 |
|
EBI DbfetchID AL939114; SV 1; linear; genomic DNA; STD; PRO; 313800 BP. XX AC AL939114; AL096852; AL136058; AL138851-AL138852; AL163641; AL163672; AC AL353832; AL353862; AL355774; AL442165; AL499570; AL596030; AL596138; XX DT 25-OCT-2002 (Rel. 73, Created) DT 29-JUN-2009 (Rel. 101, Last updated, Version 6) XX DE Streptomyces coelicolor A3(2) complete genome; segment 11/29 XX KW . XX OS Streptomyces coelicolor OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Streptomycineae; Streptomycetaceae; Streptomyces. XX RN [1] RP 1-313800 RA Bentley S.D.; RT ; RL Submitted (09-MAY-2002) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Streptomyces sequencing team, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL sdb@sanger.ac.uk XX RN [2] RX DOI; 10.1038/417141a RX PUBMED; 12000953. RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L., RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H., RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E., RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D., RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.; RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor RT A3(2)"; RL Nature 417(6885):141-147(2002). XX RN [3] RX DOI; 10.1021/ja045774k RX PUBMED; 15600304. RA Barona-Gomez F., Wong U., Giannakopulos A.E., Derrick P.J., Challis G.L.; RT "Identification of a cluster of genes that directs desferrioxamine RT biosynthesis in Streptomyces coelicolor M145"; RL J. Am. Chem. Soc. 126(50):16282-16283(2004). XX RN [4] RX DOI; 10.1002/cbic.200400283 RX PUBMED; 15719346. RA Challis G.L.; RT "A widely distributed bacterial pathway for siderophore biosynthesis RT independent of nonribosomal peptide synthetases"; RL Chembiochem 6(4):601-611(2005). XX RN [5] RX DOI; 10.1099/mic.0.29161-0 RX PUBMED; 17074905. RA Barona-Gomez F., Lautru S., Francou F.X., Leblond P., Pernodet J.L., RA Challis G.L.; RT "Multiple biosynthetic and uptake systems mediate siderophore-dependent RT iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces RT ambofaciens ATCC 23877"; RL Microbiology (Reading, Engl.) 152(Pt 11):3355-3366(2006). XX RN [6] RX DOI; 10.1038/nchembio.2007.23 RX PUBMED; 17704771. RA Kadi N., Oves-Costales D., Barona-Gomez F., Challis G.L.; RT "A new family of ATP-dependent oligomerization-macrocyclization RT biocatalysts"; RL Nat. Chem. Biol. 3(10):652-656(2007). XX DR EMBL-CON; AL645882. DR RFAM; RF01118; PK-G12rRNA. DR SILVA-LSU; AL939114. DR SILVA-SSU; AL939114. XX FH Key Location/Qualifiers FH FT source 1..313800 FT /organism="Streptomyces coelicolor" FT /strain="A3(2)" FT /mol_type="genomic DNA" FT /db_xref="taxon:1902" FT CDS 182..1027 FT /transl_table=11 FT /gene="SCO2781" FT /gene_synonym="SCC105.12" FT /gene_synonym="desF" FT /product="hypothetical protein" FT /note="SCC105.12, hypothetical protein, len: 281 aa; FT similar to TR:CAB56689 (EMBL:AL121596) Streptomyces FT coelicolor hypothetical 28.7 kD protein, 259 aa; fasta FT scores: opt: 261 z-score: 302.6 E(): 2e-09; 34.9% identity FT in 255 aa overlap" FT /db_xref="GOA:Q9L073" FT /db_xref="InterPro:IPR007037" FT /db_xref="UniProtKB/TrEMBL:Q9L073" FT /protein_id="CAB87218.1" FT /translation="MRVPDPAPPAGSKRHPPSPALARVTFAGPDLRAFRSDGLDQSLSL FT FLPHPGQAEPAVPVELGEGWWQGWRELPEDVRAVMRSYTLRSLRRDTDGHTAEIDVDFV FT LHGLEPDSGIQAGPAARWAADAAPGDRVLLLGPAVADNRAIRFRPPEDTDLVVIWGDET FT AVPAACAIVEALPAGTRARVWLQVPHAEDVQDLRTAADAEITWLVGDAADGPEATLATL FT RAAQLPPAEHPYVWIAGESGCVKRLRRHFVGERGVDRRRVTFVGYWRRGLTEEQLREQG FT " FT RBS 1178..1183 FT CDS 1191..2633 FT /transl_table=11 FT /gene="SCO2782" FT /gene_synonym="SCC105.13" FT /gene_synonym="desA" FT /product="putative pyridoxal-dependent decarboxylase" FT /note="SCC105.13, probable pyridoxal-dependent FT decarboxylase, len: 480 aa; similar to SW:RHSB_RHIME FT (EMBL:AF110737) Rhizobium meliloti L-2,4-diaminobutyrate FT decarboxylase (EC 4.1.1.-) RhsB, 495 aa; fasta scores: opt: FT 1111 z-score: 1326.2 E(): 0; 41.9% identity in 458 aa FT overlap. Contains Pfam match to entry PF00282 FT pyridoxal_deC, Pyridoxal-dependent decarboxylase conserved FT domain" FT /db_xref="GOA:Q9L072" FT /db_xref="HSSP:1JS3" FT /db_xref="InterPro:IPR015422" FT /db_xref="UniProtKB/TrEMBL:Q9L072" FT /protein_id="CAB87219.1" FT /translation="MRSHLLNDTTAEQYRRSVTEGVERVAAKLATTDRPFTGVTVDALS FT PRIDAIDLDEPLHDTAAVLDELEDVYLRDAVYFHHPRYLAHLNCPVVIPALLGEAVLSA FT VNSSLDTWDQSAGGTLIERKLIDWTCARIGLGPAADGVFTSGGTQSNLQALLLAREEAK FT AEDFADLRIFASEASHFSVRKSAKLLGLGPDAVVSIPVDRDKRMQTVALARELERCARD FT GLVPMAVVATGGTTDFGSIDPLPEIAGLCEQYGVWMHVDAAYGCGLLASLKYRDRITGI FT ERADSVTVDYHKSFFQPVSSSAVLVRDAATLRHATYHAEYLNPRRMVQERIPNQVDKSL FT QTTRRFDALKLWMTLRVMGADGIGVLFDEVCDLAAEGWKLLAADPRFDVVVQPSLSTLV FT FRHIPADVTDPAEIDRANLYARKALFASGDAVVAGTKVAGRHYLKFTLLNPETTPADIA FT AVLDLIAGHAEQYLGDSLDRAS" FT misc_feature 1605..2399 FT /note="Pfam match to entry PF00282 pyridoxal_deC, FT Pyridoxal-dependent decarboxylase conserved domain, score FT 157.60, E-value 4.6e-45" FT CDS 2656..3897 FT /transl_table=11 FT /gene="SCO2783" FT /gene_synonym="SCC105.14" FT /gene_synonym="desB" FT /product="putative monooxygenase" FT /note="SCC105.14, probable monooxygenase, len: 413 aa; FT similar to SW:RHSE_RHIME (EMBL:AF110737) Rhizobium meliloti FT rhizobactin siderophore biosynthesis protein RhsE (EC FT 1.-.-.-), 454 aa; fasta scores: opt: 616 z-score: 727.2 FT E(): 0; 42.3% identity in 430 aa overlap and to FT SW:IUCD_ECOLI (EMBL:M18968) Escherichia coli L-lysine FT 6-monooxygenase (EC 1.13.12.10) IucD, 425 aa; fasta scores: FT opt: 802 z-score: 946.5 E(): 0; 31.6% identity in 414 aa FT overlap" FT /db_xref="GOA:Q9L071" FT /db_xref="UniProtKB/TrEMBL:Q9L071" FT /protein_id="CAB87220.1" FT /translation="MGIGLGPFNLGLACLTEPVAELNGVFLESKPDFEWHAGMFLDGAH FT LQTPFMSDLVTLADPTSPYSFLNYLKEQGRLYSFYIRENFYPLRVEYDDYCRWAARKLS FT SVRFSTTVTEVTYDEREELYAVATTSGDTYRARRLVLGTGTPPHIPDACRGLAGDFLHN FT SRYVRHRAELVKKKSITLVGSGQSAAEIYQDLLSEIDVHGYGLNWVTRSPRFFPLEYTK FT LTLEMTSPEYVDYYHALPEDTRYRLTAEQKGLFKGIDGDLINEIFDLLYQKRLGGPVPT FT RLLTNSALTSARYADGTYTLGFRQEEQGTDFEIETEGLVLATGYRYTEPEFLKPVRDRL FT RYDSRGNFDIGRNYAVDVTGGGVFLQNAGVHAHSVTSPDLGMGAYRNSCIVRELLGREY FT YPVEQSIAFQEFAV" FT RBS 3881..3885 FT CDS 3894..4448 FT /transl_table=11 FT /gene="SCO2784" FT /gene_synonym="SCC105.15" FT /gene_synonym="desC" FT /product="putative aceytltranferase" FT /note="SCC105.15, probable aceytltranferase, len: 184 aa; FT similar to SW:RHSD_RHIME (EMBL:AF110737) Rhizobium meliloti FT rhizobactin siderophore biosynthesis protein RhsD, 196 aa; FT fasta scores: opt: 257 z-score: 326.7 E(): 9.2e-11; 33.7% FT identity in 172 aa overlap and to TR:AAD46626 FT (EMBL:AF162771) Pseudomonas aeruginosa aminoglycoside FT 6'-N-acetyltransferase Aac, 193 aa; fasta scores: opt: 175 FT z-score: 226.3 E(): 3.6e-05; 28.2% identity in 174 aa FT overlap" FT /db_xref="InterPro:IPR019432" FT /db_xref="UniProtKB/TrEMBL:Q9L070" FT /protein_id="CAB87221.1" FT /translation="MSRLSTTTPVGALTLRPVDPLTDAVLLHGWLTHPKSAFWMMQDAR FT LVDVERAYMELAADEHQQAHLGLHDGVPAFLTERYDPAHRELVGLYEPEPGDVGMHFLV FT APTDRPVHGFTRAVITTVMTELFADPATRRVVVEPDVTNTAVHALNAAVGFVPEREIQK FT PEKKALLSFCTREQFAKAVSA" FT CDS 4445..6232 FT /transl_table=11 FT /gene="SCO2785" FT /gene_synonym="SCC105.16" FT /gene_synonym="desD" FT /product="conserved hypothetical protein" FT /note="SCC105.16, len: 595 aa; type C NRPS-independent FT siderophore synthetase; catalyzes ATP- and FT magnesium-dependent condensation of three molecules of FT N-hydroxy-N-succinylcadaverine to form desferrioxamine G1 FT and desferrioxamine E and two molecules of FT N-hydroxy-N-succinylcadaverine with one molecule of FT N-acetyl-N-hydroxycadaverine to form desferrioxamine B" FT /db_xref="GOA:Q9L069" FT /db_xref="InterPro:IPR007310" FT /db_xref="UniProtKB/TrEMBL:Q9L069" FT /protein_id="CAB87222.1" FT /translation="MSLADAVAHLTPERWEEANRLLVRKALAEFTHERLLTPEREPDDG FT GGQTYVVRSDDGQTAYRFTATVRALDHWQVDAASVTRHRDGAELPLAALDFFIELKQTL FT GLSDEILPVYLEEISSTLSGTCYKLTKPQLSSAELARSGDFQAVETGMTEGHPCFVANN FT GRLGFGIHEYLSYAPETASPVRLVWLAAHRSRAAFTAGVGIEYESFVRDELGAATVDRF FT HGVLRGRGLDPADYLLIPVHPWQWWNKLTVTFAAEVARGHLVCLGEGDDEYLAQQSIRT FT FFNASHPGKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLARLIEGDPVLKETGLSI FT IRERAAVGYRHLEYEQATDRYSPYRKMLAALWRESPVPSIREGETLATMASLVHQDHEG FT ASFAGALIERSGLTPTEWLRHYLRAYYVPLLHSFYAYDLVYMPHGENVILVLADGVVRR FT AVYKDIAEEIAVMDPDAVLPPEVSRIAVDVPDDKKLLSIFTDVFDCFFRFLAANLAEEG FT IVTEDAFWRTVAEVTREYQESVPELADKFERYDMFAPEFALSCLNRLQLRDNRQMVDLA FT DPSGALQLVGTLKNPLAGR" FT CDS complement(6302..7909) FT /transl_table=11 FT /gene="SCO2786" FT /gene_synonym="hexA" FT /gene_synonym="SCC105.17c" FT /product="beta-N-acetylhexosaminidase" FT /note="SCC105.17c, hexA, beta-N-acetylhexosaminidase FT precursor, len: 535 aa; highly similar to TR:O85361 FT (EMBL:AF063001) Streptomyces plicatus FT B-N-acetylhexosaminidase, Hex, 561 aa; fasta scores: opt: FT 2991 z-score: 3318.1 E(): 0; 93.2% identity in 469 aa FT overlap and to TR:BAA8876 (EMBL:AB015350) Streptomyces FT thermoviolaceus beta-N-acetylglucosaminidase precursor FT NagB, 541 aa; fasta scores: opt: 2856 z-score: 3168.6 E(): FT 0; 76.7% identity in 537 aa overlap. Contains Pfam match to FT entry PF00728 Glyco_hydro_20, Glycosyl hydrolase family 20 FT and possible N-terminal region signal peptide sequence" FT /db_xref="GOA:Q9L068" FT /db_xref="HSSP:1M03" FT /db_xref="InterPro:IPR015883" FT /db_xref="UniProtKB/TrEMBL:Q9L068" FT /protein_id="CAB87223.1" FT /translation="MRPHRRHHRTTPRITRLLGSLLLVAAVGAMTTGAAPVRKAAAEPT FT PLDRVIPAPASVEPGGAPYRITRGTHIRVDDSREARRVGDYLADLLRPATGYRLPVTSH FT GHGGIRLRLAEGPYGDEGYRLDSGREGVTITARKAAGLFHGVQTLRQLLPAAVEKDSAQ FT PGPWLVAGGTIEDTPRYAWRSAMLDVSRHFFSVDEVKRYIDRVALYKYNKLHLHISDDQ FT GWRLAIDSWPRLATYGGSTEVGGGPGGHYTKADYEEIVRYAASRHLEVVPEIDMPGHTN FT AALASYAELNCDGVAPPLYTGTKVGFSTLCVDKDVTYDFVDDVLGELAALTPGRYLHIG FT GDEAHSTPQADFVAFMKRVQPIVAKYGKTVVGWHQLAGAEPVEGALVQYWGLDRTSDAE FT KAQVAAAARNGTGLILSPADRTYLDMKYTKDTPLGLSWAGYVEVRRSYDWDPAAYLPGA FT PAEAVRGVEAPLWTETLSDPDQLDFMAFPRLPGVAELGWSPASTHDWDTYKVRLAGQAP FT HWEAMGIDYYRSPQVPWT" FT misc_feature complement(7052..7552) FT /note="Pfam match to entry PF00728 Glyco_hydro_20, Glycosyl FT hydrolase family 20, score 142.50, E-value 7.3e-39" FT RBS complement(7915..7920) FT CDS 8024..8920 FT /transl_table=11 FT /gene="SCO2787" FT /gene_synonym="SCC105.18" FT /product="conserved hypothetical protein SCC105.18" FT /note="SCC105.18, hypothetical protein, len: 298 aa; FT similar to TR:Q9RDQ8 (EMBL:AL133423) Streptomyces FT coelicolor hypothetical 31.7 kD protein SC4A7.04, 295 aa; FT fasta scores: opt: 556 z-score: 623.0 E(): 2.9e-27; 37.4% FT identity in 294 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9L067" FT /protein_id="CAB87224.1" FT /translation="MAEIIQKDGTWVFDGDALRLTPGRDKNVSLLRRELGELLVPLAAL FT AGISFEQGKKSGRLRLRLRDGADPLLHAAGGRLTEPHDPYQLLVESDRYGVAEYFVDEV FT RNALLLDQVPSGPVDAYLLPGPSVPLSVSAGDGVASFDGERVRLEWKWQAEDAKSAAGP FT RTLPLADIVAVEWQPTIGLENGHLRFTVRAAPSKVPPKYDPNAVELWGFKKDPLMALVA FT AAVQARLPHPAARAALEDARAGEDTSTPATAPPAPAAEDDHDALLRRLRELGDLHRSGV FT LTDEEFALAKQAVLKRM" FT CDS 9009..9266 FT /transl_table=11 FT /gene="SCO2788" FT /gene_synonym="SCC105.19" FT /product="hypothetical protein SCC105.19" FT /note="SCC105.19, unknown, len: 85 aa" FT /db_xref="UniProtKB/TrEMBL:Q9L066" FT /protein_id="CAB87225.1" FT /translation="MHDELVDHLTRSTPLSRGEALRVVQDVLAYFDETTEEYVRRRHRE FT LQAQGLVNATIFERIEAELKYRAVAPPELSLRQLRRIVYG" FT CDS 9336..11153 FT /transl_table=11 FT /gene="SCO2789" FT /gene_synonym="glmS2" FT /gene_synonym="SCC105.20" FT /product="glucosamine-fructose-6-phosphate FT aminotransferase" FT /note="SCC105.20, glmS2, glucosamine-fructose-6-phosphate FT aminotransferase, len: 605 aa; similar to SW:GLMS_ECOLI FT (EMBL:X01631) Escherichia coli FT glucosamine-fructose-6-phosphate aminotransferase FT [isomerizing] (EC 2.6.1.16) GlmS, 608 aa; fasta scores: FT opt: 1617 z-score: 1815.6 E(): 0; 44.1% identity in 612 aa FT overlap and highly similar to TR:BAA86263 (EMBL:AB023785) FT Streptomyces griseus ORF3 (fragment), 589 aa; fasta scores: FT opt: 3364 z-score: 3776.2 E(): 0; 87.6% identity in 589 aa FT overlap and also to SW:GLMS_STRCO (EMBL:AL031317) FT Streptomyces coelicolor GlmS1, probable FT glucosamine--fructose-6-phosphate aminotransferase FT SC6G4.18, 615 aa; fasta scores: opt: 1480 z-score: 1526.7 FT E(): 0; 43.8% identity in 621 aa overlap. Contains Pfam FT matches to entries PF00310 GATase_2, Glutamine FT amidotransferases class-II and 2x PF01380 SIS, SIS domain" FT /db_xref="GOA:Q9L065" FT /db_xref="HSSP:1MOQ" FT /db_xref="InterPro:IPR001347" FT /db_xref="UniProtKB/TrEMBL:Q9L065" FT /protein_id="CAB87226.1" FT /translation="MCGIVGYIGKRDVAPLLLEGLQRLEYRGYDSAGIVVTSPKAAGLR FT MVKAKGRVRDLEAKVPARFKGTTGIAHTRWATHGAPSDVNAHPHMSADNKVAVVHNGII FT DNAADLRRKLEADGVEFLSETDTEVLVHLIARSEAEKLEDKVRETLRVIEGTYGIAVMH FT ADFPERIVVARNGSPVVLGIGEKEMFVASDIAALVAHTRQIVTLDDGEMATLKADDFRT FT YTTEGTRTTSEPTTVEWEAASYDMGGHDTYMHKEIHEQAEAVDRVLRGRIDDRFSTVHL FT GGLNLDARDARAVRRVKILGCGTSYHAGQIGAQMIEELARIPADAEPASEFRYRNAVVD FT PDTLYIAVSQSGETYDVLAAVQELKRKGARVLGIVNVVGSAIAREADGGMYVHAGPEVC FT VVSTKCFTNTCVAFALLALHLGRTRDLSVRDGKRIIEGLRKLPAQIEEMLKQEEDVKKL FT AAQYAEARSMLFIGRVRGYPVAREASLKLKEVSYIHAEAYPASELKHGPLALIEPALPT FT VAIVPDDDLLEKNRAALEEIKARSGQILAVAHQEQEKADHTIVVPKNEDELDPILMGIP FT LQLLAYHTALALGRDIDKPRNLAKSVTVE" FT misc_feature 9339..9881 FT /note="Pfam match to entry PF00310 GATase_2, Glutamine FT amidotransferases class-II, score 264.50, E-value 1.3e-89" FT misc_feature 10197..10601 FT /note="Pfam match to entry PF01380 SIS, SIS domain, score FT 147.70, E-value 2e-40" FT misc_feature 10710..11108 FT /note="Pfam match to entry PF01380 SIS, SIS domain, score FT 88.50, E-value 1.3e-22" FT CDS complement(11169..11696) FT /transl_table=11 FT /gene="SCO2790" FT /gene_synonym="SCC105.21c" FT /product="conserved hypothetical protein SCC105.21c" FT /note="SCC105.21c, hypothetical protein, len: 175 aa; FT highly similar to TR:BAA86264 (EMBL:AB023785) Streptomyces FT griseus ORF2, 173 aa; fasta scores: opt: 998 z-score: FT 1157.6 E(): 0; 82.9% identity in 175 aa overlap" FT /db_xref="GOA:Q9L064" FT /db_xref="InterPro:IPR006016" FT /db_xref="UniProtKB/TrEMBL:Q9L064" FT /protein_id="CAB87227.1" FT /translation="MAGHEFFEPADRKRPVAEPTAAEPLAAEEPRQSCDPAFKHGVVVG FT FDGSTSSERALAYAIGMASRLGSGLVIVHVANRLPTTVWAGCEPPVFVDVPDHRTEVLG FT LELACADYLAEVSWILVERGGDICHELEEVGREYEADAIVVGSSHGLVGRLFGSVAGRL FT AKRAKRPVVVIP" FT CDS complement(12002..12313) FT /transl_table=11 FT /gene="SCO2791" FT /gene_synonym="SCC105.22c" FT /product="hypothetical protein SCC105.22c" FT /note="SCC105.22c, unknown, len: 103 aa" FT /db_xref="UniProtKB/TrEMBL:Q9L063" FT /protein_id="CAB87228.1" FT /translation="MRGNRSVDRCFFPSVPPAPACLPPTSARPLPGRDPLGTPQQQTAR FT GGDGGQAEGRAGGAREGGAVPEERHRDEEAAERRPADEIGDAVPVGCAGRRVGGTVRS" FT CDS 12685..13881 FT /transl_table=11 FT /gene="SCO2792" FT /gene_synonym="adpA" FT /gene_synonym="SCC105.23" FT /product="araC-family transcriptional regulator" FT /note="SCC105.23, adpA, araC-family transcriptional FT regulator, len: 398 aa; highly similar to TR:BAA86265 FT (EMBL:AB023785) Streptomyces griseus AdpA, 405 aa; fasta FT scores: opt: 2219 z-score: 2270.5 E(): 0; 84.4% identity in FT 410 aa overlap and to TR:Q9XA73 (EMBL:AL096822) FT Streptomyces coelicolor putative araC-family FT transcriptional regulator SCGD3.05, 334 aa; fasta scores: FT opt: 878 z-score: 904.2 E(): 0; 45.7% identity in 313 aa FT overlap. Contains Pfam match to entry PF00165 HTH_AraC, FT Bacterial regulatory helix-turn-helix proteins, araC family FT and match to Prosite entry PS00041 Bacterial regulatory FT proteins, araC family signature. Contains possible FT helix-turn-helix motif" FT /db_xref="GOA:Q9L062" FT /db_xref="InterPro:IPR002818" FT /db_xref="UniProtKB/TrEMBL:Q9L062" FT /protein_id="CAB87229.1" FT /translation="MSHDSTAAPEAAARKLSGRRRKEIVAVLLFSGGPIFESSIPLSVF FT GIDRQDAGVPRYRLLVCAGEDGPLRTTGGLELTAPQGLEAISRAGTVVVPAWRSITSPP FT PEEALDALRRAHEEGARIVGLCTGAFVLAAAGLLDGRPATTHWMYAPTLAKRYPSVHVD FT PRELFVDDGDVLTSAGTAAGIDLCLHIVRTDHGNEAAGALARRLVVPPRRSGGQERYLD FT RSLPEEIGADPLAEVVAWALEHLHEQFDVETLAARAYMSRRTFDRRFRSLTGSAPLQWL FT ITQRVLQAQRLLETSDYSVDEVAGRCGFRSPVALRGHFRRQLGSSPAAYRAAYRARRPQ FT GDRQPDPDTAAAGATRPLPPSDPPASLAPENAVPFQTRRTATPMPAGAASVPGQRSAP" FT misc_feature 13357..13359 FT /gene="none" FT /note="TTA Leucine codon. Possible target for bldA FT regulation" FT misc_feature 13426..13686 FT /note="Pfam match to entry PF00165 HTH_AraC, Bacterial FT regulatory helix-turn-helix proteins, araC family, score FT 75.80, E-value 8.8e-19" FT misc_feature 13537..13665 FT /note="PS00041 Bacterial regulatory proteins, araC family FT signature" FT stem_loop 13902..13982 FT /note="26633 GAACGCCGGACGGGCCGGAGCGTG-CCCGTCCGGC FT 26666-26680 GCCGGGCGGGGCACACTCAG-CCCGTCCGGCGTTC 26713. FT Score 54: 30/33 (90%) matches, 2 gaps" FT misc_feature 14113..15970 FT /note="previously sequenced DNA fragment. EMBL:AB036424 FT Streptomyces coelicolor A3(2) adpA, ornA, orf5-h genes for FT AdpA homolog, oligoribonuclease, transcriptional regulator, FT partial and complete cds." FT CDS 14223..14825 FT /transl_table=11 FT /gene="SCO2793" FT /gene_synonym="ornA" FT /gene_synonym="2SCC13.01" FT /product="oligoribonuclease" FT /note="2SCC13.01, ornA, oligoribonuclease, len: 200 aa; FT identical to previously sequenced TR:BAB03461 FT (EMBL:AB036424) Streptomyces coelicolor oligoribonuclease FT OrnA, 200 aa. Contains Pfam match to entry PF00929 FT Exonuclease, Exonuclease" FT /db_xref="GOA:P57666" FT /db_xref="HSSP:1J9A" FT /db_xref="InterPro:IPR006055" FT /db_xref="UniProtKB/Swiss-Prot:P57666" FT /protein_id="CAC10102.1" FT /translation="MNDRMVWIDCEMTGLSLSDDALIEVAALVTDSELNILGEGVDIVI FT RPPERALETMPEVVREMHTASGLLAELDGGTTLADAEAQVLAYVREHVKEPGKAPLCGN FT SVGTDRGFLLRDMATLEGYLHYRIVDVSSIKELARRWYPRAYFNSPEKNGNHRALADIR FT ESIAELRYYREAVFVPQPGPDSDTARAIAAKHVVSAG" FT misc_feature 14235..14753 FT /note="Pfam match to entry PF00929 Exonuclease, FT Exonuclease, score 76.80, E-value 4.6e-19" FT tRNA 14947..15019 FT /note="tRNA His anticodon GTG, Cove score 71.04" FT stem_loop 15026..15063 FT /note="possible stem loop. Score 57: 18/18 (100%) matches, FT 0 gaps" FT CDS complement(15387..16442) FT /transl_table=11 FT /gene="SCO2794" FT /gene_synonym="2SCC13.02c" FT /product="lacI-family transcriptional regulatory protein" FT /note="2SCC13.02c, lacI-family transcriptional regulatory FT protein, len: 351 aa; highly similar to TR:Q9X9R3 FT (EMBL:AJ009798) Streptomyces reticuli CebR protein, 350 aa; FT fasta scores: opt: 2011 z-score: 2174.4 E(): 0; 89.4% FT identity in 350 aa overlap and C-terminal region identical FT to TR:BAB03462 (EMBL:AB036424) Streptomyces coelicolor FT transcriptional regulator (fragment) ORF5-H, 193 aa. FT Contains Pfam matches to entries PF00356 lacI, Bacterial FT regulatory proteins, lacI family and PF00532 FT Peripla_BP_like, Periplasmic binding proteins and sugar FT binding domain of the LacI family and match to Prosite FT entry PS00356 Bacterial regulatory proteins, lacI family FT signature. Also contains a possible helix-turn-helix motif FT at residues 14..35 (+6.05 SD)" FT /db_xref="GOA:Q9F3I7" FT /db_xref="HSSP:1LCC" FT /db_xref="InterPro:IPR001761" FT /db_xref="UniProtKB/TrEMBL:Q9F3I7" FT /protein_id="CAC10103.1" FT /translation="MASHGVRGRSGGRPTLEEVAARAGVGRGTVSRVINGSPRVSDATR FT AAVEAAVAELGYVPNTAARALAANRTDAIALVVPEPETRFFAEPYFSDMLKGVGSELSE FT TEMQLLLIFAGSDRERERLAQYLAAHRVDGVLLVSVHADDPLPDLLTQLEIPAVISGPR FT SAAEPLASVDSDNYGGARSAVEHLLSRGRGRVAHITGHLAVYGAQRRVDGYRDALREAG FT HEVDEGLIEPGDFTEEGGRRAMAELLRRHPDVDAVFAASDVTAAGAGQVLREAGRRIPD FT DVALVGYDDSAIARHMEPPLTSVRQPIEEMGRAMIDLLLTEIADRRPAASRGLERHQVV FT LATELVERRSS" FT misc_feature complement(15498..16235) FT /note="Pfam match to entry PF00532 Peripla_BP_like, FT Periplasmic binding proteins and sugar binding domain of FT the LacI family., score 159.90, E-value 4.3e-44" FT misc_feature complement(16326..16409) FT /note="Pfam match to entry PF00356 lacI, Bacterial FT regulatory proteins, lacI family, score 35.50, E-value FT 1.5e-08" FT misc_feature complement(16341..16397) FT /note="PS00356 Bacterial regulatory proteins, lacI family FT signature" FT RBS complement(16446..16449) FT RBS 16797..16802 FT CDS 16808..18133 FT /transl_table=11 FT /gene="SCO2795" FT /gene_synonym="2SCC13.03" FT /product="putative sugar binding secreted protein" FT /note="2SCC13.03, probable sugar binding secreted protein, FT len: 441 aa; highly similar to TR:Q9X9R7 (EMBL:AJ009797) FT Streptomyces reticuli Cbp protein precursor (fragment) FT CebE, 444 aa; fasta scores: opt: 1490 z-score: 1672.5 E(): FT 0; 51.2% identity in 445 aa overlap and similar to FT SW:LACE_AGRRD (EMBL:X66596) Agrobacterium radiobacter FT Lactose-binding protein precursor LacE, 422 aa; fasta FT scores: opt: 263 z-score: 298.4 E(): 4.1e-09; 23.1% FT identity in 398 aa overlap. Contains Pfam match to entry FT PF01547 SBP_bacterial_1, Bacterial extracellular FT solute-binding protein and correctly situated match to FT Prosite entry PS00013 Prokaryotic membrane lipoprotein FT lipid attachment site. Also contains possible N-terminal FT region signal peptide sequence" FT /db_xref="GOA:Q9F3I6" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:Q9F3I6" FT /protein_id="CAC10104.1" FT /translation="MRAARRGSARRVVVMAAIASLGAGLLAGCADDGNDEDSSSSGDSS FT GKTTITLGLFGTMGFKEAGLYDEYEKLNPDINIEENVTERNENYYPALVNHLTTNSGLQ FT DVQAIEVGNIAEVVATQADKFEDMSKAAGVQKANWLDWKWQQATTKDGATIGLGTDIGP FT MAICYRKDLFEKAGLPTDREEVSKLWAGDWNKFIEAGEKYKKGAGKDTYFMDSPGGLIN FT AILSSEDEKFYDASGKVIYKTNPAVKDAFDLTAEAAEKGLVQSQTQFQPAWDQTISNSL FT FATVACPPWMLGTIKAKSQPDSAGKWDVAQAPKAGNWGGTFLGVPKSGKHVKEAQKLVT FT WLTAPEQQAKLFSKMGSFPSAPAAYKLPQVTGGKNDMTGDAPIGELFAKAAEQIPTQVI FT GPKDQIVQQGLTDNGVILVTQGKSAEDAWDNAVKTIDNNLEK" FT misc_feature 16862..16894 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature 17258..18118 FT /note="Pfam match to entry PF01547 SBP_bacterial_1, FT Bacterial extracellular solute-binding protein, score FT 35.20, E-value 7.1e-09" FT RBS 18124..18127 FT CDS 18139..19152 FT /transl_table=11 FT /gene="SCO2796" FT /gene_synonym="2SCC13.04" FT /product="putative cellobiose transport permease" FT /note="2SCC13.04, probable cellobiose transport permease, FT len: 337 aa; highly similar to TR:Q9X9R6 (EMBL:AJ009797) FT Streptomyces reticuli permease CebF protein, 305 aa; fasta FT scores: opt: 1416 z-score: 1722.4 E(): 0; 67.9% identity in FT 296 aa overlap. Contains Pfam match to entry PF00528 FT BPD_transp, Binding-protein-dependent transport systems FT inner membrane component and match to Prosite entry PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign. Also contains possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q9F3I5" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9F3I5" FT /protein_id="CAC10105.1" FT /translation="MTTRHDTAASPVKGGAAPGRPPGGRASAEADRRKRAKLSRRWQRD FT MRWSPYAFVSPFFLLFLAFGLFPLIYTGWASLHTVELTAPTDMQWTGLDNYTRIFDDEF FT FWNAAKNTLWIGVISTVPQLLMAMGLAHILNYKLRASTFYRVVMLAPYATSIAAASLVF FT VLLFGRDYGMINWVLDLVGLDKIDWQNGSWSSKFAVSTIVIWRWTGYNALIYLAAMQAI FT PQDLYESAALDGASRWRQFIHVTLPSLRPTILFTVVVSTIGASQVFGEPLLFDANKGAS FT GGSQHQFQTLGLYLYEQGWVNQHLGRASAIAWAMFLILIVIGVLNAVISRRLRASS" FT misc_feature 18790..19032 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 54.20, E-value 2.8e-12" FT misc_feature 18793..18879 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT RBS 19151..19156 FT CDS 19165..20076 FT /transl_table=11 FT /gene="SCO2797" FT /gene_synonym="2SCC13.05" FT /product="putative cellobiose transport permease" FT /note="2SCC13.05, probable cellobiose transport permease, FT len: 303 aa; highly similar to TR:Q9X9R5 (EMBL:AJ009797) FT Streptomyces reticuli permease CebG protein, 275 aa; fasta FT scores: opt: 1262 z-score: 1477.0 E(): 0; 67.8% identity in FT 276 aa overlap. Contains Pfam match to entry PF00528 FT BPD_transp, Binding-protein-dependent transport systems FT inner membrane component and match to Prosite entry PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign. Also contains possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q9F3I4" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9F3I4" FT /protein_id="CAC10106.1" FT /translation="MTTTMTKPPADAAPEPPRRGRRRSKASRAGGTLHAGPVAYIILAL FT FTIGSLFPLVWTAIAASRDNQRLAQTPPPLWFGGNLFDKLEIAWNDANLGEAFLNTTIV FT AGISACTIVFLSTVAGFAFAKLRFRGRNALMLIVVGTMMVPPQLSIIPLYMMVAKLDWS FT DQLQAVILPSLVNAFGVFFMRQYLLQALPDEIIEAARVDGASSWRVMWHVVFPAARPAM FT AVLGMLMFVQSWNDFLWPFLVLTQNGSPTVQVALAGLGRGYTPDQSLIMAGALLGTLPL FT LLVFAIFGKQIVGGIMQGAVKG" FT misc_feature 19723..19947 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 65.80, E-value 8.9e-16" FT misc_feature 19726..19812 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT RBS 20209..20212 FT CDS 20220..21659 FT /transl_table=11 FT /gene="SCO2798" FT /gene_synonym="2SCC13.06" FT /product="putative cellobiose hydrolase" FT /note="2SCC13.06, probable cellobiose hydrolase, len: 479 FT aa; highly similar to TR:Q59976 (EMBL:Z29625) Streptomyces FT sp. beta-glucosidase (EC 3.2.1.21) (cellobiose) Bgl3, 479 FT aa; fasta scores: opt: 2214 z-score: 2511.6 E(): 0; 65.5% FT identity in 472 aa overlap. Contains Pfam match to entry FT PF00232 Glyco_hydro_1, Glycosyl hydrolase family 1 and FT matches to Prosite entries PS00653 Glycosyl hydrolases FT family 1 N-terminal signature and PS00572 Glycosyl FT hydrolases family 1 active site" FT /db_xref="GOA:Q9F3I3" FT /db_xref="HSSP:1GON" FT /db_xref="InterPro:IPR001360" FT /db_xref="UniProtKB/TrEMBL:Q9F3I3" FT /protein_id="CAC10107.1" FT /translation="MLESATPVTPVTFPPAFLWGAATSAYQIEGAVREDGRTPSIWDTF FT SHTPGKTAGGDTGDVAVDHYHRYRDDVALMKDLGLGAYRFSISWPRVQPTGRGPAVQRG FT LDFYRRLVDELLAAGIKPAVTLYHWDLPQELEDAGGWPERDTAYRFAEYAQIVGEALGD FT RVEQWITLNEPWCAAFLGYASGVHAPGRTDPAAALRAAHHLNLAHGLGTVALRSVMPAR FT NSVAISLNTSVVRPLSQSPADLAAARKIDDLSGGIFHGPILHGAYPQTLLEATAPLTDW FT SFVQDGDLGQIRQPIDAICLNYYTPTVVSAADADSRAPRADGHGASDHSPWPAAEDVAF FT HQPPGERTEMGWTVDPTGLHELIMRYNREAPGMPLYISENGAAYDDKPGADGTVHDPDR FT VAYLNGHLTAVRQAIADGADVRGYYLWSLLDNFEWAYGYEKRFGAVYVDYASQQRTPKS FT SALWYGRAARTGTLPPVDAAE" FT misc_feature 20244..21647 FT /note="Pfam match to entry PF00232 Glyco_hydro_1, Glycosyl FT hydrolase family 1, score 690.50, E-value 8.4e-204" FT misc_feature 20268..20312 FT /note="PS00653 Glycosyl hydrolases family 1 N-terminal FT signature" FT misc_feature 21342..21368 FT /note="PS00572 Glycosyl hydrolases family 1 active site" FT CDS complement(21734..23203) FT /transl_table=11 FT /gene="SCO2799" FT /gene_synonym="2SCC13.07c" FT /product="putative secreted sugar hydrolase" FT /note="2SCC13.07c, possible secreted sugar hydrolase, len: FT 489 aa; similar to the C-terminal region of TR:Q9UWR7 FT (EMBL:AB024740) Pyrococcus kodakaraensis chitinase PK-ChiA, FT 1215 aa; fasta scores: opt: 671 z-score: 561.2 E(): FT 9.4e-24; 31.6% identity in 471 aa overlap. Contains Pfam FT match to entry PF00553 CBD_2, Cellulose binding domain and FT 3x degenerate repeat: PAPT(P/G)TP. Also possible N-terminal FT region signal peptide sequence" FT /db_xref="GOA:Q9F3I2" FT /db_xref="HSSP:1E5C" FT /db_xref="InterPro:IPR012291" FT /db_xref="UniProtKB/TrEMBL:Q9F3I2" FT /protein_id="CAC10108.1" FT /translation="MRTHRRKVSGRNKAIGALVAAAVAGGGALLFTSTAQAASVGAAYT FT KTSEWSTGYTAQYVVTNNSGQTKADWTLEFDLPSGAKLGSLWNAESKADGQHVTVTPPK FT WDTDGLKAGESVTVGFVVNGTADPTGCLVDAAACSTDDGATPEPGGRPTDPPAPTPTPT FT PTATDSTEPAPTGTPTPPAPTGTPGDGTAAGAGFAPYVDTSLYPAFDLLAHSAATGVKE FT YNLAFVTDGGGCTPKWGGVTDLGSDAVANQIGALRAEGGDVRVSFGGASGSELGTTCTS FT ADALAAAYGKVVDAYKLTKVDFDVEGGALPDTAANTRRAQAIAALQKQHPGLDVSFTLP FT VMPEGLTQAGVDLLADAKENGVGIDAVNIMAMDYGPAYSGDMGTYAEQAATATQAQIKG FT VLGRSDADAWKTVAVTPMIGVNDVASEVFKVEDATQLVKFAKSKGLGALSMWSATRDKA FT CAGGPKPSADATCSSVDQEPSAFAKALAAYK" FT repeat_region complement(22643..22738) FT /note="3x degenerate repeat translated in 2SCC13.07c" FT misc_feature complement(22790..23086) FT /note="Pfam match to entry PF00553 CBD_2, Cellulose binding FT domain, score 63.90, E-value 2.8e-17" FT misc_feature 23363..23368 FT /note="AseI site matched ATTAAT. Divides AseI-C and AseI-E FT genomic restriction fragments" FT /note="Cleavage site for AseI restriction endonuclease FT AT*TAAT." FT misc_feature complement(23363..23368) FT /note="Cleavage site for AseI restriction endonuclease FT AT*TAAT." FT CDS complement(23364..24776) FT /transl_table=11 FT /gene="SCO2800" FT /gene_synonym="2SCC13.08c" FT /product="putative two component system histidine kinase" FT /note="2SCC13.08c, probable two component system histidine FT kinase, len: 470 aa; similar to many other Streptomyces FT coelicolor two component system histidine kinases, e.g. FT TR:Q9RK59 (EMBL:AL132662) putative histidine kinase protein FT SCF11.31c, 442 aa; fasta scores: opt: 1185 z-score: 1227.7 FT E(): 0; 47.1% identity in 448 aa overlap. Contains Pfam FT matches to entries PF00672 DUF5, HAMP domain and PF00512 FT signal, Histidine kinase. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q9F3I1" FT /db_xref="HSSP:1JOY" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9F3I1" FT /protein_id="CAC10109.1" FT /translation="MRWALVKVSLAVTAMVVVAFAVPLGLVIREMARDRAFSNAEREAA FT AVAPALSITTDREQLERVVASAGSDAGMAVHIPAPGDRSGGATDIGRQRATDEDIAAVR FT RMGRASTTEVGGGSTLLQPVALSSGEIAVVEVYVPESEVTNGVGTAWAVLAAVGAALIV FT GSVAVADRLGVRMVQPARRLVEGAHELGEGRLGARVPVEGPDELRRAAVAFNSMADQVV FT QLLANERELAADLSHRLRTPLTVLRLNAASLGDGPAAEQTRAAVEQLEREVDTIIRTAR FT DAKPQTAVAGPGAGCDAAEVVRERMGFWSALAEDEGRKWRVAGADRPVRIPVARTDLAA FT SLDALLGNVFRHTAEGTAFAVDLHNGEDAVIVLVSDAGTGIADPEAAMARGRGSGTDGS FT TGLGLDIVRRMAESTGGDVRIGASVLGGTEVRIWIQLDGRTAPARRGHRGAVRRRRQSR FT APAPAAPAGRDH" FT misc_feature complement(23472..24068) FT /note="Pfam match to entry PF00512 signal, Histidine FT kinase, score 10.50, E-value 1.1e-05" FT misc_feature complement(24108..24317) FT /note="Pfam match to entry PF00672 DUF5, HAMP domain, score FT 57.70, E-value 2.4e-13" FT CDS complement(24773..25486) FT /transl_table=11 FT /gene="SCO2801" FT /gene_synonym="2SCC13.09c" FT /product="putative two component system response regulator" FT /note="2SCC13.09c, probable two component system response FT regulator, len: 234 aa; similar to many other Streptomyces FT coelicolor two component system response regulators, e.g. FT TR:Q9RK58 (EMBL:AL132662) putative response regulator FT SCF11.32c, 238 aa; fasta scores: opt: 894 z-score: 1031.1 FT E(): 0; 60.6% identity in 226 aa overlap. Contains Pfam FT matches to entries PF00072 response_reg, Response regulator FT receiver domain and PF00486 trans_reg_C, Transcriptional FT regulatory protein, C terminal" FT /db_xref="GOA:Q9F3I0" FT /db_xref="HSSP:1KGS" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9F3I0" FT /protein_id="CAC10110.1" FT /translation="MPPMASVLVVEDDQFVRSALIRQLTDASHTVRSVGTALEALREVA FT HFRFDVVILDLGLPDLDGSEALKMLRGITDVPVIVATARDDEAEVVRLLNAGADDYLTK FT PFSVEHLSARMAAVLRRARGGPAEAAPPTVLRVGGLTVDPLRRQAELDGTALDLTRREF FT DLLAFLAGRPGVVVPRKELLAEVWQQSYGDDQTIDVHLSWLRRKLGETAARPRYLHTLR FT GVGVKLEPPRLEPPR" FT RBS complement(24785..24788) FT misc_feature complement(24812..25027) FT /note="Pfam match to entry PF00486 trans_reg_C, FT Transcriptional regulatory protein, C terminal, score FT 88.30, E-value 4.4e-25" FT misc_feature complement(25142..25474) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 124.90, E-value 1.5e-33" FT RBS 25580..25583 FT CDS 25588..26169 FT /transl_table=11 FT /gene="SCO2802" FT /gene_synonym="2SCC13.10" FT /product="putative secreted protein" FT /note="2SCC13.10, possible secreted protein, len: 193 aa. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="UniProtKB/TrEMBL:Q9F3H9" FT /protein_id="CAC10111.1" FT /translation="MAAMRRGLVHVIAWLLATGAAVTLSWWGVHTVMAGTAYDAPRALP FT ITAADASVRGGEGDGGESLASSTSRPSPAPSASPSSGSASPTPSGTSREPGPAPARTTP FT STAPPEDPVSPAPDTSGDVKSYDTDGGRAVFDLGTSSASLVSATPGTGWSMQVWKTESW FT IRVEFTSGADRVSVFCTWHDGPPRVEIGSY" FT misc_feature 25780..25938 FT /note="high content region in proline, serine and alanine FT amino acids residues. Also high content in G+C (84.27%)" FT CDS complement(26198..27067) FT /transl_table=11 FT /gene="SCO2803" FT /gene_synonym="2SCC13.11c" FT /product="hypothetical protein" FT /note="2SCC13.11c, hypothetical protein, len: 289 aa; FT similar to TR:CAB95777 (EMBL:AL359949) Streptomyces FT coelicolor hypothetical 29.6 kDa protein 2SCG61.02c, 281 FT aa; fasta scores: opt: 1064 z-score: 1175.8 E(): 0; 61.4% FT identity in 267 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9F3H8" FT /protein_id="CAC10112.1" FT /translation="MGKSRNARRGRAAAEAVVEDVDGGRAELVPDRDRPRAWTLLIDGA FT PQSHVDLDDPAYLSFEYQRRIGHVIDLTAPPGRPLRAVHLGGGALTLARYVAATRPRST FT QQVVERDAALVQLVRRELPLDPGARIRVRSTDARAGLAKVPDGWADLVVADVFGGARTP FT AHLTSTEFLDEVRRALAPGGVYAANLADGPPLAHLRGQIATAAARFAALALVADPAVLR FT GRRFGNAILVAADHPLPVAELTRRAASDPHPARVEHGRALTDFAGGAHPVTDAAAVDSP FT APPESVFK" FT CDS complement(27116..27511) FT /transl_table=11 FT /gene="SCO2804" FT /gene_synonym="2SCC13.12c" FT /product="hypothetical protein" FT /note="2SCC13.12c, hypothetical protein, len: 131 aa; FT similar to TR:O86827 (EMBL:AL031225) Streptomyces FT coelicolor hypothetical 15.7 kDa protein SC8B7.06c, 152 aa; FT fasta scores: opt: 232 z-score: 266.8 E(): 2.4e-07; 41.6% FT identity in 113 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9F3H7" FT /protein_id="CAC10113.1" FT /translation="MVEAGMDTSVSVPPCDACDVVTVPTRQGLEAVDILRRGAGDGVGP FT VLHDGGCDTLGFLVPPGTAAAWDVPGSTCTETDGRGLSIVPAPEPPVEGSAWLLPPGEA FT DLATDPAVLRAALGEAARLIRAADSCR" FT RBS complement(27518..27523) FT RBS 27768..27771 FT CDS 27780..29219 FT /transl_table=11 FT /gene="SCO2805" FT /gene_synonym="2SCC13.13" FT /product="conserved hypothetical protein" FT /note="2SCC13.13, hypothetical protein, len: 479 aa; FT similar to SW:SP15_STRGR (EMBL:M32687) Streptomyces griseus FT sporulation related protein ORF1590, 529 aa; fasta scores: FT opt: 413 z-score: 469.3 E(): 1.2e-18; 30.4% identity in 326 FT aa overlap. Contains 2x conserved repeat: YETHD and 3x FT degenerate repeat: D(T/A)QD(V/L)" FT /db_xref="UniProtKB/TrEMBL:Q9F3H6" FT /protein_id="CAC10114.1" FT /translation="MASSTVTSAQPERPPRPNLAFRRLRGKRSPAEFAAAVRRAAREIG FT ERVSCDARYVGRVEAGEIRCPNYAYERVFLHMFPGRTLTDLGFAPRSSVRGRQARTPGE FT SRGAGEPYETHDTQDVLDTQDVRDAQDLYETHDNNEESDVLRRAFMTSGATVAAASLGP FT LGLAVDAAAAGRPARRAGTGEAGALEEAVRRIRLLDDRHGADGLYRRAAAPLRTAYALL FT DAGVSRQATADRIYTGAGELAISVGWLAHDSGRFDDARSHYAEALATARMNGDAGLEAH FT AFCNMAFLARDAGRPREAVRAAQAAQRAARPLGSARLMSLLALREAGGWAGLADRVGCE FT QALVRAQTFFERGPSDTDPEWMSFYGEAELEGLEAQCWSTLGDWPRAARHARRAADLQD FT PHFTRNLALYSAELADDLARGGRPDEAAGAGMRVLDLLGEVQSSRIHTMLAGTARVLLP FT HRRASGVSTFLDRHAALPRPA" FT repeat_region 28113..28127 FT /note="2x conserved repeat translated in 2SCC13.13" FT repeat_region 28125..28175 FT /note="3x degenerate repeat translated in 2SCC13.13" FT repeat_region 28176..28190 FT /note="2x conserved repeat translated in 2SCC13.13" FT misc_feature 28638..28727 FT /note="region with high content in alanine amino acid FT residues" FT CDS complement(29518..30114) FT /transl_table=11 FT /gene="SCO2806" FT /gene_synonym="2SCC13.14c" FT /product="putative mutase" FT /note="2SCC13.14c, possible mutase, len: 198 aa; similar to FT TR:O05852 (EMBL:Z95120) Mycobacterium tuberculosis FT hypothetical 21.9 kDa protein MTCY07D11.12c, 203 aa; fasta FT scores: opt: 487 z-score: 602.4 E(): 4.7e-26; 42.3% FT identity in 194 aa overlap. Contains Pfam match to entry FT PF00300 PGAM, Phosphoglycerate mutase family" FT /db_xref="HSSP:1FZT" FT /db_xref="InterPro:IPR013078" FT /db_xref="UniProtKB/TrEMBL:Q9F3H5" FT /protein_id="CAC10115.1" FT /translation="MAPRILLARHGQTEWSLSGRHTGRTDVPLLEEGRRGAKLLGERLH FT RAPWDGLDGVEVRTSPLVRASETCELAGFGERARAWDTLMEWDYGAYEGMTPEQIQAVR FT PGWLIWRDGAPEGEGVADVTARADEVVAWAREAERDVLVFAHGHVLRAIGARWLGLPVS FT FGARIRLSPTSLSVLGWAYGEPAVESWNDLGHLVG" FT misc_feature complement(29632..30099) FT /note="Pfam match to entry PF00300 PGAM, Phosphoglycerate FT mutase family, score 79.10, E-value 9.1e-21" FT RBS 30316..30320 FT CDS 30330..31319 FT /transl_table=11 FT /gene="SCO2807" FT /gene_synonym="2SCC13.15" FT /product="putative integral membrane protein" FT /note="2SCC13.15, possible integral membrane protein, len: FT 329 aa; similar to TR:CAB90881 (EMBL:AL355752) Streptomyces FT coelicolor putative integral membrane protein SC10B7.28, FT 287 aa; fasta scores: opt: 598 z-score: 630.9 E(): 1.2e-27; FT 37.7% identity in 284 aa overlap. Contains possible FT hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9F3H4" FT /protein_id="CAC10116.1" FT /translation="MPHTETPGTEAAPHPRLRWWTELPLIVLVYACYSAGRLLVRGDVS FT DAVDHGLAILDIEKALHLNAEHPLNRLFTREPWIGVPADFWYASLHYVVTPAILIWLFR FT SRAVRYRAARTWLMTSTFIGLIGFTLLPTCPPRLLDAGHGFVDTMAQYSSYGWWGGEAS FT APRGLGGMTNQYAAMPSLHVGWALWCGVMLWRHGGTRTAKAAGVVYPLVTTIVVMGTAN FT HYFLDAVAGAAVMAAGLLLTPFVLRAAARVRTRLPARFAPAAAGSANAAVPAPAPARDG FT AGSVNVSGGCQTSAGERFPRQREQRFGAGPEPDPAPSDAGDETPAPAR" FT CDS 31426..32454 FT /transl_table=11 FT /gene="SCO2808" FT /gene_synonym="2SCC13.16" FT /product="putative secreted protein" FT /note="2SCC13.16, possible secreted protein, len: 342 aa. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="InterPro:IPR016160" FT /db_xref="UniProtKB/TrEMBL:Q9F3H3" FT /protein_id="CAC10117.1" FT /translation="MDKASLASALGSPSVFGQSQFAFTRGNAFEARVKADGGAELLRLV FT HERLDRGAEPPAEAPVRVPDLSATGPEGRAARTALALREATGTPGAWTLLDHPMLALEV FT AGSPAFLEPDAVVVHPDGAWTVVEIKSFPMLDGSADPAKVGAAARQAAVYVLALERVAA FT RLDPAPRVRHRVLLVCPRDFSNLPTASAVDVRKQRAVTDRQLARLTRIEEIADALPEGV FT CFSPELPAEELTAAVEAVPATYAPECLSACELAFHCRARSREAGAVTSLGRPVRAELGG FT LSTVEDVLAAARGEAGDPDDPAVAALRRAALLRAEALATAGAGGGAAADGGIGAGGVSA FT CH" FT RBS 32474..32478 FT CDS 32481..34124 FT /transl_table=11 FT /gene="SCO2809" FT /gene_synonym="2SCC13.17" FT /product="putative membrane protein" FT /note="2SCC13.17, putative membrane protein, len: 547 aa. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9F3H2" FT /protein_id="CAC10118.1" FT /translation="MRTGRAQPAATVRHRHLSDRPLVFVPLITAGEAGAPLGALVGTDR FT DAPHLLVVPQPRDRDLRFAFLAELAGIVLPHVEAYAESVEAAERTETDPETGKRVKVEV FT DLCADAAQLVVPSRAGVDFVRLLGRSMRFRRTAEQDPETPHPAPPRVPLLGRWLTHYGE FT RARVPGSSLLLAMTDLLGRHWATGQSTLEDQHLGALLAWIAPQDPPHPRDSHEPPPTGA FT EAARRAELARDADGQLLCPPAGPATDPAFDNKLLAPAIERYDRARTALAAAEDGLEADD FT RLGALTAAEREIRALVESRTRPTWDAVWRGLDLLRALPEGAHAEERWTRDRWSFTSHRD FT RILAGEPPQPRRDDAVTAANKLATREREQARLEAQEALDDPLVMAGRRLSGEAFAGEVV FT DVVMAYSESKRPSPRPLVTIRTDDRPYLGERVKVYRSLGGKPQTAEYVGPAAPARGPGG FT PGGPDDGTGTDDGTVVLRIMDKMGRGKEPEAGSVPEKGDLVCFTLFEHEQRGGAKLPDP FT EQTPWTHGGPPGESAAVPEAADAQTEEDVL" FT RBS 34108..34113 FT CDS 34121..35482 FT /transl_table=11 FT /gene="SCO2810" FT /gene_synonym="SCBAC17F8.01" FT /gene_synonym="2SCC13.18" FT /product="hypothetical protein" FT /note="SCBAC17F8.01, unknown, len: 220aa: no significant FT database matches." FT /note="2SCC13.18, unknown (fragment), len: >268 aa" FT /db_xref="UniProtKB/TrEMBL:Q8CJY4" FT /protein_id="CAD55455.1" FT /translation="MTVKALSASAPASFDPGAEAARATAAILHDTLHGTERGVVVDSPP FT GAGKSTLVVRAALELAEAGRPLMVVAQTNAQVDDLVLRLAEKNPDLPVGRLHSSDADPY FT DKALDALGNVRKSAKAADLAGQAVVLSTAAKWAHVKVDEPWRHAIVDEAYQMRSDSLLA FT VAGLFERALFVGDPGQLDPFATVGSEQWAGLAYDPSSSAVTTLLAHNPGLPQHRLPVSW FT RLPASAARLVSDAFYPYTPFRSGTRHGDRSLAFAVPSDGSGPDRVIDEAAASGWGLLEL FT PARHTPRTDPEAVRAVAAVVRRLLDREGRATSERSPDPAPLTAARIAVGTAHRDQAAAV FT RAELAGLGVHDVTVDTANRLQGREYDVTVVLHPLSGRPDATAFHLETGRLCVLASRHRH FT ACIVVCREGVGDLLDDYPSTEPVQLGTLVKFPDGWEANHAVLAHLAEHRAAWRP" FT CDS complement(35780..36106) FT /transl_table=11 FT /gene="SCO2811" FT /gene_synonym="SCBAC17F8.02c" FT /product="putative regulator" FT /note="SCBAC17F8.02c, possible regulator, len: 220 aa: FT similar to many from Gram positives eg. TR:Q52517 FT (EMBL:M18263) MmyJ from the methylenomycin cluster of FT plasmid SCP1 from Streptomyces coelicolor (111 aa) fasta FT scores; opt: 242, Z-score: 307.2, 43.878% identity in 98 aa FT overlap and TR:BAB49625 (EMBL:AP002999) probable regulatory FT protein from Rhizobium loti (118 aa) fasta scores; opt: FT 174, Z-score: 225.5, 38.095% identity in 84 aa overlap." FT /db_xref="GOA:Q93J86" FT /db_xref="InterPro:IPR001845" FT /db_xref="UniProtKB/TrEMBL:Q93J86" FT /protein_id="CAC44274.1" FT /translation="MPPWEIPSDQLPPVAAVQKLLRALADPVRLEMVRRLAADPAGEAP FT CSDLYEGLNKSTATHHFKILVEAGAFRPVMVGPSRGHRLRRDALQEAAPGLLDALMGAL FT ARQD" FT RBS 36189..36192 FT CDS 36198..37448 FT /transl_table=11 FT /gene="SCO2812" FT /gene_synonym="SCBAC17F8.03" FT /product="putative drug efflux protein" FT /note="SCBAC17F8.03, possible drug efflux protein, len: FT 416aa: similar to many eg. TR:Q9LA76 (EMBL:AF148322) FT valanimycin-resistance protein from Streptomyces FT viridifaciens (402 aa) fasta scores; opt: 582, Z-score: FT 614.9, 32.405% identity (33.952% ungapped) in 395 aa FT overlap and TR:CAC41338 (EMBL:AJ307714) tertracycline FT resistance protein from Escherichia coli (398 aa) fasta FT scores; opt: 262, Z-score: 281.3, 28.056% identity (32.268% FT ungapped) in 360 aa overlap. Contains possible FT membrane-spanning hydrophobic regions." FT /db_xref="GOA:Q93J85" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q93J85" FT /protein_id="CAC44275.1" FT /translation="MRELSQGRRPQSWSYPALLVLLMLGQATSAIPSPLYSLYAEKWDY FT PPVLTTVVFAAYGAVAVVAILLSGALSDRYGRRPVLLVAVLLLLAGLAVFVFAAGPAYL FT VVARMLNGLGIGAIVVVGGAALLDVRPERAARSGTLTAIAFNIGIAAAALGTAALAQTG FT FHPLLLPYLTDALIGLVLLVLLLVMREPHPSPGTATVGIPRPHVPKEMRGRFTFSVLGA FT GAAWAVLGVCFSLEPSIAADAANVDGPFFGGVVIAAVTLAAACTQILSARRPARTVALV FT GDTALAVLMLAGVGAFATGNAVVIVVAVALQGGAYGLAFGGSLRHLTAGIPAERRGAVM FT SMFYLLAYGALVTPTLLVGVGATVWADTTVFFVFSVLTALLCFSAVVVERVRERRRRPA FT EAVPAPGTDVREASTAD" FT misc_feature 36234..37415 FT /note="Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter, score -81.50, E-value 0.0007" FT misc_feature 36399..36449 FT /note="PS00216 Sugar transport proteins signature 1" FT RBS 37498..37503 FT CDS 37510..38076 FT /transl_table=11 FT /gene="SCO2813" FT /gene_synonym="SCBAC17F8.04" FT /product="conserved hypothetical protein" FT /note="SCBAC17F8.04, conserved hypothetical protein, len: FT 188aa: similar to many e.g. TR:BAB48410 (EMBL:AP002996) FT MLR0926 protein from Rhizobium loti (188 aa) fasta scores; FT opt: 447, Z-score: 537.5, 38.587% identity (39.227% FT ungapped) in 184 aa overlap" FT /db_xref="GOA:Q93J84" FT /db_xref="InterPro:IPR002734" FT /db_xref="UniProtKB/TrEMBL:Q93J84" FT /protein_id="CAC44276.1" FT /translation="MRRVTYSMNVSLDGYIVDPHGAIDWADPAEEVFRFWTDEIRETGA FT HLLGRRLYETMLYWETADRDESLDAAELEWAALWKALPKVVFSRTLTTVQGTNTRLASG FT TLAEEIERLRAEPGDGDIAIGAATLAAEAAASDLIDEYRTMVHPVLVGGGTPFFPHHGR FT RVNLELVESRTFGSHVAYLRHRVTH" FT CDS complement(38239..39096) FT /transl_table=11 FT /gene="SCO2814" FT /gene_synonym="SCBAC17F8.05c" FT /product="putative methyltransferase" FT /note="SCBAC17F8.05c, possible methyltransferase, len: 285 FT aa: similar to many some of which reside within antibiotic FT biosynthetic clusters e.g. TR:Q54818 (EMBL:L35560) FT doxorubicin polyketide biosynthesis gene from Streptomyces FT peucetius (286 aa) fasta scores; opt: 258, Z-score: 287.1, FT 38.136% identity (39.130% ungapped) in 118 aa overlap, FT TR:Q9S0N6 (EMBL:AB032524) C5-O-methyltransferase AveD from FT the avermectin biosynthetic cluster of Streptomyces FT avermitilis (283 aa) fasta scores; opt: 249, Z-score: FT 277.5, 30.508% identity (34.123% ungapped) in 236 aa FT overlap and TR:AAK64748 (EMBL:AE007203) hypothetical FT protein from Rhizobium meliloti (261 aa) fasta scores; opt: FT 581, Z-score: 635.1, 41.406% identity (42.570% ungapped) in FT 256 aa overlap." FT /db_xref="GOA:Q93J83" FT /db_xref="HSSP:1UFK" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:Q93J83" FT /protein_id="CAC44277.1" FT /translation="MPDIVNTEQAQAWNGPEGAHWARNQDRWNAVNEGFDEPLLDAAGI FT TGEDRVLDLGCGSGQTTRRAALRAPRGHVLGLDLSGPMLAEARSRAEREGVANVSFAQG FT DAQVHPFGAGAFDAAVSRYGVMFFADPVAAFGNVGRALRPGGRLAFVCPADAALNGWVT FT AMASLREVLPVGDFGQPGLPGMFSLAAPDRIGDVLTAAGFAGIDVNQVQAHGTWGRDAE FT DAAEFLLGTGPGRHLMERADPTARARARGILTDHLRTHEAADGTVRLLSTSWLTTATRP FT AATA" FT misc_feature complement(38437..39051) FT /note="Pfam match to entry PF01209 Ubie_methyltran, FT ubiE/COQ5 methyltransferase family, score -100.60, E-value FT 0.00013" FT RBS complement(39102..39106) FT RBS 39119..39122 FT CDS 39130..39828 FT /transl_table=11 FT /gene="SCO2815" FT /gene_synonym="SCBAC17F8.06" FT /product="putative TetR-family transcriptional regulator" FT /note="SCBAC17F8.06, possible TetR-family transcriptional FT regulator, len: 232 aa: similar to many hypothetical FT regulators eg. TR:Q9RWD4 (EMBL:AE001929) TetR-family FT transcriptional regulator from Deinococcus radiodurans (229 FT aa) fasta scores; opt: 164, Z-score: 191.6, 34.416% FT identity (36.054% ungapped) in 154 aa overlap. Contains FT Pfam match to entry PF00440 tetR, Bacterial regulatory FT proteins, tetR family." FT /db_xref="GOA:Q93J82" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q93J82" FT /protein_id="CAC44278.1" FT /translation="MRPNCMGKCPNPAIPGTIHGVEPSRGDRSGTNERPMAPRGVATPD FT VRERLFAAAERIVERDGPGALTSRAVTTEAGCAKGLLHAHFAGFDEFVAELCLDRFAKT FT ATKARALSGIAGQGAVEHNLNTVALALFDSGGLALSGLAMTRPAAALGIREALEKGAPG FT FTAIQDAIADYLEAERELGRVARTVDPPSVALAVVGTAHHLLMTGRPDAPDPRPLVTRL FT IATLVNAPAS" FT misc_feature 39277..39417 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 22.10, E-value FT 0.00057" FT RBS 39911..39917 FT CDS 39927..41027 FT /transl_table=11 FT /gene="SCO2816" FT /gene_synonym="SCBAC17F8.07" FT /product="conserved hypothetical protein" FT /note="SCBAC17F8.07, conserved hypothetical protein, len: FT 366 aa; similar to many e.g. TR:Q9I0Z9 (EMBL:AE004676) FT hypothetical protein from Pseudomonas aeruginosa (333 aa) FT fasta scores; opt: 588, Z-score: 637.0, 47.826% identity FT (50.305% ungapped)in 345 aa overlap" FT /db_xref="GOA:Q93J81" FT /db_xref="InterPro:IPR019949" FT /db_xref="UniProtKB/TrEMBL:Q93J81" FT /protein_id="CAC44279.1" FT /translation="MPADAAEEIRGTAHGTAPVPLSVLDLVTVGAGRTATDALRTGVDI FT VRLAEARGFQRYWVAEHHSMPGVASSSPAVILAHLAAHTDRIRLGSGGVMLPNHAPLVI FT AEQFGTLEAMAPGRVDLGLGRAPGTDGATAAALRRTDRLNEGADDFPQQLAELIRFLDD FT DFPDGHPYARIHAVPGPVQATSPGGVQSAHRPPVWLLGSSGFSARLAGTLGLPFAFAHH FT FSAQNTIPALDLYRESFRPSAVLDAPYALIGVSALATDDEKEARRQVLAAALNMVRLRT FT GRPGLVPTPEEAEAYDFSPMEQDFIQSWNANVIHGTADEVRSGLDDLHKRTGADELMLT FT ANAHGGDVRLRSYELIADAYGLPTPA" FT CDS complement(41003..42907) FT /transl_table=11 FT /gene="SCO2817" FT /gene_synonym="SCBAC17F8.08c" FT /product="conserved hypothetical protein" FT /note="SCBAC17F8.08c, conserved hypothetical protein, len: FT 634 aa: similar in regions to many proteins of varying FT lengths e.g. TR:Q9RCY2 (EMBL:AL133469) hypothetical protein FT SCM10.16c from Streptomyces coelicolor (714 aa) fasta FT scores; opt: 1259, Z-score: 1358.4, 43.960% identity FT (46.454% ungapped) in 596 aa overlap and TR:Q9HVI8 FT (EMBL:AE004874) hypothetical protein from Pseudomonas FT aeruginosa (1415 aa) fasta scores; opt: 961, Z-score: FT 1032.5, 36.825% identity (40.250% ungapped) in 611 aa FT overlap. Contains Pfam match to entry PF00563 EAL, Domain FT of unknown function and Pfam match to entry PF00990 GGDEF, FT GGDEF domain" FT /db_xref="GOA:Q93J80" FT /db_xref="InterPro:IPR013656" FT /db_xref="UniProtKB/TrEMBL:Q93J80" FT /protein_id="CAC44280.1" FT /translation="MNGTSEGPAPAADLGPAITESDEGLAPRAVRTEPPAYRSVFTTAP FT LAMAVVDAEGLVVSANDTLGTLLGTDPDALAGSVAADLVDLASDAGTWHAYREVLRGHR FT PRLRCTRRLKRADGHSLWAQVTVEPLAGPGGSGGSGDGDAPGLLLSVADVSARRELQAR FT LRHLQMHDPVTRLPNRALFFERLTAALEAESYEHGGTGRIGVCYLDLDGFKAVNDTHGH FT RVGDRLLAAVAERLTRCAEEAAHARSGAPLVARLGGDEFALLVEDSTGTDQLADLAGAV FT LAALQPPFELSDRRLSVTASVGVVERHTAGTTPTALMQAADTTLYWAKADGRARWTLFD FT PERNANRMTRQALAATLRPAIERGEFALEYQPLVGMEDGRVRGVEALIRWNHPQFGVLA FT PNRFIALAEEDGSIVPLGRWILRTACHQARRWQLAHPDEPPIFVSVNVAVRQVWDSDLV FT ADVARTLEETGLAPELLQLELTESAVMGSAGRPLQVLKALSDMGVHIAIDDFGTGYSNL FT AYLSRLPVSVLKLDGAFVRGFQYDAVSDAAACGAGGANPADEVIVEAMVQLAHRLGLTV FT TAECVETSAQATRLRRIGCDTGQGWLYSRPVAPDRISALLGHAGPGGPAGVQAGVGNP" FT misc_feature complement(41075..41863) FT /note="Pfam match to entry PF00563 EAL, Domain of unknown FT function 2, score 292.50, E-value 5.4e-84" FT misc_feature complement(41903..42427) FT /note="Pfam match to entry PF00990 GGDEF, GGDEF domain, FT score 176.80, E-value 3.6e-49" FT RBS complement(42914..42917) FT CDS 43192..44502 FT /transl_table=11 FT /gene="SCO2818" FT /gene_synonym="SCBAC17F8.09" FT /product="conserved hypothetical protein" FT /note="SCBAC17F8.09, hypothetical protein, len: 436 aa: FT similar TR:Q9Z4X3 (EMBL:AL035654) putative secreted protein FT SCE8.01 from Streptomyces coelicolor (432 aa) fasta scores; FT opt: 555, Z-score: 609.9, 33.991% identity (38.945% FT ungapped) in 456 aa overlap" FT /db_xref="InterPro:IPR017683" FT /db_xref="UniProtKB/TrEMBL:Q93J79" FT /protein_id="CAC44281.1" FT /translation="MHKLGAVSRQPRPEVHVPRQLPRTRLRSTAAVCTTMSALAATSLI FT TAPSVAEPFSPEPCALQRTAVHHSEGLDTWNATYPRPARTLDAVMVFLSFPDSQPLTAP FT AELAADHFPATGDFFRRASYGAFTLRPHPLRDWIRMPSPSTSYAIRRDWSPEHRAAYLR FT DALTAADRYVDFSRYDVVYFVADPDAPGVDSDATKVVNLDTPLRADGTDIRRVVTVFEN FT HPPDRLVLAHETGHVFDLPDLYHRPADGEGDWDTHVGDWDLMGSQFGLSPDLFGWHKWK FT LGWLRPRQVACVRGSEPTRLTLEPLGAGPGVVVTGAAGAPAFGLGRGTKLAVVRTGAGS FT ALAFEVRTPVGNDAASCRAGVLVYRVHSGAESGGGPIEVVDAHPDTEACWADSVYPPLA FT DAPVSLGESFTVPGDGVRVEVEDRTESGTWTVQITPG" FT tRNA complement(44675..44748) FT /note="tRNA Lys Anticodon CTT. Score 87.71" FT CDS complement(44739..45353) FT /transl_table=11 FT /gene="SCO2819" FT /gene_synonym="SCBAC17F8.10c" FT /product="hypothetical protein" FT /note="SCBAC17F8.10c, hypothetical protein, len: 204 aa: FT similar to many eg. TR:Q9X8N0 (EMBL:AL049628) hypothetical FT protein SCE94.25 from Streptomyces coelicolor (233 aa) FT fasta scores; opt: 250, Z-score: 267.4, 36.709% identity FT (39.726% ungapped) in 158 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q93J78" FT /protein_id="CAC44282.1" FT /translation="MSSTRNATPHASDVTSDGAAWLASAGAYPRSTLALWEERPEAPVV FT LPCGSTFDVVSAPAIFGRRMLDRLWDDGPGSGPVAEFRGRMLLFAAPGTAQRLPSLLDW FT EEWSTRGREGGRAGAVPPLLCHGAGDAVTVPAPAGPAAPADAPPRSGSRWLVAPDTRRP FT WLPGPEIMLWAAVRAARAAVRISIFPPADQDAKVYDVSRRR" FT CDS complement(45495..45842) FT /transl_table=11 FT /gene="SCO2820" FT /gene_synonym="SCBAC17F8.11c" FT /product="hypothetical protein" FT /note="SCBAC17F8.11c, hypothetical protein, len: 115 aa: no FT significant database matches." FT /db_xref="UniProtKB/TrEMBL:Q93J77" FT /protein_id="CAC44283.1" FT /translation="MAEPTPRRHEPRLRPAPLLFEPAEAAADPEHFFDLESIDDPRALL FT ERATELTHAFRAAADRAMEFQAIAAAQLADPRRFDRLTAADIAERAEWTEDYAKKMVEF FT GQDLMRGESAE" FT RBS complement(45850..45855) FT CDS complement(45994..47559) FT /transl_table=11 FT /gene="SCO2821" FT /gene_synonym="SCBAC17F8.12c" FT /product="putative secreted pectate lyase" FT /note="SCBAC17F8.12c, possible secreted pectate lyase, len: FT 521 aa: similar to many e.g. TR:Q9KGY6 (EMBL:AF278705) FT pectate lyase B from Alteromonas haloplanktis (658 aa) FT fasta scores; opt: 1744, Z-score: 1590.1, 63.301% identity FT (65.859% ungapped) in 515 aa overlap and SW:P04959 FT (PELB_ERWCH) pectate lyase B from Erwinia chrysanthemi (375 FT aa) fasta scores; opt: 413, Z-score: 386.2, 29.167% FT identity (32.464% ungapped) in 384 aa overlap. Contains FT Pfam match to entry PF00544 pec_lyase, Pectate lyase and a FT probable N-terminal signal sequence." FT /db_xref="GOA:Q93J76" FT /db_xref="HSSP:1AIR" FT /db_xref="InterPro:IPR012334" FT /db_xref="UniProtKB/TrEMBL:Q93J76" FT /protein_id="CAC44284.1" FT /translation="MRRPVALRLQAALGTLALAAAAGVVLTMPEAAAAAGGATGYATQN FT GGTTGGAGGQTVRATTGTAIHEALCGRADSSTPITIEVEGTINHGNTSKVSGDSCNTAA FT DRIELKQVSNITIVGVGNGAVFDQLGIHIRESSNIIIQNVTVRNVKKSGSPTSNGGDAI FT GMESDVRNVWVDHSTLEASGGESEGYDGLFDMKDNTQYVTLSYSVLRNSGRGGLIGSSE FT SDTSNGYVTFHHNLYENIDSRAPLLRGGTAHMYNNHYVSLNKSGINSRAGAKAKVDNNY FT FEDSKDVLGTFYTDAAGFWQVSGNIFDNVTWSEPGGDNNPAGPDPQSNTTVSIPYSYGL FT DDASCVPSVVSGTAGANKGLKVSDGSCTPQSPDPTDPTDPDPTDPDPTDPTDPDPTDPP FT SGTNLSVGAGSDGSSKASGTSYGNVRDGDLGTYWSPAGTTGSISVKWSSATTVGKINIR FT EAAGSEGTVGSYRVVNHDTGAVLASGSGAGVIGFSPVSLEKITFEITGASGTPKIAEFE FT TYAG" FT misc_feature complement(46483..47523) FT /note="Pfam match to entry PF00544 pec_lyase, Pectate FT lyase, score 48.10, E-value 4.4e-12" FT RBS complement(47567..47570) FT CDS complement(47980..48711) FT /transl_table=11 FT /gene="SCO2822" FT /gene_synonym="SCBAC17F8.13c" FT /product="putative decarboxylase" FT /note="SCBAC17F8.13c, possible decarboxylase, len: 243 aa: FT similar to many e.g. SW:Q05115 (AMDA_BORBR) arylmalonate FT decarboxylase from Alcaligenes bronchisepticus (240 aa) FT fasta scores; opt: 258, Z-score: 293.3, 33.333% identity FT (34.302% ungapped) in 177 aa overlap. Almost identical to FT TR:Q54412 (EMBL:X52071) hypothetical protein which close FT alongside transfer RNA-gly in Streptomyces lividans (195 FT aa) fasta scores; opt: 1233, Z-score: 1358.6, 98.980% FT identity (99.487% ungapped) in 196 aa overlap. Also similar FT to neighbouring CDS SCBAC17F8.14c." FT /db_xref="InterPro:IPR015942" FT /db_xref="UniProtKB/TrEMBL:Q93J75" FT /protein_id="CAC44285.1" FT /translation="MTALGFLYPGHSGEDDYPRIEQLLGSDIRVDLVHTDIGEDAHRVD FT ALLEMGSPRRLEAGVAELRLAGADAVVWACTSGSFVHGWDGAHAQVRALAQAAGLPASS FT TSFAFVHAAKELGVRRVSIGATYPDDVARLFGDFLGAAGIEVADVVSSGIITAAEVGTW FT TEAEVLALARAADRPDVEAVLLPDTALHTAAHIPALEKELGKPVLTANQVTIWEGLRLA FT DRRVNAPELGALFTREPVVQA" FT CDS complement(48708..49610) FT /transl_table=11 FT /gene="SCO2823" FT /gene_synonym="SCBAC17F8.14c" FT /product="putative decarboxylase" FT /note="SCBAC17F8.14c, possible decarboxylase, len: 300 aa: FT similar to many e.g. SW:Q05115 (AMDA_BORBR) arylmalonate FT decarboxylase from Alcaligenes bronchisepticus (240 aa) FT fasta scores; opt: 328, Z-score: 331.2, 33.810% identity FT (35.323% ungapped) in 210 aa overlap and TR:Q54412 FT (EMBL:X52071) hypothetical protein which close alongside FT transfer RNA-gly in Streptomyces lividans (195 aa) fasta FT scores; opt: 295, Z-score: 300.7, 36.872% identity (38.824% FT ungapped) in 179 aa overlap. Also similar to neighbouring FT CDS SCBAC17F8.13c." FT /db_xref="InterPro:IPR015942" FT /db_xref="UniProtKB/TrEMBL:Q93J74" FT /protein_id="CAC44286.1" FT /translation="MDISFLGGPAPQRGVGVVAPFDFALDRELWRWVPDDVSLHMTRTP FT FVPVEVSLDLARMVSEHETLGEAVRTLNAIAPEVVAYACTSGSFVGGIAGERAMCEAMT FT WAGAVPSVTTSGALLDALAELGVRRVALVTPYTVSVTRALEAYVAEAGVTVTGCAFMGL FT TRHIWKVPYRDVADMARQAVPAPGAADALFISCTNLPTYDVIPQLEAELRIPVISANQV FT TMWAALRRLGTPAVGPYQALTDPAARLGPAATGAVGPAVVGPPGPVDPAVAGPVGPAAV FT DMPGVGDVPDTEQQQEGWT" FT CDS 49798..50781 FT /transl_table=11 FT /gene="SCO2824" FT /gene_synonym="SCBAC17F8.15" FT /product="putative NAD-binding protein" FT /note="SCBAC17F8.15, possible NAD-binding protein, len: FT 327aa: similar to many predicted dehydrogenases eg. FT TR:Q9KEA4 (EMBL:AP001510) D-3-phosphoglycerate FT dehydrogenase from Bacillus halodurans (316 aa) fasta FT scores; opt: 523, Z-score: 556.0, 33.808% identity (35.055% FT ungapped) in 281 aa overlap. Contains Pfam match to entry FT PF02826 2-Hacid_DH_C, D-isomer specific 2-hydroxyacid FT dehydrogenase, NAD binding domain but does not contain the FT corresponding catalytic domain." FT /db_xref="GOA:Q93J73" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q93J73" FT /protein_id="CAC44287.1" FT /translation="MTTSPRTPAPAPTPPPTLLVLDAEPPPRLGRLTGRARIEHADAAT FT LAERLPHADVLLVWDFASHAVREAWPGGGPRPRWVHTASAGVDHLMCPELAESDTVVTN FT ARGVFDRPIAEYVAALVLAMAKDLPTTLRLQGERTWRHRESTRVAGTRACVVGSGPIGR FT AIASTLEALGITTALAGRTARPGVHGPEDLDRLLAGADWVVAAAPLTDDTRGMFDARRF FT ALLRPSARFVNVGRGQLVVEDDLVEALAARRIAGAALDVLSHEPLSPDSALWEVPGLIV FT SPHMSGDTIGWRDELGAQFVELFESWAAGGPLANVVDKKRGYVPGH" FT misc_feature 50134..50649 FT /note="Pfam match to entry PF02826 2-Hacid_DH_C, D-isomer FT specific 2-hydroxyacid dehydrogenase, NAD binding domain, FT score 104.70, E-value 1.7e-27" FT RBS 50806..50810 FT CDS 50818..52221 FT /transl_table=11 FT /gene="SCO2825" FT /gene_synonym="SCBAC17F8.16" FT /product="putative amidase" FT /note="SCBAC17F8.16, possible amidase, len: 467 aa: similar FT to many e.g. TR:Q9ZHK8 (EMBL:AF058285) pyrazinamidase from FT Mycobacterium smegmatis (468 aa) fasta scores; opt: 767, FT Z-score: 783.4, 34.573% identity (35.666% ungapped) in 457 FT aa overlap and SW:Q9Z580 (GATA_STRCO) glutamyl-tRNA FT amidotransferase subunit A SC8D9.11 from Streptomyces FT coelicolor (497 aa) fasta scores; opt: 628, Z-score: 642.1, FT 33.128% identity (35.698% ungapped) in 486 aa overlap. FT Contains Pfam match to entry PF01425 Amidase, Prosite match FT to PS00017 ATP/GTP-binding site motif A (P-loop) and FT PS00571 Amidases signature" FT /db_xref="GOA:Q93J72" FT /db_xref="HSSP:1M22" FT /db_xref="InterPro:IPR000120" FT /db_xref="UniProtKB/TrEMBL:Q93J72" FT /protein_id="CAC44288.1" FT /translation="MTDLTELTAVQLVDGYRKGAFSPVEATRAVLERAERIQPEVNAFV FT RLTGEEALDQARRAEERWRRGEPCGRLDGVPVTVKDILLTRGQPTLRGSRAVSPDGPWD FT EDAPSVARLREHGAVFVGKTTTPEYGWKGVTDSPLSGVTRNPHDPSRTAGGSSGGAAAA FT VALGAGPLALGTDGGGSVRIPASFCGIFGLKPTYGRVPLYPASAFGTLAHVGPMTRDAA FT DAALMLDVVGTPDARDWSALGPASGSYTEALSGGVRGLRVAYSPTLGGQVAVRPAVAGA FT VRRAVERLAELGAYVTEADPDFTDPVDAFHTLWFSGAARVVQHLRAGQRELLDPGLREI FT VGAGARYSALDYLAAVDVRMELGRRMGVFHGSYDLLVTPTLPVTAFEAGVEVPKGSGYR FT RWTGWTPFTYPFNLTQQPAATVPVGTDGDGLPVGLQIVAARHRDDLVLRTAHALYGAET FT ALVTARSAG" FT misc_feature 50890..52158 FT /note="Pfam match to entry PF01425 Amidase, Amidase, score FT 415.60, E-value 4.6e-121" FT misc_feature 51166..51189 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 51277..51372 FT /note="PS00571 Amidases signature" FT CDS 52242..52715 FT /transl_table=11 FT /gene="SCO2826" FT /gene_synonym="SCBAC17F8.17" FT /product="hypothetical protein" FT /note="SCBAC17F8.17, hypothetical protein, len: 157 aa: no FT significant database matches." FT /db_xref="UniProtKB/TrEMBL:Q93J71" FT /protein_id="CAC44289.1" FT /translation="MAATVIALGSLWVSWAQTRAARLHNRQSVRPLLRIRRIRQDDMVG FT LKLVNAGLGPAVVTRSVVRLDGAAAGEWNREVKGALFTPELWPKTYSLRAGSVVLAGQE FT TFLVLLDRSRSTGSDRLQEFWGLIDRRLVIEVEYESLYGGEGFSVSSATPGGS" FT CDS complement(52696..53199) FT /transl_table=11 FT /gene="SCO2827" FT /gene_synonym="SCBAC17F8.18c" FT /product="hypothetical protein" FT /note="SCBAC17F8.18c, hypothetical protein, len: 167 aa: no FT significant database matches." FT /db_xref="UniProtKB/TrEMBL:Q93J70" FT /protein_id="CAC44290.1" FT /translation="MEGMADRYIEVSLVKRGITCTAQLLDDRAPITCAAVWDALPLGGD FT VYHAKYARNEIYALFPPFATSEPPLENPTVTPIPGDLCYFAFAGAELGTKAYGYDREVR FT PGTTLVDLALFYERNNLLLNGDVGWVPGTVWGRITEGLDTMAEACNDLWRTGAAGETLS FT FRRA" FT CDS 53298..54227 FT /transl_table=11 FT /gene="SCO2828" FT /gene_synonym="SCE20.02" FT /product="probable amino acid ABC transporter protein, FT solute-binding component." FT /note="SCE20.02, probable amino acid ABC transporter FT protein, solute-binding component, len: 309 aa. Similar to FT several including: Salmonella typhimurium FT SW:ARGT_SALTY(EMBL:V01368) FT lysine-arginine-ornithine-binding periplasmic protein FT precursor (260 aa), fasta scores opt: 251 z-score: 294.5 FT E(): 5.1e-09 25.8% identity in 279 aa overlap and Rhizobium FT sp. (strain NGR234) SW:Y4TE_RHISN(EMBL:AE000098) probable FT amino-acid ABC transporter periplasmic binding protein Y4TE FT (300 aa), fasta scores opt: 599 z-score: 691.7 E(): 3.8e-31 FT 35.4% identity in 297 aa overlap. Contains a Pfam match to FT entry PF00497 SBP_bac_3, Bacterial extracellular FT solute-binding proteins, family 3. Also contains an FT N-terminal possible membrane spanning hydrophobic domain." FT /db_xref="GOA:Q9RDC3" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q9RDC3" FT /protein_id="CAB65558.1" FT /translation="MAPPHRTPPWGISDQRPRTAGPTRRSLLAGVAALGALGAAGCSRV FT ATASDVKGGDLLDRLRAQGVARLGIAGEVPFGYIDKNGELTGEAPELAKVIFKRLGVDR FT VQPVPTEFGSLIPGLASQQFDVVAAGMYINPDRCQQVIFSDPDYQMLDAYIVRKGNPLG FT LHNYRDVVKKKAKFATGTGYAEIAYAVEHGYKEDDILIVPDQVAGLNAVESGRVDVFAG FT TALTVRDVVKKSSKAEATEAFAPLVDGKPHVDGGGFAFRPDETNLRDAFNVELQKLKKS FT GELLRILKPFGFTQNEMTDLTAKELCGG" FT misc_feature 53364..54173 FT /note="Pfam match to entry PF00497 SBP_bac_3, Bacterial FT extracellular solute-binding proteins, family 3, score FT 77.30, E-value 3.2e-19" FT CDS 54224..54925 FT /transl_table=11 FT /gene="SCO2829" FT /gene_synonym="SCE20.03" FT /product="probable amino acid ABC transporter protein, FT integral membrane component." FT /note="SCE20.03, amino acid ABC transporter protein, FT integral membrane component, len: 233 aa. Highly similar to FT many including: Escherichia coli SW:GLNP_ECOLI(EMBL:X14180) FT glutamine transport system permease protein GlnP (219 aa), FT fasta scores opt: 377 z-score: 445.7 E(): 1.9e-17 27.8% FT identity in 212 aa overlap and Rhizobium sp. (strain FT NGR234) SW:Y4TF_RHISN(EMBL:AE000098) probable amino-acid FT ABC transporter permease protein Y4TF (238 aa), fasta FT scores opt: 570 z-score: 667.5 E(): 8.5e-30 45.1% identity FT in 204 aa overlap. Contains a Pfam match to entry PF00528 FT BPD_transp, Binding-protein-dependent transport systems FT inner membrane component. Also contains a possible FT N-terminal signal sequence and possible membrane spanning FT hydrophobic domains." FT /db_xref="GOA:Q9RDC2" FT /db_xref="InterPro:IPR010065" FT /db_xref="UniProtKB/TrEMBL:Q9RDC2" FT /protein_id="CAB65559.1" FT /translation="MTSGLWELVLQGVWVTVQLLFFSSLLATAVSFVVGIARSHRLWIV FT RFLAGFYTEVFRGTSALVMIFWVFFVLPPAFGWQLVPMWAGTLALGLTYGAYGSEIVRG FT SLAAVDPAQKEGGIALSFTPWQRMKLILLPQAVPEMIPPFSNLLIELLKGTALVSIMGM FT GDLAFSANLVRLALQESAEIYTYVLLIYFVIAFLLTRVMRGLEKKLKAGVGKAPKKKTA FT AVRVPEGSGVS" FT misc_feature 54536..54766 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 44.30, E-value 2.7e-09" FT CDS 54922..55572 FT /transl_table=11 FT /gene="SCO2830" FT /gene_synonym="SCE20.04" FT /product="probable amino acid ABC transporter protein, FT integral membrane component." FT /note="SCE20.04, probable amino acid ABC transporter FT protein, integral membrane component, len: 216 aa. Highly FT similar to several ABC transporter permeases including: FT Escherichia coli SW:GLNP_ECOLI(EMBL:X14180) glutamine FT transport system permease protein GlnP (219 aa), fasta FT scores opt: 378 z-score: 454.8 E(): 6e-18 33.2% identity in FT 217 aa overlap and Rhizobium sp. (strain NGR234) FT SW:Y4TG_RHISN(EMBL:AE000098) probable amino-acid ABC FT transporter permease protein Y4TG (231 aa), fasta scores FT opt: 667 z-score: 792.8 E(): 0 47.6% identity in 208 aa FT overlap. Contains multiple possible membrane spanning FT hydrophobic domains and a Pfam match to entry PF00528 FT BPD_transp, Binding-protein-dependent transport systems FT inner membrane component." FT /db_xref="GOA:Q9RDC1" FT /db_xref="InterPro:IPR010065" FT /db_xref="UniProtKB/TrEMBL:Q9RDC1" FT /protein_id="CAB65560.1" FT /translation="MKWDWSAVSDFMPHFWDGLLVTLQILVLGSLVSFGLGLVWALLMR FT VPSRWVTWPVGVVTEFVRNTPLLVQLFFLFYVLPEWNITFSALTTGVVAIGLHYSTYTM FT QVYRAGIEGVPVGQWEAATALNLPMRRTWTAVILPQAIRRVTPALGNYVISMLKDTPLL FT MAITVLEMLGEARLFSQQNFQFTEPLTVIGVAFIVISYLASLALRALERRLAH" FT misc_feature 55249..55470 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 37.50, E-value 3.1e-07" FT CDS 55562..56347 FT /transl_table=11 FT /gene="SCO2831" FT /gene_synonym="SCE20.05" FT /product="probable amino acid ABC transporter protein, FT ATP-binding component." FT /note="SCE20.05, probable amino acid ABC transporter FT protein, ATP-binding component, len: 261 aa. Highly similar FT to many ATP-binding transport protein including: Bacillus FT stearothermophilus SW:GLNQ_BACST(EMBL:M61017) glutamine FT transport ATP-binding protein GLNQ (242 aa), fasta scores FT opt: 758 z-score: 851.7 E():0 47.5% identity in 242 aa FT overlap and Thermotoga maritima TR:Q9WZ60(EMBL:AE001734) FT amino acid ABC transporter, ATP-binding protein (242 aa), FT fasta scores opt: 829 z-score: 930.4 E(): 0 54.5% identity FT in 242 aa overlap. Also similar to several other FT Streptomyces coelicolor transport proteins e.g. FT TR:O50495(EMBL:AL020958) glutamate uptake system FT ATP-binding protein, GluA (258 aa), fasta scores opt: 775 FT z-score: 683.3 E(): 1.1e-32 48.2% identity in 251 aa FT overlap. Contains Prosite hits to PS00211 ABC transporters FT family signature and PS00017 ATP/GTP-binding site motif A FT (P-loop). Also contains a Pfam match to entry PF00005 FT ABC_tran, ABC transporter." FT /db_xref="GOA:Q9RDC0" FT /db_xref="HSSP:1B0U" FT /db_xref="InterPro:IPR014343" FT /db_xref="UniProtKB/TrEMBL:Q9RDC0" FT /protein_id="CAB65561.1" FT /translation="MPTDTLPNPEKSPERSSGELIRLEQVTKRFGDNTVLDHLDFSVDA FT GKHVTLIGPSGSGKTTILRLLMTLLKPDEGTITVDGQKLFPATEKERREVRKQIGMVFQ FT QFNLFPNMSVLRNITEAPVTVLGMPKDEAVERAKGLLDMVGLADKCDARPAQLSGGQQQ FT RVAIARALAMRPKVLLLDEVTSALDPELVAGVLDLLRDIARSTDITMLCVTHEMNFARD FT ISDQVLMFDSGRVIEAGAPEKIFSEPEHDRTREFLSAVL" FT misc_feature 55718..55741 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 55760..56260 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 149.60, E-value 5.4e-41" FT misc_feature 56030..56074 FT /note="PS00211 ABC transporters family signature" FT CDS 56430..57287 FT /transl_table=11 FT /gene="SCO2832" FT /gene_synonym="SCE20.06" FT /product="putative IclR-family transcriptional regulator." FT /note="SCE20.06, possible IclR-family transcriptional FT regulator, len: 285 aa, Almost identical to a gene fragment FT which, like SCE20.06, is located upstream of the FT Streptomyces lividans lysT tRNA gene: FT TR:Q54411(EMBL:X52073) (200 aa), fasta scores opt: 1250 FT z-score: 1464.9 E():0 99.5% identity in 200 aa overlap. FT Also similar to Streptomyces coelicolor FT TR:Q9X9U3(EMBL:AL096823) putative transcriptional regulator FT (241 aa), fasta scores opt: 597 z-score: 704.2 E(): 7.7e-32 FT 43.2% identity in 236 aa overlap. Contains a Pfam match to FT entry PF01614 IclR, Bacterial transcriptional regulator FT with a putative helix-turn-helix motif situated between FT residues 41..62 (+3.07 SD)." FT /db_xref="GOA:Q9RDB9" FT /db_xref="InterPro:IPR005471" FT /db_xref="UniProtKB/TrEMBL:Q9RDB9" FT /protein_id="CAB65562.1" FT /translation="MRAPKSAQHPLPGSLLAAIVNAGMHQRAQGETTVALQHKPTAPHH FT STEDALRVLETVARHTSGVTDTEIARESGIGTERLTTLLRMLRREAYVEQTADGAYVTG FT EALARLGSAQGREQALREKLQRTLEGLRDSVGAAVYISRYVDGEVSVTQYADSPAAPRV FT NEWVDFRVSAHATAVGKSLLTQLDHAGRRDHLARHRMARLTSRTITSDKLLLSRLESQP FT ATVPVLDLQEYAVGTVCAAVPITAGSAVGCLALSLPVEHAHRLRRAADELNRSAAPVLL FT SLAI" FT misc_feature 56730..57254 FT /note="Pfam match to entry PF01614 IclR, Bacterial FT transcriptional regulator, score 21.90, E-value 6e-08" FT tRNA 57377..57450 FT /note="tRNA Lys anticodon CTT" FT CDS complement(57496..58101) FT /transl_table=11 FT /gene="SCO2833" FT /gene_synonym="chb" FT /product="secreted chitin binding protein." FT /note="SCE20.07c, chb, secreted chitin binding protein, FT len: 201 aa. Highly similar to several including: FT Streptomyces olivaceoviridis (Streptomyces corchorusii) FT TR:Q54501(EMBL:X78535) chitin binding protein precursor FT Chb1 (201 aa), fasta scores opt: 1185 z-score: 1303.0 E():0 FT 83.7% identity in 202 aa overlap and Streptomyces reticuli FT TR:O87962(EMBL:Y14315) chitin binding protein (Chb2) (201 FT aa), fasta scores opt: 1161 z-score: 1276.8 E(): 0 79.1% FT identity in 201 aa overlap. Contains a possible N-terminal FT signal sequence." FT /db_xref="GOA:Q9RDB8" FT /db_xref="InterPro:IPR004302" FT /db_xref="UniProtKB/TrEMBL:Q9RDB8" FT /protein_id="CAB65563.1" FT /translation="MRTRTKLYAAALGMATTGALVLSSGGASGHGYTDLPVSRQKVCQN FT GTVGGCGAIQWEPQSVEGPKGFPASGPADGTICSAGHGSFAALDSPKQPNGQAWPTTRV FT NGGQSYTFRWQFTARHATTDFKYYVTKPGWNQNHNLARSDLNLTPFFTVPYGGKQPPAT FT LSHSGTLPSGLSGHHVILAVWTVHDTGNAFYACSDVTF" FT CDS complement(58222..59373) FT /transl_table=11 FT /gene="SCO2834" FT /gene_synonym="SCE20.08c" FT /product="putative membrane protein" FT /note="SCE20.08c, possible membrane protein, len: 383 aa; FT C-terminal region similar to TR:Q9KIM1 (EMBL:AF230489) FT Streptomyces coelicolor F42A (putative integral membrane FT protein) or SCK7.11c, 312 aa; fasta scores: opt: 467 FT Z-score: 441.6 E(): 5.8e-17; 31.229% identity in 301 aa FT overlap. Contains possible membrane spanning hydrophobic FT domains" FT /db_xref="InterPro:IPR001107" FT /db_xref="UniProtKB/TrEMBL:Q9RDB7" FT /protein_id="CAB65564.1" FT /translation="MSTTSSTNPETAPAAPEESAAAAGQRSARLIHNEATTEIPVHLLF FT RDDPDPAPVPLRPAVVARRPGPGERTGARPGARRPVAARPRPAPQVDPELTERPGRVLP FT GAAGVAAGLCGAAGCAATSWWAGLVPPLAAQALGLPAYAGAGLGPAQWAAYAAAGALGM FT FGFGGLARGRTGRAWVLGLFGRYRGTVRRTGLMWVNPLLLRRRVDVRLRHWRSEPMPAA FT DGNGVALRAVTLVVWRVRDTAKATLGVEDHETYLRECVEAALARVPVEPLGTVRSSADV FT AGDTLTRLVAADAAPVGLEVFSVRPVRVEYAPEVAAAMHRRRIAALDAAQRASVLTSVV FT DSVEDTVTRLTMRGLVELDDYERKVLVKDLTVAFCAGRGDTGH" FT CDS complement(59430..60491) FT /transl_table=11 FT /gene="SCO2835" FT /gene_synonym="SCE20.09c" FT /product="putative membrane protein." FT /note="SCE20.09c, possible membrane protein, len: 353 aa. FT Contains a possible membrane spanning hydrophobic domain FT and is rich in the amino acid Ala." FT /db_xref="GOA:Q9RDB6" FT /db_xref="UniProtKB/TrEMBL:Q9RDB6" FT /protein_id="CAB65565.1" FT /translation="METPVFEEIEPASDCDCAGCRHWRRVLPHAPAGRALAHPAAYRTL FT VAAAAAASATAVSVLGAGGAAALPAAAHAAHRPGVPAGDEPGTPQGPRGPLHGPVGRPA FT APPAGAELAGITRTEIIDRAKSWVAAKVPYSLTAYWSDGYRQDCSGFVSMAWKLPANEW FT TGSLGTVADRITKEELQPGDILLFHNESDPQKGSHVVIFGGWTDGTRTAYTAYEQTPPH FT TRKLDTPYAYWSNSAQYLPYRYKGVAAGDVAKAGAAGTEEAPPGAAGPASHGVAGYPGR FT AMFRPGADNPYVTRLGRQLVRKGFGTYYTRGPGPRWGEADRRGVQAFQRAQGWRGGAAD FT GYPGPETWRRLFS" FT tRNA 60689..60765 FT /note="tRNA Lys anticodon CTT" FT CDS 61056..63017 FT /transl_table=11 FT /gene="SCO2836" FT /gene_synonym="SCE20.10" FT /product="putative glycosyl transferase" FT /note="SCE20.10, possible glycosyl transferase., len: 653 FT aa. Weakly similar to several other putative glycosyl FT transferases e.g. Aquifex aeolicus TR:O67406 FT (EMBL:AE000738) cellulose synthase catalytic subunit (759 FT aa), fasta scores opt: 326 z-score: 359.1 E(): 1.3e-12 FT 22.0% identity in 590 aa overlap. Contains a Pfam match to FT entry PF00535 Glycos_transf_2, Glycosyl transferases and FT multiple possible membrane spanning hydrophobic domains" FT /db_xref="GOA:Q9RDB5" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q9RDB5" FT /protein_id="CAB65566.1" FT /translation="MTSTPTGAGPDHDPSQTTQLRVPGHRNWNTGSFRRIKKTLPKYDY FT EHYSRLAGPLTQPDPNKPYRVQYRSLISQEPHRLRVALMLAAAPLLSVVLLVWLLQPEH FT WTERDYVAFDWLPALDIVMLVAIGLIELFRCLNVLSNAHATLVARDPVPVVPETGTKVA FT FLTSFVPGKEPLEMVTKTLEAAVRIRHRGLMHVWLLDEGDDPEVKEVCARLGVHHFSRK FT GVAKWNRKKGPHRAKTKHGNYNAWLDAHGDDYDFFASVDTDHVPLPNYLERMLGFFRDP FT DVGFVIGPQVYGNYDNPITKAAESQQFLFHALIQRAGNRYGGPMFVGTSNAVRIRALKQ FT IGGLYDSITEDMATGFEMHRHKNPATGRKWRSVYTPDVLAVGEGPNAWTDFFTQQMRWS FT RGTYETILKQYWKGWYSLPPSKLFNYTMMIIFYPMSALNWILAALSCCLFLGLGASGVN FT IDPAVWLMLYGNASALQIGLYVWNRRHNVSPHEPEGSGGVAGMIMSALSAPLYAKALID FT SVLRRKSKFVVTPKGDSASPDTLFGTFRYHWYFIVIFGGSIAAGFVYGHSHPAMIIWAT FT FALLITASPMFAWRHELRKAKKQPPVAAAEPAPRVPPQQAPYGRHTPQHRPDWAAPADG FT GDDQTMQIALGGLGGRKE" FT misc_feature 61551..62081 FT /note="Pfam match to entry PF00535 Glycos_transf_2, FT Glycosyl transferases, score 14.20, E-value 0.01" FT CDS 63014..64951 FT /transl_table=11 FT /gene="SCO2837" FT /gene_synonym="SCE20.11" FT /product="putative secreted protein." FT /note="SCE20.11, possible secreted protein, len: 645 aa. FT Weakly similar to a Eukaryotic galactose oxidase precursor FT (EC 1.1.3.9) from Dactylium dendroides (Cladobotryum FT dendroides) SW:GAOA_DACDE(EMBL:M86819) (680 aa), fasta FT scores opt: 350 z-score: 374.4 E(): 1.8e-13 26.8% identity FT in 400 aa overlap. Contains a possible N-terminal signal FT sequence." FT /db_xref="InterPro:IPR011498" FT /db_xref="UniProtKB/TrEMBL:Q9RDB4" FT /protein_id="CAB65567.1" FT /translation="MKDRAGRRRARRFAIGTAVVVALAGMNGPWLYRFSTEKYHQYKIN FT QPEYKAANGKWEIIEFPEKYRQNTIHAALLRTGKVLMVAGSGNNQDNSDDKQYDTRIWD FT PVKGTIKKVPTPSDLFCTGHTQLANGNLLIAGGTKRYEKLKGDVTKAGGLMVVHNENPD FT KPITLPAGTKFTGKENGKTFVSKDPVLVPRAEKVFDPATGAFVRNDPGLGRIYVEAQKS FT GSAYETGTEDNYRIQGLSGADARNTYGIAQKLALDKKDFQGIRDAFEFDPVAEKYIKVD FT PMHEARWYPTLTTLGDGKILSVSGLDDIGQLVPGKNEVYDPKTKAWTYTDKVRQFPTYP FT ALFLMQNGKIFYSGANAGYGPDDVGRTPGIWDVETNKFTKVPGMSDADMLETANTVLLP FT PAQDEKYMVIGGGGVGESKLSSEKTRIADLKADAPKFVDGPSLEKGTRYPQASILPDDS FT VLVSGGSEDYRGRGDSNILQARLYHPDTNEFEQVADPLVGRNYHSGSILLPDGRLMFFG FT SDSLYADKANTKPGKFEQRIEIYTPPYLYRDSRPDLSGGPQTIARGGSGTFTSRAASTV FT KKVRLIRPSASTHVTDVDQRSIALDFTADGDKLTVTVPTGKNLVQSGWYMMFVTDGEGT FT PSKAEWVRVP" FT CDS complement(65052..66050) FT /transl_table=11 FT /gene="SCO2838" FT /gene_synonym="SCE20.12c" FT /product="putative secreted endoglucanase." FT /note="SCE20.12c, possible secreted endoglucanase, len: 332 FT aa. Similar to many including: Streptomyces halstedii FT SW:GUN1_STRHA(EMBL:Z12157) endoglucanase 1 precursor (EC FT 3.2.1.4) (321 aa), fasta scores opt: 613 z-score: 677.4 FT E(): 2.4e-30 37.6% identity in 343 aa overlap and FT Mycobacterium tuberculosis TR:O53607(EMBL:AL021428) FT putative cellulase (380 aa), fasta scores opt: 796 z-score: FT 876.5 E():0 44.3% identity in 298 aa overlap. Note that FT codon 10 maybe the true initiation codon. Contains a Pfam FT match to entry PF01341 Glyco_hydro_6, Glycosyl hydrolases FT and an appropriately positioned Prosite hit to PS00013 FT Prokaryotic membrane lipoprotein lipid attachment site. FT Also contains a possible N-terminal signal sequence." FT /db_xref="GOA:Q9RDB3" FT /db_xref="HSSP:1TML" FT /db_xref="InterPro:IPR016288" FT /db_xref="UniProtKB/TrEMBL:Q9RDB3" FT /protein_id="CAB65568.1" FT /translation="MSRRRAASAAALGAAALLLAGCSSSGDGDDKAAGAGITQQPKETG FT PFWVNPDGNAAQQVASLADAGKKDQAEEIRKIAQQPTGEWISPENPEEQARGFTEAADE FT AGRTALLVLYNIPHRDCGQYSEGGAADGDAYRSFVDGVAKGIGDRAATVVLEPDAVLHL FT VDGCTPQEFHEERYDLLKGAVAKLGALKNTKVYLDAGNAGWGHPDQIFDPLKRAGVDQA FT DGFAVNVSNFYTTEDSIAYGKQLSAKVGGKPFVIDTSRNGNGPYTEGAPDERWCNPPGR FT ALGETPTTKTADPLVDAYLWVKRPGESDGECKGGPKAGEWYPEYALKLAQG" FT misc_feature complement(65079..65906) FT /note="Pfam match to entry PF01341 Glyco_hydro_6, Glycosyl FT hydrolases family 6, score 273.60, E-value 2.5e-78" FT misc_feature complement(65985..66017) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(66159..66746) FT /transl_table=11 FT /gene="SCO2839" FT /gene_synonym="SCE20.13c" FT /product="putative lipoprotein." FT /note="SCE20.13c, possible lipoprotein, len: 190 aa. FT Contains an appropriately positioned Prosite hit to PS00013 FT Prokaryotic membrane lipoprotein lipid attachment site and FT a possible N-terminal signal sequence." FT /db_xref="UniProtKB/TrEMBL:Q9RDB2" FT /protein_id="CAB65569.1" FT /translation="MRTRGMVTVVAAVLALTAVSGCGDDEGGGGSTGAGGGGYGQSAGS FT GGRLMDTGTQGPVSAPTMADIEAFVSARTTCTDLHMEDRDSDHEDDPEAESAGKLWGIK FT ERAVCWDAKRMGVTLMSVDDMKSFQTQARRQSADWYLLGEDFAVTGGPATTADLRGSGL FT LALVCDPETQIPSGYTKEKGLVDGCTLTDFIS" FT misc_feature complement(66681..66713) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS 66863..67756 FT /transl_table=11 FT /gene="SCO2840" FT /gene_synonym="SCE20.14." FT /product="putative LysR-family transcriptional regulatory FT protein." FT /note="SCE20.14, possible LysR-family transcriptional FT regulatory protein, len: 297 aa. Similar to many other FT regulators including: Bacillus subtilis SW:ALSR_BACSU FT (EMBL:L04470;) als operon regulatory protein (302 aa). FT fasta scores opt: 373 z-score: 437.5 E(): 5.5e-17 26.6% FT identity in 286 aa overlap and Streptomyces lividans FT TR:Q9X9S5 (EMBL:Y18818) transcriptional regulator of LysR FT family (307 aa), fasta scores opt: 449 z-score: 525.1 E(): FT 7.3e-22 34.0% identity in 303 aa overlap. Contains a Pfam FT match to entry PF00126 HTH_1, Bacterial regulatory FT helix-turn-helix protein, lysR family with a putative FT helix-turn-helix motif situated between residues 17..38 FT (+4.47 SD)." FT /db_xref="GOA:Q9RDB1" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9RDB1" FT /protein_id="CAB65570.1" FT /translation="MVELRDIEIFLTLAEELHFGRTADRLHVSPARISQSIAKQERRIG FT APLFARSSRKVELTAIGAQLRRDLGAGYQRILDGTRAATAAARGSTGTLTLGLHGSQAH FT DHAHLLDLFRGRHPEVALRIQEVIFTDPFGPLRNGSVDVATAWLPVREPDLTVGPVVVT FT EPLLLMVATDHPLTRRDAVSMEDLADWPLPHSATPIPEYWQQTLVPTHTPGGRPTRRGP FT KVASFQELAAVVAAGGAISLVHGDAARYYQWRGLRYLRPYDAPTASWALIWPTAGETAL FT VRALATAARDTGPLTG" FT misc_feature 66893..67297 FT /note="Pfam match to entry PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix protein, lysR family, score FT 66.40, E-value 6.2e-16" FT CDS complement(67746..68486) FT /transl_table=11 FT /gene="SCO2841" FT /gene_synonym="SCE20.15c" FT /product="putative secreted protein" FT /note="SCE20.15c, possible secreted protein, len: 246 aa; FT similar to TR:Q9L2D9 (EMBL:AL137187) Streptomyces FT coelicolor putative secreted protein SC7A8.16c, 210 aa; FT fasta scores: opt: 493 Z-score: 488.6 E(): 1.4e-19; 40.580% FT identity in 207 aa overlap. Contains a possible membrane FT spanning hydrophobic domain" FT /db_xref="InterPro:IPR005754" FT /db_xref="UniProtKB/TrEMBL:Q9RDB0" FT /protein_id="CAB65571.1" FT /translation="MSEQDEQDTARKPTPESTPAPTPPPAAPGGRLVTGIAWVVLLLGL FT WLWGREATDVREGISRPATGDMAAAGRPPDVPLPPAHAPLDDARPQRLDVPGLDIDAPV FT VARGLDAEGAIEPPPFDQPGTVGWYAAGVTPGAAGTALMVGHVDTETRPAVFYQLSTLE FT PGQTIRVARDDDEVAEFTVDDVQVLTRDGFDAQQAYGPRDTGRSELRLITCGGTFDQTT FT DSYTANVVVSAYLTGTGADGHVTR" FT CDS complement(68489..69043) FT /transl_table=11 FT /gene="SCO2842" FT /gene_synonym="SCE20.16c" FT /product="putative membrane protein." FT /note="SCE20.16c, possible membrane protein,len: 184 aa. FT Contains possible membrane spanning hydrophobic domain and FT a possible N-terminal signal sequence." FT /db_xref="UniProtKB/TrEMBL:Q9RDA9" FT /protein_id="CAB65572.1" FT /translation="MGSLKVTLCAGAALVTAWCAPAAYTYAADGGAVSVSPSSPAPGTD FT VTLRVPDCTEKTAVAVSAAFESDVRLSLAAGDGVLVGSSQVRTSVRAGAYAVQVKCGEQ FT ARKGTITVRDERRPTAPASPVAPVDAGGGGTAELAASDAGDGARVDPPGTAHTVTGLVL FT AGIAAVAVALRSVRSRSRGTD" FT RBS complement(69049..69054) FT CDS complement(69147..69926) FT /transl_table=11 FT /gene="SCO2843" FT /gene_synonym="SCE20.17c" FT /gene_synonym="nagD" FT /product="putative N-acetylglucosamine-6-phosphate FT deacetylase" FT /note="SCE20.17c, nagD, probable FT N-acetylglucosamine-6-phosphate deacetylase, len: 259 aa. FT Highly similar to Escherichia coli FT SW:NAGD_ECOLI(EMBL:X14135) possible FT N-acetylglucosamine-6-phosphate deacetylase NagD (250 aa), FT fasta scores opt: 740 z-score: 847.6 E(): 0 43.0% identity FT in 249 aa overlap." FT /db_xref="GOA:Q9RDA8" FT /db_xref="InterPro:IPR006357" FT /db_xref="UniProtKB/TrEMBL:Q9RDA8" FT /protein_id="CAB65573.1" FT /translation="MADRKPIESWLTDMDGVLIHEGVPIPGADAFIKRLRDSGKPFLVL FT TNNSIYTPRDLHARLRRMGLEVPIESIWTSALATAQFLEDQRPGGSAYVIGEAGLTTAL FT HDIGYILTDHDPDYVVLGETRTYSFEAMTKAVRLINAGARFICTNPDETGPSTEGPLPA FT TGAVAALITKATGKQPYFAGKPNPLMMRTGLNAIGAHSETSAMIGDRMDTDVLAGMEAG FT MQTFLVLTGLTRPEQVENFPYRPSQVVDSIADLVERV" FT RBS complement(69935..69939) FT CDS complement(70002..70097) FT /transl_table=11 FT /gene="SCO2844" FT /gene_synonym="SCE20.18c" FT /product="hypothetical protein" FT /note="SCE20.18c, doubtful CDS, len: 31 aa." FT /db_xref="UniProtKB/TrEMBL:Q9RDA7" FT /protein_id="CAB65574.1" FT /translation="MDGVQVFEPDWNGIEENLTSSIGAWKEATGS" FT CDS complement(70097..70441) FT /transl_table=11 FT /gene="SCO2845" FT /gene_synonym="SCE20.19c" FT /product="putative GntR-family transcriptional regulatory FT protein." FT /note="SCE20.19c, possible GntR-family transcriptional FT regulatory protein, len: 114 aa. Weakly similar to FT Streptomyces coelicolor TR:CAB60175(EMBL:AL132824) putative FT transcriptional regulator (245 aa), fasta scores opt: 143 FT z-score: 180.9 E(): 0.011, 38.8% identity in 80 aa overlap FT and Bacillus subtilis TR:O34817(EMBL:AF017113) GntR family FT of transcriptional regulator YvoA (243 aa), fasta scores FT opt: 198 z-score: 245.5 E(): 2.7e-06. 38.1% identity in 97 FT aa overlap. Contains a Pfam match to entry PF00392 gntR, FT Bacterial regulatory proteins, gntR family with a putative FT helix-turn-helix motif situated between residues 25..46 FT (+4.27 SD)." FT /db_xref="GOA:Q9RDA6" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9RDA6" FT /protein_id="CAB65575.1" FT /translation="MPKQHAVKARIDRLVGELGEGSAIPTERDLSERHGVARETVRQAL FT RELLPEGRLRRRERGTVVAGPKPAQPLSLVGRTEGVRRQGRTPGRALVTLDRFHCCADA FT QDHHPRPSPS" FT misc_feature complement(70253..70423) FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 33.30, E-value FT 1e-08" FT CDS complement(70563..71783) FT /transl_table=11 FT /gene="SCO2846" FT /gene_synonym="SCE20.20c" FT /product="putative transcriptional regulatory protein" FT /note="SCE20.20c, possible transcriptional regulatory FT protein, len: 406 aa. Similar in parts to several proteins FT of the ROK (NagC/XylR) family including: Bacillus subtilis FT SW:GLK_BACSU (EMBL:D84432) glucokinase (EC 2.7.1.2) FT (glucose kinase) (321 aa), fasta scores opt: 320 z-score: FT 310.6 E(): 6.4e-10 34.1% identity in 164 aa overlap and FT Thermotoga maritima TR:Q9X1I0 (EMBL:AE001798) glucokinase FT (317 aa), fasta scores opt: 385 z-score: 370.1 E(): 3.1e-13 FT 33.6% identity in 360 aa overlap. Contains a Prosite hits FT to PS01125 ROK family signature and PS01228 Hypothetical FT cof family signature 1. Also contains a Pfam match to entry FT PF00480 ROK, ROK family and a putative helix-turn-helix FT motif situated between residues 45..66 (+5.25 SD)." FT /db_xref="InterPro:IPR000600" FT /db_xref="UniProtKB/TrEMBL:Q9RDA5" FT /protein_id="CAB65576.1" FT /translation="MNRTIGGGTGARTRTGEGGANLLALRSHNTALVLDLLRGAGAGGI FT SRLELAERTGLTPQAVSKITARLRGEGLAAEAGRRASTGGKPRTVLRLVPGAGHALGVH FT LDRDELRAVLVDLDGTVVAERRAPLDLGAGAETLLEGVARAAEELAAEGLAPAVPQDAG FT ARPPGGALAAAPTLLGLGAALPGPLDHVRGVLHRVTGFPEWDGYPLRDALERRLGVPVV FT VDKDTNAAALGLAVGGAGNEESGGGAGAGSFAYLHLGTGLGAGLVFGGGVHRGARTGAG FT EFGHQVVQLDGPPCTCGARGCIEALCLAAVARGDLAEAARVLGTGAANLAGLLDIDQVL FT LGGRTVAAAPEAFVQGVGAVLDARARREGGHDGAVPVRLAPGGPRGVAEGAAQLLLAPL FT FGRGDGG" FT misc_feature complement(70863..71255) FT /note="Pfam match to entry PF00480 ROK, ROK family, score FT 73.90, E-value 6.6e-21" FT misc_feature complement(70929..71012) FT /note="PS01125 ROK family signature" FT misc_feature complement(71415..71450) FT /note="PS01228 Hypothetical cof family signature 1" FT RBS complement(71795..71798) FT CDS 71840..72922 FT /transl_table=11 FT /gene="SCO2847" FT /gene_synonym="SCE20.21" FT /product="putative oxidoreductase." FT /note="SCE20.21, possible oxidoreductase, len: 360 aa. FT Similar to several other putative oxidoreductases e.g. FT Escherichia coli SW:YDGJ_ECOLI(EMBL:AE000258) hypothetical FT oxidoreductase (346 aa), fasta scores opt: 873 z-score: FT 972.9 E():0 45.0% identity in 353 aa overlap. Contains a FT Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase FT family." FT /db_xref="GOA:Q9RDA4" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RDA4" FT /protein_id="CAB65577.1" FT /translation="MTATPPGTPPLRVGLVGYGLAGSVFHAPLIAATEGLALDTVVTSN FT PERQQQARAEFPDVRTVATPDELFDRAAELDLVVVASPNKTHVPLATRALEAGLPVVVD FT KPVAGTAAEARALAALAEERGLLLSVFQNRRWDNDFLTLRQLLAEDALGEVWRFESRFE FT RWRPKPKGGWRESGDPSEIGGLLYDLGSHVVDQALVLFGPVTQVYAESVVRRAGAEADD FT DTFLALTHANGVRSHLYVSSTAAQLGPRFRVLGSKAGYVKHGLDPQEAALREGKRPGPG FT WGEEDESRWGRVGAGESPLTGGGQVAATVAGDYPAYYAAVAKALREGGPNPVDALAAAA FT ALDVLEAARRSARDGVVVSL" FT misc_feature 71870..72601 FT /note="Pfam match to entry PF01408 GFO_IDH_MocA, FT Oxidoreductase family, score 203.00, E-value 4.5e-57" FT CDS 72919..73395 FT /transl_table=11 FT /gene="SCO2848" FT /gene_synonym="SCE20.22" FT /product="conserved hypothetical protein" FT /note="SCE20.22, unknown, len: 158 aa. Similar to several FT proteins of undefined function e.g. Rhizobium meliloti FT SW:YPMI_RHIME(EMBL:M96584) hypothetical 18.2 KD protein FT (164 aa), fasta scores opt: 434 z-score: 540.5 E(): 1e-22 FT 49.7% identity in 143 aa overlap. Also similar to FT Saccharomyces cerevisiae SW:YBY7_YEAST(EMBL:X75891) FT hypothetical 20.5 KD protein (179 aa), fasta scores opt: FT 278 z-score: 350.5 E(): 3.8e-12 38.8% identity in 152 aa FT overlap" FT /db_xref="InterPro:IPR010371" FT /db_xref="UniProtKB/Swiss-Prot:Q9RDA3" FT /protein_id="CAB65578.1" FT /translation="MSTAPTAPTVAELEEQERRLVFRRFTNDDAWALGSLLVELARERE FT APVAIDIHRAGQQLFHAALPGSAPDNDAWIARKRRVVERYGSASYLVGSRFRAKGTTFE FT ESSRLDPDAYAAHGGSFPVTVAGVGVVGAVTVSGLPQVEDHRLVVEALERFIGE" FT CDS 73503..74375 FT /transl_table=11 FT /gene="SCO2849" FT /gene_synonym="SCE20.23" FT /product="conserved hypothetical protein SCE20.23." FT /note="SCE20.23, unknown, len: 290 aa. Similar to a protein FT of undefined function from Mycobacterium tuberculosis FT TR:O06328(EMBL:Z95390) hypothetical 30.7 KD protein (285 FT aa), fasta scores opt: 770 z-score: 928.4 E(): 0 48.6% FT identity in 247 aa overlap." FT /db_xref="InterPro:IPR019922" FT /db_xref="UniProtKB/TrEMBL:Q9RDA2" FT /protein_id="CAB65579.1" FT /translation="MNEATASLKESVGRYGVWSVQLRAEDPEGAAERAEAAAELERLGY FT GALWLGGNSAARHAAPLIRATERIVVGTSIQSIWEHKPSEAAAGFAELEVSHPGRFVLG FT LGVSHGPRVEGYRRPYSTMVGYLDELDRAGMRSGHRVLAALGPKMLDLSRDRAAGAIPY FT LVTPEHTAQARERLGEGPLLAPEFKVVLDADPSRARATARAYLAMYLKLPNYTKNFLNL FT GFTDDDVTGGGSDRLIDAVFAWGDEATIRARIDAFHAAGADHVALQLVTDDMARLPREG FT WRRLAALLA" FT CDS complement(74645..75502) FT /transl_table=11 FT /gene="SCO2850" FT /gene_synonym="SCE20.24c" FT /product="putative 2-hydroxyhepta-2,4-diene-1,7-dioate FT isomerase." FT /note="SCE20.24c, possible FT 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase, len: 285 aa. FT Similar to many including: Mycobacterium tuberculosis FT TR:O53242 (EMBL:AL021287) possible FT 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (239 aa), FT fasta scores opt: 544 z-score: 651.1 E(): 7e-29 40.3% FT identity in 221 aa overlap and similar in parts to the FT C-terminus of Escherichia coli SW:HPCE_ECOLI (EMBL:X75028) FT 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) FT (405 aa), fasta scores opt: 467 z-score: 556.6 E(): 1.3e-23 FT 40.2% identity in 214 aa overlap. Also similar to FT Streptomyces coelicolor TR:CAB55708 (EMBL:AL117387) FT putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase FT SCF41.05 (292 aa), fasta scores opt: 1142 z-score: 1213.4 FT E():0 61.5% identity in 286 aa overlap. Contains a Pfam FT match to entry PF01557 FAA_hydrolase, Fumarylacetoacetate FT (FAA) hydrolase family." FT /db_xref="GOA:Q9RDA1" FT /db_xref="HSSP:1GTT" FT /db_xref="InterPro:IPR002529" FT /db_xref="UniProtKB/TrEMBL:Q9RDA1" FT /protein_id="CAB65580.1" FT /translation="MKLLRVGTAGSERPALLDADGTLRDLSGVVTDIDGELLADEDALG FT RIRSAAEAGELPVLDGTGLRVGPPVGRIGKIVCIGLNYHDHARETGAEPPAEPVVFFKA FT PDTVVGPHDTVLVPRGSTKTDWEVELAVVIGRTARYLESAEEGLACVAGYAVAHDVSER FT EFQIERGGTWDKGKNCETFNPLGPWLVTADEVPDPQRLPLRLWVNGELKQDGTTAEQIF FT PVGEVVRYLSRFMVLRPGDIINTGTPAGVAMGQPEPKPYLRAGDVVELEIEGLGRQRQE FT LKEA" FT misc_feature complement(74735..75235) FT /note="Pfam match to entry PF01557 FAA_hydrolase, FT Fumarylacetoacetate (FAA) hydrolase family, score 229.90, FT E-value 3.6e-65" FT RBS complement(75512..75516) FT CDS complement(75670..76383) FT /transl_table=11 FT /gene="SCO2851" FT /gene_synonym="SCE20.25c" FT /product="putative membrane protein." FT /note="SCE20.25c, possible membrane protein, len: 237 aa. FT Similar in parts to many bacterial inner membrane proteins FT e.g. Streptomyces coelicolor TR:O54569(EMBL:Y16311) inner FT membrane protein, STH24.05 (431 aa), fasta scores opt: 240 FT z-score: 285.1 E(): 1.7e-08 25.0% identity in 232 aa FT overlap. Contains multiple possible membrane spanning FT hydrophobic domains." FT /db_xref="GOA:Q9RDA0" FT /db_xref="InterPro:IPR020001" FT /db_xref="UniProtKB/TrEMBL:Q9RDA0" FT /protein_id="CAB65581.1" FT /translation="MSVFASLVEHLADLLQPLFGASAAAAAIILFTALVRLLVHPLSRA FT AARGQKARTRLQPRIAELRRKHAKNPEKLQRAVLELHAEEKVSPLSGCLPSLCQIPAFF FT LLYHLFSSSTIGGEVNGLLSHQLLAAPLGGRWADAFGDGGLLGGAGLVYVALFAVVAGV FT ATFSYRLTRRTMADRPVLPAGDAGAVPGVGALTRVMPFMSFFTLVTVAVVPLAAALYVV FT TSTTWSAVERAVLYR" FT RBS complement(76396..76400) FT CDS complement(76497..76832) FT /transl_table=11 FT /gene="SCO2852" FT /gene_synonym="SCE20.26c" FT /product="putative membrane protein." FT /note="SCE20.26c, possible membrane protein, len: 111 aa. FT Contains a possible N-terminal membrane spanning FT hydrophobic domain." FT /db_xref="UniProtKB/TrEMBL:Q9RD99" FT /protein_id="CAB65582.1" FT /translation="MYERGEQPMTRERSVPRPLLVLLLVLLPVALVDVGSLSATVALAA FT TAAVGSALAVCAVIAARCAPAVPRTRVRTAIRDRDLRTAFLPQRDPDAPGRRRPRAPGH FT ALPATAA" FT CDS complement(76890..77444) FT /transl_table=11 FT /gene="SCO2853" FT /gene_synonym="SCE20.27c" FT /product="conserved hypothetical protein" FT /note="SCE20.27c, unknown, len: 184 aa. Similar to many FT proteins of unknown function including: Mycobacterium FT tuberculosis SW:YU95_MYCTU(EMBL:Z95150) hypothetical 17.8 FT KD protein (158 aa), fasta scores opt: 396 z-score: 478.9 FT E(): 2.7e-19 42.6% identity in 141 aa overlap and FT Streptomyces coelicolor TR:O86588(EMBL:AL031514) FT hypothetical 23.3 KD protein SC2H4.05 (216 aa), fasta FT scores opt: 294 z-score: 357.1 E(): 1.7e-12 44.6% identity FT in 112 aa overlap. Contains a Pfam match to entry PF01638 FT DUF24, Protein of unknown function" FT /db_xref="InterPro:IPR002577" FT /db_xref="UniProtKB/TrEMBL:Q9RD98" FT /protein_id="CAB65583.1" FT /translation="MATVDGMALGKDYATQECSIARALEVVGERWTLLVIRDALYGVRR FT YNDFLVHLGIPRAVLANRLQALTAEGILEKRRYQESPTRDEYVLTERGIALWPALRALG FT IWGREQLGGEPMRTFWHADCGTELSPHGTCATCGTLVAVRDIDMRPGPGLAADPADPVS FT RALLGPRRLLQPIETEQRGPA" FT misc_feature complement(77100..77369) FT /note="Pfam match to entry PF01638 DUF24, Protein of FT unknown function, score 78.50, E-value 1.4e-19" FT RBS complement(77451..77455) FT CDS 77548..78981 FT /transl_table=11 FT /gene="SCO2854" FT /gene_synonym="SCE20.28" FT /product="putative transmembrane efflux protein." FT /note="SCE20.28, possible transmembrane efflux protein, FT len: 477 aa. Similar to many including: Mycobacterium FT smegmatis TR:Q50392(EMBL:U40487) proton antiporter efflux FT pump (504 aa), fasta scores opt: 626 z-score: 586.9 E(): FT 2.6e-25 32.1% identity in 471 aa overlap and Streptomyces FT coelicolor TR:Q9ZBW5(EMBL:AL034443) putative integral FT membrane efflux protein SC4B5.03C (504 aa), fasta scores FT opt: 729 z-score: 681.9 E(): 1.3e-30 36.6% identity in 435 FT aa overlap. Contains a Prosite hit to PS00216 Sugar FT transport proteins signature 1 and multiple possible FT membrane spanning hydrophobic domains." FT /db_xref="GOA:Q9RD97" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9RD97" FT /protein_id="CAB65584.1" FT /translation="MTETGTDSPTTPTAPPTGTPATTAAAAPPPDRALPPPHPGRTLAL FT TSAATAVALMAFTAPMVTLPETAADLHTSLSAQAWLLNGTPLGLAALLLVAGSLADDYG FT RRRLFVSGTLALGVTTVLGAFASTTWLFTLARVAQGAASAALLASSLGLLVHAFPTPAG FT RLRATGVWGAFVSGGIAVGPVLVGAIPDWRVAHGVLGAAALVVAGLGARALSESRSPRE FT GRPDFAGALTFGPALVALVAALTLGRDGWLRAPVGLLLAAAVLLGALFVVLERRAATPM FT IDLSLLRRPLFLASSAGGLFTGLSVIGLFSFLPTVLQRALGLSPLDTALLSLLWAGLAF FT AVALQVRRIAHRVSPRHQLVVGFALHAVGVLTMLGAVGAGSWARLLPGLVVAGVGSGLL FT NAALPLLAVESVPAARAAMGSGAQQTFRYIGSCAGVALTIAIATSAGSPGAGTDVALWV FT SAGLAVAAGVLVATLRERH" FT misc_feature 77833..77886 FT /note="PS00216 Sugar transport proteins signature 1" FT CDS 79193..80209 FT /transl_table=11 FT /gene="SCO2855" FT /gene_synonym="SCE20.29" FT /product="hypothetical protein SCE20.29." FT /note="SCE20.29, unknown, len: 338 aa." FT /db_xref="UniProtKB/TrEMBL:Q9RD96" FT /protein_id="CAB65585.1" FT /translation="MRPDTPAENVDHAAEAARLERTAGLYPEDAEALLLRAAAHLELSG FT DRPAATKLYDRLLSSETSVPLDNPSLVRALKASNLWEYDHEAEARAIIDGVRAASPRDP FT APWVIAAEALESHDELEAAHETFTEGARLLLTDVPEPPYSTHPLLYGRHRVRRMLGLAH FT DAWDTLADTLHSMPVSLDELHDPKRLWSLGSDNPADLEAEILRLRAELGAYREALSRPF FT PVAMLHWPAAELTELIEAYPALASEYPSYEEHLASIEAALRELASSGTPNLGVVPGTVP FT SYEAFAASEGASPADPVLLPQYATTLAARGLAVAWPPQRGADCWCGSGRAYGECHGR" FT RBS 80300..80304 FT CDS 80315..80773 FT /transl_table=11 FT /gene="SCO2856" FT /gene_synonym="SCE20.30" FT /product="hypothetical protein SCE20.30." FT /note="SCE20.30, unknown, len: 152 aa. Similar to another FT protein of unknown function from Streptomyces coelicolor FT TR:O86819(EMBL:AL031031) SC7C7.14 (161 aa), fasta scores FT opt: 152 z-score: 189.7 E(): 0.0035 31.7% identity in 123 FT aa overlap." FT /db_xref="GOA:Q9RD95" FT /db_xref="InterPro:IPR013538" FT /db_xref="UniProtKB/TrEMBL:Q9RD95" FT /protein_id="CAB65586.1" FT /translation="MSTDQTPTAAGSGFSYTLTRTLDAPAARVWQAWTTPDQYAQWAYA FT VPGSVEMDVRPGGTWKATMRTPDGTEFPLTGSYIEVAEHRALTIGMNVPGRPDPATMTV FT ELAEEGPRNTVITLRQTCDTAEERDGAEQGSGMLLDGLTGFLAGGKQG" FT CDS complement(80894..81238) FT /transl_table=11 FT /gene="SCO2857" FT /gene_synonym="SCE20.31c" FT /product="putative membrane protein." FT /note="SCE20.31c, possible membrane protein, len: 114 aa. FT Contains possible membrane spanning hydrophobic domains and FT an N-terminal signal sequence." FT /db_xref="UniProtKB/TrEMBL:Q9RD94" FT /protein_id="CAB65587.1" FT /translation="MSVRRGRVHPLVPLLMLSVPYLFTTLLPDVPGLALCSGLIRIAGG FT VLLCTSVHWTPVRKIVGVVLSVVAPAVAGIVWRETTVAPAGDTPALVANLVVLAVVAGT FT SAWLWRSRRG" FT CDS complement(81253..81510) FT /transl_table=11 FT /gene="SCO2858" FT /gene_synonym="SCE20.32c" FT /product="hypothetical protein SCE20.32c." FT /note="SCE20.32c, unknown, len: 85 aa." FT /db_xref="UniProtKB/TrEMBL:Q9RD93" FT /protein_id="CAB65588.1" FT /translation="MKTPTAPTTPADPVRDYLAAVEREASALPADRRQELLADLAEHID FT VTRAERPDVATGEILAGLGTPVRSRRRRCPRRAVVVPGQR" FT CDS complement(81507..81884) FT /transl_table=11 FT /gene="SCO2859" FT /gene_synonym="SCE20.33c" FT /product="conserved hypothetical protein SCE20.33c." FT /note="SCE20.33c, unknown, len: 125 aa. Similar several FT other proteins of unknown function e.g. from Lactococcus FT lactis TR:O87247(EMBL:AE001272) conserved hypothetical FT protein (114 aa), fasta scores opt: 226 z-score: 311.1 E(): FT 6e-10 35.1% identity in 94 aa overlap." FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9RD92" FT /protein_id="CAB65589.1" FT /translation="MEPGDPTKQARAAAQLRKGVLEYCVLALMRDRPRYGVELLHALEE FT SGALATSQGTVYPLLSRLRREDLVTTTWQESASGPPRRYYALTATGRAALDEFTHVWPG FT FRDAVDAFLATTPHPSAGDLA" FT repeat_region 81932..82038 FT /note="repeat region containing 2x GGGGGCCC and 9xCCCGGCGG FT repeated sequences." FT CDS complement(82071..82481) FT /transl_table=11 FT /gene="SCO2860" FT /gene_synonym="arr" FT /product="rifampin ADP-ribosyl transferase" FT /note="SCE20.34c, arr, rifampin ADP-ribosyl transferase, FT len 136 aa. Highly similar to Mycobacterium smegmatis FT TR:O67972 (EMBL:AF001493) rifampin ADP-ribosyl transferase FT (143 aa), fasta scores opt: 487 z-score: 611.8 E(): 1.1e-26 FT 53.0% identity in 134 aa overlap and Pseudomonas aeruginosa FT TR:O87490 (EMBL:AF078527) ribosylating transferase ARR-2 FT (150 aa), fasta scores opt: 429 z-score: 540.3 E(): 1e-22 FT 50.0% identity in 128 aa overlap" FT /db_xref="GOA:Q9RD91" FT /db_xref="UniProtKB/TrEMBL:Q9RD91" FT /protein_id="CAB65590.1" FT /translation="MDEVLDEGPFFHGTKADLRVGDHLTAGFPSNYRPEILMNHIYFTA FT LRDGAGLAAELAAGDGEPRVYAVEPTGEFENDPNVTDKKFPGNPTRSYRSTEPLRVVGE FT VVDWTRQTPEALRTWRERLDAMRLEGRAEIIN" FT CDS 82709..83431 FT /transl_table=11 FT /gene="SCO2861" FT /gene_synonym="SCE20.35." FT /product="hypothetical protein SCE20.35." FT /note="SCE20.35, unknown, len: 240 aa." FT /db_xref="UniProtKB/TrEMBL:Q9RD90" FT /protein_id="CAB65591.1" FT /translation="MNSCPSRPRGDTLHQHERMDRESTGGTPTRLPRPSAPAGPAGDLP FT RGAAGPLGPSAVTVLQRAAGNAATTRAVAAGPGRRPPGADLTVQRAENDDAGGGASGGT FT AEAKSIAEGEVKSVGPGGTITYPSVTSCLAITVYLRDGGKVGGHASLFKASGGMYSDQI FT LPEIKARVGKSRVERIDVSGAISSWNPAYLKTAIENSNPAPEQKNDPDGIRNVVSGILG FT RQAKKVSVQETRDGTLTR" FT CDS complement(83528..83761) FT /transl_table=11 FT /gene="SCO2862" FT /gene_synonym="SCE20.36c" FT /product="hypothetical protein SCE20.36c." FT /note="SCE20.36c, unknown, len: 77 aa." FT /db_xref="UniProtKB/TrEMBL:Q9RD89" FT /protein_id="CAB65592.1" FT /translation="MPGQHMGRRFCTDLGVDGLPTGGLETLQVTAHAIRDQLLVNPCDR FT LIRTPRLLHPVPLHHRVDVEAVVAGVTDTRMG" FT RBS 83897..83900 FT CDS 83912..86749 FT /transl_table=11 FT /gene="SCO2863" FT /gene_synonym="SCE20.37" FT /product="putative helicase" FT /note="SCE20.37, possible helicase, len: 945 aa. Weakly FT similar to Saccharomyces cerevisiae (Baker's yeast) FT TR:Q06683(EMBL:U32517) DEAD box family helicase family FT protein (689 aa), fasta scores opt: 455 z-score: 511.5 E(): FT 4.1e-21 27.2% identity in 357 aa overlap. Also weakly FT similar to several bacteriophage proteins including: FT Lactococcus bacteriophage (isolate 7-9) SW:V51K_BPL79 FT (EMBL:M36388) 51.5 KD protein which may play a role in FT either regulating bacteriophage replication or FT bacteriophage specific genes (452 aa), fasta scores opt: FT 407 z-score: 460.0 E(): 3.1e-18 27.4% identity in 328 aa FT overlap. Contains Prosite hit to 2xPS00017 ATP/GTP-binding FT site motif A (P-loop) and a Pfam match to entry PF00271 FT helicase_C, Helicases conserved C-terminal domain." FT /db_xref="GOA:Q9RD88" FT /db_xref="InterPro:IPR014001" FT /db_xref="UniProtKB/TrEMBL:Q9RD88" FT /protein_id="CAB65593.1" FT /translation="MLALAEQEAPGAYAVRPLTPLSETSLLTNSPEDLNLGSELRAELA FT TADRIDLLCAFVKWYGIRVLEDALLAAKARGVPIRIITTTYMGATDRRALDRFVREFGA FT TVKVNYETRSTRLHAKAWLFRRGTGFDTAYVGSSNLSRAALLDGLEWNVRLSSVATPAV FT MDKFEATFDAYWNDVAFETYDPDVDGEHLDAALAQAGGTASTTDFKINLSGLQVHPFPH FT QRDMLERLSAEREIRGRHRNLLVAATGTGKTVMAALDYRALSNQATSGRPRLLFVAHRK FT EILKQSLRTYREVLDDASFGELLYGGADPHEWSHVFASVQSLNVQRLEQLAPDHFDVIV FT IDEFHHATAGTYRRVIEHFTPKELLGLTATPERMDGLNVQDEFFDGRIAAEMRLWEALE FT NDLLSPFHYFGIPDGTDLTNLTWQKGSYADQELGNLLTANDARARIIVKQVRDKISDPG FT AMRALGFCVTKAHAHFMADYFRRAGFQAAALDSDSSSEVRAQALRDLQDGKLQVIFSVD FT LFNEGLDIPDVDTLLLLRPTNSATVFLQQLGRGLRRTDTKPVLTVLDFIGQHRAEFRFE FT EQFRAMTNLSRNRLVEHIERGFPQLPSGCQIILEGKAKSLVLDNIRTQLAATVKTLVKE FT VKEYSTPLLADYLRESRREIKELYKNGNSWTVVLRRAGLAEEPAPPGEEALLKRVHAFL FT HVDDPERAQAYLSLLADDAPSYEELDQTGQAYARMLFFNLWDNAGGYTSYAQGLAALRP FT QRALRDELRQVLSYVIDRADHVPIPLSDGLGTVPLKVHSSYNRSEILAALGIARFGGQM FT PRSFAQGVQWAEETQTDALLITLEKDEKDFSPTVRYKDYAISPNLFHWESQNATSPDSA FT TGKRYQQHAGRGSHVLLFMRRYATTDTGKSQPWMLLGPATYVRHTGSKPMAITWHLDHD FT LPADVWTYSAAIQAS" FT misc_feature 84647..84670 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 85328..85573 FT /note="Pfam match to entry PF00271 helicase_C, Helicases FT conserved C-terminal domain, score 63.30, E-value 5.3e-15" FT misc_feature 86591..86614 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(<86894..>87442) FT /transl_table=11 FT /gene="SCO2864" FT /gene_synonym="SCE6.01c" FT /product="hypothetical protein SCE6.01c (fragment)." FT /note="SCE6.01c, unknown, partial CDS, len: > 183 aa. FT Similar to several proteins of undefined function e.g. FT Streptomyces coelicolor TR:Q9XD95(EMBL:AF106004) FT hypothetical 15.4 KD protein found within the whiJ FT sporulation regulatory locus (141 aa), fasta scores opt: FT 232 z-score: 304.9 E(): 1.5e-09 37.4% identity in 131 aa FT overlap and Streptomyces coelicolor FT TR:Q9ZBT2(EMBL:AL034446) putative regulatory protein, FT SC1A9.20 (135 aa), fasta scores opt: 201 z-score: 266.1 FT E(): 2.2e-07 38.3% identity in 120 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q8CJY3" FT /protein_id="CAD55456.1" FT /translation="MDDSRWRPTQPWKLPFLAEADQVRALRRALRIHLEYWGLHELTDA FT AELCASELVANVIKHVGPETPSTLVASLGVARLRIEVHDPDARALPTLACASLDAEVGR FT GMALVDAMSDRWGVVLAGDHKVTWCEFRIDVARTERRHVLMPRLARAADVLSLYSVSGA FT MQQPLEQGRLSAVLAEEAAI" FT RBS 87628..87632 FT CDS 87641..88483 FT /transl_table=11 FT /gene="SCO2865" FT /gene_synonym="SCE6.02" FT /product="putative regulatory protein." FT /note="SCE6.02, possible regulatory protein, len: 280 aa. FT Similar to several proteins of undefined function FT including: Streptomyces albulus TR:BAA89264 (EMBL:AB025200) FT hypothetical protein ORF312 (285 aa), fasta scores opt: 585 FT z-score: 728.2 E():0 38.2% identity in 280 aa overlap and FT Streptomyces coelicolor TR:Q9Z543 (EMBL:AL035212) putative FT DNA binding protein, SC9B2.16C (303 aa), fasta scores opt: FT 313 z-score: 391.9 E(): 2.1e-14 31.0% identity in 284 aa FT overlap. Also weakly similar to SCE6.06, also located on FT this cosmid, fasta scores opt: 269 z-score: 293.0 E(): FT 8.1e-11 27.5% identity in 265 aa overlap. Contains a Pfam FT match to entry PF01381 HTH_3, Helix-turn-helix with the FT putative helix-turn-helix motif situated between residues FT 25..46 (+5.35 SD)." FT /db_xref="GOA:Q9KZT6" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q9KZT6" FT /protein_id="CAB88806.1" FT /translation="MAAGPTTRRRQLGADLRRLRERKGLTLEEAGSRVGISKATLSRYE FT TKEGTVKWPAVDALCREYAATDEERMALVELAKGAKIQGWWRSLADPIPDSMNLMLTLE FT DEVVREDHYACMYIPGLLQTRAYAEAVHRASEVQCDEREVQHMVDIRMRRQELLERDEP FT PRIWCVIDEAAIRRRVGGHDVMREQLTHLLACAERPHITIQVLPFSLGAHAAAVGSFVT FT LRGQARELDVVYVDLLGGGLFMEKPEELERYRLAFDYLSAQALDLESSVELIDQVSKE" FT misc_feature 87686..87850 FT /note="Pfam match to entry PF01381 HTH_3, Helix-turn-helix, FT score 26.10, E-value 0.00082" FT CDS 88773..89027 FT /transl_table=11 FT /gene="SCO2866" FT /gene_synonym="SCE6.03" FT /product="hypothetical protein SCE6.03." FT /note="SCE6.03, unknown, len: 84 aa." FT /db_xref="UniProtKB/TrEMBL:Q9KZT5" FT /protein_id="CAB88807.1" FT /translation="MRTIGGVRAALLADLGFPGDKENFESDVQRALEVSPEADHTAVVT FT VIVDYRGRIRLCQDPDFEAAVQEGIDLTIRLKREARGGE" FT RBS 89219..89223 FT CDS 89229..89456 FT /transl_table=11 FT /gene="SCO2867" FT /gene_synonym="SCE6.04" FT /product="hypothetical protein SCE6.04" FT /note="SCE6.04, unknown, len: 75 aa. Similar to another FT hypothetical protein from Streptomyces coelicolor FT TR:CAB53305 (EMBL:AL109973) SCJ30.10C (92 aa), fasta scores FT opt: 101 z-score: 154.5 E(): 0.35 32.1% identity in 81 aa FT overlap." FT /db_xref="UniProtKB/TrEMBL:Q9KZT4" FT /protein_id="CAB88808.1" FT /translation="MALHRLGKDPESPNNGSPTVYLDDETGNYILQGWRVTDARRLAQL FT DVPGHETVIEFPRRMMQFFPEVSGGAAADV" FT RBS 89456..89460 FT CDS 89464..89943 FT /transl_table=11 FT /gene="SCO2868" FT /gene_synonym="SCE6.05" FT /product="conserved hypothetical protein" FT /note="SCE6.05, hypothetical protein, len: 159 aa. The FT C-terminus shares 54.1% identity in 74 aa overlap with FT Streptomyces coelicolor TR:CAB53304(EMBL:AL109973) FT hypothetical 10.9 KD protein, SCJ30.09C (96 aa); similar FT also to the SCP1 plasmid borne TR:Q9ACW6 (EMBL:AL590464) FT Streptomyces coelicolor conserved hypothetical protein FT SCP1.185, 184 aa; fasta scores: opt: 520 Z-score: 652.0 FT E(): 1.1e-28; 49.390% identity in 164 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9KZT3" FT /protein_id="CAB88809.1" FT /translation="MRSAQRSAHHLEMRDAYDLDADYREWSEGNLFDPSERWPWWIELV FT SSTVARGVAVQRARIVSEPLSSYTRYEYELTGGHNVKAGEDVRWLPRRQSSDLALPGND FT FWLFDGVTVLFNHFAGDGTMTGEELVTDQSVVGLCSSAFSAVWERAIPHQEYRPA" FT CDS 89967..90812 FT /transl_table=11 FT /gene="SCO2869" FT /gene_synonym="SCE6.06" FT /product="putative regulatory protein." FT /note="SCE6.06, possible regulatory protein, len: 281 aa. FT Similar to several proteins of undefined function e.g. FT Streptomyces albulus TR:BAA89264(EMBL: AB025200) plasmid FT pNO33 protein ORF312 (285 aa), fasta scores opt: 356 FT z-score: 441.0 E(): 3.9e-17 30.9% identity in 282 aa FT overlap. Also weakly similar to SCE6.02, also located on FT this cosmid, fasta scores opt: 269 z-score: 293.0 E(): FT 8.1e-11 27.5% identity in 265 aa overlap. Contains a FT putative helix-turn-helix motif situated between residues FT 27..48 (+4.07 SD)." FT /db_xref="GOA:Q9KZT2" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q9KZT2" FT /protein_id="CAB88810.1" FT /translation="MSSSSSIQQARETLGKRLREIRKDAGLTARELASRAGWHESKCSR FT IENGRTPPSDDDLRVYTLHCAAADQTADLIATARNIEGAYVEWRRMERSGLRRAQESVI FT PLWERTRHFRGYSSWLIPGPFQTPAYIRALLTSIRDRRSLPDDLEAAVDVRVDKQRVLY FT EGARRFAVVLEESTLRHLIGGPETMAGQLGHLLSLATLPNVSLGVIPLSTDRTALWPVE FT DFWVFDDSQVNVELVSAFLTITQPHEVNTYARTFAALADSAVYGAPARTLITSAIDSLG FT " FT CDS 90884..91180 FT /transl_table=11 FT /gene="SCO2870" FT /gene_synonym="SCE6.07" FT /product="hypothetical protein SCE6.07." FT /note="SCE6.07, unknown, len: 98 aa." FT /db_xref="UniProtKB/TrEMBL:Q9KZT1" FT /protein_id="CAB88811.1" FT /translation="MESMVKERVFSPAASTQAPWAMRLVTDRLAVSPAPYTSVTLDPAT FT QTARYTDAVGRVVEMGKHGTSRTSGTASVSGGGDGQQPQPQSQDDTTTDYESD" FT CDS 91184..92164 FT /transl_table=11 FT /gene="SCO2871" FT /gene_synonym="SCE6.08" FT /product="conserved hypothetical protein SCE6.08" FT /note="SCE6.08, unknown, len: 326 aa. Similar to FT Streptomyces coelicolor TR:CAB69667(EMBL:AL137165) FT hypothetical 34.9 kd protein, SCF42.05 (328 aa), fasta FT scores opt: 371 z-score: 450.8 E(): 1.1e-17 35.6% identity FT in 334 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9KZT0" FT /protein_id="CAB88812.1" FT /translation="MARTVLVVTALEDVTADWVIAALNERGVTVVRVDPADVGPRLSFG FT FRIGADAPAWSGLLRTESRDVELGEVGAVYHRRPTPYRDRFARLPRQQRDFAAAEARHG FT LGGVLNDLRSAVYVNHPAAVARAEFKPGQLRRFAELGLRIPATLVTNGLVAARDFAARH FT PSVVCKTFRGLPPGEDGRAGAIWTQRVHSDDFDDSLSVTAHLFQAEVPKAGDVRVTVVG FT RRVFAQRISAPCGALDWRCGSWDDLVHSPVTVPSVVETALHRYLADSGLVFGCFDFALT FT GDGSSPDDWWAIECNPNGQWGWLPDAFAITEAFADILSTEGSGSS" FT CDS 92161..93393 FT /transl_table=11 FT /gene="SCO2872" FT /gene_synonym="SCE6.09" FT /product="hypothetical protein SCE6.09." FT /note="SCE6.09, unknown, len: 410 aa. Weakly similar to FT several methyltransferase e.g. Streptomyces coelicolor FT TR:CAB71208(EMBL:AL138538) putative O-methyltransferase, FT SC6D10.13C (324 aa), fasta scores opt: 337 z-score: 387.6 FT E(): 3.7e-14 37.2% identity in 277 aa overlap." FT /db_xref="GOA:Q9KZS9" FT /db_xref="InterPro:IPR000682" FT /db_xref="UniProtKB/TrEMBL:Q9KZS9" FT /protein_id="CAB88813.1" FT /translation="MTLPPDLDTDAGALRAAMVKGLAGATADADADARCPVHPAWLAAA FT EKVPRHAFVPGFYLPADEPDAQGLTVWEPVTAKLDYGRWLAAAYSDATLITQFDGEKTD FT WERPAVRHGGAPTSSSTLPSLVLRMWSDADVVEGHTVLEVGTGTGYSTALACERLGSSH FT VSSVEVDAVRLEGAADALYGCGYTPVLARADGLYGYWPEAWFDRIVAACSFRSVPPALL FT SQTRPGGKVLLPLSGWLYGNARVLLTAAGDGTAEGPLLPGTISFMPARAHAAPAYGNPS FT DWAAGLHEEPPRSARHAPERLTAATEEAFHLRFLAQGAVPDAQLVTVDGAPHLIDVVSG FT SVATLTPDSGAWSVREGGPLKLWSRIEGLIDAFDAAGRPGPETFTLRVDDDGQRLLHAR FT LPQLRLPQPVR" FT CDS complement(93444..93989) FT /transl_table=11 FT /gene="SCO2873" FT /gene_synonym="SCE6.10c" FT /product="hypothetical protein SCE6.10c." FT /note="SCE6.10c, unknown, len: 181 aa. Shows weak FT similarity to Streptomyces coelicolor TR:CAB51981 FT (EMBL:AL109663) hypothetical protein, SC4A10.05C (160 aa), FT fasta scores opt: 171 z-score: 221.2 E(): 6.9e-05 32.7% FT identity in 156 aa overlap." FT /db_xref="GOA:Q9KZS8" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9KZS8" FT /protein_id="CAB88814.1" FT /translation="MSPPLRGRMLRGMTSEDHSPCATVTTRVSVRDLLPQDLPACTWSG FT SATHLRHVERELTRAAAGEVDYLAVCTPVDLPVAIGGIDYQVSEEAGTIGQLAVLPALQ FT SCGLGTLLVRAAEDRIRDRGLRSAELAVEEDNPRARALYERLGYVAYGREPDAWDEEGP FT DGSIRRHETMCIRMRRSL" FT CDS complement(94169..95140) FT /transl_table=11 FT /gene="SCO2874" FT /gene_synonym="SCE6.11c" FT /product="putative oxidoreductase" FT /note="SCE6.11c, possible oxidoreductase, len: 323 aa. FT Similar to several other members of the short-chain FT dehydrogenases/reductases family including: Streptomyces FT antibioticus SW:OXIR_STRAT(EMBL:M96551) probable FT oxidoreductase (298 aa), fasta scores opt: 641 z-score: FT 722.8 E(): 7.9e-33 43.4% identity in 304 aa overlap and FT Streptomyces coelicolor TR:AAF26372(EMBL:AF204735) putative FT NADP-dependent oxidoreductase (297 aa), fasta scores opt: FT 670 z-score: 755.1 E(): 0 43.9% identity in 289 aa overlap. FT Contains a Pfam match to entry PF00106 adh_short, short FT chain dehydrogenase." FT /db_xref="GOA:Q9KZS7" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9KZS7" FT /protein_id="CAB88815.1" FT /translation="MTHTEQQPLNSPFSAATTAEDVMAGHDLSGVTAVVTGGYSGLGLA FT STRALTAAGARVLVPARRPDIARAALRDVKGSEVVPMDLTDLDGVRSAAAHIGDRIDRI FT DLLMAAAGVMATPERRVGPGWEFQLAANHFGHFTLACELYPLLAAAGGARVVAYSSAGH FT AMTDIRRHDPHFRTGYDRWLAYGQAKTANALFAVHLDALGKDDGIRAFALHPGKIITGL FT QREMPLQEQIDAGWVDEHGNVVAADFKTASQGAATGLWAATSPLLDGRGGLYLADCDVA FT RVFPPDTPMDDNGVRPYAVEPANAARLWEMSLAATGATPPTR" FT misc_feature complement(94478..95050) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 50.10, E-value 4.8e-11" FT CDS 95220..95627 FT /transl_table=11 FT /gene="SCO2875" FT /gene_synonym="SCE6.12" FT /product="putative MerR-family transcriptional regulator." FT /note="SCE6.12, possible MerR-family transcriptional FT regulator, len: 135 aa. Similar to many regulators e.g. FT Haemophilus influenzae SW:Y186_HAEIN(EMBL:U32704) FT hypothetical transcriptional regulator (135 aa), fasta FT scores opt: 233 z-score: 315.6 E(): 3.8e-10 33.9% identity FT in 121 aa overlap. Also similar to Streptomyces coelicolor FT TR:CAB62710(EMBL:AL133423) putative MerR-family FT transcriptional regulator, SC4A7.06C (196 aa), fasta scores FT opt: 295 z-score: 393.5 E(): 1.7e-14 41.2% identity in 119 FT aa overlap. Contains a Prosite hit to PS00552 Bacterial FT regulatory proteins, merR family signature and a Pfam match FT to entry PF00376 merR, Bacterial regulatory proteins, merR FT family with a putative helix-turn-helix motif situated FT between residues 6..27 (+4.68 SD)." FT /db_xref="GOA:Q9KZS6" FT /db_xref="HSSP:1Q06" FT /db_xref="InterPro:IPR000551" FT /db_xref="UniProtKB/TrEMBL:Q9KZS6" FT /protein_id="CAB88816.1" FT /translation="MSGQSLSIGEVAERTGLSVHALRFYEREGLLVGPVRRTSGGRRRY FT SSFDVDWLLICVKLRESGMPLADLKQFAALVRQGPGNEAERLRLLDTHQRRVDAQIEAL FT EECRTVIAWKVGVYAEHLARGEAGGLWDPTA" FT misc_feature 95244..95312 FT /note="PS00552 Bacterial regulatory proteins, merR family FT signature" FT misc_feature 95244..95354 FT /note="Pfam match to entry PF00376 merR, Bacterial FT regulatory proteins, merR family, score 56.50, E-value FT 5.9e-13" FT CDS 95655..96281 FT /transl_table=11 FT /gene="SCO2876" FT /gene_synonym="SCE6.13" FT /product="putative acetyltransferase." FT /note="SCE6.13, possible acetyltransferase, len: 208 aa. FT Similar to several including: Escherichia coli FT SW:ATDA_ECOLI(EMBL:D25276) spermidine N1-acetyltransferase FT (EC 2.3.1.57) (185 aa), fasta scores opt: 208 z-score: FT 273.6 E(): 8.2e-08 25.3% identity in 158 aa overlap and FT Streptomyces coelicolor TR:CAB76075(EMBL:AL157953) putative FT acetyltransferase, SCL11.12C (232 aa), fasta scores opt: FT 287 z-score: 372.5 E(): 2.6e-13 33.7% identity in 187 aa FT overlap. Contains a Pfam match to entry PF00583 FT Acetyltransf, Acetyltransferase (GNAT) family." FT /db_xref="GOA:Q9KZS5" FT /db_xref="HSSP:1NSL" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9KZS5" FT /protein_id="CAB88817.1" FT /translation="MAPSPDIRCRSRPVGRRMTAMTLATPTLDTDRLRLRPFTEDDAGF FT LYAMHSSRHVMRYWDSPPWTERARAGRFVGMCRKMADEGTGVRVAVDRASDGAFVGWCC FT LAEWNPVYRSASLGYCLDEAMWGHGYATEAAHALLRWAFDTLDLNRVQAEADTRNAASA FT RVLEKVGFVREGTLREDCVVDGEVSDSWVYGLIRRDWRPSAAPVR" FT misc_feature 95757..96170 FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 23.40, E-value FT 0.0052" FT CDS 96375..96761 FT /transl_table=11 FT /gene="SCO2877" FT /gene_synonym="SCE6.14" FT /product="putative membrane protein." FT /note="SCE6.14, possible membrane protein, len: 128 aa. FT Contains an N-terminal membrane spanning hydrophobic FT domain." FT /db_xref="UniProtKB/TrEMBL:Q9KZS4" FT /protein_id="CAB88818.1" FT /translation="MNSDRLLLIPASLGLVAFVWILRKRLLVRARGVEVDARCYDREWR FT GQGGGPTFLLSFRTADGIKMTCSATESEVPPGTRTGGTVKVRYDPAAPGRVETVITSRR FT PLWKRGDLIGLVVFEAAVLAYILG" FT RBS 96891..96895 FT CDS 96900..99449 FT /transl_table=11 FT /gene="SCO2878" FT /gene_synonym="SCE6.15" FT /product="hypothetical protein SCE6.15." FT /note="SCE6.15, unknown, len: 849 aa. Contains degenerate FT repeats: 3xNR(N/H)TART and 3xAAGEAAAVA(Q/A). The predicted FT product of this CDS is also rich in the amino acid Ala and FT contains coiled-coils between residues 194..257 and FT 587..612." FT /db_xref="UniProtKB/TrEMBL:Q9KZS3" FT /protein_id="CAB88819.1" FT /translation="MSMSAPVHRTSERDSATALAAARQRREEGRTGSSSRSGTSAEQAF FT LGLQSSAGNQAATATVQRARGRSLERTAGSGAARPSSAPGTRRDPAGPARRGSESGTQG FT MEVDPALRDQATAARRTAEEAAATRRHVRAGAEAAAGVARNRHTARTAAGEAAAVAQNR FT NTARTAAGEAAAVAQNRNTARTAAGEAAAVAARRLEEAEAAAAEAAEIERRRRAGAEAA FT AAKARERIAAAEAAAEEEDRLRRRAEAEAVALAEEERRRRLEEEAHPAVVEETRAAVEE FT VTLTAEEREARDARLARLAAGFTPSGRTRRGSDLDARPDTAGLTRRGSDSGIRYAEFGT FT GTWERTDTTRDDTGTTTATEEVAPPAEETAPPAEEARRSEERAAADTRAEVRSDRLKAV FT AENADQGKRLLDPTDALAKGVQAPTAAGLGQEATEMAANAPKPDPGGGSGAEVLKHNAS FT ATGVSGASLSAVTELLSFGASVADSFRNLRTALVKGSGAGYHNAHKKGKTKATDAGMSV FT ASTGANAGTIAKEAVKLQGVASTAASAEASGVLSGVAGVAKSVRAAFKSKGAIEKIHGL FT RQLQKANAAQSQRLLRLEAEANTAELNARFAREAVERARNDRDGRTEDEWAAGIRAAGA FT AYEQAALIEARAKADFLGNARDLEDLTFATNLAKSRKVSQAAKEMGGGVMGEGLKGAGG FT IATVAIVATGALASNPAGWITAAVGAGLVLTTAAYKGGSAAYGRFQEAHHPELYTPEGE FT PIPTAKDTGDSLLHAMKFWKKITRYKRQLAAHKIYNMVSRENTDPALRASALHLLTLIK FT AGHTDHKMEREEWEASLRQPAKKADWIKEITDQLASS" FT repeat_region 97332..97484 FT /note="degenerate repeat region with 3x FT AA(T/C)CGC(C/A)ACACGGCACGGACGGC(G/C)GCAGGCGA(G?A) FT GC(G/A)GCAGCCGT(G/A)GCG(C/G)(A/C)(G/A) repeats" FT CDS 100168..101823 FT /transl_table=11 FT /gene="SCO2879" FT /gene_synonym="SCE6.16" FT /gene_synonym="cvnA12" FT /product="putative membrane protein" FT /note="SCE6.16, cvnA12, possible membrane protein, len: 551 FT aa. Similar to many Streptomyces coelicolor proteins e.g. FT TR:CAB59483 (EMBL:AL132648) putative integral membrane FT protein, SCI41.13C (541 aa), fasta scores opt: 449 z-score: FT 340.7 E(): 1.5e-11 27.5% identity in 564 aa overlap. FT Contains a possible hydrophobic membrane spanning region FT and coiled-coils between residues 120..140" FT /db_xref="GOA:Q9KZS2" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9KZS2" FT /protein_id="CAB88820.1" FT /translation="MTELIVTATAVLAVAGAGAAWYFRRKAGQARRRGEQLREHADRLT FT LQLVAAEQCVGHLAATVIPAAAKGGPGGSGPGGGLLVPAQLDGTPLAERLRAVPGAVAS FT AVGDVRAEERAAAEQAAAHAAERLRQDTERQIAQARRESVGVARAAVRGFANNVVARSA FT RLGRAVSQGVRRHISDEAYETLVEIDHLTQQMLLTASGYSVLAGDKLSRRWPATTLTDI FT VRAAMGRIEGYERIKHPEMGSVVVEGRAVEAVVHALAVLLDNALRYSPPAASVHVSLEQ FT GHHACFLIVDDAGLRMDDERLLWASDVMSGEQRDDITRLGAHPQTGLRVASLLAENYGF FT RVELTAPNIYQGTRAMVVLPKNLIVDPAAAQPAPRPAAQAARPVPAGSATPAAPAAPAT FT PVAPAVAASSVAPPLAPAPEAGVPASAAVAGPAVPAAPGEPVAEPAAAPATSPAGAPAA FT ASVPDPATPTSAATTATTASGLTVRRRSAAPAPARRPAAPDDTEPGRPAVAAAWAAGTR FT RGRDGEQPSPAPAGTATHTAARTTPHDAADDEGH" FT CDS 101826..102248 FT /transl_table=11 FT /gene="SCO2880" FT /gene_synonym="SCE6.17" FT /gene_synonym="cvnB12" FT /product="conserved hypothetical protein SCE6.17." FT /note="SCE6.17, cvnB12, unknown, len: 140 aa. Similar to FT many proteins of undefined function from Streptomyces FT coelicolor e.g. TR:Q9X835 (EMBL:AL049727) SC9B1.15C (139 FT aa), fasta scores opt: 222 z-score: 297.5 E(): 3.9e-09 FT 34.3% identity in 134 aa overlap and TR:CAB61281 FT (EMBL:AL132991) SCF55.11C (152 aa), fasta scores opt: 221 FT z-score: 295.6 E(): 4.9e-09 32.6% identity in 138 aa FT overlap. Contains a Pfam match to entry PF01860 DUF42, FT Protein of unknown function." FT /db_xref="InterPro:IPR004942" FT /db_xref="UniProtKB/TrEMBL:Q9KZS1" FT /protein_id="CAB88821.1" FT /translation="MQDTHTNSLGWLLDQELGSVEGVRYAVLMSSDGLLKARTQTIGQD FT DGEKFAALTAALRAAGKAWDEFTGGAGMRQLLIESVGCIGLTTTAAKNTMLSVCTTGPD FT ADVGLISHHMVRLATRVGHELATEERVPVADGGRPV" FT misc_feature 101874..102200 FT /note="Pfam match to entry PF01860 DUF42, Protein of FT unknown function, score -0.20, E-value 0.0011" FT CDS 102245..102598 FT /transl_table=11 FT /gene="SCO2881" FT /gene_synonym="SCE6.18" FT /gene_synonym="cvnC12" FT /product="conserved hypothetical protein SCE6.18" FT /note="SCE6.18, cvnC12, unknown, len: 117 aa. Similar to FT many proteins of undefined function from Streptomyces FT coelicolor e.g. TR:CAB71243 (EMBL:AL138598) SC1A2.05 (126 FT aa), fasta scores opt: 194 z-score: 251.3 E(): 1.4e-06 FT 38.7% identity in 119 aa overlap and TR:Q9X834 FT (EMBL:AL049727) SC9B1.14C (119 aa), fasta scores opt: 192 FT z-score: 249.3 E(): 1.9e-06 37.9% identity in 124 aa FT overlap." FT /db_xref="InterPro:IPR007995" FT /db_xref="UniProtKB/TrEMBL:Q9KZS0" FT /protein_id="CAB88822.1" FT /translation="MSGPRRDPDMVRPYVRTQGRIRAREDVRLESVVIAATGPTDTLGP FT DARRVMRLFAGADGGLAVADIAAALELPPSTVRILVSSLMDSGHLASPVAAIDDQPDFD FT LLQEVLRGLRSLV" FT CDS 102666..103214 FT /transl_table=11 FT /gene="SCO2882" FT /gene_synonym="SCE6.19" FT /gene_synonym="cvnD12" FT /product="putative conserved ATP/GTP-binding protein" FT /note="SCE6.19, cvnD12, possible ATP/GTP-binding protein, FT len: 182 aa. Highly similar to many other ATP/GTP-binding FT proteins from Streptomyces coelicolor including: FT TR:CAB59480 (EMBL:AL132648) SCI41.10C (176 aa), fasta FT scores opt: 618 z-score: 748.9 E(): 0 58.4% identity in 166 FT aa overlap and TR:Q9X833 (EMBL:AL049727) SC9B1.13C (181 FT aa), fasta scores opt: 588 z-score: 712.9 E(): 2.8e-32 FT 53.4% identity in 176 aa overlap. Contains a Prosite hit to FT PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9KZR9" FT /db_xref="InterPro:IPR004130" FT /db_xref="UniProtKB/TrEMBL:Q9KZR9" FT /protein_id="CAB88823.1" FT /translation="MVAGGFGVGKTTLIGSVSEVRPLRMEEPITQASAGVDDLRGTPHK FT TTTTVAMDFGRIHMAGGRLALYLFGLPGQSRFQPLWEDLAEGALGCLVLADTRDLDASH FT DALGLLDGAGIPYAVAINTFPGSPSYPEAELREALALEPATPLTYCDARDRTSSLHALI FT TLTEYLSEHRSAALLESRR" FT misc_feature 102675..102698 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 103211..104443 FT /transl_table=11 FT /gene="SCO2883" FT /gene_synonym="SCE6.20" FT /product="putative cytochrome P450." FT /note="SCE6.20, possible cytochrome P450, len: 410 aa. FT Highly similar to many other cytochrome P450 proteins from FT Streptomyces including: S. coelicolor TR:CAB61278 FT (EMBL:AL132991) SCF55.08C (420 aa), fasta scores opt: 710 FT z-score: 807.4 E():0 33.1% identity in 411 aa overlap and FT S. violaceus (S. venezuelae) TR:O87605 (EMBL:AF087022) FT cytochrome P450 monooxygenase, PikC (416 aa), fasta scores FT opt: 464 z-score: 529.1 E(): 4.8e-22 30.2% identity in 411 FT aa overlap. Also similar to the adjoining CDS SCE6.21 (408 FT aa), fasta scores opt: 257 z-score: 252.4 E(): 1.5e-08 FT 26.5% identity in 407 aa overlap. Contains a Prosite hit to FT PS00086 Cytochrome P450 cysteine heme-iron ligand FT signature." FT /db_xref="GOA:Q9KZR8" FT /db_xref="InterPro:IPR002397" FT /db_xref="UniProtKB/TrEMBL:Q9KZR8" FT /protein_id="CAB88824.1" FT /translation="MTLPSTETAPTGEPGRIALYAPEFAADPHAAYRSMRRTHGPLVPV FT DLAPGVPATLVIGYYQARRILNDPLRFPADPRAWEKLIPATCPVRPMMEWRPNALRSGG FT AEHTRYRSANTHAIDQVDQHGLRALVEQVASDAIEGFRTAGSADLLTQYSFPIAFRVLS FT ALLGCPDEIGQRIADGMAKIFDTTNADQGNLILAQAVSDLVTLRRTHPGDDITSRLALH FT PVRLTDEEMSHQLVTLYGAGIEPMTNLISNTILKILTDEEFSADLHAGLSTVRDALDAV FT LYTDPPMANYCISYPPYPVDVEGVLLPADQPVVISMAAANNDPALTEGVPAGQHGGNRA FT HLAWSTGPHTCPARSHAYLIAETAVTHLLDALPETDLARPAAELVWRPGPFHRALESLP FT VTFPAAQSAAH" FT misc_feature 104240..104269 FT /note="PS00086 Cytochrome P450 cysteine heme-iron ligand FT signature" FT RBS 104442..104447 FT CDS 104455..105681 FT /transl_table=11 FT /gene="SCO2884" FT /gene_synonym="SCE6.21" FT /product="putative cytochrome P450." FT /note="SCE6.21, possible cytochrome P450, len: 408 aa. FT Highly similar to many other cytochrome P450 proteins FT including: Saccharopolyspora erythraea (Streptomyces FT erythraeus) SW:CPXJ_SACER(EMBL:X60379) 6-deoxyerythronolide FT B hydroxylase (404 aa), fasta scores opt: 777 z-score: FT 888.8 E():0 37.8% identity in 410 aa overlap and FT Streptomyces fradiae TR:Q9XCC6(EMBL:AF145049) (433 aa), FT fasta scores opt: 1253 z-score: 1430.3 E():0 50.9% identity FT in 409 aa overlap. Also similar to the adjoining CDS FT SCE6.20 (410 aa), fasta scores opt: 257 z-score: 252.4 E(): FT 1.5e-08 26.5% identity in 407 aa overlap. Contains a FT PS00086 Cytochrome P450 cysteine heme-iron ligand signature FT and a Pfam match to entry PF00067 p450, Cytochrome P450." FT /db_xref="GOA:Q9KZR7" FT /db_xref="InterPro:IPR002397" FT /db_xref="PDB:1ODO" FT /db_xref="UniProtKB/TrEMBL:Q9KZR7" FT /protein_id="CAB88825.1" FT /translation="MATQQPALVLDPTGADHHTEHRTLREGGPATWVDVLGVQAWSVSD FT PVLLKQLLTSSDVSKDARAHWPAFGEVVGTWPLALWVAVENMFTAYGPNHRKLRRLVAP FT AFSARRVDAMRPAVEAMVTGLVDRLAELPAGEPVDLRQELAYPLPIAVIGHLMGVPQDR FT RDGFRALVDGVFDTTLDQAEAQANTARLYEVLDQLIAAKRATPGDDMTSLLIAARDDEG FT DGDRLSPEELRDTLLLMISAGYETTVNVIDQAVHTLLTRPDQLALVRKGEVTWADVVEE FT TLRHEPAVKHLPLRYAVTDIALPDGRTIARGEPILASYAAANRHPDWHEDADTFDATRT FT VKEHLAFGHGVHFCLGAPLARMEVTLALESLFGRFPDLRLADPAEELPPVPSLISNGHQ FT RLPVLLHAG" FT misc_feature 104707..105675 FT /note="Pfam match to entry PF00067 p450, Cytochrome P450, FT score 208.30, E-value 1.2e-58" FT misc_feature 105493..105522 FT /note="PS00086 Cytochrome P450 cysteine heme-iron ligand FT signature" FT CDS complement(105734..106207) FT /transl_table=11 FT /gene="SCO2885" FT /gene_synonym="SCE6.22c" FT /product="conserved hypothetical protein SCE6.22c." FT /note="SCE6.22c, unknown, len: 157 aa. Highly similar to FT another hypothetical protein from Streptomyces coelicolor FT TR:CAB66282 (EMBL:AL136519) SCC57A.14 (161 aa), fasta FT scores opt: 611 z-score: 780.6 E():0 58.3% identity in 156 FT aa overlap" FT /db_xref="InterPro:IPR003779" FT /db_xref="UniProtKB/TrEMBL:Q9KZR6" FT /protein_id="CAB88826.1" FT /translation="MEARLNLFANPLAGKLLRHINSAGKAVGDSALSAATQELVKIRAS FT QINGCGFCLDMHTKDAAKAGETSLRLNLIAAWREAKVFTDAERAALELTEQGTRIADAS FT GGVSDEAWANAAEHYDEEQLTALVGLIAVINTYNRLNVITQQPAGDYEPGMFG" FT CDS complement(106310..107194) FT /transl_table=11 FT /gene="SCO2886" FT /gene_synonym="SCE6.23c" FT /product="putative hydrolase" FT /note="SCE6.23c, possible hydrolase, len: 294 aa. Similar FT to several including: Mycobacterium sp. TR:Q9ZER0 FT (EMBL:AJ012627) haloalkane dehalogenase, DhaAF (307 aa), FT fasta scores opt: 347 z-score: 425.8 E(): 2.7e-16 27.4% FT identity in 292 aa overlap and Deinococcus radiodurans FT TR:AAF12090 (EMBL:AE002084) epoxide hydrolase-related FT protein (278 aa), fasta scores opt: 402 z-score: 493.2 E(): FT 4.8e-2032.4% identity in 284 aa overlap. Contains a Pfam FT match to entry PF00561 abhydrolase, alpha/beta hydrolase FT fold." FT /db_xref="GOA:Q9KZR5" FT /db_xref="InterPro:IPR000073" FT /db_xref="UniProtKB/TrEMBL:Q9KZR5" FT /protein_id="CAB88827.1" FT /translation="MTTQRPRTYDPPRPRTVTVDGARVACWEAGPPDAEPVVLLHGYPA FT DHRCWRHQVPPLSARHRVITPDLLGWGASDRPLHLSFDYDTEVARVGRLLDALDLDSVN FT LVGHDYGGFLSLGFTQNHPDRVRRLALLNTRAHGTFTRRWYAVFGLLGLLGRNPLLSGP FT ARHLPYAALHRRSLAPLVRAGHLDARVVDGYLDWMAAPEGRRWLLHYFGDYRTPARPEL FT RRRLSGITCPTAVVWGRADPYLSPAIATGLAGSVPRAELTMLDDAGHWVMDERPADVTR FT ALGRLLERTTPNG" FT misc_feature complement(106334..107014) FT /note="Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold, score 100.70, E-value 2.9e-26" FT RBS 107344..107349 FT CDS 107355..107657 FT /transl_table=11 FT /gene="SCO2887" FT /gene_synonym="SCE6.24" FT /product="putative membrane protein." FT /note="SCE6.24, possible membrane protein, len: 100. The FT predicted product of this CDS is rich in the amino acid Ala FT and contains several possible hydrophobic membrane spanning FT domains." FT /db_xref="UniProtKB/TrEMBL:Q9KZR4" FT /protein_id="CAB88828.1" FT /translation="MARVPSAVVAAGGLVGGYGVARWTKKRQLGGAVLAVAGAAAAQQW FT RARAGGKAAGALTAAYVAGFAGSHPLAKKVGAWPAVLGAAGAVALASWAVADRRA" FT CDS complement(107673..108032) FT /transl_table=11 FT /gene="SCO2888" FT /gene_synonym="SCE6.25c" FT /product="conserved hypothetical protein SCE6.25c." FT /note="SCE6.25c, unknown, len: 119 aa. similar to FT TR:CAC46858 (EMBL:AL591790) hypothetical protein from FT Rhizobium meliloti (Sinorhizobium meliloti) (120 aa) fasta FT scores; opt: 360, Z-score: 449.2, E(): 2.2e-17, 48.305% FT identity (49.565% ungapped) in 118 aa overlap. Weakly FT similar in parts to Streptomyces coelicolor FT TR:O86701(EMBL:AL031515) putative lyase, SC5C7.04 (138 aa), FT fasta scores opt: 141 z-score: 193.4 E(): 0.0024 33.3% FT identity in 111 aa overlap." FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/TrEMBL:Q9KZR3" FT /protein_id="CAB88829.1" FT /translation="MSIRRIVPNIHVEAEGQWNTSREFYGLLGFEEVMDMGWVTTLASP FT SNPTAQISLFTEERTAPVVPDLSVEVEDVDAVYAQVVASGAEIVREPQDEEWGVRRFFV FT RDPNGRVINVLTHHA" FT RBS complement(108038..108042) FT CDS complement(108078..109592) FT /transl_table=11 FT /gene="SCO2889" FT /gene_synonym="SCE6.26c" FT /product="putative sugar transport protein." FT /note="SCE6.26c, possible sugar transport protein, len: 504 FT aa. Similar to several Eukaryotic and Prokaryotic transport FT proteins including: Schizosaccharomyces pombe (Fission FT yeast) SW:ITR2_SCHPO(EMBL:Z95334) myo-inositol transporter FT 2 (557 aa), fasta scores opt: 422 z-score: 488.9 E(): FT 8.4e-20 27.6% identity in 467 aa overlap and Bacillus FT subtilis SW:YYAJ_BACSU(EMBL:D26185) hypothetical metabolite FT transport protein (451 aa), fasta scores opt: 420 z-score: FT 487.9 E(): 9.6e-20 27.7% identity in 451 aa overlap. FT Contains a Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter and multiple possible membrane spanning FT hydrophobic domains." FT /db_xref="GOA:Q9KZR2" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9KZR2" FT /protein_id="CAB88830.1" FT /translation="MTAETSSSGSVPASTGTVTTAVPARLDRLPWSRWHWMIVIGLGTV FT WILDGLEVTIVGNVAGRIAEDGSGLDISSAQITGLAAALYVAGACSGALFFGWLTDRHG FT RKKLFMLTLVVYLAATALTAVSFESWWFFLFRFLTGFGIGGEYAAINSAIDELIPSHYR FT GRVDLIINGSYWLGAIGGALLSIVMLDTDIFAKDVGWRLSFALGVVLGLVVLLVRRHVP FT ESPRWQFIHGQGEKADTLVSSVEREIEREKGAKLPPPAGEITIHQRKSIGFGLIAKTVF FT RRYPRRAVLGLSLFIGQAFLYNAITFGFGTILITFFDVPTGSTGYYFAVIAAGNFCGPL FT LLGHLFDTVGRRIMISSTYLLSGVLLFGTAWLFDRGSLTATTMTACWCVVLFFASAGAS FT SAYLTVSEIFPMETRAMAIAFFYALGTAAGGISGPLLFADLTESGVVGDTVLAFQIGAG FT LMCAAGLVAAFLAVKAERRSLEDIAEPLSTAVPETPGTAGPGAKTA" FT misc_feature complement(108135..109493) FT /note="Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter, score 114.60, E-value 1.8e-30" FT RBS complement(109599..109603) FT CDS complement(join(109676..110530,110532..110888)) FT /pseudo FT /transl_table=11 FT /gene="SCO2890" FT /gene_synonym="SCE6.27c" FT /gene_synonym="SCE6.28c" FT /product="putative secreted protein (pseudogene)." FT /note="SCE6.27c, possible secreted protein, pseudogene, FT len: 284 aa. This CDS represents the C-terminus of SCE6.28c FT and is similar to the C-terminal region of Mycobacterium FT tuberculosis TR:O53758(EMBL:AL021933) putative membrane FT protein (456 aa)." FT /note="SCE6.28c, possible secreted protein, pseudogene, FT len: 119 aa. This CDS represents the N-terminus of SCE6.27c FT and is highly similar to the N-terminus of Mycobacterium FT tuberculosis TR:O53758(EMBL:AL021933) putative membrane FT protein (456 aa). Appears to be a shift in reading frame FT after residue 119. Contains a possible N-terminal signal FT sequence." FT /db_xref="PSEUDO:CAD55457.1" FT RBS 111260..111264 FT CDS 111276..112640 FT /transl_table=11 FT /gene="SCO2892" FT /gene_synonym="SCE6.29" FT /product="putative secreted protein." FT /note="SCE6.29, possible secreted protein, len: 454 aa. FT Similar to another putative secreted protein from FT Streptomyces coelicolor: TR:CAB56661(EMBL:AL121596) FT SCF51A.09C (442 aa), fasta scores opt: 614 z-score: 649.3 FT E(): 9.8e-29 31.3% identity in 454 aa overlap. Contains a FT possible N-terminal signal sequence." FT /db_xref="GOA:Q9KZR1" FT /db_xref="InterPro:IPR001087" FT /db_xref="UniProtKB/TrEMBL:Q9KZR1" FT /protein_id="CAB88833.1" FT /translation="MTRGRDGGAGAPPTKHRALLAAIVTLIVAISAAIYAGASADDGSR FT DHALQAGGRLPRGDAAPASTGAWVGAWATAPAAAEPGTETTGLAGRSVRNVVHTSVGGT FT GARITLSNLYGQSPLTVTHASIALAAGPDTAAAIADTMRRLTFGGSARVIIPAGGQVMS FT DTARLAIPYGANVLVTTYSPIPSGPVTYHPQARQTSYLADGDRTADVTAVAYTTPTPYW FT RYLTALDVLSHEADGTVVAFGDSITDGARSQSDANHRWTDVLAARLHEAAGDGRDTPRY FT SVVNEGISGNRLLTSRPGRPADNPSGLSRFQRDVLERTNVKAVVVVLGVNDVLNSPELA FT DRDAILTGLRTLVDRAHARGLRVVGATITPFGGYGGYTEARETMRQEVNEEIRSGRVFD FT TVVDFDKALRDPYDPRRMRSDYDSGDHLHPGDKGYARMGAVIDLAALKGAAPVKA" FT CDS complement(112668..113501) FT /transl_table=11 FT /gene="SCO2893" FT /gene_synonym="SCE6.30c" FT /product="conserved hypothetical protein SCE6.30c." FT /note="SCE6.30c, unknown, len: 277 aa. Similar to several FT proteins of undefined function e.g. Mycobacterium leprae FT TR:Q9Z5H1(EMBL:AL035500) hypothetical 22.1 kd protein (200 FT aa), fasta scores opt: 413 z-score: 443.6 E(): 2.8e-17 FT 41.5% identity in 205 aa overlap. Contains a possible FT coiled-coil between residues 206..226." FT /db_xref="InterPro:IPR012551" FT /db_xref="UniProtKB/TrEMBL:Q9KZR0" FT /protein_id="CAB88834.1" FT /translation="MTDDAPELRASDADRERVAEVLRDALAEGRLDMAEFEERLDATYS FT ARTYGDLAPITRDLPVGGAGAAPRVSMTKEPERDGGWAGRITGGEGSSTWAVAVMSGFQ FT RKGRWTVPRRFNCFAFWGGGEIDLRDADFAAGEVVINCVAIMGGMNVVVPPGVEVVVRG FT IGFMGGFDHSEEGVPGDPGAPRVIVTGFAFWGGVGVERKVTRAERQRLKEERRQEKLER FT RQERERERLERGSGRRELDASRSDGHDRHGLDGLHDLHGGRERELERERERRRDT" FT CDS complement(113535..114599) FT /transl_table=11 FT /gene="SCO2894" FT /gene_synonym="SCE6.31c" FT /product="putative ABC-transport protein, ATP-binding FT component." FT /note="SCE6.31c, possible ABC-transport protein, FT ATP-binding component, len: 354 aa. Similar to many other FT proposed transport proteins e.g. Synechocystis sp. (strain FT PCC 6803) TR:P73329(EMBL:D90905) ABC transporter (326 aa), FT fasta scores opt: 831 z-score: 906.9 E(): 0 45.3% identity FT in 296 aa overlap. Contains a Prosite hit to PS00017 FT ATP/GTP-binding site motif A (P-loop) and a Pfam match to FT entry PF00005 ABC_tran, ABC transporter." FT /db_xref="GOA:Q9KZQ9" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9KZQ9" FT /protein_id="CAB88835.1" FT /translation="MERADMARTAEAADPAGPGPGTAAGADAAVEAEADAFIELDGVEK FT VFDVRRKTGFLKRERRQVRAVDGLSFTVSRGEMVGYIGPNGAGKSTTIKMLTGILTPSG FT GRLRVAGIDPSRERIRLAHRIGVVFGQRTTLWWDLPLIDSYRLMHRMYRIPDARYRENL FT DRCVELLQLQELLDVPVRQLSLGQRMRGDIAAALLHDPEVLYLDEPTIGLDVVSKAKVR FT GFLLDLNAERGTTVLLTTHDLQDIEQLCSRVMVIDHGRLMYDGRLEGLHEAGESERTLV FT VDLERELPPIEAPEPARVVRVEGPRQWLAFPASESAAGLVAGIAARYPLVDLSVREPDI FT ESVIAKMYAERAGA" FT misc_feature complement(113823..114374) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 146.90, E-value 3.5e-40" FT misc_feature complement(114330..114353) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(114608..115495) FT /transl_table=11 FT /gene="SCO2895" FT /gene_synonym="SCE6.32c" FT /product="putative integral membrane transport protein." FT /note="SCE6.32c possible integral membrane transport FT protein, len: 295 aa. Similar to Deinococcus radiodurans FT TR:AAF09789(EMBL:AE001882) conserved hypothetical protein FT (277 aa), fasta scores. Also weakly similar to the FT adjoining CDS SCE6.33c, fasta scores opt: 174 z-score: FT 186.6 E(): 6.9e-05 29.4% identity in 269 aa overlap. FT Contains a Prosite hit to PS00216 Sugar transport proteins FT signature 1 and multiple possible membrane spanning FT hydrophobic domains. Also contains an N-terminal 5xEAA FT repeat sequence." FT /db_xref="InterPro:IPR010390" FT /db_xref="UniProtKB/TrEMBL:Q9KZQ8" FT /protein_id="CAB88836.1" FT /translation="MAEVAEAAEAAEAAEAAEAARTGVRRGRVVEGVRAYGLIAGMWIR FT STMAYRTSFALTAFGNFAMTALDFVAILLMFSRVDALGGYSLPEVAFLYGLSGVSFGLA FT DLAIGSMERLGRRVRDGTLDTLLVRPAPVLAQVAADRFALRRLGRVVQGLLVLGYALVV FT VDIDWTAAKVLLLPVALISGAGIFCAVFVAAGAFQFAAQDASEVANAFTYGGTTMLQYP FT PTVFALDLVRGATFVLPLAFVNWLPASYVLGRPYPLDLPGWVAFTPPLAAAACCALAGL FT AWRAGLRSYRSTGS" FT misc_feature complement(115130..115177) FT /note="PS00216 Sugar transport proteins signature 1" FT repeat_region complement(115436..115480) FT /note="repeat region containing 3x GAGGCGGC(C/G) repeats" FT CDS complement(115488..116294) FT /transl_table=11 FT /gene="SCO2896" FT /gene_synonym="SCE6.33c" FT /product="putative integral membrane protein" FT /note="SCE6.33c, possible integral membrane protein, len: FT 268 aa. Similar to a protein of undefined function from FT Deinococcus radiodurans TR:AAF09788(EMBL:AE001882) FT conserved hypothetical protein (275 aa), fasta scores: opt: FT 521 z-score: 606.4 E(): 2.4e-26 38.6% identity in 272 aa FT overlap. Also weakly similar to the adjoining CDS SCE6.32c, FT fasta scores: opt: 174 z-score: 186.6 E(): 6.9e-05 29.4% FT identity in 269 aa overlap. Contains multiple possible FT membrane spanning hydrophobic domains" FT /db_xref="UniProtKB/TrEMBL:Q9KZQ7" FT /protein_id="CAB88837.1" FT /translation="MSAGSGRLYVAVAAGGFRRYATYRAATAAGVFTNTVFGLILVYTY FT LALWDEKPQLGGYDQAQAVTFVWLGQALLAALAIGGGGFEDELMERIRTGDVAVDLYRP FT ADLQLWWLAADVGRAVFQLLGRGVVPFVFGSLFFPVALPREVSVWAAFLVAVVLAMVVG FT FALRYLVALSAFWLLDGTGVTQMAWLAGLFCSGMLLPLNVFPGVLGDVVRALPWSSLLQ FT GPADVLLGEADPLGTYLFQASWAVALLALGRLVQSAATRRVVVQGG" FT RBS complement(116298..116302) FT CDS 116675..118945 FT /transl_table=11 FT /gene="SCO2897" FT /gene_synonym="SCE6.34" FT /product="probable secreted penicillin-binding protein" FT /note="SCE6.34, probable secreted penicillin-binding FT protein, len: 756 aa. Similar to many including: Bacillus FT subtilis SW:PBPD_BACSU(EMBL:U11882) penicillin-binding FT protein 4 precursor (624 aa), fasta scores opt: 550 FT z-score: 456.8 E(): 5.5e-18 28.1% identity in 572 aa FT overlap and Helicobacter pylori TR:O25319(EMBL:AE000573) FT penicillin-binding protein 1A (659 aa), fasta scores opt: FT 750 z-score: 619.0 E(): 5.1e-27 31.9% identity in 605 aa FT overlap. Contains Pfam matches to entries PF00912 FT Transglycosyl, Transglycosylase and PF00905 Transpeptidase, FT Penicillin binding protein transpeptidase domain as well a FT possible N-terminal signal sequence." FT /db_xref="GOA:Q9KZQ6" FT /db_xref="InterPro:IPR001460" FT /db_xref="UniProtKB/TrEMBL:Q9KZQ6" FT /protein_id="CAB88838.1" FT /translation="MLSTVVVGLLLIVGGFFLGYHLVQIPAANALATKQSNVYLYADGS FT VLARDGEVNRESVGLARISKDAQHAVLAAEDRDFYSESAIDPMAMVRAGWNTATGKGKQ FT SGSTITQQYVKNYYLAQDQTVTRKVKEFFISIKLDREKSKSEILEGYLNTSFFGRGAYG FT IQAAAQAYFGVDAKDLTAAQGAYLASLLNAPSQYDVVAHPENRPAAEARWKYVMNGMAD FT KGWISPSERAAAKFPKPKQSTISTNMSGQRGYVVNIVKKYLIENDIVDEEELGRGGYRI FT TTTLQKDKQDAFVKAVDDKLMSQLDKKERKVDTYVRAGGASVDPKTGKVVAMYNGIDYV FT KQYTPNAVRRDFQVGSTFKPFVFTSAVENHSETQSGQMINPNTRYDGTSERPVQGWSGG FT RYAPENEDHRDYGHVTVREATDKSINAVYAQMAVDVGSDKVKQTAIDLGLSPDTPELTP FT SPSIALGVATASPLDMAEAYATLANHGRHSTYTLVEKVMKDGKQEVELPERREHQAVSR FT ESADTTTSVLRSVVQNGTATAAQAAGRPAAAKTGTAEEDTAAWFAGYTPDLATVVAVMG FT QDPKTAAHKPLYGAMGLARINGGGAPAEIWSQYTRNALKGEPAADFDLQLQDGADVTAP FT PSSDASDEPGDGDESGSGEASDGPGDADEDGTGSETPGDSDSGSTPPGDDGGTESDPPS FT TGGGTPSTGGPSTEPGPTGGGDSGGDDSSNGGTGPGGGDTDGAGGGDSNTGFPGIPVTP FT RRQ" FT misc_feature 116786..117286 FT /note="Pfam match to entry PF00912 Transglycosyl, FT Transglycosylase, score 212.00, E-value 8.9e-60" FT misc_feature 117521..118498 FT /note="Pfam match to entry PF00905 Transpeptidase, FT Penicillin binding protein transpeptidase domain, score FT 75.10, E-value 1.4e-18" FT CDS complement(118939..119259) FT /transl_table=11 FT /gene="SCO2898" FT /gene_synonym="SCE6.35c" FT /gene_synonym="sugE" FT /product="molecular chaperone" FT /note="SCE6.35c, sugE, molecular chaperone, len: 106 aa. FT Highly similar to several proposed molecular chaperones FT e.g. Escherichia coli SW:SUGE_ECOLI(EMBL:X69949) SugE (105 FT aa), fasta scores opt: 394 z-score: 454.4 E(): 7e-18 51.0% FT identity in 104 aa overlap. Contains a Pfam match to entry FT PF00893 DUF7, Integral membrane protein and multiple FT possible membrane spanning hydrophobic domains." FT /db_xref="GOA:Q9KZQ5" FT /db_xref="HSSP:1S7B" FT /db_xref="InterPro:IPR000390" FT /db_xref="UniProtKB/TrEMBL:Q9KZQ5" FT /protein_id="CAB88839.1" FT /translation="MAWVLLFVAGLLEVGWSIGMKYTDGFTRLWPSVFTGAGIVASMML FT LSYAARTLPIGTAYGVWVGIGAAGAAVLGMVVLGEPATAARIFFICLLLVAVVGLKATS FT GH" FT misc_feature complement(118981..119259) FT /note="Pfam match to entry PF00893 DUF7, Integral membrane FT protein, score 120.80, E-value 2.5e-32" FT CDS complement(119420..119776) FT /transl_table=11 FT /gene="SCO2899" FT /gene_synonym="SCE6.36c" FT /product="putative GroES-family molecular chaperone." FT /note="SCE6.36c, possible GroES-family molecular chaperone, FT len: 110 aa. Similar to many members of the GroES FT chaperonin family including: Rhizobium meliloti FT SW:CH13_RHIME(EMBL:M94191) 10 KD chaperonin C (GroES-C) FT (101 aa), fasta scores opt: 172 z-score: 231.3 E(): 1.9e-05 FT 33.7% identity in 101 aa overlap. Contains 2xPfam matches FT to entry PF00166 cpn10, Chaperonins 10 Kd subunit." FT /db_xref="GOA:Q9KZQ4" FT /db_xref="HSSP:1P3H" FT /db_xref="InterPro:IPR001476" FT /db_xref="UniProtKB/TrEMBL:Q9KZQ4" FT /protein_id="CAB88840.1" FT /translation="MSAKRNEHGPQDDKLPIRMLHDRVLVRQDTGEGERRSGGGILIPA FT TAAVGKRLAWAEVVAVGQNVRTVEPGDRVLYDPEDRAEVEVRGVGYVLMRERDLHAVAA FT DRFEGSEDSTGLYL" FT misc_feature complement(119465..119530) FT /note="Pfam match to entry PF00166 cpn10, Chaperonins 10 Kd FT subunit, score 2.00, E-value 41" FT misc_feature complement(119591..119734) FT /note="Pfam match to entry PF00166 cpn10, Chaperonins 10 Kd FT subunit, score 25.30, E-value 1.2e-05" FT CDS complement(119800..120132) FT /transl_table=11 FT /gene="SCO2900" FT /gene_synonym="SCE6.37c" FT /product="putative membrane protein." FT /note="SCE6.37c, possible membrane protein, len: 110 aa. FT Contains a possible membrane spanning hydrophobic domain." FT /db_xref="UniProtKB/TrEMBL:Q9KZQ3" FT /protein_id="CAB88841.1" FT /translation="MADTSDIRTPAQIEADIKRRREVLAETLDELGMRVHPKTIVDDAK FT AKVASSVDHTLGRAYVQVNRVVSDVKAQFVDETGAPRMERVVPVALVVAGVVGLLALGG FT TRRRKR" FT CDS 120227..120694 FT /transl_table=11 FT /gene="SCO2901" FT /gene_synonym="SCE19A.01" FT /gene_synonym="SCE6.38" FT /product="hypothetical protein" FT /note="SCE19A.01, hypothetical protein, partial CDS, len: FT >31 aa; unknown function, similar to members of the alkyl FT hydroperoxide reductase C/thiol-specific antioxidant family FT e.g. TR:O53226 (EMBL:AL021185), bcp, Mycobacterium FT tuberculosis bacterioferritin comigratory protein (157 aa), FT fasta scores; opt: 124 z-score: 238.1 E(): 6.2e-06, 63.3% FT identity in 30 aa overlap" FT /note="SCE6.38, unknown, len: 155 aa. Highly similar to FT many bacterioferritin co migratory proteins which have no FT known function e.g. Escherichia coli FT SW:BCP_ECOLI(EMBL:M63654) bacterioferritin co migratory FT protein, Bcp (156 aa), fasta scores opt: 516 z-score: 621.8 FT E(): 3.3e-27 51.1% identity in 141 aa overlap. Overlaps and FT extends into CDS SCE19A.01 on the adjoining cosmid. FT Contains a Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA FT family." FT /db_xref="GOA:Q9KZQ2" FT /db_xref="InterPro:IPR012335" FT /db_xref="UniProtKB/TrEMBL:Q9KZQ2" FT /protein_id="CAB88842.1" FT /translation="MSERLQPGDPAPAFTLPDADGNEVSLSDHQGRKVIVYFYPAALTP FT GCTKQACDFTDNLELLTGAGYDVIGISPDKPEKLAKFREAESLKVTLLADPDKKVLDAY FT GAFGEKKNYGKTYMGVIRSTIVVDEQGKVERALYNVRATGHVAKIIKDLGI" FT misc_feature 120245..120679 FT /note="Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA FT family, score 129.00, E-value 8.4e-35" FT tRNA 120737..120823 FT /note="tRNA Leu anticodon TAG, Cove score 69.78" FT CDS complement(120840..121442) FT /transl_table=11 FT /gene="SCO2902" FT /gene_synonym="SCE19A.02c" FT /product="conserved hypothetical protein" FT /note="SCE19A.02c, conserved hypothetical protein, len: 200 FT aa; unknown function, similar to many e.g. SW:Y03Q_MYCTU FT (EMBL:Z73902) Mycobacterium tuberculosis hypothetical FT protein (204 aa), fasta scores; opt: 633 z-score: 743.6 FT E(): 0, 52.0% identity in 200 aa overlap. Similar to FT SW:YGGV_ECOLI (EMBL:U28377), yggV, Escherichia coli FT hypothetical protein (197 aa) (49.5% identity in 198 aa FT overlap)" FT /db_xref="GOA:Q9S2H9" FT /db_xref="HSSP:1B78" FT /db_xref="InterPro:IPR002637" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2H9" FT /protein_id="CAB50983.1" FT /translation="MTRLILATRNAGKITELRAILADAGLPHDLVGADAYPHIPDVKET FT GVTFAENALLKAHALAEATGLPAVADDSGLCVDVLNGAPGIFSARWAGRHGDDQANLDL FT LLAQIADIADEHRGAHFACAAALALPDGTERVVEGQLKGTLRHAPAGTGGFGYDPILQP FT EGETRTCAELTAEEKNAISHRGKAFRALVPVVRELLG" FT CDS complement(121489..121893) FT /transl_table=11 FT /gene="SCO2903" FT /gene_synonym="SCE19A.03c" FT /product="putative secreted protein" FT /note="SCE19A.03c, possible secreted protein, len: 134 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Contains probable N-terminal signal sequence and FT appropriately positioned PS00013 Prokaryotic membrane FT lipoprotein lipid attachment site, so may be a lipoprotein" FT /db_xref="UniProtKB/TrEMBL:Q9S2H8" FT /protein_id="CAB50984.1" FT /translation="MAASRHRRLRRTVTAVATVATIALTAGLTTGCDAVDKALDCVRTA FT DAIADSVTELQQAVENADDPTQWEESLNSIDKNLDRIGDQTDNTDVNKAVDDLGKAVDN FT VRTSVENGDETPDLSPVTDAAGELTKVCTP" FT misc_feature complement(121798..121830) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(122051..122788) FT /transl_table=11 FT /gene="SCO2904" FT /gene_synonym="SCE19A.04c" FT /gene_synonym="rph" FT /product="putative ribonuclease PH" FT /note="SCE19A.04c, rph, probable ribonuclease PH, len: 245 FT aa; highly similar to many e.g. SW:RNPH_ECOLI FT (EMBL:X00781), rph, Escherichia coli ribonuclease PH (238 FT aa), fasta scores; opt: 916 z-score: 1116.8 E(): 0, 60.8% FT identity in 240 aa overlap. Contains Pfam match to entry FT PF01138 RNase_PH, 3' exoribonuclease family and PS01277 FT Ribonuclease PH signature" FT /db_xref="GOA:Q9S2H7" FT /db_xref="InterPro:IPR002381" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2H7" FT /protein_id="CAB50985.1" FT /translation="MSRIDGRTPQQLRPVTIERGWSKHAEGSVLVSFGDTKVLCNASVT FT EGVPRWRKGSGEGWVTAEYAMLPRATNTRGDRESVKGRIGGRTHEISRLIGRSLRAVID FT YKALGENTVVLDCDVLQADGGTRTAAITGAYVALADAVAWAQGRKLIKANRKPLTGTVS FT AVSVGIVDGTPLLDLRYEEDVRADTDMNVVCTGDGRFVEVQGTAEAEPFARDELNTLLD FT LATAGCTELAELQRKALDATLER" FT misc_feature complement(122108..122782) FT /note="Pfam match to entry PF01138 RNase_PH, 3' FT exoribonuclease family, score 266.70, E-value 3.1e-76" FT misc_feature complement(122402..122440) FT /note="PS01277 Ribonuclease PH signature" FT CDS complement(122865..123098) FT /transl_table=11 FT /gene="SCO2905" FT /gene_synonym="SCE19A.05c" FT /product="hypothetical protein" FT /note="SCE19A.05c, hypothetical protein, len: 77 aa; FT unknown function, similar to parts of many sugar permeases FT e.g. TR:P96159 (EMBL:U65013), MalX, Vibrio furnissii PTS FT (phosphoenolpyruvate-dependent sugar phosphotransferase FT system) permease for glucose (523 aa), fasta scores; opt: FT 217 z-score: 287.9 E(): 1.1e-08, 48.1% identity in 77 aa FT overlap. Contains Pfam match to entry PF00367 PTS_EIIB, FT phosphotransferase system, EIIB" FT /db_xref="GOA:Q9S2H6" FT /db_xref="HSSP:1O2F" FT /db_xref="InterPro:IPR001996" FT /db_xref="UniProtKB/TrEMBL:Q9S2H6" FT /protein_id="CAB50986.1" FT /translation="MASKAEKIVAGLGGIDNIDEIEGCITRLRTEVNDPALVNEAALKA FT AGAHGVVKMGTAIQVVIGTDADPIAAEIEDMM" FT misc_feature complement(122982..123086) FT /note="Pfam match to entry PF00367 PTS_EIIB, FT phosphotransferase system, EIIB, score 43.00, E-value FT 8.1e-11" FT CDS 123257..124552 FT /transl_table=11 FT /gene="SCO2906" FT /gene_synonym="SCE19A.06" FT /product="putative PTS transmembrane component" FT /note="SCE19A.06, possible PTS transmembrane component, FT len: 431 aa; similar to many PTS FT (phosphoenolpyruvate-dependent sugar phosphotransferase FT system) transmembrane and sugar-binding components e.g. FT TR:Q57071 (EMBL:X93360), GlcA, PtsG, Staphylococcus FT carnosus PTS system, glucose-specific IIABC component (675 FT aa), fasta scores; opt: 1120 z-score: 1260.6 E(): 0, 43.4% FT identity in 431 aa overlap. Similar to the adjacent CDS FT SCE19A.07, possible PTS transmembrane component (416 aa) FT (4.1% identity in 429 aa overlap).The homologous PTS family FT proteins have a C-terminal extension not present in this FT CDS. Contains hydrophobic, possible membrane-spanning FT regions" FT /db_xref="GOA:Q9S2H5" FT /db_xref="InterPro:IPR013013" FT /db_xref="UniProtKB/TrEMBL:Q9S2H5" FT /protein_id="CAB50987.1" FT /translation="MSADSAVSPARARWNTAFQGLQKMGRSLQLPIAVLPAAGILNRLG FT QPDVFGDDGLGWTNVSKVMTGAGGALLDGSLGLPLLFCVGVAIGMAKKADGSTALAAVA FT GFLVYYNVLRQFPEDCPEGSKVVPQIGCQVTDGSGEVTAFVFQNPGVFGGIVMGLLTAY FT FWQRFHRTRLVDWLGFFNGRRLVPIIMAFVAIVFAALCLWVWPPIGDALESFSDWLNGI FT GAWGAGVFGLANRALLVIGLHQFLNVPMWFQFGSYTKPDGTVVHGDINMFLAGDPDAGQ FT FTTGFFPIMMFALPAAALAITHCAKPHRRKEVGGLMLSVGLTSFVTGITEPLEYSFLFI FT APLLYAAHAVLTGVSMAVTWALGVKDGFSFSAGLIDYVINWNLATKPWLIIPIGLCFAV FT VYYVVFRFAITKFDLKTPGREPEEDVEDVTKV" FT repeat_region 123308..123594 FT /note="repeat 1; degenerate 287 bp direct repeat" FT repeat_region 123701..124550 FT /note="repeat 2; degenerate 850 bp direct repeat" FT CDS 124779..126029 FT /transl_table=11 FT /gene="SCO2907" FT /gene_synonym="SCE19A.07" FT /product="putative PTS transmembrane component" FT /note="SCE19A.07, possible PTS transmembrane component, FT len: 416 aa; similar to many PTS FT (phosphoenolpyruvate-dependent sugar phosphotransferase FT system) transmembrane and sugar-binding components e.g. FT SW:PTGB_ECOLI (EMBL:J02618), ptsG, glcA, Escherichia coli FT PTS system, glucose-specific IIBC component (477 aa), fasta FT scores; opt: 1112 z-score: 1244.4 E(): 0, 44.7% identity in FT 396 aa overlap. Similar to the adjacent CDS SCE19A.06, FT possible PTS transmembrane component (431 aa) (64.1% FT identity in 429 aa overlap). The homologous PTS family FT proteins have a C-terminal extension not present in this FT CDS. Contains hydrophobic, possible membrane-spanning FT regions" FT /db_xref="GOA:Q9S2H4" FT /db_xref="InterPro:IPR013013" FT /db_xref="UniProtKB/TrEMBL:Q9S2H4" FT /protein_id="CAB50988.1" FT /translation="MSTATDTAAPAKKRGSGLFQGLQKVGRSLQLPIAVLPAAGIMVRL FT GQDDIFGKDGLGWDKVAAVFNNAGGALTGSLPILFCIGVAIGFAKKADGSTALAAVVGF FT LVYSKVLEAFPVTEAVVQDGADVAATYNDPGVLGGIIMGLLAAVLWQRYHRKKLVDWLG FT FFNGRRLVPIIMAFVGIVVGVFFGLVWEPIGDGISNFGEWMTGLGSGGAALFGGVNRAL FT IPVGMHQFVNTVAWFQLGDFTNSAGDVVHGDITRFLAGDPSAGIFQAGFFPIMMFGLPA FT AALAMAHTARPERRKAVLGMMISLAATSFVTGVTEPIEFSFMFIAPVLYVLHAVLTAIS FT MAITWGLGVHAGFNFSAGFIDYALNWHLATKPWLIIPIGLVFAAIYYVTFRFAIVKFNL FT KTPGREPEEEVEDLTKA" FT repeat_region 124833..125110 FT /note="repeat 1; degenerate 287 bp direct repeat" FT repeat_region 125178..126027 FT /note="repeat 2; degenerate 850 bp direct repeat" FT CDS complement(126124..126876) FT /transl_table=11 FT /gene="SCO2908" FT /gene_synonym="SCE19A.08c" FT /product="conserved hypothetical protein" FT /note="SCE19A.08c, conserved hypothetical protein, len: 250 FT aa; unknown function, similar to hypothetical proteins from FT Mycobacterium leprae, Mycobacterium tuberculosis and FT bacillus subtilis e.g. SW:Y03O_MYCLE (EMBL:U00014) FT Mycobacterium leprae hypothetical protein (284 aa), fasta FT scores; opt: 642 z-score: 777.3 E(): 0, 43.0% identity in FT 256 aa overlap. Similar to SC66T3.08c (EMBL:AL079348) FT S.coelicolor hypothetical protein (270 aa) (36.4% identity FT in 272 aa overlap)" FT /db_xref="GOA:Q9S2H3" FT /db_xref="InterPro:IPR001279" FT /db_xref="UniProtKB/TrEMBL:Q9S2H3" FT /protein_id="CAB50989.1" FT /translation="MKLTVVGCSGSFPSAESACSSYLVEADGFRLLLDMGNGALGELQR FT HCGLYDLDAIFLSHLHADHCIDMCAYFVARYYRHDGGRCAPLPVYGPEGTEHRLTTAYA FT DTPSASSMSEVFDFHTVKPSTFEVGPFTVHTERVAHPVEAYAVRVEHGGRSLTYSGDTG FT ATPVLDELARDTDLFLCEAAFTHGKENIPDLHLNGREAGQSAARAGARRLVLTHIPPWT FT DPAVNLADAREVYDGTVEVAAAGAVYEI" FT CDS 127081..127248 FT /transl_table=11 FT /gene="SCO2909" FT /gene_synonym="SCE19A.09" FT /product="putative membrane protein" FT /note="SCE19A.09, putative membrane protein, len: 55 aa; FT unknown function, improbable CDS suggested by GC frameplot. FT C-terminus is rich in Arg and Pro. Contains possible FT hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9S2H2" FT /protein_id="CAB50990.1" FT /translation="MDTSWWLVFAAVVLLALVATLVDGWGRGGRPRGRGRRPPEGRDER FT DGPGGRGPEN" FT CDS complement(127297..128247) FT /transl_table=11 FT /gene="SCO2910" FT /gene_synonym="SCE19A.10c" FT /product="putative cysteine synthase" FT /note="SCE19A.10c, probable cysteine synthase, len: 316 aa; FT similar to many e.g. SW:CYSM_ECOLI (EMBL:M32101), CysM, FT Escherichia coli cysteine synthase B (303 aa), fasta FT scores; opt: 776 z-score: 884.3 E(): 0, 43.7% identity in FT 293 aa overlap. Highly similar to SW:CYSK_MYCTU FT (EMBL:Z73902) Mycobacterium tuberculosis probable cysteine FT synthase (323 aa) (72.4% identity in 322 aa overlap). Weak FT similarity to the N-terminus of SCF43A.11c (EMBL:AL096837) FT S.coelicolor probable threonine dehydratase (325 aa) (27.2% FT identity in 195 aa overlap). Contains Pfam match to entry FT PF00291 S_T_dehydratase, Pyridoxal-phosphate dependent FT enzymes and PS00901 Cysteine synthase/cystathionine FT beta-synthase P-phosphate attachment site" FT /db_xref="GOA:Q9S2H1" FT /db_xref="HSSP:1O58" FT /db_xref="InterPro:IPR001926" FT /db_xref="UniProtKB/TrEMBL:Q9S2H1" FT /protein_id="CAB50991.1" FT /translation="MRYDSPLAAVGNTPLVRLPRLSPSDDVRIWAKLEDRNPTGSIKDR FT PALHMIEQAEKDGRLTQGCTILEPTSGNTGISLAMAARLKGYRIVCVMPENTSQERRDL FT LTMWGAEIISSPAAGGSNTAVRVAKELSAEHPDWVMLYQYGNPDNAGAHYAGTGPEILA FT DLPSVTHFVAGLGTTGTLMGVGRYLREHKPDVKIVAAEPRYDDLVYGLRNLDEGFVPEL FT YDASVLTTRFSVGSADAVTRTRELLQQEGIFAGVSTGAALHAAIGVGKKAVKAGESADI FT VFVVADGGWKYLSTGVYTAETTEAAIETLHGQLWA" FT misc_feature complement(127384..128232) FT /note="Pfam match to entry PF00291 S_T_dehydratase, FT Pyridoxal-phosphate dependent enzymes, score 332.80, FT E-value 3.8e-96" FT misc_feature complement(128098..128154) FT /note="PS00901 Cysteine synthase/cystathionine FT beta-synthase P-phosphate attachment site" FT CDS complement(128254..128532) FT /transl_table=11 FT /gene="SCO2911" FT /gene_synonym="SCE19A.11c" FT /product="conserved hypothetical protein" FT /note="SCE19A.11c, conserved hypothetical protein, len: 92 FT aa; unknown function, similar to hypothetical proteins from FT other organisms e.g. SW:Y03K_MYCTU (EMBL:Z73902) FT Mycobacterium tuberculosis hypothetical protein (93 aa), FT fasta scores; opt: 341 z-score: 451.3 E(): 8.3e-18, 57.0% FT identity in 93 aa overlap" FT /db_xref="GOA:Q9S2H0" FT /db_xref="InterPro:IPR003749" FT /db_xref="UniProtKB/TrEMBL:Q9S2H0" FT /protein_id="CAB50992.1" FT /translation="MAIEVRIPTILRQYTDGQKAVEGSGDTLAKLFADLETRHTGIQAR FT IVDGEQLRRFVNVYLNDEDVRFLDGIDTKLTDGDSITILPAVAGGMA" FT CDS complement(128632..128775) FT /transl_table=11 FT /gene="SCO2912" FT /gene_synonym="SCE19A.12c" FT /product="hypothetical protein" FT /note="SCE19A.12c, hypothetical protein, len: 47 aa; FT unknown function, possible CDS suggested by GC frameplot" FT /db_xref="UniProtKB/TrEMBL:Q9S2G9" FT /protein_id="CAB50993.1" FT /translation="MRSHSGSRTGNRYDEPMVLLDVSEKAPGTLLVARLHVDLCRLKSA FT IC" FT CDS complement(128807..129229) FT /transl_table=11 FT /gene="SCO2913" FT /gene_synonym="SCE19A.13c" FT /product="conserved hypothetical protein" FT /note="SCE19A.13c, conserved hypothetical protein, len: 140 FT aa; unknown function, similar to hypothetical proteins from FT other organisms e.g. SW:Y03J_MYCTU (EMBL:Z73902) FT Mycobacterium tuberculosis hypothetical protein (146 aa), FT fasta scores; opt: 579 z-score: 694.1 E(): 2.5e-31, 65.0% FT identity in 140 aa overlap and TR:Q54330 (EMBL:M29166) FT Streptomyces kasugaensis CDS from Mec+ region (115 aa) FT (69.8% identity in 116 aa overlap)" FT /db_xref="InterPro:IPR000555" FT /db_xref="UniProtKB/TrEMBL:Q9S2G8" FT /protein_id="CAB50994.1" FT /translation="MLTITQALYDQIVAHAREDHPDEACGVVAGPAGEGRPERFIPMLN FT AARSPTFYEFDSQDLLKLYREMDDRDEEPVVIYHSHTATEAHPSRTDVTYANEPGAHYV FT LVSTADTDGAGEFQFRSFRIVAGEVTEEEVKVVEAY" FT CDS complement(129397..130824) FT /transl_table=11 FT /gene="SCO2914" FT /gene_synonym="SCE19A.14c" FT /product="putative amino acid permease" FT /note="SCE19A.14c, probable amino acid permease, len: 475 FT aa; similar to many amino acid permeases e.g. SW:ANSP_SALTY FT (EMBL:U04851), ansP, Salmonella typhimurium L-asparagine FT permease (497 aa), fasta scores; opt: 1360 z-score: 1551.0 FT E(): 0, 44.4% identity in 455 aa overlap. Similar to FT SC5F2A.17 (EMBL:AL049587) probable amino acid permease (489 FT aa) (44.9% identity in 465 aa overlap). Contains FT hydrophobic, possible membrane-spanning regions. Contains FT Pfam match to entry PF00324 aa_permeases, Amino acid FT permease and PS00218 Amino acid permeases signature" FT /db_xref="GOA:Q9S2G7" FT /db_xref="InterPro:IPR004841" FT /db_xref="UniProtKB/TrEMBL:Q9S2G7" FT /protein_id="CAB50995.1" FT /translation="MTSAQVDTDKAPEEGYERGLNSRQVQMIAIGGAIGVGLFLGAGAN FT IAKAGPSIILMYALAGVIIFFIMRALGELLLYRPVSGSFAEYSREFLGPFFGYFTGWTY FT WLMWVVTGMAELTAAAIYIHYWFPDIPQWVSALVFLVLLFVANLISVKLFGEIEFWFSM FT VKVTAIIGMIVIGVGVLTLGFSQAGDTAAVSNLWEFDGFFPKGIGSSLMTLQGVMFAYL FT AVELVGVTAGESENPEKTLPKAINTLPWRIALFYVGALTVILAVVKWTEFAEGVSPFVE FT AFAVIGIPAGAGIVNFVVLTAALSSCNSGMYSTGRMLRTLADNGEAPRIFNKLSSTKTP FT AIGIAVSVVFMAIGVVLNYLVPEKAFGYVTSVATAAGIWTWLMILISHVRYRRKVVAGR FT LPASSFPAPGGSVCSYIAIAFLLFVTCLIAYDADARVCLYVMAGWAAALGIGWAVLKSR FT NPQITERPGEPEFEKIG" FT misc_feature complement(129454..130779) FT /note="Pfam match to entry PF00324 aa_permeases, Amino acid FT permease, score 584.00, E-value 9.1e-172" FT misc_feature complement(130588..130680) FT /note="PS00218 Amino acid permeases signature" FT CDS complement(131176..131784) FT /transl_table=11 FT /gene="SCO2915" FT /gene_synonym="SCE19A.15c" FT /product="hypothetical protein" FT /note="SCE19A.15c, hypothetical protein, len: 202 aa; FT similar to SW:Y03H_MYCLE (EMBL:U00014) Mycobacterium leprae FT hypothetical protein (222 aa), fasta scores; opt: 192 FT z-score: 222.4 E(): 4.7e-05, 34.6% identity in 188 aa FT overlap and SW:Y03H_MYCTU (EMBL:Z73902) Mycobacterium FT tuberculosis hypothetical protein (218 aa) (32.8% identity FT in 186 aa overlap)" FT /db_xref="InterPro:IPR018561" FT /db_xref="UniProtKB/TrEMBL:Q9S2G6" FT /protein_id="CAB50996.1" FT /translation="MPGQFEPLPGGGAAVALDDVEISIIRSLAVQLLELIGPGPAEDAS FT DDPLAELFAEGPSEPPSDPVLRRLFPDAYGDPEGAPQAREAEEQRAHSAEFRRYTENDL FT RAGKRDNALAVVRTLDTLSSASAGEEGAVLKLSPQESQQWLRALNDLRLAIGSRLEIAD FT EDDTDLLYRLPDEDPRKPMVMAYLWLGGLQESLVATLMP" FT CDS complement(131838..132155) FT /transl_table=11 FT /gene="SCO2916" FT /gene_synonym="SCE19A.16c" FT /product="conserved hypothetical protein" FT /note="SCE19A.16c, conserved hypothetical protein, len: 105 FT aa; similar to SW:Y03G_MYCTU (EMBL:Z73902) Mycobacterium FT tuberculosis hypothetical protein (101 aa), fasta scores; FT opt: 377 z-score: 514.8 E(): 2.4e-21, 60.0% identity in 105 FT aa overlap and SW:Y03G_MYCLE (EMBL:U00014) Mycobacterium FT leprae hypothetical protein (94 aa) (70.3% identity in 74 FT aa overlap)" FT /db_xref="GOA:Q9S2G5" FT /db_xref="InterPro:IPR014719" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2G5" FT /protein_id="CAB50997.1" FT /translation="MGCVTAAAPMEIEKTESAEEVFAVPEPDVPWVTIVHNDPVNLMSY FT VTYVFQSYFGYSKDKATKLMMDVHHKGRAVVSSGSREEMERDVQAMHGYGLWATLQQDR FT K" FT RBS 132334..132338 FT /note="possible RBS" FT CDS 132346..133692 FT /transl_table=11 FT /gene="SCO2917" FT /gene_synonym="SCE19A.17" FT /product="conserved hypothetical protein" FT /note="SCE19A.17, conserved hypothetical protein, len: 448 FT aa; similar to hypothetical proteins from bacteria e.g. FT SW:Y03F_MYCTU (EMBL:Z73902) Mycobacterium tuberculosis FT hypothetical protein (509 aa), fasta scores; opt: 1488 FT z-score: 1661.8 E(): 0, 57.1% identity in 443 aa overlap" FT /db_xref="GOA:Q9S2G4" FT /db_xref="InterPro:IPR015977" FT /db_xref="UniProtKB/TrEMBL:Q9S2G4" FT /protein_id="CAB50998.1" FT /translation="MDVADLGLPVDVPSTALFTDQYELTMLRAALKAGTAGRRSVFEVF FT TRRLPDGRRYGVVAGTGRVLDAVENFRFDADVLRFLREQDIVDEETLDWLAQYRFSGDI FT WGYPEGEVYFPGSPIMRVEGTFGECVLLETVILSILNHDSAIAAAASRMSSAAGPRPLI FT EMGARRTHELAAVAAARSAYVGGFATTSDLAAGFRYNIPTVGTSAHAFTLLHDNERDAF FT RAQVDALGRDTTLLVDTYDVAEAVRTAVEVAGPELGAVRIDSGDLLLVAHRVRQQLDEL FT GATETKIVVTSDLDEYAIASLAAAPVDAYGVGTQLVTGSGHPTASMVYKLVARAESGAE FT GAPLVPVAKKSSGGKTSVGGRKWAARRLDADGHAEAEVVGTGPVPDALADRQLLVELVK FT GGEVVAREPLDAARDRHAAARANLPLSATQLSRGEPVIPTEYAHGGSGS" FT CDS 133798..134385 FT /transl_table=11 FT /gene="SCO2918" FT /gene_synonym="SCE19A.18" FT /product="putative nicotinamidase" FT /note="SCE19A.18, probable nicotinamidase, len: 195 aa; FT highly similar to nicotinamidases e.g. TR:Q50575 FT (EMBL:U59967), PncA, Mycobacterium tuberculosis FT pyrazinamidase/nicotinamidase (186 aa), fasta scores; opt: FT 801 z-score: 921.3 E(): 0, 65.6% identity in 186 aa FT overlap. Contains Pfam match to entry PF00857 FT Isochorismatase, Isochorismatase family" FT /db_xref="GOA:Q9S2G3" FT /db_xref="HSSP:1IM5" FT /db_xref="InterPro:IPR000868" FT /db_xref="UniProtKB/TrEMBL:Q9S2G3" FT /protein_id="CAB50999.1" FT /translation="MRRALIVVDVQNDFCEGGSLAVSGGADVAAAITELIGQAPAGYRH FT VVATRDHHVAPGGHFADNPDYVHSWPAHCVAGTEGVGFHPNFAPAVASGAIDAVFDKGA FT YAAAYSGFEGADENGTGLAEWLRSREIDEVDVVGIATDHCVRATALDAAREGFRTQVLL FT DLTAGVAAETTERALEELREAGVELSGKPVVQ" FT misc_feature 133807..134328 FT /note="Pfam match to entry PF00857 Isochorismatase, FT Isochorismatase family, score 71.30, E-value 2e-17" FT CDS complement(134398..134742) FT /transl_table=11 FT /gene="SCO2919" FT /gene_synonym="SCE19A.19c" FT /product="hypothetical protein" FT /note="SCE19A.19c, hypothetical protein, len: 114 aa; FT unknown function, probable CDS suggested by probable CDS FT suggested by GC frameplot, positional base preference and FT amino acid composition" FT /db_xref="UniProtKB/TrEMBL:Q9S2G2" FT /protein_id="CAB51000.1" FT /translation="MAAGGFCKLPNGTVVVALNLPSPAPASAGSVRFLVHAQNRARALT FT RLRNLGLRSVYLRGNAAPPTPDEITAVLHHPDGLIWRTAPVAGAVGGPDLVQELWHPIR FT ALLRRPTAQT" FT CDS complement(134889..137234) FT /transl_table=11 FT /gene="SCO2920" FT /gene_synonym="SCE19A.20c" FT /product="putative secreted protease" FT /note="SCE19A.20c, probable secreted protease, len: 781 aa; FT similar to SW:INA_BACTL (EMBL:X55436), Ina, Bacillus FT thuringiensis inhibitor A (a protease) (687 aa), fasta FT scores; opt: 924 z-score: 991.3 E(): 0, 32.9% identity in FT 747 aa overlap and TR:O07351 (EMBL:Y00557), PrtV, Vibrio FT cholerae protease precursor (919 aa) (33.2% identity in 794 FT aa overlap). Contains probable N-terminal signal sequence FT and PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature" FT /db_xref="GOA:Q9S2G1" FT /db_xref="InterPro:IPR006025" FT /db_xref="UniProtKB/TrEMBL:Q9S2G1" FT /protein_id="CAB51001.1" FT /translation="MTRRSWTFRTAATTVAFAAAAATFSAAGVAQADSPSRPEAVDRHD FT PSPDKTTRSHDLKGPLSDTQAAQREEALKQVISGNASVKKKDGSNVVQLKSKKGDAKYV FT ELGREKTDKIFTILVEFGDKVDSRYGGDAGPLHNEIAKPNRRTDNSTAWQEDYDQEHFQ FT DLYFGSGKGVNSVKTYYEKQSSGRYSVDGEVSDWVKVPYNEARYGSNKCDPDNCAWYAV FT QDGVTAWIADQKAAGRTDAQIKSQLTQYDQWDRYDFDGDGDFNEPDGYIDHFQIVHAGE FT DESAGGGAQGEDAIWAHRWYAFGTDAGATGPADNKLGGTQIGDTGIWVGDYTIQPENGG FT LGVYAHEYGHDLGLPDHYDTAGGDNSTGFWTLMSSGSWLGTGRNEIGDLPGDMNAWDKL FT QLGWLNYDTAKAGVNSWHKLGLAEYNTKHKQGLVVELPKEKVTTEIVTPAEGETQWWSG FT SGNDLKNTLSRSVDLTGKSAASLTLDGWYDIEADYDFLYTEVSTDGGANWTAIDGTFDG FT NPIQRDGSDKPALSATVDAYGKLVYPLDAYAGKKIDLRFRYQTDGGLAMKGFTADEIAV FT TADGETLFSDNAETADDAWTAVGFTRKGASFTKEYAQYYIAENRQYVSYDKTLKTGPYN FT FGFSERPNWVEHYAYQNGLLIWKWDTSQADNNTSQHPGKGLVLPIDSHPTALKWKDGTV FT MRNRMQAYDSPFSLYRTDGMTLHKADVAKYVPGSKGVSVFNDRKNDYYDPANPTGGVKI FT TDTNTKIKILKEAKNGSTIELEVGPAGR" FT misc_feature complement(136179..136208) FT /note="PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature" FT RBS complement(137241..137246) FT /note="possible RBS" FT CDS 137668..137967 FT /transl_table=11 FT /gene="SCO2921" FT /gene_synonym="SCE19A.21" FT /product="putative membrane protein" FT /note="SCE19A.21, putative membrane protein, len: 99 aa; FT unknown function, probable CDS suggested by probable CDS FT suggested by GC frameplot and positional base preference. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9S2G0" FT /protein_id="CAB51002.1" FT /translation="MAMPRPTAAQFAYGTCTVIFSTLAMLLLSRTSSGPGVALIAVAAL FT ALGLLVAMTVPQPRTRAVSAVPPRRIGVDREPARVPAAARVSAGAGEATRGRAA" FT CDS complement(137981..138427) FT /transl_table=11 FT /gene="SCO2922" FT /gene_synonym="SCE19A.22c" FT /product="putative membrane protein" FT /note="SCE19A.22c, possible membrane protein, len: 148 aa; FT unknown function, weakly similar to TR:O34424 FT (EMBL:AF008220) Bacillus subtilis hypothetical protein (164 FT aa), fasta scores; opt: 137 z-score: 190.5 E(): 0.0028, FT 30.4% identity in 135 aa overlap. Weak similarity to FT adjacent CDS SCE19.23c, hypothetical protein (224 aa) FT (29.1% identity in 158 aa overlap). Contains a hydrophobic, FT possible membrane-spanning region" FT /db_xref="InterPro:IPR010432" FT /db_xref="UniProtKB/TrEMBL:Q9S2F9" FT /protein_id="CAB51003.1" FT /translation="MPPLADSGRRTLARIIDMILVGIVVWLLSWAFNVQEYTVDGDEVS FT VGKSFGQSVIAAVLYIAYDTYMTTRTGQTLGKKWLGMRVANLDNGATPSVQTSLIRALV FT LWIPFAFCCACVWTIIAGGWSFFDKPYKQGLHDKAAKTVVVSTR" FT repeat_region complement(138473..138577) FT /note="repeat 3; 3x degenerate FT CCCCCGCCCCCCGGCGGMGGMGGYCCCTACGGMGGK repeats" FT CDS complement(138864..139538) FT /transl_table=11 FT /gene="SCO2923" FT /gene_synonym="SCE19.23c" FT /product="putative membrane protein" FT /note="SCE19.23c, putative membrane protein, len: 224 aa; FT unknown function, probable CDS suggested by probable CDS FT suggested by GC frameplot, positional base preference and FT amino acid composition. The N-terminus is Pro-rich. Weak FT similarity to adjacent CDS SCE19.22c, hypothetical protein FT (148 aa) (29.1% identity in 158 aa overlap). Contains FT possible hydrophobic membrane spanning regions" FT /db_xref="InterPro:IPR010432" FT /db_xref="UniProtKB/TrEMBL:Q9S2F8" FT /protein_id="CAB51004.1" FT /translation="MPHQAPPPQPAASAPVAAGGPGGGQTSWAQQVHRLAGAGGDEQPV FT APWKPPVEDVFQAAARRQAAARPAGLGKRLAARLIDTVVLGAVAAVAAVPLGIKAVDHV FT NDKIDEAKLSGETVTVWLLDGTTSTYLGIVLAVLLLFGVVYEALPTAKWGRTLGKKLLG FT LEVRDIEAHEPPAFGAALRRWLVYSVPGLLAVGVVGVLWCLFDRPWHQCWHDKAANTFV FT AG" FT repeat_region complement(139589..139693) FT /note="repeat 4; many degenerate AAGGCC repeats" FT CDS 140690..141118 FT /transl_table=11 FT /gene="SCO2924" FT /gene_synonym="SCE19A.24" FT /product="putative regulator" FT /note="SCE19A.24, possible regulator, len: 142 aa; similar FT to TR:P95753 (EMBL:D50051), SsgA, Streptomyces griseus gene FT involved in regulation of sporulation and cell division FT (136 aa), fasta scores; opt: 291 z-score: 368.2 E(): FT 3.6e-13, 37.3% identity in 126 aa overlap and to SC5F2A.05C FT (EMBL:AL049587) S. coelicolor putative regulator (138 aa) FT (38.5% identity in 135 aa overlap)" FT /db_xref="InterPro:IPR006776" FT /db_xref="UniProtKB/TrEMBL:Q9S2F7" FT /protein_id="CAB51005.1" FT /translation="MHTNPTGPTVVERELELRLVLSPESGIPVPARLGYHTDDPYAVHI FT TFHIDSGHPVHWTFARDLLVEGVFRPSGHGDVRVWPSKTEGRSVVLVALSSPDGDALLE FT APTPQVSAWLERTLRAVPPGTEGAQLGIDDGLAELLAR" FT CDS complement(141132..142598) FT /transl_table=11 FT /gene="SCO2925" FT /gene_synonym="SCE19A.25c" FT /product="putative oxidoreductase subunit" FT /note="SCE19A.25c, probable oxidoreductase subunit, len: FT 488 aa; similar to many e.g. SW:GLCD_ECOLI (EMBL:L43490), FT GlcD, Escherichia coli glycolate oxidase subunit (499 aa), FT fasta scores; opt: 1033 z-score: 1172.9 E(): 0, 38.9% FT identity in 460 aa overlap. Also similar to SW:DLD1_YEAST FT (EMBL:X66052), dld, Saccharomyces cerevisiae D-lactate FT dehydrogenase [cytochrome] precursor (587 aa) (29.4% FT identity in 435 aa overlap). The N-terminus differs from FT its homologues and an alternative start codon is present at FT codon 3" FT /db_xref="GOA:Q9S2F6" FT /db_xref="InterPro:IPR006094" FT /db_xref="UniProtKB/TrEMBL:Q9S2F6" FT /protein_id="CAB51006.1" FT /translation="MIMSRIEAPRDEDDAAAAVDSTPGSTPGSPLGDRSTLVGRLLAGL FT PAGSVLTDPDVTASYANDMASFCPAGAPAAVVLPRTVEDVQHVMRTATALRVPVVPQGA FT RTGLSGAANATDGCVVLSLTKMDRILEINPVDRVAVVEPGVVNATLSRAVNEHGLYYPP FT DPSSWEMCTIGGNIGTASGGLCCVKYGVTAEYVLGLDVVLADGRLMSTGRRTAKGVAGY FT DLTRLFVGSEGSLGIVVKAVLGLRPKPPEQLVLAAEFASASAACDAICRIMEGGHVPSL FT LELMDRTTVKAVNDLAHMGLPESTEALLLAAFDTTDPAADLAAVGALCEAAGATQVVPA FT EDAAESELLLQARRLALTALEAVKGTTMIDDVCVPRSRLGDMLEGIDRVAAKYGLTIGV FT CAHAGDGNTHPTVCFDVQDPDESRRARESFDEIMALGLELGGTITGEHGVGVLKKEWLA FT REIGPVGLEMQRAVKEVFDPLGILNPGKLF" FT CDS 142771..144126 FT /transl_table=11 FT /gene="SCO2926" FT /gene_synonym="SCE19A.26" FT /product="putative secreted protein" FT /note="SCE19A.26, putative secreted protein, len: 451 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Alternaive start codons are present at codons 11 and 17. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="GOA:Q9S2F5" FT /db_xref="InterPro:IPR013026" FT /db_xref="UniProtKB/TrEMBL:Q9S2F5" FT /protein_id="CAB51007.1" FT /translation="MLIASVAGAAVLGGVLVLLPRGAGDAPPPAPGPAALARGAVTTGV FT PAALPDLAALIGDRETHLRAHPLDGASWAVLGAAYVEQGRRTADGANWPKAEKALRTSL FT RTGPKRNPQALEGLAALAVARRDFPAAKKWGESAVKAAPKRWTAHAVLIGAYTGLGDDK FT GVGRALDKVMELRPGSAAVGALAAAVYRDRGWREDAAARISDAAAAAGAPAERAAYLEQ FT AGRLAFERGERQEALRFFQEALRTDPDQRAAQAGQGRALAALGRTTEALSAYQAALAKR FT PSPEYALELGELYESLGLGQAARVEYDLLRERARGAEAAGADEQLVLGLLDADHGDPAA FT AVERLRVEWGRQPGTAVADALGWALHRTGADEEALEFATIATDGDKGGGVRSALYVFHR FT GVVEKELGRYGPARRHLGEALTINPYFSPLRVPEAKRALAELGEPPVEGPPD" FT CDS complement(144170..145315) FT /transl_table=11 FT /gene="SCO2927" FT /gene_synonym="SCE19A.27c" FT /product="putative 4-hydroxyphenylpyruvate dioxygenase" FT /note="SCE19A.27c, probable 4-hydroxyphenylpyruvate FT dioxygenase, len: 381 aa; highly similar to many e.g. FT SW:HPPD_STRAW (EMBL:U11864) Streptomyces avermitilis FT 4-hydroxyphenylpyruvate dioxygenase (380 aa), fasta scores; FT opt: 2347 z-score: 2634.5 E(): 0, 91.9% identity in 381 aa FT overlap. Similar to TR:Q9Z4X7 (EMBL:AL035640) S. coelicolor FT probable 4-hydroxyphenylpyruvic acid dioxygenase (325 aa) FT (36.4% identity in 330 aa overlap)" FT /db_xref="GOA:Q9S2F4" FT /db_xref="HSSP:1CJX" FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2F4" FT /protein_id="CAB51008.1" FT /translation="MTQTTHHTPDTARQADPFPVKGMDAVVFAVGNAKQAAHYYSTAFG FT MKLVAYSGPENGSRETASYVLESGSARFVFTSVIKPSTDWGTFLAQHVAEHGDGVVDLA FT IEVPDARAAHAYAVEHGARSLAEPHEVKDEHGTVVLAAIATYGETRHTLVERTGYDGPY FT LPGYVAAKPMVAPPAQRVFQAVDHCVGNVELGRMNEWVGFYNKVMGFTNMKEFVGDDIA FT TEYSALMSKVVADGTLKVKFPINEPAIAKKKSQIDEYLEFYGGAGVQHIALNTNDIVAT FT VRAMRAAGVEFLDTPDSYYDTLGEWAGETRVPVDVLRELKILVDRDEDGYLLQIFTKPV FT QDRPTVFFEMIERHGSMGFGKGNFKALFEAIEREQEKRGNL" FT RBS 145428..145432 FT /note="possible RBS" FT CDS 145441..145932 FT /transl_table=11 FT /gene="SCO2928" FT /gene_synonym="SCE19A.28" FT /product="putative asnC-family transcriptional regulator" FT /note="SCE19A.28, probable asnC-family transcriptional FT regulator, len: 163 aa; similar to SW:ASNC_ECOLI FT (EMBL:K00826), AsnC, Escherichia coli transcriptional FT activator of asparagine synthetase (152 aa), fasta scores; FT opt: 236 z-score: 296.2 E(): 3.7e-09, 31.3% identity in 147 FT aa overlap and to putative asnC-family regulators. Similar FT to SC6G9.10 (EMBL:AL079356) S.coelicolor probable AsnC FT family transcriptional regulator (164 aa) (48.7% identity FT in 156 aa overlap). Contains Pfam match to entry PF01037 FT ASNC_trans_reg, AsnC family" FT /db_xref="GOA:Q9S2F3" FT /db_xref="InterPro:IPR019888" FT /db_xref="UniProtKB/TrEMBL:Q9S2F3" FT /protein_id="CAB51009.1" FT /translation="MAGAGIDRLDGRIIGLLAREPRIGVLEMSRRLGVARGTAQARLDR FT LQSNGVIRGFGPEVDPAALGYPVTAFATLEIRQGQGADVRAHLATVPEVLELHTTTGTG FT DMLCRLVARSNADLQRVIDRVVGFDGIVRAATAIVMENPVPLRIIPLVEQAAQDSGGHD FT " FT misc_feature 145528..145818 FT /note="Pfam match to entry PF01037 ASNC_trans_reg, AsnC FT family, score 58.40, E-value 1.6e-13" FT CDS complement(146054..147103) FT /transl_table=11 FT /gene="SCO2929" FT /gene_synonym="SCE19A.29c" FT /product="putative transposase" FT /note="SCE19A.29c, possible transposase, len: 349 aa; weak FT similarity to TR:Q48345 (EMBL:M24855) ORF within Anabaena FT sp. insertion sequence IS891 (402 aa), fasta scores; opt: FT 271 z-score: 327.3 E(): 6.8e-11, 25.6% identity in 309 aa FT overlap. Weakly similar to SCH35.10 (EMBL:AL078610) FT S.coelicolor probable transposase (407 aa) (26.3% identity FT in 342 aa overlap)" FT /db_xref="InterPro:IPR010095" FT /db_xref="UniProtKB/TrEMBL:Q9S2F2" FT /protein_id="CAB51010.1" FT /translation="MAFAKDLKRRNVLQEAVYHRIKADFDLGAQAAVRTVKKVCDAYAT FT FKANLRAGNYGLEGSKRRIKAESKPVRFRETSAQPFDDRMLTWNLDTKMVSVWTVAGRL FT KGIPFVCSPEAMRLLAQRKGESDLVMRDGMFFLLATIDIPEPEVSGPDGFLGVDLGIVN FT IATTSDGRIMSSRQVNRYRQRKRDLRGKLQKKRTKSAARVLKRQRRKEARYATQRNHII FT ARKLVHTAERTSRGIGLEDLTGIRQRVTAREDQRARLHSWAFAQLGAFVEYKAKRAGVA FT VVHVDPRNTSRQCSECWHTHRTNRVTRARFVCRSCGIVLHADHNGSRNIAHRADAAWQR FT GAANRPRTP" FT CDS 147307..147954 FT /transl_table=11 FT /gene="SCO2930" FT /gene_synonym="SCE19A.30" FT /product="putative permease membrane component" FT /note="SCE19A.30, probable permease membrane component, FT len: 215 aa; similar to components transporters involved in FT osmoregulation e.g. SW:PROW_BACSU (EMBL:U38418), proW, FT Bacillus subtilis glycine betaine/L-proline transport FT system permease protein (217 aa), fasta scores; opt: 413 FT z-score: 474.7 E(): 4.2e-19, 35.1% identity in 211 aa FT overlap. Similar to SCE19A.32, probable permease inner FT membrane component (290 aa) (33.8% identity in 207 aa FT overlap) and to SC9B1.11 (EMBL:AL049727) S.coelicolor FT probable ABC transport permease (221 aa) (31.3% identity in FT 195 aa overlap). Contains hydrophobic, possible FT membrane-spanning regions. May be part of a multicomponent FT transporter which includes SCE19A.30, SCE19A.31, SCE19A.32 FT and SCE19A.33. Contains Pfam match to entry PF00528 FT BPD_transp, Binding-protein-dependent transport systems FT inner membrane component" FT /db_xref="GOA:Q9S2F1" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9S2F1" FT /protein_id="CAB51011.1" FT /translation="MNFWDFLGSRHQQLLADAYQHASAVFQCMVVATLLGVLIGVLTYR FT SDWAGNVATLSTSAILTIPSLAMIGLLIPILGLGVPPTVTALTLYGLLPIVRNSIVGLR FT GVDPALVDAAKGIGMSRPARLLRVELPLAWPPILTGIRVSTQMLMGIAAIAAYASGPGL FT GNEIFRGIASLGSKNALNQVLAGTLGIIVLALLFDAAYVLLGRLTIPRGIRV" FT misc_feature 147610..147822 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 37.20, E-value 3.7e-07" FT CDS 147962..149236 FT /transl_table=11 FT /gene="SCO2931" FT /gene_synonym="SCE19A.31" FT /product="putative ABC transporter ATP-binding protein" FT /note="SCE19A.31, probable ABC transporter ATP-binding FT protein, len: 424 aa; similar to many, including components FT of transporters involved in osmoregulation e.g. FT SW:PROV_BACSU (EMBL:U38418), proV, Bacillus subtilis FT glycine betaine/L-proline transport ATP-binding protein FT (404 aa), fasta scores; opt: 997 z-score: 1092.8 E(): 0, FT 45.7% identity in 359 aa overlap. Similar to SC9B1.09 FT (EMBL:AL049727) S.coelicolor ABC transporter ATP-binding FT subunit (386 aa) (49.0% identity in 365 aa overlap). FT Contains an approx. 20 aa N-terminal extension absent FT similar proteins. May be part of a multicomponent FT transporter which includes SCE19A.30, SCE19A.31, SCE19A.32 FT and SCE19A.33. Contains Pfam match to entry PF00005 FT ABC_tran, ABC transporter, PS00211 ABC transporters family FT signature and PS00017 ATP/GTP-binding site motif A FT (P-loop)" FT /db_xref="GOA:Q9S2F0" FT /db_xref="HSSP:1L2T" FT /db_xref="InterPro:IPR017871" FT /db_xref="UniProtKB/TrEMBL:Q9S2F0" FT /protein_id="CAB51012.1" FT /translation="MSGSVSDDGRGEASGGTTGATIELEALTKRYPGSPQPAVENVSME FT IKAGETVIFVGPSGCGKSTTLKMINRLIEPSGGRIRINGEDVTDIDPVKLRRKVGYAIQ FT SSGLFPHMTVAQNIALVPRMIGWSKARIRERVEEMLDLVGLDAGEFHGRYPRQLSGGQQ FT QRVGVARALAADPPVLLMDEPFGAVDPITRDHLQDELIRLQHELHKTIVFVTHDFDEAI FT KLGDRIAVLRERSHIAQFDTPEAILTNPADDFVSGFVGAGAALKRLNLTRVRDVGITDY FT PTVTVEDPLQDIFDRLRESGTNEILLLDRRGRPYKWLRRGDLMRARGSLARAGTLVHDT FT VTRDATLRDALEAVLTDNAGRVAVTGRRGAYEGVVDMETLMNSVHELLEADRLDALEHQ FT HDLEETRATQTHTEQEGFGEVGGRA" FT misc_feature 148106..148663 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 239.40, E-value 5e-68" FT misc_feature 148127..148150 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 148433..148477 FT /note="PS00211 ABC transporters family signature" FT CDS 149233..150105 FT /transl_table=11 FT /gene="SCO2932" FT /gene_synonym="SCE19A.32" FT /product="putative permease membrane component" FT /note="SCE19A.32, probable permease membrane component, FT len: 290 aa; similar to many, including components of FT transporters involved in osmoregulation e.g. SW:PROW_BACSU FT (EMBL:U38418), proW, Bacillus subtilis glycine FT betaine/L-proline transport system permease protein (217 FT aa), fasta scores; opt: 429 z-score: 461.7 E(): 2.2e-18, FT 37.7% identity in 220 aa overlap. Similar to SCE19A.30, FT probable permease inner membrane component (215 aa) (33.5% FT identity in 209 aa overlap) and SC9B1.11 (EMBL:AL049727) FT probable ABC transport permease (221 aa) (37.6% identity in FT 186 aa overlap). Contains an approx. 50 aa N-terminal FT extension absent from similar proteins and hydrophobic, FT possible membrane-spanning regions. May be part of a FT multicomponent transporter which includes SCE19A.30, FT SCE19A.31, SCE19A.32 and SCE19A.33. Contains Pfam match to FT entry PF00528 BPD_transp, Binding-protein-dependent FT transport systems inner membrane component and PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign." FT /db_xref="GOA:Q9R432" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9R432" FT /protein_id="CAB51013.1" FT /translation="MSGSPRPSPGRRPAGEHEVEGVAFRDEAGDEEEVAAPPPSPPAAG FT PRVGWRKLTFLPVVLIAVLLATWLWFRQADLDALSQNALGNGQVTKALWQHVQLTVIST FT FFVLIIAIPLGILLTRRAFRKATPFAMAFANMGQATPAIGLLALLVIWLGIGRRAALIG FT IIVYAVLPVLSNTIAGLKANDPTLLEAARGIGMSPLGVLTRVELPLAVPLILAGVRTAL FT VLNVGTATLATFGGGGGLGVLITTGITSQRMPVLVLGSILTVALALLVDWLASLAELLL FT RPRGLEVGT" FT misc_feature 149767..149979 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 51.60, E-value 1.7e-11" FT misc_feature 149770..149856 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS 150102..151070 FT /transl_table=11 FT /gene="SCO2933" FT /gene_synonym="SCE19A.33" FT /product="putative permease binding-protein component" FT /note="SCE19A.33, probable permease binding-protein FT component, len: 322 aa; similar to SW:PROX_BACSU FT (EMBL:U38418), proX, Bacillus subtilis glycine FT betaine-binding protein precursor (313 aa), fasta scores; FT opt: 300 z-score: 341.4 E(): 1.1e-11, 27.5% identity in 320 FT aa overlap and to similar putative permease components. FT Similar to SC9B1.12 (EMBL:AL049727) S.coelicolor probable FT secreted substrate-binding protein (320 aa) (30.4% identity FT in 329 aa overlap). Contains a probable N-terminal signal FT sequence and appropriately positioned PS00013 Prokaryotic FT membrane lipoprotein lipid attachment site. May be part of FT a multicomponent transporter which includes SCE19A.30, FT SCE19A.31, SCE19A.32 and SCE19A.33" FT /db_xref="GOA:Q9X4J2" FT /db_xref="InterPro:IPR007210" FT /db_xref="UniProtKB/TrEMBL:Q9X4J2" FT /protein_id="CAB51014.1" FT /translation="MRRRTCWALAAALLSASAGCGLTSGSPMVDDVEPGSIGRGKPLDG FT ADLTVTSKEFTEQLVLGAIMGIAFEAAGAEVLDRTGIQGSVGTRAAVENGDADATYEYT FT GTAWITYLGNSRPIPDPEQQWKAVKEADAKKGLTWLEPARLNNTYALAMNQANYKKYRT FT KTLSEVTALSKSDPGAVTLCVEGEFANRADGLPGLEKAYGMSLPAGNITQMDTGIIYTQ FT TAKGACTYGEVYTTDGRIKSMNLVVMEDDKKFFPNYNAAPMVRTATLKKWPAIASVLDP FT VTRALTNDVAQTLNAKVDMDGQDPHQVALDWMKEKGFVKEG" FT misc_feature 150129..150161 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(151095..151874) FT /transl_table=11 FT /gene="SCO2934" FT /gene_synonym="SCE19A.34c" FT /product="putative secreted protein" FT /note="SCE19A.34c, possible secreted protein, len: 259 aa; FT unknown function, similar to parts of hypothetical proteins FT e.g. TR:O53340 (EMBL:AL021646) Mycobacterium tuberculosis FT hypothetical protein (340 aa), fasta scores; opt: 396 FT z-score: 436.5 E(): 5.6e-17, 34.4% identity in 337 aa FT overlap, but with significant indels with respect to that FT sequence. Very weak similarity to the C-termini of FT ATP-dependent proteases e.g. SW:LON_CAUCR (EMBL:U56652), FT lon, Caulobacter crescentus ATP-dependent protease (799 aa) FT (31.5% identity in 178 aa overlap). Contains a probable FT N-terminal signal sequence" FT /db_xref="UniProtKB/TrEMBL:Q9S2E9" FT /protein_id="CAB51015.1" FT /translation="MLSRLTRPQFLAVCGLPVVALLATALFAPLPFSVAQPGLTADVLG FT KNRGAEVITISGAPTHATSGQLRMTTIEATGPDASIRLGDVLGSWFDTDRAVMPRDAVY FT PSGDDVSEIERYNQEQMKESQDSATTAALRYLRMDKGDVDVKLRLEDVGGPSAGLLFSL FT GIVDKLGAGDLTGGKVVAGTGTITDGGKVGAVGGVPLKTQAARRDGATVFLVPKAECSD FT AQAELPKGLRLIPVTTLEGAVDSLKALESGKGDVPAC" FT CDS complement(151930..152592) FT /transl_table=11 FT /gene="SCO2935" FT /gene_synonym="SCE19A.35c" FT /product="putative transcriptional regulator" FT /note="SCE19A.35c, probable transcriptional regulator, len: FT 220 aa; similar to many e.g. SW:ICLR_ECOLI (EMBL:M31761), FT IclR, Escherichia coli acetate operon repressor (274 aa), FT fasta scores; opt: 206 z-score: 234.8 E(): 9.6e-06, 29.2% FT identity in 154 aa overlap. Similar to TR:O05148 FT (EMBL:U89712), hppR, Rhodococcus globerulus putative FT regulator of 3-(3-hydroxyphenyl)propionic acid catabolic FT pathway (206 aa) (44.8% identity in 174 aa overlap). FT Contains probable helix-turn-helix motif at aa 27-48 (Score FT 1663, +4.85 SD)" FT /db_xref="GOA:Q9R3R2" FT /db_xref="InterPro:IPR014757" FT /db_xref="UniProtKB/TrEMBL:Q9R3R2" FT /protein_id="CAB51016.1" FT /translation="MTAETSQTLDRGLRVLKLLADTDHGLTVTELSHKLGVNRTVVYRL FT LATLEQHALVRRDLGGRARVGLGVLGLGRQVHPLVREAAMPALRALAEDIGATAHLTLV FT DGAEALAVAVVEPTWTDYHVAYRAGFRHPLERGAAGKAILAARQPSQPTGGEAVDDPGY FT TLTHGELEAGACGAAAPLLGVTGVEGSVGVVMLADVVPERVGERVKHAAREVAEALR" FT RBS complement(152601..152605) FT /note="possible RBS" FT CDS complement(152894..154690) FT /transl_table=11 FT /gene="SCO2936" FT /gene_synonym="SCE19A.36c" FT /product="conserved hypothetical protein" FT /note="SCE19A.36c, conserved hypothetical protein, len: 598 FT aa; unknown function, similar to mycobacterial hypothetical FT proteins SW:Y065_MYCTU (EMBL:Z74697) Mycobacterium FT tuberculosis hypothetical protein (626 aa), fasta scores; FT opt: 1921 z-score: 2072.6 E(): 0, 56.1% identity in 567 aa FT overlap and TR:O33011 (EMBL:Z97369) Mycobacterium leprae FT hypothetical protein (596 aa) (55.7% identity in 566 aa FT overlap). Contains PS00017 ATP/GTP-binding site motif A FT (P-loop)" FT /db_xref="GOA:Q9S2E8" FT /db_xref="InterPro:IPR014001" FT /db_xref="UniProtKB/TrEMBL:Q9S2E8" FT /protein_id="CAB51017.1" FT /translation="MTTTASSSTSHHLSPAFPGRAPWGTAGKLRAWQQGAMEKYLQDQP FT RDFLAVATPGAGKTTFALTLASWLLHHHVVQQVTVVAPTEHLKKQWAEAAARIGIKLDP FT EYSAGPLSREYQGIAITYAGVGVRPMLHRNRVEQRKTLVILDEIHHAGDSKSWGEACLE FT AFEPATRRLALTGTPFRSDTNPIPFVAYEEGNDGIRRSAADYTYGYGSALADGVVRPVI FT FMSYSGNMRWRTKAGDEIAARLGEPMTKDAVSQAWRTALDPRGEWMPAVLRAADQRLTE FT VRKAIPDAGALVIAADQDSARAYAKLIREITGDKATVVLSDDTGASKNIDAFSASTDRW FT MVAVRMVSEGVDVPRLAVGVYATTISTPLFFAQAVGRFVRSRRRGETASVFLPTVPDLL FT TFANEMERERDHVLDKPKKEGEEDPYAESEKEMDEANREQDEDTGEQEQFAFEALESEA FT TFDRVMYNGAEFGMQAHPGSEEEQDYLGIPGLLEPDQVQLLLQKRQARQIAHSRKKPDD FT EADLLELPAERRPVVSHKELMELRKQLNTMVGAYVHQSGKPHGVIHTELRRVCGGPPSA FT EATGGQLRQRIAKVQEWATRMK" FT misc_feature complement(154514..154537) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(154846..156297) FT /transl_table=11 FT /gene="SCO2937" FT /gene_synonym="SCE56.01c" FT /gene_synonym="SCE19A.37c" FT /product="putative transmembrane transport protein" FT /note="SCE56.01c, possible transport protein (partial), FT len: >170 aa; similar to TR:AAF11647 (EMBL:AE002045) FT Deinococcus radiodurans conserved hypothetical protein FT DR2098, 462 aa; fasta scores: opt: 330 z-score: 380.0 E(): FT 9.3e-14; 37.4% identity in 155 aa overlap and to TR:O69070 FT (EMBL:AF079900) Streptomyces rimosus tetracycline efflux FT protein OtrB, 563 aa; fasta scores: opt: 271 z-score: 312.6 FT E(): 5.3e-10; 34.8% identity in 158 aa overlap. Contains FT possible hydrophobic membrane spanning regions" FT /note="SCE19A.37c, possible transmembrane transport FT protein, partial CDS, len: >344 aa; weak similarity to FT transport proteins, many hypothetical e.g. TR:Q50392 FT (EMBL:U40487), lfrA, Mycobacterium smegmatis proton FT antiporter efflux pump (504 aa), fasta scores; opt: 220 FT z-score: 251.9 E(): 1.1e-06, 27.8% identity in 345 aa FT overlap. Weak similarity to part of others from FT S.coelicolor e.g. TR:Q9ZBJ1 (EMBL:AL035161) S.coelicolor FT probable efflux protein (815 aa) (27.2% identity in 345 aa FT overlap). Contains hydrophobic, possible membrane-spanning FT regions" FT /db_xref="GOA:Q8CJY2" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q8CJY2" FT /protein_id="CAD55458.1" FT /translation="MTVPEPRDTDVAAPVEPALAPAAPAETVLSRAYRALSIGIVSVIV FT LIAFEATAVGTAMPVAARELDGVSLYAFAFSGYFTTSLFGMVLSGQWSDRRGPLAPLTT FT GIATFAAGLVLSGTAGAMWLFILGRAVQGFGGGLVIVALYVVVGRAYPERLRPAIMAAF FT AAGWVVPSVVGPLASGAVTEHLGWRWVFVGIPVLVVVPLALALPQIRSRASGPVGGGDT FT PASFDGRRIRLALAISLGAGLLQYAAQDLRWVSLLPGAAGVALLVPAVLGLLPRGTYRA FT VRGLPSVVLLRGVAAGSFIAAESFVPLMLVTQRGLSPTLAGLSLAAGGATWAGGSWLQS FT RPRLEPHRERLMALGMLLVAAAITTAPSVLIEAVPAWTVAVAWAFGCFGMGLVISSTSV FT LLLKLSAPEEAGTNSAALQISDGLSNVVLLSAGGAAFAALGGGTVSHTATEATGSHPAA FT FAVVFLPMAAVALAGAWVATRIRER" FT RBS 156683..156686 FT CDS 156688..157698 FT /transl_table=11 FT /gene="SCO2938" FT /gene_synonym="SCE56.02" FT /product="putative oxidoreductase" FT /note="SCE56.02, possible oxidoreductase, len: 336 aa; FT similar to TR:CAB61562 (EMBL:AL133171) Streptomyces FT coelicolor putative aldo/keto reductase (fragment) FT SCF81.28c, 307 aa; fasta scores: opt: 1370 z-score: 1572.6 FT E(): 0; 65.2% identity in 305 aa overlap and to FT SW:NORA_ASPFL (EMBL:U32377) Aspergillus flavus norsolorinic FT acid reductase (EC 1.1.1.-) NorA, 388 aa; fasta scores: FT opt: 572 z-score: 659.1 E(): 2.7e-29; 32.8% identity in 329 FT aa overlap" FT /db_xref="GOA:Q9L1S0" FT /db_xref="HSSP:1LQA" FT /db_xref="InterPro:IPR001395" FT /db_xref="UniProtKB/TrEMBL:Q9L1S0" FT /protein_id="CAB72221.1" FT /translation="MRYIRLGTTGLEVSAIALGCMGFGEPDRGGEPWSLGADPSRDIIR FT QALEGGVNFLDTANGYSAGNSEEIVGQAVKDFARREEVVLSTKVWMRMRPGPNGAGLSR FT KAIFAELDASLKRLGTDYIDLYQIHRWDYDTPIEETLEALHDVVKSGKVRYLGASSMYA FT WQFAKALYLADLNGWTRFVSMQDHYNLIHREAEREMLPLCADQGIGVIPWSPLARGRLT FT RARDTATARAGTDEGGRILYRDEDQAVAERVREIAGRRGLSPAQVALAWVMRNPVVTSP FT IVGVTKPAQLADAIAAVDVGLDEDEAAYLEEPYQPHEAAYLEESFYKARPAAASR" FT CDS complement(157665..158447) FT /transl_table=11 FT /gene="SCO2939" FT /gene_synonym="SCE56.03c" FT /product="hypothetical protein SCE56.03c" FT /note="SCE56.03c, unknown, len: 260 aa" FT /db_xref="UniProtKB/TrEMBL:Q9L1R9" FT /protein_id="CAB72222.1" FT /translation="MVARSLRRSANGSRRHADGHTFSGETMHAVTGGTTITRGAAADVR FT TAVPSLVTRVRLATTVEDPARTRDAARRPQASGERPSLWNTSTLMSCLLLAVSHRAEPG FT TSRDLPPRFLDREFGRHRVTRFEDIDFPRTLTHEPTRRFLRETGLPEDARPFRLDADDL FT PLPTLAEYCEEHPDQPVPPGADHLVRLGRLADGAHVAVDGTTGAVLTWRTPDGTLHPLV FT SDVSALALTLWALRRAGRLETSAGGGPDYREAAAGRAL" FT CDS complement(158541..160862) FT /transl_table=11 FT /gene="SCO2940" FT /gene_synonym="SCE56.04c" FT /product="putative oxidoreductase" FT /note="SCE56.04c, possible oxidoreductase, len: 773 aa; FT similar to TR:Q9ZBN7 (EMBL:AL034492) Streptomyces FT coelicolor putative oxidoreductase SC6C5.08, 828 aa; fasta FT scores: opt: 1088 z-score: 1144.8 E(): 0; 42.2% identity in FT 782 aa overlap and to SW:XDH_DROPS (EMBL:M33977) Drosophila FT pseudoobscura xanthine dehydrogenase (EC 1.1.1.204) Xdh, FT 1342 aa; fasta scores: opt: 517 z-score: 540.4 E(): FT 1.1e-22; 27.4% identity in 762 aa overlap. Contains Pfam FT match to entry PF01315 Ald_Xan_dh_C, Aldehyde oxidase and FT xanthine dehydrogenase, C terminus" FT /db_xref="GOA:Q9L1R8" FT /db_xref="InterPro:IPR008274" FT /db_xref="UniProtKB/TrEMBL:Q9L1R8" FT /protein_id="CAB72223.1" FT /translation="MSNDAATAEAEGTAEAATPVPDPIPHGLGASLPPADARAKTEGTF FT PYAADLWAEGLLWAAVLRSPHPRARIVSIDTTHAREMPGVRAVVTHEDVPGSPLHGRGG FT QADRPVFASEAVRHHGEPLAAVAADHPDTARMAAAAVIVEYELLDPVTDPEQAFEAEPL FT HPDGNLIRHIPLRHGDPDAAGEIVVEGLYRIGRQDPAPIGAEAGLAVPRPDGGVELYLA FT STDPHGDRDIAAACYGLSPEQVKIVVTGVPGATADREDQGFQLPLGLLALKTGCPVKLT FT ATREESFLGHTHRHPTLLRYRHHADAEGRIVKVEAQILLDAGAYADTSSDALAAAVAFA FT CGPYVVPNAFIEGWAVRTNNPPSGHVRGEGAMQVCAAYEAQMDKVAKKLGLDPAEVRLR FT NVLATGDVLPTGQTVTCPAPVAELLQAVRDFPLPALPKDTPEDEWLLPGGPEGAGEPGA FT VRRGVGYGIGMVHMLGAEGADEVSTATVKVQGGVATVLCAAVETGQGFTTLARQIVQDT FT LGVDEVQVAPVDTDQPPAGPGCRGRHTWVSGGAVERAAKMVRTQLLQPLAHQFGMSTEL FT LQIADGKITSYDGVLSTTVTEALDGKELWATAQCRPHPTEPLDEAGQGDAFVGMAFCAI FT RAVVDVDIEIGSVRVVELAVAQDVGRVLNPAQLTARIEAGVTQGVGIALTENLRTPRGL FT IRHPDLTGYALPTALDAPDIRIVKLVEERDVVAPFGAKAVSAVPVVASPAAVASAVRAA FT TGRPVNRLPIRPQAAVATGH" FT misc_feature complement(158727..160739) FT /note="Pfam match to entry PF01315 Ald_Xan_dh_C, Aldehyde FT oxidase and xanthine dehydrogenase, C terminus, score FT 279.60, E-value 3.9e-80" FT CDS complement(160859..163180) FT /transl_table=11 FT /gene="SCO2941" FT /gene_synonym="SCE56.05c" FT /product="conserved hypothetical protein SCE56.05c" FT /note="SCE56.05c, unknown, len: 773 aa; similar to FT C-terminal region of TR:Q9VYQ2 (EMBL:AE003488) Drosophila FT melanogaster CG2779 protein, 1612 aa; fasta scores: opt: FT 651 Z-score: 464.7 E(): 3e-18; 31.405% identity in 847 aa FT overlap. High content in proline, glycine and alanine. FT Contains Pfam matches to entries PF00111 fer2, 2Fe-2S FT iron-sulfur cluster binding domains and PF01799 fer2_2, FT [2Fe-2S] binding domain and match to Prosite entry PS00197 FT 2Fe-2S ferredoxins, iron-sulfur binding region signature" FT /db_xref="GOA:Q9L1R7" FT /db_xref="HSSP:1FFV" FT /db_xref="InterPro:IPR001041" FT /db_xref="UniProtKB/TrEMBL:Q9L1R7" FT /protein_id="CAB72224.1" FT /translation="MTDDQHGDPHGDQHGQGTPPGGSRWDPLPQGDYDDGATAFVKLPE FT GGVDALLASSDSPLAAPGHGYVPPQITVAPATTAGTDPAATGSWAAPSAPSAPVDGTQW FT QVPDAGQDPAAHQGYGGYPAQQDPYGGAAPYDVHAGQGAPGHDDRFAYQPGPTGQWDFS FT QAAQAAQASRAEADAAAARQASGQDVTGQWSIPVADGDLPDESGEFTTSSLAEQWGTGA FT PATLPGGAPAPWATQPAGQPWGEDAPRPGPAGPADEERPAASGHAYGATATGHGEGHGA FT DAGHRADADLSGYGPGHDSGADAGHGPDAAVGPHGPGPSAPGAGPVPHAHGPGSTASGP FT GEGHGPGPAASVHGHDPAVSPDGPRPADGSYAHAPGVDTQSAAGAAGAGPGVRAPDGAP FT EGSGTATDGPRGAEEAPEGPAGRSAGPHEEARAGSRPEAAEGPVTDRAPTAGRERAPEP FT AGEHGQAPEGEPRPESPAAPQGVPADASDRADSPDPADPADPIDPTDPTGRGTDAADAG FT SGADGPEAVTDGVPDAAQEPSAPAGPQDEHPLASYVLRVNGADRPVTDAWIGESLLYVL FT RERLGLAGAKDGCSQGECGACNVQVDGRLVASCLVPSVTAAGSEVRTVEGLATDGRPSD FT VQRALARRGAVQCGFCVPGMAMTVHNLLEGNPAPTELEARQALCGNLCRCSGYRGVLEA FT VQEVVAEREAHADADAQAGPDPEEPRIPHQAGPGAGGVNPAAFEAQPPPGAQDATGAHD FT RPPYGDHGDHGTHGRDGGHA" FT RBS complement(160869..160873) FT misc_feature complement(161090..161314) FT /note="Pfam match to entry PF01799 fer2_2, [2Fe-2S] binding FT domain, score 115.20, E-value 1.2e-30" FT misc_feature complement(161336..161524) FT /note="Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur FT cluster binding domains, score 13.10, E-value 0.073" FT misc_feature complement(161390..161416) FT /note="PS00197 2Fe-2S ferredoxins, iron-sulfur binding FT region signature" FT misc_feature complement(161663..161707) FT /note="intraprotein repeat 5x (PDX)" FT CDS complement(163177..164097) FT /transl_table=11 FT /gene="SCO2942" FT /gene_synonym="SCE59.01c" FT /gene_synonym="SCE56.06c" FT /product="putative oxidoreductase" FT /note="SCE59.01c, possible oxidoreductase (partial), len: FT >116 aa; similar to N-terminal region of TR:Q9ZBN9 FT (EMBL:AL034492) Streptomyces coelicolor putative FT oxidoreductase subunit SC6C5.06, 296 aa; fasta scores: opt: FT 223 z-score: 268.2 E(): 1.6e-07; 37.6% identity in 93 aa FT overlap and to TR:P95637 (EMBL:U65440) Rhodopseudomonas FT palustris 4-hydroxybenzoyl-CoA reductase HbaD subunit, 327 FT aa; fasta scores: opt: 193 z-score: 233.2 E(): 1.4e-05; FT 42.6% identity in 94 aa overlap" FT /note="SCE56.06, possible oxidoreductase (partial), len: FT >221 aa; similar of TR:Q9ZBN9 (EMBL:AL034492) Streptomyces FT coelicolor putative oxidoreductase subunit SC6C5.06, 296 FT aa; fasta scores: opt: 393 z-score: 443.2 E(): 2.8e-17; FT 34.7% identity in 222 aa overlap and to TR:P95637 FT (EMBL:U65440) Rhodopseudomonas palustris FT 4-hydroxybenzoyl-CoA reductase HbaD subunit, 327 aa; fasta FT scores: opt: 159 z-score: 184.7 E(): 0.0071; 32.1% identity FT in 184 aa overlap" FT /db_xref="GOA:Q8CJY1" FT /db_xref="HSSP:1FFU" FT /db_xref="InterPro:IPR016169" FT /db_xref="UniProtKB/TrEMBL:Q8CJY1" FT /protein_id="CAD55459.1" FT /translation="MGQREGAVGLTTHAPQAAQAVTLPTTLDEAVAALTALPAAVPVAG FT GTDLMAAVNSGQLRPAALVGLGRISEIRGWQYQDGHALLGAGLTHARMGRPDFAALIPA FT LAAAARAAGPPQIRNAGTLGGNIASAAPTGDALPVLAALEATLIIAGPDGARREMPVSH FT LLAGMEMLRAGELIGYVRVPLLHAPQVFLKATGRTGPGRATASVALVLDPARRGVRCAV FT GAIAPMPLRPLEAEQWVASLIDWDNGRAVVPEALHGFGEYVAAACIPDAVPDEDGSVPQ FT LPPAVLHLRRTVAALARRALGRALS" FT RBS complement(163189..163193) FT CDS complement(164313..165950) FT /transl_table=11 FT /gene="SCO2943" FT /gene_synonym="SCE59.02c" FT /product="putative sugar hydrolase" FT /note="SCE59.02c, probable sugar hydrolase, len: 545 aa; FT similar to TR:Q9ZH39 (EBML:AF072374) Pseudoalteromonas sp. FT S9 beta-N-acetylglucosaminidase ChiQ, 783 aa; fasta scores: FT opt: 1378 z-score: 1537.3 E(): 0; 41.6% identity in 512 aa FT overlap and to SW:HEX1_VIBFU (EMBL:U41417) Vibrio furnissii FT beta-hexosaminidase (EC 3.2.1.52) ExoI, 611 aa; fasta FT scores: opt: 1023 z-score: 1142.5 E(): 0; 40.0% identity in FT 487 aa overlap. Contains Pfam match to entry PF00728 FT Glyco_hydro_20, Glycosyl hydrolase family 20" FT /db_xref="GOA:Q9L1V1" FT /db_xref="HSSP:1M03" FT /db_xref="InterPro:IPR001540" FT /db_xref="UniProtKB/TrEMBL:Q9L1V1" FT /protein_id="CAB72189.1" FT /translation="MTDLTDVTDATDVIPRPRHAVAQDACFDLGPDTRLVADEGAGHTE FT RWLRATLGAATGLPLAPGEGGGGAVRLSLDGELADEGYRLDIAPDGVRLTGGGPAGLFW FT GAQTLRQLLGPDAFRRAPLPGRRWRLPLGRIEDAPRFGWRGLMLDVSRHFMPKDGVLRQ FT LDLMAAHKLNVLHFHLTDDQGWRIEIKRHPKLTGTGSWRSRTKFGHRASPLWEDKPHGG FT YYTQEDIREIVAYAAARHITVLPEIDVPGHSQAAIAAYPELGNTDVIDTTALSVWDTWG FT VSPNVLAPTENTLRFYEGVFEEVLELFPSEFVHIGGDECPKDQWRASATAQARMAELGL FT ADEDELQSWFIQHFDTWLAGRGRRLIGWDEILEGGLAKGAAVSSWRGYAGGIAAARAGH FT DVVMCPEQQVYLNFREDGGEDEPVPIAFVRTLEDVYRFEPVPAELTPEESGHVIGTQAN FT LWTEVTENQERVDYQLFPRLAAFAEVAWSALPAPADRDYAAFERRMATHYRRLDALGVA FT YRPPAGPRPWQRRPGVLGRPMDGPPPNK" FT misc_feature complement(164841..165548) FT /note="Pfam match to entry PF00728 Glyco_hydro_20, Glycosyl FT hydrolase family 20, score 199.70, E-value 4.4e-56" FT CDS complement(165955..166800) FT /transl_table=11 FT /gene="SCO2944" FT /gene_synonym="SCE59.03c" FT /product="putative sugar transporter membrane protein" FT /note="SCE59.03c, possible sugar transporter membrane FT protein, len: 281 aa; similar to TR:CAB59590 FT (EMBL:AL132662) Streptomyces coelicolor putative sugar FT transporter inner membrane protein SCF11.13, 285 aa; fasta FT scores: opt: 730 z-score: 883.7 E(): 0; 42.1% identity in FT 278 aa overlap and to TR:AAF11008 (EMBL:AE001988) FT Deinococcus radiodurans ABC transporter, permease protein, FT MalFG family DR1436, 283 aa; fasta scores: opt: 645 FT z-score: 781.7 E(): 0; 38.2% identity in 272 aa overlap. FT Contains Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component and match to Prosite entry PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="GOA:Q9L1V0" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9L1V0" FT /protein_id="CAB72190.1" FT /translation="MNLLRARVRRPWRLAAEVSALLIAVVVAFPLYWMVLSAFKPAGEI FT ESSEPRPWTLTPSLDSFRRVFEQQEFGRYFLNSLIVAGSVVIASALIAFLAATAVTRFR FT FRFRTTLLIMFLVAQMVPVEALTIPLFFLMRDFGQLNTLGSLILPHIAFSLPFAIWMLR FT GFVKAVPEALEEAAYIDGASRTRFLWQILFPLVLPGLVATSVFSFISTWNDFLFAKSFI FT ISDTSQSTLPMALLVFYKPDDPDWGGVMAASTVMTIPVLVFFVLVQRRLVSGLGGAVKD FT " FT misc_feature complement(166087..166308) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 58.90, E-value 1.1e-13" FT misc_feature complement(166219..166305) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign" FT CDS complement(166797..167747) FT /transl_table=11 FT /gene="SCO2945" FT /gene_synonym="SCE59.04c" FT /product="putative sugar transporter membrane protein" FT /note="SCE59.04c, possible sugar transporter membrane FT protein, len: 316 aa; similar to TR:CAB59589 FT (EMBL:AL132662) Streptomyces coelicolor putative sugar FT transporter inner membrane protein SCF11.12, 302 aa; fasta FT scores: and to TR:CAB55533 (EMBL:AL117322) Streptomyces FT coelicolor putative binding-protein-dependent transport FT protein SCF1.13, 317 aa; fasta scores: opt: 527 z-score: FT 611.6 E(): 1.2e-26; 33.1% identity in 302 aa overlap. FT Contains Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component. Contains also possible hydrophobic membrane FT spanning regions" FT /db_xref="GOA:Q9L1U9" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9L1U9" FT /protein_id="CAB72191.1" FT /translation="MSSGGVVRGRVRRRRGLSRSSPRPFRGSSSTPWLYLAPALVVLGG FT LLVYPVYQLGLISFLEYTQAQVSGGEPATFQGFGNYAELFGDGEFWRVLLATVVFAAAC FT VVSTLAVGCALAVLLTRVRAVPRLALMLAGLGAWATPAVTGSTVWLLLFDPDFGPVNRM FT LGLGDHSWTYGRYSAFLLVLLEVVWCSFPFVMVTVYAGIRAVPSEVLEAAALDGASQWR FT IWRSVLAPMLRPILVVVTIQSVIWDFKVFTQIYVMTNGGGIAGQNMVLNVYAYQKAFAS FT SQYSLGSAIGVVMLLILLAVTLVYLRLLRRQGEEL" FT RBS complement(166803..166806) FT misc_feature complement(166917..167147) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 53.80, E-value 3.8e-12" FT CDS complement(167759..169057) FT /transl_table=11 FT /gene="SCO2946" FT /gene_synonym="SCE59.05c" FT /product="putative sugar transporter sugar-binding protein" FT /note="SCE59.05c, possible sugar transporter sugar-binding FT protein, len: 432 aa; similar to TR:CAB59588 FT (EMBL:AL132662) Streptomyces coelicolor putative sugar FT transporter sugar-binding protein SCF11.11, 422 aa; fasta FT scores: opt: 538 z-score: 581.0 E(): 6e-25; 27.0% identity FT in 429 aa overlap and to SW:MALX_STRPN (EMBL:L08611) FT Streptococcus pneumoniae maltose/maltodextrin-binding FT protein precursor MalX, 423 aa; fasta scores: opt: 299 FT z-score: 325.5 E(): 1e-10; 26.0% identity in 431 aa FT overlap. Contains Pfam match to entry PF01547 FT SBP_bacterial_1, Bacterial extracellular solute-binding FT protein and correctly situated match to Prosite entry FT PS00013 Prokaryotic membrane lipoprotein lipid attachment FT site. Contains also possible N-terminal region signal FT peptide sequence" FT /db_xref="GOA:Q9L1U8" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:Q9L1U8" FT /protein_id="CAB72192.1" FT /translation="MKLAPRLAVLLAAAVVAATACAPQASDNSSSGKDEKSGTLRVWLF FT QEVNNKPKEKVVDAALADFEKAHADTKVTVEYIPVETRAQRIKAAFNDPKSAPDVVEFG FT NTDTAGYVKDGGLADISEEFAAWDEAKDADSTARQSVTVDGKVYGAPYFVGVRALYYRT FT DVFDELGLKAPRTLAELASTAKRVRAAKPDLYGLAVGGAYTYGAMPFIWANGGDIATGK FT GGSYASAIDSAAAQKGIKAYTSLFGDANCPAAKCAGMTGNDTVTAFASGKAAMAIGGDF FT SHQAMEAGAVKGKYAVVPLPGVEPGSIAPAFAGGNNIGVLKSTSHRTLAVDLMKRLASK FT KAQGELFDAMGFLPTFTDVRQQVAAREPFVKPFVDTLAAGTKFVPASPAWATIDSSLVL FT PTMFQEVVSGKKDVGAAAGDAARKMDDAFGSAG" FT misc_feature complement(167780..168628) FT /note="Pfam match to entry PF01547 SBP_bacterial_1, FT Bacterial extracellular solute-binding protein, score FT 111.10, E-value 2.1e-29" FT misc_feature complement(168995..169027) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT RBS complement(169066..169071) FT CDS complement(169301..169594) FT /transl_table=11 FT /gene="SCO2947" FT /gene_synonym="SCE59.06c" FT /product="hypothetical protein SCE59.06c" FT /note="SCE59.06c, hypothetical protein, len: 97 aa; similar FT to TR:O07209 (EMBL:Z96072) Mycobacterium tuberculosis FT hypothetical 9.0 kD protein MTCY05A6.29, len: 82 aa; fasta FT scores: opt: 200 z-score: 268.5 E(): 1.5e-07; 51.6% FT identity in 62 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9L1U7" FT /protein_id="CAB72193.1" FT /translation="MAVMSTLEPERGTGTGTLVEPTPQTSHGDGDHERFAHYVQKDKIM FT ASALDGTPVVALCGKVWVPGRDPKKYPVCPMCKEIYESMSGGGDEGKGGDKK" FT CDS complement(169616..170197) FT /transl_table=11 FT /gene="SCO2948" FT /gene_synonym="SCE59.07c" FT /product="conserved hypothetical protein" FT /note="SCE59.07c, hypothetical protein, len: 193 aa; FT similar to various hypothetical proteins, e.g. TR:P71608 FT (EMBL:Z80233) Mycobacterium tuberculosis hypothetical 21.8 FT kD protein CY10H4.38, 202 aa; fasta scores: opt: 525 FT z-score: 594.5 E(): 1.1e-25; 46.7% identity in 182 aa FT overlap" FT /db_xref="InterPro:IPR003774" FT /db_xref="UniProtKB/Swiss-Prot:Q9L1U6" FT /protein_id="CAB72194.1" FT /translation="MSGMTEVSSLTGRLLVATPALADPNFERAVVLLLDHDEEGSLGVV FT LNRPTPVDVGDILEDWADLAGEPGVVFQGGPVSLDSALGVAVVPGGASGERAPLGWRRV FT HGAIGLVDLEAPPELLAPAVGALRIFAGYAGWGPGQLEDELTEGAWYVVESEPGDVSSP FT FPERLWREVLRRQRGDLAMVATYPDDPSLN" FT CDS 170422..171768 FT /transl_table=11 FT /gene="SCO2949" FT /gene_synonym="murA" FT /gene_synonym="SCE59.08" FT /product="UDP-N-acetylglucosamine transferase" FT /note="SCE59.08, murA, UDP-N-acetylglucosamine transferase, FT len: 448 aa; identical to TR:BAA85335 (EMBL:AB033486) FT Streptomyces lividans UDP-N-acetylglucosamine transferase FT MurA, 446 aa and similar to SW:MURA_ECOLI (EMBL:M92358) FT Escherichia coli UDP-N-acetylglucosamine FT 1-carboxyvinyltransferase (EC 2.5.1.7) MurA, 419 aa; fasta FT scores: opt: 660 z-score: 763.5 E(): 0; 35.7% identity in FT 437 aa overlap" FT /db_xref="GOA:Q9L1U5" FT /db_xref="HSSP:1DLG" FT /db_xref="InterPro:IPR005750" FT /db_xref="UniProtKB/TrEMBL:Q9L1U5" FT /protein_id="CAB72195.1" FT /translation="MTVNGADDVLLVHGGTPLEGEIRVRGAKNLVPKAMVAALLGSAPS FT RLRNVPDIRDVRVVRGLLQLHGVTVRPGEEPGELVLDPTHVESANVADIDAHAGSSRIP FT ILFCGPLLHRLGHAFIPGLGGCDIGGRPIDFHFDVLRQFGAKIEKRADGQYLEAPQRLR FT GTKINLPYPSVGATEQVLLTAVLAEGVTELSNAAVEPEIEDLICVLQKMGAIIAMDTDR FT TIRVTGVDELGGYTHRALSDRLEAASWASAALATEGNVYVRGAQQRSMMTFLNTFRKVG FT GAFEIDDEGIRFWHPGGRLKSIALETDVHPGFQTDWQQPLVVALTQATGLSIVHETVYE FT SRLGFTSALNQMGAHIQLYRECLGGSDCRFGQRNFLHSAVVSGPTKLEGADLVIPDLRG FT GFSYLIAALAAQGTSRVHGIDLINRGYENFMDKLVELGAKVELPGKALG" FT stem_loop complement(171785..171826) FT CDS complement(171953..172234) FT /transl_table=11 FT /gene="SCO2950" FT /gene_synonym="hup" FT /gene_synonym="SCE59.09c" FT /product="DNA-binding protein Hu (hs1)" FT /note="SCE59.09, hup, DNA-binding protein Hu (hs1), len: 93 FT aa; identical to SW:DBH_STRLI (EMBL:AB001381) Streptomyces FT lividans DNA-binding protein hu (HS1) Hup, 93 aa and highly FT similar to SW:DBH_BACSU (EMBL:X66448) Bacillus subtilis FT DNA-binding protein II (HB) (HU), 92 aa; fasta scores: opt: FT 237 z-score: 311.2 E(): 6.4e-10; 40.9% identity in 93 aa FT overlap. Contains Pfam match to entry PF00216 FT Bac_DNA_binding, Bacterial DNA-binding protein" FT /db_xref="GOA:P0A3H5" FT /db_xref="HSSP:1P71" FT /db_xref="InterPro:IPR000119" FT /db_xref="UniProtKB/Swiss-Prot:P0A3H5" FT /protein_id="CAB72196.1" FT /translation="MNRSELVAALADRAEVTRKDADAVLAAFAEVVGDIVSKGDEKVTI FT PGFLTFERTHRAARTARNPQTGEPIQIPAGYSVKVSAGSKLKEAAKGK" FT misc_feature complement(171962..172234) FT /note="Pfam match to entry PF00216 Bac_DNA_binding, FT Bacterial DNA-binding protein, score 117.40, E-value FT 1.4e-32" FT RBS complement(172242..172246) FT CDS complement(172587..174002) FT /transl_table=11 FT /gene="SCO2951" FT /gene_synonym="SCE59.10c" FT /product="putative malate oxidoreductase" FT /note="SCE59.10c, probable malate oxidoreductase, len: 471 FT aa; similar to SW:MAOX_BACST (EMBL:M19485) Bacillus FT stearothermophilus NAD-dependent malic enzyme (EC 1.1.1.38) FT (NAD-ME) 478 aa; fasta scores: opt: 1778 z-score: 1887.0 FT E(): 0; 58.8% identity in 471 aa overlap and to FT SW:MAO2_ECOLI (EMBL:AE000333) Escherichia coli FT NADP-dependent malic enzyme (EC 1.1.1.40) MaeB, 759 aa; FT fasta scores: opt: 1092 z-score: 1158.4 E(): 0; 46.4% FT identity in 394 aa overlap Contains two Pfam matches to FT entry PF00390 malic, Malic enzyme" FT /db_xref="GOA:Q9L1U4" FT /db_xref="InterPro:IPR012302" FT /db_xref="UniProtKB/TrEMBL:Q9L1U4" FT /protein_id="CAB72197.1" FT /translation="MATAPSVSYSMTVRLEVPAGGTAVSQLTTAVESAGGSVTGLDVTA FT SGHDKLRIDVTIAAGSTAHADEIVEQLRGIEGVSLGKVSDRTFLMHLGGKIEMQSKHPI FT RNRDDLSMVYTPGVARVCMAIAENPEDARRLTIKRNSVAVVTDGSAVLGLGNIGPKAAL FT PVMEGKAALFKRFAGIDAWPICLDTQDTDAIVEIVKAIAPGFAGINLEDISAPRCFEIE FT ARLREALDIPVFHDDQHGTAIVVLAALTNALRVVGKGIENVRVVMSGAGAAGTAILKLL FT LAAGVKNAVVADIHGVVHTGRADLVDAAPESALRWIADNTNPEGLTGTLKEAVHGADVF FT IGVSAPNVLDGEDVAAMADGAIVFALANPDPEVDPAIARETAAVVATGRSDFPNQINNV FT LVFPGVFRGLLDAQSRTVNTEMMLAAAHALANVVTEDEINPNYIIPSVFNDKVAGAVAG FT AVRDAAKAAGVVA" FT misc_feature complement(172686..172841) FT /note="Pfam match to entry PF00390 malic, Malic enzyme, FT score 29.60, E-value 2e-06" FT misc_feature complement(173163..173315) FT /note="Pfam match to entry PF00390 malic, Malic enzyme, FT score 22.30, E-value 0.00013" FT RBS complement(174011..174015) FT CDS complement(174437..176671) FT /transl_table=11 FT /gene="SCO2952" FT /gene_synonym="SCE59.11c" FT /product="putative helicase protein" FT /note="SCE59.11c, possible helicase protein, len: 744 aa; FT similar to TR:O32215 (EMBL:Z99121) Bacillus subtilis YvgS FT protein, 774 aa; fasta scores: opt: 346 z-score: 378.5 E(): FT 1.1e-13; 23.1% identity in 808 aa overlap and to C-terminal FT region of SW:UVRD_MYCLE (EMBL:U00016) Mycobacterium leprae FT probable DNA helicase II homolog (EC 3.6.1.-) UvrD, 457 aa; FT fasta scores: opt: 155 z-score: 172.1 E(): 0.036; 26.6% FT identity in 241 aa overlap. Contains Pfam match to entry FT PF01443 Viral_helicase1, Viral (Superfamily 1) RNA helicase FT and match to Prosite entry PS00017 ATP/GTP-binding site FT motif A (P-loop). Contains possible helix-turn-helix motif FT at residues 638..659 (+2.82 SD)" FT /db_xref="GOA:Q9L1U3" FT /db_xref="InterPro:IPR014016" FT /db_xref="UniProtKB/TrEMBL:Q9L1U3" FT /protein_id="CAB72198.1" FT /translation="MEQAHLDRVYRRLEEKIHEAEFLMHDAAQRGHVGTPGALAERDAQ FT VFRAGIHLNRLNNEFEDFLFGRIDLLLGKDGKKGPDGAYTAVEPADGALGPDGTADIAE FT TLHIGRIGVLDEDYAPLVIDWRAPAAAPFYRSTPVDPGRVVRRRVIRSKGRRVLGVEDD FT LMRPEITARLDGEELAVVGDGALMAALGQARTHSMRDIVASIQAEQDRVIRAPAASVTY FT VEGGPGTGKTAVALHRAAYLLYQDRRRYAGGILIVSPTPLLVAYTEGVLPSLGEEGQVA FT IRAIGSLADDAAGAEATLYDSPATARAKGSARMLRVLRRAARGALEPADSPTLLRVVAF FT GRRLELEAEELAGIRRTVLGGTAPVNLLRPRARRLLLDALWEKSGAGARHSDPELAAEL FT RSSFDEDVSSEDSFTGFLDAWWPELTPGAVLAAMADERRLGRWARRVLNPGEVRKVARS FT LRREGHSVHDIALLDELQAIVGTPARPRKRREQDPLDQLTGLDELMPQREETQWERAER FT LAQERTEYAHVIVDEAQDLTPMQWRMVGRRGRHATWTVVGDPAQSSWSDPDEAAAARDE FT ALGSRPRRRFELTVNYRNPAEIAELAAKVLALAMPGSTSPSAVRSTGVEPRFAVVEESL FT ARTVRAEAARLLGLVDGTVGVVVAMNRREEARRWLAGLGDRVVALGSLEAKGLEYDATV FT VVSPAEIADESPAGLRVLYVALTRATQQLTVVSGERDEPDASGVPDLLRD" FT misc_feature complement(174491..174622) FT /note="Pfam match to entry PF01443 Viral_helicase1, Viral FT (Superfamily 1) RNA helicase, score 23.30, E-value 5.1e-06" FT misc_feature complement(175976..175999) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(176781..176785) FT CDS complement(176856..177644) FT /transl_table=11 FT /gene="SCO2953" FT /gene_synonym="SCE59.12c" FT /product="putative membrane protein" FT /note="SCE59.12c, possible membrane protein, len: 262 aa; FT similar to TR:CAB63193 (EMBL:AL133469) Streptomyces FT coelicolor putative membrane protein SCM10.32, 216 aa; FT fasta scores: opt: 204 z-score: 218.0 E(): 9.9e-05; 37.2% FT identity in 253 aa overlap. Contains possible hydrophobic FT membrane spanning region" FT /db_xref="InterPro:IPR010916" FT /db_xref="UniProtKB/TrEMBL:Q9L1U2" FT /protein_id="CAB72199.1" FT /translation="MQGTPAPNEHETVGAYALGILDDAEATAFEAHLATCEWCAQQLDE FT LAGMEPMMAALADLPGTGTPAVAESLTVKPSARLSEKLVDEVAERRASKRRRNFYLVGT FT AAALIIGGPFAAVATTGGGGGGGDDGGGRRAEATQQAASPAESAFAAMPDRVTATDPGT FT QVSATVALEKKAWGTETVLELKNLKGPQKCSLIAVGKNGERETLTSWSVPDWGYGIPGA FT TTEKAKKPLYVHGGAAFEPNQISHFEVMTFDGKRLVEVDA" FT CDS complement(177704..178288) FT /transl_table=11 FT /gene="SCO2954" FT /gene_synonym="SCE59.13c" FT /product="putative RNA polymerase sigma factor" FT /note="SCE59.13c, probable RNA polymerase sigma factor, FT len: 194 aa; similar to TR:CAB63191 (EMBL:AL133469) FT Streptomyces coelicolor putative RNA polymerase sigma FT factor SCM10.30, 184 aa; fasta scores: opt: 522 z-score: FT 641.7 E(): 2.5e-28; 54.7% identity in 161 aa overlap and to FT SW:SIGY_BACSU (EMBL:D83026) Bacillus subtilis RNA FT polymerase sigma factor SigY, 178 aa; fasta scores: opt: FT 211 z-score: 266.1 E(): 2.1e-07; 27.2% identity in 169 aa FT overlap Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 FT factor (ECF subfamily) PS01063 Sigma-70 factors ECF FT subfamily signature" FT /db_xref="GOA:Q9L1U1" FT /db_xref="InterPro:IPR007630" FT /db_xref="UniProtKB/TrEMBL:Q9L1U1" FT /protein_id="CAB72200.1" FT /translation="MGVRKDSVVANERGARARHRMSQSSSEPDEELMRALYREHAGPLL FT AYVLRLVAGDRQRAEDVVQETLIRAWKNAGQLNRATGSVRPWLVTVARRIVIDGHRSRQ FT ARPQEVDPSPLEVIPAEDEIDKALWLMTLSDALDDLTPAHREVLVETYFKGRTVNEAAQ FT TLGIPSGTVRSRVFYALRSMKLALEERGVTA" FT misc_feature complement(177953..178153) FT /note="Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 FT factor (ECF subfamily), score 45.00, E-value 1.7e-09" FT misc_feature complement(178016..178114) FT /note="PS01063 Sigma-70 factors ECF subfamily signature" FT RBS complement(178289..178292) FT CDS complement(178413..179003) FT /transl_table=11 FT /gene="SCO2955" FT /gene_synonym="SCE59.14c" FT /product="conserved hypothetical protein SCE59.14c" FT /note="SCE59.14c, hypothetical protein, len: 196 aa; FT similar to various hypothetical proteins, e.g. TR:CAB56723 FT (EMBL:AL121600) Streptomyces coelicolor hypothetical 22.2kD FT protein SCF76.03, 204 aa; fasta scores: opt: 357 z-score: FT 403.5 E(): 4.6e-15; 37.4% identity in 187 aa overlap" FT /db_xref="InterPro:IPR010852" FT /db_xref="UniProtKB/TrEMBL:Q9L1U0" FT /protein_id="CAB72201.1" FT /translation="MALGTATDPYELRFDTGRISLDLIATTHPAERLDSVDALRAWITG FT SGLVPPGTPLAHADPSWLTGFRELRGETARLVRGRPVPHSHPYALALARVNELALAAPP FT APRAVPGEDGTLVRELTGPPRCAALLGALARDVVELLTDPVARASLRQCAGDNCPIVYV FT DTSRGRRRRWCSSEVCGNRERVARHRRRVALSR" FT CDS 179219..179782 FT /transl_table=11 FT /gene="SCO2956" FT /gene_synonym="SCE59.15" FT /product="putative integral-membrane protein" FT /note="SCE59.15, possible integral-membrane protein, len: FT 187 aa; similar to TR:CAB66271 (EMBL:AL136519) Streptomyces FT coelicolor putative integral-membrane protein SCC57A.03c, FT 199 aa; fasta scores: opt: 333 z-score: 376.0 E(): 1.6e-13; FT 47.3% identity in 182 aa overlap. Contains possible FT hydrohpobic membrane spanning regions" FT /db_xref="InterPro:IPR018726" FT /db_xref="UniProtKB/TrEMBL:Q9L1T9" FT /protein_id="CAB72202.1" FT /translation="MTDINGERRARAAGGVLVAATVAAGLMAGAFYVFACAVMPALARS FT GDRVYVDVMRDINDVIQNPVFLLVFMGALALAALAGWQSRGLPGSRWIWAGAAAYALAF FT LVTVVGNVPLNDALARPGDPAALRERFEDPWVAWNVVRAVLSTLATACLAAGLTARGRR FT PARSAPRTPQRPTAPHGSPHPTGH" FT CDS complement(180029..180607) FT /transl_table=11 FT /gene="SCO2957" FT /gene_synonym="SCE59.16c" FT /product="hypothetical protein SCE59.16c" FT /note="SCE59.16c, unknown, len: 192 aa" FT /db_xref="UniProtKB/TrEMBL:Q9L1T8" FT /protein_id="CAB72203.1" FT /translation="MDRTRARAVMRGAGRARYGRTASPGPRADRQPAPPTTPRRVPADR FT PSADRPPTGEAPVTPGGRWPVGWGVPWGAVACGAPGRVGGRVSSGPRFREATGVLGARC FT SVLGARCSVLGGRWSVLGARCSVPGGRSGGVCRGAPWRPGRRAVSVVACRRACGSGRLR FT VSSVLGARCSVLGARCSVLGARCPVPGGR" FT CDS complement(180675..181862) FT /transl_table=11 FT /gene="SCO2958" FT /gene_synonym="SCE59.17c" FT /product="putative transcriptional regulator" FT /note="SCE59.17c, possible transcriptional regulator, len: FT 395 aa; similar to TR:P95217 (EMBL:Z86089) Mycobacterium FT tuberculosis hypothetical 40.7 kD protein MCTY0A4.04c, 381 FT aa; fasta scores: opt: 1224 z-score: 1335.3 E(): 0; 52.3% FT identity in 377 aa overlap and C-terminal region similar to FT SW:CUTR_STRCO (EMBL:X58793) Streptomyces coelicolor FT transcriptional regulatory protein CutR, 217 aa; fasta FT scores: opt: 130 z-score: 151.1 E(): 0.53; 30.3% identity FT in 132 aa overlap. Contains Pfam match to entry PF00486 FT trans_reg_C, Transcriptional regulatory protein, C FT terminal" FT /db_xref="GOA:Q9L1T7" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9L1T7" FT /protein_id="CAB72204.1" FT /translation="MDDVSDLSGAGGVGDGARQPGHGPLAGFTVGVTAARRADELGALL FT GRRGATVLHAPALRIVPLADDGELMAATKRIVDRAPDVVVATTAIGFRGWVEAADGWGL FT GDALLERLRTVELLARGPKVKGAVRAAGLTERWSPASESMAEVLDRLLEQGVAGRRIAV FT QLHGEPLPGFVEALREGGAEVVGVPVYRWLPPEDLGPVDRLLDAAVSRGVDAVTFTSAP FT AAVSLLGRAEERGLLPELLAAFGHDVLPACVGPVTAVPLQAHGVDTVQPERFRLGPLVQ FT LLCQELPARARALPVAGHRLEIRGHAVLVDGELRTVPPAGMSLLRALARRPGWVVPRAE FT LLRALPGTGRDEHAVETAMARLRTSLGTPKLIQTVVKRGYRLALDPATDAKYTTD" FT misc_feature complement(180726..180893) FT /note="Pfam match to entry PF00486 trans_reg_C, FT Transcriptional regulatory protein, C terminal, score FT 27.10, E-value 9.9e-07" FT RBS complement(181873..181876) FT CDS complement(181971..183329) FT /transl_table=11 FT /gene="SCO2959" FT /gene_synonym="SCE59.18c" FT /product="putative nitrate extrusion protein" FT /note="SCE59.18c, probable nitrate extrusion protein, len: FT 452 aa; similar to SW:NARK_ECOLI (EMBL:X15996) Escherichia FT coli nitrite extrusion protein 1 (nitrite facilitator 1) FT NarK, 463 aa; fasta scores: opt: 526 z-score: 590.8 E(): FT 1.7e-25; 39.7% identity in 451 aa overlap. Contains FT possible hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9L1T6" FT /db_xref="InterPro:IPR004737" FT /db_xref="UniProtKB/TrEMBL:Q9L1T6" FT /protein_id="CAB72205.1" FT /translation="MKARGGRWIEYWDPENETFWKETGRRTARRNLFFSVLSEHIGFSV FT WTLWSVLVLFMGPEYGLSPADKFLLTSVVTLVGAVVRVPYTFAVAVFGGRNWTVVSASM FT LLVPTLAAFVVMEPGTSFSTFLLVGLLAGIGGGNFASSMTNINAFFPLREKGWALGLNA FT GGGNVGVPVIQLVALAIIGASGGPRVLLGIYIPLILVAAVLAARFMDNLTTVKNDTGAA FT KDAARDAHTWIMSVLYVGTFGSFIGYSFAFGQVLTTQFGRTPLQAAYLTFIGPLLGSLV FT RPLGGRLADRYGGSRITLWNFVAMAAATAVLVVASMERSLALFVTVFVALFVLSGLGNG FT STFKMIPHIFHSKALARGLTGEEAVLHGRRLSGAAMGLIGAVGGLGGVGINLAFRQSFL FT SSGSGTGAFVAFLACYAVCIAVTWSVYLRRPAGRSGTGAGPAAEETRRSYAEV" FT RBS complement(183334..183338) FT CDS complement(183462..184409) FT /transl_table=11 FT /gene="SCO2960" FT /gene_synonym="SCE59.19c" FT /product="putative integral membrane protein" FT /note="SCE59.19c, possible integral membrane protein, len: FT 315 aa. Contains possible hydrophobic membrane spanning FT regions and proline rich C-terminal region" FT /db_xref="UniProtKB/TrEMBL:Q9L1T5" FT /protein_id="CAB72206.1" FT /translation="MSKRQTRKMLELMASGEPVQLTSRMSSVKKLAKLAFVAQQFGYEY FT ADVRQSGGNNAALTMLLVPDPSPQARTRAAQNWAQYPNAGDGVSLPPLVPDAFELLKAR FT INFDLTGKNAQKNMGYGALGGTVACVVIAFREGGSSDDFLISGIIWLVLMAALGIGFLV FT TRKRNAKFAARLQAAGFVPMADETGRVRYLPPGGQLPGHGNPFGAVPGGYGQPAPGQYA FT AQPPQQQPYGGPQQAQQPYAPQPVPQAQPYAAPQAQQPYAPPQTQQPYPPQQPPQPYAQ FT PQQQPYAPPQPQQPYPAQGHPQQNPHWQPRPPQG" FT RBS complement(184417..184420) FT CDS complement(184523..185728) FT /transl_table=11 FT /gene="SCO2961" FT /gene_synonym="SCE59.20c" FT /product="putative integral membrane protein" FT /note="SCE59.20c, possible integral membrane protein, len: FT 401 aa; similar to TR:Q9XAP7 (EMBL:AL078618) Streptomyces FT coelicolor putative integral membrane transferase FT SC10A7.28c, 363 aa; fasta scores: opt: 397 z-score: 390.6 FT E(): 2.4e-14; 46.6% identity in 369 aa overlap. Contains FT possible hydrophobic membrane spanning regions and match to FT Prosite entry PS00038 Myc-type, 'helix-loop-helix' FT dimerization domain signature" FT /db_xref="UniProtKB/TrEMBL:Q9L1T4" FT /protein_id="CAB72207.1" FT /translation="MGTDTDVPVAPQQEQARRAPVRDRYFDLLRAVALFRVVLYHLMGW FT AWLPVVFPSMGVMFALAGNLMARSLKRPAVQVVRSRMRRLLPPLWLLGVVGVTGMVLQG FT WGPSEDGHPGWWWFHLLYWVLPLSDPPFAESVPGIHGILGEDWAAELGGPLWYIRAYLW FT YVLLSPVLLRALRALPWLTILAPLALSAAFQFGYLNLPGERFPSALTDFSTFGACWVLG FT MAHQEGILKRLPRYVVPSVAPVIAALGLWYAFREGFKTGYDLDSIPFAQAVWSFATVLL FT LLHVSPSWTEWPRRLRRWDRLITLLNSRAVTIYLWHNVCILIAATLWDQLWGFEVMYEN FT VPWLLESPWPVLAIAWLLIGSCIVWFGWMEDVAAKRSPQLWPDGGKRTAPKRPRARAAH FT RG" FT misc_feature complement(184784..184831) FT /note="PS00038 Myc-type, 'helix-loop-helix' dimerization FT domain signature" FT CDS complement(185866..188070) FT /transl_table=11 FT /gene="SCO2962" FT /gene_synonym="SCE59.21c" FT /product="putative bi-functional transferase/deacetylase" FT /note="SCE59.21c, possible bi-functional FT transferase/deacetylase, len: 734 aa; similar to TR:Q9XAP6 FT (EMBL:AL078618) Streptomyces coelicolor putative FT bi-functional transferase/deacetylase SC10A7.29c, 743 aa; FT fasta scores: opt: 2045 z-score: 2233.4 E(): 0; 59.5% FT identity in 726 aa overlap and N-terminal region similar to FT SW:NODB_RHIME (EMBL:X01649) Rhizobium meliloti FT chitooligosaccharide deacetylase (EC 3.5.1.-) (nodulation FT protein B) NodB, 217 aa; fasta scores: opt: 411 z-score: FT 455.6 E(): 5.8e-18; 37.9% identity in 198 aa overlap. FT Contains Pfam match to entry PF01522 Polysac_deacet, FT Polysaccharide deacetylase at N-terminal region and Pfam FT match to entry PF00535 Glycos_transf_2, Glycosyl FT transferases at C-terminal region and possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q9L1T3" FT /db_xref="HSSP:1NY1" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q9L1T3" FT /protein_id="CAB72208.1" FT /translation="MASSTRRHGAARSAREGSRRRLPLRLLLPLLVLVALVAMLMLRGY FT VHSEILADHRVQPPAATDKVPQKILEGGPVIDVRGGRTESLSVPDHRLVLTFDDGPDPT FT WTPRVLDVLKKHDAHAVFFVTGTMASRYPDLVERMVDEGHEVGLHTFNHPDLSFQSEKR FT IDWELSQNQLAITGAAGVRTSLFRPPYSSFADAMDNKSWPVTEYIGGRGYLVVVNNTDS FT EDWKKPGVDEIIRRATPKGGKGAIVLMHDSGGDRHQTVQALDRFLPDLKKKGYEFDNLT FT EALDAPGAMSPVTGAELWKGRAWVFLVQASEKLTDGLVVGLAVIGTLVIGRFVLMLLLS FT GVHARRVRRRRFRWGPAVTEPVTVLVPAYNEAKCIENTVRSLVASDHPVEVIVIDDGSS FT DGTARIVEGLGLPGVRVIRQLNAGKPAALNRGLANARYDIVVMMDGDTVFEPSTVRELV FT QPFGDPRVGAVAGNAKVGNKDSLIGAWQHIEYVMGFNLDRRMYDVLGCMPTIPGAVGAF FT RRSALEPIGGMSDDTLAEDTDVTMALHRAGWRVVYAENARAWTEAPESVGQLWSQRYRW FT SYGTMQAIWKHRRAVIEKGPSGRFGRVGLPFVSLFMVLAPLLAPLIDVFLLYGLVFGPT FT EKTIVAWLGVLAIQAVCAAYAFRLDREKLTPLISLPLQQILYRQIMYVVLLQSWITALT FT GGRLRWQKLRRSGGVSAPPPGADGVPPQRRSGAMDGRPVG" FT misc_feature complement(186508..186984) FT /note="Pfam match to entry PF00535 Glycos_transf_2, FT Glycosyl transferases, score 82.10, E-value 1.2e-20" FT misc_feature complement(187348..187803) FT /note="Pfam match to entry PF01522 Polysac_deacet, FT Polysaccharide deacetylase, score 148.60, E-value 1.1e-40" FT CDS complement(188070..189554) FT /transl_table=11 FT /gene="SCO2963" FT /gene_synonym="SCE59.22c" FT /product="putative membrane protein" FT /note="SCE59.22c, putative membrane protein, len: 494 aa. FT Contains C-terminal region rich in proline and glycine. FT Contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9L1T2" FT /protein_id="CAB72209.1" FT /translation="MGAGSADECSESYAHPEVFRGGKCARVKNWQKDAQPEWPEVESGA FT RDLSEAGRDADATEVLPPARAFPPAGGPPMTAPGPGWFGESGESPRGRGSSDADRTQIL FT GSRIGGRAPREQRPDPMAQGRITWGTTDRPGANHGNAAPAPGTGHTPGTGTGPDPDRTD FT VLPSAGPAAPAPPTRAFPAPASAPVPLPVPPPSPGPATAALRDPWQETPDTDGDPGTGT FT GAAGHTHDPHEVTVQLDAVHLGDGVLLRADSGHRKRGPEASDGPVFVDASGRRSRLYRR FT LGILVGIACAVYAVVIVSTLLSGNSDAPWMPVPGQEEGAPAGQVDTTPAPSQSAQPSGT FT GNATTPQATPSADAGVTTEPGVEAPASGTSGVPGGSTGQPGTSAGPESSAAGSGQNPGG FT SGATGPDPTQSTEVPPSTGTDPSAPTGGGAPSGDPTQPTGGSTTDTDPGAGGTNANGAG FT APDPVAGPAGASVVVAEPAAGSSTPPSLPLSPENTL" FT CDS complement(189634..190605) FT /transl_table=11 FT /gene="SCO2964" FT /gene_synonym="SCE59.23c" FT /product="putative lysR-family transcriptional regulator" FT /note="SCE59.23c, probable lysR-family transcriptional FT regulator, len: 323 aa; similar to TR:O88132 FT (EMBL:AJ006517) Streptomyces lipmanii lysR-type FT transcriptional regulator StgR, 327 aa; fasta scores: opt: FT 551 z-score: 619.3 E(): 4.4e-27; 36.6% identity in 320 aa FT overlap and to SW:XAPR_ECOLI (EMBL:X63976) Escherichia coli FT xanthosine operon regulatory protein XapR, 294 aa; fasta FT scores: opt: 364 z-score: 412.4 E(): 1.5e-15; 33.6% FT identity in 301 aa overlap. Contains Pfam match to entry FT PF00126 HTH_1, Bacterial regulatory helix-turn-helix FT protein, lysR family and match to Prosite entry PS00044 FT Bacterial regulatory proteins, lysR family signature. FT Contains possible helix-turn-helix motif at residues 22..43 FT (+3.25 SD)" FT /db_xref="GOA:Q9L1T1" FT /db_xref="HSSP:1IXC" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9L1T1" FT /protein_id="CAB72210.1" FT /translation="MPAPAHLDPRLLRAFVAVAEELHFTRAAARLYVAQQALSRDVRRL FT ERELGAELFVRTTRQVTPTADGERLLPYARRVLQAQDDLLAAFGQARPLLVDLNSPGLA FT TGRLVLERARSLAPEQELMARYESGLTHAAGELVAGRLDASFGRFAGLPAALRAGLGHQ FT PVRHEPMAVVLPEDHPLARLERVPLSALAGETVYAGAGNPRTPEWTDLAHRLFEGRGIH FT VASPVPLAVGEEEFRRIMDKTRNPILAVESFPAMPSTVVRPLVDPVPLSPVSLVWRKGL FT VHPALDALRRAAVQVATENGWLEAPGEGWIPAADAAVMSVHK" FT misc_feature complement(190168..190581) FT /note="Pfam match to entry PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix protein, lysR family, score FT 106.00, E-value 7.1e-28" FT misc_feature complement(190447..190539) FT /note="PS00044 Bacterial regulatory proteins, lysR family FT signature" FT CDS 190884..191984 FT /transl_table=11 FT /gene="SCO2965" FT /gene_synonym="SCE59.24" FT /product="putative transport protein" FT /note="SCE59.24, possible transport protein, len: 366 aa; FT similar to TR:CAB59494 (EMBL:AL132648) Streptomyces FT coelicolor putative transport protein SCI41.24c, 405 aa; FT fasta scores: opt: 513 z-score: 569.7 E(): 2.6e-24; 31.1% FT identity in 366 aa overlap. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9L1T0" FT /protein_id="CAB72211.1" FT /translation="MGMFSVSAVVMIAGTRGSYALAGAVTATGLAATALVAPWTARLVD FT RYGQARVAVPATLFAALGSVALLLCVRHGAPAWTLFAAYAATATTPNTGGMARARWAHL FT LEGDADALHTANSFEQATDELCYMFGPVLAAFLCTALFPEAGTLVGVVLLVTGMLLFTA FT QRATEPPARPRPTAKAPFRAPGIPSLLVVCLAMGGVFGAMEVVTIAFADAQGHRAAAGL FT VLALQAAGSCAAGLLYGAIRPAGPPEHRLPWCVAAMTALLTLPLLAASLGGSLPLLALT FT LLIGGMATAPTMVTTMTLVQHRTPEGRLNEGMTLAVTGLLGGIACGSAAGGWTVEHVSP FT TAAYGIPATAAATALLLTLLPARRTR" FT stem_loop complement(192039..192084) FT misc_RNA complement(192090..192486) FT /note="ssrA gene coding for tmRNA, 397 bp; similar to FT SW:MT10SARNA (EMBL:X60301) Mycobacterium tuberculosis gene FT for 10Sa RNA, 606 bp; blastn scores: Score = 467 (70.1 FT bits), Expect = 8.0e-15, P = 8.0e-15 Identities = 157/220 FT (71%), Positives = 157/220 (71%), Strand = Plus / Plus" FT CDS complement(192600..193079) FT /transl_table=11 FT /gene="SCO2966" FT /gene_synonym="smpB" FT /gene_synonym="SCE59.25c" FT /product="small protein B homologue" FT /note="SCE59.25c, smpB, small protein B homologue, len: 159 FT aa; highly similar to SW:SMPB_ENTFA (EMBL:M90060) FT Enterococcus faecalis small protein B homologue SmpB, 154 FT aa; fasta scores: opt: 559 z-score: 693.2 E(): 3.3e-31; FT 56.1% identity in 155 aa overlap. Contains Pfam match to FT entry PF01668 SmpB, SmpB protein and match to Prosite entry FT PS01317 Protein smpB signature" FT /db_xref="GOA:Q9L1S9" FT /db_xref="HSSP:1P6V" FT /db_xref="InterPro:IPR020081" FT /db_xref="UniProtKB/Swiss-Prot:Q9L1S9" FT /protein_id="CAB72212.1" FT /translation="MAKEKGRKLIAQNKKARHDYQILDTYEAGLVLSGTEVKSLRQGRA FT SLADGFVQLDGHEAWLHNVHVPEYSQGTWTNHSARRKRKLLLHRVEIDKLESKSQETGH FT TIVPLALYFKDGRAKVEIALARGKKEYDKRQTLREKQDRREAERTISAIKRKQRA" FT misc_feature complement(192855..193058) FT /note="Pfam match to entry PF01668 SmpB, SmpB protein, FT score 154.50, E-value 1.8e-42" FT misc_feature complement(192960..192998) FT /note="PS01317 Protein smpB signature" FT CDS complement(193126..194250) FT /transl_table=11 FT /gene="SCO2967" FT /gene_synonym="SCE59.26c" FT /product="putative carboxy-terminal processing protease FT precursor" FT /note="SCE59.26c, probable carboxy-terminal processing FT protease precursor, len: 374 aa; similar to SW:CTPA_BARBA FT (EMBL:L37094) Bartonella bacilliformis carboxy-terminal FT processing protease precursor (C-terminal processing FT protease) CtpA, 434 aa; fasta scores: opt: 505 z-score: FT 527.2 E(): 6e-22; 30.6% identity in 337 aa overlap. FT Contains Pfam match to entry PF00595 PDZ, PDZ domain (Also FT known as DHR or GLGF) and possible N-terminal region signal FT peptide sequence" FT /db_xref="GOA:Q9L1S8" FT /db_xref="HSSP:1G9O" FT /db_xref="InterPro:IPR005151" FT /db_xref="UniProtKB/TrEMBL:Q9L1S8" FT /protein_id="CAB72213.1" FT /translation="MFASVLVAGAASGSLPGTDRKSEPGTARSAAPAGQQARHDDVARA FT AAEAMADGKSPVEAAERAVSRSGDRWGAVYSEGEYEELEDALDGRYTGVGLSARRERDG FT RIEVTRVRSGSPAAGAGIREGDRLRSVDGERVDGRPVTEVVSILRGDGEREPAGTAVRL FT GLERGTRAWTETVRRARLSTDPVTVRTLADGLTVVKVTSFTKGVGEQVREAVARVPSGA FT GVVLDLRGNSGGLVTEAVTAASAFLDGGLVATYDVDGDQRALHAEAGGDTTRPLVALVD FT GGTMSAAELLTGALQDRGRAVVLGSRTFGKGSVQMPSRLPGGSVAELTVGHYRTPSGRG FT VDGTGITPDLEVDPADPGALARARTVLSGLGPTA" FT misc_feature complement(193747..194007) FT /note="Pfam match to entry PF00595 PDZ, PDZ domain (Also FT known as DHR or GLGF)., score 44.70, E-value 2e-09" FT CDS complement(194382..195299) FT /transl_table=11 FT /gene="SCO2968" FT /gene_synonym="SCE59.27c" FT /product="putative cell division protein" FT /note="SCE59.27c, possible cell division protein, len: 305 FT aa; similar to TR:P96293 (EMBL:X70031) Mycobacterium FT tuberculosis FtsX, 297 aa; fasta scores: opt: 591 z-score: FT 681.4 E(): 1.5e-30; 34.9% identity in 304 aa overlap and to FT SW:FTSX_ECOLI (EMBL:X04398) Escherichia coli cell division FT protein FtsX, 352 aa; fasta scores: opt: 194 z-score: 228.3 FT E(): 2.7e-05; 23.4% identity in 295 aa overlap. Contains FT possible N-terminal region signal peptide sequence" FT /db_xref="GOA:Q9L1S7" FT /db_xref="InterPro:IPR003838" FT /db_xref="UniProtKB/TrEMBL:Q9L1S7" FT /protein_id="CAB72214.1" FT /translation="MRAQFVVSEIGVGLRRNLTMTFAVIVSVALSLALFGGSLLMSDQV FT NNMKGYWYDKVNVSVFLCNKSDAESDPNCAKGAVTEDQKKQIMSDLDEMAVVEKVTYES FT QDEAYKHYKEQFGDSPLASSLTPDQMQESYRIKLQDPEKYQVIATAFDGRDGVQSVQDQ FT KGILDNLFGLLNGMNWAARAVMALMLVVALMLIVNTVRVSAFSRRRETGIMRLVGASGF FT YIQAPFIMEAAVAGLIGGGVACGFLVIARYFIIDHGLALSEKLNLINFIGWDAVLTKLP FT LILATSLLMPALAAFFALRKYLKV" FT CDS complement(195343..196032) FT /transl_table=11 FT /gene="SCO2969" FT /gene_synonym="ftsE" FT /gene_synonym="SCE59.28c" FT /product="cell division ATP-binding protein" FT /note="SCE59.28c, ftsE, cell division ATP-binding protein, FT len: 229 aa; similar to TR:O05779 (EMBL:Z95150) FT Mycobacterium tuberculosis FtsE, 229 aa; fasta scores: opt: FT 908 z-score: 1050.8 E(): 0; 62.4% identity in 226 aa FT overlap and to SW:FTSE_ECOLI (EMBL:X04398) Escherichia coli FT cell division ATP-binding protein FtsE, 222 aa; fasta FT scores: opt: 646 z-score: 751.1 E(): 0; 49.1% identity in FT 216 aa overlap . Contains Pfam match to entry PF00005 FT ABC_tran, ABC transporter, two matches to Prosite entry FT PS00017 ATP/GTP-binding site motif A (P-loop) and match to FT Prosite entry PS00211 ABC transporters family signature" FT /db_xref="GOA:Q9L1S6" FT /db_xref="HSSP:1L2T" FT /db_xref="InterPro:IPR005286" FT /db_xref="UniProtKB/TrEMBL:Q9L1S6" FT /protein_id="CAB72215.1" FT /translation="MIRFDNVSKVYPKQSHPALRDVSLEVEKGEFVFLVGSSGSGKSTF FT LRLILREERCSHGQVHVLGKDLARLSNWKVPQMRRQLGTVFQDFRLLPNKTVGENVAFA FT QEVIGKSRGEIRKSVPQVLDLVGLGGKEDRRPGELSGGEQQRVAIARAFVNRPKLLIAD FT EPTGNLDPQTSVGIMKLLDRINRTGTTVVMATHDQNIVDQMRKRVIELEKGRLVRDQAR FT GVYGYQH" FT misc_feature complement(195391..195948) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 229.70, E-value 4.2e-65" FT misc_feature complement(195574..195618) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(195700..195723) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(195904..195927) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 196233..196237 FT CDS 196246..196440 FT /transl_table=11 FT /gene="SCO2970" FT /gene_synonym="SCE59.29" FT /product="putative membrane protein" FT /note="SCE59.29, putative membrane protein, len: 64 aa. FT Contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9L1S5" FT /protein_id="CAB72216.1" FT /translation="MTYDRLVCANCAAPVSEGRCPVCRANRERLQQESNFFAGLNPTTL FT IALLAVLIAAVALLAHQTV" FT CDS complement(196598..197389) FT /transl_table=11 FT /gene="SCO2971" FT /gene_synonym="SCE59.30c" FT /product="putative secreted protein" FT /note="SCE59.30c, possible secreted protein, len: 263 aa. FT Contains the following repeats: 2x(NGGNGNGGNGD) and FT 18x(PDT). Contains also possible N-terminal region signal FT peptide sequence" FT /db_xref="UniProtKB/TrEMBL:Q9L1S4" FT /protein_id="CAB72217.1" FT /translation="MTKKTRIRVARIAAGAVIAAGASLTAAGAASALEIGVSASSEDGL FT NLSVQGGDEDPDPCDIGTGPDCDPTDPTDPTDPTDPTDPTDPTDPTDPTDPTDPTDPTD FT PTDPTDPTDPTDPTDPTDPGNGNNGGNGNNGGAGDNGGNGDNGGSGDNGGNGNGGNGGS FT GDNGGNGNGGNTGGTGGGDNTTPDGGGNDNVAQEEGSSALTDTGEEAQASDTAAQGNGE FT ELAETGAAETTFLLVGAATMIAGGIGFRFLPRLMNGRGAAA" FT repeat_region complement(196859..196897) FT repeat_region complement(196904..196939) FT repeat_region complement(197021..197185) FT /note="18x degenerate repeat translated in SCE59.30c" FT CDS complement(197715..198821) FT /transl_table=11 FT /gene="SCO2972" FT /gene_synonym="prfB" FT /gene_synonym="SCE59.31c" FT /product="chain release factor 2" FT /note="SCE59.31c, prfB, chain release factor 2, len: 368 FT aa; identical to previously sequenced SW:RF2_STRCO FT (EMBL:D86821) Streptomyces coelicolor peptide chain release FT factor 2 (RF-2) PrfB, 368 aa. Contains Pfam match to entry FT PF00472 RF-1, Prokaryotic-type class I peptide chain FT release factors and match to Prosite entry PS00745 FT Prokaryotic-type class I peptide chain release factors FT signature" FT /db_xref="GOA:Q53915" FT /db_xref="HSSP:1GQE" FT /db_xref="InterPro:IPR004374" FT /db_xref="UniProtKB/Swiss-Prot:Q53915" FT /protein_id="CAB72218.1" FT /translation="MAVVDVSEELKSLSSTMESIEAVLDLDRLRADIAVLEEQAAAPSL FT WDDPEAAQKITSKLSHLQAEVRKAEALRGRIDDLGVLFEMAEEEDDPDTRAEAESELAA FT VRKALDEMEVRTLLSGEYDAREALVNIRAEAGGVDAADFAEKLQRMYLRWAEQHGYKTE FT VYETSYAEEAGIKSTTFAVQSPYAYGTLSVEQGTHRLVRISPFDNQGRRQTSFAGVEIL FT PVVEQTDHIEIDESELRVDVYRSSGPGGQGVNTTDSAVRLTHIPTGIVVSCQNERSQIQ FT NKATAMNVLQAKLLERRRQEEQAKMDALKGDGGNSWGNQMRSYVLHPYQMVKDLRTEHE FT VGNPEAVFNGEIDGFLEAGIRWRKQREK" FT misc_feature complement(197715..199601) FT /note="previously sequenced region (EMBL:D86821) S. FT coelicolor" FT misc_feature complement(197814..198416) FT /note="Pfam match to entry PF00472 RF-1, Prokaryotic-type FT class I peptide chain release factors, score 333.10, FT E-value 2.7e-107" FT misc_feature complement(198042..198092) FT /note="PS00745 Prokaryotic-type class I peptide chain FT release factors signature" FT CDS complement(198899..200152) FT /transl_table=11 FT /gene="SCO2973" FT /gene_synonym="pkaB" FT /gene_synonym="SCE59.32c" FT /gene_synonym="SCE50.01c" FT /product="serine/threonine protein kinase" FT /note="SCE59.32c, pkaB, serine/threonine protein kinase FT (partial), len: >233 aa; identical to C-terminal region of FT previously sequenced SW:PKAB_STRCO (EMBL:D86821) FT Streptomyces coelicolor serine/threonine protein kinase FT PkaB, 417 aa. Contains Pfam match to entry PF00069 pkinase, FT Eukaryotic protein kinase domain. Contains possible FT hydrophobic membrane spanning region" FT /note="SCE50.01, pkaB, serine/threonine protein kinase FT (fragment), len: >222 aa; identical to C-terminal region of FT previously sequenced SW:PKAB_STRCO (EMBL:D86821) FT Streptomyces coelicolor serine/threonine protein kinase FT PkaB (EC 2.7.1.-.), 417 aa. Contains Pfam match to entry FT PF00069 pkinase, Eukaryotic protein kinase domain and match FT to Prosite entry PS00108 Serine/Threonine protein kinases FT active-site signature" FT /db_xref="GOA:P54740" FT /db_xref="HSSP:1O6Y" FT /db_xref="InterPro:IPR008271" FT /db_xref="UniProtKB/Swiss-Prot:P54740" FT /protein_id="CAD55460.1" FT /translation="MARKIGSRYTAHQILGRGSAGTVWLGEGPDGPVAIKLLREDLASD FT QELVSRFVQERTALLGLDHPHVVSVRDLVVDGNDLALVMDLVRGTDLRTRLDRERRLAP FT EAAVAVVADVADGLAAAHAAGVVHRDVKPENVLLDMQGPLGPGGSHPALLTDFGVAKLI FT DTPRRTRATKIIGTPDYLAPEIVEGLPPRAAVDIYALATVLYELLAGFTPFGGGHPGAV FT LRRHVTETVVPLPGIPDELWQLLVQCLAKAPASRLRASELSARLRELLPMLAGMAPLDV FT DEPDAEQPEDAPDASAASPAAPVSTAEPVRRRGAVPLVPGAKPADSNRDTHTSMRVPAP FT DELAGGARGTARAPRASGAPRPGSARNRAATRRRRIAVGAGAVALVAAIGVGTWLATGG FT DEDGGGPQDTRNSAPAAP" FT misc_feature complement(199367..199573) FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 28.10, E-value 1.1e-06" FT misc_feature complement(199485..203155) FT /note="previously sequenced fragment EMBL:D86821 FT Streptomyces coelicolor DNA for PkaA, PkaB and PrfB, FT complete cds." FT misc_feature complement(199496..200128) FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 171.00, E-value 1.9e-47" FT misc_feature complement(199739..199777) FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT RBS complement(200158..200162) FT CDS complement(200258..201889) FT /transl_table=11 FT /gene="SCO2974" FT /gene_synonym="pkaA" FT /gene_synonym="SCE50.02c" FT /product="serine/threonine protein kinase" FT /note="SCE50.02c, pkaA, serine/threonine protein kinase, FT len: 543 aa; identical to previously sequenced FT SW:PKAA_STRCO (EMBL:D86821) Streptomyces coelicolor FT serine/threonine protein kinase PkaA (EC 2.7.1.-), 543 aa. FT Contains Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain and match to Prosite entry PS00108 FT Serine/Threonine protein kinases active-site signature" FT /db_xref="GOA:P54739" FT /db_xref="HSSP:1O6Y" FT /db_xref="InterPro:IPR002290" FT /db_xref="UniProtKB/Swiss-Prot:P54739" FT /protein_id="CAB87324.1" FT /translation="MRPVGSKYLLEEPLGRGATGTVWRARQRETAGAEAAVAGQPGETV FT AIKVLKEELASDADIVMRFLRERSVLLRLTHPNIVRVRDLVVEGELLALVMDLIDGPDL FT HRYLRENGPLTPVAAALLTAQIADALAASHADGVVHRDLKPANVLLKQTGGEMHPMLTD FT FGIARLADSPGLTRTHEFVGTPAYVAPESAEGRPQTSAVDVYGAGILLYELVTGRPPFG FT GGSALEVLHQHLSAEPRRPSTVPDPLWTVIERCLRKNPDDRPSAENLARGLRVVAEGIG FT VHANSAQIGAAENVGALLAPDPAPAQVPGAPDAAYDPNGATSVLPHTSGPAGAADPTAV FT LPSTGAPDPTAVMPPVPPGQPGAPGQGGPEDPHPWQNQLRAARDRNEQTQVQYLDPNQD FT PLRRRPQRQVSRPPQQPRQAPQGPPPQQPGYGYPQQQQPQRYATPQPQQPQRYAPPPAP FT EPQQPRREPRPPRQRSANPMRIPGLGCLKGCLVTVVVLFVAGWLVWELSPLQEWIGTGK FT GYWDQLTDWFTTVTDWIGDLGGSGGG" FT misc_feature complement(201083..201868) FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 248.80, E-value 7.3e-71" FT misc_feature complement(201440..201478) FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT RBS complement(201898..201902) FT CDS 202287..206324 FT /transl_table=11 FT /gene="SCO2975" FT /gene_synonym="SCE50.03" FT /product="hypothetical protein SCE50.03" FT /note="SCE50.03, unknown, len: 1345 aa. High G+C content FT (80.71%) and high also in alanine, glycine and proline FT amino acid residues" FT /db_xref="GOA:Q9L060" FT /db_xref="InterPro:IPR002543" FT /db_xref="UniProtKB/TrEMBL:Q9L060" FT /protein_id="CAB87325.1" FT /translation="MQIRLTVVDPLGPHASAASAVPATDRPARCDVLVTAPAGTALAAV FT ASALAATLPGEGPGSGQVVLYAGAQRLDAQRSTLGEPPLIDGAVLCLGAPGEPDPHTEP FT AEVPAQLHVVAGPDAGGVHLLHGGQIRLGRSADADVALDDPDVSRMHCAVTVGPDARVS FT VADLGSTNGTTLDGTRVGDRPVRFPPGALLRIGESALRLVPVPPTAQERVATTPDGEGH FT VRLTGPGAPSSEDGDGGAVVHARAADGAEGQVRDADGRSRATGPGRHGPADGPARQAGP FT SGFSRVADPDGRADGRGSVAADGAAPDPAPRGTGPDGTVRPRGRTHHAYGTSGYDRGAA FT PAEPPQVPGQGGAPRIESRGTGSSAGLPRQSPTGGETHGGARGAGAYATGGSGAGGPGA FT PAPRTAGRGAPGRDPYAEGPPAPGAARTGAGDPHSDGPGPGAYGAPAPGTPGSDPHGRD FT AYDRDAYERDPGGRDASYGQSLSGPDRTGPEPADAGALRGDPSGAGDSRPSTTGATAHR FT PADTPGGADGAGPDTRTGRGGAPGARTARKGTPLRGTDMPQEVRRRGGIGAWARRLTGG FT RGGAPEAPAPGGFASGGAAAGPAPASPPGTSGAPETWPDPASLLLTALGPGPRLWERGP FT GHPEALTVRLGTADRVAPGGDAPLPAVPVTAGLREVGALGLAGPRERLTGLARSVLAQL FT AALHSADTLEIVLISADRSRPLAERTAEWSWLGWLPQVRPGHGQDCRLLLAHDREQATA FT RAAELLRRLDDHLGDEARPGARPLDTAEDTPAAAAAAGTVRPQPSWARPDDGADPAGGF FT TGPYTVVVVDGDPGGADVREAVARLALEGPRAGVHVVCLAETAAASPTSPVTRTYEAAC FT AVSPVFRECGAVALLSGDVATTLRLLRVARTGPNPGTGAPAAPAGPVGHGTLCTVDAVS FT LPWAERFARALAPLRTDSAADGGEHHARVSAPLPRTARLLDELGLARATPASLMARWAA FT AADDTESLGGRAQAVLGAGPRGPVLADLAAEGPHLLIEGPAGSGRTELLRAFVASLASA FT ERPDRLGVVLMDGRDSVSSGGARGEGLHVCTDVPHVTTHLTANDPVRMREFAQSLSAEL FT KRRAELLGRSDFAEWHTGREVSGRLVSQRGPAAAGPAPVSDSGDVESPPSSTLRLRPAA FT ARRRTGPVPPLPRLVVVVDDLDALVTPPLGSPGRPAAGSVMRALEAVAREGERLGVHLV FT AATAPDGRTDRTEPALRATLRVTLDPPVPGPDEPAPGRGRLARPDGRTTAFQGGRVTGR FT IPRTATLRPTVVPLEWHRMGDPPARRPVRELGNGPTDLALLASALERAAREVSAAEVPS FT LL" FT CDS complement(206365..206994) FT /transl_table=11 FT /gene="SCO2976" FT /gene_synonym="SCE50.04c" FT /product="hypothetical protein SCE50.04c" FT /note="SCE50.04c, unknown, len: 209 aa" FT /db_xref="UniProtKB/TrEMBL:Q9L059" FT /protein_id="CAB87326.1" FT /translation="MGSNDELYEKSVLDVPKLQRYARKVAKAAHSKVPMASHQEYVVRQ FT HQEVRRKGWFSKESVTVSERCAQGPALRYWELGRVADETFRRKDGADLYGHVHINWTGV FT DDGSMIILLEDGELRHVAYSVRDTGPHYPVLEMETSHTEWKVAAMRPHDYLLLDRPNLG FT RMREKTYSRKSGLLYMEELRRNYRVTVRQKGLGLSLALNRLLKRAE" FT RBS complement(206999..207003) FT CDS 207082..208281 FT /transl_table=11 FT /gene="SCO2977" FT /gene_synonym="SCE50.05" FT /product="hypothetical protein SCE50.05" FT /note="SCE50.05, unknown, len: 399 aa" FT /db_xref="UniProtKB/TrEMBL:Q9L058" FT /protein_id="CAB87327.1" FT /translation="MPYAPVESAVLQRNDRERRAPGSGSRVPGRMQHCAMMRIMLCGAA FT DTERVRDAFVQVVEDFGGIPRHFLSGTVNYINSATSSWTENSRESVQDADICVFVIVEE FT IGRITWETEVSEALMSGKPFLVLCLDKTHQRYLFLHSTFPPPTDLSVIPSEQDRNLVMT FT LRELYHERQITVAPFTDGSFRDVLRRELSQLFRIAVGHLSERNRRGSAVPLFAQPSRLS FT MTDLVIARRIALDEFEEKHKRKQALRALAARRALDEEPLYALLNSPEQGIQRLSFELLE FT QLYTPRPAAPAFLEHLVVIANDSDDVGVPRRMIPIVMAIDLAGAVAALALLDLDDAGCK FT RRLAACLEAHEDAVAELGLGEPVAELLRACLSGSAPSDWKSRCRAYLDRLGGAPSEGAG FT " FT CDS 208475..209872 FT /transl_table=11 FT /gene="SCO2978" FT /gene_synonym="SCE50.06" FT /product="putative secreted protein" FT /note="SCE50.06, possible secreted protein, len: 465 aa; FT similar to TR:Q55471 (EMBL:D64006) Synechocystis sp. FT hypothetical 46.5 kD protein, 421 aa; fasta scores: opt: FT 788 z-score: 803.7 E(): 0; 35.2% identity in 386 aa FT overlap, to C-terminal part of SW:MSME_STRMU (EMBL:M77351) FT Streptococcus mutans multiple sugar binding protein FT precursor MsmE, 420 aa; fasta scores: opt: 240 z-score: FT 249.6 E(): 1.9e-06; 25.7% identity in 303 aa overlap and to FT SW:AGLE_RHIME (EMBL:AF045609) Rhizobium meliloti FT (Sinorhizobium meliloti) alpha-glucosidase-binding FT periplasmic protein AglE precursor, 429 aa; fasta scores: FT opt: 503 Z-score: 522.9 E(): 1.7e-21; 35.452% identity in FT 409 aa overlap. Contains Pfam match to entry PF01547 FT SBP_bacterial_1, Bacterial extracellular solute-binding FT protein and correctly situated match to Prosite entry FT PS00013 Prokaryotic membrane lipoprotein lipid attachment FT site. Contains also possible N-terminal region signal FT peptide sequence" FT /db_xref="GOA:Q9L057" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:Q9L057" FT /protein_id="CAB87328.1" FT /translation="MRTSSTIRTRGTVKRTTRAAAALAAGALALSLTACGGDEDNGGGD FT GGDEGGGAKQPASSVTLPKLDGESLEVAAVWTGTEQENFKKVLAEFEKRTGAKVTFVPA FT QDPIINFLGSKIAGGAPPDVAMLPQPGAIKQAVDKGWAKPLGAEATKELGENYSQGWQD FT IGKVGGKQYGVYYKAANKSLIWYNAQVFENAGAAEPKTWDELLNAAQMVYDSGVTPFSV FT GGADGWTLTDWFENVYLSQAGPEKYDQLAKHEIKWTDPSVKDALTTLAEIWGKKDFVAG FT GASGALQTEFPASVTQTFTGGDQPKAGMVYEGDFVQVNIGETKAKVGTDAKVFPFPAVG FT DTAPVVSGGDAAVVFKDSKAAQALATWLASPDAAGIQAKLGGFLSPNKSIDSSVYPNEV FT QKKIAEALVAAGDDFRFDMSDQAPQAFGGTPGKGEWKTLQDFLKNPKDVAGAQAKLEAD FT AAAAYGG" FT misc_feature 208547..208579 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature 208976..209854 FT /note="Pfam match to entry PF01547 SBP_bacterial_1, FT Bacterial extracellular solute-binding protein, score FT 68.70, E-value 2.8e-18" FT CDS 209949..211232 FT /transl_table=11 FT /gene="SCO2979" FT /gene_synonym="SCE50.07" FT /product="putative integral membrane transport protein" FT /note="SCE50.07, possible integral membrane transport FT protein, len: 427 aa; N-terminal and C-terminal regions FT both similar to TR:Q55472 (EMBL:D64006) Synechocystis sp. FT membrane bound sugar transport protein, 279 aa; fasta FT scores: opt: 307 z-score: 333.7 E(): 3.8e-11; 26.5% FT identity in 412 aa overlap. Contains Pfam match in FT C-terminal region to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component and match also in C-terminal region to Prosite FT entry PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign. Contains possible N-terminal FT region signal peptide sequence and also possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9L056" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9L056" FT /protein_id="CAB87329.1" FT /translation="MTGTRRSVAALFLLPALVLLGALVVYPIGYSLIRSFYDQSGDSFA FT GFDNYETLFTDDGIRTALKNNVIWVVFAPTVATALGLIFAVLTERIRWGTAFKLVVFMP FT MAISMLAAGIIFRLVYDQDPDKGVANAVWVGVHDTFAESSAFPKAHPGRDSPLKPAGGG FT AFITKQPVGAGTPVALPLVGVAPDLMPDGAKKAATAEPADGKVTGTTWQDFTRGKGVGR FT LGGVDAAELGYAGMKIEAVKDGEVVATTTAAGDGTFTLPAAADGALLRLPADNFKEAYN FT GLNWLGPSLVTPAIIGSYVWMWAGFAMVLIAAGLAGMPRELLEAARVDGANEWQVFRRV FT TVPLLAPVLAVVVVTLMINVLKVFDLVFIIAPGSSQDDANVLALELYRKGFASDQPGVA FT SAIAVFLLLLVIPVMWFNVRRLRREVRR" FT misc_feature 210888..211112 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 55.50, E-value 1.2e-12" FT misc_feature 210891..210977 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT RBS 211217..211221 FT CDS 211229..212146 FT /transl_table=11 FT /gene="SCO2980" FT /gene_synonym="SCE50.08" FT /product="putative integral membrane transport protein" FT /note="SCE50.08, possible integral membrane transport FT protein, len: 305 aa; similar to TR:Q55473 (EMBL:D64006) FT Synechocystis sp. membrane bound sugar transport protein, FT 298 aa; fasta scores: opt: 883 z-score: 1001.8 E(): 0; FT 44.5% identity in 272 aa overlap. Contains Pfam match to FT entry PF00528 BPD_transp, Binding-protein-dependent FT transport systems inner membrane component and match to FT Prosite entry PS00402 Binding-protein-dependent transport FT systems inner membrane comp sign. Contains also possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9L055" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9L055" FT /protein_id="CAB87330.1" FT /translation="MTADAGSLTPAATRPPETAVKARQPLASRLAEAAGGGLVRVFLIV FT VGLFWLVPTIGLLLSSLRTPEDMAASGWWKVLTEPSQLTFQSYEELLKNGDITSSLLNT FT ALITVPATVLVVVIGALAGYAFAWMEFPGRDWWFLAVVGLLVVPVQVALIPIAELFGKI FT GLFGSMLGVILFHVGFGLPFAVFLLRNFFAEIPRELLEAARLDGAGELRLFVRVVMPLG FT GPAIASLGIFQFLWVWNDMLVALIFSDSGNQPITVALQTQVRQFGNNIDVLAPGAFISM FT VIPLAVFFAFQRQFVSGVMAGAVK" FT misc_feature 211799..212020 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 50.10, E-value 5e-11" FT misc_feature 211802..211888 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT stem_loop 212165..212199 FT /note="12681 TGAGGGGGCGGGCCGGT 12697 12699 FT ACCGGCCCGCCCCCTCA 12715. Score 51: 17/17 (100%) matches, 0 FT gaps" FT CDS 212299..214596 FT /transl_table=11 FT /gene="SCO2981" FT /gene_synonym="SCE50.09" FT /product="putative glycosyl transferase" FT /note="SCE50.09, possible glycosyl transferase, len: 765 FT aa; similar to TR:CAB66267 (EMBL:AL136518) Streptomyces FT coelicolor putative glycosyl transferase (fragment) FT SCC123.27, 743 aa; fasta scores: opt: 2334 z-score: 2578.7 FT E():0; 50.4% identity in 748 aa overlap and to FT SW:TAGF_BACSU (EMBL:X15200) Bacillus subtilis teichoic acid FT biosynthesis protein F, TagF, 746 aa; fasta scores: opt: FT 319 z-score: 350.8 E(): 4.3e-12; 27.9% identity in 376 aa FT overlap. Also similar to Streptomyces coelicolor SCE50.10, FT 736 aa; fasta scores: opt: 1837 z-score: 1644.2 E(): 0; FT 45.2% identity in 756 aa overlap and SCE50.11, 745 aa FT ;fasta scores: opt: 2095 z-score: 1875.1 E(): 0; 49.0% FT identity in 764 aa overlap. Contains Pfam match to entry FT PF00535 Glycos_transf_2, Glycosyl transferases" FT /db_xref="GOA:Q9L054" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q9L054" FT /protein_id="CAB87331.1" FT /translation="MEVPVPRFSVIVPAYQVQAYLHACLESVLAQSYPDFEVIVVDDGS FT PDACGTIADEFAALDPRVRVIGLPRNEGLGPARNAGMERAGGDYLVFLDGDDTLTPHAL FT RGIADRIKETGEPDVLVYDYARTYWTGETVRNQAAAHLTEQGPAPFRLADRPGLLKLLM FT VAWNKAVRREFAVREGFAFPPGYYEDTPWTYPVLMTAGSVATLDRVCVHYRQRLRGSIL FT GTPGERHLDVFTQYDRVFAFLDARMETHPESRKELARWRPLLYRRMADHLTTVYTRPGR FT LPRSLRAEFLRRARVHCRRYRVPGAPAPLPVRLRHALLRLGLRRTYGALRLASALRRGT FT AGVAAGLLRAARTGALRLHYRVQRCLPLRADRAVFAVEGDRGYGRDPGALEEAFRRLAP FT HVRTAWTADRVHHHTVPPGTRRLTPGTAAHWTALARSRYLVREGAFGPGLVRRRGQVLV FT QTQAGTPLKHMGLDLQERPAAAQGTDFARLLREADSWDYVVSANRHSTLTWERVHPGDW FT TALEYGQPRTDVLQRATAADVARLRETLGVPEGTVAILYAPTHRDYRRTQRSALDLERV FT VRRLGPRFVVLARAHPRHGGPLAASAGRVLDVSDHPHVESLCLASDALVTDYSSLMFDY FT AGLDRPIVIHAAEREAYEAARGTYVDLRSFPPGAIARDEDELIGVFASGDWHGTRSARL FT RAAFRERFCPYDDGRAAERVVRRVVLGETDPPPAVPLSGRRPAPSATAALARTPLTTVP FT PPAGPRTVTDSL" FT misc_feature 212323..212838 FT /note="Pfam match to entry PF00535 Glycos_transf_2, FT Glycosyl transferases, score 93.50, E-value 4.1e-24" FT CDS 214616..216826 FT /transl_table=11 FT /gene="SCO2982" FT /gene_synonym="SCE50.10" FT /product="putative glycosyl transferase" FT /note="SCE50.10, possible glycosyl transferase, len: 736 FT aa; similar to TR:CAB66267 (EMBL:AL136518) Streptomyces FT coelicolor putative glycosyl transferase (fragment) FT SCC123.27, 743 aa; fasta scores: opt: 2115 z-score: 2498.8 FT E():0; 47.9% identity in 746 aa overlap and to FT SW:TAGF_BACSU (EMBL:X15200) Bacillus subtilis teichoic acid FT biosynthesis protein F, TagF, 746 aa; fasta scores: opt: FT 465 z-score: 545.7 E(): 6e-23; 30.9% identity in 376 aa FT overlap. Also similar to Streptomyces coelicolor SCE50.09, FT 765 aa; fasta scores: opt: 1837 z-score: 1731.8 E(): 0; FT 44.8% identity in 754 aa overlap and SCE50.11, 745 aa; FT fasta scores: opt: 1407 z-score: 1326.5 E(): 0; 43.7% FT identity in 746 aa overlap. Contains Pfam match to entry FT PF00535 Glycos_transf_2, Glycosyl transferases" FT /db_xref="GOA:Q9L053" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q9L053" FT /protein_id="CAB87332.1" FT /translation="MPRFSIIVPSHGVAGRLSQALDSVLGQSFGDFELIPVCDGPDCAA FT ADVAGEHAERDSRVTPVHSPPSAGLAGARNAGMRAATGAYLLFLDGDDTFVPGALAALD FT ARLADTGGVDVLYFEHERVPWWEGETTNPAAPLLAKTPDGAFAPDRAPHLTGVDLPAWS FT AVHRRTFLTERRLDFPGGHFTDVGFGARVAARAERMAVLREVVVRHRVRRQGNRLNLPG FT EHHADLLDQAELALTHAVERGLPPERRGPLFEQLFAAVLKTATHPRRLTRRGRRAFYRR FT ASRLYRRHRPAGFRPPGGRLGVQHRLLASGSYTAFRALRAANRTATGVLRRLPWPRGLR FT TRLRYRRHLRRPLDPNLVVYCAYWGRGYACNPAAIHAKARELAPHLRSVFLVEPDQAHT FT LPEGVDHAVVGSHRYWEVLARATYLVNNANFAEGVVKRPGSVHLQTQHGTPLKTMGVDQ FT STYPVVAAATGSFTKLLARVDRWDFNLSANRHSTQMWERAFPGSYEHLEYGYPRNDVYC FT TATAGDVARVRRELGVPEGKTAVLYAPTHRDWETGFGAGGLDLEAFCEAAGEDVVVLLR FT AHYFYDRGGSRERTGRVIDVTGHRSSEDVCLAADALVTDYSSIMFDYANLDRPIVVYAD FT DWDVYRETRGVYFDLMAAPPGPVARTPEELARVFADGSWAGPESTALRAAFRERFCEFD FT DGRAAERVVRRVLLGEPPEALPPVLPLAERVPAPAAATLVRS" FT misc_feature 214628..215248 FT /note="Pfam match to entry PF00535 Glycos_transf_2, FT Glycosyl transferases, score 25.80, E-value 0.001" FT RBS 216817..216822 FT CDS 216834..219071 FT /transl_table=11 FT /gene="SCO2983" FT /gene_synonym="SCE50.11" FT /product="putative glycosyl transferase" FT /note="SCE50.11, possible glycosyl transferase, len: 745 FT aa; similar to TR:CAB66267 (EMBL:AL136518) Streptomyces FT coelicolor putative glycosyl transferase (fragment) FT SCC123.27, 743 aa; fasta scores: opt: 2355 z-score: 2721.3 FT E(): 0; 51.2% identity in 732 aa overla and to FT SW:TAGF_BACSU (EMBL:X15200) Bacillus subtilis teichoic acid FT biosynthesis protein F, TagF, 746 aa; fasta scores: opt: FT 553 z-score: 636.4 E(): 5.3e-28; 28.2% identity in 432 aa FT overlap. Also similar to Streptomyces coelicolor SCE50.09, FT 765 aa; fasta scores: opt: 2095 z-score: 1969.9 E(): 0; FT 48.7% identity in 764 aa overlap and SCE50.10, 736 aa; FT fasta scores: opt: 1407 z-score: 1323.0 E(): 0; 43.7% FT identity in 746 aa overlap. Contains Pfam match to entry FT PF00535 Glycos_transf_2, Glycosyl transferases" FT /db_xref="GOA:Q9L052" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q9L052" FT /protein_id="CAB87333.1" FT /translation="MPRFSVIVPCFKVQGFLRQCLDSVLDQSFRDIEVIAVDDCSPDGS FT GAILDEYAARDDRVRVLHLEENAGLGRARNAGLPLATGDYLFFLDSDDTLTPGALRAMA FT DRLAETDGPDVLVFDYARTYWWGGTRRNVLARVLAQAGDGTFTAAGHPEILDLLMVVWN FT KVYRRDFVEREGFTFPPGYYEDTPWTFPVMFSAERIAALDRICLNYRQRRQGNILSTTS FT RKHFDVHAQYERVFAFLDARPELAARWRPFLHAKMGEHCLDILSKPDRLPPSDRAEFFH FT RTTEMFRAHRPEGAAVPAGLRVLEGSYAAYRVRRQSGRAARELERRTRPALAAAAGRLR FT RTASTVHVRRPLDPDLVVYSAFSHRGVLGDPAAIHRAARELAPHLRGVWVVRDEESAAD FT PALLPPGTEHVVLGSAAYRRVTERAAFFVNNVNWPGTVAKRPGTVHLHTHQGTPLKHMG FT VDLLDRPGARHGLDVPQMLRRADRWDHSLVASRYAERVWERAYPCHFTSARTGSPRNDA FT LVNAGPEDGRRVRERLGVPAGHTVVLYAPTRREYRRGGLVERLDVARLAADLGEGHTLL FT VRLHPSLATGPARGLGLTELHRRGVVVDATDEPHVEDLMLASDLLITDYSALMFDYALL FT DRPILIHAEDWGPYSATRGTYFDITEEAPGHVSRSYRELAWLLASGAWRDEEAARLRGS FT FRARYCEYEDGRAAERVVRTLLLGEPMPAPEPSGVPGARAVPSGRDLLPST" FT misc_feature 216846..217334 FT /note="Pfam match to entry PF00535 Glycos_transf_2, FT Glycosyl transferases, score 87.90, E-value 2.1e-22" FT CDS 219068..220399 FT /transl_table=11 FT /gene="SCO2984" FT /gene_synonym="SCE50.12" FT /product="putative integral membrane protein" FT /note="SCE50.12, possible integral membrane protein, len: FT 443 aa. Contains possible hydrophobic membrane spanning FT regions and possible N-terminal region signal peptide FT sequence" FT /db_xref="UniProtKB/TrEMBL:Q9L051" FT /protein_id="CAB87334.1" FT /translation="MRPRSRVDGRGAVVGVLLLAAVFAVLQLANVTGRDTPDTRNYLSY FT ALSLTGEGKRAAATATIDYVCASRAERARRGQSVHVVRFHRPDPTGAVLAECREQEWAV FT VRPRLAAGQTGGHTVPYMSERFMAIFEARPGYPAFLVPFVLAFGVTWGLWTAGVVIAGA FT GGVLVFLILRTLSVPVPLALAGQALYYVLPCGTTAMRPMTEGLLMALTLAAVWGCALVL FT RAGRNRAGLAVVAGSLIALFTVKHSQALFLGLCLAAAGGVIALRRHRRRARRLRGRGGP FT ASRDVLALAAVGLAGALATVLLARLLHYPSEADSLQDLLTDHFNRPDRKHPWPEFWQLQ FT GNFWVEWLRRQAWQPMFVAALAAGAWGALRRGGAVGGFLVAAACTGLLTQAGHPDINIW FT GERLIVLAWLLPVVGVPLLLEPVVRGGRVPLPAQEQRDRAGAIG" FT CDS 220539..222092 FT /transl_table=11 FT /gene="SCO2985" FT /gene_synonym="SCE50.13" FT /product="putative integral membrane protein" FT /note="SCE50.13 possible integral membrane protein, len: FT 517 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9L050" FT /protein_id="CAB87335.1" FT /translation="MSADVLVRRPVRGATALRGGRAWRPTPYQVAGFLFFLVMTLAYWA FT VPLCCDAGQHAAVVERLKADLLHPRHPMADLPGEGSAYYSPYAVAQGVFARLTGLGGWE FT VVRLAGPLNLLVLLTGLNRFVRVLTPRPWAPVLALGAMALLWGTERAWWSGYLGLMSMT FT GNLGYPSAFAIGLTFWAWALTGARARDGRRVRYVGPSGLRGLPGYGALGVLYGLILLVH FT PITSVAAVLGAVALVAGWQGGWRGPVVGRWALTGAVAVGAAAAWPYFDVFALAGDDSVD FT AMHRVLYLDLPGEFWLALLGLPALWARGRRSRRDPLVLMFALDCAVVAYGWFSGHYTYG FT RILGLTLVPPQFALAVELAAPRPWGRWRAVLGRAAAAGALLGFLAVHAGAVVPRALDPV FT GFEQPPDWPAYTWAARHIGPGEVVITDGYYAGHAIAGYGPNLAAPAWPDPALDERERGR FT RAADVKAYLAPGSTRAERAAVVRRYHVRWLLLTRWHPVPEEAVVVAWSERTGEVLARVG FT " FT CDS complement(222114..222527) FT /transl_table=11 FT /gene="SCO2986" FT /gene_synonym="SCE50.14c" FT /product="conserved hypothetical protein SCE50.14c" FT /note="SCE50.14c, hypothetical protein, len: 137 aa; FT similar to TR:CAB62728 (EMBL:AL133423) Streptomyces FT coelicolor hypothetical 14.2 kD protein SC4A7.24c, 139 aa; FT fasta scores: opt: 533 z-score: 620.7 E(): 4e-27; 60.9% FT identity in 133 aa overlap" FT /db_xref="GOA:Q9L049" FT /db_xref="HSSP:1N2F" FT /db_xref="InterPro:IPR019953" FT /db_xref="UniProtKB/TrEMBL:Q9L049" FT /protein_id="CAB87336.1" FT /translation="MDALYTAAATATHGRDGRAVSSDGTLDLALGIPVEMGGNGQGTNP FT EQLFAAGYAACFGSALGVVGRAAKVDVSDAAVTAEVGIGKQGEGFALAVTLRVELPEGL FT DEETGRKLVEQAHQVCPYSNATRGNIPVDLVIE" FT RBS 222659..222662 FT CDS 222666..223172 FT /transl_table=11 FT /gene="SCO2987" FT /gene_synonym="SCE50.15" FT /product="putative regulatory protein" FT /note="SCE50.15, possible regulatory protein, len: 168 aa; FT similar to SW:HPCR_ECOLI (EMBL:S56952) Escherichia coli FT homoprotocatechuate degradative operon repressor HpcR, 148 FT aa; fasta scores: opt: 151 z-score: 195.2 E(): 0.002; 27.9% FT identity in 136 aa overlap. Contains Pfam match to entry FT PF01047 MarR, MarR family" FT /db_xref="GOA:Q9L048" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9L048" FT /protein_id="CAB87337.1" FT /translation="MTTPATEPAAEPAAEPATDWLRLDQQICFSLSAASRAFGSVYRVV FT LKDLGLTYSQYLVLLVLWEHGELPVKRLGEHLRLDSGTLSPLLKRLEAAGLVRRERSTR FT DERSVQVRLTEEGAALRGRAVEVPRRIAAATGLDLAEVQDLRARLDRLTAALDAYGTAP FT APEPS" FT misc_feature 222816..223121 FT /note="Pfam match to entry PF01047 MarR, MarR family, score FT 96.20, E-value 6.6e-25" FT CDS 223250..224230 FT /transl_table=11 FT /gene="SCO2988" FT /gene_synonym="galE2" FT /gene_synonym="SCE50.16" FT /product="UDP-glucose 4-epimerase" FT /note="SCE50.16, galE2, UDP-glucose 4-epimerase, len: 326 FT aa; highly similar to SW:EXOB_AZOBR (EMBL:Z25478) FT Azospirillum brasilense UDP-glucose 4-epimerase (EC FT 5.1.3.2) ExoB, 348 aa; fasta scores: opt: 885 z-score: FT 970.7 E(): 0; 46.4% identity in 319 aa overlap and to FT SW:GALE_STRLI (EMBL:M18953) Streptomyces lividans FT UDP-glucose 4-epimerase (EC 5.1.3.2) GalE, 329 aa; fasta FT scores: opt: 793 z-score: 870.9 E(): 0;42.7% identity in FT 328 aa overlap. Contains Pfam match to entry PF01370 FT Epimerase, NAD dependent epimerase/dehydratase family" FT /db_xref="GOA:Q9L047" FT /db_xref="HSSP:1GY8" FT /db_xref="InterPro:IPR005886" FT /db_xref="UniProtKB/TrEMBL:Q9L047" FT /protein_id="CAB87338.1" FT /translation="MTWLITGGAGYIGAHVVRAMTEAGEKAVVYDDLSTGIAERVPDGV FT PLVVGSVLDGERVARALADHSVTGVVHLAAKKQVGESVDLPLHYYRQNVEGLRVLLDAV FT TAAGVPSFVFSSSAAVYGMPDVDLVTEETPCVPMSPYGETKLAGEWLVRATGRATGLAT FT ASLRYFNVAGAASPDLVDTGVYNLVPMVFEKLTESAAPRIFGDDYATPDGTCVRDYIHV FT VDLAEAHVAAARALQSSPGTALTLNIGRGEGVSVREMIDRINAVTGCDQPPTVTPRRPG FT DPARVVASADRAAVELGWKAKYDVEDMITSAWAGWVRLHPEAARD" FT misc_feature 223256..224212 FT /note="Pfam match to entry PF01370 Epimerase, NAD dependent FT epimerase/dehydratase family, score 363.30, E-value FT 2.5e-105" FT CDS complement(224243..224680) FT /transl_table=11 FT /gene="SCO2989" FT /gene_synonym="SCE50.17c" FT /product="putative integral membrane protein" FT /note="SCE50.17c, possible integral membrane protein, len: FT 145 aa; similar to TR:Q9X8C2 (EMBL:AL049763) Streptomyces FT coelicolor hypothetical 13.0 kD protein SCE36.09, 114 aa; FT fasta scores: opt: 256 z-score: 321.6 E(): 1.8e-10; 53.5% FT identity in 71 aa overlap. Contains possible N-terminal FT region signal peptide sequence and possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q9L046" FT /db_xref="InterPro:IPR002109" FT /db_xref="UniProtKB/TrEMBL:Q9L046" FT /protein_id="CAB87339.1" FT /translation="MRRAWTGPVLLLIAGAGAATGPIVQGRPGTGAVLSVVFVLLAGLT FT SPLVFPRSVGALEARRRSAADGRPVVFWRPGCTYCLRLRLRLGRRARRLHWVDIWRDEA FT GAEAVREVNDGNETVPTLLVAGRAYTNPDPAWVREQVSSTR" FT CDS complement(224677..225288) FT /transl_table=11 FT /gene="SCO2990" FT /gene_synonym="SCE50.18c" FT /product="conserved hypothetical protein SCE50.18c" FT /note="SCE50.18c, hypothetical protein, len: 203 aa; FT similar to TR:Q9Z552 (EMBL:AL03521) Streptomyces coelicolor FT hypothetical 17.8 kD protein, 162 aa; fasta scores: opt: FT 203 z-score: 257.9 E(): 6.4e-07; 29.7% identity in 165 aa FT overlap and to TR:Q9AK06 (EMBL:AL512944) Streptomyces FT coelicolor hypothetical protein SC8D11.13, 194 aa; fasta FT scores: opt: 588 Z-score: 704.3 E(): 1.4e-31; 49.735% FT identity in 189 aa overlap" FT /db_xref="InterPro:IPR007061" FT /db_xref="UniProtKB/TrEMBL:Q9L045" FT /protein_id="CAB87340.1" FT /translation="MTPTDPKADLRLYLQSARDALLWKLEGLSEYDVRRPATPTGTNLL FT GLVKHAATVELGYLGDTFGRPSGEPLPWLADGAEPNADMWVTADESRAYVVELYHRAWA FT HADATIDALALDTVGRVPWWGEGKDEVTLHHAVTRVIADTHRHAGHADIVRELTDGAVG FT MREDNAGVPAADTAWWEAYRDRVEHAAREAGHRGTPGRAR" FT CDS complement(225285..226088) FT /transl_table=11 FT /gene="SCO2991" FT /gene_synonym="SCE50.19c" FT /product="hypothetical protein SCE50.19c" FT /note="SCE50.19c, unknown, len: 267 aa" FT /db_xref="UniProtKB/TrEMBL:Q9L044" FT /protein_id="CAB87341.1" FT /translation="MGGMAVTDRPSISTLTLEHRIPQDWTADPWAEVRPLIDGVDVLGE FT VHPEGMAPSCRGWRGPGESWPLAVTAVPRRVLISEPTCTVGCCGGLYVTMRREGGRVIW FT DAWENTSDINAVPTEVHFDAAQYEAELARAAADRGWEEPVDTVARLLEQILVDSGGFER FT WSCVLTGVRPRREEPDEPEELALPEGVDVEFSASPAPGTPACSYRYELPLVPDRSPREQ FT ARRLAARILADDPRRSAERGDQRVASDPSPRCVPVPRTGGGRLAP" FT RBS complement(225297..225300) FT CDS complement(226104..226598) FT /transl_table=11 FT /gene="SCO2992" FT /gene_synonym="SCE50.20c" FT /product="putative acetyltransferase" FT /note="SCE50.20c, probable acetyltransferase, len: 164 aa; FT similar to TR:O66161 (EMBL:AB005901) Streptomyces FT kasugaensis kasugamycin acetyltransferase KAC338, 141 aa; FT fasta scores: opt: 756 z-score: 933.2 E(): 0; 76.8% FT identity in 142 aa overlap. Contains Pfam match to entry FT PF00583 Acetyltransf, Acetyltransferase (GNAT) family" FT /db_xref="GOA:Q9L043" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9L043" FT /protein_id="CAB87342.1" FT /translation="MAGAGCARIRFLPGPGVRPAPDPSASGSAYDRTVTITYRWRGDVD FT NVLLGALHADGFGHPPDGTDWRTQLERHSLGWVCAWENGSLVGFVNVAWDGGAHAFLLD FT TVVARHCRSRGVGAQLVAVAAEQARAAACEWLHVDFEDDLRPFYLDACGFKETSAGLIA FT L" FT misc_feature complement(226134..226493) FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 19.00, E-value FT 0.016" FT CDS 226597..227151 FT /transl_table=11 FT /gene="SCO2993" FT /gene_synonym="SCE50.21" FT /product="hypothetical protein SCE50.21" FT /note="SCE50.21, unknown, len: 184 aa" FT /db_xref="UniProtKB/TrEMBL:Q9L042" FT /protein_id="CAB87343.1" FT /translation="MTHTAGMDQEAGAYDLLLIGGGSGVGKSTVGREVSALLRAAGTAH FT CLIEGDGMDQIHPAPEGDPHRTGITERNIAAVWANYAALGQRRLLYTNTVSILEAPMIG FT RAMGGDEVRVTCVLLTADEATVRQRLAVRETGSQLGIHIERSLRMARRLAEEAPVGTVR FT VPTDGRAVRDIAAQVVRLAGW" FT CDS complement(<227199..>227889) FT /transl_table=11 FT /gene="SCO2994" FT /gene_synonym="SCE99.01c" FT /product="putative tetR-family transcriptional regulator FT (fragment)" FT /note="SCE99.01c, probable tetR-family transcriptional FT regulator (fragment), len: >230 aa; similar to TR:Q54288 FT (EMBL:X86780) Streptomyces hygroscopicus regulator of FT antibiotic transport complexes ORFY, 204 aa; fasta scores: FT opt: 427 z-score: 493.1 E(): 6.3e-20; 45.5% identity in 167 FT aa overlap. Contains Pfam match to entry PF00440 tetR, FT Bacterial regulatory proteins, tetR family and a possible FT helix-turn-helix motif at residues 71..92 (+4.56 SD)" FT /db_xref="GOA:Q9EWI0" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9EWI0" FT /protein_id="CAC18731.4" FT /translation="VSVGRGNAGTQPFRRDALCLTRMTTNAAADEPTPRPRRRAPAGAA FT VLREDVTEAIRAAVFEELAAVGYARMSIEGIARRAGVGKTAVYRRWRSKLHLVLDIVSA FT LAVQGLPAPDTGSLEGDLRLLYEVTSRALRHPVASQIIPDLQAEAARNADIAEALQKTL FT REGQDGVASKILAAAAERGELAPGLDTDLALDLISGPLYWRSVVVRGPKPPKGYLGSLA FT RATAEGLK" FT misc_feature complement(227587..227727) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 45.50, E-value FT 3.9e-10" FT CDS 227996..228952 FT /transl_table=11 FT /gene="SCO2995" FT /gene_synonym="SCE99.02" FT /product="putative ABC transporter integral membrane FT protein" FT /note="SCE99.02, possible ABC transporter integral membrane FT protein, len: 318 aa; similar to TR:Q9X7V2 (EMBL:AL049485) FT Streptomyces coelicolor putative ABC transporter membrane FT component SC6A5.06, 309 aa; fasta scores: opt: 1393 FT z-score: 1546.8 E(): 0; 69.0% identity in 300 aa overlap FT and to SW:RFA1_KLEPN (EMBL:L31775) Klebsiella pneumoniae FT O-antigen export system permease protein RfbA, 259 aa; FT fasta scores: opt: 327 z-score: 370.8 E(): 4.1e-13; 26.6% FT identity in 199 aa overlap. Contains Pfam match to entry FT PF01061 ABC2_membrane, ABC-2 type transporter and possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9EWH9" FT /db_xref="InterPro:IPR013525" FT /db_xref="UniProtKB/TrEMBL:Q9EWH9" FT /protein_id="CAC18732.1" FT /translation="MSQVLDPPPPTRASTQAAPFTTESGPAAGSDLAALAARHGLTVSG FT ARPSLPQYVRDLWARRHFIGAFSTAKLTAQYSQAKLGQLWQVMTPLLNAAVYYFIFGLL FT MDTKRGVEDFVPFLVTGVFVWTFTQSSIMAGTRAISGNLGLVRALHFPRAALPVSFCLQ FT QLQQLLFSMAALLVILLAFGVPPAPSWVLALPALVLQFLFNAGVAMVMARVGSKIPDMA FT QLMPFLLRTWMYASGVMFSIEHMTGPDSGLPSWVGTALQLNPAVVYIDLMRFALIDTFG FT GSQLPPHVWALAVGWALVAGIGGFVYFWKAEETYGRG" FT misc_feature 228155..228943 FT /note="Pfam match to entry PF01061 ABC2_membrane, ABC-2 FT type transporter, score 149.70, E-value 5.2e-41" FT CDS 228990..229856 FT /transl_table=11 FT /gene="SCO2996" FT /gene_synonym="SCE99.03" FT /product="putative ABC transporter ATP-binding protein" FT /note="SCE99.03, possible ABC transporter ATP-binding FT protein, len: 288 aa; similar to SW:RFB1_KLEPN FT (EMBL:L31775) Klebsiella pneumoniae O-antigen export system FT ATP-binding protein RfbB, 246 aa; fasta scores: opt: 550 FT z-score: 504.2 E(): 1.5e-20; 40.2% identity in 209 aa FT overlap and to TR:Q9X7V3 (EMBL:AL049085) Streptomyces FT coelicolor putative ABC transporter ATP-binding component FT SC6A5.07, 253 aa; fasta scores: opt: 1381 z-score: 963.7 FT E(): 0; 82.5% identity in 251 aa overlap. Contains Pfam FT match to entry PF00005 ABC_tran, ABC transporter and match FT to Prosite entry PS00017 ATP/GTP-binding site motif A FT (P-loop) and PS00211 ABC transporters family signature" FT /db_xref="GOA:Q9EWH8" FT /db_xref="InterPro:IPR017871" FT /db_xref="UniProtKB/TrEMBL:Q9EWH8" FT /protein_id="CAC18733.1" FT /translation="MPTVVVDGVDIVYRVNGTGAGRGTATAALNRILRRGKTEKAAGVR FT RVHAVKKVSFVAYRGEAIGLIGTNGSGKSTLLKAVAGLLPVEHGRIYTDGQPSLLGVNA FT ALMNDLTGERNVYLGGLAMGMSRAQVKERYQEIVDFSGINEKGDFITLPMRTYSSGMAA FT RLRFSIAAAKDHDVLLVDEALATGDRSFQKRSEQRIRELRKHAGTVFLVSHSNKSIRDT FT CDRVLWLERGELRVDGPTEEVLKEYEKFTAGPGPAAKPKPQAKAAPAPAPASAPAPAPA FT PKAPTAV" FT misc_feature 229167..229685 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 116.40, E-value 5.2e-31" FT misc_feature 229188..229211 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 229458..229502 FT /note="PS00211 ABC transporters family signature" FT misc_feature 229749..229850 FT /note="High G+C content region (84.31%). Also high content FT in alanine ad proline amino acid residues" FT RBS 229971..229976 FT CDS 229985..232225 FT /transl_table=11 FT /gene="SCO2997" FT /gene_synonym="SCE99.04" FT /product="putative transferase" FT /note="SCE99.04, possible transferase, len: 746 aa; similar FT to TR:Q9L053 (EMBL:AL163672) Streptomyces coelicolor FT putative glycosyl transferase SCE50.10, 736 aa; fasta FT scores: opt: 1826 z-score: 2036.2 E(): 0; 46.9% identity in FT 749 aa overlap" FT /db_xref="GOA:Q9EWH7" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q9EWH7" FT /protein_id="CAC18734.1" FT /translation="MSVTAMSETAPDLSVIVHGRNVQDHLPALLDSLDAHPLTGVEVIV FT AAVGDWAREVAERHAPAFTVLPLPDGAGDAAARSAGAARARGRWLHFVHAKDGLPVGAP FT PAVAERAGALPDAVEVLLLDHVRSSWRASGLPSPDGPRLARAGRAGESLALDDRAGLLR FT LTPLLGNRAVRAGFWRAHERLLTTEDEPFAAYAALLLADRVACLPHPAYEDRRLRPESL FT PPPTAAQRYALVDRYEALLGLTADRPAVHGVLYDLMIRDCLHTFARAGMPDDVAREFFH FT RASVTARRHRPEGLRRPAGLEGVRRSLLEEGAYGRYRALRTASHARRGVRAAARTGRRR FT AGTRLRTLQYRAALARPLDPHLAVFSAYWNRGVACNPAAIAAKLAELAPGVHPVWVVTA FT QGAALLPPGTDHVVPGTRRYWEVLARAKYLVNNVNFPDAVVKRPGTVHLQTHHGTPLKR FT MGVDQLPYPAAAHGLDFQALLERVDKWDFSVSANSHSTRMWQRAYPSRHLSLDHGYPRN FT DVYYTAGPAEVRAARERLGIAPGRRAVLYAPTHRDYEAGWTPRLDLAALADRLGEETVL FT LMRAHYFYDSAAAPSAPLAGLRRTGRLVDVSSYEPVEELCLAADALVTDYSSIMFDYAN FT LDRPIVIHADDWETYRTTRGVYFDLMAEAPGPVARTQAELTEILTSDAWHDERAAKART FT AFRRRFCEYDDGRAAERVVRRVFLGEDERTLPPVLPVEDRTPAPSPEEATSS" FT misc_feature 230195..230248 FT /note="High G+C content (88.88%). Also high content in FT alanine, arginine and glycine amino acid residues" FT RBS 232206..232211 FT CDS 232222..233943 FT /transl_table=11 FT /gene="SCO2998" FT /gene_synonym="SCE99.05" FT /product="putative transferase" FT /note="SCE99.05, possible transferase, len: 573 aa; FT N-terminal domain similar to TR:AAG01876 (EMBL:AF292031) FT Mesorhizobium huakuii glucosyltransferase Exo1, 340 aa; FT fasta scores: opt: 312 z-score: 366.8 E(): 6.8e-13; 30.3% FT identity in 337 aa overlap. Contains Pfam match to entry FT PF00535 Glycos_transf_2, Glycosyl transferases" FT /db_xref="GOA:Q9EWH6" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q9EWH6" FT /protein_id="CAC18735.1" FT /translation="MRTATSTSPATGTPAPVPSRTPDVTVTVIVYNDAGRLPRAVASAL FT RQSHANIEVVISDDHSTDATEEVARELAAHDPRVVYLRLPENSGGCSAPRNRALEIARA FT PYLMFLDSDDELPERAVEVLLAAHRERDLDFAMGAVHRIREDGGRRTTWMPHLVAERRT FT LDGIEADPRLLFEHLSTSKMYARAFLDRHGLRFPEGIHYEDQLFSAQAYCLAKTFTVVP FT EPVYRWYIAPYADADSASISNQRHKLTNVRDRVHVQRLIDAFLAESGHEALREDKDFKF FT LKHDFRMYAGDLPYRDDTWLASFADLMNPYLDTLAEGAYARLPRAERVVLRLLRDRRLS FT DVRTAARGLGHDVAPRRVTPDEQSGRVYWGEEVPASPESRRELDLTDLDLDTRPFFTAL FT LRHEITEITRGPGASVDLTVRTYDPALRLPVGPQRAVLHLSPGPRRLTVPFRLSPVRPG FT LFEGRVRLDLAAARLPLHGFAGTRHPVLRLRHRGRTHTGILLAPLAFPPLTARVPYRTG FT LTPHRVTLRPEGHNPGRLQITWQPVGTTAKILGPAARRLSTPRTRRAARLLSNILR" FT misc_feature 232294..232800 FT /note="Pfam match to entry PF00535 Glycos_transf_2, FT Glycosyl transferases, score 109.10, E-value 8.5e-29" FT CDS complement(234161..239122) FT /transl_table=11 FT /gene="SCO2999" FT /gene_synonym="SCE33.01c" FT /gene_synonym="SCE99.06c" FT /product="conserved hypothetical protein" FT /note="SCE33.01c, hypothetical protein (fragment), len: FT >187 aa; similar to TR:Q9X7B2 (EMBL:AL049913) Mycobacterium FT leprae hypothetical 177.9 kD protein MCLB1610.10, 1622 aa; FT fasta scores: opt: 154 z-score: 172.5 E(): 0.038; 29.7% FT identity in 155 aa overlap" FT /note="SCE99.06c, conserved hypothetical protein FT (fragment), len: >1515 aa; similar to TR:AAG06456 FT (EMBL:AE004731) Pseudomonas aeruginosa conserved FT hypothetical protein PA3068, 1620 aa; fasta scores: opt: FT 4170 z-score: 4589.7 E(): 0; 46.3% identity in 1521 aa FT overlap" FT /db_xref="GOA:Q8CJY0" FT /db_xref="InterPro:IPR007780" FT /db_xref="UniProtKB/TrEMBL:Q8CJY0" FT /protein_id="CAD55461.1" FT /translation="MQTKLDEAKAELLERAARVAENSPVGGHLPTGTTGEGTPGTPDGP FT DGAPDYASVFAFLQRYYRHTAPEDLADRDPVDIFGAAVSHYRLAENRPQGTANVRVHTP FT TVEENGWTCSHSVVEVVTDDMPFLVDSVTNELTRQGRGIHVVVHPQIVVRRDIAGKLVE FT VLAGPPAADLPHDAHVESWIHVEIDRETDRGDLKQITADLLRVLNDVRETVEDWGKMRD FT AAVRIADQLSTEATPEDLPARELEEARELLRWLADDHFTFLGYREYQLREDDSLAAVAG FT TGLGILRSDPHHAADESHPVSPSFERLPADARAKAREHRLLVLTKANSRATVHRPSYLD FT YVGVKKFDENGNVVGERRFLGLFSSAAYTESVRRVPVVRRKVEEVLERAGFSPNSHDGR FT DLLQILETYPRDEMFQTSVEELEPIVTSVLYLQERRRLRLYLRQDEYGRYYSALVYLPR FT DRYTTGVRLRIIDILKEELGGTSVDFTAWNTESILSRLHFVVRVPQGTELPHLSDADKE FT RVEARLVEAARSWADGFGEALTAEFGEERAAELLRLYGSAFPEGYKADHGPRSAVADLG FT HLEQLDEETTFALSLYEPVGAAPEERRFKIYQKGGSVSLSAVLPVLSRLGVEVTDERPY FT ELRCADRTTAWIYDFGLRMPKAPSGGADYLGDDARERVQDAFAATWTGKAENDGFNALV FT LSAGLTWREAMVLRAYAKYLRQAGSTFSQDYMEDTLRNNVHTTRLLINLFEARMAPERQ FT RAGREIVDALLEEVDAALDQVASLDEDRILRSFLTVIKATLRTNFFQEASGGVPHDYVS FT MKFDPQAIPDLPAPRPAFEIWVYSPRVEGVHLRFGKVARGGLRWSDRREDFRTEILGLV FT KAQMVKNTVIVPVGAKGGFVAKQLPDPGVDRDAWLAEGIASYKTFISALLDITDNMVAG FT EVVHPADVVRHDEDDTYLVVAADKGTAKFSDIANEVAESYNFWLGDAFASGGSAGYDHK FT GMGITARGAWESVKRHFRELGVDTQTQDFTVVGIGDMSGDVFGNGMLLSEHIRLVAAFD FT HRHIFIDPTPDAATSYAERRRLFELPRSSWEDYNTELLSAGGGIFPRTAKSIPVNAHVR FT EALGIEPGVTKMTPAELMKAILSSPVDLLWNGGIGTYVKASTESNADVGDKGNDAIRVD FT GKDLRVQVVGEGGNLGLTQLGRIEFALQGGRINTDAIDNSAGVDTSDHEVNIKILLNGL FT VKDGDMTVKQRNKLLAQMTDEVGALVLRNNYAQNTAIANALAQSRDMLHAQQRFMRHLV FT REGHLNRALEFLPTDRQIRERLSSGHGLTGPETAVLLAYTKITVAEELLHTSLPDDPYL FT KGLLHAYFPTALREQFAEQVDGHPLRREITTTVLVNDTVNTGGTTYLHRMREETGASLE FT EIVRAQTVARAIFRSSPVWDAVEELDTKADAAVQTRIRLHSRRLVERGTRWLLNNRPQP FT LELAETVDFFAERVEQVWSQLPKLLRGADAEWYQHIYDELTGAGVPDEPATLVAGFSSV FT FAALDIVSVADRMGKEPLDVAEVYYDLADRLGVTQLMDRISDLPRDDRWQSMARAAIRE FT DLYAAHAALTADVLAVGNGSSTPEQRFKAWEEKNAAILGRARTTLEEIRQSDAFDLSNL FT SVAMRTMRTLLRTHS" FT RBS complement(239125..239129) FT CDS complement(239625..240296) FT /transl_table=11 FT /gene="SCO3000" FT /gene_synonym="SCE33.02c" FT /product="putative phosphatase" FT /note="SCE33.02c, possible phosphatase, len: 223 aa; FT similar to TR:AAF42165 (EMBL:AE002532) Neisseria FT meningitidis phosphoglycolate phosphatase, putative FT NMB1830, 219 aa; fasta scores: opt: 221 z-score: 270.1 E(): FT 1.4e-07; 28.4% identity in 218 aa overlap and to FT SW:GPH_RHOCA (EMBL:U23145) Rhodobacter capsulatus FT phosphoglycolate phosphatase (EC 3.1.3.18) CbbZ, 219 aa; FT fasta scores: opt: 158 z-score: 196.2 E(): 0.0018; 25.4% FT identity in 189 aa overlap. Contains Pfam match to entry FT PF00702 Hydrolase, haloacid dehalogenase-like hydrolase" FT /db_xref="GOA:Q9KYY0" FT /db_xref="InterPro:IPR006439" FT /db_xref="UniProtKB/TrEMBL:Q9KYY0" FT /protein_id="CAB90911.1" FT /translation="MGMQTGAHIVWDWNGTLFHDNDAIIGATNAAFAELGLAPITLERY FT RALYCVPVPKFYERLMGRLPTNAEWEVMDATFQRYYSVHRSRCTLADGATELLVRWRSA FT GRSQSILSMYGHDELVPLVRGLGIETHFIRVDGRMGPSGGSKAEHMVRHLAQLALSGVE FT PARTVVIGDAADDAVAASHAGAGAVLYTGGSHSRASLEGVGVPVVDTLGEAVAVAERLA FT G" FT misc_feature complement(239718..240281) FT /note="Pfam match to entry PF00702 Hydrolase, haloacid FT dehalogenase-like hydrolase, score 18.60, E-value 0.00019" FT CDS complement(240355..240858) FT /transl_table=11 FT /gene="SCO3001" FT /gene_synonym="SCE33.03c" FT /product="conserved hypothetical protein SCE33.03c" FT /note="SCE33.03c, hypothetical protein, len: 167 aa; FT similar to TR:O0587 (EMBL:Z95121) Mycobacterium FT tuberculosis hypothetical 17.8 kD protein MTCY20B11.06c, FT 169 aa; fasta scores: opt: 415 z-score: 473.1 E(): 6.8e-19; FT 49.1% identity in 171 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9KYX9" FT /protein_id="CAB90912.1" FT /translation="MRVYVPLTLSGLAEAHRAGELGTGPLVAYAVTPALREWYLSDDIE FT ELEYAALNRAALASLRLLAADPAGVRRRVVVAADVPDGAAVADPDRGLDPAALGEVRLA FT GPLPLAKAAAVHVDSADAEADVRAAVEALAAADGGDDDAQYVVDGAEDHELLWYATQEL FT PNLV" FT CDS complement(240837..241124) FT /transl_table=11 FT /gene="SCO3002" FT /gene_synonym="SCE33.04c" FT /product="hypothetical protein SCE33.04c" FT /note="SCE33.04c, unknown, len: 95 aa" FT /db_xref="UniProtKB/TrEMBL:Q9KYX8" FT /protein_id="CAB90913.1" FT /translation="MILYGVEGRRGKDVGGRVEGVGRFTYQSDAGERRGRARGVGRVNS FT GTGVDVSEVTGGDSKGDTRTYPEGSSAGPPSAPAASPTTKAADSCASTSP" FT CDS complement(241149..241496) FT /transl_table=11 FT /gene="SCO3003" FT /gene_synonym="SCE33.05c" FT /product="hypothetical protein SCE33.05c" FT /note="SCE33.05c, unknown, len: 115 aa. High content in FT glycine and proline amino acid residues and also high % G+C FT (80.57%)" FT /db_xref="UniProtKB/TrEMBL:Q9KYX7" FT /protein_id="CAB90914.1" FT /translation="MPPGPVDGTPPGPPDTWRSLPPGLRSGAPPVPPGGVADELYDGVA FT PGPYDGEADGPYDGEADGPYDGEAPGAEEGVAPGPPWGGGGEVGGDAGAVGRGWVRVMT FT LRMGVPVRRPG" FT CDS 242029..242298 FT /transl_table=11 FT /gene="SCO3004" FT /gene_synonym="SCE33.06" FT /product="hypothetical protein SCE33.06" FT /note="SCE33.06, unknown, len: 89 aa. High content in FT arginine amino acid residues and also high % G+C (77.4%)" FT /db_xref="UniProtKB/TrEMBL:Q9KYX6" FT /protein_id="CAB90915.1" FT /translation="MLRHTVGRAYDDLAHLAERGPLRTRGTSPVVRDIGYFEPRPGALE FT VFARIGAGDRLRAMAFRLERGRDLRWRCTAVEVGGPRRTRADDD" FT CDS complement(242427..245270) FT /transl_table=11 FT /gene="SCO3005" FT /gene_synonym="secA" FT /gene_synonym="SCE33.07c" FT /product="preprotein translocase" FT /note="SCE33.07c, secA, preprotein translocase, len: 947 FT aa; identical to SW:SECA_STRLI (EMBL:U21192) Streptomyces FT lividans preprotein translocase SecA subunit, 947 aa. FT Contains Pfam match to entry PF01043 SecA_protein, SecA FT protein, amino terminal region and match to Prosite entry FT PS01312 Protein secA signatures" FT /db_xref="GOA:P0A4G6" FT /db_xref="HSSP:1NKT" FT /db_xref="InterPro:IPR011116" FT /db_xref="UniProtKB/Swiss-Prot:P0A4G6" FT /protein_id="CAB90916.1" FT /translation="MSVLSKLMRAGEGKILRKLHRIADQVNSIEEDFADLSDAELRALT FT DEYKQRYADGESLDDLLPEAFATVREAAKRVLGQRHYDVQIMGGAALHMGYVAEMKTGE FT GKTLVGTLPAYLNALSGEGVHIVTVNDYLAERDSELMGRVHKFLGLNVGCILANQTPAQ FT RREMYACDITYGTNNEFGFDYLRDNMAWSKDELVQRGHNFAIVDEVDSILVDEARTPLI FT ISGPADQATKWYGDFAKLVTRLKKGEAGNTLKGIEETGDYEVDEKKRTVAIHESGVAKV FT EDWLGIDNLYESVNTPLVGYLNNAIKAKELFKKDKDYVVLDGEVMIVDEHTGRILAGRR FT YNEGMHQAIEAKEGVDIKDENQTLATITLQNFFRLYKRHDHDGKEQPGLSGMTGTAMTE FT AAEFHQIYKLGVVPIPTNRPMVRKDQSDLIYRTEVAKFEAVVDDIEEKHRKGQPILVGT FT TSVEKSEYLSQQLSKRGVQHEVLNAKQHDREATIVAQAGRKGSVTVATNMAGRGTDIKL FT GGNPEDLAEAELRQRGLDPEEHIEEWAAALPAALERAEQAVKAEFEEVKELGGLYVLGT FT ERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDDLMRLFKAQMVERVMSMANVPDDVPI FT ENKMVTRAIASAQSQVETQNFETRKNVLKYDEVLNRQREVIYGERRRVLEGEDLQEQIQ FT HFTNDTIDAYVQAETAEGFPEDWDLDRLWGAFKQLYPVKVTVEELEEAAGDRAGLTADY FT IAESIKDDVREQYEAREKQLGSEIMRELERRVVLSVLDRKWREHLYEMDYLQEGIGLRA FT MAQKDPLVEYQREGFDMFQAMMDGIKEESVGYLFNLEVQVEQQVEEVPVEDAAPSLDKG FT AQDAVPAQAGARPEIRAKGLDAPQRRDLHFSAPTVDGEGGVVEGEFTDGEPAQAQSDGL FT TRAERRKQAKGGRRRKK" FT misc_feature complement(243720..243767) FT /note="PS01312 Protein secA signatures" FT misc_feature complement(243951..245261) FT /note="Pfam match to entry PF01043 SecA_protein, SecA FT protein, amino terminal region, score 1076.90, E-value 0" FT RBS complement(245280..245285) FT CDS 245552..246127 FT /transl_table=11 FT /gene="SCO3006" FT /gene_synonym="SCE33.08" FT /product="putative acetyltransferase" FT /note="SCE33.08, possible acetyltransferase, len: 191 aa; FT similar to TR:Q9Z576 (EMBL:AL035569) Streptomyces FT coelicolor putative acetyltransferase SC8D9.15, 194 aa; FT fasta scores: opt: 212 z-score: 283.0 E(): 2.6e-08; 40.5% FT identity in 84 aa overlap. Contains possible hydrophobic FT membrane spanning region" FT /db_xref="GOA:Q9KYX5" FT /db_xref="HSSP:1NSL" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9KYX5" FT /protein_id="CAB90917.1" FT /translation="MEPVTLTTDRLVLRTVGPRDAEAVHAACQDPDIQRWTMVPSPYLP FT EHARGFTEQMVPDGWANDSMFTFGLFLPAGDLVGMLGVTMISLGVGEIGFWGTKEHRGR FT GYITEAAVAAARWAFTERAVDRLEWRAEVGNAASRAVAQRAGFAMEGTLRSAINNKGVR FT RDCWVGSLLPCDLALPSTSPYLPTPGAA" FT CDS 246212..247387 FT /transl_table=11 FT /gene="SCO3007" FT /gene_synonym="SCE33.09" FT /product="conserved hypothetical protein SCE33.09" FT /note="SCE33.09, hypothetical protein, len: 391 aa; similar FT to TR:AAF11622 (EMBL:AE002043) Deinococcus radiodurans FT conserved hypothetical protein DR2072, 360 aa; fasta FT scores: opt: 300 z-score: 355.4 E(): 2.5e-12; 30.1% FT identity in 362 aa overlap and to TR:Q9HZZ9 (EMBL:AE004711) FT Pseudomonas aeruginosa hypothetical protein PA2844, 402 aa; FT fasta scores: opt: 629 Z-score: 729.7 E(): 5.2e-33; 40.415% FT identity in 386 aa overlap" FT /db_xref="InterPro:IPR009351" FT /db_xref="UniProtKB/TrEMBL:Q9KYX4" FT /protein_id="CAB90918.1" FT /translation="MTTLPPPATELSADEARRLALRAQGFLGAPDRRAGVRGVLRHLGA FT VQLDTISVLARSHELIPYARLGAVGRRTVDDAYWTDTHAFEYWSHAACILPIEEWPHFA FT FRRRAYRNRPHWNHHLPEGDYDRVVKQLREEGPLTATDLGGAKRTSEWWDWSGTKVAVE FT RALMYGEVVCVERRGWKRVYDLAERAVPAALLHDDLDDTECLRRLVRLAGQSLGVGTRA FT DIADYHRLKAEQVDAVIADSGLVPVTVAGWGRPAWADPAALETVPRGRHRTTLLSPFDS FT LIWERARTERIFGFTHRLEAYVPRQKRVHGYFAMPVLAGGRLVGRVDPAREGRTLVAKQ FT VTLDGPKAAPAVAQALVEAAGWVDCTNVRVERVETPDLREPLARELARLLD" FT CDS complement(247422..248180) FT /transl_table=11 FT /gene="SCO3008" FT /gene_synonym="SCE33.10c" FT /product="putative two-component system response regulator" FT /note="SCE33.10c, probable two-component system response FT regulator, len: 252 aa; similar to TR:AAF10563 FT (EMBL:AE001951) Deinococcus radiodurans DNA-binding FT response regulator DR0987, 239 aa; fasta scores: opt: 576 FT z-score: 658.2 E(): 3.3e-29; 44.0% identity in 218 aa FT overlap and to various Streptomyces coelicolor putative FT two-component response regulators, e.g. TR:CAB59507 FT (EMBL:AL132648) SCI41.37, 223 aa; fasta scores: opt: 622 FT z-score: 571.0 E(): 2.8e-26; 47.2% identity in 214 aa FT overlap. Contains Pfam matches to entries PF00072 FT response_reg, Response regulator receiver domain and FT PF00196 GerE, Bacterial regulatory proteins, luxR family, FT and match to Prosite entry PS00622 Bacterial regulatory FT proteins, luxR family signature. Contains also possible FT helix-turn-helix motif at residues 204..225 (+5.13 SD)" FT /db_xref="GOA:Q9KYX3" FT /db_xref="HSSP:1A04" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9KYX3" FT /protein_id="CAB90919.1" FT /translation="MADSFGPMRGAGVDHGIDDGVAGMGPDAGSAREEPIRVLVVDDHA FT LFRRGLEIVLAAEEDIQVVGEAGDGAEAVEKAADLLPDIVLMDVRMPKRGGIEACTSIK FT EVAPSAKIIMLTISDEEADLYDAIKAGATGYLLKEISTDEVATAIRAVADGQSQISPSM FT ASKLLTEFKSMIQRTDERRLVPAPRLTDRELEVLKLVATGMNNRDIAKELFISENTVKN FT HVRNILEKLQLHSRMEAVVYAMREKILEIR" FT misc_feature complement(247428..247625) FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 104.30, E-value FT 2.3e-27" FT misc_feature complement(247491..247574) FT /note="PS00622 Bacterial regulatory proteins, luxR family FT signature" FT misc_feature complement(247734..248075) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 131.20, E-value 1.9e-35" FT RBS complement(248184..248189) FT CDS complement(248409..249173) FT /transl_table=11 FT /gene="SCO3009" FT /gene_synonym="SCE33.11c" FT /product="conserved hypothetical protein" FT /note="SCE33.11c, hypothetical protein, len: 254 aa; FT similar to TR:O05886 (EMBL:Z95121) Mycobacterium FT tuberculosis hypothetical 24.5 kD protein MTCY20B11.16c, FT 214 aa; fasta scores: opt: 487 z-score: 551.0 E(): 3.1e-23; FT 47.6% identity in 210 aa overlap" FT /db_xref="GOA:Q9KYX2" FT /db_xref="InterPro:IPR003489" FT /db_xref="UniProtKB/TrEMBL:Q9KYX2" FT /protein_id="CAB90920.1" FT /translation="MDRNLVQKGDAPPSKRSDPGTEFCVDIVVKGRKTEVPERFRKHVA FT EKLKLEKIQKLDGKVISLDVEVSKEPNPRQADRCDRVEITLRSRGPVIRAEAAASDPYA FT ALDLAAEKLGARLRKQHDKRFSRRGARRISAAEVADHVPGAATLNGNGDVVPTEKQDGV FT PTKKIGSLEVQGDGPLVVREKTHVAAPMSLDQALYEMELVGHDFYLFVDSETKEPSVVY FT RRHAYDYGVIHLTTDTMVTQAHAPDAGDALGG" FT RBS complement(249181..249184) FT CDS complement(249415..250362) FT /transl_table=11 FT /gene="SCO3010" FT /gene_synonym="SCE33.12c" FT /product="hypothetical protein SCE33.12c" FT /note="SCE33.12c, hypothetical protein, len: 315 aa; FT similar to TR:O05887 (EMBL:Z95121) hypothetical 22.5 kD FT protein MTCY20B11.17c, 213 aa; fasta scores: opt: 189 FT z-score: 191.8 E(): 0.0032; 36.8% identity in 228 aa FT overlap" FT /db_xref="InterPro:IPR002375" FT /db_xref="UniProtKB/TrEMBL:Q9KYX1" FT /protein_id="CAB90921.1" FT /translation="MRGLRTCLTRRTWRRGWADLTDLVLPAECGGCGTARAVLCPRCRT FT ALSGAPPCRVRPEPEPPGLPAVHAAAPYADEVRAALLAHKERGVLALTAPLGVALAQAV FT RAALREAGTDAGDVRTGAVGAGAAGPAPGRGPVLLVPVPSARRAVRTRGHDPARRIALA FT AAGELRRTGTSARVLAVLRQRYAVADQSGLDARRRLDNLAGALAVAPGGAGPLREGGTV FT VLVDDLMTTGASLAEAARAVRAATAAAVESPAGSDAYRTARSAVYPAAAGEGREERKTG FT PRMAGPYGGGGVIREAICAAVVAASPDSFEINRN" FT CDS complement(250535..252382) FT /transl_table=11 FT /gene="SCO3011" FT /gene_synonym="SCE33.13c" FT /product="putative lipoprotein" FT /note="SCE33.13c, possible lipoprotein, len: 615 aa; FT similar to TR:O05889 (EMBL:Z95121) Mycobacterium FT tuberculosis hypothetical 61.2 kD protein MTCY20B11.19c, FT 583 aa; fasta scores: opt: 228 z-score: 243.7 E(): 4.1e-06; FT 25.5% identity in 624 aa overlap. Contains properly located FT match to Prosite entry PS00013 Prokaryotic membrane FT lipoprotein lipid attachment site and possible N-terminal FT region signal peptide sequence" FT /db_xref="GOA:Q9KYX0" FT /db_xref="InterPro:IPR019606" FT /db_xref="UniProtKB/Swiss-Prot:Q9KYX0" FT /protein_id="CAB90922.1" FT /translation="MGADRGRGGRRRPARVVAYAVGGVVLLAGCAAMPDSGDLRGVEST FT PRQDPQVRVFAMPPREDAPPADIVQGFLEALTSDDPHYETARKYLTGDAAKSWRPDESA FT TVLAGGPGTESDHSGNREDANDYSVTLTGTRVATVDAQQSYAPADGVYRESVHLTRDGK FT SKQWRIDSLPPGVVMGKSDFQRNYMSVNRYYFASNTPVRAAAETGPVREPAAVADPVYV FT RRRVDPMTQVVRSLLSGPTSLLGPVVRSSFPTGTALAKNAGSLAPDDRSKLTVPLNDKA FT ARAGADKCDEMAAQLLFTLQNLTPAVQEVELRSGGEQLCSLSEDRAETVATRGSAQRPD FT YLYFVDDQDRLVRIAAGSNGTRAEPVPGPLGEGHQALRSVAVSRDEHSAAGIGLDNKLL FT YVGSLVSGGSLGDPVLASQGKTESDRLTPPSWDAQGDLWIADRNPADPRLLLLKEGAGD FT PVEVRTPGLDGRVQAVRVAADGVRIALVVEKDGKRSLLIGRIERDGKAGDVPAVTVLEL FT RSATPELEEVTAMSWAGDARLVVVGRERGGVQQIGYVQVDGSTPEASVPAALTGVKEIA FT ATEDERLPLVAYSEDLIVRLPSGLQWQKVTEGTAPVYPG" FT misc_feature complement(252293..252325) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site," FT CDS complement(252372..254438) FT /transl_table=11 FT /gene="SCO3012" FT /gene_synonym="SCE33.14c" FT /product="putative two-component system histidine kinase" FT /note="SCE33.14c, probable two-component system histidine FT kinase, len: 688 aa; similar to TR:O05890 (EMBL:Z95121) FT Mycobacterium tuberculosis MtrB, 567 aa; fasta scores: opt: FT 1355 z-score: 1302.5 E(): 0; 48.9% identity in 515 aa FT overlap and to SW:AFQ2_STRCO (EMBL:D10654) Streptomyces FT coelicolor sensor protein AfsQ2 (EC 2.7.3.-) fasta scores: FT opt: 560 z-score: 542.0 E(): 9.8e-23; 31.1% identity in 460 FT aa overlap. Contains Pfam matches to entries PF00672 DUF5, FT Domain found in bacterial signal proteins and PF00512 FT signal, Histidine kinase. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q9KYW9" FT /db_xref="InterPro:IPR002345" FT /db_xref="UniProtKB/TrEMBL:Q9KYW9" FT /protein_id="CAB90923.1" FT /translation="MARDSAASAPGSGARAGRPVGHRSVGSRLFGRVLEGGLLHGGVQG FT SPVLRLFMRWVRRPLLPVMRLWRRNIQLKVVATTLLMSLGVVLLLGFVVIGQVRNGLLD FT AKVKASQSQATGGFTAAKQKAEEAASTNGDDGTPADGRPSQNVIQWMSELVKSLSSGGQ FT SAFDVVTLPMGGESGSGRGPRASGSVDWAVSVPEALRERIDGDTAAAQSYTRIVYNSDQ FT PSQPGLVIGKQVNDPNGEPYQLYYLFPLTQEEKSLSLVRGTLATAGLFVVVLLGAIAWL FT VVRQVVTPVRMAASIAERLSAGRLQERMKVTGEDDIARLGEAFNKMAQNLQLKISQLED FT LSRMQRRFVSDVSHELRTPLTTVRMAADVIHDARVDFDPVTARSAELLADQLDRFETLL FT ADLLEISRFDAGAAALEAEPIDLREVVRRVVSGAEPLAERKGTGIRVVGDQQPVVAEAD FT ARRVERVLRNLVVNAVEHGEGRDVVVKLAAAGGAVAVAVRDYGVGLKPGEATRVFSRFW FT RADPARARTTGGTGLGLSIALEDARLHGGWLQAWGEPGGGSQFRLTLPRTADEPLRGSP FT IPLEPTDSRRNRGLNDAGLADPAVAGGADKSVGVPAQVPAGQVSARGPITPRQATVAPT FT ADPTALPGNGARVVPRPVSGARRQDGGPAPEAAGRQDAGPEDSSRQGEASRGR" FT RBS complement(252389..252393) FT misc_feature complement(252744..253379) FT /note="Pfam match to entry PF00512 signal, Histidine FT kinase, score 186.40, E-value 4.4e-52" FT misc_feature complement(253440..253649) FT /note="Pfam match to entry PF00672 DUF5, Domain found in FT bacterial signal proteins, score 52.10, E-value 1.2e-11" FT CDS complement(254440..255129) FT /transl_table=11 FT /gene="SCO3013" FT /gene_synonym="SCE33.15c" FT /product="putative two-component system response regulator" FT /note="SCE33.15c, probable two-component system response FT regulator, len: 229 aa; similar to TR:Q50447 (EMBL:Z95121) FT Mycobacterium tuberculosis MtrA, 228 aa; fasta scores: opt: FT 1141 z-score: 1397.7 E(): 0; 74.9% identity in 227 aa FT overlap, to SW:AFQ1_STRCO (EMBL:D10654) Streptomyces FT coelicolor transcriptional regulatory protein AfsQ1, 225 FT aa; fasta scores: opt: 698 z-score: 858.5 E(): 0; 47.7% FT identity in 220 aa overlap and to many other S. coelicolor FT two-component system response regulators, e.g. TR: FT CAB77324(EMBL:AL160331) putative response regulator FT SCD8A.03, 223 aa; fasta scores: opt: 695 z-score: 745.0 FT E(): 0; 50.2% identity in 223 aa overlap. Contains Pfam FT matches to entries PF00072 response_reg, Response regulator FT receiver domain and PF00486 trans_reg_C, Transcriptional FT regulatory protein, C terminal" FT /db_xref="GOA:Q9KYW8" FT /db_xref="HSSP:1B00" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9KYW8" FT /protein_id="CAB90924.1" FT /translation="MMSFMKGRVLVVDDDTALAEMLGIVLRGEGFEPSFVADGDKALAA FT FRETKPDLVLLDLMLPGRDGIEVCRLIRAESGVPIVMLTAKSDTVDVVVGLESGADDYI FT VKPFKPKELVARIRARLRRSEEPAPEQLAIGDLVIDVAGHSVKRDGQSIALTPLEFDLL FT VALARKPWQVFTREVLLEQVWGYRHAADTRLVNVHVQRLRSKVEKDPEKPEIVVTVRGV FT GYKAGPS" FT misc_feature complement(254461..254679) FT /note="Pfam match to entry PF00486 trans_reg_C, FT Transcriptional regulatory protein, C terminal, score FT 104.90, E-value 4.4e-30" FT misc_feature complement(254779..255111) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 134.40, E-value 2e-36" FT CDS complement(255134..256276) FT /transl_table=11 FT /gene="SCO3014" FT /gene_synonym="SCE33.16c" FT /product="putative translation initiation factor" FT /note="SCE33.16c, possible translation initiation factor, FT len: 380 aa; similar to TR:Q9ZUG4 (EMBL:AC005970) FT Arabidopsis thaliana putative translation initiation factor FT EIF-2B alpha subunit T6P5.3, 365 aa; fasta scores: opt: 631 FT z-score: 658.4 E(): 3.2e-29; 37.6% identity in 338 aa FT overlap. Contains Pfam match to entry PF01008 IF-2B, FT Initiation factor 2 subunit family" FT /db_xref="GOA:Q9KYW7" FT /db_xref="InterPro:IPR000649" FT /db_xref="UniProtKB/TrEMBL:Q9KYW7" FT /protein_id="CAB90925.1" FT /translation="MADQDARNGEDKRPTGIPALRWEEPPEGPVLVLLDQTRLPAEEVE FT LVCTDPAALVEAIRSLAVRGAPLLGIAGGYGVALAAVRGFEVEEAAAALAGARPTAVNL FT AVGVRRAQAAHREALAGTGDTRQAARAALAAARALHREDTEASARMAAHGLALLDELLP FT AGGHRVLTHCNTGSLVSGGEGTAFAVALAAHRSGRLRRLWVDETRPLLQGARLTAYEAA FT RNDMAYTLLTDNAAGSLFAAGEVDAVLIGADRIAADGSVANKVGSYPLAVLARYHHVPF FT VVVAPVTTVDPDTPDGASIEVEQRPGYEVTEVTAPQVPVAGAGGGIPVAPLGTQAYNPA FT FDVTPPELVTAIVTEEGVVSPVTTEALASLCARSRQVTIS" FT misc_feature complement(255188..256135) FT /note="Pfam match to entry PF01008 IF-2B, Initiation factor FT 2 subunit family, score 234.90, E-value 1.1e-66" FT CDS 256417..257805 FT /transl_table=11 FT /gene="SCO3015" FT /gene_synonym="SCE33.17" FT /product="putative integral membrane protein" FT /note="SCE33.17, possible integral membrane protein, len: FT 462 aa; similar to TR:O69657 (EMBL:AL022121) Mycobacterium FT tuberculosis hypothetical 46.4 kD protein MTV025.037, 451 FT aa; fasta scores: opt: 730 z-score: 506.4 E(): 9.5e-21; FT 38.1% identity in 412 aa overlap. Contains possible FT hydrophobic membrane spanning regions and high content in FT proline and glycine amino acid residues" FT /db_xref="InterPro:IPR018476" FT /db_xref="UniProtKB/TrEMBL:Q9KYW6" FT /protein_id="CAB90926.1" FT /translation="MNDTPGWASPGSAPSDGHEPGASGPAGPADRPAGPDQPAPPADRP FT DAEPTSPGTKWSKEQPPPGQWSAPTGPADRGQAPPPPPPGPGWGTPPPGPPGGGYGGHG FT G |