar to C-terminal region of SW:HEXA_DICDI FT (EMBL:J04065) Dictyostelium discoideum beta-hexosaminidase FT A precursor (EC 3.2.1.52) NagA, 532 aa; fasta scores: opt: FT 343 z-score: 387.7 E(): 4.6e-14; 25.4% identity in 393 aa FT overlap. Contains Pfam match to entry PF00728 FT Glyco_hydro_20, Glycosyl hydrolase family 20" FT /note="SC5G8.28, partial CDS, possible secreted protein, FT len: >94aa; contains a possible cleavable N-terminal signal FT sequence." FT /db_xref="GOA:Q8CJS6" FT /db_xref="HSSP:1NOW" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:Q8CJS6" FT /protein_id="CAD55218.1" FT /translation="MIAGAVVAALGVGAGLWATDGDGGGDGDREGSAARSSTGEAAAPS FT PSRSYPLSKEPRTIPAVREHTAARGPGWQPEKGNRVVVADSGLADEGKQIAGDLGMTYA FT GEKDDERAGDLLLDVKAAKGANPESYTMTVRDGRVTVTGPAEAGVYYGTRTLKQAVDGG FT GTAPEGVVKDEPAKPKRGFSLDIARKHYSADWIKDRIRELGDLKFNELGLHFSDDQAFR FT IESDSHPEIVSDEHLTKAEMKEIIDLAASRHITVVPEIDSPGHLGAVIAAHPDLQLRNA FT QGTATRGAIDISKPEAAKIVDDLLNEYADLFPGSQFHLGADEYQALVVPNPEASYPTLA FT AAARKAYGSGGTVADLTTGWLNGRAKTVMAHDRTPRAWNDGFFKDTSVEPLKDIKVAYW FT TGKEIGARPPAEYLGEGRQVLNYNDEFLYYVLGQPQTFVYPTGERIYEQWTPRVLRGTT FT AVDAKYDDQILGGSFAVWGDFPNAQTQAQVAEGIRLPLAATVQKLWDPGKPELSWTDFA FT ALANRLD" FT misc_feature 211300..211887 FT /note="Pfam match to entry PF00728 Glyco_hydro_20, Glycosyl FT hydrolase family 20, score 71.80, E-value 1.9e-18" FT CDS 212612..213157 FT /transl_table=11 FT /gene="SCO4861" FT /gene_synonym="SCK20.02" FT /product="hypothetical protein SCK20.02" FT /note="SCK20.02, unknown, len: 181 aa" FT /db_xref="UniProtKB/TrEMBL:Q9EWE6" FT /protein_id="CAC17649.1" FT /translation="MGYWGYFVVGRAERPLAELEALSGAGDMTLRQSAPDGWQVWEFPG FT GDGDVGNMNDLAGQTGAPALFGYVMDSDCVVVEAAAPESGAWTTCLARTAMAGYLGAER FT DGLTLEDYFLEPRDAAERAVAWAAEAGCAASPAELAGVLSDDPAAEPDAGGDRVLAPGP FT VAENLFFRFLDRLGVVPL" FT RBS 213234..213238 FT CDS 213245..213814 FT /transl_table=11 FT /gene="SCO4862" FT /gene_synonym="SCK20.03" FT /product="hypothetical protein SCK20.03" FT /note="SCK20.03, unknown, len: 189 aa" FT /db_xref="UniProtKB/TrEMBL:Q9EWE5" FT /protein_id="CAC17650.1" FT /translation="MSLVELIARADTRGLAASGLACLDRCVPLLDGDDEALRPLWATLA FT DASGDASGPDWAEALAQVRDKLAGPGATGEDEAAVLARRMLAAAPAECSGPVLRTWADA FT CSVASLRIHRLLAPAAGAAPEADVPRDAGTEGLPPLVAAELRRQAAVLELLAGHGAAGV FT RPALEVSTEGRRVLRAVVSRRARGRG" FT CDS 213982..214404 FT /transl_table=11 FT /gene="SCO4863" FT /gene_synonym="SCK20.04" FT /product="hypothetical protein SCK20.04" FT /note="SCK20.04, unknown, len: 140 aa" FT /db_xref="UniProtKB/TrEMBL:Q9EWE4" FT /protein_id="CAC17651.1" FT /translation="MTSGLTSGWTSGTTSPQQPRPSAAARPVRWAADAVATMREGARLR FT LDYSAQSLWRVDRMIDGIRGEEAPYAAVETALRGLGAYAGEVIVRQSGGEWWTTGGDHW FT VRTPDGRLWDPIDEARRCFAGDGSLRLLCRDATAPR" FT CDS 214471..215148 FT /transl_table=11 FT /gene="SCO4864" FT /gene_synonym="SCK20.05" FT /product="putative ECF sigma factor" FT /note="SCK20.05, possible ECF sigma factor, len: 225 aa; FT similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces FT coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 296 FT z-score: 342.7 E(): 1.5e-11; 34.0% identity in 212 aa FT overlap and to Streptomyces coelicolor putative ECF sigma FT factor SCK20.07, 220 aa; fasta scores: opt: 671 z-score: FT 656.4 E(): 6.9e-31; 59.5% identity in 185 aa overlap. FT Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 FT factor (ECF subfamily)" FT /db_xref="GOA:Q9EWE3" FT /db_xref="InterPro:IPR007627" FT /db_xref="UniProtKB/TrEMBL:Q9EWE3" FT /protein_id="CAC17652.1" FT /translation="MTLGGAHRSARRTRYGRGRFLGQRGEPRRVQAYDGELGAAVARAQ FT QGDEAAFAVAYRLVQPGLLGYVRGLVGEDAEDVAADAWLEIARDLRRFKGDGAGFRGWT FT ATIARHRALDHLRRQKVRPRPTALEQDVLDLPGPHSTHEQVLETLSTRAALGLVAALPR FT DQAEAVLLRVVVGLDGPSAARVLGKRPGAVRTATYRGLKRLARQLGADGVTDDGPRTLG FT EST" FT misc_feature 214663..214827 FT /note="Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 FT factor (ECF subfamily), score 34.80, E-value 1.9e-06" FT RBS 215136..215139 FT CDS 215145..216065 FT /transl_table=11 FT /gene="SCO4865" FT /gene_synonym="SCK20.06" FT /product="hypothetical protein SCK20.06" FT /note="SCK20.06, unknown, len: 306 aa. High G+C content FT (82.13%)" FT /db_xref="UniProtKB/TrEMBL:Q9EWE2" FT /protein_id="CAC17653.1" FT /translation="MRGAAGGGPADRAGAEADMGARHEAGDGRDTGPRPAPGGVPGTEA FT LLAAALRAESAGTEGERRALAAFRAARDAEPARAARTRRRDDWRPRDGRHQGRTPRTAL FT SVLLASLTLGGVAYAAMGGGGSASDDGGPDRTRPPAVSDDAPARPAATPPGTTPGPGTT FT GPATTPPGASESPGTSAPPRVSTPPGPPSVGRDTEAQCRVYERLAGNGKSLDAAAWRRL FT VAAAGGAERVETYCADQLDRLGLPTGPGPSTGAGNGTGGNDAGNGGTGDTGTEGGAGGI FT LGDGGADPEAGDGGIAAQVPDLDHP" FT misc_feature 215541..215717 FT /note="High content in proline, threonine and alanine amino FT acid residues. High content in G+C (86.44%)" FT CDS 216449..217111 FT /transl_table=11 FT /gene="SCO4866" FT /gene_synonym="SCK20.07" FT /product="putative ECF sigma factor" FT /note="SCK20.07, possible ECF sigma factor, len: 220 aa; FT similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces FT coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 280 FT z-score: 329.1 E(): 8.5e-11; 31.9% identity in 182 aa FT overlap and to Streptomyces coelicolor putative ECF sigma FT factor SCK20.05, 225 aa; fasta scores: opt: 671 z-score: FT 614.8 E(): 1.4e-28; 59.5% identity in 185 aa overlap. FT Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 FT factor (ECF subfamily)" FT /db_xref="GOA:Q9EWE1" FT /db_xref="HSSP:1OR7" FT /db_xref="InterPro:IPR007627" FT /db_xref="UniProtKB/TrEMBL:Q9EWE1" FT /protein_id="CAC17654.1" FT /translation="MLGDDAELTAAVRAAQDGDETAFRTVYRAVQPRLLGYVRTLVGDP FT DAEDVASEAWLQIARDLERFDGDADRFRGWAARIARNRALDHIRMRGRRPVIGGDETEL FT TGRPAESDTAGEAMEALATGSTLSLIARLPQDQAEAVVLRVVMGLDAKSAAETLGKRPG FT AVRTAAHRGLKRLAELLGGDPESGGGLDALPPQREPHGRAVTSASVTHTRARTQKDM" FT misc_feature 216554..216721 FT /note="Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 FT factor (ECF subfamily), score 33.90, E-value 3.6e-06" FT CDS 217111..218292 FT /transl_table=11 FT /gene="SCO4867" FT /gene_synonym="SCK20.08" FT /product="putative membrane protein" FT /note="SCK20.08, possible membrane protein, len: 393 aa. FT Contains possible hydrophobic membrane spanning regions and FT 2x degenerate repeat at C-terminal region: PHHP(A/D)R" FT /db_xref="UniProtKB/TrEMBL:Q9EWE0" FT /protein_id="CAC17655.1" FT /translation="MADEQDKWLDRETAEFLLRGEPLEGADPAVRDRAERLLAALGALA FT PPVPAGEELPGEAAALAAFRKVRAEQADASAGVSAAVGHGAADRLSGAGPVRVGSRGEG FT ARRPRRGRPLRLGLAAALTVGMIGGVAAAAGTGVLPTPFDRTEPEPAATVSAAASPGRP FT LAPPSPLDGVQGGSVPGATPGAPEGGTARDGGEAQDRGADDRNPGGSDGRRSSLAASCR FT KVRAGKELDTAHRHALKEAAGGASRVGKYCGALLAGTGTGGRDDTGRATPGGPVREGEL FT RGDTGDGDGQGEKSDAGGKGGKGGKDGKDGKSDEGEGKGNGKGNGQGKDKGKGQGKGDD FT DGNGGDEDDAGIAPPRRGPHHPARPHHPDRAHGPHTSPAHRPQPQHTGAPHAA" FT misc_feature 217957..218163 FT /note="High content in glycine, aspartic and lysine amino FT acid residues" FT misc_feature 218185..218220 FT /note="2x degenerate repeat translated in SCK20.08" FT CDS complement(218535..219380) FT /transl_table=11 FT /gene="SCO4868" FT /gene_synonym="SCK20.09c" FT /product="putative lipoprotein" FT /note="SCK20.09c, possible lipoprotein, len: 281 aa; FT similar to TR:CAC14938 (EMBL:AL449216) Streptomyces FT coelicolor putative secreted protein 3SC5B7.14c, 231 aa; FT fasta scores: opt: 330 z-score: 353.2 E(): 3.9e-12; 35.3% FT identity in 218 aa overlap. Contains Pfam match to entry FT PF01471 PG_binding_1, Putative peptidoglycan binding domain FT and correctly situated match to Prosite entry PS00013 FT Prokaryotic membrane lipoprotein lipid attachment site. FT Also contains possible N-terminal region signal peptide FT sequence" FT /db_xref="GOA:Q9EWD9" FT /db_xref="InterPro:IPR005490" FT /db_xref="UniProtKB/TrEMBL:Q9EWD9" FT /protein_id="CAC17656.1" FT /translation="MRMTGMGSTGRVVAVALGAVLVAGGCTVQGTGPDGRGRAPVRIEV FT TGHPPKSTPAPDRHRPSSAPPAAPAAARVLWKRGDTGRDVRELQARLRQVEWLVDGPTG FT TYDDLTERAVSGFQGKRGLPRTGRTDTVTWQRLLGMSHEPGKWDLYLMGGQPAAAPDPR FT CTSGRVLCVSKSSRTLRWMIDGRTVSTMSVRFGSQYTPTREGVFQVYWKSRHHVSTLYD FT SAMPYAMFFSGGQAVHYSYDFAARGYAGASHGCVNVRDEAAIADLYAQVKTGDKVVVYQ FT " FT misc_feature complement(218958..219140) FT /note="Pfam match to entry PF01471 PG_binding_1, Putative FT peptidoglycan binding domain, score 25.80, E-value 0.00029" FT misc_feature complement(219303..219335) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS 219595..219599 FT CDS 219607..221211 FT /transl_table=11 FT /gene="SCO4869" FT /gene_synonym="mutA2" FT /gene_synonym="SCK20.10" FT /product="methylmalonyl CoA mutase" FT /note="SCK20.10, mutA2, methylmalonyl CoA mutase, len: 534 FT aa; highly similar to SW:MUTA_HUMAN (EMBL:M65131) Homo FT sapiens methylmalonyl CoA mutase mitochondrial precursor FT (EC 5.4.99.2) Mut, 750 aa; fasta scores: opt: 1707 z-score: FT 1912.4 E(): 0; 49.6% identity in 534 aa overlap and almost FT identical to TR:Q9L1V3 (EMBL:AL138668) Streptomyces FT coelicolor methylmalonyl CoA mutase mutA SC4A9.09, 531 aa; FT fasta scores: opt: 3319 z-score: 3721.0 E(): 0; 97.0% FT identity in 528 aa overlap. Contains Pfam match to entry FT PF01642 MM_CoA_mutase, Methylmalonyl-CoA mutase" FT /db_xref="GOA:Q9EWD8" FT /db_xref="HSSP:1REQ" FT /db_xref="InterPro:IPR006098" FT /db_xref="UniProtKB/TrEMBL:Q9EWD8" FT /protein_id="CAC17657.1" FT /translation="MLSGRHHTMTRESESGLPIEPVYGPEALADWEAAEKLGEPGKYPF FT TRGVYPSMYTGRPWTMRQYAGFGTATESNARYKQLIANGTMGLSVAFDLPTQMGHDSDA FT PIASGEVGKVGVAIDSIDDMRVLFGGIPLDKVSTSMTINAPASLLLLLYQLVAEEQGVS FT ADQLTGTIQNDVLKEYIARGTYIFPPKPSLRLIADIFKYCRAEIPKWNTISISGYHMAE FT AGASPAQEIAFTLADGIEYVRTAVAAGMDVDDFAPRLSFFFVARTTILEEVAKFRAARR FT IWARVMKEEFGAKNPKSLMLRFHTQTAGVQLTAQQPEVNLVRVAVQGLGAVLGGTQSLH FT TNSFDEAIALPTDKSARLALRTQQVLAYETDVTATVDPFAGSYVVEKMTDDVEAAALEL FT MGKVEDLGGAVNAIEHGFQKSEIERSAYRIAQETDSGERVVVGVNRYQLDEEEPYEPLR FT VDPAIEAQQADRLAALRAERDQTAVDSALAALKKAAEGEDNVLYPMKDALRARATVGEV FT CNALREVWGTYVPSDAF" FT misc_feature 219754..221208 FT /note="Pfam match to entry PF01642 MM_CoA_mutase, FT Methylmalonyl-CoA mutase, score 869.20, E-value 1.3e-257" FT CDS complement(221231..222682) FT /transl_table=11 FT /gene="SCO4870" FT /gene_synonym="SCK20.11c" FT /product="putative monooxygenase" FT /note="SCK20.11c, probable monooxygenase, len: 483 aa; FT similar to TR:P95598 (EMBL:U56415) Corynebacterium equii FT rifampin monooxygenase Iri, 479 aa; fasta scores: opt: 691 FT z-score: 714.1 E(): 3.1e-32; 35.0% identity in 488 aa FT overlap and to TR:O86481 (EMBL:AJ007932) Streptomyces FT argillaceus oxygenase MtmOII, 531 aa; fasta scores: opt: FT 590 z-score: 609.9 E(): 1.9e-26; 33.3% identity in 520 aa FT overlap. Contains Pfam match to entry PF01494 FT FAD_binding_3, FAD binding domain and match PF01360 FT Monooxygenase, Monooxygenase" FT /db_xref="GOA:Q9EWD7" FT /db_xref="HSSP:1FOH" FT /db_xref="InterPro:IPR003042" FT /db_xref="UniProtKB/TrEMBL:Q9EWD7" FT /protein_id="CAC17658.1" FT /translation="MNVTDTHVAGTDVPDTDVLIVGAGPTGLTLGVELARRGVHALVLE FT GAGELFPGSRGKGFQPRTMEVFDDLGVVDALHAVGGPYPIGMIWRNGERVGEHHMFDPA FT EPSEDSPYNRAWMVPQWRTQEILAARLAELGGRVAFRHEVVGVAQDAEGVTAHLSSGGT FT VRARYLVAADGGRSAARRALGIGMTGETVDPSPTLVADVRISGLDRDNWHVFPPGDGVD FT LLAVCPLAGTEDFQVMARFPEGADLDTSADGVRKVVAERSHIAAEDVTEVRWVSDFRPR FT AALADRFRDGRVFLAGDAAHVHSPAGGQGLNTSVQDAYNLGWKLGAVLKGDAPAALLDS FT YEEERRPIAAQMLDLSTAVHRGEVRRGGATRQLGIGYRDSSLTVETRGAVGEEAVRAGD FT RAPDGRVDGVRLFDAFRGPHWTLLALGVDAPGGGVGAAVPVVRGGAHGAYGAGLFLVRP FT DGYVGWAGDTPDGLGAYLGRFGLGA" FT misc_feature complement(221612..222190) FT /note="Pfam match to entry PF01360 Monooxygenase, FT Monooxygenase, score 182.50, E-value 6.8e-51" FT misc_feature complement(222203..222631) FT /note="Pfam match to entry PF01494 FAD_binding_3, FAD FT binding domain, score 100.30, E-value 3.7e-26" FT RBS complement(222690..222695) FT CDS 222755..223405 FT /transl_table=11 FT /gene="SCO4871" FT /gene_synonym="SCK20.12" FT /product="putative tetR-family transcriptional regulator" FT /note="SCK20.12, probable tetR-family transcriptional FT regulator, len: 216 aa; similar to SW:TER1_ECOLI FT (EMBL:X61367) Escherichia coli tetracycline repressor FT protein class A TetR, 216 aa; fasta scores: opt: 437 FT z-score: 544.2 E(): 8.9e-23; 43.2% identity in 199 aa FT overlap. Contains Pfam match to entry PF00440 tetR, FT Bacterial regulatory proteins, tetR family and possible FT helix-turn-helix motif at residues 30..51 (+5.12 SD)" FT /db_xref="GOA:Q9EWD6" FT /db_xref="HSSP:2TCT" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9EWD6" FT /protein_id="CAC17659.1" FT /translation="MSTERRAPLDRRRVADTALKLLNEVGLDGLTLRAIARELDVKAPA FT LYWHFKDKQALLDEMATEMYRRMIAGTPLDPADTWRERLLTANRGLRAALLAYRDGAKV FT FSGSRFTGAVHAEYMEGTLRLFTAAGLTLAQAVRATTTTYLFTLGFVTEEQGVEPLPGE FT RREGFDVEERARLLADYPLTAAAGAEIFTDYDRHFEESLALVIEGVAATYGLD" FT misc_feature 222794..222934 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 63.60, E-value FT 4.3e-15" FT CDS complement(223390..224406) FT /transl_table=11 FT /gene="SCO4872" FT /gene_synonym="SCK20.13c" FT /product="hypothetical protein SCK20.13c" FT /note="SCK20.13c, unknown, len: 338 aa" FT /db_xref="UniProtKB/TrEMBL:Q9EWD5" FT /protein_id="CAC17660.1" FT /translation="MATAQETHEYPGELNDVPGWFWPLDQVLFSWFLERQERLDTRGDL FT LELGAYLGKSAILLGHRLRDGEKLTVCDLFGAQPPDAANRAEAAKSYSSLTRQAFERNY FT LSFHDTLPTIIQAPSSAVVGEVAPGSCRFVHVDASHLYEHVEGDIGAAKELLGPDGIVV FT LDDFRSEHTPGVAVAAWEAVLNRGLRPVCLSSQKLYGTWGDPEPVREELIAAFRGRDDI FT AVTVEQAAGHRLVRTRAKVKRLRPPSLPSSRHPAPVPSPEAGRTDAAPVPEQAPQPRPA FT RPAARTARPSARRDRTRKLALDLLPPLVTRAVRRYLAAQRAKAGGAGRAAGAAQSRP" FT CDS complement(224518..225456) FT /transl_table=11 FT /gene="SCO4873" FT /gene_synonym="SCK20.14c" FT /product="hypothetical protein SCK20.14c" FT /note="SCK20.14c, unknown, len: 312 aa" FT /db_xref="UniProtKB/TrEMBL:Q9EWD4" FT /protein_id="CAC17661.1" FT /translation="MNSRSLLHSSVSRRLLRPVADLIDQRIERQVRSAVRRSAAPATAD FT TARLVRDVEALRHRQLTVELLLGPGGRGISRMVGEASLEHLYAEVAALSGDRDAAERNV FT AAAFRLLVALESLGVGRIAGGTMNICGKLGTIPLLDPPNDEILEIGTLYGMFSAGLVRM FT MERDGRNPNLTIVDPFAGVQLQPGTDQRPDPTGAPVDEHAVRTNLALAGPAGAAARIRQ FT GFSEDPETRAAVSDRDYGVIVVDGDHSAEGVAKDLEWAEEIAAPGAIVVLDDYDDPSWP FT GIKDALDDRLKGSTRFTFLGKAARSAYLRAT" FT RBS complement(225467..225470) FT misc_feature 225543..225750 FT /note="Low G+C content (55.76%)" FT misc_feature 225683..225688 FT /note="AseI restriction site (ATTAAT)" FT /note="Cleavage site for AseI restriction endonuclease FT AT*TAAT" FT misc_feature complement(225683..225688) FT /note="Cleavage site for AseI restriction endonuclease FT AT*TAAT." FT CDS 225769..228654 FT /transl_table=11 FT /gene="SCO4874" FT /gene_synonym="SCK20.15" FT /product="putative integral membrane protein" FT /note="SCK20.15, possible integral membrane protein, len: FT 961 aa. Contains match to Prosite entry PS01125 ROK family FT signature. Also contains 4x degenerate repeat: DRA(S/A)G FT and possible hydrophobic membrane spanning regions" FT /db_xref="InterPro:IPR000600" FT /db_xref="UniProtKB/TrEMBL:Q9EWD3" FT /protein_id="CAC17662.1" FT /translation="MTSPHEALYATNMAWGPPRMNRSTLRGRPRQAAALLAAALTVASF FT CAADAVARSYPFGPRTRAVNDLGNQYVPFHAHLWDLLHGRSDGGLLVNWQSGFGSSFLP FT DLGTYLSSPFALLVGVFPRDEIDLAVYVVTVLKTACAGAAMAWLLLRLRPGRWWAAGLL FT GAAYALCGWSIADASYNPMWLDGLVALPLLCLVGEWALGGRRRLLGVLVVALAWIANFY FT TAYMATLGAGLFLLLRLWLCGLPRRRALAAAGRAAVTVALGVGLAAPLVTVVYFGTKHA FT YPGRVTHFAPVATEDVLARLLPTTYGFGSPALFVGTTALLLALALPFHRAAPVRVRAGW FT SGLAVAVALSMQWTPTHLAWHAFATPNGSPYRQTFVLCALLVIAAWHTLSYGVPAPRAL FT GAAGGLLALTAAVASRSGLVHSYAWPVLLLAVAGALGGLLLLRRADAGTADAASGAGPG FT AASGAGSGATSGAGSGATSGAASGAGSGAASGAGGAAARRRTALAGLAVALLVGAQLGE FT TAATSAVATRLRLNHLDDYASWGDRQRSQTQAVSGADGWPAHRTDPGREQTVGNDPMVV FT GGQGAQYYSSLTADVLSRTLTALGDGWTSRGRNVQSLDNAVTDAIFSVGARVHSPPDQH FT QRWNPRDRTPVTVSRQDVPPLVTVRPPTAPGARTGVDAFGPSPYRNQELLLGSRVYTVP FT ALTVRTGEGEQPDRASGDRASGDRAAGDRAAGDRTGTVIKAPRTKAAAARRPTIAAQCP FT AGSEVYLWAPHFSGTARLTDTPARPLTGRFTSDAAKIAAMQRLGTAPPSGRVRVELSPT FT RTGTVPDGAVGCLDTARLRTAVQQLKATGADQVTVSDGTVRAQLPAGSTGTAVLAAPRI FT AGWRCAAGGAAAESAGTYYGLIAVPLDGSATSVTCTFHPPGLRLGAAVGGASLLTLVLL FT GTLTAVRRRRSAHDPALRPATRPRERLTSAL" FT misc_feature 226546..226623 FT /note="PS01125 ROK family signature" FT misc_feature 227098..227256 FT /note="region high in alanine and glycine amino acid FT residues. High G+C (80.50%) also" FT misc_feature 227887..227946 FT /note="4x degenerate repeat translated into SCK20.15" FT RBS 228664..228667 FT CDS 228674..229624 FT /transl_table=11 FT /gene="SCO4875" FT /gene_synonym="2SCK8.01" FT /gene_synonym="SCK20.16" FT /product="putative sugar transferase" FT /note="2SCK8.01, probable sugar transferase (fragment), FT len: >256 aa; similar to SW:GTRB_BPSFX (EMBL:AF056939) FT Bacteriophage SfX (Shigella flexneri bacteriophage X) FT bactoprenol glucosyl transferase (EC 2.4.1.*) GtrB, 305 aa; FT fasta scores: opt: 659 z-score: 787.3 E(): 0; 42.3% FT identity in 246 aa overlap and to middle part of TR:O86666 FT (EMBL:AL031182) Streptomyces coelicolor putative sugar FT transferase SC4A2.10c, 478 aa; fasta scores: opt: 1022 FT z-score: 1213.9 E(): 0; 61.5% identity in 247 aa overlap. FT Contains possible hydrophobic membrane spanning regions at FT C-terminal domain" FT /note="SCK20.16, probable transferase (fragment), len: >92 FT aa; similar to N-terminal region of SW:GTRB_BPSF5 FT (EMBL:U82619) Shigella flexneri bacteriophage V bactoprenol FT glucosyl transferase (EC 2.4.1.-) GtrB, 307 aa; fasta FT scores: opt: 264 z-score: 364.3 E(): 9.3e-13; 47.3% FT identity in 91 aa overlap and to N-terminal region of FT TR:O86666 (EMBL:AL031182) Streptomyces coelicolor putative FT sugar transferase SC4A2.10c, 478 aa; fasta scores: opt: 341 FT z-score: 431.2 E(): 2.4e-18; 61.1% identity in 90 aa FT overlap" FT /db_xref="GOA:Q8CJS5" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q8CJS5" FT /protein_id="CAD55219.1" FT /translation="MLISIVAPCYNEEDVIERFHAAVQKVADDLLPLGHDMEFVYVDDG FT SRDRTLTLLEQLAEHDPRVRYVSFSRNFGKEAALLAGLRHSSGDSVVVMDADLQHPPEL FT IGRMVELRDEGYDQVLARRSRRGDRFTRTLTARLYYRLVNRLVDVELVDGVGDFRLLSR FT RVVDAVLGLTEYNRFSKGLFAWVGFPSTTFEYENAVREHGSSSWSLKSLLNYGLDGLLS FT FNNRPLRAALHLGMVLLTCAGLYTAWIVGAALVNGVETPGYVTIITVVTALAGVQMVML FT GVVGEYTGRIYYEVKGRPHFLVKATNVERTKDLIR" FT CDS 229624..230070 FT /transl_table=11 FT /gene="SCO4876" FT /gene_synonym="2SCK8.02" FT /product="putative sugar translocase" FT /note="2SCK8.02, possible sugar translocase, len: 148 aa; FT similar to SW:GTRA_BPP22 (EMBL:AF217253) Bacteriophage P22 FT bactoprenol-linked glucose translocase GtrA, 120 aa; fasta FT scores: opt: 121 z-score: 160.1 E(): 0.24; 24.2% identity FT in 124 aa overlap and to C-terminal part of TR:O86666 FT (EMBL:AL031182) Streptomyces coelicolor putative sugar FT transferase SC4A2.10c, 478 aa; fasta scores: opt: 349 FT z-score: 420.7 E(): 7.2e-16; 42.4% identity in 125 aa FT overlap. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="GOA:Q9AK50" FT /db_xref="InterPro:IPR007267" FT /db_xref="UniProtKB/TrEMBL:Q9AK50" FT /protein_id="CAC33041.1" FT /translation="MPTAQTRPMARQIATFAVVGVVNTGLYYGLYLLLLTRLPYLLAHV FT LAFLLSMVGSFFLNARFTYRTRPTWRKFLLFPLTNAANFAITTAGVYVIVDVLRAGSRF FT APLLASAAAIPVTFVVSRWIMLPHAGRAPGPETARASAEADALR" FT CDS complement(230095..231429) FT /transl_table=11 FT /gene="SCO4877" FT /gene_synonym="2SCK8.03c" FT /product="hypothetical protein 2SCK8.03c" FT /note="2SCK8.03c, unknown, len: 444 aa" FT /db_xref="InterPro:IPR010916" FT /db_xref="UniProtKB/TrEMBL:Q9AK49" FT /protein_id="CAC33042.1" FT /translation="MSTQIFLASTLYGTATLAAALDEGCFAPADRRILLVCNNATTPET FT TPALDEMPGFERLRSRFDDVVSWNEAIFPFHPGGWSPRVEDAPLWERHLRLLWDLGEDD FT VALAVESIQVHPALGVAQIFTDAPLTVYADGLMSYGPTRNKLDPLVGTRVERLLHLDLV FT PGLAPLLLTEFDVPARIVPTPAFTKVLAELADTDAALPGGEGSALLLGQYLSALGILTA FT EEEEDLHVRMLTGAVGLGHSRVVFKPHPTAPARFTRTLEQEAEKLGVELTVLDTPVLAE FT VLYRRMRPALVVGCFSTALLTASALYGLPVARVGTETLLDRLTPYENSNRVPVTIVDAL FT LPEPADRDAVTEGRRGLDTEALAALVRAVGYAMQPKILPELRPAAEEFLRTGLDARTRR FT YFKKRRLTSLGLPGGVPERLAFLPRNAAARRVVRRARAIRRSIKR" FT CDS complement(231426..232406) FT /transl_table=11 FT /gene="SCO4878" FT /gene_synonym="2SCK8.04c" FT /product="putative glycosyltransferase" FT /note="2SCK8.04c, possible glycosyltransferase, len: 326 FT aa; similar to TR:AAG44714 (EMBL:AF267127) Lactobacillus FT delbrueckii glycosyltransferase EpsJ, 327 aa; fasta scores: FT opt: 319 z-score: 393.4 E(): 2.5e-14; 30.5% identity in 236 FT aa overlap. Contains Pfam match to entry PF00535 FT Glycos_transf_2, Glycosyl transferases" FT /db_xref="GOA:Q9AK48" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q9AK48" FT /protein_id="CAC33043.1" FT /translation="MPKLSVIVPFYNVRQYAPDTLRSLRANARDDFEFILVDDCSSDGT FT ADLLARAESELPGAVLVRHERNGGLATARNTGIDRARGEYLTFLDGDDWLAPGYYERLL FT AAIEELGCDFVRTDHVQCTARARVVHRVPHGRRNVSLRPRDAILPAHRSTSVDYAYAWA FT GVYHRRLVDRGLLHFTDGLRTAEDRPWIWRLHREAESFAVTGLLGVFYRRGVASSLTQI FT GDVRQLDFIRAFDEVVAGAAEDADAARLLPKAVRTYCAIISHHLGSVERFEPAVARKLK FT AMSAAALRRMPQGALDEVLGSMDTERATLLRRLRRRGPQGAEVAA" FT RBS complement(231435..231441) FT misc_feature complement(231882..232394) FT /note="Pfam match to entry PF00535 Glycos_transf_2, FT Glycosyl transferases, score 144.80, E-value 1.5e-39" FT CDS 232605..233936 FT /transl_table=11 FT /gene="SCO4879" FT /gene_synonym="2SCK8.05" FT /product="conserved hypothetical protein" FT /note="2SCK8.05, hypothetical protein, len: 443 aa; central FT region presents low similarity with TR:Q9K1M6 FT (EMBL:AE002366) Neisseria meningitidis hypothetical protein FT NMB0065, 308 aa; fasta scores: opt: 341 z-score: 354.4 E(): FT 3.6e-12; 26.6% identity in 334 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9AK47" FT /protein_id="CAC33044.1" FT /translation="MPASATKALRVAVLADSDTRWKWGALTATRVCPGDTEIHLDGYLL FT RGRATPTARQLREVGVDADSLREVTAVEFLRAMEGAGEGDGEPYDVLVLALVGGGVQAM FT LHGLGRVWRDRAERPVVVTGYVGVVYEKLADGLLLRHGADLVLANSRQDAERFRAVYEG FT VGADTAAVTEVALPFLGGAAHGGEHDPYTVVFAAQPSVPDSRKDRTYLLERLIRHARLH FT PEREVLLKLRSRPGEHTTHIEELPYQKLVQRADPPPNFRLVYGHMGEVLDRTDLLVTVS FT STAALESLHRRIPTVVLTDLGVREALGNHHFVGSGCLASWDQLDAGHRPAPDAEWVARQ FT GVAADGGYETAFDEARKRIAALLSRPAGLPPLAPYYTPVTAPGYLPGILARHHLAPDGT FT PLPGAPAADRAPGPVRQVVRRAARGAYRHGVQRVAPVIRRMGEL" FT RBS 234111..234116 FT CDS 234125..235399 FT /transl_table=11 FT /gene="SCO4880" FT /gene_synonym="2SCK8.06" FT /product="putative transferase" FT /note="2SCK8.06, possible transferase, len: 424 aa; similar FT to TR:O88719 (EMBL:AJ006215) Mus musculus FT CMP-N-acetylneuraminic acid synthetase (EC 2.7.7.43) CmaS, FT 432 aa; fasta scores: opt: 361 z-score: 400.1 E(): 1e-14; FT 30.3% identity in 389 aa overlap. Contains Pfam matches to FT entries PF02348 Cytidylyl_trans, Cytidylyl transferase and FT PF00702 Hydrolase, haloacid dehalogenase-like hydrolase" FT /db_xref="GOA:Q9AK46" FT /db_xref="HSSP:1EZI" FT /db_xref="InterPro:IPR005834" FT /db_xref="UniProtKB/TrEMBL:Q9AK46" FT /protein_id="CAC33045.1" FT /translation="MSNSQAGPGASVRRVLAVIPARGGSKGVPAKNLAPVGGVPLVVRA FT VRECLAARLVTDVVVSTDDQAIAAAAREAGAEVVLRPAAIAGDTATSEAAVLHAMDAHE FT ALHGAAVDVVLLVQCTSPFLVREDVDGVAGAVVEDGADTAVTVAPFHGFVWRDGADEPG FT GADGGHGVNHDKAYRPRRQDRPQDLLETGAAYAMAAPGFRKHRHRFFGRTDLVRTDPAR FT VLEIDDPHDLARARALAPHFDTARPGALPTAADIDAVVLDFDGTQTDDRVLIDTDGREF FT VSVHRGDGLGIAALRRSGLTMLILSTEVNPVVAARARKLKLPVLHGIDRKDLALKQWCE FT EQGIAPERVLYVGNDVNDLPCFALVGWPVAVASAHDAVRGAARAVTTVPGGEGAVREIA FT AWLLGPSLDALGPASETTPTLTQSK" FT misc_feature 234170..234892 FT /note="Pfam match to entry PF02348 Cytidylyl_trans, FT Cytidylyl transferase, score 69.20, E-value 8.5e-17" FT misc_feature 234521..235249 FT /note="Pfam match to entry PF00702 Hydrolase, haloacid FT dehalogenase-like hydrolase, score 11.40, E-value 0.024" FT CDS 235413..236351 FT /transl_table=11 FT /gene="SCO4881" FT /gene_synonym="2SCK8.07" FT /product="putative polysaccharide biosynthesis related FT protein" FT /note="2SCK8.07, possible polysaccharide biosynthesis FT related protein, len: 312 aa; similar to SW:SPSE_BACSU FT (EMBL:X73124) Bacillus subtilis spore coat polysaccharide FT biosynthesis protein SpsE, 373 aa; fasta scores: opt: 473 FT z-score: 554.3 E(): 2.6e-23; 32.2% identity in 295 aa FT overlap and to TR:Q9NR45 (EMBL:AF257466) Homo sapiens FT N-acetylneuraminic acid phosphate synthase, 359 aa; fasta FT scores: opt: 660 z-score: 771.2 E(): 0; 38.4% identity in FT 294 aa overlap. Contains matches to Prosite entries PS00017 FT ATP/GTP-binding site motif A (P-loop) and PS00639 FT Eukaryotic thiol (cysteine) proteases histidine active FT site" FT /db_xref="GOA:Q9AK45" FT /db_xref="InterPro:IPR013132" FT /db_xref="UniProtKB/TrEMBL:Q9AK45" FT /protein_id="CAC33046.1" FT /translation="MSTNSRIRTFGTREAGPGRPVYITGEIGINHNGELENAFKLIDAA FT AEAGCDAVKFQKRTPEICTPRDQWDIERDTPWGRMTYIDYRHRVEFGEDEYRQIDDYCR FT TKNIDWFASPWDTEAVAFLEKFDVPAHKVASASLTDDELLRALRATGKTVILSTGMSTP FT KQIRHAVEVLGSDNILMCHATSTYPAQAEELNLRVINTLQQEYPNVPIGYSGHETGLQT FT TLAAVALGATFVERHITLDRAMWGSDQAASVEPQGLTRLVRDIRTIEASLGDGVKKVYD FT SELGPMKKLRRVTGVVAEAEIAAAAGEPVTV" FT misc_feature 235848..235871 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 235908..235940 FT /note="PS00639 Eukaryotic thiol (cysteine) proteases FT histidine active site" FT CDS 236395..237462 FT /transl_table=11 FT /gene="SCO4882" FT /gene_synonym="2SCK8.08" FT /product="hypothetical protein 2SCK8.08" FT /note="2SCK8.08, unknown, len: 355 aa" FT /db_xref="UniProtKB/TrEMBL:Q9AK44" FT /protein_id="CAC33047.1" FT /translation="MSPRAGNAGPRTLAFVESPVQLLNVLEWAHTRAPGAELTLVVLSP FT VDPMTRGQLRRMAELARKEGHEIRWEEARGGATAPFRTVGGLTTPLRQADRIVMGDPFS FT RYVQLLLTITRAHDLVVVDDGTATMEFVTQLAHGERLVRWHRKGSRPGPRDLLFAPVSR FT SARHRLTPAPDRQVSVFSSMPIEDVPEGATVTANDFAWTRSRFGPPRITKGADMVGTSL FT VETGVVDADRYVDAVHALAKTHGAARYFAHRRESAVKLHRLAVETGLQIVRPDLPLELI FT ARRGPIGRTILSFPSTVVHTLPLALAGTDVRVAVCDIDPAWLTESASPRASGFLSGVTG FT SARDVHRLSAVAGTA" FT CDS 237702..238934 FT /transl_table=11 FT /gene="SCO4883" FT /gene_synonym="2SCK8.09" FT /product="putative peptidase" FT /note="2SCK8.09, probable peptidase, len: 410 aa; similar FT to SW:CBPX_SULSO (EMBL:Z48497) Sulfolobus solfataricus FT thermostable carboxypeptidase (EC 3.4.17.*) CpsA, 393 aa; FT fasta scores: opt: 687 z-score: 803.2 E(): 0; 32.0% FT identity in 372 aa overlap. Contains Pfam match to entry FT PF01546 Peptidase_M20, Peptidase family M20/M25/M40" FT /db_xref="GOA:Q9AK43" FT /db_xref="InterPro:IPR010168" FT /db_xref="UniProtKB/TrEMBL:Q9AK43" FT /protein_id="CAC33048.1" FT /translation="MSPESEADTPGEAALPGTLPDALRAELVAFRRDLHMHPELGNQEF FT RTTAAIKERLERAGLKPRVLPIGTGLVCDIGTDSGQWSGGPRMLALRADIDALPIPDTK FT SECAYRSQVPDRAHACGHDVHTTVVLGTGLVLAALHEQGLLPRPVRLVFQPAEEVLPGG FT AADAIEGGALDGVRRILAVHCDPRVDAGRIGLRVGPITSACDRLEIALNGPGGHTARPH FT LTTDLVTAAARVVTDVPPLVARRVDSRSGLALTWGRIESGHAPNVIPQHAELAGTVRCL FT DLDAWRQAPDLVMGAIDEIADLYRAKSEITYVRGVPPVVNEVTSTELLQAAMVARRGTD FT AVESTEQSLGGEDFSWYLEHVPGAMARLGVRPPGERTVRDLHQGDFDVDEHAITVGVEM FT FTAAALIDAVQ" FT misc_feature 237771..238754 FT /note="Pfam match to entry PF01546 Peptidase_M20, Peptidase FT family M20/M25/M40, score 100.40, E-value 7.2e-28" FT CDS 239154..240197 FT /transl_table=11 FT /gene="SCO4884" FT /gene_synonym="2SCK8.10" FT /product="putative lipoprotein" FT /note="2SCK8.10, probable lipoprotein, len: 347 aa; similar FT to SW:YUFN_BACSU (EMBL:Z93937) Bacillus subtilis FT hypothetical lipoprotein precursor YufN, 350 aa; fasta FT scores: opt: 690 z-score: 727.5 E(): 0; 37.4% identity in FT 348 aa overlap, to TR:CAC14304 (EMBL:AJ276209) Clostridium FT sticklandii putative substrate binding lipoprotein FT precursor of an ABC transporter BmpA, 349 aa; fasta scores: FT opt: 557 z-score: 589.0 E(): 3.1e-25; 36.6% identity in 352 FT aa overlap and to Streptomyces coelicolor probable FT lipoprotein 2SCK8.11, 348 aa; fasta scores: opt: 1727 FT z-score: 1625.1 E(): 0; 78.4% identity in 347 aa overlap. FT Contains Pfam match to entry PF02608 Bmp and properly FT positioned match to Prosite entry PS00013 Prokaryotic FT membrane lipoprotein lipid attachment site. Also contains FT possible N-terminal region signal peptide sequence" FT /db_xref="GOA:Q9AK42" FT /db_xref="InterPro:IPR003760" FT /db_xref="UniProtKB/TrEMBL:Q9AK42" FT /protein_id="CAC33049.1" FT /translation="MRRTSRLIRVAVGVASLALAATACGGTSGESGDDGGDDKGLAIAY FT DVGGKGDQSFNDAAYAGLERAKKEFGYKTADIEPTDGETDADKEQRLTSLAKQGYNPVI FT GVGFAYGPAMKAVAAKYPDTTFGIVDSVVEGKNVASLVFAENEASYLAGVVAAKATKSK FT TVGFVGGVDVPLIHKFQAGYEQGVKDTDPKVKVVSQYLTQTAEEGGFSSPDKGKAAAEG FT QIEKKADVVYAAAGLSGQGVIEAAAKAKIWAIGVDSDQYKQEALATYKDSILTSALKDI FT NGAVFALAKSVEDGKPLTGTHTFDLKSDGVGLSDSNPKFAEVPGAEEAVEKAKAGIVDG FT SIKVATE" FT misc_feature 239190..240191 FT /note="Pfam match to entry PF02608 Bmp, , score 207.30, FT E-value 2.4e-58" FT misc_feature 239193..239225 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS 240457..240462 FT CDS 240471..241517 FT /transl_table=11 FT /gene="SCO4885" FT /gene_synonym="2SCK8.11" FT /product="putative lipoprotein" FT /note="2SCK8.11, probable lipoprotein, len: 348 aa; similar FT to SW:YUFN_BACSU (EMBL:Z93937) Bacillus subtilis FT hypothetical lipoprotein precursor YufN, 350 aa; fasta FT scores: opt: 663 z-score: 689.2 E(): 8e-31; 36.8% identity FT in 334 aa overlap, to TR:CAC14304 (EMBL:AJ276209) FT Clostridium sticklandii putative substrate binding FT lipoprotein precursor of an ABC transporter BmpA, 349 aa; FT fasta scores: opt: 560 z-score: 583.6 E(): 6e-25; 36.1% FT identity in 355 aa overlap and to Streptomyces coelicolor FT probable lipoprotein 2SCK8.10, 347 aa; fasta scores: opt: FT 1727 z-score: 1622.6 E(): 0; 78.4% identity in 347 aa FT overlap. Contains Pfam match to entry PF02608 Bmp and FT properly positioned match to Prosite entry PS00013 FT Prokaryotic membrane lipoprotein lipid attachment site. FT Also contains possible N-terminal region signal peptide FT sequence" FT /db_xref="GOA:Q9AK41" FT /db_xref="InterPro:IPR003760" FT /db_xref="UniProtKB/TrEMBL:Q9AK41" FT /protein_id="CAC33050.1" FT /translation="MRRISRITVAGAATASLALALAACGGTSTDSGSESKGDKGLAIAY FT DVGGKGDQSFNDAAYAGLEQAKKEFGYETADVEPTDGETDADKEQRLSSLAKQGYNPVV FT GIGYAYASAMKNVAAKYPDTTFGIVDDATIEAKNVADLVFNEQEASYLAGVAAAKSTKT FT NTVGFVGGVDVPLIHKFQAGYEQGVKDTDPKVKVVSQYLTQTAEEGGFSSPDKGKTAAE FT GQIEKKADVVYAAAGLSGQGVIEAAAANKVWAIGVDSDQYKQEALAKYKDSILTSATKD FT VAKAVYSLAKSVEDGKPETGIVRGDLKSGEVGLSDSNPKFADDAELQAAIKSAKEKIIS FT GEIKVKSS" FT misc_feature 240507..241511 FT /note="Pfam match to entry PF02608 Bmp, , score 228.20, FT E-value 1.2e-64" FT misc_feature 240510..240542 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT stem_loop 241560..241645 FT /note="possible stem loop. Score 52: 31/42 (73%) matches, 0 FT gaps" FT CDS 241754..243367 FT /transl_table= |