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EBI DbfetchID AL939116; SV 1; linear; genomic DNA; STD; PRO; 293050 BP. XX AC AL939116; AL035636; AL049573; AL049628; AL049630; AL049645; AL049661; AC AL049707; AL049763; AL049819; AL049841; AL079345; AL133236; AL133252; XX DT 25-OCT-2002 (Rel. 73, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 4) XX DE Streptomyces coelicolor A3(2) complete genome; segment 13/29 XX KW . XX OS Streptomyces coelicolor OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Streptomycineae; Streptomycetaceae; Streptomyces. XX RN [1] RP 1-293050 RA Bentley S.D.; RT ; RL Submitted (09-MAY-2002) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Streptomyces sequencing team, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL sdb@sanger.ac.uk XX RN [2] RX DOI; 10.1038/417141a RX PUBMED; 12000953. RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L., RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H., RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E., RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D., RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.; RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor RT A3(2)"; RL Nature 417(6885):141-147(2002). XX DR EMBL-CON; AL645882. DR RFAM; RF01118; PK-G12rRNA. DR SILVA-LSU; AL939116. DR SILVA-SSU; AL939116. XX FH Key Location/Qualifiers FH FT source 1..293050 FT /organism="Streptomyces coelicolor" FT /strain="A3(2)" FT /mol_type="genomic DNA" FT /db_xref="taxon:1902" FT CDS 57..713 FT /transl_table=11 FT /gene="SCO3282" FT /gene_synonym="SCE39.32" FT /product="putative precorrin-8X methylmutase" FT /note="SCE39.32, possible precorrin-8X methylmutase, len: FT 218 aa; similar to many e.g. SW:COBH_PSEDE Precorrin-8X FT methylmutase from Pseudomonas denitrificans (210 aa) fasta FT scores; opt: 868, z-score: 1000.1, E(): 0, (64.2% identity FT in 204 aa overlap) and SW:COBH_MYCTU precorrin-8X FT methylmutase from Mycobacterium tuberculosis (208 aa) fasta FT scores; opt: 852, z-score: 982.0, E(): 0, (64.1% identity FT in 206 aa overlap)." FT /db_xref="GOA:Q9X8F5" FT /db_xref="HSSP:1F2V" FT /db_xref="InterPro:IPR003722" FT /db_xref="UniProtKB/TrEMBL:Q9X8F5" FT /protein_id="CAB40340.1" FT /translation="MTPYDSKNEYEYEYEKDGAAIYRQSFATIRAEADLSGLPADVGRV FT AVRMIHACGMVDLVRDLSWSPGVVSRAREALRAGAPVLCDVRMVASGVTRARLPADNDV FT VCTLSDPAVPELAARLGTTRSAAALELWRDRLDGAVVAVGNAPTALFRLLEMIGEGAPR FT PAAVIGVPVGFVGAAESKEALAAHPSGVEHLVVRGRRGGSALAAAAVNAIASEEE" FT CDS complement(745..1512) FT /transl_table=11 FT /gene="SCO3283" FT /gene_synonym="SCE39.33c" FT /product="putative precorrin-6X reductase" FT /note="SCE39.33c, possible precorrin-6X reductase, len: 255 FT aa; similar to many e.g. SW:COBK_RHOSO precorrin-6X FT reductase from Rhodococcus sp. (248 aa) fasta scores; opt: FT 873, z-score: 978.5, E(): 0, (55.1% identity in 247 aa FT overlap) and SW:COBK_MYCTU precorrin-6X reductase from FT Mycobacterium tuberculosis (244 aa) fasta scores; opt: 690, FT z-score: 775.5, E(): 0, (50.4% identity in 244 aa overlap)" FT /db_xref="GOA:Q9X8F6" FT /db_xref="InterPro:IPR003723" FT /db_xref="UniProtKB/TrEMBL:Q9X8F6" FT /protein_id="CAB40341.1" FT /translation="MHVLILGGTTEARRLAELLAAGQPAGPRVTTSLAGRVSAPRTPPG FT EVRVGGFGGAEGLAAWLREHAVGLLVDATHPFAGTITRNAAHAAATAGVPLLVLRRPGW FT RPVEGDVWHEAGSLAEAAALLPALGRRVFLTTGRTGLAVFAPLADPWFLVRSVDAPEGP FT RPPRTEVLLDRGPFTLDGERELLRRHRIDVLVTKDSGGAATAPKLTAAREAGLPVVVVR FT RPPVPEGVRVVAEPGQAARWVAEARARRSPRRP" FT CDS 1683..3818 FT /transl_table=11 FT /gene="SCO3284" FT /gene_synonym="SCE15.01" FT /gene_synonym="SCE39.34" FT /product="conserved hypothetical protein" FT /note="SCE15.01, partial CDS, conserved hypothetical FT protein, len: >436aa; similar to C-terminal region of FT TR:CAA22732 (EMBL:AL035161) another conserved hypothetical FT protein from Streptomyces coelicolor (860 aa) fasta scores; FT opt: 922, z-score: 1011.5, E(): 0, (39.5% identity in 425 FT aa overlap)." FT /note="SCE39.34, unknown, len: >307aa; similar to FT TR:E1370406 (EMBL:AL035161) conserved hypothetical protein FT from Streptomyces coelicolor (860 aa) fasta scores; opt: FT 254, z-score: 277.0, E(): 4e-08, (29.2% identity in 277 aa FT overlap) TR:O86875 (EMBL:U22894) hypothetical protein from FT Streptomyces lividans (547 aa) fasta scores; opt: 226, FT z-score: 249.7, E(): 1.3e-06, (33.0% identity in 197 aa FT overlap)." FT /db_xref="GOA:Q8CJX1" FT /db_xref="InterPro:IPR010822" FT /db_xref="UniProtKB/TrEMBL:Q8CJX1" FT /protein_id="CAD55311.1" FT /translation="MRKARGKAAKGGRAVTGDPIGDAAVLSALFANSPQGLFVFDSEQK FT VTRYNPAGRGVRGLPEEDVVGQGIADFVPGFEAVELQGLIDEVLATGEALRGRLVRGRA FT PSGPHRTLAVEVSLFPLRDLGDGKPGLVGVVEDVTERQAAADRLAVLSEVHATVGSTLD FT VRTTGDELVAALVPAFADAATVDLLDDGVVAAERAAGPPPTEVPLRRVAFAPPAAEVSR FT KEGDSRPLPFPTPYTQVLNDMRARLVRVSSDDPWLSADPEALEPLVRTGVHSMIVAPLL FT ARDTVLGLLTLYRHRTDPFEEADLDVARQAAFTASVHLDNAHSYRREHTVAAALQRRLQ FT PGAIPLLSAVETAHVYLPESAGGDWFDVVPLSGTRVALVVGDVTGHGIEAAATMGQLRL FT AVRTLALRDLETDELLTHLDEVASQLADASGPGGNTPVATCAVTVYNPVSRHCTMVRAG FT HPAPVVIDPDGVPRAVDVPQGPPLGTGGGHVFTPAVLELAPGTLLALHTNGLTRGNGDE FT GEAARRRLEHILASTTRPLQELCDTAVYHMAPSRHDDAVLLLARTRALPPEHVADWTLP FT ADASVVGTARRLVDRQLASWGLDEAAYTTGLVVSELVTNAIRYGKGPVRLRLIRDRGRL FT LTEVTDANSASPHLRRARENDEGGRGLFIVMRLSTHWGVRHSRHDKTIWSEQRLDAGPP FT DTSGLLDAFDVTDAAGL" FT CDS complement(3855..9173) FT /transl_table=11 FT /gene="SCO3285" FT /gene_synonym="SCE15.02c" FT /product="putative large glycine/alanine rich protein" FT /note="SCE15.02c, large glycine/alanine rich protein, len: FT 1772aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X877" FT /protein_id="CAB41271.1" FT /translation="MATAPEKAATGTHDTGDTADAGAYEVLRDRLAAQTADLARRAGLL FT NARRVEEFGSARLELASTERLRTEHPGVPCDLAAVGDALLLGSTGRPGHRTGTAAVADV FT FTLYDRDLNPLPESAVPGLLDDPAFVREFADLHRYYRQARLLRLRPVGGRLLAVFRTGE FT KAADIRVLRWELTEDGRAAFLDARGERDDVFPPSHDFEWTAATREDHVLGRHPHVSVRG FT EFHVSAVGGALTVKLEDDTETAGGVYSEPVDEPLQSLADADIAHARVGALILLRVRPYK FT EDTDRHLVFNTLTKSVVRLDGIGAACRRLPDDQGIVFPGGYCLATGVHKTYELDAAGLE FT FEREVRSPNGEDVLYAFHARGESRGLLLSYNTIRKEVANPLPCRGWALAEDGTFTVLRA FT DGDEPAQVHPVQLWHSPYVSDTHAAAAPAGSGPLARVGNADLVRGISACLSVAGAVGDG FT ITTAEGYRALAASCVRAADGHHWLGEADLGDLAGALAAVRETAEQVLAEFETVRDLTRR FT AAEARDEAAERIASVVRRLRGEAPKEAAAWVRGLTELRHAHGHLLTVKEMRYADAPGID FT ALAGEAEASLAELGRRAVAFLAREDAFDAQRADVEALVADAEAIATVAEAGPVAARLDE FT LADGLRTVTDVVAELDVGDATVRTALLERVAAVLGGVNRARATLDARRRALLDREGRAE FT FTAETALLGQAVTAALAAADTPERCDDQLARLLARLEDLESRFAEFDGFLAELADKRTE FT IYDALAARKQALSDTRARRAEQLAASAARIMETIARRCATLADADAVSTYFASDPMPAK FT VRRTAEELRALGDSVRAEELDGRLKSARQEASRALRDRTDLYADDGRTLRLGAHRFAVN FT TQPLDLTLVPDGDGLAFALTGTDYRSPVTDPDFAATRAHWDRTLPSESPGVYRAEHLAA FT RLLRQHGASALAAADDLPALVREAAQEAYDEGYERGVHDHDATLVLTALLPLYEKAGTL FT VHEPAARAAAQLFWAHGTTPRAREAWTRRARSLARARDTFGLSAAIAALEEELAGAVGT FT WPGPGEMVAGAGPVPGGAAAGAPAEDGRAGVPPAATGGAVGSLPGASGPPSGAGAPLGA FT AGSAAGTAGSGAGAPGSGVGAAVSGAAGDAGRAAGVPRAAGGTARSAEGFAGAAGAVGS FT ATGTSGPPAGAPGSGAEHARAAAAYLFHELTTEPEGFVLGAGTRTLLEKFRRTVGTPAY FT DEDLAALDDLAARGQLAEAWISSYAAAGGTGLTPGDLAEAVAAELCPDLPRYDGDVPPT FT ATAEGLLGTHPRITGGRLQLRLDEFLARTARFAAHDVPEFRAYQRRRTALVGAERARLR FT LDDHRPRVMSAFVRNRLVDEVYLPLVGDSLAKQLGATGDGKRTDTGGLLLLLSPPGYGK FT TTLVEYVAERLGLMLVKVGGPALGHGVTSLDPADAPNATARQEVEKINFALASANNTLL FT YLDDIQHTSPELLQKFIPLCDATRRVDGVWNGAPRTYDLRGKRFAVCMAGNPYTESGAR FT FQVPDMLANRADVWNLGDVLTGKKEAFALSFLENALTANPVLAPLAGRDRADLELLVRL FT ATDDPTARADRLDHAYPPAELERILSVLRHLVAARETVLAVNAAYIASAARSDETRTEP FT AFRLQGSYRNMNKIAQRVRPVMNDAERAAVLDDHYTAEAQTLTHGAEANLLKLAELRGT FT LTPEQADRWAEVRTAHVRARTLGGPDDDPLTRAVAALGLLADRVAAVESAITRAADPRH FT LLANPHARHAAGGTER" FT CDS complement(9259..11292) FT /transl_table=11 FT /gene="SCO3286" FT /gene_synonym="SCE15.03c" FT /product="putative secreted protein" FT /note="SCE15.03, putative secreted protein, len: 677 aa; FT weak similarity to SW:YQIK_ECOLI hypothetical protein from FT Escherichia coli (553 aa) fasta scores; opt: 542, z-score: FT 501.2, E(): 1.3e-20, (27.0% identity in 504 aa overlap). FT Contains possible N-terminal region signal peptide sequence FT also contains a highly hidrophilic central part of the FT protein" FT /db_xref="InterPro:IPR001107" FT /db_xref="UniProtKB/TrEMBL:Q9X878" FT /protein_id="CAB41272.1" FT /translation="MEVIGVLALVCLLLVVLVLFGVSRLFRKVEQGKALIVSKMRKVDV FT TFTGQVVLPVLHKAEVMDISVKTIEITRAGKEGLICRDNIRADIRISFFVKVNKTAEDV FT VKVAQAVGTARASDRDTLQELFHAKFSEALKTVGKQLDFTDLYTKREELRYRIIEVIGV FT DLSGYHLEDAAIDYLEQTPLTQLDPANVLDAQGIRKITELTAVEHVRTNEARRTEEKEI FT TRQNVDAREAVLELERRQADAEIKQKREIDTTRAREEAETARVVEEERLRAQAAFLRTE FT EQLGVQRENQAREVAVAAKNRERVIAVENERIEKDRMLEAIGRERETELTRIAAEKEVE FT AERRDIAEVIRERVAVDRTVAEQEESIKKLRAVEEAERDRQTVIIAAEAQAQERLVKDI FT KAAEAAEAAATHRAAEELTMAEARLKSADLEAQAKLRMAEGIQAEAAAAGLAAVQVRDK FT EAEVIEKAGRAEAEATGARMRAEAEGARAKALAEAEAIGSRLKAEAAGLTEKAAAMAAL FT DDASRGHEEYRLRLEAEKDIRLAGLDVQRQVAEAQATVLATGLENADIDIVGGDTVFFD FT RLMSSVALGKGVDGFVKHSETAQALAGPWLDGSSSFTDDLTRVLGSFSTADVQNLTVSA FT LLMKLMKSGGTDAGQVQRLLDRAGELGLADTPLTALNGTARV" FT CDS 11379..11897 FT /transl_table=11 FT /gene="SCO3287" FT /gene_synonym="SCE15.04" FT /product="putative serine/arginine rich protein" FT /note="SCE15.04, serine/arginine rich protein, len: 172aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X879" FT /protein_id="CAB41273.1" FT /translation="MRTGVVPGASLRTDRARAGPRQRRKAGLRRRGGRVPRRRRRAGRG FT RDRRDGGGAGGGAGRTDCASSSSSSSGPLRAVLPVRPMVRDGATYPHCRFPEAFTRAWV FT PVNRPGAIGGTSSGTINGPAIPEADRKRIGTPEIWFRKRRHWSDRSMHKAHRPTRGACR FT IRPAGYRRQ" FT CDS 11906..12637 FT /transl_table=11 FT /gene="SCO3288" FT /gene_synonym="SCE15.05" FT /product="putative integral membrane protein" FT /note="SCE15.05, possible integral membrane protein, len: FT 243aa; similar to TR:Q53715 (EMBL:L06249) hypothetical FT protein from Streptomyces antibioticus (234 aa) fasta FT scores; opt: 292, z-score: 298.6, E(): 2.5e-09, (33.2% FT identity in 241 aa overlap). Contains a possible membrane FT spanning hydrophobic region and a 8x5 degenerate repeat of FT GT***." FT /db_xref="UniProtKB/TrEMBL:Q9X880" FT /protein_id="CAB41274.1" FT /translation="MSSTRVPPGARGSYPAPGLALTPGPVRNQALTVIAVPFVLIVVLA FT VVLATTGPDDGAPATDGLYGSGALPDWGSGTTDDGTTDDGTSGDGTDPDGTYGNGTYED FT GTYGDGTYDNDPYGDGTADETPTDDTTTDTATDDTATEDTTANGSGPEATVTAYFDAIN FT NRDFAAAWELGGKNLDQDYDSFVAGFGTTQRDDVTVTGTSGDDVSVTVVAWETDGTQTT FT FEGTYTVSGGVITSADMREGN" FT repeat_region 12128..12247 FT /note="Translation gives 8x5 degenerate repeat of GT***." FT CDS 12644..14254 FT /transl_table=11 FT /gene="SCO3289" FT /gene_synonym="SCE15.06" FT /product="putative large membrane protein" FT /note="SCE15.06, possible large membrane protein, len: 536 FT aa; contains a possible membrane spanning hydrophobic FT region" FT /db_xref="UniProtKB/TrEMBL:Q9X881" FT /protein_id="CAB41275.1" FT /translation="MTTHAAPPPPDTTSNATRLLCAGTYLDPHYRKAVIRELLTHRYRV FT VAPSYGYDAAPVLAHALAAHNLRRNQLIALAAGAVVIALLMAAGVLGGWTAALFAFWLA FT WATMFLRRLAILQTLAEHLAPPTDDRTGFDGSHPVTSRLTPELVGKINREQASDTVYYG FT GYKPFIGAGHSVKRWANAELLLGAPKSRAGALGQNLLNGHVPAQHGPADGTNGTNGTNG FT TDGGGRTERKPIIPFTVDDITTRVCEELLAELRDKPAPSHRVELLSVDRRRFTKAVRTA FT EGSDSVAVLLDTPDPGHPDHTAAHWREDYDARREYLCVRIGAWQQELVTSVFIGFDIKG FT STLHTEFYTYVLGPLPESFHLADRLPAAIDGRLMCRIAWDVTRSAPGELLRLITNPLRE FT RLPSRLSTDTVRKLVGEPADTSEFRLGRYALTAVDCGARTSVRELAPDHDFHHFFQESD FT AIKYIQIIERHLLQIVGDFLRDHDVDTREHEANQTNILQQNFGANSTNNFGGNQSVGNT FT NTTQTFGNNSGVTREARQA" FT CDS 14251..15000 FT /transl_table=11 FT /gene="SCO3290" FT /gene_synonym="SCE15.07" FT /product="hypothetical protein" FT /note="SCE15.07, unknown, len: 249aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X882" FT /protein_id="CAB41276.1" FT /translation="MSGQQFHGNSFGQGSTNNFGGNQSAGNTDTTQTFGDNSPVHAAPP FT APSAPPAQPYADGWRRPAAPVPGDAERARSVFVVHGRDDQVRREMYELLRRLDLRPKEW FT EDLVRATGQASPFLGDVVAGAPAQAQAALVLLTPDDVVTLHPELRGHNEPDHETRPVCQ FT PRPNVLIELGMVLMAYPERTLIVEVGGVRPIADIAGRNVIRFDGSDTALGKVVERLKLA FT GCTVNDTGSDWRQTYPFRHLSAYHRRP" FT stem_loop 15064..15113 FT /note="Imperfect inverted repeat (20/22) with 6 base loop." FT CDS 15228..16661 FT /transl_table=11 FT /gene="SCO3291" FT /gene_synonym="SCE15.08" FT /product="putative regulatory protein" FT /note="SCE15.08, possible regulatory protein, len: 477 aa; FT N-terminal region similar to others from Actinomycetes eg. FT SW:DNRI_STRPE regulatory protein from Streptomyces FT peucetius (272 aa) fasta scores; opt: 143, z-score: 162.9, FT E(): 0.092, (27.8% identity in 241 aa overlap)." FT /db_xref="GOA:Q9X883" FT /db_xref="InterPro:IPR005158" FT /db_xref="UniProtKB/TrEMBL:Q9X883" FT /protein_id="CAB41277.1" FT /translation="MARIRVSVLGPARLEVDGVPARLTPLTTRLLVRLVAADGEPVPVR FT RLHRDVWALDGEQPHAAQRHRNEVQKRVLELRRALDPAQRGDGARVLRTEQLLAGPAPE FT TAYRLVLAPGELDCAEFTDLVDSALLAAPASAADRLAAALALVRGRPLAEAGDEDFARP FT LARRLTALYETARRQLIRSRMDLGRHDLALPVAERMARERPDDQDVAELLGALRARLRE FT RHGRELLRQPFPGAGDLVVVRGDLFDQDDANLVVGFTDTFDTATEQDLVISRDSVQGQL FT VERLFGGERKLLDDRIQAGLRAFRPVRTERPQDKPRGRRVRYPLGTTVPLTVDGRRVFA FT VAYSRLGNDLVARSGPADLRASLDTLWPAVARYGMYRPLAIPLIGSGLARIVELDRTRL FT LLMIVESFADHCRRDPATAPELRVVIRPADLERTDLSVLGTYLRTTRLPGAGADVGAGT FT GSQDTGAGAGDSGGAYGRR" FT repeat_region 16569..16604 FT /note="Perfect inverted repeat (18/18)." FT CDS complement(16789..17298) FT /transl_table=11 FT /gene="SCO3292" FT /gene_synonym="SCE15.09c" FT /product="hypothetical protein" FT /note="SCE15.09c, unknown, len: 169aa;" FT /db_xref="InterPro:IPR019775" FT /db_xref="UniProtKB/TrEMBL:Q9X884" FT /protein_id="CAB41278.1" FT /translation="MTALAVTGHMDLTEESVPAVRAALDGLLARYRDSGPGKTLVGISC FT IARGADSLFAEAVLAVGGRLVVVVPSRDYRRSTVEPDDAPLFDRLAAAADEVVVLPRER FT ADRQAYEAANALLLARADRLVAVWNGEPPSGRGGGTADLVLAAREAGIPVDVVWPAGAA FT RRADSR" FT CDS complement(17358..17861) FT /transl_table=11 FT /gene="SCO3293" FT /gene_synonym="SCE15.10c" FT /product="putative small integral membrane protein" FT /note="SCE15.10c, possible small integral membrane protein, FT len: 167aa; contains a possible membrane spanning FT hydrophobic region." FT /db_xref="UniProtKB/TrEMBL:Q9X885" FT /protein_id="CAB41279.1" FT /translation="MGDALWNTEVGPAEYSVADDRYRQAVLDQYKLCVEMADRVSARRN FT LTNTFFLSLNSAVVAVVAAVSGGALADASVPLLLAGLVILLVQCAAWYVMVRSYRQLNR FT AKYAVIGAFEERLPAFAYSRGEWGALGEGRDWRRYLPLTYVEQWVPVVFAGSYVTGFFA FT LVTR" FT CDS complement(17867..19213) FT /transl_table=11 FT /gene="SCO3294" FT /gene_synonym="SCE15.11c" FT /product="putative transferase" FT /note="SCE15.11c, possible transferase, len: 448aa; weak FT similarity to SW:MTRD_METMA FT N5-methyltetrahydromethanopterin coenzyme M FT methyltransferase from Methanosarcina mazei (250 aa) fasta FT scores; opt: 126, z-score: 151.3, E(): 0.41, (26.3% FT identity in 137 aa overlap). Contains TTA leucine codon in FT the N-terminal region - possible target for bldA FT regulation." FT /db_xref="GOA:Q9X886" FT /db_xref="UniProtKB/TrEMBL:Q9X886" FT /protein_id="CAB41280.1" FT /translation="MSRPQPGQSPDRLPEKPLPRWFPAALPVSVLVAVLWGPVYAAVLC FT GVAAVAVAYATTRKPELWHLAAGTGLCAAGVLAQAFAYYLILRDGSLGPHGSAAVLFLL FT GLQFFLHGRKVRRAAQLTLSALRRHREENGLLRAAEPLGERRPGARRVPFAMTSVFGAV FT VSGLGSLFLCFTLLALRDLLTTGGNPWWASLVVAALCAQAVLFIGLGNTILRTGVQYYD FT TVVSSPDDLAGRQYVLYLRSFRDDHRLSRPHRIPLAGAWLAAAVSLGQGEEERIADALS FT WAGPLVGVGAPGERVPRAGARRMYLPPDDWQRPVSTMMRGAALVVIVLGKGPGTLWEIR FT EAMRILPPERLLLLVPMKEKAYDEFRELAGDLAPGVLPAYRRSRALSSRVRGIIHFEPD FT WTARFVALRRPPPLEDPLVGSLDRAMWPAMVRLTELELERRADGRRGEA" FT misc_feature complement(19175..19177) FT /note="tta leucine codon. Possible target for bldA FT regulation." FT CDS complement(19317..19985) FT /transl_table=11 FT /gene="SCO3295" FT /gene_synonym="SCE15.12c" FT /product="putative oxidoreductase" FT /note="SCE15.12c, possible oxidoreductase, len: 222aa; FT similar to TR:O85762 (EMBL:AF075709) NADH dependent FMN FT reductase from Pseudomonas putida (200 aa) fasta scores; FT opt: 208, z-score: 241.1, E(): 4e-06, (35.7% identity in FT 129 aa overlap)." FT /db_xref="InterPro:IPR005025" FT /db_xref="UniProtKB/TrEMBL:Q9X887" FT /protein_id="CAB41281.1" FT /translation="MKLVVVSAGLSVPSSTRLLADRLAAVAAPAATAPEPGPADVRVIE FT LRDLAVEIAHTFTNGFPAPALADAFAEVAAADGLIVVTPVFSASYSGLFKSFFDALSVT FT DEDALTGKPVLIAATGGTGRHSLVLEHALRPLFAYLKAVIVPTGVYAASEDWGAEGLDA FT RIERAATELAALMSGLSGSARASGPSAGRPLPKRDSFEEVTPFAERLAALSVPGPSPAP FT " FT CDS complement(19982..21085) FT /transl_table=11 FT /gene="SCO3296" FT /gene_synonym="SCE15.13c" FT /product="putative oxidoreductase" FT /note="SCE15.13c, possible oxidoreductase, len: 367aa; some FT similarity to TR:CAA77275 (EMBL:Y18729) F420-dependent FT alcoholdehydrogenase from Methanoculleus thermophilicus FT (330 aa) fasta scores; opt: 211, z-score: 252.,1 E(): FT 9.9e-07, (29.0% identity in 183 aa overlap)." FT /db_xref="GOA:Q9X888" FT /db_xref="InterPro:IPR016048" FT /db_xref="UniProtKB/TrEMBL:Q9X888" FT /protein_id="CAB41282.1" FT /translation="MQFGIFTVGDVTPDPTTGRTPTERERIKAMVAIALKAEEVGLDVF FT ATGEHHNPPFVPSSPTTMLGYVAARTERLVLSTSTTLITTNDPVKIAEDFAMLQHLADG FT RVDLMMGRGNTGPVYPWFGKDIREGINLAVENYNLLHRLWREDVVNWEGKFRTPLQGFT FT STPRPLDGVAPFVWHGSIRSPEIAEQAAYYGDGFFHNNIFWPADHTKRMIELYRARYAH FT YGHGTPEQAIVGLGGQVFMRKNSQDAVREFRPYFDEAPVYGHGPSLEDFTAQTPLTVGS FT PQQVIEKTLAFRDYAGDYQRQLFLMDHAGLPLKTVLEQLDLLGEEVVPVLREEFAKNRP FT ADVPDAPTHASLLASRKGAPTEEGARA" FT CDS 21181..21519 FT /transl_table=11 FT /gene="SCO3297" FT /gene_synonym="SCE15.14" FT /product="putative membrane protein" FT /note="SCE15.14, putative membrane protein, len: 112 aa; FT similar to others e.g. SW:YQ09_MYCTU (EMBL:Z80225) FT Mycobacterium tuberculosis hypothetical protein (110 aa) FT fasta scores; opt: 597, z-score: 741.6, E(): 0, (73.1% FT identity in 108 aa overlap) Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q9X889" FT /db_xref="InterPro:IPR003844" FT /db_xref="UniProtKB/Swiss-Prot:Q9X889" FT /protein_id="CAB41283.1" FT /translation="MLVLRSAALFVVAALFEIGGAWLVWQGVREQRGWLWAAGGVLALG FT AYGFVATFQPDAHFGRILAAYGGIFVTGSILWGVVADGYRPDRWDIAGALVCLAGMALI FT MWAPRNGG" FT CDS 21589..22371 FT /transl_table=11 FT /gene="SCO3298" FT /gene_synonym="SCE15.15" FT /product="putative oxidoreductase" FT /note="SCE15.15, possible oxidoreductase, len: 260aa; FT similar to many egs. SW:YV10_MYCTU putative oxidoreductase FT from Mycobacterium tuberculosis (251 aa) fasta scores; opt: FT 826, z-score: 880.1, E():0, (57.2% identity in 243 aa FT overlap) and TR:O54197 (EMBL:AJ000671) FT clavulanate-9-aldehyde reductase from Streptomyces FT clavuligerus (247 aa) fasta scores; opt: 493, z-score: FT 530.5, E(): 3.1e-22, (39.8% identity in 249 aa overlap). FT Contains Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase." FT /db_xref="GOA:Q9X890" FT /db_xref="HSSP:1FJH" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9X890" FT /protein_id="CAB41284.1" FT /translation="MATAAAAPSAASRIAVVTGASSGIGAATARQLAAAGYRVVLTARR FT KDRIEALAGEIEAAGHKATAYPLDVTDREAVDEFATAFKTVGVLVNNAGGALGADPVAT FT GDPDDWRRMYETNVIGTLNLTQALLPKLEASGDGTVVVVSSTAGLSTYEGGAGYVAAKH FT GEHVLAETLRLEIVGRPVRVVEIAPGMVKTDEFALTRFAGDQDKAAKVYQGVAAPLTAD FT DVADTITWAVTRPAHVNIDLLVVRPRAQASNTKVHREA" FT misc_feature 21625..22170 FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 192.70, E-value 5.7e-54." FT CDS complement(22405..23598) FT /transl_table=11 FT /gene="SCO3299" FT /gene_synonym="SCE15.16c" FT /product="conserved hypothetical protein" FT /note="SCE15.16c, unknown, len: 397aa; similar to many e.g. FT SW:RTCB_ECOLI hypothetical protein from Escherichia coli FT (408 aa) fasta scores; opt: 809, z-score: 903.2, E(): 0, FT 46.8% identity in 408 aa overlap. Contains Pfam match to FT entry PF01139 UPF0027, Uncharacterized protein family FT UPF0027." FT /db_xref="InterPro:IPR001233" FT /db_xref="UniProtKB/TrEMBL:Q9X891" FT /protein_id="CAB41285.1" FT /translation="MSYVEMPGAKVPIRMWADPATVEEGALQQLRNVATLPWIKGLAVM FT PDVHYGKGATVGSVIAMRGAVCPAAVGVDIGCGMSAVKTSLTANDLPGDLSRLRSKIEQ FT AIPVGRGMHDSPLEPGRFHGLATGGWDDFWGRFDGVAEAVKFRHERAGKQMGTLGGGNH FT FVEVCTDTTGSVWLMLHSGSRNIGKELAEHHIGVAQKLPHNQGLVDRDLAVFVADTPQM FT AAYRNDLFWAQEYAKYNRTLMMALLKDVVRKEFKKAKPIFEQEISAHHNYVAEERYDGM FT DLLVTRKGAIRAGSGDFGIIPGSMGTGSYIVKGLGNAKSFNSASHGAGRRMSRNAAKRR FT FSTKDLEEQTRGVECRKDSGVVDEIPGAYKPIDQVIDQQRDLVEVVAKLKQVVCVKG" FT misc_feature complement(22408..23598) FT /note="Pfam match to entry PF01139 UPF0027, Uncharacterized FT protein family UPF0027 , score 317.70, E-value 1.4e-91." FT CDS 23698..24681 FT /transl_table=11 FT /gene="SCO3300" FT /gene_synonym="SCE15.17" FT /product="putative secreted serine-rich protein" FT /note="SCE15.17, possible secreted serine-rich protein, FT len: 320aa; contains possible N-terminal signal sequence." FT /db_xref="UniProtKB/TrEMBL:Q9X892" FT /protein_id="CAB41286.1" FT /translation="MRYTLSPGDAPARQANNQRGHWSTDHSHTGERSRTVQRKAYVPGV FT AALLAALLAGCTGGSGGGATADDSNPGQPGVATEAAEPGKYRTLPEPCAVVGHKALDTL FT LPGIEEIADEEQRARAYSGEPTLAYDTDRKVGCRWKVESAEATDHLFVDFERVVSYDGS FT VSDAGEAEELFAQQVEAADLPEPVVSESGSAASDSPSGSPSSSSGKSGEPGESGEPAGG FT AGGTPSSSASAPSSSPSSSSTASPAEVQPRLLDDLGDEAFVDDALSSSGSTAKRRTVTV FT AFRTSNVMVTIEYAEQSATLGVVPDSEEMQDMARNLASQLADSLGG" FT CDS 24814..25665 FT /transl_table=11 FT /gene="SCO3301" FT /gene_synonym="SCE15.18" FT /product="putative secreted protein" FT /note="SCE15.18, possible secreted protein, len: 283aa; FT contains possible N-terminal signal sequence." FT /db_xref="UniProtKB/TrEMBL:Q9X893" FT /protein_id="CAB41287.1" FT /translation="MQLRAQRDQRDPQAKRAKRLTRVLVGAAAVPVMLVAAGCSSDSGS FT DDGKDKAAEESAASKSASPSPTVKAAAYGKLPEPCSVVSKKTLDDLVPKADSGKEGSSN FT DTAMRAGCSWDSLDDNGVKGSQFRWLSVSMLRFESDVTRGEGEKLAHDYYLKQLKDAQP FT AQGAKSLKTAPVSRTGNEASVVSYDLKKKEGTFKQQTVVARVENVVVTLDFNGAGLAGD FT KTPDAGDLVKDAQKAAKEAVAAVMKANDTSAGGTPSGTPQGSGSPSKPASETSSKAPSK FT SS" FT CDS 25755..27056 FT /transl_table=11 FT /gene="SCO3302" FT /gene_synonym="SCE15.19" FT /product="putative integral membrane protein" FT /note="SCE15.19, possible integral membrane protein, len: FT 433aa; contains possible membrane spanning hydrophobic FT regions." FT /db_xref="UniProtKB/TrEMBL:Q9X894" FT /protein_id="CAB41288.1" FT /translation="MAAPLQLTRTHRVLIGLVVFGAVIIAGIGFAGSYAAVRELALKKG FT FGNFSYVFPIGIDAGICVLLALDLLLTWIRIPFPLLRQTAWLLTAATIAFNGAAAWPDP FT LGVGMHGVIPILFVVSVEAARHAIGRIADITADKHMEGVRLTRWLLSPVPTFLLWRRMK FT LWELRSYEQVIKLEQERLVYRARLRSRFGRAWRRKAPVESLMPLRLARYGVPLAQTGPA FT GLAAAGIEPALLPPVPRQLQETDPQAPAGEQRAELVKGPEADRPRPAEPSGPEGPSPQG FT AGEEDGPEQSPWFNTRQVAYQGGYDPSYDPGEQYAQWYEEQQQADEYRDQYEEEPPLQE FT PSPEETGSFPIPVVPGRTRELGEGAGPAEPAPTEEDYYTVFRKSIDGSYPTVAQFRGDV FT EATFGVPLAPREADRMVKAFSERHMRELQEEHIA" FT stem_loop 27250..27295 FT /note="Perfect inverted repeat 20/20 with 6 base loop." FT CDS complement(27309..29051) FT /transl_table=11 FT /gene="SCO3303" FT /gene_synonym="SCE68.01c" FT /gene_synonym="SCE15.20c" FT /product="putative lysyl-tRNA synthetase" FT /note="SCE68.01c, possible lysyl-tRNA synthetase, len: >76 FT aa; similar to SW:SYK_METMP (EMBL:AF009824) LysS, FT Methanococcus maripaludis lysyl-tRNA synthetase (533 aa), FT fasta scores; opt: 114 z-score: 145.7 E(): 0.86, 44.7% FT identity in 38 aa overlap and to many hypothetical FT lysyl-tRNA synthetases. The remainder of this CDS is FT SCE15.20c, partial CDS, possible lysyl-tRNA in FT EMBL:AL049707" FT /note="SCE15.20c, partial CDS, possible lysyl-tRNA FT synthetase, len: >545aa; similar to many eg. SW:SYK_METJA FT lysyl-tRNA synthetase from Methanococcus jannaschii (530 FT aa) fasta scores; opt: 419, z-score: 468.7, E(): 8.5e-19, FT (29.2% identity in 559 aa overlap). Contains" FT /db_xref="GOA:Q9X895" FT /db_xref="HSSP:1IRX" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/Swiss-Prot:Q9X895" FT /protein_id="CAD55312.1" FT /translation="MPIVAQSTETTDWVSRFADEVIAESERRAPGKPGVVVASGLSPSG FT PIHLGNLREVMTPHLVADEVRRRGHEVRHLISWDDYDRYRKVPAGVPGVDESWAEHIGK FT PLTSVPAPKGSPHPNWAEHFKAAMVDSLAEMGVEFDGISQTAQYTSGVYREQILHAMKH FT RRDIDAILDQYRTKKAPAKKSQKPLDEAELEAAEGSGAAAEDDGSSGSAGYFPYKPYCG FT NCEKDLTTVTAYDDDSTELTYACTACGFSETVRLSEFNRGKLVWKVDWPMRWAYEGVVF FT EPSGVDHSSPGSSFQVGGQIVGIFGGEQPIGPMYAFVGISGMAKMSSSKGGVPTPADAL FT KIMEPQLLRWLYARRRPNQSFKIAFDQEIQRLYDEWDRLDAKVADGSALPADAAAHARA FT VGTAAGELPRTPRPLPYRTLASVADITAGHEDQALRILGELDPANPIASLDEARPRYDK FT AEAWINTHVPADQRTIVRQEPDAELLKSLDEPSRQSLRLLLDGLADHWSLDGLTHHVYG FT VPKVQAGFPADATPKELPPEIKTAQRTFFALLYHLLVGRDTGPRLPTLLLAVGQDRVRT FT LLGE" FT misc_feature complement(28896..28925) FT /note="PS00178 Aminoacyl-transfer RNA synthetases class-I FT signature" FT RBS complement(29054..29057) FT /note="possible RBS" FT CDS 29225..30985 FT /transl_table=11 FT /gene="SCO3304" FT /gene_synonym="SCE68.02" FT /gene_synonym="argS" FT /product="putative arginyl-tRNA synthetase" FT /note="SCE68.02, argS, probable arginyl-tRNA synthetase, FT len: 586 aa; similar to many e.g. SW:SYR_ECOLI FT (EMBL:X15320), argS, Escherichia coli arginyl-tRNA FT synthetase (577 aa), fasta scores; opt: 1415 z-score: FT 1562.9 E(): 0, 43.8% identity in 587 aa overlap. Contains FT Pfam match to entry PF00750 tRNA-synt_1d, tRNA synthetases FT class I (R) and PS00178 Aminoacyl-transfer RNA synthetases FT class-I signature" FT /db_xref="GOA:Q9WX29" FT /db_xref="HSSP:1IQ0" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/Swiss-Prot:Q9WX29" FT /protein_id="CAB45338.1" FT /translation="MASVTSLSDSVQQHLASALTATRPEAAGADPLLRRSDRADYQANG FT ILALAKKTKANPRELAAEVVARITTGDELIEDVEVSGPGFLNITVADRAITANLAARLA FT DGERLGVPLKQDAGTTVVDYAQPNVAKEMHVGHLRSAVIGDALRSMLDFTGEKTIGRHH FT IGDWGTQFGMLIQYLFEHPGELAPAGDIDGEQAMSNLNRVYKASRAVFDTDEEFKERAR FT RRVVALQSGDKETLDLWQQFVDESKVYFYSVFEKLDMEIRDEEIVGESAYNDGMPETAR FT LLEEMGVAVRSEGALVVFFDEIRGKDDQPVPLIVQKADGGFGYAASDLTAIRNRVQDLH FT ATTLLYVVDVRQSLHFRMVFETARRAGWLGDEVTAHNMGYGTVLGADGKPFKTRAGETV FT RLEDLLDEAVQRAAEVVREKARDLTEDEIQERAAQVGIGAVKYADLSTSPNRDYKFDLD FT QMVSLNGDTSVYLQYAYARIQSILRKAGEVRPAAHPELALHEAERALGLHLDAFGPTVF FT EAAAEYAPHKLAAYLYQLASLYTTFYDKCPVLKAETPEQVENRLFLCDLTARTLHRGMA FT LLGIRTPERL" FT misc_feature 29237..30982 FT /note="Pfam match to entry PF00750 tRNA-synt_1d, tRNA FT synthetases class I (R), score 499.40, E-value 2.7e-146" FT misc_feature 29603..29638 FT /note="PS00178 Aminoacyl-transfer RNA synthetases class-I FT signature" FT RBS 31111..31114 FT /note="possible RBS" FT CDS 31121..32446 FT /transl_table=11 FT /gene="SCO3305" FT /gene_synonym="SCE68.03" FT /product="putative membrane protein" FT /note="SCE68.03, possible membrane protein, len: 441 aa; FT unknown function, weakly similar to TR:O66257 FT (EMBL:AB010415) Actinobacillus actinomycetemcomitans FT integral membrane acetyltransferase (344 aa), fasta scores; FT opt: 259 z-score: 247.1 E(): 1.9e-06, 24.2% identity in 360 FT aa overlap. Contains hydrophobic, possible FT membrane-spanning regions" FT /db_xref="GOA:Q9WX28" FT /db_xref="InterPro:IPR002656" FT /db_xref="UniProtKB/TrEMBL:Q9WX28" FT /protein_id="CAB45339.1" FT /translation="MRIGKASAGSKPADAPRGSVGQQAPRGRIGILDGLRLCAALMVVL FT YHYVAFGGGWEGSQAQLFPVLFRPSAYGWLGVELFFMISGFVICMSSWGRSVSHFFTSR FT VIRLFPAYWLAIAVTTAVVFFMPGGITPLPWRDLLVNLTMLQRPMGVDEVEGVYWTLWA FT EMRFYLLFALVVWRGVTYRRVVVFCCVWATAAVVAKRGEANPISDLVMAQDCWFFIAGL FT AFYLMYRFGQNLLLWGMIAFCFAMGNYTAMTTWRATLDNVGDNVPDWGVAVVLTVFFVT FT MAGVALGWFRRVDWRWLPTAGALTYPLYLLHESIGWEVFHRYQYTVNQWVLVGGTLAGV FT LVLSYLVHRLVEKPMSKRLKTGLAKAFDQIRAEGATHHERPPTPVGPVRPEPGPPGSGP FT PGSAPLPQGSGPDLDSPTRTLRLPAAPPPASAAPPRSRPVSG" FT CDS complement(32379..33593) FT /transl_table=11 FT /gene="SCO3306" FT /gene_synonym="SCE68.04c" FT /product="putative aminotransferase" FT /note="SCE68.04c, possible aminotransferase, len: 404 aa; FT similar to TR:Q56232 (EMBL:D38459), aspC, Thermus aquaticus FT aspartate aminotransferase (385 aa), fasta scores; opt: 379 FT z-score: 433.6 E(): 7.9e-17, 28.9% identity in 370 aa FT overlap and to many hypothetical aminotransferases. Similar FT to many from S.coelicolor e.g. SCH10.36 (EMBL:AL049754) FT probable aspartate aminotransferase (396 aa) (33.2% FT identity in 404 aa overlap). Alternative start codons are FT present at codons 3 and 7. Contains Pfam match to entry FT PF00155 aminotran_1, Aminotransferases class-I" FT /db_xref="GOA:Q9WX27" FT /db_xref="HSSP:1J32" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:Q9WX27" FT /protein_id="CAB45340.1" FT /translation="MTVTENVPAATASLPPLAARARSIGGSPVRDILAVTARPEVINFA FT GGLPAPELFDAEGIAAAYRDVLAETPARALQYSTTEGEPALRAALAARTSARGLATDAD FT DILVTTGSQQALSLLATALLEPGDTVLVERPCYLAALQAFGFAGARVVAVPGDEHGIDP FT GALEELVVRERPKLLYTVPTFSNPTGRTVPAARRAAVAEVAGRCGLWIVEDDPYGELRF FT EGERVPWIASYEGARDRTVLLGSFSKVMAPGLRLGWLRAPAELRRACAVAKQAADLHTP FT TVNQLAAARYLADRDLDAHVARVAAVYGERRDAMLAGLADALPAGSVWTRPEGGMFLWA FT RLPQGYDTTALLPEVVRHDVAYVPGAPFHAGEPDRATLRLCFVTQTPDEIAEGLRRLGE FT GLRAA" FT misc_feature complement(32385..33554) FT /note="Pfam match to entry PF00155 aminotran_1, FT Aminotransferases class-I, score 25.10, E-value 6.9e-12" FT CDS complement(33685..34587) FT /transl_table=11 FT /gene="SCO3307" FT /gene_synonym="SCE68.05c" FT /product="conserved hypothetical protein" FT /note="SCE68.05c, conserved hypothetical protein, len: 300 FT aa; unknown function, similar to others from S.coelicolor FT e.g. TR:O86541 (EMBL:AL031350), SC1F3.04, hypothetical FT protein (261 aa), fasta scores; opt: 791 z-score: 916.0 FT E(): 0, 48.9% identity in 262 aa overlap" FT /db_xref="InterPro:IPR006764" FT /db_xref="UniProtKB/TrEMBL:Q9WX26" FT /protein_id="CAB45341.1" FT /translation="MPGDALSQDPAELRRRIDSSKAHPARVYDVFLGGKDHYPADLAAA FT AAGLAANPRGYLDVRHNRDFLRRAVTALAREDGIRQFLDIGTGLPTAENVHQIAQRIAP FT ESRVVYVDDDPVVLAHARALLTSGPEGRTDYIDADLKSPAQILEQAAATLDFDQPVALC FT LVAILHFVEDEEAYPIVRELMDALPAGSRLVLSHLTEDLNPENIRAVQRTYTERGFTFV FT LRSRKDVERFFTEAGLELAEPGVVPVHHWRPDHAAPVPEQPEESYLAGLDDIEKVRYRD FT INDVTDADINVYGGLGAKG" FT CDS complement(34691..36085) FT /transl_table=11 FT /gene="SCO3308" FT /gene_synonym="SCE68.06c" FT /product="putative DNA-binding protein" FT /note="SCE68.06c, probable DNA-binding protein, len: 464 FT aa; similar to TR:Q9AK04 (EMBL:AL512944) Streptomyces FT coelicolor hypothetical protein SC8D11.15c, 471 aa; fasta FT scores: opt: 428 Z-score: 331.6 E(): 7.7e-11; 40.377% FT identity in 478 aa overlap; probable CDS suggested by FT positional base preference, GC frame analysis and amino FT acid composition. Contains a hydrophobic, possible FT membrane-spanning region, followed by a low-complexity FT proline- and serine-rich region from aa 210 to 250 approx. FT Contains probable helix-turn-helix motif at aa 20-41 (Score FT 1605, +4.65 SD)" FT /db_xref="GOA:Q9WX25" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q9WX25" FT /protein_id="CAB45342.1" FT /translation="MAGDDFAALLRELKERSGLSYGALGKRLHMSGSTLHRYVSGEVVP FT VEFAPVERLARVCRATPDELLELHRRWIRADALRGVKKDEAEGAEGSDGGETAEGAEGA FT AADSTASARAPSAAPPVPDTTPVPATPVPAAPVMATPVPVTPDATPAPGSVPPARDASG FT PARRRVPRAALYAATGVVAVSAAVALVANLVASPDDDGRHGPAGAVAQTSASVSGTATG FT PGSTSPGPSASTSAPSASASVSGTSSASPSRPATAAPSRQAPAGPPLTVSTTPYYWEVP FT CDHAFLVDRSPKNVPKPPPQQGAVGWAAPLKAVSANRQEVVLTVQGTGPETVVLEDLHV FT RVVSSGPALDWNQYVMGNGCGGQVDTASFDVSLDLGTPTAVPIGGQRDFPYSVTESDTE FT VFHATAHTSGQDVSWYLELEWSSGGRHGMTRVDDHGKPFRTSASRDDSYYAYPLGSDHW FT ELVEGG" FT RBS complement(36090..36094) FT /note="possible RBS" FT CDS complement(36228..36605) FT /transl_table=11 FT /gene="SCO3309" FT /gene_synonym="SCE68.07c" FT /product="hypothetical protein" FT /note="SCE68.07c, hypothetical protein, len: 125 aa; FT unknown function, probable CDS suggested by GC frame FT analysis and amino acid composition" FT /db_xref="UniProtKB/TrEMBL:Q9WX24" FT /protein_id="CAB45343.1" FT /translation="MLEPEAEPEPEPDALSLPAEPFEAVDPFEPVEPVDSFEPVDPSTP FT FALPAGWTLFPSADAEAVESGAGEPVSSSPSQAVRESAASATVVAANRRVRVMRRADME FT VLLRKWGVEASRSTVLRERLL" FT misc_feature complement(36526..38681) FT /note="sequence corresponding to EMBL:U19249" FT RBS complement(36621..36624) FT /note="possible RBS" FT CDS 36787..37041 FT /transl_table=11 FT /gene="SCO3310" FT /gene_synonym="SCE68.08" FT /product="hypothetical protein" FT /note="SCE68.08, hypothetical protein, len: 84 aa; unknown FT function, probable CDS suggested by positional base FT preference, GC frame analysis and amino acid composition" FT /db_xref="UniProtKB/TrEMBL:Q9WX23" FT /protein_id="CAB45344.1" FT /translation="MPPVAKSSKPQSLTTLAPGESGYAGVRLSSGDGSGENGYDANTLT FT IPFEDGSIATVKLPSGGVYVDTALMVTYWQTDASNALEY" FT CDS complement(37100..38092) FT /transl_table=11 FT /gene="SCO3311" FT /gene_synonym="SCE68.09c" FT /gene_synonym="hemB" FT /product="delta-aminolevulinic acid dehydratase" FT /note="SCE68.09c, hemB, delta-aminolevulinic acid FT dehydratase, len: 330 aa; previously sequenced as FT SW:HEM2_STRCO (EMBL:U19249) (330 aa). Contains probable FT coiled-coil from 218 to 252 (35 residues) (Max score: FT 1.530, probability 0.97). Contains Pfam match to entry FT PF00490 ALAD, Delta-aminolevulinic acid dehydratase and FT PS00169 Delta-aminolevulinic acid dehydratase active site" FT /db_xref="GOA:P54919" FT /db_xref="HSSP:1B4K" FT /db_xref="InterPro:IPR013785" FT /db_xref="UniProtKB/Swiss-Prot:P54919" FT /protein_id="CAB45345.1" FT /translation="MTTYGSFPGARPRRLRTTPVMRRMVAETRLHPADFILPAFVREGV FT SEPVPIAAMPGVVQHTRDTLKKAAAEAVEAGVSGIMLFGVPEDGKKDAAGTAGTDPDGI FT LQVALRDVRAEVGDELLVMSDLCLDEFTDHGHCGVLDGQGRVDNDATLERYAEMAQVQA FT DAGAHVVGPSGMMDGQIGVIRDALDQIGREDVAILAYTAKYASAFYGPFREAVGSSLKG FT DRKTYQQDSANARESLRELALDLEEGADMVMVKPAGPYLDILAKVAEASDVPVAAYQIS FT GEYSMIEAAAEKGWIDRDRAILESLTGIKRAGARNILTYWATEVARTLR" FT misc_feature complement(37127..38032) FT /note="Pfam match to entry PF00490 ALAD, FT Delta-aminolevulinic acid dehydratase, score 626.50, FT E-value 1.5e-184" FT misc_feature complement(37313..37351) FT /note="PS00169 Delta-aminolevulinic acid dehydratase active FT site" FT CDS 38616..39026 FT /transl_table=11 FT /gene="SCO3312" FT /gene_synonym="SCE68.10" FT /product="conserved hypothetical protein" FT /note="SCE68.10, hypothetical protein, len: 136 aa; unknown FT function, probable CDS suggested by positional base FT preference, GC frame analysis and amino acid composition. FT Similar to TRNEW:CAC46514 (EMBL:AL591789) hypothetical FT protein SMC04265 from Rhizobium meliloti (Sinorhizobium FT meliloti) (147 aa) fasta scores; opt: 380, Z-score: 458.7, FT E(): 6.5e-18, 46.875% identity (47.244% ungapped) in 128 aa FT overlap." FT /db_xref="InterPro:IPR019587" FT /db_xref="UniProtKB/TrEMBL:Q9WX22" FT /protein_id="CAB45346.1" FT /translation="MNSTGRASRHLGIHIDRTATDVYAYASDPANLPAWAHGLGGTIER FT VADAWIADSSPLGRVKVTFVPRNDLGVLDHHVTLPSGETVYNPVRVIADGTASEVVFTL FT RRQPGTTDADFERDAGMVAADLARLKELLESA" FT CDS complement(39023..39940) FT /transl_table=11 FT /gene="SCO3313" FT /gene_synonym="SCE68.11" FT /product="hypothetical protein" FT /note="SCE68.11c, conserved hypothetical protein, len: 305 FT aa; unknown function, N-terminal half similar to FT hypothetical proteins from Mycobacterium tuberculosis, FT Mycobacterium paratuberculosis and Streptomyces lividans, FT e.g. SW:Y08L_MYCTU (EMBL:Z77137) Mycobacterium tuberculosis FT hypothetical protein (149 aa), fasta scores; opt: 297 FT z-score: 354.1 E(): 2.1e-12, 42.7% identity in 124 aa FT overlap" FT /db_xref="InterPro:IPR004378" FT /db_xref="UniProtKB/TrEMBL:Q9WX21" FT /protein_id="CAB45347.1" FT /translation="MPTSFHQSVIDEFRANEGKVGGPFEGGDLLLLTTTGARSGASRTT FT PLGYVRHGESLLVVGSNLGGPRHPGWYYNLLAHPLVRVEVGAAGFEALAVPAEGERREE FT LFAHVVREAPGYGDYQAGTSRPLPVVVLEQAEPEEWVGRPREVRTLADKLVEVHTWLRG FT QLRQVRAEVEAHFAAPGAAGAPPSLGLQIRQRCLAFCQVLEFHHDSEDGHLFPGTARHH FT PRLAPVFDRLAEEHRTVARVQGELAALLAGVSVAEPGRFRRELAAMSAELNAHLDHEEE FT VLLPLLADVPWPPVAPSAGPPTAR" FT RBS complement(39952..39956) FT /note="possible RBS" FT CDS complement(40230..41186) FT /transl_table=11 FT /gene="SCO3314" FT /gene_synonym="SCE68.12c" FT /product="putative dehydrogenase" FT /note="SCE68.12c, possible dehydrogenase, len: 318 aa; FT weakly similar to SW:QOR_CAVPO (EMBL:M26936) Cavia FT porcellus quinone oxidoreductase (329 aa), fasta scores; FT opt: 301 z-score: 320.4 E(): 1.6e-10, 27.6% identity in 326 FT aa overlap. Similar to TR:Q53927 (EMBL:X62373) ORF2 from FT S.coelicolor actVI locus (329 aa) (33.7% identity in 329 aa FT overlap). Contains Pfam match to entry PF00107 adh_zinc, FT Zinc-binding dehydrogenases" FT /db_xref="GOA:Q9WX20" FT /db_xref="HSSP:1PQW" FT /db_xref="InterPro:IPR013154" FT /db_xref="UniProtKB/TrEMBL:Q9WX20" FT /protein_id="CAB45348.1" FT /translation="MGEMKAVLFDRYGPPEVLYVGRRPVPAIGPDEVLVRVRAAGVNGG FT DLHDRTGKVRLVTGRAFPKGCGIDFAGEVAGVGASVRGVREGRRVWGLLGRRTGSMAEY FT VAVSPRRIAPAPDNLTPEEAVSLLAGATTALTALRDKAALQPGERLLVRGGSGGVGSVA FT VQVGRVLGARVVALAGGRNLDFVRGLGAEEALDHRTTALSALGRFDVVLDTVGTEQARV FT RRLLAPGGRMVAVAPDLDRPLAWLGTVLGSAVHGKGRIRFFSGNPDSALLAEAARLAEH FT GDIVPVVDTVHPLDGVADAQRALAAGGVRGKHVVRVR" FT misc_feature complement(40239..41159) FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score 5.70, E-value 1.3e-09" FT CDS 41315..42007 FT /transl_table=11 FT /gene="SCO3315" FT /gene_synonym="SCE68.13" FT /product="putative transcriptional regulator" FT /note="SCE68.13, probable transcriptional regulator, len: FT 230 aa; similar to TR:O53612 (EMBL:AL021428) Mycobacterium FT tuberculosis putative transcriptional regulator (189 aa), FT fasta scores; opt: 315 z-score: 346.2 E(): 5.8e-12, 35.5% FT identity in 172 aa overlap. Weak similarity to TR:O54180 FT (EMBL:AL021411), SC7H1.22, S.coelicolor probable FT transcriptional regulator (203 aa) (34.4% identity in 154 FT aa overlap). Contains probable helix-turn-helix motif at aa FT 50-71 (Score 1594, +4.62 SD). Contains Pfam match to entry FT PF00440 tetR, Bacterial regulatory proteins, tetR family FT (weak match)" FT /db_xref="GOA:Q9WX19" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9WX19" FT /protein_id="CAB45349.1" FT /translation="MPDQPSHNPAEHTTGEAPAPDALRADARRNRERVLEAAREVFSAR FT GVDAPMSAVARRAGVGVATLYRRFPTRSSLVAAAFDDQLTVCAAAFDEALADPDPGHGL FT YTLLRKVCTTLVTDRGFETVFMAGFPASLDYDRERACAEERLAHLVRRARDAGRLREDF FT SPADIPLLLLAVSGLASQPPETAVPAAHRLLTYLFQSFQADPPPRPAPLPPAPTLDLSG FT LHRPAERP" FT misc_feature 41414..41551 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 21.00, E-value FT 0.00045" FT CDS complement(42030..42806) FT /transl_table=11 FT /gene="SCO3316" FT /gene_synonym="SCE68.14c" FT /product="putative dehydrogenase" FT /note="SCE68.14c, probable dehydrogenase, len: 258 aa; FT similar to many e.g. SW:DHG3_BACME (EMBL:D10625), gdhIII, FT Bacillus megaterium glucose 1-dehydrogenase III (261 aa), FT fasta scores; opt: 424 z-score: 446.0 E(): 1.6e-17,32.4% FT identity in 253 aa overlap. Similar to many others from FT S.coelicolor e.g. TR:O88068 (EMBL:AL031541), SCI35.33c, FT probable dehydrogenase (260 aa) (33.5% identity in 254 aa FT overlap). Contains Pfam matches to entry PF00106 adh_short, FT short chain dehydrogenase and entry PF00678 adh_short_C2, FT Short chain dehydrogenase/reductase C-terminus. Contains FT PS00061 Short-chain dehydrogenases/reductases family FT signature" FT /db_xref="GOA:Q9WX18" FT /db_xref="HSSP:1GZ6" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9WX18" FT /protein_id="CAB45350.1" FT /translation="MTGLGRLDGKRTLVIGGGGAGIGRSIVRSCAAAGAAVAVADVDAA FT RATEAADELRAAGHVAHALSGDVRSREQLEDVIVGAADRLGGLDVLITVVGGQVAFVPA FT VRLHEMADADWDTVYELNLRYVARAVRRVLRLFLEQGTGGNIVGIGSVTGFMAAPMQAG FT YGAAKAGLHSLARTVAAEYAADGIRMNVVAGGAISTAVNAGPSDAWVPEIPAGRYGTSE FT EMAAAAVYLASDESRYVTGQQIVLDGGVSVRGPFPE" FT misc_feature complement(42069..42161) FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 46.70, FT E-value 5.2e-10" FT misc_feature complement(42207..42776) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 156.10, E-value 6.1e-43" FT misc_feature complement(42270..42356) FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT RBS complement(42811..42815) FT /note="possible RBS" FT stem_loop 42972..43127 FT /note="stem is 26/28 bp (92%) matches, 0 gaps; loop is 100 FT bp" FT CDS complement(43073..44770) FT /transl_table=11 FT /gene="SCO3317" FT /gene_synonym="SCE68.15c" FT /product="putative uroporphyrin-III FT C-methyltransferase/uroporphyrinogen-III synthase" FT /note="SCE68.15c, possible uroporphyrin-III FT C-methyltransferase/uroporphyrinogen-III synthase, len: 565 FT aa; similar to many e.g. SW:HEM4_CLOJO (EMBL:D28503), hemD, FT Clostridium josui porphyrin biosynthesis probable FT bifunctional protein (504 aa), fasta scores; opt: 519 FT z-score: 562.5 E(): 5.2e-24, 29.8% identity in 533 aa FT overlap. The C-terminal half is similar to the FT monofunctional SW:HEM4_SYNP7 (EMBL:X70966) Synechococcus FT sp. uroporphyrinogen-III synthase (264 aa) (29.7% identity FT in 263 aa overlap). May be involved in cysteine FT biosynthesis and/or porphyrin biosynthesis. Contains Pfam FT match to entry PF00590 TP_methylase, Tetrapyrrole FT (Corrin/Porphyrin) Methylases and PS00839 Uroporphyrin-III FT C-methyltransferase signature 1" FT /db_xref="GOA:Q9WX17" FT /db_xref="HSSP:1PJT" FT /db_xref="InterPro:IPR003754" FT /db_xref="UniProtKB/TrEMBL:Q9WX17" FT /protein_id="CAB45351.1" FT /translation="MSPTTLPAGPEHGHVTFLGAGPGDPGLLTLRAVEALAHADVLVAE FT HEVLDVVRTHAKQGVSEVHTDADPSDPGTGAPQLTVVDGASTTFGAPAVRDAAHLVMEA FT ARGGRRVVRAVTGDPGLDAYAAEEMLACAAAGVPFEVVPGIANAVGVPAYAGVPLRDAE FT GADVRFVDARTASDRCWTEVGASDGTVVVSTTLDSVAAAAGELVSAGRKPDTPLTVTIA FT GTTTRQRTWTATLGTVAQTLKQAKVLPSPDGGRPVIAVVGERSSAARRDQLSWFESKPL FT FGWKVLVPRTKEQAASLSDQLRSYGAVPSEVPTIAVEPPRTPQQMERAVKGLVTGRYEW FT IAFTSVNAVKAVREKFEEYGLDARAFAGIKVAAVGEQTANALIAFGVKPDLVPSGEQSA FT AGLLEDWPPYDPVFDPIDRVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPA FT TTREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVM FT SPEPSVTKLAEALADFGLRRRAAALEAGDPVTRPSERRPGSRRRRSST" FT misc_feature complement(44054..44731) FT /note="Pfam match to entry PF00590 TP_methylase, FT Tetrapyrrole (Corrin/Porphyrin) Methylases., score 105.40, FT E-value 1.1e-27" FT misc_feature complement(44675..44719) FT /note="PS00839 Uroporphyrin-III C-methyltransferase FT signature 1" FT CDS complement(44767..45726) FT /transl_table=11 FT /gene="SCO3318" FT /gene_synonym="SCE68.16c" FT /gene_synonym="hemC" FT /product="putative porphobilinogen deaminase" FT /note="SCE68.16c, hemC, probable porphobilinogen deaminase, FT len: 319 aa; similar to many e.g. SW:HEM3_BACSU FT (EMBL:M57676), hemC, Bacillus subtilis porphobilinogen FT deaminase (314 aa), fasta scores; opt: 721 z-score: 807.5 FT E(): 0, 39.8% identity in 314 aa overlap. Contains Pfam FT match to entry PF01379 Porphobil_deam, Porphobilinogen FT deaminase" FT /db_xref="GOA:Q9WX16" FT /db_xref="HSSP:1PDA" FT /db_xref="InterPro:IPR000860" FT /db_xref="UniProtKB/Swiss-Prot:Q9WX16" FT /protein_id="CAB45352.1" FT /translation="MTEKALRLGTRRSKLAMAQSGQVADAVSQVTGRPVELVEITTYGD FT TSREHLAQIGGTGVFVAALRDALLRGEVDFAVHSLKDLPTAQHEGLVVAAIPEREDPRD FT VVVARDARKLTDLPRGARVGTGAPRRMAQLNAYARTHGMEIETVPIRGNVDTRIGYVRS FT GELDAVVLAAAGLNRVGRIDEVTDFLSVDTVLPAPGQGALAVECAADNASLIAALAELD FT DPFTRAAVTAERSLLAALEAGCSAPVGALADLLADGQTVKEMRLRGVVGTTDGSTLVQL FT STTGPVPETHEAALALGGELAAEMLAQGAAGLMGERAQ" FT misc_feature complement(44806..45711) FT /note="Pfam match to entry PF01379 Porphobil_deam, FT Porphobilinogen deaminase, score 352.60, E-value 4.2e-102" FT CDS complement(45723..47468) FT /transl_table=11 FT /gene="SCO3319" FT /gene_synonym="SCE68.17c" FT /product="putative glutamyl-tRNA reductase" FT /note="SCE68.17c, probable glutamyl-tRNA reductase, len: FT 581 aa; similar to many e.g. SW:HEM1_BACSU (EMBL:M57676), FT HemA, Bacillus subtilis glutamyl-tRNA reductase (455 aa), FT fasta scores; opt: 558 z-score: 588.2 E(): 1.9e-25, 36.3% FT identity in 300 aa overlap. Contains Pfam match to entry FT PF00745 GlutR, Glutaminyl-tRNA reductase and PS00747 FT Glutamyl-tRNA reductase signature" FT /db_xref="GOA:Q9WX15" FT /db_xref="HSSP:1GPJ" FT /db_xref="InterPro:IPR006151" FT /db_xref="UniProtKB/Swiss-Prot:Q9WX15" FT /protein_id="CAB45353.1" FT /translation="MSLLVVGLSHRSAPVSVLERASLNADAQLKLLQDTVAAEPAAEAA FT VLATCNRIELYADVDKFHAGVAELSTLLAQHSGVGLEELTPYLYVHYEDRAVHHLFSVA FT CGLDSMVVGEGQILGQIKDSLARAQDLHTAGRLLNDLFQQALRVGKRAHSETGIDRAGQ FT SLVTFGLEQLSAGADVEQWARGKKALVIGAGSMSSLAAATLARAGVAEIVVANRTFERA FT ERLALLLEEQYGQRLSEGDDTDVLARAVPMDAVPGELTRADVAVSCTGATGLVLTADSV FT AATVEGRTGAPAVEDTAVQETAVREAGETPLPGAGSAADENCPLDLSSVSSVPSGFSVM FT GEAAVAGMDAATLEQHGAWAAGGTAVDRTREAGRSGPEADAELIGALAATATRVGRIPE FT RRRPEPVAEAPRPQPVLFLLDLAMPRDVDAAVHRLAGVRLVDIESLADASADAPMAADV FT DMVRRIVADEVAAFGAAQRAAHITPTVVALRSMAADVVAGEIARLEGRLPGLDDKHRAE FT ITQTVKRVVDKLLHAPTVRVKQLAAEPGGAGYADALRTLFDLDQETVASVSRAENSTEK FT NRGPA" FT misc_feature complement(45789..47363) FT /note="Pfam match to entry PF00745 GlutR, Glutaminyl-tRNA FT reductase, score 236.80, E-value 3.1e-67" FT misc_feature complement(47103..47174) FT /note="PS00747 Glutamyl-tRNA reductase signature" FT CDS complement(47465..48241) FT /transl_table=11 FT /gene="SCO3320" FT /gene_synonym="SCE68.18c" FT /product="conserved hypothetical protein" FT /note="SCE68.18c, hypothetical protein, len: 258 aa; FT similar to P25 (EMBL:AF061257) Thermus aquaticus AT-rich FT DNA-binding protein (211 aa), fasta scores; opt: 529 FT z-score: 604.8 E(): 2.3e-26, 44.9% identity in 198 aa FT overlap. Also similar to hypothetical proteins from FT Bacillus subtilis TR:O05521 (EMBL:D88802), YdiH (215 aa) FT (40.9% identity in 198 aa overlap) and Bacillus halodurans FT (EMBL:AB013375), YdiH (211 aa) (42.9% identity in 198 aa FT overlap)" FT /db_xref="GOA:Q9WX14" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/Swiss-Prot:Q9WX14" FT /protein_id="CAB45354.1" FT /translation="MATGRAHRPATRSRGIPEATVARLPLYLRALTALSERSVPTVSSE FT ELAAAAGVNSAKLRKDFSYLGSYGTRGVGYDVEYLVYQISRELGLTQDWPVVIVGIGNL FT GAALANYGGFASRGFRVAALIDADPGMAGKPVAGIPVQHTDELEKIIQDDGVSIGVIAT FT PAGAAQQVCDRLVAAGVTSILNFAPTVLNVPEGVDVRKVDLSIELQILAFHEQRKAGEE FT AAADGAAPPVAARKQQRSTGSADQGPDGDVPAVMPA" FT CDS complement(48516..48821) FT /transl_table=11 FT /gene="SCO3321" FT /gene_synonym="SCE68.19c" FT /product="putative redoxin" FT /note="SCE68.19c, possible redoxin, len: 101 aa; similar to FT TR:O69271 (EMBL:Y09572), NrdH, Corynebacterium ammoniagenes FT NrdH-redoxin from a ribonucleotide reductase operon (75 FT aa), fasta scores; opt: 96 z-score: 145.6 E(): 0.88, 27.6% FT identity in 76 aa overlap. Also similar to SW:YV35_MYCTU FT (EMBL:Z77162) Mycobacterium tuberculosis hypothetical FT protein (97 aa) (33.3% identity in 75 aa overlap). Cys32 FT and Cys35 are conserved in similar proteins" FT /db_xref="InterPro:IPR012335" FT /db_xref="UniProtKB/TrEMBL:Q9WX13" FT /protein_id="CAB45355.1" FT /translation="MAGMSPLFRRKPTQPPEHSENHLVTLIRKPGCHLCDDAQLVVEKV FT CAELGVPWEGKDITEDRQLHDQYWEQIPVVLVDGRQHTFWRVNEERLRKVLTDQYK" FT CDS 49020..49916 FT /transl_table=11 FT /gene="SCO3322" FT /gene_synonym="SCE68.20" FT /product="putative membrane protein" FT /note="SCE68.20, putative membrane protein, len: 298 aa; FT unknown function, similar to TR:O33611 (EMBL:AB004855) FT Streptomyces cyaneus hypothetical protein (277 aa), fasta FT scores; opt: 463 z-score: 536.3 E(): 1.5e-22, 34.2% FT identity in 269 aa overlap. C-terminus similar to other FT hypothetical proteins e.g. SW:YV32_MYCTU (EMBL:Z77162) from FT Mycobacterium tuberculosis (373 aa) (57.8% identity in 256 FT aa overlap) and SCH5.21 (EMBL:AL035636) S.coelicolor FT hypothetical protein (268 aa) (36.3% identity in 267 aa FT overlap). Contains possible hydrophobic membrane spanning FT region at C-terminal domain" FT /db_xref="GOA:Q9WX12" FT /db_xref="InterPro:IPR006385" FT /db_xref="UniProtKB/TrEMBL:Q9WX12" FT /protein_id="CAB45356.1" FT /translation="MLAGEASAEAARKSAEAAETAGTSQETTPGSGVAEPEFPVHGDDR FT AAAFFDLDNTVMQGAAIFHFGRGLYKRKFFETRDLARFAWQQAWFRLAGFEDPEHMQDA FT RDSALSIVKGHRVSELKSIGEEIYDEYMAERIWPGTRALAQAHLDAGQKVWLVTAAPVE FT IAQVIARRLGLTGALGTVAESIGGVYTGKLVGEPLHGPAKAEAVRALATAEALDLSRCA FT AYGDSHNDIPMLSLVGHPYAINPDSKLRKHARELEWRLRDYRTGRKAAKVGIPAAAGVG FT AVAGGTAAAIALHRRRR" FT CDS 50492..51025 FT /transl_table=11 FT /gene="SCO3323" FT /gene_synonym="SCE68.21" FT /product="putative RNA polymerase sigma factor" FT /note="SCE68.21, probable RNA polymerase sigma factor, len: FT 177 aa; similar to many members of the extracytoplasmic FT function sigma factor family e.g. SW:CARQ_MYXXA FT (EMBL:X71062), CarQ, Myxococcus xanthus RNA polymerase FT sigma factor (174 aa), fasta scores; opt: 237 z-score: FT 281.3 E(): 2.4e-08, 32.0% identity in 169 aa overlap. FT Similar to others from S. coelicolor e.g. TR:O54163 FT (EMBL:AL021411), SC7H1.04, possible sigma factor (200 aa) FT (30.8% identity in 172 aa overlap). Contains Pfam match to FT entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily)" FT /db_xref="GOA:Q9WX11" FT /db_xref="HSSP:1OR7" FT /db_xref="InterPro:IPR007627" FT /db_xref="UniProtKB/TrEMBL:Q9WX11" FT /protein_id="CAB45357.1" FT /translation="MELVERAQAGEADAFGRLYDQYSDTVYRYIYYRVGGKATAEDLTS FT ETFLRALRRIGTFTYQGRDFGAWLVTIARNLVADHFKSSRFRLEVTTGEMLDANEVERS FT PEDSVLESLSNAALLDAVRRLNPQQQECVTLRFLQGLSVAETARVMGKNEGAIKTLQYR FT AVRTLARLLPDDAR" FT misc_feature 50573..50779 FT /note="Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 FT factor (ECF subfamily), score 52.70, E-value 8.2e-12" FT RBS 51258..51261 FT /note="possible RBS" FT CDS 51264..52523 FT /transl_table=11 FT /gene="SCO3324" FT /gene_synonym="SCE68.22" FT /product="hypothetical protein" FT /note="SCE68.22, hypothetical protein, len: 419 aa; unknown FT function, probable serine-rich CDS suggested by positional FT base preference, GC frame analysis and amino acid FT composition. An alternative start codon is present at codon FT 4" FT /db_xref="UniProtKB/TrEMBL:Q9WX10" FT /protein_id="CAB45358.1" FT /translation="MPPVIANVSAHRRANAFAQALEEQSDPGAAAEQSGGPATAGATAE FT PTEQGRLVTLAHGLETLPRPELDPEVKVVQRAQLVAAFEAMLQEGTASGGATDTSVPEQ FT RRARGTHRAAPLSRFRPRSRLANCLTAGGLSVSVAAGAFGGVAAASSDALPGDSLYGLK FT RGIEDFRLGLADGNDERGRAYLDLASTRLSEARRLMERGRSGPLDHESLGEVRRALSGM FT RHDASEGHRLLSAAYAHDPGSLAPMQALSAFSQSHRETWGALRERLPVQLGDVSEQVSS FT VFDAIDDDVAPLQSMLPQPPAQDEGGGDAGLPGGSGSTTTGTPGSGHSSAPRTGDEGTS FT ERGRSQSDRPSESADSGDESDGLLGGGTGGLLDPPKDDSGTASPSTGGGNTPPTQPDVT FT LPPLLPGLLPGLGIEAEDAD" FT CDS complement(52565..53632) FT /transl_table=11 FT /gene="SCO3325" FT /gene_synonym="SCE68.23c" FT /product="conserved hypothetical protein" FT /note="SCE68.23c, conserved hypothetical protein, len: 355 FT aa; similar to hypothetical proteins from Mycobacterium FT tuberculosis and Mycobacterium leprae e.g. SW:YV29_MYCTU FT (EMBL:Z77162) Mycobacterium tuberculosis hypothetical FT protein (358 aa), fasta scores; opt: 1281 z-score: 1288.1 FT E(): 0, 56.5% identity in 356 aa overlap. Similar to FT TR:O54097 (EMBL:AL021529), SC10A5.04, S.coelicolor FT hypothetical protein (295 aa) (64.4% identity in 278 aa FT overlap)" FT /db_xref="GOA:Q9WX09" FT /db_xref="InterPro:IPR016676" FT /db_xref="UniProtKB/TrEMBL:Q9WX09" FT /protein_id="CAB45359.1" FT /translation="MADAKVIPFDDDRSRGSRGAGSRRRGGPAESAPAGEGPVGDVQPL FT PVRGAAAQDPAPGPDESPEPRSAVGDGGDRDEGLERRLAAGLSFLRRRLTGDYEVDDFG FT YDAELTDQVLMSLLRPVYEKYFRVEVKGVENIPAEGGALIVANHSGTLPLDGLMMQVAV FT HDHHPADRHLRLLAADLVFVLPVVNELARKLGHTLACAEDAERLLAQGELVGVMPEGFK FT GIGKPFGERYKLQRFGRGGFVSTALRQGAPIVPCSIVGAEEIYPMIGNSKTLARLLGFP FT YFPLTPTFPWLGPLGAVPLPTKWTIQFGEPIPTDGYAPEAAEDPVLMFNLTDQVREQIQ FT HTLYKLLVQRRSVFF" FT RBS complement(53644..53648) FT /note="possible RBS" FT CDS complement(53647..54708) FT /transl_table=11 FT /gene="SCO3326" FT /gene_synonym="SCE68.24c" FT /product="putative epimerase" FT /note="SCE68.24c, possible epimerase, len: 353 aa; similar FT to many e.g. SW:GALE_SALT (EMBL:M33681), galE, Salmonella FT typhimurium UDP-glucose 4-epimerase (337 aa), fasta scores; FT opt: 209 z-score: 250.6 E(): 1.2e-06, 32.1% identity in 193 FT aa overlap. Similar to hypothetical proteins from FT Mycobacterium tuberculosis and Mycobacterium leprae e.g. FT SW:YV28_MYCTU (EMBL:Z77162) Mycobacterium tuberculosis FT putative UDP-glucose 4-epimerase (376 aa) (45.0% identity FT in 353 aa overlap). N-terminal half weakly similar to the FT corresponding region of TR:O54156 (EMBL:AL021409), FT SC3F7.13, S.coelicolor probable oxidoreductase (347 aa) FT (29.8% identity in 181 aa overlap)" FT /db_xref="GOA:Q9WX08" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9WX08" FT /protein_id="CAB45360.1" FT /translation="MGKVVLVTGVARQLGGRFVRRVQRDPGVERVIGVDAVAPEHHLGG FT AEFVQADIRQSAIGRVLAQTRADTVVHLDVTGTPLGSGSRASVKETNVIGTMQLLGACQ FT KSPTVRRLVVKSSTNVYGSAPRDPAVCVETTAPKSLPSGGFAKDAVEVEGYVRGFARRR FT PDVSVTVLRFANILGPAADTPLASYFGLPVLPTVFGYDPRLQFVHEDDVIEVLRVCADE FT PRRGTLNSGTFNIAGDGVLLLSQCSRRLGRPTVPLLLPAVTWAGSLVRTLGMTDFSPEQ FT IRLLTHGRVVDTTQMRETLGFRPKYSTAGAFADFAHGRGAGLLPPEALAGAVDRIAELS FT LRGSGHLPTQSAN" FT CDS complement(54898..54996) FT /transl_table=11 FT /gene="SCO3327" FT /gene_synonym="SCE68.25c" FT /product="hypothetical protein" FT /note="SCE68.25c, hypothetical protein, len: 32 aa; unknown FT function, possible small, lysine-rich protein suggested by FT GC frameplot" FT /db_xref="InterPro:IPR013177" FT /db_xref="UniProtKB/TrEMBL:Q9WX07" FT /protein_id="CAB45361.1" FT /translation="MGSVIKKRRKRMAKKKHRKLLKRTRVQRRNKK" FT RBS complement(55003..55006) FT /note="possible RBS" FT CDS complement(55106..55318) FT /transl_table=11 FT /gene="SCO3328" FT /gene_synonym="SCE68.26c" FT /product="hypothetical protein" FT /note="SCE68.26c, hypothetical protein, len: 70 aa; similar FT to TR:Q49828 (EMBL:U00018) Mycobacterium leprae FT hypothetical protein (86 aa), fasta scores; opt: 269 FT z-score: 380.5 E(): 7.2e-14, 68.3% identity in 63 aa FT overlap. Weakly similar to putative excisionases e.g. FT TR:Q54076 (EMBL:L11597), xis, Saccharopolyspora erythraea FT excisionase (76 aa) (34.0% identity in 47 aa overlap) and FT SCE29.20c (EMBL:AL035707) S.coelicolor probable excisionase FT (66 aa) (33.3% identity in 48 aa overlap). Contains FT probable helix-turn-helix motif at aa 16-37 (Score 1251, FT +3.45 SD)" FT /db_xref="GOA:Q9WX06" FT /db_xref="InterPro:IPR010093" FT /db_xref="UniProtKB/TrEMBL:Q9WX06" FT /protein_id="CAB45362.1" FT /translation="MAAAGERPLNEVQFLTVAEVASVMRVSKMTVYRLVHSGHLPAIRV FT GRSFRVPEQAVHEYLRESYVGVETA" FT CDS complement(55448..56263) FT /transl_table=11 FT /gene="SCO3329" FT /gene_synonym="SCE68.27c" FT /product="hypothetical protein" FT /note="SCE68.27c, hypothetical protein, len: 271 aa; FT unknown function, probable CDS suggested by positional base FT preference, GC frame analysis, amino acid composition and FT possible RBS. The start codon is uncertain, alternatives FT being present at codons 19, 20 and 26" FT /db_xref="UniProtKB/TrEMBL:Q9WX05" FT /protein_id="CAB45363.1" FT /translation="MLTRGALRAHLLDVRLAGVVATSREVSLRSYRLFAARDPRVLIGI FT DPERDWGPRELLGLMAERCGVSADPRDVSGQDVIDPDRTLAALDAFAGRLAAAAGRRAP FT VLLGTGHPHRLLGFYVALAEALSAAGCTVLTPAQGRSVDITTRFGLRTYTIDYVRGVAL FT VREHGAGRAGGEPGAHTHSPLPVRTALAAAAEGGGPLPELVIGDHGWVCGAGQLGFEAI FT GPADTDDPALFVGEAEGSVSVAVPLDDAVRSEYYRPLTRYVLNRACLSR" FT RBS complement(56265..56269) FT /note="possible RBS" FT CDS complement(56557..57660) FT /transl_table=11 FT /gene="SCO3330" FT /gene_synonym="SCE68.28c" FT /product="putative acetoin utilization protein" FT /note="SCE68.28c, probable acetoin utilization protein, FT len: 367 aa; similar to proteins known to be required for FT growth on acetoin and 2,3-butanediol in Bacillus subtilis FT and Staphylococcus xylosus e.g. SW:ACUC_BACSU FT (EMBL:L17309), AcuC, Bacillus subtilis acetoin utilization FT protein (387 aa), fasta scores; opt: 910 z-score: 1032.3 FT E(): 0, 43.5% identity in 315 aa overlap. Similar to many FT histone deacetylases e.g. SW:RPD3_YEAST (EMBL:S66438), FT Rpd3, Saccharomyces cerevisiae histone deacetylases (433 FT aa) (32.0% identity in 338 aa overlap). Contains Pfam match FT to entry PF00850 Hist_deacetyl, Histone deacetylase family" FT /db_xref="GOA:Q9WX04" FT /db_xref="HSSP:1C3R" FT /db_xref="InterPro:IPR003084" FT /db_xref="UniProtKB/TrEMBL:Q9WX04" FT /protein_id="CAB45364.1" FT /translation="MDPVRLALTRSLVGALGLDREVEVVAARPAGESTLRLVHREDYID FT AVRAASADPRSADGSYGLGTVDDPAFAGMHEVSALIAGQSVGAAEAVWRGDALHAVNFA FT GGLHHAMPGAASGFCVYNDAALAIARLLELGAERVAYVDVDVHHGDGVQAAFWEDPRVL FT TVSLHEHPATLFPQTGWPEETGADCAEGSAVNVALPAGTGDAGWLRAFHAVVPEVLADF FT RPQVLVTQHGADTHFEDPLAHLAVSLDAQRAVQVACHELAHEYAGGRWVALGGGGYAVV FT EVVPRSWAHLVGVAAGRPVEPETVIPEGWRQEVYARTRQLGPMRMTDGRWPVSYASWEA FT GYDPADRLDQAVRAARRAVFPLRGLLA" FT misc_feature complement(56770..57660) FT /note="Pfam match to entry PF00850 Hist_deacetyl, Histone FT deacetylase family, score 305.80, E-value 5.2e-88" FT CDS complement(57680..58927) FT /transl_table=11 FT /gene="SCO3331" FT /gene_synonym="SCE68.29c" FT /product="putative transmembrane transport protein" FT /note="SCE68.29c, possible transmembrane transport protein, FT len: 415 aa; similar to many e.g. TR:O30996 FT (EMBL:AF024666), cmx, Corynebacterium striatum R-plasmid FT pTP10 transposon Tn5564 chloramphenicol export protein (391 FT aa), fasta scores; opt: 215 z-score: 235.6 E(): 8.4e-06, FT 24.4% identity in 390 aa overlap. Similar to TR:O69867 FT (EMBL:AL023702), SC1C3.25, S.coelicolor putative FT transmembrane transport protein (410 aa) (32.1% identity in FT 383 aa overlap). Contains hydrophobic, possible FT membrane-spanning regions" FT /db_xref="GOA:Q9WX03" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9WX03" FT /protein_id="CAB45365.1" FT /translation="MTDVLRRGRASLAFGFFAQGVAFALLVTRIPAIQDRYGVSDALLP FT VFLAAVPILAGVGSVVSERLVRRVRPSRLLRWSQPVVLLALLGVGAGDRVAVLAVALAV FT FGLAVGALDASMNMLGVSLQRAYGRSIMLGFHAAYSLGGILGASLAWAGAHWDLALWVS FT YLPVVVLLLPAALVGSRWYVDGGREGAEGAGAGEGTGGVGAGVGFKVLLPLCLVMTFAY FT IGDSTVSNWSAKYLQDVLGSSEQLATVPYNVYMVTTLVGRALGDFGVRRFGAVAVVRGG FT AVVAAGGFAVVASAPGAWVGMLGFTLLGLGLCVLVPQTFAAAGRLAAEKDGRPGASDAA FT VARLNVFNYVGFLIGSPLVGALGDAWSYRGAMLVPMVLVLVTVVYARSFEGQPDRYGGG FT HERPRTADVGRGSNGL" FT CDS complement(58951..59667) FT /transl_table=11 FT /gene="SCO3332" FT /gene_synonym="SCE68.30c" FT /product="putative membrane protein" FT /note="SCE68.30c, possible membrane protein, len: 238 aa; FT unknown function, probable CDS suggested by positional base FT preference, GC frame analysis and amino acid composition. FT Contains hydrophobic, possible membrane-spanning regions. FT Alternative start codons are present at codons 10 and 11." FT /db_xref="UniProtKB/TrEMBL:Q9WX02" FT /protein_id="CAB45366.1" FT /translation="MTKPRKSRTVVSLLLDVGVPVGSYYLLKGAFGMSAVAALGWSSAG FT PVLRTGWGVLRQREVNVLPLLILLANLAGLLIGFGTGDARLMLAKDSAVTSLVGFALLG FT SVALGRPMMTATLKPWLVKGDAGREAAWGRLRRESPAFRRAELRFSAVWGVAFVGECGV FT RIVRVYALPVDTMVWLGTVVMIVTMLVAFVVSGALGAGPMVHMIGAAVTTDDSADAFDA FT VLEAEKNSSLVGSTHG" FT CDS complement(59744..60391) FT /transl_table=11 FT /gene="SCO3333" FT /gene_synonym="SCE68.31c" FT /product="putative hydrolase" FT /note="SCE68.31c, possible hydrolase, len: 215 aa; similar FT to many e.g. TR:O68118 (EMBL:AF010496) Rhodobacter FT capsulatus hypothetical protein (225 aa), fasta scores; FT opt: 456 z-score: 540.0 E(): 9.4e-23, 38.5% identity in 221 FT aa overlap. Weakly similar to SW:GPH_RHOCA (EMBL:U23145), FT cbbZ, Rhodobacter capsulatus phosphoglycolate phosphatase FT (219 aa) (24.0% identity in 217 aa overlap). Contains Pfam FT match to entry PF00702 Hydrolase, haloacid FT dehalogenase-like hydrolase" FT /db_xref="GOA:Q9WX01" FT /db_xref="InterPro:IPR006402" FT /db_xref="UniProtKB/TrEMBL:Q9WX01" FT /protein_id="CAB45367.1" FT /translation="MRYDLVIFDNDGVLVDSEPISNRLLAGYLTELGHPTSYEDSLRDY FT MGGAMHRVHDLVLERTGRRLPSDFDDVFHGRVFAAFERELEPVPGAVDVLEKLAADGVA FT YCVASSGSHERIRTGHRTAGLDRWFDDERIFSSQDVGRGKPAPDLFLHAAARMGVAPER FT CVVVEDSPLGVRAAVAAGMDVYGFTAMTPAEKLDGATRLFGDMGELADLLRG" FT misc_feature complement(59822..60385) FT /note="Pfam match to entry PF00702 Hydrolase, haloacid FT dehalogenase-like hydrolase, score 112.90, E-value 6.1e-30" FT stem_loop complement(60414..60439) FT /note="stem is 11 bp perfect match; loop is 4 bp" FT rRNA complement(60454..60572) FT /gene="rrnF" FT /note="probable 5S rRNA, coordinates taken from similarity FT to Streptomyces rimosus 5S rRNA gene of the rrnF gene set FT (EMBL:X62884)" FT rRNA complement(60656..63779) FT /gene="rrnF" FT /note="probable 23S rRNA, coordinates taken from similarity FT to Streptomyces rimosus 23S rRNA gene of the rrnF gene set FT (EMBL:X62884)" FT rRNA complement(64060..65587) FT /gene="rrnF" FT /note="probable 16S rRNA, coordinates taken from similarity FT to Streptomyces coelicolor 16S rRNA gene of the rrnD gene FT set (EMBL:Y00411)" FT CDS 66424..67434 FT /transl_table=11 FT /gene="SCO3334" FT /gene_synonym="SCE68.32" FT /gene_synonym="trpS" FT /gene_synonym="SCE7.01" FT /product="tryptophanyl tRNA synthetase" FT /note="SCE68.32, trpS, probable tryptophanyl-tRNA FT synthetase, partial CDS, len: >160 aa; similar to many e.g. FT SW:SYW_ECOLI (EMBL:V00371), trpS, Escherichia coli FT tryptophanyl-tRNA synthetase (334 aa), fasta scores; opt: FT 530 z-score: 670.6 E(): 5e-30, 50.0% identity in 162 aa FT overlap. Contains PS00178 Aminoacyl-transfer RNA FT synthetases class-I signature" FT /note="SCE7.01, trpS, tryptophanyl tRNA synthetase, len: FT >208aa; similar to many eg. SW:SYW_BACST trpS, tryptophanyl FT tRNA synthetase from Bacillus stearothermophilus (328 aa) FT fasta scores; opt: 576, z-score: 685.7, E(): 7.2e-31, FT (47.8% identity in 203 aa overlap)." FT /db_xref="GOA:Q8CJX0" FT /db_xref="HSSP:1I6M" FT /db_xref="InterPro:IPR002306" FT /db_xref="UniProtKB/Swiss-Prot:Q8CJX0" FT /protein_id="CAD55313.1" FT /translation="MTRVFSGVKPTGHLTLGNYLGAMRRWAAVDQHRSDALFCVVDLHA FT LTVDHDPARVRRLSRQAASLLLAAGLDPELCTVFVQSHVDEHARLSYVLECVATDGEMR FT RMIQYKEKAARERVRGGSVRLSLLTYPVLMAADILAYGTDEVPVGEDQTQHVELARDLA FT VRFNQRYGHTFVVPRATSPAVAARVMNLQEPASKMGKSDDTGPGIVYLLDEPDVVRKKV FT MRAVTDSGRDVVYDPEERAGLANLLEILAACTDGEPAELAGGYDSYGALKKDTAEAVVE FT MLRPVRERHMELSADPGYVDGVLREGAEKARAMARPTVDDAYRAIGLLPPVNAAR" FT misc_feature 66451..66480 FT /note="PS00178 Aminoacyl-transfer RNA synthetases class-I FT signature" FT CDS complement(67389..68393) FT /transl_table=11 FT /gene="SCO3335" FT /gene_synonym="SCE7.02c" FT /product="putative araC-family transcriptional regulator" FT /note="SCE7.02c, probable AraC-family transcriptional FT regulator, len: 334 aa; similar to many e.g. TR:CAB40696 FT (EMBL:AL049587) putative transcriptional regulator (325 aa) FT fasta scores; opt: 643, z-score: 750.6, E(): 0, (39.9% FT identity in 316 aa overlap) and TR:O30507 (EMBL:AF008308) FT from Pseudomonas aeruginosa (328 aa) fasta scores; opt: FT 360, z-score: 423.1, E(): 3e-16, (27.7% identity in 328 aa FT overlap). Contains Pfam match to entry PF00165 HTH_2, FT Bacterial regulatory helix-turn-helix proteins, araC FT family. Also contains probable helix-turn-helix motif FT (+4.06 SD) at 241-262aa." FT /db_xref="GOA:Q9X8F9" FT /db_xref="InterPro:IPR002818" FT /db_xref="UniProtKB/TrEMBL:Q9X8F9" FT /protein_id="CAB42661.1" FT /translation="MAGAAASAAAPYRVALVAFPGIRAFDVAVITEVWGTDRTDRGAPA FT FDLRRVAADGTTAVPMRGGLALHPDRPLDWLAEADLVVVPGLDDHLTPAPAPVLAALRR FT AHDRGTTVAALCGGAFTLAQAGLLDGRRAITHWRLLDLLRTRHPRVTVVPDALFIEDDN FT IWTAAGTAAGIDLCLHLVRLAHGAEAAATIARSMVTAPFRTGTQAQFIEHPTHHADRDA FT DALAGVREHALRHLDEPLTVADLAARAGMSPRSFARHFAAATGTTPLRWLLDQRIAAAQ FT KLLERTDLPMPEVARRAGFGSEVMMRQHFAARLATSPRAYRAAFTGGSSPIAR" FT misc_feature complement(67419..67679) FT /note="Pfam match to entry PF00165 HTH_2, Bacterial FT regulatory helix-turn-helix proteins, araC family, score FT 76.20, E-value 6.7e-19." FT CDS 68468..69049 FT /transl_table=11 FT /gene="SCO3336" FT /gene_synonym="SCE7.03" FT /product="putative hydrolase" FT /note="SCE7.03, possible hydrolase, len: 193aa; similar to FT many egs. TR:O07081 (EMBL:U93876) hypothetical protein from FT Bacillus subtilis (187 aa) fasta scores; opt: 370, z-score: FT 455.2, E(): 5e-18, (35.1% identity in 188 aa overlap) and FT SW:ENTB_ECOLI isochorismatase from Escherichia coli (285 FT aa) fasta scores; opt: 133, z-score: 168.5, E(): 0.046, FT (29.1% identity in 196 aa overlap). Contains Pfam match to FT entry PF00857 Isochorismatase, Isochorismatase family." FT /db_xref="GOA:Q9X8G0" FT /db_xref="HSSP:1J2R" FT /db_xref="InterPro:IPR000868" FT /db_xref="UniProtKB/TrEMBL:Q9X8G0" FT /protein_id="CAB42662.1" FT /translation="MDIAENAALVVVDVQKGFEEVDFWGTRNNPAADDNIAALIDAWQS FT AGRPVVFVRHDSVQAGSPLREGYEGNGFKEYVEQRRGKGGGAELLVTKSVNSAFLGAPD FT LGAWLRAAGIRQLVLAGIQTNMCVETTARMGGNLGYEVVVPLDATYTFGLEGPFGWRQS FT ADELARASAVSLHGGGFARVVTTEEVLAGS" FT misc_feature 68489..68959 FT /note="Pfam match to entry PF00857 Isochorismatase, FT Isochorismatase family, score 50.00, E-value 5.2e-11." FT CDS complement(69113..69967) FT /transl_table=11 FT /gene="SCO3337" FT /gene_synonym="SCE7.04c" FT /gene_synonym="proC" FT /product="pyrroline-5-carboxylate reductase" FT /note="SCE7.04c, proC, pyrroline-5-carboxylate reductase, FT len: 284aa; highly similar to many from prokaryotes and FT eukaryotes egs. SW:PROC_CORGL proC, pyrroline-5-carboxylate FT reductase from Corynebacterium glutamicum (270 aa) fasta FT scores; opt: 735, z-score: 832.5, E(): 0, (46.2% identity FT in 264 aa overlap) and SW:PROC_ARATH proC, FT pyrroline-5-carboxylate reductase from Arabidopsis thaliana FT (276 aa) fasta scores; opt: 604, z-score: 685.7, E(): FT 7.1e-31, (41.1% identity in 265 aa overlap). Contains Pfam FT match to entry PF01089 P5CR, Delta FT 1-pyrroline-5-carboxylate reductase and Prosite match to FT PS00521 Delta 1-pyrroline-5-carboxylate reductase FT signature." FT /db_xref="GOA:Q9X8G1" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9X8G1" FT /protein_id="CAB42663.1" FT /translation="MTPDHAHTPEGTEPMTQKVAVLGTGKIGEALLSGMIGAGWAPADL FT LVTARRRERADELRARHGVTPVTNAEAAKAADTLILTVKPQDMGTLLDELAPHVPADRL FT VISGAAGVPTSFFEERLAPGTPVVRVMTNTPALVDEAMSVISAGTHATAAHLTHTEEIF FT GAVGKTLRVPESQQDACTALSGSGPAYFFYLVEAMTDAGILLGLPRDKAHDLIVQSAIG FT AAKMLRDSGEHPVKLRENVTSPAGTTINAIRELENHGVRAALIAALEAARDRSRELATG FT TKD" FT misc_feature complement(69179..69919) FT /note="Pfam match to entry PF01089 P5CR, Delta FT 1-pyrroline-5-carboxylate reductase, score 327.60, E-value FT 1.4e-94." FT misc_feature complement(69200..69268) FT /note="PS00521 Delta 1-pyrroline-5-carboxylate reductase FT signature." FT CDS complement(70173..70973) FT /transl_table=11 FT /gene="SCO3338" FT /gene_synonym="SCE7.05c" FT /product="putative integral membrane protein" FT /note="SCE7.05c, probable integral membrane protein, len: FT 266aa; similar to many hypothetical proteins eg. TR:O33188 FT (EMBL:Z98268) from Mycobacterium tuberculosis (226 aa) FT fasta scores; opt: 661, z-score: 725.6, E(): 4.3e-33, FT (45.1% identity in 226 aa overlap). Contains possible FT membrane spanning hydrophobic regions." FT /db_xref="GOA:Q9X8G2" FT /db_xref="InterPro:IPR013525" FT /db_xref="UniProtKB/TrEMBL:Q9X8G2" FT /protein_id="CAB42664.1" FT /translation="MTTPTAPAPPAPALTPAPTRPLSLARTTATATRVLRQLSHDPRTI FT ALLMLIPCVMLFLLRYVFDGSPRTFDNIGASLLGIFPLITMFLVTSIATLRERTSGTLE FT RLLAMPLGKGDLIAGYALAFGALAIVQSALATGLAVWFLGLDVTGSPWLLLLVALLDAL FT LGTALGLFVSAFAASEFQAVQFMPAVIFPQLLLCGLFTPRDNMHPALEAVSDVLPMSYA FT VDGMNEVLRHTDMTATFVRDALIVAGCALLVLALGAATLKRRTA" FT CDS complement(70970..71800) FT /transl_table=11 FT /gene="SCO3339" FT /gene_synonym="SCE7.06c" FT /product="putative ABC transporter ATP-binding subunit" FT /note="SCE7.06c, probable ABC transporter ATP-binding FT subunit, len: 276aa; similar to many eg. TR:O33189 FT (EMBL:Z98268) ABC-type transport protein from Mycobacterium FT tuberculosis (255 aa) fasta scores; opt: 811, z-score: FT 850.0, E(): 0, (53.8% identity in 251 aa overlap) and FT TR:Q53626 (EMBL:U43537) ABC protein in mithramycin FT resistance (320 aa) fasta scores; opt: 491, z-score: 517.8, FT E(): 1.6e-21, (37.0% identity in 230 aa overlap). Contains FT Pfam match to entry PF00005 ABC_tran, ABC transporter and FT Prosite matches to PS00211 ABC transporters family FT signature and PS00017 ATP/GTP-binding site motif A FT (P-loop)." FT /db_xref="GOA:Q9X8G3" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9X8G3" FT /protein_id="CAB42665.1" FT /translation="MMNYPTEHSSPPPEGQGGDPAPPAVHAEDLTVVRGPRTVLRVLGF FT TVPRGRITGLLGPSGCGKSTLMRAIVGTQAKVTGTLDVLGRPAGHPALRTRIGYVTQAP FT SVFDDLTVRQNLDYFAEILDPGRAASDRRRDDVTRVIADVDLTAHADALAGNLSGGQRS FT RVSLAVALLGAPELLVLDEPTVGLDPVLRRDLWTLFHSIAADRGATLLVSSHVMDEAER FT CHRLLLMREGEVLADDTPDALRTRTGSETVEEAFLHLVDEAKDKAAARTKETTR" FT misc_feature complement(71105..71653) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 187.00, E-value 2.9e-52." FT misc_feature complement(71288..71332) FT /note="PS00211 ABC transporters family signature." FT misc_feature complement(71609..71632) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS complement(71941..72723) FT /transl_table=11 FT /gene="SCO3340" FT /gene_synonym="SCE7.07c" FT /product="hypothetical protein" FT /note="SCE7.07c, unknown, len: 400 aa; similar to TR:O53392 FT (EMBL:AL021841) hypothetical protein from Mycobacterium FT tuberculosis (243 aa) fasta scores; opt: 424, z-score: FT 497.4, E(): 2.2e-20, (35.8% identity in 226 aa overlap)." FT /db_xref="GOA:Q9X8G4" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:Q9X8G4" FT /protein_id="CAB42666.1" FT /translation="MTTPPQADHSARAHSFNAAAAQYAANRPSYPPALFDALEELTGRP FT LKGSRVVDVGAGTGLATARLHERGADVIAVEPGAGMAAEFRRTLPGVPVVRGNGNALPL FT ADHGADLLTYAQSWHWTDPTLAVPEALRVLRPGGALALWWNTDAHDVPWIADSGRRIDR FT HFAGLNLSAEKRNFDARFADPTGNLDFVHHEIRWSRRVPLDTHLANLGSHSVFLTDTEE FT RATAFFAEERRHLLAVFPDGLVEETYDVHLLLAPTSTT" FT repeat_region 72806..73806 FT /note="Complex repeat region." FT stem_loop 72953..73207 FT /note="Score 55: 45/62 ( 72%) matches, 1 gaps 6147-6401." FT stem_loop 73135..73489 FT /note="Score 70: 54/71 ( 76%) matches, 2 gaps 6329-6683." FT stem_loop 73385..73669 FT /note="Score 57: 43/61 ( 70%) matches, 0 gaps 6579-6863." FT CDS complement(73720..74223) FT /transl_table=11 FT /gene="SCO3341" FT /gene_synonym="SCE7.08c" FT /product="putative integral membrane protein" FT /note="SCE7.08c, possible integral membrane protein, len: FT 167aa; Contains possible membrane spanning hydrophobic FT regions." FT /db_xref="UniProtKB/TrEMBL:Q9X8G5" FT /protein_id="CAB42667.1" FT /translation="MSAENGKNGIPDTQAGPRPEPLRFYGTTWVNHDDGYAARRAGLAV FT GSLAVAAAACFVLRVAYQGLQIADIGSFVSLLMIVMFAICSALAFRHTWSGFTSRPDPD FT RQASMRGLLAIGFVGSLLAYFFRTFTEAPGEKLHRAEYDRAREDYEKRTTRRSGNPMKK FT RRRK" FT CDS complement(74265..74939) FT /transl_table=11 FT /gene="SCO3342" FT /gene_synonym="SCE7.09c" FT /product="putative glycine-rich secreted protein" FT /note="SCE7.09c, possible glycine-rich secreted protein, FT len: 224aa; Contains a possible N-terminal signal sequence. FT Also contains Prosite match to PS00013 Prokaryotic membrane FT lipoprotein lipid attachment site." FT /db_xref="UniProtKB/TrEMBL:Q9X8G6" FT /protein_id="CAB42668.1" FT /translation="MRVRKLTIAAMALAAGLSLTACQNDDDAAGQSTAPPAASTAASSD FT GGSGSAGSDSAESSNGTGGTGGTEGTEGSGGTGGAGEDGKAAKCSTDELEITAADATVG FT GDTEGTVAVDLKNGGGRDCSLAGYAGVDLKTNSGTVSAERTGDPAPRVVLKDGETVTFG FT ITYPVNDSGGSGVRITGLVVTPPDETKSVTLDWPGGASLPVTDGSGTPVRVGPLGSAGQ FT GG" FT misc_feature complement(74874..74906) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site." FT CDS complement(75106..75480) FT /transl_table=11 FT /gene="SCO3343" FT /gene_synonym="SCE7.10c" FT /product="hypothetical protein" FT /note="SCE7.10c, unknown, len: 124 aa; similar to FT SW:YRAI_BACSU hypothetical protein from Bacillus subtilis FT (144 aa) fasta scores; opt: 252, z-score: 308.2, E(): FT 7.6e-10, (42.4% identity in 92 aa overlap)." FT /db_xref="InterPro:IPR013247" FT /db_xref="UniProtKB/TrEMBL:Q9X8G7" FT /protein_id="CAB42669.1" FT /translation="MPRESRGVFNGGSFFMSVDQVQNIGGGEEGEKTGGEGVVAAAALR FT SYPVAPGYRLNVRSGPGTNYSTVRVLAEGSRVTINCQRTGQWVSGPYGTSNIWDNIGGG FT QYVSDAYILTGSDGWVAPRC" FT CDS 75621..77783 FT /transl_table=11 FT /gene="SCO3344" FT /gene_synonym="SCE7.11" FT /product="putative serine/threonine protein kinase" FT /note="SCE7.11, probable serine/threonine protein kinase, FT len: 720 aa; similar to many from other Streptomyces spp. FT eg. SW:AFSK_STRCO serine/threonine protein kinase from FT Streptomyces coelicolor (799 aa) fasta scores; opt: 896, FT z-score: 827.4, E(): 0, (33.1% identity in 771 aa overlap). FT Contains Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain and Prosite matches to PS00107 FT Protein kinases ATP-binding region signature and PS00108 FT Serine/Threonine protein kinases active-site signature. FT Also contains five Pfam matches to entry PF01011 FT Bacterial_PQQ, PQQ enzyme repeat." FT /db_xref="GOA:Q9X8G8" FT /db_xref="HSSP:1MRU" FT /db_xref="InterPro:IPR011047" FT /db_xref="UniProtKB/TrEMBL:Q9X8G8" FT /protein_id="CAB42670.1" FT /translation="MAPQRDAGADAEAELPEYAGHYRLESRLGSGGMGVVHLARSTSGM FT RVAVKVVHATYARDPEFRGRFRQEVAAARRVSGAFTAPVVDADPEAGRPWMATLFIPGP FT TLSEQVKRNGPMDEPQLRRLMAGLAEALRDIHRVGVVHRDLKPSNVLLAEDGPKVIDFG FT ISRPKDSELRTETGKLIGTPPYMAPEQFRRPREVGPAADVFTLGSLMVHAATGRGPFDS FT DSPYVVAYQVVHDEPDLTGVPDSLAPLVLRCLAKEPEDRPTPDELMRELRSVAAAYDTQ FT VFIPAPRTERAETPAEAGAEPAPRASVEPSGPSEPSEPSERSGRVLRRLGKRSALVAGA FT VGLAVVGSLVAVQAFGGSEPAGTPTAQSAPGGFGAWEAVPAAQGGGMPQCSYAARRLLC FT ARPGVVFALDPADGSTLWRHPVEETVRSEPPVVSGGLVQPEVGLLGPLEALDPATGEPE FT WQEDMPAYDGLRTVGDMLLLTRADGMVTGVDSSSGRTRWAHRIPGQAVPYFTSFAGERH FT PAAYATSQSADGRRTHVTAVDPAGGDVRWDTELAGALTPVGTADGSVFLVVEGATYGDV FT TAVVRYTPATGATRRVTLPIPVEQASASAGVRGDTVYLMGAGGSLVAVDMAAEKQAWRL FT ETGVSRGSAPVSDGRHVYVTAPDGRLLGVDARKGKLLGQTRPRLGADSDTVPASLPAPL FT LAGGHVYAGAPDGTVFGVAGRDPGGW" FT misc_feature 75684..76424 FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 136.30, E-value 5.5e-37." FT misc_feature 75702..75770 FT /note="PS00107 Protein kinases ATP-binding region FT signature." FT misc_feature 76038..76076 FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature." FT misc_feature 76800..76913 FT /note="Pfam match to entry PF01011 Bacterial_PQQ, PQQ FT enzyme repeat, score 23.20, E-value 0.0061." FT misc_feature 76935..77039 FT /note="Pfam match to entry PF01011 Bacterial_PQQ, PQQ FT enzyme repeat, score 4.00, E-value 17." FT misc_feature 77040..77153 FT /note="Pfam match to entry PF01011 Bacterial_PQQ, PQQ FT enzyme repeat, score 15.00, E-value 0.4." FT misc_feature 77448..77561 FT /note="Pfam match to entry PF01011 Bacterial_PQQ, PQQ FT enzyme repeat, score 10.00, E-value 2.2." FT misc_feature 77568..77681 FT /note="Pfam match to entry PF01011 Bacterial_PQQ, PQQ FT enzyme repeat, score 15.40, E-value 0.35." FT CDS complement(77809..79662) FT /transl_table=11 FT /gene="SCO3345" FT /gene_synonym="SCE7.12c" FT /product="dihydroxy acid dehydratase" FT /note="SCE7.12c, ilvD, dihydroxy acid dehydratase, len: FT 617aa; previously sequenced therefore almost (conflict of 3 FT amino acids) identical to TR:O69198 (EMBL:AF068843) ilvD, FT dihydroxy acid dehydratase from Streptomyces coelicolor FT (617 aa) fasta scores; opt: 4019, z-score: 4363.1, E(): 0, FT (99.2% identity in 617 aa overlap). Also similar to FT SW:ILVD_ECOLI ilvD, dihydroxy acid dehydratase from FT Escherichia coli (605 aa) fasta scores; opt: 2644, z-score: FT 2871.0, E(): 0, (66.5% identity in 606 aa overlap). FT Contains Pfam match to entry PF00920 ILVD_EDD, Dehydratase FT family and Prosite matches to PS00887 Dihydroxy-acid and FT 6-phosphogluconate dehydratases signature 2 and PS00886 FT Dihydroxy-acid and 6-phosphogluconate dehydratases FT signature 1." FT /db_xref="GOA:O69198" FT /db_xref="InterPro:IPR000581" FT /db_xref="UniProtKB/Swiss-Prot:O69198" FT /protein_id="CAB42671.1" FT /translation="MPELRSRTVTHGRNMAGARALMRASGVPGADIGRKPIIAVANSFT FT EFVPGHTHLAPVGRIVSEAVTAAGGIPREFNTIAVDDGIAMGHGGMLYSLPSRDLIADS FT VEYMVEAHCADALICISNCDKITPGMLNAALRLNIPTVFVSGGPMESGRATLVDGTVRT FT LDLVDAMSEAVNDKISDADILRIEENACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGS FT VLATHTARKTLYENAARTVLDLTRRYYEQDDDSVLPRNIATPAAFGNAMALDIAMGGST FT NTILHLLAAAQEAEVSYGLAEMDALSRSVPCLAKVAPNVAKDRTYYMEDVHRAGGIPAL FT LGELHRGGLLNEDVHSVHSPSLADWLKTWDVRGGSPSKEAVELWHAAPGCVRSAEAFSQ FT SERWDTLDEDAEGGCIRSVEHAYSKDGGLAVLRGNLAVDGCVVKTAGVDESIWTFEGPA FT VVCESQEEAVQKILTQQVKEGDVVVIRYEGPKGGPGMQEMLYPTSYLKGRGLGKACALV FT TDGRFSGGTSGLSIGHASPEAAAGGTIALVEDGDRIRIDIPNRSIELLVDDAELTRREQ FT ALNGVYAPKNRDRKVSAALKAYAAMATSADKGAVRDVSKLG" FT misc_feature complement(77965..79470) FT /note="Pfam match to entry PF00920 ILVD_EDD, Dehydratase FT family, score 844.00, E-value 5.1e-250." FT misc_feature complement(78085..78120) FT /note="PS00887 Dihydroxy-acid and 6-phosphogluconate FT dehydratases signature 2." FT misc_feature complement(79264..79296) FT /note="PS00886 Dihydroxy-acid and 6-phosphogluconate FT dehydratases signature 1." FT CDS complement(79818..80432) FT /transl_table=11 FT /gene="SCO3346" FT /gene_synonym="SCE7.13c" FT /product="putative transcriptional regulator" FT /note="SCE7.13c, possible transcriptional regulator, len: FT 204 aa; similar to SW:UIDR_ECOLI uid operon repressor from FT Escherichia coli (196 aa) fasta scores; opt: 168, z-score: FT 207.0, E(): 0.00033, (28.7% identity in 188 aa overlap). FT Contains Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family. Note N-terminal region FT previously sequenced and annotated as a UDP-MurNAc FT L-alanine ligase-like protein therefore almost (conflict of FT two amino acids) identical to TR:O87451 (EMBL:AF068843) (63 FT aa) fasta scores; opt: 392, z-score: 473.9, E(): 4.5e-19, FT (96.8% identity in 63 aa overlap)." FT /db_xref="GOA:Q9X8G9" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9X8G9" FT /protein_id="CAB42672.1" FT /translation="MNGDAGGTTRRRGRPPGTESGDTRDRILTTAREEFSERGYEKTSV FT RGIAKAAGVDPALVHHYFGTKEQVFEAAIEVAFAPALRAPDAIGDAPLDEVGERLTRFI FT LGLWENPASRTPLLAIVRSAVNNETAATVFRRLIATQVLRRVAAQLHLPDAELRVELAA FT AQLVGCAMLRYVIKVEPLASADPEQIVARLAPVVQGHLTGP" FT misc_feature complement(80214..80354) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 47.80, E-value FT 1.6e-11." FT CDS complement(80429..81286) FT /transl_table=11 FT /gene="SCO3347" FT /gene_synonym="SCE7.14c" FT /product="conserved hypothetical protein" FT /note="SCE7.14c, unknown, len: 285aa; similar to FT SW:YV24_MYCTU hypothetical protein from Mycobacterium FT tuberculosis (280 aa) fasta scores; opt: 569, z-score: FT 688.7, E(): 4.9e-31, (54.6% identity in 273 aa overlap)" FT /db_xref="InterPro:IPR012307" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8H0" FT /protein_id="CAB42673.1" FT /translation="MAKPSDAVRIQDTKVALSTASVYPESTATAFEIAARLGYDGVEVM FT VWTDPVSQDIEALRRLSDYHRMPILAVHAPCLLITQRVWSTDPWVKLQRARAAAEKLGA FT STVVVHPPFRWQRQYARDFVDGIWRMADETDVRFAVENMYPWRYRDREMQAYAPDWDVT FT KDDYRHFTIDLSHAATSRTDTLDMIDRMSDRLGHVHLADGKGSAKDEHLVPGRGNQPCA FT EVLERLAHTGFDGHVVIEVNTRRAMSGAEREADLAEALAFTRLHLAQTVSPVPGGPATR FT TDRR" FT CDS complement(81448..82377) FT /transl_table=11 FT /gene="SCO3348" FT /gene_synonym="SCE7.15c" FT /product="putative DNA-binding protein" FT /note="SCE7.15c, possible DNA-binding protein, len: 309 aa; FT similar to SW:YV22_MYCTU hypothetical protein from FT Mycobacterium tuberculosis (328 aa) fasta scores; opt: 991, FT z-score: 1143.8, E(): 0, (55.0% identity in 289 aa overlap) FT and similar to N-terminal region of SW:PPX_ECOLI FT (EMBL:L06129) Escherichia coli exopolyphosphatase Ppx, 512 FT aa; fasta scores: opt: 286 Z-score: 317.1 E(): 5e-10; FT 25.329% identity in 304 aa overlap. Contains possible FT helix-turn-helix motif (+3.03 SD) at 251..272 aa" FT /db_xref="GOA:Q9X8H1" FT /db_xref="InterPro:IPR003695" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8H1" FT /protein_id="CAB42674.1" FT /translation="MRLGVLDVGSNTVHLLVVDAHPGARPLPAHSHKVELRLAQLLDED FT GAIGPDGVDQLAAVVREALQAAEDKGVEDLLPFATSAVREASNADDVLARVRAETGVEL FT TVLTGAEEARLTFLAARRWFGWSAGRLLVLDIGGGSLEIAYGMDEEPDAAVSLPLGAGR FT LTAARLPDDPPHPDDVRALRRHVRTEIARTVGEFSRLGAPDHVVATSKTFRQLARITGA FT ARSAEGLYVQRELKRASLEAWVPRLAAMTSTERAELPGVSEGRAHQLLAGALVAEGAMD FT LFRVESLEICPWALREGVILRRLDHMGQ" FT CDS 82449..83264 FT /transl_table=11 FT /gene="SCO3349" FT /gene_synonym="SCE7.16" FT /product="conserved hypothetical protein" FT /note="SCE7.16, unknown, len: 271aa; similar to FT SW:YV21_MYCTU hypothetical protein from Mycobacterium FT tuberculosis (296 aa) fasta scores; opt: 966, z-score: FT 1180.4, E(): 0, (50.4% identity in 278 aa overlap)" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8H2" FT /protein_id="CAB42675.1" FT /translation="MPKTKKAKDEKSAKKDKKHIAGDEKGLDFARAWVEFPDPADDEQV FT FRCDLTWLTSRWNCIFGSGCQGIQAGRADDGCCSLGAHFSDEDDEKRVAGHVARLTPDI FT WQHHAEGTRNGWTSEDDEGSRQTRPFQGSCIFQNRPGFAGGAGCSLHILALKEGREPLE FT TKPDVCWQLPVRRTYEWIDRPDDTRVLQVSIGEYDRRGWGPGGHDLHWWCTSATSAHGA FT GDPVYVSYRPELVELMGKAGYDRLVELCEERLASQLPLLAPHPADPAGR" FT CDS complement(83328..85124) FT /transl_table=11 FT /gene="SCO3350" FT /gene_synonym="SCE94.01c" FT /gene_synonym="SCE7.17c" FT /product="hypothetical protein" FT /note="SCE94.01c, partial CDS unknown, alanine-rich FT protein, len: >503aa;" FT /note="SCE7.17c, partial CDS, proline-rich protein, len: FT >129aa;" FT /db_xref="UniProtKB/TrEMBL:Q8CJW9" FT /protein_id="CAD55314.1" FT /translation="MRSSPETTTRTTGAHRAHREARDRTAARALAQPPAQRPPARYAAY FT DAYLDGLFTYCLSVLCDHDAATAALGDVLAIAERRGHRGPAPAADRRSWLYALARWACL FT RKLAEAKQKRPSTHAAGRPAPVTRQTAQTTPTAPTTPTNDETHQRHRSELALLAWPEAA FT GTTPEQREALELAVRHHLAPHEVAAVLGTDLAATRELLASAACEVERTRAALAVVETGT FT CAGVARLTGDNRYVLSTALRRELVRHVDDCPRCRRTAERAIPGRWPGTSVTPAELPVLE FT APRTALHVALAHTSRARSAAPRFDRRGFPMDPKDRAARRDRLRARAVTTTVVATVVAAP FT VLALWAAYRGTPVVEGEEGRSASASEAQDPDATDGESAGGAYGYENAGNASTTPGTGFG FT EKGGADVSVEVVGVSGASGKAAGHLEVTAGHDGDTTLVTLTATGDAPVHWSASVGASWL FT YLSQSSGTLRPGEAVTVRVYVDHLREPSGRWSARVAVSPAGAVVAIEGYGTAPAPSRPG FT PRPGPPDDTSSPSHPGGDPDPGPDPSPSTSQPPDPTPTGDPSPTPPDPDPTTNEPSPTG FT GTNGSSPPPGNSDSGAPSPSDS" FT CDS 85738..87147 FT /transl_table=11 FT /gene="SCO3351" FT /gene_synonym="SCE94.02" FT /product="putative DNA repair protein" FT /note="SCE94.02, possible DNA repair protein, len: 469aa; FT similar to many eg. SW:RADA_ECOLI RadA, DNA repair protein FT (mechanism unknown) from Escherichia coli (460 aa) fasta FT scores; opt: 1218, z-score: 1309.3, E(): 0, (41.4% identity FT in 452 aa overlap). Contains Prosite match to PS00017 FT ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q9X8L5" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9X8L5" FT /protein_id="CAB40851.1" FT /translation="MAARTKSAKERPSYRCTECGWQTAKWLGRCPECQAWGTVEEYGAP FT AVRTTTPGRVTTSAVPIGQVDGRQATARSTGVPELDRVLGGGLVPGAVVLVAGEPGVGK FT STLLLDVAAKSASDEHRTLYVTGEESASQVRLRADRIHAIDDHLYLAAETDLAAVLGHL FT DAVKPSLLILDSVQTVASPEIDGAPGGMAQVREVAGALIRASKERGMSTLLVGHVTKDG FT AIAGPRLLEHLVDVVLHFEGDRHARLRLVRGVKNRYGTTDEVGCFELHDEGITGLADPS FT GLFLTRRAEPVPGTCLTVTLEGRRPLVAEVQALTVDSQIPSPRRTTSGLETSRVSMMLA FT VLEQRGRISALGKRDIYSATVGGVKLSEPAADLAVALALASAASDTPLPKNLVAIGEVG FT LAGEVRRVTGVQRRLSEAHRLGFTHALVPADPGRVPDGMKVLEVADMGDALRVLPRSRR FT REATREEEDRR" FT misc_feature 86029..86052 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 87229..88353 FT /transl_table=11 FT /gene="SCO3352" FT /gene_synonym="SCE94.03" FT /product="putative DNA-binding protein" FT /note="SCE94.03, possible DNA-binding protein, len: 374 aa; FT similar to hypothetical proteins eg. TR:O53571 FT (EMBL:AL022075) from Mycobacterium tuberculosis (358 aa) FT fasta scores; opt: 1338, z-score: 1480.9, E(): 0, (59.9% FT identity in 347 aa overlap). Contains Pfam match to entry FT PF00633 HHH, Helix-hairpin-helix motif." FT /db_xref="GOA:Q9X8L6" FT /db_xref="InterPro:IPR000445" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8L6" FT /protein_id="CAB40852.1" FT /translation="MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTSLRDGLERVLR FT GNTGGLIVLGSDKTVESMCTGGFVLDVEFTATRLRELCKLDGGIVLSSDLSKILRAGVQ FT LLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAAILS FT RANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVV FT ELGTDGRLLALQLDELIAGVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLSHAELL FT ELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGAIIDRLVEHFGGLQKLLAASV FT DDLQTVDGVGEARARSVREGLSRLAESSILERYV" FT misc_feature 88219..88308 FT /note="Pfam match to entry PF00633 HHH, Helix-hairpin-helix FT motif., score 26.50, E-value 0.00061." FT CDS complement(88390..88770) FT /transl_table=11 FT /gene="SCO3353" FT /gene_synonym="SCE94.04c" FT /product="hypothetical protein" FT /note="SCE94.04c, unknown, len: 126aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X8L7" FT /protein_id="CAB40853.1" FT /translation="MKFSLRSVRNSYSPGQTPAFELTARNTSGGDCEVDLGPKHAVFTI FT TPASGDDAYWASDDCVEGAGSLRYRVTAGSGITYTVKWDRKPSAPECGTPPAGSAKAGT FT YLVEAKAAGFEKVQTSFVLKND" FT CDS 88781..89185 FT /transl_table=11 FT /gene="SCO3354" FT /gene_synonym="SCE94.05" FT /product="hypothetical proline-rich protein" FT /note="SCE94.05, unknown, proline-rich, len: aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X8L8" FT /protein_id="CAB40854.1" FT /translation="MQLGRLDPAGSASSAPTPVTAPPPPPPALPDPADPPPDSPPPDPE FT PFPALPPPEPDPEPEPLESPLPDSSRPPGAWLIAGPDPEGPGVIDGAGFLPLAPSSRPL FT PPSPPPETTIHVINSANRAKRDSSTALRRQ" FT CDS 89428..90354 FT /transl_table=11 FT /gene="SCO3355" FT /gene_synonym="SCE94.06" FT /gene_synonym="mutY" FT /product="putative adenine glycosylase" FT /note="SCE94.06, mutY, putative adenine glycosylase, len: FT 308 aa; previously partially sequenced therefore partially FT identical to TR:E1358524 (EMBL:AJ131213) MutY, putative FT adenine glycosylase from Streptomyces coelicolor (183 aa) FT fasta scores; opt: 1220, z-score: 1357.4, E(): 0, (100.0% FT identity in 183 aa overlap). Also similar to many others FT e.g. SW:MUTY_SALTY MutY, adenine glycosylase from FT Salmonella typhimurium (350 aa) fasta scores; opt: 500, FT z-score: 558.7, E(): 8.3e-24, (39.4% identity in 231 aa FT overlap). Contains Pfam match to entry PF00730 FT Endonuclease_3, Endonuclease III." FT /db_xref="GOA:Q9S6T7" FT /db_xref="HSSP:1KG2" FT /db_xref="InterPro:IPR003583" FT /db_xref="UniProtKB/TrEMBL:Q9S6T7" FT /protein_id="CAB40855.1" FT /translation="MTAPTKPSPGGPSDPAASGVPLHAPVIDWFDEHARDLPWRRPEAG FT AWGVMVSEFMLQQTPVSRVQPVYEQWLARWPRPADLAAEAPGEAVRAWGRLGYPRRALR FT LHGAAAAITERHGGDVPADHAQLLALPGIGEYTAAAVASFAYGQRHAVLDTNVRRVLAR FT AVTGVQYPPNATTAAERKLARALLPEEQERAARWAAASMELGALVCTAKKESCHRCPIA FT AQCAWRLAGKPAHDGPPRRGQTYAGTDRQVRGRLLAVLRDAAGPVPQAALDQVWQEPVQ FT RARALDGLVADGLVEPLADGLYRLPLS" FT misc_feature 89566..90105 FT /note="Pfam match to entry PF00730 Endonuclease_3, FT Endonuclease III, score 126.40, E-value 5.2e-34." FT CDS 90654..91187 FT /transl_table=11 FT /gene="SCO3356" FT /gene_synonym="SCE94.07" FT /product="ECF sigma factor" FT /note="SCE94.07, sigE, ECF sigma factor, len: 177 aa; FT previously sequenced therefore identical to TR:E1358525 FT (EMBL:AJ131213) SigE, ECF sigma factor from Streptomyces FT coelicolor (177 aa) fasta scores; opt: 1140, z-score: FT 1336.4, E(): 0, (100.0% identity in 177 aa overlap). Member FT of ECF sigma factors. Contains Prosite match to PS01063 FT Sigma-70 factors ECF subfamily signature. Also contains a FT possible helix-turn-helix region at 127-148aa (+3.34 SD)." FT /db_xref="GOA:P38133" FT /db_xref="InterPro:IPR013249" FT /db_xref="UniProtKB/Swiss-Prot:P38133" FT /protein_id="CAB40856.1" FT /translation="MGEVLEFEEYVRTRQDALLRSARRLVPDPVDAQDLLQTALARTYG FT RWETIEDKRLADAYLRRVMINTRTEWWRARKLEEVPTEQLPESPMDDATEQHADRALLM FT DVLKVLAPKQRSVVVLRHWEQMSTEETAAALGMSAGTVKSTLHRALARLREELVARDLD FT ARALEREERERCAA" FT misc_feature 90747..90842 FT /note="PS01063 Sigma-70 factors ECF subfamily signature." FT CDS 91244..91852 FT /transl_table=11 FT /gene="SCO3357" FT /gene_synonym="SCE94.08" FT /product="hypothetical protein" FT /note="SCE94.08, unknown, len: 202aa; previously sequenced FT therefore identical to TR:e1358526 (EMBL:AJ131213) FT hypothetical protein from Streptomyces coelicolor (202 aa) FT fasta scores; opt: 1347, z-score: 1386.9, E(): 0, (99.5% FT identity in 202 aa overlap). Note conflict in first codon, FT GTG rather than ATG." FT /db_xref="GOA:Q9ZEP5" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZEP5" FT /protein_id="CAB40857.1" FT /translation="MAVFVALGVSLAGCGTGGTGARDEGPAHADAVGGAGSASPAPAAK FT ASPSKAPDRVDAVRLVKADPKVSPEVKRELKPCVADEYPIDVSYGKVTDGSADDVVVNV FT LTCGDAVGVGSYVYREEDGAYQNVFKAEEPPVYAEIDRGDLVVTKQVYDKGDPVSSPSG FT ENVITYRWASDRFTEEYRTHNDYSKAAGNAPTPAPEPDS" FT CDS 91976..92680 FT /transl_table=11 FT /gene="SCO3358" FT /gene_synonym="SCE94.09" FT /gene_synonym="cseB" FT /product="two-component system response regulator" FT /note="SCE94.09, cseB, two-component system response FT regulator, len: 234 aa; previously sequenced therefore FT identical to TR:E1358527 (EMBL:AJ131213) CseB, response FT regulator, positive regulator of sigE transcription from FT Streptomyces coelicolor (234 aa) fasta scores; opt: 1529, FT z-score: 1731.2, E(): 0, (100.0% identity in 234 aa FT overlap). Also similar to many others eg. SW:PHOP_BACSU FT PhoP, response regulator of the phosphate regulon of FT Bacillus subtilis (240 aa) fasta scores; opt: 582, z-score: FT 665.4, E(): 9.4e-30, (41.2% identity in 233 aa overlap). FT Contains Pfam matches to entry PF00486 trans_reg_C, FT Transcriptional regulatory protein, C terminal and entry FT PF00072 response_reg, Response regulator receiver domain." FT /db_xref="GOA:Q9ZEP4" FT /db_xref="HSSP:1B00" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZEP4" FT /protein_id="CAB40858.1" FT /translation="MADQTHVLFVEDDDVIREATQLALERDGFAVTAMPDGLSGLESFR FT ADRPDIALLDVMLPGLDGVSLCRRIRDESTVPVIMLSARADSIDVVLGLEAGADDYVTK FT PFDGAVLVARIRAVLRRFGHAGGGDRTEGAGAAETGGVLTFGDLEVDTDGMEVRRAGRP FT VGLTPTEMRLLLEFSSAPGTVLSRDKLLERVWDYGWGGDTRVVDVHVQRLRTKIGQDRI FT ETVRGFGYKLKA" FT misc_feature 91988..92320 FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 129.20, E-value 7.3e-35." FT misc_feature 92459..92662 FT /note="Pfam match to entry PF00486 trans_reg_C, FT Transcriptional regulatory protein, C terminal, score FT 83.60, E-value 1.2e-23." FT CDS 92697..94220 FT /transl_table=11 FT /gene="SCO3359" FT /gene_synonym="SCE94.10" FT /product="putative sensory histidine kinase. Contains FT possible hydrophobic membrane spanning regions" FT /note="SCE94.10, cseC, sensory histidine kinase, len: 507 FT aa; previously sequenced therefore identical to TR:E1358528 FT (EMBL:AJ131213) CseC, sensory histidine kinase from FT Streptomyces coelicolor (507 aa) fasta scores; opt: 3298, FT z-score: 3217.4, E(): 0, (100.0% identity in 507 aa FT overlap). Also similar to many others eg. SW:AFQ2_STRCO FT sensor protein, part of a putative two-component regulatory FT system involved in secondary metabolism in Streptomyces FT coelicolor (535 aa) fasta scores; opt: 382, z-score: 378.4, FT E(): 9.2e-14, (29.8% identity in 413 aa overlap). Contains FT Pfam matches to entry PF00672 DUF5, Domain found in FT bacterial signal proteins and entry PF00512 signal, Signal FT carboxyl-terminal domain." FT /db_xref="GOA:Q9ZEP3" FT /db_xref="InterPro:IPR005467" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZEP3" FT /protein_id="CAB40859.1" FT /translation="MRGFFRQRRSVSPPGHPYDRTGPGEHAGPGARTGPGGRPRVLGVR FT GLRARGIRTGLRWKLSAAIALVGALVAIALSLVVHNAARVSMLDNARDLADDRVLIAQR FT NYELSGRQNFPNAQIDDPALPPELRRKIDAGRRATYVSERPDGVTDIWAAVPLKDGHVM FT SLHSGFTDRSADILSDLDQALVIGSIAVVLGGSALGVLIGGQLSRRLREAAAAANRVAS FT GEPDVRVRDAIGGVVRDETDDVARAVDAMADALQQRIEAERRVTADIAHELRTPVTGLL FT TAAELLPPGRPTELVLDRAKAMRTLVEDVLEVARLDGASERAELQDIMLGDFVSRRVAA FT KDPAVEVRVIHESEVTTDPRRLERVLFNLLANAARHGRSPVEVSVEGRVIRVRDHGPGF FT PEDLLAEGPSRFRTGSTDRAGRGHGLGLTIAAGQARVLGARLTFRNVRPAGAPAHIPAE FT GAVAVLWLPEHAPTNTGSYPMLPDRSKSGASSSARDMSREASQGMSRKP" FT misc_feature 93246..93467 FT /note="Pfam match to entry PF00672 DUF5, Domain found in FT bacterial signal proteins, score 39.60, E-value 7.2e-08." FT misc_feature 93507..94097 FT /note="Pfam match to entry PF00512 signal, Signal FT carboxyl-terminal domain, score 58.20, E-value 1.8e-13." FT CDS complement(94250..95083) FT /transl_table=11 FT /gene="SCO3360" FT /gene_synonym="SCE94.11c" FT /product="hypothetical protein" FT /note="SCE94.11c, unknown, len: 277aa; previously sequenced FT therefore identical to TR:E1358529 (EMBL:AJ131213) FT hypothetical protein from Streptomyces coelicolor (277 aa) FT fasta scores; opt: 1897, z-score: 2249.5, E(): 0, (99.6% FT identity in 277 aa overlap)." FT /db_xref="InterPro:IPR002575" FT /db_xref="UniProtKB/TrEMBL:Q9ZEP2" FT /protein_id="CAB40860.1" FT /translation="MEPAELRRAVEAGRTAASEQGLRADEVVVVHNSDRVVLRLLPCDV FT LARVAPPGHLSDSAFEVEVAHRLTDAGAPVGRLDPRTDPRVQVRDTFAVSLWTYYPPVG FT PEIAPADYADALMRHHAALRRIDVDAPHFSDRVAVALTGVDDRERSPELSESDRGFLRD FT ALSGLSAEIGADPARDQLLHGEPHPGNLLNTRQGPLFVDLATCCRGPVEFDLAHGPEEA FT AEHYAGADQALTHRCRALNWALFAAWRWRRDDQMPDREHWRAEGLDRVRAALDRI" FT CDS complement(95175..95627) FT /transl_table=11 FT /gene="SCO3361" FT /gene_synonym="SCE94.12c" FT /product="putative AsnC-family transcriptional regulator" FT /note="SCE94.12c, lrpA, probable AsnC-family FT transcriptional regulator, len: 150a a; previously FT sequenced therefore identical to TR:E1358530 FT (EMBL:AJ131213) LrpA, putative transcriptional regulator FT from Streptomyces coelicolor (150 aa) fasta scores; opt: FT 953, z-score: 1220.9, E(): 0, (100.0% identity in 150 aa FT overlap). Also similar to many amino acid responsive FT regulators e.g. TR:O33467 (EMBL:D89015) MdeR, FT transcriptional regulator from Pseudomonas putida (159 aa) FT fasta scores; opt: 380, z-score: 494.5, E(): 3.1e-20, FT (40.0% identity in 150 aa overlap). Contains Pfam match to FT entry PF01037 ASNC_trans_reg, AsnC family. Also contains a FT possible helix-turn-helix at 19-40aa (+4.10 SD)." FT /db_xref="GOA:Q9ZEP1" FT /db_xref="InterPro:IPR019888" FT /db_xref="UniProtKB/TrEMBL:Q9ZEP1" FT /protein_id="CAB40861.1" FT /translation="MDDVDRQILAELQKDGRLTLTELAERVRLSVSPCHRRLRALERSG FT AITGYHAALNAPALGLGFEALVFVTMRYEDRQTVAAFEAAVTEIPHVLQAQRLFGDPDY FT LLRVVTRDLEAYRRLYDERLASLPGVQRLSSTLVMANLVEARPLPL" FT misc_feature complement(95244..95555) FT /note="Pfam match to entry PF01037 ASNC_trans_reg, AsnC FT family, score 111.00, E-value 2.3e-29." FT CDS 95746..96381 FT /transl_table=11 FT /gene="SCO3362" FT /gene_synonym="SCE94.13" FT /product="putative membrane protein" FT /note="SCE94.13, putative membrane protein, len: 211 aa; FT weakly similar to many eg. SW:YRHP_BACSU hypothetical FT protein located close to sigma factor genes in Bacillus FT subtilis (210 aa) fasta scores; opt: 192, z-score: 222.0, FT E(): 4.7e-05, (25.0% identity in 164 aa overlap). Contains FT a possible membrane spanning hydrophobic regions" FT /db_xref="GOA:Q9X8L9" FT /db_xref="InterPro:IPR001123" FT /db_xref="UniProtKB/TrEMBL:Q9X8L9" FT /protein_id="CAB40862.1" FT /translation="MAGIGAFWSVSFLLVLVPGADWAYAITAGLRHRSVLPAVGGMLSG FT YVLLTAVVAAGLATAVAGSPTVLTALTAAGAAYLIWLGATTLARPAAPRAEEGDQGDGS FT GSLVGRAARGAGISGLNPKALLLFLALLPQFAARDADWPFAAQIVALGLVHTANCAVVY FT TGVGATARRILGARPAVATAVSRFSGAAMILVGALLLVERLLAQGPTH" FT CDS 96392..96835 FT /transl_table=11 FT /gene="SCO3363" FT /gene_synonym="SCE94.14" FT /product="putative acetyltransferase" FT /note="SCE94.14, possible acetyltransferase, len: 147aa; FT weakly similar to many eg. SW:PAT_STRHY phosphinothricin FT acetyltransferase from Streptomyces hygroscopicus (183 aa) FT fasta scores; opt: 116, z-score: 157.5, E(): 0.19, (27.9% FT identity in 136 aa overlap). Contains Pfam match to entry FT PF00583 Acetyltransf, Acetyltransferase (GNAT) family." FT /db_xref="GOA:Q9X8M0" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9X8M0" FT /protein_id="CAB40863.1" FT /translation="MADWGVRPASTGDVEAVAELRALVLQADLERLGRYDARRVRQRLR FT DGFVPAHTRVIEVDGTFAGCVALRPAEDAHWLEHFYLDPRVQGGGIGTAVLRELLERCD FT RGGTVVRLNVLRGSPAQRLYERHGFAVESEDPVDVFMVRAPVA" FT misc_feature 96407..96781 FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 61.80, E-value FT 1.5e-14" FT CDS 96842..97294 FT /transl_table=11 FT /gene="SCO3364" FT /gene_synonym="SCE94.15" FT /product="hypothetical protein" FT /note="SCE94.15, unknown, len: 150aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X8M1" FT /protein_id="CAB40864.1" FT /translation="MGIRIEAEVSFPANNEVERVLGMAETVGEPVTVTFEWEGGRPLLH FT GVLVPAATLALWEHWAPTAYPAGDRAEGPELAHPEEFGPFTLFRRRVGGRTAVARDGSV FT VAELLDPAEAHWLEDKARNVRQGFMDPKQKAAFEEFLARQAARGEQ" FT CDS complement(97464..98306) FT /transl_table=11 FT /gene="SCO3365" FT /gene_synonym="SCE94.16c" FT /product="conserved hypothetical protein" FT /note="SCE94.16c, unknown, len: aa; similar to others from FT Streptomyces coelicolor eg. TR:E1370777 (EMBL:AL035212) FT possible DNA binding protein (303 aa) fasta scores; opt: FT 420, z-score: 512.3, E(): 3.2e-21, (32.5% identity in 265 FT aa overlap)." FT /db_xref="GOA:Q9X8M2" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q9X8M2" FT /protein_id="CAB40865.1" FT /translation="MANIQSLDPTASPLDYYGWELRRQREAHGLKQGQLGDIIFCTGSL FT VGQIETTKKVPTRDFSERVDAALGTDGLFSRLIGLVLRSQLPTWFQPYAEMEAKAAYIS FT TYQAQLVYGLLQTEEYARAVLATGKPGQLDSLLAARMERQRILAWEKPPVALVILDEAV FT LHRPIGGDDVMWRQLAHLLEFTNHRWMRIQVLPLTSGEHPGLAGAFNILRFEDHPDVFY FT TEDMMSGHMTANPETIKEASLNYAHLQADALSVKDSAALIARVMEERYADRTERDPVA" FT CDS complement(98894..100489) FT /transl_table=11 FT /gene="SCO3366" FT /gene_synonym="SCE94.17c" FT /product="putative exporter" FT /note="SCE94.17c, possible exporter, len: 531aa; similar to FT many export proteins eg. TR:G4240426 (EMBL:AF080235) FT antibiotic transporter landomycin biosynthesis cluster of FT Streptomyces cyanogenus S136 (517 aa) fasta scores; opt: FT 1848, z-score: 1973.8, E(): 0, (55.2% identity in 511 aa FT overlap). also similar to TR:E1370405 (EMBL:AL035161) FT putative efflux protein from Streptomyces coelicolor (815 FT aa) fasta scores; opt: 1622, z-score: 1730.4, E(): 0, FT (46.1% identity in 518 aa overlap). Contains Pfam match to FT entry PF00083 sugar_tr, Sugar (and other) transporter. Also FT contains several probable membrane spanning hydrophobic FT regions." FT /db_xref="GOA:Q9X8M3" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9X8M3" FT /protein_id="CAB40866.1" FT /translation="MAEKTEAATGGAGAGKQPRSVRVVLLALMIAMMLAMLDNMIIGTA FT MPTIVGELGGLEHLSWVVTAYTLATAASTPLWGKLGDMYGRKGVFMTSIVIFLAGSALS FT GMAQDMGQLIGFRAVQGLGAGGLMVGVMAIIGDLIPPRERGKYQGMIAGVMALSMIGGP FT LVGGTITDHWGWRWSFYINIPLGVIALIAISAVLHLPKKRSEARIDYLGAALLTIGITA FT IVLVTTWGGTEYAWTSARIMELIGIGVAALVGFVFWQTRAAEPILPLHIFRSRNFTLMS FT VIGFIVGFVMFGATLFLPLYQQSVQGASATNSGLLLLPMLGAMLVTSMVAGRVTTSTGR FT YKIFPVAGGALMTVGLYLLSTMDTDTTRFTSGLYMAVVGLGMGCLMQITMLVAQNSVEM FT KDMGVASSSTTLFRTLGSSFGVAIMGALFNNRVQDVMAERAAGSGAKATEQSATLTADA FT LNALPAAIRDAYQHAVSAGTHTAFLLGSAVAVLALVASFFVKEVPLKGAGPKAADAPAD FT GDPATAKAPVTEAV" FT misc_feature complement(99281..100423) FT /note="Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter, score -81.20, E-value 0.0036." FT CDS 100648..101235 FT /transl_table=11 FT /gene="SCO3367" FT /gene_synonym="SCE94.18" FT /product="putative tetR-family regulator" FT /note="SCE94.18, possible tetR-family regulator, len: 195 FT aa; similar to many regulators e.g. TR:G4240425 FT (EMBL:AF080235) LanK from Streptomyces cyanogenus S136 (192 FT aa) fasta scores; opt: 584, z-score: 737.3, E(): 0, (51.4% FT identity in 185 aa overlap). Contains Pfam match to entry FT PF00440 tetR, Bacterial regulatory proteins, tetR family FT and Prosite match to PS01081 Bacterial regulatory proteins, FT tetR family signature. Also contains a probable FT helix-turn-helix at 43-55aa (+5.78 SD)." FT /db_xref="GOA:Q9X8M4" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9X8M4" FT /protein_id="CAB40867.1" FT /translation="MNGTKQQRRRGDTRQRIQDVALGLFAEQGYEKTSLREIAESLDVT FT KAALYYHFKTKEEILVSIFEDLSRPLEDLIEWGREQPHTLETKQEIIRRYSEALAGAAP FT LFRFMQENQATVRDLRIGELFKHRMFGLRDILMDPEADLVDQVRCISALFTLHAGMFVL FT RDLEGDPEEQRAAVLEVATDLITQAHRGAAGA" FT misc_feature 100696..100836 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 62.80, E-value FT 1.1e-15." FT misc_feature 100732..100824 FT /note="PS01081 Bacterial regulatory proteins, tetR family FT signature." FT CDS complement(101269..101955) FT /transl_table=11 FT /gene="SCO3368" FT /gene_synonym="SCE94.19c" FT /product="putative peptidase (putative secreted protein)" FT /note="SCE94.19c, possible peptidase (putative secreted FT protein), len: 228 aa; similar to SW:ALE1_STACP FT glycylglycine endopeptidase from Staphylococcus capitis FT EPK1 (362 aa) fasta scores; opt: 329, z-score: 324.3, E(): FT 9.5e-11, (38.9% identity in 180 aa overlap). Contains FT possible N-terminal region signal peptide sequence" FT /db_xref="GOA:Q9X8M5" FT /db_xref="InterPro:IPR002886" FT /db_xref="UniProtKB/TrEMBL:Q9X8M5" FT /protein_id="CAB40868.1" FT /translation="MFPRVTSRSSRTTIRTRAAVMAAGLGASVALGAGVAAATGTTAAS FT STTAAASAVEAQAAAQAKAAKAEKAAASAKKSTTAKKTATKKKAASWVDPVKKYELSAS FT FAQNGGMWAHKHSGQDFAVPIGTNVVAAHGGTVVKAGGNGAGDGPAYGNAIVIKHGNGT FT YSQYAHLSRINVKIGQIVKTGQSIAKSGNTGNSSGPHLHFEIRTTPNYGSAVDPVAFLR FT GKGVTV" FT CDS 102354..104942 FT /transl_table=11 FT /gene="SCO3369" FT /gene_synonym="SCE94.20" FT /product="putative large ATP-binding protein" FT /note="SCE94.20, possible large ATP-binding protein, len: FT 862aa; contains Prosite match to PS00017 ATP/GTP-binding FT site motif A (P-loop). Similar to two closely neighbouring FT genes SCE94.23 and SCE94.21 suggesting local duplication FT fasta scores; SCE94.23 opt: 1840, z-score: 1675.4, E(): 0, FT (48.9% identity in 839 aa overlap), SCE94.21 opt: 789, FT z-score: 717.7, E(): 5e-35, (44.7% identity in 877 aa FT overlap)." FT /db_xref="GOA:Q9X8M6" FT /db_xref="InterPro:IPR007111" FT /db_xref="UniProtKB/TrEMBL:Q9X8M6" FT /protein_id="CAB40869.1" FT /translation="MVDVTALGARVASSAVVPLVRRLFVRDGPGAGLVDRPVRISALVS FT FRGEKRNVTPEDVDKIAGELVRRALTSAGPGEEPVDAAEAAAVKDALARTLARLGEITV FT EDYEAVGLGPERFARELRAGVPLAPYGLGEGGTLLYERLLHTASLHILNFLTQRSTYVA FT RQQTVQTQQLARLVRAVDVLLERLPSQSAEDAGFEERYADHVAARYGTLTIYGLDAGTR FT EWPLDTAYLSLEATRPRAGRDGRRDPEYAAVAAEQVLAGHDQVFLRGVAGSGKTTLVQW FT LAVTAAGRVYDHGLTHLIGRVPFVLPMRRIVRPGAELPVPGDFLRAVGCPVAGEQPPGW FT VERVLRARRGVLLVDGIDEIAQDRRAAARRWLRELVRAFPGNLWLVTSRPSAVPEAWLA FT AEGFSELVLAPMGRDGVATFVRRWHRAAEVAESVGESLLASVRSTSELNGLATNPLMCG FT MLCALHRDRRGFLPQDRRSLYEAALTMLLERRDRERELHGSDGVRLAYATQVQLLQKLA FT WWLIRNSRQEMDRDEALGIVDRALPALNLADAGGEEVYRALLLRSGLLREPAEGRVDFL FT HRTFQDYLGARLAVQEMDFDLLVNHAHLDEWDDVILLALAHARPKEAEQMLRRLTELGT FT PRGTLLAAAGLRYAAEVAPTVRGRVEDGLATHVPPTTFEAAREVARAGGDLVLGLLPGP FT EDGIDDSTAARVVHTAVSVGSEAALQFLSRFREHTGADVQEFLATSWNRFDREQYAREI FT LAHLPRQRAVEVATTDDLHVLRSLGGWGHIFVRGAYRVDDLTELVVPERLTHLTLEAPH FT PVEGLAWLTAFPRLRTVSVLADLDEAVARQVPDGVELQGPFASLSSRPQG" FT misc_feature 103158..103181 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 104952..107537 FT /transl_table=11 FT /gene="SCO3370" FT /gene_synonym="SCE94.21" FT /product="putative large ATP-binding protein" FT /note="SCE94.21, possible large ATP-binding protein, len: FT 861 aa; contains Prosite match to PS00017 ATP/GTP-binding FT site motif A (P-loop). Similar to two closely neighbouring FT genes SCE94.23 and SCE94.20 suggesting local duplication; FT fasta scores: SCE94.23 opt: 984, z-score: 883.6, E(): 0, FT (43.6% identity in 857 aa overlap), SCE94.20 opt: 789, FT z-score: 709.4, E(): 1.4e-34, (44.7% identity in 877 aa FT overlap)" FT /db_xref="GOA:Q9X8M7" FT /db_xref="InterPro:IPR007111" FT /db_xref="UniProtKB/TrEMBL:Q9X8M7" FT /protein_id="CAB40870.1" FT /translation="MDAVVRTPSRLAAPLVHRLFRDPARPPVFSEPVPGLVSWRGARAT FT ATPDEVHRTAADLVHLAAERHAAPTAELAPVVDVLARTLLAIAEVDVTDADAVRLGPQD FT YARRLRGAVQGADRELSPDAAWFHDALLVSVCLHVLHHLVRRSAYLQRQLPGRASRIAQ FT LVDLGDAEAAARHAERPEEDVAFEAEYAEWVARRHGWLTIVGVDFPNAPDRWPLEETYL FT SLEAEERSGGVGGTEDEQRTVLLADRALEDHDRVLLRGGAGSGKTTLVQWLAVAAAREG FT SRVPFVLPVRRFAREGFPAPDDFLHAVRHPLADRAPEGWVVRTLLAGRALLLVDGIDEA FT PEKTRGELRDRLRRLLRVFSGNGCLVTSRPSAVSEGWLSGGGLAEEDFVELSLAPMSRD FT RVTRFIRDWHSAARLDEQSRSPGPRERERERSTLDEYEQRLLHSVRIYRELRQLATNPL FT MCGLICALNRDRAGSLPSGRKELYDAALEMLLQRRDPERDVLYADDVRLQQSTRERLLQ FT KLAHAMLEEDASELTRERAVGILDAALPAMPAARAQGDGAKIFRHLLHRTGLLRERSGE FT SVDFVHRTFQDYLAAKEIVARGRFPTLVDHAHQSEWEEVIRMAAAHARPEECAEFLERL FT LAPAPALRRPQINHRRLMAAACLDHVTELDPAVQRLVHDRTKNLVRPTTELAARGLGWV FT GPIVLELLPDPGQVPDDRQALLLACTATRVQDDAAIDYLVRLRSRAALPVRTELARGWR FT HFDTERYAQEIIAHLDPDGLYFPVADTAELAALRELGGRPRIQVAGVMRAEELLAGLLP FT DQLTHLWLNAELPDTDVSWLSGFPRLRVLRVNPRLPRVRNVPDGVEITA" FT misc_feature 105729..105752 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 107608..108327 FT /transl_table=11 FT /gene="SCO3371" FT /gene_synonym="SCE94.22" FT /product="hypothetical protein" FT /note="SCE94.22, unknown, len: 239aa;" FT /db_xref="GOA:Q9X8M8" FT /db_xref="InterPro:IPR014403" FT /db_xref="UniProtKB/TrEMBL:Q9X8M8" FT /protein_id="CAB40871.1" FT /translation="MHATTLPSGIRAGRHERTPPPMTVQTGQTRQTRSRTWTRVTGTAA FT VVAAALTATVTPSVAAPAETPPASVTAAAADVGYDTWQRDCRAVMDAALPYLKERIAGS FT APGEKQAVVLDIDNTSLETDFGFSYPQPANRPVLEVAEYAQEHGVALFFVTARPGIIEA FT PTEWNLAHAGYESSGLYVRGFLDLFKDVAEYKTEQRAEIESKGYTIIANIGNSASDLSG FT GHAEKTFKLPDYDGQLS" FT CDS 108371..111403 FT /transl_table=11 FT /gene="SCO3372" FT /gene_synonym="SCE94.23" FT /product="putative large ATP-binding protein" FT /note="SCE94.23, possible large ATP-binding protein, len: FT 1010aa; contains Prosite match to PS00017 ATP/GTP-binding FT site motif A (P-loop). Similar to two closely neighbouring FT genes SCE94.20 and SCE94.21 suggesting local duplication FT fasta scores; SCE94.20 opt: 1840, z-score: 1632.1, E(): 0, FT (48.9% identity in 839 aa overlap), SCE94.21 opt: 984, FT z-score: 872.5, E(): 0, (43.8% identity in 857 aa FT overlap)." FT /db_xref="GOA:Q9X8M9" FT /db_xref="InterPro:IPR007111" FT /db_xref="UniProtKB/TrEMBL:Q9X8M9" FT /protein_id="CAB40872.1" FT /translation="MEPAVLGGKLASSLVTPLVKKLFVTGGPGAGLVDRPVRLDRLVSF FT RGERRSLGEREVRGLAGKLVGAALDSPGEPPFPRDETEAVADALAARLLALGDLDMDDV FT QAVRLGHGELAARLRRQAAGSGDGLSTDARYFLDSATEWACLHVLEFFTRRSTFVARTL FT VEQTRGQAELIAKVDELISRVPRPDARDTAFERRYRSYVAEQHNRITIYGIDLRDSPDR FT WPLEVAYLSLEATAEEERTAALPGEYTDPERTVRLAAEDALRTRDRVLLRGDAGSGKTT FT LVQWLAVTAARDGDRVPYVLPLRTLTRAGALPSPAAFLTAVGCPLTPPEGWAERVLNAG FT RGLVLVDGLDEIPAADRNRTRDWLLGLVRAFPGNRWLLTSRPTAVRPDWLAAEGFRELA FT LTPMRQDDVATFVRRWHAAAEAPEFEVRLLDSLRTKRDLARLATNPLMCGLICALHRER FT RGYLPTGRKELYDAALTMLLARRDRERGMDAVELGEEAQLELLQRLAYALVLSGRTEMS FT VETAEGIVERALPSVASAAGQGDAATVLRALVLRSGLLRRPDEGSLDFVHRTFQDYLGA FT RYAVEEGHLDVIAGRAGDSQWEDVVRMAVAHARPGERAMLLRRLLAEDTPRLTLLALAC FT LEHATALDPAVRAEVEARAGALIPPGSTEEAKALAEAGPLVLELLPGPEGLTDAQAHGV FT AVAASLLAVHEPTGALAVLRRYREHPSLDVRRQLVGTWGRFEARAYATEVLDHLDRTAL FT FLTCRTKAQREALPVMGPWTHLTFLGAHRTTEIIDCVAEPGAVEELQLVNNSEVTELGA FT LSAFTSLRLLLIDCEPVRDLGPLTSLPLTALLINRAAGLTGLSDLSSVTHLTVARRLPG FT TRLTASLPAAAPLQYLYLGDDAIAGTGLRGLSHWETLQALYLSPATPLTAEDWAEIRRL FT PQLALLYLHGSLFPDSIEAMPTLPGVDGLGLIALDGGQDISVLAPRLPDVRTVTLQAAP FT GASLDGARLTALFPDADVTLE" FT misc_feature 109187..109210 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS complement(111481..114006) FT /transl_table=11 FT /gene="SCO3373" FT /gene_synonym="SCE94.24c" FT /product="putative Clp-family ATP-binding protease" FT /note="SCE94.24c, probable Clp-family ATP-binding protease, FT len: 841aa; highly similar to many egs. SW:MECB_BACSU FT MecB/ClpC pleiotropic regulator controlling competence gene FT expression and growth at high temperature in Bacillus FT subtilis (810 aa) fasta scores; opt: 3266, z-score: 3278.7, FT E(): 0, (61.6% identity in 805 aa overlap) and TR:Q48760 FT (EMBL:U40604) ClpC ATPase required for stress tolerance and FT in vivo survival of Listeria monocytogenes (825 aa) fasta FT scores; opt: 3204, z-score: 3216.3, E(): 0, (61.2% identity FT in 804 aa overlap). Also similar to TR:O69936 FT (EMBL:AL023861) clp protease ATP binding subunit from FT Streptomyces coelicolor (842 aa) fasta scores; opt: 2357, FT z-score: 2283.1, E(): 0, (48.9% identity in 829 aa FT overlap). Contains Pfam match to entry PF00495 clpA_B, FT Chaperonin clpA/B and two Prosite match to PS00017 FT ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q9S6T8" FT /db_xref="HSSP:1JBK" FT /db_xref="InterPro:IPR019489" FT /db_xref="UniProtKB/TrEMBL:Q9S6T8" FT /protein_id="CAB40873.1" FT /translation="MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVA FT AKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIG FT TEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKETATAGGPAEGTPST FT SLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVV FT EGLAQAIVKGEVPETLKDKHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILF FT IDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGATTLDEYRKHLEKDAALERRFQP FT IQVAEPSLPHTIEILKGLRDRYEAHHRVSITDEALVQAATLADRYISDRFLPDKAIDLI FT DEAGSRMRIRRMTAPPDLREFDEKIAGVRRDKESAIDSQDFEKAASLRDKEKQLLAAKA FT KREKEWKAGDMDVVAEVDGELIAEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQ FT KDAVKALSKAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELSKALAEFLFGDEDALISL FT DMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLL FT QILEDGRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAAAGDTKSNYERMKNKV FT QDELKQHFRPEFLNRVDDVVVFPQLSQDDILQIVDLMIQKVDERLKDRDMGIELSQSAK FT ELLSKRGYDPVLGARPLRRTIQREVEDSLSEKILFGELRPGHIVVVDTEGEGDAATFTF FT RGEEKSTLPDVPPIEQAAGGAGPNLSKEA" FT misc_feature complement(111610..112587) FT /note="Pfam match to entry PF00495 clpA_B, Chaperonin FT clpA/B, score 700.90, E-value 6e-207." FT misc_feature complement(112339..112362) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature complement(113350..113373) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 114448..115149 FT /transl_table=11 FT /gene="SCO3374" FT /gene_synonym="SCE94.25" FT /product="hypothetical proline-rich protein" FT /note="SCE94.25, unknown, proline-rich, len: 702 aa" FT /db_xref="UniProtKB/TrEMBL:Q9X8N0" FT /protein_id="CAB40874.1" FT /translation="MVGASHSVPLAPASPVVPSPRRPTGNGGSARERTRWWYESVLGWP FT TAPGEPVRLRTGIRFDVLDVPAAAGYATLERLGWSGRGPQGFPVAVRGERMLLLVAAGG FT AEELPGLLEWLEWGSLALDLTAVGADGLVEAPLAPVVPETRPAGPPPRPPGRDGVRGAA FT VWLRPPEPGCEAESSLPALSALGGAGTALDLVRLVRTLATQCHRVRLTADRSPRARPET FT RPMAPPVAGVG" FT CDS complement(115150..115485) FT /transl_table=11 FT /gene="SCO3375" FT /gene_synonym="SCE94.26c" FT /product="putative Lsr2-like protein" FT /note="SCE94.26c, Lsr2-like protein, len: 111 aa; similar FT to SW:LSR2_MYCLE surface antigen protein from Mycobacterium FT tuberculosis (112 aa) fasta scores; opt: 358, z-score: FT 416.0, E(): 7.4e-16, (55.4% identity in 112 aa overlap)." FT /db_xref="UniProtKB/TrEMBL:Q9X8N1" FT /protein_id="CAB40875.1" FT /translation="MAQKVQVLLVDDLDGGEADETVTFALDGKTYEIDLTTANADKLRG FT LLDPYLKGGRRTGGRASGGRGKARAASGGSQDTAAIRAWAKENGWDVNDRGRVPAKVRE FT AYEQANG" FT CDS complement(115761..116270) FT /transl_table=11 FT /gene="SCO3376" FT /gene_synonym="SCE94.27c" FT /product="putative acetyltransferase" FT /note="SCE94.27c, possible acetyltransferase, len: 169aa; FT similar to hypothetical proteins eg. TR:O33289 FT (EMBL:AL008967) from Mycobacterium tuberculosis (174 aa) FT fasta scores; opt: 656, z-score: 842.4, E(): 0, (60.4% FT identity in 164 aa overlap). Also some similarity to FT SW:ARGA_ECOLI ArgA, amino-acid acetyltransferase from FT Escherichia coli (443 aa) fasta scores; opt: 192, z-score: FT 248.7, E(): 1.5e-06, (29.0% identity in 138 aa overlap). FT Contains Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family." FT /db_xref="GOA:Q9X8N2" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9X8N2" FT /protein_id="CAB40876.1" FT /translation="MSNAISVRRARTRDVPDVRRLLDAYVRDRILLDKAMVTLYESIQE FT FWVAERDDNAEVVGCGALHVMWEDLAEVRTLAVKPGLKGAGVGHKVLEKLLDTARWLGV FT RRVFCLTFEVDFFGKHGFVEIGETPVDTDVYAELLRSYDEGVAEFLGLERVKPNTLGNS FT RMLLHL" FT misc_feature complement(115902..116252) FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 35.40, E-value FT 1.3e-06." FT CDS complement(116280..116654) FT /transl_table=11 FT /gene="SCO3377" FT /gene_synonym="SCE94.28c" FT /product="hypothetical protein" FT /note="SCE94.28c, unknown, len: 124 aa; similar to FT hypothetical proteins eg. TR:O32909 (EMBL:AL008609) from FT Mycobacterium leprae (142 aa) fasta scores; opt: 215, FT z-score: 273.2, E(): 6.6e-08, (41.9% identity in 105 aa FT overlap)." FT /db_xref="GOA:Q9X8N3" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9X8N3" FT /protein_id="CAB40877.1" FT /translation="MTRVWKWNRPVTVREVLEDLQQERSIAYTTVMTVLDNLHQKGWVR FT RESEGRAYRYEAVSTRAAYAAALMNDAWSQSDNPAAALVAFFGMMSEEQRQALADAIRI FT VQGPETPAPGPGAVADGGER" FT CDS complement(116813..116992) FT /transl_table=11 FT /gene="SCO3378" FT /gene_synonym="SCE94.29c" FT /product="putative small membrane protein" FT /note="SCE94.29c, putative small membrane protein, len: 47 FT aa. Contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9X8N4" FT /protein_id="CAB40878.1" FT /translation="MDYVSALLPPAVMAVFFIGLIRVIVKTQGGANKAKEDAVVDAALA FT RAEGARQQSPHPEA" FT CDS complement(117016..117642) FT /transl_table=11 FT /gene="SCO3379" FT /gene_synonym="SCE94.30c" FT /product="hypothetical protein" FT /note="SCE94.30c, unknown, proline-rich, len: 208aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X8N5" FT /protein_id="CAB40879.1" FT /translation="MPTPYGPRGGMAFGAQELRVLRRALALALNPSPVSAQEAQDCLHL FT ADSLDEAMREGARLRAFLLADLARYRAALPGTATGYLALLDEALGAGHRPDADDLAALG FT ALRGTPAAAALLARCAPETPTAPTASTVPLPAARARTRLHAVPGGRQSGKEPPQKPAAK FT PSPRPAPAPATPKRPVPTPGEVFPPRKPAPPAPPAPDSRHHLAAG" FT CDS complement(118076..118873) FT /transl_table=11 FT /gene="SCO3380" FT /gene_synonym="SCE94.31c" FT /product="conserved hypothetical protein" FT /note="SCE94.31c, unknown, len: 265aa; similar to FT hypothetical proteins eg. TR:O06282 (EMBL:Z95557) from FT Mycobacterium tuberculosis (272 aa) fasta scores; opt: 884, FT z-score: 1015.5, E(): 0, (51.9% identity in 268 aa FT overlap)." FT /db_xref="GOA:Q9X8N6" FT /db_xref="InterPro:IPR004619" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8N6" FT /protein_id="CAB40880.1" FT /translation="MLLTIDVGNTHTVLGLFDGEDIVEHWRISTDSRRTADELAVLLQG FT LMGMHPLLGDELGDGIDGIAICATVPSVLHELREVTRRYYGDVPAVLVEPGVKTGVPIL FT TDHPKEVGADRIINAVAAVELYGGPAIVVDFGTATTFDAVSARGEYIGGVIAPGIEISV FT EALGVKGAQLRKIEVARPRSVIGKNTVEAMQSGIVYGFAGQVDGVVNRMARELADDPDD FT VTVIATGGLAPMVLGESSVIDEHEPWLTLMGLRLVYERNVSRM" FT CDS complement(118879..119868) FT /transl_table=11 FT /gene="SCO3381" FT /gene_synonym="SCE94.32c" FT /gene_synonym="nadC" FT /product="nicotinate-nucleotide pyrophophorylase" FT /note="SCE94.32c, nadC, nicotinate-nucleotide FT pyrophophorylase, len: 329 aa; similar to many e.g. FT SW:NADC_MYCTU NadC, nicotinate-nucleotide pyrophophorylase FT from Mycobacterium tuberculosis (285 aa) fasta scores; opt: FT 909, z-score: 1017.8, E(): 0, (57.3% identity in 267 aa FT overlap)." FT /db_xref="GOA:Q9X8N7" FT /db_xref="HSSP:1QPO" FT /db_xref="InterPro:IPR002638" FT /db_xref="UniProtKB/TrEMBL:Q9X8N7" FT /protein_id="CAB40881.1" FT /translation="MNPSDPTELPLASGGGCGDGCACGAETEEEAFMECGLDPALAALL FT LDSGLDPVEVEDIANVAIQEDLAGGVDVTTVATIPEDAVATADFTAREAGVVAGLRVAE FT AVLSVVCTDEFEVERHVEDGDRVAEGQKLLSVTTRTRDILTAERSALNLLCRMSGIASA FT TRAWADALDGTKAKVRDTRKTTPGLRGLEKFAVRCGGGVNHRMSLSDAALVKDNHVVAA FT GGVAEAFNAVRESFPEVPIEVEVDTLHQLREVVDAGADLILLDNFTPDECEEAVALVAG FT RAALEASGRLTLTNAKAYAATGVDYLAVGALTHSSPILDIGLDLRAAE" FT CDS complement(119874..121616) FT /transl_table=11 FT /gene="SCO3382" FT /gene_synonym="SCE94.33c" FT /gene_synonym="nadB" FT /product="L-aspartate oxidase" FT /note="SCE94.33c, nadB, L-aspartate oxidase, len: 580 aa; FT similar to many eg. SW:NADB_ECOLI NadB, L-aspartate oxidase FT from Escherichia coli (540 aa) fasta scores; opt: 1207, FT z-score: 1289.2, E(): 0, (42.9% identity in 531 aa FT overlap). Contains Pfam match to entry PF00890 FT FAD_binding_2, FAD binding domain and Prosite match to FT PS00017 ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q9X8N8" FT /db_xref="HSSP:1CHU" FT /db_xref="InterPro:IPR005288" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8N8" FT /protein_id="CAB40882.1" FT /translation="MTSTGIRLHAPAPGWAIAADVVVVGSGVAGLTAALRCESAGLRTV FT VVTKARLDDGSTRWAQGGVAAALGEGDTPEQHLDDTLVAGAGLCDQDAVRILVTEGPDA FT VRRLIATGAHFDESTEGGLALTREGGHHRRRIAHAGGDATGAEISRALVEAVRARGLRT FT VENALVLDLLTDAEGRTAGVTLHVMGEGQHDGVGAVHAPAVVLATGGMGQVFSATTNPS FT VSTGDGVALALRAGAEVSDLEFVQFHPTVLFLGSDAEGQQPLVSEAVRGEGAHLVDADG FT VRFMQGRHELAELAPRDIVAKAITRRMQEHGADHMYLDARHFGRTMWEHRFPTILAACR FT AHGIDPVTEPVPVAPAAHYASGGVRTDAHGRTTVPGLYACGEVACTGVHGANRLASNSL FT LEGLVYAERIAADIAAAHTAGTLHARVPAPLPHPDHSQHPRHPLLPPEARLTIQRIMTE FT GAGVLRSADSLARAADRLHGLHAEAREALHEHGKTSEPGVDTWEATNLLCVARVLVAAA FT ARREETRGCHWREDHADRDDTTWRRHVVVRLNPDRTLAVHTTDTPEFPPTVHGAQPTHR FT PQEQ" FT misc_feature complement(120138..120161) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature complement(120375..121268) FT /note="Pfam match to entry PF00890 FAD_binding_2, FAD FT binding domain, score 413.90, E-value 1.5e-120." FT CDS complement(121613..122626) FT /transl_table=11 FT /gene="SCO3383" FT /gene_synonym="SCE126.01c" FT /gene_synonym="SCE94.34c" FT /product="putative pantoate-amino acid ligase" FT /note="SCE126.01c, possible pantoate-amino acid ligase FT (fragment), len: >196 aa; region of similarity to many e.g. FT SW:PANC_ECOLI pantoate-beta-alanine ligase from Escherichia FT coli (283 aa) fasta scores; opt: 608, z-score: 695.7, E(): FT 1.9e-31, (52.3% identity in 195 aa overlap)." FT /note="SCE94.34c, possible pantoate-amino acid ligase FT (fragment), len: >176 aa; region of similarity to many e.g. FT SW:PANC_ECOLI pantoate-beta-alanine ligase from Escherichia FT coli (283 aa) fasta scores; opt: 189, z-score: 225.1, E(): FT 3.2e-05, (50.8% identity in 61 aa overlap)." FT /db_xref="GOA:Q9X844" FT /db_xref="HSSP:1MOP" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/Swiss-Prot:Q9X844" FT /protein_id="CAD55315.1" FT /translation="MTTPTPPVLLRTAGELHARVRRGRRAVVMTMGALHEGHATLIRTA FT RDIAGPDGEVVVTVFVNPLQFGAGEDLDRYPRTLDADLEIAGRAGADAVFAPAVDEVYP FT GGEPQVRVTAGPMGGRLEGASRPGHFDGMLTVVAKLLHLTRPDLALYGQKDAQQLALIR FT RMVRDLNFGVEIVGVPTVREEDGLALSSRNRYLSTAERRTALALSQALFAGLDRHAAQE FT ALCARAREVPATQARAEALSALGESRAAADAHAVATSAPGSATAVRDAARLVLDDAARA FT TPPLELDYLALVDPSDFTEIGDDHTGEAVLAVAARVGATRLIDNVHLTFGPLGAAS" FT CDS complement(122623..123885) FT /transl_table=11 FT /gene="SCO3384" FT /gene_synonym="SCE126.02c" FT /product="conserved hypothetical protein" FT /note="SCE126.02c, unknown, len: 420aa; similar to FT TR:O06279 (EMBL:Z95557) hypothetical protein from FT Mycobacterium tuberculosis (303 aa) fasta scores; opt: 683, FT z-score: 584.3, E(): 3.1e-25, (49.3% identity in 284 aa FT overlap)." FT /db_xref="GOA:Q9X845" FT /db_xref="InterPro:IPR019665" FT /db_xref="UniProtKB/TrEMBL:Q9X845" FT /protein_id="CAB40924.1" FT /translation="MNTTPQADPKDRPARLTVGVVGAGRVGPALAASLQLAGHRPVAVS FT GVSDASRRRAAALLPDVPLMTPAEVLQHAELVLLTVPDDALPGLVTGLAETGAVRPGQL FT LVHTSGRYGARVLDPALRAGALPLALHPAMTFTGTPVDVQRLAGCTFGVTAPEELRLAA FT EALVIEMGGEPEWIAEDRRPLYHAALALGSNHLITLVAQSMELLRTAGVTAPDRMLGPL FT LGASLDNALRSGDAALTGPVARGDAGTVAAHIVELREHAPQAVAGYLAMARATADRALD FT HGLLKPELAEDLLGVLAENAPGTSPTGAPAADAPAGPDRTPDAKTDPEGAPGPEDVPAP FT DGSTGPDGPTDAARGAATDGPAKDGPHRRKRTPDADADAGSEGAPAPEGTPDPDGPDGP FT TGPERPAGPTGPTGTDDGGAR" FT CDS 124086..125297 FT /transl_table=11 FT /gene="SCO3385" FT /gene_synonym="SCE126.03" FT /product="putative L-allo-threonine aldolase" FT /note="SCE126.03, possible lyase, len: 403aa; weakly FT similar to many eg. SW:LTAA_AERJA L-allo-threonine aldolase FT from Aeromonas jandaei DK-39 (338 aa) fasta scores; opt: FT 257, z-score: 293.4, E(): 5e-09, (31.4% identity in 255 aa FT overlap)." FT /db_xref="GOA:Q9X846" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:Q9X846" FT /protein_id="CAB40925.1" FT /translation="MSDTAEQEERAAPARPEAPPAQDEPAEQRDRRSRERRVAALRGAR FT RVLARPGFVTTLRERIALLDGAEELYDLDEPSDMYGNGVVEALEERTAALLGTEAAAFF FT PTGTMAQQVALRCWAGRTGNPVVALHGLGHPEQHERNAFSRVGGLHPVRLTDAPRPPTA FT DEVRGFEEPFGALMLELPLREAGYLLPTWEELTEVVEAARERDAVVHFDGARLWECTVH FT FGRPLAEIAGLADSVYVSFYKSLKGYGGGALAGPRTLVEEAKAWRHRYGGQVFQQFPTA FT LSALAGLERELPRLPSYVAHARVVAAALRASLAAAGLPWARVHPAVPHTHEFQVWLPCD FT PDAASEAALRQAEETGTMLFSQPWDAGGPGIALTEVSVGESGLEWTADDVRAAVADFAA FT RLTA" FT CDS 125469..125741 FT /transl_table=11 FT /gene="SCO3386" FT /gene_synonym="SCE126.04" FT /product="hypothetical protein" FT /note="SCE126.04, unknown, len: 90aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X847" FT /protein_id="CAB40926.1" FT /translation="MPLADDPPVVGAGRGRPGFTELPGPVGVEEVLLRDAHGGSPSQGD FT VAVGTGSAAAPVTPDCAGPRPAVASIDGGGQSAAALSVAACTMGA" FT CDS 125738..126844 FT /transl_table=11 FT /gene="SCO3387" FT /gene_synonym="SCE126.05" FT /product="putative transcriptional regulator" FT /note="SCE126.05, possible transcriptional regulator, len: FT 368aa; similar to many in a limited region which FT corresponds to the probable DNA-binding site eg. FT SW:SMTB_SYNP7 SmtB transcriptional repressor from FT Synechococcus sp. (Strain PCC7942) (122 aa) fasta scores; FT opt: 169, z-score: 204.8, E(): 0.00043, (37.0% identity in FT 92 aa overlap). Contains Pfam match to entry PF01022 HTH_5, FT Bacterial regulatory protein, arsR family." FT /db_xref="GOA:Q9X848" FT /db_xref="HSSP:1SMT" FT /db_xref="InterPro:IPR001845" FT /db_xref="UniProtKB/TrEMBL:Q9X848" FT /protein_id="CAB40927.1" FT /translation="MSVRIDITGLRPERVAVVPSPLAELGMALHALSEPGHHPGLQGWV FT TGVTARLDSHLADRMCEADFLWRTTFSDLFMPFAGVPGRSTLPGATLADDLDLLDKLSD FT EQFVDAALEFTCALPYSTGGVSALDDAEVRRRALDLAAARGPQQLRFSERLLADPPRIR FT DWLRQFARDCDEAFFAEAWSRLRHQLAADARRKTDLLRHKGLAEALAAVSPAVTLDEGA FT ARITVDKLGDGRSATADGGLLLVPTSLGWPHLMVLHRHDWQPVLHYPVGSPELASPPSV FT EQLTMRMTALSHPVRMRICRYLARSAYTTGELAQVHGMTAPEISRHLGVLKKAGLVTTR FT RRGRYVLHQLDVTVVARLGSDFLEGILR" FT misc_feature 126599..126832 FT /note="Pfam match to entry PF01022 HTH_5, Bacterial FT regulatory protein, arsR family, score 45.10, E-value FT 1.6e-09." FT CDS complement(126887..127528) FT /transl_table=11 FT /gene="SCO3388" FT /gene_synonym="SCE126.06c" FT /product="TmrB-like protein" FT /note="SCE126.06c, TmrB-like protein, len: 213aa; similar FT to SW:TMRB_BACSU tunicamycin resistance protein (binds FT tunicamycin) from Bacillus subtilis (197 aa) fasta scores; FT opt: 335, z-score: 416.0, E(): 7.3e-16, (38.9% identity in FT 203 aa overlap)." FT /db_xref="UniProtKB/TrEMBL:Q9X849" FT /protein_id="CAB40928.1" FT /translation="MDQRPLRGRQSIQSLPAHEIRRRLPGSVVCDPEHAGFGLRRMLPP FT ELREDFQDLVSWRQGVVEVLDLALTRHDGVVIAPMTVTDPGYFAETVGRLRELGHDVHH FT FSLLAARETVLRRLRERGPGHALRYVTGKAGQGSGPRRESWAVRQLDHCLERLAEPEFA FT EHLWTDHTTVPKTADRIAVLAGLTLKPNNEGALRTRMRQAGVGIRHIRVD" FT CDS complement(127589..128263) FT /transl_table=11 FT /gene="SCO3389" FT /gene_synonym="SCE126.07c" FT /product="putative two component system response regulator" FT /note="SCE126.07c, probable two component system response FT regulator, len: 224aa; similar to many, particularly others FT from Streptomyces coelicolor eg. TR:O86632 (EMBL:AL031155) FT putative two component regulator (222 aa) fasta scores; FT opt: 784, z-score: 897.1, E(): 0, (57.7% identity in 215 aa FT overlap). Also similar to SW:DEGU_BACSU transcriptional FT regulator protein DegU from Bacillus subtilis (229 aa) FT fasta scores; opt: 466, z-score: 538.0, E(): 1.2e-22, FT (37.2% identity in 223 aa overlap). Contains Pfam matches FT to entry PF00072 response_reg, Response regulator receiver FT domain and to entry PF00196 GerE, Bacterial regulatory FT proteins, luxR family. Also contains Prosite match to FT PS00622 Bacterial regulatory proteins, luxR family FT signature." FT /db_xref="GOA:Q9X850" FT /db_xref="HSSP:1RNL" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9X850" FT /protein_id="CAB40929.1" FT /translation="MAIRVMLVDDQVLLRTGFRMVLAAQPDMEVVAEAGDGVEALQVLR FT STAVDVVLMDVRMPKLDGVETTSRICVDPNAPKVLILTTFDLDEYAFSALKAGASGFML FT KDVPPGELLAAIRSVHSGDAVVAPSTTRRLLDRFAPMLPATGQEPRQKELQRLTERERE FT VMVLVAQGMSNGEIAARLVLSEATVKTHVGRILTKLGLRDRVQVVVLAYETGLVRAGGG FT QG" FT misc_feature complement(127607..127804) FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 93.20, E-value FT 5.3e-24." FT misc_feature complement(127670..127753) FT /note="PS00622 Bacterial regulatory proteins, luxR family FT signature." FT misc_feature complement(127916..128257) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 122.50, E-value 7.7e-33." FT CDS complement(128329..129534) FT /transl_table=11 FT /gene="SCO3390" FT /gene_synonym="SCE126.08c" FT /product="putative two component sensor kinase" FT /note="SCE126.08c, possible two component sensor kinase, FT len: 401 aa; similar to many, often from Streptomyces FT coelicolor e.g. TR:O88024 (EMBL:AL031107) putative two FT component sensor (405 aa) fasta scores; opt: 718, z-score: FT 796.4, E(): 0, (42.2% identity in 313 aa overlap). Also FT similar to SW:DEGS_BACBR sensor protein DegS from Bacillus FT brevis (386 aa) fasta scores; opt: 320, z-score: 358.3, FT E(): 1.2e-12, (30.1% identity in 236 aa overlap). FT N-terminal half contains possible membrane spanning FT hydrophobic regions followed by a possible coiled-coil at FT approx. aa 180" FT /db_xref="GOA:Q9X851" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9X851" FT /protein_id="CAB40930.1" FT /translation="MQRLYDFLRRHPTGVDSFWAFVVLGVSLVSAATPGTRADGTDNVA FT LIVPFVVLLSVVIALRQRAPERMLLLAVVLGLGQLAFDVSTMPADFAFLVIIYTVAATG FT ARWASRTALATGLCAAPLAQLRWSDSELGMGTTIAVTVFQAVPFALAWVLGDSIRTRRA FT YFAQLEERATRLEKEREAQAKVAVAAERARIARELHDVVAHNVSVMVVQADGAAYVLDA FT APDQAKKALETISSTGRQALAEMRRLLGVLRTGEHKEAGEYVPQPDVEQIEDLVEQCRT FT SGLPVDFKIEGTPRQLPSGVELTAYRIVQEALTNTRKHGGENAGASVRLVYFDDGLGLL FT IEDDGKGAPHELYEEGGFDGQGHGLIGMRERIGMVGGTLDAGPRPGGGFRISALLPLKP FT AP" FT CDS 129653..130741 FT /transl_table=11 FT /gene="SCO3391" FT /gene_synonym="SCE126.09" FT /product="hypothetical protein" FT /note="SCE126.09, unknown,len: 362aa; similar to TR:O25492 FT (EMBL:AE000593) hypothetical protein from Helicobacter FT pylori (336 aa) fasta scores; opt: 143, z-score: 161.4, FT E(): 0.11, (31.5% identity in 111 aa overlap)." FT /db_xref="InterPro:IPR003788" FT /db_xref="UniProtKB/TrEMBL:Q9X852" FT /protein_id="CAB40931.1" FT /translation="MTPGTAGFRGAPEAHGTWRGWREATQEALYGPEGFYRAGPEGPAG FT HFRTSVHASPLFAGAVARLLCRVDEALGRPAVLDFVDMAAGRGELVAGVLAALPADVVA FT RTRAYAVEVAARPEGLDRRVQWLARPPDGVTGLLFANEWLDNVPVDVAEVDAEGVARRV FT LVRGDGAERLGEPVAGAEAEWLARWWPMPAEEGRRAEIGLPRDEAWASAVAALDAGLAV FT AADYAHSVSARPPFGTLTGFREGRETEPVPDGSCDITAHVALDACAAAHTARCTPEYAP FT PNALTRPQREILRALGVTGARPPLALASTDPAAYVRALASASQGAELTARGGLGDFRWL FT LQPVGPVDAEALLVDVADHEEQ" FT CDS complement(130706..131857) FT /transl_table=11 FT /gene="SCO3392" FT /gene_synonym="SCE126.10" FT /gene_synonym="nuoD2" FT /product="putative NADH dehydrogenase subunit NuoD2" FT /note="SCE126.10, nuoD2, probable NADH dehydrogenase FT subunit, len: 383 aa; similar to many others e.g. FT SW:NUOD_ECOLI NADH dehydrogenase chain D (407 aa) fasta FT scores; opt: 689, z-score: 821.3, E(): 0, (33.2% identity FT in 397 aa overlap). Contains two Pfam matches to entry FT PF00346 complex1_49Kd, Respiratory-chain NADH FT dehydrogenase, 49 Kd subunit and Prosite match to PS00535 FT Respiratory chain NADH dehydrogenase 49 Kd subunit FT signature." FT /db_xref="GOA:Q9X853" FT /db_xref="InterPro:IPR014029" FT /db_xref="UniProtKB/Swiss-Prot:Q9X853" FT /protein_id="CAB40932.1" FT /translation="MTPTTETTVGIGGAAESTDMVLNIGPQHPSTHGVLRLKLVLDGER FT ITSAEPVIGYMHRGAEKLFEARDYRQIIMLANRHDWLSAFSNELGVVLAVERMLGMEVP FT TRAVWTRTLLAELNRVLNHLMFLGSYPLELGGITPVFYAFREREVLQNVMEEVSGGRMH FT YMFNRVGGLKEDLPAGWTTRARGAVAAVRSRMDVFDDLVLGNEIFRGRTRGVGALSAEA FT VHAYGVSGPVARASGVDFDLRRDEPYLAYGELQDTLKVVTRTDGDCLARFECLLAQTHN FT ALDLADACLDRLAELAPGPVNQRLPKVLKAPEGHTYAWTENPLGINGYYLVSKGEKTPY FT RLKLRSASYNNIQALAELLPGTLVADMVAILGSLFFVVGDIDK" FT misc_feature complement(130709..130924) FT /note="Pfam match to entry PF00346 complex1_49Kd, FT Respiratory-chain NADH dehydrogenase, 49 Kd subunit, score FT 76.80, E-value 2e-27." FT misc_feature complement(131045..131461) FT /note="Pfam match to entry PF00346 complex1_49Kd, FT Respiratory-chain NADH dehydrogenase, 49 Kd subunit, score FT 112.40, E-value 3.2e-40." FT misc_feature complement(131657..131692) FT /note="PS00535 Respiratory chain NADH dehydrogenase 49 Kd FT subunit signature." FT CDS 131991..132446 FT /transl_table=11 FT /gene="SCO3393" FT /gene_synonym="SCE126.11" FT /product="putative integral membrane protein" FT /note="SCE126.11, possible integral membrane protein, len: FT 151aa; similar to other hypotheticals eg. TR:P96615 FT (EMBL:AB001488) hypothetical protein from Bacillus subtilis FT (159 aa) fasta scores; opt: 208, z-score: 264.3, E(): FT 2.1e-07, (30.3% identity in 145 aa overlap). Contains a FT possible membrane spanning hydrophobic region." FT /db_xref="InterPro:IPR005182" FT /db_xref="UniProtKB/TrEMBL:Q9X854" FT /protein_id="CAB40933.1" FT /translation="MWTGLPPGLLHLRRLLLVVWLGLLTVAAVVLPALFLDPLWAALAL FT LPLALTAWGWVMLGRNWRSWRYAERADDLLISRGVLWREETVVPYGRMQLVEVTSGPVE FT RHFGLASVQLHTAAAATDATIPGLDPAEAERLRDRLTELGEARSAGL" FT CDS 132443..134167 FT /transl_table=11 FT /gene="SCO3394" FT /gene_synonym="SCE9.01" FT /gene_synonym="SCE126.12" FT /product="hypothetical protein" FT /note="SCE9.01, hypothetical protein, partial CDS, len: FT >436 aa; unknown function, this is the remainder of CDS FT SCE126.12 (EMBL:AL049630). Weakly similar to TR:O33222 FT (EMBL:Z98260) Mycobacterium tuberculosis hypothetical FT protein (487 aa), fasta scores; opt: 203 z-score: 237.4 FT E(): 6.7e-06, 30.3% identity in 347 aa overlap. Contains FT hydrophobic membrane spanning region and contains probable FT coiled-coil from 394 to 429 (36 residues) (Max score: FT 1.471, probability 0.91)" FT /note="SCE126.12, partial CDS, unknown, proline-rich, len: FT >174aa;" FT /db_xref="InterPro:IPR005182" FT /db_xref="UniProtKB/TrEMBL:Q8CJW8" FT /protein_id="CAD55316.1" FT /translation="MTGPGTGRGAPEGGTAGRADGPAEYRGEPGPTALDRTRNDPPRKR FT RLDPAEPSDHTAAPAPETPNTAGTPANSASEPGLADPDRHEDSPPGTASHDDTAKPSDH FT AAAPAPEATGPDRDGPGTGTGTGAVGTLAKGDTASRGQGGEVVERRLHPVTPLRRAWAP FT VAVLVGWAVHDPDQAQRQLTRLTTTHLLIGLAVLIPAAALYGFLTWWFTHYAVTDTELR FT IRTGLLFRRTAHIRLERIQAIDVTQPLLARVAGVAKLKLDVIGTGKKDELAFLGADEAR FT ALRAELLARAAGFAPETAHEVGEAPARQLLRVPPGVLAVSLLLTGATWGTLLAAAVVPT FT LLWLATHNLWTVLATALPLVGAAGASSAGRFVGEYDWTVAESPDGLRIDHGLLDRAHET FT VPPGRVQTVRLVEPLLWRRRRWVRVELDVAGSSNSVLLPVAPREIAESVVARVLPGVSV FT PPGPELTRPPRRAARCRPLWWRGHGLAVTDAVFAARYGLLRRSLALVPHAKVQSVRLTQ FT GPWRRALRLADVHVDTGANKTVTARLRDAEEAAELLRSQAERSRTGRRDAPPDRWMA" FT CDS complement(134197..135372) FT /transl_table=11 FT /gene="SCO3395" FT /gene_synonym="SCE9.02c" FT /product="putative secreted protein" FT /note="SCE9.02c, putative secreted protein, len: 391 aa; FT unknown function, probable CDS suggested by positional base FT preference, GC frame analysis and amino acid composition. FT Hydrophobic region at N-terminus and degenerate FT E(T/A)(P/R)EQ repeat in centre. Contains probable FT coiled-coil from 45 to 114 (70 residues) (Max score: 1.834, FT probability 1.00). Contains possible N-terminal region FT signal peptide sequence" FT /db_xref="UniProtKB/TrEMBL:Q9X8H5" FT /protein_id="CAB42748.1" FT /translation="MILRVLAAAAAVTAVVGAVVMRHWDAQAGRQVADLTRARASDEWR FT FEERVAELESDLEESRELRQKLEHRLRAKRTELAGLRNEHASLLRRYATAETERASALE FT GRRLLEIEAAPQAPALPAARTAPAAETPGQETPVQEAREQEARGEETPGVDGAAEGVSG FT EGDAAAEEGSVPAVFSPEGSRLFLRANAALARFGGDAPADPDGGDRAAASEAPDGSGGD FT DDGDGGGEGAPATEAGPEDEAQGQPEAADGHERTAAASPTTTSDERPAQPTQSTQPTRR FT ADGHFTVPTAVAVVPAAPARRPVVEGGFDFFGTKPADNAAGASDAALETVQNEDLADVV FT GQEALALHKAEAEVSFKPAGEESRGVGQVIDLTAHDETEQIDVQGLRSAVS" FT repeat_region complement(134927..134955) FT /note="2x degenerate 15 bp direct repeats" FT repeat_region complement(134956..134986) FT /note="2x degenerate 15 bp direct repeats" FT CDS complement(135623..136756) FT /transl_table=11 FT /gene="SCO3396" FT /gene_synonym="SCE9.03c" FT /product="putative membrane protein" FT /note="SCE9.03c, possible membrane protein, len: 370 aa; FT unknown function, similar to SW:YLI2_CORGL (EMBL:X60312) FT Corynebacterium glutamicum hypothetical protein (426 aa), FT fasta scores; opt: 274 z-score: 307.1 E(): 8.8e-10, 23.9% FT identity in 351 aa overlap and TR:P94973 (EMBL:Z85982) FT Mycobacterium tuberculosis hypothetical protein (489 aa) FT (23.1% identity in 386 aa overlap). Contains hydrophobic FT regions at N-terminus, possibly a membrane anchor" FT /db_xref="InterPro:IPR000801" FT /db_xref="UniProtKB/TrEMBL:Q9X8H6" FT /protein_id="CAB42749.1" FT /translation="MGLTSNKVLALAVVAGVLLFAGTVWWWPRLAGRSVRAVLGRAGLL FT LATQVAVFAAVGLVANQSFGFYGSWADLFGREDGQGVVVDHSAGAGGGPLRVVGDRRVA FT PAGGARPDVSGRVEEIRVVGRTSRIASPAYVYLPPEYFQTRHRGRTFPAAVVLTGYPGT FT AEALVEKLHYPRTALELAKAGRMRPMILVMLRPTVAPPRDTECVDVPGGPQTETFFAKD FT LPQAVSTHYRVAKGPRSWGVVGNSTGGYCALKLAAHHPEVYAAGAGLSPYYDAPNDPTT FT GDLFQGDEGLEKRASLWWCLKNAPAPDTSLLVTSSRTGETNYKDTLKFIDLVKGKRPTR FT ISSIILESGGHNFNTWRREIPATLRWLDERLDGGRDA" FT RBS 136913..136916 FT /note="possible RBS" FT CDS 136919..138724 FT /transl_table=11 FT /gene="SCO3397" FT /gene_synonym="SCE9.04" FT /product="putative integral membrane lysyl-tRNA synthetase" FT /note="SCE9.04, possible integral membrane lysyl-tRNA FT synthetase, len: 601 aa; unknown function, similar to FT hypothetical proteins e.g. N-terminal half of SW:P94974 FT (SYK2_MYCTU) Mycobacterium tuberculosis probable lysyl-tRNA FT synthetase (1172 aa), fasta scores; opt: 1245 z-score: FT 1445.4 E(): 0, 39.9% identity in 604 aa overlap and FT TR:O69916 (EMBL:AL023861) S.coelicolor putative integral FT membrane protein (589 aa) (45.8% identity in 539 aa FT overlap). Contains hydrophobic, possible membrane-spanning FT regions" FT /db_xref="GOA:Q9X8H7" FT /db_xref="InterPro:IPR007426" FT /db_xref="UniProtKB/TrEMBL:Q9X8H7" FT /protein_id="CAB42750.1" FT /translation="MSGEVPTRPTRIRRALRGPRPDRIPLLVGRACVLVGLLDIAAGSF FT PRFRHSRMHALAEVLPGAFGPFAAALSLSAGVLLLLLAHGLKRRKRRAWRAAAALLPLG FT AVAQFTYRHSLLGVLISVALLFPLLRHRDEFAALPDPRSRWRALANFVLMSAGSVLLGL FT LVVNAHPHRMLGDPSLADRITHVLYGLFGVEGPVDYRGNTSWTVAFSLGALGLLTAVTT FT IYLAFRPEHPAARLTEDDEIRLRALLARHGGRDSLGHFALRRDKAVVFSPSGKAAVTYR FT VVSGVMLASGDPIGDVEAWPGAIERFMDEARAHSWTPAVMGCSETGGEVWTRETGLDAL FT ELGDEAVVDVADFSLAGRAMRNVRQMVKRIERAGYETRVRRVADLSDAELDRVRRAADA FT WRGTDTERGFSMALGRVGDPADGDCLIATAHKQDTEPGEYGDLKAVLHFVPWGTDGASL FT DLMRRDRAADPGMNELLIVAALQAAPKLGIARVSLNFAMFRAALARGEKIGAGPVLRAW FT RGLLVFLSRWFQIESLYKFNAKFRPRWEPRFVVYRRSADLPRIGFAAMQAEGFVTIPLP FT RFLQRRTPSRRPCAHGVPEREARAA" FT CDS 139193..140059 FT /transl_table=11 FT /gene="SCO3398" FT /gene_synonym="SCE9.05" FT /gene_synonym="folP" FT /product="putative dihydropteroate synthase" FT /note="SCE9.05, folP, probable dihydropteroate synthase, FT len: 288 aa; similar to many e.g. SW:DHPS_ECOLI FT (EMBL:X68776), FolP, Escherichia coli dihydropteroate FT synthase (282 aa), fasta scores; opt: 618 z-score: 694.3 FT E(): 2.4e-31, 39.9% identity in 268 aa overlap. Contains FT Pfam match to entry PF00809 DHPS, Dihydropteroate synthase, FT score 418.00, E-value 8.9e-122, PS00792 Dihydropteroate FT synthase signature 1 and PS00793 Dihydropteroate synthase FT signature 2" FT /db_xref="GOA:Q9X8H8" FT /db_xref="HSSP:1EYE" FT /db_xref="InterPro:IPR001969" FT /db_xref="UniProtKB/TrEMBL:Q9X8H8" FT /protein_id="CAB42751.1" FT /translation="MSKQTGRRRRHLAGLTAWDRCAVMGVVNVTPDSFSDGGRFFDTTA FT AIKHGLDLVAQGADLVDVGGESTRPGATRVDEDEELRRVVPVVRGLASEGVTVSVDTMR FT ASVAGQALAAGATLVNDVSGGLADPRMIPVVADTGAPFVVMHWRGLLKDGNVKGTYADV FT VTEVVDELHARVDAVLDGGIAPDRVIVDPGLGFSKDAEHDLVLLAHLDRLLTLGHPLLV FT AASRKRFLGRVLAGPDAAPPPARERDAATAAVSALAAQAGAWAVRVHEVRATADAVRVA FT RAVEGAR" FT misc_feature 139259..139306 FT /note="PS00792 Dihydropteroate synthase signature 1" FT misc_feature 139262..140041 FT /note="Pfam match to entry PF00809 DHPS, Dihydropteroate FT synthase, score 418.00, E-value 8.9e-122" FT misc_feature 139361..139402 FT /note="PS00793 Dihydropteroate synthase signature 2" FT CDS 140056..140559 FT /transl_table=11 FT /gene="SCO3399" FT /gene_synonym="SCE9.06" FT /product="hypothetical protein" FT /note="SCE9.06, hypothetical protein, len: 167 aa; probable FT CDS suggested by positional base preference, GC frame FT analysis and amino acid composition" FT /db_xref="UniProtKB/TrEMBL:Q9X8H9" FT /protein_id="CAB42752.1" FT /translation="MNAPHLDVEQVEAANTAFYEALEEGDFEKVSEFWLTPSDLGVDES FT YHDPADAGVVSCVHPGWPVLTGRGEVLRSYALIMANTDYIQFFLTDVHVSVTGDTALVT FT CTENILSGGPAPDGGEELGPLVGQLVVATNTFRRTPAGWKLWSHHASPVLAETEDEDGE FT DTPP" FT RBS 140851..140855 FT /note="possible RBS" FT CDS 140864..141223 FT /transl_table=11 FT /gene="SCO3400" FT /gene_synonym="SCE9.07" FT /gene_synonym="folB" FT /product="putative dihydroneopterin aldolase" FT /note="SCE9.07, folB, probable dihydroneopterin aldolase, FT len: 119 aa; similar to many e.g. the N-terminal, FT dihydroneopterin aldolase domain of SW:SULD_STRPN FT (EMBL:U16156), sulD, Streptococcus pneumoniae bifunctional FT dihydroneopterin aldolase/hydroxymethyldihydropterin FT pyrophosphokinase (270 aa), fasta scores; opt: 240 z-score: FT 310.8 E(): 5.5e-10, 31.9% identity in 119 aa overlap. FT Putative start codon suggested by GC frame plot and the FT presence of a potential RBS" FT /db_xref="GOA:Q9X8I0" FT /db_xref="HSSP:1DHN" FT /db_xref="InterPro:IPR006156" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8I0" FT /protein_id="CAB42753.1" FT /translation="MDRVALRGLKARGHHGVFPKEREDGQTFLVDIVLGLDTRPAAADD FT DLAKTVHYGIVAEEVVAVVEGEPVNLVETLAERIAQVCLKHEGVEEVEVCVHKPDAPIT FT VPFDDVTVTIIRSRV" FT RBS 141210..141213 FT /note="possible RBS" FT CDS 141220..141831 FT /transl_table=11 FT /gene="SCO3401" FT /gene_synonym="SCE9.08" FT /gene_synonym="folK" FT /product="putative hydroxymethyldihydropteridine FT pyrophosphokinase" FT /note="SCE9.08, folK, probable FT hydroxymethyldihydropteridine pyrophosphokinase, len: 203 FT aa; similar to many e.g. SW:HPPK_ECOLI (EMBL:L06495), FolK, FT Escherichia coli FT 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine FT pyrophosphokinase (158 aa), fasta scores; opt: 351 z-score: FT 426.9 E(): 1.9e-16, 42.0% identity in 138 aa overlap. FT Putative start codon suggested by GC frame plot and the FT presence of a potential RBS, resulting in a short FT N-terminal extension not present in homologs. There is an FT alternative start codon at position 17. Contains Pfam match FT to entry PF01288 HPPK, FT 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK), FT score 145.80, E-value 7.5e-40" FT /db_xref="GOA:Q9X8I1" FT /db_xref="HSSP:1F9Y" FT /db_xref="InterPro:IPR000550" FT /db_xref="UniProtKB/TrEMBL:Q9X8I1" FT /protein_id="CAB42754.1" FT /translation="MSAPFAQGPSDPTVQPVPASVIEQVDAADTTLSNPKRAVVALGAN FT LGNRLETLQGAIDALEDTPGVRVKGVSPVYETEPWGVAPDSQPSYFNAVVILKTTLPPS FT SLLERAHAVEEAFHRVRDERWGPRTLDVDIVAYAEVVSDDPHLTLPHPRAHERAFVLAP FT WLDVDPEAALPGRGRVADLLAAVTRDGVAPRADLELQLPE" FT misc_feature 141322..141783 FT /note="Pfam match to entry PF01288 HPPK, FT 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK), FT score 145.80, E-value 7.5e-40" FT CDS 141902..142390 FT /transl_table=11 FT /gene="SCO3402" FT /gene_synonym="SCE9.09" FT /product="possible secreted protein" FT /note="SCE9.09, possible secreted protein, len: 162 aa; FT unknown function, similar to TR:O06277 (EMBL:Z95557) FT Mycobacterium tuberculosis hypothetical protein (158 aa), FT fasta scores; opt: 174 z-score: 218.1 E(): 7.9e-05, 31.3% FT identity in 128 aa overlap. Hydrophobic protein containing FT possible N-terminal signal sequence" FT /db_xref="UniProtKB/TrEMBL:Q9X8I2" FT /protein_id="CAB42755.1" FT /translation="MKELRIRVLAGVFVVAGILSWAGARLWNSVGTLPSVPLAAPVVLA FT LIAVILLATALSIRARLRAQRDRVPDAKGVDPMMAARAVVFGQASALVAALVAGMYGGT FT GVFLLEYLDIPARRDQAIYAGASVVAGIAVIAAALFMERVCRLPEDEDDDHPGAASAA" FT CDS complement(142406..143011) FT /transl_table=11 FT /gene="SCO3403" FT /gene_synonym="SCE9.10c" FT /gene_synonym="folE" FT /product="putative GTP cyclohydrolase I" FT /note="SCE9.10c, folE, probable GTP cyclohydrolase I, len: FT 201 aa; similar to many e.g. SW:GCH1_BACSU (EMBL:M37320), FT MtrA, Bacillus subtilis GTP cyclohydrolase I (190 aa), FT fasta scores; opt: 728 z-score: 880.0 E(): 0, 58.9% FT identity in 185 aa overlap. Contains Pfam match to entry FT PF01227 GTP_cyclohydroI, GTP cyclohydrolase I, score FT 351.80, E-value 7.2e-102, PS00859 GTP cyclohydrolase I FT signature 1 and PS00860 GTP cyclohydrolase I signature 2" FT /db_xref="GOA:Q9X8I3" FT /db_xref="HSSP:1IS8" FT /db_xref="InterPro:IPR018234" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8I3" FT /protein_id="CAB42756.1" FT /translation="MTDPVTLDGEGQIGEFDEKRAENAVRELLIAVGEDPDREGLRETP FT ARVARAYREIFAGLWQEPEDVLTTTFDLGHDEMVLVKDIEVFSTCEHHLVPFRGVAHVG FT YIPSTSGKITGLSKLARLVDVYARRPQVQERLTTQIADSLMEILEPRGVIVVVECEHMC FT MSMRGIRKPGAKTLTSAVRGQLRDVATRNEAMSLIMAR" FT misc_feature complement(142412..142957) FT /note="Pfam match to entry PF01227 GTP_cyclohydroI, GTP FT cyclohydrolase I, score 351.80, E-value 7.2e-102" FT misc_feature complement(142601..142633) FT /note="PS00860 GTP cyclohydrolase I signature 2" FT misc_feature complement(142733..142783) FT /note="PS00859 GTP cyclohydrolase I signature 1" FT CDS complement(143143..145149) FT /transl_table=11 FT /gene="SCO3404" FT /gene_synonym="SCE9.11c" FT /gene_synonym="ftsH2" FT /product="cell division protein ftsH homolog" FT /note="SCE9.11c, ftsH2, cell division protein ftsH homolog, FT len: 668 aa; similar to many e.g. SW:FTSH_ECOLI FT (EMBL:M83138), ftsH, Escherichia coli membrane-bound, FT ATP-dependent protease involved in cell cycle control (644 FT aa), fasta scores; opt: 1921 z-score: 1987.4 E(): 0, 48.5% FT identity in 641 aa overlap. Similar to TR:O69875 FT (EMBL:AL023797), ftsH, S.coelicolor cell division protein FT ftsH homolog (648 aa) (43.3% identity in 610 aa overlap), FT but lacking the proline-rich N-terminus. Contains a FT hydrophobic, possible membrane-spanning region near the FT N-terminus. Contains Pfam match to entry PF00004 AAA, FT ATPases associated with various cellular activities (AAA), FT score 335.00, E-value 8.4e-97, PS00674 AAA-protein family FT signature and PS00017 ATP/GTP-binding site motif A FT (P-loop)" FT /db_xref="GOA:Q9X8I4" FT /db_xref="HSSP:1IY1" FT /db_xref="InterPro:IPR003960" FT /db_xref="UniProtKB/TrEMBL:Q9X8I4" FT /protein_id="CAB42757.1" FT /translation="MWIVLAVLAVVVLMQVVGSSGGYKTVDTGQVVQAINDNRVESAKL FT TTGDEQTIKVQLKDGQKVEGSSKIQASYIGDQGVTLANTLQNKYQDKQIPDGYTVSPSK FT QNPFVGILLSLLPFVLIVVVFLFLMNQMQGGGSRVMNFGKSKAKLITKDTPKTTFSDVA FT GSDEAVEELHEIKEFLQEPAKFQAVGAKIPKGVLLYGPPGTGKTLLARAVAGEAGVPFY FT SISGSDFVEMFVGVGASRVRDLFEQAKANAPAIVFVDEIDAVGRHRGAGLGGGHDEREQ FT TLNQLLVEMDGFDVKGGVILIAATNRPDILDPALLRPGRFDRQIAVDRPDMQGRLEILK FT VHQKGKPVAPDVDLSAVARRTPGMTGADLANVLNEAALLTARSDQKLIDNHMLDEAIDR FT VVAGPQKRTRIMSDKEKKITAYHEGGHALVAAASPNSDPVHKITILSRGRALGYTMVLP FT DEDKYSTTRNEMLDQLAYMLGGRAAEELVFHDPTTGAANDIEKATGLARAMVTQYGMTE FT RLGAIKFGGDNSEPFLGREMAHQRDYSEEVAALVDEEVKKLIETAHNEAWEILVENRDV FT LDNLVLALLEKETLGKEEIAEVFSQIVKRPARPAWTGSSRRTPSTRPPVLSPKELALTN FT GANGATAAISTAKSTTVEPAPAPERAPEDRPES" FT misc_feature complement(144004..144567) FT /note="Pfam match to entry PF00004 AAA, ATPases associated FT with various cellular activities (AAA), score 335.00, FT E-value 8.4e-97" FT misc_feature complement(144199..144255) FT /note="PS00674 AAA-protein family signature" FT misc_feature complement(144529..144552) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(145379..145942) FT /transl_table=11 FT /gene="SCO3405" FT /gene_synonym="SCE9.12c" FT /gene_synonym="hprT" FT /product="putative hypoxanthine phosphoribosyltransferase" FT /note="SCE9.12c, hprT, probable hypoxanthine FT phosphoribosyltransferase, len: 187 aa; similar to many FT e.g. TR:O33799 (EMBL:AF008931), HprT, Salmonella FT typhimurium hypoxanthine phosphoribosyltransferase (178 FT aa), fasta scores; opt: 583 z-score: 711.2 E(): 2.7e-32, FT 54.2% identity in 166 aa overlap. The start codon is FT uncertain as there are 5 potential. Contains Pfam match to FT entry PF00156 Pribosyltran, Purine/pyrimidine FT phosphoribosyl transferases, score 177.70, E-value 1.9e-49 FT and PS00103 Purine/pyrimidine phosphoribosyl transferases FT signature. Contains probable coiled-coil from 3 to 39 (37 FT residues) (Max score: 1.481, probability 0.93)" FT /db_xref="GOA:Q9X8I5" FT /db_xref="HSSP:1J7J" FT /db_xref="InterPro:IPR002375" FT /db_xref="UniProtKB/TrEMBL:Q9X8I5" FT /protein_id="CAB42758.1" FT /translation="MMRVDANDMGADLEKVLITKEEIDAKLAELAAKIDAEYAGKDLLI FT VGVLKGAVMVMADLARTLSTPVTMDWMAVSSYGAGTQSSGVVRILKDLDTDIKGRHVLI FT VEDIIDSGLTLSWLISNLGSREPASLKVCTLLRKPDAAKVAIDVEWVGFDIPNEFVVGY FT GLDYAEKYRNLPFVGTLAPHVYGG" FT misc_feature complement(145382..145918) FT /note="Pfam match to entry PF00156 Pribosyltran, FT Purine/pyrimidine phosphoribosyl transferases, score FT 177.70, E-value 1.9e-49" FT misc_feature complement(145601..145639) FT /note="PS00103 Purine/pyrimidine phosphoribosyl FT transferases signature" FT CDS complement(146014..147072) FT /transl_table=11 FT /gene="SCO3406" FT /gene_synonym="SCE9.13c" FT /product="conserved hypothetical protein" FT /note="SCE9.13c, conserved hypothetical protein, len: 352 FT aa; similar to many e.g. SW:MESJ_ECOLI (EMBL:D49445), mesJ, FT Escherichia coli cell cycle protein (432 aa), fasta scores; FT opt: 327 z-score: 356.8 E(): 1.5e-12, 34.4% identity in 282 FT aa overlap. Highly similar to SW:YZC5_MYCTU (EMBL:Z95436) FT Mycobacterium tuberculosis hypothetical protein (323 aa) FT (47.9% identity in 305 aa overlap)" FT /db_xref="GOA:Q9X8I6" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8I6" FT /protein_id="CAB42759.1" FT /translation="MGPHPAVAAIRLAVRRVLHDILTELNTPAGVPAATAVERTPERAP FT GLPTAPLVLVACSGGADSMALASALAFEAPRLGVRAGGVTVDHGLQSGSDLRAEEVVLR FT LRELGLDPVEATAVTVGRAGGPEAAARDARYAALDAAAARHGAAAVLLGHTRDDQAETV FT LLGLARGSGIRSLSGMAAVSGAGGRYRRPFLQVDRQTARKACMVQSLPVWDDPHNADPA FT YTRSRLRHEGLPALEKALGKGVVEALARTAQLSRDDADALDTWARQAEAGVRDATGGLE FT CAKLYALPPAVRRRILRRAALEAGAPGGALFARHIEEVDRLITGWRGQGAINLPGKVVA FT RRQGGRLVIRQG" FT CDS complement(147265..148392) FT /transl_table=11 FT /gene="SCO3407" FT /gene_synonym="SCE9.14c" FT /product="conserved hypothetical protein" FT /note="SCE9.14c, conserved hypothetical protein, len: 375 FT aa; unknown function, highly similar to TR:O06381 FT (EMBL:Z95436) Mycobacterium tuberculosis hypothetical FT protein (350 aa), fasta scores; opt: 720 z-score: 820.9 FT E(): 0, 41.6% identity in 361 aa overlap and similar to FT TR:O53341 (EMBL:AL021646) Mycobacterium tuberculosis FT hypothetical protein (472 aa) (25.6% identity in 383 aa FT overlap) and TR:Q49746 (EMBL:U00016) Mycobacterium leprae FT hypothetical protein (479 aa) (24.9% identity in 305 aa FT overlap)" FT /db_xref="InterPro:IPR018766" FT /db_xref="UniProtKB/TrEMBL:Q9X8I7" FT /protein_id="CAB42760.1" FT /translation="MTSIGANSGMVDWNLAVATATRLVRPGPEVSRDEARAVVAELRRH FT AKSSEEHVRGFTRMGTEETHDTPLLVVDRPGWVRANVAGFRELLKPLLEKMQERRGGGA FT GNAVLGAVGGKVTGVELGMLLSFLSSRVLGQYETFAPATRELPAGANGGGRLLLVAPNI FT VHVERELDVEPHDFRLWVTLHEETHRTQFTAVPWLRDHLEGEIQSFLAETDVDPMTVLE FT RVREAAQSLAGGRPEAEEDDGGRSLVELVQTPAQREVLGRLTAVMSLLEGHADFVMDGV FT GPAVVPSVGEIREKFQQRRAKGASRLDMALRKLLGLDAKLRQYRDGERFVRAVVEECGM FT DGFNRVWTSPNTLPTKSEIAKPADWIARVHRKPEA" FT CDS complement(148514..149893) FT /transl_table=11 FT /gene="SCO3408" FT /gene_synonym="SCE9.15c" FT /product="conserved hypothetical protein" FT /note="SCE9.15c, possible penicillin-binding protein, len: FT 459 aa; weakly similar to penicillin-binding proteins e.g. FT SW:DAC_ACTSP (EMBL:X64790), dac, Actinomadura sp. FT D-alanyl-D-alanine carboxypeptidase precursor (538 aa), FT fasta scores; opt: 248 z-score: 243.2 E(): 3.2e-06, 29.5% FT identity in 499 aa overlap and TR:O85665 (EMBL:AF071224), FT pbp3, Neisseria gonorrhoeae penicillin binding protein 3 FT (469 aa) (26.8% identity in 399 aa overlap). Similar to FT SC9B2.18c (EMBL:AL035212) S.coelicolor probable FT carboxypeptidase (451 aa) (36.1% identity in 429 aa FT overlap). The start codon is uncertain as there are 2 FT potential" FT /db_xref="GOA:Q9X8I8" FT /db_xref="InterPro:IPR000667" FT /db_xref="UniProtKB/TrEMBL:Q9X8I8" FT /protein_id="CAB42761.1" FT /translation="MVTVAGPWDSTGQRTAERDRAVALGRPGGTDHGRGSGASGTSSGS FT PRPAPSAGAVLAGLDGTSAPGGIKAAPGDQDLADLLDPLLKDAPGLGGRRAAAVVDLTT FT GKRLYGLGSDAPLTPASTTKIATAVAALTALGPDHRLTTRTALEADTGEVVLVGGGDPT FT LTAREDARGLASLRTLAGKTAAALKKRGVREVTLSYDTTLYAGTEMHPIGVNENLARVT FT ALMADEGRTDDSTSGPAPRVPDPAADAARTFAGLLKQHGVTASAPGPSKATGRADTLAT FT VSSPPLAALVERMLTNSDNDLAEALARHTAVATGKPADFDGAGAAVTARLKQLGLPVGG FT ARFHDGSGLDRTDLISPDLLTALLAEAADPARPQLRPVLTGLPVAHFTGTLAGRYTDGA FT AGLVRAKTGTLTGVNTLAGTVTTPDGRLLGFAFLANDTTDAWAAQSALDGAATTLASET FT P" FT RBS 150182..150186 FT /note="possible RBS" FT CDS 150195..150686 FT /transl_table=11 FT /gene="SCO3409" FT /gene_synonym="SCE9.16" FT /gene_synonym="ppa" FT /product="putative inorganic pyrophosphatase" FT /note="SCE9.16, ppa, probable inorganic pyrophosphatase, FT len: 163 aa; similar to many e.g. SW:IPYR_SULAC FT (EMBL:X81842), ppa, Sulfolobus acidocaldarius inorganic FT pyrophosphatase (173 aa), fasta scores; opt: 483 z-score: FT 617.4 E(): 4.6e-27, 46.4% identity in 166 aa overlap. FT Contains Pfam match to entry PF00719 Pyrophosphatase, FT Inorganic pyrophosphatase, score 163.70, E-value 3e-45 and FT PS00387 Inorganic pyrophosphatase signature" FT /db_xref="GOA:Q9X8I9" FT /db_xref="HSSP:1QEZ" FT /db_xref="InterPro:IPR008162" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8I9" FT /protein_id="CAB42762.1" FT /translation="MEFDVTIEIPKGSRNKYEVDHETGRIRLDRRLFTSTAYPTDYGFV FT ENTLGEDGDPLDALVILDEPTFPGCLIRCRAIGMFRMTDEAGGDDKLLCVPSTDPRVEH FT LRDIHHVSEFDRLEIQHFFEVYKDLEPGKSVEGADWVGRTEAEAEIERSYKRFKDQGGH FT " FT misc_feature 150204..150671 FT /note="Pfam match to entry PF00719 Pyrophosphatase, FT Inorganic pyrophosphatase, score 163.70, E-value 3e-45" FT misc_feature 150348..150368 FT /note="PS00387 Inorganic pyrophosphatase signature" FT CDS 150773..152509 FT /transl_table=11 FT /gene="SCO3410" FT /gene_synonym="SCE9.17" FT /product="putative membrane protein" FT /note="SCE9.17, possible membrane protein, len: 578 aa; FT similar to TR:O69704 (EMBL:AL022121) Mycobacterium FT tuberculosis putative membrane protein (529 aa), fasta FT scores; opt: 642 z-score: 677.3 E(): 2.1e-30, 31.6% FT identity in 481 aa overlap. The start codon is uncertain as FT there are 2 potential. The general position of the CDS FT start was estimated by GC frame plot. Contains hydrophobic, FT possible membrane-spanning regions in the C-terminal half, FT while the N-terminal half is more hydrophilic" FT /db_xref="InterPro:IPR010619" FT /db_xref="UniProtKB/TrEMBL:Q9X8J0" FT /protein_id="CAB42763.1" FT /translation="MSVPGSVAQVTEAEEPKPQSDEARSAFRQPSGIAASIDGESSTTS FT EFEIPQGFAVPRHAGTESETTSEFSLPDGLEVPQAPPADTEGSAFTMPSTHSAWTAPTA FT FTPASGFPAVSLTDVPWQDRMRAMLRMPVAERPAPEPSQKHDDETGPAVPRVLDLTLRI FT GELLLAGGEGAEDVEAAMFAVCRSYGLDRCEPNVTFTLLSISYQPSLVEDPVTASRTVR FT RRGTDYTRLAAVFHLVDDLSDPDTNISLEEAYRRLAEIRRNRHPYPTWVLTVASGLLAG FT GASLLVGGGLTVFFAAMFGSMLGDRLAWLCAGRGLPEFYQFAVAAMPPAAMGVVLTVTH FT VDVKASAVITGGLFALLPGRALVAGVQDGLTGFYITAAARLLEVMYFFVSIVAGVLVVL FT YFGVQLGAELNPDAKLGTGDEPFVQIFASMLLSLAFAILLQQERATVLAVTLNGGIAWC FT VYGAMNYAGDISPVASTAAAAGLVGLFGQLMSRYRFASALPYTTAAIGPLLPGSATYFG FT LLGIAQGEVDSGLLSLSNAVALAMAIAIGVNLGGEISRLFLKVPGAASAAGRRAAKRTR FT GF" FT CDS complement(152506..153417) FT /transl_table=11 FT /gene="SCO3411" FT /gene_synonym="SCE9.18c" FT /product="possible membrane protein" FT /note="SCE9.18c, possible membrane protein, len: 303 aa; FT similar to many hypothetical proteins e.g. SW:DEDA_ECOLI FT (EMBL:M68934), dedA, Escherichia coli hypothetical protein FT in hisT-purF region (219 aa), fasta scores; opt: 588 FT z-score: 585.6 E(): 2.7e-25, 49.7% identity in 187 aa FT overlap. Similar to others from S.coelicolor e.g. TR:O86627 FT (EMBL:AL031155) DedA family hypothetical protein (228 aa) FT (41.4% identity in 203 aa overlap). Central region contains FT hydrophobic, possible membrane spans and C-terminal region FT contains glutamine-rich repeats. Contains Pfam match to FT entry PF00597 DedA, DedA family, score 104.00, E-value FT 2.9e-27" FT /db_xref="InterPro:IPR015414" FT /db_xref="UniProtKB/TrEMBL:Q9X8J1" FT /protein_id="CAB42764.1" FT /translation="MTTLALGPEWISPDYLIETFSLPGILLIVFAESGLFAFLPGDSLL FT FTAGLFVAQGEYISQPLWLVCTLIVAAAVLGDQVGYMIGKFFGPKLFSRPNSKLFKQEN FT LEKAHEFMEKYGPKAIVLARFVPIVRTFAPIVAGAGRMKYRTFLTYNVIGGVAWGTGVT FT LAGYWLGQIEFIRAHVEGILVLIILVSVVPIAIEYLRERKKKQRAAAAGPTPPAAQQHQ FT PQPPYPVMDDATTQLRRVDPYDQPQQQHDQQYDPGYGNQSYGNQPYGGQQPPQQPYAQQ FT YPQGYGDQPQQYGDQYPYNQGR" FT repeat_region complement(152548..152598) FT /note="imperfect 51 bp direct repeat" FT repeat_region complement(152632..152682) FT /note="imperfect 51 bp direct repeat" FT misc_feature complement(152860..153351) FT /note="Pfam match to entry PF00597 DedA, DedA family, score FT 104.00, E-value 2.9e-27" FT CDS 153598..153918 FT /transl_table=11 FT /gene="SCO3412" FT /gene_synonym="SCE9.19" FT /product="conserved hypothetical protein" FT /note="SCE9.19, conserved hypothetical protein, len: 106 FT aa; unknown function, weakly similar to e.g. TR:O26644 FT (EMBL:AE000837) Methanobacterium thermoautotrophicum FT hypothetical protein (127 aa), fasta scores; opt: 338 FT z-score: 369.7 E(): 2.9e-13, 50.5% identity in 107 aa FT overlap" FT /db_xref="InterPro:IPR002765" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8J2" FT /protein_id="CAB42765.1" FT /translation="MLVVTTNDLPGHRVQEVLGEVFGLTVRSRHLGSQIGAGLKSLVGG FT ELRGLTKTLVETRNQAMERLVEQARARGANAVLSFRFDVTEAADVGTEVCAYGTAVVVA FT RE" FT CDS complement(153964..154725) FT /transl_table=11 FT /gene="SCO3413" FT /gene_synonym="SCE9.20" FT /gene_synonym="tipA" FT /product="transcriptional regulator" FT /note="SCE9.20c, tipA, transcriptional regulator, len: 253 FT aa; highly similar to many e.g. SW:TIPA_STRLI FT (EMBL:S64314), TipA, Streptomyces lividans FT thiostrepton-binding transcriptional activator (253 aa), FT fasta scores; opt: 1693 z-score: 1909.7 E(): 0, 99.6% FT identity in 253 aa overlap. Weakly similar to others from FT S. coelicolor e.g. TR:O54191 (EMBL:AL021411) probable FT transcriptional regulator (196 aa) (29.8% identity in 181 FT aa overlap). Contains Pfam match to entry PF00376 merR, FT Bacterial regulatory proteins, merR family, score 66.50, FT E-value 5.7e-1 and PS00552 Bacterial regulatory proteins, FT merR family signature. Contains probable coiled-coil from FT 77 to 107 (31 residues) (Max score: 1.523, probability FT 0.97)" FT /db_xref="GOA:P0A4T8" FT /db_xref="InterPro:IPR000551" FT /db_xref="UniProtKB/Swiss-Prot:P0A4T8" FT /protein_id="CAB42766.1" FT /translation="MSYSVGQVAGFAGVTVRTLHHYDDIGLLVPSERSHAGHRRYSDAD FT LDRLQQILFYRELGFPLDEVAALLDDPAADPRAHLRRQHELLSARIGKLQKMAAAVEQA FT MEARSMGINLTPEEKFEVFGDFDPDQYEEEVRERWGNTDAYRQSKEKTASYTKEDWQRI FT QDEADELTRRFVALMDAGEPADSEGAMDAAEDHRQGIARNHYDCGYEMHTCLGEMYVSD FT ERFTRNIDAAKPGLAAYMRDAILANAVRHTP" FT misc_feature complement(154603..154710) FT /note="Pfam match to entry PF00376 merR, Bacterial FT regulatory proteins, merR family, score 66.50, E-value FT 5.7e-16" FT misc_feature complement(154642..154710) FT /note="PS00552 Bacterial regulatory proteins, merR family FT signature" FT CDS complement(154835..155281) FT /transl_table=11 FT /gene="SCO3414" FT /gene_synonym="SCE9.21c" FT /product="putative transcriptional regulator" FT /note="SCE9.21c, possible transcriptional regulator, len: FT 148 aa; weakly similar to TR:P71885 (EMBL:Z79702) FT Mycobacterium tuberculosis hypothetical protein (163 aa), FT fasta scores; opt: 166 z-score: 220.3 E(): 6e-05, 29.5% FT identity in 139 aa overlap and TR:O34949 (EMBL:AJ002571), FT ykoM, Bacillus subtilis hypothetical protein (154 aa) FT (27.0% identity in 141 aa overlap). Contains Pfam match to FT entry PF01047 MarR, MarR family, score 71.50, E-value FT 1.8e-17" FT /db_xref="GOA:Q9X8J3" FT /db_xref="InterPro:IPR000835" FT /db_xref="UniProtKB/TrEMBL:Q9X8J3" FT /protein_id="CAB42767.1" FT /translation="MSHVTPAFVDLVRVETRLYNAVSSRLRDEQGVSLGQFEFLEIIDR FT VPGCRVLDIVGELAITVGAVSKAVDRLVAAGWCVRAVNPQDRRSSVLRLTSEGDRRLAA FT CRPVVESALASLTEVVPPDDLHRIASALAVLRAHLEAGSHGRPG" FT misc_feature complement(154877..155188) FT /note="Pfam match to entry PF01047 MarR, MarR family, score FT 71.50, E-value 1.8e-17" FT CDS 155518..156318 FT /transl_table=11 FT /gene="SCO3415" FT /gene_synonym="SCE9.22" FT /product="putative esterase" FT /note="SCE9.22, probable esterase, len: 266 aa; similar to FT many e.g. SW:BAH_STRHY (EMBL:M64783), bah, Streptomyces FT hygroscopicus acetyl-hydrolase in bialaphos biosynthetic FT gene cluster (299 aa), fasta scores; opt: 637 z-score: FT 678.5 E(): 1.8e-30, 45.3% identity in 236 aa overlap. FT Contains PS01173 Lipolytic enzymes 'G-D-X-G' family, FT putative histidine active site" FT /db_xref="GOA:Q9X8J4" FT /db_xref="HSSP:1LZL" FT /db_xref="InterPro:IPR013094" FT /db_xref="UniProtKB/TrEMBL:Q9X8J4" FT /protein_id="CAB42768.1" FT /translation="MVSRRTVLGGRPALELAPDTASGPGRLLYLHGGGYLAGSPDTHAG FT LAGELARRAGLRAVSVDYRLAPEHPFPAAVDDGLAAYRELLSTGTDPQDLVLAGDSAGG FT GLGIATLLAAREAGLPQPAAVALFSPWVDLTLTGGSIRSKEGADPIFTEADVRAYADLY FT VGAGDRAAPLASPVFADLAGLPPLLVQAGANEVLLDDAVRLAGRAGADDVEVTLEVGPG FT LPHVYQLHYGRLEEADAALDRAARFLTAHLGAGHPDAGRLAPVR" FT misc_feature 155596..155646 FT /note="PS01173 Lipolytic enzymes 'G-D-X-G' family, putative FT histidine active site" FT CDS 156378..157805 FT /transl_table=11 FT /gene="SCO3416" FT /gene_synonym="SCE9.23" FT /gene_synonym="gad" FT /product="putative glutamate decarboxylase" FT /note="SCE9.23, gad, probable glutamate decarboxylase, len: FT 475 aa; similar to many e.g. SW:DCEA_ECOLI (EMBL:M84024), FT gadA, Escherichia coli glutamate decarboxylase alpha (466 FT aa), fasta scores; opt: 1433 z-score: 1665.2 E(): 0, 50.0% FT identity in 426 aa overlap. Contains Pfam match to entry FT PF00282 pyridoxal_deC, Pyridoxal-dependent decarboxylase FT conserved domain, score 276.70, E-value 1.1e-79" FT /db_xref="GOA:Q9X8J5" FT /db_xref="HSSP:1PMM" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:Q9X8J5" FT /protein_id="CAB42769.1" FT /translation="MSLHQGPRPSRDSDRDRRRLAVNPFHAAANPLGGMTEAPPAHRLP FT DSPLPPESAYRLVHDELMLDGNARLNLATFVTTWMEPQAGVLMSECRDKNMIDKDEYPR FT TAELERRCVAMLADLWHAPDPSTAVGCSTTGSSEACMLAGMALKRRWALRNADRYPAKD FT VRPNLVMGVNVQVCWDKFCNFWEVEARQVPMEGDRFHLDPQAAAELCDENTIGVVGILG FT STFDGSYEPVADLCAALDALQERTGLDVPVHVDGASGAMVAPFLDEDLVWDFRLPRVAS FT INTSGHKYGLVYPGVGWALWRDAEALPEELVFRVNYLGGDMPTFALNFSRPGAQVVAQY FT YNFLRLGREGYRAVQQSARDIAGSLAERVAALGDFRLLTRGDQLPVFAFTTADDVTAYD FT VFDVSRRLREGGWLVPAYTFPPHREDLSVLRVVCRNGFSADMADLLLADLERLLPELRR FT QPGPLTRDKGAATGFHH" FT misc_feature 156510..157502 FT /note="Pfam match to entry PF00282 pyridoxal_deC, FT Pyridoxal-dependent decarboxylase conserved domain, score FT 276.70, E-value 1.1e-79" FT CDS complement(157953..158735) FT /transl_table=11 FT /gene="SCO3417" FT /gene_synonym="SCE9.24c" FT /product="putative ABC transporter transmembrane component" FT /note="SCE9.24c, probable ABC transporter transmembrane FT component, len: 315 aa; similar to many e.g. SW:DRRB_STRPE FT (EMBL:M73758), drrB, Streptomyces peucetius daunorubicin FT resistance transmembrane protein (283 aa), fasta scores; FT opt: 507 z-score: 565.3 E(): 3.6e-24, 35.6% identity in 264 FT aa overlap. Contains hydrophobic, possible FT membrane-spanning regions" FT /db_xref="GOA:Q9X8J6" FT /db_xref="InterPro:IPR013525" FT /db_xref="UniProtKB/TrEMBL:Q9X8J6" FT /protein_id="CAB42770.1" FT /translation="MSTGSTSPAMYALTDSWTMTRRELARWGRQPVTVVVSLVFPVMLL FT LMFGYLVGGGRGVSGEYVDYLVPGMLALTMAFGLEGTMIAVTQDLNKGVVDRFRSLPMT FT NGAVLVGRSAADMLQSALGLTALIGVGYALGWRAHGGPGAFLGAVGLLLLFRFAMLWIG FT IFLALVAGKPELVQAVQILVWPVGFLSNAFATPDSMPGWLGTVVEWNPMSQTATAVRDL FT FGGPGGESGHLWAAVAWPLALLAVFFPLAVGRFARLSR" FT CDS complement(158732..159679) FT /transl_table=11 FT /gene="SCO3418" FT /gene_synonym="SCE9.25c" FT /product="putative ABC transporter ATP-binding component" FT /note="SCE9.25c, probable ABC transporter ATP-binding FT component, len: 315 aa; similar to many e.g SW:DRRA_STRPE FT (EMBL:M73758), drrA, Streptomyces peucetius daunorubicin FT resistance ATP-binding protein (330 aa), fasta scores; opt: FT 942 z-score: 1020.6 E(): 0, 51.4% identity in 317 aa FT overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 187.90, E-value 1.6e-52, PS00211 ABC FT transporters family signature and PS00017 ATP/GTP-binding FT site motif A (P-loop)" FT /db_xref="GOA:Q9X8J7" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9X8J7" FT /protein_id="CAB42771.1" FT /translation="MTVADAAITVEGARKEYGSKSALDGLDLTVTRGTVHGVLGPNGAG FT KTTLVRILSTLLRPDAGRVEVAGHDVVAEAYAVRLRIGLLGQHAALDEELGGRQNLEMF FT GRLHHLGARGARARADELLVRFGLSDTGRKPVGAYSGGMRRRLDLAASLITEPEVLFLD FT EPTTGLDPRGRAEVWDSVRSLVGAGTTVLLTTQYLEEADQLADRISVVDAGRVVADGTA FT DELKAATGGDRVDVVLRDAGHLGAAVALLPLTGVRVDPDRRLLSAPVTDRMAALSGVVR FT ALEEAGIEAEDVALRRPTLDEVFLHLTDRTKEAA" FT RBS complement(158740..158745) FT /note="possible RBS" FT misc_feature complement(159038..159583) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 187.90, E-value 1.6e-52" FT misc_feature complement(159221..159265) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(159539..159562) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(159767..160408) FT /transl_table=11 FT /gene="SCO3419" FT /gene_synonym="SCE9.26c" FT /product="hypothetical protein" FT /note="SCE9.26c, hypothetical protein, len: 213 aa; unknown FT function, weakly similar to TR:P7170 (EMBL:Z80775) FT Mycobacterium tuberculosis hypothetical protein (180 aa), FT fasta scores; opt: 154 z-score: 195.5 E(): 0.0014, 27.0% FT identity in 178 aa overlap. The start codon is uncertain as FT there are 2 potential" FT /db_xref="InterPro:IPR005149" FT /db_xref="UniProtKB/TrEMBL:Q9X8J8" FT /protein_id="CAB42772.1" FT /translation="MSAIRLLVLGAVRQHGRAHGYQVRNDLEYWGAHEWSNAKPGSIYH FT ALKQMAKQGLLLAHEIAPSTAGGPPRVEYEITGQGTEEYLSLLRAYLTAYDQRPDVLTA FT ALGFMVDLPREEALALLKERVRKIEEWRASVTEYYMPAEGPGQYGHIGEIMNYWVHSAD FT SGAEWTRGLIERVRGGAYTFAGEGEPFVGVLAEGEENPFAAGRPHYGDAR" FT CDS complement(160491..161951) FT /transl_table=11 FT /gene="SCO3420" FT /gene_synonym="SCE9.27c" FT /product="putative aldehyde dehydrogenase" FT /note="SCE9.27c, probable aldehyde dehydrogenase, len: 486 FT aa; highly similar to many NAD-linked aldehyde FT dehydrogenases e.g. SW:XYLC_PSEPU (EMBL:U15151), xylC, FT Pseudomonas putida benzaldehyde dehydrogenase [NAD+] from FT TOL plasmid pWW0 (487 aa), fasta scores; opt: 1244 z-score: FT 1420.3 E(): 0, 41.5% identity in 479 aa overlap. Similar to FT others from S.coelicolor e.g. TR:O88069 (EMBL:AL031541) FT probable aldehyde dehydrogenase (483 aa) (40.0% identity in FT 448 aa overlap). Contains Pfam match to entry PF00171 FT aldedh, Aldehyde dehydrogenase, score 491.30, E-value FT 7.6e-144, PS00687 Aldehyde dehydrogenases glutamic acid FT active site and PS00070 Aldehyde dehydrogenases cysteine FT active site" FT /db_xref="GOA:Q9X8J9" FT /db_xref="HSSP:1A4S" FT /db_xref="InterPro:IPR016162" FT /db_xref="UniProtKB/TrEMBL:Q9X8J9" FT /protein_id="CAB42773.1" FT /translation="MSSYFTDLAQQYIDGEWRPGTGSWDIIDFNPYDNEKLASITIATV FT DEVDAAYRAAERAQRQWAATNPYARRAVFEKALRLVEEREAEIGEAIVAELGGTRLKAA FT FELHLAKEFLREAVHLALAPEGRIIPSPVDGKENRVYRVPVGVVGVISPFNFPFLLSLK FT SVAPALALGNAVVLKPHQNTPIVGGTLVAKILEDAGLPGGLLNVVVTDIAEIGDAFIEH FT PVPKVISFTGSDKVGRHVATVCAANFKRSVLELGGNSALVVLDDADVDYAVDAAVFSRF FT VHQGQVCMAANRVLVDRAVADEFTEKFVAKVSGLKVGDPRDPSTVIGPVINSSQADALS FT GVVEQALAEGATALVRGSVTDNLVEPSVLTGLPADSALLRQEVFGPVAFLVPFDGEEEA FT VRLVNDTPYGLSGAVHTGDVERGVNFAKRIDTGMFHVNDGTVHDEPIVPFGGEKHSGLG FT RLNGDTMLDAFTTQKWISVQHGRSGFPF" FT misc_feature complement(160515..161906) FT /note="Pfam match to entry PF00171 aldedh, Aldehyde FT dehydrogenase, score 491.30, E-value 7.6e-144" FT misc_feature complement(161076..161111) FT /note="PS00070 Aldehyde dehydrogenases cysteine active FT site" FT misc_feature complement(161172..161195) FT /note="PS00687 Aldehyde dehydrogenases glutamic acid active FT site" FT RBS complement(161958..161961) FT /note="possible RBS" FT CDS complement(162027..162851) FT /transl_table=11 FT /gene="SCO3421" FT /gene_synonym="SCE9.28c" FT /product="conserved hypothetical protein" FT /note="SCE9.28c, hypothetical protein, len: 274 aa; similar FT others from S.coelicolor e.g. TR:O86719 (EMBL:AL031515), FT SC5C7.22C, hypothetical protein (287 aa), fasta scores; FT opt: 727 z-score: 871.9 E(): 0, 44.7% identity in 273 aa FT overlap" FT /db_xref="GOA:Q9X8K0" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q9X8K0" FT /protein_id="CAB42774.1" FT /translation="MLLGSQLRRLRETRGITREAAGYSIRASESKISRMELGRVSFKTR FT DVEDLLTLYGITDEQERASLLSLAKEANVAGWWHSYSDVLPSWFPTYVGLEGAASLIRA FT YEVQFVHGLLQTEEYARAVVRRGMKGAGEADVERRVALRLERQKHLVAENAPEFHIVLD FT EAALRRPYGDREVMRGQLQHLIEVSERPNVRLQVMPFGFGGHSGESGAFTLLSFPESDL FT SDVVYLEQLTSALYLDKQEDVTQYETALKELQQDSPGPDESRDLLRGLLQLS" FT CDS complement(162961..163164) FT /transl_table=11 FT /gene="SCO3422" FT /gene_synonym="SCE9.29c" FT /product="hypothetical protein" FT /note="SCE9.29c, hypothetical protein, len: 67 aa; FT improbable CDS suggested by GC frame plot alone" FT /db_xref="UniProtKB/TrEMBL:Q9X8K1" FT /protein_id="CAB42775.1" FT /translation="MVRDHGFGCVPQMQGQMHVHVTEMDLPVPLVGQFFRHLRLPFIAR FT DGRFWPTACMILCISFGSIPFP" FT CDS 163229..163693 FT /transl_table=11 FT /gene="SCO3423" FT /gene_synonym="SCE9.30" FT /product="putative regulator" FT /note="SCE9.30, possible regulator, len: 154 aa; similar to FT TR:Q53897 (EMBL:X60316), AbaA, Streptomyces coelicolor ORFA FT from AbaA regulatory locus for antibiotic production (192 FT aa), fasta scores; opt: 278 z-score: 352.7 E(): 2.5e-12, FT 39.9% identity in 148 aa overlap. Also similar to several FT S. coelicolor hypothetical proteins including the FT N-terminus of TR:O86807 (EMBL:AL031031), SC7C7.02c, FT possible regulatory protein (916 aa) (35.0% identity in 137 FT aa overlap). Contains TTA (leucine) codon, possible target FT for bldA regulation, near N-terminus" FT /db_xref="GOA:Q9X8K2" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9X8K2" FT /protein_id="CAB42776.1" FT /translation="MLEPLRQGLPPLDPAAVSNAASCALPPRYEAVREARRFTRRTLDG FT WDTGDRFDDVCLVVSELVTNALRHALPADTPRHDEQHGPVRLHLMRWTERLVCAVRDPS FT HDSPVARETDDFSAESGRGLFLVDSFSDSWGWHPLAGTLNGKVVWALFRI" FT misc_feature 163241..163243 FT /note="TTA (leucine) codon, possible target for bldA FT regulation" FT CDS complement(163742..163993) FT /transl_table=11 FT /gene="SCO3424" FT /gene_synonym="SCE9.31c" FT /product="putative regulator" FT /note="SCE9.31c, possible regulator, len: 83 aa; similar to FT TR:Q53896 (EMBL:X60316), abaA, Streptomyces coelicolor ORFD FT from AbaA regulatory locus for antibiotic production (75 FT aa), fasta scores; opt: 307 z-score: 422.3 E(): 3.4e-16, FT 64.9% identity in 74 aa overlap and to TR:Q53842 FT (EMBL:U28930), BldB, S.coelicolor developmental protein (98 FT aa) (41.8% identity in 67 aa overlap)" FT /db_xref="InterPro:IPR007278" FT /db_xref="UniProtKB/TrEMBL:Q9X8K3" FT /protein_id="CAB42777.1" FT /translation="MDHDVYDVYNGMAATQLHDAAWQKSRRSNSQGSCVEFARLPDGAV FT AVRNSRFPDGPALVYTRAEIEAMLLGVKDGEFDHLIAS" FT CDS complement(164298..164537) FT /transl_table=11 FT /gene="SCO3425" FT /gene_synonym="SCE9.32c" FT /gene_synonym="rpsR2" FT /product="putative 30S ribosomal protein S18" FT /note="SCE9.32c, rpsR2, probable 30S ribosomal protein S18, FT len: 79 aa; similar to many e.g. SW:RS18_BACSU FT (EMBL:D26185), rpsR, Bacillus subtilis 30S ribosomal FT protein S18 (78 aa), fasta scores; opt: 234 z-score: 321.6 FT E(): 1.4e-10, 51.4% identity in 72 aa overlap. Similar to FT S.coelicolor SCH24.11c, rpsR, probable 30S ribosomal FT protein S18 (78 aa) (61.8% identity in 68 aa overlap). FT Contains Pfam match to entry PF01084 Ribosomal_S18, FT Ribosomal protein S18, score 109.50, E-value 6.4e-29 and FT PS00057 Ribosomal protein S18 signature" FT /db_xref="GOA:Q9X8K4" FT /db_xref="InterPro:IPR018275" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8K4" FT /protein_id="CAB42778.1" FT /translation="MPRPRKADRTPARQRPNPLDRDGVTYVDYKDTELLRKFVSDRGKI FT RSRRVTRVTSQQQRQLARAIKNAREMALLPYGTR" FT misc_feature complement(164316..164477) FT /note="Pfam match to entry PF01084 Ribosomal_S18, Ribosomal FT protein S18, score 109.50, E-value 6.4e-29" FT misc_feature complement(164388..164459) FT /note="PS00057 Ribosomal protein S18 signature" FT CDS complement(164619..165731) FT /transl_table=11 FT /gene="SCO3426" FT /gene_synonym="SCE9.33c" FT /product="hypothetical protein" FT /note="SCE9.33c, conserved hypothetical protein, len: 370 FT aa; similar to hypothetical proteins in Burkholderia, FT Mycobacterium tuberculosis and Bacillus subtilis. Similar FT to SW:P47K_PSECL (EMBL:D90216) Pseudomonas chlororaphis 47 FT kD protein critical for the expression of nitrile hydratase FT genes (419 aa), fasta scores; opt: 374 z-score: 409.4 E(): FT 1.8e-15, 28.1% identity in 392 aa overlap" FT /db_xref="InterPro:IPR011629" FT /db_xref="UniProtKB/TrEMBL:Q9X8K5" FT /protein_id="CAB42779.1" FT /translation="MSEPGRFHEPPVVIVGGLHADARRAAVARLLADVPGSVVLHHDLA FT TAAAGTVVRTVRDATGILAAGEAPLVNDCACCALREDLVPELVRLAEAGGTPLAVVELW FT DSVEPKAMAEVVTAGGFTVAGVVTAVDPALVLPYLGNGDDLAEGGLAAAATDQRTVADT FT FARQLEYASVLALAEPLPGSPEADDEDRELLAQLHPTARRVPIGHGNPAGTPPAGPELA FT RAALAGFDVEAAAAAQHPACALLPAEADAHGVATLVWHRRRPFHPERLYAALEDLTCAA FT ARSRGRFWLAGKGDTLLHWDAAGGALCVESAGPWLASLPDAAWELVPPVRRAAAALDWH FT PEHGDRCQHLVFTSPGLDRDGLERLLESCL" FT CDS complement(165728..165982) FT /transl_table=11 FT /gene="SCO3427" FT /gene_synonym="SCE9.34c" FT /gene_synonym="rpmE" FT /product="putative 50S ribosomal protein L31" FT /note="SCE9.34c, rpmE, probable 50S ribosomal protein L31, FT len: 84 aa; similar to many e.g. SW:RK31_GUITH FT (EMBL:U81044) Guillardia theta chloroplast 50S ribosomal FT protein L31 (72 aa), fasta scores; opt: 149 z-score: 220.0 FT E(): 6.2e-05, 48.8% identity in 43 aa overlap. Contains FT Pfam match to entry PF01197 Ribosomal_L31, Ribosomal FT protein L31, score 59.20, E-value 8.7e-14 and PS01143 FT Ribosomal protein L31 signature" FT /db_xref="GOA:Q9X8K6" FT /db_xref="InterPro:IPR002150" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8K6" FT /protein_id="CAB42780.1" FT /translation="MRKGIHPEYRPVVFRDRAADYAFLTRSTMTSERTVEWEDGRTYPV FT VDVEVSHVSHPFYTGTARVLDTAGRVERFERRYGKQDGA" FT misc_feature complement(165740..165982) FT /note="Pfam match to entry PF01197 Ribosomal_L31, Ribosomal FT protein L31, score 59.20, E-value 8.7e-14" FT misc_feature complement(165764..165820) FT /note="PS01143 Ribosomal protein L31 signature" FT CDS complement(165989..166153) FT /transl_table=11 FT /gene="SCO3428" FT /gene_synonym="SCE9.35c" FT /gene_synonym="rpmG" FT /product="putative 50S ribosomal protein L33" FT /note="SCE9.35c, rpmG, probable 50S ribosomal protein L33, FT len: 54 aa; similar to many e.g. SW:RL33_ECOLI FT (EMBL:J01677), rpmG, Escherichia coli 50S ribosomal protein FT L33 (54 aa), fasta scores; opt: 162 z-score: 270.5 E(): FT 9.5e-08, 46.9% identity in 49 aa overlap. Contains Pfam FT match to entry PF00471 Ribosomal_L33, Ribosomal protein FT L33, score 37.80, E-value 2e-08" FT /db_xref="GOA:Q9X8K7" FT /db_xref="InterPro:IPR018264" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8K7" FT /protein_id="CAB42781.1" FT /translation="MARNELRPVIKLRSTAGTGYTYVTRKNRRNDPDRLVLRKYDPAAG FT RHVDFREER" FT misc_feature complement(165992..166135) FT /note="Pfam match to entry PF00471 Ribosomal_L33, Ribosomal FT protein L33, score 37.80, E-value 2e-08" FT misc_feature 166241..166414 FT /note="Pfam match to entry PF00830 Ribosomal_L28, Ribosomal FT L28 family, score 88.70, E-value 1.2e-22" FT CDS 166241..166462 FT /transl_table=11 FT /gene="SCO3429" FT /gene_synonym="SCE9.36" FT /gene_synonym="rpmB" FT /product="putative 50S ribosomal protein L28" FT /note="SCE9.36, rpmB, probable 50S ribosomal protein L28, FT len: 73 aa; similar to many e.g. SW:RL28_ECOLI FT (EMBL:J01677), rpmB, Escherichia coli 50S ribosomal protein FT L28 (77 aa), fasta scores; opt: 235 z-score: 344.6 E(): FT 7.1e-12, 47.8% identity in 69 aa overlap. Contains Pfam FT match to entry PF00830 Ribosomal_L28, Ribosomal L28 family, FT score 88.70, E-value 1.2e-22" FT /db_xref="GOA:Q9X8K8" FT /db_xref="InterPro:IPR001383" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8K8" FT /protein_id="CAB42782.1" FT /translation="MLTGARPGFGNRISHSHRRTSRRFDPNIQTKRYWLPSENRHVRLR FT LSTKGIRTVDSIGVEAAVARIRARGVRI" FT misc_feature 166462..166764 FT /note="Pfam match to entry PF00253 Ribosomal_S14, Ribosomal FT protein S14, score 103.10, E-value 1.5e-30" FT CDS 166462..166767 FT /transl_table=11 FT /gene="SCO3430" FT /gene_synonym="SCE9.37" FT /gene_synonym="rpsN" FT /product="putative 30S ribosomal protein S14" FT /note="SCE9.37, rpsN, probable 30S ribosomal protein S14, FT len: 101 aa; similar to many e.g. SW:RS14_ECOLI FT (EMBL:X01563), rpsN, Escherichia coli 30S ribosomal protein FT S14 (100 aa), fasta scores; opt: 299 z-score: 377.0 E(): FT 1.1e-13, 44.0% identity in 100 aa overlap. Contains Pfam FT match to entry PF00253 Ribosomal_S14, Ribosomal protein FT S14, score 103.10, E-value 1.5e-30" FT /db_xref="GOA:Q9X8K9" FT /db_xref="InterPro:IPR018271" FT /db_xref="UniProtKB/Swiss-Prot:Q9X8K9" FT /protein_id="CAB42783.1" FT /translation="MAKKSKIAKNEQRREIVARYAARRAELKEVLRRPSSTEAERLAAQ FT RELRRQPRDASPTRVRNRDQIDGRPRGYLRVFGLSRVNLREQAHAGHLPGVRKSSW" FT CDS 166769..167503 FT /transl_table=11 FT /gene="SCO3431" FT /gene_synonym="SCE9.38" FT /product="possible membrane protein" FT /note="SCE9.38, possible membrane protein, len: 244 aa; FT unknown function, contains a hydrophobic, possible FT membrane-spanning region. Contains PS00213 Lipocalin FT signature, so may be involved in transport of small, FT hydrophobic molecules" FT /db_xref="UniProtKB/TrEMBL:Q9X8L0" FT /protein_id="CAB42784.1" FT /translation="MRLFGAERPSGYSLELPVTWVTAGNTASTENTASAESTSGAWRTG FT VAAGTASATAPGTDVRSGGVAFRRSRRTRRSVRVAALSLGLVGALALTACTDGGDSDGG FT GSGEGSGGDKSSAAPGASASTDPGGDAGGSPSAGAAGELEGSWLATTDGQAVALMVTGD FT KAALFATGGTVCSGTTEETSGTRTIRLKCADGSADRATGKVGAVGATSLTVAWEGALGK FT ETYTRSEGGSLPPGLPTAGIGS" FT misc_feature 167180..167218 FT /note="PS00213 Lipocalin signature" FT CDS complement(167462..168718) FT /transl_table=11 FT /gene="SCO3432" FT /gene_synonym="SCE9.39c" FT /product="hypothetical protein" FT /note="SCE9.39c, hypothetical protein, len: 418 aa; unknown FT function, C-terminal end similar to TR:O07428 (EMBL:Z97050) FT Mycobacterium tuberculosis hypothetical protein (249 aa), FT fasta scores; opt: 231 z-score: 252.5 E(): 9.7e-07, 30.4% FT identity in 270 aa overlap. Contains probable coiled-coil FT from 254 to 283 (30 residues) (Max score: 1.418, FT probability 0.78)" FT /db_xref="UniProtKB/TrEMBL:Q9X8L1" FT /protein_id="CAB42785.1" FT /translation="MSTPRTVDRAFETALYDTADDALDTAASLLAADPAADAELARRGR FT EFVATAWRRGWQPADLVRIVRRELDDVHVRLVAALILAQAPDDRARGPRWAAQLDDLPG FT GDGAAPPRTDRFSHATAVLELYRLLLRLPGLEPLEAGEGPRGGRGNRPESRALARIRAL FT LAKAEATGYPEEAEALSAKAQELMARHSVDEALLAAQAHGHASSPDAPGACRIGVEPPY FT EQAKAVLLDAVADANHCGAVWNEPFGFSTVVGFEADLEAVELLYTSLLVQAEAAMTKAE FT AGQRAGGRKRTKTFRQSFLAAYAHRAGTRLRAAAQAATRAATEAATEAATTGASGPADA FT DLLPVLASREAAVTDRMERMFPQTTTTRLRGAADAAGWTEGTRAADAARVGRHRPLERT FT RRPEPRSGSDAGGRQSRRQ" FT CDS 168805..169581 FT /transl_table=11 FT /gene="SCO3433" FT /gene_synonym="SCE9.40" FT /product="conserved hypothetical protein" FT /note="SCE9.40, conserved hypothetical protein, len: 258 FT aa; unknown function, C-terminus similar to N-terminal FT region of the clpC family of ATP-dependent Clp protease FT ATP-binding subunits e.g. TR:Q48760 (EMBL:U40604), mec, FT Listeria monocytogenes clpC ATPase (825 aa), fasta scores; FT opt: 272 z-score: 311.0 E(): 5.3e-10, 36.4% identity in 140 FT aa overlap. A hypothetical protein of similar length occurs FT in Mycobacterium tuberculosis; TR:P71964 (EMBL:Z80225) clpC FT family hypothetical protein (252 aa) (57.3% identity in 255 FT aa overlap). Contains probable helix-turn-helix motif at aa FT 62-83 (Score 1144, +3.08 SD)" FT /db_xref="GOA:Q9X8L2" FT /db_xref="InterPro:IPR004176" FT /db_xref="UniProtKB/TrEMBL:Q9X8L2" FT /protein_id="CAB42786.1" FT /translation="MTTNPSITSSVRLDELITAIKKVHPEPLEQLQDAVIAGEHLGEVA FT DHLIGHFVDQARRSGASWTDIGKSMGVTRQAAQKRFVTKESADLDAGQGFSRYTPRARN FT VVMTAHNAAKTAGNAEGLPEHLVLGLVTERESLSAKAIAAQGVTLDAIHEAATAALPPA FT AAEVPELVPYGPAAKKVLELTFREALRLGHNYIGTEHILLALLEHEHGEGVLSGLGLDK FT EATERYVVDAVAEFIHLTEKAEKAGASREGGAAGEA" FT repeat_region 169588..169704 FT /note="approx. 10 x 15 bp degenerate direct repeats" FT CDS 169783..171474 FT /transl_table=11 FT /gene="SCO3434" FT /gene_synonym="SCE36.01" FT /gene_synonym="SCE9.41" FT /product="putative DNA polymerase I" FT /note="SCE36.01, partial CDS, possible DNA polymerase I, FT len: >328 aa; similar to the C-terminal region many e.g. FT SW:DPO1_CHLAU DNA polymerase I from Chloroflexus FT aurantiacus (942 aa) fasta scores; opt: 287, z-score: FT 322.2, E(): 1.3e-10, (28.9% identity in 305 aa overlap). FT Contains two Pfam matches to entry PF00476 DNA_pol_A, DNA FT polymerase family A." FT /note="SCE9.41, hypothetical protein, partial CDS, len: FT >268 aa; unknown function, probable CDS suggested by FT positional base preference, GC frame analysis and amino FT acid composition" FT /db_xref="GOA:Q8CJW7" FT /db_xref="HSSP:1TAU" FT /db_xref="InterPro:IPR001098" FT /db_xref="UniProtKB/TrEMBL:Q8CJW7" FT /protein_id="CAD55317.1" FT /translation="MAERWALAVAEGGGVEVAPLGPDGLPTGPVRREPGLAEAVRARPD FT VARWVWRSTAETAPRLLAAGVRVERCYDVEAAETLLLGHEGRYGEPRSAAAALARLRGG FT PVPPDPPQRSAEPGAQSSLFEPQAVHLPLSDLLAVYAEQQRRHDRSALPDRLRLLTAAE FT SAGMLVAAEMNRAGLPWRADVHREVLHDLLGERYAGGGEPRRLAELAEEVSAAFGRRVR FT PDLPADVVKAFGQAGVKVGSTRRWELESLDHPAVKPLIEYKKLYRIWVAHGWSWLQDWV FT RDGRFRPEFLAGGTVTGRWVTNGGGGLQIPKVIRRAVVADPGWRLVVADADQMEPRVLA FT AISRDPGLMEVAGRETDLYQSVSDRAFSGDRDQAKLAVLGAVYGQTSGDGLKNLAALRR FT RFPRAVAYVDDAARAGEEGRLVRTWLGRTCPPAAGAADGTEEAGLPQDEPAGAGDRAQE FT WVPGYASTNARARGRFARNFVVQGSAADWALLLLAALRQTCADMAAELVFFQHDEVIVH FT CPEEEAATVVAAIRDAAELAGRLTFGATPVRFPFTTAVVECYADAK" FT misc_feature 170488..170586 FT /note="overlap with S.coelicolor cosmid StE36 from 1 to 99 FT StE36" FT misc_feature 170722..170934 FT /note="Pfam match to entry PF00476 DNA_pol_A, DNA FT polymerase family A, score 37.60, E-value 1.7e-09." FT misc_feature 171154..171348 FT /note="Pfam match to entry PF00476 DNA_pol_A, DNA FT polymerase family A, score 20.30, E-value 0.00012." FT CDS 171565..172452 FT /transl_table=11 FT /gene="SCO3435" FT /gene_synonym="SCE36.02" FT /product="putative transcriptional regulator" FT /note="SCE36.02, probable transcriptional regulator, len: FT 295 aa; similar to many e.g. SW:GLTC_BACSU glutamate FT biosynthesis transcriptional regulator from Bacillus FT subtilis (300 aa) fasta scores; opt: 456, z-score: 520.3, FT E(): 1.2e-21, (31.9% identity in 288 aa overlap). Contains FT Pfam match to entry PF00126 HTH_1, Bacterial regulatory FT helix-turn-helix proteins, lysR family and Prosite match to FT PS00044 Bacterial regulatory proteins, lysR family FT signature." FT /db_xref="GOA:Q9X8B5" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9X8B5" FT /protein_id="CAB42071.1" FT /translation="MDLLSLRYFQSVARHQHISRAAEELRVAQPSVSRTIIRLESELGT FT PLFDRRGRRIRLNEHGAAFLVRVERALAELEDARREVADAGRGGPGRVAVAAETLLQLA FT GVLSAFRELRPGVGVRLFQAPVDSMRRHLRSGEVDFALASQPLTGPEVCSAELAREEVL FT LAVPVGHRLAGRERVAVAELADEDFVSTRPGHWQRALLERLFAREGLAPRVVCEGDEAA FT ATPELVGAGVGIGLMPAVARRVLGEDGPVGWLRLDAPDCHRTLTLVWRRDAYLSPAALD FT FRRLAGERLMPDVS" FT misc_feature 171571..171990 FT /note="Pfam match to entry PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix proteins, lysR family, score FT 124.10, E-value 2.6e-33." FT misc_feature 171613..171705 FT /note="PS00044 Bacterial regulatory proteins, lysR family FT signature." FT CDS 172540..174093 FT /transl_table=11 FT /gene="SCO3436" FT /gene_synonym="SCE36.03" FT /product="putative fatty acid CoA ligase" FT /note="SCE36.03, possible fatty acid CoA ligase, len: 517 FT aa; similar to many eg. TR:O86483 (EMBL:AJ007932) acyl CoA FT ligase from Streptomyces argillaceus mithramycin FT biosynthesis cluster (514 aa) fasta scores; opt: 625, FT z-score: 678.0, E(): 1.9e-30, (32.7% identity in 513 aa FT overlap). Contains Pfam match to entry PF00501 AMP-binding, FT AMP-binding enzyme and Prosite match to PS00455 Putative FT AMP-binding domain signature." FT /db_xref="GOA:Q9X8B6" FT /db_xref="HSSP:1LCI" FT /db_xref="InterPro:IPR000873" FT /db_xref="UniProtKB/TrEMBL:Q9X8B6" FT /protein_id="CAB42072.1" FT /translation="MSRQHGTTQTRFSTYTEALLDVLSAAPSRPVLTTADGSVISAGAL FT RDRVCRLGGELERRGVGRGDTVGLLTGNSADGLAARYAANLTGARVVVLYEGMSTSVMA FT RILASVDGALLLVDDLRHDVARELLPLPGVPPVLSLGPSNFAEDVLAAAARHPTRAMRP FT TRAPVGPDDDWRIGYTGGTTGIPKGIRMSHGSYRRSLERRLTGAGDPPRFLACTSLAHL FT AGIFADTALLEGGSVVLRHDFEPGDVLATVERERITHTWLLPPLLYRLLDHPDLSATDL FT SSLSRVTYGGTAAAPTRLRQAAGLLGPVLYGLYGQAEAQLISETGPDEQELTGREGHPT FT VGRAVPGVEILVQDTDGTPMKPGTPGEVLVRSPYAMHGYWKQPELTREVLRDGWVHTGD FT VGYLDENGYLYIVDRIKEMIVVVGGHVYPAELEALLLNHPSVAQCTVFGSRDEESVEHV FT HAAVVPVRGHTPSLEEIHAFVTARKGRLYAPETVHLVPAIPLTAVGKPDKRRLRSLLPG FT " FT misc_feature 172660..173877 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 48.50, E-value 2.3e-17." FT misc_feature 173065..173100 FT /note="PS00455 Putative AMP-binding domain signature." FT CDS complement(174765..175505) FT /transl_table=11 FT /gene="SCO3437" FT /gene_synonym="SCE36.04c" FT /product="putative integral membrane protein" FT /note="SCE36.04c, possible integral membrane protein, len: FT 246aa; contains possible membrane spanning hydrophobic FT regions." FT /db_xref="UniProtKB/TrEMBL:Q9X8B7" FT /protein_id="CAB42073.1" FT /translation="MRRPARAVADLLASGLVLAGATAAGSLLFAIAEGGYATLPDLVRE FT VGLPGAVAVAVAPLIALRLSGPRLGRAVLLGAAAGVAGTAVLELVREVGFRIFESMPGD FT LPMLMGVLLRDQIMQGPDTASNIAGWTYHVWNSGMFGVTYAVLLGGFPFRRFGGAVAGT FT LMGTGYGLALGTGFLLSPVPKAVGAGVFGTDFGAKFAITVYLAHAGFGALLGWLVHRYG FT NRIAPLWSVACKLLPPRGIRKENN" FT CDS complement(175502..176725) FT /transl_table=11 FT /gene="SCO3438" FT /gene_synonym="SCE36.05c" FT /product="hypothetical protein" FT /note="SCE36.05c, unknown, len: 407aa; contains a repeat FT region." FT /db_xref="InterPro:IPR005180" FT /db_xref="UniProtKB/TrEMBL:Q9X8B8" FT /protein_id="CAB42074.1" FT /translation="MPQRKDPSWEAAFRDTPRSPGRGRREADCVRQVTVRTAIAVLSGF FT PSCRPLPQRRGRQVNDSRPRQGAVPSDNPEGLASMVLIPRTLRIRRPRHTGIAVGVVAL FT ALTATACGSNDSSDTAGSEQTASPTAVSEEPAAPAEAAQTAFTSYASKRPFGDTVSALK FT KAVADNGMMILGDLNQAGALKSTGLNLKGAQSFFVGNPAKGKVFFDANPAIGTVIPLRM FT YVWAGDDGNSHVGYFDPAAMFTAVDPGLAEGGKQMAMAADKIAQGATGGSAQPGSKVAA FT SFVSVASAKSFPDTEKALKKSVADNGMMILGDLNQAGALKSTGLHLKGARSYFVGNPTK FT GKMFFEANPAIGTVIPLRMYVWAGADGKAHIGYYDPAPLFQAVDAKLADGGEQMKMAAS FT KIAEGAAK" FT repeat_region 175687..176087 FT /note="Single degenerate direct repeat." FT CDS 176807..177679 FT /transl_table=11 FT /gene="SCO3439" FT /gene_synonym="SCE36.06" FT /product="hypothetical protein" FT /note="SCE36.06, unknown, len: 290aa;" FT /db_xref="GOA:Q9X8B9" FT /db_xref="InterPro:IPR011707" FT /db_xref="UniProtKB/TrEMBL:Q9X8B9" FT /protein_id="CAB42075.1" FT /translation="MGGLGAGGALAGLGWAYADGGPLVADGKPPRAPAHEGAPLRDLPE FT VRSREGRPEHTLTVATTRPVVGGRRLHLDTYNGQLPGALLRIRPGDRLRILLRNRMLPS FT GVPLNALPPLCADKAADGTEHAHSAAGGPLHCAPEAGHQVVDGHTIIQQALATNLHTHG FT LQVSPSGSADNVFVRLDPLEDHQYAYDIPFDHPAGLHWYHPHHHGSTTHQAWSGLAGPI FT VVEGDIDHVPEIAGMRERTIVLSMLRLDGNGENPTAVVLPTGGDDPFTTVPAVPTRMVA FT TLNGQLRPK" FT CDS 177739..178458 FT /transl_table=11 FT /gene="SCO3440" FT /gene_synonym="SCE36.07" FT /product="hypothetical protein" FT /note="SCE36.07, unknown, len: 239aa;" FT /db_xref="GOA:Q9X8C0" FT /db_xref="InterPro:IPR002355" FT /db_xref="UniProtKB/TrEMBL:Q9X8C0" FT /protein_id="CAB42076.1" FT /translation="MWLHVERHSLHQIGQDGIPFARTRTVRAIMVASANRAEFVIQGGA FT PGRYRIYAAGYDQGHPGGVRPDIELGTLVVTGRETTGRIPRQLVEPPRMPRLPVARRRT FT LVFSGDISGKHGLGVRFLIDGKLYDVDRIDQEVQAGTVEEWRIVNEDVFQHPLHIHVNP FT FQVIDVKGIPPRDTSWQTDPGIWWDTFRLPPDGEFTLRTYFRPDITGKTVFHCHILPHE FT DNGMMGNLLISPKGGAR" FT CDS 178455..179024 FT /transl_table=11 FT /gene="SCO3441" FT /gene_synonym="SCE36.08" FT /product="putative secreted protein" FT /note="SCE36.08, putative secreted protein, len: 189 aa. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="UniProtKB/TrEMBL:Q9X8C1" FT /protein_id="CAB42077.1" FT /translation="MSALASRLRLGVAAAAAATLLAGGSPGTAAPAPAPFGKAALPADP FT GTRDHPYVFTQQHRDGLWWWNGTWLPQSVPPGAHLQIQLPAGPAHWEPVTGRACRPTGA FT AGLLPVRARATALGTSVLPNEGRIDGFSTLEVFDYRVEGIGAAAICLQANPRPERPGDI FT GLPDQEPLVYVLTVLVRIPQASLPRL" FT CDS 179082..179426 FT /transl_table=11 FT /gene="SCO3442" FT /gene_synonym="SCE36.09" FT /product="hypothetical protein" FT /note="SCE36.09, unknown, len: 114aa;" FT /db_xref="GOA:Q9X8C2" FT /db_xref="HSSP:1NM3" FT /db_xref="InterPro:IPR012335" FT /db_xref="UniProtKB/TrEMBL:Q9X8C2" FT /protein_id="CAB42078.1" FT /translation="MPAPVRPDPAKVQMYWRPGCPYCAMLRRQLRRTGLSYEPVDIWKD FT QSGAAYVRSVNNGNETVPTVAVAGHPLTNPSARQVLEAVQRHAPHLLPETAPADAARRW FT RPRWPWRRTR" FT CDS complement(179723..181087) FT /transl_table=11 FT /gene="SCO3443" FT /gene_synonym="SCE36.10c" FT /product="putative pyridine nucleotide-disulphide FT oxidoreductase" FT /note="SCE36.10c, probable pyridine nucleotide-disulphide FT oxidoreductase, len: 454 aa; similar to many eg. FT SW:MERA_STRLI mercuric reductase from Streptomyces lividans FT (474 aa) fasta scores; opt: 752, z-score: 772.0, E(): 0, FT (34.5% identity in 464 aa overlap). Contains Pfam match to FT entry PF00070 pyr_redox, Pyridine nucleotide-disulphide FT oxidoreductase class-I." FT /db_xref="GOA:Q9X8C3" FT /db_xref="HSSP:1EBD" FT /db_xref="InterPro:IPR000815" FT /db_xref="UniProtKB/TrEMBL:Q9X8C3" FT /protein_id="CAB42079.1" FT /translation="MVQEIDVVVIGMGVGGEHVAERLAEEGLDVVGVEAELVGGECPYW FT VCIPSKMMIRGGNLLAEARRIPGMAGQAQVTPDFAPVASRIREEATDDWNDQVAVDRFT FT GKGGQFVRGRARLAGPKRVEIDGREFTARRGVVIATGSRPQIPPVPGLDAVPYWTNREA FT IAVKDSPRSLMVLGGGAVGVELAQAFARFGTAVTVVEAAERLLPAEEPETSALLADVLG FT AEGITVRTGAQANRARHDGDTFTLTLEGGEELTAERLLVATGRRAGLAGLGLGTVGLDP FT DARALHVDEQLRAAPGLWGVGDVTGRGAFTHVAMYQAEIAVRAILGQPGPGADYRALPR FT VTFTDPEVGSVGLTEARAREKGLRVRTGTAQVPSSARGWIHKAGNEGLIKLVEDVDRGV FT LVGATSAGPMGGEVLYGLVVAVQGEVPVDRLRHMMYAYPTFHRAVEDALRALRSS" FT misc_feature complement(179729..181069) FT /note="Pfam match to entry PF00070 pyr_redox, Pyridine FT nucleotide-disulphide oxidoreductase class-I, score 196.50, FT E-value 4.2e-55." FT CDS complement(181229..183082) FT /transl_table=11 FT /gene="SCO3444" FT /gene_synonym="SCE46.01c" FT /gene_synonym="SCE36.11c" FT /product="conserved hypothetical protein" FT /note="SCE46.01c, hypothetical protein (partial CDS), len: FT >38 aa ;similar to TR:CAB52841 (EMBL:AL109848) Streptomyces FT coelicolor hypothetical 68.4 kD protein; fasta scores: opt: FT 152 z-score: 252.5 E(): 1e-06; 52.8% identity in 36 aa FT overlap" FT /note="SCE36.11c, partial CDS, conserved hypothetical FT protein, len: 612aa; similar to TR:P71741 (EMBL:Z81368) FT hypothetical protein from Mycobacterium tuberculosis (642 FT aa) fasta scores; opt: 1283, z-score: 1479.1, E(): 0, FT (41.9% identity in 623 aa overlap) and SW:YAY3_SCHPO FT hypothetical protein from Schizosaccharomyces pombe (649 FT aa) fasta scores; opt: 883, z-score: 1017.4, E(): 0, (33.1% FT identity in 634 aa overlap)." FT /db_xref="GOA:Q8CJW6" FT /db_xref="InterPro:IPR011613" FT /db_xref="UniProtKB/TrEMBL:Q8CJW6" FT /protein_id="CAD55318.1" FT /translation="MMSSRIADYGMLADGSSAALVDRRGAIDWMCVPRFDSPALFARLL FT DPEAGHWSITPVGRFEATRRYLPGTLVVETTFTTASGVARLRDALAVPEGQRGHELGMS FT PPHELLREIEGVSGDVAFDVELVPRPEYGLVRPLLRLTDGGMRTFGGPNQIAVRSPVPL FT EAGEACVRAKLRVAAGQRFGFSLVWAPPEVAPPEPTTPERVAERIDDTVEAWRSWEAEH FT DIYQGPHRDLVLLSSRVLKGLTYRPTGAIVAAPTTSLPEAVGGTRNWDYRYAWIRDASL FT TLEALYHGSCPNEAADFVSFMTSSAGGTSGADSSLQIMYGVGGEHDLSERQLPHLRGWR FT DSRPVRVGNQAWAQTQLDVYGELLNALHLYQERLGDLHPEIQRFAAGLADTALRRWQEP FT DAGMWEMRGEPRHHLSSKVLCWVALDRAVKLAPRLGGHARPQAWAAERDRIHATVLERG FT WSERRGAYTQAFDSDELDAAALLMPLYGFLPATDARMNATIEAIARDLTDDGLVLRYRL FT IDDRNLDGLEGGEGTFVLCSFWLAAALAQAGRPDRAQALFDRVAGFANDLGLLAEEIDP FT RTGELLGNFPQAFSHIGLINAAAAIDQANGALPRHDADPAH" FT CDS complement(183218..183385) FT /transl_table=11 FT /gene="SCO3445" FT /gene_synonym="SCE46.02c" FT /product="putative small membrane protein" FT /note="SCE46.02c, putative small membrane protein, len: 55 FT aa. Contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9RKI7" FT /protein_id="CAB61853.1" FT /translation="MEVCLARSGFPQCRMTDFRLWEMEGEYTEFAVGAALLAGHATYGV FT VAALVCAAVL" FT CDS complement(183479..184156) FT /transl_table=11 FT /gene="SCO3446" FT /gene_synonym="SCE46.03c" FT /product="putative dehalogenase" FT /note="SCE46.03c, possible dehalogenase, len: 225 aa; FT similar to SW:HAD_PSESP (EMBL:S74078) Pseudomonas sp. FT (strain YL) 2-haloalkanoic acid dehalogenase (EC 3.8.1.2), FT 232 aa; fasta scores: opt: 243 z-score: 288.1 E(): FT 1.1e-08; 23.5% identity in 217 aa overlap. Contins match to FT Pfam entry PF00702 Hydrolase, haloacid dehalogenase-like FT hydrolase" FT /db_xref="GOA:Q9RKI6" FT /db_xref="InterPro:IPR005833" FT /db_xref="UniProtKB/TrEMBL:Q9RKI6" FT /protein_id="CAB61854.1" FT /translation="MPRQNAPLLVFDVNETLSDMSPLQSRFAEIGAPPHLFHLWFAGVL FT RDGFALTAAGAFSDFSAVAREGVRALLSSAPEWSGDIEQAAGHVVDGLSHLEVHPDVPD FT GIRALRERGFRLVTMTNGSSDLSKRLLGRAGLADCFESHLDASGPQRWKPAQAAYQYVV FT EQVGVRLDEAVLVAVHPWDVDGAQRAGLGGAWLRRDAADYPQVMLPPTYTVGNLRELAE FT TLA" FT misc_feature complement(183560..184141) FT /note="Pfam match to entry PF00702 Hydrolase, haloacid FT dehalogenase-like hydrolase, score 26.60, E-value 3.3e-05" FT RBS complement(184162..184165) FT CDS complement(184297..184980) FT /transl_table=11 FT /gene="SCO3447" FT /gene_synonym="SCE46.04c" FT /product="putative transcriptional regulatory protein" FT /note="SCE46.04c, possible transcriptional regulatory FT protein, len: 227 aa; similar to TR:O53922 (EMBL:AL022002) FT Mycobacterium tuberculosis hypothetical 26.8kD protein FT MTV047.10c, 244 aa; fasta scores: opt: 486 z-score: 603.1 FT E(): 3e-26; 40.5% identity in 220 aa overlap. Contains Pfam FT matches to entries PF00325 crp, Bacterial regulatory FT proteins, crp family and PF00027 cNMP_binding, Cyclic FT nucleotide-binding domain. Contains a possible FT helix-turn-helix motif at residues 176..197 (+4.24 SD)" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9RKI5" FT /protein_id="CAB61855.1" FT /translation="MTVVGPAAQRTAAWIAGCMRSFLPPGHIDALKLADRLEHRQLRQG FT QIIFTQGTHPDGVWMVRSGELELVAGRGQDRVVVGTLQPCGIAGDVPLLLGKPAVCTVR FT ARTDVQSSFLSAAGFFATLDASPALTRAWLTALAHRHLRAQEAQVRTLQGSAESRAAWL FT LLREARDSAVTCSQGTLAAMLGMRRQTMNRVIKDFERQGLLRVGYCRLELLAVDRLRQR FT AQDRA" FT misc_feature complement(184369..184464) FT /note="Pfam match to entry PF00325 crp, Bacterial FT regulatory proteins, crp family, score 17.70, E-value FT 0.00032" FT misc_feature complement(184597..184875) FT /note="Pfam match to entry PF00027 cNMP_binding, Cyclic FT nucleotide-binding domain, score 48.00, E-value 2.1e-10" FT CDS complement(185009..185311) FT /transl_table=11 FT /gene="SCO3448" FT /gene_synonym="SCE46.05c" FT /product="hypothetical protein SCE46.05c" FT /note="SCE46.05c, unknown, len: 100 aa" FT /db_xref="UniProtKB/TrEMBL:Q9RKI4" FT /protein_id="CAB61856.1" FT /translation="MPVTVAVVAALAPVVRGHRSGRSPVLRAADEVPGAPMTAPAASRV FT VAVPRVARRRRRFRIRDASLDSAGRRLPPCTATCTFRDRRPTAEPARQAKAWSGR" FT CDS complement(185402..185722) FT /transl_table=11 FT /gene="SCO3449" FT /gene_synonym="SCE46.06c" FT /product="hypothetical protein SCE46.06c" FT /note="SCE46.06c, unknown, len: 106 aa" FT /db_xref="UniProtKB/TrEMBL:Q9RKI3" FT /protein_id="CAB61857.1" FT /translation="MKRPWQRRPAVERRMNCMQVGRVLQSYLDGETDEVTARRVAAHLE FT DCRRCGLEASVYRELHDALARRAEPDGGAVERLRAFGASLMSDPPAGDDDAEHGTTPPA FT GA" FT CDS complement(185719..186324) FT /transl_table=11 FT /gene="SCO3450" FT /gene_synonym="SCE46.07c" FT /product="putative RNA polymerase sigma factor (ECF FT subfamily)" FT /note="SCE46.07c, probable RNA polymerase sigma factor (ECF FT subfamily), len: 201 aa; similar to TR:O87834 FT (EMBL:AJ010320) Streptomyces coelicolor RNA polymerase FT sigma factor SigR, 227 aa; fasta scores: opt: 337 z-score: FT 413.7 E(): 1.1e-15; 34.1% identity in 208 aa overlap and to FT SW:RPOE_MYCTU (EMBL:Z95120) Mycobacterium tuberculosis RNA FT polymerase sigma-E factor (sigma-24), 216 aa; fasta socres: FT opt: 339 z-score: 416.4 E(): 7.5e-16; 35.4% identity in 189 FT aa overlap. Contains match to Pfam entry PF00776 FT Sigma70_ECF, Sigma-70 factor (ECF subfamily) and match to FT PS01063 Sigma-70 factors ECF subfamily signature. Contains FT also a possible helix-turn-helix motif at residues 159..180 FT (+3.23 SD)" FT /db_xref="GOA:Q9RKI2" FT /db_xref="HSSP:1H3L" FT /db_xref="InterPro:IPR007630" FT /db_xref="UniProtKB/TrEMBL:Q9RKI2" FT /protein_id="CAB61858.1" FT /translation="MECGSGRGGFRRVEDEVTAPPDSADPRGQAFAAYVLPEVEVLLRV FT AMTLTAQPADAEDLVQDTLLRAYRAIDRFDGKHPRAWLLTIMRRAEINRHRRRRPHLLD FT DPDADLDRLSSTGPSGSAEEIVVGEAFDEVVDEALGALPDKHRQVVQLVDIDGLTYAEA FT AHLLDVPEGTVMSRLHRARKRIRARLATAGLAPKRGVM" FT RBS complement(185729..185732) FT misc_feature complement(186001..186195) FT /note="Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 FT factor (ECF subfamily), score 53.40, E-value 4.9e-12" FT misc_feature complement(186067..186159) FT /note="PS01063 Sigma-70 factors ECF subfamily signature" FT RBS 186425..186430 FT CDS 186442..186753 FT /transl_table=11 FT /gene="SCO3451" FT /gene_synonym="SCE46.08" FT /product="hypothetical protein SCE46.08" FT /note="SCE46.08, unknown, len: 103 aa" FT /db_xref="UniProtKB/TrEMBL:Q9RKI1" FT /protein_id="CAB61859.1" FT /translation="MKKQRVPGPGRVWAECREKIRHIRLRGEVEAYADGQLTGAHRMQV FT AAHIACCWACSGSLQLLRLIKASLRHSPQRTPPSLASARVRRFAQDLSAPTGRDRPSG" FT CDS complement(186816..187895) FT /transl_table=11 FT /gene="SCO3452" FT /gene_synonym="SCE46.09c" FT /product="putative methyltransferase" FT /note="SCE46.09c, probable methyltransferase, len: 359 aa; FT similar to TR:AAF00618 (EMBL:AF166383) Mus musculus FT methyltransferase, 336 aa; fasta scores: opt: 868 z-score: FT 1022.0 E(): 0; 44.7% identity in 320 aa overlap and to FT SW:GRC2_LACLA (EMBL:L14679) Lactococcus lactis probable FT menaquinone biosynthesis methyltransferase (EC 2.1.1.-), FT 252 aa; fasta scores: opt: 221 z-score: 265.2 E(): 2e-07; FT 38.7% identity in 111 aa overlap. Contains Pfam match to FT entry PF01209 Ubie_methyltran, ubiE/COQ5 methyltransferase FT family" FT /db_xref="GOA:Q9RKI0" FT /db_xref="HSSP:1UFK" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:Q9RKI0" FT /protein_id="CAB61860.1" FT /translation="MATTDVSTDQQAAEASVAQSVRDYYGKVLASSADLKTTACCTDVA FT PPPHIAAALAEVHDEVMERFYGCGSPIPPALEGATVLDLGSGSGRDVYVLSQLVGPTGR FT VIGVDMTEEQLAVARRHQDWHAERFGHANTDFRHGYIEDLAGAGIPDASVDVVVSNCVV FT NLSPDKPRVLSEIFRVLKPGGELYFSDIFSDRRLPASLLDDPVLVGECLAGALYTEDFR FT RALERVGCPDARTLAASPVTISDPDIEVKIGFATFTSRTIRAFKLPLEDRCEDYGQVAV FT YHGTIAEHPHAFDLDDHHRLHTGKPALVCGNTADMLAATRYAAHFTVTGDKSQHFGLFP FT CTPAEGAAAPGLGAAPGCC" FT misc_feature complement(187098..187790) FT /note="Pfam match to entry PF01209 Ubie_methyltran, FT ubiE/COQ5 methyltransferase family, score -97.80, E-value FT 8.1e-05" FT RBS complement(187898..187903) FT CDS complement(188011..189075) FT /transl_table=11 FT /gene="SCO3453" FT /gene_synonym="SCE46.10c" FT /product="putative ABC-transporter ATP binding protein" FT /note="SCE46.10c, probable ABC-transporter ATP binding FT protein, len: 354 aa; similar to TR:CAB49712 FT (EMBL:AJ248285) Pyrococcus abyssi ABC-transporter ATP FT binding protein, 329 aa; fasta scores opt: 708 z-score: FT 742.4 E(): 0; 43.9% identity in 280 aa overlap and to FT SW:CYSA_ECOLI (EMBL:M32101) Escherichia coli sulfate FT transport ATP-binding protein CysA, 365 aa; fasta scores: FT opt: 668 z-score: 700.3 E(): 1.2e-31; 38.6% identity in 332 FT aa overlap. Contains Pfam match to entry PF00005 ABC_tran, FT ABC transporter and two matches to Prosite entries PS00211 FT ABC transporters family signature and PS00017 FT ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9RKH9" FT /db_xref="HSSP:1G29" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9RKH9" FT /protein_id="CAB61861.1" FT /translation="MTPLSSTPAPGLRLEQITVTYPGHREPVLDGLDLDVADGRLLALL FT GPSGCGKTTTVQVASGLLTPGRGAVHLRGTEVTRVPPEHRGAAVVFQQPMLLPHRTALD FT NVAFPARMRGRSRRDARTSALAHLERVGLGALAARYPRQLSGGQAQRVALARALAAEPA FT VLLLDEPFSALDPSLRHTMRDLLTTVQRELAVTTVLVTHDQTEAASVADTIALLDRGGL FT LQQAQPADLYARPASLAVAHFLGCPTALPGHVTPQGRFACPLGELDLPDTVTHRGPGHL FT VIRPEAVQLGTGPDTVAAVVHSVRPEGAFTALVADTAAGPVHVLLPPGTPPAPSEHVRL FT HLPVAHRWVVPRLG" FT misc_feature complement(188416..188961) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 206.00, E-value 5.8e-58" FT misc_feature complement(188602..188646) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(188917..188940) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(189081..189923) FT /transl_table=11 FT /gene="SCO3454" FT /gene_synonym="SCE46.11c" FT /product="putative ABC-transporter membrane protein" FT /note="SCE46.11c, possible ABC-transporter membrane FT protein, len: 280 aa; similar to TR:Q44381 (EMBL:U60011) FT Agrobacterium tumefaciens inner membrane protein MotD, 273 FT aa; fasta scores: opt: 360 z-score: 418.0 E(): 6.1e-16; FT 29.3% identity in 256 aa overlap and to SW:POTC_ECOLI FT (EMBL:M64519) Escherichia coli spermidine/putrescine FT transport system permease protein PotC, 264 aa; fasta FT scores: opt: 309 z-score: 360.4 E(): 1e-12; 25.8% identity FT in 260 aa overlap. Contains Pfam match to entry PF00528 FT BPD_transp, Binding-protein-dependent transport systems FT inner membrane component and Prosite match to entry PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign. and possible N-terminal region signal peptide FT sequence. Contains also a possible helix-turn-helix motif FT at residues 159..180 (+3.23 SD)" FT /db_xref="GOA:Q9RKH8" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9RKH8" FT /protein_id="CAB61862.1" FT /translation="MRRALHSAGFAMLTLWIAAPLLPLLIWAFAGRWVYPALVPQDFTL FT RAWDQAAAPQQQVLAATGTSLGLALTTAVTATVLGALAARGLVLYRPPAAGLVRLLLLA FT PVLVPPFALAVGVQEVFVRVGLSDQSAGVALVHLVPALPYTVLVMIGGYATYDVRMEQT FT ARTLGASRSAVLRHVTLPALAPALLASATLAFLVSWSEYLMTVLVGGGVVTTLPLLLFS FT TAAGSGNQALTAVLGILTVVPPILLFGVGAALLRRHRAVWADPDPASSSSSAAPGIER" FT misc_feature complement(189249..189470) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 39.50, E-value 7.7e-08" FT misc_feature complement(189381..189467) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS complement(189920..190777) FT /transl_table=11 FT /gene="SCO3455" FT /gene_synonym="SCE46.12c" FT /product="putative ABC-transporter transport protein" FT /note="SCE46.12c, possible ABC-transporter transport FT protein, len: 285 aa; similar to TR:O57756 (EMBL:AP000001) FT Pyrococcus horikoshii 284 aa long hypothetical sugar FT transport membrane protein, 284 aa; fasta scores: opt: 281 FT z-score: 329.5 E(): 5.2e-11; 26.6% identity in 278 aa FT overlap and to SW:UGPA_ECOLI (EMBL:X13141) Escherichia coli FT SN-glycerol-3-phosphate transport system permease protein FT UgpA, 295 aa; fasta scores: opt: 233 z-score: 274.6 E(): FT 6e-08; 28.7% identity in 279 aa overlap. Contains Pfam FT match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component. Contains possible N-terminal region signal FT peptide sequence" FT /db_xref="GOA:Q9RKH7" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9RKH7" FT /protein_id="CAB61863.1" FT /translation="MPPRWRGLLLTAPALAVVAFAGGALLLAARGSLADGLGRGWSLSA FT YAGLLQDPAFADSLLLSLKIATLSTVMSAALALAVVGAVSGSRRGRAALETAARATLAV FT PHLLAAAAFALLLSGSGLISRLTHAAGWTDGPADFPALVAGTTPSAVVLTYVWKEAPFV FT TIMLLAAYTPAVRDLENAIRTLGAGRMRRMRHVTLPLLAPALTEACLLVFAFTFAAYEA FT PALLGATVPRALPVEAVELYRSVELADRPAALALAVVIGMVIALAALAAAAISRRLLLA FT RTGP" FT misc_feature complement(190049..190210) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 33.00, E-value 6.7e-06" FT CDS complement(190786..192039) FT /transl_table=11 FT /gene="SCO3456" FT /gene_synonym="SCE46.13c" FT /product="putative secreted protein" FT /note="SCE46.13c, possible secreted protein, len: 135 aa; FT similar to TR:CAC41457 (EMBL:AL591782) Rhizobium meliloti FT conserved hypothetical protein SMC02589, 408 aa; fasta FT scores: opt: 927 Z-score: 1029.9 E(): 9.8e-50; 37.198% FT identity in 414 aa overlap. Contains possible N-terminal FT region signal peptide sequence" FT /db_xref="GOA:Q9RKH6" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:Q9RKH6" FT /protein_id="CAB61864.1" FT /translation="MRHSGRRVKRATVLAAGAAVAGLLTAACSSPDTTGVEPPAKDWAQ FT LRADAKGQSVNLFMYGGDKGANAYIDDEVAPTAKKLGITVKRVPVADTQDAVQKILGDQ FT RAGKGSGGAVDLVWVNGENFRTGKQADLWLCGYTGLMPNQKYLDSTDPTLTQDFGTPVD FT DCETPWSRAQFAFVYDSAKLADPPRTTAALTEWIKQNPGRFTYPAPPDFTGSAFVRQIL FT LARAQDEPVPPAYSKKAYETVAPGLWKDLNALKPALWRQGATYPKDQAALNDLFANGEV FT DMTMTYGPAEVPALVDKGQFPPSTRVFVPEDGTLGNTSYLAVPKNAAHREAALVLSDLM FT LSPELQYAKARPGGWGAYTVLDQERLPEQWREKFASLTTPETTLPIEELSRNARPELSG FT DWVGPLDKGWKQEVASAP" FT misc_feature complement(191956..191988) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS 192192..192196 FT CDS 192203..192820 FT /transl_table=11 FT /gene="SCO3457" FT /gene_synonym="SCE46.14" FT /product="putative transmembrane protein" FT /note="SCE46.14, possible transmembrane protein, len: 205 FT aa; similar to TR:P76226 (EMBL:AE000270) Escherichia coli FT from bases 1830199 to 1840304, 208 aa; fasta scores: opt: FT 402 z-score: 471.0 E(): 6.9e-19; 37.4% identity in 206 aa FT overlap and to TR:CAB50482 (EMBL:AJ248288) Pyrococcus FT abyssi predicted CDP-diacylglycerol-glycerol-3-phosphate FT 3-phosphatidyltransferase PgsA, 185 aa; fasta scores: opt: FT 216 z-score: 259.1 E(): 4.4e-07; 31.2% identity in 205 aa FT overlap" FT /db_xref="GOA:Q9RKH5" FT /db_xref="InterPro:IPR000462" FT /db_xref="UniProtKB/TrEMBL:Q9RKH5" FT /protein_id="CAB61865.1" FT /translation="MLDVRARAALSGPLDRAAAMLDRPAVTPNRLTALGLLTGLASAGS FT AAAGWWPAAAALWLLSRLADGLDGPLARRRGTANSSGAGGFLDISADFLVYGAFVVGVA FT VGVGGPALPFLLVLLTYYVNGTAFLAFSSIAERTGRRGDGRLSGGRSLNFLGGLAEGGE FT TIAVHTLWCLLPGFAHTIAWVWAAVVAVTAAHRVVTGYRQLR" FT CDS complement(192795..193544) FT /transl_table=11 FT /gene="SCO3458" FT /gene_synonym="SCE46.15c" FT /product="putative integral membrane protein" FT /note="SCE46.15c possible integral membrane protein, len: FT 249 aa; similar to various hypothetical proteins, e.g. FT SW:Y305_SYNY3 (EMBL:D64005) Synechocystis sp. hypothetical FT 22.2 kD protein SLR0305, 209 aa; fasta scores: opt: 419 FT z-score: 450.0 E(): 1e-17; 39.8% identity in 161 aa FT overlap" FT /db_xref="InterPro:IPR015414" FT /db_xref="UniProtKB/TrEMBL:Q9RKH4" FT /protein_id="CAB61866.1" FT /translation="MNRPAASSSATELPPPSTDPDEERRRPARAAWIRLAFLVALLLAL FT GSWVALGGGDLLRDVRQWVDSLGVWGPVVFAVVYALAVTALLPGSVLTASAGALFGLAV FT GAGAVLVGATAGAALSFGLARWLGRPVVARYAGSGRLARLDAFLTRRGFVAVLLVRLVP FT LFPFSVINYGAGVAGVRFSSYVAATALGIIPGTLVYTGLGGSLGDPGSPGLWIALGALL FT VLSAGGWWAARLLRSRGAGVSAAADSR" FT CDS complement(193541..194404) FT /transl_table=11 FT /gene="SCO3459" FT /gene_synonym="SCE46.16c" FT /product="hypothetical potein SCE46.16c" FT /note="SCE46.16c, hypothetical protein, len: 287 aa; FT similar to various hypothetical proteins, e.g. TR:CAB52055 FT (EMBL:AL109732) Streptomyces coelicolor hypothetical 24.3kD FT protein; fasta scores: opt: 165 z-score: 195.9 E(): 0.0014; FT 37.4% identity in 131 aa overlap" FT /db_xref="GOA:Q9RKH3" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:Q9RKH3" FT /protein_id="CAB61867.1" FT /translation="MRDQPGRVPEGSTGARAASMSHRRGEGWMDEPDWRRFITAYHQEH FT AGITEQLFSLADTSPYAWLAEPLRAVEGTVLDLACGSAPTRQELPDADWVGVDLSAAEL FT AEAARQGRGPLLRAAADALPAASASVGAVCAAMCLPVVTPLPQTLGEIRRVLRPGGVLA FT ALVPSQSGLSPSGMLGWVRVMAALRAVRQPWPNPQARDGLPALLRTAGFRVRRDERHVF FT TLAIDSAGAAALLADALYLPGLTTHRAQAAKRSLARWATPGRRLELPLRRVVAELPIEQ FT QSQETT" FT RBS complement(193549..193553) FT CDS 194465..195982 FT /transl_table=11 FT /gene="SCO3460" FT /gene_synonym="SCE46.17" FT /product="putative oxidoreductase" FT /note="SCE46.17, probable oxidoreductase, len: 505 aa; FT similar to SW:MERA_STAAU (EMBL:L29436) Staphylococcus FT aureus mercuric reductase (EC 1.16.1.1) MerA, 547 aa; fasta FT scores: opt: 891 z-score: 971.7 E(): 0; 37.4% identity in FT 452 aa overlap. Contains match to Prosite entry PS00076 FT Pyridine nucleotide-disulphide oxidoreductases class-I FT active site" FT /db_xref="GOA:Q9RKH2" FT /db_xref="HSSP:1ONF" FT /db_xref="InterPro:IPR000815" FT /db_xref="UniProtKB/TrEMBL:Q9RKH2" FT /protein_id="CAB61868.1" FT /translation="MEAGKGRNRLRQRVPLPSHARAPAIPRRRTDREFRAMKRYDLVVI FT GGGSAGLTAARTAGRLGARTLLVERDRLGGDCLWTGCVPSKALLHVAADVQAARRATAY FT GLPPVTGPADLTAALAEVKRAIGAIEPHDSAEALAPYGVDVTHGAASFTGPGTLTAGER FT EVSFRYALIATGSSPALVPIPGLVESGPLTSDTVWELSELPHLLVVLGGGPIGCELGQA FT FARLGSQVTLVEAMDRLVPREEPRASQVLRERLQSEGVTVLTDYRAERVDADAVHGPGG FT PLPYDALLAVTGRRSHTHGLGLEAAGVELTDAGHIRTDGRLRTTNHRIYAAGDVTGRSA FT FTHLGGTQGGAAAVDALLGVRRPIDYRAAPRVTYTDPEIAGVGLTLDEAHAKYGDRARV FT HTLENDRVDRAVADGRTEGFTTLVLGPRGKIVGATVVSPRAGETVAHLAAAVRLGWTPS FT DYARTVHPYPTYADGPWHTALTDVYARLARGSGPIGALLKLRRGVIR" FT misc_feature 194684..194716 FT /note="PS00076 Pyridine nucleotide-disulphide FT oxidoreductases class-I active site" FT RBS 195966..195971 FT CDS 195979..196437 FT /transl_table=11 FT /gene="SCO3461" FT /gene_synonym="SCE46.18" FT /product="putative integral membrane protein" FT /note="SCE46.18, possible integral membrane protein, len: FT 152 aa; similar to SW: MAUE_PARDE (EMBL:X98581) Paracoccus FT denitrificans methylamine utilization protein MauE, 186 aa; FT fasta scores: opt: 162 z-score: 208.6 E(): 0.00028; 28.1% FT identity in 139 aa overlap. Contains possible N-terminal FT region signal peptide sequence" FT /db_xref="UniProtKB/TrEMBL:Q9RKH1" FT /protein_id="CAB61869.1" FT /translation="MILRLVLGLLLAAMALGQAASFDAMPAILTAYGLTSGAVSTALAV FT ALISAEAVTALWFLARPRSRATTPVWLYTAVAVAWSVPASQAFARGLVLDNCGCFGTYL FT AQPLRWYVLVEDALMLLYAGLLWRGLRRARPTSSPATARTDRTPQENP" FT RBS 196425..196429 FT CDS 196437..197873 FT /transl_table=11 FT /gene="SCO3462" FT /gene_synonym="SCE46.19" FT /product="hypothetical protein SCE46.19" FT /note="SCE46.19, unknown, len: 478 aa" FT /db_xref="GOA:Q9RKH0" FT /db_xref="InterPro:IPR007197" FT /db_xref="UniProtKB/TrEMBL:Q9RKH0" FT /protein_id="CAB61870.1" FT /translation="MRITAKLRALERATRPYDTAFAAAMERRWKELPDTAKTPGQILGR FT HGVGCEGTHGVFPKCNLKCTPCYHSRDANQVRVDGPHTHEQITAQMRLLRELRGPRAHT FT QLIGGEVSLLTPDDHAAALAIMRDHGREPMSFTHGDFDDDYLTRLALGPDDTRRFGRLS FT FAAHFDKFMYGRRGIERPPDEQSLNPYRARFAAMFRRLRREHGVRSFLAHNMTVTPGNL FT DEVAAVIRDCHAMGYGMFSFQPAAFLGDDRRWKEKFREATPDAVWAEIERGAGTRLDYR FT VFENGDVRCNRTAYGFYVGHRWYPFLDGDDPRDLAVRDAFFRYFGKMTFTGTPPALLAA FT RITRVVARHPSTAVTAFRWLARTIRRVGLLRLVRHRMRVRTVTFVMHQFMDADVVAPAW FT EMMQRGEQAEEPRLRETQERLAACHYAMAHPENGTLVPACVQHAVLDPAENAALRTLLP FT FVEVRTPTRRSPGTSGTSDR" FT RBS 197887..197891 FT CDS 197900..198688 FT /transl_table=11 FT /gene="SCO3463" FT /gene_synonym="SCE46.20" FT /product="putative phosphorylase" FT /note="SCE46.20, probable phosphorylase, len: 262 aa; FT similar to TR:O58891 (EMBL:AP000005) Pyrococcus horikoshii FT 265 aa long hypothetical 5'-methylthioadenosine FT phosphorylase PH1143 265 aa; fasta scores: opt: 461 FT z-score: 534.1 E(): 2.1e-22; 35.1% identity in 251 aa FT overlap and to SW:MTAP_HUMAN (EMBL:U22233) Homo sapiens FT 5'-methylthioadenosine phosphorylase (EC 2.4.2.28) MtaP, FT 283 aa; fasta scores: opt: 373 z-score: 433.4 E(): 8.6e-17; FT 32.4% identity in 216 aa overlap. Contains Pfam match to FT entry PF00896 Mtap_PNP, phosphorylases family 2" FT /db_xref="GOA:Q9RKG9" FT /db_xref="HSSP:1CB0" FT /db_xref="InterPro:IPR001369" FT /db_xref="UniProtKB/TrEMBL:Q9RKG9" FT /protein_id="CAB61871.1" FT /translation="MRIGVITGSGSYDWPHLEGAAERTVVTEHGAVTVTEGRLGGAEIV FT QLSRHGTGHHRLSSQVDHKANLAALLAVEAEAVVSFTVCGSLEPDVRPGSLVVFDDLYF FT PANRLPDGTPCTWYDTPGGAGRGHWIFDRPFSEPLRQALITAADQTGVPVATQGVYGHV FT DGPRFNTRPEVAALAAAGVSAISQTAGPEVVLAGEAELPMVLVGFVTDYANGVAPEPEP FT VQALLDRMAASKDVFAKLAEHALPSLSAVSGAGFVYRFDT" FT misc_feature 197906..198532 FT /note="Pfam match to entry PF00896 Mtap_PNP, phosphorylases FT family 2, score 79.60, E-value 6.2e-20" FT CDS 198727..199359 FT /transl_table=11 FT /gene="SCO3464" FT /gene_synonym="SCE46.21" FT /product="conserved hypothetical protein SCE46.21" FT /note="SCE46.21, hypothetical protein, len: 210 aa; FT identical to N-terminal region of previously sequenced FT TR:BAA84086 (EMBL:AB032065) Streptomyces coelicolor FT hypothetical 47.9 kD protein, 446 aa and similar to FT TR:P74231 (EMBL:D90913) Synechocystis sp. (strain PCC 6803) FT hypothetical 23.5 kD protein, 211 aa; fasta scores: opt: FT 327 z-score: 394.6 E(): 1.2e-14; 36.5% identity in 189 aa FT overlap. Contains plasmid SCP1 integration target site" FT /db_xref="InterPro:IPR018641" FT /db_xref="UniProtKB/TrEMBL:Q9RKG8" FT /protein_id="CAB61872.1" FT /translation="MAKAPRPGTVKTRLHPLLGPQRCAKLQAELIRHTMAVTTAHTPSA FT YLAYAPNDGKDAISTAVPAGVRLLRQCGEDLGQRLAAAVTDAFTDGAGPLLVIGTDAPT FT LTADHLSAAFTALEHHDVTLGPALDGGYYLIGLRAPHTSLFALAPDVWSTDRVLAATRA FT LADGEGLSTGMLRPLRDLDTPEDAAALLTDPALPTPIAALLQPKEKP" FT misc_feature 199122..199181 FT /note="plasmid SCP1 integration target site [Streptomyces FT coelicolor, strain M130, Genomic, 60 nt] (EMBL:S38799)" FT RBS 199347..199351 FT CDS 199356..200066 FT /transl_table=11 FT /gene="SCO3465" FT /gene_synonym="SCE65.01" FT /gene_synonym="SCE46.22" FT /product="hypothetical protein" FT /note="SCE65.01, hypothetical protein (partial CDS), len: FT >38 aa; identical to previously sequenced TR:BAA84086 FT (EMBL:AB032065) Streptomyces ceolicolor hypothetical 47.9 FT KD protein, 446 aa" FT /note="SCE46.22, hypothetical protein, len: >231 aa; FT identical to C-terminal region of previously sequenced FT TR:BAA84086 (EMBL:AB032065) Streptomyces coelicolor FT hypothetical 47.9 kD protein, 446 aa. Contains Pfam match FT to entry PF00535 Glycos_transf_2, Glycosyl transferases" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q8CJW5" FT /protein_id="CAD55319.1" FT /translation="MTQVSIIVPVLNEESTIHSAVSRLCRDFPDCELIVVDGGSTDATA FT ELAALHATVIGSERGRAKQMNEGARHASGGILWFIHADTAIEPEALGQIRSVLADPAVV FT AGGLTLRFDRRTPALNYLAWTSNARARRLHHIFGDQAMFIRRTAFDELGGFPDLAIMED FT LEMSRRLHRRGPLRLLPATSTASSRRLTAHGTWRMIAFMQYLKLLYFAGADPEAIRARY FT TAGPRLFPKRNPAT" FT misc_feature 199368..199814 FT /note="Pfam match to entry PF00535 Glycos_transf_2, FT Glycosyl transferases, score 58.60, E-value 1.3e-13" FT misc_feature 199949..204056 FT /note="previosuly sequenced fragment (EMBL:AJ245804) 100% FT identity" FT repeat_region 200185..200207 FT /note="23 bp IR for IS648" FT repeat_region 200185..201309 FT /note="IS468" FT CDS 200421..201260 FT /transl_table=11 FT /gene="SCO3466" FT /gene_synonym="IS468B" FT /gene_synonym="SCE65.02" FT /product="transposase" FT /note="SCE65.02, IS468B, transposase, len: 279 aa; FT identical to previously sequenced TR:BAA84088 FT (EMB:AB032065) Streptomyces coelicolor transposase FT IS468B-ORF, to Streptomyces coelicolor SCE65.03 and to FT Streptomyces coelicolor SCJ11.27c. Contains Pfam matches to FT entry PF01675 Transposase_13, Transposase and to entry FT PF01511 Transposase_6, Transposase" FT /db_xref="GOA:Q9Z9H3" FT /db_xref="InterPro:IPR002559" FT /db_xref="UniProtKB/TrEMBL:Q9Z9H3" FT /protein_id="CAB61790.1" FT /translation="MSERKPYPSDLSDARWALIEPTLTAWRNARLERRPTGKPAQVDLR FT DVFNAILYLNRTGIPWKYLPHDFPGHGTVYFYYAAWRDEGIFTQLNYDLTALARVKEGR FT KPEPTASVIDTQSVKTSTNVPLTSQGTDAAKKIVGRKRGILTDTIGLILAVTVTGAGLS FT ENAVGIRLLDQAKRTYPTIVKSWVDTGFKNAVIEHGATLGIDVEVVNRNPEKRGFHVVK FT RRWVVERSIGWIMMHRRLARDYETLTTSSEAMIHIASIDNLAKRITDETTPTWRGTY" FT misc_feature 200562..200816 FT /note="Pfam match to entry PF01511 Transposase_6, FT Transposase, score 106.60, E-value 4.9e-28" FT misc_feature 200946..201194 FT /note="Pfam match to entry PF01675 Transposase_13, FT Transposase, score 83.30, E-value 5e-21" FT repeat_region complement(201287..201309) FT /note="23 bp IR for IS648" FT CDS 201523..202362 FT /transl_table=11 FT /gene="SCO3467" FT /gene_synonym="IS468B" FT /gene_synonym="SCE65.03" FT /product="transposase" FT /note="SCE65.03, IS468B, transposase, len: 279 aa; FT identical to previously sequenced TR:BAA84088 FT (EMB:AB032065) Streptomyces coelicolor transposase FT IS468B-ORF, to S. coelicolor SCE65.02 and to S. coelicolor FT SCJ11.27c. Contains Pfam matches to entry PF01675 FT Transposase_13, Transposase and to entry PF01511 FT Transposase_6, Transposase" FT /db_xref="GOA:Q9Z9H3" FT /db_xref="InterPro:IPR002559" FT /db_xref="UniProtKB/TrEMBL:Q9Z9H3" FT /protein_id="CAB61791.1" FT /translation="MSERKPYPSDLSDARWALIEPTLTAWRNARLERRPTGKPAQVDLR FT DVFNAILYLNRTGIPWKYLPHDFPGHGTVYFYYAAWRDEGIFTQLNYDLTALARVKEGR FT KPEPTASVIDTQSVKTSTNVPLTSQGTDAAKKIVGRKRGILTDTIGLILAVTVTGAGLS FT ENAVGIRLLDQAKRTYPTIVKSWVDTGFKNAVIEHGATLGIDVEVVNRNPEKRGFHVVK FT RRWVVERSIGWIMMHRRLARDYETLTTSSEAMIHIASIDNLAKRITDETTPTWRGTY" FT misc_feature 201664..201918 FT /note="Pfam match to entry PF01511 Transposase_6, FT Transposase, score 106.60, E-value 4.9e-28" FT misc_feature 202048..202296 FT /note="Pfam match to entry PF01675 Transposase_13, FT Transposase, score 83.30, E-value 5e-21" FT repeat_region 202414..202449 FT /note="36 bp IR for IS469" FT repeat_region 202414..204082 FT /note="IS469" FT CDS 202507..204012 FT /transl_table=11 FT /gene="SCO3468" FT /gene_synonym="IS469" FT /gene_synonym="SCE65.04" FT /product="transposase" FT /note="SCE65.04, IS469, transposase, len: 501 a; identical FT to previously sequenced TR:BAA84089 (EMBL:AB032065) FT Streptomyces coelicolor IS469-ORF, 501 aa, to Streptomyces FT coelicolor SCE65.26 and highly similar to Streptomyces FT coelicolor SCE65.05c, 513 aa; fasta scores: opt: 2079 FT z-score: 2166.3 E(): 0; 63.7% identity in 501 aa overlap. FT Contains Leucine TTA codon, possible target for bldA FT regulation" FT /db_xref="GOA:Q9R2U8" FT /db_xref="InterPro:IPR002560" FT /db_xref="UniProtKB/TrEMBL:Q9R2U8" FT /protein_id="CAB61792.1" FT /translation="MFSGLSALVIEEVADDGEVIRVAARTRDVPSPCPVCGVLTGKVHG FT YHGRPMADVPVDGRKVVVHVQVRRLVCPVLECRRQTFREQVPGLMERLQRRTNRLTSQV FT SAVVKELCGRAAARLSRSLAVPMSFATALRLLRRIPIPVVRTPRVVGVDDFALRRRHRY FT ATIIIDAETGERIDVLPGREAAGLEAWLLEHPGVETVCRDGSATYAEAIRRALPDAVQV FT SDRWHLWRNLCDKVLAEVRAHASCWATVNPARPGGVHEQTIRERWHQIHDLLGRGVGLL FT ECSRRLDLALNTVKRYSRIPEPPADRIAPRYRTTLVDPYREHLRIRRATEPAVAVTQLF FT HEIKAQGYTGSHNLLVRYLTQGRAEGNRPVITPRHATRLLLTHPEHLWTKDTALLATLT FT SACPETAELAKFVGTFAQLLTPEKGNDARLTEWIADVRAADLPHLHSFCNGLELDRAAV FT NAGLTLPHHNGRTEGVNTRTKRIMRQMHGRAGFDLLRHRILLS" FT misc_feature 202837..202839 FT /gene="none" FT /note="Leucine TTA codon. Possible target for bldA FT regulation" FT repeat_region complement(204049..204082) FT /note="34 bp repeat for IS469" FT repeat_region complement(204049..205690) FT /note="IS469" FT misc_feature complement(204049..206575) FT /note="previously sequenced fragment (EMBL:AB032065)" FT CDS complement(204093..205634) FT /transl_table=11 FT /gene="SCO3469" FT /gene_synonym="IS469" FT /gene_synonym="SCE65.05c" FT /product="transposase" FT /note="SCE65.05c, IS469, transposase, len: 513 aa; FT identical to previously sequenced TR:BAA84089 FT (EMBL:AB032065) Streptomyces coelicolor IS469-ORF, 501 aa, FT to Streptomyces coelicolor SCE65.26 and highly similar to FT Streptomyces coelicolor SCE65.04, 501 aa; fasta scores: FT opt: 2079 z-score: 2040.2 E(): 0; 63.7% identity in 501 aa FT overlap. Contains Pfam match to entry PF01610 FT Transposase_12, Transposase. Also contains Leucine TTA FT codon, possible target for bldA regulation and a possible FT helix-turn-helix motif at residues 219..312 (+3.15 SD)" FT /db_xref="GOA:Q9R2U5" FT /db_xref="InterPro:IPR017894" FT /db_xref="UniProtKB/TrEMBL:Q9R2U5" FT /protein_id="CAB61793.1" FT /translation="MSVESLNELVATAFSGISPLVIEDVVDEGERVVVRARTPGSTAVC FT PACGALSERVHGYHWRTVADLPIDGRRVVVRVRVRRLVCPTRGCRHTFREQLPGVLERY FT QRRTARLTRQIKAVVKELAGRAGSRLLAKLAIGLSRHTALRTLLRIALPTGRVPRVIGV FT DDFALRRRHRYATVVIDAETHERIDVLPDRTADTLEAWLRENPGVEVVCRDGSATYAEA FT IRRALPDAVQVTDRWHLWHNLCETALSEVKAHSTCWAAVLDTPIYEGPRAQTTLERWHQ FT VHGLLQQRVSLLECARRLQLSLNTVKRYARADRPERMLRVPKYRASLVDPYRDHLRRRR FT AEDPAVPVQHLFEEIKALGFTGCLNLLHKYINQGRADADRSHISPRRLARMLLTRPENL FT KSGHRDLLDQLTAACPEMTHLATSVRTFAQLLKPRPENVDALDHWITQVRAADLPHLHA FT FTRGLERDNDAVIAALTLPYSNGPTEGVNTKTKRIARQMHGRAGFNLLRHRILLG" FT misc_feature complement(204597..205538) FT /note="Pfam match to entry PF01610 Transposase_12, FT Transposase, score 58.60, E-value 1.4e-13" FT misc_feature complement(205269..205271) FT /gene="none" FT /note="Leucine TTA codon. Possible target for bldA FT regulation" FT repeat_region complement(205657..205690) FT /note="34 bp repeat for IS469" FT CDS complement(205748..206575) FT /transl_table=11 FT /gene="SCO3470" FT /gene_synonym="IS470" FT /gene_synonym="SCE65.06c" FT /product="transposase" FT /note="SCE65.06c, IS470, transposase, len: 275 aa; FT identical to previously sequenced TR:BAA84091 FT (EMBL:AB032065) Streptomyces coelicolor transposase FT IS470-ORF, 275 aa" FT /db_xref="GOA:Q9R319" FT /db_xref="InterPro:IPR002559" FT /db_xref="UniProtKB/TrEMBL:Q9R319" FT /protein_id="CAB61794.1" FT /translation="MPTSVTYTAVLDVRRSTAEHLAGLLCDHRIVARTRKGRRALGCFK FT QAVLVLRWFLDGTRLAQLARDNGLSVSTSYRYLHEGLAVLAAGAPDLSTALERAKAAGP FT THLNLDGTVIRTDRVAAPGPNGADLRWSGKHKHHGGNVQVIATPDGWPIWVSPVRPGRE FT HDTTCARHHGLVEALNRIAAELDMPTLVDFGYENAGDGFRHPFKKPAGSELTEEQQTYN FT KVIRGIHGVCERANSLLKTTFKALRRVSLDPSRITKIAAAALVLLQLEYDRTI" FT RBS complement(206584..206587) FT CDS complement(206755..207684) FT /transl_table=11 FT /gene="SCO3471" FT /gene_synonym="dagA" FT /gene_synonym="SCE65.07c" FT /product="extracellular agarase precursor" FT /note="SCE65.07c, dagA, extracellular agarase precursor, FT len: 309 aa; identical to previously sequenced FT SW:AGAR_STRCO (EMBL:X05811) Streptomyces coelicolor FT extracellular agarase precursor (EC 3.2.1.81) DagA, 309 aa FT and similar to TR:Q59078 (EMBL:M73783) Alteromonas FT atlantica (Pseudomonas atlantica) beta-agarase I precursor FT (EC 3.2.1.81), 290 aa; fasta scores: opt: 385 z-score: FT 446.1 E(): 1.8e-17; 33.2% identity in 304 aa overlap. FT Contains match to Prosite entry PS01034 Glycosyl hydrolases FT family 16 active sites. Contains N-terminal region signal FT sequence peptide" FT /db_xref="GOA:P07883" FT /db_xref="InterPro:IPR017909" FT /db_xref="UniProtKB/Swiss-Prot:P07883" FT /protein_id="CAB61795.1" FT /translation="MVNRRDLIKWSAVALGAGAGLAGPAPAAHAADLEWEQYPVPAAPG FT GNRSWQLLPSHSDDFNYTGKPQTFRGRWLDQHKDGWSGPANSLYSARHSWVADGNLIVE FT GRRAPDGRVYCGYVTSRTPVEYPLYTEVLMRVSGLKLSSNFWLLSRDDVNEIDVIECYG FT NESLHGKHMNTAYHIFQRNPFTELARSQKGYFADGSYGYNGETGQVFGDGAGQPLLRNG FT FHRYGVHWISATEFDFYFNGRLVRRLNRSNDLRDPRSRFFDQPMHLILNTESHQWRVDR FT GIEPTDAELADPSINNIYYRWVRTYQAV" FT misc_feature complement(206756..208494) FT /note="previously sequenced fragment (EMBL:X05811) 100% FT identity" FT misc_feature complement(207187..207222) FT /note="PS01034 Glycosyl hydrolases family 16 active sites" FT RBS complement(207692..207695) FT CDS complement(208038..208301) FT /transl_table=11 FT /gene="SCO3472" FT /gene_synonym="SCE65.08c" FT /product="putative transposase remnant" FT /note="SCE65.08c, possible transposase remnant, len: 87 aa; FT similar to TR:P71428 (EMBL:X02734) Lactobacillus casei FT transposable element ISL1, 93 aa; fasta scores: opt: 98 FT z-score: 145.6 E(): 0.91; 31.5% identity in 54 aa overlap FT and to Streptomyces coelicolor SCE65.24, 114 aa; fasta FT scores: opt: 76 z-score: 102.7 E(): 2.3; 40.6% identity in FT 32 aa overlap" FT /db_xref="GOA:Q9RKG5" FT /db_xref="InterPro:IPR002514" FT /db_xref="UniProtKB/TrEMBL:Q9RKG5" FT /protein_id="CAB61796.1" FT /translation="MGSKYTKRYLEEYKRDAIELVRSSGRTVTEAARELGISRSEPFQV FT RYGFGRDFSRTPETRGRCVGASAGHPHLPRRALGMPCTGRPA" FT RBS complement(208313..208317) FT CDS complement(209105..209752) FT /transl_table=11 FT /gene="SCO3473" FT /gene_synonym="SCE65.09c" FT /product="putative aldolase" FT /note="SCE65.09c, probable aldolase, len: 215 aa; similar FT to SW:ALKH_BACSU (EMBL:L47838) Bacillus subtilis KHG/KDPG FT aldolase AlkH, 347 aa; fasta scores: opt: 457 z-score: FT 523.2 E(): 9.1e-22; 39.5% identity in 200 aa overlap and to FT Streptomyces coelicolor SCE65.31c, 225 aa; fasta scores: FT opt: 424 z-score: 429.4 E(): 1.5e-18; 37.7% identity in 215 FT aa overlap. Contains Pfam match to entry PF01081 Aldolase, FT KDPG and KHG aldolase and match to Prosite entry PS00160 FT KDPG and KHG aldolases Schiff-base forming residue" FT /db_xref="GOA:Q9RKG4" FT /db_xref="HSSP:1EUA" FT /db_xref="InterPro:IPR013785" FT /db_xref="UniProtKB/TrEMBL:Q9RKG4" FT /protein_id="CAB61797.1" FT /translation="MPRYETASRIARDGVVAVVRSHSPDLAREQALALLKAGQRVVEVS FT MTTPGALDVVADLSHGWPAHEALIGVGTVLDEATVRMSELAGARFVVSPTVNRTVLRAA FT HRYGMATLAGALSPTEAATAIEEGADFVKLFPASVYGADAVRHLLAPFPQLALVPTGGV FT PLELAPDYIRAGAVAVGIGSELTSGDPRSIEGRVRQLRTAVAREKAERTARA" FT misc_feature complement(209153..209701) FT /note="Pfam match to entry PF01081 Aldolase, KDPG and KHG FT aldolase, score 71.80, E-value 1.4e-17" FT misc_feature complement(209330..209371) FT /note="PS00160 KDPG and KHG aldolases Schiff-base forming FT residue" FT RBS complement(209757..209761) FT CDS complement(209791..210792) FT /transl_table=11 FT /gene="SCO3474" FT /gene_synonym="SCE65.10c" FT /product="putative sugar kinase" FT /note="SCE65.10c, possible sugar kinase, len: 333 aa; FT similar to SW:KDGK_BACSU (EMBL:L47838) Bacillus subtilis FT 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) KdgK, 324 aa; FT fasta scores: opt: 500 z-score: 585.4 E(): 3.1e-25; 34.1% FT identity in 299 aa overlap. Contains Pfam match to entry FT PF00294 pfkB, pfkB family carbohydrate kinase" FT /db_xref="GOA:Q9RKG3" FT /db_xref="InterPro:IPR000408" FT /db_xref="UniProtKB/TrEMBL:Q9RKG3" FT /protein_id="CAB61798.1" FT /translation="MTRPVVEGGPAVVCLGETMAQIVPIDGLRLHEASACAFGVAGAES FT NVAISLSRLGTAAFWAGFVGDDPMGLRVLGELRRHGVVTKLARTMPGRRTGVYFKDPAP FT EGSDIYYYRSGSAATLMDGEYAERIAAVRPRWIHLTGVTPALSENCREAVISLIELAGD FT TGASVSFDVNYRPSLWPARDAAAQSLMAIADRCNVVFVGLDEAQTLWKSCTAGAVRDHL FT PSPDVVVVKDGGREAVAFRGGRRTAVPALPVDVVEPVGAGDAFAAGWIHGALVGLDEAG FT CLRLGHLLAGAAMTSLSDVADLPTAPAALVARAKHGNEWPGHGSPAEASPHP" FT misc_feature complement(209989..210672) FT /note="Pfam match to entry PF00294 pfkB, pfkB family FT carbohydrate kinase, score 85.30, E-value 8e-26" FT RBS complement(210803..210806) FT CDS complement(210920..212053) FT /transl_table=11 FT /gene="SCO3475" FT /gene_synonym="SCE65.11c" FT /product="putative isomerase" FT /note="SCE65.11c, possible isomerase, len: 377 aa; similar FT to SW:ATB_RHOOP (EMBL:X99622) Rhodococcus opacus muconate FT cycloisomerase I (EC 5.5.1.1) CatB, 373 aa; fasta scores: FT opt: 390 z-score: 443.3 E(): 2.6e-17; 31.1% identity in 357 FT aa overlap. Contains Pfam match to entry PF01188 MR_MLE, FT Mandelate racemase / muconate lactonizing enzyme family FT PS00908 Mandelate racemase / muconate lactonizing enzyme FT family signature 1 PS00909 Mandelate racemase / muconate FT lactonizing enzyme family signature 2" FT /db_xref="GOA:Q9RKG2" FT /db_xref="InterPro:IPR018110" FT /db_xref="UniProtKB/TrEMBL:Q9RKG2" FT /protein_id="CAB61799.1" FT /translation="MRIVKVRTFHVRPRWLFVAVETDKGVIGWGEAVVEGQARVVERMI FT GDLAEYLAGRDPRRIEHHWQGMYRGAFYRGGAVLCSAISGIDQALWDITARDLGVPVHA FT LLGGAVRDSVRMYGHARGVTDAEFAHAARRSRSAGMTAIKFGLDGPVRALDTVEYVDRQ FT VARVAAVREAVGPAFDIALDFHGRTSPAMARRLAERLSPMGPLFIEEPCLPENVDALAE FT IARATNVPIAAGERIFTKWGFRELLERRAVSVVQPDLCHAGGISEVRRIAAMAEAHYVA FT LAPHNPLGPVSLAACLQVAASTPNFLIQEYLALDDGADLGAGILAVPFSVENGHIAVPT FT GPGLGIEVDEAQLMDRVYAGDWTTPRFTHQDGSHGDW" FT misc_feature complement(211040..212044) FT /note="Pfam match to entry PF01188 MR_MLE, Mandelate FT racemase / muconate lactonizing enzyme family, score FT 298.10, E-value 1.1e-85" FT misc_feature complement(211421..211516) FT /note="PS00909 Mandelate racemase / muconate lactonizing FT enzyme family signature 2" FT misc_feature complement(211733..211810) FT /note="PS00908 Mandelate racemase / muconate lactonizing FT enzyme family signature 1" FT RBS complement(212063..212066) FT CDS complement(212266..213021) FT /transl_table=11 FT /gene="SCO3476" FT /gene_synonym="SCE65.12c" FT /product="putative short-chain dehydrogenase" FT /note="SCE65.12c, probable dehydrogenase, len: 251 aa; FT similar to SW:KDUD_BACSU (EMBL:L47838) Bacillus subtilis FT 2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125) KduD, FT 254 aa; fasta scores: opt: 833 z-score: 937.8 E(): 0; 52.0% FT identity in 248 aa overlap and to Streptomyces coelicolor FT SCI30A.02, 253 aa; fasta scores: opt: 605 z-score: 622.2 FT E(): 2.7e-29; 44.1% identity in 245 aa overlap. Contains FT Pfam matches to entry PF00106 adh_short, short chain FT dehydrogenase and to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus and match to FT Prosite entry PS00061 Short-chain dehydrogenases/reductases FT family signature" FT /db_xref="GOA:Q9RKG1" FT /db_xref="HSSP:1FJH" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RKG1" FT /protein_id="CAB61800.1" FT /translation="MISSFDLTGRTAVVTGGGRGLGLGISRALLNAGADVVVLSRSALD FT DRLRRTAADLGRSVSHVGVDLRDREGVAAAGAEVLAGHQVDILVNNAGAQIRHPAEDFP FT LDAWDAVLDVNLRSVVQLCQIFGRPMIQRGEGKIINLASLLSFQGGFTVAAYAASKGAV FT AQLTKALCNEWAGRGVNVNAIAPGYMATEMNTALLEDPVRLEQLSVRIPAGRWGGPDDV FT GDVAVFLASRAAAYVHGQVLAVDGGWLAR" FT misc_feature complement(212290..212382) FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 50.50, FT E-value 3.6e-11" FT misc_feature complement(212446..212994) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 208.70, E-value 9.1e-59" FT misc_feature complement(212509..212595) FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT CDS complement(213018..214052) FT /transl_table=11 FT /gene="SCO3477" FT /gene_synonym="SCE65.13c" FT /product="putative dehydrogenase" FT /note="SCE65.13c, possible dehydrogenase, len: 344 aa; FT similar to TR:CAB50292 (EMBL:AJ248287) Pyrococcus abyssi FT threonine 3-dehydrogenase (EC 1.1.1.103) 348 aa; fasta FT scores: opt: 567 z-score: 616.8 E(): 5.6e-27; 33.8% FT identity in 328 aa overlap and to SW:TDH_BACSU FT (EMBL:Z99112) threonine 3-dehydrogenase (EC 1.1.103) Tdh, FT 347 aa; fasta scores: opt: 544 z-score: 592.1 E(): 1.3e-25; FT 31.4% identity in 331 aa overlap. Contains Pfam match to FT entry PF00107 adh_zinc, Zinc-binding dehydrogenases" FT /db_xref="GOA:Q9RKG0" FT /db_xref="HSSP:1KOL" FT /db_xref="InterPro:IPR013154" FT /db_xref="UniProtKB/TrEMBL:Q9RKG0" FT /protein_id="CAB61801.1" FT /translation="MTGGMSAVVWAGVNDVRVEEVPMPEVPPGWALVRVACTGICGTDL FT GIVHGKHPRARQGLILGHEISGWVEVTAPGGPPEGALVVAEPLISCKDCRACREGHSHV FT CARLGLFGIDAPGGAAQFVALPTSTLHQVPSRVEPTQAALTEPLAVAVHAVSRSGMEAG FT DVVAVFGAGPIGILTALVARHEGASHVVVAEPNARRRAVASDMGLIAVPDGAQLRDMVA FT ELSQGDGADTTFDSAAHPAVAAELADVTRVLGRVVIVGVYKEPAAVDLQAVCFKEQSVV FT GVRVYTREDFRTAIDLVAQNALGLDRFPVSVYGFDRISDAFDAAATGSGGLKVLISTHR FT DEAT" FT misc_feature complement(213042..214037) FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score 148.10, E-value 1.5e-40" FT CDS complement(214049..215083) FT /transl_table=11 FT /gene="SCO3478" FT /gene_synonym="SCE65.14c" FT /product="putative dehydrogenase" FT /note="SCE65.14c, probable dehydrogenase, len: 344 aa; FT similar to TR:O50095 (EMBL:AP000006) Pyrococcus horikoshii FT 307aa long hypothetical phosphoglycerate dehydrogenase FT PH1387, 307 aa; fasta scores: opt: 687 z-score: 777.1 E(): FT 0; 40.5% identity in 291 aa overlap and to SW:SERA_METTH FT (EMBL:AE000870;) Methanobacterium thermoautotrophicum FT D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) SerA, 525 FT aa; fasta scores: opt: 664 z-score: 748.1 E(): 0; 39.0% FT identity in 282 aa overlap. Contains Pfam match to entry FT PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid FT dehydrogenases and match to Prosite entry PS00670 D-isomer FT specific 2-hydroxyacid dehydrogenases signature 2" FT /db_xref="GOA:Q9RKF9" FT /db_xref="HSSP:1HKU" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RKF9" FT /protein_id="CAB61802.1" FT /translation="MIRLMTAMRTAGGGPLVAITECDHDSFDIERDVVTSAGGQLLVTQ FT SRDADTMVVNCAGADAIVVQYAAITEQVMDRLPRLKVIGRYGVGVDSVDVEAATRRGIL FT VCNVPDYGTEAVSDHAIGLALSVARGIPRLDRGVRAGSFDLPAVRPLYQVGQRVFGVVG FT MGLIGAATARKAAGLGYDVIAYDSAADPDAQTFRGFRSVGLHELLERAQVVSVHTPLTE FT QTRGLLGADAFARMRPDAIVVNTSRGGVIDTGALVDALKRGAVAGAGIDVHEIEPLPRD FT HPLTSFDNVVLTPHLAWYSEESYAELKRRTVENVVDACAGRTPRNVVNPEALPAAAQRS FT EGRR" FT RBS complement(214060..214064) FT misc_feature complement(214199..214819) FT /note="Pfam match to entry PF00389 2-Hacid_DH, D-isomer FT specific 2-hydroxyacid dehydrogenases, score 237.30, FT E-value 7.1e-97" FT misc_feature complement(214397..214465) FT /note="PS00670 D-isomer specific 2-hydroxyacid FT dehydrogenases signature 2" FT RBS complement(215085..215088) FT CDS complement(215445..218432) FT /transl_table=11 FT /gene="SCO3479" FT /gene_synonym="SCE65.15c" FT /product="putative beta-galatosidase" FT /note="SCE65.15c, possible beta-galatosidase, len: 995 aa; FT similar to SW:BGAL_ECOLI (EMBL:J01636) Escherichia coli FT beta-galactosidase (EC 3.2.1.23) (lactase) lacZ, 1023 aa; FT fasta scores: opt: 1594 z-score: 1693.3 E(): 0; 33.6% FT identity in 1039 aa overlap. Contains Pfam match to entry FT PF00703 Glyco_hydro_2, Glycosyl hydrolases family and match FT to Prosite entry PS00719 Glycosyl hydrolases family 2 FT signature 1" FT /db_xref="GOA:Q9RKF8" FT /db_xref="HSSP:1F49" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:Q9RKF8" FT /protein_id="CAB61803.1" FT /translation="MLPIIGALRPWADPTMTSLLRLPMRARPAAEGDRRLSLDGTWSFR FT LFPSPDQVPADAVRGERAPGQWQSVDVPGSWPVQVADDIPHYTNIQMPFAEPPPRLPSR FT NPTGVYRTGFDVPSHWEGQRLLLHVGGADSVHAVYLNGVFVGYGTDARLGSEYDVTEAA FT RVGRNQLAVVVVRYSAHSFLEDQDGWWLAGLHRGVRVEARPPVGLVDLDARADLDPRSG FT EGSLDVRATVDFGESTAAEGYRVRVSLSGRDGAGVAGPQDAPVPHAVNNTYEFSGHIAR FT LHRDGLRILPWSAETPTLYEVAAELIDPAGDVVDATRVRVGFRRVEIDGPDFLVNGRRV FT WIFGVNRHDHHPDTGAAVTAEDMRADLAAMRRMNINAIRTSHYPNDPAFYDLCDELGFY FT VVDEANIESHAFNWYLCGDPRYRATWLERGARMVARDRNHPCVVQWSLGNESGYGVNHD FT ALAGWIRRADRSRPLHYEDAIRNSGWTDGGRHATDVVCPMYPGIEEIRAYGEQVAAGAA FT DRPLIMCEYSHAMGNSNGSLADYWDVITSTPGLQGGFIWEWKDHGLRQRLPDGTTRLAY FT GGQFGDAPHDANFVADGLVSADVEPHPGTAEVAWVYRPVTTEYVDGGLYVTNRRRFAGT FT GDLAAGWELLLDGAPSASGTLDVPDIAPGGSVAVPLPADAARAGAAQALLTITWRTRTE FT SWFAPAGHPVAWDQLALRDGRTAPGPPVNGAVAVPGETADDPVPNVWRAATDNDGLKLM FT EHIVRVREMGSRTLIRWRDAGLDTRPAHEIVDHTVSVSRSESGADYRHRFEVPDEAADL FT PRVGVLFRVDPRFDRFVWFGRGPHENYPDRNRSAMLGRWSSHVEPSPYLVPQEFGLRTG FT TLWLELIDDDRGDRLRLTSLGGDFCWSATRYAPQALFAAGNASDLREDGRLVVCLDAAH FT RGVGTGACGPDVLPEYRIGPGRYELAYRMELVPAVQGVAGAPPHPQDSSRAASGGGSQC FT KDRHVG" FT misc_feature complement(216609..218339) FT /note="Pfam match to entry PF00703 Glyco_hydro_2, Glycosyl FT hydrolases family 2, score 561.00, E-value 7.7e-165" FT misc_feature complement(217230..217307) FT /note="PS00719 Glycosyl hydrolases family 2 signature 1" FT CDS complement(218573..219658) FT /transl_table=11 FT /gene="SCO3480" FT /gene_synonym="SCE65.16c" FT /product="putative racemase" FT /note="SCE65.16c, possible racemase, len: 361 aa; similar FT to TR:CAB55709 (EMBL:AL117387) Streptomyces coelicolor FT possible racemase SCF41.06, 416 aa; fasta scores: opt: 471 FT z-score: 557.6 E(): 1.1e-23; 32.6% identity in 328 aa FT overlap and to SW:MANR_PSEPU (EMBL:M19043) Pseudomonas FT putida mandelate racemase (EC 5.1.2.2) MdlA, 359 aa; fasta FT scores: opt: 473 z-score: 561.0 E(): 7.2e-24; 27.8% FT identity in 363 aa overlap. Contains Pfam match to entry FT PF01188 MR_MLE, Mandelate racemase / muconate lactonizing FT enzyme family and match to Prosite entry PS00909 Mandelate FT racemase / muconate lactonizing enzyme family signature 2" FT /db_xref="GOA:Q9RKF7" FT /db_xref="InterPro:IPR018110" FT /db_xref="PDB:2OVL" FT /db_xref="UniProtKB/TrEMBL:Q9RKF7" FT /protein_id="CAB61804.1" FT /translation="MIERVRTDLYRIPLPTRLTDSTHGAMMDFELITVRIEDSDGATGL FT GYTYTVNHGGAAVATMVDKDLRGCLLGADAEQIEKIWQSMWWRLHYAGRGGHATSAISA FT VDIALWDLKGIRARTPLWKLFGGYDPVVPVYAGGIDLELPVADLKTQADRFLAGGFRAI FT KMKVGRPDLKEDVDRVSALREHLGDSFPLMVDANMKWTVDGAIRAARALAPFDLHWIEE FT PTIPDDLVGNARIVRESGHTIAGGENLHTLYDFHNAVRAGSLTLPEPDVSNIGGYTTFR FT KVAALAEANNMLLTSHGVHDLTVHALASVPHRTYMEAHGFGLHAYMAEPMAVTDGCVSA FT PDRPGHGVVLDFERLGRLAVG" FT misc_feature complement(218639..219658) FT /note="Pfam match to entry PF01188 MR_MLE, Mandelate FT racemase / muconate lactonizing enzyme family, score FT 144.80, E-value 1.5e-39" FT misc_feature complement(218990..219085) FT /note="PS00909 Mandelate racemase / muconate lactonizing FT enzyme family signature 2" FT CDS complement(219720..220832) FT /transl_table=11 FT /gene="SCO3481" FT /gene_synonym="SCE65.17c" FT /product="hypothetical protein SCE65.17c" FT /note="SCE65.17c unknown, len: 370 aa" FT /db_xref="UniProtKB/TrEMBL:Q9RKF6" FT /protein_id="CAB61805.1" FT /translation="MTMPAESAATVRGRRYPADPEWFCDFRTFPVQGLGPEVGVHRRDP FT SSVLTVDGRYHVWYTRSTGETDGFGTGDPMAKVFPWDWSEIWHATSDDGATWVEQGRAL FT GRGEPGSYDDRSVFTPEVLEHQGWFYLVYQVIRSPYALRSFESIAMAKAPSPDGPWVRS FT PQPILRPQADGEWAGEEDNRLSVVSQGSFDSHKVHDPILVPFQGRFFLYYKGEQMGEGF FT SAGGRTTRWGLAIADDIEGPYHRCPANPVTNSGHETCVWRYGDGIAAMLTTDGPERNTI FT QFAPDGINFEIMAHIANPPVATGPLRLPDHAVAPLDGVRWGLCHDVTASWHYIQGFAAD FT ERQKMFYTRGLSPETAESAEADALPAPHEK" FT RBS complement(220842..220845) FT CDS complement(220859..221740) FT /transl_table=11 FT /gene="SCO3482" FT /gene_synonym="SCE65.18c" FT /product="putative sugar-permease" FT /note="SCE65.18c, possible sugar-permease, len: 293 aa; FT similar to TR:P72399 (EMBL:Y07706) Streptomyces coelicolor FT putative maltose permease MalG, 302 aa; fasta scores: opt: FT 491 z-score: 561.6 E(): 6.6e-24; 28.2% identity in 301 aa FT overlap. Contains match to Pfam entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component and match to Prosite entry PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign. Contains possible N-terminal region signal FT peptide sequence" FT /db_xref="GOA:Q9RKF5" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9RKF5" FT /protein_id="CAB61806.1" FT /translation="MTTPVHSALRAGTATPAADRITRKQRRESAAGWAKTAVMSVVTLV FT ALAPIIMILVLSVRSGQTASGTYSWNFSNYVEIFSKTPVLDYLYNSLAVTLGTTVFAVV FT IGALAGYPMSRLRNRFIGGYTLSLFVVQSLPVIVFVIPLFVVFAKIGMADTLSGVAVIF FT IAGGMAVTCWMMAAYYDSIPVELEEAAWVDGASLWGGFVRVVLRNSYPGILSAAIFSFL FT VAWNDYLVATVFLRSQSNFTLPIGLQTYFQQNATDWGPVMAMSVVMLLPPVIVFAVLNR FT FFSIGGIGGAIK" FT misc_feature complement(220985..221209) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 52.20, E-value 1.2e-11" FT misc_feature complement(221120..221206) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT RBS complement(221750..221753) FT CDS complement(221752..222699) FT /transl_table=11 FT /gene="SCO3483" FT /gene_synonym="SCE65.19c" FT /product="putative integral membrane transport protein" FT /note="SCE65.19c, probable integral membrane transport FT protein, len: 315 aa; similar to TR:O50452 (EMBL:AL021006) FT Mycobacterium tuberculosis probable sugar transport protein FT MTV006.08, 307 aa; fasta scores: opt: 542 z-score: 668.9 FT E(): 7e-30; 32.6% identity in 288 aa overlap. Contains FT match to Pfam entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component and possible N-terminal region signal peptide FT sequence" FT /db_xref="GOA:Q9RKF4" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9RKF4" FT /protein_id="CAB61807.1" FT /translation="MTDVSVPTRSAARTDRPRGRERKAESRHPGSKKTMAAMLAPSIFL FT LIALNAYPLFYAVSQSLRDGGIAGPGEFIGLENYTTALQDPAFWEAVRFTLLFTVVSVF FT VAWVIGTALALVLRRSFPGRSVFRVLLLLPWVVPVVVSTTSWNFLVATPSSPVPTLLRE FT LGFGDVQILANPGSAMAIVIIFKIWGTVPFMMMMMSSALQAVDPSVEEACRLDGASRWQ FT RIRHVILPIMSKPVYIAWVLASIFTINDFPSVFLLTGGGPVGSTSTLVVFAYRLVFQDF FT RTGYGVAVAFLITTALIAMSIYFFRRINRASANG" FT misc_feature complement(221866..222099) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 60.80, E-value 3e-14" FT CDS complement(222735..224045) FT /transl_table=11 FT /gene="SCO3484" FT /gene_synonym="SCE65.20c" FT /product="putative secreted sugar-binding protein" FT /note="SCE65.20c, possible secreted sugar-binding protein, FT len: 436 aa; similar to TR:P72397 (EMBL:Y07706) FT Streptomyces coelicolor putative maltose-binding protein FT MalE, 423 aa; fasta scores: opt: 361 z-score: 398.4 E(): FT 8.1e-15; 26.2% identity in 409 aa overlapand to TR:O87856 FT (EMBL:AL031013) Streptomyces coelicolor putative secreted FT sugar binding protein SC8A6.22, 438 aa; fasta scores: opt: FT 344 z-score: 379.6 E(): 9e-14; 23.6% identity in 365 aa FT overlap. Contains match to Pfam entry PF01547 FT SBP_bacterial_1, Bacterial extracellular solute-binding FT protein and match to Prosite entry correctly situated FT PS00013 Prokaryotic membrane lipoprotein lipid attachment FT site. Contains possible N-terminal signal peptide sequence" FT /db_xref="GOA:Q9RKF3" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q9RKF3" FT /protein_id="CAB61808.1" FT /translation="MTKPVVPSGVSRRGFLGGSLGVAGAVLLAACSGGGNSSQGSGGSK FT FAFWDMPWGSPGPDYLAAGKEISAAFSGGSATYQSISWDGWLQTFSSAIAAGTGPAIST FT GGAFQSLQYYVQDAVHPADGVIAKLRSKGQLDDFLPGTLDVFKYKGAYTALPWNVDSRL FT LWYRKSLLEKAGVEEPRSWDDLYRVGVALKKNDVYGMVASGGAGGNAYQTFLSFVFNNG FT GGLFDKDGEPQCVTDANVEAVEFLMKLAKDGIMDPGSVSYTVANLNDQFSSGAAALSIL FT PPDIANSFEDPRLKADITLGSPLTSPNGTKGTMAYTSDLILYTGDWDTDVVEDFAVYYL FT DAMSAYWKKGVLNKVPVRQSILDLPEVQAQPNLVKATKEWLPVGKSLTQLAGEPFPEIN FT AVDGGQAITQWAQQVIQAKSSGEQTLRTLQDGIEKVM" FT misc_feature complement(222744..223601) FT /note="Pfam match to entry PF01547 SBP_bacterial_1, FT Bacterial extracellular solute-binding protein, score FT 71.70, E-value 1.6e-17" FT misc_feature complement(223953..223985) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS complement(224053..224056) FT stem_loop complement(224154..224201) FT CDS complement(224227..225276) FT /transl_table=11 FT /gene="SCO3485" FT /gene_synonym="SCE65.21c" FT /product="putative lacI-family transcriptional regulator" FT /note="SCE65.21c, probable lacI-family transcriptional FT regulator, len: 349 aa; similar to TR:AAD42741 FT (EMBL:AF105219) Thermomonospora curvata putative regulatory FT protein AglR, 347 aa; fasta scores: opt: 563 z-score: 648.1 FT E(): 1e-28; 34.9% identity in 341 aa overlap and to FT SW:CYTR_ECOLI (EMBL:X03683) Escherichia coli, FT transcriptional repressor CytR 341 aa; fasta scores: opt: FT 552 z-score: 635.6 E(): 5e-28; 30.5% identity in 347 aa FT overlap. Contains matches to Pfam entries PF00356 lacI, FT Bacterial regulatory proteins, lacI family PF00532 FT Peripla_BP_like, Periplasmic binding proteins and LacI. FT Contains probable helix-turn-helix motif at residues 18..39 FT (+4.84 SD)" FT /db_xref="GOA:Q9RKF2" FT /db_xref="HSSP:1LCC" FT /db_xref="InterPro:IPR001761" FT /db_xref="UniProtKB/TrEMBL:Q9RKF2" FT /protein_id="CAB61809.1" FT /translation="MTSEAGAGQAKALPARARLVDVAKRAGVTKSVVSRILNDDTTLRI FT RPETRERVLAVAAELGYRPNVTARALSVSRTRAFALLIPDLSNSVYAAVTRGAFRRARD FT HGYVLLIAEDAAGDDDAAYAELVTAGRVDGLLVASSRPEHPLVERLLADRGGLAHVFLN FT REVQGSNRNVGMDMQGASALVVDHLHDRGHRHIGMVTGPLDLAPARSRLDGFQGRLREL FT GLDDTAHFAGTFSEAGGCAAAHGLLDARPELTALYASTFPQAVGVMKAVRDRGWKVPAD FT VSLIAYDDLPMAEFLDPPLTTLAMPLATLGAAAVDALVDQIEGRVIGSRQVLGGYEIVE FT RASVAVPRV" FT misc_feature complement(224335..225054) FT /note="Pfam match to entry PF00532 Peripla_BP_like, FT Periplasmic binding proteins and LacI family., score 68.80, FT E-value 1.2e-16" FT misc_feature complement(225151..225234) FT /note="Pfam match to entry PF00356 lacI, Bacterial FT regulatory proteins, lacI family, score 27.20, E-value FT 3.9e-06" FT RBS complement(225285..225288) FT RBS 225427..225431 FT CDS 225438..226916 FT /transl_table=11 FT /gene="SCO3486" FT /gene_synonym="SCE65.22" FT /product="putative aldehyde dehydrogenase" FT /note="SCE65.22, probable aldehyde dehydrogenase, len: 492 FT aa; similar to SW:ALDA_ECOLI (EBML:M64541) Escherichia FT coli aldehyde dehydrogenase A (EC 1.2.1.22) aldA, 478 aa; FT fasta scores: opt: 1189 z-score: 1347.0 E(): 0; 39.1% FT identity in 473 aa overlap and to Streptomyces coelicolor FT SCI35.34c, 483 aa; fasta scores: opt: 1014 z-score: 940.7 FT E(): 0; 40.2% identity in 455 aa overlap. Contains match to FT Pfam entry PF00171 aldedh, Aldehyde dehydrogenase and two FT matches to Prosite entries PS00687 Aldehyde dehydrogenases FT glutamic acid active site PS00070 Aldehyde dehydrogenases FT cysteine active site" FT /db_xref="GOA:Q9RKF1" FT /db_xref="HSSP:1O02" FT /db_xref="InterPro:IPR016162" FT /db_xref="UniProtKB/TrEMBL:Q9RKF1" FT /protein_id="CAB61810.1" FT /translation="MTHELFDSKGLLGSAPAAFVAGEYELDSSHGTLPVINPANGQLVA FT EVPSSSSSTVDRAVTAAVAAQREWGRRSHVARAAVLEAVRDAIAVHADELARIVSVEQG FT KPLSDARGETEGACAFFDFAISQKYRAVGSMMASEPGRSLGVREEPIGVVAAILPWNFP FT VAIFARKVAPALMAGNAVVLKPSELTPLSALALARLCRLAGVPDGLLSVVCGEGKDTGR FT ALVTHPGVGMVTMTGSTRGGREILAQVADQIIPVSLELGGKAPFIVFEDADLDAAVEAA FT ADARLWNTGQVCTCNEVTYVHADLHDEFVRRVVDRFASVTPLDPFAAGSRLGPLVAERE FT RTRVQGMVDAAVAAGARVRTGGGRPDGEQYQSGAWFAPTVLTNVRPEMDIARREVFGPV FT LPIIPFDAEAEVVSAANSTAYGLTAYVYTRDLSRAMRMIDALEFGEVYVNQAGPEQVQG FT FHTGWKSSGLGGDDGPHGYEKYLRRKTVYVRHAV" FT misc_feature 225504..226907 FT /note="Pfam match to entry PF00171 aldedh, Aldehyde FT dehydrogenase, score 617.50, E-value 7.6e-182" FT misc_feature 226209..226232 FT /note="PS00687 Aldehyde dehydrogenases glutamic acid active FT site" FT misc_feature 226293..226328 FT /note="PS00070 Aldehyde dehydrogenases cysteine active FT site" FT RBS 227289..227293 FT CDS 227299..229695 FT /transl_table=11 FT /gene="SCO3487" FT /gene_synonym="SCE65.23" FT /product="putative hydrolase" FT /note="SCE65.23, possible hydrolase, len: 798 aa; similar FT to SW:AGAB_VIBS7 (EMBL:D21202) Vibrio sp. (strain JT0107) FT beta-agarase B (EC 3.2.1.81) AgaB, 955 aa; fasta socres: FT opt: 1394 z-score: 1581.4 E(): 0; 39.0% identity in 772 aa FT overlap. Contains possible hydrophobic membrane spanning FT region and Leucine TTA codon, possible target for bldA FT regulation" FT /db_xref="GOA:Q9RKF0" FT /db_xref="UniProtKB/TrEMBL:Q9RKF0" FT /protein_id="CAB61811.1" FT /translation="MTVHKRACTTPPPRASRSFRVRWPVLIAAACAGLVLATTSPPAVA FT AGAHDLGDETMLYDFQDGLVPAEVGPYQAKTTIVGRGDKKLRVDFQARKNYYSSFSVRP FT EPVWNWSAEESESLGIAMELTNPSDRSVQLTIDLESSTGVATRSVNVPAGGGGTYYFDV FT DSPALHRDTGLRADPSWLADKDVTSAVWMWGSKETDTSRISQLNFYVAGLLHDRSVIVD FT DIRVVRDAPADPDYLKGLVDAFGQNNKVDYKGKVSRTSEILRQRAAEAKDLRRHPVPED FT RSRYGGWLNGPRLEATGNFRVEKYQGRWTLVDPDGYLFFSTGIDNARMFDSPTTTGYDF FT DHDAIQELPPPSLTAGGPEDLNRVQKSALPTRTKMSETRADLFSKLPKYRTRAGEGFGY FT APDTLAGPVAQGETYSFYKANVARKYPGSNYMERWRDNTVDRMLSWGFTSFGNWTDPEM FT YDNDRIPYFAHGWIKGDFKTVSTGQDYWGPMPDPFDPAFSDAAARTARAVADEVADSPL FT AIGVFMDNELSWGNAGSFSTRYGVVIDTMSRDAAESPTKSAFSDELEEKYGTIDALNAA FT WQTTVPSWEALRSGSADLGSDETAKESDYSALMTLYATQYFKTVDAELDKVMPDHLYAG FT SRFASWGRTPEVVEAASKYVDIMSYNEYREGLHPSEWAFLEELDKPSLIGEFHMGTTTT FT GQPHPGLVSAGTQAERARMYAEYMEQLIDNPYMVGGHWFQYADSPVTGRALDGENYNIG FT FVSVTDRPYPEIVAAARDVNQRLYDRRYGNLATAEGHYTGRRSAE" FT misc_feature 227398..227400 FT /gene="none" FT /note="Leucine TTA codon. Possible target for bldA FT regulation" FT RBS 229846..229849 FT CDS join(229864..230208,230205..230381) FT /pseudo FT /transl_table=11 FT /gene="SCO3488" FT /gene_synonym="SCE65.24" FT /gene_synonym="SCE65.25" FT /product="putative transposase remnant" FT /note="SCE65.24, probable transposase remnant, len: 114 aa; FT similar to TR:Q46068 (EMBL:X69104) Corynebacterium FT glutamicum IS3 related insertion element, 97 aa; fasta FT scores: opt: 206 z-score: 280.7 E(): 2.9e-08; 41.6% FT identity in 101 aa overlap and to Streptomyces coelicolor FT SC3A7.06c, 95 aa; fasta scores: opt: 260 z-score: 287.9 FT E(): 1.1e-10; 53.7% identity in 95 aa overlap. Contains a FT possible helix-turn-helix motif at residues 38..59 (+4.10 FT SD) and a probable coiled-coil at residues 76..104, max FT score: 1.403 (probability 0.73)" FT /note="SCE65.25, possible transposase remnant, len: 58 aa; FT similar to TR:Q46069 (EMBL:X69104) Corynebacterium FT glutamicum IS3 related insertion element (fragment), 298 FT aa; fasta scores: opt: 102 z-score: 164.4 E(): 0.082; 39.5% FT identity in 38 aa overlap" FT RBS 230196..230200 FT repeat_region 230406..230442 FT /note="37 bp IR for IS6466" FT misc_feature 230406..232033 FT /note="previously sequenced fragment (EMBL:AB032065)" FT repeat_region 230406..232058 FT /note="IS6466" FT CDS 230455..231996 FT /transl_table=11 FT /gene="SCO3490" FT /gene_synonym="IS466A" FT /gene_synonym="SCE65.26" FT /product="transposase" FT /note="SCE65.26,IS466A, transposase, len: 513 aa; identical FT to previously sequenced TR:BAA84090 (EMBL:AB032065) FT Streptomyces coelicolor transposase IS466A-ORF, 513 aa and FT identical also to previosuly sequenced TR:CAB52795 FT (EMBL:AJ245804) Streptomyces coelicolor putative FT transposase TnpA, 513 aa, to Streptomyces coelicolor FT SCE65.05c and higly similar to Streptomyces coelicolor FT SCE65.04, 501 aa; fasta scores: opt: 2079 z-score: 2040.2 FT E(): 0; 63.7% identity in 501 aa overlap. Contains Leucine FT TTA codon, possible target for bldA regulation and a FT possible helix-turn-helix motif at residues 291..312 (+3.15 FT SD)" FT /db_xref="GOA:Q9R2U5" FT /db_xref="InterPro:IPR017894" FT /db_xref="UniProtKB/TrEMBL:Q9R2U5" FT /protein_id="CAB61814.1" FT /translation="MSVESLNELVATAFSGISPLVIEDVVDEGERVVVRARTPGSTAVC FT PACGALSERVHGYHWRTVADLPIDGRRVVVRVRVRRLVCPTRGCRHTFREQLPGVLERY FT QRRTARLTRQIKAVVKELAGRAGSRLLAKLAIGLSRHTALRTLLRIALPTGRVPRVIGV FT DDFALRRRHRYATVVIDAETHERIDVLPDRTADTLEAWLRENPGVEVVCRDGSATYAEA FT IRRALPDAVQVTDRWHLWHNLCETALSEVKAHSTCWAAVLDTPIYEGPRAQTTLERWHQ FT VHGLLQQRVSLLECARRLQLSLNTVKRYARADRPERMLRVPKYRASLVDPYRDHLRRRR FT AEDPAVPVQHLFEEIKALGFTGCLNLLHKYINQGRADADRSHISPRRLARMLLTRPENL FT KSGHRDLLDQLTAACPEMTHLATSVRTFAQLLKPRPENVDALDHWITQVRAADLPHLHA FT FTRGLERDNDAVIAALTLPYSNGPTEGVNTKTKRIARQMHGRAGFNLLRHRILLG" FT misc_feature 230551..231492 FT /note="Pfam match to entry PF01610 Transposase_12, FT Transposase, score 58.60, E-value 1.4e-13" FT misc_feature 230818..230820 FT /gene="none" FT /note="Leucine TTA codon. Possible target for bldA FT regulation" FT repeat_region 232006..232058 FT /note="53 bp IR for IS6466" FT CDS 232650..233183 FT /transl_table=11 FT /gene="SCO3491" FT /gene_synonym="SCE65.27" FT /product="possible transmembrane protein" FT /note="SCE65.27, possible transmembrane protein, len: 177 FT aa; highly similar to TR:CAB41065 (EMBL:AL049645) FT Streptomyces coelicolor hypothetical 15.4 KD protein FT SCE2.06, 146 aa; fasta scores: opt: 780 z-score: 972.8 E(): FT 0; 90.9% identity in 132 aa overlap" FT /db_xref="GOA:Q9RKE7" FT /db_xref="UniProtKB/TrEMBL:Q9RKE7" FT /protein_id="CAB61815.1" FT /translation="MTSPCNSSGTPVSSRSTTGTADAIAFPPPLRSTDQAAIATHAVLR FT ADALLYLLFGILGPAMAFASLAWLTGNLTNTCVGSGTWAPFRVTDALLHPEVMWPALST FT SMLTVGARVVPALFTVALVVTAAVLWVRWRAGSKSGLARKADLAPLLDKEIVAKAKSLR FT PSLGGRESKRGPAR" FT CDS complement(233353..233481) FT /transl_table=11 FT /gene="SCO3492" FT /gene_synonym="SCE65.28c" FT /product="hypothetical protein SCE65.28c" FT /note="SCE65.28c, unknown, len: 42 aa" FT /db_xref="UniProtKB/TrEMBL:Q9RKE6" FT /protein_id="CAB61816.1" FT /translation="MPDEPSAASRTSTTGSRMRSAAFPTGSGMERWKVGTRVPFPG" FT CDS complement(233471..234058) FT /transl_table=11 FT /gene="SCO3493" FT /gene_synonym="SCE65.29c" FT /product="putative acetyl transferase" FT /note="SCE65.29c, possible acetyl transferase, len: 195 aa; FT similar to TR:AAD15402 (EMBL:AC006223) Arabidopsis thaliana FT putative alanine acetyl transferase F22D22.23, 183 aa; FT fasta scores: opt: 208 z-score: 273.8 E(): 7.1e-08; 30.8% FT identity in 172 aa overlap and to SW:ATDA_ECOLI FT (EMBL:D25276) Escherichia coli spermidine FT N1-acetyltransferase (EC 2.3.1.57) SpeG, 185 aa; fasta FT scores: opt: 163 z-score: 216.7 E(): 0.00011; 23.6% FT identity in 174 aa overlap. Contains match to Pfam entry FT PF00583 Acetyltransf, Acetyltransferase (GNAT) family" FT /db_xref="GOA:Q9RKE5" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9RKE5" FT /protein_id="CAB61817.1" FT /translation="MSRRPVTLHRIVFTDWLAVHSWAGLPDACRFQPWGPNTEEQTRDF FT VRAAAEAWTHIRPRRLAHVARVGNAVVGMGDLHVRSHTQRQGEISYIVHPRVWGQGIGT FT EIGRSLLSLGFDRWGLHRIRATCDPRNQASSRVLTKLGMTYEGRHRHTAWIRDGWRDSL FT VFSIIEDEWHEATRSGADAVAEGLPPRRPGAG" FT misc_feature complement(233627..234037) FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 19.20, E-value FT 0.016" FT CDS complement(234113..235093) FT /transl_table=11 FT /gene="SCO3494" FT /gene_synonym="SCE65.30c" FT /product="putative sugar kinase" FT /note="SCE65.30c, probable sugar kinase, len: 326 aa; FT similar to TR:Q9ZFM1 (EMBL:AF098273) Bacillus FT stearothermophilus 2-keto-3-deoxy-gluconate kinase KdgK, FT 314 aa; fasta scores: opt: 598 z-score: 671.6 E(): 4.9e-30; FT 37.0% identity in 308 aa overlap and to SW:KDGK_BACSU FT (EMBL:L47838) Bacillus subtilis FT 2-dehydro-3-deoxygluconokinase (EC 2.7.1.4) KdgK, 324 aa; FT fasta scores: opt: 560 z-score: 629.2 E(): 1.1e-27; 35.4% FT identity in 311 aa overlap. Contains match to Pfam entry FT PF00294 pfkB, pfkB family carbohydrate kinase and match to FT Prosite entry PS00584 pfkB family of carbohydrate kinases FT signature 2" FT /db_xref="GOA:Q9RKE4" FT /db_xref="InterPro:IPR011611" FT /db_xref="UniProtKB/TrEMBL:Q9RKE4" FT /protein_id="CAB61818.1" FT /translation="MTDSRAGLGPQAAGGLLTFGETMGLVTATTIGTLEYARDFTFGIG FT GAESNVAIGAARLGAPVTWIGRVGSDAAGDLVGRRMRAEGIQTVAVRDTSFTGLMVRHH FT RAATVVHVDYHRAGSAGSRLTAHDIPVGEIRRAAILHLTGITPALSASARQATWDAVAA FT AKANGVRVSLDVNHRSKLWDRDTARRELRRLVAEADIVFAGIEEAQLVLDSEADAPESL FT ADALAATGPGETVVKTGARGCTAHIDGAIHEEPALSVPVVDTVGAGDAFVAGYLAEHLR FT GAGPVQRLRTACAMGAYAVSVPGDCELLPTRSELETFLTTGDVLR" FT misc_feature complement(234266..234307) FT /note="PS00584 pfkB family of carbohydrate kinases FT signature 2" FT misc_feature complement(234272..234760) FT /note="Pfam match to entry PF00294 pfkB, pfkB family FT carbohydrate kinase, score 59.00, E-value 1.4e-17" FT CDS complement(235090..235767) FT /transl_table=11 FT /gene="SCO3495" FT /gene_synonym="SCE65.31c" FT /product="putative aldolase" FT /note="SCE65.31c probable aldolase, len: 225 aa; similar to FT TR:AAD35160 (EMBL:AE001693) Thermotoga maritima FT 2-dehydro-3-deoxyphosphogluconate FT aldolase/4-hydroxy-2-oxoglutarate aldolase TM0066, 205 aa; FT fasta scores: opt: 437 z-score: 460.7 E(): 2.8e-18; 39.1% FT identity in 174 aa overlap and to SW:ALKH_BACSU FT (EMBL:L47838) Bacillus subtilis Khg/KdpG aldolase KdgA, 196 FT aa ;fasta scores: opt: 379 z-score: 401.8 E(): 5.3e-15; FT 37.9% identity in 177 aa overlap. Contains match to Pfam FT entry PF01081 Aldolase, KDPG and KHG aldolase" FT /db_xref="GOA:Q9RKE3" FT /db_xref="InterPro:IPR013785" FT /db_xref="UniProtKB/TrEMBL:Q9RKE3" FT /protein_id="CAB61819.1" FT /translation="MTRADDPAPARPECPITTEITSRGLIAILRAPTAEHFPAIAATLL FT DAGIHAIEITLTTHGALRCIRELTAAYGPEAVIGAGTVLTVGQAQTCVDAGARFLVSPV FT AVPDVVRTARAASVAAYPGALTPTEIHAAGRTGAPAVKLFPASAVSPRYVSDLRGPLPG FT IPLIPTGGISLTGIPAWIAAGVAAVGLGTPLIGTAATEGADDHLAARCRQAIAAVSEGR FT AAR" FT misc_feature complement(235135..235722) FT /note="Pfam match to entry PF01081 Aldolase, KDPG and KHG FT aldolase, score 69.00, E-value 9.7e-17" FT CDS complement(236259..237740) FT /transl_table=11 FT /gene="SCO3496" FT /gene_synonym="SCE65.32c" FT /product="putative lyase precursor" FT /note="SCE65.32c, possible lyase precursor, len: 493 aa; FT low similarity to SW:ALYP_PSESO (EMBL:D10336) Pseudomonas FT sp. (strain OS-ALG-9) alginate lyase precursor (EC 4.2.2.3) FT (poly(beta-D-mannuronate) lyase) (poly(ManA) alginate FT lyase) Aly or AlyP, 398 aa; fasta scores: opt: 550 z-score: FT 593.8 E(): 1.1e-25; 29.5% identity in 380 aa overlap. FT Contains possible signal peptide sequence and also a FT Leucine TTA codon, possible target for bldA regulation" FT /db_xref="GOA:Q9RKE2" FT /db_xref="InterPro:IPR012334" FT /db_xref="UniProtKB/TrEMBL:Q9RKE2" FT /protein_id="CAB61820.1" FT /translation="MNRPRLSTYAAITVAAITIAALTTAASALASTGDTSSRTPSGNST FT PQANATIVNVSSSTQLTTAMANAVAGQTIVLANGSYSIGKLNAKNGTSSAPITIMAAQQ FT GKAIITGGQLEVLSSSYVTFSGLKWTNSNTLKITSSHHIRLTRNHFRLTESSSLKWIII FT QGANSHHNRIDHNLFEEKHQLGNFITIDGSSTQQSQYDLIDYNHFRNIGPRATNEMEAI FT RVGWSAISKSDGFTTVENNLFENCDGDPEIVSVKSNANTVRYNTFRTSQGSVSLRHGNR FT SQVHGNFFFGGGKTGTGGVRVYGQDHKIYNNHFEGLTGTGYDAALQLDGGDVDTSGALS FT SHWRVYRATAVHNTFVNNVSNIEIGANYSLAPVDSLVADNIVVGSSGKLFNELKMPKNM FT TYAGNIGWPTGSATIGITTGVRTVNPLLAKQGEVYRLGTGSPAVNTASGSYSFLADDMD FT GQSRSGTADVGADELSTGTVVHKPLNSADVGISAP" FT misc_feature complement(237306..237308) FT /gene="none" FT /note="Leucine TTA codon. Possible target for bldA FT regulation" FT RBS complement(237748..237751) FT CDS complement(238198..238977) FT /transl_table=11 FT /gene="SCO3497" FT /gene_synonym="SCE65.33c" FT /product="putative polyguluronate lyase precursor" FT /note="SCE65.33c, probable polyguluronate lyase precursor, FT len: 259 aa; highly similar to TR:BAA83339 (EMBL:AB030481) FT Corynebacterium sp. ALY-1 polyguluronate lyase precursor FT (EC 4.2.2.11) AlyPG, 256 aa; fasta scores: opt: 1329 FT z-score: 1518.4 E(): 0; 76.9% identity in 260 aa overlap. FT Contains possible N-terminal signal peptide sequence" FT /db_xref="GOA:Q9RKE1" FT /db_xref="InterPro:IPR013320" FT /db_xref="UniProtKB/TrEMBL:Q9RKE1" FT /protein_id="CAB61821.1" FT /translation="MSRTRKRTLATTGVAALSALAALTLPLVTGGTATAAAPCDYPAQQ FT LNLTNWKVTLPTGSSGSPTEVKQPSLATFSASPWFTVNSACTGVQFRSAVNGVTTSGSS FT YARSELREMTSNGTKNASWSATSGTHTMTFREAFNKLPNDKPHVVGAQIHDGDDDVTVF FT RLEGTSLYITKGNDTHHKLVTSNYKLNTVFEGKFVVSGGQIKAYYNGVLQTTIAHSASG FT NYFKAGGYTQANCGNSSPCSSSNYGQVSVYKLLVNHS" FT CDS complement(239026..240102) FT /transl_table=11 FT /gene="SCO3498" FT /gene_synonym="SCE65.34c" FT /product="putative secreted protein" FT /note="SCE65.34c, possible secreted protein, len: 358 aa; FT similar to TR:P94576 (EMBL:Z82987) Bacillus subtilis FT hypothetical 51.5 kD protein YwoF, 468 aa; fasta scores: FT opt: 171 z-score: 188.8 E(): 0.0038; 24.1% identity in 403 FT aa overlap. Contains possible N-terminal region signal FT peptide sequence and Leucine TTA codon, possible target for FT bldA regulation" FT /db_xref="InterPro:IPR012334" FT /db_xref="UniProtKB/TrEMBL:Q9RKE0" FT /protein_id="CAB61822.1" FT /translation="MRLIRYIASAAALLAVTGTSAPVASAAEPRGGHDIYVSPRGSDTN FT PGTRQAPFAGIQRALDVAGPRSTVHLAPGRYLQDFVSRSPGVTLTGPPSAVVQGSGEGR FT AVGEIQHDRVRLTGFTIDGLVGDATEKSDYRKKLLYVMGLTPGDGVDGLRITRMTFRNA FT GEECVRLRYLVTGAEVAHNRITGCGVWDFRFADGGKVGEGIYLGTAPEQQGLNGAPDDR FT PDVSRDNWIHHNRIDTQGNECVDIKENSTANLVERNDCTGQRDPNSAGLDARGSGNTFR FT ANRSYDNVGAGIRVGGDTPADGTGNTIEDNVLLSNSAGGIKFEATPQGRVCGNTLAGNT FT GGDATGTYGNEYEPSRPC" FT misc_feature complement(240061..240063) FT /gene="none" FT /note="Leucine TTA codon. Possible target for bldA FT regulation" FT CDS complement(240099..240686) FT /transl_table=11 FT /gene="SCO3499" FT /gene_synonym="SCE65.35c" FT /product="putative integral membrane protein" FT /note="SCE65.35c, possible integral membrane protein, len: FT 585 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9RKD9" FT /protein_id="CAB61823.1" FT /translation="MKGWERGALRAMEFVAQPALAGAAFCLLALGVVTWLPALAAAAIA FT LQDWRRDGGGRPFTGTLRAFPRCWHALWKDALAASSLIAVLATNCLFLLGRGSATAWVL FT LPVQFALLAALAVYALSLAAAAAVGTDDGFRRRAAVLAFASPRRSLVLLLALLLVPPAM FT LPVPLGPPLLGPTVPLLLALSLHAPLNPRKPA" FT RBS complement(240111..240114) FT RBS complement(240693..240696) FT CDS complement(240697..242739) FT /transl_table=11 FT /gene="SCO3500" FT /gene_synonym="SCE134.01c" FT /gene_synonym="SCE65.36c" FT /product="hypothetical protein" FT /note="SCE134.01c, partial CDS, unknown, len: >671aa;" FT /note="SCE65.36c, unknown (partial CDS), len: >41 aa; FT identical to previously sequenced TR:CAB41199 FT (EMBL:AL049661) Streptomyces coelicolor SCE134.01c" FT /db_xref="UniProtKB/TrEMBL:Q8CJW4" FT /protein_id="CAD55321.1" FT /translation="MLLLEGRLDSLRGDLNGTHAAQWRRLHEQCDWYRRQNPPTEHPEA FT SITYFGPAAANLALAYRLTGQRGYLEEAWRWISTCVAYPHWGRAHMPDHDLDAGWLLHG FT LSLAYSWLGEDLEPERREILRAKLELQGERLHSFAEETTGRWWSSAYWQNHNWICWTGI FT ATAGYALGRSEWTKAARANLETVLTMLPEDGSDSEGVVYWRYGVPWLAIHTDLVQRQEQ FT ADLWSTGGFLRNTTRWRLHQSAPGFEENIDHGDCHDRRSGHSVALYYRLASAYQDGTAQ FT WLGNLVAERHFWREAYESGVRPGVMPEAFLELLWYDPRVTPAAPDREPGTAYFPDLGQI FT TARTGWDSAATCVSFKAAPGGGHRAWDEGHRLKAAGGWDAMSAGHHHPDAGAFVLHSHG FT AFLAVDEGYSNHKRAAHHNLVLVDGEGWADEGRYHVYEGIPEERRARVRDVLAQDGFAH FT ATAESAAMFSERLGVQRVDRTLVVTPLGRVVILDELEAEGPREWTYLLHSDWPTTQLDP FT DGWRLESGPASARLTRLLPTDATATRHRTVVEANPTSSTPSLKVSKAMHTLRLTTPRAR FT TATFLTVLDSTGSLDPRPDPAVLLASDQGHAVSVGQGDEKELVLLAPRARVIETGRVSA FT DAAAIVLSGTRVAAVRARRVDIDGAVALRSDEPFTGVLPTETTGA" FT CDS complement(242746..244431) FT /transl_table=11 FT /gene="SCO3501" FT /gene_synonym="SCE134.02c" FT /product="hypothetical protein" FT /note="SCE134.02c, unknown, len: 561aa;" FT /db_xref="InterPro:IPR012480" FT /db_xref="UniProtKB/TrEMBL:Q9X857" FT /protein_id="CAB41200.1" FT /translation="MELDHGDLLGGVFPAGGAVCRYGCRLDTDAIRGAWTVLAHQKIAR FT HLRHLAAGLPAQRREAVAVLRQYAELYAGLPGTHTGGDDWMLRGRLFHQALTEAIWAVN FT IAHAARTLAAHSDTPGLDEVVPFLQSLREAAGAARGELLRKGEARSNYTAWLAAAEISC FT RCAADLINGAEPDAIGLAQEYGLAAHMRAAVHRDGWEWEASTYYHLFVLHAYLLALRGA FT RPERLPDDLAAALGAMVSALAGVAAPDGTLPALHDGPYRREAQAAEIREVAALATQLFA FT GAPLKSVAQAAERDSAAALSADLDGWFADFPLPATPARHTFPDAGIAVFRSAGVHALLD FT AGPHGGGHGHQDKLSLYLYADDGTAWQPDPGQVPYAHRNLRTYYASTAAHPTFRVDERE FT QQPCDAVLDGDTGRCEQAYDGVTATRRVVTDRSYLLDILVLDAATERRLTAQLRPGTDL FT DVVAQGTDRARTVWGDGESAVLTGHHTSRPQAEFTVVTHPGTADDPARSRQGVDWSLTG FT RRAVFVSVYQSTETAPPIRRVSLSERAVHIDLADGTVAIHPIGA" FT CDS complement(244488..245255) FT /transl_table=11 FT /gene="SCO3502" FT /gene_synonym="SCE134.03c" FT /product="putative 3-oxoacyl-[acyl carrier protein] FT reductase" FT /note="SCE134.03c, possible 3-oxoacyl-[acyl carrier FT protein] reductase, len: 255 aa; similar to many e.g. FT SW:FABG_BACSU 3-oxoacyl-[acyl carrier protein] reductase FT from Bacillus subtilis (246 aa) fasta scores; opt: 522, FT z-score: 518.3, E(): 1.5e-21, (38.1% identity in 247 aa FT overlap). Contains Pfam matches to entries PF00678 FT adh_short_C2, Short chain dehydrogenase/reductase FT C-terminus and PF00106 adh_short, short chain FT dehydrogenase." FT /db_xref="GOA:Q9X858" FT /db_xref="HSSP:1GZ6" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9X858" FT /protein_id="CAB41201.1" FT /translation="MPFDLTGRRALVTGAGHGIGAAIALGLARAGADVIVHHGHSADSA FT ERVVADISALGRKSTAIAADVTDVTAVERLVDESVAFLGGLDIVVVNAGHLVGRVPVAD FT MTEEHFRSVIDVNLVSAFRTCRAALPHVREAGRAGRIILMASQAAHDGGGPGATAYAAA FT KAGVIGFAKGLAKEIGGAGVTVNALAPGYIGDTAFHGTFTAPEAQRGIVGKLPIGRAGT FT VDDVAGTAVYLASGEAGYITGATFDIGGGAWPR" FT misc_feature complement(244512..244604) FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 46.40, FT E-value 6.2e-10." FT misc_feature complement(244668..245234) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 194.70, E-value 1.4e-54." FT CDS complement(245311..246150) FT /transl_table=11 FT /gene="SCO3503" FT /gene_synonym="SCE134.04c" FT /product="putative binding protein dependent transport FT protein" FT /note="SCE134.04c, possible binding protein dependent FT transport protein, len: 279aa; similar to many egs. FT SW:YURM_BACSU hypothetical ABC transporter permease from FT Bacillus subtilis (300 aa) fasta scores; opt: 424, z-score: FT 513.6, E(): 2.7e-21, (32.4% identity in 281 aa overlap) and FT SW:UGPE_ECOLI Sn-glycerol-3-phosphate transport permease FT from Escherichia coli (281 aa) fasta scores; opt: 350, FT z-score: 425.7, E(): 2.1e-16, (29.6% identity in 284 aa FT overlap). Contains Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component." FT /db_xref="GOA:Q9X859" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9X859" FT /protein_id="CAB41202.1" FT /translation="MVLHLALVTVSLVMAIPFLWMIVTSLKTDPDLASYPPGLLPRIWD FT WDNYPEALEYAPFGTYFRNSLFISLGHTALNLALASMAGYALARIPFRGSTVIFMGVLA FT TMMIPTYTKIVPQYLIAKGIPFFGGNDYLGRGGHGWLDSWWGLIIPGALTPFAIFLFRQ FT FYLSLPRELEEAARIDGMGEFGIYARVMTPLVKPAIATVGLLTFESSWNNFLWPLIITT FT DTDLRVIQVGLSAFQQADQNAWAYMMAGTTLATIPMVALFLLAQRYFVQGFANSGIK" FT misc_feature complement(245431..245661) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 68.70, E-value 1.2e-16." FT CDS complement(246227..247210) FT /transl_table=11 FT /gene="SCO3504" FT /gene_synonym="SCE134.05c" FT /product="putative binding protein dependent transport FT protein" FT /note="SCE134.05c, possible binding protein dependent FT transport protein, len: 327aa; similar to many egs. FT SW:YURN_BACSU hypothetical ABC transporter permease from FT Bacillus subtilis (292 aa) fasta scores; opt: 586, z-score: FT 707.9, E(): 4.1e-32, (32.4% identity in 287 aa overlap) and FT SW:UGPA_ECOLI Sn-glycerol-3-phosphate transport permease FT from Escherichia coli (295 aa) fasta scores; opt: 583, FT z-score: 704.3, E(): 6.5e-32, (33.8% identity in 290 aa FT overlap). Contains Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component and Prosite match to PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp signature." FT /db_xref="GOA:Q9X860" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9X860" FT /protein_id="CAB41203.1" FT /translation="MPSHPAVDTTRPHAPIVHRSTDSSVPHRERPQRRRKFGRERRRVA FT LLLLAPSLVHLVWWIGLPVVATFALAFTDYDILAGTVTFNGLDNFQEIFSDPTWNASIW FT HTVVFTFFTVPVAMVIAVVLALLLNVKMRGAAWYRTAVFLPHVTATVAIALVWMWMFEP FT RLGVVNTMLGWIGIDGPVWLADPDWALTAVIVVSIWKGIGIKMLIYLAALQAMPNDVYE FT AARIDGASQVRQFFSITLPLLKPATFFVLVVSIIDSFQAFDQLYVLTPDGGPGNSTTVM FT TYEIYRTAFKEFNMGAACAQSVVLFAFLLVLMLISRRLTGKEDDVR" FT misc_feature complement(246341..246577) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 73.20, E-value 5.4e-18." FT misc_feature complement(246488..246574) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp signature." FT CDS complement(247215..248504) FT /transl_table=11 FT /gene="SCO3505" FT /gene_synonym="SCE134.06c" FT /product="putative secreted substrate binding protein" FT /note="SCE134.06c, possible secreted substrate binding FT protein, len: 429aa; weak similarity to many egs. TR:O87856 FT (EMBL:AL031013) putative secreted sugar binding protein FT from Streptomyces coelicolor (438 aa) fasta scores; opt: FT 368, z-score: 408.8, E(): 1.9e-15, (26.2% identity in 428 FT aa overlap) and SW:MALE_ECOLI maltose-binding protein from FT Escherichia coli (396 aa) fasta scores; opt: 188, z-score: FT 211.5, E(): 0.00018, (23.0% identity in 374 aa overlap). FT Contains probable N-terminal signal sequence and Prosite FT match to PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site." FT /db_xref="GOA:Q9X861" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q9X861" FT /protein_id="CAB41204.1" FT /translation="MRPRTSPLSRRRLLGLGAATAAGAALSACGGPAPQKGGGGDASLR FT LLTPIFDRADGQKLLTSLLADFKKDHPGVSVQVDYTEYGKLNEKLATSIVGGQPYDVML FT MGVGWIPPFVEKGVLADLGTSQSELDRLYNPRVVQPGVYEGKTYARPILLDTRMGIYRK FT DILADAGIDAPPKDLTELKEMAKELTVREGGKLTRAGVDILSNDLRQTYLPVMWAHGAD FT LFTDGKPVFDSAEAVDALQWMVDIIRTEKIEDYGFTQKGAVVAPLVQGRAAMMVGHNDM FT WRQVSESAPELIAEDKIAGFMLNQQRPALFQGGTLATLSAKTRYPDQAKSLVEFLSGEK FT VSPQAAEQRGNIPAVLSAADSDYVRSNKLVSFAVDNLDHAFSEGGVPTWLEIREEFKPA FT LESALLGKSSPADALRGLAEKAEAIIAKGA" FT misc_feature complement(248418..248450) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site." FT CDS 248665..249726 FT /transl_table=11 FT /gene="SCO3506" FT /gene_synonym="SCE134.07" FT /product="putative lacI-family transcriptional regulator" FT /note="SCE134.07, possible lacI-family transcriptional FT regulator, len: 353 aa; similar to many e.g. SW:MALR_STRCO FT maltose operon transcriptional repressor MalR from FT Streptomyces coelicolor (344 aa) fasta scores; opt: 440, FT z-score: 508.9, E(): 4.9e-21, (32.4% identity in 352 aa FT overlap). Contains Pfam matches to entries PF00356 lacI, FT Bacterial regulatory proteins, lacI family and PF00532 FT Peripla_BP_like, Periplasmic binding proteins and LacI FT family." FT /db_xref="GOA:Q9X862" FT /db_xref="HSSP:1LQC" FT /db_xref="InterPro:IPR001761" FT /db_xref="UniProtKB/TrEMBL:Q9X862" FT /protein_id="CAB41205.1" FT /translation="MAGVTIYQVAEEAGVSPSTVSNLLNGRTGKMLPETRSRVESAIRR FT LGYRPNRAAQQLRTGRIQMLGLIVPSVANPFWGTFARHLEAAALAEGFYMLLCNSERDP FT ERERRYVEELWGDGIGGVVLCSSLPSLDHVKPTVEAGLGLVAFDRTAQPGDPHRAVNIG FT TDNVLGMRLATEHLLALGHTRLAFVSGSIGSINRAERYSGFQQAIEAAGLPPEAGVVWS FT GADTVDFDDRDTAELGRVAALEILSSPHPPTAIVAINDMCALGIVAGTREAGLVVGRDV FT SVTGYDDIMLAGMAMPALTTVRQPVEEMAATAFAKLRQVMDGGGGETGQSILHRPALVV FT RDSTSAPAMSPVV" FT misc_feature 248668..248751 FT /note="Pfam match to entry PF00356 lacI, Bacterial FT regulatory proteins, lacI family, score 29.40, E-value FT 9.5e-07." FT misc_feature 248845..249603 FT /note="Pfam match to entry PF00532 Peripla_BP_like, FT Periplasmic binding proteins and LacI family., score 94.40, FT E-value 2.3e-24." FT CDS 249811..251313 FT /transl_table=11 FT /gene="SCO3507" FT /gene_synonym="SCE134.08" FT /product="putative integral membrane efflux protein" FT /note="SCE134.08, possible integral membrane efflux FT protein, len: 500aa; similar to many mostly involved in FT antibiotic efflux eg. TR:Q50396 (EMBL:U46844) from the FT ethambutol resistance gene cluster of Mycobacterium FT tuberculosis (412 aa) fasta scores; opt: 780, z-score: FT 854.0, E(): 0, (36.7% identity in 401 aa overlap). Contains FT several possible membrane spanning hydrophobic regions." FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9X863" FT /protein_id="CAB41206.1" FT /translation="MVGRAIADGRARPSADRSTRTVVVFGGAGAAHRNNSRRTRRTTTR FT RRARLSTEPGTGSAPTPDTRDSFGTLSPRAPLLSALKVGNYRLFFLGQVVSNNGTWTQR FT IAQDWLVLSLTGSSTAVGITTALQFLPLLLFGLYGGVLVDRLPKRPILLATQVAMALTA FT LALAVLTLTGRVHVLHVYAAAFAVGLATVLDNPARQSFLSELVGPELLRNAVGLNSANF FT QSARLIGPALAGLLITGVGTGWAFLLNGVSFAAPLACMLLMRSRELHAVERAPRGKGQL FT REGLRYVAGRPDLVWPIVLVGFFGTFALNFPVHLSAFADDVFDAGAGAYSLFNTLVAAG FT SLTGALLAARHEATRRRLPFLAALAFGVLQAVAAVAPTLWSFALLMVPMGLFAMVVNVT FT TNATMQTSTAPAVRGRVTALYMMVLLGGAPLGAPVVGWITDTYGARAGLAAAGAVAAVT FT ATVTGLFLVRAGGHRLAVGWSHPLPRIRIEPRKTSKGADLPT" FT CDS 252241..252678 FT /transl_table=11 FT /gene="SCO3508" FT /gene_synonym="SCE134.09" FT /product="putative maturase-related protein" FT /note="SCE134.09, possible maturase-related protein, len: FT 145aa; similar to many proposed maturase-related protein FT from prokaryotes eg. TR:O53616 (EMBL:AL021428) putative FT maturase homolog from Mycobacterium tuberculosis (235 aa) FT fasta scores; opt: 251, z-score: 315.3, E(): 3e-10, (56.9% FT identity in 72 aa overlap)." FT /db_xref="UniProtKB/TrEMBL:Q9X864" FT /protein_id="CAB41207.1" FT /translation="MNTDELEHRRFDDLFSLVADPGFLLVAWDLVRGNKGASAAGVDGS FT TASSIALWVGVEKFLDMLRSQIKDRSFQPMPVRERMIPKAGGKLRRLGIATITDRVVQA FT SLKLARFGEAAPGKRTGRKTGTAPRADFTPAIGCAFRYSPV" FT CDS 252747..253709 FT /transl_table=11 FT /gene="SCO3509" FT /gene_synonym="SCE134.10" FT /product="conserved hypothetical protein" FT /note="SCE134.10, unknown, len: 320 aa; weakly similar to FT SW:YD75_HAEIN hypothetical protein from Haemophilus FT influenzae (302 aa) fasta scores; opt: 308, z-score: 377.0, FT E(): 1.1e-13, (23.6% identity in 301 aa overlap) and FT similar to TR:Q9L1X0 (EMBL:AL138667) Streptomyces FT coelicolor hypothetical protein SC3D9.09, 350 aa; fasta FT scores: opt: 589 Z-score: 696.5 E(): 3.6e-31; 46.006% FT identity in 313 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9X865" FT /protein_id="CAB41208.1" FT /translation="MQRSREGALVAELMMFRRDSDGRDVELSSSTVALEVELQRRVEAG FT LEQMLGVRFLASEYPTGPWHRGRIDTLGLDENGSPVVIEFKKGSDSGVMSQAVSYLSWL FT ESAHHEFEALVRKVLGAEAAESVDWRRPRMICIAAGFSHHDRVAVQRLPERIDLVRYRI FT FDGGLLGLLLVDSATGFPSAASSRRVRERAPVVDSVPTASVVSPSAGGGAVPECLRDLY FT AELDEALTAWGEVEVASLRHYIAYRRLVNVASVIFRPKHEAILMYLRLDPDTVELEEGF FT TRDMRGIGHLGTGDLEVRIVSAADLEKAAPLIRRAFEAA" FT stem_loop 253718..253763 FT /note="Perfect 20 base inverted repeat with 6 base loop." FT CDS complement(253807..254553) FT /transl_table=11 FT /gene="SCO3510" FT /gene_synonym="SCE134.11c" FT /product="putative DNA methylase" FT /note="SCE134.11c, possible DNA methylase, len: 248 aa; FT similar to many e.g. TR:O68789 (EMBL:AF053947) adenine FT methyltransferase homolog from Yersinia pestis (213 aa) FT fasta scores; opt: 246, z-score: 300.2, E(): 2.1e-09, FT (30.8% identity in 224 aa overlap). Contains Prosite match FT to PS00092 N-6 Adenine-specific DNA methylases signature." FT /db_xref="GOA:Q9X866" FT /db_xref="HSSP:1G60" FT /db_xref="InterPro:IPR002941" FT /db_xref="UniProtKB/TrEMBL:Q9X866" FT /protein_id="CAB41209.1" FT /translation="MSYTLHRGDALTVLKSLPDESVQAVITDPPYNSGGRTSSDRTGRT FT ARAKYVTSNSAHDLANFPGENRDQRSYRSWLTELLTEAYRASTEHAVTMVFTDWRQEPT FT TSDALQMAGWTWSGTIPWIKPSSRPRKGGPKQDSEFIIWGVKGSLDNTRDLYLPGHYIA FT SQPRKGRVHITQKPVEVMQQLVQVCPEGGTVLDPFTGSGSTGVAALREGRHFVGVELSA FT HYADVAEERLRAELTKDDFELAGPEA" FT misc_feature complement(254461..254481) FT /note="PS00092 N-6 Adenine-specific DNA methylases FT signature." FT CDS 255133..256278 FT /transl_table=11 FT /gene="SCO3511" FT /gene_synonym="SCE134.12" FT /product="putative lipoprotein" FT /note="SCE134.12, possible lipoprotein, len: 381aa; similar FT to many, mostly hypotheticals, eg. TR:P71594 (EMBL:Z80233) FT hypothetical protein from Mycobacterium tuberculosis (281 FT aa) fasta scores; opt: 288, z-score: 295.1, E(): 4e-09, FT (40.9% identity in 132 aa overlap). Also similar to FT SW:SPR_ECOLI lipoprotein Spr precusror from Escherichia FT coli (188 aa) fasta scores; opt: 201, z-score: 211.7, E(): FT 0.00018, (37.2% identity in 113 aa overlap). Contains a FT possible N-terminal signal sequence and Prosite match to FT PS00013 Prokaryotic membrane lipoprotein lipid attachment FT site. Also contains Pfam match to entry PF00877 NLPC_P60, FT NLP/P60 family domain of unknown function." FT /db_xref="InterPro:IPR000064" FT /db_xref="UniProtKB/TrEMBL:Q9X867" FT /protein_id="CAB41210.1" FT /translation="MKKTTGALVGLCATGPLLLALPILGIGAGTASASCSTDGAQGVDA FT SAVAKQVKTILDGGDRGSVSVPGLDAPADQVPNAKTIQATGVAMNLPARGQAVALATAL FT QESGLRNLTYGDRDSLGLFQQRPSMGWGTASQILDPVHASTKFYEGLKKVSGWQSLSVT FT QAAQAVQKSGFPEAYAKWEPLATALQKAIEPLLQEAGGASPSPSPSGSADTGSPSPDSA FT GGCSADGDGTDFGTIPAGALPDEYKIPASAPPKVQTAIRWALGQLGSPYQWGGTCTDSH FT GKNPMGRCDCSSLMQGAYKAAGVTLTRTTYTQVKDGKAVSVAALKPGDLLFTEGTAAVP FT EHVGMAIGQGLIVHAPHTGDVVRITTVASWKSRILAARRVV" FT misc_feature 255205..255237 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site." FT misc_feature 255919..256272 FT /note="Pfam match to entry PF00877 NLPC_P60, NLP/P60 FT family, score 96.80, E-value 4.1e-25." FT CDS 256367..256675 FT /transl_table=11 FT /gene="SCO3512" FT /gene_synonym="SCE134.13" FT /product="putative integral membrane protein" FT /note="SCE134.13, possible integral membrane protein, len: FT 102 aa; similar to TR:Q9L1N2 (EMBL:AL138977) Streptomyces FT coelicolor putative membrane protein SC7F9.35c, 104 aa; FT fasta scores: opt: 545 Z-score: 647.4 E(): 2e-28; 79.412% FT identity in 102 aa overlap. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9X868" FT /protein_id="CAB41211.1" FT /translation="MYLAEQVIQLAYDPGIKPNEGGLPGLNVLKQVMGSINLFGLIAVV FT GALAVSAGVWAWGHHSGGHQAEANGKKGVLVSAGAALLLGAANGVVAFFSTLGTQVH" FT CDS 256675..257355 FT /transl_table=11 FT /gene="SCO3513" FT /gene_synonym="SCE134.14" FT /product="putative secreted protein" FT /note="SCE134.14, possible secreted protein, len: 226 aa. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="UniProtKB/TrEMBL:Q9X869" FT /protein_id="CAB41212.1" FT /translation="MAQHSTHPGGASRVRRRALLGTAVLAVLVALAGLAAYLTREGRSP FT SDTASPPPSSPTASSSHAAPPGPHTRPRALPVPPKTHDPITYGKAAAAALWSYDTRAYS FT QPELRKALRGWLTTESNYADLASVDQAIPSAVLWKEMAANKQVATAKINEGHFPHAFTQ FT ALQDNPGAITEAYVYAVTVSGKQSIRWKGSAAGGAESRSTTLAVQCRPNHPCALVGVMP FT SVAP" FT CDS 257383..258792 FT /transl_table=11 FT /gene="SCO3514" FT /gene_synonym="SCE134.15" FT /product="putative ATP-binding protein" FT /note="SCE134.15, possible integral membrane ATP-binding FT protein, len: 469aa; contains Prosite match to PS00017 FT ATP/GTP-binding site motif A (P-loop). Also contains FT possible membrane spanning hydrophobic regions." FT /db_xref="GOA:Q9X870" FT /db_xref="UniProtKB/TrEMBL:Q9X870" FT /protein_id="CAB41213.1" FT /translation="MGVCDFPLMDKVCGAVDFATNPAGTVTDGLGAWIAKSAGELASSA FT ADLAAKAVNKTTAIDLNAGWFRDNYELLLPIGLALTVGIFCIQLMTAAWRRDERALAKA FT AFGTMTGVLFSFSAIAFTTVAITVVDALSDGLFKAANTSIDDAIRRVIKVDQMGAMYGL FT GWGVPSLVAFGCAIGAFLYWGVMVARKVGVLIMVALAVFAGAGGGWEVAKRWRRGWIEA FT TGTLIVSKLLMTVVFLIGVSAMGKTDASDGMSALSDAMAGIVVMVLVLLCPYATYKFVH FT WASDGGGHDDMHRTGVAGMAVAAGAAKTAGSLALRAGTGAPAPQGPNQVPGAGTDGVAS FT GINPSGGNLSKEGIDAGPPKQQTRFRYGEDPNASGDKGRALIQRPGIPPLITRPGEDEP FT EGSESTAQGVAGGSGHLTGASAPGGDMTSMPPADPGPSASGTPASASGPSATGSATPTN FT WVYPTQPPSGS" FT misc_feature 258100..258123 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 258924..260390 FT /transl_table=11 FT /gene="SCO3515" FT /gene_synonym="SCE134.16" FT /product="putative integral membrane protein" FT /note="SCE134.16, possible integral membrane protein, len: FT 488aa; contains a possible membrane spanning hydrophobic FT region." FT /db_xref="UniProtKB/TrEMBL:Q9X871" FT /protein_id="CAB41214.1" FT /translation="MSGKHQSSTPTVKFPHRSRRGVLLGLSVPQLAVAGLTGLLLLAVI FT LARGVVGALQLIPLWAVIALLVFVRHRGRALADWAPIVVRYALRRMRGQLVWLTRPSRR FT PTREGLLHLPGTAASLRVTTAPDGKYGAVHNPHTGTLTAVVKISSRAYALLDSGTQQAN FT VGGWGRALAALARTGQIARIQVIERTIPDSGDALRRYWEEHGRPDTPMAGAIYNELIQS FT AGPAAAPHEAYVAVSLDTKATRRLINQAGGGLTGAFSVLAQLTSTFDQAARTAGLTPTG FT WLTAREIAAVVRTSYDPKALATLDRWSTAGRPEAEPAAAGPVVVVEKADHIATDSAVHA FT TYWVENWPRTETSAGFLHQLLFTGGVRRTLSLSYEPKNLDAALRDVQRKKSSVIADAAE FT RARRGQVDSEADSIEYQDIKSRERQLIAGYADVALTGLLTVSADTEDELRTACAVVETA FT AVGAQLDLRPLTWQQAEAFTAAALPLALAA" FT CDS 260417..260869 FT /transl_table=11 FT /gene="SCO3516" FT /gene_synonym="SCE134.17" FT /product="hypothetical protein" FT /note="SCE134.17, unknown, len: 150aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X872" FT /protein_id="CAB41215.1" FT /translation="MSRTASPTAQDFVPFATAALDFHQALNIPCGPLVTTRAELDALHA FT HLVSLYGLLDAHAGRTGQLVANEGDQLRTARTRIWQAAEHLHAAYHAAPRPDSSEIPEP FT EACQAGLPEGAPELTICQRHQRTAHLVRRRTTPADLHAPFTGLVRR" FT CDS 260932..262401 FT /transl_table=11 FT /gene="SCO3517" FT /gene_synonym="SCE134.18" FT /product="putative ATP-binding protein" FT /note="SCE134.18, possible ATP-binding protein, len: 489aa; FT contains Prosite match to PS00017 ATP/GTP-binding site FT motif A (P-loop). Similar to TR:Q9L1N7 (EMBL:AL138977) from FT Streptomyces coelicolor (507 aa) fasta scores; opt: 2405, FT Z-score: 2578.8, 73.469% identity (75.000% ungapped) in 490 FT aa overlap." FT /db_xref="GOA:Q9X873" FT /db_xref="UniProtKB/TrEMBL:Q9X873" FT /protein_id="CAB41216.1" FT /translation="MPRKTTRAEQRAARAGFTEARRQARLAGNPPKHRAEQTLDPDLRP FT TYPLAGRPGPASARGGKLDLPAHRMTTATASGAYPFVAEGGLGAEGVFIGRDVHAEAAF FT CFDPFSLYNSGRVEGFTNPNAVLAGIIGMGKSALAKSIATRSIAHGYRIYIPCDPKGEW FT TAVSQALGGYSIALGPGLPGRLNPLDAPARPASVSEEDWFTEVRKRRLLLLAGLARTVL FT KRDLRPMEHTALDLALDLVVADAAARGTVPLLGEIAHVLGSPERLDQALGHQAGHLGSA FT AQDLAHALRRLVHGDLSGMFDAPSTVSFDPTTPMLSIDLSRLGGSGDDTALVLAMTCAS FT AWMESALSDPDGGRRWVIYDEAWRLMRHVGLLERMQSQWKLSRGLGIANLMVIHRLSDL FT LSAGDAGSRGRVLAEGLLADCSTRIIYRQEPDQLAAAASLLGLTGVETQAVSALTKGRG FT LWKVAGRSFITQHILHPAERELFDTDARMAA" FT misc_feature 261316..261339 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 262494..263129 FT /transl_table=11 FT /gene="SCO3518" FT /gene_synonym="SCE134.19" FT /product="hypothetical protein" FT /note="SCE134.19, unknown, len: aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X874" FT /protein_id="CAB41217.1" FT /translation="MAWRRHLPALASAAAGINEACDAWDAVSDSLCDADGWPLDDKVYG FT GGKVKRDAEAWKHAEVFLDHGPEVLAGVRAAADGPDYVEGPISDDLRRIRGIDTTLFRA FT QELRHEWADVMALMDGSQPSVLHLYKERAEEHRNTEGRHYSHELGSKGPALVRVGEYLA FT HRADTERPTQTERARVALTRSTHNTPGVSPASPQLPPASQPPAPGRSR" FT CDS 263260..263871 FT /transl_table=11 FT /gene="SCO3519" FT /gene_synonym="SCE134.20" FT /product="hypothetical protein" FT /note="SCE134.20, unknown, len: 203aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X875" FT /protein_id="CAB41218.1" FT /translation="MHHKTSPPTARSDPRPIQAALCSALGQRGLESTVEYGLSDYIVHA FT ELPDGSSLIISPPQEPPSEHPESPEGWMVTRHRSAEPAVYEVIYDSEPDGPHARHGGSV FT PDLLSAVDARLDQLDVPPRQEQERSSKARAATVLPPDSAPSRASVALASSPSVGQRVLP FT TGPPPGAFRAGRAAVGQFLIRPPALTDRDPGVLRARHSQN" FT CDS 263922..264686 FT /transl_table=11 FT /gene="SCO3520" FT /gene_synonym="SCE2.01" FT /gene_synonym="SCE134.21" FT /product="hypothetical protein" FT /note="SCE2.01, unknown, len: 254aa;" FT /note="SCE134.21, partial CDS, unknown, len: >203aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X896" FT /protein_id="CAB41060.1" FT /translation="MPSHYDVLPDLAFGHHPVHGIVAANPKNLAASTWMLKGFDFHPVP FT DQPTLYALADQNRDGHGRTSRAIELLRKAGYQVDVDAALDPAPAPETAQVRDRGPLGEP FT DVAFADHPQLGIVAALDDRVSGLSGLALVEDGWRHNSSLDIYTLPATTDRVEALGKVAD FT ATVALHRSGLQVAVQPCLAQEVTARPRPAGTPTAGRERGRGPARASPLSAAALAASPAR FT AGIPGRAPVPASAVITAAVRPVDPRIAYSRDR" FT CDS complement(264802..265506) FT /transl_table=11 FT /gene="SCO3521" FT /gene_synonym="SCE2.02c" FT /product="putative integral membrane protein" FT /note="SCE2.02c, possible integral membrane protein, len: FT 234 aa; similar to TR:P96876 (EMBL:Z92771) hypothetical FT protein from Mycobacterium tuberculosis (222 aa) fasta FT scores; opt: 357, z-score: 430.7, E(): 1.1e-16, (33.8% FT identity in 195 aa overlap). Contains possible membrane FT spanning hydrophobic regions" FT /db_xref="GOA:Q9X897" FT /db_xref="InterPro:IPR002524" FT /db_xref="UniProtKB/TrEMBL:Q9X897" FT /protein_id="CAB41061.1" FT /translation="MTAISLGPSPARRDLLTRRIRLLVAATIIYNVIEAIVAITAGTIA FT SSTALIGFGLDSVIEVSSAAAVAWQFSAHDHATRDAREQRTLRIIAASFFALALYVSID FT SVRALTGTGEADHSLPGIVLATLSLAIMPFLSAAQRKTGRELGSASAVADSKQTLLCTY FT LSAVLLVGLLANLLLGWSWADPIAALVIAALAVKEGRDAWQGKGCCAPTTGHEPAASDG FT DACGCATGCSCC" FT CDS complement(265507..265842) FT /transl_table=11 FT /gene="SCO3522" FT /gene_synonym="SCE2.03c" FT /product="putative transcriptional regulator" FT /note="SCE2.03c, possible transcriptional regulator, len: FT 111aa; similar to many egs. SW:YW25_MYCTU hypothetical FT transcriptional regulator from Mycobacterium tuberculosis FT (118 aa) fasta scores; opt: 348, z-score: 457.9, E(): FT 3.4e-18, (52.9% identity in 102 aa overlap) and FT SW:ARSR_STAXY arsenical ersistance operon repressor from FT Staphylococcus xylosus plasmid pSX267 (104 aa) fasta FT scores; opt: 126, z-score: 176.8, E(): 0.016, (30.4% FT identity in 102 aa overlap). Contains Pfam match to entry FT PF01022 HTH_5, Bacterial regulatory protein, arsR family." FT /db_xref="GOA:Q9X898" FT /db_xref="HSSP:1SMT" FT /db_xref="InterPro:IPR001845" FT /db_xref="UniProtKB/TrEMBL:Q9X898" FT /protein_id="CAB41062.1" FT /translation="MLTLAADIDVLARFGRALADPIRCRILLALRQAPAYPADLADSLG FT ISRTRLSNHLACLRDCGLVVTVPDGRRTRYELADERLGHALDDLRAAVVAVEADRTCAD FT ADEKGCC" FT misc_feature complement(265567..265800) FT /note="Pfam match to entry PF01022 HTH_5, Bacterial FT regulatory protein, arsR family, score 64.90, E-value FT 1.7e-15." FT CDS 266154..266879 FT /transl_table=11 FT /gene="SCO3523" FT /gene_synonym="SCE2.04" FT /product="hypothetical protein" FT /note="SCE2.04, unknown, len: 241aa;" FT /db_xref=" |