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EBI DbfetchID AL939115; SV 1; linear; genomic DNA; STD; PRO; 276800 BP. XX AC AL939115; AL035640; AL035654; AL035707; AL049573; AL132674; AL354048; AC AL355832; AL359989; AL442120; AL596138; XX DT 25-OCT-2002 (Rel. 73, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 5) XX DE Streptomyces coelicolor A3(2) complete genome; segment 12/29 XX KW . XX OS Streptomyces coelicolor OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Streptomycineae; Streptomycetaceae; Streptomyces. XX RN [1] RP 1-276800 RA Bentley S.D.; RT ; RL Submitted (09-MAY-2002) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Streptomyces sequencing team, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL sdb@sanger.ac.uk XX RN [2] RX DOI; 10.1038/417141a RX PUBMED; 12000953. RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L., RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H., RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E., RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D., RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.; RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor RT A3(2)"; RL Nature 417(6885):141-147(2002). XX DR EMBL-CON; AL645882. DR RFAM; RF00379; ydaO-yuaA. XX FH Key Location/Qualifiers FH FT source 1..276800 FT /organism="Streptomyces coelicolor" FT /strain="A3(2)" FT /mol_type="genomic DNA" FT /db_xref="taxon:1902" FT stem_loop 48..98 FT /note="Score 59: 21/22 ( 95%) matches, 0 gaps" FT CDS complement(146..652) FT /transl_table=11 FT /gene="SCO3054" FT /gene_synonym="SCBAC19G2.09c" FT /product="conserved hypothetical protein" FT /note="SCBAC19G2.09c, conserved hypothetical protein, len: FT 168aa: similar to many in Streptomyces coelicolor eg. FT TR:Q9F2X0 (EMBL:AL392148) SCD20.09 hypothetical protein FT (190 aa) fasta scores; opt: 250, Z-score: 285.6, 34.503% FT identity (38.816% ungapped) in 171 aa overlap." FT /db_xref="InterPro:IPR010852" FT /db_xref="UniProtKB/TrEMBL:Q93J49" FT /protein_id="CAC44519.1" FT /translation="MSERSPAPGGLGLVETLVNTLDLETGADSLDTEEGRAPPGLTEDD FT VPAARELRESLRATLLAHAGHPPHRAVTPLGELLAAAPLVVAVDPADGSAALAPAGEGS FT LTARVAAAVAQALVAGTWSRLKACEAADCHWAYYDRSPAGRGRWCSMQVCGARAKMRRY FT RAKES" FT CDS 764..1123 FT /transl_table=11 FT /gene="SCO3055" FT /gene_synonym="SCBAC19G2.10" FT /product="conserved hypothetical protein" FT /note="SCBAC19G2.10, conserved hypothetical protein, len: FT 119aa: similar to many in Streptomyces coelicolor e.g. FT TR:O85701 (EMBL:AF072709) 3SCF60.11c conserved hypothetical FT protein (131 aa) fasta scores; opt: 322, Z-score: 387.9, FT 42.017% identity in 119 aa overlap and downstream FT neighbouring CDS SCBAC19G2.11" FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/TrEMBL:Q93J48" FT /protein_id="CAC44520.1" FT /translation="MPVAELGPVVLDCPDPRALARFYADVLGGTVEGEGDWVDLRLPGG FT RALAFQAAPGFVPPKWPAPDDSQQFHLDLDVKDLDAAEKAVLELGARPLDAEDRTGTFR FT VYADPAGHPFCLCAC" FT repeat_region 786..1114 FT /note="Directly repeated at 11832..12181" FT CDS 1153..1545 FT /transl_table=11 FT /gene="SCO3056" FT /gene_synonym="SCBAC19G2.11" FT /product="conserved hypothetical protein" FT /note="SCBAC19G2.11, conserved hypothetical protein, len: FT aa: similar to many in Streptomyces coelicolor eg. FT TR:Q9F3E9 (EMBL:AL450289) SC2H2.06 hypothetical protein FT (150 aa) fasta scores; opt: 340, Z-score: 415.4, 46.032% FT identity in 126 aa overlap and upstream neighbouring CDS FT SCBAC19G2.10" FT /db_xref="UniProtKB/TrEMBL:Q93J47" FT /protein_id="CAC44521.1" FT /translation="MAPAARFRSVVVDCPDPRELARFYAAVGGGTPDEADPDWVVLQVP FT GGPRLSFQRAPDLTPPEWPRSDRNAQQFHLDFDGGATWAEMDAAHDRVLALGARPLDLE FT DREDKDFMVYADPAGHPFCLCRIEHT" FT repeat_region 1178..1527 FT /note="Directly repeated at 11440..11768" FT CDS complement(1558..2688) FT /transl_table=11 FT /gene="SCO3057" FT /gene_synonym="SCBAC19G2.12c" FT /product="putative dipeptidase" FT /note="SCBAC19G2.12c, possible dipeptidase, len: 376 aa: FT similar to many eukaryotic peptidases e.g. SW:P31430 FT (MDP1_RAT) rat renal dipeptidase (410 aa) fasta scores; FT opt: 440, Z-score: 474.0, 36.056% identity (38.906% FT ungapped) in 355 aa overlap. Also weakly similar to FT TR:Q9KH70 (EMBL:AF268476) thermostable dipeptidase from FT Brevibacillus borstelensis (307 aa) fasta scores; opt: 273, FT Z-score: 298.4, 28.159% identity (30.116% ungapped) in 277 FT aa overlap. Contains Pfam match to entry PF01244 FT Renal_dipeptase, Renal dipeptidase. Also similar to FT neighbouring upstream CDS SCBAC19G2.13c" FT /db_xref="GOA:Q93J46" FT /db_xref="HSSP:1ITU" FT /db_xref="InterPro:IPR008257" FT /db_xref="UniProtKB/TrEMBL:Q93J46" FT /protein_id="CAC44522.1" FT /translation="MADLQDDLHTGTEAGGLDDLPVPLAAEAFPPEPYAPVSDPDDEPL FT ARAHAVLAAHPVADGCNGLPWALRHLPWYDLELGESAVDTDVPRLREGHVGALLWSLHL FT PESLDGDRAVGATLEQLDLVKTVVRAHPEGLRLAYDAGQAIDARNCGRIAVLPGPAGAA FT ALGDRLGILRSLHALGLRVLTLSGVSWASEAGLTRFGEEVVREMNRLGVVADLSGASAE FT TVRRTFAVSKAPALCTRSAARALRPHPANLPDDLLVELGAAGGLCMVPLTAEQTGPTVR FT DVADHLDHVRTVAGPQSVGLSGTYDSGAAHPLELGDPSCYPRLVAELLRRGWDEADVAL FT LTWGNVQRVLRAAAFTAKAAQLRREPSTATIADLDG" FT misc_feature complement(1561..2616) FT /note="Pfam match to entry PF01244 Renal_dipeptase, Renal FT dipeptidase, score 121.70, E-value 1.4e-32" FT repeat_region complement(1562..2643) FT /note="Degenerately, directly repeated at 13490..14610" FT CDS complement(2808..4010) FT /transl_table=11 FT /gene="SCO3058" FT /gene_synonym="SCBAC19G2.13c" FT /product="putative dipeptidase" FT /note="SCBAC19G2.13c, possible dipeptidase, len: 400 aa: FT similar to many eukaryotic peptidases e.g. SW:P31429 FT (MDP1_RABIT) rabbit renal dipeptidase (410 aa) fasta FT scores; opt: 788, Z-score: 879.1, 42.432% identity FT (48.580% ungapped) in 403 aa overlap. Also weakly similar FT to TR:Q9KH70 (EMBL:AF268476) thermostable dipeptidase from FT Brevibacillus borstelensis (307 aa) fasta scores; opt: 450, FT Z-score: 506.1, 31.034% identity (36.486% ungapped) in 348 FT aa overlap. Contains Pfam match to entry PF01244 FT Renal_dipeptase, Renal dipeptidase. Also similar to FT neighbouring downstream CDS SCBAC19G2.12c" FT /db_xref="GOA:Q93J45" FT /db_xref="HSSP:1ITU" FT /db_xref="InterPro:IPR008257" FT /db_xref="UniProtKB/TrEMBL:Q93J45" FT /protein_id="CAC44523.1" FT /translation="MTSLEKARELLREFPVVDGHNDLPWALREQVRYDLDARDIAADQS FT AHLHTDLARLRSGGVGAQYWSVYVRSDLPGAVTATLEQIDCVRRLIDRHPGELRAALTA FT ADMEAARAEGRIASLMGAEGGHSIDNSLATLRALYALGVRYMTLTHNDNNAWADSATDE FT PGVGGLSAFGREVVREMNREGMLVDLSHVAATTMRDALDTSTAPVIFSHSSSRAVCDHP FT RNIPDDVLERLSANGGMAMVTFVPKFVLQAAVDWTAEADDNMRAHGFHHLDSSPEAMKV FT HAAFEERVPRPVATVSTVADHLDHMREVAGVDHLGIGGDYDGTPFTPDGLGDVSGYPNL FT IAELLDRGWSQSDLAKLTWKNAVRVLDAAEDVSRGLRAARGPSNATIEQLDGTAAEQPE FT G" FT misc_feature complement(2820..4010) FT /note="Pfam match to entry PF01244 Renal_dipeptase, Renal FT dipeptidase, score 280.40, E-value 2.3e-80" FT repeat_region complement(2836..3956) FT /note="Degenerately, directly repeated at 12216..13297" FT CDS complement(4025..4567) FT /transl_table=11 FT /gene="SCO3059" FT /gene_synonym="purE" FT /gene_synonym="SCBAC19G2.14c" FT /product="phosphoribosylaminoimidazole carboxylase FT catalytic subunit PurE" FT /EC_number="4.1.1.21" FT /note="SCBAC19G2.14c, phosphoribosylaminoimidazole FT carboxylase catalytic subunit PurE, len: 180aa: strongly FT similar to many eg. SW:Q44679 (PUR6_CORAM) FT phosphoribosylaminoimidazole carboxylase catalytic subunit FT PurE from Corynebacterium ammoniagenes (177 aa) fasta FT scores; opt: 666, Z-score: 735.8, 65.541% identity (65.541% FT ungapped) in 148 aa overlap and TR:O80937 (EMBL:AC004684) FT putative phosphoribosylaminoimidazole carboxylase from FT Arabidopsis thaliana (645 aa) fasta scores; opt: 644, FT Z-score: 703.2, 60.870% identity (60.870% ungapped) in 161 FT aa overlap. Contains Pfam match to entry PF00731 AIRC, AIR FT carboxylase." FT /db_xref="GOA:Q93J44" FT /db_xref="HSSP:1O4V" FT /db_xref="InterPro:IPR000031" FT /db_xref="UniProtKB/TrEMBL:Q93J44" FT /protein_id="CAC44524.1" FT /translation="MSQASPVTPVVGIVMGSDSDWPVMEAAAKALDEFEVPYEVDVVSA FT HRMPHEMIAYGEQAAGRGLKAIIAGAGGAAHLPGMLASVTPLPVIGVPVPLKYLDGMDS FT LLSIVQMPAGVPVATVSVGGARNAGLLAARILAAHDEELLGRMREFQQDLNDQATEKGK FT RLRTKVEGSAAGFGFGK" FT misc_feature complement(4073..4543) FT /note="Pfam match to entry PF00731 AIRC, AIR carboxylase, FT score 309.80, E-value 3.1e-89" FT CDS complement(4564..5799) FT /transl_table=11 FT /gene="SCO3060" FT /gene_synonym="purK" FT /gene_synonym="SCBAC19G2.15c" FT /gene_synonym="SCE25.01c" FT /product="phosphoribosylaminoimidazole carboxylase ATPase FT subunit PurK" FT /EC_number="4.1.1.21" FT /note="SCBAC19G2.15, purK, phosphoribosylaminoimidazole FT carboxylase ATPase subunit PurK, len: >110 aa: similar to FT many eg. SW:Q44678 (PURK_CORAM) FT phosphoribosylaminoimidazole carboxylase ATPase subunit FT PurK from Corynebacterium ammoniagenes (413 aa) fasta FT scores; opt: 324, Z-score: 401.4, 47.170% identity FT (48.077% ungapped) in 106 aa overlap." FT /note="SCE25.01c, purK, phosphoribosylaminoimidazole FT carboxylase ATPase subunit PurK, len: >368 aa; highly FT similar to SW:PURK_CORAM (EMBL:X91189) Corynebacterium FT ammoniagenes phosphoribosylaminoimidazole carboxylase FT ATPase subunit (EC 4.1.1.21) PurK, 413 aa; fasta scores: FT opt: 934 z-score: 1056.6 E(): 0; 48.2% identity in 326 aa FT overlap" FT /db_xref="GOA:Q8CJX8" FT /db_xref="HSSP:1B6R" FT /db_xref="InterPro:IPR005875" FT /db_xref="UniProtKB/TrEMBL:Q8CJX8" FT /protein_id="CAD55490.1" FT /translation="MRPATGGGRGRKRPVNRWAPRGRYARGVTFPVVGMVGGGQLARMT FT HEAGIPLGIRFKLLSDTPQDSAAQVVNEVVVGDYRDLDTLREFARGCDVITFDHEHVPT FT EHLKALEADGIPVRPGPEALVHAQDKGVMRAKLDAIGVPCPRHRIVRDPADVAAFAAEG FT AVEGGDGFPVVLKTVRGGYDGKGVWVVDSVAEAAEPFRAGVPVLAEEKVDFVRELAANV FT VRSPHGQAVAYPVVESQQVKGVCDTVIAPAPDLDEALALRAEEMALGIAKELGVVGHLA FT VELFQTRDGRVLVNELAMRPHNSGHWTMDGAITSQFANHVRAVLDLPLGDPRPRAKWTV FT MVNVLGGDYPDMYSAYLHCMARDPQLKIHMYGKDVKPGRKVGHVNTYGDDLDDVLERAR FT HAAGYLRGTITE" FT CDS 5884..6456 FT /transl_table=11 FT /gene="SCO3061" FT /gene_synonym="SCE25.02" FT /product="putative integral membrane protein" FT /note="SCE25.02, possible integral membrane protein, len: FT 190 aa; similar to TR:P96882 (EMBL:Z92771) Mycobacterium FT tuberculosis hypothetical 30.1 kD protein MTCY71.17, 272 FT aa; fasta scores: opt: 197 z-score: 245.6 E(): 3.2e-06; FT 32.0% identity in 150 aa overlap. Contains possible FT hydrophobis membrane spanning regions" FT /db_xref="GOA:Q9KZ84" FT /db_xref="InterPro:IPR007267" FT /db_xref="UniProtKB/TrEMBL:Q9KZ84" FT /protein_id="CAB89433.1" FT /translation="MEHGSSGAQTAPATPPAPRAGMRERVDRLVREVVKFGAVGGAGVL FT VNLLVFNFVRHTTDLQVVRASIVATVVAIVFNYLGFRYFAYRDRDKSGQTREMSLFLLF FT SAVGLVIENGVLYTATYGFGWDSPLQSNIFKFLGIGIGTLFRFWSYRSWVFRALPAREP FT AARAETFLEHEHPTALPRPDGAPAGHR" FT CDS complement(6481..7755) FT /transl_table=11 FT /gene="SCO3062" FT /gene_synonym="SCE25.03c" FT /product="putative two-component system histidine kinase" FT /note="SCE25.03c, probable two-component system histidine FT kinase, len: 424 aa; similar to TR:O86661 (EMBL:AL031182) FT Streptomyces coelicolor putative two-component sensor FT SC4A2.05, 436 aa; fasta scores: opt: 486 z-score: 535.4 FT E(): 2.3e-22; 31.8% identity in 450 aa overlap. Contains FT Pfam match to entry PF00512 signal, Histidine kinase. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9KZ83" FT /db_xref="InterPro:IPR003660" FT /db_xref="UniProtKB/TrEMBL:Q9KZ83" FT /protein_id="CAB89434.1" FT /translation="MRRRLIQSTLAVVLVVIAVFGVSLVIVETRTISSTAQERVDLEAV FT RLASIVDSRLIGTGSVDEDFLREQIRDARYAVIRIPGEPVVEVGTKPTGDVLQGRATGE FT EGETVLVEEPRSSVTREVGRTLLIIGLVALLAVIAAVLLAIRQANRLASPLTDLAETAE FT RLGSGDPRPRHKRYGVPELDRVADVLDSSAERIARMLTAERRLAADASHQLRTPLTALS FT MRLEEITLTDEPETVKEEATIALSQVERLTDVVDRLLTNSRDPRSGSAVTFELDDVIQQ FT QIAEWRPAYRGEGRAIVSSGKRHLTAVGTPGAVAQVLAALIENSLMHGGGTVALRTRVT FT GNQAVVEVTDEGPGVPGDLGARIFERAISGRNSTGIGLAVARDLAEADGGRLELLQGRP FT PVFGLFLSRTPPSKKSPGDGDQTVR" FT misc_feature complement(6535..7122) FT /note="Pfam match to entry PF00512 signal, Histidine FT kinase, score 74.70, E-value 1.9e-18" FT RBS complement(7757..7762) FT CDS complement(7790..8467) FT /transl_table=11 FT /gene="SCO3063" FT /gene_synonym="SCE25.04c" FT /product="putative two-component system reponse regulator" FT /note="SCE25.04c, probable two-component system reponse FT regulator, len: 225 aa; similar to TR:CAB77324 FT (EMBL:AL160331) Streptomyces coelicolor putative response FT regulator SCD8A.03, 223 aa; fasta scores: opt: 688 z-score: FT 781.9 E(): 0; 48.9% identity in 223 aa overlap. Contains FT Pfam matches to entries PF00072 response_reg, Response FT regulator receiver domain and PF00486 trans_reg_C, FT Transcriptional regulatory protein, C terminal" FT /db_xref="GOA:Q9KZ82" FT /db_xref="HSSP:1B00" FT /db_xref="InterPro:IPR001867" FT /db_xref="UniProtKB/TrEMBL:Q9KZ82" FT /protein_id="CAB89435.1" FT /translation="MTRVLLAEDDASISEPLARALRREGYEVEVREDGPTAVDAGLQGG FT IDLVVLDLGLPGMDGLEVARRLRSEGHAVPILILTARADEVDTVVGLDAGADDYVTKPF FT RLAELLARVRALLRRGAAEPPQPPATHGVRIDVESHRAWMGEEELQLTAKEFDLLRVLV FT RDAGRVVTRDQLMREVWDTTWWSSTKTLDMHISWLRKKLGDDAANPRYIATVRGVGFRF FT EKN" FT misc_feature complement(7811..8029) FT /note="Pfam match to entry PF00486 trans_reg_C, FT Transcriptional regulatory protein, C terminal, score FT 123.90, E-value 8.7e-36" FT misc_feature complement(8129..8464) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 136.00, E-value 6.7e-37" FT CDS 8962..10458 FT /transl_table=11 FT /gene="SCO3064" FT /gene_synonym="SCE25.05" FT /product="putative peptide transporter" FT /note="SCE25.05, probable peptide transporter, len: 498 aa; FT similar to SW:DTPT_LACLA (EMBL:U05215) Lactococcus lactis FT di-/tripeptide transporter DtpT, 463 aa; fasta scores: opt: FT 1105 z-score: 1248.4 E(): 0; 38.2% identity in 468 aa FT overlap. Contains Pfam match to entry PF00854 PTR2, POT FT family and match to Prosite entry PS01023 PTR2 family FT proton/oligopeptide symporters signature 2 and possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9KZ81" FT /db_xref="InterPro:IPR005279" FT /db_xref="UniProtKB/TrEMBL:Q9KZ81" FT /protein_id="CAB89436.1" FT /translation="MASSLTKDSVTPGTPGTEKTFFGHPRGLATLFMTEMWERFSYYGM FT RALLPLYLVAPGGLGLGAGTATAIYSVYLSLVYLLTMPGGWFGDRVWGPRKTVAIAGGV FT IMLGHLTLALPSSGTFYAGLGLVAIGSGLLKANISTMVGQLYDGPDDPRRDGGFTVFYM FT GINLGAFAAPLTIGTIGENVNWHLGFALAAVGMGLGVLQFLIGSRHLAPHSSAVPKPLS FT VEEKTSTLRKAAFWAALAVVFYAIVGFSGHYTLNWILVPLTLLGVIIPVLVLTNIKRDK FT SLDRAEQSKMSAYIWFFVAAAVFWMIYDQGGSTLSLFADSSADNSVFGWSFPVSWYQSV FT NPVIIMALAPVFATVWLALNRRGKEPSTVVKFCGGLVLVGASFFLFLAPLGIAEGGHKA FT AAMWLVAIYFVQTCGELMLSPVGLSVTTKMAPVKYASQMMGVWFLAVTAGDATTGLLSI FT AGVDLNKTGIVAAEATLAVVAGVAIWMYRKRVKELMGDVR" FT misc_feature 9244..10311 FT /note="Pfam match to entry PF00854 PTR2, POT family, score FT 192.30, E-value 1.8e-56" FT misc_feature 9433..9471 FT /note="PS01023 PTR2 family proton/oligopeptide symporters FT signature 2" FT CDS 10588..11025 FT /transl_table=11 FT /gene="SCO3065" FT /gene_synonym="SCE25.06" FT /product="conserved hypothetical protein SCE25.06" FT /note="SCE25.06, hypothetical protein, len: 145 aa; similar FT to TR:CAB86125 (EMBL:AL163003) Streptomyces coelicolor FT hypothetical 16.0 kD protein, SCC24.31c, 142 aa; fasta FT scores: opt: 338 z-score: 419.4 E(): 6.6e-16; 42.6% FT identity in 141 aa overlap" FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/TrEMBL:Q9KZ80" FT /protein_id="CAB89437.1" FT /translation="MATRWSLTIDCANPASLAAFWALALGYAEKPAPPGFGSWAEWFAH FT HEVPEDEWDDGAYLSDPDGAGPDLSFLKVPEPKAVKNRLHLDVRVGGGRETPWEVRWPR FT VVEAVERLTAAGATVVREEGLRGRPDHVVMADPEGNEFCLV" FT misc_feature 10955..13434 FT /note="previously sequenced fragment EMBL:AJ249581 FT Streptomyces coelicolor A3(2) sig15 gene, ORFB and ORFA" FT CDS complement(11155..11667) FT /transl_table=11 FT /gene="SCO3066" FT /gene_synonym="SCE25.07c" FT /product="putative regulator of Sig15" FT /note="SCE25.07c, putative regulator of Sig15, len: 170 aa; FT identical to previously sequenced TR:CAB55834 FT (EMBL:AJ249581) Streptomyces coelicolor A3(2) putative FT regulator of Sig15, 170 aa" FT /db_xref="GOA:Q7AKM8" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q7AKM8" FT /protein_id="CAB89438.1" FT /translation="MSTTRPYPPGDRGPEPGGASGTASAPASASGEGGGRQARRLSFED FT ASGVVPLARDFTREALYAWGWLPSATADQRAAAEDVLLVVSELVTNACLHAEGPDELSI FT TCEKKVIRLEVSDRGTGQPAPRTPHRAGRPGGHGMFIVQRLCLDWGVVRTPGVAGKRVW FT AELGAPA" FT RBS complement(11676..11681) FT CDS complement(11864..12241) FT /transl_table=11 FT /gene="SCO3067" FT /gene_synonym="SCE25.08c" FT /product="putative anti anti sigma factor" FT /note="SCE25.08c, putative anti anti sigma factor, len: 125 FT aa; identical to previously sequenced TR:CAB55835 FT (EMBL:AJ249581) Streptomyces coelicolor A3(2) putative anti FT anti sigma factor, 125 aa. Contains Pfam match to entry FT PF01740 SpoIIAA, SpoIIAA family" FT /db_xref="GOA:Q7AKM7" FT /db_xref="InterPro:IPR003658" FT /db_xref="UniProtKB/TrEMBL:Q7AKM7" FT /protein_id="CAB89439.1" FT /translation="MDRGTVGSAQSGRLLVEVREEGPSAVVTPAGELDHHTADLLREPL FT EDCLDKGFNRLVVDCSRLEFCDSTGLNVLLGARLKAEAAGGGVHLVAMQPVVARVFEIT FT GAEAVFTLHDTLAAALADASD" FT misc_feature complement(11885..12205) FT /note="Pfam match to entry PF01740 SpoIIAA, SpoIIAA family, FT score 91.40, E-value 1.8e-23" FT RBS complement(12249..12256) FT RBS 12484..12489 FT CDS 12494..13408 FT /transl_table=11 FT /gene="SCO3068" FT /gene_synonym="sig15" FT /gene_synonym="SCE25.09" FT /product="putative RNA polymerase sigma factor" FT /note="SCE25.09, sig15, putative RNA polymerase sigma FT factor, len: 304 aa; identical to previously sequenced FT TR:CAB55836 (EMBL:AJ249581) Streptomyces coelicolor A3(2) FT putative RNA polymerase sigma factor Sig15, 304 aa. FT Contains Pfam match to entry PF00140 sigma70, Sigma-70 FT factor and match to Prosite entry PS00715 Sigma-70 factors FT family signature 1. Contains also possible helix-turn-helix FT motif at residues 269..290 (+6.83 SD)" FT /db_xref="GOA:Q7AKM6" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q7AKM6" FT /protein_id="CAB89440.1" FT /translation="MSPRLDGSRTHQATSTLPPEHLDPIEHHDAVVDHDDALAGLPDIP FT AYDEVAPADARALSKTLFERLESLEEGTHEHAYVRNTLVELNLALVKFAASRFRSRSEP FT MEDIIQVGTIGLIKAIDRFELSRGVEFPTFAMPTIIGEIKRFFRDTSWSVRVPRRLQEL FT RLDLAKAGDELAQRLDRAPTVSELAEHLGLSKDEVVEGMAASNAYTASSLDAQPEEDDA FT EGALADRIGYEDHGLEGIEYVESLKPLIAELPSRDRKILSLRFVAGMTQSEIGEELGIS FT QMHVSRLLSRTLVRLRKGLTVEE" FT misc_feature 12722..13387 FT /note="Pfam match to entry PF00140 sigma70, Sigma-70 FT factor, score 250.90, E-value 1.8e-71" FT misc_feature 12812..12853 FT /note="PS00715 Sigma-70 factors family signature 1" FT stem_loop 13430..13471 FT /note="8735 CCTGAAGGGGGGCGACCCG 8753 - 8758 FT CGGGCGCCCCCCTTCAGG 8776. Score 50: 18/19 (94%) matches, 0 FT gaps" FT CDS complement(13485..13829) FT /transl_table=11 FT /gene="SCO3069" FT /gene_synonym="SCE25.10c" FT /product="putative integral membrane protein" FT /note="SCE25.10c, possible integral membrane protein, len: FT 114 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9KZ79" FT /protein_id="CAB89441.1" FT /translation="MSRGRRGMAKYWWTPFLLNVLLGIPGVVPFWLVWYLMVNWPLAEL FT GWTVREPTENDGMVLWLVIVVPVVAVFTMIWWLVNAPLRRRTSLTPHTFWLLCGLAPLL FT PTAALIANSP" FT CDS complement(13837..15012) FT /transl_table=11 FT /gene="SCO3070" FT /gene_synonym="SCE25.11c" FT /product="putative chlorohydrolase" FT /note="SCE25.11c, probable chlorohydrolase, len: 391 aa; FT similar to SW:HUTI_BACSU (EMBL:D31856) Bacillus subtilis FT imidazolonepropionase (EC 3.5.2.7) FT (imidazolone-5-propionate hydrolase) HutI, 421 aa; fasta FT scores: opt: 659 z-score: 767.1 E(): 0; 36.1% identity in FT 404 aa overlap. Contains Pfam match to entry PF01685 FT ATZ_TRZ, Chlorohydrolase" FT /db_xref="GOA:Q9KZ78" FT /db_xref="InterPro:IPR005920" FT /db_xref="UniProtKB/Swiss-Prot:Q9KZ78" FT /protein_id="CAB89442.1" FT /translation="MSSSTVITNIAALVTNDPSLGDHSPLGLVRDAAVVVEGDRVVWTG FT ESSKAPATDNRVDADGRAVLPGFVDSHSHLLFAGDRTEEFNARMSGRPYSAGGIRTTVA FT ATRAASDAELEAGLTRYLAEALRQGTTTFETKSGYGLTTADESRALRVAARHTDEVTFL FT GAHIVAPELADDPAAYVDLVTGEMLDACAPHARWIDVFCEKGAFDGDQARAILTAGKAR FT GLHPRIHANQLSYGPGVRLAVELDAASADHCTHLTDADVDALANSRTVATLLPGAEFST FT RAQWPDARRLIDAGATVALSTDCNPGSSFTSSVPFCIALAVRDMGMTPDEAVWSATAGG FT AAALRREDVGRLVPGAYADLTLLDAPSHVHLAYRPGVPLVAGVWRRGVRKV" FT misc_feature complement(13852..14640) FT /note="Pfam match to entry PF01685 ATZ_TRZ, FT Chlorohydrolase, score -55.70, E-value 4e-05" FT CDS complement(15069..16418) FT /transl_table=11 FT /gene="SCO3071" FT /gene_synonym="SCE25.12c" FT /product="putative chlorohydrolase" FT /note="SCE25.12c, possible chlorohydrolase, len: 449 aa; FT similar to SW:ATZA_PSESD (EMBL:U55933) Pseudomonas sp. FT atrazine chlorohydrolase (EC 3.8.1.-) AtzA, 473 aa; fasta FT scores: opt: 401 z-score: 468.3 E(): 1.3e-18; 26.9% FT identity in 428 aa overlap. Contains Pfam match to entry FT PF01685 ATZ_TRZ, Chlorohydrolase" FT /db_xref="GOA:Q9KZ77" FT /db_xref="InterPro:IPR010252" FT /db_xref="UniProtKB/TrEMBL:Q9KZ77" FT /protein_id="CAB89443.1" FT /translation="MTSSEQPRTYWLEHAWLGTHVEPGVALDVRDGRITAVNQGVATPP FT PGAGILRGLTLPGLANAHSHAFHRALRGTVQVGSGTFWTWREVMYSVADRLTPDTYHAL FT ARAVYAEMALAGITAVGEFHYVHHAPGGTPYADPNAMGEALIEAAAEAGVRITLLDTCY FT LSSGFGEPPNTHQRRFSDGTADAWAERCSVLKERDHARIGAAIHSVRAVPADQLATVAQ FT WAEERRAPLHVHLSEQTAENDACRQAHGRTPTRLLADHGVLGARTTGVHNTHLTDEDIA FT LLGGSRTGTCMCLTTERDLADGIGPAAALQRAGSPLSLGSDSHAVVDLLEEARAMELNE FT RLRTRARGHWTAAALLRAATADGHAALGWDDTGRIEAGARADLATIALDSVRTAGPLPR FT LGAETAVFAATAADVRHTVVGGRHVVRDGAHTLVPDVPQALARAVEALRA" FT misc_feature complement(15156..16085) FT /note="Pfam match to entry PF01685 ATZ_TRZ, FT Chlorohydrolase, score 165.50, E-value 9e-46" FT CDS complement(16415..17632) FT /transl_table=11 FT /gene="SCO3072" FT /gene_synonym="SCE25.13c" FT /product="putative amino acid hydrolase" FT /note="SCE25.13c, probable amino acid hydrolase, len: 400 FT aa; similar to SW:AMB2_BACST (EMBL:S67784) Bacillus FT stearothermophilus N-carbamyl-L-amino acid amidohydrolase FT (EC 3.5.1.-) AmaB, 409 aa; fasta scores: opt: 733 z-score: FT 804.8 E(): 0; 34.7% identity in 404 aa overlap" FT /db_xref="GOA:Q9KZ76" FT /db_xref="InterPro:IPR002933" FT /db_xref="UniProtKB/TrEMBL:Q9KZ76" FT /protein_id="CAB89444.1" FT /translation="MSFHSMWAELLPVGRSSASGGYRRAAWTGADADCRTWFQEQAEAR FT GLTYETDRNGNQWAWLGDPAAGNAVVTGSHLDSVPDGGAFDGPLGVVSAFAALDELRGR FT GARFTRPLGIVNFGDEEGARFGLACVGSRLTSGALTVEQAHRLTDGDGITLPQAMEAAG FT YDPGTLGPDPERLARIGAFVELHVEQGRALDLSGDRIGIASAIWPHGRWRFDFRGEANH FT AGTTRLADRHDPMLPYAETVLAARREAQLAGAVATFGKIGVEPNGVNAVPSLVRGWLDS FT RAADQASLDTVVTGIEKAAREYAAARGVDLDVVRESFTPVVEFDHALRDELGRILGTGT FT DLKVPVLGTGAGHDAGILSDRIPTAMLFVRNPTGVSHSPAEYAAEDDCVAGVNALADVL FT EGLACT" FT CDS complement(17629..19347) FT /transl_table=11 FT /gene="SCO3073" FT /gene_synonym="hutU" FT /gene_synonym="SCE25.14c" FT /product="urocanate hydratase" FT /note="SCE25.14c, hutU, urocanate hydratase, len: 572 aa; FT highly similar to SW:HUTU_BACSU (EMBL:D31856) Bacillus FT subtilis urocanate hydratase (EC 4.2.1.49) (urocanase) FT (imidazolonepropionate hydrolase) HutU, 552 aa; fasta FT scores: opt: 2440 z-score: 2699.9 E():0; 66.1% identity in FT 548 aa overlap. Contains Pfam match to entry PF01175 FT Urocanase, Urocanase and match to Prosite entry PS01233 FT Urocanase active site" FT /db_xref="GOA:Q9KZ75" FT /db_xref="InterPro:IPR000193" FT /db_xref="UniProtKB/Swiss-Prot:Q9KZ75" FT /protein_id="CAB89445.1" FT /translation="MSGPRPVRAPRGTEPSALGWQQEAALRMLQNNLDPEVAEHPDKLV FT VYGGTGKAARDWRSFDAMVRTLRTLKQDETMLVQSGRPVGVMQTHEWAPRVLIANSNLV FT GDWANWEEFRRLEALGLTMYGQMTAGSWIYIGTQGILQGTYETFAAVAAKKFGGTLAGT FT ITLTAGLGGMGGAQPLAVTMNDGVVICVDCDPRAIDRRIEHHYLDVKADSLDHALQLAT FT EARDRRKPLSIGVLGNAAELVPQLLAMGAPIDIVTDQTSAHDPLAYLPTGIAFEDMADA FT AAKDPAGFTTRARESMARHVEAMVGFQDAGAEVFDYGNSIRGEAQLAGYDRAFAFPGFV FT PAYIRPLFCEGKGPFRWAALSGDPADIAKTDKAILDLFPENESLARWIKMAGERVHFQG FT LPARICWLGYGERDKAGERFNDMVASGELAAPIVIGRDHLDCGSVASPYRETEAMLDGS FT DAIADWPLLNAMVNVASGASWVSLHHGGGVGMGRSIHAGQVTVADGTPLAGEKIRRVLT FT NDPGMGVIRHVDAGYDIAESVAAERDVRVPMREGDEAHEGDAAHGSGAAREGDGV" FT RBS complement(17642..17646) FT misc_feature complement(17698..19347) FT /note="Pfam match to entry PF01175 Urocanase, Urocanase, FT score 1044.60, E-value 0" FT misc_feature complement(18130..18159) FT /note="PS01233 Urocanase active site" FT RBS complement(19354..19359) FT stem_loop 19457..19492 FT /note="14762 CGAGCGCGGGCCCCG 14778 - 14781 CGGGGGCCCGCGCTCG FT 14979. Score 51: 17/17 (100%) matches, 0 gaps" FT CDS complement(19547..20134) FT /transl_table=11 FT /gene="SCO3074" FT /gene_synonym="SCE25.15c" FT /product="putative integral membrane protein" FT /note="SCE25.15c, possible integral membrane protein, len: FT 195 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9KZ74" FT /protein_id="CAB89446.1" FT /translation="MARGGQVGLARVAVVVRAGAAPLWWLGVFAAGIGVLVPGLTGRRI FT GVLAGAALFIVATAVVAWARRRRYTALAGSAARAGKHDVLQDRGVTVRDWRRGHRWWLL FT LAFLAALGSAFALPAAGGLLLAGCGAGLWLKAAWIGRREQAGDALLWVRVDWLADNAGR FT PAGKAVKAYRSTGIAAGDAAPGGARRKTPATV" FT RBS complement(20141..20146) FT CDS complement(20295..21164) FT /transl_table=11 FT /gene="SCO3075" FT /gene_synonym="SCE25.16c" FT /product="putative transcriptional regulator" FT /note="SCE25.16c, possible transcriptional regulator, len: FT 289 aa; similar to SW:HEXR_PSEAE (EMBL:AF029673) FT Pseudomonas aeruginosa hex regulon repressor HexR, 285 aa; FT fasta scores: opt: 197 z-score: 227.5 E(): 3.2e-05; 27.7% FT identity in 220 aa overlap. Contains possible FT helix-turn-helix motif at residues 50..71 (+2.54 SD)" FT /db_xref="GOA:Q9KZ73" FT /db_xref="InterPro:IPR001347" FT /db_xref="UniProtKB/TrEMBL:Q9KZ73" FT /protein_id="CAB89447.1" FT /translation="MNGTGGTSGASGTDSPAARLQTLFEGHRLTPTQRRIAHSMVRRAS FT DVPFLSSVELAELAGVSQPSVTRFAVALGFDGYPALRRHLREVAPAEPVADTGAVNEYQ FT QAVAAEIENLRHLAEVLADPGPVREAGRLLAASRPLPVLGLRAAAAQAHGFSYFAAKVH FT PDVRLLGEGGTMLRDRIDAAVRAGAGTLLCFALPRHPREVVEALAHAKEAGLTVVTVAD FT SAFAPVAKVSDLLLPAAVGTGLAFDTACAPMLLGRVLLEAMCDDLPDAQARLEEFDTKA FT AARGLFVD" FT RBS complement(21175..21178) FT CDS 21283..21753 FT /transl_table=11 FT /gene="SCO3076" FT /gene_synonym="SCE25.17" FT /product="putative integral membrane protein" FT /note="SCE25.17, possible integral membrane protein, len: FT 156 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9KZ72" FT /protein_id="CAB89448.1" FT /translation="MPTAPRLPTVGSMTGMDARDADLKKELDATLRTRRELGEEYESAL FT VDSFLEKVDQRIDGAVERRVRRQLAEQQMTAARDSRSPRPTDSFGERFGFGIVSLVLAI FT PLSAIGGGVANLPGMLVAWAGIVGVNVVQVARTNPGLFGHRRRAERGDAWED" FT CDS complement(22159..23544) FT /transl_table=11 FT /gene="SCO3077" FT /gene_synonym="SCE25.18c" FT /product="putative cystathionine beta-synthase" FT /note="SCE25.18, probable cystathionine beta-synthase, len: FT 461 aa; highly similar to TR:O53425 (EMBL:AL021897) FT Mycobacterium tuberculosis cystathionine beta-synthase FT CysM, 464 aa; fasta scores: opt: 2025 z-score: 2184.8 E(): FT 0; 67.6% identity in 454 aa overlap, to TR:Q9YHU3 FT (EMBL:AF090120) Fugu rubripe cystathionine beta-synthase, FT 585 aa; fasta scores: opt: 1087 z-score: 1173.5 E(): 0; FT 39.6% identity in 465 aa overlap and to TR:CAB50991 FT (EMBL:AL096852) Streptomyces coelicolor putative cysteine FT synthase SCE19A.10c, 316 aa; fasta scores: opt: 558 FT z-score: 540.6 E(): 1.4e-24; 40.3% identity in 303 aa FT overlap. Contains Pfam matches to entries PF00291 FT S_T_dehydratase, Pyridoxal-phosphate dependent enzyme, 2x FT PF00571 CBS, CBS domain and match to Prosite entry PS00901 FT Cysteine synthase/cystathionine beta-synthase P-phosphate FT attachment site" FT /db_xref="GOA:Q9KZ71" FT /db_xref="HSSP:1M54" FT /db_xref="InterPro:IPR001926" FT /db_xref="UniProtKB/TrEMBL:Q9KZ71" FT /protein_id="CAB89449.1" FT /translation="MQFHDSMISLVGNTPLVRLNSVSKGIRATVLAKVEYFNPGGSVKD FT RIALRMIEAAEKSGELQPGGTIVEPTSGNTGVGLAIVAQQKGYKCIFVCPDKVSTDKIN FT VLRAYGAEVVVCPTAVDPEHPDSYYNVSDRLVRETPGAWKPDQYSNPNNPLSHYHSTGP FT ELWEQTEGKITHFVAGVGTGGTISGTGRYLKDASDGAVTVIGADPEGSVYSGGSGRPYL FT VEGVGEDFWPTAYDREVADEIVAVSDKDSFQMTRRLAKEEGLLVGGSCGMAVVAALEVA FT ARLGEDDVVVVLLPDSGRGYLSKIFNDEWMADYGFLEDTGPSARVAEVLNHKEGGHIPS FT LVHMHPDETVGQAIEVLREYGVSQMPIVKPGAGHPDVMAAEVVGSVVERELLDALFAKR FT ASLEDPLEKHMSAPLPQVGSGEPVADLMSVLGGADAAIVLVEGKPTGVVSRQDLLSFLA FT KVK" FT misc_feature complement(22171..22323) FT /note="Pfam match to entry PF00571 CBS, CBS domain, score FT 13.90, E-value 0.93" FT misc_feature complement(22357..22542) FT /note="Pfam match to entry PF00571 CBS, CBS domain, score FT 31.40, E-value 2.1e-05" FT misc_feature complement(22654..23526) FT /note="Pfam match to entry PF00291 S_T_dehydratase, FT Pyridoxal-phosphate dependent enzyme, score 388.70, E-value FT 5.9e-113" FT misc_feature complement(23392..23448) FT /note="PS00901 Cysteine synthase/cystathionine FT beta-synthase P-phosphate attachment site" FT RBS complement(23550..23554) FT CDS 23712..24734 FT /transl_table=11 FT /gene="SCO3078" FT /gene_synonym="SCE25.19" FT /product="putative secreted protein" FT /note="SCE25.19, possible secreted protein, len: 340 aa; FT similar to TR:O53423 (EMBL:AL021897) Mycobacterium FT tuberculosis hypothetical 32.9 kD protein MTV017.28c, 314 FT aa; fasta scotes: opt: 519 z-score: 544.7 E(): 7e-23; 38.3% FT identity in 332 aa overlap. Contains possible N-terminal FT region signal peptide sequence" FT /db_xref="GOA:Q9KZ70" FT /db_xref="InterPro:IPR001087" FT /db_xref="UniProtKB/TrEMBL:Q9KZ70" FT /protein_id="CAB89450.1" FT /translation="MTSMSRARVARRIAAGAAYGGGGIGLAGAAAVGLVVAEVQLARRR FT VGVGTPTRVPNAQGLYGGTLPTAGDPPLRLMMLGDSTAAGQGVHRAGQTPGALLASGLA FT AVAERPVRLGSVAQPGACSDDLDRQVALVLAEPDRVPDICVIMVGANDVTHRMPATRSV FT RHLSSAVRRLRTAGAEVVVGTCPDLGTIERVRQPLRWLARRASRQLAAAQTIGAVEQGG FT RTVSLGDLLGPEFAQNPRELFGPDNYHPSAEGYATAAMAVLPSVCAALGLWPADEEHPD FT ALRREGFLPVARAAAEAASEAGTEVAAAMPTGPRGPWALLKRRRRRRVSEAEPSSPSGV FT " FT RBS 24951..24954 FT misc_feature 24960..26174 FT /note="Pfam match to entry PF00108 thiolase, Thiolase, FT score 530.20, E-value 1.5e-155" FT CDS 24960..26180 FT /transl_table=11 FT /gene="SCO3079" FT /gene_synonym="SCE25.20" FT /product="putative thiolase" FT /note="SCE25.20, probable thiolase, len: 406 aa; similar to FT SW:CATF_ACICA (EMBL:AF009224) Acinetobacter calcoaceticus FT beta-ketoadipyl CoA thiolase (EC 2.3.1.-) CatF, 401 aa; FT fasta scores: opt: 957 z-score: 1066.1 E(): 0; 40.0% FT identity in 415 aa overlap and to TR:CAB45575 FT (EMBL:AL079355) Streptomyces coelicolor PcaF, FT beta-ketoadipyl CoA thiolase SC4C6.11c, 400 aa; fasta FT scores: opt: 895 z-score: 916.7 E(): 0; 38.9% identity in FT 409 aa overlap. Contains Pfam match to entry PF00108 FT thiolase, Thiolase and match to Prosite entry PS00737 FT Thiolases signature 2" FT /db_xref="GOA:Q9KZ69" FT /db_xref="HSSP:1PXT" FT /db_xref="InterPro:IPR002155" FT /db_xref="UniProtKB/TrEMBL:Q9KZ69" FT /protein_id="CAB89451.1" FT /translation="MPEAVIVSAARSPIGRAFKGSLKDLRADDLAATIIQAALAKVPEL FT DPRDIDDLMLGCGLPGGEQGNNLGRIVAVEMGMDHLPGCTVTRYCSSSLQTSRMALHAI FT KAGEGDVFISAGVEMVSRFAKGNSDSLPDTRNPLFAEAEARTAEVAQQEGTTWHDPRED FT GLVPDPYIAMGQTAENLARAKGITRQDMDEFGVRSQNLAEEAIKNGFWEREITPVTLPD FT GTVVSKDDGPRAGVTLEGVQGLKPVFRPDGLVTAGNCCPLNDGAAALVIMSDTKARELG FT LTPLARIVSTGVSGLSPEIMGLGPVEASKQALSRAGLGVGDIDLVEINEAFAAQVIPSY FT RDLGIPLEKLNVNGGAIAVGHPFGMTGARITGTLINSLRTHDKQFGLETMCVGGGQGMA FT MVIERLS" FT misc_feature 26010..26060 FT /note="PS00737 Thiolases signature 2" FT RBS 26464..26467 FT CDS 26475..27284 FT /transl_table=11 FT /gene="SCO3080" FT /gene_synonym="SCE25.21" FT /product="putative secreted protein" FT /note="SCE25.21, possible secreted protein, len: 269 aa. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="UniProtKB/TrEMBL:Q9KZ68" FT /protein_id="CAB89452.1" FT /translation="MSAMPIALLLTTAATGAVGVAVLRSILVLRRQVTALRAELAESRA FT TATRGRVPAARTTADAEEIRAAVAEALAEERERELAEARAFWAAQETRDASDAPLLLGL FT SDSELFLPRQADLVGLEPVTEPAADADEPAAQDAGHTGPRESAELAAARRRHPSHPDFV FT PNPSPAVNDHDRTVATLEGLAESSVALADVRPGPLGTLDVYVFADGTTLCMTPGHRETA FT ERLAAALGAGQTPYLLGGSGISGAYTLTFACGEENVYILADRVIASL" FT CDS complement(27335..27628) FT /transl_table=11 FT /gene="SCO3081" FT /gene_synonym="SCE25.22c" FT /product="hypothetical protein SCE25.22c" FT /note="SCE25.22c, unknown, len: 97 aa" FT /db_xref="UniProtKB/TrEMBL:Q9KZ67" FT /protein_id="CAB89453.1" FT /translation="MTRAVDDFADRLRAAPQSRLQRGAAAEALGLARELARRAQLVEEP FT GAEPREMPDAGMFAAADQIAVAAHDLALVLEDEGQVEEAAALVEEARKRAGV" FT RBS 27740..27744 FT CDS 27750..27980 FT /transl_table=11 FT /gene="SCO3082" FT /gene_synonym="SCE25.23" FT /product="hypothetical protein SCE25.23" FT /note="SCE25.23, unknown, len: 76 aa" FT /db_xref="UniProtKB/TrEMBL:Q9KZ66" FT /protein_id="CAB89454.1" FT /translation="MSQVFSEETHRNLLARIPQCTGREISDWLRAVEDGPALFRFEEKV FT SWLRHEHNLSYGHAKAIVHEYDLRRAARKLR" FT CDS complement(28052..28975) FT /transl_table=11 FT /gene="SCO3083" FT /gene_synonym="SCE25.24c" FT /product="putative integral membrane protein" FT /note="SCE25.24c, possible integral membrane protein, len: FT 307 aa; highly similar to TR:Q54192 (EMBL:M80628) FT Streptomyces griseus transfer hypothetical product, 293 aa; FT fasta scores: opt: 1265 z-score: 1184.1 E(): 0; 70.7% FT identity in 307 aa overlap. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="InterPro:IPR010539" FT /db_xref="UniProtKB/TrEMBL:Q9KZ65" FT /protein_id="CAB89455.1" FT /translation="MRSRNPVFSRRGFSRDNGYAGFNAAPQAGGPAVATQANPYAQGAQ FT GNPYAQPPAGNPYAQNPYAQPDQQFGAPPQAPATTGRMTMDDVVIRTASTLGVLVVTAA FT LAWALLPVDDANISRSYGIGIGAALIGMVLALVQSFKRKPTPALILSYAAFEGVFLGVV FT SSVVDNRIADGAAMQAVIGTMAVFAGVLIAYKAGWIRVNRRFYGFVMAAALGFVFLMMV FT NLLFAVFGGGDGLGFRSGALGVVFGIVGIILGACFLALDFKQVEDGLAYGAPREEAWFA FT AFGLTLTLVWIYLEFLRLIAILNSND" FT RBS complement(28980..28986) FT CDS complement(29144..30313) FT /transl_table=11 FT /gene="SCO3084" FT /gene_synonym="pobA" FT /gene_synonym="SCE25.25c" FT /product="p-hydroxybenzoate hydroxylase" FT /note="SCE25.25c, pobA, p-hydroxybenzoate hydroxylase, len: FT 389 aa; highly similar to SW:PHHY_PSEAE (EMBL:M23173) FT Pseudomonas aeruginosa p-hydroxybenzoate hydroxylase (EC FT 1.14.13.2) (4-hydroxybenzoate 3-monooxygenase) (PhbH) PobA, FT 394 aa; fasta scores: opt: 1334 z-score: 1559.4 E(): 0; FT 50.9% identity in 389 aa overlap and to TR:Q06519 FT (EMBL:L13747) Pseudomonas fluorescens p-hydroxybenzoate FT hydroxylase (EC 1.14.13.2) (4-hydroxybenzoate FT 3-monooxygenase), 397 aa; fasta scores: opt: 1395 z-score: FT 1630.5 E(): 0; 54.5% identity in 389 aa overlap. Contains FT Pfam matches to entries PF01494 FAD_binding_3, FAD binding FT domainand PF01360 Monooxygenase, Monooxygenase" FT /db_xref="GOA:Q9KZ64" FT /db_xref="HSSP:1PBE" FT /db_xref="InterPro:IPR003042" FT /db_xref="UniProtKB/TrEMBL:Q9KZ64" FT /protein_id="CAB89456.1" FT /translation="MRTTVGIIGAGPAGLLLARLLHNAGIDSVVLESRDRTYVERRQRA FT GILEQGTVDVLRGAGAGERMDREGLRHDGIELRFDRRRHRVDFPALTGGRSVMVYAQTE FT VCKDLIALQIEEGGPLLFETEALAVEGADTDRPRVRFRREGAEDVLECDYVVGCDGFWG FT VARSAVPDGRTFERTYPFSWLGILADVAPSHDELVYARHDRGFALLSMRSPSVSRLYLQ FT VPADTDADSWSDEEIWDELERRFETDDDWSLRRGPITQKSVTPMRSYVHEPMRHGRLFL FT AGDAAHIVPPTGAKGLNLAVGDVVTFARALAHRTATGSDDLLDAYSATCLRRVWQAERF FT SYDMTTLLHTAPDATPFEGRLQLARLDRITSSRAAETDLAEAYTGFPIG" FT misc_feature complement(29297..29863) FT /note="Pfam match to entry PF01360 Monooxygenase, FT Monooxygenase, score 119.90, E-value 4.7e-32" FT misc_feature complement(29891..30301) FT /note="Pfam match to entry PF01494 FAD_binding_3, FAD FT binding domain, score 100.00, E-value 4.5e-26" FT CDS complement(30535..30888) FT /transl_table=11 FT /gene="SCO3085" FT /gene_synonym="SCE25.26c" FT /product="putative membrane protein" FT /note="SCE25.26c, possible membarne protein, len: 117 aa. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9KZ63" FT /db_xref="InterPro:IPR001905" FT /db_xref="UniProtKB/TrEMBL:Q9KZ63" FT /protein_id="CAB89457.1" FT /translation="MSRAGPRPPHGRGRPCDVRRGRLLRGWRLALLWKQIVTILAVGAF FT SFVLTWIIAKAVDVVVGFTDKEAYADVPGQEEERAYDFRTAERLDALAGAGRGTDRETL FT DEIRRLLREHREG" FT RBS 31212..31216 FT CDS 31223..32002 FT /transl_table=11 FT /gene="SCO3086" FT /gene_synonym="SCE25.27" FT /product="putative lipoprotein" FT /note="SCE25.27, possible lipoprotein, len: 259 aa. FT Contains matches to Prosite entries PS00013 Prokaryotic FT membrane lipoprotein lipid attachment site (correctly FT situated) and PS00017 ATP/GTP-binding site motif A FT (P-loop), possible N-terminal region signal peptide FT sequence and high content in alanine and glycine amino acid FT residues" FT /db_xref="UniProtKB/TrEMBL:Q9KZ62" FT /protein_id="CAB89458.1" FT /translation="MLRTHRRKSVLAAAALVATTMLLTACQGEDTEDGGKSTGATASDS FT AAKGKSDDGGSGTGTGGKSPSGSKGSKSGMVSGKWAGTVAYLAPGKYTITDANGAEQAF FT FTAEDTDIEGAGKICGDADGQAATPCTEEELEAAAKQGFGATVDVKDGVAVSIIEDHTD FT SGNGNGMGEGERSGLFSGTLGYMAPGKYSLSRDGNERAFFTATDTVINGAGWICGDAQT FT VTPCTEEDLEAAARKGSVAVAVQVEDGVAVTIDEEHN" FT misc_feature 31268..31300 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature 31391..31414 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT repeat_region 31599..31640 FT /note="degenerate 2x repeat: P(P/S)R(R/P)APRK(S/T)SRPRP" FT repeat_region 31887..31928 FT /note="degenerate 2x repeat: P(P/S)R(R/P)APRK(S/T)SRPRP" FT CDS complement(32029..32674) FT /pseudo FT /transl_table=11 FT /gene="SCO3087" FT /gene_synonym="SCE25.28c" FT /note="SCE25.29c, possible pseudogene, 646 bp; similar to FT SW:YHIM_ECOLI (EMBL:U00039) Escherichia coli hypothetical FT 39.2 kD protein in RhsB-Pit intergenic region YhiM, 364 aa; FT fasta scores: opt: 284 z-score: 377.0 E(): 1.5e-1; 61.6% FT identity in 73 aa overlap" FT misc_feature complement(32450..33322) FT /note="previously sequenced fragment EMBL:Y00209 FT Streptomyces coelicolor bldA gene for tRNA-like product" FT tRNA complement(32690..32776) FT /gene="bldA" FT /note="tRNA Leu anticodon TAA (bldA), Cove score 58.78" FT CDS complement(32894..33139) FT /transl_table=11 FT /gene="SCO3088" FT /gene_synonym="SCE25.29c" FT /product="hypothetical protein SCE29c" FT /note="SCE25.29c, doubtful CDS, function unknown, len: 81 FT aa. Hig content in alanine and glycine amino acid residues" FT /db_xref="UniProtKB/TrEMBL:Q9KZ61" FT /protein_id="CAB89460.1" FT /translation="MLGDVVNRPGRTAPCSQPLFRFRGATSVGRAGPVSYLRMTADPDG FT GAGENGAGALVETVKSRHSAYSAGGRTQGCWHVLLA" FT repeat_region 33136..33149 FT /note="degenerate 6x repeat GCAC(G/A)C(G/A)CCGT(G/A)CC" FT repeat_region 33154..33167 FT /note="degenerate 6x repeat GCAC(G/A)C(G/A)CCGT(G/A)CC" FT repeat_region 33170..33183 FT /note="degenerate 6x repeat GCAC(G/A)C(G/A)CCGT(G/A)CC" FT repeat_region 33186..33199 FT /note="degenerate 6x repeat GCAC(G/A)C(G/A)CCGT(G/A)CC" FT repeat_region 33203..33216 FT /note="degenerate 6x repeat GCAC(G/A)C(G/A)CCGT(G/A)CC" FT repeat_region 33221..33234 FT /note="degenerate 6x repeat GCAC(G/A)C(G/A)CCGT(G/A)CC" FT RBS 33238..33242 FT CDS 33253..34023 FT /transl_table=11 FT /gene="SCO3089" FT /gene_synonym="SCE25.30" FT /product="putative ABC transporter ATP-binding protein" FT /note="SCE25.30 probable ABC transporter ATP-binding FT protein, len: 256 aa; similar to TR:CAB81857 (EMBL:AL16169) FT Streptomyces coelicolor putative ABC transporter FT ATP-binding protein SCD40A.12c, 246 aa; fasta scores: opt: FT 922 z-score: 1039.0 E(): 0; 58.4% identity in 238 aa FT overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC FT transporter and matches to Prosite entries PS00017 FT ATP/GTP-binding site motif A (P-loop) and PS00211 ABC FT transporters family signature" FT /db_xref="GOA:Q9KZ60" FT /db_xref="HSSP:1L2T" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9KZ60" FT /protein_id="CAB89461.1" FT /translation="MTTAPIADRSTLVAARATELSKIYGQGETQVVALDRVSIDFRQAE FT LTAIMGPSGSGKSTLMHCVAGLDTFSSGSVRIGETELGSLKDKQLTKLRRDKIGFIFQA FT FNLLPTLTALENITLPMDIAGRKPDKQWVDSVIEMVGLSGRLGHRPAQLSGGQQQRVAV FT ARALASRPEIIFGDEPTGNLDSRSGAEVLGFLRNSVRELGQTVVMVTHDPVAAAYADRV FT VFLADGRIVDELYGPTADSVLDRMKRFDAKGRTS" FT misc_feature 33382..33936 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 191.40, E-value 1.4e-53" FT misc_feature 33403..33426 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 33709..33753 FT /note="PS00211 ABC transporters family signature" FT CDS 34130..36661 FT /transl_table=11 FT /gene="SCO3090" FT /gene_synonym="SCE25.31" FT /product="putative ABC transporter integral membrane FT protein" FT /note="SCE25.31, possible ABC transporter integral membrane FT protein, len: 843 aa; similar to TR:CAB77000 FT (EMBL:AL159178) Streptomyces coelicolor putative integral FT membrane protein SCH22A.31, 850 aa; fasta scores: opt: 675 FT z-score: 676.0 E(): 3.4e-30; 26.4% identity in 879 aa FT overlap. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="GOA:Q9KZ59" FT /db_xref="InterPro:IPR003838" FT /db_xref="UniProtKB/TrEMBL:Q9KZ59" FT /protein_id="CAB89462.1" FT /translation="MFRTALRNVFAHKARLLMTVLAVMLGVAFVSGTLVFADTLSNAFR FT NQSAKSYQDVAVAVTSYADSDNPKDEYALSDEVLDRISAVDGVAGVYGRVEGFAGVADP FT DGKLIGVGWSNKGSNFAPGKDGKDAAYTFTDGSGPVKDDQIALDEDSAGKGEYQVGDRV FT RVATNGPVKEYTLSGVFTTEDGAVNAGGSLVLFDTAVAQKQYLRPGYFESATVAAAPGA FT DDARILKAVEPLLPDTAEAQTGRALADEQADQIEQGMGNLKQVLLGFAGIALFVGIFLI FT SNTFTMLVAQRTKEIALMRAVGASRRQITRSVLAEAALVGLVASAVGFALGVGLAVGLR FT SGMAAFDMKMPAGPLVLSATPVVAAFAVGVLITVFAAWLPGRRAAKIPPVAAMNSVHAV FT ATTKSLVVRNSIGAAITALGAAGIVAGASAGGDDGRMYIGAGAFFALIGVIVLIPLLSR FT PVIALVRPLLVGPFGVAGKLAGQNAVRNPRRTGATASALAIGLTLVTALSVLGVTVGAA FT IDKMTTDNIRADYMVSMANGGDLDRSALTALEKADGVSAVSPQQDAYFQVDGEYVSASA FT ITPGDIEKVLTVDVVSGNAGSLAQGRIAVAEKTAENRGWKPGDTVPVTFDDDEKATLTV FT GAVYKDSEFLSPVLVDRKVVDRHEAKPSIRQIFVKVDGGQSAANEKVLVDALGDNPAIT FT VMDRQDIRDEFGGAINTLLNVMYGLLAMALIIAVLGVVNTLAMSVFERQQEIGMLRAIG FT LDRRRVKRMVRLEAVVISVFGAVVGIGLGTFLGWAIGETVADSIPGYALVLPWDRIGIF FT VVLAGLVGVLAALWPARNAARLNMLNAIKAE" FT CDS complement(36733..38049) FT /transl_table=11 FT /gene="SCO3091" FT /gene_synonym="SCE25.32c" FT /product="cyclopropane-fatty-acyl-phospholipid synthase" FT /note="SCE25.32c, cyclopropane-fatty-acyl-phospholipid FT synthase, len: 438 aa; similar to TR:AAF1173 FT (EMBL:AE002051) Deinococcus radiodurans FT cyclopropane-fatty-acyl-phospholipid synthase, putative FT DR2187, 462 aa; fasta scores: opt: 832 z-score: 910.3 E(): FT 0; 42.7% identity in 433 aa overlap and to SW:CFA_ECOLI FT (EMBL:M98330) Escherichia coli FT cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) FT (cyclopropane fatty acid synthase) (CFA synthase) Cfa or FT CdfA, 381 aa; fasta scores: opt: 482 z-score: 530.2 E(): FT 4.5e-22; 38.0% identity in 303 aa overlap" FT /db_xref="GOA:Q9KZ58" FT /db_xref="HSSP:1KPH" FT /db_xref="InterPro:IPR003333" FT /db_xref="UniProtKB/TrEMBL:Q9KZ58" FT /protein_id="CAB89463.1" FT /translation="MADAALRLQNLFEQLLGAPLPVRIRAWDGSQAGPPGAPTLVVRNR FT RALRRLLFKPGELGLARAWVAGDIDIDGDLYTALGLMAGLIWERGEDARGLVEALRDPE FT VRAAVRGLVKLAGPPLPPAPPPEEVRRARGHLHTKRSDKRAISHHYDVGNDFYELVLGP FT SMVYSCAYWPAPPAEGGTLEDAQRDKLELVSRKLDLSPGRRLLDVGCGWGSMAIHAARE FT HGVSVVGVTLSQEQAAYARKRVADEGLTDRVEIRVQDYRDVADGPYDAISSIGMAEHVG FT AERYLEYATDLHRLLKPGGRLLNHQIARRPQRDESSYNVDEFIDAYVFPDGELAPVGTT FT VTQLERAGFEVRDVESIREHYALTLRRWVANLESDWATAVRLVSPGRARVWQLYMAASA FT LAFERNRIGVNQVLAVKTPDSGASGLPLRARVWGAPGRA" FT RBS complement(38056..38060) FT CDS complement(38313..39653) FT /transl_table=11 FT /gene="SCO3092" FT /gene_synonym="SCE41.01c" FT /gene_synonym="SCE25.33c" FT /product="putative oxidoreductase" FT /note="SCE41.01c, probable oxidoreductase (fragment), len: FT >317 aa; similar to SW:DHNA_ECOLI (EMBL:V00306) Escherichia FT coli NADH dehydrogenase (EC 1.6.99.3) Ndh, 433 aa; fasta FT scores: opt: 361 z-score: 417.8 E(): 9.1e-16; 27.6% FT identity in 330 aa overlap and to TR:CAB92372 FT (EMBL:AL356612) Streptomyces coelicolor putative NADH FT dehydrogenase SCD72A.05, 442 aa; fasta scores: opt: 1185 FT z-score: 1267.3 E(): 0; 57.0% identity in 321 aa overlap. FT Contains Pfam match to entry PF00070 pyr_redox, Pyridine FT nucleotide-disulphide oxidoreductase" FT /note="SCE25.33c, possible dehydrogenase (fragment), len: FT >162 aa; similar to TR:Q9ZC17 (EMBL:AL033505) Streptomyces FT coelicolor putative dehydrogenase SC1E6.05, 629 aa; fasta FT scores: opt: 209 z-score: 253.8 E(): 1.1e-06; 32.6% FT identity in 141 aa overlap and to C-terminal region of FT SW:DHNA_ECOLI (EMBL:V00306) Escherichia coli NADH FT dehydrogenase (EC 1.6.99.3) Ndh, 433 aa; fasta scores: opt: FT 116 z-score: 145.6 E(): 1.2; 26.8% identity in 82 aa FT overlap" FT /db_xref="GOA:Q8CJX7" FT /db_xref="InterPro:IPR013027" FT /db_xref="UniProtKB/TrEMBL:Q8CJX7" FT /protein_id="CAD55492.1" FT /translation="MRYGEATVTVVDPRSYMTYQPFLPEAAAGSISPRHVVVPLRRVLP FT KAEVLTGRVTTIDQDRKVATVAPLVGEAYELPFDYLVIAMGAVSRTFPIPGLAEQGIGM FT KGIEESIGLRNHVLEQLDKADSTTDEEIRRKALTFVFVGGGFAGAETIGEVEDMARDAA FT KYYNNVSREDMRFILVDAADKILPEVGPKLGQYGKEHLEGRGVEVYLSTSMDSCVDGHV FT VLKNGLEVDSNTIVWTAGVKPNPALARFGLPLGPRGHVDTQATLQVQGTDYIWAAGDNA FT QVPDLVGRKAGNENAWCPPNAQHALRQAKVLGDNVISGMRGFPQKPYSHANKGAVAGLG FT LHKGVAMIVMGKMKIKLKGRLAWYMHRGYHGMAMPTFNRKIRVFADWTLGMFLKREVVS FT LGAMETPREEFYEAAKPAPKPAAAKAADQGDQSEKAAKQEKTEAKAS" FT misc_feature complement(38814..39500) FT /note="Pfam match to entry PF00070 pyr_redox, Pyridine FT nucleotide-disulphide oxidoreductase, score 76.80, E-value FT 6.7e-22" FT CDS complement(40179..41120) FT /transl_table=11 FT /gene="SCO3093" FT /gene_synonym="SCE41.02c" FT /product="putative hydrolase" FT /note="SCE41.02c, possible hydrolase, len: 313 aa; similar FT to N-terminal region of SW:GPPA_ECOLI (EMBL:M87049) FT Escherichia coli guanosine-5'-triphosphate,3'-diphosphate FT pyrophosphatase (EC 3.6.1.40) GppA, 494 aa; fasta scores: FT opt: 311 z-score: 357.2 E(): 2.2e-12; 28.4% identity in 310 FT aa overlap" FT /db_xref="GOA:Q9F2Q6" FT /db_xref="InterPro:IPR003695" FT /db_xref="UniProtKB/TrEMBL:Q9F2Q6" FT /protein_id="CAC09534.1" FT /translation="MTRVAAVDCGTNSIRLLVADADPATGELTDLDRRMTIVRLGQGVD FT RTGRLAPEALERTFAACREYAEVVKAHGAERLRFVATSASRDAENRDDFVRGVLDILGV FT EPEVISGDQEAEFSFTGATKELTGRADLDKPYLVVDIGGGSTEFVVGEDHVRAARSVDV FT GCVRMTERHLVRDGAVTDPPTAEQVAAMRADIEAALDLAGRTVPLGEARTLVGLAGSVT FT TVSAIAQELPEYDSAAIHHSRVSRDRVREITDWLLASTHAERAAVASMHPGRVDVIAAG FT SLVLLAIMERTGAEEVVVSEHDILDGIAWSIA" FT CDS complement(41117..41677) FT /transl_table=11 FT /gene="SCO3094" FT /gene_synonym="SCE41.03c" FT /product="conserved hypothetical protein" FT /note="SCE41.03c, conserved hypothetical protein, len: 186 FT aa; similar to TR:P96375 (EMBL:Z92539) Mycobacterium FT tuberculosis hypothetical 16.6 kDa protein MTCY10G2.24c, FT 155 aa; fasta scores: opt: 632 z-score: 730.7 E(): 0; 67.6% FT identity in 136 aa overlap" FT /db_xref="InterPro:IPR007511" FT /db_xref="UniProtKB/TrEMBL:Q9F2Q5" FT /protein_id="CAC09535.1" FT /translation="MQTPPPTTPRTEPTDADVAAFKQQLGRPPRGLRAIAHRCPCGQPD FT VVETAPRLPDGTPFPTLYYLTCPKAASAIGTLEANGVMKEMTERLATDPELAAAYRAAH FT EDYIRRRDEIEELTGFPSAGGMPDRVKCLHVLVAHSLAAGPGVNPLGDEAIAMLPEWWR FT KGPCVTPTEQTDETDETGQEDAQ" FT RBS complement(41127..41136) FT CDS complement(41763..42287) FT /transl_table=11 FT /gene="SCO3095" FT /gene_synonym="SCE41.04c" FT /product="putative membrane protein" FT /note="SCE41.04c, putative membrane protein, len: 174 aa; FT similar to TR:P96376 (EMBL:Z92539) Mycobacterium FT tuberculosis hypothetical 24.6 kDa protein MTC10G2.25c, 228 FT aa; fasta scores: opt: 273 z-score: 332.6 E(): 5.1e-11; FT 35.6% identity in 149 aa overlap. Contains possible FT coiled-coil region at approx residues 87..106 and possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9F2Q4" FT /db_xref="InterPro:IPR007060" FT /db_xref="UniProtKB/TrEMBL:Q9F2Q4" FT /protein_id="CAC09536.1" FT /translation="MCGDVRACTGGGDQMAVKDRDRFSTATRIRIIGEQTAARVYRSQT FT KRQARRSRLTGRAALLAMVLCSLVVALAYPIRQYVAQRAEIADLQREQRETRQRVEDLR FT DLKARWQDDAYAEQQVRLRLHYVMPGETGFVVVDPEAAEQTRARAGAADRPWYQNVWDG FT VDKADAVARRQ" FT CDS complement(42341..43621) FT /transl_table=11 FT /gene="SCO3096" FT /gene_synonym="eno" FT /gene_synonym="SCE41.05c" FT /product="enolase" FT /note="SCE41.05c, eno, enolase, len: 426 aa; similar to FT SW:ENO_ECOLI (EMBL:X82400) Escherichia coli enolase (EC FT 4.2.1.11) Eno, 431 aa; fasta scores: opt: 1603 z-score: FT 1807.6 E(): 0; 60.6% identity in 419 aa overlap. Contains FT Pfam match to entry PF00113 enolase, Enol-ase and match to FT Prosite entry PS00164 Enolase signature" FT /db_xref="GOA:Q9F2Q3" FT /db_xref="HSSP:1OEP" FT /db_xref="InterPro:IPR000941" FT /db_xref="UniProtKB/Swiss-Prot:Q9F2Q3" FT /protein_id="CAC09537.1" FT /translation="MPSIDVVVAREILDSRGNPTVEVEVGLDDGSTGRAAVPSGASTGA FT FEAIELRDGDPSRYLGKGVEKAVLAVIEQIGPELVGYDATEQRLIDQAMFDLDATDNKG FT SLGANAILGVSLAVAHAASEASDLPLFRYLGGPNAHLLPVPMMNILNGGSHADSNVDIQ FT EFMIAPIGAESFSEALRWGAEVYHTLKKVLKNKGLATGLGDEGGFAPNLGSNREALDLI FT LEAIKEAGYTPGEQIALALDVAASEFYKDGSYAFEGKNRSAAEMTEYYAELVEAYPLVS FT IEDPLFEDDWDGWNTITAKLGDKVQLVGDDLFVTNPERLARGIEENSANALLVKVNQIG FT SLTETLDAVELAQRNGFKCMMSHRSGETEDVTIADLAVATNCGQIKTGAPARSERVAKY FT NQLLRIEEILDDAAVYAGRSAFPRFKG" FT misc_feature complement(42350..43618) FT /note="Pfam match to entry PF00113 enolase, Enol-ase, score FT 835.40, E-value 1.9e-247" FT misc_feature complement(42587..42628) FT /note="PS00164 Enolase signature" FT RBS complement(43628..43633) FT CDS complement(43883..44617) FT /transl_table=11 FT /gene="SCO3097" FT /gene_synonym="SCE41.06c" FT /product="putative secreted protein" FT /note="SCE41.06c, possible secreted protein, len: 244 aa; FT similar to TR:O86308 (EMBL:Z96935) Micrococcus luteus Rpf FT protein precursor, 220 aa; fasta scores: opt: 366 z-score: FT 357.9 E(): 2e-12; 39.7% identity in 234 aa overlap. FT Contains Pfam match to entry PF01476 PG_binding_2, Putative FT peptidoglycan binding domain and possible N-terminal region FT signal peptide sequence" FT /db_xref="GOA:Q9F2Q2" FT /db_xref="InterPro:IPR010618" FT /db_xref="UniProtKB/TrEMBL:Q9F2Q2" FT /protein_id="CAC09538.1" FT /translation="MLFSGKGKHRRPSKATRVIAVAGVTGAAVAAPLMAAGNASAATAS FT EWDAVAQCESGGNWSINTGNGYYGGLQFSASTWAAYGGTQYASTADQASKSQQIQIAEK FT VLAGQGKGAWPVCGTGLSGAAYTGGGSEGSGSGSSEGSQSQSSGSTAERSTEQKASRSA FT ERPAAEPKAEKPAAKKKTVTTPTGKKVEKGDGEYKVVKGDTLSSIAEEHDVKGGWAKLF FT KLNDDIVDDADLIYPGQQLHLK" FT misc_feature complement(43886..44029) FT /note="Pfam match to entry PF01476 PG_binding_2, Putative FT peptidoglycan binding domain, score 42.60, E-value 8.6e-09" FT misc_feature complement(44171..44236) FT /note="high glycine and serine amino acid residues content FT region" FT RBS complement(44627..44630) FT CDS complement(44971..45996) FT /transl_table=11 FT /gene="SCO3098" FT /gene_synonym="SCE41.07c" FT /product="putative secreted protein" FT /note="SCE41.07c, possible secreted protein, len: 341 aa; FT similar to TR:O53879 (EMBL:AL022004) Mycobacterium FT tuberculosis hypothetical 40.0 kDa protein MTV043.60c, 407 FT aa; fasta scores: opt: 443 z-score: 346.0 E(): 9.1e-12; FT 33.3% identity in 234 aa overlap. Contains Pfam match to FT entry PF01476 PG_binding_2, Putative peptidoglycan binding FT domain and high content in serine and glycine amino acid FT residues. Also contains a possible N-terminal region signal FT peptide sequence" FT /db_xref="GOA:Q9F2Q1" FT /db_xref="InterPro:IPR010618" FT /db_xref="UniProtKB/TrEMBL:Q9F2Q1" FT /protein_id="CAC09539.1" FT /translation="MLSGNGRHRRPRQAPALVVAAGVTGSAIAIPLLGATGAHAADSTN FT WDQVAECETGGAWSQNSGNGYYGGLQLSQDAWEQYGGLDYAPSADQASRSQQIRIAEKI FT HASQGIAAWPTCGLLAGLGNGSGGTGDGSGAAGDGASEGSDASGEQDTTKSSESPATTE FT TPESSQSSESSGSSETPESTSGASSSSPSPSSSPSSSDAPSDGSSGASGDSSDGAGQSA FT KPDTSTESDPSGSAEPQGTEGSSGSGKHRGGSADEGATGEGRTDPASGRHASRDGGERE FT AGDGRYVVRTGDSLWAIADSLDVDGGWHALYADNETVVGADPDHILPGQTLTVTGESGE FT K" FT misc_feature complement(44992..45138) FT /note="Pfam match to entry PF01476 PG_binding_2, Putative FT peptidoglycan binding domain, score 27.60, E-value 0.00028" FT misc_feature complement(45235..45648) FT /note="high glycine and serine amino acid residues content FT region" FT CDS complement(46140..47441) FT /transl_table=11 FT /gene="SCO3099" FT /gene_synonym="SCE41.08c" FT /product="putative cytochrome P450 hydroxylase" FT /note="SCE41.08c, probable cytochrome P450 hydroxylase, FT len: 433 aa; similar to SW:CPXR_BRAJA (EMBL:U12678) FT Bradyrhizobium japonicum cytochrome P450 BJ-3 (EC FT 1.14.14.-) CYP114, 429 aa; fasta scores: opt: 682 z-score: FT 792.5 E(): 0; 32.9% identity in 435 aa overlap. Contains FT Pfam match to entry PF00067 p450, Cytochrome P450" FT /db_xref="GOA:Q9F2Q0" FT /db_xref="HSSP:1UED" FT /db_xref="InterPro:IPR002397" FT /db_xref="UniProtKB/TrEMBL:Q9F2Q0" FT /protein_id="CAC09540.1" FT /translation="MTGSSSAPVPELFSWEFASDPYPAYAWLREHAPVHRTRLPSGVEA FT WLVTRYADAKQALADPRLSKNPAHHDEPAHAKGKTGIPGERKAELMTHLLNIDPPDHTR FT LRRLVSKAFTPRRVAEFAPRVQELADGLIDRFADTGSADLIHDFAFPLPIYAICDLLGV FT PREDQDDFRDWAGMMIRHQGGPRGGVARSVKKMRGYLADLIHRKRAALPPEPAPGEDLI FT SGLIRASDHGEHLTENEAAAMAFILLFAGFETTVNLVGNGTYALLTHPEQRERLQTSLA FT AGERGLLETGVEELLRYDGPVELATWRFATRPLTIGGQDVAAGDPVLVVLAAADRDPER FT FTDPDTLDLARRDSQHLGYGHGIHYCLGAPLARLEGQTALATLLTRLPDLRLAADPAEL FT RWRGGLIMRGLRTLPVSFTPPASSAGNGPSPTQK" FT misc_feature complement(46179..47357) FT /note="Pfam match to entry PF00067 p450, Cytochrome P450" FT CDS complement(47438..48415) FT /transl_table=11 FT /gene="SCO3100" FT /gene_synonym="SCE41.09c" FT /product="conserved hypothetical protein" FT /note="SCE41.09c, conserved hypothetical protein, len: 325 FT aa; similar to SW:YBL1_STRCI (EMBL:D00937) Streptomyces FT cacaoi hypothetical 26.1 kDa protein in BlaB 3' region, 242 FT aa; fasta scores: opt: 1157 z-score: 1300.4 E(): 0; 72.7% FT identity in 242 aa overlap" FT /db_xref="InterPro:IPR004518" FT /db_xref="UniProtKB/TrEMBL:Q9F2P9" FT /protein_id="CAC09541.1" FT /translation="MNATTAGATAPDQGRIVLLTTSHRVAPGLLSWPAWQALRTADRVV FT CADGAHPQLPYLREAGIRVEETAPTAEELVDDCAGGRTAVVVATGEGDPALTDGLARLA FT GSGRVPMPDLELLPASYDLPGARLLDLVQVMDRIRLECPWSSQRTHEGLAKYAIEEAYE FT LVEAIEDGDRDELREELGDVLLQVVFHARIAEEDPDAPFSVDDVAGTIVDKLVHRHPHV FT FGDETADTPEEVRAHWLRTKAAEKQRTSVTEGVPLGQPGLALAAKLHSRVRTAGLDVPL FT PAGEGIGYDLLALAARAESEGTDPEAALRAAARTYRDAIRAVEG" FT RBS complement(47443..47446) FT RBS complement(48417..48420) FT CDS complement(48492..49139) FT /transl_table=11 FT /gene="SCO3101" FT /gene_synonym="SCE41.10c" FT /product="putative lipoprotein" FT /note="SCE41.10c, possible lipoprotein, len: 215 aa. FT Contains correctly situated match to Prosite entry PS00013 FT Prokaryotic membrane lipoprotein lipid attachment site and FT possible N-terminal region signal peptide sequence" FT /db_xref="InterPro:IPR017909" FT /db_xref="UniProtKB/TrEMBL:Q9F2P8" FT /protein_id="CAC09542.1" FT /translation="MHRRRRSALLLTAAIAAAAPLLAACGNDAHPGAAAVVGDQRITVA FT QLENRVDEVREAQRAAVPDDTQYQQVVARTGTLTRDTLHGMVLDRVLHRAAQDAGVTVS FT RKEVQDMRGELEKQAGGPEQLETVWLQQYGVAPDRLDDNLLVQIEAQKLAQSLGTDTSR FT PEFWQALSEASKKLGVDLNPRYGAWDVQKSSRVDTRTPWVREITAAGSQQPA" FT misc_feature complement(49065..49097) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature complement(49086..51005) FT /note="previously sequenced DNA fragment. EMBL:AB018799 FT Streptomyces coelicolor gene for eukaryotic-type protein FT kinase, complete cds." FT RBS complement(49144..49149) FT CDS complement(49290..50753) FT /transl_table=11 FT /gene="SCO3102" FT /gene_synonym="pkaE" FT /gene_synonym="SCE41.11c" FT /product="eukaryotic-type protein kinase" FT /note="SCE41.11c, pkaE, eukaryotic-type protein kinase, FT len: 487 aa; identical to previously sequenced TR:Q9ZNB6 FT (EMBL:AB018799) Streptomyces coelicolor eukaryotic-type FT protein kinase PkaE, 287 aa. Contains Pfam match to entry FT PF00069 pkinase, Eukaryotic protein kinase domain and FT matches to Prosite entries PS00107 Protein kinases FT ATP-binding region signature and PS00108 Serine/Threonine FT protein kinases active-site signature" FT /db_xref="GOA:Q9ZNB6" FT /db_xref="HSSP:1MRU" FT /db_xref="InterPro:IPR017442" FT /db_xref="UniProtKB/TrEMBL:Q9ZNB6" FT /protein_id="CAC09543.1" FT /translation="MGQVWTAYDRRLDRRVAVKLLRPDKVAGAEADELRRRFVRECRIT FT AQVDHPGLVTVHDAGSEGEELFLVMQYVDGADLSDHLAEHDPYPWQWAVAVAAQLCAVL FT SAVHAVPIVHRDLKPRNVMVKQDGTVTVLDLGVASVMDADTTRLTHTGTPIGSPAYMAP FT EQAMGGAVGPYTDLYALGVLLHELLSGDVPFAGSTALGVLHRHLYEPPLPVRRIRPEVP FT EALEALVLRLLAKDPQHRPDSAQEVYEHLALLLPALGVPTGGPLDPTRPFVRPHAPWPD FT RARTPAPQPAPVPPAAEAAKPDVARAVDDVKRLLGEGRITQAVDVLGAILPAAAEQHGE FT RSPVVRTLRRQYAATLMDDGQYRRALPELRRLADERAAEAGQADPQCLRHRYDAAQCLE FT QLGEPAAALAEYRALLPYYENQYVAGDPDLAHDVRRRIGHLLLALGDRAAAHDTLARLL FT HDVERVHGPGHPLAADIRRTLQWLGRMHG" FT misc_feature complement(49995..50753) FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 202.00, E-value 9e-57" FT misc_feature complement(50382..50420) FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT misc_feature complement(50697..50753) FT /note="PS00107 Protein kinases ATP-binding region FT signature" FT CDS complement(50819..51424) FT /transl_table=11 FT /gene="SCO3103" FT /gene_synonym="SCE41.12c" FT /product="putative integral membrane protein" FT /note="SCE41.12c, possible integral membrane protein, len: FT 201 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9F2P7" FT /protein_id="CAC09544.1" FT /translation="MHGHGYAPPPPPRRPRTAVLVLSRVFFVALALLSIGFLAWISTLY FT AAIVSRRPRDWWVFAATAAALVISFCFLATDDTDDFSTPAGTTGMIILLLNACVCAGYF FT LYADISHHRRPPHPGHVVAMPPPLAAGYGHPQPSYPYTPPPAAPVQTPVPPYQAAPPQH FT PPAPARIDQVRAELDELSDYLRNHDGRDGRDGGHRGGR" FT RBS complement(51430..51436) FT CDS complement(51563..53602) FT /transl_table=11 FT /gene="SCO3104" FT /gene_synonym="SCE41.13c" FT /product="hypothetical protein SCE41.13c" FT /note="SCE41.13c, unknown, len: 679 aa" FT /db_xref="GOA:Q9F2P6" FT /db_xref="InterPro:IPR003356" FT /db_xref="UniProtKB/TrEMBL:Q9F2P6" FT /protein_id="CAC09545.1" FT /translation="MQEHGTEVTAAGIARLAGVGRAAVSNWRRRHADFPRPVGGTETSP FT SFALADVEAWLRAQGKLAEVPPRERVWQQLAGHPEGPVAALVQAGCVLLLIHDRPTLWL FT DASAGSDERLADLLPPALDQVLDARFGTGPQRAVTTPAGPRLLPSAPLLRGAAELAAGP FT GARKAYEFLLGRHLDANPRQYTLTPDPLADLMAELAGPARTVLDPACGTGSLLRAAAAT FT TRPGQELYGQESDPALAALTALRLALSTDATVRIAAGDSLRADARTGLRADAALCHPPF FT NERNWGHDELAYDPRWEYGFPARTESELAWVQHALARVRDGGTVVVLMPPAAASRRSGR FT RVRADLLRRGALHAVIALPVGAAPPYNLPLHLWVLRRPERAPAQPGVLLADTGQFAGEG FT RGGPDWRSVRDAVLDAWTAFDRTGRLDDRPGLARCLPVIELLDDDVDLAPARHLPPPTA FT TGGTERLTDVRERLDETLRLTAELAPAAPGTGRAALRRPLTTVGELARGGALVLRTGTN FT GGHARVPLLTDHDVLTGTGPSGTLPEGDEEPVLTEPGDVVVPVLGGGSVARVIDADTAG FT AALGRNLVLLRPDPAALDPWFLAGFLRGTANHRQASSYASTATRLDVRRLQLPRLPLDA FT QRGYGDRFRALDEFERALRLAGRLGEQLARGMYDGLTDGTVAPD" FT RBS complement(53614..53617) FT CDS 53699..54304 FT /transl_table=11 FT /gene="SCO3105" FT /gene_synonym="SCE41.14" FT /product="hypothetical protein SCE41.14" FT /note="SCE41.14, unknown, len: 201 aa" FT /db_xref="UniProtKB/TrEMBL:Q9F2P5" FT /protein_id="CAC09546.1" FT /translation="MLTRFTSSGLIDPSDRPKRRASVHGRRSVSGERTDDMGMKTKIAL FT GAVVGIAVIGALSANAGDGDGGAKSDDRTSASAGEKQDGAGADGAKTDGASEAKPAEDK FT AAEKASQAEQFKAFVQKNGTPKEKDAVSHVTKVQGADEQNDILDAADVYTDFTGGIMGS FT GTGPAKLIASAFADWKDSENGLVTIYDADGELLGNGQF" FT CDS 54354..55253 FT /transl_table=11 FT /gene="SCO3106" FT /gene_synonym="SCE41.15" FT /product="putative lipoprotein" FT /note="SCE41.15, possible lipoprotein, len: 299 aa; similar FT to TR:CAB76294 (EMBL:AL158057) Streptomyces coelicolor FT putative lipoprotein SC10G8.21c, 249 aa; fasta scores: opt: FT 407 z-score: 384.9 E(): 6.2e-14; 31.1% identity in 241 aa FT overlap. Contains correctly situated match to Prosite entry FT PS00013 Prokaryotic membrane lipoprotein lipid attachment FT site and possible N-terminal region signal peptide FT sequence" FT /db_xref="UniProtKB/TrEMBL:Q9F2P4" FT /protein_id="CAC09547.1" FT /translation="MRRRARRTALTALLLAAGATACLTGCQSGQDGDGASDGAARSAAS FT GGSSAASPSATAPGSTAAPAEASASAPAPSPDEPFAGLSGAEISERALKATTGARSLRM FT TGSVPDDESGDTIEIDLALDRRGDCAGTMGMDGQGEAELIKTGDTVYLKYDERFLRAQS FT KGEPQADTEALVSLLAGRWTSMSADGADAKEMAGFCDLDKLLEDAGGSGDDAPTKVTRG FT RATTVDGKPAFTLYETDGSVRNTVYVATEGKPYLLRFESGSKQEPGALSFTGYDEPVPA FT EPPSGEVLDLDSPDGTST" FT misc_feature 54387..54419 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature 54468..54590 FT /note="high alanine, serine and proline amino acid residues FT content region" FT CDS complement(55321..56097) FT /transl_table=11 FT /gene="SCO3107" FT /gene_synonym="SCE41.16c" FT /product="putative lipoprotein" FT /note="SCE41.16c, possible lipoprotein, len: 258 aa; FT similar to TR:P95123 (EMBL:Z83018) Mycobacterium FT tuberculosis hypothetical 25.9 kDa protein MTCY349.15, 237 FT aa; fasta scores: opt: 498 z-score: 531.0 E(): 4.5e-22; FT 44.1% identity in 186 aa overlap. Contains correctly FT situated match to Prosite entry PS00013 Prokaryotic FT membrane lipoprotein lipid attachment site and possible FT N-terminal region signal peptide sequence" FT /db_xref="InterPro:IPR018532" FT /db_xref="UniProtKB/TrEMBL:Q9F2P3" FT /protein_id="CAC09548.1" FT /translation="MTRHSRIRTGWAAGAAALALALVTGCEGLEADGDAPASGGGAQAP FT AAGHAVSPLDNPDGTEPGLAPVTGDSPQAAARKLIDGLPTKGRGPKTGYDRDEFGYAWM FT DTADGVPLARNGCDTRNDLLKRDGQEVRFKSGSDCVVIAMTLDDPYTGTSIEWRKQKAS FT EVQIDHVVPLSYSWQMGSSRWPENKREQLANDPLNLLPVEGRANSAKRDSGPASWLPPD FT KAVRCAYAVRFAQVAAKYELAVTEADRAMMAKQCQG" FT misc_feature complement(56020..56052) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS complement(56105..56109) FT RBS 56232..56237 FT CDS 56244..56441 FT /transl_table=11 FT /gene="SCO3108" FT /gene_synonym="SCE41.17" FT /product="conserved hypothetical protein" FT /note="SCE41.17, conserved hypothetical protein, len: 65 FT aa; similar to TR:O05901 (EMBL:Z95210) Mycobacterium FT tuberculosis hypothetical 6.4 kDa protein MTCY21C12.03, 59 FT aa; fasta scores: opt: 102 z-score: 149.9 E(): 0.76; 29.3% FT identity in 58 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9F2P2" FT /protein_id="CAC09549.1" FT /translation="MGILDKMKSMAGKDKDKSRKMSDAAERQVNQRTGGKYEKQVDAAQ FT QQAEGKLGFGREQGGGREQQ" FT CDS complement(56559..60113) FT /transl_table=11 FT /gene="SCO3109" FT /gene_synonym="SCE41.18c" FT /product="putative transcriptional-repair coupling factor" FT /note="SCE41.18c, probable transcriptional-repair coupling FT factor, len: 1184 aa; similar to SW:MFD_ECOLI FT (EMBL:AE000211) Escherichia coli transcriptional-repair FT coupling factor Mfd, 1148 aa; fasta scores: opt: 2043 FT z-score: 2247.7 E(): 0; 37.5% identity in 1181 aa overlap . FT Contains Pfam match to entry PF00270 DEAD, DEAD/DEAH box FT helicase and PF00271 helicase_C, Helicases conserved FT C-terminal domain and match to Prosite entry PS00017 FT ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9F2P1" FT /db_xref="HSSP:1D9X" FT /db_xref="InterPro:IPR004576" FT /db_xref="UniProtKB/TrEMBL:Q9F2P1" FT /protein_id="CAC09550.1" FT /translation="MSLHGLLDAVVKDTALAEAIAAAADGNRMHVDLVGPPAARPFAIA FT ALARETGRPVLAVTATGREAEDLAAALRSLLPPEGIVEYPSWETLPHERLSPRSDTVGR FT RLAVLRRLAHPRPDDPETGPVSVVVAPVRSVLQPQVKGLGDLEPVALRTGQGADLEEIV FT QALAAAAYARVELVEKRGEFAVRGGILDVFPPTEEHPLRVEFWGDDVEEIRYFKVADQR FT SLEVAEHGLWAPPCRELLLTDDVRERARVLAEDHPELGELLGKIAEGIAVEGMESLAPV FT LVDDMELLLDVLPKGSMSVVCDPERVRTRAADLVATSQEFLQASWAATAGGGEAPIDVD FT AASLWSIADVRERARELDMMWWSVSPFAADETLTSDLDAEGDSDTLKLGMHAPETYRGD FT TAKALADTKGWLAEGWRAVYLTEGHGPASRTVEVLGGEGIAARLDNDLEALSPSVVHVS FT CGSIDHGFVDPALKLAVLTETDLTGQKAAGREGARMPARRRKTIDPLTLETGDYIVHEQ FT HGVGRYIEMVQRTVQGATREYLVVEYAPAKRGQPGDRLYIPTDQLEQITKYVGGEAPTL FT HRLGGADWTKTKARAKKAVKEIAADLIKLYSARMAAPGHAFGSDTPWQRELEDAFPYVE FT TPDQLTTIAEVKDDMEKTVPMDRLICGDVGYGKTEIAVRAAFKAVQDGKQVAVLVPTTL FT LVQQHFGTFSERYAQFPVSVKALSRFQSDTESKATLEGLREGSVDIVIGTHRLFSSETK FT FKDLGLVIVDEEQRFGVEHKEQLKKLRANVDVLTMSATPIPRTLEMAVTGIREMSTITT FT PPEERHPVLTFVGPYEHRQIGAAIRRELLREGQVFYIHNRVESIDRAAAKLREIVPEAR FT IATAHGQMSEQALEQVVVDFWEKKFDVLVSTTIVESGIDISNANTLIVERGDNFGLSQL FT HQLRGRVGRGRERGYAYFLYPPEKPLTETAHERLATIAQHTEMGAGMYVAMKDLEIRGA FT GNLLGGEQSGHIAGVGFDLYVRMVGEAVADYRASLEGGVEEEPPLEVKIELPVDAHVPH FT DYAPGERLRLQAYRSIASANSEEDVKAVREELVDRYGKLPEPVENLLLVAGLRMLARAC FT AVGEIVLQGNNIRFAPVELRESQELRLKRLYPGSVIKPGTHQVLVPRPKTAKVGGKPLV FT GRELLGWVGEFLTSILGS" FT misc_feature complement(57291..57545) FT /note="Pfam match to entry PF00271 helicase_C, Helicases FT conserved C-terminal domain, score 50.40, E-value 4e-11" FT misc_feature complement(57651..58241) FT /note="Pfam match to entry PF00270 DEAD, DEAD/DEAH box FT helicase, score 96.50, E-value 1.3e-29" FT misc_feature complement(58107..58130) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT repeat_region 60354..60412 FT /note="8x degenerate repeat unit: (A/G)CTC(G/A)(G/A)G" FT repeat_region 60454..60604 FT /note="10x degenerate repeat unit: FT (G/A)CT(T/C)(G/A)C(A/G)GGC(G/A)G(G/A/C)G" FT CDS complement(60750..63314) FT /transl_table=11 FT /gene="SCO3110" FT /gene_synonym="SCE41.19c" FT /product="putative ABC transport system integral membrane FT protein" FT /note="SCE41.19c, possible ABC transport system integral FT membrane protein, len: 854 aa; similar to TR:CAB96016 FT (EMBL:AL360055) Streptomyces coelicolor putative ABC FT transport system integral membrane protein SCG20A.11c, 855 FT aa; fasta scores: opt: 1429 z-score: 1454.6 E(): 0; 34.0% FT identity in 871 aa overlap. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q9F2P0" FT /db_xref="InterPro:IPR003838" FT /db_xref="UniProtKB/TrEMBL:Q9F2P0" FT /protein_id="CAC09551.1" FT /translation="MTVVKTSMRNFFAHKGRMALSAVAVLLSVAFVCGTLVFTDTMNTT FT FDKLFAVTSSDVSVAPKDVKDEDTPQNGVPESLPASTLEKIRSVDGVESVEGAVVSMNV FT TVVNSDNDNVGATSGAPTIAGNWTKNDLRSMEITSGHAPRGPTETMVDSDTADKHDLKI FT GDELRTIAQTGDFKAKIVGIASFTVTNPGAAVVYFDTATAQRELLGGADRFSQFNVTAA FT AGVTDAQLKQNVSGALGDTFKIQTAKEASDEGREDVGEFMDVIKYAMLGFAGIAFLVGI FT FLIINTFSMLVAQRTREIGLMRAIGSSRRQVNRSVLVEALLLGVVGSVLGVAAGVGIAI FT GLMKLMSAAGMNLSTDDLTIKTATPVTGLILGVVVTVLAAYLPARRAGKISPMAALRDA FT GTPADAKAGWIRGLIGLVLTGSGVAALLTAASADKASDGSMMLGAGIVLSLIGFVVIGP FT LLAGFVVRVISAVLLRAFGPVGRLAERNALRNPRRTGATGAALMIGLALVACLSVVGSS FT MVASATSELDKTVGADFIVQGNQRIVPQAEKAMTNTPGLEHVTRYKVLDATLTSPDGKT FT DDDGVTAADPTYAEDVRRATTEGELSAAYGTDAMSVGSDYAEKHGVHVGDTVSVAFKGG FT ETAKLKVAAITSDDVAIDQGARYISIETMQKYLPAENVPPNMIMFAKAKDGQADQAYAA FT LKKSLDAYPQYQVADQTDYKQELKDQIGQLLNMVYGLLALAIIVAVLGVVNTLALSVVE FT RTREIGLMRAIGLSRRQLRRMIRMESVVIALFGALLGLGLGMGWGATAQKLLALEGLNV FT LDIPWPTIIGVFIGSAFVGLFAALVPAFRAGRMNVLNAIATE" FT CDS complement(63311..64099) FT /transl_table=11 FT /gene="SCO3111" FT /gene_synonym="SCE41.20c" FT /product="putative ABC transport system ATP-binding FT protein" FT /note="SCE41.20c, possible ABC transport system ATP-binding FT protein, len: 262 aa; similar to TR: FT CAB89461(EMBL:AL354048) Streptomyces coelicolor putative FT ABC transporter ATP-binding protein SCE25.31, 256 aa; fasta FT scores: opt: 1240 z-score: 1356.4 E(): 0; 75.2% identity in FT 246 aa overlap. Contains Pfam match to entry PF00005 FT ABC_tran, ABC transporter and match to Prosite entry FT PS00017 ATP/GTP-binding site motif A (P-loop) and PS00211 FT ABC transporters family signature" FT /db_xref="GOA:Q9F2N9" FT /db_xref="HSSP:1F3O" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9F2N9" FT /protein_id="CAC09552.1" FT /translation="MTSAVSIPTHGSTGGRTAVAARARQVVKAYGSGETRVVALDHVDV FT DIARGQFTAIIGPSGSGKSTLMHCLAGLDTVTGGQIYLDETEITGLKDKKLTQLRRDRI FT GFIFQAFNLLPTLNAIENITLPMDIAGRKYDRAWLDRVVETVGLAGRLKHRPTQLSGGQ FT QQRVAVARALAAQPEIIFGDEPTGNLDSRAGAEVLGFLRRSVTELGQTIVMVTHDPVAA FT SYADRVLYLADGRIVDEMHKPTAEAVLDRMKDFDARGRTS" FT misc_feature complement(63398..63952) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 198.30, E-value 1.2e-55" FT misc_feature complement(63581..63625) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(63908..63931) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(64107..64111) FT CDS complement(<64825..>64929) FT /transl_table=11 FT /gene="SCO3112" FT /gene_synonym="SCE41.21c" FT /note="SCE41.21c, partial CDS, len: 105 bp. Transposase FT remnant. Similar to TR:Q9X8Z6 PUTATIVE TRANSPOSASE. FT Continuous with SCE41.22 when reversed" FT /db_xref="InterPro:IPR010095" FT /db_xref="UniProtKB/TrEMBL:Q9F2N8" FT /protein_id="CAC09553.1" FT /translation="PLQVREWTCTACGTVHDRDHNAAINVKQAAGLAAS" FT CDS <64930..>64995 FT /transl_table=11 FT /gene="SCO3113" FT /gene_synonym="SCE41.22" FT /note="SCE41.22, partial CDS, len: 66 bp. Transposase FT remnant. Similar to TR:Q9X8Z6 PUTATIVE TRANSPOSASE. FT Continuous with SCE41.21c when reversed" FT /db_xref="UniProtKB/TrEMBL:Q9F2N7" FT /protein_id="CAC09554.1" FT /translation="ACGAPVSPGAIPAQREETGSHG" FT CDS complement(65604..66500) FT /transl_table=11 FT /gene="SCO3114" FT /gene_synonym="SCE41.23c" FT /product="conserved hypothetical protein" FT /note="SCE41.23c, conserved hypothetical protein, len: 298 FT aa; similar to TR:O07481 (EMBL:Z97071) Streptomyces FT reticuli AbpS protein, 311 aa; fasta scores: opt: 482 FT z-score: 473.6 E(): 7.1e-19; 35.0% identity in 294 aa FT overlap. Contains various coiled-coil regions at approx. FT residues 42..60 and 207..251" FT /db_xref="UniProtKB/TrEMBL:Q9F2N6" FT /protein_id="CAC09555.1" FT /translation="MSGASASPHGFATVRGRERGYRPEQVEACAAALSEERDAAWERAA FT RLTVLAREMEEDLGDLEEVVAQLTSQDYEVLGERARELFRLGEEEAAAVRERARGAARE FT LAEEARAYADGVREAARAHADAVRAEADERARQLLLAARAEADEARIGARRDVKEGRAE FT ALSALREMRRRTAATAAEQSRELAERWAAAERAEEERARALDAHHAELLARAEQGVREA FT EQELADAGEAAVRRQEEARDRAAEVVAEARARRERIARDTERVLREHGERWDELQAHMA FT SVRSSLQALTGRAVEVE" FT RBS complement(66511..66514) FT stem_loop complement(66632..66673) FT /note="possible stem loop. Score 54: 18/18 (100%) matches, FT 0 gaps" FT CDS complement(66701..69370) FT /transl_table=11 FT /gene="SCO3115" FT /gene_synonym="SCE41.24c" FT /product="hypothetical protein SCE41.24c" FT /note="SCE41.24c, unknown, len: 889 aa. High content in FT alanine, glycine and proline amino acid residues. Contains FT 20x degenerate repeat: (G/P/A/N)P(G/P/A)" FT /db_xref="UniProtKB/TrEMBL:Q9F2N5" FT /protein_id="CAC09556.1" FT /translation="MVTFAQAQERAEEWVNGELPAYQHREVRVREFDLGFVVWAEDRAD FT GPRSDGGAQRLVIARDSGEATLWPSLPVGEVIRRYEEEYGRPEEAQAPAAAPAARVDLN FT QTSFLLSPPEWLQEAADRIGIPDRRRGDGEAGATGGAGGSGGALPQTQAGVPAAPAASG FT PSPAGGSSGSGAGWPAAGSGSSAGGSGADAGASGAPSAPGVPAGATPWAGTDTNADAGD FT DRSVPLPQTVFAPPLSGVDDDTPPPSTTSDAKTALMSGGSGLPPTALSPAIGDPNAPGA FT PAGAGTPPPAAPTAPPAQPPAGPGAPATPPRPLAPDAGDIADAATSKATPPPRRGGGSS FT TPPPPSAPGMPGARPGSTPAPSGPPAPGAPAGGYVPTQLVSSLGPEGPGGPGTPPPPSA FT PATPPAPGATPPPGTPGTPPPPPPSAPNAPGGTPPGGMHHAATMLADPGRTGGGAPQPP FT GPPGPPNPPGPPGPPGAPAAPGAPGAPGVPSGPGVPPPPPGAPGAQGSAGGAGGAVHHA FT QTVLAAPSLGGPGGIGAPPPPPGAVPPPPGQPVPGQPPAYGYPPQPTGQPTVGPGYQAV FT LRYRAQDGSEQQLIRRSAPGTPHPEWQMFHELRSMNVPPDQVLELHTELESCELPGAYC FT ARMIREQWPQARITSIAPYGLDHASRQQGMGQLLAHQGELHQVADGPARPAPVRAPLPQ FT VQPAPPVPPEAVGQELAGAFGPGVFRFEQAAVSRQGVPPVVAHTLVAAGLPMDMGPFFW FT AQAQPGRPVPTLAELAAERGVQPASDAGSYLVVGSDFGRAICVQYGTAAIVAVPVEAGP FT GGAPVPPQFVNTGLPEFARCLALLGRMWRLRFGLNQEQAGRWTVDFQAQLAALDPAALG FT SPESWWSVLLEQMWDGLL" FT repeat_region complement(67730..68140) FT /note="degenerate repeat translated in SCE41.23c" FT misc_feature complement(68747..68980) FT /note="high in alanine, glycine, proline and serine amino FT acid residues region" FT CDS complement(69378..70385) FT /transl_table=11 FT /gene="SCO3116" FT /gene_synonym="SCE41.25c" FT /product="hypothetical protein SCE41.25c" FT /note="SCE41.25c, unknown, len: 335 aa" FT /db_xref="InterPro:IPR018958" FT /db_xref="UniProtKB/TrEMBL:Q9F2N4" FT /protein_id="CAC09557.1" FT /translation="MTTGRLGQAAAPPNAAYAGQVVHFPDPVRAARHPRGVRVDAGGYP FT EFSPYARAVAEIADPPEGFGVDELRLTDYVSANAVLSASGHELWDTVPAVATPHGWTWH FT HVAGSRRMELVPVEVKALLRHHGGISTAVVDQGKRGTRPLQETRPVHFGLPKSGVAVTE FT QQVQGVEEDLGYRLPGAYRSFLKAAGGCAPVGTALDAELGLLVDQPFFTVREEAAVNDL FT VYVNKCLRDHLTKDYLGVAFVQGGLLAVKVKGERIGSVWFCAYDDVRDVDPSWPPADRV FT ERLLLPCGADFDAFLSRLAGSPPELETVANLMVDGGFARAVPVTAASSASSVGE" FT RBS 70661..70667 FT CDS 70679..71209 FT /transl_table=11 FT /gene="SCO3117" FT /gene_synonym="SCE41.26" FT /product="hypothetical protein SCE41.26" FT /note="SCE41.26, unknown, len: 176 aa" FT /db_xref="UniProtKB/TrEMBL:Q9F2N3" FT /protein_id="CAC09558.1" FT /translation="MSATQTGPDTGRSDDPRGGDPRIGWSSTDTLQTPALRHRRDGILP FT TVAAALSVRGTTLTGTATRADTPPALHHLVQDFLDTLTSGQRDRYTGRCAETILISRHL FT ATADAARSKRAARKPMTNGEARKALKHAKLTTRRIREDGDPLHGAFAAPCRACTALSAH FT FGVRVVDPATEKD" FT CDS 71302..71799 FT /transl_table=11 FT /gene="SCO3118" FT /gene_synonym="SCE41.27" FT /product="hypothetical protein SCE41.27" FT /note="SCE41.27, unknown, len: 165 aa" FT /db_xref="UniProtKB/TrEMBL:Q9F2N2" FT /protein_id="CAC09559.1" FT /translation="MQADRTSTTRFPVPVDAALRDAGWQPGRWDIKQAEIWADTLREHS FT SPAGHRHTVFPAAVEAWAEFGGLHIAPTGPGRQIAPATLHLDPLHGLHMARTLGDLGRA FT LGTQTCPLGTETDSRALVAIDAEGRVYALDHTGDWYLGSDIDAALATLVAGTQPARLTT FT TG" FT CDS complement(71821..73140) FT /transl_table=11 FT /gene="SCO3119" FT /gene_synonym="SCE41.28c" FT /note="SCE41.28c, possible sensor kinase, len: 439 aa; FT similar to TR:O86631 (EMBL:AL031155) Streptomyces FT coelicolor two-component sensor SC3A7.30, 429 aa; fasta FT scores: opt: 296 z-score: 316.7 E(): 3.9e-10; 32.9% FT identity in 395 aa overlap. Contains possible hydrophobic FT membrane spanning regions at N-terminal domain" FT /db_xref="GOA:Q9F2N1" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9F2N1" FT /protein_id="CAC09560.1" FT /translation="MTTTGEDHEPARGGPWWWDRRRGAVLDVSLGVVSALECAAEGVPF FT ARDAGIPPAMGVVFGLLAGSMLVVRRKWPIAVVLVALAITPAEMGFLMGVVGLYTMAAS FT ELPRRIIGALAGMTFLGTLVVTFVRLGQDMARDGLDLGDWFLPFASIATSLGMTAPPLL FT LGLYVGQRRRLMESLRERADSLERELQLLAERAEERAEWARGEERTRIAREMHDVVAHR FT VSLMVVHAAALQAIARKDPEKAVKNAALVGDMGRQALTELREMLGVLRSGGGGARAERA FT SVPLAAVGVAAAAAASRAAEDGESSSEGPCLSELDELIGQSEAAGMVVNLSVEGAERAY FT AAEVESTAFRVVQEALTNVHKHAAGAKTHVRLAHRVSEIAMQVENEPPPEVSSASSARL FT PSGGNGLVGMKERVAALGGVFVSGPTDAGGFRVSAVIPAS" FT RBS complement(73142..73146) FT CDS complement(73649..73858) FT /transl_table=11 FT /gene="SCO3120" FT /gene_synonym="SCE41.29c" FT /product="hypothetical protein SCE41.29c" FT /note="SCE41.29c, unknown, len: 69 aa" FT /db_xref="UniProtKB/TrEMBL:Q9F2N0" FT /protein_id="CAC09561.1" FT /translation="MALESRLVEGAAIGADEFGPELLRACRIGVLVMLGSLLTKTTFSR FT RSYGLVLAPFRPVQAYAHREEFAG" FT CDS 73871..73999 FT /transl_table=11 FT /gene="SCO3121" FT /gene_synonym="SCE41.30" FT /product="hypothetical protein SCE41.30" FT /note="SCE41.30, unknown, len: 42 aa. Doubtful CDS, TBparse FT predicted" FT /db_xref="UniProtKB/TrEMBL:Q9F2M9" FT /protein_id="CAC09562.1" FT /translation="MRKNAGDSSRGCLAIKVLKSADLYRRIEGSWYGIVLGADSAT" FT tRNA 74027..74099 FT /note="tRNA Pseudo anticodon TTG, Cove score 42.02" FT CDS 74209..75657 FT /transl_table=11 FT /gene="SCO3122" FT /gene_synonym="SCE66.01" FT /gene_synonym="SCE41.31" FT /product="putative nucleotidyltransferase" FT /note="SCE66.01, probable nucleotidyltransferase, partial FT CDS, len: >343 aa; similar to many eg.. SW:P14192 FT (GCAD_BACSU) UDP-N-acetylglucosamine pyrophosphorylase from FT Bacillus subtilis (456 aa) fasta scores; opt: 895, FT z-score: 1020.4, E(): 0, 42.6% identity in 317 aa overlap. FT Contains five Pfam matches to entry PF00132 hexapep, FT Bacterial transferase hexapeptide." FT /note="SCE41.31, probable nucleotidyltransferase FT (fragment), len: >174 aa; similar to SW:GLMU_ECOLI FT (EMBL:X01631) Escherichia coli UDP-N-acetylglucosamine FT pyrophosphorylase (EC 2.7.7.23) GlmU, 456 aa; fasta scores: FT opt: 369 z-score: 411.5 E(): 2.1e-15; 42.4% identity in 165 FT aa overlap" FT /db_xref="GOA:Q8CJX6" FT /db_xref="HSSP:1HM0" FT /db_xref="InterPro:IPR005882" FT /db_xref="UniProtKB/Swiss-Prot:Q8CJX6" FT /protein_id="CAD55493.1" FT /translation="MSAIRPAAVVVLAAGEGTRMKSATPKVLHELCGRSLVGHVLAAAG FT ELDPENLVAVVGHAREKVTAHLAEVAPDVRTAVQEQQNGTGHAVRMGLEAMGGAVDGVV FT VVVCGDTPLLTGETLKALAATHTADGNAVTVLTAEVPDATGYGRIVRDGASGAVTAIVE FT HKDASESQRAIREINSGVFAFDGQLLADALGKVRTDNSQGEEYLTDVLGILREAGHRVG FT ASVAGDHREIAGINNRVQLAEARRILNDRLLTGAMLAGVTVVDPATTWVDVTVTFEQDV FT VVHPGTQLHGTTHLAEGCEVGPNTRLTDTRVEAGARVDNTVANGAHVGPQASVGPYAYL FT RPGTRLGLKSKIGTFVEAKNSSIGEGTKVPHLSYMGDATVGDFTNIGAASVFVNYDGQD FT KHHTTIGSHCRTGSDNMFVAPVTVGDGAYTAAGSVITKDVPPGSLAVARGQQRNIEGWV FT ARKRPGSAAAKAAEAVSREADGED" FT misc_feature 75028..75081 FT /note="Pfam match to entry PF00132 hexapep, Bacterial FT transferase hexapeptide (four repeats), score 6.20, E-value FT 1.1e+02" FT misc_feature 75082..75135 FT /note="Pfam match to entry PF00132 hexapep, Bacterial FT transferase hexapeptide (four repeats), score 8.40, E-value FT 55" FT misc_feature 75181..75234 FT /note="Pfam match to entry PF00132 hexapep, Bacterial FT transferase hexapeptide (four repeats), score 7.90, E-value FT 65" FT misc_feature 75286..75339 FT /note="Pfam match to entry PF00132 hexapep, Bacterial FT transferase hexapeptide (four repeats), score 3.80, E-value FT 2.3e+02" FT misc_feature 75466..75519 FT /note="Pfam match to entry PF00132 hexapep, Bacterial FT transferase hexapeptide (four repeats), score 6.80, E-value FT 93" FT RBS 75776..75780 FT CDS 75789..76763 FT /transl_table=11 FT /gene="SCO3123" FT /gene_synonym="prsA2" FT /gene_synonym="SCE66.02" FT /product="ribose-phosphate pyrophosphokinase" FT /note="SCE66.02, prsA2, ribose-phosphate pyrophosphokinase FT (EC 2.7.6.1), len: 324 aa; strongly similar to many eg. FT SW:P14193 (KPRS_BACSU) ribose-phosphate pyrophosphokinase FT from Bacillus subtilis (317 aa) fasta scores; opt: 1000, FT z-score: 1178.1, E(): 0, 46.8% identity in 314 aa overlap. FT Contains Pfam match to entry PF00156 Pribosyltran, FT Phosphoribosyl transferase domain and Prosite match to FT PS00103 Purine/pyrimidine phosphoribosyl transferases FT signature." FT /db_xref="GOA:Q9K3U0" FT /db_xref="HSSP:1DKR" FT /db_xref="InterPro:IPR005946" FT /db_xref="UniProtKB/Swiss-Prot:Q9K3U0" FT /protein_id="CAB95916.1" FT /translation="MTGIKTTGEKKMMFFSGRAHPELAEEVAQQLGVGVVPTKAFDFAN FT GEIYVRYQESARGADCFLIQSHTAPINKWVMEQLIMIDALKRASARSITVIVPFYGYAR FT QDKKHRGREPISARLIADLMKTAGADRILAVDLHTDQIQGFFDGPVDHLFALPLLADYV FT GAKVDRSKLTVVSPDAGRVRVADRWCDRLGAPLAIVHKRRDKDVANQVTVHEVVGDVKG FT RICVLVDDMIDTGGTICAAADALFAHGAEDVIVTATHGVLSGPAADRLKNSKVSEFVFT FT NTLPSASELELDKITVLSIAPTIARAVREVFEDGSVTSLFDEQ" FT misc_feature 76215..76631 FT /note="Pfam match to entry PF00156 Pribosyltran, FT Phosphoribosyl transferase domain, score 100.60, E-value FT 3e-26" FT misc_feature 76461..76499 FT /note="PS00103 Purine/pyrimidine phosphoribosyl FT transferases signature" FT stem_loop 76816..76875 FT /note="Score 52: 20/22 ( 90%) matches, 0 gaps, 16 base FT loop" FT RBS 76966..76970 FT CDS 76976..77572 FT /transl_table=11 FT /gene="SCO3124" FT /gene_synonym="SCE66.03" FT /product="ribosomal L25p family protein" FT /note="SCE66.03, ribosomal L25p family protein, len: 198 FT aa; similar to many members of the ribosomal L25p family FT (includes ribosomal protein, general stress proteins and FT glutaminyl-tRNA synthetases) eg. SW:P14194 (CTC_BACSU) FT general stress protein from Bacillus subtilis (203 aa) FT fasta scores; opt: 327, z-score: 393.9, E(): 1.8e-14, 31.6% FT identity in 196 aa overlap. Contains Pfam match to entry FT PF01386 Ribosomal_L25p, Ribosomal L25p family and Prosite FT match to PS00017 ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q9K3T9" FT /db_xref="HSSP:1DFU" FT /db_xref="InterPro:IPR020055" FT /db_xref="UniProtKB/Swiss-Prot:Q9K3T9" FT /protein_id="CAB95917.1" FT /translation="MSEVKLTAETRTEFGKGAARRIRRDNKVPGVLYGHGSDPLHLTLP FT GHELLLALRTSNVLIALDIDGKTNELAIPKSVQRDPIKGFLEHVDLQLVKRGETVSVEI FT PVQAEGELAPGGFLLEYVLDALPVEAEATHIPQQVTVSVAGLEAGASIHAKDIALPSGV FT KLDVDGDTVVLQVLSAQAEEAPAEGEGEGEGAAEA" FT misc_feature 76991..77248 FT /note="Pfam match to entry PF01386 Ribosomal_L25p, FT Ribosomal L25p family, score 94.50, E-value 2.2e-24" FT misc_feature 77156..77179 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 77670..77675 FT CDS 77678..78280 FT /transl_table=11 FT /gene="SCO3125" FT /gene_synonym="pth" FT /gene_synonym="SCE66.04" FT /product="peptidyl-tRNA hydrolase" FT /note="SCE66.04, pth, peptidyl-tRNA hydrolase (EC FT 3.1.1.29), len: 200aa; strongly similar to many eg. FT SW:P23932 (PTH_ECOLI) peptidyl-tRNA hydrolase from FT Escherichia coli (194 aa) fasta scores; opt: 449, z-score: FT 529.8, E(): 4.9e-22, 41.1% identity in 185 aa overlap. FT Contains Pfam match to entry PF01195 Pept_tRNA_hydro, FT Peptidyl-tRNA hydrolase and Prosite match to PS01196 FT Peptidyl-tRNA hydrolase signature 2." FT /db_xref="GOA:Q9K3T8" FT /db_xref="HSSP:2PTH" FT /db_xref="InterPro:IPR001328" FT /db_xref="UniProtKB/Swiss-Prot:Q9K3T8" FT /protein_id="CAB95918.1" FT /translation="MDVTTDAGAPWLVAGLGNPGPEYASNRHNVGFMVADLLAERIGAR FT FKRHGKAQAQVVEGRIGPPGPANRRVILAKPMSFMNVSGGPVTALRDFYKVPVGNIVAV FT HDELDIDYGVLRLKLGGGDNGHNGLKSITKSLGADYHRVRFGIGRPPGRMPVADFVLRD FT FSSTERKELDYFVDRAADAVEALVIEGLERAQSAYNS" FT misc_feature 77708..78274 FT /note="Pfam match to entry PF01195 Pept_tRNA_hydro, FT Peptidyl-tRNA hydrolase, score 261.90, E-value 8.4e-75" FT misc_feature 78041..78073 FT /note="PS01196 Peptidyl-tRNA hydrolase signature 2" FT CDS 78333..78851 FT /transl_table=11 FT /gene="SCO3126" FT /gene_synonym="SCE66.05" FT /product="putative membrane protein" FT /note="SCE66.05, possible membrane protein, len: 172aa; FT contains possible membrane-spanning hydrophobic regions." FT /db_xref="UniProtKB/TrEMBL:Q9K3T7" FT /protein_id="CAB95919.1" FT /translation="MIPAMPASAAAARPRQASSVSSVLLRFGRVASMGTVTALILIAGV FT WASWGTAQHVLLTKGREQGTVEVTRCGGGTCSGPYSPVSAGSQARERVVLEDSVAVAKG FT RTYSVVLKPGSADAVRSGPAGVLYAWVPLGGALLLASVVVAGGLRRTRAGWVMAGAGVA FT LLTAAFVAV" FT stem_loop 78869..78917 FT /note="Score 59: 21/22 ( 95%) matches, 0 gaps, 6 base loop" FT misc_feature complement(78921..82845) FT /note="Region previously sequenced as EMBL:AF177946" FT CDS complement(78932..81667) FT /transl_table=11 FT /gene="SCO3127" FT /gene_synonym="ppc" FT /gene_synonym="SCE66.06c" FT /product="phosphoenolpyruvate carboxylase" FT /note="SCE66.06c, ppc, phosphoenolpyruvate carboxylase (EC FT 4.1.1.31), len: 911 aa; previously sequenced as TR:Q9RNU9 FT (EMBL:AF177946). Strongly similar to many others eg. FT SW:O32483 (CAPP_RHOPA) from Rhodopseudomonas palustris (936 FT aa) fasta scores; opt: 1801, z-score: 1974.8, E(): 0, FT 38.4% identity in 948 aa overlap. Contains Pfam match to FT entry PF00311 PEPcase, Phosphoenolpyruvate carboxylase and FT Prosite match to PS00781 Phosphoenolpyruvate carboxylase FT active site 1." FT /db_xref="GOA:Q9RNU9" FT /db_xref="HSSP:1JQN" FT /db_xref="InterPro:IPR015813" FT /db_xref="UniProtKB/Swiss-Prot:Q9RNU9" FT /protein_id="CAB95920.1" FT /translation="MSSADDQTTTTTSSELRADIRRLGDLLGETLVRQEGPELLELVEK FT VRRLTREDGEAAAELLRGTELETAAKLVRAFSTYFHLANVTEQVHRGRELGAKRAAEGG FT LLARTADRLKDADPEHLRETVRNLNVRPVFTAHPTEAARRSVLNKLRRIAALLDTPVNE FT SDRRRLDTRLAENIDLVWQTDELRVVRPEPADEARNAIYYLDELHLGAVGDVLEDLTAE FT LERAGVKLPDDTRPLTFGTWIGGDRDGNPNVTPQVTWDVLILQHEHGINDALEMIDELR FT GFLSNSIRYAGATEELLASLQADLERLPEISPRYKRLNAEEPYRLKATCIRQKLENTKQ FT RLAKGTPHEDGRDYLGTAQLIDDLRIVQTSLREHRGGLFADGRLARTIRTLAAFGLQLA FT TMDVREHADAHHHALGQLFDRLGEESWRYADMPREYRTKLLAKELRSRRPLAPSPAPVD FT APGEKTLGVFQTVRRALEVFGPEVIESYIISMCQGADDVFAAAVLAREAGLIDLHAGWA FT KIGIVPLLETTDELKAADTILEDLLADPSYRRLVALRGDVQEVMLGYSDSSKFGGITTS FT QWEIHRAQRRLRDVAHRYGVRLRLFHGRGGTVGRGGGPTHDAILAQPWGTLEGEIKVTE FT QGEVISDKYLIPALARENLELTVAATLQASALHTAPRQSDEALARWDAAMDVVSDAAHT FT AYRHLVEDPDLPTYFLASTPVDQLADLHLGSRPSRRPGSGVSLDGLRAIPWVFGWTQSR FT QIVPGWYGVGSGLKALREAGLDTVLDEMHQQWHFFRNFISNVEMTLAKTDLRIAQHYVD FT TLVPDELKHVFDTIKAEHELTVAEVLRVTGESELLDADPVLKQTFTIRDAYLDPISYLQ FT VALLGRQREAAAANEDPDPLLARALLLTVNGVAAGLRNTG" FT misc_feature complement(79028..81316) FT /note="Pfam match to entry PF00311 PEPcase, FT Phosphoenolpyruvate carboxylase, score 359.40, E-value FT 2.3e-107" FT misc_feature complement(81236..81271) FT /note="PS00781 Phosphoenolpyruvate carboxylase active site FT 1" FT RBS complement(81676..81681) FT RBS 81966..81970 FT CDS 81974..82984 FT /transl_table=11 FT /gene="SCO3128" FT /gene_synonym="SCE66.07" FT /product="putative fatty acid desaturase (membrane)" FT /note="SCE66.07, possible fatty acid desaturase (membrane), FT len: 336 aa; similar to many (mainly eukaryotic) e.g. FT SW:O00767 (ACOD_HUMAN) acyl-CoA desaturase (EC 1.14.99.5) FT from Homo sapiens (Human) (359 aa) fasta scores; opt: 409, FT z-score: 480.0, E(): 2.9e-19, 29.7% identity in 330 aa FT overlap. Contains Pfam match to entry PF01069 Desaturase, FT Fatty acid desaturase and possible membrane-spanning FT hydrophobic regions." FT /db_xref="GOA:Q9K3T6" FT /db_xref="InterPro:IPR015876" FT /db_xref="UniProtKB/TrEMBL:Q9K3T6" FT /protein_id="CAB95921.1" FT /translation="MTTSSDVIPDAPQPAGDAAGPSATLGGEQKRSIEQITLLLFITLP FT FLALVAAVPLAWGWGVSWLDLGLLVFFYFLGCHGITIGFHRHFTHGSFKAKRPLKIALA FT IAGSMAVEGPLVRWVADHRKHHKFSDDEGDPHSPWRYGETVPALIKGLWWAHIAWMFDE FT EQTPQEKYAPDLIKDPALRAVSRQFILWTVVSLALPALIGGLVTMSWWGAFTGFFWGSL FT VRVALLHHVTWSINSICHAVGKRPFKSRDRSGNVWWLAILSCGESWHNLHHADPTSARH FT GVMRGQLDSSARLIRWFEQLGWAYDVRWPSRSRIDSRRNTDQDGARRRKETAKAA" FT misc_feature 82088..82849 FT /note="Pfam match to entry PF01069 Desaturase, Fatty acid FT desaturase, score 198.40, E-value 1.1e-55" FT RBS 82973..82979 FT CDS 82981..83658 FT /transl_table=11 FT /gene="SCO3129" FT /gene_synonym="SCE66.08" FT /product="putative TetR-family transcriptional regulator" FT /note="SCE66.08, possible TetR-family transcriptional FT regulator, len: 225 aa; similar to many proposed FT transcriptional regulators e.g. TR:Q9RYK4 (EMBL:AE001863) FT transcriptional regulator, TetR-family from Deinococcus FT radiodurans (239 aa) fasta scores; opt: 318, z-score: FT 386.8, E(): 4.6e-14, 32.7% identity in 208 aa overlap. Also FT similar to TR:P96381 (EMBL:Z92539) hypothetical protein FT from Mycobacterium tuberculosis (197 aa) fasta scores; opt: FT 827, z-score: 991.9, E(): 0, 64.4% identity in 194 aa FT overlap. Contains Pfam match to entry PF00440 tetR, FT Bacterial regulatory proteins, tetR family and FT helix-turn-helix motif (Score 1473 (+4.20 SD) in SCE66.08 FT at residues 51-72" FT /db_xref="GOA:Q9K3T5" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9K3T5" FT /protein_id="CAB95922.1" FT /translation="MIDAVATDSSSTPSNEKPRRARRTRMTGAERRQQLLEIGRTLFAA FT KGFEGTSVEEIAAKAGVSKPVVYEHFGGKEGLYAVVVDREMRRLLDMVTGSLTAGHPRE FT LCEQAAFALLDYIEEYTDGFRILVRDSPIPQSTGTFASLISDIATQVEDILGREFKNRG FT FDAKLAPLYAQALVGMVALTGQWWLDVRRPKKAEVAAHLVNLAWHGLDGLEPKPRLIGH FT RKS" FT misc_feature 83083..83223 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 64.10, E-value FT 3e-15" FT RBS 83685..83688 FT CDS 83691..84866 FT /transl_table=11 FT /gene="SCO3130" FT /gene_synonym="SCE66.09" FT /product="putative dehydratase" FT /note="SCE66.09, possible dehydratase, len: 391 aa; similar FT to many e.g. SW:P31572 (CAIB_ECOLI) L-carnitine dehydratase FT from Escherichia coli (405 aa) fasta scores; opt: 440, FT z-score: 478.4, E(): 3.6e-19, 28.7% identity in 401 aa FT overlap." FT /db_xref="GOA:Q9K3T4" FT /db_xref="HSSP:1PQY" FT /db_xref="InterPro:IPR003673" FT /db_xref="UniProtKB/TrEMBL:Q9K3T4" FT /protein_id="CAB95923.1" FT /translation="MQPLRGVTVVALEQAIAAPYASRQLADLGARVIKVERPRTGDFAR FT AYDTRVRGLSSHFVWANRNKESLTLDFKDPRGLELLRRLIADADVFLQNLAPGAAARAG FT LGARELRAAHPELIVCDISGYGTPGPYADRKAYDLLVQSEAGLLSVTGTPDDMAKAGIP FT VSDIAAGMYAYSSVLGALLERGRTGRGTHLDVSMLEATVEWLGFPLYYAFEGGRPPPRA FT GASHATIYPYGPFTAGDGKVVMTAVQNEREWQGFCAGFLDRPELAGHPHYATNADRNAH FT REELGALIAARFARLTAAEAVELLDAVPVANARVNTLAEVWDHPQLAARGRLHEVPTPA FT GPVPALAPPGPTGDAPRMEAVPALGEHTRAVLGGLGLSEQDIDALAADGVV" FT CDS complement(84879..85256) FT /transl_table=11 FT /gene="SCO3131" FT /gene_synonym="SCE66.10c" FT /product="conserved hypothetical protein" FT /note="SCE66.10c, unknown, len: 125aa; similar to TR:Q9RY42 FT (EMBL:AE001873) hypothetical protein from Deinococcus FT radiodurans" FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/TrEMBL:Q9K3T3" FT /protein_id="CAB95924.1" FT /translation="MITGLDHVQLAVPPGAEEPLRAFYTGVLGMSEVPKPPVLAVHGGC FT WFRAGAVHLHLGVETAGFRPARKAHPGLRVTGIDAYAARLEAHGTPVTWDHDLPGHRRF FT YCADPVGNRLEFLEPVGPARP" FT CDS complement(85253..86164) FT /transl_table=11 FT /gene="SCO3132" FT /gene_synonym="SCE66.11c" FT /product="putative trans-aconitate methyltransferase" FT /note="SCE66.11c, possible trans-aconitate FT methyltransferase, len: 303 aa; similar to many e.g. FT SW:TAM_ECOLI (EMBL:AE000249) trans-aconitate FT methyltransferase from Escherichia coli (251 aa) fasta FT scores; opt: 707, z-score: 686.9, E(): 8.8e-31, 43.9% FT identity in 269 aa overlap. Contains degenerately FT repetative glycine-rich sequence at the C-terminus." FT /db_xref="GOA:Q9K3T2" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/Swiss-Prot:Q9K3T2" FT /protein_id="CAB95925.1" FT /translation="MPATAPTWDPAQYLRHAGHRARPFTDLLARIPDLPADPPRIADLG FT CGPGNVTVLLADRWPTARITGYDNSPRMLERARQYAGPTSGGGHLDFAPADARSWTPDE FT PCDLLVSNATLQWVPGHADLFPGWIDRLAPGGTLALQVPGNFDAPSHRLMRELADSRRW FT RERLAGVLRHDDAVLTPEGYLAHLTAAGCTADVWETTYVHLLPGDDAVLDWVRGTGLRP FT VLDALDGDPAARDAFVDEYRAVLRAAYPAQAHGTPFPFRRVFAVARKPEGSGGSGGSGG FT SAGSAGCAGSGGSVGPAGEAGR" FT RBS complement(85261..85266) FT RBS complement(86169..86173) FT CDS 86329..86826 FT /transl_table=11 FT /gene="SCO3133" FT /gene_synonym="SCE66.12" FT /product="putative MarR-family regulator" FT /note="SCE66.12, probable MarR-family regulator, len: 165 FT aa; similar to many e.g. SW:P42195 (PECS_ERWCH) regulatory FT protein PecS from Erwinia chrysanthemi (166 aa) fasta FT scores; opt: 412, z-score: 499.8, E(): 2.3e-20, 42.7% FT identity in 150 aa overlap. Contains Pfam match to entry FT PF01047 MarR, MarR family." FT /db_xref="GOA:Q9K3T1" FT /db_xref="InterPro:IPR000835" FT /db_xref="UniProtKB/TrEMBL:Q9K3T1" FT /protein_id="CAB95926.1" FT /translation="MEDEVDRLVAAWRRERPDLDVEPLEVLSRVSRLARHLDRARRLAF FT SEHNLEPWEFDVLTALRRAGTPYQLSPGQLLTQTLVTSGTMTNRIDRLAKKGLVERLPD FT PSDRRGVLVRLTDEGRDRADQSLAGLLAQERAILGELSRAQRTELAALLRQLTAPFDNI FT PG" FT misc_feature 86476..86796 FT /note="Pfam match to entry PF01047 MarR, MarR family, score FT 87.70, E-value 2.3e-22" FT CDS complement(86785..87741) FT /transl_table=11 FT /gene="SCO3134" FT /gene_synonym="SCE66.13c" FT /product="putative two-component system response regulator" FT /note="SCE66.13c, possible two-component system response FT regulator, len: 318 aa; similar to many proposed regulators FT e.g. TR:Q9RI42 (EMBL:AL109989) putative LuxR family FT two-component response regulator (233 aa) fasta scores; FT opt: 299, z-score: 339.4, E(): 2e-11, 31.6% identity in 234 FT aa overlap. Contains Pfam match to entry PF00072 FT response_reg, Response regulator receiver domain, Pfam FT match to entry PF00196 GerE, Bacterial regulatory proteins, FT luxR family and helix-turn-helix motif (Score 1492 (+4.27 FT SD) in SCE66.13c at residue 253-274)." FT /db_xref="GOA:Q9K3T0" FT /db_xref="HSSP:1FSE" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9K3T0" FT /protein_id="CAB95927.1" FT /translation="MSSTGGGRCRSGGETAGFDAREQHSWTRAPASTRAGAVVRGRTDD FT GYPLLLAELGGGGFVVRIRVLVVDDHRIFAESLAAALAAEPDVDVSAAGSGPAALRCLE FT RAASEGRRFDVLLVDADLGGHVPGVRPAVPVRDGNEDGLVDGISLVAGVRSGQPGVRTV FT VLAEKDDPRRAALALGAGASGWVAKDCSLSRLLSVIRGVLRDETHLPPALLTGVLRELT FT AARKHRTESELLVESLTPREREVLRCMVAGLGRKAVAERLYLSPHTVRTHMQNVLGKLG FT VHSTLAAVALARRAGVGPADLDGPSAGDVVERGGQLA" FT misc_feature complement(86842..87039) FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 86.00, E-value FT 7.8e-22" FT misc_feature complement(87145..87555) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 59.00, E-value 1e-13" FT CDS 87804..88259 FT /transl_table=11 FT /gene="SCO3135" FT /gene_synonym="SCE66.14" FT /product="putative acetyltransferase" FT /note="SCE66.14, probable acetyltransferase, len: 151 aa; FT similar to many especially SW:P19997 (BLS_STRSJ) FT blasticidin S-acetyltransferase (confers resistance to FT blasticidin S antibiotic) from Streptoverticillium sp. FT (strain JCM4673) (136 aa) fasta scores; opt: 465, z-score: FT 599.3, E(): 6.6e-26, 57.3% identity in 131 aa overlap. FT Contains Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family." FT /db_xref="GOA:Q9K3S9" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9K3S9" FT /protein_id="CAB95928.1" FT /translation="MVSRMFRLVTEVDRERRDLLRTRLRETNTAASSVLRSLRGTPHER FT EFPLHVWVLDATGGLAGGLVGHTWATWLHVTYLWVDGGHRGAGLGSALLDEAERTARTE FT RGCAAARVETWDFQAPGFYTKRGYDVMCVIPDYPPGITEYTLVKRLG" FT misc_feature 87819..88190 FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 30.00, E-value FT 5.4e-05" FT CDS complement(88263..89426) FT /transl_table=11 FT /gene="SCO3136" FT /gene_synonym="galK" FT /gene_synonym="SCE66.15c" FT /product="galactokinase" FT /note="SCE66.15c, galK, galactokinase (EC 2.7.1.6), len: FT 387aa; strongly similar to many eg. SW:P13227 (GAL1_STRLI) FT galactokinase from Streptomyces lividans (397 aa) fasta FT scores; opt: 2131, z-score: 2454.6, E(): 0, 88.8% identity FT in 383 aa overlap. Contains Pfam match to entry PF00288 FT GHMP_kinases, GHMP kinases putative ATP-binding proteins, FT Prosite match to PS00627 GHMP kinases putative ATP-binding FT domain and Prosite match to PS00106 Galactokinase FT signature." FT /db_xref="GOA:Q9K3S8" FT /db_xref="InterPro:IPR015870" FT /db_xref="UniProtKB/Swiss-Prot:Q9K3S8" FT /protein_id="CAB95929.1" FT /translation="MGEAVAGTVGERFRELYGAEPEGVWAAPGRVNLIGEHTDYNDGFV FT MPFALPHQAVAAVSRRDDGILRLHSADIDADPVELRVADLAPGSDKSWTAYPSGVLWAL FT REAGHELTGADVHLASTVPSGAGLSSSAALEVVLALAMNDLYALGLRGWQLARLCQRAE FT NVYVGAPVGIMDQTASACCEAGHALFLDTRDLSQRQIPFDLAAEGMRLLVVDTRVKHSH FT SEGEYGKRRAGCEKGAALLGVDALRDVPYADLDAALERLGDEEEVRRLVRHVVTEDERV FT ERVVALLESGDTRAIGAVLVEGHASLRDDFRISCPELDLVVDTALASGALGARMTGGGF FT GGSAIVLVEAAGVDAVTKAVEDAFAAAGLKAPRVFEAVPSAGARRLV" FT misc_feature complement(88923..89150) FT /note="Pfam match to entry PF00288 GHMP_kinases, GHMP FT kinases putative ATP-binding proteins, score 91.40, E-value FT 1.9e-24" FT misc_feature complement(89028..89063) FT /note="PS00627 GHMP kinases putative ATP-binding domain" FT misc_feature complement(89307..89342) FT /note="PS00106 Galactokinase signature" FT CDS complement(89462..90427) FT /transl_table=11 FT /gene="SCO3137" FT /gene_synonym="galE1" FT /gene_synonym="SCE66.16c" FT /product="UDP-glucose 4-epimerase" FT /note="SCE66.16c, galE1, UDP-glucose 4-epimerase (EC FT 5.1.3.2), len: 321aa; strongly similar to many eg. FT SW:P13226 (GALE_STRLI) UDP-glucose 4-epimerase from FT Streptomyces lividans (329 aa) fasta scores; opt: 1791, FT z-score: 2020.5, E(): 0, 89.4% identity in 321 aa overlap. FT Contains Pfam match to entry PF01370 Epimerase, NAD FT dependent epimerase/dehydratase family." FT /db_xref="GOA:Q9K3S7" FT /db_xref="HSSP:1GY8" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9K3S7" FT /protein_id="CAB95930.1" FT /translation="MSGKYLVTGGAGYVGSVVAQHLVEAGHEVVVLDNLSTGFREGVPA FT GASFVEGDIRDAAKWLDGSFDGVLHFAAFSQVGESVVKPEKYWDNNVGGTMALLEAMRG FT AGVRRLVFSSTAATYGEPEQVPIVESAPTRPTNPYGASKLAVDHMITGEAAAHGLGAVS FT LRYFNVAGAYGEYGERHDPESHLIPLVLQVAQGRREAISVYGDDYPTPDGTCVRDYIHV FT ADLAEAHLLAVAAAAPGEHLICNLGNGNGFSVREVVETVRRVTGHPIPEIMAPRRGGDP FT AVLVASAGTAREKLGWNPSRADLAGIVSDAWEFAQRRAGQ" FT misc_feature complement(89471..90415) FT /note="Pfam match to entry PF01370 Epimerase, NAD dependent FT epimerase/dehydratase family, score 458.40, E-value 6e-134" FT CDS complement(90424..91485) FT /transl_table=11 FT /gene="SCO3138" FT /gene_synonym="galT" FT /gene_synonym="SCE66.17c" FT /product="galactose-1-phosphate uridylyltransferase" FT /note="SCE66.17c, galT, galactose-1-phosphate FT uridylyltransferase (EC 2.7.7.10), len: 353aa; similar to FT many especially SW:P13212 (GAL7_STRLI) FT galactose-1-phosphate uridylyltransferase from Streptomyces FT lividans (354 aa) fasta scores; opt: 1998, z-score: 2363.0, FT E(): 0, 87.2% identity in 352 aa overlap. Contains Pfam FT match to entry PF01087 GalP_UDP_transf, FT Galactose-1-phosphate uridyl transferase and Prosite match FT to PS00117 Galactose-1-phosphate uridyl transferase family FT 1 active site signature." FT /db_xref="GOA:Q9K3S6" FT /db_xref="HSSP:1GUQ" FT /db_xref="InterPro:IPR019779" FT /db_xref="UniProtKB/TrEMBL:Q9K3S6" FT /protein_id="CAB95931.1" FT /translation="MKKTSTRLADGRELVYYDLRDDTVRDAVDRRPLERTVTTSEVRRD FT PLLGDSVAVASHRQGRTYHPPADQCPLCPSDGERLSEIPDSAYDVVVFENRFPSLAGDS FT GRCEVVCFTSDHDASFADLSEEQARLVLDAWTDRTSELSHLPSVEQVFCFENRGAEIGV FT TLGHPHGQIYAYPFTTPRTALMLRSLAAHKDATGGGNLFDSVLEEELAGERVVLEGEHW FT AAFVPYAAHWPYEVHLYPKRRVPDLLGLDEAARTEFPKVYLELLRRFDRIFGEGEPPTP FT YIAAWHQAPFGQLEEFEGVTRDDFALHLELFTIRRTSGKLKFLAGSESGMNVFINDVPP FT ERAAERLREVASS" FT RBS complement(90435..90440) FT misc_feature complement(90559..91482) FT /note="Pfam match to entry PF01087 GalP_UDP_transf, FT Galactose-1-phosphate uridyl transferase, score 451.80, FT E-value 5.7e-132" FT misc_feature complement(90973..91026) FT /note="PS00117 Galactose-1-phosphate uridyl transferase FT family 1 active site signature" FT RBS complement(91493..91497) FT CDS 91685..93373 FT /transl_table=11 FT /gene="SCO3139" FT /gene_synonym="SCE66.18" FT /product="putative sodium:solute symporter" FT /note="SCE66.18, possible sodium:solute symporter, len: FT 562aa; similar to many eg. SW:P96169 (SGLT_VIBPA) FT sodium/glucose co-transporter from Vibrio parahaemolyticus FT (543 aa) fasta scores; opt: 538, z-score: 594.1, E(): FT 1.3e-25, 27.8% identity in 479 aa overlap. Contains Pfam FT match to entry PF00474 SSF, Sodium:solute symporter family FT and possible membrane-spanning hydrophobic regions." FT /db_xref="GOA:Q9K3S5" FT /db_xref="InterPro:IPR019900" FT /db_xref="UniProtKB/TrEMBL:Q9K3S5" FT /protein_id="CAB95932.1" FT /translation="MQTPTSSTYLAAELRLPTNWLDYTILGIYFVVVLGIGFAARRSVR FT TSLDFFLSGRSLPAWVTGLAFVAANLGATEILGMAANSAQYGVYTTHWYWIGAIPAMVF FT LGLVMMPFYYGSKVRSVPEFLLLRFDKASHLLSSALFAIAAILIAGVNLYALAIVVEAL FT LGWPEWVAIVVAGFFVLAYITLGGLSSAIYNEVLQFFVILAGLIPITILGLKKVGGWDG FT LSDSLSKSHGSDFMTAWGGTGIGSENPLGANWLTIVLGLGFVLSFGYWTTNFAEVQRAL FT SAKNLSAAQRTPLIAAFPKIFIVFVVMIPGLVAAVLVPKIGTPGSDLQYNDAIPYLMQQ FT LLPNGVLGIAVTGLLAAFMAGMAANISSFNTVFTTDIWQKYVVKDREDGYYVRFGRLIT FT VIGVLASIGTAFLASSFSNIMSYLQTLFSFFNVPMFVVFIIGMFWKRASMKSGFWGLIA FT GTTAAMVNYFVIYKQGIIDIPSDQGANFVSAIAGFVAGAVVMVAVSLFTAPKPTADLQG FT LVYGTTSPGMAEAPAKGDDAWYRKPALLGWGAVVLAAACYIPFSF" FT misc_feature 91832..93061 FT /note="Pfam match to entry PF00474 SSF, Sodium:solute FT symporter family, score 90.00, E-value 4.9e-23" FT CDS 93395..93691 FT /transl_table=11 FT /gene="SCO3140" FT /gene_synonym="SCE66.19" FT /product="putative membrane protein" FT /note="SCE66.19, possible membrane protein, len: 98aa; FT contains possible membrane-spanning hydrophobic regions." FT /db_xref="UniProtKB/TrEMBL:Q9K3S4" FT /protein_id="CAB95933.1" FT /translation="MSDSYSDKNVQDEVSELETKSVTAARLFDIRRIIGGLFVIYGVIV FT TIAGFVASDEDIDKAQGVNINLWTGIGMLVLGLFFLAWLKLRPTAPPTPPREE" FT CDS <93721..93873 FT /transl_table=11 FT /gene="SCO3141" FT /gene_synonym="SCE66.20" FT /product="partial CDS, hypothetical" FT /note="SCE66.20, unknown, partial CDS, len: 50 aa; similar FT region of SC5F7.16 TR:Q9S2Q1 (EMBL:AL096872) hypothetical FT protein from Streptomyces coelicolor (140 aa) fasta scores; FT opt: 221, z-score: 268.2, E(): 1.9e-07, 69.6% identity in FT 46 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9K3S3" FT /protein_id="CAB95934.1" FT /translation="RCLTGTRGGRGLGRAPRRNGVPLRPPVPPQRHDCPQLGRSGDAAG FT EPRRR" FT CDS <93813..>93983 FT /transl_table=11 FT /gene="SCO3142" FT /gene_synonym="SCE66.21" FT /product="partial CDS, hypothetical" FT /note="SCE66.21, unknown, partial CDS, len: 57 aa; similar FT region of SC5F7.16 TR:Q9S2Q1 (EMBL:AL096872) hypothetical FT protein from Streptomyces coelicolor (140 aa) fasta scores; FT opt: 207, z-score: 278.8, E(): 4.8e-08, 69.4% identity in FT 49 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9K3S2" FT /protein_id="CAB95935.1" FT /translation="ARLPATGAERRRGGRAATAMSGRGAWAGRAAYGEEGACRGVSARS FT GWRVRAGEFCGR" FT stem_loop 93917..94029 FT /note="Score 57: 23/26 ( 88%) matches, 0 gaps, 40 base FT loop" FT CDS <93983..>94147 FT /transl_table=11 FT /gene="SCO3143" FT /gene_synonym="SCE66.22" FT /product="partial CDS, hypothetical" FT /note="SCE66.22, unknown, partial CDS, len: 55 aa; similar FT region of SC5F7.15 TR:Q9S2Q0 (EMBL:AL096872) hypothetical FT protein from Streptomyces coelicolor (234 aa) fasta scores; FT opt: 237, z-score: 237.2, E(): 9.9e-06, 59.0% identity in FT 61 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9K3S1" FT /protein_id="CAB95936.1" FT /translation="TDSAPFRGRTPPGAPPTHPPDKPRYPHPHHPAQAAAGTPAQPPEA FT PARSSNPVRA" FT CDS complement(94102..94776) FT /transl_table=11 FT /gene="SCO3144" FT /gene_synonym="SCE66.23" FT /product="putative two-component system response regulator" FT /note="SCE66.23, possible two-component system response FT regulator, len: 224aa; similar to many proposed regulators FT eg. TR:O53856 (EMBL:AL022004) putative response regulator FT from Mycobacterium tuberculosis (216 aa) fasta scores; opt: FT 352, z-score: 397.3, E(): 1.2e-14, 36.9% identity in 217 aa FT overlap. Contains Pfam match to entry PF00072 response_reg, FT Response regulator receiver domain and Pfam match to entry FT PF00196 GerE, Bacterial regulatory proteins, luxR family" FT /db_xref="GOA:Q9K3S0" FT /db_xref="HSSP:1FSE" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9K3S0" FT /protein_id="CAB95937.1" FT /translation="MGVRLMVVDDHRLLAEALASALKLRGHRVLAAAAPAAGAAELVIS FT RAPEVCLLGTATPAEPGNFDPVVRIKRERPQVAVLVLGPVPSPRGIAAAFASGASGYVR FT HDERIEGVERAIMKARAGEAAVAPALLQGAFGELLNPVAQPDDEGQRLLQLLTPREVEV FT LVRVADGEDTRLIAAGMGIAPSTARTHVQRVLMKLGVGSRLEAAALAARTGLLDRAGAS FT GG" FT misc_feature complement(94123..94320) FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 71.90, E-value FT 1.4e-17" FT misc_feature complement(94429..94770) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 8.20, E-value 0.00091" FT RBS complement(94784..94788) FT CDS complement(94996..96489) FT /transl_table=11 FT /gene="SCO3145" FT /gene_synonym="SCE66.24c" FT /product="putative secreted protein" FT /note="SCE66.24c, possible secreted protein, len: 497 aa; FT similar to TR:Q9K3R8 (EMBL:AL359989) Streptomyces FT coelicolor putative membrane protein SCE66.25c, 490 aa; FT fasta scores: opt: 430 Z-score: 424.1 E(): 5.4e-16; 33.012% FT identity in 518 aa overlap. Contains possible N-terminal FT signal sequence" FT /db_xref="InterPro:IPR011047" FT /db_xref="UniProtKB/TrEMBL:Q9K3R9" FT /protein_id="CAB95938.1" FT /translation="MPMQPQAAGGGRKINAQVAIIVSAVVAIALIIGGGVWYAGSSDGG FT GKDDTAGSSGGTGGDGGTDQKGGDGGKASGAEEKAPSDPASKVLFQVPMPAVTKEDDSV FT VVSGSWLTDKVYAKSGIAEVNGYDPAKGSKKWTIKLDGPVCAVTRHVTDDDKTVIIHQP FT AMPTKAEPSHGCTQVAVLDLDAGKKVWTKSAGEGPISFDNVTISGDTVAAGSSDGGVAF FT DIAKGDILWSPKAADSCYDAGYGGGEKLVAVRKCGSYDARQLNIQTIDPKSGKVITEYK FT MAKGIEYAGVVSTNPLVVAADVGDSAGDGSGISDFFSIDNKTGKLLTRISAPGDQFAAR FT CDSITKTESCNGLAAGNGKLYIATEEHESGGESYSRTNEVVAFDLTTGKQTGQRADSGE FT EYTITPLRMDGGNVIAYKRPPYDKGGQVVSIDGTTFKQTTLLENPATEAVRDVESSMSP FT DYSELIYSQGRLFMSQVYASEPTSADEKEYLAIGFGTSG" FT RBS complement(96824..96827) FT CDS complement(96910..98382) FT /transl_table=11 FT /gene="SCO3146" FT /gene_synonym="SCE66.25c" FT /product="putative secreted protein" FT /note="SCE66.25c, possible secreted protein, len: 490 aa; FT similar to TR:Q9K3R9 (EMBL:AL359989) Streptomyces FT coelicolor putative membrane protein SCE66.24c, 497 aa; FT fasta scores: opt: 430 Z-score: 454.0 E(): 1.2e-17; 33.140% FT identity) in 516 aa overlap. Contains possible N-terminal FT signal sequence" FT /db_xref="InterPro:IPR011047" FT /db_xref="UniProtKB/TrEMBL:Q9K3R8" FT /protein_id="CAB95939.1" FT /translation="MPPPGGPGSRNPFKGKPALAVGAAVAALLVIGGSVWAVTASGGDD FT EKDKKPVVAKTDDPKPSGSKGGAPVDPGDGSGDGGEDPEDLNEGRQAGESKVLWYKEAP FT DAPGSGADADGMWITGKAAVKAAYKQVFAYNVGDGKPAWEPIAFPEKICAVTPDKTADD FT KIVVAYMSGSSDRAKCNKLQEIDLATGQKGWSEEVADGDLFDSTLSLELSLSGNTMMVG FT RSQSGTAYDVKSGKKLYEKKKYGDACFPAGFAGSANKLVQVASCGAGGNNAHDELQGLD FT PKTGKVLWTYKYEKGWRIARAYSVDPLVVYATNEDKKVWNISSFTSGGKVQEQVGVDED FT FAPECGWAILERDLQGCTGVAVAAGTLYLPTEATSGANEIVAINLTTGKEKWRTKSPAD FT ESMMPLKIEGDQLIAYVQPSYDAGGQIVSIPTGGSSHQPAKLLQNPQGVADIENSFYSK FT DIDWVDGRFFISSTRLTGNDESKEKLMLAYGK" FT RBS complement(98725..98731) FT CDS complement(98975..100789) FT /transl_table=11 FT /gene="SCO3147" FT /gene_synonym="SCE66.26c" FT /product="putative ABC transporter ATP-binding subunit" FT /note="SCE66.26c, possible ABC transporter ATP-binding FT subunit, len: 604aa; similar to many others eg. TR:O06476 FT (EMBL:D86418) from Bacillus subtilis (629 aa) fasta scores; FT opt: 1223, z-score: 1292.7, E(): 0, 37.0% identity in 638 FT aa overlap. Contains two Pfam matches to entry PF00005 FT ABC_tran, ABC transporter, three Prosite matches to PS00017 FT ATP/GTP-binding site motif A (P-loop) and two Prosite FT matches to PS00211 ABC transporters family signature. Also FT contains possible coiled-coil region 544-604aa." FT /db_xref="GOA:Q9K3R7" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9K3R7" FT /protein_id="CAB95940.1" FT /translation="MAVNLVNVENVSKVYGTRALLDGVSLGVSEGDRIGVVGRNGDGKT FT TMIRMLARLEEPDTGRVTHSGGLRLGVLTQHDSLDPEATVRHEVIGDMADHEWAGNAKV FT RDVLTGLFGGLDMPGFPQGLDTVIGPLSGGERRRIALAKLLIEEQDLVVLDEPTNHLDV FT EGIAWLAGHLRERRSALVCVTHDRWFLDQVCTRMWDVQKGDVYEYEGGYSDYVFARAER FT ERIAATEETKRQNLVRKELAWLRRGAPARTSKPRFRVEAANELIADVPPPRDSSELMKF FT ASSRLGKTVFDLEDVTVQAGPKVLLKHVTWQLGPGDRIGLVGVNGAGKTSLLRAMAEAA FT RSEGERQPAGGQVKVGRTVKLAYLSQEVAELDPNWRVLEAVQRVRERVDLGKGREMTAG FT QLCETFGFGKEKQWTPVGDLSGGERRRLQLLRLLMDEPNVLFLDEPTNDLDIETLTQLE FT DVLDGWPGSMIVISHDRFFVERTTDRVFALLGDGALRMLPRGIDEYLERRRRMEEAAAS FT SAPAVAAKPAAAVPEKSAADVRAAKKELQKIERQLDKVSEKETKLHAQIAENATDFAKV FT AELDAELRELTGQRDELELRWLELAEDA" FT misc_feature complement(99317..99844) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 117.20, E-value 3e-31" FT misc_feature complement(99491..99535) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(99800..99823) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(99923..99946) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(100181..100699) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 124.40, E-value 2.2e-33" FT misc_feature complement(100355..100399) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(100655..100678) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(100794..100798) FT CDS complement(100847..101746) FT /transl_table=11 FT /gene="SCO3148" FT /gene_synonym="SCE66.27c" FT /product="putative isopentenyl monophosphate kinase" FT /note="SCE66.27c, possible isopentenyl monophosphate FT kinase, len: 299 aa; similar to many e.g. SW:O05596 FT (IPK_MYCTU) isopentenyl monophosphate kinase from FT Mycobacterium tuberculosis (306 aa) fasta scores; opt: 925, FT z-score: 1022.2, E(): 0, 54.5% identity in 297 aa overlap FT and SW:P56848 (IPK_MENPI) isopentenyl monophosphate kinase FT from Mentha piperita (Peppermint) (405 aa) fasta scores; FT opt: 395, z-score: 439.8, E(): 5.1e-17, 33.6% identity in FT 265 aa overlap." FT /db_xref="GOA:Q9K3R6" FT /db_xref="InterPro:IPR014721" FT /db_xref="UniProtKB/Swiss-Prot:Q9K3R6" FT /protein_id="CAB95941.1" FT /translation="MSVTVRVPAKVNVQLAVGAARPDGFHDLANVFLAVSLYDEVTATP FT AADGLRVTCEGPDAGQVPLDRTNLAARAAEALAARYGRAPDVHLHIAKDIPVAGGMAGG FT SADGAGALLACDALWGTGASREELLEICAGLGSDVPFSLVGGAALGTGRGERLAELEVG FT GDFHWVFALAARGLSTPAVFREFDRLGEGLDLPEPVADQAVLDALAKGDAAALAVAVTN FT DLQPAALSLFPELSDTLAAGRAAGALAALVSGSGPTTAFLATDARSASDIAGVLRASGT FT CRDVRTAVGAAAGATVLD" FT RBS complement(101757..101760) FT CDS complement(101761..102621) FT /transl_table=11 FT /gene="SCO3149" FT /gene_synonym="SCE66.28c" FT /product="putative dimethyladenosine transferase" FT /note="SCE66.28c, possible dimethyladenosine transferase, FT len: 286aa; similar to many eg. SW:P06992 (KSGA_ECOLI) FT dimethyladenosine transferase from Escherichia coli (273 FT aa) fasta scores; opt: 425, z-score: 481.5, E(): 2.4e-19, FT 32.8% identity in 262 aa overlap. Contains Pfam match to FT entry PF00398 RrnaAD, Ribosomal RNA adenine dimethylases FT and Prosite match to PS01131 Ribosomal RNA adenine FT dimethylases signature." FT /db_xref="GOA:Q9K3R5" FT /db_xref="InterPro:IPR011530" FT /db_xref="UniProtKB/Swiss-Prot:Q9K3R5" FT /protein_id="CAB95942.1" FT /translation="MSSPTPDALLGPADVRELAAALGVRPTKQRGQNFVIDANTVRRIV FT RTAEVRPDDVVVEVGPGLGSLTLALLEAADRVTAVEIDDVLAGALPATVAARMPARADR FT FALVHSDAMHVRELPGPAPTALVANLPYNVAVPVLLHMLDTFPGIERTLVMVQAEVADR FT LAAGPGSKVYGVPSVKANWYAEVKRAGSIGRNVFWPAPNVDSGLVSLVRRSEPLRTTAS FT KAEVFAVVDAAFAQRRKTLRAALAGWAGSAAAAEAALVGAGVSPQARGEALTVEEFARI FT AEHKV" FT misc_feature complement(101773..102528) FT /note="Pfam match to entry PF00398 RrnaAD, Ribosomal RNA FT adenine dimethylases, score 164.00, E-value 3e-50" FT misc_feature complement(102373..102456) FT /note="PS01131 Ribosomal RNA adenine dimethylases FT signature" FT CDS complement(102652..104028) FT /transl_table=11 FT /gene="SCO3150" FT /gene_synonym="SCE87.01c" FT /gene_synonym="SCE66.29c" FT /product="hypothetical protein" FT /note="SCE87.01c, unknown, partial CDS, len: > 329 aa. FT Similar in parts to Mycobacterium tuberculosis TR:O05594 FT (EMBL:Z94752) hypothetical 38.1 KD protein (362 aa), fasta FT scores opt: 365 z-score: 372.3 E(): 2.3e-13 34.1% identity FT in 232 aa overlap and Bacillus subtilis SW:YABE_BACSU FT (EMBL:D26185) hypothetical 47.7 KD protein (437 aa), fasta FT scores opt: 315 z-score: 321.5 E(): 1.5e-10 29.2% identity FT in 233 aa overlap." FT /note="SCE66.29c, unknown, partial CDS, len: >165aa; FT similar to TR:O05594 (EMBL:Z94752) hypothetical protein FT from Mycobacterium tuberculosis (362 aa) fasta scores; opt: FT 316, z-score: 379.7, E(): 1.1e-13, 37.8% identity in 156 aa FT overlap." FT /db_xref="GOA:Q8CJX5" FT /db_xref="InterPro:IPR010618" FT /db_xref="UniProtKB/TrEMBL:Q8CJX5" FT /protein_id="CAD55494.1" FT /translation="MSRTQFEPAETYTAYTAYDEAYEAHEAYEAHEAYEAHETYERPAP FT YDLHSAPTLPYGGTYPSAPPPVHEPTVPALPRQSDGRAERRRRARGAGRADASLRRLVP FT RALVVAFLAGGTTAFVAKDKAVELTVDGSPRTLHTFADDVSELLAEEGVQVGAHDVIAP FT APGTPLTSGEDVTVHHGRPVLLTLDGHRRQVWTTAGTVAGALRQLGVRTQGAYLSTGPS FT RRIGREGLALVVRTERVVTVMADGRTRTVRTNAATVGEVVEEAGITLRGEDTTSVPATG FT FPRDGQTVTVLRITGSQEVREDPIPFDERRAEDASLFRGTEVVQEAGRPGLRRTTYALR FT TVNGVRQKPRRLRTEVVREPSPRIVRVGTRPRPASVHGADHLNWQGLAACESGGRADAV FT DPSGTYGGLYQFDSATWHGLGGEGRPEDASAAEQTYRAQKLYVRSGADAWPHCGARLRE FT " FT RBS complement(104038..104041) FT CDS complement(104116..105006) FT /transl_table=11 FT /gene="SCO3151" FT /gene_synonym="SCE87.02c" FT /product="conserved hypothetical protein SCE87.02c" FT /note="SCE87.02c, unknown, len: 296 aa. Highly similar to FT many hypothetical proteins including: Mycobacterium FT tuberculosis TR:O08343 (EMBL: Z94752) hypothetical protein FT YcfH (264 aa), fasta scores opt: 576 z-score: 667.6 E(): FT 8.2e-30 42.7% identity in 279 aa overlap and Escherichia FT coli SW:YCFH_ECOLI (EMBL:AE000210) hypothetical 29.8 KD FT protein (265 aa), fasta scores opt: 477 z-score: 554.2 E(): FT 1.7e-23 37.0% identity in 276 aa overlap. Contains a Pfam FT match to entry PF01026 UPF0006, Uncharacterized protein FT family" FT /db_xref="GOA:Q9RKD6" FT /db_xref="HSSP:1J6O" FT /db_xref="InterPro:IPR015992" FT /db_xref="UniProtKB/TrEMBL:Q9RKD6" FT /protein_id="CAB59647.1" FT /translation="MPSNASGRSDKDGAPPLPEPLRVPVADSHTHLDMQSGTVEEALAK FT AASVGVTTVVQVGCDLAGSRWAAETAAAHDAVHATVALHPNEAPRIVHGDPDGWSRQGA FT REPGGDAALDDALAEIDRLAALPQVKGVGETGLDYFRTGPEGKEAQERSFRAHIEIAKR FT HGKTLVIHDRDAHTDVLRVLKEEGAPERTVFHCYSGDAEMAGICARAGYYMSFAGNVTF FT KNAQNLRDALAVAPPELVLVETDAPFLTPAPYRGRPNAPYLVPVTVRAMAEVRGVDEDT FT LATALAANTARAFGY" FT misc_feature complement(104122..104919) FT /note="Pfam match to entry PF01026 UPF0006, Uncharacterized FT protein family, score 241.70, E-value 1e-68" FT RBS complement(105014..105017) FT CDS complement(105047..105484) FT /transl_table=11 FT /gene="SCO3152" FT /gene_synonym="SCE87.03c" FT /product="hypothetical protein SCE87.03c" FT /note="SCE87.03c, unknown, len: 145 aa." FT /db_xref="UniProtKB/TrEMBL:Q9RKD5" FT /protein_id="CAB59648.1" FT /translation="MSMSESAVRTGVRAGATAVVHESYSFACMRCGHGWEQSFEIEHHT FT DTDGREFVLYVADGRVVPSPLTRPTCATCDSHVVRILRPGRVASVRGAAHTVHRVPPAG FT PLEVPLVPEAPGPGAPGLSGGRRHWHLADLLHAFHLHRGAS" FT RBS complement(105490..105495) FT CDS complement(105641..106501) FT /transl_table=11 FT /gene="SCO3153" FT /gene_synonym="SCE87.04c" FT /product="conserved hypothetical protein" FT /note="SCE87.04c, conserved hypothetical protein, len: 286 FT aa. Highly similar to many including: Mycobacterium FT tuberculosis SW:YA03_MYCTU (EMBL:Z94752) hypothetical 29.7 FT KD protein RV1003 (285 aa), fasta scores opt: 877 z-score: FT 992.7 E():0 53.6% identity in 278 aa overlap and Bacillus FT subtilis SW:YABC_BACSU (EMBL:D26185) hypothetical 33.0 KD FT protein (292 aa), fasta scores opt: 640 z-score: 726.6 FT E():0 41.3% identity in 276 aa overlap. Contains a Pfam FT match to entry PF00590 TP_methylase, Tetrapyrrole FT (Corrin/Porphyrin) Methylases." FT /db_xref="GOA:Q9RKD4" FT /db_xref="InterPro:IPR008189" FT /db_xref="UniProtKB/TrEMBL:Q9RKD4" FT /protein_id="CAB59649.1" FT /translation="MTGTLVLAGTPIGDVQDAPPRLAAELAGADVVAAEDTRRLRRLTQ FT ALGVAPAGRVVSYFEGNESARTPELVEELAGGARVLLVTDAGMPSVSDPGYRLVAAAVE FT RGVRVTAVPGPSAVLTALALSGLPVDRFCFEGFLPRKAGERLTRLREVAGERRTLVYFE FT APHRLDDTLAAMAEVFGTDRRAAVCRELTKTYEEVRRGGLGELAAWAGEGVRGEITVVV FT EGAPDKGPEEVGAEELVRRVRVREEAGERRKEAIAAVAAEVGVPKREVFDAVVAAKNAE FT KNTGI" FT misc_feature complement(105881..106492) FT /note="Pfam match to entry PF00590 TP_methylase, FT Tetrapyrrole (Corrin/Porphyrin) Methylases., score 133.00, FT E-value 5.5e-36" FT RBS complement(106510..106514) FT RBS 106549..106553 FT CDS 106568..108343 FT /transl_table=11 FT /gene="SCO3154" FT /gene_synonym="SCE87.05" FT /product="putative integral membrane protein." FT /note="SCE87.05, possible integral membrane protein, len: FT 591 aa. Similar to several of undefined function e.g. FT Mycobacterium tuberculosis TR: O05586 (EMBL: Z94752) FT hypothetical 55.5 KD protein (503 aa), fasta scores opt: FT 666 z-score: 775.7 E(): 0 39.0% identity in 544 aa overlap FT and Aeropyrum pernix TR:BAA79111 (EMBL:AP000058) 418aa FT long hypothetical protein (418 aa), fasta scores opt: 201 FT z-score: 235.2 E(): 9.9e-06 30.4% identity in 299 aa FT overlap. Contains multiple possible membrane spanning FT hydrophobic domains." FT /db_xref="GOA:Q9RKD3" FT /db_xref="InterPro:IPR003342" FT /db_xref="UniProtKB/TrEMBL:Q9RKD3" FT /protein_id="CAB59650.1" FT /translation="MHSAVPYDGAVTSTASSTDTLHDQAPHDERPTWQQRLRRFGYPAG FT PATGDVRDRLVPPYTSPSPRLWAFLGVSKPLTDRMIRWSAWGGPLLVALFAGVLRFWNL FT GSPKAVIFDETYYAKDAWALIHRGFEVNWDKNANDLILNSGGDVPIPTDAAYVVHPPVG FT KYIIGLGELLFGFDPFGWRFMTALLGTLSVLLLCRIGRRLFRSTFLGCLAGALMALDGL FT HFVMSRTALLDSVLMFFVLAAFGCLVVDRDKARSRLAAALPVDEDGRVRPDAHVAETLR FT LGWRPWRLAAGLMLGLAAATKWNGLYIMAAFCVMAVLWDVGSRRVAGAHRPYRAVLRHD FT LGWAFLSTVPVALATYLLSWLGWILSPSDGTGGYYRDWATKDGANSSWSWLFPDWWRSL FT WHYETQVLEFHTHLTSPHTYQSNPWSWIVLGRPVSYFYESPSAGSDGCPVDAGEKCARE FT VLALGTPLLWWVGCFALLYVLWRWLFRRDWRAGAIACGVAAGYLPWFMYQERTIFLFYA FT VVFLPFLCLAVAMLLGAIIGRPGCTDTRRVAGATGAGVLVLLIAWNFIYFWPLYTGTAI FT PMEEWRARMWLDTWV" FT CDS 108397..108936 FT /transl_table=11 FT /gene="SCO3155" FT /gene_synonym="SCE87.06" FT /product="hypothetical protein SCE87.06" FT /note="SCE87.06, unknown, len: 179 aa." FT /db_xref="UniProtKB/TrEMBL:Q9RKD2" FT /protein_id="CAB59651.1" FT /translation="MTRMVEDGTSLGPLELAGGRWGVGDASRPGTYWVEFRPDGLYQHE FT PDSGGRLIPWSRVMTGVWLTWGKHAWNTNNRGKYTLKGMVAERTGGWMHLTLRHPYEDT FT QLRFDQHERPYRAVDALRLEHLLRQLIDEEKLQLLGDPEWVGRAVAHLAGGKNSWLTDR FT ALRRVAKEAVATATGH" FT RBS 109153..109157 FT CDS 109167..110792 FT /transl_table=11 FT /gene="SCO3156" FT /gene_synonym="SCE87.07" FT /product="putative penicillin-binding protein (putative FT secreted protein)" FT /note="SCE87.07, possible penicillin-binding protein FT (putative secreted protein), len: 541 aa. Similar to many FT including: Bacillus subtilis SW:PBPB_BACSU (EMBL:L09703) FT penicillin-binding protein 2B (PBP-2B) (716 aa), fasta FT scores opt: 221 z-score: 233.6 E(): 1.2e-05 26.8% identity FT in 336 aa overlap and Streptomyces coelicolor TR: CAB45623 FT (EMBL:AL079356) putative penicillin-binding protein FT SC6G9.32 (485 aa), fasta scores opt: 241 z-score: 257.0 FT E(): 6.1e-07 28.9% identity in 464 aa overlap. Also similar FT to the neighbouring CDS SCE87.08 (591 aa), fasta scores FT opt: 653 z-score: 627.3 E(): 1.3e-29 45.1% identity in 550 FT aa overlap. Contains a Pfam match to entry PF00905 FT Transpeptidase, Penicillin binding protein transpeptidase FT domain and a possible N-terminal signal sequence." FT /db_xref="GOA:Q9RKD1" FT /db_xref="HSSP:1K25" FT /db_xref="InterPro:IPR001460" FT /db_xref="UniProtKB/TrEMBL:Q9RKD1" FT /protein_id="CAB59652.1" FT /translation="MGRGVKVAVIGGVFAVMVGGAGYGAYNVVSALDEGGGSGSSEAKS FT GPPDKDEVAETSEKFFAAWEKGDATTAASYTNNASIAGTLLTAYGEDAHIGGVEITPGT FT AAGTSVPFTVKAKVSYEGTTKPLSYRSTLTVVRGETSGRALVDWKPSVVHPDLKDGDTL FT VTTESATPQIQAVGRDGTVLTKEKYPSLGPVLATLRERYGAQAGGTPGVELAVRHTVAS FT TPDTPLLTLTEGKPGKLETTLSASVQAAAEKAVKRYGESSVVAVKPSTGEVLAVANNRQ FT DGFNAAFQGKVAPGSTMKILTAAMLIDNGVTSMNGPAPCPETATWQSQTFHNITTMKPN FT MSATLANTFMRSCNTGFIKLVDEKPLTDSSLTQEAQERFGLGQDNWQTGIVSFDGSVPA FT SGGPDRAANAIGQGQVQMNPLNMASVTATAITGEFRQPYLVPFDLDDREPATAKGLPQG FT TASQLKQMMRLTATQGTAVNAMSGLSGDIGAKTGSAEVDGQAVSNAWFTGFRNDVAAAA FT MTEEGGHGGDAAGPIVADVLRVGG" FT misc_feature 109899..110783 FT /note="Pfam match to entry PF00905 Transpeptidase, FT Penicillin binding protein transpeptidase domain, score FT 123.40, E-value 4.2e-33" FT RBS 110863..110866 FT CDS 110877..112652 FT /transl_table=11 FT /gene="SCO3157" FT /gene_synonym="SCE87.08" FT /product="putative penicillin-binding protein (putative FT secreted protein)" FT /note="SCE87.08, possible penicillin-binding protein FT (putative secreted protein), len: 591 aa. Similar to many FT including: Streptomyces clavuligerus TR:P72405 FT (EMBL:U56256) penicillin-binding protein PcbR (551 aa), FT fasta scores opt: 775 z-score: 731.0 E(): 0 36.5% identity FT in 526 aa overlap and Streptomyces coelicolor TR:CAB45214 FT (EMBL:AL079308) putative penicillin-binding protein FT SCH69.17 (490 aa), fasta scores opt: 234 z-score: 226.4 FT E(): 3.1e-05 26.2% identity in 416 aa overlap. Also similar FT to the neighbouring CDS SCE87.07 (541 aa), fasta scores FT opt: 653 z-score: 513.9 E(): 2.7e-23 45.1% identity in 550 FT aa overlap. Contains a Pfam match to entry PF00905 FT Transpeptidase, Penicillin binding protein transpeptidase FT domain and a possible N-terminal signal sequence." FT /db_xref="GOA:Q9RKD0" FT /db_xref="InterPro:IPR001460" FT /db_xref="UniProtKB/TrEMBL:Q9RKD0" FT /protein_id="CAB59653.1" FT /translation="MGSRRGAATGRRRTKPAVIGSVAAVVVAGAGFGAYAMYGGGETGD FT DNARTKSAAAAEKVKSGPLTAAEVTSTAQRFLTAWQRGDVAGAAAATDDAEAAKALLTG FT YAKDARIKDATFTAGAPAGEKVPFSVKATVAYEKAAEPLAYDSALTVVRREGDGEPRVD FT WHAAVVHPELRDGDRLVTGKAGDPPVKALDRNGAEITAAKYPSLGTVLDGLRDKYGKKS FT GGTPGVELRVVRGKSTGDGKGSQESGAGEVADKTLLELSKGTPGTLKTTLDPALQTAAE FT KQVDGKKGASVVLLRASTGEVLAVANGGHGFNTAFLGSLAPGSTMKVITASMLLEKDLA FT SVNEKHPCPKYFSYGGWKFQNDDEFEIKDGTFKASFARSCNTAFISQAPELKDDDLTRQ FT AKEVFGLSMNNWSVGVSTFDGRVPVQSKAQMAASLIGQGGVRMNPLNMASVSATVKSGS FT FHQPYLVAPSVDGRALATASRTMSGETLGALRELMSYTAAYGTAAEAMAGVGGDVGAKT FT GSAEVDRAGEAQRLVHGLPGGPGGGGRGPAGRARRRHRGPDRRGAAQGRRLTPGARLSG FT PPAARSPRRCGAGSG" FT misc_feature 111696..112526 FT /note="Pfam match to entry PF00905 Transpeptidase, FT Penicillin binding protein transpeptidase domain, score FT 58.20, E-value 1.8e-13" FT CDS complement(112597..112977) FT /transl_table=11 FT /gene="SCO3158" FT /gene_synonym="SCE87.09c" FT /product="hypothetical protein SCE87.09c" FT /note="SCE87.09c, unknown, len: 126 aa. Similar to two FT putative regulators from Streptomyces coelicolor: FT TR:CAB51005 (EMBL:AL096852) SCE19A.24 (142 aa), fasta FT scores opt: 168 z-score: 227.4 E(): 2.7e-05 32.7% FT identity in 101 aa overlap and TR:CAB40672 (EMBL: FT AL049587) SC5F2A.05C (138 aa), fasta scores opt: 222 FT z-score: 296.3 E(): 3.9e-09 36.0% identity in 114 aa FT overlap." FT /db_xref="InterPro:IPR006776" FT /db_xref="UniProtKB/TrEMBL:Q9RKC9" FT /protein_id="CAB59654.1" FT /translation="MSVVEQYARAHILTDGDLPDQDDGGAIPVVLRYDPQLDPSKVCVA FT LPGRGGRASGSREWTFSRELLEQGLRAPAGSGEVRVWPCGRVQAVVEFHSPQGCSVVQF FT ENKALIRFLRRTYAATAQPVAH" FT CDS 113163..114224 FT /transl_table=11 FT /gene="SCO3159" FT /gene_synonym="SCE87.10" FT /product="putative membrane protein" FT /note="SCE87.10, possible membrane protein, len: 353 aa. FT Weakly similar to Salmonella typhimurium SW:CBIM_SALTY FT (EMBL:L12006) cobalamin biosynthesis protein CbiM (245 aa), FT fasta scores opt: 224 z-score: 251.7 E(): 1.2e-06 32.8% FT identity in 180 aa overlap. Also similar to FT Methanobacterium thermoautotrophicum TR: O27742 FT (EMBL:AE000928) cobalamin biosynthesis protein M (217 aa), FT fasta scores opt: 495 z-score: 544.6 E(): 5.9e-23 41.4% FT identity in 220 aa overlap. Contains multiple possible FT membrane spanning hydrophobic domains and a possible FT N-terminal signal sequence" FT /db_xref="GOA:Q9RKC8" FT /db_xref="InterPro:IPR002751" FT /db_xref="UniProtKB/TrEMBL:Q9RKC8" FT /protein_id="CAB59655.1" FT /translation="MHVPDGFINAPTSAVTGVVAAGAIAVSLRGARRELDERTAPLAGL FT VAAFIFAVQMLNFPVAAGTSGHLLGGALAAILVGPCTGVLCVSVVLLMQGILFADGGLT FT ALGVNITDMAIVTTVVAYALFRGLVKVLPRTRRSVTVASFVAALVSVPAAALAFTLLYW FT IGGTTDVSIGKVATAMIGVHLLIGIGEAAITALTVGAVIAVRPDLVYGARGLQQRLKLR FT VNGELVDAPGAGPAPVPAPVAARSHRKVWITGLVASLVLAGFVSFYASADPDGLEKVAS FT DKGIDEKAKEHANADSPLADYGVEDITNARVSGGLAGVIGVGVTVVAGSAVFWAVRRRR FT SEDASPTSTETTV" FT CDS 114226..114987 FT /transl_table=11 FT /gene="SCO3160" FT /gene_synonym="SCE87.11" FT /product="putative integral membrane transport protein" FT /note="SCE87.11, possible integral membrane transport FT protein, len: 253 aa. Similar to many proteins thought to FT be involved in the transport of cobalt e.g. Streptomyces FT coelicolor TR:O54188(EMBL:AL021411) cobalt transport FT integral membrane protein SC7H1.29c (CbiQ) (249 aa), fasta FT scores opt: 196 z-score: 249.6 E(): 1.6e-06 25.5% identity FT in 251 aa overlap and Methanobacterium thermoautotrophicum FT TR:O27740(EMBL:AE000928) cobalt transport membrane protein FT (261 aa), fasta scores opt: 332 z-score: 417.0 E(): 7.5e-16 FT 30.2% identity in 212 aa overlap. Contains multiple FT possible membrane spanning hydrophobic domains." FT /db_xref="GOA:Q9RKC7" FT /db_xref="InterPro:IPR012809" FT /db_xref="UniProtKB/TrEMBL:Q9RKC7" FT /protein_id="CAB59656.1" FT /translation="MGAGHAHRLYRHGHSPVHGLPPHTKLAAVFAFVVVVVSTPREAMW FT AFGLYALLLATVACAARVPAAFLLKRLLIEVPFVAFAVLMPFVAQGERVEVLGLSLSVN FT GLWGAWNVLAKGTLGVAASVLLASTTELRELLLGLQRLRLPPLLVQIASFMIRYGDVIA FT DEMRRMRIARESRGFEAKGVRHWGVLAKSAGALFIRSYERGERVHLAMVSRGYAGSMPV FT IDEVTASRAQWSYALALPCAALVVCLLGWTL" FT CDS 114996..115778 FT /transl_table=11 FT /gene="SCO3161" FT /gene_synonym="SCE87.12" FT /product="putative ABC transport protein, ATP-binding FT subunit." FT /note="SCE87.12, possible ABC transport protein, FT ATP-binding subunit, len: 260 aa. Highly similar to many FT cbiO-like proteins thought to be involved in ATP-dependent FT cobalt transport e.g. Methanococcus jannaschii FT TR:Q58488(EMBL:U67551) cobalt transport ATP-binding protein FT (279 aa), fasta scores opt: 737 z-score: 823.3 E(): 0 45.8% FT identity in 238 aa overlap and Streptomyces coelicolor FT TR:O54187 (EMBL:AL021411) cobalt transport system ATP FT binding protein SC7H1.28c (284 aa), fasta scores opt: 664 FT z-score: 742.6 E():0 44.4% identity in 261 aa overlap. FT Contains a possible membrane spanning hydrophobic domain FT and a Pfam match to entry PF00005 ABC_tran, ABC FT transporter. Also contains Prosite hits to PS00211 ABC FT transporters family signature and PS00017 ATP/GTP-binding FT site motif A (P-loop)." FT /db_xref="GOA:Q9RKC6" FT /db_xref="HSSP:1F2U" FT /db_xref="InterPro:IPR005876" FT /db_xref="UniProtKB/Swiss-Prot:Q9RKC6" FT /protein_id="CAB59657.1" FT /translation="MTGPAAAPVPDAPASLDVSGLAFAYPDGHQALFGVDFCVARGERV FT ALLGPNGAGKTTLVLHLNGILTGGTGTVTVAGLPVDKRNMAEIRRRVGIVFQDPDDQLF FT MPTVREDVAFGPAAAGVKGAELEACVDRALTLVGMAEFKDRPPHHLSFGQRRRVAVATV FT LAMEPEILVLDEPSSNLDPASRRELADILRSLDVTVLMVTHDLPYALELCPRALILSDG FT AIAADGPTAALLSDDDLMRAHRLELPFGFDPRSVRASG" FT misc_feature 115119..115661 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 191.50, E-value 1.4e-53" FT misc_feature 115140..115163 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 115443..115487 FT /note="PS00211 ABC transporters family signature" FT RBS 115777..115780 FT CDS 115796..117058 FT /transl_table=11 FT /gene="SCO3162" FT /gene_synonym="SCE87.13" FT /product="putative esterase" FT /note="SCE87.13, possible esterase, len: 420 aa. Similar to FT several including: Streptomyces chrysomallus FT TR:O87861(EMBL:Z15137) esterase A (389 aa), fasta scores FT opt: 684 z-score: 729.1 E():0 44.9% identity in 405 aa FT overlap and Pseudomonas fluorescens TR:Q53403 (EMBL:S69066) FT esterase III (382 aa), fasta scores opt: 597 z-score: FT 637.2 E(): 4e-28 41.8% identity in 397 aa overlap." FT /db_xref="InterPro:IPR001466" FT /db_xref="UniProtKB/TrEMBL:Q9RKC5" FT /protein_id="CAB59658.1" FT /translation="MAVASTVTGDRKGRTEVGVNVHGTVAEGFEPVRDAFARNFTSLGE FT RGAAVAVYRDGRKVVDLWGGSRDVDDASGTEPWRRGTAQVVRSATKGVAAAVPLLLHRR FT GELDLDAPVGEYWPEFKAHGKERVLVRHVLNHRAGLPVLDRPLTPEEALDPRRGPAAVA FT AQAPVWEPGTDHGYHALTYGWLLDELVRRVSGGRGAGQWIADEIAGPLGLDLWVGLPAA FT EEAAGRAGRVGRLDEPEPSGSGNGPRLRPKRAVTEAYENPGSLTRRAFAAITPFPDQND FT PEYRAAALPAANGIATADGLARFYAALIGEVDGVTRDVRLFDRATMELARAEESAGPDR FT ILVVGTRFGLGYMLHGSASPFLGPGSFGHPGRGGSLGFADPETGIALGYVTNGFRKTVT FT ADPRAQALVRAVRASLDRDPS" FT CDS complement(117117..117392) FT /transl_table=11 FT /gene="SCO3163" FT /gene_synonym="SCE87.14c" FT /product="hypothetical protein SCE87.14c" FT /note="SCE87.14c, unknown, len: 91 aa. Similar to a FT hypothetical protein from Mycobacterium tuberculosis: FT SW:YQ32_MYCTU (EMBL:Z80225) hypothetical 10.1 KD protein FT (93 aa), fasta scores opt: 112 z-score: 161.8 E(): 0.12 FT 31.3% identity in 83 aa overlap." FT /db_xref="InterPro:IPR015057" FT /db_xref="UniProtKB/TrEMBL:Q9RKC4" FT /protein_id="CAB59659.1" FT /translation="MMHTTVGWHVELEFTEDDQHTRAVAMVRLPDGTEVRAHGHASRHR FT VDSRQPRVGEEVAGARALNELAMQLLTKAHDEIDAASGRTSHPIHV" FT RBS complement(117396..117405) FT CDS complement(117482..118327) FT /transl_table=11 FT /gene="SCO3164" FT /gene_synonym="SCE87.15c" FT /product="putative integral membrane protein" FT /note="SCE87.15c, possible integral membrane protein, len: FT 281 aa. Weakly similar to Bacillus subtilis SW:YWFM_BACSU FT (EMBL:X73124) hypothetical 31.3 KD protein in PTA 3'region FT (296 aa), fasta scores opt: 157 z-score: 184.7 E(): 0.0065 FT 22.9% identity in 279 aa overlap. Contains multiple FT possible membrane spanning hydrophobic domains and a FT possible N-terminal signal sequence. Also similar to FT TR:CAC45825 (EMBL:AL591786) Rhizobium meliloti FT (Sinorhizobium meliloti) hypothetical transmembrane protein FT SMC01807, 278 aa; fasta scores: opt: 605 Z-score: 660.4 FT E(): 3.7e-29; 38.811% identity in 286 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9RKC3" FT /protein_id="CAB59660.1" FT /translation="MTPLVTAAVLLAAVTHASWNAIAHRITDKLTGFALISGGGMLIGL FT ALLPFTAFPAAGAWPYLLVSAAIHIAYYALLMRSFRLGDFGQAYPIARGSAPLLVTVLA FT AVFAHEVPDGWATGGVLVSCAGLTGVALWGLRGRRPDWAAIGAALATGVTIAAYTVVDG FT LGVRASGSSLGYIAWLMAVQGTVLPACFLYRHRAGAWALLRPQAGLGLVGAALSVTAYA FT LVLWAQTRAELAPIAALRESSILVGAAIGALFFKERFGAPRIAAAGLLVVGIGLMLHTG FT " FT CDS complement(118324..118863) FT /transl_table=11 FT /gene="SCO3165" FT /gene_synonym="SCE87.16c" FT /product="hypothetical protein SCE87.16c" FT /note="SCE87.16c, unknown, len: 179 aa. Weakly similar to FT several including: Aeropyrum pernix TR:BAA81557 (EMBL: FT AP000064) 152 aa long hypothetical protein (152 aa), fasta FT scores opt: 249 z-score: 300.9 E(): 2.2e-09 38.9% FT identity in 131 aa overlap and Streptomyces coelicolor FT TR:CAB51450 (EMBL:AL096884) putative transcriptional FT regulatory protein SC4G6.27 (169 aa), fasta scores opt: 198 FT z-score: 241.6 E(): 4.4e-06 27.9% identity in 129 aa FT overlap." FT /db_xref="InterPro:IPR007214" FT /db_xref="UniProtKB/TrEMBL:Q9RKC2" FT /protein_id="CAB59661.1" FT /translation="MTTTDDASGPAATSGSAGASAAHPRFAAALGELGLGDLAGRARRF FT PEATRTAAEAAAAIGCELSQICKSLIFAADGVPVLVLMDGASRVDLDRVRDALGAGKVT FT RAKADVVRETTGYAIGGVPPFGHRTRTRVLADRSLLAHDVVWAAAGTPYAVFPMEPEDL FT VATAGATLVDVRERSE" FT CDS complement(119022..121259) FT /transl_table=11 FT /gene="SCO3166" FT /gene_synonym="SCE87.17c" FT /product="putative membrane transport protein" FT /note="SCE87.17c, possible membrane transport protein, len: FT 745 aa. Highly similar to several other Streptomyces FT coelicolor putative transport proteins: TR:CAB56653 FT (EMBL:AL121596) putative membrane transport protein FT SCF51A.01C (765 aa), fasta scores opt: 1664 z-score: 1670.0 FT E(): 0 57.8% identity in 760 aa overlap and FT TR:Q9Z577(EMBL:AL035569) putative integral membrane export FT protein SC8D9.13 (748 aa), fasta scores opt: 1382 z-score: FT 1387.5 E():0 40.7% identity in 734 aa overlap. Also similar FT to a number of other putative MMPL family membrane proteins FT such as: Mycobacterium leprae SW:MMLB_MYCLE(EMBL:Z95398) FT putative membrane protein MMPL11 (1014 aa), fasta scores FT opt: 999 z-score: 1001.8 E(): 0 29.6% identity in 743 aa FT overlap. Contains multiple possible membrane spanning FT hydrophobic domains and a possible N-terminal signal FT sequence." FT /db_xref="GOA:Q9RKC1" FT /db_xref="InterPro:IPR000731" FT /db_xref="UniProtKB/TrEMBL:Q9RKC1" FT /protein_id="CAB59662.1" FT /translation="MATFLYKLGRLAFRRRHFVALIWVALLTLAGVGAASAPPAGNSSF FT SIPGTEAQKAFDLLEQRFPGASADGATARVVFKAPAGETMTDAGNKATVEKTVDELADG FT SEVASVADPYTGNAVSEDGTIAYASVKYDVSGMELEESTKDALEDAAQQARDAGLTVEI FT GGDALQAVPETGATEVIGIAVAAVVLVITFGSLVSAGLPLLTALIGVGIGVSSITALAS FT ALELGSTTSILAMMIGLAVGIDYALFIVSRYRAELAEGREREEAAGRAVGTAGSAVVFA FT GLTVVIALVGLAVVNIPMLTKMGIAAAGTVAIAVLIALTMIPALLGYAGRRVKPAGAKG FT KRLGRSRKGEPKPDRPAGQPKANLGTRWASFVVRRPLAVLLLGVIGLGAAAVPAASLEL FT GLPDDGSQPTSTTQRRAYDLLSEGFGPGFNGPLMVVVDAKGSDAPKDAFTDVEQRIKGL FT DGVVAVAPPAPNKGGDTATITVVPDSKPSSVQTEDLVHAIRDAGGDVEAKTGAETLVTG FT ATAMNIDVSQKLNDALVPYLVLVVGLAFLLLIVVFRSILVPLKAALGFLLSVMAALGAV FT VAVFQWGWLSGLMGVEETGPVMSMMPIFMVGVVFGLAMDYEVFLVTRMREAYVHGEKPN FT QAVVTGFKHGARVVTAAAVIMMAVFAGFIGSSESMVKMIGFGLAIAVFFDAFVVRMAIV FT PAVLALLGKKAWWLPKWLDRALPNVDVEGEGLRTAAERGTGPDEDRELVRT" FT CDS complement(121406..122005) FT /transl_table=11 FT /gene="SCO3167" FT /gene_synonym="SCE87.18c" FT /product="putative tetR-family transcriptional regulator" FT /note="SCE87.18c, possible tetR-family transcriptional FT regulator, len: 199 aa. Similar to many including: FT Propionibacterium freudenreichii TR:P72185(EMBL:U51164) FT repressor protein (HemR protein) (259 aa), fasta scores FT opt: 222 z-score: 276.8 E(): 4.8e-08 30.6% identity in 196 FT aa overlap and Streptomyces coelicolor FT TR:CAB45568(EMBL:AL079355) putative transcriptional FT regulator (fragment) SC4C6.04 (204 aa), fasta scores opt: FT 539 z-score: 660.1 E(): 2.2e-29 42.9% identity in 191 aa FT overlap. Contains a Pfam match to entry PF00440 tetR, FT Bacterial regulatory proteins, tetR family." FT /db_xref="GOA:Q9RKC0" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9RKC0" FT /protein_id="CAB59663.1" FT /translation="MTETATARRSRITPEREAELYEAVLDLLREVGYDALTMDAVAART FT RSSKATLYRQWGGKPELVVKAIRHNKPGEIGDVDTGSLRGDLHALMVREDDCTMEQNSA FT LMRGVAMALHQNPDLRQAFREQLIEPEMAEFQRVLQRAVDRGEIRADCPALDFLVHMMV FT GGFATRTLLDDQPPTREFLASYIDAVILPALGVSTH" FT misc_feature complement(121844..121948) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 22.10, E-value FT 0.00021" FT RBS complement(122014..122018) FT CDS 122154..125669 FT /transl_table=11 FT /gene="SCO3168" FT /gene_synonym="SCE87.19" FT /product="putative protease" FT /note="SCE87.19, possible protease, len: 1171 aa. Similar FT to Thermoplasma acidophilum TR:P96086(EMBL:U72850) tricorn FT protease (1071 aa) opt: 829 z-score: 857.6 E(): 0 28.1% FT identity in 1158 aa overlap and a protein of unknown FT function from Sulfolobus solfataricus TR:P95871(EMBL: FT Y08256) ORF C06024 (1068 aa), fasta scores opt: 846 FT z-score: 875.3 E(): 0 30.3% identity in 1150 aa overlap." FT /db_xref="GOA:Q9RKB9" FT /db_xref="InterPro:IPR015943" FT /db_xref="UniProtKB/Swiss-Prot:Q9RKB9" FT /protein_id="CAB59664.1" FT /translation="MRGARKSMGRVSYLRLPHLSGDQLCFVAEDDLWLASLDGPGRAWR FT LTVDRTKAGPPRFSPDGRHIAYTSWRTLVPEVHLVPVDGGPGRQLTHWGGLDTRVCGWS FT PPDPDGTTAVLAVASHGEPFSHLTWAYKVTPDGDPGRKLPWGPVTDIQAADLDGERRTL FT LLTGTPPHEPAAWKRYRGGATGRLWLHGERLLPDLGGHLSAPMFVGGRIAFLSDHEGVG FT NLYSCAQDGTGLRRHTDHDAFYARNAASDGTRVVYQCAGDLWIVDDLAPGSAPRRLDVR FT LSGPRAGRRTHQVPAAQHVGGISVDETGRASAVVVRGSLYWLTHRDGPARTIADTPGVR FT VRLPEMLGESGRIAYVTDAEGEDAVEISYLPRATGGRAARRLASGRLGRVLELVSDPAG FT DRLAVASHDGRLLILDVAEPDTEVTLALEAVDAGYPPDAGDEDAAGTAARADSAPDAPA FT EDTDARDIAAGTGTGDIADADAAAGGTVTPGSPGTPATAGGQVTELIRSVNGPVRDLAF FT SPDGTWLTWSHPGIGRTLRQIKMARIDGPEGTLVVDVTNGRFEDENPVFTRDGRYLAFL FT SWRGFDPVYDVHTGDLSFPLGCRPYLVPLSSATPSPFALNPEGRPAAGGLDPLEDEPGE FT GGAVMVEVEGLESRVTPFPVTASKYSALEPVAGGGLVWLRWPISGALGETFANPADPSE FT RPTLEHFNLAKAKKSELVDHLDWFRVSGDGSRLVVLDEGELRAVPASEVGDGDSTTWID FT LRRILHEVDPAAEWRQAYDEAGRLIRAYFWDPGMCGIDWDAVLDQYRPLLERVASPDEF FT ADLLREVLGELGTSHAYVVAARRNEGPAHYQRWQGLLGANLACRDGRWLVRRILPGDSS FT DSKARSPLAGTGIRDGAVLTHVDGRPVDPVLGPSPLLAGAGGTTVELTFAPAEGCQGPS FT RRVAVVPLVDERPLRYQDWVAKRREVVRELSGGRCGYLHIPDMGGSGWAQFNRDLRMEV FT SRPALIVDVRGNAGGHISELVIEKLTRTILGWDLTRDAQPVSYTSNAPRGPVVAVADEA FT TSSDGDMITAAFKLLRLGPVVGQRTWGGVVGMTGRHRLGDGSVITVPMNAAWFDAYGWS FT VENYGVAPDVEALRTPLDWAEGRYPVLDEAVRLALELLETNPPATPPGYEAVPDRSRPP FT LPPRE" FT CDS complement(125758..125985) FT /transl_table=11 FT /gene="SCO3169" FT /gene_synonym="SCE87.20c" FT /product="hypothetical protein SCE87.20c." FT /note="SCE87.20c, unknown, len: 75 aa. Note the predicted FT product of this CDS has an unusual amino acid composition FT with an excess of Arg, Asp and Gln residues." FT /db_xref="UniProtKB/TrEMBL:Q9RKB8" FT /protein_id="CAB59665.1" FT /translation="MGMKDQFQDKAERMQQQGKQRAEQARDQFQNRDRRRDEDEIDPSS FT PASRRRESEHQDPSSRRRDEDERLQDSFDA" FT RBS complement(125995..125999) FT CDS complement(126074..126967) FT /transl_table=11 FT /gene="SCO3170" FT /gene_synonym="SCE87.21c" FT /product="probable 3-oxoacyl-[acyl carrier protein] FT reductase" FT /note="SCE87.21c, probable 3-oxoacyl-[acyl carrier protein] FT reductase, len: 297 aa. Similar to many including: FT Mycobacterium tuberculosis TR:O33263 (EMBL:Z97559) probable FT oxidoreductase (293 aa), fasta scores opt: 672 z-score: FT 754.5 E(): 0 41.6% identity in 281 aa overlap and FT Escherichia coli SW:FABG_ECOLI (EMBL:M84991) FT 3-oxoacyl-[acyl carrier protein] reductase (244 aa), fasta FT scores opt: 354 z-score: 402.7 E(): 4.6e-15 31.3% identity FT in 195 aa overlap. Contains a Pfam match to entry PF00106 FT adh_short, short chain dehydrogenase and a Prosite hit to FT PS00061 Short-chain dehydrogenases/reductases family FT signature." FT /db_xref="GOA:Q9RKB7" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RKB7" FT /protein_id="CAB59666.1" FT /translation="MSRVSLEGRVAVVTGAARGVGELMARKLSARGVKVALVGLEPDEL FT KQVSARLHSDSDHWHADVTDHEAMARVAKEVKDRFGKVDIVVANAGVATGGPFVDSDPE FT SWRRVIEVNLIGSAVTARAFLPALLESRGYLLQIASLAALTPAPMMSAYCASKSGVEAY FT AHSLRGEVGHRGVKVGVGYLSWTDTDMVRGADQDDVMRELRQRLPWPTNRTYPLGPAVD FT RLVEGVERRSAHVYGQWWLRGMQGVRGYLPALVGTVGQREMRRFGDRLNGRRIGLVGAG FT GAADEHRPTRATTVRK" FT misc_feature complement(126401..126943) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 173.10, E-value 4.4e-48" FT misc_feature complement(126464..126550) FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT CDS complement(126964..127908) FT /transl_table=11 FT /gene="SCO3171" FT /gene_synonym="SCE87.22c" FT /product="putative hydrolase" FT /note="SCE87.22c, possible hydrolase, len: 314 aa: Similar FT to several e.g. Mycobacterium tuberculosis TR:O53321 (EMBL: FT AL021646) hypothetical 32.1 KD protein (299 aa), fasta FT scores opt: 261 z-score: 297.3 E(): 3.5e-09 31.7% identity FT in 281 aa overlap and Streptomyces lividans SW:PRXC_STRLI FT (EMBL: U02635) non-heme chloroperoxidase (EC 1.11.1.10) FT (275 aa), fasta scores opt: 241 z-score: 275.2 E(): 5.9e-08 FT 30.0% identity in 287 aa overlap. Contains a Pfam match to FT entry PF00561 abhydrolase, alpha/beta hydrolase fold." FT /db_xref="GOA:Q9RKB6" FT /db_xref="InterPro:IPR000073" FT /db_xref="UniProtKB/TrEMBL:Q9RKB6" FT /protein_id="CAB59667.1" FT /translation="MSRLLRVADGPYAPPVPARELTVTAADGARVHVEVHGPENAPAVV FT LAHGWCCSTAFWAAQIRELAADHRVIAYDQRGHGRSPANPAYGTEPLADDLEAVLEATL FT APGERAVIAGHSMGGMTLMAAATRPAVREHAAAVLLTSTGSARLVASATVVPMRAGRVR FT TWLTRRILGSRAPLGPVTPLARRILKYGTMGPGSAPHMVDACARIVHSCPSRVRHGWSQ FT VLDLLDLDHGVRELRMPAEIVVGTADRLTPPEHARALAAALPDCVGLTELPGVGHMTPV FT EAPDLVTGKIRALAATYIPSARGERAVPVEESA" FT RBS complement(126973..126977) FT misc_feature complement(127024..127707) FT /note="Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold, score 59.10, E-value 9.5e-14" FT CDS complement(127905..129464) FT /transl_table=11 FT /gene="SCO3172" FT /gene_synonym="SCE87.23c" FT /product="putative monooxygenase" FT /note="SCE87.23c, probable monooxygenase, len: 519 aa. FT Highly similar to many including: Acinetobacter sp FT SW:CYMO_ACISP (EMBL:M19029) cyclohexanone monooxygenase (EC FT 1.14.13.22) (542 aa), fasta scores opt: 459 z-score: 510.7 FT E(): 4.5e-21 28.0% identity in 511 aa overlap and FT Mycobacterium tuberculosis TR:O53294(EMBL:AL021287) FT monooxygenase (524 aa), fasta scores opt: 1522 z-score: FT 1690.4 E():0 47.4% identity in 485 aa overlap. Contains a FT Pfam match to entry PF00743 FMO-like, Flavin-binding FT monooxygenase-like." FT /db_xref="GOA:Q9RKB5" FT /db_xref="InterPro:IPR003953" FT /db_xref="UniProtKB/TrEMBL:Q9RKB5" FT /protein_id="CAB59668.1" FT /translation="MAEHEQVHEHVRVAVIGSGFGGLGAAVRLRREGITDFVVLERAGS FT VGGTWRDNSYPGCACDVPSHLYSFSFAPNPEWPRTFSGQEHIRAYLEHVADTFGLRPHL FT RFDSEVKRMAWDTEQLRWEIETVRGTLTADVVVSATGPLSDPKVPDIPGLDTFPGKVFH FT SARWDHDYDLAGQRVAMIGTGASAIQIVPSIQPKVDRLTLFQRTPAWVMPRVDRAISGA FT ERALHRALPATTKLRRGLLWGIRELQVQAFTKHPNELGFVEQIAKRNMGAAIKDPALRA FT KLTPDYRIGCKRILLSSTYYPALAKPNVDVVASGLSEVRGSTLVAADGTEAEADAIVFG FT TGFHVTDMPIAERVVGADGRTLAETWKGGMEALRGGTAAGFPNFMTVIGPNTGLGNSSM FT ILMIESQLNYLADYLRQLNVLGGRTALDPRPAAVRNWNHRVQERMKRTVWNTGGCTSWY FT LDASGRNTTVWPGTTAEFRRETRRVDLAEYQVLRPAPAQVGAKAAEADTGADTGADAEV FT SA" FT RBS complement(127913..127920) FT misc_feature complement(127959..129431) FT /note="Pfam match to entry PF00743 FMO-like, Flavin-binding FT monooxygenase-like, score 5.70, E-value 1.3e-22" FT RBS complement(129472..129476) FT CDS 129624..130271 FT /transl_table=11 FT /gene="SCO3173" FT /gene_synonym="SCE87.24" FT /product="putative merR-family transcriptional regulator" FT /note="SCE87.24, possible merR-family transcriptional FT regulator, len: 215 aa. Similar to two other putative FT transcriptional regulators from Streptomyces coelicolor FT TR:CAB40683 (EMBL:AL049587) SC5F2A.16C (251 aa), fasta FT scores opt: 210 z-score: 257.9 E(): 5.4e-07 32.3% identity FT in 217 aa overlap and TR:O86531 (EMBL:AL031124) SC1C2.31C FT (214 aa), fasta scores opt: 176 z-score: 218.8 E(): 8.2e-05 FT 30.4% identity in 191 aa overlap. Contains a Pfam match to FT entry PF00376 merR, Bacterial regulatory proteins, merR FT family with the putative helix-turn-helix motif situated FT between residues 8..29 (+3.90 SD)." FT /db_xref="GOA:Q9RKB4" FT /db_xref="InterPro:IPR000551" FT /db_xref="UniProtKB/TrEMBL:Q9RKB4" FT /protein_id="CAB59669.1" FT /translation="MTEKREYRMAELARLAGITVRTVRFYRERKLIPPPRREGRIAWYD FT DHHLARLRTIAALLERGHTLNGIAELADAFDHGRDVGDLLGLGEPTEETPVRLTPEELA FT ARFEGEVTPENLAAAMELGYLGTDGDELVHISHRLLEVSSALVREGIPLGEVLQAGVRV FT REHADALAELFADLILRHAPEPELHRLRPLARSVVEAELSLALDRRMRKQTD" FT misc_feature 129651..129740 FT /note="Pfam match to entry PF00376 merR, Bacterial FT regulatory proteins, merR family, score 26.70, E-value FT 0.00029" FT CDS complement(130290..131114) FT /transl_table=11 FT /gene="SCO3174" FT /gene_synonym="SCE87.25c" FT /product="putative exodeoxyribonuclease (EC 3.1.11.2) FT (putative secreted protein)" FT /note="SCE87.25c, possible exodeoxyribonuclease (EC FT 3.1.11.2) (putative secreted protein), len: 274 aa. Highly FT similar to several e.g. Bacillus subtilis SW:EXOA_BACSU FT (EMBL:D26185) exodeoxyribonuclease (EC 3.1.11.2) (252 aa), FT fasta scores opt: 592 z-score: 694.3 E(): 2.7e-31 38.6% FT identity in 267 aa overlap and Methanobacterium FT thermoautotrophicum TR:O26314 (EMBL:AE000808) FT exodeoxyribonuclease (257 aa), fasta scores opt: 674 FT z-score: 789.1 E():0 41.6% identity in 262 aa overlap. Also FT similar to Pseudomonas aeruginosa TR:Q51380 (EMBL:U38241) FT catabolite repression control protein (259 aa), fasta FT scores opt: 601 z-score: 704.5 E(): 7.2e-32 39.3% identity FT in 267 aa overlap. Contains a Pfam match to entry PF01260 FT AP_endonucleas1, AP endonuclease family 1. Note that the FT translational start site may be located at residue 8. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="GOA:Q9RKB3" FT /db_xref="HSSP:1BIX" FT /db_xref="InterPro:IPR005135" FT /db_xref="UniProtKB/TrEMBL:Q9RKB3" FT /protein_id="CAB59670.1" FT /translation="MCRYRAGMLTVTSVNVNGLRAAAKKGFVEWLAGTSADVLCLQEVR FT AEPHQLPDHAGAPEGWHVTHAPAAAKGRAGVSLYTRREPDAVRVGFGSTEFDTSGRYVE FT ADLPGVTVASLYLPSGEVGTERQDEKVRFMGEFLAYLKELRERAAAQGREVVVCGDWNI FT AHREADLKNWRANKKNSGFLPEEREWLGRVLDPAEGGYVDVVRALHPDVEGPYSWWSYR FT GRAFGNDAGWRIDYHVSTPGLAAKAVKGYVERAATHAERWSDHAPVTVVYDR" FT misc_feature complement(130296..131078) FT /note="Pfam match to entry PF01260 AP_endonucleas1, AP FT endonuclease family 1, score 207.80, E-value 1.6e-58" FT RBS complement(131129..131132) FT RBS 131155..131158 FT CDS 131162..131647 FT /transl_table=11 FT /gene="SCO3175" FT /gene_synonym="SCE87.26" FT /product="putative acetyltransferase" FT /note="SCE87.26, possible acetyltransferase, len: 161 aa. FT Similar to Azospirillum brasilense SW:IAAT_AZOBR FT (EMBL:X57853) IAA acetyltransferase (EC 2.3.1.-) (153 aa), FT fasta scores opt: 224 z-score: 280.9 E(): 2.8e-08 36.7% FT identity in 139 aa overlap. Contains a Pfam match to entry FT PF00583 Acetyltransf, Acetyltransferase (GNAT) family." FT /db_xref="GOA:Q9RKB2" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9RKB2" FT /protein_id="CAB59671.1" FT /translation="MNIRRVPFDHPDAVKLNDEVQAEYDVRYGDGGDATHLDPSDFAPP FT NGQYLIAYDENDVPVASGGWRSQDANDEGNLDGDAELKRMFVIEQVRGRGLARRILAAL FT EEDARAAGRTRMVLETGTKQPEAVALYTSSGYEPCGKFGYYRFHEDSLCYAKALRVR" FT misc_feature 131168..131572 FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 51.50, E-value FT 1.9e-11" FT CDS complement(131667..133418) FT /transl_table=11 FT /gene="SCO3176" FT /gene_synonym="SCE87.27c" FT /product="putative membrane protein" FT /note="SCE87.27c, possible membrane protein, len: 583 aa. FT Contains possible membrane spanning hydrophobic domains and FT a possible N-terminal signal sequence." FT /db_xref="InterPro:IPR019931" FT /db_xref="UniProtKB/TrEMBL:Q9RKB1" FT /protein_id="CAB59672.1" FT /translation="MRPSSLRSPWTRAAVAGAAAAGLAAAGLAGVAHAADDQPPLPVTI FT TGPDRVDLALDGAEGEPGRPQIELGLTGPGEYDPDSDTDPEPIPNSGYKVTIDATALKG FT FAKVGLPDSCDVDGLVAVCRESSLYPGDIHNPFWDIRLDLLDTAEAGDHGTIKVTGKGE FT GLEFNKHTVDVLVGGPELLKKKLPAEPAGFRPGDTYDAPLGFRNVGSMPAHGVVLRFAG FT TRGLSFPESYDNCSYAEENKDNLIRYRQVALCTFEGEFLHGMAYELSEPVEVKTADFAL FT GDIFTYGFDAVGAEAADELRAGAGHRKKTGRTLTLEPVESGHVGDYSKYAEIDLPTQNT FT YDLDLTGARVAGEQGETVTVDVRMSNHGPAWIGSLRAGGEPLGFSVQIPEGASVVDSPC FT NPVNDESPSEYLCFTNTPFLEDDARTFPFELRIDKVVAGAKGKIALPDHDNPWEGDPSN FT DTGWIVLNGTGDEETPGDSGGGTGGPDTTGGTDATGGPQTTGGTGTTGGSDTAGGTTGG FT TSTAGTTGSTTGGTTGGQSPQGGRGGVLASTGSTVLLGSAGAALALAAGGVLYAVSRRR FT RTGGTAA" FT stem_loop complement(133586..133630) FT /note="possible stem loop with 100% matches over 20 bases FT and a loop of 5 bases" FT tRNA complement(133639..133712) FT /note="tRNA Ala anticodon CGC, Cove score 77.02" FT CDS complement(133768..135036) FT /transl_table=11 FT /gene="SCO3177" FT /gene_synonym="SCE87.28c" FT /product="putative membrane protein" FT /note="SCE87.28c, possible membrane protein, len: 422. FT Contains possible membrane spanning hydrophobic domains and FT a possible N-terminal signal sequence. Also contains a FT probable coiled-coil between residues 213..240 (28 FT residues)." FT /db_xref="UniProtKB/TrEMBL:Q9RKB0" FT /protein_id="CAB59673.1" FT /translation="MSSSGLIYAVIVGAWAAYLVPMWLRRQDELNEARPTERFSTAIRL FT LSGRAGMERRYAKDLRSRPADEAGPDADAPDAVTDSVDVRAFAVSRTRRHTRPTPPRQA FT AERPETARPRAGGPEDGPRPGQSAEPGRQAGTGAAPARERVPQARRAPVSPGAAARARR FT SKALARRRRTTVMLFLAFTLGSVVAAVGGLAFLWAPGVPAVLLSAYIAHLRAQERRRFA FT FQMDRRQAEAAAQRLRDRDPRPRRRGPAPAAPGTVGDLDAEEPDDGPETESGAGMSALA FT ADRRALVEQTDHAEWVDQQRERRGRPQGDSWDPVPVPLPTYVTAPVAPRATPDVDLAAP FT DAWSSARSSAVAPDQEDAARASGADRDRPADAPAHAPAEERPEAPARSGARRAASARRA FT RERGRTPLFDQYDDGDRPRAANE" FT CDS complement(135213..135863) FT /pseudo FT /transl_table=11 FT /gene="SCO3178" FT /gene_synonym="SC87.29c" FT /product="putative acetyltransferase (pseudogene)." FT /note="SCE87.29c, possible acetyltransferase, pseudogene, FT len: 217 aa. The high level of sequence similarity to FT various database entries extends upstream of the last FT possible translational start codon suitable for this CDS. FT Highly similar to several including: Escherichia coli FT SW:RIMJ_ECOLI (EMBL:X06118) ribosomal-protein-alanine FT acetyltransferase (EC 2.3.1.128) (194 aa), fasta scores FT opt: 266 z-score: 321.9 E(): 1.5e-10 30.0% identity in 190 FT aa overlap and Mycobacterium leprae TR:Q9Z5F9 FT (EMBL:AL035500) putative acyltransferase (218 aa), fasta FT scores opt: 560 z-score: 665.1 E(): 1.1e-29 45.4% identity FT in 194 aa overlap." FT CDS complement(135869..136408) FT /transl_table=11 FT /gene="SCO3179" FT /gene_synonym="moaB" FT /product="molybdenum cofactor biosynthesis protein FT (putative secreted protein)" FT /note="SCE87.30c, moaB, probable molybdenum cofactor FT biosynthesis protein (putative secreted protein), len: 179 FT aa. Highly similar to many including: Mycobacterium FT tuberculosis TR:O53877 (EMBL:AL022004) putative FT molybdopterin biosynthesis Mog protein (160 aa), fasta FT scores opt: 617 z-score: 660.3 E(): 2.1e-29 60.0% identity FT in 160 aa overlap and the C-terminus of the Synechococcus FT sp MoaC, MoaB fusion protein SW:MOCB_SYNP7 (EMBL:X99625) FT molybdenum cofactor biosynthesis protein CB (319 aa), fasta FT scores opt: 401 z-score: 430.6 E(): 1.3e-16 41.5% FT identity in 171 aa overlap. Contains a Prosite hit to FT PS01078 Molybdenum cofactor biosynthesis proteins signature FT 1 and a possible N-terminal signal sequence." FT /db_xref="GOA:Q9RKA9" FT /db_xref="HSSP:1O8O" FT /db_xref="InterPro:IPR008284" FT /db_xref="UniProtKB/TrEMBL:Q9RKA9" FT /protein_id="CAB59675.1" FT /translation="MTPDAGVGGALLGPYAALVVTASNRAAAGVYEDRGGPLIAEGLRR FT FGFAVDGPQVVPDGDPVRAALRAGVEAGFDVIVTTGGTGISPTDRTPEATRAVIDREVP FT GIAEAIRAYGRDKVPAAALSRGLAGVAGGTLIVNLPGSSGGVKDGLAVLEPLLKHAVDQ FT IRGGDHPRPASGGGAS" FT misc_feature complement(136142..136183) FT /note="PS01078 Molybdenum cofactor biosynthesis proteins FT signature 1" FT CDS complement(136405..136917) FT /transl_table=11 FT /gene="SCO3180" FT /gene_synonym="moaC" FT /product="molybdenum cofactor biosynthesis protein" FT /note="SCE87.31c, moaC, probable molybdenum cofactor FT biosynthesis protein, len: 170 aa. Highly similar to many FT including: Mycobacterium tuberculosis TR:O53876 FT (EMBL:AL022004) MoaC protein (167 aa), fasta scores opt: FT 627 z-score: 742.2 E():0 61.0% identity in 164 aa overlap FT and Escherichia coli SW:MOAC_ECOLI(EMBL:X70420) molybdenum FT cofactor biosynthesis protein C (160 aa), fasta scores opt: FT 459 z-score: 547.5 E(): 4e-23 54.2% identity in 153 aa FT overlap. Contains a possible membrane spanning hydrophobic FT domain." FT /db_xref="GOA:Q9RKA8" FT /db_xref="HSSP:1EKR" FT /db_xref="InterPro:IPR002820" FT /db_xref="UniProtKB/Swiss-Prot:Q9RKA8" FT /protein_id="CAB59676.1" FT /translation="MSTQDRPSGSGQDPQDRLTHIDEAGAARMVDVSGKDVTARTARAS FT GRVLVAPRVVELLRGEGVPKGDALATARIAGIMGAKRTPDLIPLCHPLSVSGVKLDLSV FT ADDAVEITATVRTTDRTGVEMEALTAVSVAALTVVDMVKAVDKGAVITDVRVEQKTGGK FT SGDWTRS" FT CDS complement(137004..138278) FT /transl_table=11 FT /gene="SCO3181" FT /gene_synonym="moeA" FT /product="molybdopterin biosynthesis protein." FT /note="SCE87.32c, moeA, probable molybdopterin biosynthesis FT protein. len: 424 aa. Highly similar to many e.g. FT Mycobacterium tuberculosis SW:MOEA_MYCTU (EMBL:Z94752) FT molybdopterin biosynthesis protein (426 aa), fasta scores FT opt: 795 z-score: 812.4 E():0 39.3% identity in 438 aa FT overlap. Contains a Pfam match to entry PF00994 FT MoCF_biosynth, Molybdenum cofactor biosynthesis protein." FT /db_xref="GOA:Q9RKA7" FT /db_xref="HSSP:1G8L" FT /db_xref="InterPro:IPR005110" FT /db_xref="UniProtKB/TrEMBL:Q9RKA7" FT /protein_id="CAB59677.1" FT /translation="MQDHLDDVLATVRPLDPIELNLLDAQGCVLVDDITVPLSLPPFDN FT SSMDGYAVRVTDVAGASEEFPAVLEVVGDVAAGQTDPIAVGPGQAARIMTGAPLPPGAE FT AVVPVEWTDGGSGEGPVAGMRARSLAPEGAEGHVQVYRPAEERAHVRAKGSDVRSGDRA FT LAAGTVLGPPQIGLLAAIGRGTVRVRPRPRVVVLSTGSELVQPDEQLAPGQIYDSNSFA FT LTAAARDAGAIAYRVGAVADDAETLRATIEDQLVRADLMVTTGGVSVGAYDVVKEALAH FT VGDEDEPGGGVDFRKLAMQPGKPQGFGSVGPDHTPLLALPGNPVSSYVSFELFVRPAIR FT TLMGLPDVHRPTVTASLAADKALTSPKGRRQFLRGSHAGGSVTPVGGSGSHLVAALAQA FT NALIVVPEDTESVEPGTEVEVVLLG" FT misc_feature complement(137010..138278) FT /note="Pfam match to entry PF00994 MoCF_biosynth, FT Molybdenum cofactor biosynthesis protein, score 463.60, FT E-value 1.6e-135" FT CDS complement(138350..139261) FT /transl_table=11 FT /gene="SCO3182" FT /gene_synonym="gtaB" FT /product="UTP-glucose-1-phosphate uridylyltransferase" FT /note="SCE87.33c, gtaB, UTP-glucose-1-phosphate FT uridylyltransferase, len: 303 aa. Highly similar to many FT proteins belonging to the prokaryotic UDPGP family e.g. FT Bacillus subtilis SW:GTAB_BACSU (EMBL:L12272) FT UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) FT (292 aa), fasta scores opt: 907 z-score: 1054.0 E(): 0 FT 47.1% identity in 293 aa overlap. Contains a Pfam match to FT entry PF00483 NTP_transferase, Nucleotidyl transferase." FT /db_xref="GOA:Q9RKA6" FT /db_xref="HSSP:1FXO" FT /db_xref="InterPro:IPR005835" FT /db_xref="UniProtKB/TrEMBL:Q9RKA6" FT /protein_id="CAB59678.1" FT /translation="MTQSHPRISKAVIPAAGLGTRFLPATKATPKEMLPVVDKPAIQYV FT VEEAVTAGLGDVLMVTGRNKRPLEDHFDRNYELESALQKKGDASRLAKVQESSDLAMMH FT YVRQGDPKGLGHAVLCAAPHVGHEPFAVLLGDDLIDPRDPLLQRMIDVQEQYGGSVIAL FT MEVAPEQIHLYGCAAVESTADSDVVKVGGLVEKPDPADAPSNYAIIGRYVLDPHVFDIL FT RKTEPGRGGEIQLTDALQQLAEDESVGGPVHGVVFKGRRYDTGDRGDYLRAIVRLACER FT EDLGPDFRTWLRSYVAEEMQGR" FT misc_feature complement(138422..139234) FT /note="Pfam match to entry PF00483 NTP_transferase, FT Nucleotidyl transferase, score 61.50, E-value 1.9e-14" FT RBS 139345..139348 FT CDS 139355..139969 FT /transl_table=11 FT /gene="SCO3183" FT /gene_synonym="SCE87.34" FT /product="conserved hypothetical protein SCE87.34" FT /note="SCE87.34, unknown, len: 204 aa. Similar to many FT proteins of undefined function including: Escherichia coli FT SW:YGFA_ECOLI (EMBL:M12965) hypothetical 21.1 KD protein in FT SSR-SERA intergenic region (182 aa), fasta scores opt: 298 FT z-score: 347.9 E(): 5.3e-12 35.0% identity in 180 aa FT overlap. Also weakly similar to several Eukaryotic proteins FT such as: Homo sapiens SW:FTHC_HUMAN (EMBL: L38928) FT 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (202 FT aa), fasta scores opt: 183 z-score: 217.8 E(): 9.3e-05 FT 23.4% identity in 188 aa overlap. Contains a Pfam match to FT entry PF01812 5-FTHF_cyc-lig." FT /db_xref="GOA:Q9RKA5" FT /db_xref="InterPro:IPR019793" FT /db_xref="UniProtKB/TrEMBL:Q9RKA5" FT /protein_id="CAB59679.1" FT /translation="MPHNDPADGPGKRLLRRDLLAARNRMTPDDVRESADALARRALEL FT PEVAGAHAVAAYVSVGAEPGTLALLDALRARGVRVLLPALLPDNDLDWGEYTGEGSLAR FT VRHGGRMELFEPAGERLGPEAVTRADVVLLPGVAVDGRGLRLGRGGGSYDRVLARLEVA FT GARPALLVLLYDGEVVEHVPAEPHDRPVDAVVTPSGVRRFR" FT misc_feature 139418..139945 FT /note="Pfam match to entry PF01812 5-FTHF_cyc-lig, , score FT 108.30, E-value 1.5e-28" FT stem_loop 139989..140038 FT /note="possible stem loop with 100% matches over 24 bases FT and a loop of 2 bases." FT CDS complement(140058..142868) FT /transl_table=11 FT /gene="SCO3184" FT /gene_synonym="SCE22.01c" FT /gene_synonym="SCE87.35c" FT /product="putative penicillin acylase (EC 3.5.1.11)." FT /note="SCE22.01c, possible secreted penicillin acylase FT (fragment), len: >162 aa; similar to C-terminal region of FT SW:PAC2_PSES3 (EMBL:M18278) Pseudomonas sp. penicillin FT acylase II precursor (EC 3.5.1.11) AcyII, 773 aa; fasta FT scores: opt: 291 z-score: 347.5 E(): 6.8e-12; 39.1% FT identity in 110 aa overlap. Contains possible N-terminal FT signal peptide sequence" FT /note="SCE87.35c, possible penicillin acylase (EC FT 3.5.1.11) partial CDS, len: > 808 aa. Similar to many FT penicillin acylases including: Pseudomonas sp. (strain FT SE83) SW:PAC2_PSES3c (EMBL:M18278) penicillin acylase II FT precursor (EC 3.5.1.11) (penicillin amidase II) (773 aa), FT fasta scores opt: 308 z-score: 319.7 E(): 2e-10 27.2% FT identity in 815 aa overlap. Contains a Pfam match to entry FT PF01804 Penicil_amidase and a 12x 'TG' repeat region FT between residues 148..172." FT /db_xref="GOA:Q8CJX4" FT /db_xref="HSSP:1PNK" FT /db_xref="InterPro:IPR002692" FT /db_xref="UniProtKB/TrEMBL:Q8CJX4" FT /protein_id="CAD55496.1" FT /translation="MPPTTTASTGQQAGTSGRKKARKGRKGRLLVLVLVLALIGGLAYG FT AYWSISTVRASFPQTKGSITLDGLSGPVDVKRDGYGIPQVYASTEEDLFMAQGYVQAQD FT RFYEMDVRRHMTAGRLSEMFGKSQIDNDEFLRTLGWHRVAKKEYDEKLSDSTKKYLQAY FT SKGVNAYLKGKDGGDLSLEYAALGFTNDYKPQAWTPVDSVAWLKAMAWDLRGNMQDEVD FT RALMTSRLGPKQIADLYPAYPYDRNKAIVQEGQYDELTETFDGGGASGGGESDGTGTGT FT GTGTGTGTGTGTGTGTGTGSGSALEGQLAGLQNVLDNVPTAVGVNGNGIGSNSWVVSGK FT HTITGKPLLANDPHLSPSLPSVWYQMGLHCRTVSDKCRYDVAGYTFAGMPGVVVGHNQE FT IAWGLTNSGADVTDLYLEKITGEGYQYDGKVVPFETREETIKVAGGDSKKIVVRETNNG FT PLLSDRDDELVKTGKKATVETAAPDRGDGYGVALRWTALEAGTSMDAVFAIDRARNWDD FT FREAATLFDVPSQNLVYADEEHIGYTLPGRIPVRAEGHDGSVPAPGWDPKFRWTGEYID FT QDELPYEYDPERGYIVTANQAVVDADKYPYTLTTDWGYGARSQRITSLIEQKIKDGGKI FT STDDMRQMQLDNSSEMAKLLVPQLLKIDIADKDVREAQKLLEGWDYTQDADSAAAAYFN FT AVWRNILKLAFGNKLPKELRVEGQCLWVDPVNTTGPADETNKVRECGQRDADQAQPDGG FT DRWFEVVRTLLEKPKSDWWTTPANGTRKGADHNRDDLFKRAMTDARWELTAKLGKDIDT FT WNWGRLHRLFLKNQTLGTEGPGFLKYALNRGPWKLSGGEAAVNASGWNAAGGYGVIWVP FT SMRMVVNLGDLDKSRWINLTGASGHAYSAHYTDQTDKWANGELLPWSFTRKAVDESTSD FT TLVLKP" FT misc_feature complement(140082..142484) FT /note="Pfam match to entry PF01804 Penicil_amidase, , score FT 53.30, E-value 5.2e-12" FT repeat_region complement(141970..142041) FT /note="degenerate repeat region containing 6x CACGGG, 4x FT CACCGG, 1x TACCGG and 1x TACGGG." FT CDS 143183..144730 FT /transl_table=11 FT /gene="SCO3185" FT /gene_synonym="SCE22.02" FT /product="putative Na+/H+ antiporter" FT /note="SCE22.02, possible Na+/H+ antiporter, len: 515 aa; FT similar to TR:Q9XAJ9 (EMBL:AL079348) Streptomyces FT coelicolor putative Na(+)/H(+) antiporter SC66T3.14c, 514 FT aa; fasta scores: opt: 1828 z-score: 1992.7 E(): 0; 55.1% FT identity in 497 aa overlap. Contains Pfam match to entry FT PF00999 Na_H_Exchanger, Sodium/hydrogen exchanger family FT and possible hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9KYW0" FT /db_xref="InterPro:IPR006037" FT /db_xref="UniProtKB/TrEMBL:Q9KYW0" FT /protein_id="CAB90969.1" FT /translation="MRCARERERPLTVHHLNQLLLVCSLVLLIAVAAVRISSRSGLPSL FT LVYLAIGVAMGQDGIGDIQFDNAELVQVIGYGALVVILAEGGLGTKWKEAKPALPAASA FT LALGGVAVSVGVTAAGAHYLTGLEWRQALIVGAVVSSTDAAAVFSVLRRIPLPKRITGT FT LEAESGFNDAPVVILVVAFSTAGPIEHWYVLLGEIALELAIGAAIGLAVGWLGSWGLKH FT VALPASGLYPIAVMSIAIAAYAAGAMAHGSGFLAVYLASMVMGNARLPHWPATRGFADG FT LGWLAQIGMFVLLGLLVTPHELGDDILPALVIGLVLTMVARPLSVVLCLVPFRVPWQEQ FT ALMSWAGLRGAVPIILATIPMVEGVAGSHRIFNIVFVLVVVYTLVQGPTLPWLARKLRL FT GKGDEAADLGIESAPLERLRGHLLSVTIPEGSRMHGVEVNELRLPTGAAVTLVVRDGTS FT FVPLPTTGLRRGDELLVVATDPVRDAAEARLRAVGHGGKLAGWLGTGGTEGARGNRR" FT misc_feature 143234..144385 FT /note="Pfam match to entry PF00999 Na_H_Exchanger, FT Sodium/hydrogen exchanger family, score 73.90, E-value FT 3.4e-18" FT CDS 144979..146244 FT /transl_table=11 FT /gene="SCO3186" FT /gene_synonym="SCE22.03" FT /product="putative ABC transporter integral membrane FT protein" FT /note="SCE22.03, possible ABC transporter integral membrane FT protein, len: 421 aa; similar to TR:O50532 (EMBL:AL009204) FT Streptomyces coelicolor hypothetical 41.1 kD protein FT SC9B10.25c, 393 aa; fasta scores: opt: 721 z-score: 787.1 FT E(): 0; 34.7% identity in 363 aa overlap. Contains match to FT Prosite entry PS00211 ABC transporters family signature and FT possible hydrophobic membrane spanning regions" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9KYV9" FT /protein_id="CAB90970.1" FT /translation="MASTVTRPGYGQLLRTRGAWTFLLPGFAARQPFAMLTLSIVLLVQ FT HTTGSYGVAGAAAAVTGVSMAVFAPYSGRLADRYGQRAVLLPGVLVHTASGLTLTVLAL FT ADAPLWALFLAAVPTGASVPQVGPMVRARWAVQLKDSPLMSTAAAFESVTDELTFVLGP FT LVATALCTAVDPAAGLVTEAALTLVGGLLFAARKSTEPKVGSADGGHARVEHVSALRVP FT GVRVLIVAFLGIGSVFGGMQVSLAAFTESIGEPGLNGVLYGVFAAGNMISGLACGAIAW FT KVAPQRRLLVGYAALALTASGLWAAHSVLVLAGLGLLVGMCVAPAIVTGYTLVEDLVPA FT GARTEAFTWLTGAVALGQAAAVTVAGQLEDRFRDGAGFLVPMGGTVLALAVLVALRSRL FT ATRSHGRTVARGVGHRAPATVD" FT misc_feature 146038..146082 FT /note="PS00211 ABC transporters family signature" FT RBS 146301..146306 FT CDS 146312..146644 FT /transl_table=11 FT /gene="SCO3187" FT /gene_synonym="SCE22.04" FT /product="conserved hypothetical protein SCE22.04" FT /note="SCE22.04, hypothetical protein, len: 110 aa; similar FT to TR:O05574 (EMBL:Z94752) Mycobacterium tuberculosis FT hypothetical 11.4 kD protein MTCI237.05c, 110 aa; fasta FT scores: opt: 379 z-score: 372.3 E(): 2.8e-13; 52.3% FT identity in 107 aa overlap. High content in serine amino FT acid residue in C-terminal domain" FT /db_xref="InterPro:IPR013429" FT /db_xref="UniProtKB/TrEMBL:Q9KYV8" FT /protein_id="CAB90971.1" FT /translation="MPTYQYQCTECGEGLEAVQKFTDDALTECPNCQGRLKKVFSAVGI FT VFKGSGFYRNDSRGSSSSSSPASSSSKTASSSSSDSGSSSSSSASSSGSGSSSGSGSSS FT AGTTAA" FT misc_feature 146489..146629 FT /note="serine amino acid residues rich region" FT CDS 146775..147617 FT /transl_table=11 FT /gene="SCO3188" FT /gene_synonym="SCE22.05" FT /product="putative methylthioadenosine phosphorylase" FT /note="SCE22.05, possible methylthioadenosine FT phosphorylase, len: 280 aa; similar to TR:CAB49985 FT (EMBL:AJ248286) Pyrococcus abyssi methylthioadenosine FT phosphorylase related (MtaP), 265 aa; fasta scores: opt: FT 711 z-score: 861.9 E(): 0; 43.4% identity in 265 aa overlap FT and to SW:MTAP_HUMAN (EMBL:U22233) Homo sapiens FT 5'-methylthioadenosine phosphorylase (EC 2.4.2.28) FT (MTAPase) MtaP, 283 aa; fasta scores: opt: 653 z-score: FT 791.7 E(): 0; 38.2% identity in 254 aa overlap. Contains FT Pfam match to entry PF00896 Mtap_PNP, phosphorylases family FT 2" FT /db_xref="GOA:Q9KYV7" FT /db_xref="HSSP:1CB0" FT /db_xref="InterPro:IPR010044" FT /db_xref="UniProtKB/TrEMBL:Q9KYV7" FT /protein_id="CAB90972.1" FT /translation="MANKVKAEIGVIGGSGFYSFLDDVTEVRVDTPYGPPSDSLFLGEV FT AGRRVAFLPRHGRGHHLPPHRINYRANLWALRSVGARQVLGPCAVGGLRPEYGPGTLLV FT PDQFVDRTRSRPSTYFDGLPMPDGTVPNVVHVSLADPYCPTGRAAALKAARGREWEPVD FT GGTLVVVEGPRFGTRAESLWHRAQGWSVVGMTGHPEAALARELELCYTSLTLVTDLDAG FT AESGEGVSHEEVLRVFAANVDRLRGVLFDAVAALPASGERDCPCGAALGGMDPGIALP" FT repeat_region 146799..147428 FT /note="Pfam match to entry PF00896 Mtap_PNP, phosphorylases FT family 2, score 301.80, E-value 8.1e-87" FT CDS 147879..148358 FT /transl_table=11 FT /gene="SCO3189" FT /gene_synonym="SCE22.06" FT /product="putative membrane protein" FT /note="SCE22.06, possible membrane protein, len: 159 aa. FT Contains possible hydrophobic membrane spanning region and FT high content in alanine amino acid residues" FT /db_xref="UniProtKB/TrEMBL:Q9KYV6" FT /protein_id="CAB90973.1" FT /translation="MPQFAPVRVRGGRHRLHRLVRHRRRALAAGLVVTAAALVAAGPHP FT GAGGQETRRARGHPVADPVGERPATRFVAAPVRIADAATVRLLRPGDRVDVVAAGDGGA FT DDASVVARGVRVTKVPEPVADPAAGGALVVVSVPRATAHRLVGAGTTERLAVTLC" FT RBS 148454..148459 FT CDS 148470..148940 FT /transl_table=11 FT /gene="SCO3190" FT /gene_synonym="SCE22.07" FT /product="putative mechanosensitive channel" FT /note="SCE22.07, probable mechanosensitive channel, len: FT 156 aa; similar to TR:Q9Z5G4 (EMBL:AL035500) Mycobacterium FT leprae putative gated mechanosensitive ion channel MscL, FT 154 aa; fasta scores: opt: 248 z-score: 308.9 E(): FT 9.6e-10; 38.1% identity in 147 aa overlap and to FT SW:MSCL_CLOPE (EMBL:D50309) Clostridium perfringens FT large-conductance mechanosensitive channel MscL, 152 aa; FT fasta scores: opt: 216 z-score: 271.1 E(): 1.2e-07; 34.7% FT identity in 124 aa overlap. Contains Pfam match to entry FT PF01741 MscL, Large-conductance mechanosensitive channel, FT MscL and match to Prosite entry PS01327 Large-conductance FT mechanosensitive channels mscL family signature. Contains FT also possible hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9KYV5" FT /db_xref="HSSP:1MSL" FT /db_xref="InterPro:IPR019823" FT /db_xref="UniProtKB/TrEMBL:Q9KYV5" FT /protein_id="CAB90974.1" FT /translation="MSEKNEPSVWQGFKAFLMRGNVIDLAVAVVIGAAFTKIVNSVVDG FT VINPLVGAFGTQSLDSYSSCLKGPCTGTGDSATGVRILWGSVLGATLTFLITAAVVYFL FT MVLPMSKYLARQEARRKAKESAEEVIEVSELEVLKEIRDALIAQRGSGHDRP" FT misc_feature 148494..148916 FT /note="Pfam match to entry PF01741 MscL, Large-conductance FT mechanosensitive channel, MscL, score 101.30, E-value FT 1.9e-26" FT misc_feature 148524..148565 FT /note="PS01327 Large-conductance mechanosensitive channels FT mscL family signature" FT CDS complement(148981..149157) FT /transl_table=11 FT /gene="SCO3191" FT /gene_synonym="SCE22.08c" FT /product="hypothetical protein SCE22.08c" FT /note="SCE22.08c, unknown, len: 58 aa" FT /db_xref="UniProtKB/TrEMBL:Q9KYV4" FT /protein_id="CAB90975.1" FT /translation="MSTTPEPEPGAPRPALFFDDPLDQQSPDDTDRGWGERPEGDSAAD FT LKRFLDEKPPHHL" FT CDS 149181..150503 FT /transl_table=11 FT /gene="SCO3192" FT /gene_synonym="SCE22.09" FT /product="putative integral membrane protein" FT /note="SCE22.09, possible integral membrane protein, len: FT 440 aa; similar to TR:AAF10839 (EMBL:AE001974) Deinococcus FT radiodurans conserved hypothetical protein DR1273, 429 aa; FT fasta scores: opt: 365 z-score: 385.0 E(): 5.5e-14; 28.6% FT identity in 413 aa overlap. High content in alanine amino FT acid residues. Contains possible hydrophobic membrane FT spanning regions" FT /db_xref="InterPro:IPR010640" FT /db_xref="UniProtKB/TrEMBL:Q9KYV3" FT /protein_id="CAB90976.1" FT /translation="MDDVPCAPPAPAKRGARKHVRAPSAVLGAMMSSPSSASAPSGPPP FT DGHPPVRRLKARHRHESHRAATPLELFFDLCFVVAIAQAGVQLVHAVAEGHAGEGVLNY FT AMVFFAIWWAWMNFTWFASAYDNDDVLYRVVTLVQIAGVLVLAAGVSRAFEDHDWVAVV FT IGYLIMRVAMAAQWLRAGRSAAPPESTMARSYSVGVLLCQIGWLGILFLPEDDRGWLFL FT VMVVLELCVPAYAERKHPSSWHPHHIAERYGLLTIIVLGETIAAATVAVKSGIEENDAL FT GEVLPIAAGGLLIVFAAWWIYFVVPVHSYLRSSRQSFLWGYGHYLVFASAAAIGAGLEV FT TVEQAVGKAHISAVAAAAAVTLPTAVFLLTVWALHARHFKVGIAEQLVLPTAALLVLGC FT TFLGAEAVLVAGIVLALTVAAGVALTARRTERERRAAAPAV" FT CDS 150664..151710 FT /transl_table=11 FT /gene="SCO3193" FT /gene_synonym="SCE22.10" FT /product="conserved hypothetical protein SCE22.10" FT /note="SCE22.10, hypothetical protein, len: 348 aa; similar FT to SW:Y03I_MYCLE (EMBL:U00014) Mycobacterium leprae FT hypothetical 36.1 kD protein B1549_C2_208, 362 aa; fasta FT scores: opt: 894 z-score: 899.8 E(): 0; 48.2% identity in FT 365 aa overlap" FT /db_xref="HSSP:1B65" FT /db_xref="InterPro:IPR005321" FT /db_xref="UniProtKB/TrEMBL:Q9KYV2" FT /protein_id="CAB90977.1" FT /translation="MTVDALTDVAGLLVGHATRTGDGWLTGTTVVLAPEGGAVAGVDVR FT GGGPGTKETDALDPRNLVQKVQAVVLTGGSAYGLDAASGVMAWLEERGRGVRVGPDPAH FT VVPVVPAACVFDLGRGGDFRARPDAVTGYAAVAAAHASAPGAAVAEGCVGAGTGAVVGA FT LKGGVGTASTVLDSGITVAALVVANAAGSVTDPETGVLYGELFRGGRVEYPAPEVHEAA FT GRRLAEVAARNAPPPLNTTLAVVATDAGLSKAQAQKLAGTAHDGIARAVRPVHLLSDGD FT TVFALATGVRPLDAGQPLALNEVLAAGADVVTRAIVRAVRAAEPVDGPGGAWPSYGGLY FT GGPDGREV" FT RBS 151861..151864 FT CDS 151871..153094 FT /transl_table=11 FT /gene="SCO3194" FT /gene_synonym="SCE22.11" FT /product="putative lipoprotein" FT /note="SCE22.11, possible lipoprotein, len: 407 aa; similar FT to TR:CAB76012 (EMBL:AL157916) Streptomyces coelicolor FT putative lipoprotein SC3D11.15, 400 aa; fasta scores: opt: FT 1416 z-score: 1518.4 E(): 0; 52.4% identity in 403 aa FT overlap. Contains correctly situated match to Prosite entry FT PS00013 Prokaryotic membrane lipoprotein lipid attachment FT site and possible N-terminal domain signal peptide FT sequence" FT /db_xref="InterPro:IPR005490" FT /db_xref="UniProtKB/TrEMBL:Q9KYV1" FT /protein_id="CAB90978.1" FT /translation="MTTPDIAKRRVLGACAALVVGALTLTACGGSASADDKQDGKGGAG FT SADTSVAKLVISAKDGSTGASINSTGVKVSDGKLTDVKMTVAESGAAVPGAVSGDGGSW FT KPKGQLERGTKYRITARAKDADGRTAAADSVFTTVSSDNSFVGTYTPDGGSTVGVGMPV FT SFTFDKAITDRKSVQSHISVTSSSGQEVVGHWFGGQRLDFRPEEYWKAGSKVTMKIDLD FT GVEGANGLYGVQKKTVSFTVGRAQVSTVDANTQTMTVVRDGKTLKSVPISAGSAANPTY FT NGQMVISEKSEQTRMNGSTVGFGGEYDIPDVPHAMRLSQSGTFIHGNYWYNRGNPPFGA FT QGTSHGCVGLADAQGAQGDTPGKWFYDNSLVGDVVVVKNSPDDTVAPDNGLNGWNMPWS FT EWTAQSAA" FT misc_feature 151922..151954 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS 153319..153325 FT CDS 153332..154012 FT /transl_table=11 FT /gene="SCO3195" FT /gene_synonym="SCE22.12" FT /product="hypothetical protein SCE22.12" FT /note="SCE22.12, unknown, len: 226 aa" FT /db_xref="UniProtKB/TrEMBL:Q9KYV0" FT /protein_id="CAB90979.1" FT /translation="MRLLGRALNSFELPDETIRLLDCALAHDGSLHSAHHSAGLHRETY FT RHTWLLADGSALTLWELVHNTAPGSEPQHEVYLDEEELRAAGSRLALPPEAPDFELPVQ FT VQLSPVPAPRHAYVPDASADHARRLLRRAENADRPDADLAARLSTACGHQITQAFGGPG FT RAGRARVGFSLYEHAFLLRDGVEVSLWEVEHTATPDGRHMCEVYDSEDTARRAMERRAA FT QVSP" FT CDS complement(154047..156146) FT /transl_table=11 FT /gene="SCO3196" FT /gene_synonym="SCE22.13c" FT /product="putative fructose-specific permease" FT /note="SCE22.13c, probable fructose-specific permease, len: FT 699 aa; similar to SW:PTFB_ECOLI (EMBL:M23196) Escherichia FT coli PTS system, fructose-specific IIBC component FT (EIIBC-fru) FruA 563 aa; fasta scores: opt: 1006 z-score: FT 1038.9 E(): 0; 43.7% identity in 583 aa overlap. Contains FT match to Prosite entry PS00402 Binding-protein-dependent FT transport systems inner membrane comp sign. and possible FT hydrophobic membrane spanning regions in C-terminal domain" FT /db_xref="GOA:Q9KYU9" FT /db_xref="InterPro:IPR006327" FT /db_xref="UniProtKB/TrEMBL:Q9KYU9" FT /protein_id="CAB90980.1" FT /translation="MSDMITADLVDLDLSADTKQAATRALAERMVALGRVTDLEGFLAD FT VAAREAQMPTGLDGGIGIPHCRSGHVTEPTLAFGRSTAGVDFGAADGPADLIFLIAAPA FT GADDAHLTILSSLARRLMNAGFTAALRSLGEPAAAAALIRGEEPTPAADTGEDSTEDVV FT EDTTEETADTGAVSAAASAEAAPGSTGEDSGGPGRPFRIVAVTSCPTGIAHTYMAAESL FT EHAGREAGVEVVVETQGSAGFTRLDPAVIAAADGVILAHDVAVREKGRFAGKPTVDTGV FT KAAINRPGELIGEVRDKAARGEVTSASPGATPVERGGESGEGYGTKLRKWLMSGVSYMV FT PFVAAGGLLIALGFAIGGYEINKAPSVMDHFVWTQADSWAALLFQIGGVAFAFLVPVLA FT GYIAYGMADRPGLVPGFVGGSIALTINAGFLGGLAAGLISGAVVLAIQRVPIPKALRGI FT MPVVVIPLVSAAVVGFLMFVVIGKPIASAQSGMTDWLNGLSGANAVLLGALLGLMMCFD FT LGGPVNKVAYTFATAGIAVASPSDSAMKIMAAVMAAGMVPPLAMALATTVRGRLFNAAE FT RENGKAAWVLGASFISEGAIPFAAADPLRVIPSSMVGGAVTGALSMAFGATLRAPHGGI FT FVVPLIGNPLLYLVAVAAGVCVTTALVIVLKGLRKTVPPAAAQGPGGGADPSSRAPGAK FT QAVAA" FT misc_feature complement(155985..156071) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT RBS complement(156153..156157) FT CDS complement(156274..157221) FT /transl_table=11 FT /gene="SCO3197" FT /gene_synonym="SCE22.14c" FT /product="putative 1-phosphofructokinase" FT /note="SCE22.14c, probable 1-phosphofructokinase, len: 315 FT aa; similar to SW:K1PF_RHOCA (EMBL:X53150) Rhodobacter FT capsulatus 1-phosphofructokinase (EC 2.7.1.56) (fructose FT 1-phosphate kinase) FruK, 316 aa; fasta scores: opt: 555 FT z-score: 576.5 E(): 1.2e-24; 37.8% identity in 315 aa FT overlap. Contains Pfam match to entry PF00294 pfkB, pfkB FT family carbohydrate kinase and match to Prosite entry FT PS00583 pfkB family of carbohydrate kinases signature 1" FT /db_xref="GOA:Q9KYU8" FT /db_xref="InterPro:IPR017583" FT /db_xref="UniProtKB/TrEMBL:Q9KYU8" FT /protein_id="CAB90981.1" FT /translation="MILTVTPNPSLDRTYEVPSLDRGEVVRATGERVDPGGKGVNVSRA FT VTAAGRRTVAVLPLGGAPGALVADLLDAQGIEVAPVPITGPTRSNIALAEADGVLTKIN FT APGPELTPDERELLLETVRRQSPGADWIACCGSLPRGLAPSWYADLVARAHAAGVRIAL FT DTSGPALLRALRERPDVVKPNAEELAEAVGRPLATVGDAVKAAEELRELGARSVLASLG FT ADGQLLVDDAGTWFGTARVDAVRSNVGAGDSSLAGFLVAGGTGPGALASAVAHGAAAVQ FT LPGSVMPTPHDLDPAAVTVTAEVPVDRVLGEPAP" FT misc_feature complement(156451..157116) FT /note="Pfam match to entry PF00294 pfkB, pfkB family FT carbohydrate kinase, score 89.40, E-value 4e-27" FT misc_feature complement(157042..157116) FT /note="PS00583 pfkB family of carbohydrate kinases FT signature 1" FT CDS complement(157218..157979) FT /transl_table=11 FT /gene="SCO3198" FT /gene_synonym="SCE22.15c" FT /product="putative deoR-family transcriptional regulator" FT /note="SCE22.15c, probable deoR-family transcriptional FT regulator, len: 253 aa; similar to TR:Q9X9X5 FT (EMBL:AL096743) Streptomyces coelicolor putative FT transcriptional regulator SCI7.15, 258 aa; fasta scores: FT opt: 609 z-score: 704.8 E(): 8.5e-32; 43.1% identity in 248 FT aa overlap and to SW:GATR_ECOLI (EMBL:AE000298) Escherichia FT coli galactitol utilization operon repressor GatR, 259 aa; FT fasta scores: opt: 438 z-score: 509.7 E(): 6.3e-21; 33.6% FT identity in 256 aa overlap. Contains Pfam match to entry FT PF00455 deoR, Bacterial regulatory proteins, deoR family" FT /db_xref="GOA:Q9KYU7" FT /db_xref="InterPro:IPR001034" FT /db_xref="UniProtKB/TrEMBL:Q9KYU7" FT /protein_id="CAB90982.1" FT /translation="MYAPERQQEILRLARDGGRVDVVSLAEEFQVTAETIRRDLKALDR FT AGLLRRVHGGAIPAGRLDFEPDLAERESTAADEKDRIARAALAELPAEGTLILDAGSTV FT ARMAAAIPPDASLTVVTHSLPIAARLADHPGIQLHIVGGRVRHRTRAAVDAWALRAYGE FT IRADVAVVAANGFSVEHGLTTPDLAEAAVKRAALTAARRVVLLADSSKYAQEHFARFGA FT LGDVDLLITDQGLTPEDAGDIERAGTEVVRA" FT misc_feature complement(157284..157964) FT /note="Pfam match to entry PF00455 deoR, Bacterial FT regulatory proteins, deoR family, score 211.50, E-value FT 1.2e-59" FT CDS complement(158190..159707) FT /transl_table=11 FT /gene="SCO3199" FT /gene_synonym="SCE22.16c" FT /product="putative transmembrane efflux protein" FT /note="SCE22.16c, probable transmembrane efflux protein, FT len: 505 aa; similar to SW:AC22_STRCO (EMBL:M64683) FT Streptomyces coelicolor probable actinorhodin transporter FT ActII-2, 578 aa; fasta scores: opt: 1347 z-score: 1470.8 FT E(): 0; 45.9% identity in 442 aa overlap. Contains Pfam FT match to entry PF00083 sugar_tr, Sugar (and other) FT transporter and also possible hydrophobic membrane spanning FT regions" FT /db_xref="GOA:Q9KYU6" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9KYU6" FT /protein_id="CAB90983.1" FT /translation="MTFKQTPQPAPVPPAAGDRRRWFALAIVMTAAFMDLVDVTIVNIA FT IPSIQRDEGASFSQIQWITAGYALAFAAGLITGGRLGDIHGRKRVFLVGIGGFTLASAL FT CGLAANPEMLVASRILQGGMAALMVPQVLSIVHATFPAHERGKVFGLFGAIVGLGAVSG FT PLLGALLTEWNLFGLEWRPIFLINLPVGIAGLVLGSRFITESKAPRALRLDLVGVALVT FT LGLLMLIYPLTRGEELGWPLWGYLSMAGSLVVLAVLVAYERRKSARDGSPLVELSLFRV FT KSFAAGIAVQTVFGVALGVFFLVWTLYMQFGLGWSPLRAGLTGVPFSIAVSTAAGISVQ FT TLVPRFGRKVLQTGALVMAAGVLLYMGESGRYGLAITSWQMALPLVVMGLGMGLIVAPL FT TDAVLSQVPREHAGAASGLINTVQQMGNALGLGLVSVVFFGTMSDRLTPDRIGPAYVDA FT FQNALGWVAAVMAVIFLLMFALPRRPAQHVEGGPAEDSAQEQEPALV" FT misc_feature complement(158232..159641) FT /note="Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter, score -100.00, E-value 0.0027" FT CDS 159770..160741 FT /transl_table=11 FT /gene="SCO3200" FT /gene_synonym="SCE22.17" FT /product="putative deoR-family transcriptional regulator" FT /note="SCE22.17, probable deoR-family transcriptional FT regulator, len: 330 aa; similar to TR:CAB81864 FT (EMBL:AL161691) Streptomyces coelicolor putative FT deoR-family transcriptional regulator SCD40A.19c, 339 aa; FT fasta scores: opt: 682 z-score: 765.6 E(): 0; 43.3% FT identity in 298 aa overlap and to Streptomyces coelicolor FT SC8G12.03c, 343 aa; fasta scores: opt: 761 z-score: 720.8 FT E(): 1.3e-34; 45.1% identity in 326 aa overlap. Contains FT match to Prosite entry PS00894 Bacterial regulatory FT proteins, deoR family signature and possible FT helix-turn-helix motif at residues 22..43 (+5.48 SD)" FT /db_xref="GOA:Q9KYU5" FT /db_xref="InterPro:IPR018356" FT /db_xref="UniProtKB/TrEMBL:Q9KYU5" FT /protein_id="CAB90984.1" FT /translation="MTTDTPARLLTLLSLLQTPREWPGGELADRLGVSRRTVRRDIDRL FT RELGYPVQATMGADGGYRLVAGKAMPPLVLDDEEAVAIAVGLRAGAGHAVEGLDEASVR FT ALAKLEQVLPSRLRHRVTTLQSATTPLTSGDGPSIAPETLTVMASTVAGHERLRFAYRA FT ADGTATRRSTEPYRLVSTGRRWYLVAYDLDRDDWRTFRVDRVSEPFATGARFAPRELPT FT GDAAEYLRRSMQRRHESYEITVVFHAPAEAVAPLLPHWMGTPEPVDGCVSCVVRATVSG FT PVEWTAARLATTGLEFRVREPAELVECVRELGARLGRAAEPG" FT misc_feature 159791..159895 FT /note="PS00894 Bacterial regulatory proteins, deoR family FT signature" FT CDS complement(161044..161754) FT /transl_table=11 FT /gene="SCO3201" FT /gene_synonym="SCE22.18c" FT /product="putative tetR-family transcriptional regulator" FT /note="SCE22.18c, probable tetR-family transcriptional FT regulator, len: 236 aa; similar to TR:CAB62751 FT (EMBL:AL133424) Streptomyces coelicolor putative FT tetR-family transcriptional regulator SCF56.06, 213 aa; FT fasta scores: opt: 311 z-score: 346.2 E(): 8e-12; 38.1% FT identity in 194 aa overlap and to SW:TCMR_STRGA FT (EMBL:M80674) Streptomyces glaucescens tetracenomycin C FT transcriptional repressor TcmR, 226 aa; fasta scores: opt: FT 254 z-score: 284.8 E(): 2.1e-08; 32.2% identity in 214 aa FT overlap. Contains Pfam match to entry PF00440 tetR, FT Bacterial regulatory proteins, tetR family and possible FT helix-turn-helix motif at residues 53..74 (+5.22 SD)" FT /db_xref="GOA:Q9KYU4" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9KYU4" FT /protein_id="CAB90985.1" FT /translation="MSSTIPALPGPEPGPGPGPAGPVSLTERRKAETRMEIARAAARLF FT VGQGLRATRAEDIARAAGVAPRTFYRYFATKEEAVAPLYALGAERWVRAVREAPAELSP FT PEALERAVRHTLTPGAGVSAPSWEWARTLIRLAESSPALRKVWAEVCHSTERGLVQALA FT ARMSGGDDNVAVRLAASPRLHFAAAVAGASVRVAAEHWASSSPQGARSPLEQALLNLEV FT LRGFAWEAGPAEEG" FT misc_feature complement(161521..161646) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 38.40, E-value FT 6.4e-09" FT misc_feature complement(161872..163263) FT /note="previously sequenced fragment EBML:X52982 FT Streptomyces coelicolor hrdD gene for principal sigma FT factor" FT CDS complement(162181..163179) FT /transl_table=11 FT /gene="SCO3202" FT /gene_synonym="hrdD" FT /gene_synonym="SCE22.19c" FT /product="RNA polymerase principal sigma factor" FT /note="SCE22.19c, hrdD, RNA polymerase principal sigma FT factor, len: 332 aa; identical to previously sequenced FT SW:HRDD_STRCO (EMBL:X52982) Streptomyces coelicolor RNA FT polymerase principal sigma factor HrdD, 332 aa. Contains FT Pfam match to entry PF00140 sigma70, Sigma-70 factor and FT matches to Prosite entries PS00715 Sigma-70 factors family FT signature 1 and PS00716 Sigma-70 factors family signature FT 2. Contains also possible helix-turn-helix motif at FT residues 292..313 (+5.89 SD)" FT /db_xref="GOA:P18249" FT /db_xref="HSSP:1KU3" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/Swiss-Prot:P18249" FT /protein_id="CAB90986.1" FT /translation="MATRAVARRKSAAGETSGSATSVRANGGELADRDLVGMYLDEIAR FT TPLLDAAKEVELSQTIEAGVFARQVLEGYEETGADATREELQALIDESERAKDVFIRSN FT LRLVVAVARRYPRSGLPLLDLIQEGNAGLVRAVEKFDYRKGFKFSTYATWWIRQAITRS FT IADQSRTIRLPVHLVEELGRIRRVQREFNREHGREPEPAEIAAELGSTPERVTDVLDWA FT RDPVSLNMSVDDEGETQFGDLLEDTSAVSPEQSVLTLLRSEELDDLIGRLDPRTASIIK FT MRYGIDDGRERTLTEVGKEHGLTRERIRQIEKHALLELKKLARDTGFEAAA" FT misc_feature complement(162217..162900) FT /note="Pfam match to entry PF00140 sigma70, Sigma-70 FT factor, score 421.20, E-value 9.8e-123" FT misc_feature complement(162223..162303) FT /note="PS00716 Sigma-70 factors family signature 2" FT misc_feature complement(162769..162810) FT /note="PS00715 Sigma-70 factors family signature 1" FT RBS complement(163185..163188) FT misc_feature 163229..164018 FT /note="previously sequenced fragment EMBL:M62753 FT S.coelicolor bar gene, complete cds." FT RBS 163383..163387 FT CDS 163395..163910 FT /transl_table=11 FT /gene="SCO3203" FT /gene_synonym="bar" FT /gene_synonym="SCE22.20" FT /product="phosphinothricin acetyltransferase" FT /note="SCE22.20, bar, phosphinothricin acetyltransferase, FT len: 171 aa; identical to previously sequenced SW:BAR_STRCO FT (EMBL:M62753) Streptomyces coelicolor phosphinothricin FT acetyltransferase (EC 2.3.1.-) Bar, 171 aa. Contains Pfam FT match to entry PF00583 Acetyltransf, Acetyltransferase FT (GNAT) family" FT /db_xref="GOA:P21861" FT /db_xref="InterPro:IPR000182" FT /db_xref="UniProtKB/Swiss-Prot:P21861" FT /protein_id="CAB90987.1" FT /translation="MPGTAEVQVRPGVEEDLKPLTDLYNHYVRETPITFDTEPFTPEER FT RPWLLSHPEDGPYRLRVATDAESQEILGYATSSPYRAKPAYATSVETTVYVAPGAGGRG FT IGSLLYASLFDALAAEDLHRAYAGIAQPNEASARLHARFGFRHVGTYREVGRKFGRYWD FT VAWYERPL" FT misc_feature 163419..163832 FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 44.00, E-value FT 3.5e-09" FT CDS complement(163943..164704) FT /transl_table=11 FT /gene="SCO3204" FT /gene_synonym="SCE22.21c" FT /product="hypothetical protein SCE22.21c" FT /note="SCE22.21c, unknown, len: 253 aa; identical to FT previously sequenced TR:Q54224 (EMBL:X79980) Streptomyces FT griseus unknown gene, 253 aa and similar to SW:YGID_ECOLI FT (EMBL:M77129) Escherichia coli hypothetical 29.9 kD protein FT in TolC-RibB intergenic region (ORFC) YgiD, 271 aa; fasta FT scores: opt: 566 z-score: 655.8 E(): 4.6e-29; 38.5% FT identity in 262 aa overlap" FT /db_xref="GOA:Q9KYU2" FT /db_xref="InterPro:IPR004183" FT /db_xref="UniProtKB/TrEMBL:Q9KYU2" FT /protein_id="CAB90988.1" FT /translation="MPALYLSHGAPPLADDPVWPGELAAWAADLPRPKAILVVSAHWEE FT APLALGATRTVPLVYDFWGFPEHYYQVRYGAPGAPALAESVRKLLRAPGTPVQDVPDRG FT LDHGAYVPLVEMYPGADIPVLQVSMPTLDPARLMEIGRRLAPLRDEGVLIVGSGFFTHN FT LAALRQGGIPSWSAEFDDWGRRALEGGDVDGLLDFAHKSPAGRLAHPRTEHFAPLFVTM FT GAADAAGELDLRRSVIDGFWMGLAKRSVQFG" FT RBS complement(164708..164711) FT CDS 164824..165315 FT /transl_table=11 FT /gene="SCO3205" FT /gene_synonym="SCE22.22" FT /product="putative MarR-family transcriptional repressor" FT /note="SCE22.22, probable MarR-family transcriptional FT repressor, len: 163 aa; similar to TR:Q9X5U1 FT (EMBL:AF127374) Streptomyces lavendula repressor MmcW, 163 FT aa; fasta scores: opt: 724 z-score: 892.8 E(): 0; 65.4% FT identity in 162 aa overlap and to TR:CAB70635 FT (EMBL:AL137242) Streptomyces coelicolor putative FT transcriptional regulator SC8F4.09c, 158 aa; fasta scores: FT opt: 409 z-score: 459.2 E(): 4.8e-20; 43.2% identity in 146 FT aa overlap. Contains Pfam match to entry PF01047 MarR, MarR FT family" FT /db_xref="GOA:Q9KYU1" FT /db_xref="InterPro:IPR000835" FT /db_xref="UniProtKB/TrEMBL:Q9KYU1" FT /protein_id="CAB90989.1" FT /translation="MNDEPRWLTAEEQLVWRSYIEAATLLEDHLDRQLQRDAGMPHVYY FT GLLVKLAESPRRRLRMTELAKYAKITRSRLSHAVARLEKNGWVRREDCPSDKRGQFAIL FT TDEGYEVLRRTAPGHVDAVRQAVFDRLTPEQQKSLGEIMRIVAEGLQPSEAGADLPWLR FT " FT misc_feature 164941..165261 FT /note="Pfam match to entry PF01047 MarR, MarR family, score FT 71.20, E-value 2.2e-17" FT CDS complement(165416..166960) FT /transl_table=11 FT /gene="SCO3206" FT /gene_synonym="SCE22.23c" FT /product="putative transmembrane efflux protein" FT /note="SCE22.23c, probable transmembrane efflux protein, FT len: 514 aa; similar to SW:PUR8_STRLP (EMBL:X76855) FT Streptomyces lipmanii puromycin resistance protein Pur8, FT 503 aa; fasta scores: opt: 1634 z-score: 1768.4 E(): 0; FT 53.1% identity in 493 aa overlap and to many other efflux FT proteins, e.g. TR:CAA18346 (EMBL:AL022268) Streptomyces FT coelicolor transmembrane efflux protein SC4H2.31c, 515 aa; FT fasta scores: opt: 1237 z-score: 1139.7 E(): 0; 41.0% FT identity in 493 aa overlap. Contains match to Prosite entry FT PS00216 Sugar transport proteins signature 1 and possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9KYU0" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9KYU0" FT /protein_id="CAB90990.1" FT /translation="MSQTAVKASGVSDAPDAGRWKALVFIALAQLMVVLDATIVNIALP FT SAQQDLGISDGNRQWVVTAYALAFGGLLLFGGRIADLWGRKRTFVLGLAGFAVASALGG FT AATNEAMMFGSRALQGVFGALLAPAALSLLAVMFTDAKERAKAFGIYGAIAGGGGAVGL FT ILGGFLTEYLNWRWTFFVNIPFAIVAAAGAYLVIREPKGGRNRSPLDIPGVILSTLGLV FT ALVYGFTRAESNGWSDAVTVGMFVGSAVLLLAFVLVEARVKAPLLPLRVITERNRGGIY FT LSLGLAIIAMFGLFLFLTYYLQIVKGYTPVKTGFAFLPMIAGMITGSTQIGARLMTRVA FT PRLLMGPGFLVAAVGMLFLTQLEVDTSYAGVLLPGMLLLGLGMGTAFMPAMSMATMGVE FT ARDAGVASAMVNTSQQVGGAIGTALLNTIAASATTSYIADHMGGAASRSQQQLVQLEGQ FT VQGYTSAIWFAVGILVVAAAIALTLINAGRPGGGAVTGSGAGDEAEDELRVPVVAH" FT misc_feature complement(166685..166735) FT /note="PS00216 Sugar transport proteins signature 1" FT CDS complement(167102..>167836) FT /transl_table=11 FT /gene="SCO3207" FT /gene_synonym="SCE22.24c" FT /product="putative tetR-family transcriptional regulator FT (fragment)" FT /note="SCE22.24c, probable tetR-family transcriptional FT regulator (fragment), len: >244 aa; similar to TR:Q9WX19 FT (EMBL:AL079345) Streptomyces coelicolor putative FT transcriptional regulator SCE68.13, 230 aa; fasta scores: FT opt: 305 z-score: 361.2 E(): 1.2e-12; 35.2% identity in 210 FT aa overlap. Contains Pfam match to entry PF00440 tetR, FT Bacterial regulatory proteins, tetR family. Contains also FT possible helix-turn-helix motif at residues 67..88 (+4.22 FT SD)" FT /db_xref="GOA:Q9KYT9" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9KYT9" FT /protein_id="CAB90991.1" FT /translation="FPPRIVNPVVTPVTDTLTDTTDTKEYAVQTAIPDQRKVARPRADA FT LRNRERIVLAAREMFVEHGPDVPLDDVARRAGVGNATVYRNFPDRDALVREVVCSVMDR FT TARAAELALAETGDAFEALERFVHASADERISALCPMVASTFDQHHPDLEAARGRVERL FT VAEVMDRAKAAGQLRGDVGVGDLMIAAAQLSRPPAGTGCVNADRFVHRHLQLFLDGLRA FT PARSVLPGAAVTLEDLRRPCDQ" FT misc_feature complement(167546..167683) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 20.80, E-value FT 0.0005" FT CDS 168075..169373 FT /transl_table=11 FT /gene="SCO3208" FT /gene_synonym="SCE8.01" FT /product="putative secreted protein" FT /note="SCE8.01, possible secreted protein, len: 432 aa; FT similar to TR:CAC44281 (EMBL:AL596030) Streptomyces FT coelicolor hypothetical protein SCBAC17F8.09, 436 aa; fasta FT scores: opt: 555 Z-score: 578.7 E(): 1.3e-24; 33.991% FT identity in 456 aa overlap. Contains a possible N-terminal FT signal sequence" FT /db_xref="HSSP:1C7K" FT /db_xref="InterPro:IPR000209" FT /db_xref="UniProtKB/TrEMBL:Q9Z4X3" FT /protein_id="CAB38579.1" FT /translation="MQPPPQAQPPSRRIRPRRPAAAGTVAVLTLALCTSAGTGRLAPGT FT STAGPGPAALSRSSAHGPCMIGGGAEIQMSEGVPTSAGYARSTGTVRALNLMIDFSDAP FT GEGKALDRYAEFFPQTEEWFRTSSYGRLDYRPETPVRDWLRMPKSFAEYGIERGAPFEP FT GYRKLVQDLVAAADSKVDFRSYDLLNVLVTPNAGPSALDTVLSVTFAGNQEAPVADGVP FT VANASFVYSRQDDGSGSYDETGYRVLPHENGHVFGLPDLYTQEGGGAVGHWDIMSEDWG FT ANNDLLGWHKWKLGWLDPSQVHCASAPGTTEYTLTPLARKGGDKLVVLPLSGTSGYAVE FT LRTREGNDETVCRPGVLIYKVDADVDTGMGPVRVYDSRRDSGGCTRSPNVHAELSDAAF FT TPGETFEDPRKGVTIKVSEKDGEGDVRVRVTRR" FT CDS 169433..171007 FT /transl_table=11 FT /gene="SCO3209" FT /gene_synonym="SCE8.02" FT /product="putative transcriptional regulator" FT /note="SCE8.02, possible transcriptional regulator, len: FT 524 aa; N-terminal (up to approx. 270aa) similar to one FT group of transcriptional regulator (eg. SW:ICLR_ECOLI FT acetate operon repressor from Escherichia coli (274 aa) FT fasta scores; opt: 208, z-score: 221.4, E(): 5e-05, (27.1% FT identity in 262 aa overlap)) and C-terminal (from approx. FT 270aa) similar to a different group of transcriptional FT regulator (eg. SW:MHPR_ECOLI mhp operon transcriptional FT activator (315 aa) fasta scores; opt: 205, z-score: 217.5, FT E(): 8.3e-05, (28.5% identity in 267 aa overlap). Both FT halves appear to be members of the same family of FT transcriptional regulators (IclR-type) suggesting a FT duplication event. Contains two probable helix-turn-helix FT motifs at 37-58aa (Score 1082 (+2.87 SD)) and 320-341aa FT (Score 1437 (+4.08 SD))." FT /db_xref="GOA:Q9Z4X2" FT /db_xref="InterPro:IPR005471" FT /db_xref="UniProtKB/TrEMBL:Q9Z4X2" FT /protein_id="CAB38580.1" FT /translation="MPAHTTHDAARDEAVAPLLRGIAVLGRLTGADGGTLSLSALERTT FT GLARSTVDRLTATLARMGYVRLDGRDVVLAPRLMELGNAYLAALRLPALLSARADGLAD FT ELDESVSLAVGDRDGIRFIHQATRRRAMSLSFRIGDLLPAERTAPGPLFAAEWTASDWH FT RWRERRAADPGDHSFPAVPPREPGAPGEDFARRAAKAAADGWALDDQLIEPGLVAVSVP FT VRDPGTGRVACVASVVSHTSRHTAPDLRAALLPRLRAAVAAMEDDLRAAPAPEPGPPPA FT GLALWTGASKQELGREFVESLARGLTVLTAFGEGRSALTLTQVAQATGLARATARRALL FT THARAGLVAPAAGHTFTLTPRVLSLGFPPLSRTSLPEIAQPHLTALAERVHESASLAVL FT ADSGEEIQYTARASAARVLSARVTVGTRLPARATALGRVLLALPEVRARGYALVDEELE FT AGLRAIAVPVRDRTGRVVAALNVALHAARRTADDCVAQILPELRHTADLVETELRVAGR FT FCRVAVV" FT CDS complement(171249..172703) FT /transl_table=11 FT /gene="SCO3210" FT /gene_synonym="SCE8.03c" FT /product="putative 2-dehydro-3-deoxyheptonate aldolase" FT /note="SCE8.03c, aro, probable 2-dehydro-3-deoxyheptonate FT aldolase, len: 484 aa; similar to many e.g. TR:O52308 FT (EMBL:AF035756) 2-dehydro-3-deoxyheptonate aldolase from FT Streptomyces sp. fasta scores; opt: 1619, z-score: 1722.0, FT E(): 0, (54.5% identity in 440 aa overlap) and FT SW:AROF_ARATH phospho-2-dehydro-3-deoxyheptonate aldolase 1 FT from Arabidopsis thaliana (525 aa) fasta scores; opt: 1457, FT z-score: 1549.2, E(): 0, (48.4% identity in 457 aa FT overlap)." FT /db_xref="GOA:Q9Z4X1" FT /db_xref="InterPro:IPR002480" FT /db_xref="UniProtKB/TrEMBL:Q9Z4X1" FT /protein_id="CAB38581.1" FT /translation="MTASDTYTQPRTAPAGTGTAAPGPTGPAADAGRGGWTPGSWRSRP FT AAQQPEWPDPGELRGVEDTLALRPPLVLPDEILDLRRSLAQVAAGEGFLLQAGDCAERF FT GSCTEAGVRGKLRVILQVAILLTYGSGLPVVKVGRIAGQFGKPRSRPTEAVDGVELPVY FT RGDIVNGPEFTAEARRPDAGRLLSAYHHASAALNVLRALTLGGYADLGQVHEWNQEFVR FT RSPAGQRYEKAADDITWALRFMSACGLDTRSQAALHQVQLYTSHEALLPQYEQALIRYD FT EKRRGWFDTSAHLLWIGDRTRRVDGAHVELLAGVDNPVGVKVGPTMGVDDLRELCERLD FT PDRAPGRLVLISRLGAGRGAELLPPLLRAVRDAGHAPVWACDPMHGNTFVSASGYKTRR FT LSDITTEVAEFFAVHREEGLHPGGIHLELTGDDVTECLGGDLDEVLDTHLASRYETACD FT PRLNAAQSIELAFGVARLLRELRGGA" FT CDS complement(172700..173476) FT /transl_table=11 FT /gene="SCO3211" FT /gene_synonym="SCE8.04c" FT /gene_synonym="trpC2" FT /product="putative indoleglycerol phosphate synthase" FT /note="SCE8.04c, trpC2, probable indoleglycerol phosphate FT synthase, len: 258aa; similar to many inluding another from FT Streptomyces coelicolor TR:O68814 (EMBL:AF054585) located FT in the trpCBA locus which maps (by hybridisation) to the FT overlap between cosmids 3A3 and 4G6 (269 aa) fasta scores; FT opt: 652, z-score: 740.9, E(): 0, (47.2% identity in 254 aa FT overlap). Also similar to SW:TRPC_PSEAE trpC, probable FT indoleglycerol phosphate synthase from Pseudomonas FT aeruginosa (278 aa) fasta scores; opt: 632, z-score: 718.3, FT E(): 1.1e-32, (43.5% identity in 260 aa overlap). Contains FT Pfam match to entry PF00218 IGPS, Indole-3-glycerol FT phosphate synthases, score 316.20, E-value 3.8e-91." FT /db_xref="GOA:Q9Z4X0" FT /db_xref="HSSP:1PII" FT /db_xref="InterPro:IPR001468" FT /db_xref="UniProtKB/Swiss-Prot:Q9Z4X0" FT /protein_id="CAB38582.1" FT /translation="MSGILAGLVAEAESQTGRRRALRTEAKLTELAAAAPPARDFAAAL FT REPGLAVIAEMKPRSPSKGPLTDDYRPAELARAYQGGGAHAVSVLTHEAGFGGSPDHLA FT VARAACELPVLRKDFVVDEYQILEARALGADALLLIVAALAPARLAALLARTRACGMEA FT LVEVHDEREVDVALEAGADVIGVNHRDLRDFSIDRTLSARLRGRVGTGRVMVGESGVRG FT APDARALEAAGVDAVLVGELLMRAGDPGTTIKGLVG" FT misc_feature complement(172709..173374) FT /note="Pfam match to entry PF00218 IGPS, Indole-3-glycerol FT phosphate synthases, score 316.20, E-value 3.8e-91." FT CDS complement(173473..174480) FT /transl_table=11 FT /gene="SCO3212" FT /gene_synonym="SCE8.05c" FT /gene_synonym="trpD2" FT /product="probable anthranilate phosphoribotransferase" FT /note="SCE8.05c, trpD2, anthranilate FT phosphoribotransferase, len: 335 aa; similar to many e.g. FT SW:TRPD_AZOBR TrpD, anthranilate phosphoribotransferase FT from Azospirillum brasilense (355 aa) fasta scores; opt: FT 924, z-score: 1056.6, E(): 0, (49.5% identity in 315 aa FT overlap). Contains Pfam match to entry PF00591 FT Glycos_transf_3, glycosyl transferase family, score 223.70, FT E-value 2.8e-63." FT /db_xref="GOA:Q9Z4W9" FT /db_xref="HSSP:1KHD" FT /db_xref="InterPro:IPR017459" FT /db_xref="UniProtKB/Swiss-Prot:Q9Z4W9" FT /protein_id="CAB38583.1" FT /translation="MQRPLTEAEAADAMRVIMRGEATAAQIAAFALAVTVRGASADNLA FT GMARAAQEFATPVPRAGGDLLDTCGTGGDGLNTFNISTAAAIVAAACGVRVAKHGNRSA FT SSACGSADVLEELGVRIDLGAEEAAACLDRTGITFLFAPVFHPAFRHTAGPRRELGART FT VFNLLGPLCNPSGARLRTLGVPSRELVEPMTEVLERLGVTRALVFHSADGMDELSTAAP FT AHLVELRDGRRTTHRFDPAEHGLARSRPGDLAGGDRAVNAAVLRRVLAGGRGPARDVVL FT LNAAAALRVAGVAGTWSDGLRLAASAVDGGAAAGLLDRWAHASWQRADLVEVPA" FT misc_feature complement(174052..174477) FT /note="Pfam match to entry PF00591 Glycos_transf_3, FT glycosyl transferase family, score 223.70, E-value FT 2.8e-63." FT CDS complement(174497..175099) FT /transl_table=11 FT /gene="SCO3213" FT /gene_synonym="SCE8.06c" FT /gene_synonym="trpG" FT /product="probable anthranilate synthase component II" FT /note="SCE8.06c, trpG, anthranilate synthase component II, FT len: 200aa; similar to many eg. TR:G4185545 (EMBL:AF108766) FT TrpG, anthranilate synthase component II, from Rhodobacter FT sphaeroides (195 aa) fasta scores; opt: 728, z-score: FT 825.0, E(): 0, (60.2% identity in 186 aa overlap). Contains FT matches to Pfam entry PF00117 GATase, Glutamine FT amidotransferases class-I, score 332.60, E-value 4.3e-96 FT and Prosite PS00442 Glutamine amidotransferases class-I FT active site." FT /db_xref="GOA:Q9Z4W8" FT /db_xref="HSSP:1I1Q" FT /db_xref="InterPro:IPR006221" FT /db_xref="UniProtKB/TrEMBL:Q9Z4W8" FT /protein_id="CAB38584.1" FT /translation="MSAPTGTRAGAAPRVAVIDNYDSFTYNLVHYVAELGGRPTVFRND FT AVTVAELAGFDLLLLSPGPGTPAGAGICVDAVRALGARLPVLGVCLGHQAVAVAYGGSV FT VRGEQVHGKASAVHHDGGGVFAGLPDPFSATRYHSLVVEPAGLPDELTVTARTADGTVM FT GLRHRTHPVHGVQFHPESVLSPEGKQLIANFLECADD" FT misc_feature complement(174509..175060) FT /note="Pfam match to entry PF00117 GATase, Glutamine FT amidotransferases class-I, score 332.60, E-value 4.3e-96" FT misc_feature complement(174812..174847) FT /note="PS00442 Glutamine amidotransferases class-I active FT site." FT CDS complement(175096..176631) FT /transl_table=11 FT /gene="SCO3214" FT /gene_synonym="SCE8.07c" FT /gene_synonym="trpE2" FT /product="probable anthranilate synthase component I" FT /note="SCE8.07c, trpE2, anthranilate synthase component I, FT len: 511aa; similar to many eg. SW:TRPE_PSEPU TrpE, FT anthranilate synthase component I from Pseudomonas putida FT (493 aa) fasta scores; opt: 1173, z-score: 1253.8, E(): 0, FT (44.3% identity in 492 aa overlap). Contains Pfam match to FT entry PF00425 chorismate_bind, chorismate binding enzyme, FT score 529.40, E-value 2.5e-155." FT /db_xref="GOA:Q9Z4W7" FT /db_xref="HSSP:1K0E" FT /db_xref="InterPro:IPR015890" FT /db_xref="UniProtKB/Swiss-Prot:Q9Z4W7" FT /protein_id="CAB38585.1" FT /translation="MTTHAAEAPTTDPQGAPGSQKTPDATEAEEAARATVPHRAAAAAL FT AREHDVVPLHQEFLDDSVSPVTAFAQLCGPDEAGFLLESVPVSGGVARYSYVGHRPVPL FT EPTGGDPLTALRSHLARSVAPVPGLPPFHGGVVGYLGYEAARHFEDLPLAAGPPPGLPE FT SAFLAADDLVVFDHATRRVLLMTLYRPARESYDDAVARIVRLNRALRRAPAPAAFSGRP FT LAAATPADHGTQGWTANLTEAQFTERVARAREHIAAGDAFQIVLSRRLSRPLRARPTDL FT YRHLRATNPSPYMYHLSLGGGRHVIGASPELLVKAEGRTVRTRPLAGTRPRHPDPAEDL FT RLERELRADEKERAEHVMLVDLGRNDLGRVTEPGTVRVERLMRVERFSHVMHLSSTVRG FT RLAEGRDALDALRSAFPAGTLSGAPKIRAMEIIAELEPEQRGVYGGALGFVGADGLTDF FT AIALRTMVVADGHVHVQAGAGIVADSDPAAEFRETLHKSRAMLTAVRRAEAAA" FT misc_feature complement(175120..175911) FT /note="Pfam match to entry PF00425 chorismate_bind, FT chorismate binding enzyme, score 529.40, E-value 2.5e-155" FT CDS complement(176628..177644) FT /transl_table=11 FT /gene="SCO3215" FT /gene_synonym="SCE8.08c" FT /product="hypothetical protein" FT /note="SCE8.08c, unknown, len: 338 aa" FT /db_xref="GOA:Q9Z4W6" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:Q9Z4W6" FT /protein_id="CAB38586.1" FT /translation="MTGDDVQGQLAELRRSHPELHALADPRRIAAWEAARGSAPGRHDD FT FGADGEGSRGVEYVQAQALNRRARETGIRKLLGFAETARRTAAGDRPVLVDLLGGDGLV FT RKVCEELGIGDFNILTCDASPHMVTTAWAAGVPALLQRAEQPLLRDHSVDAVLLAYGSH FT HVPSSDRQTVATEARRMLRPGGTFVLHDFLVGSPVDVWFEEVTDVYSATGHKFLHFTRD FT EIEGYLEKAGYDHREVVEIDDPYTAVAATPEEAELEIGRYLLNMYGLVKVFEGRTEQEA FT YRWVAETAKAVFRYPDAEGGLASSELRQEGTGGWRVTIPRRAVVGVGRVSATAGKAA" FT CDS 177937..180327 FT /transl_table=11 FT /gene="SCO3216" FT /gene_synonym="SCE8.09" FT /product="putative integral membrane ATPase" FT /note="SCE8.09, probable integral membrane ATPase, len: 796 FT aa; member of a large family including SW:Y1B2_MYCTU FT putative cation-transporting ATPase from Mycobacterium FT tuberculosis (797 aa) fasta scores; opt: 2741, z-score: FT 2896.9, E(): 0, (56.8% identity in 791 aa overlap). FT Contains two Pfam matches to entry PF00122 E1-E2_ATPase, FT E1-E2 ATPases, score 109.40, E-value 9.7e-30 and score FT 155.80, E-value 7.3e-43, and Prosite match to PS00154 E1-E2 FT ATPases phosphorylation site." FT /db_xref="GOA:Q9Z4W5" FT /db_xref="InterPro:IPR008250" FT /db_xref="UniProtKB/TrEMBL:Q9Z4W5" FT /protein_id="CAB38587.1" FT /translation="MKNQLDEPGGAVRVGGGGGLSAAEVAERVAAGQVNDVPARSSRTI FT GEIVRSNLFTRINAIIGVLFVIVMIVGPVQDGLFGGVILANTAIGIIQEVRAKRTLDQL FT AIVGESRPRVWRDGQRLELSASEIVIDDSIDLGQGDKIVVDGTVTSGDSLEVDESLLTG FT EADPVVKQPGDPVMSGSFVVAGSGTFTATRVGKEAYASQLADEARRFSLVNSELRNGID FT RILKFVTYAIVPAGIALIITQFVVNDDNFSEAIRRMVGGLVPMVPEGLVLLTSLAFAVG FT VVRLGKKQCLVQELPAIEGLARVDTVCLDKTGTLTEASMDVDEVLPLLPELPVDAVLGA FT LGAADERPNASLQAIIESYPAPEGWRRTATAPFSSARRWSGASFAEPSGTESAWLLGAP FT DTMLPAGHSVLTAADSYGARGLRVLLLARSDRPLDTLMDDPAAVPAAVTAAALVVIKQR FT VRPEARATLDYFADQGVTAKVISGDNAVSVGAVASSLSLPGAERPVDARFLPDEPAELA FT DAVEENTVFGRVGPQQKRDMVGALQSRGHTVAMTGDGVNDVLALKDADIGVGMGSGSPA FT TRAVAQIVLLNNNFSALPSVVAEGRRVIGNIERVANLFLTKTVYSVLMALVVVIAQVPY FT PFLPRHITLVGSLTIGIPAFFLALAPNKERARSNFVGRVLRFAIPAGALAAAATSVAYL FT IARSVYDDNLDAETSAATLALFLTALWALAVIARPYTWWRVLLVLTMAVGFAVVLVVPY FT LQEFFQLKLVGVTAPWAAVACAAVAGLVLELVWARMRRRLDAD" FT misc_feature 178165..178920 FT /note="Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 FT ATPases, score 155.80, E-value 7.3e-43" FT misc_feature 178864..178884 FT /note="PS00154 E1-E2 ATPases phosphorylation site." FT misc_feature 179311..179919 FT /note="Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 FT ATPases, score 109.40, E-value 9.7e-30" FT CDS 181072..182988 FT /transl_table=11 FT /gene="SCO3217" FT /gene_synonym="SCE8.10" FT /gene_synonym="cdaR" FT /product="putative transcriptional regulator" FT /note="SCE8.10, cdaR, transcriptional activator protein, FT len: 638 aa; Previously sequenced and therefore identical FT to CdaR (EM:AF124138) transcriptional activator protein for FT the CDA biosynthesis cluster in Streptomyces coelicolor. FT Also similar to many including SW:AFSR_STRCO AfsR, a global FT regulatory protein for secondary metabolite formation in FT Streptomyces coelicolor A3(2) (993 aa) fasta scores; opt: FT 972, z-score: 1087.1, E(): 0, (36.6% identity in 610 aa FT overlap) and SW:REDD_STRCO regulator of undecylprodigiosin FT production in Streptomyces coelicolor A3(2) (350 aa) fasta FT scores; opt: 382, z-score: 432.2, E(): 9.1e-17, (32.6% FT identity in 258 aa overlap). Contains match to PS00017 FT ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q9Z389" FT /db_xref="InterPro:IPR000767" FT /db_xref="UniProtKB/TrEMBL:Q9Z389" FT /protein_id="CAB38588.1" FT /translation="MDLRLIEPIYQRIGNAEVSQKETPTAGLEFGVLGPLEVHMNGRGL FT TVGGPRQRAVLSALLLSANQVVSFDSLIEEVWNGRPPSTARTQVAICIATLRKIFRTAG FT WEQETIITATPGYMLSLAGHSLDSLRFEQLVSRATELTADERPAPAAEALRQALALWRG FT PALGGVHAPFAETEAARLDEQRMLAVEQHMALRLQLGEHQSVLGELQALVGACPLRDRL FT RYYLMLAQYRSGRRAEALTTFRDGMRYSIEEIGLELGTDLQSLHDSILRDEFPQLGVLG FT IAAARKDRQQTVPSQLPESDAYFIGRSREQWLMDDVLLDGSAQNPPAIAYLTGSPGIGK FT TSLAVNWAHRAAHRFPDGQLFADLREGGPLEVLHQFLRQLGDEGPLPAEPAEAAERYRG FT LLEGRRVLIVLDHASSYAQVRHLLPTSGGCCVLITGRANLDELMQKYRTFRLRVAPLSD FT DEARETLAGVLRDSRAQDVPEATSRLAALCGHSPLALRAAAARLLTKTHWRVLDLVCRL FT ERSGDRLTALSIGEDSLRARLDRSMRELDPRVAFAYRELSRLGDADFDAEQAAQVLGTD FT LLEAEDLIETLVDAQLLEAVGRSRWGGMRFKWQELVRLHASHCLTAAGSLETPAPVAVA FT LTD" FT misc_feature 182071..182094 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS complement(183050..183265) FT /transl_table=11 FT /gene="SCO3218" FT /gene_synonym="SCE8.11c" FT /product="putative small conserved hypothetical protein" FT /note="SCE8.11c, small conserved hypothetical protein, len: FT 71aa; similar to others located within antibiotic synthesis FT clusters egs. TR:O52824 (EMBL:AJ223999) hypothetical FT protein located within the vancomycin biosynthesis cluster FT in Amycolatopsis orientalis (56 aa) fasta scores; opt: 281, FT z-score: 402.6, E(): 4e-15, (67.3% identity in 52 aa FT overlap) and SW:YBDZ_ECOLI hypothetical protein located FT within the enterobactin region of Escherichia coli (72 aa) FT fasta scores; opt: 186, z-score: 272.4, E(): 7.3e-08, FT (32.8% identity in 64 aa overlap)." FT /db_xref="InterPro:IPR005153" FT /db_xref="UniProtKB/TrEMBL:Q9Z388" FT /protein_id="CAB38589.1" FT /translation="MTNPFEDADGRYLVLVNDEGQHSLWPSFVDVPAGWTVALGESDRE FT ACLEYVEKNWTDMRPRSLVEAMSTGN" FT CDS complement(183388..184563) FT /transl_table=11 FT /gene="SCO3219" FT /gene_synonym="SCE8.12c" FT /product="putative lipase (putative secreted protein)" FT /note="SCE8.12c, possible lipase (putative secreted FT protein), len: 391 aa; weak similarity to many eukaryotic FT lipases e.g. SW:PAFA_CAVPO platelet-activating FT factor-acetylhydrolase from guinea pig (Cavia porcellus) FT (436 aa) fasta scores; opt: 153, z-score: 161.7, E(): 0.11, FT (22.9% identity in 319 aa overlap). Contains PS00120 FT Lipases, serine active site. Contains possible N-terminal FT region signal peptide sequence" FT /db_xref="GOA:Q9Z360" FT /db_xref="InterPro:IPR005065" FT /db_xref="UniProtKB/TrEMBL:Q9Z360" FT /protein_id="CAB38590.1" FT /translation="MPNVREAGRPARRCATLVAALLLALVPFGAGAPGTAAARAAPAAD FT AAWTASAVPAPTGALPVGVRTAHLRDTSRRDPWNPDRYRELALSLWYPALPSRAPRASY FT VTARESALILRFHRVEGVPADLLARFRVHARTAPPPLPAPARGLPLVLLSPGFALPRSS FT LTGLAEELASRGYAVAAVDHAYEAPAISHPDGRVTGCLACRRHPEGARVAATRAADLRF FT VRERLLRSPGAVGLPRLDPSRVAVVGHSMGGAAAFEALRTDAGFAAAANLDGTVHTGGR FT SPVDRPFLLLGAGEHGRPGADPTWQRAWRDLSGPRRWLSVRGAGHLSFTDYARLLERTG FT TAGEEVTLGAADAGRVTRELVVAFLDERLRRYGPRLDTAARQDPEVVTHGR" FT misc_feature complement(183805..183834) FT /note="PS00120 Lipases, serine active site." FT CDS complement(184771..185199) FT /transl_table=11 FT /gene="SCO3220" FT /gene_synonym="SCE8.13c" FT /product="putative secreted protein" FT /note="SCE8.13c, putative secreted protein, len: 142 aa; FT contains alanine-rich N-terminal region and possible FT N-terminal region signal peptide sequence" FT /db_xref="UniProtKB/TrEMBL:Q9Z4W4" FT /protein_id="CAB38591.1" FT /translation="MRGILRATALTAAIGAVALLPTTAASAAPAGPAASGCVTDSETED FT FGRGEITVCVEDGEVRVTGHVEDLKPGGPFNGGDSGCVGWWIDWETASGPDSSTSTLAC FT PHFTDKPYVEFDYDPTESEYGPKDVTGVADTHLTMVFM" FT CDS complement(185292..186146) FT /transl_table=11 FT /gene="SCO3221" FT /gene_synonym="SCE8.14c" FT /product="putative oxidoreductase" FT /note="SCE8.14c, probable oxidoreductase, len: 284 aa; FT similar to many e.g. TR:O52817 (EMBL:AJ223999) protein FT similar to prephenate dehydrogenase from the vancomycin FT biosynthesis of Amycolatopsis orientalis (367 aa) fasta FT scores; opt: 757, z-score: 865.8, E(): 0, (49.8% identity FT in 283 aa overlap) and SW:TYRA_BACSU prephenate FT dehydrogenase from Bacillus subtilis (372 aa) fasta scores; FT opt: 251, z-score: 291.1, E(): 6.6e-09, (28.3% identity in FT 251 aa overlap)." FT /db_xref="GOA:Q9Z4W3" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9Z4W3" FT /protein_id="CAB38592.1" FT /translation="MRSVVIVGAGVIGRSVGLALRRHGVTTYLTDADPEAALAGERCGA FT GFAAPPPRQADIAVLAVPPDQVAPVLAEHQKLGTARCYTDVSGVKVRLHREVRAHGCDL FT TSLVSGAPVVGGSGPVQARADLFDGRPWALTPTEATGNLALNCALELVALCGAVSVLLD FT PETHDRAVALVSHAPHLVASLVAARLLGGDESAVRLAGQDLRDVTRTADANPERWARIL FT TANAGPVADQLDDWAAEAQAMARELRDAARSGDTDGPVRLRETLRFGVAGRARIREPHT FT PSS" FT CDS complement(186244..186699) FT /transl_table=11 FT /gene="SCO3222" FT /gene_synonym="SCE8.15c" FT /product="putative secreted protein" FT /note="SCE8.15c, possible small secreted protein, len: 169 FT aa; similar to TR:Q9K3L2 (EMBL:AL360055) Streptomyces FT coelicolor putative secreted protein SCG20A.28c, 150 aa; FT fasta scores: opt: 727 Z-score: 859.9 E(): 2.9e-40; 72.109% FT identity in 147 aa overlap. Contains possible N-terminal FT signal sequence" FT /db_xref="InterPro:IPR016090" FT /db_xref="PDB:1FAZ" FT /db_xref="UniProtKB/TrEMBL:Q9Z4W2" FT /protein_id="CAB38593.1" FT /translation="MRTTTRTRTTLAAVGAALALGVAAAPAQAAPADKPQVLASFTQTS FT ASSQNAWLAANRNQSAWAAYEFDWSTDLCTQAPDNPFGFPFNTACARHDFGYRNYKAAG FT SFDANKSRIDSAFYEDMKRVCTGYTGEKNTACNSTAWTYYQAVKIFG" FT CDS complement(186854..187648) FT /transl_table=11 FT /gene="SCO3223" FT /gene_synonym="SCE8.16c" FT /product="putative ABC transporter integral membrane FT protein" FT /note="SCE8.16c, probable ABC transporter integral membrane FT protein, len: 266aa; located directly downstream of a FT probable ABC transporter ATP-binding protein (6bp gap). FT Similar to many particularly TR:O86630 (EMBL:AL031155) an FT integral membrane protein located directly downstream of a FT probable ABC transporter ATP-binding protein (2bp gap) from FT Streptomyces coelicolor (279 aa) fasta scores; opt: 460, FT z-score: 539.7, E(): 9.4e-23, (37.0% identity in 273 aa FT overlap). Contains several probable membrane spanning FT hydrophobic regions." FT /db_xref="UniProtKB/TrEMBL:Q9Z4W1" FT /protein_id="CAB38594.1" FT /translation="MTTTTVPKLVGPVKGGGFKGAVAFEWTKFWSVRATWWNLAVGLLL FT TVAFAAMVGASADASAKKGVDVTMPAPHHASQAFLISQLTIVVLATLALTSEYSSGSIR FT TTLQSVPARGRMLRSKTLVVAAVVVASGFVFSLLGTLVAAPLMGDYGDYSSGQLFGTAL FT GAGVYLALLAVMAIGLGTVLRSAAGTITTLIMVLLALPQLMGVVGAKWLETASDYMPSV FT AGTVLLTQDSDPYGAGTALLVLLLWALAAYAAGTAVLRRRDA" FT CDS complement(187655..188608) FT /transl_table=11 FT /gene="SCO3224" FT /gene_synonym="SCE8.17c" FT /product="putative ABC transporter ATP-binding protein" FT /note="SCE8.17c, probable ABC transporter ATP-binding FT protein, len: 317aa; similar to many egs. TR:O86629 FT (EMBL:AL031155) ABC transporter ATP-binding protein from FT Streptomyces coelicolor (312 aa) fasta scores; opt: 1080, FT z-score: 1174.5, E(): 0, (57.4% identity in 303 aa overlap) FT and SW:BCRA_BACLI bacitracin-resistance ABC transporter FT from Bacillus licheniformis (306 aa) fasta scores; opt: FT 567, z-score: 621.0, E(): 2.8e-27, (42.4% identity in 217 FT aa overlap). N-terminal region previously sequenced FT therefore identical to TR:P72389 (EMBL:U51332) partial, FT designated D7 (103 aa) fasta scores; opt: 666, z-score: FT 734.8, E(): 0, (99.0% identity in 103 aa overlap). Contains FT Pfam match to entry PF00005 ABC_tran, ABC transporter, FT score 151.20, E-value 1.9e-41 and PS00017 ATP/GTP-binding FT site motif A (P-loop)." FT /db_xref="GOA:Q9S6T6" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9S6T6" FT /protein_id="CAB38595.1" FT /translation="MITLDRLTKRYGDKTAVSDLSFEINPGKVTGFLGPNGAGKSTTMR FT MIVGLDAPTSGRALVGGKRYEELRHPLREVGALLDARAGHPGRSARHHLLGLARSNGIP FT ASRVGEVLQTVGLSEVANKRIGSFSLGMGQRLGIAAALLGDPKVLLFDEPVNGLDPDGV FT RWVRELMRSLAAEGRTIFVSSHLMSEMQETADHLLVIGRGKIIADAPIEEVIAGSSLTA FT VRVRTPQPDVLRRELLEFGLRVEPNADSAPDELLVVGGTLEEIGDLAFHHRVPIHELSM FT RKASLEQAYMELTAASVEYGSPALSQVTEVPDHQKA" FT misc_feature complement(188000..188530) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 151.20, E-value 1.9e-41." FT misc_feature complement(188486..188509) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 188745..190460 FT /transl_table=11 FT /gene="SCO3225" FT /gene_synonym="SCE8.18" FT /gene_synonym="absA1" FT /product="two component sensor kinase" FT /note="SCE8.18, absA1, two component sensor kinase, len: FT 571aa; sequenced previously therefore identical to FT TR:Q53893 (EMBL:U51332) AbsA1, predicted sensor histidine FT kinase which acts as part of a two component signal FT transduction system in the global regulation of antibiotic FT synthesis in Streptomyces coelicolor (571 aa) fasta scores; FT opt: 3782, z-score: 3585.7, E(): 0, (100.0% identity in 571 FT aa overlap)." FT /db_xref="GOA:Q53893" FT /db_xref="InterPro:IPR011712" FT /db_xref="UniProtKB/TrEMBL:Q53893" FT /protein_id="CAB38596.1" FT /translation="MHRWQAVRRRIESLVRVLGSERPFTRRADLVLLLVLLVPSAFATG FT TLETAPVAWLTACLLIAAAVVVQRTAPLLSLLLAALLTLFYPWFGANLWPSMATVVLSC FT LAGRRLTRLWPAHLVFLCVAAAGLLLVATVGQGKDWLSLLMTEFVACVLPWWAGNWWSQ FT RTALTHAGWEHAEQLEWRQRYIADQARMKERARIAQDIHDSLGHELSVMALLAGGLELA FT PGLSDPHRESVGQLRERCTMATERLHEVIGLLREDPNPSLTPADESVAQLVRRFQRSGT FT PVRFQEDGARDRPGTPLLSDLAAYRVVQEALTNAAKHAPGAPIDVRVTHTADETVVSVV FT NERPERGGSVPAAGSGSGLIGLDERVRLAGGTLRTGPRAGGFEVYARLPRGASSPSRST FT EPPGPADGDGTAGGSGDGTAPGAATAGNEGRAAAAAADLPAPSGPWRSASRAALLRTRA FT RIRRDARRAALIPAVLGAAIVAFLGGLYVFTSATTSLAPEDYARIRVGETRADLAPALP FT ERRIKKPPPVTSEPSVPAGTTCEYYRASSGLLDFGGAMYRLCFKDDVLMAKDTL" FT CDS 190479..191147 FT /transl_table=11 FT /gene="SCO3226" FT /gene_synonym="SCE8.19" FT /gene_synonym="absA2" FT /product="two component system response regulator" FT /note="SCE8.19, absA2, two component system response FT regulator, len: 222aa; sequenced previously therefore FT identical to TR:Q53894 (EMBL:U51332) AbsA2, predicted FT response regulator which acts as part of a two component FT signal transduction system in the global regulation of FT antibiotic synthesis in Streptomyces coelicolor (222 aa) FT fasta scores; opt: 1376, z-score: 1584.1, E(): 0, (100.0% FT identity in 222 aa overlap). Contains Pfam matches to FT entries PF00072 response_reg, Response regulator receiver FT domain, score 138.20, E-value 1.5e-37 and PF00196 GerE, FT Bacterial regulatory proteins, luxR family, score 70.90, FT E-value 2.7e-17. Contains a probable helix-turn-helix motif FT at 171-192aa (Score 1177 (+3.20 SD))." FT /db_xref="GOA:Q53894" FT /db_xref="HSSP:1A04" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q53894" FT /protein_id="CAB38597.1" FT /translation="MIRVLLADDETIIRAGVRSILTTEPGIEVVAEASDGREAVELARK FT HRPDVALLDIRMPEMDGLTAAGEMRTTNPDTAVVVLTTFGEDRYIERALDQGVAGFLLK FT ASDPRDLISGVRAVASGGSCLSPLVARRLMTELRRAPSPRSEVSGERTTLLTKREQEVL FT GMLGAGLSNAEIAQRLHLVEGTIKTYVSAIFTQLEVRNRVQAAIIAYEAGLVKDADLNR FT " FT misc_feature 190482..190823 FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 138.20, E-value 1.5e-37." FT misc_feature 190932..191129 FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 70.90, E-value FT 2.7e-17." FT CDS complement(191137..192471) FT /transl_table=11 FT /gene="SCO3227" FT /gene_synonym="SCE8.20c" FT /gene_synonym="SCE63.06" FT /product="putative aminotransferase" FT /note="SCE8.20c, partial CDS, possible aminotransferase, FT len: 431 aa; similar to many of undefined function e.g. FT TR:O52815 (EMBL:AJ223998) a protein similar to FT aminotransferase, from a cluster of genes involved in the FT biosynthesis of a vancomycin group antibiotic in FT Amycolatopsis orientalis (Actinomycete) (438 aa) fasta FT scores; opt: 953, z-score: 1093.1, E(): 0, (48.4% identity FT in 426 aa overlap). Also similar to TR:Q64602 (EMBL:Z50144) FT kynurenine/alpha-aminoadipate aminotransferase from rat FT (Rattus norvegicus) kidney (425 aa) fasta scores; opt: 293, FT z-score: 338.4, E(): 1.5e-11, (25.8% identity in 419 aa FT overlap)." FT /note="SCE63.06, partial CDS, possible aminotransferase, FT len: >45 aa; similar to the N-terminal region of TR:O52815 FT (EMBL:AJ223998) a protein similar to aminotransferase from FT a cluster of genes nvolved in the biosynthesis of a FT vancomycin group antibiotic in Amycolatopsis orientalis FT (Actinomycete) (438 aa) fasta scores; opt: 87, z-score: FT 147.0, E(): 0.69, (45.2% identity in 31 aa overlap). The FT remainder of this CDS lies on the neighbouring Streptomyces FT coelicolor cosmid E8." FT /db_xref="GOA:Q8CJX3" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:Q8CJX3" FT /protein_id="CAD55497.1" FT /translation="MTTTTPARTDRDGVLARTALHPSLSAPLLDTMNFLNEVTLRYPQA FT ISFAPGRPYEGDFDVARVPGYIETYLDHLRGRGHSEERVRTALYQYGETAGQIRDIVAR FT MLEVDEDLTVDPASVVVTVGCQEAVLLTLRALFTGPEDVLLVDSPAYVGITGAAGLLDI FT PVVPVPGTPDGPSPEGLERTVREIEASGRRARCLYVVPDCSNPTGVSLRREARTALLDA FT AARLDLLLLEDNPYGVFSRVRRPTLKSLDTERRVVYLGSFAKTAFPGARVGFVVADQLV FT AGADGRPPGLLAHELAKVKSMVTVNTPTLSQAAVAGLLLQNGGGLRAANEASARHYQST FT MRCLRDTLAAELPPGAPESGGVRWNDPDGGFFLTLDVPFEADEAALDVSAEKYGVIWTP FT MRHFHLDDAGDRQIRLSCSYLTTDRAAEGATRLARFVKDRAASNG" FT CDS complement(192468..193601) FT /transl_table=11 FT /gene="SCO3228" FT /gene_synonym="SCE63.05" FT /product="putative glycolate oxidase" FT /note="SCE63.05, probable glycolate oxidase, len: 377 aa; FT similar to many both prokaryotic and eukaryotic e.g. FT TR:O52792 (EMBL:AJ223998) similar to glycolate oxidase from FT a cluster of genes nvolved in the biosynthesis of a FT vancomycin group antibiotic in Amycolatopsis orientalis FT (Actinomycete) (357 aa) fasta scores; opt: 995, z-score: FT 998.4, E(): 0, (47.5% identity in 343 aa overlap) and FT SW:GOX_SPIOL glycolate oxidase from Spinacia oleracea FT (spinach) (369 aa) fasta scores; opt: 917, z-score: 920.7, FT E(): 0, (41.9% identity in 360 aa overlap). Contains Pfam FT match to entry PF01070 FMN_dh, FMN-dependent de FT hydrogenase, score 412.60, E-value 3.6e-120 and PS00557 FT FMN-dependent alpha-hydroxy acid dehydrogenases active FT site." FT /db_xref="GOA:Q9Z4X8" FT /db_xref="HSSP:1GOX" FT /db_xref="InterPro:IPR017934" FT /db_xref="UniProtKB/TrEMBL:Q9Z4X8" FT /protein_id="CAB38520.1" FT /translation="MREPLTLDDFARLARGQLPAATWDFIAGGAGRERTLAANEAVFGA FT VRLRPRALPGIEEPDTSVEVLGSRWPAPVGIAPVAYHGLAHPDGEPATAAAAGALGLPL FT VVSTFAGRSLEEVARAASAPLWLQLYCFRDHETTLGLARRARDSGYQALVLTVDTPFTG FT RRLRDLRNGFAVPAHITPANLTGTAAAGSATPGAHSRLAFDRRLDWSFVARLGAASGLP FT VLAKGVLTAPDAEAAVAAGVAGIVVSNHGGRQLDGAPATLEALPEVVSAVRGRCPVLLD FT GGVRTGADVLAALALGARAVLVGRPALYALAVGGASGVRRMLTLLTEDFADTMVLTGHA FT ATGTIGPDTLAPPHHAPPHHGPPTAPRPAPHRDRSHG" FT misc_feature complement(192546..193562) FT /note="Pfam match to entry PF01070 FMN_dh, FMN-dependent de FT hydrogenase, score 412.60, E-value 3.6e-120" FT misc_feature complement(192840..192860) FT /note="PS00557 FMN-dependent alpha-hydroxy acid dehydrogena FT ses active site." FT CDS complement(193751..194866) FT /transl_table=11 FT /gene="SCO3229" FT /gene_synonym="SCE63.04" FT /product="putative 4-hydroxyphenylpyruvic acid dioxygenase" FT /note="SCE63.04, probable 4-hydroxyphenylpyruvic acid FT dioxygenase, len: 371 aa; similar to many both prokaryotic FT and eukaryotic e.g. TR:O52791 (EMBL:AJ223998) similar to FT hydroxyphenyl pyruvate dioxygenase from a cluster of genes FT involved in the biosynthesis of a vancomycin group FT antibiotic in Amycolatopsis orientalis (Actinomycete) (357 FT aa) fasta scores; opt: 989, z-score: 1130.3, E(): 0, (48.7% FT identity in 355 aa overlap) and SW:HPPD_MOUSE hpd, FT 4-hydroxyphenylpyruvic acid dioxygenase from Mus musculus FT (mouse) (392 aa) fasta scores; opt: 610, z-score: 698.5, FT E(): 1.3e-31, (31.6% identity in 361 aa overlap)." FT /db_xref="GOA:Q9Z4X7" FT /db_xref="InterPro:IPR005956" FT /db_xref="UniProtKB/TrEMBL:Q9Z4X7" FT /protein_id="CAB38519.1" FT /translation="MLPPFPFLHWRAAMPPSDIAYAELYVADDREASGFLVDSLGFVPL FT AVAGPATGTHDRRSTVLRSGEVTLVVTQALAPDTPVARYVERHGDSIADLAFGCDDVRS FT CFDRAVLAGAEALQAPTPSHRAGQDAWFATVSGFGDIRHTLVPAADGDGAGLLPPDRDW FT ALLPAATGRTGPRPLLDHVAVCLESGTLRSTAEFYEAAFDMPYYSSEYIEVGEQAMDSI FT VVRNAGGGITFTLIEPDDTRVPGQIDQFLSAHDGPGVQHLAFLVDDIVGSVRSLGDRGV FT AFLRTPGAYYDLLTERVGAMADAIEDLRETNVLADRDEWGYLLQIFTRSPYPRGTLFYE FT YIQRNGARGFGSSNIKALYEAVEREREVAGR" FT CDS 195135..217526 FT /transl_table=11 FT /gene="SCO3230" FT /gene_synonym="SCE63.03c" FT /gene_synonym="cdaPSI" FT /product="CDA peptide synthetase I" FT /note="SCE63.03c, cdaPSI, CDA peptide synthetase I, len: FT 7463 aa; part of the calcium-dependent antibiotic (CDA) FT biosynthetic cluster from Streptomyces coelicolor. CDA is a FT peptide antibiotic which is synthesised non-ribosomally by FT a putative multifunctional peptide synthetase enzyme. This FT CDS encodes a subunit of this enzyme and is suspected to be FT responsible for the incorperation of the first 6 amino FT acids into the antibiotic structure. This ORF overlaps the FT downstream (cdaPSII) ORF by one base indicating possible FT translational coupling. Contains eight separate Pfam FT matches to entry PF00668 DUF4, Domain of unknown function FT (U), six separate Pfam matches to entry PF00501 FT AMP-binding, AMP-binding enzyme (A) and six separate Pfam FT matches to entry PF00550 pp-binding, Phosphopantetheine FT attachment site (P). These Pfam matches cover the full FT length of the protein in the following order from N to FT C-terminal U-A-P-U-A-P-U-A-P-U-U-A-P-U-A-P-U-A-P-U." FT /db_xref="GOA:Q9Z4X6" FT /db_xref="HSSP:1AMU" FT /db_xref="InterPro:IPR010071" FT /db_xref="UniProtKB/TrEMBL:Q9Z4X6" FT /protein_id="CAB38518.1" FT /translation="MSENSSVRHGLTSAQHEVWLAQQLDPRGAHYRTGSCLEIDGPLDH FT AVLSRALRLTVAGTETLCSRFLTDEEGRPYRAYCPPAPEGSAAVEDPDGVPYTPVLLRH FT IDLSGHEDPEGEAQRWMDRDRATPLPLDRPGLSSHALFTLGGGRHLYYLGVHHIVIDGT FT SMALFYERLAEVYRALRDGRAVPAAAFGDTDRMVAGEEAYRASARYERDRAYWTGLFTD FT RPEPVSLTGRGGGRALAPTVRSLGLPPERTEVLGRAAEATGAHWARVVIAGVAAFLHRT FT TGARDVVVSVPVTGRYGANARITPGMVSNRLPLRLAVRPGESFARVVETVSEAMSGLLA FT HSRFRGEDLDRELGGAGVSGPTVNVMPYIRPVDFGGPVGLMRSISSGPTTDLNIVLTGT FT PESGLRVDFEGNPQVYGGQDLTVLQERFVRFLAELAADPAATVDEVALLTPDERERVLD FT GWNDTAHEVPETTLPELFAARAARTPGHEALVYEGTSLTYAELDARAERLAGALTARGA FT GPERFVAVAVERSAELVVALLAVLKSGAAYVPVDPGYPADRIAHILRDAGAMLVLTTRD FT TAERLPGDGTPRLLLDEPAAAGTTAAGAPAPPGTLPRALPAPGHPAYVIYTSGSTGRPK FT GVVISHRAIVNRLAWMQDTYGLEPSDRVLQKTPSGFDVSVWEFFWPLVQGATLVVARPG FT GHTDPAYLAGTVRREGVTTLHFVPSMLDVFLREPAAAALGGATPVRRVFCSGEALPAEL FT RARFRAVSDVPLHNLYGPTEAAVDVTYWPCAEDTGDGPVPIGRPVWNTRMYVLDAALRP FT VPAGVPGELYIAGVQLARGYLGRPALSAERFTADPHGAPGSRMYRTGDLARWNHDGSLD FT YLGRADHQVKLRGFRIELGEIEAALVRQPEIAQAAVVLREDRPGDQRLVAYTVPARDAD FT TLTGPPAEAGTHPGPGAAPDTDPATGPAAGTDSGPGSGTGSGTGSGTGSGARPGPDGTA FT THTVAGAGPAAAGETAAGADAGTGTGETGAGADAGTGTGAHAGPDGAVLAARLRELLPG FT YMVPSAFVALPRLPVTPNGKLDRRALPAPAESGRAAGRAPRTPGEELLCALFAEVLGVA FT EVRVDDGFFDLGGHSLLATRLISRIRATAGAEVPIRRVFEAPTVAELAPALTDGGRARA FT AVTARPRPDRLPLSFAQRRLWFIHQYEGPSPLYNIPAALRLTGPVDGAALSAALGDVVA FT RHESLRTVFAEDAHGPHQVILSAERAAPRLKTLDSDPERLAADLARTARHTFDLTRDVP FT LRATLLRVAPEEHVLLLVLHHIAGDGWSLAPLARDLGTAYAARTAGTAPDWAPLPVQYA FT DYTLWQRELLGADGNGAGTGDGGEGARQLAHWREALAGLPERLELPSDRPRPARRDNSG FT ARLDVSVPAGLHRSLAALAAETRTSVFMVLQAALAGLLTRLGAGEDVPIGSTIAGRTDA FT AVENLVGFFVNTLVLRTDTGGDPAFRELLSRVRERDLAAYAHQDVPFERLVEAVNPDRA FT TSHHPLFQVMLTFDTTQQDALGELGRLPGITTSLLPVHTGLSRFDLVFAFDERRDAAGG FT QAGLDLAVEFSTELFDAGTVRALTERLLLLLTQVAADPGVRLGDLDVLLPGEHHDLLVA FT ANRPGTAPASPAPASPEPASPEPASPAPGTATLPELFERQAARHPDRTALTFEGTSLSY FT AELNARANRLARLLTARGIGPDALVALALPRSAELVVALLAVVKSGAAYVPLDPGYPAD FT RLAHALSDSAPAALLTDRATAGRLPAHEVPRIVLDAPAPADGGTTGGDPADAHPATDLA FT QGERVRPLDPRDTAYVIYTSGSTGRPKGVAVPHGNVVRLFSATAPWFGFDEHDVWTLFH FT SYAFDFSVWELWGPLLHGGRLVVVPHDVTRDPAAFLALLARERVTVLNQTPSAFHQLAA FT ADRENPTELALRTVVFGGEALDLSRLADWYERHAEDAPALVNMYGITETTVHVSHFALD FT RATAAASSASTIGVNIPDLRVYVLDDRLRPTAPGVTGEMYVAGAGLARGYLGRPALTAD FT RFPADPYAALFGERGTRMYRTGDLARRRTDGGLDYLGRADQQVKIRGFRIEPGEIEAVL FT AAHPAVDDVAVVAREDVQGDPRLVAYVVTGSGATARALHDHAAGHLPDHMLPSAFVTLD FT VLPLTPNGKLDTKALPAPAHAGQVTGRAPRGPREEILCALFAEVLGVPRLTVDDSFFDL FT GGHSLLATRLAGRIRGTLGVELSVRRLFETPTVAGLSAALDGAERSGTGPTAGERPERL FT PLSYAQQRLWFLHQLEGPSPTYNITGALRLTGDLDPGALRAAFQDVVTRHESLRTVFSE FT DGHGARQTVLDAAGVRFELPVADVSEDRLDARLEEAARHCFDLTTDIPVRAELFRLGAR FT EHVLLLMVHHIAGDGWSLGPLIRDLAAAYTARAARRAPDWAPLPVQYADFALWQRAALG FT DAADATSPAGRQLAHWKEALAGLPDRLELPADRPLPAVASHRGGRVPLTVPAPLHSGVA FT ELARESRTSVFMVLQAALAALLTRMGAGEDVPLGTPVAGRGDDAVDQVVGFFVNTLVLR FT TDTGGNPTFRALLDRVRDTDLTAYDHQDLPFEHLVDVLSPTRSLSHNPLFQVLLSLDTT FT QQDALAALSATGLGVRLLNVTTGVAKLDLALEIAEHRDADGAPAGLVGAAEYSADLFDE FT GTVTLLVERFLRLLDALVADPSRRIGDVDVLGPRERERVLTEWNDTPRRPVQGTFADHV FT ARHAAERPGHLAVETAGAAAPGGALTYGELNERANRLARALLARGAGPERFVAVALPRS FT ADLVLSALAAFKAGAAYLPVDPAHPAERITHLVSDAAPTLIVTTSALAASLPDTGTPVL FT LLDTPETAATLAALPGHDVTDADRPVPLRPEHPAYMIYTSGTTGRPKGVVVTHTGLPGL FT LDIFTRDCAAGPGSRILQHLSPSFDASFWELAMGLLTGATLVVAPPETTPGPELAELAT FT RHAATHLSLTTSVLGLLPPDSLPDGLTLVVGAEAIPPELVERWSPGRTMLNSYGPTETT FT VCSTMSGPLSGPAVPPIGSPVANSAVYVLDAALRPVPPGVPGELYAAGAHLARGYHDRR FT ALTAERFVANPFGEPGSRLYRTGDLVRWRPDGQLEYLGRADTQVKIRGLRIEPTEIEAV FT ITERPHLARAAVIVREDRPGDRRLVAYVVPEPGATVDTAELRAALRETLPDHMIPTAFV FT VLDALPLTLNGKLDRKALPAPDYSARTSGRAARDPRERLLTALFGEILGVEPAGVDDGF FT FDLGGDSILSIQLVARARAAGLVLSVRDVFEHQTPALLARSAAAAPAGDRTARDSDVPA FT DGPAPRTPMMGWFAALGSDLAAFNQSLVLRVPAALDPDTLDTALRAVLDRHDALRMRVA FT DDWTIEIPPPGSVTPADCLVRFDAVGLDEAAVRSAVTEQARTARDRLAPADGRMLQAVW FT LDRGADRDGLLLLVANHLVVDGVTWRILVPDLAAAYAGETLAPVGTPWRHWALSLSDLA FT GQPRTEEELDHWHSVLGDTPHTLRLDPARDTHATAGEITAELDADTTEALLTWVPGVCH FT ATVNDVFLSTFALAVAGWRRGRGEDADAPVVLDLESHGRHEEAVPGVELSRTAGWFTSM FT YPVRLAPPAGASGDGSALRALKAVKEQLRTVPGDGLGYGLLRHLNPRTRAALAALPLPE FT FGFNYLGRIGQEGTDEAPWTIEGGDVAGIDGAMPLAHPVDVNAVARETADGTRLRARWT FT YSRTALEPEDTQRLADTWFRLLRRLVEEARQPGAGGLTPSDIAHPALAQDEIEDLEHTV FT PGLQDILPLAPLQEGFLFLNLYDENARDVYVGQLAFDLEGSFDGTRMRAAAGALLRRHA FT NLRAGFRQTATGTWVQVVPAELEPDWRECDLTDRADEAERDAEAGRLAAGDRERRFDLT FT SPPLMRFTAIRLSADRVRLVMTNHHILLDGWSMPLLWQELTELYVSGGDPVSLPPVRPY FT RDHLAWLGARDRDAARDAWRRSLSGLDEATLLAPDAGPAEAAPLGIPFGLDRDATAALS FT AWARGRGVTMNTVVQGAWALALAQATGRDDVVFGATVSGRPPELPGVESMIGLFINTLP FT VRARLDQAEPLGDLFRRLQNEQARLLDHQWPGLADIQHWAGHGELFDTAMVFQNYPVSA FT DTTSRQLDGLRVAGYDAVESTDFAVNLVAHTRDDALRLRLDYRADACAGDLVRSLADRM FT LRVLEALVTDSDRPVAHLDTLDPAVRERVLVEWNGAPTQLPGTPLHELISEQARLTPDA FT VAVVCDGTSLTYAELDGGANQLARHLLGEGLGAEDFVAIALAKSLDAVISMLAVLKTGA FT AYLPIDPDYPAERITYMLDDARPALTLTEPVPVERYTGHSVTAVTDEERRSPWSARHAA FT YMIYTSGSTGRPKGVVIEHHALATYLHRARNTYTAMTGVTVLHSPLAFDLTITALWTPL FT TSGGTVHLTSLEESDTQPSLIKATPSHLPLLTTLPETASPSHTLILGGEALHTDHLVTW FT RTQHPGVQIINAYGPTESTVNITDHHVGEDTPDGPVPIGRPFANTQVYVLDSALRPVAP FT GVTGELYLAGEQLARGYLGRPALTAERFTANPHSSTPGARMYRTGDLAHWNHHGHLTYD FT GRADHQIKLRGHRIEPGEIEATLTAQTGITQATVQLREDQPGDQRLVAYLVVNDSTEYD FT EKTVRDALTSALPDYMVPSALVTLDALPLTPNGKLDRTALPAPAYSASTAGRAPRTPRE FT EVLCTLFAEVLGVDLVTIDDNFFDLGGHSLLATRLVSRTRTALGVELSIRQLFETPTVA FT GLAEALDASGTVRTALTARPRPERIPLSYAQQRLWFLHQLEGPSATYNTVLTLRLGGAL FT DVDALRAAISDVVARHESLRTVFTEDERGAYQIVLPVEAASTPFTVVDVAEEEIGDRLD FT EAVGHCFDLAQELPARTSLFRVSEREHVLLLLIHHIASDAWSRAPLAQDLTAAYAARVR FT SEAPMWAPLTVQYADYALWQQEILGDDTDADSLAGRQLAYWKQQLAGLPEQLDLPTDRP FT RPAVAGYSGDRVPFTVPTELHTRLTELARATNTSAFMVIQAAVAVLLTRLGAGEDIPIG FT TPVAGRTDDAADDLIGLFINTLVLRTDTSGDPTFRRLLDRVRDTDLAAYAHQDLPFERL FT VEALNPARTLSHHPLFQVLLTFNNTDHEGALKDISELPGLTVALREVQRTSSKFDLSFG FT FAESFDTSRRPQGIEAALDFSTELLDRRSAQAIADRFLRVLEAVTTAPDRPIGAVELMD FT PAERERVLVEWNGAPTQLPGTPLHELISEQARLTPDAVAVVCDGTTLTYAELDRRANQL FT ARHLLGEGLGAEDFVAIALAKSLDAVISMLAVLKTGAAYLPIDPDYPAERITYMLDDAQ FT PALTLTAPIPPASYDSRPTSEITDVERRSPWSARHAAYMIYTSGSTGRPKGVVIEHHAL FT ATYLHRARNTYTAMTGVTVLHSPLAFDLTITALWTPLTAGGTVHLTSLEEAEVQPSLIK FT ATPSHLPLLTTLPETASPSHTLILGGEALHTDHLATWRTQHPGAQIINAYGPTESTVNI FT TDHHVSEDTPDGPVPIGRPFANTQVYVLDSALRPVAPGVTGELYLAGEQLARGYLGRPA FT LTAERFTANPHSSTPGARMYRTGDLAHWNHDGHLTYDGRADHQIKLRGHRIEPGEIETT FT LTAQTGITQTTVQLREDTPGDQRLVAYLVVNDSTEYDEPTLRDALASALPDYMRPSAYV FT TLDALPLTPNGKLDRTALPAPAYSASTTGRTPRTPREEILCTLFAEVLGVDLVTIDDNF FT FDLGGHSLLATRLVSRARTALGVELSVRQFFETPTIAGLSGAFDRAGRARAALTARPRP FT ERIPLSYAQQRLWFLHQLEGPSATYNIPTTLRLTGTLDTDALQSALNDLLARHESLRTT FT YTEDGEGPRQVIHAWEPGMLPLGVVDTGEGELDAMLSAGVHHAFDLTAGIPVRATLFRI FT SEQEHVLLLLIHHIATDAWSRTPLGHDLAAAYSARCAGDVPAWEPLPVQYADYALWQRE FT VLGDEGDADAPAGRQLAYWTRQLADLPEQLDLPTDRPRPAVASQDGDRVAFSLDADLYV FT RLTELARATHSSTFMVVQAALAVLLTRLGAGEDIPIGTPVAGRTDDATENLVGFFVNTL FT VLRNDTSGNPTFRELLEETRRTDLAAYAHQDLPFERLVEALNPARTLAHHPLFQVMLIL FT STAETDPDASLALPGLRVGAERSRLGAAKVDLAFALAEVRDGEGRSTGLTGALDFRTDL FT FDRSTARSLVERFVRTLEAVVADPGVRLSRVPVLTGSERRSLLDRGTGPLLEGLDATLP FT ELFAEQALRTPGAPALVRGGTTVSYAELDLRTNRLARLLRQQGVRPGTPVVMLMERSPA FT HVVATLAIAKAGGAYVPLHDTYPLDRMRHVVADTAATLILTDRAEAARAGQLGARVMVV FT DEFGAAPSGSEADAAPGTGTGTGTGSRSGYVDDAPEVGLRPQDLAYVMYTSGSTGVPKG FT VAVTHRGVVDLVRDHCWRPGVHERVLLHAPHAFDVSCYEMWVPLVSGGTVVVAPPGHLD FT PAAITDLITAHDITAIHLTAGFFRVVAEEAPECFAGVREVLTGGDVVSPAAVARVLAHH FT PRIVLRHLYGPTETTLCVTQHEVTAPYEARGSLPVGRATGNTRAYVLDRYLQPVPAGVP FT GELFISGSGLARGYLDRPDLTCERFVADPYGGSGERMYRTGDLVRYNAAGELEYLARAD FT DQVKIRGFRVELGEIEAVLATRPELAQAAVVVREDRPGDRRLVGYVVAAAGRDGEVDPD FT ALRAFSRQALPDYMVPSAFVVLGTLPLTANGKLDRKALPAPDYGAASTGRAARTPAEEL FT LCTLFAQVLGLSAVGVDDGFFDLGGDSILSIQLVSRARAAGLALAVRDVFEHQSTARLA FT AALTDRDDAASVPEAEAVPPYGPAPLTPVMARIAELGLGGDDFNQSVVVSLPPAVDRDR FT LVPALQRVLDHHDALRLRVLPDGSTEVRAPGSVPAADVLSVVTRAPGATGEARDALLVE FT AACAARDRLAPAEGRMLQAVLVDGTDDTDGTGGTSGADGVLILVAHHLVVDSVTWSIVV FT PDLAAAYRGEEPAPVGTSWRQWATSLARLATDPRVEAETAHWEHTLTGAGTLRLDRGRD FT LQGDAGRISLDLAPHTTEALLTRLPGGVNASVHDVLLTAFAFAVAGWRRGRGEDPDAPV FT VLDLESHGRHEEAVPGAELSRTAGWFTALHPVRLAPDVTDWARLHQDGDALRDGLKQVK FT EQLRSVPGDGLGHGLLRHLNPTAGPRLARLPEPDFGFNYLGRRVTPATGTPEPWTVTGG FT GLAASRPTAPMAHAVELSAVVHEGADGPRLRAEWTYARRLVPDHDARRLAEQWFRALEA FT LVEQADRAGTGGLTPSDVTLGSLSQSEIEEFESDLESEWEIEQ" FT misc_feature 195147..196337 FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 80.00, E-value 5e-20" FT misc_feature 195543..195575 FT /note="PS00639 Eukaryotic thiol (cysteine) proteases FT histidine active site." FT misc_feature 196623..197855 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 601.30, E-value 5.6e-177" FT misc_feature 197004..197039 FT /note="PS00455 Putative AMP-binding domain signature." FT misc_feature 198414..198608 FT /note="Pfam match to entry PF00550 pp-binding, Phosphopante FT theine attachment site, score 74.30, E-value 6.3e-19" FT misc_feature 198483..198530 FT /note="PS00012 Phosphopantetheine attachment site." FT misc_feature 198651..199853 FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 318.40, E-value 8.5e-92" FT misc_feature 200220..201497 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 563.60, E-value 1.2e-165" FT misc_feature 200625..200660 FT /note="PS00455 Putative AMP-binding domain signature." FT misc_feature 201744..201938 FT /note="Pfam match to entry PF00550 pp-binding, Phosphopante FT theine attachment site, score 82.80, E-value 2.8e-21" FT misc_feature 201813..201860 FT /note="PS00012 Phosphopantetheine attachment site." FT misc_feature 201981..203165 FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 302.10, E-value 6.9e-87" FT misc_feature 203487..204686 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 484.60, E-value 8.1e-142" FT misc_feature 203739..203756 FT /note="PS00343 Gram-positive cocci surface proteins 'anchor FT ing' hexapeptide." FT misc_feature 203871..203906 FT /note="PS00455 Putative AMP-binding domain signature." FT misc_feature 204939..205121 FT /note="Pfam match to entry PF00550 pp-binding, Phosphopante FT theine attachment site, score 59.80, E-value 6.3e-15" FT misc_feature 205008..205055 FT /note="PS00012 Phosphopantetheine attachment site." FT misc_feature 205179..206387 FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 166.50, E-value 4.5e-46" FT misc_feature 206604..207755 FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 275.20, E-value 8.5e-79" FT misc_feature 208044..209177 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 435.90, E-value 3.5e-127" FT misc_feature 208371..208406 FT /note="PS00455 Putative AMP-binding domain signature." FT misc_feature 209430..209624 FT /note="Pfam match to entry PF00550 pp-binding, Phosphopante FT theine attachment site, score 87.10, E-value 1.8e-22" FT misc_feature 209667..210857 FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 322.70, E-value 4.3e-93" FT misc_feature 211164..212297 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 453.50, E-value 1.8e-132" FT misc_feature 211491..211526 FT /note="PS00455 Putative AMP-binding domain signature." FT misc_feature 212550..212744 FT /note="Pfam match to entry PF00550 pp-binding, Phosphopante FT theine attachment site, score 84.80, E-value 7.6e-22" FT misc_feature 212619..212666 FT /note="PS00012 Phosphopantetheine attachment site." FT misc_feature 212787..213971 FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 313.50, E-value 2.5e-90" FT misc_feature 213075..213107 FT /note="PS00626 Regulator of chromosome condensation (RCC1) FT signature 2." FT misc_feature 214278..215537 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 471.80, E-value 5.5e-138" FT misc_feature 214701..214736 FT /note="PS00455 Putative AMP-binding domain signature." FT misc_feature 215796..215987 FT /note="Pfam match to entry PF00550 pp-binding, Phosphopante FT theine attachment site, score 69.40, E-value 1.5e-17" FT misc_feature 215865..215912 FT /note="PS00012 Phosphopantetheine attachment site." FT misc_feature 216036..217289 FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 108.80, E-value 1.1e-28" FT CDS 217523..228535 FT /transl_table=11 FT /gene="SCO3231" FT /gene_synonym="SCE63.02c" FT /gene_synonym="cdaPS2" FT /product="CDA peptide synthetase II" FT /note="SCE63.02c, cdaPS2, CDA peptide synthetase II, len: FT 3670 aa; part of the calcium-dependent antibiotic (CDA) FT biosynthetic cluster from Streptomyces coelicolor. CDA is a FT peptide antibiotic which is synthesised non-ribosomally by FT a putative multifunctional peptide synthetase enzyme. This FT CDS encodes a subunit of this enzyme and is suspected to be FT responsible for the addition of 3 amino acids to the FT peptide antibiotic. This ORF overlaps the upstream (cdaPSI) FT and downstream (cdaPSIII) ORFs by one base indicating FT possible translational coupling of all three. Contains four FT separate Pfam matches to entry PF00668 DUF4, Domain of FT unknown function (U), three separate Pfam matches to entry FT PF00501 AMP-binding, AMP-binding enzyme (A) and three FT separate Pfam matches to entry PF00550 pp-binding, FT Phosphopantetheine attachment site (P). These Pfam matches FT cover the full length of the protein in the following order FT from N to C-terminal U-A-P-U-A-P-U-A-P-U. The first and FT third Pfam matches to entry PF00501 also contain Prosite FT matches to PS00455 Putative AMP-binding domain signature. FT All three Pfam matches to entry PF00550 also contain FT Prosite matches to PS00012 Phosphopantetheine attachment FT site." FT /db_xref="GOA:Q9Z4X5" FT /db_xref="HSSP:1AMU" FT /db_xref="InterPro:IPR010071" FT /db_xref="UniProtKB/TrEMBL:Q9Z4X5" FT /protein_id="CAB38517.1" FT /translation="MSQQPTRARGKIEDILPLSPLQEGFVFLGLLHTEGPDLYIGQVAF FT DLEGPFDGARMREAARALLRRHANLRAGFRQRKNGAWAQLVLRDVDLPWQDADLSTLSE FT EERRAEADRLAAADRARRFDLGRPPLLRFTAIRLSADRVRLVMTNHHIVLDGWSMPVLL FT RELMALYAAEGDPSALPRVRPYRDYLAWLDARDRDAARDAWRRSLSGLDEATLLAPDAG FT PASTAPSQVSFTVDSEVSGALSAWARGQGVTMNTVVQGAWALALAQATGRDDVVFGATV FT SGRPPELPGVESMIGLFINTLPVRARLDQAEPLGDLFRRLQNEQARLLDHQWPGLADIQ FT HWAGHGELFDTAMVFQNYPVEEGDLTAPADPDRLRVASADIKGGTHFAVNVVATMRGAE FT LSFRVDYRPDLYDEAYARDFGRRMLRVLETLISDPDRPVAHLDTLDPAVRERVLVEWNG FT APTQLPGTPLHELISEQARLTPDAVAVVCDGTSLTYAELDGRANQLARHLLERGLGAED FT FVAIALHKSLDAVTSMLAVLKTGAAYLPIDPDYPAERITYMLDDARPALTLREPVPAAA FT YGHRPTDDVTDAERRTPWSALHAAYMIYTSGSTGRPKGVVIEHHALATYLHRARNTYTA FT MTGVTVLHSPLAFDLTITALWTPLTAGGTVHLTSLEEAEVQPSLIKATPSHLPLLTNLA FT ATASPSHTLILGGEALHTDQLTDWRTQHPGAQIINAYGPTESTVNITDHRLDGTEEGPV FT PIGRPFANTQVYVLDSALRPVAPGTTGELYLAGEQLARGYLGRPALTAERFTANPHSSV FT PGARMYRTGDLAHWNHHGHLTYDGRADHQIKLRGHRIEPGEIETTLTAQTGITQATVQL FT REDQPGDQRLVAYLVTSTGYDENTVRDALVSALPDYMVPSALVTLDALPLTPNGKLDRT FT ALPAPAYSASTTGRTPRTPREEILCTLYSEILSVNTVGIDDSFFDLGGHSLLATRLVSR FT IRTTLGRELPIRQLFETPTVAGLSRALDTSGTLRTALTARPRPERIPLSYAQQRLWFLH FT QLEGPTATYNIPTTLRLTGTLDTDALQSAFNDLLARHESLRTTYTEDDQGAQQIVLPVE FT AVATPFAVVDVAAEDVAERVAEAAAHAFDLGAEIPVRARLFRVSEREHVLLLLVHHIAS FT DAWSRGPLAQDLTAAYTARCADDAPAWQPLPVQYADYALWQQEILGDDTDPDTLAGRQL FT AYWKQQLAGLPEQLDLPTDRPRPATADHTGDRVTFTVPADLHTRLTELARETNTTAFMV FT IQAALAALLTRHGAGEDIPIGTPVAGRTDDATDHLIGFFVNTLVLRTDTSGNPTFRDLL FT TRVRDTDLTAYTHQDLPFERLVEALNPTRSLTHHPLFQTMLTLHNTQGTKTDRFAGLAA FT EVVASESVSARFDLSFALAEHFGADHSCAGMSGGVTYSTALFDRATVRDLADRLVRLLA FT AAVAHPGRSVGQLEIMDAAERRLVLQEWNDTAAEPPAASVTGLFERQARRSPGATALEF FT GEVRLSYAELNARANRLARHLVARGAAPGRFVAVALPRSAELVVTLLAVLKSGAAYLPI FT DPHYPADRVEYMLADAGPALTVTEPVAEAGLSGYGDADLGADELRGPVHGAHPAYTIYT FT SGSTGRPKGVVVPRGALDNFLADMGRRFTPGSGDRLLAVTTVGFDIAGLEIFLPLLHGA FT VLVLADEETARDPHALLHRVSASGITMVQATPSLWQGVAAVAGDELAGVRVLVGGEALP FT SELARALTDRARSVTNLYGPTEATIWATAADVAESGPVIGRPLANTSAYVLDSALRPVP FT VGVPGELYLAGEQLAQGYHLRPALTSERFTADPYGPAGTRMYRTGDLVCRRRDGALRYL FT SRVDQQVKLRGFRIELGEIEAELSRHPAVAESAVTVREDRPGDRRLVGYVVPKGPEGPA FT GPTGPVPSARELRERLRGRLPEFMVPTAFVVLDALPLTPNRKLDRKALPAPEYDGEPVG FT RGPRDPREEILCALFAEVLGVARVGIDDGFFDLGGHSLLATRLVSRIRTALGVELSVRQ FT FFETPTIAGLSGALDRAAGARAPLAARPRPERVPLSPAQQRLWFLHQFEGPSATYNMPT FT ALRLSGPVDRAALERAIGDVLVRHESLRTVFAADDGGSWQVVLPADRAVGRLDVVDVTA FT GEVAERVGEAARHAFDLTADIPFLARLFRVSDTEHVLLLLIHHIAGDGWSMAPLARDLT FT AAYAARCAGAAPDWEPLPVQYADYALWQREVLGDESDPDSVAARQLAYWKDALAGLPEQ FT LELPTDRPRPATAGYTGDRIAFTVPTALHARLTELARSTHSSLFMVVQAAFATLLTRLG FT AGEDIPVGTAVAGRNDAATEDLVGFFVNTLVLRTDTGGNPTFRELLGRVRERDLAAYAH FT QDVPFERLVEALNPARSLAHHPLYQVMITFNNTAGAGDRTAPASPDTPDVSGQAGALLN FT ATRMTAGTGVAKFDLALTFGERHDPSGGPAGMRGSLEYRTELFDRETAESVISRLLGVL FT GSVTADPDRPIGGIGLLDPAERRQVLREWNDTARPQREGTLPRLFEEQVARTPRRPAFS FT AAGTTLTYAELNSRANRLAHLLAESGAGPEQVVAISLPPSVEMGVAVLAVLKTGAAYLP FT VDPGSPRERIATMAEDAAPVCALTTSAVPAGVFPAELPRLLLDDPDVTARLAAQPAHDL FT TDEDRTQPLSPWNAAYIIYTSGSTGRPKGVLVEHQPVLNYLAVSAELYPGVAGNALLHS FT PLSFDLTVTGLFAPLLNGGCVHLADLEELHARALDGEVPDLPQTTFLKATPSHLPLITG FT LPGVCVPDGELVLGGESLTGRAVRTLLAAHPGARVLNEYGPTETIVGCTTWRVEAPDDL FT ADGVLTIGRPFPNTRMLVLDPYLQPVPAGVPGELYVSGVQLARGYLNRPGQSASRFVAN FT PFEGPGERMYRTGDIVRWNRRGDLEFISRVDDQVKIRGFRVELGEVESALSRQPGVPEA FT VAVVREDRPGDRRLVAYLVTGAGPVPVPSDEELRERLRETLPDYMVPSAFVRLPELPLT FT GNGKLDRGRLPAPDYAAAGTGRAPVTAREELLCALFAEALGLESVGVDDGFFDLGGDSI FT LSIQLVSRARAKGLTLSVRDVFEHQSVARVAEALELAEAQAADGAAGASAGAVPGAAEE FT EAAASGPVPATPIMGWFAALGGPVAPFNQSVVVSVPADLDAERLVAALGALLDRHDSLR FT LRVAADWSMSVPEPEPGGTDAAGLLTRRAAGDVDDAGLHALLAEAGAAERDRLSPADGR FT MLRACHVDRGPDRPGLLVLVAHHLAVDAVSWRLLVPDLAAAYEGRPLSPAGTGWRRWAS FT ALRDLAGSPVTEAETDHWLDAARPAAEPADPVLDPARDTHARSGQVVLDLDPDTTDALL FT TWVPGVFRAEINDLLLTAFGLAVADWRRDRGARGTAPVTVDLESHGRHEHLVPGADLTR FT TTGWFTSMHPVPLHPEVDDPDWAEVWDGGAAAGRALKRVKEQLRAVPRDGVGHGLLRHL FT NPRTRDRFAALPTPAYGFNYLGRHTGGRGGGAPGGGAGPEPWSVLGRGVAGQHPDTPLA FT HPVELVAGAHDTDAGPTLHSVWTYADAVLSETEVRRLGEGWFRALKALVEHAGRPEASG FT LTPSDVSLTSLSEDDISRLESEWGSL" FT misc_feature 217556..218710 FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 290.10, E-value 2.7e-83" FT misc_feature 218999..220129 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 446.50, E-value 2.3e-130" FT misc_feature 219326..219361 FT /note="PS00455 Putative AMP-binding domain signature." FT misc_feature 220376..220570 FT /note="Pfam match to entry PF00550 pp-binding, Phosphopante FT theine attachment site, score 78.00, E-value 5.9e-20" FT misc_feature 220445..220492 FT /note="PS00012 Phosphopantetheine attachment site." FT misc_feature 220613..221791 FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 332.60, E-value 4.3e-96" FT misc_feature 222098..223246 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 472.70, E-value 3e-138" FT misc_feature 223523..223717 FT /note="Pfam match to entry PF00550 pp-binding, Phosphopante FT theine attachment site, score 88.00, E-value 1e-22" FT misc_feature 223592..223639 FT /note="PS00012 Phosphopantetheine attachment site." FT misc_feature 223760..224980 FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 326.10, E-value 3.9e-94" FT misc_feature 225287..226513 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 428.90, E-value 4.6e-125" FT misc_feature 225671..225706 FT /note="PS00455 Putative AMP-binding domain signature." FT misc_feature 226772..226963 FT /note="Pfam match to entry PF00550 pp-binding, Phosphopante FT theine attachment site, score 71.90, E-value 2.9e-18" FT misc_feature 226841..226888 FT /note="PS00012 Phosphopantetheine attachment site" FT misc_feature 227048..228295 FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 87.50, E-value 2.7e-22" FT misc_feature 228535..229515 FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 187.70, E-value 1.9e-52." FT CDS 228535..235788 FT /transl_table=11 FT /gene="SCO3232" FT /gene_synonym="SCE63.01" FT /gene_synonym="cdaPS3" FT /gene_synonym="SCE29.01" FT /product="CDA peptide synthetase III" FT /note="SCE63.01, partial CDS, cdaPS3, CDA peptide FT synthetase III, len: >332 aa; Constitutes the N-terminus of FT cdaPS3, CDA peptide synthetase III, part of the FT calcium-dependent antibiotic (CDA) biosynthetic cluster FT from Streptomyces coelicolor. CDA is a peptide antibiotic FT which is synthesised non-ribosomally by a putative FT multifunctional peptide synthetase enzyme. This partial CDS FT encodes the N-terminus of a subunit of this enzyme FT suspected to be responsible for the addition of 2 amino FT acids to the peptide antibiotic. This ORF overlaps the FT upstream (cdaPSII) by one base indicating possible FT translational coupling. Contains Pfam match to entry FT PF00668 DUF4, Domain of unknown function." FT /note="SCE29.01, partial CDS, cdaPS3, CDA peptide FT synthetase III, len: >332aa; Constitutes the the majority FT of cdaPS3, CDA peptide synthetase III, part of the FT calcium-dependent antibiotic (CDA) biosynthetic cluster FT from Streptomyces coelicolor. CDA is a peptide antibiotic FT which is synthesised non-ribosomally by a putative FT multifunctional peptide synthetase enzyme. This partial CDS FT encodes a subunit of this enzyme suspected to be FT responsible for the addition of 2 amino acids to the FT peptide antibiotic. This ORF overlaps the upstream FT (cdaPSII) by one base indicating possible translational FT coupling. Contains two Pfam matches to entry PF00501 FT AMP-binding, AMP-binding enzyme, a Pfam match to entry FT PF00668 DUF4, Domain of unknown function, a Pfam match to FT entry PF00975 Thioesterase, Thioesterase domain and two FT Pfam matches to entry PF00550 pp-binding, FT Phosphopantetheine attachment site. Each PF00501 contains a FT Prosite match PS00455 Putative AMP-binding domain FT signature. Each PF00550 contains a Prosite match PS00012 FT Phosphopantetheine attachment site." FT /db_xref="GOA:Q8CJX2" FT /db_xref="HSSP:1AMU" FT /db_xref="InterPro:IPR010071" FT /db_xref="UniProtKB/TrEMBL:Q8CJX2" FT /protein_id="CAD55498.1" FT /translation="MAKSGLEDILPLSPLQEGMLFHNLFDEEELDAYNVQVFIDLEGGT FT DPERLRRAGQALLERHANLRAAFRHEGLKRPVQLIPRRVVLPWGEEDLSGVAEPEREAA FT AERVAERDRWTRFDLSRPPLIRFTLVRLGPARHRLLLTLHHILADGWSMPILLRELMTL FT YTVHGDGTALPRVRPYRDYLGWLGGRDRDAARQAWTEAFAGLDAPSIVAPGRGALTAAP FT ERIDFSEDEAASAALTRFARSNGLTVNTVIQGCWGLVLSHLTGRDDVVFGVTVSGRPPE FT LPGIDTMVGLFMNTLPLRVRLRPAETLTGFLRRLQGEQARLIDHQWVGLAEIQRWAGSG FT ELFDTAMVFENYPLNSSRGRPPGAAPDADLPTVLGVRSKDQMHYPLGLLALPRETLRFS FT LGYLPQVFDPARVEAVIAAFRRALRTVLDAPDTRVGAVALLDPEVRGTVLEKWSGSDDV FT RPAERFTDLFEEQVARTPGKTALIAPDGRLTYAELDAAANRLARRLVELGVGPERHVAV FT AVGRRTELVVGMLAVLKAGGAYVPVDPEYPPDRIRHMIQDADPALVLTTSDVDDRIGEE FT CCGPLTFVMDDPNTGTSLGRHSGTALTDADRAAPLLPGHPAYVIYTSGTTGRPKGVVVE FT HRALSAFVRHCRSSQAPDISGLSVMQASASFDQSVGSLHAPLISGGCVRLTDLRALAET FT AGSEPGFHRATFMKGTPSHLALLATMPPEVAPSGTLTLGGEELRGEILAPWREAAGDVT FT VVNVYGPTEATGHCLEHWIAPDRTVEPGPVPIGTPHEGVRVYVLDSALRPVAPGLDGEV FT YLAGVQLARGYLGRGGLTAERFTADPFGAPGSRMYRTGDVAHWNEAGELVFAGRADRQV FT KLRGYRIELGEIEAAVAGGPGVRQAAVVLREDRPGDQRLVAYVVPDPGHWDEAAARARL FT ALSLPDFMMPSAFVALDALPLSPNGKLDRAALPAPTYTGRTAGRAPRTPAEEILCDLYA FT EVLSLPGVTVDDDFFDLGGHSLLATRLVSRVRTTLGAELSIRQFFEAPTPAALAVVLAG FT AGRARAALTARPRPERLPLSYAQQRLWFLHLLEGPSPTYNIPTVLRLSGPLRPDALRAA FT LLDVVGRHESLRTTFTEDERGARQVVHPADGVRPVFETAESTEADYEADLARAARHAFD FT LGAEIPVRARLLRLSEREHVLLLLVHHIASDAWSRGPLAQDLTAAYTARCAGDAPAWQP FT LPVQYADYALWQQEILGDDTDPDTLAGRQLAYWKQQLAGLPERLDLPTDRPRPATADHT FT GDRVEFALPADLHTRLTELARATDTTLYMVLQAALATLLTRHGAGEDIPIGTPVAGRTD FT DATDHLVGFFVNTLVLRTDTSGNPTFRDLLTRVRDTDLTAYTHQDLPFERLVEALNPTR FT SLTHHPLFQVVLSLRSTAPRRADGEGAPALPGGLRVSGTGGAAATAAKVDLGFSVTERR FT AADHTPDGVAGVLDFRTDLFDRGTAQGLVDRLVRVLADAAAHPDRPLSRIDVLGPRERH FT RVVEEWNATAKGLAPATLPELFERHVRERPGAEAVVAGDTSLSYAELNARANRLARLLV FT ARGAGPERLVALALPRSAELPVAVLAVAKAGAAYLPLDPAHPAERIAGTLDDAAPVALL FT TTAAVAAGLPDTDVPRLLLDEEPAAGGGEDAADLTDADRLAPLLPGHPAYVIYTSGTTG FT RPKGVTVTHSGLPALLDIFTSQLDVVPGSRVLHHLSPAFDGGFWELAMGLLTGAALVVV FT EPGTVPGPALAALAVRHRVTHAAITPAVLQLIPEGALPAGTTLVVAAETCPPELVARWS FT AGRLMRNSYGPTETTVCATMSAPLAGAAVPPIGRPIADTAGYVLDDALQPVPPGVPGEL FT YVRGPGLARGYLGRPSLTAGRFVACPFGPAGGVMYRTGDLVRHRADGDLEYLGRTDTQV FT KLRGMRVEPAEIEAVTAGLPGVAQAAVLVREDTPGDRRLVGYVVPDAGASVDPGALRQA FT LRGSLPEYMVPAALVVLDALPLTTNGKLDHRALPAPEYRTVEGRSPRTPREEALCRLFA FT EVLGLELVGLDDGFFDLGGHSLLAIRLVERVRAELGEELGVRDLFAAPTVADLAVRLAA FT RGGREPMERLLPLRAAGTARPVFCVHPGSGMSWCYSGLVRHLPPGIPVYGLQAAGLDGD FT GPLPATLQEMAAEYADLVRQTQPEGPYRLLGWSLGGNVAFAMARELRARGQEVELLAFL FT DAYPRRAGAGPEAPLAEVFAHNLRDAGFDVAEEELTGGRFPTARYRAFLNAAGDPMGRL FT DEAELAAVLEVFMNNAALMRGHTPGTYDGDVLVLAAERADGDKLARRGAESWRPHVRGR FT IERVGVDADHLGLVQSDAALAVIGRALAGRLDPATGHAASAAVPETEGVTAMNPSPEPA FT PSPESLDSTEVA" FT misc_feature complement(229433..229533) FT /note="Overlap with Streptomyces coelicolor cosmid StE63." FT misc_feature 229999..231226 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 385.20, E-value 6.6e-112" FT misc_feature 230389..230424 FT /note="PS00455 Putative AMP-binding domain signature." FT misc_feature 231478..231670 FT /note="Pfam match to entry PF00550 pp-binding, FT Phosphopantetheine attachment site, score 78.40, E-value FT 4.6e-20" FT misc_feature 231547..231594 FT /note="PS00012 Phosphopantetheine attachment site." FT misc_feature 231715..232912 FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 335.30, E-value 6.9e-97" FT misc_feature 233221..234412 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 448.70, E-value 5.2e-131" FT misc_feature 233599..233634 FT /note="PS00455 Putative AMP-binding domain signature." FT misc_feature 234664..234856 FT /note="Pfam match to entry PF00550 pp-binding, FT Phosphopantetheine attachment site, score 76.90, E-value FT 1.2e-19" FT misc_feature 234733..234780 FT /note="PS00012 Phosphopantetheine attachment site." FT misc_feature 234922..235651 FT /note="Pfam match to entry PF00975 Thioesterase, FT Thioesterase domain, score 139.00, E-value 8.5e-38" FT CDS 235792..236610 FT /transl_table=11 FT /gene="SCO3233" FT /gene_synonym="SCE29.0" FT /product="putative hydrolase" FT /note="SCE29.02, probable hydrolase, len: 272 aa; similar FT to many e.g. TR:O52809 (EMBL:AJ223998) from the vancomycin FT biosynthesis cluster of Amycolatopsis orientalis (276 aa) FT fasta scores; opt: 892, z-score: 1028.9, E(): 0, (50.9% FT identity in 271 aa overlap) and TR:O67982 (EMBL:AF003947) FT PcaL; single polypeptide combining 3-oxoadipate FT enol-lactone hydrolyzing and 4-carboxymuconolactone FT decarboxylating activityfrom Rhodococcus opacus (400 aa) FT fasta scores; opt: 288, z-score: 335.4, E(): 2.3e-11, FT (32.0% identity in 256 aa overlap). Contains Pfam match to FT entry PF00561 abhydrolase, alpha/beta hydrolase fold, score FT 77.80, E-value 2.2e-19." FT /db_xref="GOA:Q9Z4Z8" FT /db_xref="InterPro:IPR000639" FT /db_xref="UniProtKB/TrEMBL:Q9Z4Z8" FT /protein_id="CAB38877.1" FT /translation="MPVLTVNGIRINYYDDAPPAGAQNAPAVLLVMGSGGSGRAWHLHQ FT VPALVAAGFRVISFDNRGIAPSEECPGGFGIDDLVADTAALVEELRLGPCRVAGISMGA FT HIAQELALSRPDLVDRLVLMATRARPDALREALCRAEMELYDQGIRLPAAYEAVVQAMQ FT NLSPRTLDNDVQARDWLDVLELTRRSGAGYRAQLGVRVDGDRREAYRGIRAATRVVAFQ FT DDLIAPPHLGREVADAIPGAEYELVPDCGHYGYLESPDAVNKSLVEFLRR" FT misc_feature 235951..236601 FT /note="Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold, score 77.80, E-value 2.2e-19." FT CDS 236622..237524 FT /transl_table=11 FT /gene="SCO3234" FT /gene_synonym="SCE29.03" FT /product="putative phosphotransferase" FT /note="SCE29.03, possible phosphotransferase, len: 300 aa; FT weak similarity to TR:P72441 (EMBL:U70376) spectinomycin FT phosphotransferase from spectinomycin producer Streptomyces FT flavopersicus (330 aa) fasta scores; opt: 145, z-score: FT 177.0, E(): 0.015, (25.3% identity in 261 aa overlap)." FT /db_xref="GOA:Q9Z4Z7" FT /db_xref="InterPro:IPR002575" FT /db_xref="UniProtKB/Swiss-Prot:Q9Z4Z7" FT /protein_id="CAB38878.1" FT /translation="MKTESDVQTGAPTAADGALIALAREVCPGFAPGEVVYRSRTSLVV FT GGELDGVEALAKVRTPDWRRQCLREIDTYDLFDAVPPPVPVPRRFASDRERAVLVMERL FT TGEVLAPDRFPVTPVSREDLAGVLEAVERLRHWRPAAAGAWAVDYRGMLEGVHAQGVFD FT DGHWADLLRLLELSGAPREFGHGDLVLANVVRSRGRQVLIDWASSALYLPGLDLAQLWM FT LLGDVPGARARIEVEVADRADDRDGMMPFLVNLTLLLYRERRAHRRFTDDASRARAVGL FT DAAWELTRHRVRQCLATAG" FT stem_loop 237529..237591 FT /note="Possible stem loop with 8 base loop." FT CDS complement(237600..239447) FT /transl_table=11 FT /gene="SCO3235" FT /gene_synonym="SCE29.04c" FT /product="putative ABC transporter" FT /note="SCE29.04c, probable ABC transporter, len: 615aa; FT similar to many eg. TR:D1035364 (EMBL:AB019513) ABC FT transporter from Streptomyces coelicolor fasta scores; opt: FT 783, z-score: 794.3, E(): 0, (42.8% identity in 596 aa FT overlap). C-terminal half contains Pfam match to entry FT PF00005 ABC_tran, ABC transporter (score 184.50, E-value FT 1.7e-51) which itself contains Prosite matches to PS00211 FT ABC transporters family signature and PS00017 FT ATP/GTP-binding site motif A (P-loop). N-terminal half FT contains Pfam match to entry PF00664 ABC_membrane, ABC FT transporter transmembrane region., score 129.80, E-value FT 4.9e-35. Contains probable transmembrane hydrophobic FT regions." FT /db_xref="GOA:Q9Z4Z6" FT /db_xref="HSSP:1MV5" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9Z4Z6" FT /protein_id="CAB38879.1" FT /translation="MTSTQTRERPPARKTGAKNAPEPGPPAPPVRKVGLRSLFPYLQGY FT WPTLGIVAVLSLVVTLLTLSQPVLTRDVLADIEADRPVGRLVALLIGVLVVVAVLGGVR FT DYLLQRAAEGLVLTARRRLVARLLRLPITEYDQRRTGDMLSRVGADTTMLRAVVTSGLF FT DTVTNVVMVGGSALMMCLIDPTLFAATALGLGLGVLAVVGLSRRVRGASRDAQDRIGEM FT TSAVERAISAVRTIRASGAEEREGKAVDGYAQQAYHAGMRIARLQAMINPITSTTIQVA FT FLVVLGLGGARVASGAIQVGDMVAFVLFLFMLWFPLGRALTAYSRLQSGLGALQRIEEM FT VDLPQETDAVAGPLTVRERTRPGTEPADAEPRPPAIEFEGVSFGYGDGETVLRDVSLAV FT PRGTRTALVGPSGAGKSTLLSLVERFYDVTSGTVRVGGTDVRDLPRRELRGRLGYVEQS FT APVLAGTVRDNLSLAAPDATDDDMREVLRSVNLMGVIERAPQGLDTEVGEGGVLLSGGE FT RQRLALARTFLAAPPIMLLDEATSNLDARNEALMREAIGTVTADRTLLVVAHRLSTVVD FT SDQIVVLEHGRVVAAGRHEELTGTSPLYRELASHQLLIQ" FT misc_feature complement(237690..238244) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 184.50, E-value 1.7e-51" FT misc_feature complement(237867..237911) FT /note="PS00211 ABC transporters family signature." FT misc_feature complement(238200..238223) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature complement(238497..239303) FT /note="Pfam match to entry PF00664 ABC_membrane, ABC FT transporter transmembrane region., score 129.80, E-value FT 4.9e-35." FT CDS complement(239487..240488) FT /transl_table=11 FT /gene="SCO3236" FT /gene_synonym="SCE29.05c" FT /product="putative oxygenase" FT /note="SCE29.05c, possible oxygenase, len: 333 aa; similar FT to TR:Q05581 (EMBL:L06213) clavaminate synthase I, an FT alpha-ketoglutarate-dependent oxygenase central to the FT biosynthesis of clavulanic acid, a potent inhibitor of FT beta-lactamases (324 aa) fasta scores; opt: 498, z-score: FT 571.8, E(): 1.5e-24, (34.3% identity in 283 aa overlap)." FT /db_xref="GOA:Q9Z4Z5" FT /db_xref="InterPro:IPR003819" FT /db_xref="PDB:2OG5" FT /db_xref="UniProtKB/Swiss-Prot:Q9Z4Z5" FT /protein_id="CAB38880.1" FT /translation="MAANAAGPASRYDVTLDQSDAELVEEIAWKLATQATGRPDDAEWV FT EAARNAWHAWPATLRRDLAGFRRDSGPDGAIVLRGLPVDSMGLPPTPRVNGSVQREASL FT GAAVLLMTACGLGDPGAFLPEKNGALVQDVVPVPGMEEFQGNAGSTLLTFHNENAFHEH FT RPDFVMLLCLRADPTGRAGLRTACVRRVLPLLSDSTVDALWAPEFRTAPPPSFQLSGPE FT EAPAPVLLGDRSDPDLRVDLAATEPVTERAAEALRELQAHFDATAVTHRLLPGELAIVD FT NRVTVHGRTEFTPRYDGTDRWLQRTFVLTDLRRSRAMRPADGYVLGAAPQPA" FT CDS complement(240546..241934) FT /transl_table=11 FT /gene="SCO3237" FT /gene_synonym="SCE29.06c" FT /product="conserved hypothetical protein" FT /note="SCE29.06c, unknown, len: 462 aa; similar to FT TR:O69954 (EMBL:AL023862) hypothetical protein from FT Streptomyces coelicolor (465 aa) fasta scores; opt: 2210, FT z-score: 2646.8, E(): 0, (70.8% identity in 452 aa FT overlap)." FT /db_xref="GOA:Q9Z4Z4" FT /db_xref="InterPro:IPR017849" FT /db_xref="UniProtKB/TrEMBL:Q9Z4Z4" FT /protein_id="CAB38881.1" FT /translation="MLDVVGLTPRLLAHMPRLSALRDAGTGARLDTVLPAVTCSVQSTL FT LTGRPPAEHGVVGNGWYFRDLGEVLLWRQHNRLVGGEKVWQAARALHPGYTVANVCWWY FT AMGADVDWTVTPRPVYYADGRKEPDCYTHPASLHDELTGRLGPFPLFHYWGPTADLASS FT RWIVDAARHLHRAHKPDLNLVYVPHLDYDLQRFGPDSRRARRAAAELDRTLAPLLDEAR FT RDGVTVVVLSEYGITPVSRPVDINRALRRAGLLAVHTQDGMEYLDPWTSRAFAVADHQV FT AHVYVRDAADLPRVEELLHGLDGVAEVLGEAGKKEHGLDHERAGELVAVARPEAWFTYY FT YWLDDARAPDFARTVEIHRKPGYDPAELGFDHHAPAKARLRAAAALARKKLGLRYTMNV FT VPLDGSRVRGSHGRLPGRPEDAPVLLVSDPDAPLGELVAATEVKELLLSLAGISPHAHS FT IRGR" FT CDS complement(241946..243106) FT /transl_table=11 FT /gene="SCO3238" FT /gene_synonym="SCE29.07c" FT /product="hypothetical protein" FT /note="SCE29.07c, unknown, len: 386 aa; similar to FT TR:O69953 (EMBL:AL023862) hypothetical protein from FT Streptomyces coelicolor (391 aa) fasta scores; opt: 1396, FT z-score: 1559.7, E(): 0, (58.6% identity in 389 aa FT overlap). Contains PS00730 AP endonucleases family 2 FT signature 2." FT /db_xref="GOA:Q9Z4Z3" FT /db_xref="InterPro:IPR012307" FT /db_xref="UniProtKB/TrEMBL:Q9Z4Z3" FT /protein_id="CAB38882.1" FT /translation="MRLRHRDGTTVHLAYCTNVHAAEDLDGVLAQLARYGEPVRERLGA FT DRIGLGLWLAAPVVTALAADRSALDLLRKELDLRGIEVVTLNAFPYAGFHAPTVKKAVY FT RPDWTERPRLDHTLACARVLAELLPPDAARGSVSTLPLAWRTPWTPRRDDLARRHLDLL FT SQGLAALNADTGRTVRVGFEPEPGCLIETTGQAVARLAGADPERLGVCVDTCHLAVAFE FT EPGPALTRLAAALPVVKTQASCAVHADRPADPAARAALAAFAERRFLHQTRQAAPGGPS FT AVDDLPEALGGALNGDAAWRIHYHVPVQRDLPPPLRSTRPELVAALTTLLGGPTALTDH FT VEVETYTWPVLPGAPDGGGLVDGIAGELAWTRSALTALGLTEESTP" FT misc_feature complement(242459..242482) FT /note="PS00730 AP endonucleases family 2 signature 2." FT CDS complement(243113..243982) FT /transl_table=11 FT /gene="SCO3239" FT /gene_synonym="SCE29.08c" FT /product="conserved hypothetical protein" FT /note="SCE29.08c, unknown, len: 289 aa; similar to FT TR:O69952 (EMBL:AL023862) hypothetical protein from FT Streptomyces coelicolor (282 aa) fasta scores; opt: 1391, FT z-score: 1679.9, E(): 0, (72.3% identity in 285 aa FT overlap)." FT /db_xref="GOA:Q9Z4Z2" FT /db_xref="InterPro:IPR012022" FT /db_xref="UniProtKB/TrEMBL:Q9Z4Z2" FT /protein_id="CAB38883.1" FT /translation="MTRIFDPHIHMTSRTTDDYEAMAAAGVRALVEPAFWLGQPRTGVS FT SFTDYFDALLGWEPYRAEQFGIRHHCALALNPKEANDPRLAGVLDVLPDYLVRDRVVAV FT GEVGYDAMTPQEDKAFTVQLELAVRHALPVLVHTPHRDKANGTRRTLDVVRESGIDPGL FT VVVDHLNEVTVRAVADSGCWMGFSIYPDTKMSEDRMVALLREYGTARILVNSAADWGRS FT DPLKTRRTADAMRAAGFGEDDVDQVLWRNPVAFYGQSGRLELDGPEGAEASGVRAEFEG FT SSIRRGER" FT CDS complement(243979..244689) FT /transl_table=11 FT /gene="SCO3240" FT /gene_synonym="SCE29.09c" FT /product="conserved hypothetical protein" FT /note="SCE29.09c, unknown, len: 236 aa; similar to FT TR:O69951 (EMBL:AL023862) hypothetical protein from FT Streptomyces coelicolor (245 aa) fasta scores; opt: 416, FT z-score: 464.9, E(): 1.4e-18, (45.5% identity in 220 aa FT overlap)." FT /db_xref="UniProtKB/TrEMBL:Q9Z4Z1" FT /protein_id="CAB38884.1" FT /translation="MNPGGDGPRSLPDALAGALDRALAPDAAAWLEQACAAVRCEPGEV FT EGTFAVAARRCGRGALDAGAEAGAGADAGTGLGAGWSVDDAARVLLLAALPVRGAALAA FT VVSRLYRIGGGPERRAVLRSLSLLEAAGDLGDLGLPLVEDALRCNDPRLIAAAVGPYGA FT RRLGAHAFRQAVLKCVFVGVPLDLVAALDARADAELDRMMADFAAERRAAGRALPPDVA FT AYLHTHRVSTEATA" FT CDS complement(244686..245558) FT /transl_table=11 FT /gene="SCO3241" FT /gene_synonym="SCE29.10c" FT /product="putaive isomerase" FT /note="SCE29.10c, possible isomerase, len: 290 aa; similar FT to TR:O69950 (EMBL:AL023862) hypothetical protein from FT Streptomyces coelicolor (315 aa) fasta scores; opt: 1116, FT z-score: 1331.4, E(): 0, (62.5% identity in 283 aa FT overlap). Also similar to SW:XYLA_STRDI xylose isomerase FT from Streptomyces diastaticus (388 aa) fasta scores; opt: FT 122, z-score: 148.8, E(): 0.56,25.0% identity in 296 aa FT overlap." FT /db_xref="GOA:Q9Z4Z0" FT /db_xref="InterPro:IPR013022" FT /db_xref="UniProtKB/TrEMBL:Q9Z4Z0" FT /protein_id="CAB38885.1" FT /translation="MSAGTRFGYGTNGFGDHPLEDALAVLADLGYEGVGLTLDPRHLDP FT FADDLPHRLRRLAARLDRLGLAVVVETGGRYVLDPWRKHQPVLMSAEGAGRRVDLLLRA FT VRIAADLGAEAVSFWSGAAPADTPRQVVWDRLLAGCGTVVEAAARAGVVLGFEPEPGMF FT VDTLDAYDELCRRLGGPHPLGLTLDIGHCRCLEPQPVADCVRRVADRLVNVQIEDMRRG FT THEHLEFGSGEIDFPPVLSALAATGYRGLVSVELPRHSHAAPEVARRSLDFLRAADAGA FT RPATRGAAA" FT CDS complement(245555..246430) FT /transl_table=11 FT /gene="SCO3242" FT /gene_synonym="SCE29.11c" FT /product="puitative transferase" FT /note="SCE29.11c, possible transferase, len: 291 aa; FT similar to TR:O69949 (EMBL:AL023862) hypothetical protein FT from Streptomyces coelicolor (363 aa) fasta scores; opt: FT 666, z-score: 682.9, E(): 9.9e-31, (51.3% identity in 312 FT aa overlap). Also similar to SW:UBIA_ECOLI FT 4-hydroxybenzoate octaprenyl transferase from Escherichia FT coli (290 aa) fasta scores; opt: 137, z-score: 150.2, E(): FT 0.47, (31.8% identity in 110 aa overlap)." FT /db_xref="GOA:Q9Z4Y9" FT /db_xref="InterPro:IPR000537" FT /db_xref="UniProtKB/TrEMBL:Q9Z4Y9" FT /protein_id="CAB38886.1" FT /translation="MSALPRVHDLARLVRAPAALSVPGDVLAGAAAARRPLGPGLLGMT FT ASSVCLYWAGMALNDYADRDLDAVERPERPVPSGAVSPAAARAVGCGLTAAGLGLAALS FT RGRRGLATALPLAGVVWAYDLVLKPTPAGAAAMAAARALNVLGGAGPGGLRRALPAAAT FT VALHTGMVTRLSRYEVSGAPRAVPRQSLAVGGAVGAAVLLRGRRRPARDRVLAAGLTAV FT YAYGGAAAQLAAARSPAAPQVRRAVAAGIHALIPLQAALTATAGRGAAGAALACALPWA FT RRLGRKVSPT" FT CDS complement(246427..247593) FT /transl_table=11 FT /gene="SCO3243" FT /gene_synonym="SCE29.12c" FT /product="putative myo-inositol phosphate synthase" FT /note="SCE29.12c, possible myo-inositol phosphate synthase, FT len: 388 aa; similar to many e.g. TR:O69948 (EMBL:AL023862) FT from Streptomyces coelicolor (417 aa) fasta scores; opt: FT 955, z-score: 1034.1, E(): 0, (60.3% identity in 380 aa FT overlap) and SW:INO1_CITPA myo-inositol phosphate synthase FT from Citrus paradisi (grapefruit) fasta scores; opt: 323, FT z-score: 352.1, E(): 2.6e-12, (26.9% identity in 364 aa FT overlap)." FT /db_xref="GOA:Q9Z4Y8" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9Z4Y8" FT /protein_id="CAB38887.1" FT /translation="MRTGIWLVGARGSVATTTVVGAAALRAGLVPATGCVSALEAFDGV FT PLPGFDELVFGGHDVVGTGLVKRAEQLAEAGVVPRGLPGVLTAELDAADAEIRPAPPGT FT EEGGDGTPDQASAAGAIVADLTGFRERLGLDRVVVVNVSSTQPPAVPHPAHASAAALRE FT ALARGERPLPVSSLYAYAALRAGCAFVDFTPSTGARLPALDELAREQGLPYAGSDGKTG FT ETLVKSVLAPMFARRALRVRSWSGTNLLGGGDGATLADPERVVSKNASKGLVLEAELGH FT AVEGGVHIHHVPDLGEWKTAWDHVTFEGFLGARMTLQFTWQGCDSSLAAPLVLDLARFM FT ALAHRAGVAGPVPELGFFFKDPVGSAEHDLAAQYASLAAWARSVGAPA" FT CDS complement(247643..248440) FT /transl_table=11 FT /gene="SCO3244" FT /gene_synonym="SCE29.13c" FT /product="putative secreted protein" FT /note="SCE29.13c, putative secreted protein, len: 265 aa; FT similar to SW:Y0BO_MYCTU hypothetical protein from FT Mycobacterium tuberculosis (529 aa) fasta scores; opt: 116, FT z-score: 133.8, E(): 3.8, (38.2% identity in 76 aa FT overlap). Contains possible N-terminal region signal FT peptide sequence" FT /db_xref="InterPro:IPR017909" FT /db_xref="UniProtKB/TrEMBL:Q9Z4Y7" FT /protein_id="CAB38888.1" FT /translation="MSNHLDRRRLMTTALGGAAAVGLGAGAGLLGAAPAGAAERPVTPH FT RGHDDFPDVPGMLGDRRANELWYMFDETTLYNVGPELEQAFTDIETALGDGWERAIFDA FT WMAMAATSDYPNNFIEYVTPIKGPLQVLSKAQLGVFDTYYRPYGHGIVGAFADFAQGVL FT NDPRRERPVHTMNGNPPPGYHIWFIFMRSMMLLDISRHRWERMAPINAMAWAIQTIAKP FT SQFEVKEPLPRRVVAREAAKWLPRSVHRLDRDFLSYPLPEGMS" FT CDS complement(248508..249770) FT /transl_table=11 FT /gene="SCO3245" FT /gene_synonym="SCE29.14c" FT /product="putative salicylate hydroxylase (putative FT secreted protein)" FT /note="SCE29.14c, possible salicylate hydroxylase (putative FT secreted protein), len: 420 aa; similar to many e.g. FT TR:P96555 (EMBL:AB000564) salicylate hydroxylase from FT Sphingomonas sp. AJ1 (395 aa) fasta scores; opt: 830, FT z-score: 827.2, E(): 0, (41.9% identity in 320 aa overlap) FT and TR:G4104775 (EMBL:AF039534) salicylate hydroxylase from FT Pseudomonas stutzeri strain AN10 (389 aa) fasta scores; FT opt: 707, z-score: 706.0, E(): 5.1e-32, (34.7% identity in FT 401 aa overlap). Contains Pfam match to entry PF01360 FT Monooxygenase, Monooxygenase, score 91.00, E-value 2.4e-23. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="GOA:Q9Z4Y6" FT /db_xref="InterPro:IPR003042" FT /db_xref="UniProtKB/TrEMBL:Q9Z4Y6" FT /protein_id="CAB38889.1" FT /translation="MPKLRIAVVGGGIGGLAAALALTRKGHEVRVYEQAPELREAGVGM FT HLGPNGSRLLERWGLGERLRALGVRPAGMEVRDWSHGGTLVRQPMGEEWLAEFGAPYYT FT IHRADLHTMLAESLPSGTVRAGHRLERFTETGGGVRLEFADGSTAGADVLIGADGAHSV FT VRRTLAGPDTAVFSGQSAFRGVVARDQVPGLPGDTLLVWAGPDARMLVYPVRGGRFLTF FT VAVVPDPRWRLESWSAPGDLDELAARFDGWNTDVKSLVAAVRESRRWALYDREPLARWS FT AGAVTLLGDAAHPMLPHHGQGVSQAVEDAAVLAHCLDAPTGPDPSASVSAAAAASAPAA FT AAASAPAARRAIAAALDAYEGVRRPHTTRVQLGSRGGGSQRLRPDEDGTESTGTMSSLV FT EDVSWIQRHDAEAGLPPLPPP" FT misc_feature complement(248646..249323) FT /note="Pfam match to entry PF01360 Monooxygenase, FT Monooxygenase, score 91.00, E-value 2.4e-23." FT CDS complement(249817..250809) FT /transl_table=11 FT /gene="SCO3246" FT /gene_synonym="SCE29.15c" FT /gene_synonym="fabH4" FT /product="putative 3-oxoacyl-[acyl carrier protein] FT synthase III" FT /note="SCE29.15c, fabH4, probable 3-oxoacyl-[acyl carrier FT protein] synthase III, len: aa; similar to many eg. FT SW:FABH_ECOLI 3-oxoacyl-[acyl carrier protein] synthase FT III, FabH, from Escherichia coli (317 aa) fasta scores; FT opt: 765, z-score: 862.6, E(): 0, (40.8% identity in 314 aa FT overlap). Also similar to two from Streptomyces coelicolor FT - TR:O54151 (EMBL:AL021409) (335 aa) fasta scores; opt: FT 694, z-score: 782.9, E(): 0, (53.5% identity in 331 aa FT overlap) and TR:E1359140 (EMBL:AL034443) (316 aa) fasta FT scores; opt: 685, z-score: 773.2, E(): 0, (40.6% identity FT in 313 aa overlap)." FT /db_xref="GOA:Q9Z4Y5" FT /db_xref="HSSP:1HNK" FT /db_xref="InterPro:IPR016038" FT /db_xref="UniProtKB/Swiss-Prot:Q9Z4Y5" FT /protein_id="CAB38890.1" FT /translation="MSAARGGRAGAVVTGVGTCLPETVVDNDEVSRHLDTDHAWIHSRT FT GIERRRRVSPGTTTGDLAVTAGAAALKSAGRDDCDLVLLATTTPDRRCPATAPRVASRL FT GLRAAAAFDLSAVCSGFVYGLSVASAMITAGTCDRALVIGADVYSSIVDPDDRGTAVVF FT GDGAGAVLLERGDTGDPGAVLHTELGSDGTGDELITIPPDGAYLTMRGSDVYTRAVTTM FT AESARSTAAHAGWDLADVDAFVGHQANLRILTSVAKRLRLPPERVVSNIADVANTAAAS FT IPLALADAAAQGRIGSGDRLLLTAFGGGLTWGSAAVVWSGAEPVQDQRS" FT CDS complement(250806..252608) FT /transl_table=11 FT /gene="SCO3247" FT /gene_synonym="SCE29.16c" FT /product="putative acyl CoA oxidase" FT /note="SCE29.16c, possible acyl CoA oxidase, len: 600 aa; FT similar to many acyl CoA oxidases, especially from FT eukaryotes e.g. SW:CAOP_RAT acyl CoA oxidase from Rattus FT norvegicus (rat) (661 aa) fasta scores; opt: 462, z-score: FT 477.6, E(): 2.7e-19, (27.8% identity in 425 aa overlap). FT Contains PS00017 ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q9Z4Y4" FT /db_xref="InterPro:IPR006091" FT /db_xref="UniProtKB/TrEMBL:Q9Z4Y4" FT /protein_id="CAB38891.1" FT /translation="MTQREEELARVLSGPEFATIRPDDLSVLDYSLLTLRRARLLNGAG FT FAANSLWLGRGDSARFPEFLRTMGWIGAYDLSLLNVLVSHQIAGDALLSHGGPEQLDAW FT AGEIDAMERMYCFAGSELLAGSDLKRVRTTAVYDPHGRSLVLNTPRPADSKVWTGNSLH FT TGDVAMVLARLEVGGRDEGHHWLRVPLREAGAVLPGVRIGRAEPKGGVTANQTGVLTFT FT DHRLPLSALMNRWASIDEDGTYRSPLPRHRRFEECLATFTHERLFPSVGAAYAQLLACT FT ITTRFAAVKQTFGRPLIGHEHYRMRLSAAVGRSLAARHAMTALAEVAVARSAEGAPARD FT QVLHALISCGKSGCTGDARQTLAETRELCGGLGYHDANQIAPLLHDYEIAVTFGGDNTV FT LGYQATRFALRHREDFDRVLDEAVAGAGRLDAVRVLRAVCDVLLDRVERDGAGEASAQW FT SRAVHQTLAIGHWARQASTPLSERLLAQYAAVCVLEHALAALRAGILDQDALLGFEAAR FT HEAAGAPLDADALLRELAVPEGLISAPIAHPDFAERHAAAAHAGTAAAHAGTVPSPGTG FT PSPGTGPAPGTVQAPGTVQAGVRP" FT misc_feature complement(251553..251576) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS complement(252658..253878) FT /transl_table=11 FT /gene="SCO3248" FT /gene_synonym="SCE29.17c" FT /gene_synonym="fabF3" FT /product="putative 3-oxoacyl-[acyl carrier protein] FT synthase II" FT /note="SCE29.17c, fabF3, probable 3-oxoacyl-[acyl carrier FT protein] synthase II, len: 406 aa; similar to many e.g. FT TR:O54149 (EMBL:AL021409) 3-oxoacyl acyl carrier protein FT synthase II from the Red cluster of Streptomyces coelicolor FT (407 aa) fasta scores; opt: 1217, z-score: 1314.2, E(): 0, FT (50.1% identity in 407 aa overlap) and SW:FABF_ECOLI FT 3-oxoacyl-[acyl carrier protein] synthase II FabF, from FT Escherichia coli (412 aa) fasta scores; opt: 843, z-score: FT 912.2, E(): 0, (35.4% identity in 404 aa overlap). Contains FT Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl FT synthase, score 92.60, E-value 7.7e-24 and Prosite match FT PS00606 Beta-ketoacyl synthases active site." FT /db_xref="GOA:Q9Z4Y3" FT /db_xref="HSSP:1E5M" FT /db_xref="InterPro:IPR000408" FT /db_xref="UniProtKB/TrEMBL:Q9Z4Y3" FT /protein_id="CAB38892.1" FT /translation="MTEGPAAITGVGLVTPAGTDADSTWEAMCAARSLEGGDPEPLAGT FT GAWHSLRVPALRPGQLTGRGTARTDPFIRFALVAVAEALAQSGLDPDSWDGSRVGVVVG FT SAFGGVTTHDEQHRRLERQGAAMVSPYLHPRALINMAAGTIGARYGITGPGHTVAAACA FT SGASAFGLGKTLLDAGVCDTVVVCGTDAAVTPLVVSGFARMGALSEQKATDASRPFGAD FT RDGFVMSEGAAAVVMEKPAKARARGAEVLGRLLGHADTSDAHHPTAPRPDGAGAAAAVE FT RALAAARMSVRNVTTVNAHGTSTPQNDLTEARLIARLFPHGPSVTANKGLLGHTLGAAG FT AIEAVLTLRSLRTGVLPPIAHTERADPGLPELDLVLGGVRRHDGNVAVSTSFGFGGSNC FT ALVLDAG" FT misc_feature complement(252661..253863) FT /note="Pfam match to entry PF00109 ketoacyl-synt, FT Beta-ketoacyl synthase, score 92.60, E-value 7.7e-24." FT misc_feature complement(253372..253422) FT /note="PS00606 Beta-ketoacyl synthases active site." FT CDS complement(253875..254120) FT /transl_table=11 FT /gene="SCO3249" FT /gene_synonym="SCE29.18c" FT /product="putative acyl carrier protein" FT /note="SCE29.18c, probable acyl carrier protein, len: 81 FT aa; member of a large family including SW:ACP_HELPY acyl FT carrier protein from Helicobacter pylori (78 aa) fasta FT scores; opt: 121, z-score: 179.0, E(): 0.012, (37.5% FT identity in 64 aa overlap). Contains Pfam match to entry FT PF00550 pp-binding, Phosphopantetheine attachment site, FT score 31.20, E-value 5.3e-07." FT /db_xref="GOA:Q9Z4Y2" FT /db_xref="InterPro:IPR009081" FT /db_xref="UniProtKB/TrEMBL:Q9Z4Y2" FT /protein_id="CAB38893.1" FT /translation="MSTDPKSVVHGILAEDLEVDPAEITDGASLRNLELDSLAVAELIV FT RIKEETGVDLSGDETRIADLTVGEVVLLAGSGLEAA" FT misc_feature complement(253944..254102) FT /note="Pfam match to entry PF00550 pp-binding, FT Phosphopantetheine attachment site, score 31.20, E-value FT 5.3e-07." FT tRNA 254409..254484 FT /note="tRNA Arg anticodon CCT, Cove score 77.93" FT CDS complement(254553..255707) FT /transl_table=11 FT /gene="SCO3250" FT /gene_synonym="SCE29.19c" FT /product="putative integrase" FT /note="SCE29.19c, probable integrase, len: 384aa; similar FT to many eg. SW:INTR_STRAM integrase from the integrated FT conjugative pSAM plasmid of Streptomyces ambofaciens (388 FT aa) fasta scores; opt: 445, z-score: 549.1, E(): 2.8e-23, FT (26.8% identity in 392 aa overlap). Contains Pfam match to FT entry PF00589 Phage_integrase, 'Phage' integrase family, FT score 88.00, E-value 1.9e-22." FT /db_xref="GOA:Q9Z4Y1" FT /db_xref="InterPro:IPR002104" FT /db_xref="UniProtKB/TrEMBL:Q9Z4Y1" FT /protein_id="CAB38894.1" FT /translation="MAGPRKRNPNGAGTITKRKDGRYQCAVYVLQPDGTRARKFAYGKT FT WAECDVKRRELLAKVDQGVPVPTKSAKLSEWMPYWLDNVIKPRRKLSTYDKYEAHVRLY FT LVPLLGAKRLESLGVADVRRFLVRLEKETTAATAKESHRVLRSALTSACREELITRNVA FT KLVEPPRTDSRELKPWTLDETLDFLAASRKDPLYAAFVLAIAMGLRRGEIIGLRWSDLD FT LDNRVLYVRQQTQRRRGVLYDDDPKSRRRRAVPLPALCIAPLRWHRMRQAAARIKAGEQ FT WQESGYVFTTRTGRQVEPRNVYRSFTRVAESAGLRVIRLHDARHGTATLLTAAGVAPRV FT VMEILGHSQISITMDVYTHVVQDTQREAMSHMDRLLRKRRPDRG" FT misc_feature complement(254607..255215) FT /note="Pfam match to entry PF00589 Phage_integrase, 'Phage' FT integrase family, score 88.00, E-value 1.9e-22." FT CDS complement(255707..255907) FT /transl_table=11 FT /gene="SCO3251" FT /gene_synonym="SCE39.01c" FT /gene_synonym="SCE29.20c" FT /product="putative excisionase" FT /note="SCE39.01c, partial CDS, probable excisionase, len: FT >33 aa; similar to others eg. TR:E1286473 (EMBL:AJ005260) FT Xis, excisionase fron the integrated conjugative plasmid FT pSAM2 of Streptomyces ambofaciens (62 aa) fasta scores; FT opt: 143, z-score: 280.9, E(): 2.4e-08, (96.0% identity in FT 25 aa overlap)." FT /note="SCE29.20c, probable excisionase, len: 66 aa; highly FT similar to SW:VXIS_STRAM excisionase from the integrated FT conjugative pSAM plasmid of Streptomyces ambofaciens (62 FT aa) fasta scores; opt: 290, z-score: 444.1, E(): 2e-17, FT (80.7% identity in 57 aa overlap)." FT /db_xref="GOA:Q9Z4Y0" FT /db_xref="InterPro:IPR010093" FT /db_xref="UniProtKB/TrEMBL:Q9Z4Y0" FT /protein_id="CAB38895.1" FT /translation="MTAATAVATAELLTVPEVMARLKVGRSKVYDLIRSRRLVSIKIDG FT ARRIPAAAVRDFVLGQIEEAA" FT CDS complement(255904..257304) FT /transl_table=11 FT /gene="SCO3252" FT /gene_synonym="repSA" FT /gene_synonym="SCE39.02c" FT /product="replication initiator protein" FT /note="SCE39.02c, repSA, replication initiator protein, FT len: 466 aa; highly similar to TR:E1288125 (EMBL:AJ005260) FT RepSA, replication initiator protein from the integrated FT conjugative plasmid pSAM2 of Streptomyces ambofaciens (459 FT aa) fasta scores; opt: 2822, z-score: 3195.3, E(): 0, FT (89.5% identity in 455 aa overlap) and TR:E1355655 FT (EMBL:AL034355) putative plasmid replication initiator FT protein from Streptomyces coelicolor (452 aa) fasta scores; FT opt: 732, z-score: 831.1, E(): 0, (45.8% identity in 459 aa FT overlap)." FT /db_xref="UniProtKB/TrEMBL:Q9X8C5" FT /protein_id="CAB40310.1" FT /translation="MAHRAPTAHAPLLDPTTLGDVLRVASAPDYTRWEDQVRRTGGCSD FT PIHLTGWTLHKDKTTGETLHHYTTAVEPGGRLRLACGNRRASRCPSCAWTYAGDTYHLV FT RAGLAGDDRRDVPATVRDHPRVFATLTAPSFGAVHNRPDHGACRCGTQHSPDAPELGTA FT LDPATYDYAGAVLFNNHAGQLWQRFTTRLRRELAARAGLTRRELADRVRVSYGKVAEFQ FT KRGALHFHAVIRLDGPDGPGTPPPAWATVGLLADAIHAAAAHSYTSVSVPAAGDQPARS FT FRWGTQLDVRPVKAFGDGSDTTEQAVVSYVAKYSTKAAENTGTLDRRIGELAELDRHQV FT PDHTRRLITACRDLDRLYPDRRLWAWAHMLGFRGHFSSKSRRYSTTLGALRQARADYRA FT TQEHTALALDDREPDTVLVLTDWQYAGHGHTPGESALAATIARDLQLNRETAREALQDQ FT LALEGAAA" FT CDS complement(257394..257711) FT /transl_table=11 FT /gene="SCO3253" FT /gene_synonym="spdD" FT /gene_synonym="SCE39.03c" FT /product="SpdD protein" FT /note="SCE39.03c, SpdD protein, len: 105aa; highly similar FT to TR:Q07196 (EMBL:AJ005260) SpdD protein from the FT integrated conjugative plasmid pSAM2 of Streptomyces FT ambofaciens (104 aa) fasta scores; opt: 491, z-score: FT 476.3, E(): 3.2e-19, (72.1% identity in 104 aa overlap). FT Contains possible membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9X8C6" FT /protein_id="CAB40311.1" FT /translation="MFRPKIPTNPTPAGHVTPPVVVESTAVVPSVQVPPPAPVAPAPSR FT PTVQLTPGTALALVGGGTAVVLVVGAVLVSLLLAVAITGASVAVCALVIRSLVQADAKR FT R" FT CDS complement(257735..257890) FT /transl_table=11 FT /gene="SCO3254" FT /gene_synonym="spdC" FT /gene_synonym="SCE39.04c" FT /product="SpdC protein" FT /note="SCE39.04c, SpdC protein, len: 51 aa; highly similar FT to TR:Q07195 (EMBL:AJ005260) SpdC protein from the FT integrated conjugative plasmid pSAM2 of Streptomyces FT ambofaciens (51 aa) fasta scores; opt: 286, z-score: 418.6, FT E(): 5.2e-16, (80.4% identity in 51 aa overlap). Largely FT hydrophobic suggesting membrane association. Contains FT possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9X8C7" FT /protein_id="CAB40312.1" FT /translation="MDVPLWLALLAVGYLGVKLIRPPWWLIAVLLLGGFLIADSVLAPV FT VNGFVK" FT CDS complement(257902..258063) FT /transl_table=11 FT /gene="SCO3255" FT /gene_synonym="spdB" FT /gene_synonym="SCE39.05c" FT /product="SpdB protein" FT /note="SCE39.05c, SpdB protein, len: 53 aa; highly similar FT to TR:Q07194 (EMBL:AJ005260) SpdB protein from the FT integrated conjugative plasmid pSAM2 of Streptomyces FT ambofaciens (58 aa) fasta scores; opt: 291, z-score: 448.0, FT E(): 1.2e-17, (83.3% identity in 48 aa overlap)." FT /db_xref="InterPro:IPR007806" FT /db_xref="UniProtKB/TrEMBL:Q9X8C8" FT /protein_id="CAB40313.1" FT /translation="MRIGPVQIGTHRDRRGQTKHAAVCTNDGCGWSADYSSQSAAQLAA FT RTHRCRVS" FT CDS complement(258126..258779) FT /transl_table=11 FT /gene="SCO3256" FT /gene_synonym="spdA" FT /gene_synonym="SCE39.06c" FT /product="SpdA protein" FT /note="SCE39.06c, SpdA protein, len: 217 aa; highly similar FT to TR:Q07193 (EMBL:AJ005260) SpdA protein form the FT integrated conjugative plasmid pSAM2 of Streptomyces FT ambofaciens (224 aa) fasta scores; opt: 1071, z-score: FT 973.6, E(): 0, (75.6% identity in 225 aa overlap). Contains FT possible membrane spanning regions and a possible FT N-terminal region signal sequence peptide" FT /db_xref="UniProtKB/TrEMBL:Q9X8C9" FT /protein_id="CAB40314.1" FT /translation="MARPALRIDAVLVQAVIAGALSFAHLHDLAAAAGQTGWKAWAYPV FT SVDLLLVAAWRRLRADGPSRLAWCWFLIALVASLGANVATAGLLDLGDVPPWLRILVAA FT WPALAFMGGTLLAHSPADPAPTPPAPSVPTQDPAPETAAAEPRPAPEPPVVSQIEETPA FT LPTAVPVPAALVDHARKVADDHHARTGTPIDTDALRARLGVPPHLADAIAAHLG" FT CDS complement(258861..260216) FT /transl_table=11 FT /gene="SCO3257" FT /gene_synonym="traSA" FT /gene_synonym="SCE39.07c" FT /product="plasmid transfer protein" FT /note="SCE39.07c, traSA, plasmid transfer protein, len: 451 FT aa; similar to many from Streptomyces spp. eg. TR:O69803 FT (EMBL:AJ005260) from the integrated conjugative plasmid FT pSAM2 of Streptomyces ambofaciens (415 aa) fasta scores; FT opt: 2515, z-score: 2911.8, E(): 0, (90.6% identity in 415 FT aa overlap) and TR:O86766 (EMBL:AL031035) TraSA integrase FT fusion protein from the Streptomyces coelicolor cosmid 6A9 FT (768 aa) fasta scores; opt: 2418, z-score: 2795.6, E(): 0, FT (89.1% identity in 405 aa overlap). Contains Prosite match FT to PS00017 ATP/GTP-binding site motif A (P-loop). Also FT contains strongly hydrophilic peak at about aa 300 and TTA FT codon, possible target for bldA regulation. FtsK/SpoIIIE FT family member." FT /db_xref="GOA:Q9X8D0" FT /db_xref="InterPro:IPR002543" FT /db_xref="UniProtKB/TrEMBL:Q9X8D0" FT /protein_id="CAB40315.1" FT /translation="MTWPTVLLLVVVAAAGFLRWRRPAWYWMTFGVTLAAVRVLVRYAS FT VMEACGLTVPPSRWRLMLARMTNRPAPESRAPRILRLRPTHTGLVLRLKLRPGQDAFDV FT AAASDRLRHSFGMYGVTSRELRSGVVEIRMTGYDVLKRVQMPAKTDTRPMRVPVALRED FT GSVHYRDYRTVPHGLTLGATESGKSVYQRNLVAGLAPHHVALVGIDCKQGVELFPLARR FT FSALADNPDTALELLEALVSHMQDVYQLIRAEQRISVAVPDAEIAADIWDLPEDLRPVP FT VVVLVDEVAELALFASKEEEKRRDRIITALVRLAQLGRAAGVYLEICGQRFGSELGKGI FT TMLRAQLTGRTAHRVNDETSANMAFGDIAPDAVLAAIQIPAETRGIAIAGDSTGGWHRI FT RAPHTTLRQAVNLCNKHADRTPELPALAPFRPAVAPLPSARVPLSKTAPATA" FT misc_feature complement(259653..259676) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature complement(260196..260198) FT /note="TTA codon. Possible target for bldA regulation." FT CDS complement(260220..260576) FT /transl_table=11 FT /gene="SCO3258" FT /gene_synonym="pra" FT /gene_synonym="SCE39.08c" FT /product="regulatory protein" FT /note="SCE39.08c, pra, regulatory protein, len: 118 aa; FT highly similar to TR:Q53733 (EMBL:AJ005260) Pra, a protein FT found to have a regulatory function in the integrated FT conjugative plasmid pSAM2 of Streptomyces ambofaciens (116 FT aa) fasta scores; opt: 655, z-score: 836.5, E(): 0, (88.1% FT identity in 118 aa overlap). Also highly similar to and FT apparently frameshifted (with high confidence in sequence) FT gene TR:O86764 and TR:O86765 (EMBL:AL031035) from FT Streptomyces coelicolor cosmid 6A9 fasta scores for FT TR:O86764; opt: 348, z-score: 456.1, E(): 4.3e-18, (88.7% FT identity in 62 aa overlap) and TR:O86765; opt: 259, FT z-score: 347.5, E(): 4.8e-12, (87.2% identity in 47 aa FT overlap)." FT /db_xref="UniProtKB/TrEMBL:Q9X8D1" FT /protein_id="CAB40316.1" FT /translation="MRQIPVDTSAATVMVAKTPQPKVRDRRTGEIATDAETGAKLMTVD FT VMFAANDEVEILSVTVPETGISGDLTMGTPAALTGLVARPWENEFNGQKRHGIAFRAVA FT VTSLATTDTGSKAA" FT CDS complement(260716..261495) FT /transl_table=11 FT /gene="SCO3259" FT /gene_synonym="korSA" FT /gene_synonym="SCE39.09c" FT /product="korSA, regulatory protein" FT /note="SCE39.09c, korSA, regulatory protein, len: 259 aa; FT highly similar to TR:Q07191 (EMBL:AJ005260) KorSA, FT regulatory protein from the integrated conjugative plasmid FT pSAM2 of Streptomyces ambofaciens (259 aa) fasta scores; FT opt: 1669, z-score: 1948.2, E(): 0, (98.5% identity in 259 FT aa overlap) and TR:O86763 (EMBL:AL031035) regulatory FT protein from Streptomyces coelicolor cosmid SC6A9 (259 aa) FT fasta scores; opt: 1655, z-score: 1931.9, E(): 0, (96.9% FT identity in 259 aa overlap). Contains Pfam match to entry FT PF00392 gntR, Bacterial regulatory proteins, gntR family." FT /db_xref="GOA:Q9X8D2" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9X8D2" FT /protein_id="CAB40317.1" FT /translation="MGTAVEGGRSGPRYVQIADEIVQQIRAGVLKPGDMVPSESELVDR FT YGVSGGTIRKAMVEVRASGLVETRHGKGSIVKDRPPVRHRSSDRFRRSLRQGGKAAYLA FT ESAQSGATAKVSVLYIGPMEAPADAAQRLGLPAGTQVLARRRLYFRNGTPVETASSYLP FT WDVVKDIPELFAENPGGGGIYARLEDHGHEFAEFVETLQARPASKAEASELALSPGAPV FT VHLIREARTTAGVVVEVCDTLMAADQFVFEYRIPAAD" FT misc_feature complement(261268..261447) FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 66.20, E-value FT 6.8e-19." FT CDS 261589..261978 FT /transl_table=11 FT /gene="SCO3260" FT /gene_synonym="SCE39.10" FT /product="MutT-like protein" FT /note="SCE39.10, MutT-like protein, len: 129aa; highly FT similar to TR:O69802 (EMBL:AJ005260) from the integrated FT conjugative plasmid pSAM2 of Streptomyces ambofaciens (131 FT aa) fasta scores; opt: 813, z-score: 1042.9, E(): 0, (94.6% FT identity in 129 aa overlap) and TR:O86762 (EMBL:AL031035) FT from Streptomyces coelicolor cosmid 6A9 (131 aa) fasta FT scores; opt: 804, z-score: 1031.5, E(): 0, (93.8% identity FT in 129 aa overlap). Contains Pfam match to entry PF00293 FT mutT, Bacterial mutT protein and Prosite match to PS00893 FT mutT domain signature." FT /db_xref="GOA:Q9X8D3" FT /db_xref="HSSP:1PUQ" FT /db_xref="InterPro:IPR020084" FT /db_xref="UniProtKB/TrEMBL:Q9X8D3" FT /protein_id="CAB40318.1" FT /translation="MREDGRLLAIRRADNGTWELPGGVLELNETPEAGVAREVWEETGI FT HVEVDELTGVYKNTTRGIVALVFRCKPSGGTERTSSESTAVSWLTPDEVSDRMAEVYAI FT RLLDALDGNGPHVRSHDGKHLIPTG" FT misc_feature 261607..261723 FT /note="Pfam match to entry PF00293 mutT, Bacterial mutT FT protein, score 58.20, E-value 3.1e-15." FT misc_feature 261655..261714 FT /note="PS00893 mutT domain signature." FT stem_loop 262215..262364 FT /note="Imperfect inverted repeat, 9/64 ( 92%) matches, with FT 22 base loop." FT misc_feature 262221..262664 FT /note="Possible region containing origin of replication for FT integrated pSAM2-like plasmid." FT misc_feature 262422..265124 FT /note="AT-rich region." FT CDS 262676..263971 FT /transl_table=11 FT /gene="SCO3261" FT /gene_synonym="SCE39.11" FT /product="putative ATP-binding protein" FT /note="SCE39.11, possible ATP-binding protein, len: 431 aa; FT limited similarity to others of unknown function eg. FT TR:Q47527 (EMBL:Z12832) hypothetical ATP-binding protein FT from Escherichia coli (492 aa) fasta scores; opt: 239, FT z-score: 271.8, E(): 7.9e-08, (32.0% identity in 153 aa FT overlap). Contains Prosite match to PS00017 ATP/GTP-binding FT site motif A (P-loop)." FT /db_xref="GOA:Q9X8D4" FT /db_xref="UniProtKB/TrEMBL:Q9X8D4" FT /protein_id="CAB40319.1" FT /translation="MVAGRNGAGKTSLLRCIALALAANPETGRALVPSYVMWRSPFDTR FT TVGKISADLFLDSGDLSDLNLEGLPEKPGTHARVGITLTPPEEIPKTGRKRSLNLGSEW FT TQVIECDDDDEEVDQAIFPTRNWFTAGYGPFRRLSSEIADPRSTRSQLVTPIDPSSVMD FT RFSTLFHEDATLGEGVSWLVGLHLRSLENEKGAGRLLQNVLEVLSDGLLPDGYSPVRVS FT SSGLWVRRQTGKAFPLKEMSDGFRTVTALVLDIIRQLHTFYGTLRMRRSKKGIAIYAPG FT VILIDEVDAHLHVGWQQRIGGWLKSHFPRIQFIVSTHSPYICQSADIGGLIRLPGLNEN FT YPPQVVGEQLYKRIVYGSGDDAALSDLFGLDTPYGSEAEKLRSKLIEIEGRVLDGSASK FT AEVRQYREMSETLTSSLSARVDEVSGRLGRRN" FT misc_feature 262685..262708 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 263968..264717 FT /transl_table=11 FT /gene="SCO3262" FT /gene_synonym="SCE39.12" FT /product="hypothetical protein" FT /note="SCE39.12, unknown, len: 249aa; limited similarity to FT others of unknown function some of which are associated FT with bacteriophage eg. SW:VE31_LAMBD protein EA31 from FT bacteriophage lambda (296 aa) fasta scores; opt: 133, FT z-score: 164.9, E(): 0.071, (35.3% identity in 85 aa FT overlap). Contains TTA codon, possible target for bldA FT regulation." FT /db_xref="InterPro:IPR003615" FT /db_xref="UniProtKB/TrEMBL:Q9X8D5" FT /protein_id="CAB40320.1" FT /translation="MIPLKRPGISANLEKRLTGKTKTLTDNLADPKNAREAWKSARTIR FT RDLKVLLASMAAGFARCMYCGDSLGTDIDHFKPIARDPLSAFIWANHFLACSHCNSNKK FT RDQYPCSPSGECLLVNPSKEDPYEHMNLNLPTGKYQGQTQKGKETIRVFGLSRPDLELG FT RAHAYVRCESMLRDWSTRVGNGQEEAASAVLKSLMIQPFADVLYAMIKKSEAPGAPNLF FT EADVLTALRSVRERIETQDVAASFRNP" FT misc_feature 264004..264006 FT /note="TTA codon. Possible target for bldA regulation." FT CDS complement(265132..265431) FT /transl_table=11 FT /gene="SCO3263" FT /gene_synonym="SCE39.13c" FT /product="conserved hypothetical protein" FT /note="SCE39.13c, unknown, len: 99 aa; similar to FT TR:CAC44711 (EMBL:AL596251) Streptomyces coelicolor FT conserved hypothetical protein SCBAC25E3.24, 101 aa; fasta FT scores: opt: 441 Z-score: 540.6 E(): 1.8e-22; 67.742% FT identity in 93 aa overlap. Contains possible coiled-coil FT region" FT /db_xref="UniProtKB/TrEMBL:Q9X8D6" FT /protein_id="CAB40321.1" FT /translation="MTAPNELRLLPWSGPEGKPCYLSTDERGGYMSRLADNVESVQLGT FT AAELLEEASETLSDRDVALDEMRRLAKELTGALQDVLRVATSRGHLLAVCEPRP" FT CDS complement(265428..266159) FT /transl_table=11 FT /gene="SCO3264" FT /gene_synonym="SCE39.14c" FT /product="putative gntR-family regulator" FT /note="SCE39.14c, possible gntR-family regulator, len: FT 243aa; weak similarity to many egs. SW:FARR_ECOLI fatty FT acyl responsive regulator from Escherichia coli (240 aa) FT fasta scores; opt: 196, z-score: 243.9, E(): 2.8e-06, FT (24.3% identity in 243 aa overlap) and SW:KORA_STRLI KorA FT protein found to control plasmid transfer in the FT Streptomyces lividans plasmid pIJ101 (241 aa) fasta scores; FT opt: 158, z-score: 198.3, E(): 0.00098, (22.0% identity in FT 227 aa overlap). Contains Pfam match to entry PF00392 gntR, FT Bacterial regulatory proteins, gntR family and Prosite FT match to PS00043 Bacterial regulatory proteins, gntR family FT signature. Also contains probable helix-turn-helix (+3.94 FT SD) 29-50aa" FT /db_xref="GOA:Q9X8D7" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9X8D7" FT /protein_id="CAB40322.1" FT /translation="MRSRHHEIADDLRHQITGGRILPSERLPSEAALADRYRVSTVTLR FT RALAVLQTEGLVEKIQGKGNFVRRPHRKIMYIGGWGTLDPWTAAEPDLRVTIRSTAVQA FT QAHLATLLEVPTGTSIVEFTCLSHEGESPHSLARVYMPHDLVPPEALDDASTSREAATR FT FAFLGPPPTAARETVSARLPAPDEASALRIGIASIVLSITRIATNSAGRVVEAALLAFP FT GDRVDAVFTTHHVIDERQSKG" FT misc_feature complement(265959..266138) FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 71.10, E-value FT 2e-20." FT misc_feature complement(266007..266081) FT /note="PS00043 Bacterial regulatory proteins, gntR family FT signature." FT CDS complement(266168..266392) FT /transl_table=11 FT /gene="SCO3265" FT /gene_synonym="SCE39.15c" FT /product="conserved hypothetical protein" FT /note="SCE39.15c, unknown, len: 74aa; similar to FT TR:CAC44709 (EMBL:AL596251) conserved hypothetical protein FT SCBAC25E3.22 from Streptomyces coelicolor (74 aa) fasta FT scores; opt: 356, Z-score: 489.1, E(): 1.3e-19, 77.465% FT identity (77.465% ungapped) in 71 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9X8D8" FT /protein_id="CAB40323.1" FT /translation="MRSYAPGGALVSNVEVTATTVQRGDIIQLGGHAFRVRDLFQLPQG FT AKQLVFESGELLTLHARTRLVAVRMLRRR" FT CDS complement(266389..266592) FT /transl_table=11 FT /gene="SCO3266" FT /gene_synonym="SCE39.16c" FT /product="hypothetical protein" FT /note="SCE39.16c, unknown, len: 67aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X8D9" FT /protein_id="CAB40324.1" FT /translation="MPRRRQPHIADPASVPYRSTACRIGTHHVCADASPTPVPADIPVI FT CEACDCPCHSGVGLSASLEVTQ" FT CDS 266634..266834 FT /transl_table=11 FT /gene="SCO3267" FT /gene_synonym="SCE39.17" FT /product="hypothetical protein" FT /note="SCE39.17, unknown, len: 66aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X8E0" FT /protein_id="CAB40325.1" FT /translation="MRGDDHRTCPDASFHRHDVRADQGHVLSSEQVSVRCRVVSCITQD FT GGRRAIGPTRDGKRRRRKGGH" FT CDS complement(266922..267200) FT /transl_table=11 FT /gene="SCO3268" FT /gene_synonym="SCE39.18c" FT /product="putative secreted protein" FT /note="SCE39.18c, putative secreted protein, len: 92 aa; FT similar to TR:CAC44706 (EMBL:AL596251) Streptomyces FT coelicolor conserved hypothetical protein SCBAC25E3.19, 92 FT aa; fasta scores: opt: 471 Z-score: 603.7 E(): 5.4e-26l; FT 81.522% identity in 92 aa overlap. Contains possible FT N-terminal region signal peptide sequence" FT /db_xref="UniProtKB/TrEMBL:Q9X8E1" FT /protein_id="CAB40326.1" FT /translation="MPASGVSAAALAARLSALGLPTRVEEHPRHTSVEAEVPDTLSAES FT WREVLDVVAEADRFGLLATSLNGRTLWAVVRKAVPSTGDVGGPSHQR" FT CDS 267280..268035 FT /transl_table=11 FT /gene="SCO3269" FT /gene_synonym="SCE39.19" FT /product="putative gntR-family regulator" FT /note="SCE39.19, possible gntR-family regulator, len: 251 FT aa; some similarity to many egs. TR:Q07191 (EMBL:AJ005260) FT KorSA protein from the integrated conjugative plasmid pSAM2 FT of Streptomyces ambofaciens (259 aa) fasta scores; opt: FT 327, z-score: 380.9, E(): 6.7e-14, (31.0% identity in 252 FT aa overlap) and TR:O86763 (EMBL:AL031035) KorSA FT transcriptional regulator from Streptomyces coelicolor FT cosmid 6A9 (259 aa) fasta scores; opt: 326, z-score: 379.7, FT E(): 7.7e-14, (28.9% identity in 249 aa overlap). Contains FT Pfam match to entry PF00392 gntR, Bacterial regulatory FT proteins, gntR family. Also contains probable FT helix-turn-helix (+4.51 SD) 31-52aa." FT /db_xref="GOA:Q9X8E2" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9X8E2" FT /protein_id="CAB40327.1" FT /translation="MPEQPPYLRIADELRRRIAEHVWEPGDRLPSRAQIGQECGVGENV FT VRRAQELLISQGVLEGRAGSGTYVAEPRQRVRVVRSSAREQPNGSPFRADMKAVGRQGD FT WESRTDAKVPAPADIAARLGIHEGDLCVRTTYEFLADGRPVQLSTSWEPYDLTGGTLVV FT LPEGGPHAGAGVVNRMAAIGITVSHAVEQPEPRQATAEEASLLGIQKAALVTHIRRTYY FT SDDGRPVETADIVVPAAHCEIVYEIPIRP" FT misc_feature 267307..267486 FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 58.40, E-value FT 1.7e-16." FT CDS 268086..268598 FT /transl_table=11 FT /gene="SCO3270" FT /gene_synonym="SCE39.20" FT /product="hypothetical protein" FT /note="SCE39.20, unknown, len: 170aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X8E3" FT /protein_id="CAB40328.1" FT /translation="MTGDLRFSWELTGSGWATYRIADATSERADIVSYCTDALSDLLRA FT VVSLYGAADAARVSFDLEPAEVRWRLQPQEANVEITIYRFRDMSQSWNVPDDEGTRCWS FT SNQPRAALGHVVLEAAETVLRLHGEAGYREKWVQHDFPGAVLDDLRRLHRRDDGCRHKS FT CQVNVHS" FT stem_loop 268752..268793 FT /note="Perfect inverted repeat, 20/20 (100%) matches, with FT 2 base loop." FT CDS 268875..269177 FT /transl_table=11 FT /gene="SCO3271" FT /gene_synonym="SCE39.21" FT /product="putative dehydrogenase" FT /note="SCE39.21, possible dehydrogenase, len: 100aa; FT similar to TR:Q53783 (EMBL:L33871) vdh, valine FT dehydrogenase from Streptomyces ambofaciens (120 aa) fasta FT scores; opt: 92, z-score: 127.5, E(): 8.6, (29.9% identity FT in 107 aa overlap)." FT /db_xref="UniProtKB/TrEMBL:Q9X8E4" FT /protein_id="CAB40329.1" FT /translation="MTQPAEPSSLGGHRGTRGSLRDPDQPLARPKVRRMADDAQLCPEC FT SQPLKSGGLVLSKRDDDGLRVCRSVWRCADRHTWWQWADRPEEVLESCPVPELFR" FT CDS complement(269412..269780) FT /transl_table=11 FT /gene="SCO3272" FT /gene_synonym="SCE39.22c" FT /product="putative DNA-binding protein" FT /note="SCE39.22c, possible DNA-binding protein, len: 122aa; FT some similarity to TR:O64356 (EMBL:AF064539) Gp48 protein FT from bacteriophage N15 (95 aa) fasta scores; opt: 114, FT z-score: 155.2, E(): 0.25, (36.6% identity in 71 aa FT overlap). Contains probable helix-turn-helix (+6.85 SD) FT 82-103aa." FT /db_xref="GOA:Q9X8E5" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q9X8E5" FT /protein_id="CAB40330.1" FT /translation="MREAAEIECAHQVQKVCEAQQGHGAHLRAAQGELMNHSTWRTRRT FT GRLEGEAVEYDQEYVDARLAGDLGQAVYDRRIELGLSRTELAERAGMTQPQVSRMEGAT FT LCRRSRCCGAWPRPWTAH" FT CDS 270013..270279 FT /transl_table=11 FT /gene="SCO3273" FT /gene_synonym="SCE39.23" FT /product="hypothetical protein" FT /note="SCE39.23, unknown, len: 88aa; contains possible FT coiled-coil." FT /db_xref="UniProtKB/TrEMBL:Q9X8E6" FT /protein_id="CAB40331.1" FT /translation="MATRKITITVPEELVESIKERVDTRGVSGYIAAAAAHQDAMDRLR FT ELAGRLEEEHGAVTDDEQQAALDRIAAIDGWHDEQGSHSGEAA" FT CDS 270276..270722 FT /transl_table=11 FT /gene="SCO3274" FT /gene_synonym="SCE39.24" FT /product="hypothetical protein" FT /note="SCE39.24, unknown, len: 148aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X8E7" FT /protein_id="CAB40332.1" FT /translation="MSRTARARLHRPRQRVFVFDSEALSKAVQGDREMTALIKTAPRLD FT IPIVTSALTTLEAWDPREAPRQSVWNWTLSRIRVVHTDDRVIAMARDMLKTAGLHGHKY FT AIDAILAAVAGQEAAQGAEATVFTSDTDDMSRLVAGHSVRVEKI" FT CDS complement(270817..271269) FT /transl_table=11 FT /gene="SCO3275" FT /gene_synonym="SCE39.25c" FT /product="putative merR-family transcriptional regulator" |