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EBI DbfetchID AL939111; SV 1; linear; genomic DNA; STD; PRO; 321250 BP. XX AC AL939111; AL049497; AL096872; AL096884; AL109661; AL109663; AL109732; AC AL109849; AL133219-AL133220; AL136500; AL355740; AL355752; AL445343; AC AL590743; AL592262; XX DT 25-OCT-2002 (Rel. 73, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 4) XX DE Streptomyces coelicolor A3(2) complete genome; segment 8/29 XX KW . XX OS Streptomyces coelicolor OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Streptomycineae; Streptomycetaceae; Streptomyces. XX RN [1] RP 1-321250 RA Bentley S.D.; RT ; RL Submitted (09-MAY-2002) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Streptomyces sequencing team, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL sdb@sanger.ac.uk XX RN [2] RX DOI; 10.1038/417141a RX PUBMED; 12000953. RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L., RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H., RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E., RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D., RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.; RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor RT A3(2)"; RL Nature 417(6885):141-147(2002). XX DR EMBL-CON; AL645882. DR RFAM; RF00634; SAM-IV. XX FH Key Location/Qualifiers FH FT source 1..321250 FT /organism="Streptomyces coelicolor" FT /strain="A3(2)" FT /mol_type="genomic DNA" FT /db_xref="taxon:1902" FT CDS complement(200..2215) FT /transl_table=11 FT /gene="SCO1964" FT /gene_synonym="SCC54.24c" FT /product="putative export associated protein" FT /note="SCC54.24c, possible export associated protein, len: FT 671aa; prediction based on the predicted function of FT surrounding genes and the short region (67-162aa) of FT similarity to TR:Q52357 (EMBL:L38824) terD, associated with FT phage inhibition, colicin resistance and tellurite FT resistance from Serratia marcescens IncHI2 plasmid R478 FT blast scores; E=2.1e-12, Identities = 40/98 (40%), FT Positives = 55/98 (56%) which may represent an active FT site." FT /db_xref="GOA:Q9Z502" FT /db_xref="InterPro:IPR003325" FT /db_xref="UniProtKB/TrEMBL:Q9Z502" FT /protein_id="CAB38154.1" FT /translation="MTAELTRGQNHPLPRARLEIRVSAGTPVVAGATLGDENGTIHGVE FT RVVHPGAPTLPGLEVSRQAAADHRLAVDLDAVPDAVHRVSVLLALPAGGQGPARFGAVA FT APFVAVTDLDGDEVASYTITGLEAESAVVALELYRRQGAWKVRAVGQGYAGGLAELLAD FT QKLSQAHQLAATIHEAVASGLARSIPAPPAAAPAHRPDHGAMPGAGPGGPVPPASPYDP FT QGPSAPGPQTPGAPGRPGGQQPYPSGPGEPATAGQPSAPAAGGPIDYSHPRRQSAAPPP FT PPPAAPASEPGRPARPVAGDATGWSMEERLYNQVWGMFEDLARTTAAYRSAVDFADSRM FT EKELDQVLSDPRSRIGGQGDAAREAARARHGQLVSQAREVLDRDVAQLVAEAEVVEPAL FT PAAFARWDNPVWHAYRVPMEIPMALRLGDLHLPEADRIRIPMLIRLPLERGLWIDSGRS FT ASLDGSFADSHEMRRLGLETAVSHAARLLAVYPAGEFTVHVIDPAGSGAQALAPLAQSG FT VLAAPPAQGAAGAADVLARLTQRVDLVQMALRGGAPDALPPGLDTSQQLLIVNDFPHGF FT DDRAVNQLRYLADEGPAVGVHLMMVADREESAGFGPLLDPLWRSLLRLTPVADDHLADP FT WVGHAWTYEPSLVPPGSQVLQQVLAQVAAARRSWDR" FT CDS complement(2340..2918) FT /transl_table=11 FT /gene="SCO1965" FT /gene_synonym="SCC54.25c" FT /product="putative export associated protein" FT /note="SCC54.25c, possible export associated protein, len: FT 192aa; similar to many associated with plasmid borne FT resistance export systems egs. TR:Q52353 (EMBL:L38824) from FT the IncHI2 plasmid R478 of Serratia marcescens (193 aa) FT fasta scores; opt: 497, z-score: 593.2, E(): 9.8e-26, FT (42.2% identity in 192 aa overlap) and SW:TERD_ALCSP terD, FT tellurium resistance protein from the pMER610 plasmid of FT Alcaligenes sp. (192 aa) fasta scores; opt: 357, z-score: FT 429.6, E(): 1.3e-16, (37.2% identity in 188 aa overlap)." FT /db_xref="GOA:Q9Z501" FT /db_xref="InterPro:IPR003325" FT /db_xref="UniProtKB/TrEMBL:Q9Z501" FT /protein_id="CAB38155.1" FT /translation="MTVNMTKGQAISLQKSDGGSLTSVRMGLGWQAAPRRGLFGSRTRE FT IDLDASAVLFADKQPVDVVFFRHLVSDDGSVRHTGDNLVGGVGQGGDDEAILVDLQRVP FT VHIDQIVFTVNSFTGQTFQEVQNAFCRLVDETNGQELARYTLAGGGAFTAQIMAKVHRA FT GQGWSMTAIGTPANGRTFQDLMPAILPVL" FT CDS complement(3061..5199) FT /transl_table=11 FT /gene="SCO1966" FT /gene_synonym="SCC54.26c" FT /gene_synonym="uvrB" FT /gene_synonym="SC3C9.01c" FT /product="ABC excision nuclease subunit B" FT /note="SCC54.26c, partial CDS, probable uvrB, ABC excision FT nuclease subunit B, len: >113aa; similar to many eg. FT SW:UVRB_MICLU uvrB, ABC excision nuclease subunit B from FT Micrococcus luteus (709 aa) fasta scores; opt: 248, FT z-score: 280.5, E(): 2.6e-08, (45.9% identity in 111 aa FT overlap)." FT /note="SC3C9.01c, uvrB, excinuclease ABC subunit B FT (fragment), len: >635 aa; highly similar to SW:UVRB_BACSU FT (EMBL:AF017113) Bacillus subtilis excinuclease ABC subunit FT B (DinA protein) UvrB or DinA or Uvr aa; fasta scores: opt: FT 2591 Z-score: 2687.6 bits: 507.5 E(): 4.3e-142; 63.667% FT identity in 600 aa overlap. Contains Pfam matches to FT entries PF00270 DEAD, DEAD/DEAH box helicase and PF00271 FT helicase_C, Helicase conserved C-terminal domain and match FT to Prosite entry PS00017 ATP/GTP-binding site motif A FT (P-loop). Also contains a possible coiled-coil region at FT approx. residues 273..290" FT /db_xref="GOA:Q8CK11" FT /db_xref="HSSP:1C4O" FT /db_xref="InterPro:IPR004807" FT /db_xref="UniProtKB/Swiss-Prot:Q8CK11" FT /protein_id="CAD55287.1" FT /translation="MRPVSQIERTVAPFEVVSPYQPSGDQPTAIAELARRVQAGEKDVV FT LLGATGTGKSATTAWMIEKLQRPTLVMAPNKTLAAQLANEFRELLPNNAVEYFVSYYDY FT YQPEAYVPQSDTYIEKDSSINEEVERLRHSATNSLLTRRDVIVVASVSCIYGLGTPQEY FT VDRMVPLRVGEEHDRDELLRRFVDIQYTRNDMAFARGTFRVRGDTIEIFPVYEELAVRI FT EMFGDEIEALSTLHPVTGEIISEDQQLYVFPASHYVAGPERLERAVNDIEKELAERLTE FT LEKQGKLLEAQRLRMRTTYDIEMLRQIGSCSGVENYSMHFDGRSPGSPPNTLLDYFPDD FT FLLVIDESHVTVPQIGAMYEGDASRKRTLVDHGFRLPSALDNRPLKWEEFQERIGQTVY FT LSATPGAYELSRSDGAVEQIIRPTGLVDPEVVVKPTEGQIDDLVHEIRRRTEKDERVLV FT TTLTKKMAEDLTDYFVELGIQVRYLHSDVDTLRRVELLRELRAGEYDVLVGINLLREGL FT DLPEVSLVAILDADKEGFLRSGTSLIQTIGRAARNVSGQVHMYADKITPAMEKAIDETN FT RRREKQVAFNKANGVDPQPLRKKINDIVAQIAREDVDTEQLLGSGYRQTKEGKGAKAPV FT PALGGQKTGGAKAARGRAKETAVTDRPAAELAEQIEDLTTRMRAAAADLQFEIAARLRD FT EVSEMKKELRQMREAGLA" FT misc_feature complement(3541..3801) FT /note="Pfam match to entry PF00271 helicase_C, Helicase FT conserved C-terminal domain, score 75.00, E-value 1.5e-18" FT misc_feature complement(4753..5166) FT /note="Pfam match to entry PF00270 DEAD, DEAD/DEAH box FT helicase, score 27.00, E-value 1.2e-07" FT misc_feature complement(5035..5058) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(5239..6117) FT /transl_table=11 FT /gene="SCO1967" FT /gene_synonym="SC3C9.02c" FT /product="putative integral membrane protein" FT /note="SC3C9.02c, possible integral membrane protein, len: FT 292 aa; similar to TR:Q9KZI4 (EMBL:AL353863) Streptomyces FT coelicolor putative integral membrane protein SCG8A.15c, FT 244 aa; fasta scores: opt: 703 Z-score: 726.3 bits: 142.1 FT E(): 7.6e-33; 48.430% identity in 223 aa overlap. Contains FT possible hydrophobic membrane spanning regions" FT /db_xref="InterPro:IPR005330" FT /db_xref="UniProtKB/TrEMBL:Q93JJ4" FT /protein_id="CAC42741.1" FT /translation="MHSTVQGFGYGLVTPLVAYLMACLGGALGLRCTARAVLVSRSWRP FT GWLALGSAAIGSGIWTMHFVAMMGFTIEHTPIRYDWLMTFASLAVAIVMVGVGIFIVGY FT RGARGTALFTGGTITGLGIASMHYLGMAGMHLDGQLTYNTFTVAVSVVIAMVAATAALW FT AAGQVRGFLWSVGAALIMGLAVTGMHYTGMAAVEVHLSGTAEPSVGGSPAELLAPMLIG FT PLAFLLLAGVVVMFDPLMVMGRPARVPAERKPGIPAHTEVPRTIRHPAHHRPRRTRHPL FT GHRRSRTPQNR" FT RBS 6399..6403 FT CDS 6409..7278 FT /transl_table=11 FT /gene="SCO1968" FT /gene_synonym="SC3C9.03" FT /product="putative secreted hydrolase" FT /note="SC3C9.03, probable secreted hydrolase, len: 289 aa; FT similar to SW:GLPQ_BACSU (EMBL:Z26522) Bacillus subtilis FT glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46) FT GlpQ, 293 aa; fasta scores: opt: 495 Z-score: 576.9 bits: FT 114.7 E(): 1.6e-24; 34.114% identity in 299 aa overlap. FT Contains possible cleavable N-terminal region signal FT peptide sequence" FT /db_xref="GOA:Q93JJ3" FT /db_xref="InterPro:IPR004129" FT /db_xref="UniProtKB/TrEMBL:Q93JJ3" FT /protein_id="CAC42742.1" FT /translation="MHVRAVAVTTTALLGVALTAPLSHARADEAGDDGPTVVAHRGASG FT YAPENTLAAVDRAAELGIRWVENDVQRTRDGELVVLHDESLARTTDVEEVFPDRSPWKV FT KDFTAAEIARLDAGSWFGSEYAGARVPTLEQYVHRVEHNHQKLLLELKSPGLYPGIEQQ FT TLKVLANEGWLDRRHVAGRLVVQSFDADSIRTVHDLKPAVKTGFLGTPAVSELPAYAEF FT ADQINPSYGSLSMSYVSAVHAFTGPHGRPLEVLTWTVNDADTARRVAGYDVDGIITNKP FT DVVRDAVD" FT CDS 7316..7870 FT /transl_table=11 FT /gene="SCO1969" FT /gene_synonym="SC3C9.04" FT /product="putative DNA-methyltransferase" FT /note="SC3C9.04, possible DNA-methyltransferase, len: 184 FT aa; similar to SW:OGT_MYCPA (EMBL:AJ011838) Mycobacterium FT paratuberculosis methylated-DNA protein-cysteine FT methyltransferase (EC 2.1.1.63) Ogt, 165 aa; fasta scores: FT opt: 355 Z-score: 399.1 bits: 80.3 E(): 1.3e-14; 40.964% FT identity in 166 aa overlap. Contains Pfam matches to FT entries PF02870 Methyltransf_1N, 6-O-methylguanine DNA FT methyltransferase, ribonuclease-like domain and PF01035 FT Methyltransf_1, 6-O-methylguanine DNA methyltransferase, FT DNA binding domain and match to Prosite entry PS00374 FT Methylated-DNA--protein-cysteine methyltransferase active FT site" FT /db_xref="GOA:Q93JJ2" FT /db_xref="HSSP:1QNT" FT /db_xref="InterPro:IPR014048" FT /db_xref="UniProtKB/TrEMBL:Q93JJ2" FT /protein_id="CAC42743.1" FT /translation="MDSHGQYEQQVVWTVVGTDIGPLLLAATHDGLVNVVFHATDATRG FT RALERLAARLGTEPVEAPGSPLLAEAIRQVEAYFAGRRRDFELPLDWSLISGFNRQVLR FT ELASGVPYGSVVGYGDLAGRVGQPGAAQAVGMAMGANPLPVVVPCHRVVESDGGIGGFG FT GGVDTKRRLLALEGVLPEPLF" FT misc_feature 7343..7591 FT /note="Pfam match to entry PF02870 Methyltransf_1N, FT 6-O-methylguanine DNA methyltransferase, ribonuclease-like FT domain, score 27.70, E-value 0.00028" FT misc_feature 7598..7867 FT /note="Pfam match to entry PF01035 Methyltransf_1, FT 6-O-methylguanine DNA methyltransferase, DNA binding FT domain, score 121.20, E-value 1.9e-32" FT misc_feature 7754..7774 FT /note="PS00374 Methylated-DNA--protein-cysteine FT methyltransferase active site" FT CDS complement(7895..8338) FT /transl_table=11 FT /gene="SCO1970" FT /gene_synonym="SC3C9.05c" FT /product="putative dioxygenase" FT /note="SC3C9.05c, possible dioxygenase, len: 147 aa; FT similar to TR:Q9I0T8 (EMBL:AE004682) Pseudomonas aeruginosa FT probable ring-cleaving dioxygenase PA2546, 143 aa; fasta FT scores: opt: 178 Z-score: 231.1 bits: 48.7 E(): 2.9e-05; FT 33.333% identity in 135 aa overlap. Contains Pfam match to FT entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance FT protein/Dioxygenase superfamily" FT /db_xref="GOA:Q93JJ1" FT /db_xref="InterPro:IPR018146" FT /db_xref="UniProtKB/TrEMBL:Q93JJ1" FT /protein_id="CAC42744.1" FT /translation="MSLGAMTDHTTRLDHIVLWVRDPVAAAGFYEKNLGLEPLRITEYA FT AGTVSFPSVRLNDETILDLAPHAMADRMRMVPGADASAGHPVNHICVSLSPHDFDALRT FT RLEEQSIPVSDLSYDSYGARGMARRSFYFGDPDGNIIEARHYE" FT misc_feature complement(7913..8284) FT /note="Pfam match to entry PF00903 Glyoxalase, FT Glyoxalase/Bleomycin resistance protein/Dioxygenase FT superfamily, score 46.90, E-value 2.9e-12" FT RBS 8448..8454 FT CDS 8465..9370 FT /transl_table=11 FT /gene="SCO1971" FT /gene_synonym="SC3C9.06" FT /product="conserved hypothetical protein" FT /note="SC3C9.06, conserved hypothetical protein, len: 301 FT aa; similar to TR:BAB36480 (EMBL:AP002560) Escherichia coli FT O157:H7 hypothetical 32.9 kDa protein ECS3057, 312 aa; FT fasta scores: opt: 837 Z-score: 923.0 bits: 178.9 E(): FT 8.4e-44; 48.495% identity in 299 aa overlap" FT /db_xref="InterPro:IPR007342" FT /db_xref="UniProtKB/TrEMBL:Q93JJ0" FT /protein_id="CAC42745.1" FT /translation="MLVLSEEVREAMDARRPVVALESTIIAHGLPRPRNLLVARELEEA FT VRQEGAVPATIAVLDGRPHVGLDKEQLERVAGEDGIRKLGHRDLPLAVASGASGATTVS FT ATALLADLAGVRVFATGGLGGVHREWTVTQDESADLGLLARTRITVVCAGVKSILDVPA FT TLQRLETLGVAVAGYGTDRFPGFYLSDSGHPVDWTLDDPGQVAAVMRAQDALDGPRSAL FT VVANPVPEQEQLDPGLHARVLADALHACEAEGVTGQAVTPFLLERLVRLTDGASLSANL FT AAVRGNVRLAARIAAAWTGA" FT CDS 9367..10302 FT /transl_table=11 FT /gene="SCO1972" FT /gene_synonym="SC3C9.07" FT /product="putative sugar kinase" FT /note="SC3C9.07, probable sugar kinase, len: 311 aa; FT similar to SW:SCRK_KLEPN (EMBL:X61004) Klebsiella FT pneumoniae fructokinase (EC 2.7.1.4) ScrK, 307 aa; fasta FT scores: opt: 294 Z-score: 321.0 bits: 67.5 E(): 2.9e-10; FT 31.541% identity in 279 aa overlap. Contains Pfam match to FT entry PF00294 pfkB, pfkB family carbohydrate kinase and FT match to Prosite entry PS00584 pfkB family of carbohydrate FT kinases signature 2" FT /db_xref="GOA:Q93JI9" FT /db_xref="InterPro:IPR000276" FT /db_xref="UniProtKB/TrEMBL:Q93JI9" FT /protein_id="CAC42746.1" FT /translation="MSLAPGGALLVVGDVVTDIVARHRGPLAPGTDTAAAVRRLPGGAG FT ANVACWAAHEGCGDVRLLGRVGTDASAWHERELTACGVRPLLVVDSAAPTGTVICLVDT FT ADSAERTFLTDSGAALRIGPGDWSDTLLDGVGRLHLSGYLLFSEPGRALVSVALAAARA FT RGVPVSLDPASAGFLTELGVDRFLGLVEGVDVLLPSRDEACLLTGLPDVADAAAKLSRH FT VPLVIVKQGAKGALVARSGTVGARVAAVTAAPRDSTGAGDAFTGAFLAALLAGAEAEEA FT TAAGCRAGARAVERVGGRPPRAAGRGPGDG" FT misc_feature 9382..10278 FT /note="Pfam match to entry PF00294 pfkB, pfkB family FT carbohydrate kinase, score 166.90, E-value 3.4e-46" FT misc_feature 10132..10173 FT /note="PS00584 pfkB family of carbohydrate kinases FT signature 2" FT CDS complement(10316..11110) FT /transl_table=11 FT /gene="SCO1973" FT /gene_synonym="SC3C9.08c" FT /product="conserved hypothetical protein" FT /note="SC3C9.08c,conserved hypothetical protein, len: 264 FT aa; low similarity to SW:YT37_STRFR (EMBL:M29297) FT Streptomyces fradiae hypothetical 37.1 kDa protein in FT transposon TN4556, 345 aa; fasta scores: opt: 224 Z-score: FT 256.6 bits: 55.5 E(): 1.1e-06; 29.259% identity in 270 aa FT overlap" FT /db_xref="GOA:Q93JI8" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:Q93JI8" FT /protein_id="CAC42747.1" FT /translation="MTRTDGYLLDNGQSEAAERFDAFATLFDPTTFRHLEALGVGPGWR FT CWEVGAGGTSVASWLAKRVGPTGRVLATDIDTSRVAPAGRPPVEVRVHDVGAEEPPGEG FT FDLVHARLVLVHVPDRDRALRSMIKALRPGGRLLVEDADPALQPLLCPDEHGPEQALAN FT RLRHGFRQLLSGRGADLSYGRRLPRLLREAGLRRVEADAYFPVTSAACAALESATVRQV FT RDQLVAAQVATHDDIDRHLANVASGGMDLATAPMISAWGRKG" FT RBS 11346..11349 FT CDS join(11356..12387,12389..12481) FT /pseudo FT /transl_table=11 FT /gene="SCO1974" FT /gene_synonym="SC3C9.09" FT /product="pseudogene, putative metal-transport protein" FT /note="SC3C9.09, pseudogene, possible metal-transport FT protein, len: 374 aa; similar to TR:Q9FBK1 (EMBL:AL390975) FT Streptomyces coelicolor putative metal-transport protein FT SCP8.20c, 371 aa; fasta scores: opt: 1440 Z-score: 1610.3 FT bits: 306.6 E(): 4.4e-82; 60.929% identity in 366 aa FT overlap. Contains Pfam match to entry PF01544 CorA, FT CorA-like Mg2+ transporter protein and possible hydrophobic FT membrane spanning regions in C-terminal domain" FT /db_xref="PSEUDO:CAD55288.1" FT misc_feature 11572..12375 FT /note="Pfam match to entry PF01544 CorA, CorA-like Mg2+ FT transporter protein, score 197.90, E-value 1.6e-55" FT CDS complement(12500..13132) FT /transl_table=11 FT /gene="SCO1975" FT /gene_synonym="SC3C9.10c" FT /product="hypothetical protein SC3C9.10c" FT /note="SC3C9.10c, unknown, len: 210 aa" FT /db_xref="UniProtKB/TrEMBL:Q93JI7" FT /protein_id="CAC42749.1" FT /translation="MRLEAITWDRLGDRLAERLLDLEPTDGSAWTRVALDGAPAARPGD FT LAERVGEALRVRGRPSLVVGTEGFLRPASLRLEYGHHDAESYYNGWYDTAALWREVFDP FT LGPGGNGRVLPDLWDPVTDRATRSPYAQLPSGGALLLHGPFLLRHWFPLDLSVHLVLTP FT GALRRRTPGTEQWTLPAFERYDQETDPAGTADVLVRADDPRHPAWSG" FT RBS 13333..13336 FT CDS 13347..13826 FT /transl_table=11 FT /gene="SCO1976" FT /gene_synonym="SC3C9.11" FT /product="putative integral membrane protein" FT /note="SC3C9.11, possible integral membrane protein, len: FT 159 aa; similar to TR:BAB50721 (EMBL:AP003003) Rhizobium FT loti MLR3943 protein, 158 aa; fasta scores: opt: 409 FT Z-score: 476.8 bits: 94.4 E(): 6e-19; 40.667% identity in FT 150 aa overlap. Contains possible hydrophobic membrane FT spanning regions" FT /db_xref="InterPro:IPR018726" FT /db_xref="UniProtKB/TrEMBL:Q93JI6" FT /protein_id="CAC42750.1" FT /translation="MGEGPYFVLTVLGVLGTGVTAGVFCAFSTFVMRGLAALPPAQGVA FT AMNAINTAAVRPAFMSVFLGTAVLAAVTAVVTLVLWPEDAAVELLLGSGLFLAGSFGVT FT AAANVPRNAALLRLEPGAAEAAERWPAYVREWTAWNHVRAVASAAAAVAYVLALA" FT CDS 13989..15479 FT /transl_table=11 FT /gene="SCO1977" FT /gene_synonym="SC3C9.12" FT /product="putative glutamate synthase small subunit" FT /note="SC3C9.12c, possible glutamate synthase small FT subunit, len: 496 aa; similar to C-terminal part of FT SW:GLSN_MEDSA (EMBL:L01660) Medicago sativa glutamate FT synthase [NADH], chloroplast precursor (EC 1.4.1.14) FT (NADH-GOGAT) GlsN, 2194 aa; fasta scores: opt: 1473 FT Z-score: 1543.9 bits: 297.3 E(): 2.2e-78; 47.551% identity FT in 490 aa overlap and to TR:Q9S2Z0 (EMBL:AL109849) FT Streptomyces coelicolor putative glutamate synthase small FT subunit SC3A3.03c, 487 aa; fasta scores: opt: 2145 Z-score: FT 2259.1 bits: 427.5 E(): 3.2e-118; 66.398% identity in 497 FT aa overlap. Contains Pfam match to entry PF00070 pyr_redox, FT Pyridine nucleotide-disulphide oxidoreductase" FT /db_xref="GOA:Q93JI5" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q93JI5" FT /protein_id="CAC42751.1" FT /translation="MADPKGFLTTPREEWPRRPAGERVRDWDEVYVPGALLPIVGRQAD FT RCMDCGVPFCHEACPLGNLIPEWNDLVSRSDWRAASERLHATNNFPEFTGRLCPAPCEA FT GCVLAINQPAVTIKNVECAIADTAWEEGFVPPLPPERLSGRTVAVIGSGPAGLAAAQQL FT TRAGHTVAVYERDDRIGGLLRYGIPAFKMEKRHLERRVGQMRAEGTRFRTSAAVGRDVD FT AAALRTRYDAVVIATGATAWRELTVPGRELAGVHQAMEYLPLANRVCEGDLERSPLSAA FT GRHVVVVGGGDTGADCLGTAVREGAASVTQLDIYARPGAERDERAEPWPTYPRLYRLSA FT AHEEARDLRSAPAADADARLFAASTLRFTGDERGHVRALHLVGVDTGRRPLPGSERSLP FT ADLVLLALGFSGPDRHDGLVDGLGLDMEPRGTITRDRGFATNVPGVFAAGDAARGQSLV FT VWAIAEGRAVAAAVDRHLSGGSTRLPAPVGPYDRPMTA" FT misc_feature 14424..15368 FT /note="Pfam match to entry PF00070 pyr_redox, Pyridine FT nucleotide-disulphide oxidoreductase, score 101.70, E-value FT 1.4e-26" FT CDS complement(15630..15905) FT /transl_table=11 FT /gene="SCO1978" FT /gene_synonym="SC3C9.13c" FT /product="putative AbaA-like protein" FT /note="SC3C9.13c, possible AbaA-like protein, len: 91 aa; FT similar to TR:Q9F3E1 (EMBL:AL450289) Streptomyces FT coelicolor putative AbaA-like protein SC2H2.14, 89 aa; FT fasta scores: opt: 371 Z-score: 479.1 bits: 93.2 E(): FT 4.5e-19; 69.863% identity in 73 aa overlap and to TR:Q53896 FT (EMBL:X60316) Streptomyces coelicolor AbaA gene (putative FT regulator) SCF42.13, 75 aa; fasta scores: opt: 220 Z-score: FT 293.4 bits: 58.6 E(): 9.9e-09; 50.000% identity in 74 aa FT overlap" FT /db_xref="InterPro:IPR007278" FT /db_xref="UniProtKB/TrEMBL:Q93JI4" FT /protein_id="CAC42752.1" FT /translation="MNRIKPQRSPLNRAERIYNGMPARDLGSEGWHKPWSGGNGGNCLE FT AMKLADGRIAVRQSTDPDGPALIYTSAEMTAFIEGAKAGEADFLLS" FT CDS complement(15906..16766) FT /transl_table=11 FT /gene="SCO1979" FT /gene_synonym="SC3C9.14c" FT /product="putative DNA-binding protein" FT /note="SC3C9.14c, probable DNA-binding protein, len: 286 FT aa; similar to many Streptomyces DNA-binding proteins e.g. FT TR:Q9F3E2 (EMBL:AL450289) Streptomyces coelicolor putative FT DNA-binding proteins SC2H2.13, 290 aa; fasta scores: opt: FT 1019 Z-score: 1178.0 bits: 225.9 E(): 5.2e-58; 55.000% FT identity in 280 aa overlap and TR:O86719 (EMBL:AL031515) FT SC5C7.22c, 287 aa; fasta scores: opt: 1360 Z-score: 1390.2 FT bits: 265.1 E(): 1e-71; 69.338% identity in 287 aa overlap. FT Contains Pfam match to entry PF01381 HTH_3, FT Helix-turn-helix and a possible helix-turn-helix motif at FT residues 28..49 (+4.23 SD)" FT /db_xref="GOA:Q93JI3" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q93JI3" FT /protein_id="CAC42753.1" FT /translation="MSEPRSAPTVGQVVLGRRLLDLRERAGLKREEAARILRVAPATVR FT RMEMAEVALKIPYLQLLLKAYGVGDEEADAFVQLAEDANKPGWWQRFHDILPGWFSLYV FT SLEGAASLIRAYEPHFVPGVLQTEDYARGVLRSGAIGQTRPDDIERHVDLRMQRQELLT FT RKDAPRLWVVMDETALRRPVGGPEVMRAQIDRLLEATKLPNVTLQIAPFSSGPHPGTYG FT PFVLFRFAMPELPDMVYSEYLTGAVYLDARAEVATHLEVMDRMAAQAATAHRTKEILRD FT LRKEL" FT RBS complement(15912..15917) FT misc_feature complement(16548..16712) FT /note="Pfam match to entry PF01381 HTH_3, Helix-turn-helix, FT score 33.00, E-value 7e-06" FT RBS complement(16771..16779) FT CDS 17050..17763 FT /transl_table=11 FT /gene="SCO1980" FT /gene_synonym="SC3C9.15" FT /product="hypothetical protein" FT /note="SC3C9.15, hypothetical protein, len: 237 aa; similar FT to TR:O86675 (EMBL:AL031371) Streptomyces coelicolor FT hypothetical 21.4 kDa protein SC4G2.02c, 196 aa; fasta FT scores: opt: 248 Z-score: 277.4 bits: 58.4 E(): 7.7e-08; FT 34.239% identity in 184 aa overlap. Contains Pfam match to FT entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, FT phytochrome-like ATPase and a TTA leucine codon, possible FT target for bldA regulation" FT /db_xref="GOA:Q93JI2" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q93JI2" FT /protein_id="CAC42754.1" FT /translation="MASVIPSAPLGTDAAAGSLGLGAAMGAGASGAAAAERRFRFELAA FT HPGSPSQARRLTRARLSGWAVCEDTCDTAALVVSELVTNAIVHTASRHIVCELHDADDL FT VRIAVRDEGCAPGQPHPSADQQPEDEHGRGLILVDALCEAWGAHEHGPGLLVWAELPRK FT ADEPRDPAEPHNDLGWGARPKPAPTDDTGDEGEAESRRREDHRPREARGITEPRGTTES FT RKDRETLRGTGTEWL" FT misc_feature 17077..17079 FT /gene="none" FT /note="TTA leucine codon. Possible target for bldA FT regulation" FT misc_feature 17278..17391 FT /note="Pfam match to entry PF02518 HATPase_c, Histidine FT kinase-, DNA gyrase B-, phytochrome-like ATPase, score FT 20.40, E-value 0.0003" FT CDS 17760..18194 FT /transl_table=11 FT /gene="SCO1981" FT /gene_synonym="SC3C9.16" FT /product="conserved hypothetical protein" FT /note="SC3C9.16, hypothetical protein, len: 144 aa; similar FT to C-terminal part of TR:Q9F397 (EMBL:AL450165) FT Streptomyces coelicolor hypothetical 21.9 kDa protein FT SC5F1.32c, 205 aa; fasta scores: opt: 395 Z-score: 465.9 FT bits: 92.6 E(): 2.4e-18; 43.165% identity in 139 aa FT overlap" FT /db_xref="UniProtKB/TrEMBL:Q93JI1" FT /protein_id="CAC42755.1" FT /translation="MRAASGVRPLGLDTMVRLQRGRHTAGTPRRLPVPDGMTAPLGCDA FT VAVPALLGQQVLPRLPRVGCVYADETHWWWIVPSDSDYALEWPAPARYATGAIVPGSTS FT LPALLHRSDGTVPYTPPIPLYLALCRLTNTTPTWSRTVSA" FT CDS complement(18213..18395) FT /transl_table=11 FT /gene="SCO1982" FT /gene_synonym="SC3C9.17c" FT /product="hypothetical protein" FT /note="SC3C9.17c, hypothetical protein, len: 60 aa; similar FT to SCP1 borne TR:Q9AD30 (EMBL:AL590463) Streptomyces FT coelicolor hypothetical 6.3 kDa protein SCP1.120, 59 aa; FT fasta scores: opt: 224 Z-score: 325.4 bits: 63.6 E(): FT 1.6e-10; 66.667% identity in 45 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q93JI0" FT /protein_id="CAC42756.1" FT /translation="MNGRTVLERFPAGGPRGSWPAEEFAQARRLEGMPAEVVMDLATDM FT FLVVVRRDTAGDAAA" FT RBS complement(18400..18406) FT CDS complement(18551..19240) FT /transl_table=11 FT /gene="SCO1983" FT /gene_synonym="SC3C9.18c" FT /product="conserved hypothetical protein" FT /note="SC3C9.18c, conserved hypothetical protein, len: 229 FT aa; similar to TR:BAB49166 (EMBL:AP002998) Rhizobium loti FT MLR1911 protein, 249 aa; fasta scores: opt: 689 Z-score: FT 839.8 bits: 162.8 E(): 3.6e-39; 50.000% identity in 234 aa FT overlap. Contains a TTA leucine codon, possible target for FT bldA regulation" FT /db_xref="InterPro:IPR010296" FT /db_xref="UniProtKB/TrEMBL:Q93JH9" FT /protein_id="CAC42757.1" FT /translation="MSLPEIVTRADWRAAREALLAKEKAATRARDALNAERRGLPMVEV FT DKEYVFEGGDGKATLLDLFEGREQLVVYHFMFAPEWDAGCRSCSAFLDQIAHLAHLRAR FT GTSFAAVSRAPYPRILPFKARMGWTLPWYSSYVSDFNTDFEATLEHEGELVERPGLSCF FT LRDRERVFHTYSTYERGLDGLGSTTSLLDLTALGRREPWEKPEGRASALGAPAGSRGVR FT YHDEYED" FT misc_feature complement(19184..19186) FT /gene="none" FT /note="TTA leucine codon. Possible target for bldA FT regulation" FT RBS complement(19248..19254) FT CDS complement(19378..20775) FT /transl_table=11 FT /gene="SCO1984" FT /gene_synonym="SC3C9.19c" FT /product="putative hydrolase" FT /note="SC3C9.19c, probable hydrolase, len: 465 aa; similar FT to SW:ATZA_PSESD (EMBL:U55933) Pseudomonas sp. atrazine FT chlorohydrolase (EC 3.8.1.8) AtzA, 474 aa; fasta scores: FT opt: 448 Z-score: 490.2 bits: 100.0 E(): 1.1e-19; 33.258% FT identity in 445 overlap. Contains Pfam match to entry FT PF01685 ATZ_TRZ, Chlorohydrolase" FT /db_xref="GOA:Q93JH8" FT /db_xref="HSSP:1P1M" FT /db_xref="InterPro:IPR006680" FT /db_xref="UniProtKB/TrEMBL:Q93JH8" FT /protein_id="CAC42758.1" FT /translation="MTPSSPEPTGAAGHAGHAGPADLVISGCTVLVHDDRGRIGFEQDA FT AVVVRGGVVDSVTTAAAGASVPAADRIDARGQVALPGLINCHTHSPMVALRGLAEDLPT FT EEWFNDVVWPVESNLTGRDVMLGARLACAEMIRAGVTTFADSYFHMDAVAEVVDRCGMR FT AQLGQAYFSSQGPEGPAASLDFALRRRGFAGGRITTALAPHAPYTVVDADLAATAELAR FT DHGLPVHLHAAENRDQTDTSLARHGVTPIGVLERTGVLDTDVLIAHGTGITEDDLPLLA FT RAGGRTAVATAPRGYLKFGWPGTTPVRALRDIGVPVGLATDGAASNNSLDVWESMALTS FT LIQKSTEGDPRWLTSRQALHHATVQSARAVGLGDSVGRIAPGWRADLILVDLTGPHTQP FT VHDLAATLVHSARSADVRTTIVDGRVLMRDRELLTVDVSEVVRELGERLPALTDRGHGR FT RIQQYDT" FT misc_feature complement(19507..20373) FT /note="Pfam match to entry PF01685 ATZ_TRZ, FT Chlorohydrolase, score 258.60, E-value 8.6e-74" FT CDS complement(20775..22631) FT /transl_table=11 FT /gene="SCO1985" FT /gene_synonym="SC3C9.20c" FT /product="putative integral membrane protein" FT /note="SC3C9.20c, possible integral membrane protein, len: FT 618 aa; similar to TR:Q9FBT3 (EMBL:AL391072) Streptomyces FT coelicolor putative integral membrane protein SC9A4.21, 645 FT aa; fasta scores: opt: 889 Z-score: 886.0 bits: 174.1 E(): FT 9.6e-42; 35.055% identity in 639 aa overlap. Contains FT possible hydrophobic membrane spanning regions at the FT N-terminal domain" FT /db_xref="UniProtKB/TrEMBL:Q93JH7" FT /protein_id="CAC42759.1" FT /translation="MFRTAAHALPPWLGHALNAQRGPVPWNAVVRGALAGGPLLSAALV FT AGRASLGVVAAIAAMLAGINDRPGSRRTSVRRIGVPALAGALGLLVGTYAGRHLGAVAL FT TLVLTGLGLVAGCVSAVGPVASGAGTQLLVTAAVGAGMPLPDPGWRSVLAFLAGAGWLL FT LLRLVLPTPTSVTGDLRLDFRFDGERAAVADVYEAVAALLDAVGTEHAVARRAALTAAL FT DHAQDALAGPRLRRRAATAAERRLHAQYAAALPLGEAATALAWAERAVPPRAGEGPRRL FT AAAVRGNTHAGPLPAPSRTEPALRALDDALLHAAQAFDRGRGPDLHVRRRSPRSVAQAV FT LGPGGREYGLRAGLCFGAGAAVAQALHHGHWYGSHQHWYWLPATAVFLVKPDLGPLVSR FT VLCRAAGTVLGALLFAGFAAVLPRPEGLVVLVAVCGALVPVAARHFAAQTTVVTVLVLA FT LVMVGGEPQASAGRIGETLLACAIVLVAGHLPMPGQRGAGIRAGVDAADAAAHAYLTHV FT LSESDDRAARWTLRREAYRTLAEARAAIARAAAELPALARHSEGTDEVAAVLERLVDTT FT TACAVHLDDTGRLTPRHTERLAALRDELAERRGRVGGHRTLA" FT RBS complement(22643..22648) FT CDS complement(22799..23581) FT /transl_table=11 FT /gene="SCO1986" FT /gene_synonym="SC3C9.21c" FT /product="hypothetical protein" FT /note="SC3C9.21c, hypothetical protein, len: 260 aa; low FT similarity to TR:O54361 (EMBL:U73025) Staphylococcus aureus FT transposon TN5405 ORFX (hypothetical 32.9 kDa protein), 289 FT aa; fasta scores: opt: 241 Z-score: 283.5 bits: 60.2 E(): FT 3.5e-08; 28.251% identity in 223 aa overlap" FT /db_xref="GOA:Q93JH6" FT /db_xref="InterPro:IPR002934" FT /db_xref="UniProtKB/TrEMBL:Q93JH6" FT /protein_id="CAC42760.1" FT /translation="MPTPTLTDQAFLDTTADRLAALPAVRAVTLGGSRAQGVHGPDSDW FT DLAVYYRGAFDPEDLRAVGWPGEVSELGAWGGGVFNGGAWLTIDERRVDVHYRDLDVVE FT HETAEAEAGRFGVEPLMFHLAGIPTYLVVAELAINKVLRGDLPRPAAYPEALRSTAPDH FT WYGTATATLAYARAGHAPRGALTQVAGALALATAQTAHAVLAVRGEWVTNEKGLVERAG FT LDGTDVLLAGLTPEPRALDDAVTRAGTLLRDALEAARS" FT RBS complement(23591..23597) FT CDS 23668..24168 FT /transl_table=11 FT /gene="SCO1987" FT /gene_synonym="SC7H2.01" FT /gene_synonym="SC3C9.22" FT /product="conserved hypothetical protein" FT /note="SC7H2.01, partial CDS, unknown, len: >90aa; similar FT to the C-terminal region of several hypothetical proteins FT both prokaryote and eukaryote egs. SW:Y709_SYNY3 FT hypothetical protein from Synechocystis sp. strain PCC6803 FT (130 aa) fasta scores; opt: 100, z-score: 145.9, E(): 0.84, FT (34.9% identity in 83 aa overlap) and SW:UK14_CAPHI from FT Capra hircus (goat) (137 aa) fasta scores; opt: 96, FT z-score: 140.4, E(): 1.7, (34.6% identity in 81 aa FT overlap)." FT /note="SC3C9.22, conserved hypothetical protein (fragment), FT len: >115 aa; similar to N-terminal region of TR:BAB48518 FT (EMBL:AP002996) Rhizobium loti MLL1058 protein, 148 aa; FT fasta scores: opt: 175 Z-score: 218.8 bits: 46.1 E(): FT 0.00014; 40.789% identity in 76 aa overlap. Contains Pfam FT match to entry PF01042 UPF0076, YjgF family" FT /db_xref="HSSP:1JD1" FT /db_xref="InterPro:IPR016160" FT /db_xref="UniProtKB/TrEMBL:Q8CK10" FT /protein_id="CAD55289.1" FT /translation="MPAASEIRVRGAAGERTIGRLPARLPGVHVIQRVTVPVLFPPPVY FT SHASVVEAGTRLAFLAGSVPLDAAGKLVGEGDPVRQAEQVLANLTEQLRAVGSGLEHVL FT STDVYVVSAETAALSAVWDVVEASGLSTGPHSSTLLGVSCLGYPGQLVEITATAVVPES FT GRP" FT misc_feature 23776..24009 FT /note="Pfam match to entry PF01042 UPF0076, YjgF family, FT score -28.50, E-value 0.35" FT CDS 24165..24716 FT /transl_table=11 FT /gene="SCO1988" FT /gene_synonym="SC7H2.02" FT /product="hypothetical protein" FT /note="SC7H2.02, possible acetyltransferase, len: 183 aa; FT similar to SW:YIAC_ECOLI hypothetical protein from FT Escherichia coli (146 aa) fasta scores; opt: 178, z-score: FT 227.9, E(): 2.3e-05, (27.2% identity in 147 aa overlap). FT Also has region of similarity to several acetyltransferases FT eg. TR:Q08414 (EMBL:X73149) nourseothricin FT acetyltransferase from Streptomyces noursei (189 aa) fasta FT scores; opt: 115, z-score: 150.4, E(): 0.47, (40.2% FT identity in 82 aa overlap). Contains Pfam match to entry FT PF00583 Acetyltransf, Acetyltransferase (GNAT) family." FT /db_xref="GOA:Q9S2L5" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9S2L5" FT /protein_id="CAB52044.1" FT /translation="MNREAGARAGADVDAGPSDDAGAGVSTDAGAEAVVLRRARAVDAR FT AAADVWLRSFAAALPTVVRPRSDSEVRAYFRHVVVERYETWVAQEDDGAVAGVMVLEGE FT ELSQLYLAPERRGCGIGDRFVALAKERRADGLSLWTFQVNAPARRFYERHGFRAVEWTD FT GDRNEEREPDVRYEWRPRSA" FT misc_feature 24270..24635 FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 43.70, E-value FT 4.2e-09." FT stem_loop 24715..24795 FT /note="Inverted repeat (Score 57: 23/26 ( 88%) matches, 0 FT gaps) with potential 28 base loop." FT CDS complement(24802..25773) FT /transl_table=11 FT /gene="SCO1989" FT /gene_synonym="SC7H2.03c" FT /product="putative aminopeptidase" FT /note="SC7H2.03c, probable aminopeptidase, len: 323 aa; FT similar to many proline aminopeptidases e.g. SW:PIP_XANCI FT proline iminopeptidase from Xanthomonas campestris pv. FT citri (313 aa) fasta scores; opt: 848, z-score: 979.3, E(): FT 0, (44.4% identity in 320 aa overlap). Contains Pfam match FT to entry PF00561 abhydrolase, alpha/beta hydrolase fold." FT /db_xref="GOA:Q9S2L4" FT /db_xref="HSSP:1AZW" FT /db_xref="InterPro:IPR002410" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2L4" FT /protein_id="CAB52045.1" FT /translation="MSLYPEIEPYDHGMLDVGDGNHVYWETCGNPHGKPAVVLHGGPGS FT RASPGLRRYFDPAAYRIVLLDQRGAGRSLPRASAPDTDMSVNTTAHLMADLERLRVHLG FT IERWLVWGVSWGSVLGLRYAQTHPGVVTELVLTGVATGSNAEVALLTRGLGNIFPEAHE FT RFLAELPPDARDGNLPAAYNRLLESPDPAVRERAARAWTDWETATIPAPPGSVARYQDP FT DFRMGFARTVTHYWGNDHFLGDGNDEGVVIRDAHLLKGIPGTLVQGSLDFGNLLGIVWR FT LHHAWPDSDLVIVDEAGHDAGTTGDEALLAATDKYARGGTAE" FT misc_feature complement(24823..25596) FT /note="Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold, score 74.20, E-value 2.7e-18." FT CDS complement(25828..26541) FT /transl_table=11 FT /gene="SCO1990" FT /gene_synonym="SC7H2.04c" FT /product="conserved hypothetical protein" FT /note="SC7H2.04c, unknown, len: 237aa; similar to FT SW:Y08N_MYCTU hypothetical protein from Mycobacterium FT tuberculosis (350 aa) fasta scores; opt: 870, z-score: FT 990.4, E(): 0, (57.1% identity in 231 aa overlap)." FT /db_xref="InterPro:IPR005122" FT /db_xref="UniProtKB/TrEMBL:Q9S2L3" FT /protein_id="CAB52046.1" FT /translation="MDTGGLSVLDRRIEGCRACPRLVEWREEVARTKRAAFADWTYWGR FT PVPGFGPPDARLLIVGLAPAAHGGNRTGRMFTGDRSGDVLYQALYDVGLASQPTAVRVD FT DGLELYGVRVTSPVHCAPPANKPTPAERDTCRSWLVQELGLLRPTLRAVVVLGAFGWQA FT ALPAFAGAGWTVPRPRPAFAHGTQVTLDAADGPDLHLFGCFHVSQRNTFTGRLTPEMLR FT DVLRTAAETAGLPAR" FT CDS 26658..27218 FT /transl_table=11 FT /gene="SCO1991" FT /gene_synonym="SC7H2.05" FT /product="hypothetical protein" FT /note="SC7H2.05, hypothetical protein, len: 186 aa; similar FT to SW:YRFH_ECOLI hypothetical protein from Escherichia coli FT (133 aa) fasta scores; opt: 228, z-score: 249.5, E(): FT 1.4e-06, (35.2% identity in 122 aa overlap)." FT /db_xref="GOA:Q9S2L2" FT /db_xref="HSSP:1DM9" FT /db_xref="InterPro:IPR002942" FT /db_xref="UniProtKB/TrEMBL:Q9S2L2" FT /protein_id="CAB52047.1" FT /translation="MASEHDEGGSGPVAAPRDGAAAAAGTPDPKTATPDPKTAAAIAAA FT EAAGPQHGESVRVDSWIWAVRLIKTRSLGATACRGGHVRVNGERVKPAYSLRVGDEVRL FT RQEGRERVVVVKRLIRKRVGAPVAVQCYVDNSPPPPPREAVAPAGIRDRGAGRPTKRDR FT REMDRLRGLEGLSSSRRDAGTRP" FT CDS complement(27270..27776) FT /transl_table=11 FT /gene="SCO1992" FT /gene_synonym="SC7H2.06c" FT /product="putative integral membrane protein" FT /note="SC7H2.06c, possible integral membrane protein, len: FT 168aa; contains possible membrane spanning hydrophobic FT regions." FT /db_xref="UniProtKB/TrEMBL:Q9S2L1" FT /protein_id="CAB52048.1" FT /translation="MSSGAAGGLYPDSSTDRSAQEIAMSETTASPAPAVPARPRGLRAA FT LRVVQVLLALFFAVASALPKLIAHSSAADTFAEMGWGDTGMYAIGVLELTGAVALLVPV FT LQSVAATALSALMVGAFVVQLTYFDGANAATPLILMVPLLVVARARRGHNEELRRLLRA FT RVRRG" FT CDS complement(27838..28524) FT /transl_table=11 FT /gene="SCO1993" FT /gene_synonym="SC7H2.07c" FT /product="hypothetical protein" FT /note="SC7H2.07c, unknown, len: 228aa;" FT /db_xref="InterPro:IPR013217" FT /db_xref="UniProtKB/TrEMBL:Q9S2L0" FT /protein_id="CAB52049.1" FT /translation="MREGHQGTGPGAITPDGCAVELYSRLPVGVEPDIVAAAVPEGARI FT LELGSGVGRMTHPLLERGFGVTAVDESAEMLERVRGARTICSPIEDLDLGERFDAVMLA FT SFLVHAGDVEVRRGLLRTCARHVAEDGCVLIQREGADYHTNLPRERVDPSGFTIRILSA FT DPVGDGVNSVRAQYEFPDAVWTQTFRARPLTREQFEEALGEAGLAVDRYLTDDGTWVRA FT VPVRQR" FT CDS 28596..28952 FT /transl_table=11 FT /gene="SCO1994" FT /gene_synonym="SC7H2.08" FT /product="putative integral membrane protein" FT /note="SC7H2.08, possible integral membrane protein, len: FT 118aa; contains possible membrane spanning hydrophobic FT region." FT /db_xref="UniProtKB/TrEMBL:Q9S2K9" FT /protein_id="CAB52050.1" FT /translation="MNARRPVVRSVRGHASFPPRRAPQYVRYRDGDPMRTGSEPATARS FT ALRARFWLSLWGLVWAIFGTAVFALTGHFGWALACGVLWLVVTADLTVILRHLRQGPHY FT QPGRDVPPYLPPRR" FT CDS complement(28961..29341) FT /transl_table=11 FT /gene="SCO1995" FT /gene_synonym="SC7H2.09c" FT /product="hypothetical protein" FT /note="SC7H2.09c, unknown, len: 126aa;" FT /db_xref="GOA:Q9S2K8" FT /db_xref="InterPro:IPR013026" FT /db_xref="UniProtKB/TrEMBL:Q9S2K8" FT /protein_id="CAB52051.1" FT /translation="MPETSGPTGRTPETDVIDFRAAEQLLAARDPRGAVKLLDGVIGAH FT PENTAARLLRARAFFAAAQLRPAELEFTIVLEREPDNAFAHFALARTYERRGCPGQARR FT HFRLAAALDPNPEYLQQARFDS" FT CDS complement(29391..29993) FT /transl_table=11 FT /gene="SCO1996" FT /gene_synonym="SC7H2.10c" FT /gene_synonym="coaE" FT /product="dephospho-CoA kinase" FT /note="SC7H2.10c, coaE, dephospho-CoA kinase, len: 200 aa; FT similar to many e.g. SW:YTAG_BACSU hypothetical protein FT from Bacillus subtilis (197 aa) fasta scores; opt: 508, FT z-score: 575.3, E(): 1e-24, (42.2% identity in 192 aa FT overlap). Also similar to the N-terminal half of FT SW:Y14N_MYCTU hypothetical protein from Mycobacterium FT tuberculosis (407 aa) fasta scores; opt: 672, z-score: FT 751.8, E(): 0, (54.3% identity in 199 aa overlap). Similar FT to SW:COAE_ECOLI (EMBL:AE000119) Escherichia coli FT dephospho-CoA kinase (EC 2.7.1.24) CoaE or B0103, 206 aa; FT fasta scores: opt: 444 Z-score: 491.1 E(): 1e-19; 44.509% FT identity in 173 aa overlap. Contains Pfam match to entry FT PF01121 UPF0038, Uncharacterized protein family UPF0038 and FT Prosite match to PS01294 Uncharacterized protein family FT UPF0038 signature" FT /db_xref="GOA:Q9S2K7" FT /db_xref="HSSP:1N3B" FT /db_xref="InterPro:IPR001977" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2K7" FT /protein_id="CAB52052.1" FT /translation="MLRVGLTGGIGAGKSEVSRLLVEHGAVLIDADRIAREVVAPGTPG FT LAAVVAAFGEDVLAEDGSLDRPKLGSIVFADPEKLAVLNGIVHPLVRERSTALEEAAAE FT DAVVVHDVPLLTENGLAPLYDLVVVVDAAPATQLDRLMRLRGMTEQDARARMAAQATRE FT QRREIADVVVDNDVPLEELRRRVEEVWDELVRGAHTE" FT misc_feature complement(29451..29990) FT /note="Pfam match to entry PF01121 UPF0038, Uncharacterized FT protein family UPF0038, score 276.70, E-value 3e-79" FT misc_feature complement(29721..29810) FT /note="PS01294 Uncharacterized protein family UPF0038 FT signature." FT CDS complement(30026..30964) FT /transl_table=11 FT /gene="SCO1997" FT /gene_synonym="SC7H2.11c" FT /product="conserved hypothetical protein" FT /note="SC7H2.11c, unknown, len: 312 aa; similar to FT TR:O07213 (EMBL:Z96072) hypothetical protein from FT Mycobacterium tuberculosis (324 aa) fasta scores; opt: 770, FT z-score: 866.1, E(): 0, (40.9% identity in 286 aa overlap)" FT /db_xref="InterPro:IPR008492" FT /db_xref="PDB:3E35" FT /db_xref="UniProtKB/TrEMBL:Q9S2K6" FT /protein_id="CAB52053.1" FT /translation="MLDPQDLYTWEPKGLAVVDMALAQESAGLVMLYHFDGYIDAGETG FT DQIVDQVLDSLPHQVVARFDHDRLVDYRARRPLLTFKRDTWSDYEEPTIEVRLVQDATG FT APFLFLSGPEPDVEWERFAAAVGQIVERLGVRLSVSFHGIPMGVPHTRPVGITPHGSRT FT DLVPGHRSPFEEAQVPGSAEALVEYRLAQAGHDVLGVAAHVPHYVARSAYPDAALTVLE FT AITAATGLVLPGIAHSLRTDAHRTQTEIDRQIQEGDEELIALVQGLEHQYDAAAGAETR FT GNMLAEPVEIPSADEIGREFERFLAEREGDG" FT CDS complement(31121..32629) FT /transl_table=11 FT /gene="SCO1998" FT /gene_synonym="SC7H2.12c" FT /gene_synonym="rpsA" FT /product="30S ribosomal protein S1" FT /note="SC7H2.12c, rpsA, 30S ribosomal protein S1, len: FT 502aa; similar to many eg. SW:RS1_ECOLI rpsA, 30S ribosomal FT protein S1 from Escherichia coli (557 aa) fasta scores; FT opt: 1016, z-score: 1019.6, E(): 0, (39.8% identity in 452 FT aa overlap). Also similar to TR:O06147 (EMBL:Z95554) 30S FT ribosomal protein S1 from Mycobacterium tuberculosis (481 FT aa) fasta scores; opt: 2420, z-score: 2422.2, E(): 0, FT (79.1% identity in 492 aa overlap). Contains four Pfam FT matches to entry PF00575 S1, S1 RNA binding domain. Also FT contains possible coiled-coil region around 400-410aa." FT /db_xref="GOA:Q9S2K5" FT /db_xref="HSSP:1SRO" FT /db_xref="InterPro:IPR003029" FT /db_xref="UniProtKB/TrEMBL:Q9S2K5" FT /protein_id="CAB52054.1" FT /translation="MTSSTETTATTPQVAVNDIGNEEAFLAAIDETIKYFNDGDIVDGV FT IVKVDRDEVLLDIGYKTEGVIPSRELSIKHDVDPNEVVAVGDEIEALVLQKEDKEGRLI FT LSKKRAQYERAWGTIEKIKEEDGIVTGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRD FT LQPYVGKELEAKIIELDKNRNNVVLSRRAWLEQTQSEVRQTFLTTLQKGQVRSGVVSSI FT VNFGAFVDLGGVDGLVHVSELSWKHIDHPSEVVEVGQEVTVEVLDVDMDRERVSLSLKA FT TQEDPWQQFARTHQIGQVVPGKVTKLVPFGAFVRVDEGIEGLVHISELAERHVEIPEQV FT VQVNDEIFVKVIDIDLERRRISLSLKQANEAFGADPSTVEFDPTLYGMAASYDDQGNYI FT YPEGFDPETNDWLEGYETQREAWETQYAEAQTRFEQHQAQVIKSREADEKAAAEGVDTA FT GAAPAASGGGGGGSYSSEGGDNSGALASDEALAALREKLAGGQS" FT misc_feature complement(31532..31753) FT /note="Pfam match to entry PF00575 S1, S1 RNA binding FT domain, score 110.50, E-value 3.1e-29" FT misc_feature complement(31790..32008) FT /note="Pfam match to entry PF00575 S1, S1 RNA binding FT domain, score 117.50, E-value 2.4e-31" FT misc_feature complement(32057..32266) FT /note="Pfam match to entry PF00575 S1, S1 RNA binding FT domain, score 71.90, E-value 1.3e-17" FT misc_feature complement(32306..32527) FT /note="Pfam match to entry PF00575 S1, S1 RNA binding FT domain, score 76.40, E-value 6.1e-19" FT CDS 33154..33816 FT /transl_table=11 FT /gene="SCO1999" FT /gene_synonym="SC7H2.13" FT /product="hypothetical protein" FT /note="SC7H2.13, hypothetical protein, len: 220 aa; similar FT to many some of which are proposed to have FT methyltransferase activity egs. TR:CAB44537 (EMBL:AL078618) FT putative ubiquinone/menaquinone methyltransferase from FT Streptomyces coelicolor (231 aa) fasta scores; opt: 199, FT z-score: 247.0, E(): 2e-06, (40.4% identity in 104 aa FT overlap) and TR:O06424 (EMBL:Z95558) hypothetical protein FT from Mycobacterium tuberculosis (234 aa) fasta scores; opt: FT 191, z-score: 237.3, E(): 6.8e-06, (42.7% identity in 96 aa FT overlap)." FT /db_xref="GOA:Q9S2K4" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:Q9S2K4" FT /protein_id="CAB52055.1" FT /translation="MWCPEGLDEVEAELLGPPEDLKGRDVLELGAGAAQCSRWLTAQGA FT RPVALDLSHRQLQHALRIGVSFPLVCADASVLPFADGSFDLACSAYGALPFVADPRLVL FT REVRRVLRPGGRFVFSVTHPLRWAFPDEPGPEGLSVSGSYFDRTPYVEQDDEGLAVYVE FT HHRTLGDRVRDVVTSGFRLVDLVEPEWPDWNTSEWGGWSPLRGHLIPGTAIFVCERD" FT CDS 33883..36879 FT /transl_table=11 FT /gene="SCO2000" FT /gene_synonym="SC7H2.14" FT /product="putative ATP-binding RNA helicase" FT /note="SC7H2.14, possible ATP-binding RNA helicase, len: FT 998 aa; similar to many proposed helicases eg. FT SW:HRPB_ECOLI ATP-dependent helicase from Escherichia coli FT (809 aa) fasta scores; opt: 889, z-score: 783.0, E(): 0, FT (33.6% identity in 998 aa overlap). Contains a repeat FT region which does not appear in homologues: 8 x FT GDDRR(R/G)QRATVES. Also contains Prosite match to PS00017 FT ATP/GTP-binding site motif A (P-loop) and PS00037 Myb FT DNA-binding domain repeat signature 1." FT /db_xref="GOA:Q9S2K3" FT /db_xref="HSSP:1LS1" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9S2K3" FT /protein_id="CAB52056.1" FT /translation="MIRYDALDALPVRGALPALHDALEEHGTAVLVAPPGTGKTTLVPL FT ALAGLLGGEGVPARRVVVAEPRRIAARAAARRMAWLLGERPGASVGYTVRGERVVGRRA FT RVEVVTTGVLLQRLQRDQELAGVDAVVLDECHERHLDADTSAAFLWDVRQALRPELRLV FT AASATTDAEGWSRLLGGAPVVEAHGVSCPVETVWAPPARAVRPPHGMRVDPALLAHVAS FT VVRRALAERGGDVLCFLPGVGEISRVAGLLGSLEDVDVLQVHGRAPAAVQDAVLAPGAR FT RRVVLATSVAESSLTVPGVRVVVDAGLAREPRVDHARGLSALTTVRASRAAARQRAGRA FT GREAPGVVYRCWTEAEDARLPRFPAPEIKVADLTAFALQAACWGDPDASGLALLDPPPG FT GAMTAARSVLEAVGAVDPAGRATERGVRLSRLGLHPRLGRALLDAAEPGAGVSPRTAPG FT AAAPAGRSGAGTGASPTRTSAPGHAGGGTAGPAAAGAGVPGADGLRSGGAEVVAEVVGL FT LSEEAPREYGDDLVSVLRAARRGGDAYGARWRAEVRRLRAAAEGGDDRRGQRATVESGD FT DRRRQRATVESGDDRRRQRATVESGDDRRRQRATVESGDDRRRQRATVESGDDRRRQRA FT TVESGDDRRRQRATVESGDDRRRQRATVESGDGGRGERVGEDVLAGLVAALAFPERVAR FT KDGGSYLMVSGTRAELPQASALRGAPWIAVAVADRPVGRGHARVQLGAAVDEETARLAA FT GALLTERDEVHWADGDVVARRVERLGAVELAVRPLADADPVLVRGALLEGLRREGLGLL FT RRSADAGLLRKRLAFLRRRLGEPWPDVTDDALLARTDEWLEPELSRARRRADLGRIDAG FT QALTRLLPWASGEATRLDELAPERILVPSGSRIRIDYDDPEQPVLAVKLQEMFGLQRSP FT EIAGVPLLVHLLSPAGRPAAVTADLASFWKDGYTGVRAELRGRYPKHPWPEDPATAEPT FT RYTKARLGK" FT misc_feature 33979..34002 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT repeat_region 35566..35877 FT /note="translates to 8 x GDDRR(R/G)QRATVES repeat in CDS FT SC7H2.14." FT CDS complement(36930..38723) FT /transl_table=11 FT /gene="SCO2001" FT /gene_synonym="SC7H2.15c" FT /product="putative secreted protein" FT /note="SC7H2.15c, putative secreted protein, len: 597 aa; FT similar to TR:O86313 (EMBL:Z98260) hypothetical protein FT from Mycobacterium tuberculosis (411 aa) fasta scores; opt: FT 548, z-score: 447.1, E(): 1.4e-17, (33.7% identity in 380 FT aa overlap). Contains possible N-terminal region signal FT peptide sequence" FT /db_xref="UniProtKB/TrEMBL:Q9S2K2" FT /protein_id="CAB52057.1" FT /translation="MAAHFDRRLRKAAVTTTVAAVAVAALSASQAPDVTADGNGRQTTA FT DNAPTSDTPPEESATGNSRYYTDLPPLNSPSPAPTTGTPASRGASEAGIPATVLDAYKK FT AESELRRAKPGCNLPWQLLAAIGKVESGQARGGRVDANGTTIGRIIGPQLDGNGFALIK FT DTDNGVYDGNSSYDNAVGPMQFIPSTWAWAGRDGNSDGKEDPNNVYDAALAAGHYLCRN FT SWDLADQADLKRAILSYNNSQDYLHTVLSWLEYYRKGTHEIPDGTGSLPVGRSDDATPG FT TRSPGRGTGASSRPQSPGTATPSPGRSPSKPPASGRPTDPGSPSTSPSTPPTDPAPPTE FT TPTPTDTVHHLENAGATGFSAIAGDTFAERISTRAETKAGEAVGKVRVRFTVLGDTDAT FT FTGGEKVAAVTTNASGVAVAPALVAGEQTGGFTVRATVIGRTVPGLDYKATVTERVADA FT LTSTGETEPTCTPGGEFADPIEVKATLKGAVADQVAVTATLIKSKDDPAENDKGPYFKD FT ADGTAVRTLTGRKTDAKGLLELPKLYADDAEGTYILRLTTPGGAALDITLTVAEAADPT FT PDPSTGPSTAPSTEPSTEPEA" FT CDS complement(39042..39398) FT /transl_table=11 FT /gene="SCO2002" FT /gene_synonym="SC7H2.16c" FT /product="hypothetical protein" FT /note="SC7H2.16c, unknown, len: 118aa;" FT /db_xref="UniProtKB/TrEMBL:Q9S2K1" FT /protein_id="CAB52058.1" FT /translation="MLHHRTTPARARTDGPARVPLLPVPVCAPGASTGRIPATVTTVLH FT RTATDLRRRLVHRAPATAAPQGTPAWQLWADLARGYLALALALLPRPRPAHTFTVFVAP FT TDTPGTRPGGPAPY" FT CDS complement(39659..42382) FT /transl_table=11 FT /gene="SCO2003" FT /gene_synonym="SC7H2.17c" FT /gene_synonym="polA" FT /product="DNA polymerase I" FT /note="SC7H2.17c, polA, DNA polymerase I, len: 907 aa; FT similar to many eg. SW:DPO1_MYCTU polA, DNA polymerase I FT from Mycobacterium tuberculosis (904 aa) fasta scores; opt: FT 3296, z-score: 3592.4, E(): 0, (57.5% identity in 909 aa FT overlap). Contains Pfam match to entry PF00476 DNA_pol_A, FT DNA polymerase family A and to entry PF01367 FT 5_3_exonuclease, 5'-3' exonuclease." FT /db_xref="GOA:Q9S2K0" FT /db_xref="HSSP:1KFD" FT /db_xref="InterPro:IPR020047" FT /db_xref="UniProtKB/TrEMBL:Q9S2K0" FT /protein_id="CAB52059.1" FT /translation="MAKTASKKTDSTSGGRPRLMLMDGHSLAYRAFFALPAENFTTATG FT QPTNAIYGFASMLANTLRDEAPTHFAVAFDVSRKTWRSEEFTEYKANRSKTPDEFKGQV FT ELIGELLDSMHVPRFAVEGFEADDVIATLATEAEAEGFDVLIVTGDRDSFQLVSEHTTV FT LYPTKGVSELTRFTPEKVFEKYGLTPAQYPDFAALRGDPSDNLPGIPGVGEKTAAKWIN FT QFGSFAELVERVDEVKGKAGQNLRDHLESVKLNRRLTELERRVELPRTVTDLERTAYDR FT KGVAVILDTLEIRNPSLRERLYAVDPGAEEAEATPVVADGVELDGTVLGTGELAGWLAE FT HGAQPLGVATVDTWALGTGSVTEVALAASDGKAAWFDPTELDEADETAFRSWLSDPDRP FT KVFHNAKGAMRVLAEHGWSVAGVGMDTALAAYLVKPGRRSFDLDALSLEYLHRELAPAA FT AADGQLAFGADEGAEAEVLMVQARAILDLGETFESRLADVGAADLLRDMELPTSALLAR FT MERHGIAADREHLQAMEQMFAGAVQQAVKEAHAAAGREFNLGSPKQLQEVLFGELNLPK FT TKKTKTGYTTDADALAWLAAQTDNELPVIMLRHREQAKLRVTVEGLIKTIAADGRIHTT FT FNQTVAATGRLSSTDPNLQNIPVRTDEGRAIRRGFVVGEGFESLMTADYSQIELRVMAH FT LSEDAGLTEAFTSGEDLHTTAAAQVFSVEQSAVDAEMRRKIKAMSYGLAYGLSAFGLSQ FT QLNIEAAEARGLMDAYFERFGGVRDYLRRVVDEARATGYTATLFGRRRYLPDLNSDNRQ FT RREAAERMALNAPIQGTAADIVKIAMLNVDKALREADLKSRMLLQVHDEIVLEIAPGER FT AAAEELVRREMANAVQLRVPLGVSVGAGPDWESAAH" FT misc_feature complement(39773..40396) FT /note="Pfam match to entry PF00476 DNA_pol_A, DNA FT polymerase family A, score 343.40, E-value 2.4e-99" FT misc_feature complement(41477..42340) FT /note="Pfam match to entry PF01367 5_3_exonuclease, 5'-3' FT exonuclease, score 478.90, E-value 4.1e-140" FT CDS 42639..44918 FT /transl_table=11 FT /gene="SCO2004" FT /gene_synonym="SC7H2.18" FT /product="putative formate dehydrogenase" FT /note="SC7H2.18, possible formate dehydrogenase, len: 759 FT aa; similar to many formate dehydrogenase e.g. FT SW:FDHF_ECOLI formate dehydrogenase H from Escherichia coli FT (715 aa) fasta scores; opt: 386, z-score: 441.8, E(): FT 2.8e-17, (26.3% identity in 670 aa overlap). Also similar FT to SW:YX31_MYCTU hypothetical protein from Mycobacterium FT tuberculosis (779 aa) fasta scores; opt: 3038, z-score: FT 3497.1, E(): 0, (59.7% identity in 767 aa overlap)." FT /db_xref="GOA:Q9S2J9" FT /db_xref="InterPro:IPR006657" FT /db_xref="UniProtKB/TrEMBL:Q9S2J9" FT /protein_id="CAB52060.1" FT /translation="MATKPPKGDPVQDAPQVSEPQHAAAGIPAIGHTLRVAQRQMGVRR FT TALTLLRVNQKDGFDCPGCAWPEGDHRHKAEFCENGAKAVAEEATLRRVTPEFFAAHSV FT ADLATRSGYWLGQQGRLTHPVYLPEGGAHYEPVTWERAFGIVAEEIAALESADEAVFYT FT SGRTSNEAAFLYQLFARELGTNNLPDCSNMCHESSGSALSETIGVGKGSVLLEDLYKSD FT LIIVAGQNPGTNHPRMLSALEKAKANGARIISINPLPEAGLERFKNPQTPKGLTAGASL FT TDLFLQIRLGGDQALFRLLNKLILETQGAVDEAFVEEHTHGYEEFAAAARAADWDDTLA FT ATGLTRAEIEEALRMVLDSERTIVCWAMGLTQHKHSVPTIREVVNFLLLRGNIGRPGAG FT VCPVRGHSNVQGDRTMGIFERPAPAFLDALEKEFGFAPPREHGYDVVRAIRALRDGEAK FT VFFAMGGNFVSASPDTEVTEAAMRRARLTVHVSTKLNRSHAVTGARALILPTLGRTERD FT LQGGGEQFVTVEDSMGMVHASRGRLEPASGQLLSEPAIVCRLARRVLGEESRTPWEEFE FT KDYATIRDRIGRVVPGFEDFNARVAHPGGFALPHAPRDERRFPTATGKANFTAAPVEFP FT ELPEGRLLLQTLRSHDQYNTTIYGLDDRYRGIRNGRRVVLVNPEDARRLGVEDGSYVDL FT VSEWRDGVERRAPGFRVVHYPTARGCAAAYYPETNVLVPLDATADTSNTPASKSVVVRL FT EQSATD" FT CDS 44962..45501 FT /transl_table=11 FT /gene="SCO2005" FT /gene_synonym="SC7H2.19" FT /product="conserved hypothetical protein" FT /note="SC7H2.19, unknown, len: 179aa; similar to many of FT undefined function egs. SW:YBDB_ECOLI hypothetical protein FT from Escherichia coli (137 aa) fasta scores; opt: 339, FT z-score: 407.0, E(): 2.5e-15, (50.0% identity in 116 aa FT overlap) and SW:CMA2_BACSU ComA protein, involved in FT competence (126 aa) fasta scores; opt: 312, z-score: 376.3, FT E(): 1.3e-13, (44.5% identity in 110 aa overlap)." FT /db_xref="HSSP:1VH9" FT /db_xref="InterPro:IPR006683" FT /db_xref="UniProtKB/TrEMBL:Q9S2J8" FT /protein_id="CAB52061.1" FT /translation="MRPAGGHADGSTKRSRPMGERQQVQFPQEVIDEYAALGVDLPALF FT SAGHLGTRMGVQIVEASADRVVGTMPVEGNTQPYGLLHGGASAVLAETLGSVGSMLHGG FT AAKIAVGVDLNCTHHRGVRSGLVTGVATPVHRGRSTATYEVVISDEQDRRVCTARLTCL FT LRDVNPGDGVRAAAAG" FT stem_loop 45498..45624 FT /note="Inverted repeat (26/28 ( 92%) matches, 0 gaps) with FT potential 93 base loop." FT CDS 45859..46404 FT /transl_table=11 FT /gene="SCO2006" FT /gene_synonym="SC7H2.20" FT /product="hypothetical protein" FT /note="SC7H2.20, unknown, len: 181aa;" FT /db_xref="UniProtKB/TrEMBL:Q9S2J7" FT /protein_id="CAB52062.1" FT /translation="MGRGGGPRPGAAAVRHRVVRGRAVPGADVRASATPPPHPARSLAR FT TLTLALLIGVSSAGCGGGPHDPTGGSAGTAPSASPPPPSGASSGPPLPLSGAELCVSAV FT GYWAREILDGGVPYGDYQSMGLSNRQYDILREVVAAARVAKREQGARAAGELTDRQVRR FT TCAERYRDGGPSVGPWQR" FT CDS 46401..46997 FT /transl_table=11 FT /gene="SCO2007" FT /gene_synonym="SC7H2.21" FT /product="hypothetical protein" FT /note="SC7H2.21, unknown, len: 198aa;" FT /db_xref="UniProtKB/TrEMBL:Q9S2J6" FT /protein_id="CAB52063.1" FT /translation="MSGVGPVEPGEDTHVRDVPQPRPRGPLALRYDRHRRTVLASAAAL FT VVLSGGGYLYTSRPQPRPAPPPPYPSQAVDLVYVAPVTGSPSTRAAGYSFTVLLSVRSG FT PPVTVTRLTQPYDGLSVTTSPAAPFQTNSHSARKIVVTLRVTECEKAPRNPGLPFLDVT FT LRNVRAIEAHSFILGSRYAQDLSRALEVACSNDSR" FT CDS 47264..48520 FT /transl_table=11 FT /gene="SCO2008" FT /gene_synonym="SC7H2.22" FT /product="putative branched chain amino acid binding FT protein" FT /note="SC7H2.22, possible branched chain amino acid binding FT protein, len: 481aa; similar to many eg. SW:LIVK_ECOLI FT leucine-specific binding protein from Escherichia coli (369 FT aa) fasta scores; opt: 360, z-score: 374.0, E(): 1.6e-13, FT (28.4% identity in 352 aa overlap). Contains possible FT N-terminal signal sequence." FT /db_xref="InterPro:IPR001828" FT /db_xref="UniProtKB/TrEMBL:Q9S2J5" FT /protein_id="CAB52064.1" FT /translation="MPGKGLIVRQRSLIAITAALAAGALTLTACGSRDDDGGSDSGNGG FT GGTTVVIGVDAPLTGDLSALGLGIKNSADLAAKTANKNKTVEGVTFKVEALDDQGQPSV FT GQQNASSFVANKDVLGVVGPLNSSVGESMQKVFDTAKLVEVSPANTGPSLTQGPDWRNK FT KVRQYKSYFRTATTDAIQGPFAAQYVYNDAKKKKVFVIDDKKTYGAGLAGTFTDEFKKL FT GGQVVGTEHINPDTKDFSSVATKVKNSGADVVYYGGEYPQAGPLSKQIKEAGAKIPLVG FT GDGIKDDTFIKLAGAAANGDLATSVGAPVEELPSAKKFVADYKTEGYKEDYAAYGGYSY FT DSAWAIIEAVKKVVEDNGGKLPDDARAKVTEAMQNVSFDGVTGKVSFDEFGDATNKQLT FT VYSVENGAFNDVKSGTYTG" FT CDS 48635..49567 FT /transl_table=11 FT /gene="SCO2009" FT /gene_synonym="SC7H2.23" FT /product="putative branched chain amino acid transport FT permease" FT /note="SC7H2.23, probable branched chain amino acid FT transport permease, len: 310aa; similar to many eg. FT SW:LIVH_SALTY high affinity branched chain amino acid FT transport permease from Salmonella typhimurium (308 aa) FT fasta scores; opt: 711, z-score: 782.4, E(): 0, (43.5% FT identity in 306 aa overlap). Contains possible membrane FT spanning hydrophobic regions." FT /db_xref="GOA:Q9S2J4" FT /db_xref="InterPro:IPR001851" FT /db_xref="UniProtKB/TrEMBL:Q9S2J4" FT /protein_id="CAB52065.1" FT /translation="MNELPQQLVNGLLLGSMYGLVAIGYTMVYGIVQLINFAHGEIFMT FT GAFGALTVYMYILPDGTSMLIALPLMLIGAVIVSTTVAVGAERFAYRPLRGAPRLAPLI FT TAIGLSLALQQAVWAWYPDAKSARPFPQIDGGPFHIGNVTLQTGDIFLFVVAPVSMAIL FT GFFVMRTRTGRGMQATAQDPDTAKLMGVDTDRIIVIAFALGAVFAAVGGVAYGLRYGQI FT EFKMGFILGLKAFTAAVLGGIGNIYGAMIGGVVLGVAETLATAYIADVPGLDKFGSQSW FT ADVWAFILLILVLLFRPQGLLGERVADRA" FT CDS 49573..51399 FT /transl_table=11 FT /gene="SCO2010" FT /gene_synonym="SC7H2.24" FT /product="putative branched chain amino acid transport FT permease" FT /note="SC7H2.24, probable branched chain amino acid FT transport permease, len: 310aa; region from 200-608aa FT similar to many eg. SW:LIVM_SALTY high affinity branched FT chain amino acid transport permease from Salmonella FT typhimurium (425 aa) fasta scores; opt: 633, z-score: FT 702.7, E(): 8.1e-32, (36.8% identity in 400 aa overlap)." FT /db_xref="GOA:Q9S2J3" FT /db_xref="InterPro:IPR001851" FT /db_xref="UniProtKB/TrEMBL:Q9S2J3" FT /protein_id="CAB52066.1" FT /translation="MTTQTTAPKKTGAPAPGDASGLIGIPAGLGRALATGGGVLTVVST FT FLAWTWTAEFPGDLTVYGYPGGLQVLVLIAGALTALFGLASYGVKGLGWLAPAGADAAL FT KFAALAAFATTWYTIIAISTKLGGVVNLEPGGYIAAAVTLVAFLGALALPFERPEPDPF FT DPDDTGWDQFKHTSSQNWQTVRAAFASKEPPPLRALPSYVEILVIVATLAVALLVFTYG FT IGTEYDELFIGFLIVAGFGFTALHRSGLIVHVTEITARHQNITVCGGFIAAACFPFTQS FT DDQYATLGVYILIFATVALGLNIVVGLAGLLDLGYVAFLGVGAYAASMVSGSPSSPFDL FT HLPFWAAVLVGAAASLVFGVLIGAPTLRLRGDYLAIVTLGFGEIFRITANNLDGTSGPD FT VTNGSNGISSIPDLKILGFDLGVSHDMGGFTLGRFANYFLLMLIITAVVVLVFRRSGDS FT RIGRAWVAIREDETAALAMGINGFRVKLIAFAVGASLAGLAGTVQAHVTYTVTPEQYLF FT AGTTPPNSAFLLAAVVLGGMGTIAGPLIGAALLFLIPNKLQFLDDYQLLAFGLALVLLM FT RFRPEGLIANRRRKLEFHEEDEAPAVLSKTGA" FT CDS 51405..52334 FT /transl_table=11 FT /gene="SCO2011" FT /gene_synonym="SC7H2.25" FT /product="putative branched chain amino acid transport FT ATP-binding protein" FT /note="SC7H2.25, probable branched chain amino acid FT transport ATP-binding protein, len: 309aa; similar to many FT eg. SW:LIVG_ECOLI branched chain amino acid transport FT ATP-binding protein from Escherichia coli (255 aa) fasta FT scores; opt: 770, z-score: 837.9, E(): 0, (46.8% identity FT in 250 aa overlap). Contains Pfam match to entry PF00005 FT ABC_tran, ABC transporter and Prosite match to PS00017 FT ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q9S2J2" FT /db_xref="HSSP:1G6H" FT /db_xref="InterPro:IPR018170" FT /db_xref="UniProtKB/TrEMBL:Q9S2J2" FT /protein_id="CAB52067.1" FT /translation="MTTDTTTKDTAPGAPAPGTTILDARGVTMRFGGLTAVNGVDLTVN FT SGEIVGLIGPNGAGKTTFFNCLTGLYIPTEGEVRYKGQVLPAKSFKVTAAGVARTFQNI FT RLFANMTVLENVLVGRHTRTKEGFWSAVLRGPGFHRAEKASRERALELLEFVGLAPKAD FT HLARNLPYGEQRKLEIARALASEPGLLLLDEPTAGMNPQETRATEELVFAIRDQGIAVL FT VIEHDMRFIFNLCDRVAVLVQGEKLVEGDSATVQGDERVVAAYLGEPLADDPGAAEAAE FT VEAAEAAQAEAARADTTTDTAAGKENDR" FT misc_feature 51543..52136 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 200.80, E-value 2.1e-56" FT misc_feature 51564..51587 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 52331..53047 FT /transl_table=11 FT /gene="SCO2012" FT /gene_synonym="SC7H2.26" FT /product="putative branched chain amino acid transport FT ATP-binding protein" FT /note="SC7H2.26, probable branched chain amino acid FT transport ATP-binding protein, len: 238aa; similar to many FT eg. SW:LIVF_ECOLI branched chain amino acid transport FT ATP-binding protein from Escherichia coli (237 aa) fasta FT scores; opt: 774, z-score: 860.8, E(): 0, (52.4% identity FT in 233 aa overlap). Contains Pfam match to entry PF00005 FT ABC_tran, ABC transporter and Prosite matches to PS00017 FT ATP/GTP-binding site motif A (P-loop) and PS00211 ABC FT transporters family signature." FT /db_xref="GOA:Q9S2J1" FT /db_xref="HSSP:1JI0" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9S2J1" FT /protein_id="CAB52068.1" FT /translation="MTALLEVEDLRVAYGKIEAVKGISFKVDAGEVVTLIGTNGAGKTT FT TLRTLSGLLKPVGGQIRFGGKSLKKVPAHQIVSLGLAHSPEGRHIFPRMTIEDNLRLGA FT FLRSDRPGIEKDIQRAYDLFPILGERRKQAAGTLSGGEQQMLAMGRALMSQPKLLMLDE FT PSMGLSPIMMQKIMATIAELKSQGTTILLVEQNAQAALSLADHGHVMEVGNIVLSGSGQ FT DLLHDESVRKAYLGED" FT misc_feature 52418..52969 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 181.20, E-value 1.7e-50" FT misc_feature 52439..52462 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 52742..52786 FT /note="PS00211 ABC transporters family signature." FT repeat_region 53061..53114 FT /note="Inverted repeat (21/24 ( 87%) matches, 0 gaps) with FT potential 6 base loop." FT CDS complement(53123..53779) FT /transl_table=11 FT /gene="SCO2013" FT /gene_synonym="SC7H2.27c" FT /product="putative two-component system response regulator" FT /note="SC7H2.27c, probable two-component system response FT regulator, len: 218aa; similar to many eg. TR:Q53894 FT (EMBL:U51332) AbsA2 response regulator from Streptomyces FT coelicolor (222 aa) fasta scores; opt: 313, z-score: 359.0, FT E(): 1.1e-12, (36.1% identity in 155 aa overlap). Also FT similar to TR:O06143 (EMBL:Z95554) hypothetical protein FT from Mycobacterium tuberculosis (205 aa) fasta scores; opt: FT 880, z-score: 986.3, E(): 0, (69.4% identity in 196 aa FT overlap). Contains Pfam match to entry PF00072 FT response_reg, Response regulator receiver domain." FT /db_xref="GOA:Q9S2J0" FT /db_xref="HSSP:1TMY" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9S2J0" FT /protein_id="CAB52069.1" FT /translation="MTAPESPQPVDVPDDDQSHVPPLTTRVVIAEDEALIRLDLKEMLE FT EEGYSVVGEAGDGEEAVELAREHRPDLVILDVKMPKMDGISAAEKIAEESIAPVLMLTA FT FSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRFTELKALEKEVADLSLRLETR FT KLVDRAKSVLQTEYGLTEPAAFRWIQKTSMDRRMSMQQVAEAVIQDAEEKKASKG" FT misc_feature complement(53372..53707) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 138.20, E-value 1.5e-37" FT tRNA 53886..53958 FT /note="tRNA Leu anticodon CAA, Cove score 48.90" FT CDS complement(54337..55773) FT /transl_table=11 FT /gene="SCO2014" FT /gene_synonym="SC7H2.28c" FT /gene_synonym="pyk1" FT /product="pyruvate kinase" FT /note="SC7H2.28c, pyk1, pyruvate kinase, len: 478 aa; FT strongly similar to many e.g. SW:KPYK_CORGL pyruvate kinase FT from Corynebacterium glutamicum (475 aa) fasta scores; opt: FT 1800, z-score: 2008.1, E(): 0, (59.6% identity in 473 aa FT overlap). Contains Pfam match to entry PF00224 PK, Pyruvate FT kinase and Prosite match to PS00110 Pyruvate kinase active FT site signature." FT /db_xref="GOA:Q9S2I9" FT /db_xref="HSSP:1E0T" FT /db_xref="InterPro:IPR018209" FT /db_xref="UniProtKB/TrEMBL:Q9S2I9" FT /protein_id="CAB52070.1" FT /translation="MRRAKIVCTLGPATDSYDQIKDLVDAGMDIARFNFSHGTHAEHEE FT RYHRVRKASDETGRSVGALADLQGPKIRLGHFGEGPVLLERGDSFTITVEEGVEGDRYI FT CGTTYAGLAEDVTPGERVLVDDGKVCLEVTGVDGTRVRTRVIEGGMVSDHKGLNLPGVA FT VSVPALSKKDEDDLRWALRAGFDVVALSFVRSGRDILDVHRIMDEEGRRLPVIAKVEKP FT QAVENIEDIVAAFDGIMVARGDLGVEMPLEQVPTVQKRAVKLAKRNAKPVIVATQMLDS FT MIDNARPTRAEASDVANAVIDGTDAVMLSGETSVGKHPTDTVRTMARIVEAAEEDILAK FT GLPPLTERNKPRTQGGAVARAAAEMGDFLGAKFLVAFTQSGDTVRRLSRYRSPIPLLAF FT TPEPATRSQLSLTWGVETFLGPHADSTDAMVDQVDELLTRYGRCEKGDVVVITAGSPPG FT VSGTTNLVRVHHIGEDDIPK" FT misc_feature complement(54361..55770) FT /note="Pfam match to entry PF00224 PK, Pyruvate kinase, FT score 587.60, E-value 7.7e-173" FT misc_feature complement(55099..55137) FT /note="PS00110 Pyruvate kinase active site signature." FT CDS 55990..57798 FT /transl_table=11 FT /gene="SCO2015" FT /gene_synonym="SC7H2.29" FT /product="putative nucleotidase" FT /note="SC7H2.29, possible secreted nucleotidase, len: 602 FT aa; similar to many e.g. SW:CN16_ECOLI periplasmic FT 2',3'-cyclic phosphodiesterase from Escherichia coli (647 FT aa) fasta scores; opt: 577, z-score: 618.9, E(): 3.8e-27, FT (32.3% identity in 595 aa overlap). Contains Pfam match to FT entry PF01009 5_nucleotidase, 5'-nucleotidase and Prosite FT match to PS00786 5'-nucleotidase signature 2. Also has FT possible N-terminal signal sequence." FT /db_xref="GOA:Q9S2I8" FT /db_xref="HSSP:2USH" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q9S2I8" FT /protein_id="CAB52071.1" FT /translation="MPLNRRKFLSRSAVTGAGVALAGAAAAPAAEAAAPAHRGGRKPKR FT YALTVLGTTDLHGHVFNWDYFKDAEYTDAAGNAQGLGRISTLVNQVREEKGRRNTLLVD FT AGDTIQGTPLTYYYAKVDPITAEGGPVHPMAQAMNAIGYDAVALGNHEFNYGIETLRRF FT EEQCDFPLLGANAVDAKTLKPAFPPYFMKTFRVKGAPPVKVAVLGLTNPGIAIWDKAYV FT QGKLAFPGLEEQAAKWVPKLRSMGADVVVVSAHSGSSGTSSYGDQVPYVENAAANVARQ FT VPGIDAILVGHAHEEIAELKVVNEETGRTVVLSEPLCFAERLTLFDFELVFERGRWHVE FT SVKASLRNSNAVEDDPRITRLLADEHEKVVAYVNQVVGTATETLTTVEARYKDAPIIDL FT ITKVQEDVVKEALAGTEYASLPVLAQASPFSRTSEIPAGDVTIRDLSSLYVYDNTLVAK FT LLTGAQLRAYLEYSAEYYVRTAAGAPVDVDKLTNANGRPDYNYDYVSGLAYEIDVAQAA FT GSRIKNLTYGGAPLDDAQQFVLAVNNYRANGGGAFPHVASAKELWSESTEIRTRIAEWA FT TAKGVLDPKDFASADWSLTRDGVPVF" FT misc_feature 56029..57678 FT /note="Pfam match to entry PF01009 5_nucleotidase, FT 5'-nucleotidase, score 257.70, E-value 1.5e-73" FT misc_feature 56416..56451 FT /note="PS00786 5'-nucleotidase signature 2." FT CDS complement(57817..59229) FT /transl_table=11 FT /gene="SCO2016" FT /gene_synonym="SC7H2.30c" FT /product="putative monooxygenase" FT /note="SC7H2.30c, possible monooxygenase, len: 470 aa; FT similar to many e.g. SW:IUCD_ECOLI L-lysine 6-monooxygenase FT from Escherichia coli (425 aa) fasta scores; opt: 393, FT z-score: 466.0, E(): 1.2e-18, (34.4% identity in 425 aa FT overlap)." FT /db_xref="GOA:Q9S2I7" FT /db_xref="UniProtKB/TrEMBL:Q9S2I7" FT /protein_id="CAB52072.1" FT /translation="MNTPAPHTPDAPRDLVGIGIGPFNLSLAALADPLTGLDAVFYDQR FT PGFRWHPGLLIDGARVQVPFLADLVTLVDPASPWTFLNHLRARERLFPFYFAERFHIER FT AEYDAYCRWVAENLPALRFHHQVDAVRWNPERDLFEVDYTQLDAGGEAEALGRTHTRNV FT VLGIGTEPHVPDPLRPLVEDPAVPVVHAADYLRHRDTLLAAGHVTVIGTGQSGAEVFLD FT LLRHRPAGRERLHWLGRTGALAPMEYSKLGLEHFTPDYTRYFHGLAEPVRDRLVAAQWQ FT LHKGIDADTTAAIHDELYRRTLDGGWPDTTLTPGVHVRTAGRIAATQVELHLEHEQQKT FT RSRLTTDAVVLATGHRERPLGRLLAGLDPYMRRDSSERPRVDDRHRLVLDPSVTGSVYV FT QNAETHTHGVGTPDLGLAAWRSATILNDLTGREPYPLPARTAFTTFGLDGGLPQIPSAR FT HHRALTPLVDGI" FT CDS complement(59226..60584) FT /transl_table=11 FT /gene="SCO2017" FT /gene_synonym="SC7H2.31c" FT /product="putative amino acid decarboxylase" FT /note="SC7H2.31c, possible amino acid decarboxylase, len: FT 452aa; similar to many eg. TR:Q43908 (EMBL:D55724) FT L-2,4-diaminobutyrate decarboxylase of Acinetobacter FT baumannii (510 aa) fasta scores; opt: 532, z-score: 544.9, FT E(): 5e-23, (31.8% identity in 431 aa overlap). Contains FT Pfam match to entry PF00282 pyridoxal_deC, FT Pyridoxal-dependent decarboxylase conserved domain." FT /db_xref="GOA:Q9S2I6" FT /db_xref="InterPro:IPR002129" FT /db_xref="UniProtKB/TrEMBL:Q9S2I6" FT /protein_id="CAB52073.1" FT /translation="MGMPPLASGPHGADALRPLLDTVLDALRAGTAARGGPLPAGGPGA FT VAARVADAAGAILPERGDPEALRVLVTALAEGAADPAHPLCAAHLHTPPLAVAAAADLA FT ASVLNPSLDSWDQAPAASALEALVTRALARETGAADAVVTTGGTESNQLAVLLARERHG FT AGLRLVHGAGAHHSLPRAAWLLGLPEPVVVPAPAGTLDPAALDEALTQVPGPHLVAATA FT GTTDAGLIDPLPEIADRCAAHGARLHVDAAYGAGLLFSERHRARLAGLEAADTVALDLH FT KLGWQPIPAGLLTVTDADDLGALHHRADYLNADDDTDAGLPDLLGRSPRTSRRPDVLKT FT AVTLKTLGRAGLGALVDAVCSLAREFADLVETHPGFELHAPPTISTVLFRPAGAGDDAV FT AAVRRALLTTGRAVLGRARADGRLWLKATLLNPHTRPDDLAALLTLVEGHVPR" FT misc_feature complement(59409..60191) FT /note="Pfam match to entry PF00282 pyridoxal_deC, FT Pyridoxal-dependent decarboxylase conserved domain, score FT 89.20, E-value 3.7e-25" FT CDS complement(60746..63253) FT /transl_table=11 FT /gene="SCO2018" FT /gene_synonym="SC7H2.32c" FT /product="putative aminopeptidase" FT /note="SC7H2.32c, possible aminopeptidase, len: 835aa; FT similar to many eg. SW:AMPN_LACDL lysyl aminopeptidase from FT Lactobacillus delbruckii ssp. lactis (842 aa) fasta scores; FT opt: 705, z-score: 805.5, E(): 0, (27.7% identity in 622 aa FT overlap). Also similar to TR:O53194 (EMBL:AL021246) FT aminopeptidase from Mycobacterium tuberculosis (861 aa) FT fasta scores; opt: 1490, z-score: 1707.1, E(): 0, (39.6% FT identity in 867 aa overlap). Contains Pfam match to entry FT PF01433 Peptidase_M1, Peptidase family M1 and Prosite match FT to PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature." FT /db_xref="GOA:Q9S2I5" FT /db_xref="InterPro:IPR006025" FT /db_xref="UniProtKB/TrEMBL:Q9S2I5" FT /protein_id="CAB52074.1" FT /translation="MSCMSVLTRDEAQTRSRLLDVHHYAIDLDLTRGDETFDSRTVIRF FT SVRGDTAGTDTFVEVKPAELRAVTLDGQPLDPAALDENRLALKNLAPGEHELRVDAAMR FT YSRTGEGMHRFTDPSDGETYVYTQLFLDDVQRIYAAFDQPDLKAVFDVAVTAPEGWTVL FT ANGVTEHTGDGRWKAATTPPISTYLVAVAAGPWHSVRTEHRGLPFGIHCRRSLAPHLDA FT DADELLEVTRACFDRYHEKFDEPYPFDSYDQAFVPEFNAGAMENPGLVTFRDEFVFRSA FT VTDTQRQTRAMVIAHEMAHMWFGDLVTLRWWDDIWLNESFAEYMGYQTTAEATRFTDTW FT TDFGVTRKAWGYDADQRPSTHPVAPENVQDTASALLNFDGISYAKGASALRQLVAWLGE FT KDFLAGINIHFERHKFANASLADFIDSLAAATDRDVHAWADAWLRTTGVDTLVPSVTGD FT NGSRTLTVRHTGERPHRIAVGLYDQNPGHEGRLTPRERLDLDVPQAEPRPIGKLPALVV FT LNDGDLSYAKVRFDADSFRTVRESLSGLPDPLTRAVVWNALRDAVRDGELSAATYLEIA FT RAHLPHESDLALVDGVLAFAAGQIADRYATPEQRPAALNTLADLCRDLIRRTEDGDHPG FT LRLIAVRHRIATAAHPDTIAAWLADGTVPGGPELDPELRWRILTRLAVLGATDEAAIAA FT ELANDPSATGQEGAARCRAALPDAEAKARAWEAMFASDDLSNYLFTATAQGFWQPEQAE FT LVRDYVPRYYPEAVALAARRGPAMADAAGRWAFPAHAVDADTLRLGRECLADADPIPAL FT RRKLTDQLDDLARALRVREAHTD" FT misc_feature complement(62096..63202) FT /note="Pfam match to entry PF01433 Peptidase_M1, Peptidase FT family M1, score 88.50, E-value 1.4e-22" FT misc_feature complement(62348..62377) FT /note="PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature." FT CDS complement(63374..63724) FT /transl_table=11 FT /gene="SCO2019" FT /gene_synonym="SC7H2.33c" FT /product="putative chorismate mutase" FT /note="SC7H2.33c, possible chorismate mutase, len: 116aa; FT similar to the N-terminal region (which has been shown to FT contain chorismate mutase activity) of SW:TYRA_ERWHE FT T-protein chorismate mutase/chorismate dehydrogenase FT bifunctional protein from Erwinia herbicola (373 aa) fasta FT scores; opt: 179, z-score: 228.0, E(): 2.2e-05, (38.5% FT identity in 78 aa overlap)." FT /db_xref="GOA:Q9S2I4" FT /db_xref="InterPro:IPR010951" FT /db_xref="UniProtKB/TrEMBL:Q9S2I4" FT /protein_id="CAB52075.1" FT /translation="MTTSNTGTGAVEPAVREELARLRDSIDNIDAAVVHMLAERFKCTQ FT QVGHLKARHQLPPADPAREAQQIARLRTLAESAKLDPAFAEKFLNFIVAEVIHHHERIA FT ESNAAGGAPATD" FT CDS 63859..64758 FT /transl_table=11 FT /gene="SCO2020" FT /gene_synonym="SC7H2.34" FT /product="hypothetical protein" FT /note="SC7H2.34, unknown, len: 299aa;" FT /db_xref="InterPro:IPR006025" FT /db_xref="UniProtKB/TrEMBL:Q9S2I3" FT /protein_id="CAB52076.1" FT /translation="MANGGPVEHGFPHLETVRAAVTALYRRLSYDTVRTFSASVAPVDV FT AFCDTDDLYLGTQRVAHELVRHYRLPDARMIVSFREMTHAANVELTAGPEYFIELNDRF FT RTHRRDIGAALAHEVMHVYLHRLDLAFPSTRDNEILTDTATTYLGAGWLLLDAYREDAA FT TSQKLGYLTPEEFGYVLAKRALLFGEDPSVWFTSPQAYTAYGKGLARARRDGQQPPLTA FT AGWAGRRRYARDRRHAEDPHAAGAAAAGDPYSFTAQPPGQLRVSFPCPTCHQRIRVPVR FT GRVRARCGLCRTVLECDT" FT CDS 64835..65428 FT /transl_table=11 FT /gene="SCO2021" FT /gene_synonym="SC7H2.35" FT /product="hypothetical protein" FT /note="SC7H2.35, hypothetical protein, len: 197 aa; similar FT to other hypothetical protein eg. TR:O06384 (EMBL:Z95436) FT hypothetical protein from Mycobacterium tuberculosis (240 FT aa) fasta scores; opt: 215, z-score: 248.4, E(): 1.6e-06, FT (28.1% identity in 199 aa overlap)." FT /db_xref="InterPro:IPR007497" FT /db_xref="UniProtKB/TrEMBL:Q9S2I2" FT /protein_id="CAB52077.1" FT /translation="MFGSGAVRAEPSLARVRPAVDVLEPSPEQAFQRAGEAVARLREVL FT RRHGVPDASVSGSRLGLSSEYDGHARGRTLLGYRCQASYAVETGALDDLERLIADVVDA FT GAHRIDGVEFDVRDRPALLDEARRRAVAAARRKAQVYAEAADARLGPVLHIQDVEAEPV FT AAFRASAAGGPPGALAPGAVEVSARVVLGFSLRH" FT CDS complement(65476..66234) FT /transl_table=11 FT /gene="SCO2022" FT /gene_synonym="SC7H2.36c" FT /product="conserved hypothetical protein" FT /note="SC7H2.36c, unknown, len: 252 aa; similar to FT SW:YCBR_BACSU hypothetical protein from Bacillus subtilis FT (243 aa) fasta scores; opt: 421, z-score: 523.5, E(): FT 7.8e-22, (32.8% identity in 229 aa overlap)" FT /db_xref="InterPro:IPR002035" FT /db_xref="UniProtKB/TrEMBL:Q9S2I1" FT /protein_id="CAB52078.1" FT /translation="MPQGRGDGGVRMAAISLTKVRETAPALVDLYKTAGVSLTKHGMAG FT TRAAVYLVVDYSGSMKPYYKDGSVQALADRVLSLSAHLDDDGIVPVVFFSTDVDAVTEI FT ALADHQGRIERIVAGLGHMGKTSYHLAMDAVIDHYLDSGARHPALVVFQTDGGPINRLA FT AERYLCKAAPLPLFWQFVGFGDPDSRQFEYLRKLDELAVPGKRVIDNAGFFHAGRDPRK FT VTDAELYDRLVGEFPQWLAAARAQGIARPS" FT CDS <66433..67291 FT /codon_start=2 FT /transl_table=11 FT /gene="SCO2023" FT /gene_synonym="SC3A3.01" FT /product="putative membrane protein" FT /note="SC3A3.01, possible membrane protein, partial CDS, FT len: >285 aa; similar to TR:O53632 (EMBL:AL021926) FT Mycobacterium tuberculosis putative transmembrane protein FT (249 aa), fasta scores; opt: 375 z-score: 425.6 E(): FT 2.3e-16, 39.4% identity in 282 aa overlap and SCH69.25C FT (EMBL:AL079308) S.coelicolor possible membrane protein (297 FT aa) (39.4% identity in 284 aa overlap). Contains FT hydrophobic, possible membrane-spanning regions" FT /db_xref="GOA:Q8CK09" FT /db_xref="InterPro:IPR002610" FT /db_xref="UniProtKB/TrEMBL:Q8CK09" FT /protein_id="CAD55290.1" FT /translation="RYICPDCMRTAPVGHQCPECVREGARSVRRARTIAGGRISTTPVV FT TYVLFALNVLAYLAELVRPELVDRFAMVGSRLVAPDGTPLTGDGVFLSSGPLRVEGVAG FT GEWERMLTGAFLHQSPFEGTFGLLHITMNMVVLWQLGRVVELMLGRTRFAVLYLLSALG FT GSVLELVLADPWQASVGASGAVFGVGAAYYVLHRRLGAEMGRVNRFMAGLLLWLVVSAW FT FTSWQGHLGGLLVGGALALAYGYAPRDGRRAAVQAGAGAALVVLLAVTAAVKVSELTGG FT SVPL" FT CDS 67305..68222 FT /transl_table=11 FT /gene="SCO2024" FT /gene_synonym="SC3A3.02" FT /product="putative chitosanase (putative secreted protein)" FT /note="SC3A3.02, probable chitosanase (putative secreted FT protein), len: 305 aa; similar to chitosanases e.g. FT SW:CHIS_STRSQ (EMBL:L07779), csn, Streptomyces sp. (strain FT N174) chitosanase precursor (278 aa), fasta scores; opt: FT 893 z-score: 1036.3 E(): 0, 58.4% identity in 233 aa FT overlap. Has an approx. 70 aa N-terminal extension not FT present in homologues which includes a possible N-terminal FT signal sequence. Contains Pfam match to entry PF01374 FT Glyco_hydro_46, Glycosyl hydrolase family 46" FT /db_xref="GOA:Q9S2Z1" FT /db_xref="HSSP:1CHK" FT /db_xref="InterPro:IPR000400" FT /db_xref="UniProtKB/TrEMBL:Q9S2Z1" FT /protein_id="CAB52859.1" FT /translation="MKRAGVLLLGALPVIAAGVYFAVPDDSADPADTAAASSSSSATAR FT SDRDDAKDRAEREREADDALIADLPPGLAAPAKKELAQQLVSSAENSTTKWRTAYGSIE FT DVGDGDGYTAGIIGFCTGTHDLLMLVERYTEDHPDNGLAEYLPALREVDGSDSHEGLDP FT GFTAAWKAEAEVPAFRAAQEAERDRVYFEPAVRLAKLDGLGTLGQFVYYDAMVFHGPDT FT DAEGFYGLRERAMAEARTPGQGGSEKAYLETFLDVRKQAMEAKRPGIDTSRVDTAQRRF FT LTAGNLKLATPLVWEMYGDTYRVP" FT misc_feature 67551..68186 FT /note="Pfam match to entry PF01374 Glyco_hydro_46, Glycosyl FT hydrolase family 46, score 247.20, E-value 2.3e-70" FT CDS complement(68384..69847) FT /transl_table=11 FT /gene="SCO2025" FT /gene_synonym="SC3A3.03c" FT /gene_synonym="gltD" FT /product="putative glutamate synthase small subunit" FT /note="SC3A3.03c, gltD, probable glutamate synthase small FT subunit, len: 487 aa; similar to bacterial glutamate FT synthases e.g. TR:Q51584 (EMBL:D85230), gltD, Plectonema FT boryanum small subunit of NADH-dependent glutamate synthase FT (492 aa), fasta scores; opt: 1295 z-score: 1405.0 E(): 0, FT 51.2% identity in 500 aa overlap. Also similar to part of FT eukaryotic glutamate synthases e.g. SW:GLSN_MEDSA FT (EMBL:L01660) Medicago sativa (Alfalfa) Glutamate synthase FT [NADH] precursor (2194 aa) (49.1% identity in 489 aa FT overlap). Contains Pfam match to entry PF00037 fer4, 4Fe-4S FT ferredoxins and related iron-sulfur cluster binding FT domains" FT /db_xref="GOA:Q9S2Z0" FT /db_xref="InterPro:IPR006005" FT /db_xref="UniProtKB/TrEMBL:Q9S2Z0" FT /protein_id="CAB52860.1" FT /translation="MADPKGFLNHGREVARTRPVDERVKDWNEVYVPGSLLPIISKQAS FT RCMDCGIPFCHNGCPLGNLIPEWNDYAYREDWSAASERLHATNNFPEFTGRLCPAPCES FT ACVLGINQPPVTIKNVEVSIIDKAWETGDVAPRIPERLSGKTVAVIGSGPAGLAAAQQL FT TRAGHTVAVYERADRVGGLLRYGIPEFKMEKRHINRRIEQMRAEGTRFRTGVEIGRDLK FT ATDLKKRYDAVVIAAGSTTARDLPVPGRELNGIHQAMEYLPLANKVQEGDYVAPPITAE FT GKHVVVIGGGDTGADCVGTAHRQGAASVTQLEIMPRPGEERDAVRQPWPTFPMLYKVTS FT AHEEGGERVYAVSTTHFEGDEDGNVQWLHMSEVEFVDGKLTSKPGTERKIPAQLVTLAM FT GFTGTDKDNGLVDQFGLELDERGNIARDADFQTNVPGVFVAGDAGRGQSLIVWAIAEGR FT SAARGADRFLTGASDLPAPIRPTDRALAV" FT misc_feature complement(69647..69718) FT /note="Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins FT and related iron-sulfur cluster binding domains., score FT 10.70, E-value 0.073" FT CDS complement(69840..74384) FT /transl_table=11 FT /gene="SCO2026" FT /gene_synonym="SC3A3.04c" FT /gene_synonym="gltB" FT /product="putative glutamate synthase large subunit" FT /note="SC3A3.04c, gltB, probable glutamate synthase large FT subunit, len: 1514 aa; similar to bacterial glutamate FT synthases e.g. TR:Q51583 (EMBL:D85230), gltB, Plectonema FT boryanum large subunit of NADH-dependent glutamate synthase FT (1530 aa), fasta scores; opt: 5662 z-score: 6172.3 E(): 0, FT 56.4% identity in 1518 aa overlap. Also similar to part of FT eukaryotic glutamate synthases e.g. SW:GLSN_MEDSA FT (EMBL:L01660) Medicago sativa (Alfalfa) Glutamate synthase FT [NADH] precursor (2194 aa) (49.9% identity in 1577 aa FT overlap)" FT /db_xref="GOA:Q9S2Y9" FT /db_xref="HSSP:1LM1" FT /db_xref="InterPro:IPR001202" FT /db_xref="UniProtKB/TrEMBL:Q9S2Y9" FT /protein_id="CAB52861.1" FT /translation="MDARPAAQGMYDPRNEHDACGVGFVATLTGEASHTLVDQALTVLR FT NLEHRGATGSEPDSGDGAGILSQVPDAFFREVAGFELPEAGAYAVGIAFLPVDGTEDAV FT SRIETIAHEEGLTVLGWREVPVAPQMLGATARSTMPVFRQVFVGDGASRGIALDRHAFA FT LRKRAEREAGVYFPSLSARTIVYKGMLTTGQLEPFFPDLSDRRFASAIALVHSRFSTNT FT FPSWPLAHPYRFVAHNGEINTVKGNRNWMRARESQLASNLFGSSADLERIFPICTPDAS FT DSASFDEVLELLHLGGRSLPHSVLMMIPEAWENHASMDADRRAFYQFHSTMMEPWDGPA FT CVTFTDGTQVGAVLDRNGLRPGRYWVTDDGLVVLGSEVGVLDIDPAKVVRKGRLQPGRM FT FLVDTAEHRIIEDDEIKAQLAGEQPYGEWMEAGEIELSDLPEREHIVHTHASVTRRQQT FT FGYTEEELRVILAPMAKAGAEPIGSMGTDSPIAALSERPRLLFDYFTQLFAQVTNPPLD FT AIREELVTSLRSSLGPQGNLLDPTAASCRSVLLPFPVIDNDELAKLIHINADGDMPGFK FT AATLSGLYRVHGGGDALAARIEEICAEADAAIENGARLIVLSDRHSDAEHAPIPSLLLT FT AAVHHHLIGTKQRTQVGLLVEAGDVREVHHVALLIGFGAAAVNPYLAMESVEDLVRAGT FT FLQTDDGEPEQAIRNLIYALGKGVLKVMSKMGISTVASYRGAQVFEAVGLDEEFVAKYF FT HGTATKIGGVGIDVVAKEVAARHAKAYPASGIAPAHRALDIGGEYQWRREGEPHLFDPE FT TVFRLQHSTRSGTYDIFKKYTERVNEQSERLMTLRGLFGFKSGRQPISIDEVEPVSEIV FT KRFSTGAMSYGSISQEAHETLAIAMNQLGGKSNTGEGGEDPERLYDPARRSSIKQVASG FT RFGVTSEYLVNADDIQIKMAQGAKPGEGGQLPGHKVYPWVAKTRHSTPGVGLISPPPHH FT DIYSIEDLAQLIHDLKNANPQARIHVKLVSEVGVGTVAAGVSKAHADVVLISGHDGGTG FT ASPLTSLKHAGGPWELGLAETQQTLLLNGLRDRIVVQTDGQLKTGRDVVIAALLGAEEF FT GFATAPLVVSGCVMMRVCHLDTCPVGIATQNPVLRERFSGKAEYIVNFFRFIAEEVREI FT LAELGYRSIEEAVGHAETLDVTRAVDHWKAQGLDLEPLFHVPALTEGAVRHQAVGQDHG FT LEKALDNQLIKLASDALAAPDATRAAPVRAQVAIRNINRTVGTMLGHEVTKKFGGGGLP FT DDTVDITFTGSAGQSFGAFVPRGITLRLEGDANDYVGKGLSGGRIVVRPDRGADHLAEY FT STIAGNTIGYGATGGEMFLRGKVGERFCVRNSGALVVSEGVGDHGCEYMTGGHAVVLGE FT TGRNFAAGMSGGIAYVVDLDRDNVNVGNVDAVQALDDADKDWLHDVVRRHAEETGSTVA FT GKLLADWPVAVERFSKIIPSTYQAVLAAKDAAERAGLSETETTEKMMEAATNG" FT CDS complement(74826..75557) FT /transl_table=11 FT /gene="SCO2027" FT /gene_synonym="SC3A3.05c" FT /product="putative membrane protein" FT /note="SC3A3.05c, possible membrane protein, len: 243 aa; FT unknown function, shows weak similarity to TR:Q9ZUA5 FT (EMBL:AC006069) Arabidopsis thaliana hypothetical protein FT (250 aa), fasta scores; opt: 347 z-score: 387.7 E(): 3e-14, FT 29.7% identity in 229 aa overlap. Contains hydrophobic, FT possible membrane-spanning regions" FT /db_xref="InterPro:IPR008217" FT /db_xref="UniProtKB/TrEMBL:Q9S2Y8" FT /protein_id="CAB52862.1" FT /translation="MAIIETEAALHEAHRDNHTHRDVNGGWLRPAVFGAMDGLVSNLAL FT MTGVAGGTASQQTVVISGLAGLAAGAFSMAAGEYTSVASQRELVEAELDVERRELRKHP FT ADEEAELAALYEARGVEPELAREVARQLSADPEQALEIHAREELGIDPSDLPSPTVAAV FT SSFGSFALGALLPVLPFLLGAGALWPAVLLALAGLFLCGAVVAKVTARSWWYSGLRQLA FT LGGAAAGVTYLLGSLFGTAVG" FT CDS 75792..77321 FT /transl_table=11 FT /gene="SCO2028" FT /gene_synonym="SC3A3.06" FT /product="putative membrane protein" FT /note="SC3A3.06, possible membrane protein, len: 509 aa; FT unknown function, probable Ser- and Pro-rich CDS suggested FT by GC frameplot, positional base preference and amino acid FT composition. Contains a compound repeat region at the FT C-terminus consisting of 22 degenerate repeats (19x FT RSPP(A/D)PD and 3x AHAPAPD). Shows weak similarity to the FT neighbouring CDS SC3A3.07, SC3A3.08 and SC3A3.09 e.g. FT SC3A3.07 hypothetical protein (425 aa) (32.1% identity in FT 383 aa overlap). Contains a hydrophobic, possible FT membrane-spanning region" FT /db_xref="InterPro:IPR005502" FT /db_xref="UniProtKB/TrEMBL:Q9S2Y7" FT /protein_id="CAB52863.1" FT /translation="MASTACIPPAAAPQDAVGLRDRARGALLGLAVGDALGAPAENMKP FT SEIRARWGRITGYVADRPAGTDDTEYAIFSGLLLARHGGALTQAHVEAAWHEWIADREE FT GPFRGAGFSERGTLENLRRGLAAPISAQHRHAWSDGLAMRAAPHGVFAAGRPAEAARLA FT AIDGSVSHEGEGIYGGQAVAAGVAAAMAGASTVAVVASALAVVPDDSWTARCLRRALTA FT AHRGERAVRSAVVIGGYPWTDLAPEAVALAFGAYAAADGDFTDSVLTAVNMGRDADTTA FT AVAGALAGATRGVHAIPADWADAIGPARGSCLPTMAGHHVLEVADLLTRASRPAPPASE FT RVRRATKRFPRNPDRSPPNPDRSPPDPDRSSPNPDRSPSDPDGTPSDPDRSSPASDRSP FT SAPAAHAPAPDRSPPDPDGRPSDPDRSSPASDRLPPASDRSPSAPAAHAPAPDWSPPDP FT DGRPSDPDRSSPASDRLPPAPDRLPPAPDRSPSAPDAHVPVPDAHPAEVAP" FT repeat_region 76833..77294 FT /note="22x 21 bp direct repeats" FT CDS 77318..78595 FT /transl_table=11 FT /gene="SCO2029" FT /gene_synonym="SC3A3.07" FT /product="putative secreted protein" FT /note="SC3A3.07, putative secreted protein, len: 425 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Shows weak similarity to the neighbouring CDS SC3A3.06, FT SC3A3.08 and SC3A3.09 e.g. SC3A3.06 possible membrane FT protein (509 aa) (32.1% identity in 383 aa overlap). FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="InterPro:IPR005502" FT /db_xref="UniProtKB/TrEMBL:Q9S2Y6" FT /protein_id="CAB52864.1" FT /translation="MSRPRGAVGATGTTAYVAGPGVPEVSGPGGSGHRPGSEPDTAAAS FT RGVPLSDRVEGLLLGLAAGDAAGWPAARHRAARMPQWTRRLTRELDTFAEQNATTTLPV FT PIALNQPPEPLRLGPSDDAEWAAFAAEALLRAGDDSVLGDLSRDRRMRAAIDLTWNAVA FT SEVAAATERAPEAESAVLPLRARISVRAGLGNLAAGLRPPATGHDNPHYFDDAACVRAC FT VLAVAHPGAPRLAADLAEFDARYTQDGDGVHGARAMAAALARALDGTDVDACVAAALAE FT LPEATEIGRNARQALALAAAAESTFALVPLLEHRIVDHVYSYGIAAAETVPVALALTVA FT ARGRLAETVPAAACLSRVADSAPALAGALTGALGGGASVPASWRDACRTLPGCVLPRLT FT GTDLVELAGLLHATRPSPPEGRDTTP" FT CDS 78592..79770 FT /transl_table=11 FT /gene="SCO2030" FT /gene_synonym="SC3A3.08" FT /product="hypothetical protein" FT /note="SC3A3.08, hypothetical protein, len: 392 aa; unknown FT function, shows very weak similarity to SW:YH24_ARCFU FT (EMBL:AE000984) Archaeoglobus fulgidus hypothetical protein FT (305 aa), fasta scores; opt: 147 z-score: 168.3 E(): 0.051, FT 30.3% identity in 333 aa overlap. Shows weak similarity to FT the neighbouring CDS SC3A3.06, SC3A3.07 and SC3A3.09 e.g. FT SC3A3.06 possible membrane protein (509 aa) (33.1% identity FT in 393 aa overlap)" FT /db_xref="InterPro:IPR005502" FT /db_xref="UniProtKB/TrEMBL:Q9S2Y5" FT /protein_id="CAB52865.1" FT /translation="MTPPTQDHSTAASLDERVTGALVGAAVGDALGGPVEGYSPEQIVE FT RHGGRVHGVVGPWNGDAWRTARPVAPYHKGDGHVTDDTLMTHALVRVYGTVRDHLDAYA FT VAEHLVPDLITNPRWIPELEAEALPLQRIFLAEKWLVARIHYGHVDPREAGTGNIVNCG FT AAMYMAPVGLVNAAHPAAAYAEALDVAGAHQSSYGREAAGVFAAAVAAACAPGATPDSV FT VAACLALAKDGTRAAIEAVCEVAACHSDFESALAPLRAAVAPYDTVGPDYRAPSLGARR FT PSRLHAIEELPVALGMLLVAGGDFRHAVLGAVNYGRDCDSIATMAGALAGALGSPVPED FT WAKTVAEASRLDLWEPAAVLTAVAREVFARDVRRRRAHEEAFAAIGGVGCSG" FT CDS 79758..81161 FT /transl_table=11 FT /gene="SCO2031" FT /gene_synonym="SC3A3.09" FT /product="hypothetical protein" FT /note="SC3A3.09, hypothetical protein, len: 467 aa; unknown FT function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Shows weak similarity to the neighbouring CDS SC3A3.06, FT SC3A3.07 and SC3A3.08 e.g. SC3A3.06 possible membrane FT protein (509 aa) (33.1% identity in 353 aa overlap). Has a FT Pro-rich C-terminus" FT /db_xref="InterPro:IPR005502" FT /db_xref="UniProtKB/TrEMBL:Q9S2Y4" FT /protein_id="CAB52866.1" FT /translation="MLRLTWVQPEDLVGHELRQARLDGRDASAVAARWRAAGGGEPPAR FT AGASPGPASPRLSRLAQDLLDELAGLPSPLAAAEPTELDRIRALCPDWPAPRPGARVSP FT ARLEAAWLGRAVGCLLGKPVEKLPLPGIRLLGRAAGNWPPTAYFTARGVPRDLLTAHPW FT NRRSAPTSLAENIDGMPEDDDLNYPLLGLLLLRRHGKAFTTGDVARVWLDELPPGRTFT FT AERVALRNLLTGLEPPHTARHRNPFREWIGALIRADVHGWTNPGDPGAAAEQAHRDATL FT SHTANGVHAAMFAAAVVAAAAPDDAPDVHACLRAGLAVVPPGSRLAGAVRHAVRLAGAH FT DDFDTVVDRLHAVHSPAHHWVHAVPNTALIAAALTHADGDFTGSVSRAVSGGWDTDSNG FT ATVGGVAGLLAGSPAALPAHWTAPLKNRLATSVGDFDGTGFDTLAHLTHRETTRPCPSP FT PPPPPSPLP" FT CDS 81119..82333 FT /transl_table=11 FT /gene="SCO2032" FT /gene_synonym="SC4G6.01" FT /gene_synonym="SC3A3.10" FT /product="hypothetical protein" FT /note="SC4G6.01, partial CDS, unknown, len: >35 aa" FT /note="SC3A3.10, hypothetical protein, len: 404 aa; unknown FT function, similar to both bacterial dehydratases e.g. FT SW:CAIB_ECOLI (EMBL:X67748) Escherichia coli L-carnitine FT dehydratase (405 aa), fasta scores; opt: 579 z-score: 647.7 FT E(): 1e-28, 28.9% identity in 409 aa overlap and to FT eukaryotic isomerases e.g. TR:O43673 (EMBL:AF047020) Homo FT sapiens alpha-methylacyl-CoA racemase (382 aa) (31.2% FT identity in 398 aa overlap). Similar to others from FT S.coelicolor e.g. SC5F2A.13 (EMBL:AL049587) S.coelicolor FT possible racemase (398 aa) (35.9% identity in 404 aa FT overlap). Present, in part, in cosmid 4G6 (EMBL:AL096884) FT as SC4G6.01" FT /db_xref="GOA:Q9S2Y3" FT /db_xref="HSSP:1PQY" FT /db_xref="InterPro:IPR003673" FT /db_xref="UniProtKB/TrEMBL:Q9S2Y3" FT /protein_id="CAB52867.1" FT /translation="MPEPAAPAPVSPPLTGLRVLDLATLFAGPLAATMLGDFGAEVIKV FT EHPTRPDPSRGHGPSKDGVGLWWKLLGRNKHTITLDLSKPAGRTTLLRLAATADVVVEN FT FRPGTLEKWDLGWDELSAVNPRLVLTRVTGFGQFGPYARRPGFGTLAEAMSGFAAMTGE FT PDAPPTLPPFGLADSIAALATAYAVMTALAARERTGEGQVVDMAIIEPILTVLGPQPLW FT YDQLGHVQPRTGNRSQNNAPRNTYRTADGTWVAVSTSAQSVAERVMRLVGRPELIDEPW FT FATGADRARHADVLDAAVGDWIARHGRADVLAAFEKAEAAVAPVQDVRDVMSDPQYQAL FT DTVTTVDDPELGPLRMQNVLFRLSATPGAIRWAGRPHGADTEEVLTGLGLTPADVKELR FT EEGVV" FT CDS 82330..83154 FT /transl_table=11 FT /gene="SCO2033" FT /gene_synonym="SC4G6.02" FT /product="putative citrate lyase beta chain" FT /note="SC4G6.02, possible citrate lyase beta chain, len: FT 274 aa; similar to SW:CILB_KLEPN citrate lyase beta chain FT from Klebsiella pneumoniae (289 aa) fasta scores; opt: 293, FT z-score: 325.3, E(): 8.5e-11, (33.5% identity in 284 aa FT overlap)." FT /db_xref="GOA:Q9S2U9" FT /db_xref="InterPro:IPR005000" FT /db_xref="UniProtKB/TrEMBL:Q9S2U9" FT /protein_id="CAB51425.1" FT /translation="MTAPPLTWLYVPGDRPRVVAKALAAGADVVVVDLEDAVAADRKEY FT ARDATAELLTEPQPVPVHVRVNALDGPLAAGDLAALAALPGLSGLRLPKVTAPEQVTGV FT AALTGGPPLYALLETALGVERAYRIAAAHPALRGIALGEADLRADLGVRGDAGLDWSRS FT RVVVAARAAGLAPPSQTVHPDTRDLEGLAASCAHGRALGFLGRAAIHPRQLPIIERAYL FT PTERELEEAETIVKAATVQPGAQALPDGRFIDAAVVATARRTLSLARRPTLS" FT CDS complement(83228..84259) FT /transl_table=11 FT /gene="SCO2034" FT /gene_synonym="SC4G6.03c" FT /product="putative prolipoprotein diacyleglyceryl FT transferase" FT /note="SC4G6.03c, possible prolipoprotein diacyleglyceryl FT transferase, len: 343aa; similar to many eg. SW:LGT_STAAU FT prolipoprotein diacyleglyceryl transferase from FT Staphylococcus aureus (279 aa) fasta scores; opt: 434, FT z-score: 465.7, E(): 1.3e-18, (32.4% identity in 250 aa FT overlap). Also similar to TR:O06131 (EMBL:Z95554) FT hypothetical protein from Mycobacterium tuberculosis (468 FT aa) fasta scores; opt: 735, z-score: 778.7, E(): 0, (46.9% FT identity in 384 aa overlap). Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q9S2U8" FT /db_xref="InterPro:IPR001640" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2U8" FT /protein_id="CAB51426.1" FT /translation="MELAFIPSPSRGVLHLGPVPLRGYAFCIIIGVFVAVWLGNKRWVA FT RGGRPGTVADIAVWAVPFGLIGGRLYHVITDYQLYFSEGRDWVDAFKIWEGGLGIWGAI FT AFGAVGAWIGARRRGVPMPAYADAVAPGIALAQAIGRWGNWFNQELYGKATDLPWAVEI FT TSTADGRVPGTYHPTFLYESLWCIGVALLVIWADRRFKLGHGRAFALYVAAYCAGRFWI FT EYMRVDDAHHILGLRLNNWTALFVFLLAVLYIVLSARKRPGREAVVEPGAETAAGDSGS FT AADKDVKGTKDAEDAEGAEDGAEKTDASGATEAPEDTSGADEADAAKDAEGVTNGADSA FT KKG" FT CDS complement(84336..85163) FT /transl_table=11 FT /gene="SCO2035" FT /gene_synonym="SC4G6.04c" FT /product="putative membrane protein" FT /note="SC4G6.04c, possible membrane protein, len: 275 aa; FT similar to TR:Q9S2S3 (EMBL:AL096884) Streptomyces FT coelicolor hypothetical protein SC4G6.36, 266 aa; fasta FT scores: opt: 519 Z-score: 588.1 E(): 4e-25; 34.470% FT identity in 264 aa overlap" FT /db_xref="GOA:Q9S2U7" FT /db_xref="InterPro:IPR012335" FT /db_xref="UniProtKB/TrEMBL:Q9S2U7" FT /protein_id="CAB51427.1" FT /translation="MDLGPGRRAAPPRFVLRGVSEKNRQGKRGAREKLAAEREKQRSRD FT KRRRALIVGASVVCVLGLAAVIGVVAANAGKDDGSESAGPVVAPSGAQGKDGLAIPVGE FT ESAKSTLTVWEDFRCPACKAFELAYRNTIHELTDAGQLKVEYHLATIIDGNMGGTGSRK FT AANAAACAQDAGKFPPYHDVLYDNQPPETDDAFADENKLLDLAGKVDGLDTTLFQECVK FT NGKHNSWVEKSNKAFQNGGFSGTPTVLLDGKNIYQDRSMTPAKLKQMVEDANK" FT CDS complement(85211..86026) FT /transl_table=11 FT /gene="SCO2036" FT /gene_synonym="SC4G6.05c" FT /gene_synonym="trpA" FT /product="tryptophan synthase alpha subunit" FT /note="SC4G6.05c, trpA, tryptophan synthase alpha subunit, FT len: 271aa; previously sequenced therefore identical FT (except for A>G conflict at first base) to TR:O68816 FT (EMBL:AF054585). Also similar to many others eg. FT SW:TRPA_THETH tryptophan synthase alpha chain from Thermus FT thermophilus (271 aa) fasta scores; opt: 711, z-score: FT 781.5, E(): 0, (47.6% identity in 248 aa overlap). Contains FT Pfam match to entry PF00290 trp_syntA, Tryptophan synthase FT alpha chain and Prosite match to PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign." FT /db_xref="GOA:O68816" FT /db_xref="HSSP:1GEQ" FT /db_xref="InterPro:IPR002028" FT /db_xref="UniProtKB/Swiss-Prot:O68816" FT /protein_id="CAB51428.1" FT /translation="MSGNVQLLNDTLAAAKSEGRAALIAYLPAGFPTVTGGIEAVKAAL FT DGGADVVEVGLPHSDPVLDGPVIQTADDIALRGGVRIADVMRTVREAHEATGKPILVMT FT YWNPIDRYGVERFTAELAEAGGAGCILPDLPVQESALWREHADKHGLATVFVVAPSSRD FT ARLAEITAVGSGFVYAASLMGVTGTRASVGAQAEDLVRRTRATTDTPVCVGLGVSNAAQ FT AAEVAGFADGVIVGSAFVKRMLDAPDDAAGLEGVRALAADLAKGVRGQA" FT misc_feature complement(85304..85390) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT misc_feature complement(85307..85963) FT /note="Pfam match to entry PF00290 trp_syntA, Tryptophan FT synthase alpha chain, score 270.60, E-value 2e-77." FT CDS complement(86023..87306) FT /transl_table=11 FT /gene="SCO2037" FT /gene_synonym="SC4G6.06c" FT /gene_synonym="trpB" FT /product="tryptophan synthase beta subunit" FT /note="SC4G6.06c, trpB, tryptophan synthase beta subunit, FT len: 427 aa; previously sequenced therefore identical to FT TR:O05625 (EMBL:AF054585). Also similar to SW:TRPB_CAUCR FT tryptophan synthase beta chain from Caulobacter crescentus FT (406 aa) fasta scores; opt: 1660, z-score: 1848.0, E(): 0, FT (61.2% identity in 397 aa overlap). Contains Pfam match to FT entry PF00247 trp_syntB, Tryptophan synthases, beta chain FT and Prosite match to PS00168 Tryptophan synthase beta chain FT pyridoxal-phosphate attachment site." FT /db_xref="GOA:O05625" FT /db_xref="HSSP:2WSY" FT /db_xref="InterPro:IPR006654" FT /db_xref="UniProtKB/Swiss-Prot:O05625" FT /protein_id="CAB51429.1" FT /translation="MPSNFFIPDPEGQVPSAEGYFGAFGGKFIPEALVAAVDEVAVEYD FT KAKSDPEFARELDDLLVHYTGRPSALTEVPRFAAEAGGARIFLKREDLNHTGSHKINNV FT LGQALLTKRMGKTRVIAETGAGQHGVATATACALFGLDCTIYMGEIDTRRQALNVARMR FT MLGAEVIAVKSGSRTLKDAINEAFRDWVANVDRTHYLFGTVAGPHPFPAMVRDFHRVIG FT VEARRQLLEQAGRLPDAAIACVGGGSNAIGLFHAFIPDADVRLIGCEPAGHGVETGEHA FT ATLTAGEPGILHGSRSYVLQDDEGQITEPYSISAGLDYPGIGPEHAYLKDSGRGEYRAV FT TDDAAMQALRLLSRTEGIIPAIESAHALAGALEVGRELGRDGLLVVNLSGRGDKDMDTA FT ARYFGLYDTDAEVAADGTGAAEIEGDAK" FT misc_feature complement(86098..87246) FT /note="Pfam match to entry PF00247 trp_syntB, Tryptophan FT synthases, beta chain, score 931.10, E-value 3e-276." FT misc_feature complement(87001..87030) FT /note="PS00168 Tryptophan synthase beta chain FT pyridoxal-phosphate attachment site." FT CDS complement(87421..87612) FT /transl_table=11 FT /gene="SCO2038" FT /gene_synonym="SC4G6.07c" FT /product="hypothetical protein" FT /note="SC4G6.07c, unknown, len: 63aa; previously sequenced FT therefore identical to TR:O68815 (EMBL:AF054585)." FT /db_xref="UniProtKB/TrEMBL:O68815" FT /protein_id="CAB51430.1" FT /translation="MTLPLVPARDPYARLARGCRPRGCRAPARRVHGRRVRYVIGDEPG FT QVNGMRWLKRPIRGAGLY" FT CDS complement(87633..88442) FT /transl_table=11 FT /gene="SCO2039" FT /gene_synonym="SC4G6.08c" FT /gene_synonym="trpC1" FT /product="indoleglycerol phosphate synthase" FT /note="SC4G6.08c, trpC1, indoleglycerol phosphate synthase, FT len: 269 aa; previously sequenced therefore identical to FT TR:O68814 (EMBL:AF054585). Also similar to many others eg. FT SW:TRPC_AZOBR trpC, indoleglycerol phosphate synthase from FT Azospirillum brasilense (262 aa) fasta scores; opt: 589, FT z-score: 655.0, E(): 3.7e-29, (44.4% identity in 259 aa FT overlap). Contains Pfam match to entry PF00218 IGPS, FT Indole-3-glycerol phosphate synthases and Prosite match to FT PS00614 Indole-3-glycerol phosphate synthase signature." FT /db_xref="GOA:O68814" FT /db_xref="HSSP:1J5T" FT /db_xref="InterPro:IPR001468" FT /db_xref="UniProtKB/Swiss-Prot:O68814" FT /protein_id="CAB51431.1" FT /translation="MSVLDEIIDGVRADLAERQARVSLDELKERAAKARPAKDGVAALR FT GDGVKVICEVKRSSPSKGALAAIADPAGLAADYEAGGAAVISVLTEERRFGGSLADLDS FT VRARVDIPVLRKDFIVTSYQLWEARAHGADLVLLIVAALEQPALESLIERAESIGLTPL FT VEVHDEDEVERAVDAGAKVIGVNARNLKTLEVDRGTFERVAPEIPAHIVKVAESGVRGP FT HDLIAYANEGADAVLVGESLVTGRDPKTAVSDLVAAGEHPALRHGRS" FT misc_feature complement(87678..88436) FT /note="Pfam match to entry PF00218 IGPS, Indole-3-glycerol FT phosphate synthases, score 365.60, E-value 5.3e-106." FT misc_feature complement(88248..88292) FT /note="PS00614 Indole-3-glycerol phosphate synthase FT signature." FT CDS complement(88560..89006) FT /transl_table=11 FT /gene="SCO2040" FT /gene_synonym="SC4G6.09c" FT /product="putative membrane protein" FT /note="SC4G6.09c, possible membrane protein, len: aa; FT similar to TR:O06133 (EMBL:Z95554) hypothetical protein FT from Mycobacterium tuberculosis (132 aa) fasta scores; opt: FT 245, z-score: 301.1, E(): 1.9e-09, (36.7% identity in 128 FT aa overlap). Contains possible membrane spanning FT hydrophobic regions" FT /db_xref="UniProtKB/TrEMBL:Q9S2U5" FT /protein_id="CAB51432.1" FT /translation="MDVESGKPGRTSIPLPRGAALRLAVPAGVLAAVAGAFAYVGSVDP FT YEPGHYPVCPLLRFTGVYCPGCGGLRSAHAFVHGDLTAALHANAPAVLAYLGFAVLWTV FT WVIRTARGRPVRVDLGPVHLWTLGALLLVFTVVRNLPFGGWLLP" FT CDS complement(89109..89360) FT /transl_table=11 FT /gene="SCO2041" FT /gene_synonym="SC4G6.10c" FT /product="putative membrane protein" FT /note="SC4G6.10c, possible membrane protein, len: 83aa; FT Contains possible membrane spanning hydrophobic regions." FT /db_xref="UniProtKB/TrEMBL:Q9S2U4" FT /protein_id="CAB51433.1" FT /translation="MAGSSHGHTPAAWTGVIIAFIGFCIAGMFMVAAQPWGFWAGMAVV FT LLGGVVGYIMKMMGLGQPKQNHPVHQVAGERAEAGAKG" FT CDS complement(89505..90140) FT /transl_table=11 FT /gene="SCO2042" FT /gene_synonym="SC4G6.11c" FT /product="putative membrane protein" FT /note="SC4G6.11c, possible membrane protein, len: 211aa; FT similar to TR:O06128 (EMBL:Z95554) hypothetical protein FT from Mycobacterium tuberculosis (235 aa) fasta scores; opt: FT 155, z-score: 174.0, E(): 0.023, (29.9% identity in 224 aa FT overlap). Contains possible membrane spanning hydrophobic FT regions." FT /db_xref="InterPro:IPR019051" FT /db_xref="UniProtKB/TrEMBL:Q9S2U3" FT /protein_id="CAB51434.1" FT /translation="MEYVTAVPHPRTPAAGPARAGRRSLAVALLCGALGAAVALLATRQ FT EWAEGTATVAGGAFTLTAKGSDVTGVPASLAIVGLAALVAVFAVRRAGRFAVAALLALS FT GAGTVAAALAGASDSSALDDQAAKAAGDTSATVDALSHTAWPYVAAVGGALLLLAGLLA FT LRYGRQWPAMSGRYERSGAPRRRPQTVDPDRPEDLWKAIDRGEDPTSA" FT CDS complement(90224..91732) FT /transl_table=11 FT /gene="SCO2043" FT /gene_synonym="SC4G6.12c" FT /gene_synonym="trpE3" FT /product="putative anthranilate synthase component I" FT /note="SC4G6.12c, trpE3, probable anthranilate synthase FT component I, len: 502aa; similar to many eg. SW:TRPE_ARTGO FT anthranilate synthase component I from Arthrobacter FT globiformis (531 aa) fasta scores; opt: 1921, z-score: FT 2150.9, E(): 0, (60.6% identity in 500 aa overlap). FT Contains Pfam match to entry PF00425 chorismate_bind, FT chorismate binding enzyme." FT /db_xref="GOA:Q9S2U2" FT /db_xref="HSSP:1K0E" FT /db_xref="InterPro:IPR019999" FT /db_xref="UniProtKB/TrEMBL:Q9S2U2" FT /protein_id="CAB51435.1" FT /translation="MDVTHDMDLDTFRKLAADRRVIPVSRKLLADGDTPVALYRKLAAS FT RPGTFLLESAENGRSWSRYSFVGVRSAATLTEKDGQAHWQGTPPVGVPTDGDPLAALRA FT TVEALHTPRDLAHDLGLPPFTGGMVGYLGYDIVRRLEKVGPGERDDLKLPELTMLLTSD FT LAVMDHWEGSVLLIANAINHNDLETGVDEAYADAIARLDVMEADLTRAVAQPPAALPPS FT ELPEYTALWGGPDFQDAVEDIKERIRAGEAFQVVPSQRFETPCTASALDVYRVLRATNP FT SPYMYLLRLDGFDVVGSSPEALVKVEDGRAMVHPIAGTRPRGATPREDQSLADELLADP FT KERAEHLMLVDLGRNDLGRVCEPGSVEVVDFMSVERYSHVMHIVSTVTGRVAPGRTAFD FT VLTACFPAGTLSGAPKPRALQIIDELEPSRRGLYGGCVGYLDFAGDSDTAIAIRTALLR FT DGTAYVQAGAGVVADSDPVAEDTECRNKAAAVLRAVHTANRLAQ" FT misc_feature complement(90251..91039) FT /note="Pfam match to entry PF00425 chorismate_bind, FT chorismate binding enzyme, score 533.90, E-value 1.1e-156." FT CDS complement(91744..92130) FT /transl_table=11 FT /gene="SCO2044" FT /gene_synonym="SC4G6.13c" FT /product="putative phosphoribosyl-AMP cyclohydrolase" FT /note="SC4G6.13c, possible phosphoribosyl-AMP FT cyclohydrolase, len: 128aa; similar to but shorter than FT many eg. SW:HIS2_ECOLI phosphoribosyl-AMP cyclohydrolase FT from Escherichia coli (203 aa) fasta scores; opt: 343, FT z-score: 429.1, E(): 1.4e-16, (52.7% identity in 93 aa FT overlap). Also similar to SW:HIS3_MYCTU phosphoribosyl-AMP FT cyclohydrolase from Mycobacterium tuberculosis (115 aa) FT fasta scores; opt: 471, z-score: 588.3, E(): 1.9e-25, FT (64.2% identity in 109 aa overlap)." FT /db_xref="GOA:Q9S2U1" FT /db_xref="InterPro:IPR002496" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2U1" FT /protein_id="CAB51436.1" FT /translation="MTSSSPTGGGPGRPSALAPEIADRLKRSADGLLPAIAQQYDTGEV FT LMLGWMDDEALHRTLTTGRCTYWSRSRGEYWVKGDTSGHFQWVKSVALDCDADTVLVKV FT DQVGAACHTGTRTCFDTDVLLADQ" FT CDS 92212..92847 FT /transl_table=11 FT /gene="SCO2045" FT /gene_synonym="SC4G6.14" FT /product="conserved hypothetical protein" FT /note="SC4G6.14, unknown, len: 211aa; similar to TR:P95285 FT (EMBL:Z84498) hypothetical protein from Mycobacterium FT tuberculosis (214 aa) fasta scores; opt: 416, z-score: FT 500.9, E(): 1.4e-20, (39.8% identity in 206 aa overlap)." FT /db_xref="InterPro:IPR017519" FT /db_xref="UniProtKB/TrEMBL:Q9S2U0" FT /protein_id="CAB51437.1" FT /translation="MSTFAKRERLLLADLLETAGPDAPTLCEGWRTRDLAAHVVVRERR FT PDAAGGALIKPLASRLHRVREEYGAKPYEELLQLIRTGPPRFSPFQLKQVDEAANTVEF FT YVHTEDVRRAQDDWSPRELDPVFQDALWSRLERVARLMGRGIPTGLVLRRPNGQTTVAH FT RGTPVVTATGEPSELLLFAYGRQGAAKVELEGEENAIAKLRETKQLGI" FT CDS complement(92858..94012) FT /transl_table=11 FT /gene="SCO2046" FT /gene_synonym="SC4G6.15c" FT /product="putative integral membrane efflux protein" FT /note="SC4G6.15c, possible integral membrane efflux FT protein, len: 384aa; similar to many egs. TR:O31137 FT (EMBL:AF030344) TetV, tetracycline resistance determinant FT from Mycobacterium smegmatis (419 aa) fasta scores; opt: FT 446, z-score: 465.6, E(): 1.3e-18, (27.3% identity in 381 FT aa overlap) and TR:CAB41206 (EMBL:AL049661) putative FT integral membrane efflux protein from Streptomyces FT coelicolor (500 aa) fasta scores; opt: 416, z-score: 433.8, FT E(): 7.7e-17, (32.8% identity in 375 aa overlap). Contains FT possible membrane spanning hydrophobic regions." FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9S2T9" FT /protein_id="CAB51438.1" FT /translation="MLGDSVFFLALSWAAVRQGSPAEAGIVTAVSAVPRALLMLGGGVV FT VDRLGPRRVVIGSDAVRCAAVLTVAALLFATDPGLWLLALLALVFGGVDALFMPAVGAL FT PARITAKDQLARVQGMRGLAVRLSSVVGAPLGGLGVALGGAAAAFALAGVLIAVSVPLL FT VSVRMRELPPDDTATAEGGTAWRDLRDGLRYIRRHRVLGPLMLVIALGDLGFVGPLNIG FT LTLLADERGWGASGMGWVLAGFGAGAGTAALLLTVRGRVPHAGYVVAGALVPGAVAIGA FT LAQAPALPVAVGTALLIGLLAGLSGALCGALLQTQSAPALLGRVTAVSGIVSLGIAPLS FT MPLSAAAIGLWGTGPVFAVSAVVCGLGGVVALCAPGVRRAELPK" FT CDS complement(94122..94709) FT /transl_table=11 FT /gene="SCO2047" FT /gene_synonym="SC4G6.16c" FT /product="putative DNA-binding protein" FT /note="SC4G6.16c, possible DNA-binding protein, len: 195aa; FT contains helix-turn-helix motif (+3.18 SD) 37-58aa." FT /db_xref="GOA:Q9S2T8" FT /db_xref="InterPro:IPR001845" FT /db_xref="UniProtKB/TrEMBL:Q9S2T8" FT /protein_id="CAB51439.1" FT /translation="MPRQENHPITDLGTLKALAHPLRMQLYRGLCVARTATASQLAEQV FT DEAVSLVSYHLRKLAEHGLVEQADPQSADGRERWWQPSSDGVSIRDENFRDAPERAAAH FT LAATRLFHEQRADLYRRYLDERPTWGPEWNSAAPDNESLLRLTPAELGELGEELLALAK FT KYDEKGRAAEAAGDTEARENVALHVYGFPFRV" FT stem_loop 94728..94769 FT /note="perfect inverted repeat with 6 base potential loop." FT CDS complement(94793..95548) FT /transl_table=11 FT /gene="SCO2048" FT /gene_synonym="SC4G6.17c" FT /product="putative hisF, cyclase" FT /note="SC4G6.17c, hisF, cyclase, len: 251aa; highly similar FT to many eg. SW:HIS6_AZOBR HisF protein (cyclase) from FT Azospirillum brasilense (261 aa) fasta scores; opt: 1067, FT z-score: 1189.3, E(): 0, (64.8% identity in 250 aa FT overlap). Contains Pfam match to entry PF00977 FT His_biosynth, Histidine biosynthesis protein." FT /db_xref="GOA:Q9S2T7" FT /db_xref="HSSP:1GPW" FT /db_xref="InterPro:IPR004651" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2T7" FT /protein_id="CAB51440.1" FT /translation="MTLAVRVIPCLDVDNGRVVKGVNFQNLRDAGDPVEMAKVYDAEGA FT DELTFLDITASSGNRETTYDVVRRTAEQVFIPLTVGGGVRTAEDVDKLLRAGADKVGVN FT TAAIARPDLIREIAERFGRQVLVLSVDARRTEAGTFEVTTHGGRRGTGIDAVEWAHRAA FT ELGAGEILLNSMDADGTKDGYDLEMLAAVRKHVSVPVIASGGAGSLAHFAPAVEAGADA FT VLAASVFHFGDLRIGEVKTTLREAGHPVR" FT misc_feature complement(94820..95536) FT /note="Pfam match to entry PF00977 His_biosynth, Histidine FT biosynthesis protein, score 420.50, E-value 1.5e-122." FT CDS complement(95545..95949) FT /transl_table=11 FT /gene="SCO2049" FT /gene_synonym="SC4G6.18c" FT /product="conserved hypothetical protein" FT /note="SC4G6.18c, conserved hypothetical protein, len: FT 134aa; previously sequenced therefore almost identical to FT SW:YHI2_STRCO. Also similar to many others eg. TR:O07205 FT (EMBL:Z96072) hypothetical protein from Mycobacterium FT tuberculosis (142 aa) fasta scores; opt: 225, z-score: FT 300.2, E(): 2.1e-09, (34.1% identity in 123 aa overlap)." FT /db_xref="InterPro:IPR006175" FT /db_xref="UniProtKB/Swiss-Prot:P16251" FT /protein_id="CAB51441.1" FT /translation="MTSEAVRRVQSGSPWEESFGFARAVAAGDRVIVAGTTAFKGDMLY FT GEGDPYEQTKVAFGTAVEAIAEFGLGIESVIRTRVCLAHSRDVDAVGRAHKELFDSVRP FT VTTLLVVQGFIDSRVLVSVEVEAYRGAVDS" FT CDS complement(95966..96688) FT /transl_table=11 FT /gene="SCO2050" FT /gene_synonym="SC4G6.19c" FT /gene_synonym="hisA" FT /product="phosphoribosylformimino-5-aminoimidazole FT carboxamide ribotide isomerase" FT /note="SC4G6.19c, hisA, FT phosphoribosylformimino-5-aminoimidazole carboxamide FT ribotide isomerase, len: 240aa; previously sequenced FT therefore identical to SW:HIS4_STRCO. Contains Pfam match FT to entry PF00977 His_biosynth, Histidine biosynthesis FT protein." FT /db_xref="GOA:P16250" FT /db_xref="InterPro:IPR010188" FT /db_xref="PDB:1VZW" FT /db_xref="UniProtKB/Swiss-Prot:P16250" FT /protein_id="CAB51442.1" FT /translation="MSKLELLPAVDVRDGQAVRLVHGESGTETSYGSPLEAALAWQRSG FT AEWLHLVDLDAAFGTGDNRALIAEVAQAMDIKVELSGGIRDDDTLAAALATGCTRVNLG FT TAALETPEWVAKVIAEHGDKIAVGLDVRGTTLRGRGWTRDGGDLYETLDRLNKEGCARY FT VVTDIAKDGTLQGPNLELLKNVCAATDRPVVASGGVSSLDDLRAIAGLVPAGVEGAIVG FT KALYAKAFTLEEALEATS" FT misc_feature complement(95972..96679) FT /note="Pfam match to entry PF00977 His_biosynth, Histidine FT biosynthesis protein, score 170.10, E-value 3.7e-47." FT CDS complement(96706..97374) FT /transl_table=11 FT /gene="SCO2051" FT /gene_synonym="SC4G6.20c" FT /gene_synonym="hisH" FT /product="hisH, amidotransferase" FT /note="SC4G6.20c, hisH, amidotransferase, len: 222aa; FT previously sequenced therefoer identical to SW:HIS5_STRCO. FT Contains Pfam match to entry PF00117 GATase, Glutamine FT amidotransferase class-I and Prosite match to PS00442 FT Glutamine amidotransferases class-I active site." FT /db_xref="GOA:P16249" FT /db_xref="HSSP:1GPW" FT /db_xref="InterPro:IPR016226" FT /db_xref="UniProtKB/Swiss-Prot:P16249" FT /protein_id="CAB51443.1" FT /translation="MTAAVPAGATGRAKKVVVFDYGFGNVRSAERALARAGADVEITRD FT YDKAMNADGLLVPGVGAFAACMEGLKAARGDWIVDRRLSGGRPVMGICVGMQILFSRGI FT EHDVEAEGLDEWPGTVGPLEADVVPHMGWNTVEAPADSQLFAGLDADARFYFVHSYAVH FT EWTQESHNPLIAEPRVTWSTHGKPFVAAVENGALWATQFHPEKSGDAGAQLLTNWIETL FT " FT misc_feature complement(96712..97332) FT /note="Pfam match to entry PF00117 GATase, Glutamine FT amidotransferase class-I, score 168.00, E-value 1.5e-46." FT misc_feature complement(97078..97113) FT /note="PS00442 Glutamine amidotransferases class-I active FT site." FT CDS complement(97539..98132) FT /transl_table=11 FT /gene="SCO2052" FT /gene_synonym="SC4G6.21c" FT /gene_synonym="hisB" FT /product="imidazoleglycerol-phosphate dehydratase" FT /note="SC4G6.21c, hisB, imidazoleglycerol-phosphate FT dehydratase, len: 197aa; previously sequenced therefore FT identical to SW:HIS7_STRCO. Contains Pfam match to entry FT PF00475 IGPD, Imidazoleglycerol-phosphate dehydratase and FT Prosite matches to PS00955 Imidazoleglycerol-phosphate FT dehydratase signature 2 and PS00954 FT Imidazoleglycerol-phosphate dehydratase signature 1." FT /db_xref="GOA:P16247" FT /db_xref="InterPro:IPR000807" FT /db_xref="UniProtKB/Swiss-Prot:P16247" FT /protein_id="CAB51444.1" FT /translation="MSRVGRVERTTKETSVLVEIDLDGTGKTDIATGVGFYDHMLDQLG FT RHGLFDLTVKTDGDLHIDSHHTIEDTALALGAAFRQALGDKVGIYRFGNCTVPLDESLA FT QVTVDLSGRPYLVHTEPENMAPMIGEYDVTMTRHILESFVAQAQVALHVHVPYGRNAHH FT IVECQFKALARALRYASERDPRAAGILPSTKGAL" FT misc_feature complement(97602..98039) FT /note="Pfam match to entry PF00475 IGPD, FT Imidazoleglycerol-phosphate dehydratase, score 369.00, FT E-value 6.2e-126." FT misc_feature complement(97623..97661) FT /note="PS00955 Imidazoleglycerol-phosphate dehydratase FT signature 2." FT misc_feature complement(97908..97949) FT /note="PS00954 Imidazoleglycerol-phosphate dehydratase FT signature 1." FT CDS complement(98129..99238) FT /transl_table=11 FT /gene="SCO2053" FT /gene_synonym="SC4G6.22c" FT /gene_synonym="hisC1" FT /product="histidinol-phosphate aminotransferase" FT /note="SC4G6.22c, hisC1, histidinol-phosphate FT aminotransferase, len: 369aa; previously sequenced FT therefore identical to SW:HIS8_STRCO. Contains Pfam match FT to entry PF00222 aminotran_2, Aminotransferases class-II FT and Prosite match to PS00599 Aminotransferases class-II FT pyridoxal-phosphate attachment site." FT /db_xref="GOA:P16246" FT /db_xref="HSSP:1FG7" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/Swiss-Prot:P16246" FT /protein_id="CAB51445.1" FT /translation="MTFGIDDLPVRDELRGKSPYGAPQLDVPVRLNTNENPYPLPEALV FT ERIAERVREAARDLNRYPDRDAVELRTQLARYLTDTSGHPLDVSNVWAANGSNEVIQQL FT LQTFGGPGRTAIGFEPSYSMHGLIARGTGTGWISGPRHEDFTIDVPAATRAIDEHRPDV FT VFITTPNNPTGTAVPAETVLALYEAAQAAKPSMVVVDEAYIEFSHGASLLPLLDGRPNL FT VVSRTMSKAFGAAGLRLGYLAAHPAVVDAVQLVRLPYHLSAVTQATALAALEHTDTLLK FT YVEQLKTERDRLVAELRAIGYAVTESDANFVQFGRFADSHATWRKILDRGVLVRDNGVP FT GWLRVTAGTPEENDAFLDAVREVKKEQHT" FT misc_feature complement(98207..98986) FT /note="Pfam match to entry PF00222 aminotran_2, FT Aminotransferases class-II, score 335.40, E-value 6.6e-97." FT misc_feature complement(98531..98560) FT /note="PS00599 Aminotransferases class-II FT pyridoxal-phosphate attachment site." FT CDS complement(99235..100560) FT /transl_table=11 FT /gene="SCO2054" FT /gene_synonym="SC4G6.23c" FT /gene_synonym="hisD" FT /product="histidinol dehydrogenase" FT /note="SC4G6.23c, hisD, histidinol dehydrogenase, len: FT 441aa; previously sequenced therefore identical to FT SW:HISX_STRCO. Contains Pfam match to entry PF00815 FT Histidinol_dh, Histidinol dehydrogenase and Prosite match FT to PS00611 Histidinol dehydrogenase signature." FT /db_xref="GOA:P16245" FT /db_xref="HSSP:1K75" FT /db_xref="InterPro:IPR012131" FT /db_xref="UniProtKB/Swiss-Prot:P16245" FT /protein_id="CAB51446.1" FT /translation="MISRIDLRGDALPEGPALRDLLPRADFDVSVALEKVRPICEAVHH FT RGDAALIDFTEQFDGVRLERVRVPAEELTRALEGLDPEVRAALEESIRRARLVHREQRR FT ATHTTQVVPGGSVTEKWVPVERVGLYVPGGRSVYPSSVVMNVVPAQEAGVGSIALASPA FT QAEFGGIPHPTILAACALLGVDEVYAAGGATAVAMFAYGTESCPPANMVTGPGNIWVAA FT AKRFFTGKIGIDAEAGPTEIAVLADSTADPVHVASDLISQAEHDPLAAAVLVTDSAELA FT DAVEKELQPQVEATKHIEDRIRPALAGRQSAIVLVDGLDEGLRVVDAYGAEHLEIQTAD FT AAAVADRVKNAGAIFVGPWAPVSLGDYAAGSNHVLPTGGCACHSSGLSVQSFLRGIHIV FT DYTRDALAEVARHVVTLAEAEDLPAHGAAIKARFEWKVPESK" FT misc_feature complement(99259..100509) FT /note="Pfam match to entry PF00815 Histidinol_dh, FT Histidinol dehydrogenase, score 880.70, E-value 4.4e-261." FT misc_feature complement(99766..99864) FT /note="PS00611 Histidinol dehydrogenase signature." FT CDS 100760..102337 FT /transl_table=11 FT /gene="SCO2055" FT /gene_synonym="SC4G6.24" FT /product="hypothetical protein" FT /note="SC4G6.24, unknown, len: 525 aa; previously sequenced FT but annotated as two seperate hypothetical CDSs TR:Q53930 FT and TR:Q53931 (EMBL:X64420)) suggesting a sequence error FT which lead to a frameshift. Amino acid and codon usage FT plots support a single CDS. Also similar to TR:O88013 FT (EMBL:AL031107) hypothetical protein from Streptomyces FT coelicolor (527 aa) fasta scores; opt: 593, z-score: 699.2, FT E(): 1.3e-31, (36.0% identity in 545 aa overlap). Contains FT possible hydrophobic membrane spanning region at C-terminal FT domain" FT /db_xref="UniProtKB/TrEMBL:Q9S2T4" FT /protein_id="CAB51447.1" FT /translation="MTEGAGHRDGELPDDLTTAEAGMWQAFRNGSVYDLSSGDALVDDP FT HGGHPWGPERTVRARVVCWLLLDGPPALAGRVSSLQLVGVRISDTMDLAGGTVVPYVEL FT RRCRFEREVLLPETRFTTVRLVDCAVPRLEAARLHTEGDLHLPRSRFPGGIRLTDAQIG FT TDLLLNQAIVHRDRSGRSIAADGMTVGQDLQAEMLESHGEVSLRSAQVGVSLSLRGARL FT LNPYTRHALNAPQLTVERTLYLTPAGLGSPLLRGTTPAQGTRIQHFECEGGVRLDDGRF FT GDALDLEHARFTFTDDQELSLRRVQTPELRFLGERPARGRVVLSGARVVNLMDRADSWP FT GPGRLHMGGFAYENLVPRGPFPLAKRLRWVGAATAEYHPEPYERLAAVLRAGGEDEDAR FT EVLLAKHRRRRESLPVAAKLVGYAQDWTVAYGYRPGRAAVWMAVLWAAGSLAFARADPP FT PLKSGEHPDWNPALFALDLLLPVIDLGQAGSWQLHSGWQWLSTALVLLGWVLATTVAAG FT ATRLLRRS" FT CDS 102605..103735 FT /transl_table=11 FT /gene="SCO2056" FT /gene_synonym="SC4G6.25" FT /product="hypothetical protein" FT /note="SC4G6.25, unknown, len: 376aa;" FT /db_xref="UniProtKB/TrEMBL:Q9S2T3" FT /protein_id="CAB51448.1" FT /translation="MAEPRPHNHPEPSAVVLAMLRAFLRTAAARARSRAPRPAQDDDVL FT LDAPDDRLAPALVAAAHGEHGPAARLLAGTRHDAEWDHRDRYATRLAAFARFRSEWLDT FT WRATAPDDPDALLVAARLAVHRHWDSPARTELLRQVIPSVVAAAETAGPADPVPWRTAL FT DAARGAGAEHAEFERLWEQAVRRSPHHYGSHVAALEYLAAASSDGHGECLDFAETAAQE FT APEEALVRALPLHAAFTCLTATGTGTGTDARTGGATTAAVRTHRPRLDAAADRAITLSA FT AHPAADPWAAELRNLLVYVLVRLERHQDAAEQLRLTGPYVTSFPWDRDTDDPLGGFLRV FT RADVRAHPGEAAAATGTAAPGRPRNGYGERVRPGDH" FT CDS 103747..104487 FT /transl_table=11 FT /gene="SCO2057" FT /gene_synonym="SC4G6.26" FT /product="hypothetical protein" FT /note="SC4G6.26, unknown, len: 246 aa; similar to TR:Q55701 FT (EMBL:D64000) hypothetical protein from Synechocystis sp. FT strain PCC6803 (214 aa) fasta scores; opt: 158, z-score: FT 192.8, E(): 0.0021, (32.6% identity in 224 aa overlap). FT Also some simliarity to the N-terminal region of many FT ATP-dependent proteases eg. SW:LON_ECOLI Lon protease from FT Escherichia coli (784 aa) fasta scores; opt: 152, z-score: FT 176.8, E(): 0.016, (24.6% identity in 228 aa overlap)." FT /db_xref="GOA:Q9S2T2" FT /db_xref="InterPro:IPR003111" FT /db_xref="UniProtKB/TrEMBL:Q9S2T2" FT /protein_id="CAB51449.1" FT /translation="MTTVRLPLFPLNSVLFPGLVLPLNIFEERYRAMMRELLKTPEDEP FT RRFAVVAIRDGFEVAQTAPGLPDPTATLERGPTAGFGTDPLKAFHKVGCVADAATVRER FT ADGTFEVLATGTTRMRLLSVEASGPFLTAELEPLPEEPGDEAGALAEGVLRSFRQYQKR FT LAGARERSLATGADLPDEPGVVSYLVAAAMMLDTPTKQRLLQAPDTASRLRDELKLLRS FT ETAIIRTLPSLPAQELTRGPTSLN" FT CDS 104501..105010 FT /transl_table=11 FT /gene="SCO2058" FT /gene_synonym="SC4G6.27" FT /product="putative transcriptional regulatory protein" FT /note="SC4G6.27, possible transcriptional regulatory FT protein, len: 169 aa; similar to many e.g. TR:Q51388 FT (EMBL:U49666) proposed regulatory protein from the glycerol FT metabolism cluster in Pseudomonas aeruginosa (156 aa) fasta FT scores; opt: 546, z-score: 627.8, E(): 1.2e-27, (59.7% FT identity in 154 aa overlap). Contains possible FT helix-turn-helix motif (+2.63 SD) 43-64 aa. Contains FT possible N-terminal region signal peptide sequence" FT /db_xref="GOA:Q9S2T1" FT /db_xref="HSSP:1DBX" FT /db_xref="InterPro:IPR007214" FT /db_xref="UniProtKB/TrEMBL:Q9S2T1" FT /protein_id="CAB51450.1" FT /translation="MAKKPSKAKKQQPGGTPATVALTAAGVTYTVHAYEHDPAHPSYGE FT EAAEAMGVSPERVFKTLVADVDGALTVAVVPVAGQLDLKALAAAVGGKRAAMADPALAE FT RTTGYVRGGISPLGQRKRLATVLDASASGHATICVSAGRRGLEVELSPDDLARLTDAVL FT APIGRA" FT CDS complement(105142..105858) FT /transl_table=11 FT /gene="SCO2059" FT /gene_synonym="SC4G6.28c" FT /product="putative membrane protein" FT /note="SC4G6.28c, possible membrane protein, len: 238aa; FT Contains possible membrane spanning hydrophobic regions." FT /db_xref="UniProtKB/TrEMBL:Q9S2T0" FT /protein_id="CAB51451.1" FT /translation="MTAPLTPPPPPNERPSYQGGPVPPPVGAHAVGAAPGGSHDPYGTY FT GEQDGPGMLTEVRQAAVTALAVALSGALLGVLWWKLAPSVPLVGEILDDSWVVYLKDSE FT GEQAIGVDGTFTLLALAFGALSAVVVFLLRRRGGVPLVVALGVGGLLGSLLAWRLGVWL FT GPAQDVIAHAKDVGKGVTFSAPLKLGAKGALLAWSLAALVVHLGLTGLFGPRDPEPDPW FT PAPGQYPSAPYGDKPA" FT CDS complement(105893..106813) FT /transl_table=11 FT /gene="SCO2060" FT /gene_synonym="SC4G6.29c" FT /product="putative integral membrane transport protein" FT /note="SC4G6.29c, possible integral membrane transport FT protein, len: 306aa; weakly similar to many eg. TR:CAB42664 FT (EMBL:AL049819) putative integral membrane protein from FT Streptomyces coelicolor (266 aa) fasta scores; opt: 163, FT z-score: 184.2, E(): 0.0061, (25.3% identity in 273 aa FT overlap). Contains possible membrane spanning hydrophobic FT regions. Location directly downstream of a possible ABC FT transport ATP-binding protein sueggsts a transport FT function." FT /db_xref="GOA:Q9S2S9" FT /db_xref="InterPro:IPR013525" FT /db_xref="UniProtKB/TrEMBL:Q9S2S9" FT /protein_id="CAB51452.1" FT /translation="MRTPAAASVPVGASAPARATASNDPSEGELRDVSVVPADALRGAA FT PAAEGRRAAGPAALGPKARLWPSLVAVYRAQLSRARVARIPLLFVATFQSVGIMILMRG FT VVDGGGEARAVVAGSAVLVVAFVALNLLAQYFGQLRASGGLDHYATLPVPPAAVVLGAA FT GAYASFTVPGTVVTAVFGCLLFGLPMTHLWVLVAVIPLAGAALAGLGAALGLLAPRPEF FT ATLLGQLGMSAALLLGVLPPERMPQVVRLARDLLPSTYGVEAFARTFGERPDWGFVLGD FT LAVCAAVGVISLAVATWAYRRAAVR" FT CDS complement(106825..107799) FT /transl_table=11 FT /gene="SCO2061" FT /gene_synonym="SC4G6.30c" FT /product="putative ABC transport ATP-binding subunit" FT /note="SC4G6.30c, possible ABC transport ATP-binding FT subunit, len: 324aa; similar to many eg. TR:Q53716 FT (EMBL:L06249) ATP-binding protein from Streptomyces FT antibioticus (325 aa) fasta scores; opt: 611, z-score: FT 658.7, E(): 2.3e-29, (39.4% identity in 310 aa overlap). FT Also similar to TR:CAB42771 (EMBL:AL049841) from FT Streptomyces coelicolor (315 aa) fasta scores; opt: 599, FT z-score: 646.2, E(): 1.1e-28, (40.9% identity in 291 aa FT overlap). Contains Pfam match to entry PF00005 ABC_tran, FT ABC transporter and Prosite matches to PS00211 ABC FT transporters family signature and PS00017 ATP/GTP-binding FT site motif A (P-loop)." FT /db_xref="GOA:Q9S2S8" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9S2S8" FT /protein_id="CAB51453.1" FT /translation="MCVVRSLTKTYPAVRGRRGVPAAPEVRATDDVTLDIRRGEIFGLL FT GPNGAGKSTLVRQLTGLMRPDGGSVEILGHDIVRHPERAARILAYLGQESSALDELTVS FT LAAETTGRLRGLEVRRARAERDAVLEELGLTGLAGRPIKKLSGGQRRLACFAAALVGER FT PLLVLDEPTTGMDPVARRAVWSAVDRRRAEHGATVLLVTHNVIEAETVLDRVAVLDRGR FT VIACDTPAGLKEQVAGEVRVDLVWRESAPLNVPEVAALRDRVVESGRRWTLRLAPEEAR FT AVVATVTGGAAFAALDDFTLATPSLEDVYLALGGAARQGLVRT" FT misc_feature complement(107137..107685) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 173.00, E-value 4.8e-48." FT misc_feature complement(107323..107367) FT /note="PS00211 ABC transporters family signature." FT misc_feature complement(107641..107664) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS complement(107967..109178) FT /transl_table=11 FT /gene="SCO2062" FT /gene_synonym="SC4G6.31c" FT /product="hypothetical protein" FT /note="SC4G6.31c, unknown, len: 403aa;" FT /db_xref="InterPro:IPR002790" FT /db_xref="UniProtKB/TrEMBL:Q9S2S7" FT /protein_id="CAB51454.1" FT /translation="MDRCIVLVDAGYLLGAAASLLAGEPSRSRITVDHAALIQGLRDRA FT ESDTQQPLLRIYWFDGAPDRVPQPEHRRLRVMPRVTVRLGALTRSDGRWAQKGVDAAMH FT AELTELARNRACSDVVLVTGDGDLLPGMMAAKEHGVAVHLWAVQAADGDYNQSEDLVAE FT ADERRVLDRTWITKAVRAKELGGICAPPPVPRPEIAAILSAPLPESALSAAQRPAETPE FT HPTTAAAGPTGTEERVPPAKGVPTPKDLAALRAPGAHPAPQPANATLRWSSDKGWVDRP FT AAEPSEAATLPTLAQLTTAEQRWADREEDITTVGGDPYEVGQVFARRWLERLGDHGHLQ FT KLSGMYPRIPHRVDGELLRYAARFGLLAHKDDQIDEHDRYAIRAGFWREIDVRTATERT FT PAAE" FT CDS 109403..109570 FT /transl_table=11 FT /gene="SCO2063" FT /gene_synonym="SC4G6.32" FT /product="putative small hydrophilic protein" FT /note="SC4G6.32, possible small hydrophilic protein, len: FT 55 aa" FT /db_xref="UniProtKB/TrEMBL:Q9S2S6" FT /protein_id="CAB51455.1" FT /translation="MAKNKNNRDRKHPQAERSPQAAESAVLDREEQHSPQLTTPGDAAA FT RKRNKRFGHN" FT CDS complement(109637..113176) FT /transl_table=11 FT /gene="SCO2064" FT /gene_synonym="SC4G6.33c" FT /gene_synonym="dnaE" FT /product="DNA polymerase III alpha chain" FT /note="SC4G6.33c, dnaE, probable DNA polymerase III alpha FT chain, len: 1179 aa; similar to many e.g. SW:DP3A_ECOLI FT DnaE, DNA polymerase III alpha chain (1160 aa) fasta FT scores; opt: 2252, z-score: 2561.2, E(): 0, (36.1% identity FT in 1193 aa overlap)." FT /db_xref="GOA:Q9Z618" FT /db_xref="InterPro:IPR004805" FT /db_xref="UniProtKB/Swiss-Prot:Q9Z618" FT /protein_id="CAB51456.1" FT /translation="MSKPPFTHLHVHTQYSLLDGAARLKDMFDACNEMGMSHIAMSDHG FT NLHGAYDFFHSAKKAGVTPIIGIEAYVAPESRRNKRKIQWGQPHQKRDDVSGSGGYTHK FT TMWATNSKGLHNLFRLSSDAYAEGWLQKWPRMDKETISQWSEGIVASTGCPSGEVQTRL FT RLGHFDEALKAAADYQDIFGKDRYFLELMDHGIEIEHRVRDGLLEIGRKLGIPPLVTND FT SHYTYAHEATAHDALLCIQTGKNLSDPDRFRFDGTGYYLKSTDEMYAIDSSDAWQEGCA FT NTRLIAEMIDTTGMFEKRDLMPKFDIPEGFTEITWFQEEVRRGMERRFPGGVPEDRQKQ FT AEYEMDVIIQMGFPGYFLVVADFIMWAKNQGIAVGPGRGSAAGSIVAYAMGITDLDPIP FT HGLIFERFLNPERVSMPDVDIDFDERRRVEVIRYVTEKYGADKVAMIGTYGKIKAKNAI FT KDSARVLGYPYAMGDRLTKAMPADVLGKGIDLNGITDPTHPRYSEAGEIRSMYESEPDV FT KKVIDTAKGVEGLVRQMGVHAAGVIMSSEPIVDHAPIWVRHTDGVTITQWDYPQCESLG FT LLKMDFLGLRNLTIMDDAVKMVKSNKGIDLDLLSLPLDDPTTFELLQRGDTLGVFQFDG FT GPMRSLLRLMKPDNFEDISAVSALYRPGPMGMDSHTNYALRKNGLQEITPIHKELEEPL FT QEVLAVTYGLIVYQEQVQKAAQIIAGYSLGEADILRRVMGKKKPDELAKNFVLFQAGAR FT KNGYSDEAIQALWDVLVPFAGYAFNKAHSAAYGLVSYWTGYLKANYPAEYMAALLTSVK FT DDKDKSAVYLNECRRMGIKVLPPNVNESMSNFAAQGDDVILFGLSAVRNVGTNVVESII FT KCRKAKGKYASFPDYLDKVEAVVCNKRTTESLIKAGAFDEMGHTRKGLTAQYEPMIDNV FT VAVKRKEAEGQFDLFGGMGDEQSDEPGFGLDVVFGEDEWDKTYLLAQEREMLGLYVSDH FT PLFGLEHVLSDKADAGISQLTGGDFGDGAVVTIGGIISGLQRKMTKQGNAWAIATVEDL FT AGSLECMFFPATYQLVSTQLVEDAVVFVKGRLDKREDVPRLVAMELMIPDLSNAGTNAP FT VVLTIPATRITPPMVSRLGEILTHHRGDSEVRIKLQGPTKTTVLRLDRHRVKPDPALFG FT DLKVLLGPSCLAG" FT CDS 113379..114719 FT /transl_table=11 FT /gene="SCO2065" FT /gene_synonym="SC4G6.34" FT /product="conserved hypothetical protein" FT /note="SC4G6.34, unknown, len: 446 aa; weakly similar to FT two other hypothetical proteins from Streptomyces FT coelicolor; TR:CAB45208 (EMBL:AL079308) (509 aa) fasta FT scores; opt: 382, z-score: 443.7, E(): 2.2e-17, (33.3% FT identity in 448 aa overlap) and TR:O86499 (EMBL:AL031232) FT (469 aa) fasta scores; opt: 222, z-score: 259.2, E(): FT 4.1e-07, (27.7% identity in 437 aa overlap)" FT /db_xref="InterPro:IPR018721" FT /db_xref="UniProtKB/TrEMBL:Q9S2S5" FT /protein_id="CAB51457.1" FT /translation="MSVPQLNEEHRGEEILAVFDTAFGQLLAADPAAFRVKFRKMAASA FT FAFYRGTAGLFYRDLTEDPDFGDQHGGAYLDERTSRVWIHGDLHAENFGTYMDSTGRLI FT FNVNDFDEAYVGPFTWDLKRFAASVALIGYAKAFSDEQITELVRVYAGAYRERIHALAT FT GAKSDEVPPFTLDTAEGPLLGALRVARSLTRFGLLDSMTEIRDFERRFAPGGGSIELDA FT ATRYKVLAAFDGYLETLPESSLARPDSYRVKDVVGRRGIGIGSAGLPSYNILLEGNSDA FT LENDVVIYIKQAQTPAVSRHITDQAIRDYFRHEGHRTVISQRALQAHADPWLGWTELDG FT AGQLVAEVSPYAVDLDWGDIDDPEEIAEVVADLGRATATMHAAADDQSGESLVPFSTER FT AIDAAIAADEEGFAPLLVDFAHRYGARARADHQTFVDLFRNGRIPGL" FT CDS 114806..115516 FT /transl_table=11 FT /gene="SCO2066" FT /gene_synonym="SC4G6.35" FT /product="putative membrane protein" FT /note="SC4G6.35, possible membrane protein, len: 236aa; FT Contains possible membrane spanning hydrophobic regions." FT /db_xref="UniProtKB/TrEMBL:Q9S2S4" FT /protein_id="CAB51458.1" FT /translation="MDISGTPLRAVRAALFTALAVTLSTASHVLLSGVPLPLPTVAAVA FT AAVFLIAYALAGRRERGFGRIAALLIPLELAADTVFTTGQHVCYGRAGGPVAGPLRSVG FT FDVLCGDGTGVHAGVTAPLTRVTGAETDRMASVLAQADPGTAWLLLAAHVGVGLLAAAW FT LRRGERALAQLLGAVAATTFRPLLLAVAAVGVRRAPAVRRPTPPARRTTGARERILTHS FT LGRRGPPCPVATLV" FT CDS 115614..116414 FT /transl_table=11 FT /gene="SCO2067" FT /gene_synonym="SC4G6.36" FT /product="putative membrane protein" FT /note="SC4G6.36, putative membrane protein, len: 266 aa; FT weakly similar to TR:O69463 (EMBL:AL023635) hypothetical FT protein from Mycobacterium leprae (258 aa) fasta scores; FT opt: 250, z-score: 277.4, E(): 4e-08, (27.2% identity in FT 250 aa overlap) and similar to TR:Q9S2U7 (EMBL:AL096884) FT Streptomyces coelicolor putative integral membrane protein FT SC4G6.04c, 275 aa; fasta scores: opt: 519 Z-score: 568.5 FT E(): 4.9e-24; 34.470% identity in 264 aa overlap. Contains FT possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9S2S3" FT /protein_id="CAB51459.1" FT /translation="MSKRNSQAAKTAARERLRQERERQAKRDKVRRQVIVAASIVGVLA FT IAGGISYAVVQGNKPSGWDKAAEAKVVAPANTSGKDGTTVVIGESKSDHVIHLYEDPRC FT PGCAAMEQSIGETVNKGMEDGDYKLSFTVGTFLDGNLGGEGSKNALSALGAALNVSPEA FT FVDYKTALYSTKYHPEESTDEFAKDDYLIKVADSVDALKGNKKFQDAVEKGTYDAWAMR FT MSKSFDKAEGVESTPTIKINDKVVETPSTPDAWQKALKDAGVTK" FT CDS 116545..118200 FT /transl_table=11 FT /gene="SCO2068" FT /gene_synonym="SC4A10.01" FT /gene_synonym="SC4G6.37" FT /product="putative secreted alkaline phosphatase" FT /note="SC4A10.01, hypothetical protein, partial CDS, len: FT >67 aa; unknown function, probable CDS suggested by GC FT frameplot and positional base preference. Continues in FT cosmid 4G6 as SC4G6.39" FT /note="SC4G6.37, possible secreted alkaline phosphatase, FT len: >517aa; similar to SW:PPBD_BACSU alkaline phosphatase FT D from Bacillus subtilis (556 aa) fasta scores; opt: 837, FT z-score: 915.3, E(): 0, (34.3% identity in 539 aa overlap). FT Contains possible N-terminal region signal sequence FT peptide" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q8CK08" FT /protein_id="CAD55291.1" FT /translation="MTSRHRASENSRTPSRRTVVKAAAAGAVLAAPLAAALPAGAADAA FT PAFLHGVASGDPLPDGILLWTRVTPTPEAIPGSGTGPDTAVSWVVATDKDLTNVVAKGS FT VTATAAADHTVKADVRGLAPATDYWFRFSAGPTDSPVARTRTAPAHDAAVTGLRFGVVS FT CANWEAGYFSSYRHLAARGDLDAWLHLGDYIYEYGTGEYANRDTVVRPHAPAHEILTLA FT DYRIRHGRYKTDPDLQALHATAPVVAIWDDHEIANDTWSGGAENHTEGAEGTWAERQSA FT AKRAYFEWMPVRPAIAGTTYRRLRFGKLVDLSLLDLRTFRSQQVALGDGEVDDPDRTLT FT GRAQLDWLKSGLASSDATWRLVGNPVMISPFAVGSLPASLLGPLAELLGLPKEGIALNT FT DQWDGYTDDRRDLLAHLRAHAIRNTVFLTGDIHMAWANDVPYNAGTYPLSASAATEFVV FT TSVTSDNLDDIVKVPEGTVSAIAAPVIRAANRHVRWVDTDRHGYGVLDITADRAQMDYY FT VVSDRTDPRATSEWTRSYRTRSGTQRVERVYSPA" FT misc_feature 117996..118096 FT /note="Overlap with Streptomyces coelicolor cosmid 4A10." FT misc_feature 117996..118097 FT /note="overlap with Streptomyces coelicolor cosmid 4G6" FT CDS complement(118185..118775) FT /transl_table=11 FT /gene="SCO2069" FT /gene_synonym="SC4A10.02c" FT /product="conserved hypothetical protein" FT /note="SC4A10.02c, hypothetical protein, len: 196 aa; FT similar to the plasmid borne TR:CAC48425 (EMBL:AL603642) FT Rhizobium meliloti (Sinorhizobium meliloti) conserved FT hypothetical protein SMB20022, 188 aa; fasta scores: opt: FT 485 Z-score: 576.0 E(): 1.9e-24; 45.198% identity in 177 aa FT overlap. Probable CDS suggested by GC frameplot, positional FT base preference and amino acid composition. Annotated in FT cosmid 4G6 as SC4G6.38c" FT /db_xref="GOA:Q9R2D3" FT /db_xref="InterPro:IPR002925" FT /db_xref="UniProtKB/TrEMBL:Q9R2D3" FT /protein_id="CAB51978.1" FT /translation="MNIVLFHSTLGPRPAVRQAADRLRDAGHQVWTPDLFEGRTFDTVE FT EGMAHQDGIGREELLKRAVLAAAPYSERGLVYAGFSLGASIAQTLALGDHRARGLLLLH FT GTSDLAPNASVDELPVQLHVAEPDPFETDDWLSAWYLQMGRIGADVEVHRYPGAGHLYT FT DPGLDDYDAEAAEATWRVALGFLESLQEAQAGE" FT CDS 118881..120029 FT /transl_table=11 FT /gene="SCO2070" FT /gene_synonym="SC4A10.03" FT /product="putative membrane protein" FT /note="SC4A10.03, possible membrane protein, len: 382 aa; FT unknown function, shows weak similarity to parts of many FT hypothetical proteins e.g. SW:YB43_METJA (EMBL:U67556) FT Methanococcus jannaschii hypothetical protein (361 aa), FT fasta scores; opt: 222 z-score: 255.3 E(): 6.7e-07, 24.8% FT identity in 306 aa overlap. Contains hydrophobic, possible FT membrane-spanning regions. Contains Pfam match to entry FT PF00924 UPF0003, Uncharacterized protein family UPF0003" FT /db_xref="GOA:Q9S2Y1" FT /db_xref="InterPro:IPR006685" FT /db_xref="UniProtKB/TrEMBL:Q9S2Y1" FT /protein_id="CAB51979.1" FT /translation="METILRPLIVVGGSVLLTVVIGWATDLLLRKADGRHPETPLWGLL FT RRARVPYQIVLCSGLLRGSYVEAGVFPEHRTGVGRTLTLLLIGSVAWLVVRIAAAVVET FT SYSRYAHAHAERDPARVRRVRTQVSLIMRVVTAVVGVVAVSSMLLTFPAMRAAGASLLA FT SAGIIGIVAGVAAQSTLGNLFAGFQIAFGDMVRMGDTVVVDGEWGTVEEITLTYLSVRT FT WDERRITMPVSYFTSKPFENWSRGTPQMTGTVFWHLDHSAPMDLMRERLRDILRECPAW FT DGRNYNLTVTDTTPTTMEVRALVTAKDADDIWTVRVTVREGMLRWLADEHPYALPRVNT FT ADAALRPPRAGLPHARHAPDPAAGRSSDGDARRFPGRPAKSL" FT misc_feature 119130..119876 FT /note="Pfam match to entry PF00924 UPF0003, Uncharacterized FT protein family UPF0003, score 15.70, E-value 9.1e-09" FT CDS complement(120051..121637) FT /transl_table=11 FT /gene="SCO2071" FT /gene_synonym="SC4A10.04c" FT /product="putative Na+/H+ antiporter" FT /note="SC4A10.04c, possible Na+/H+ antiporter, len: 528 aa; FT shows weak similarity to the N-terminal portion of FT eukaryotic Na+/H+ antiporters e.g. SW:NAH3_RAT FT (EMBL:M85300) Rattus norvegicus sodium/hydrogen exchanger 3 FT (831 aa), fasta scores; opt: 271 z-score: 293.1 E(): FT 5.3e-09, 25.8% identity in 481 aa overlap. Similar to many FT putative Na+/H+ antiporters e.g. SW:YU23_MYCTU FT (EMBL:Z77163) Mycobacterium tuberculosis putative FT Na(+)/H(+) exchanger (542 aa) (31.4% identity in 528 aa FT overlap). Shows weak similarity to SC66T3.14c FT (EMBL:AL079348) S.coelicolor probable Na(+)/H(+) antiporter FT (514 aa) (27.5% identity in 545 aa overlap). Contains FT hydrophobic, possible membrane-spanning regions. Contains FT Pfam match to entry PF00999 Na_H_Exchanger, Sodium/hydrogen FT exchanger family" FT /db_xref="GOA:Q9S2Y0" FT /db_xref="InterPro:IPR018422" FT /db_xref="UniProtKB/TrEMBL:Q9S2Y0" FT /protein_id="CAB51980.1" FT /translation="MDQLALLFMLLLGALLSVPIGARLGLPAPVLMTLLGIVLALLDFV FT PNVDIPPELILPGLLPPLLYAAVRRTSWRQFAANKRPIFLLAVALVFVTMVCVASVAHA FT IVPGLPIAAAFALGALVAPPDPVAATAVAGQLGLPRRLVSILEGEGLFNDVTAIVLYHV FT AIAAAVGGSFSPWRAGFDLVLSAVVAVAIGLVLGWGSNKLMSVLGDPTLQIGLTLLVPF FT VSYVAADELHGSGVLAVLTTAMFLAEYASDADDVMTRLGGHTVWDVVDTLVTGVAFGLI FT GLELHNAVRTASGRWTELLGWAAAILVVVVLVRLLWLLPATWLTQRLHARRDQDEDIPT FT SWRETVVMWWAGMRGVASVALALAIPLETDDGAAFPHREEIVFIAFGVIMGTLLLQGLT FT LPWLVGRLGVRADTEREQEFERDLALRAAKAAKQRLKEIESVEELPEELSEQMLRRAFD FT IGIRISPDLGDEERREAQEQRARRIKRVRRIQGEMLSAARHEVLAARSEPGADPEIVDR FT VLRHLDVRSLR" FT misc_feature complement(120405..121628) FT /note="Pfam match to entry PF00999 Na_H_Exchanger, FT Sodium/hydrogen exchanger family, score 258.90, E-value FT 6.7e-74" FT CDS complement(121726..122208) FT /transl_table=11 FT /gene="SCO2072" FT /gene_synonym="SC4A10.05c" FT /product="hypothetical protein" FT /note="SC4A10.05c, hypothetical protein, len: 160 aa; FT unknown function, shows weak similarity to hypothetical FT proteins from other eubacteria e.g. SW:YYBD_BACSU FT (EMBL:D26185) Bacillus subtilis hypothetical protein (147 FT aa), fasta scores; opt: 199 z-score: 236.4 E(): 7.6e-06, FT 36.8% identity in 144 aa overlap. Shows weak similarity to FT SC5F7.12c (EMBL:AL096872) S.coelicolor possible FT acetyltransferase (169 aa) (37.7% identity in 114 aa FT overlap). Contains Pfam match to entry PF00583 FT Acetyltransf, Acetyltransferase (GNAT) family" FT /db_xref="GOA:Q9S2X9" FT /db_xref="HSSP:1Q2Y" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9S2X9" FT /protein_id="CAB51981.1" FT /translation="MPSRAPAAYEVRVAEDPVDREACFAVRKDVFVAEQKVPEDIEYDA FT YDADAVHVLAVREDGVPLGTGRLLHGAAAAAKNGDGDPAVGSLGRLAVTAAARGLGVGA FT ALVRAVEEAARARGLTAVDLHAQTHALGFYERLGYEAYGPEFPDAGIPHRAMRRAL" FT misc_feature complement(121789..122178) FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 60.20, E-value FT 4.6e-14" FT CDS complement(122211..123155) FT /transl_table=11 FT /gene="SCO2073" FT /gene_synonym="SC4A10.06c" FT /product="putative ribosomal large subunit pseudouridine FT synthase" FT /note="SC4A10.06c, possible ribosomal large subunit FT pseudouridine synthase, len: 314 aa; similar to many e.g. FT SW:RLUC_ECOLI (EMBL:AE000209), RluC, Escherichia coli FT ribosomal large subunit pseudouridine synthase C, fasta FT scores; opt: 415 z-score: 467.2 E(): 1.1e-18, 30.1% FT identity in 326 aa overlap and SW:RLUD_ECOLI (EMBL:U50134), FT RluD, Escherichia coli ribosomal large subunit FT pseudouridine synthase D (326 aa) (37.1% identity in 315 aa FT overlap). Highly similar to hypothetical proteins from FT mycobacteria e.g. MLCB458.15 (EMBL:AL049478), RluC, FT Mycobacterium leprae possible pseudouridine synthase (308 FT aa) (64.3% identity in 305 aa overlap). Contains Pfam FT matches to entry PF01479 S4, S4 domain and to entry PF00849 FT YABO, Hypothetical yabO/yceC/sfhB family" FT /db_xref="GOA:Q9S2X8" FT /db_xref="HSSP:1PRZ" FT /db_xref="InterPro:IPR006225" FT /db_xref="UniProtKB/TrEMBL:Q9S2X8" FT /protein_id="CAB51982.1" FT /translation="MSTIPEIRTLPVPDGLEGERVDAAISRMFGFSRTKAAELAAAGKV FT QVDGSVVGKSERVHGGAWLEVEMPQAPAPVQVVAEPVEGMEIVHDDEDVVVVVKPVGVA FT AHPSPGWSGPTVIGGLAAAGYRVSTSGAAERQGIVHRLDVGTSGLMAVAKSERAYTSLK FT RQFKERTVDKRYHTLVQGHPDPTSGTIDAPIGRHPQHDYKWAVTAEGKPSVTHYDLIEA FT FRAASLLDVKLETGRTHQIRVHMAAHRHPCVGDLTYGADPTLAKRLRLTRQWLHAVRLG FT FEHPGTGDWVEYASEYPDDLQQALDLVREETYG" FT misc_feature complement(122406..122894) FT /note="Pfam match to entry PF00849 YABO, Hypothetical FT yabO/yceC/sfhB family, score 234.80, E-value 1.2e-66" FT misc_feature complement(122919..123101) FT /note="Pfam match to entry PF01479 S4, S4 domain, score FT 22.20, E-value 0.0019" FT CDS complement(123281..123895) FT /transl_table=11 FT /gene="SCO2074" FT /gene_synonym="SC4A10.07c" FT /product="putative signal peptidase" FT /note="SC4A10.07c, probable signal peptidase, len: 204 aa; FT similar to many e.g. SW:LSPA_PSEFL (EMBL:M35366), LspA, FT Pseudomonas fluorescens lipoprotein signal peptidase (170 FT aa), fasta scores; opt: 250 z-score: 309.9 E(): 6.2e-10, FT 36.4% identity in 165 aa overlap, but contains an approx. FT 40 aa N-terminal extension not present in similar FT sequences. Contains Pfam match to entry PF01252 FT Peptidase_A8, Signal peptidase (SPase) II and possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9S2X7" FT /db_xref="InterPro:IPR001872" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2X7" FT /protein_id="CAB51983.1" FT /translation="MAEAERIIGTPDIPDAAGEGQERPDADPEREQQEQEQAPERTRGK FT RRVAVLFAVALFAYLLDLGSKMLVVAKLEHHEPIEIIGDWLRFAAIRNAGAAFGFGEAF FT TIIFTVIAAAVIVVIARLARKLHSLPWAIALGLLLGGALGNLTDRIFRAPGVFEGAVVD FT FIAPKHFAVFNLADSAIVCGGILIVILSFRGLDPDGTVHKD" FT misc_feature complement(123296..123751) FT /note="Pfam match to entry PF01252 Peptidase_A8, Signal FT peptidase (SPase) II, score 111.50, E-value 1.7e-29" FT CDS complement(123964..124683) FT /transl_table=11 FT /gene="SCO2075" FT /gene_synonym="SC4A10.08c" FT /product="putative DNA-binding protein" FT /note="SC4A10.08c, probable DNA-binding protein, len: 239 FT aa; the N-terminus is Lys- and Ala-rich, containing 13 FT degenerate AAKK(S)(P/T) repeats and is similar to FT histone-like proteins e.g. SW:KARP_CHLTR (EMBL:M86605), FT KarP, Chlamydia trachomatis developmentally regulated gene FT (207 aa), fasta scores; opt: 245 z-score: 253.5 E(): FT 8.5e-07, 44.7% identity in 114 aa overlap. This region is FT also similar to a repeat in TR:O86537 (EMBL:AL031124) FT S.coelicolor histone-like DNA binding protein (218 aa) FT (51.4% identity in 72 aa overlap). The C-terminus is FT similar to SW:DKSA_ECOLI (EMBL:M34945), DskA, Escherichia FT coli DnaK suppressor protein (151 aa) (28.8% identity in FT 125 aa overlap), a dosage-dependent suppressor of dnaK FT deletion mutants. Contains probable coiled-coil from 123 to FT 159 (37 residues) (Max score: 1.709, probability 1.00). FT Contains Pfam match to entry PF01258 zf_dskA_traR, FT Prokaryotic dksA/traR C4-type zinc finger and PS01102 FT Prokaryotic dksA/traR C4-type zinc finger" FT /db_xref="GOA:Q9S2X6" FT /db_xref="InterPro:IPR020460" FT /db_xref="UniProtKB/TrEMBL:Q9S2X6" FT /protein_id="CAB51984.1" FT /translation="MVAKKKTTAAKQSAAEESAAEQDPARKKAAEKTAAKKSPARKTAA FT KKSPAEKTAAKKSTAKKSTAKKVGAAEAAEQTGATTVVAKKTPGTATAAKTAVPKARGT FT AAVPGDLAVRPGEEPWTPQEVEEARGELQSEADRLRTEIDTSERSLQGMMRDSGDGAGD FT DEADTGSKNITREHELALAATAREVLSQTERALDRLDAGTYGLCENCGNPIGKARMQAF FT PRATLCVECKQKQERRY" FT misc_feature complement(123967..124167) FT /note="Pfam match to entry PF01258 zf_dskA_traR, FT Prokaryotic dksA/traR C4-type zinc finger, score 59.70, FT E-value 6.2e-14" FT misc_feature complement(123991..124065) FT /note="PS01102 Prokaryotic dksA/traR C4-type zinc finger" FT repeat_region complement(124483..124677) FT /note="13x approx. 15 bp degenerate direct repeats" FT CDS 125237..128380 FT /transl_table=11 FT /gene="SCO2076" FT /gene_synonym="SC4A10.09" FT /product="putative isoleucyl-tRNA synthetase" FT /note="SC4A10.09, probable isoleucyl-tRNA synthetase, len: FT 1047 aa; similar to many e.g. SW:SYIP_STAAU (EMBL:X75439), FT mupR, Staphylococcus aureus isoleucyl-tRNA synthetase FT conferring mupirocin resistance (1024 aa), fasta scores; FT opt: 2453 z-score: 2768.9 E(): 0, 38.2% identity in 985 aa FT overlap and SW:SYI_THETH, ileS, Thermus aquaticus FT isoleucyl-tRNA synthetase (821 aa) (49.1% identity in 831 FT aa overlap). Contains Pfam match to entry PF00133 FT tRNA-synt_1, tRNA synthetases class I (I, L, M and V)" FT /db_xref="GOA:Q9S2X5" FT /db_xref="HSSP:1ILE" FT /db_xref="InterPro:IPR013155" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2X5" FT /protein_id="CAB51985.1" FT /translation="MTTPQYRQVPAQVDLPALEHAVLDFWREQKIFAKSLEQSEGRPEW FT VFYEGPPTANGMPGAHHIEARVFKDVFPRFRTMRGYHVGRKAGWDCHGLPVELAVEKEL FT GFSGKQDIEAYGIAEFNAKCRESVTRHTDAFEELTTRMGYWADLQDPYRTMDPEYIESV FT WWSLKEIFNKGLLVQDHRVAPWCPRCGTGLSDHELAQGYETVVDPSVYVRFPLTSGPLA FT GEAALVVWTTTPWTLVSNTAVAAHPDVTYVVATDGEEKLVVAEPLLAKALGEGWETTGQ FT SFTGAEMERWTYQRPFELVEFPEPAHYVVNADYVTTEDGTGLVHQSPAFGEDDLKVCRA FT YGLPVVNPVRPDGTFEEDVPLVGGVFFKKADEKLTEDLETRGLLFKHIPYEHSYPHCWR FT CHTALLYYAQPSWYIRTTAIKDRLLQENEKTNWFPDAVKHGRYGDWLNNNIDWALSRNR FT YWGTPLPIWRCAEDHLTVVGSRAELTELSGTDQSSLDPHRPFIDDVTFTCAQEGCSLEA FT VRVPEVIDAWYDSGSMPFAQWGYPYKNKELFESRYPAQFISEAIDQTRGWFYTLMAVGT FT LVFDKSSYENVVCLGHILAEDGRKMSKHLGNILQPIPLMDQHGADAVRWFMAAGGSPWA FT ARRVGHGTIQEVVRKTLLTYWNTVAFQALYARTTGWAPSEADPAPADRPVLDRWLLSEL FT HALTDQVTQALDAYDTQRAGKLLSAFVDDLSNWYVRRSRRRFWQGDKAALRTLHEVVET FT VTKLMAPLTPFITERVWQDLVVPVTPGAPESVHLSSWPEADLTAIDPELSKQMVLVRRL FT VELGRATRAESGVKTRQPLSRALIAVAGFDTLSPELHSQITEELNVASLASLSEVGGSL FT VDTTAKANFRALGKRFGKRVQDVAKAVAAADAAALSLALREGTASVEVDGETVTLAPDE FT VIITETPREGWSVASDSGATVALDLELTEELRRAGLARDAIRLIQEARKNSGLDVADRI FT ALRWTATDPATIAALTDHSGLISDEVLATDFAQGEADDSYGAPFTDEGLSLVFRLRKQ" FT misc_feature 125297..127342 FT /note="Pfam match to entry PF00133 tRNA-synt_1, tRNA FT synthetases class I (I, L, M and V), score 723.00, E-value FT 1.3e-213" FT stem_loop 128512..128549 FT /note="stem, 17/17 (100%) matches, 0 gaps; loop, 4 bp" FT CDS complement(128582..129778) FT /transl_table=11 FT /gene="SCO2077" FT /gene_synonym="SC4A10.10c" FT /product="hypothetical protein" FT /note="SC4A10.10c, hypothetical protein, len: 398 aa; FT unknown function, probable Gln-, Met- and Pro-rich CDS FT suggested by GC frame plot, positional base preference and FT amino acid composition. Contains probable coiled-coils from FT 23 to 68 (46 residues) (Max score: 1.868, probability 1.00) FT and from 217 to 294 (78 residues) (Max score: 1.445, FT probability 0.86)" FT /db_xref="InterPro:IPR019933" FT /db_xref="UniProtKB/TrEMBL:Q9S2X4" FT /protein_id="CAB51986.1" FT /translation="MPLTPEDVRNKQFTTVRLREGYDEDEVDAFLDEVEAELTRLLREN FT EDLRAKLAAATRAAAQNQQNMRKPPEPPQDQQHQQGPPQHQQGPPQQGGMPQQGMRGPG FT APVPAGISGPPQQQMGGPMGGPPQLPSGAPQLPAGPGGQGGPQGPGPMGQGPGPMGQGP FT GPMQGQMGPGPMGGPMGGPQGPGGPGGPGMPGQGGPGGDSAARVLSLAQQTADQAIAEA FT RSEANKIVGEARSRAEGLERDARAKADALERDAQEKHRVAMGSLESARATLERKVEDLR FT GFEREYRTRLKSYLESQLRQLETQADDSLAPPRTPATASLPPSPAPSMAPAGASAPSYG FT GNQSMGGGPGQSGPSYGGQQQMSPAMTQPMAPVRPQGPSPMGQAPSPMRGFLIDEDDN" FT CDS complement(129834..130118) FT /transl_table=11 FT /gene="SCO2078" FT /gene_synonym="SC4A10.11c" FT /product="putative membrane protein" FT /note="SC4A10.11c, putative membrane protein, len: 94 aa; FT unknown function, similar to hypothetical proteins e.g. FT TR:O06230 (EMBL:Z95388) Mycobacterium tuberculosis FT hypothetical protein (96 aa), fasta scores; opt: 262 FT z-score: 367.1 E(): 4e-13, 41.9% identity in 86 aa overlap. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9S2X3" FT /db_xref="InterPro:IPR003425" FT /db_xref="UniProtKB/TrEMBL:Q9S2X3" FT /protein_id="CAB51987.1" FT /translation="MSVVLDVVYIALMCFLIVLIFRLVMDYVFQFARSWQPGKAMVVVL FT EATYTVTDPPLKLLRRFIPPLRLGGVALDLSFFVLMIIVYILISIVSQL" FT CDS complement(130200..130841) FT /transl_table=11 FT /gene="SCO2079" FT /gene_synonym="SC4A10.12c" FT /product="conserved hypothetical protein" FT /note="SC4A10.12c, conserved hypothetical protein, len: 213 FT aa; unknown function, similar to hypothetical proteins e.g. FT TR:O06229 (EMBL:Z95388) Mycobacterium tuberculosis FT hypothetical protein (241 aa), fasta scores; opt: 441 FT z-score: 479.6 E(): 2.2e-19, 40.8% identity in 218 aa FT overlap. The N-terminus is Asp- and Glu-rich" FT /db_xref="GOA:Q9S2X2" FT /db_xref="InterPro:IPR007561" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2X2" FT /protein_id="CAB51988.1" FT /translation="MAGAMRKMAVYLGLVEDDGYDGRGFDPDDDFEPELDPEPERDHRR FT HEPAHQSHGAHQSQRDEEVRVVQPPAQREPMPRAASLAAESSRPARIAPVASITQERAS FT LEKSAPVIMPKVVSEREPYRITTLHPRTYNEARTIGEHFREGTPVIMNLTEMDDTDAKR FT LVDFAAGLVFGLHGSIERVTQKVFLLSPANVDVTAEDKARIAEGGFFNQS" FT CDS complement(130970..131689) FT /transl_table=11 FT /gene="SCO2080" FT /gene_synonym="SC4A10.13c" FT /product="conserved hypothetical protein" FT /note="SC4A10.13c, conserved hypothetical protein, len: 239 FT aa; unknown function, similar to many hypothetical proteins FT e.g. SW:YPT5_PSEAE (EMBL:M55524) Pseudomonas aeruginosa FT hypothetical protein (230 aa), fasta scores; opt: 464 FT z-score: 546.4 E(): 4.1e-23, 39.7% identity in 229 aa FT overlap. Contains Pfam match to entry PF01168 UPF0001, FT Uncharacterized protein family UPF0001 and PS01211 FT Uncharacterized protein family UPF0001 signature" FT /db_xref="HSSP:1B54" FT /db_xref="InterPro:IPR011078" FT /db_xref="UniProtKB/TrEMBL:Q9S2X1" FT /protein_id="CAB51989.1" FT /translation="MTDRKHELAANLAKVEQRITDACAAAGRPRQDVTLIVVTKTYPAD FT DVRILSELGVRHVAENRDQDAAPKAAACSDLPLSWHFVGQLQTNKVRSVVGYADVVQSV FT DRARLVTALSKEAVRAGREVGCLLQVALDAEEGGRGERGGVPPAGIEELADLVAGSEGL FT RLDGLMTVAPLSGEYAGRQQAAFEHLMDLSTRVRRTHPAANMVSAGMSADLEQAVAAGA FT THVRVGTAVLGVRPRLG" FT misc_feature complement(130982..131662) FT /note="Pfam match to entry PF01168 UPF0001, Uncharacterized FT protein family UPF0001, score 155.50, E-value 9e-43" FT misc_feature complement(131408..131452) FT /note="PS01211 Uncharacterized protein family UPF0001 FT signature" FT CDS complement(131696..132424) FT /transl_table=11 FT /gene="SCO2081" FT /gene_synonym="SC4A10.14c" FT /product="conserved hypothetical protein" FT /note="SC4A10.14c, conserved hypothetical protein, len: 242 FT aa; unknown function, similar to many hypothetical proteins FT e.g. SW:YFIH_STRGR (EMBL:U07344) Streptomyces griseus FT hypothetical protein (246 aa), fasta scores; opt: 1246 FT z-score: 1349.0 E(): 0 76.3% identity in 245 aa overlap and FT SW:YFIH_ECOLI (EMBL:U50134), YfiH, Escherichia coli FT hypothetical protein (243 aa) (38.5% identity in 247 aa FT overlap)" FT /db_xref="InterPro:IPR003730" FT /db_xref="UniProtKB/Swiss-Prot:P45497" FT /protein_id="CAB51990.1" FT /translation="MIGQRDTVNGAHFGFTDRWGGVSAVPYEELNLGGAVGDDPGAVTA FT NRELAAKSLGVDPARVVWMNQVHGADVAVVDAPWGDRPVPRVDAVVTAERGLALAVLTA FT DCVPVLLADPVSGVAAAAHAGRPGLVAGVVPAAVRAMAELGADPARIVARTGPAVCGRC FT YEVPEEMRAEVAAVEPAAYAETGWGTPALDVSAGVHAQLERLGVHDRAQSPVCTRESAD FT HFSYRRDRTTGRLAGYVWLD" FT misc_feature complement(132244..137943) FT /note="sequence equivalent to EMBL:U10879 from 1 to 5700" FT CDS complement(132421..133620) FT /transl_table=11 FT /gene="SCO2082" FT /gene_synonym="SC4A10.15c" FT /gene_synonym="ftsZ" FT /product="cell division protein" FT /note="SC4A10.15c, ftsZ, cell division protein, len: 399 FT aa; previously sequenced as SW:FTSZ_STRCO (EMBL:U10879), FT ftsZ, Streptomyces coelicolor cell division protein (399 FT aa) and identical that sequence. Contains PS01134 FtsZ FT protein signature 1 and PS01135 FtsZ protein signature 2" FT /db_xref="GOA:P45500" FT /db_xref="HSSP:1OFU" FT /db_xref="InterPro:IPR003008" FT /db_xref="UniProtKB/Swiss-Prot:P45500" FT /protein_id="CAB51991.1" FT /translation="MAAPQNYLAVIKVIGVGGGGVNAINRMIEVGLKGVEFIAINTDAQ FT ALLMSDADVKLDVGRELTRGLGAGANPAVGRKAAEDHREEIEEVLKGADMVFVTAGEGG FT GTGTGGAPVVANIARSLGALTIGVVTRPFTFEGRRRANQAEDGIAELREEVDTLIVIPN FT DRLLSISDRQVSVLDAFKSADQVLLSGVQGITDLITTPGLINLDFADVKSVMSEAGSAL FT MGIGSARGDDRAVAAAEMAISSPLLEASIDGARGVLLSISGGSDLGLFEINEAAQLVSE FT AAHPEANIIFGAVIDDALGDEVRVTVIAAGFDGGQPPSKRDNVLGSSSAKREEPTPARP FT SESRPSFGSLGSVKPKEEPEPAPVPEPVADLPVSPPPVPPSRTYSDSAAEELDVPDFLK FT " FT misc_feature complement(133276..133341) FT /note="PS01135 FtsZ protein signature 2" FT misc_feature complement(133396..133500) FT /note="PS01134 FtsZ protein signature 1" FT CDS complement(133909..134703) FT /transl_table=11 FT /gene="SCO2083" FT /gene_synonym="SC4A10.16c" FT /gene_synonym="ftsQ" FT /product="sporulation protein" FT /note="SC4A10.16c, ftsQ, sporulation protein, len: 264 aa; FT previously sequenced as SW:FTSQ_STRCO (EMBL:U10879), ftsQ, FT Streptomyces coelicolor protein required for efficient FT sporulation, but not growth and viability (264 aa) and FT identical that sequence. Contains a hydrophobic, possible FT membrane-spanning region" FT /db_xref="GOA:P45518" FT /db_xref="InterPro:IPR013685" FT /db_xref="UniProtKB/Swiss-Prot:P45518" FT /protein_id="CAB51992.1" FT /translation="MAGPTTAERGARQQESSGPPRVRRFRPPRLRTIIILAVALVLVAG FT GTVWVLYGSNWTRLERVSVSGTDVLTPAQVREAADVPVGDPLVSVDTEAVEARLRRKLP FT RIDEVDVERSWPHGIGLKVTERTPVLIVQKGRNFVEVDDEGVRFATVSKAPKDVPTLEL FT EPARSGSAAASLRRFDDDRLVREAVRVAGRLPDKVARDTRVVKVRSYDDISLELSGGRT FT VSWGSGEQGVRKARALTALMKATPDARHFDVSVATAPASSGS" FT CDS complement(134729..135823) FT /transl_table=11 FT /gene="SCO2084" FT /gene_synonym="SC4A10.17c" FT /gene_synonym="murG" FT /product="putative FT UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) FT pyrophosphoryl-undecaprenol N-acetylglucosamine FT transferase" FT /note="SC4A10.17c, murG, probable FT UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) FT pyrophosphoryl-undecaprenol N-acetylglucosamine FT transferase, len: 364 aa; previously sequenced as TR:Q9ZBA5 FT (EMBL:U10879), MurG, Streptomyces coelicolor FT UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) FT pyrophosphoryl-undecaprenol N-acetylglucosamine transferase FT (364 aa) and identical to that sequence. Similar to many FT e.g. TR:O07109 (EMBL:U94707), MurG, Enterococcus faecalis FT UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) FT pyrophosphoryl-undecaprenol N-acetylglucosamine transferase FT (363 aa), fasta scores; opt: 648 z-score: 711.4 E(): FT 2.8e-32, 33.2% identity in 365 aa overlap" FT /db_xref="GOA:Q9ZBA5" FT /db_xref="HSSP:1F0K" FT /db_xref="InterPro:IPR007235" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZBA5" FT /protein_id="CAB51993.1" FT /translation="MHVVLAGGGTAGHIEPALALADALRRQDPTVGITALGTERGLETR FT LVPERGYELALIPAVPLPRKPTPELITVPGRLRGTIKATEQILERTKADAVAGFGGYVA FT LPAYLAAKRLGVPIVVHEANARPGLANKIGSRYAAQVAVSTPDSKLRNSRYIGIPLRRS FT IATLDRAAARPEARAMFGLDPNLPTLLVTGGSQGARRLNEVIQQVAPWLQQAGIQILHA FT VGPKNELPQVHQMPGMPPYIPVSYLDRMDLAYAAADMMLCRAGAMTVAELSAVGLPAAY FT VPLPIGNGEQRLNAQPVVKAGGGLLVDDAELTPEWLQQNVLPVLADPHRLYEMSRAAAE FT FGRRDADDLLVGMVYEAIAARARR" FT CDS complement(135830..137200) FT /transl_table=11 FT /gene="SCO2085" FT /gene_synonym="SC4A10.18c" FT /gene_synonym="ftsW" FT /product="putative cell division protein" FT /note="SC4A10.18c, ftsW, probable cell division protein, FT len; 456 aa; previously sequenced as TR:Q9ZBA6 FT (EMBL:U10879), ftsW, Streptomyces coelicolor ftsW protein FT (456 aa) and identical to that sequence. Similar to many FT members of the ftsW/rodA/spoVE family e.g. SW:SP5E_BACSU FT (EMBL:X51419), spoVE, Bacillus subtilis stage V sporulation FT protein (366 aa), fasta scores; opt: 745 z-score: 788.4 FT E(): 0, 36.9% identity in 350 aa overlap. Shows similarity FT to SC6G9.31 (EMBL:AL079356) S.coelicolor probable integral FT membrane cell-cycle protein (446 aa) (30.0% identity in 416 FT aa overlap) and SCH69.16 (EMBL:AL079308) S.coelicolor FT probable FtsW/RodA/SpoVE family cell cycle protein (479 aa) FT (28.6% identity in 385 aa overlap). Contains hydrophobic, FT possible membrane-spanning regions. Contains Pfam match to FT entry PF01098 FTSW_RODA_SPOVE, Cell cycle protein and FT PS00428 Cell cycle proteins ftsW/rodA/spoVE signature" FT /db_xref="GOA:Q9ZBA6" FT /db_xref="InterPro:IPR018365" FT /db_xref="UniProtKB/TrEMBL:Q9ZBA6" FT /protein_id="CAB51994.1" FT /translation="MPGSPQSRTGRPPVQRTVKRPAAPGPPHDNGVLRLYHRLRRAWDR FT PLTAYYLIFGGSALITVLGLVMVYSASQITALQLSLPGSYFFRKQALAALIGAGLLVAA FT MKMPVKLHRALAYPILAGAVFLMILVQVPGIGVAVNGNQNWISLGGSFQIQPSEFGKLA FT LVLWGADLLARKHDKKLLTQWKHMLVPLVPAAFMLLGLIMIGGDMGTAIILTAILFGLL FT WLAGAPTRLFAGVLSIALLLGFILIKTSANRMARLNCLGATDPGPGDSCWQAVHGIYAL FT ASGGLFGSGLGASVEKWGQLPEAHTDFIFAVTGEELGLAGTLSVLALFAALGYAGIRVA FT GRTEDPFVRYAAGGVTTWITAQAVINIGAVLGLLPIAGVPLPLFSYGGSALLPTMFAIG FT LLIAFARDEPGARAALALRQPRFGRKRGAGGPAAKRSPGSWNTMRRRASAARSSGER" FT misc_feature complement(135971..137053) FT /note="Pfam match to entry PF01098 FTSW_RODA_SPOVE, Cell FT cycle protein, score 340.10, E-value 2.5e-98" FT misc_feature complement(136031..136105) FT /note="PS00428 Cell cycle proteins ftsW / rodA / spoVE FT signature" FT CDS complement(137278..138693) FT /transl_table=11 FT /gene="SCO2086" FT /gene_synonym="SC4A10.19c" FT /gene_synonym="murD" FT /product="putative UDP-N-acetylmuramoylalanine-D-glutamate FT ligase" FT /note="SC4A10.19c, murD, FT UDP-N-acetylmuramoylalanine-D-glutamate ligase, len: 471 FT aa; previously partially sequenced as TR:Q9ZBA7 FT (EMBL:U10879), MurD, Streptomyces coelicolor FT UDP-N-acetylmuramoylalanine-D-glutamate ligase (fragment) FT (221 aa) and identical to that sequence. Similar to many FT e.g. TR:O68388 (EMBL:AF035938), MurD, Streptococcus FT pyogenes UDP-N-acetylmuramoylalanine-D-glutamate ligase FT (452 aa), fasta scores; opt: 399 z-score: 431.5 E(): FT 1.1e-16, 33.3% identity in 469 aa overlap. Shows weak FT similarity to SC9B1.07 (EMBL:AL049727) S.coelicolor FT possible UDP-N-acetylmuramyl-L-alanine ligase (462 aa) FT (27.9% identity in 480 aa overlap). Contains Pfam match to FT entry PF01225 Mur_ligase, Mur ligase family" FT /db_xref="GOA:Q9S2W9" FT /db_xref="HSSP:3UAG" FT /db_xref="InterPro:IPR005762" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2W9" FT /protein_id="CAB51995.1" FT /translation="MPSEFSGKHVTVAGLGVSGVPAAKVLHGLGAQVTVVNDGDDERAR FT TQAAELEPLGVTVRLGDGDTLPEGTELIVTAPGWKPTKPLFTAAGQAGVPVWGDVELAW FT RLRGLNGRKPAPWLAVTGTNGKTTTVQMLASILKAAGLRTAAVGNIGVSLLDAVTGEQE FT YDVLAVELSSYQLHWAPSLRAHSAAVLNLAPDHLDWHGSMEAYAADKGRIYEGNHVACV FT YNVADKATEDLVRAADVEEGCRAIGFTLGTPGPSQLGVVEGLLVDRAFVEDRQKNAQEL FT AEVSDVNPPAPHNIANALAAAGLARAFGVSAAAVRDGLRAFTPDAHRIAHVADVDGVAY FT VDDSKATNTHATEASLAAYESIVWIAGGLAKGATFDELVAGAAKRLRGAVLIGADRALI FT REALARHAPEVPVVDLDRTDTGAMLQAVQEARRLARPGDTVLLAPACASMDMFTNYNQR FT GDAFAQAVRELGA" FT misc_feature complement(137650..138345) FT /note="Pfam match to entry PF01225 Mur_ligase, Mur ligase FT family, score 167.50, E-value 2.2e-46" FT CDS complement(138702..139793) FT /transl_table=11 FT /gene="SCO2087" FT /gene_synonym="murX" FT /gene_synonym="SC4A10.20c" FT /product="putative FT phospho-N-acetylmuramoyl-pentapeptide-transferase" FT /note="SC4A10.20c, murX, probable FT phospho-N-acetylmuramoyl-pentapeptide-transferase, len: 363 FT aa; similar to many e.g. SW:MRAY_ECOLI (EMBL:X51584), MraY, FT MurX, Escherichia coli FT phospho-N-acetylmuramoyl-pentapeptide-transferase involved FT in peptidoglycan biosynthesis (360 aa), fasta scores; opt: FT 615 z-score: 714.6 E(): 1.8e-32, 43.3% identity in 344 aa FT overlap. Also similar to TR:O69555 (EMBL:AL022602), MurX, FT Mycobacterium leprae probable FT phospho-N-acetylmuramoyl-pentapeptide-transferase (359 aa) FT (51.8% identity in 361 aa overlap). Contains hydrophobic, FT possible membrane-spanning regions. Contains Pfam match to FT entry PF00953 Glycos_transf_4, Glycosyl transferase" FT /db_xref="GOA:P56833" FT /db_xref="InterPro:IPR018480" FT /db_xref="UniProtKB/Swiss-Prot:P56833" FT /protein_id="CAB51996.1" FT /translation="MKQILFAGVIGLFLTLVGTPLLIKLLARKGYGQYIRDDGPREHAS FT KRGTPTMGGIAFILATVAAYFLAKGITSYLDPDIDAGPTFSGLLVLGLMVGMGLVGFLD FT DYIKIVKRRSLGLRARAKMIGQLTVGIAFAVLSLQFADNRGNTPASTKLSFITDFGWTI FT GPVLFVVWALFMILAMSNGVNLTDGLDGLATGASVLVFGAYTFIGVWQFQESCANALTL FT TNPGACYEVRDPLDLAVVASALMGSCLGFLWWNTSPAKIFMGDTGSLALGGVLAGLAIC FT SRTELLMAILGGLFVLITMSVVIQVGSFRLTGKRVFRMAPLQHHFELKGWSEVLVVVRF FT WIIQGICVIVGLGLFYAGWATDK" FT misc_feature complement(138930..139535) FT /note="Pfam match to entry PF00953 Glycos_transf_4, FT Glycosyl transferase, score 197.20, E-value 2.5e-55" FT CDS complement(139793..141208) FT /transl_table=11 FT /gene="SCO2088" FT /gene_synonym="SC4A10.21c" FT /gene_synonym="murF" FT /product="putative FT UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-alanyl FT ligase" FT /note="SC4A10.21c, murF, probable FT UDP-N-acetylmuramoylalanyl-D-glutamyl- 2,6-diaminopimelate- FT D-alanyl-alanyl ligase, len: 471 aa; similar to many e.g. FT SW:MURF_ECOLI (EMBL:X15432), Mra, MurF, Escherichia coli FT UDP-N-acetylmuramoylalanyl-D-glutamyl- 2,6-diaminopimelate- FT D-alanyl-alanyl ligase (452 aa), fasta scores; opt: 774 FT z-score: 866.3 E(): 0, 36.1% identity in 471 aa overlap. FT Also similar to SW:MURF_STRTO (EMBL:U82965), MurF, MurX, FT Streptomyces toyocaensis probable FT UDP-N-acetylmuramoylalanyl-D-glutamyl- 2,6-diaminopimelate- FT D-alanyl-alanyl ligase (443 aa) (50.4% identity in 464 aa FT overlap). Shows weak similarity to others from S.coelicolor FT e.g. SC9B1.07 (EMBL:AL049727) S.coelicolor possible FT UDP-N-acetylmuramoyl-L-alanine ligase (462 aa) (24.1% FT identity in 464 aa overlap). Contains Pfam match to entry FT PF01225 Mur_ligase, Mur ligase family" FT /db_xref="GOA:Q9S2W8" FT /db_xref="HSSP:1GG4" FT /db_xref="InterPro:IPR013221" FT /db_xref="UniProtKB/TrEMBL:Q9S2W8" FT /protein_id="CAB51997.1" FT /translation="MITLSLAEIAEVVGGRMHDIPDASAEVTGPVVRDSREAGPGSLFV FT AFVGERADGHDFAARVVEAGAVAVLGSRPVGVPAIVVDDVQAALGALARHVVRRLGTTL FT VALTGSAGKTSTKDLIAQVLRRKAPTVFTPGSMNNEVGLPLTALTATDETKFLVLEMGA FT RGIGHIRYLTELTPPKIGAVLNVGSAHIGEFGGREQIAQAKGELVEALPPAEEGGAAIL FT NADDPLVRAMASRTKAKVILFGESGEADVRAENVRLTDTGQPSFSLHTPSGASDVTMRL FT YGEHHVSNALAAAAVAHELGMSADEIATALSEAGSLSRWRMEVTERPDGVTVVNDAYNA FT NPESTKAALRALVAMGKGRRTWAVLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGG FT REARWLQLGAYNEGSWGEESVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLESVATA FT LLETGAEGEVAAR" FT misc_feature complement(140183..140899) FT /note="Pfam match to entry PF01225 Mur_ligase, Mur ligase FT family, score 213.30, E-value 3.8e-60" FT CDS complement(141269..142789) FT /transl_table=11 FT /gene="SCO2089" FT /gene_synonym="SC4A10.22c" FT /gene_synonym="murE" FT /product="putative FT UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate FT ligase" FT /note="SC4A10.22c, murE, probable FT UDP-N-acetylmuramoylalanyl-D-glutamate- 2,6-diaminopimelate FT ligase, len: 506 aa; previously partially sequenced as FT TR:Q9Z5V6 (EMBL:AF123319), MurE, Streptomyces coelicolor FT UDP-N-acetylmuramoylalanyl-D-glutamate- 2,6-diaminopimelate FT ligase (fragment) (142 aa) and identical to that sequence. FT Similar to many e.g. SW:MURE_ECOLI (EMBL:X55814), MurE, FT Escherichia coli UDP-N-acetylmuramoylalanyl-D-glutamate- FT 2,6-diaminopimelate ligase (494 aa), fasta scores; opt: 889 FT z-score: 881.7 E(): 0, 37.9% identity in 486 aa overlap and FT SW:MURE_MYCTU (EMBL:Z95388), MurE, Mycobacterium FT tuberculosis probable FT UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelat e FT ligase (535 aa) (50.3% identity in 519 aa overlap). Shows FT weak similarity to others from S.coelicolor e.g. SC9B1.07 FT (EMBL:AL049727) S.coelicolor possible FT UDP-N-acetylmuramoyl-L-alanine ligase (462 aa) (26.6% FT identity in 497 aa overlap). Contains Pfam match to entry FT PF01225 Mur_ligase, Mur ligase family" FT /db_xref="GOA:Q9S2W7" FT /db_xref="HSSP:1E8C" FT /db_xref="InterPro:IPR013221" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2W7" FT /protein_id="CAB51998.1" FT /translation="MTYPGPPRPVRISATPLAELADQLGVAAPDGSAEITGITHDSRAV FT RPGDLYAALPGARLHGADFVTQAAGLGAAAVLTDPAGAERAAAAGLPALVVDDPRARMG FT ELAATIYGHPGRDLLQIGITGTSGKTTTAYLVEGGLRTAKSTGLIGTVEMRIGDERIKS FT ERTTPEATDLQALFAVMRERGTEAVAMEVSSHALVLGRVDACVFDIAVFTNLSPEHMEF FT HSGMEDYFQAKAQLFTPKRSRLGVVNVDDEYGRRLAKEATVPVVTYSAEGHPDADWRAD FT EVEVGPLDSTFTVLGPKGERIAAKSPLAGPFNVANTLAAIVALAAAGLDPQSAADGVAA FT VPGVPGRLERVDEGQPFFAVVDYAHKTDAVESVLRALRKVTEGKLHAVLGCGGDRDTTK FT REPMGAAVARFADTAVLTSDNPRSEDPLAILATMLQGAASVPAHERGEVQVFEDRAAAI FT AAAVARAEPGDTVLVAGKGHEQGQDIAGVVRPFDDRQVLREAIKKTQG" FT misc_feature complement(141689..142432) FT /note="Pfam match to entry PF01225 Mur_ligase, Mur ligase FT family, score 239.60, E-value 4.5e-68" FT misc_feature complement(142499..145449) FT /note="sequence equivalent to EMBL:AF123319 from 1 to 2951 FT AF123319" FT CDS complement(142997..144961) FT /transl_table=11 FT /gene="SCO2090" FT /gene_synonym="SC4A10.23c" FT /gene_synonym="ftsI" FT /product="cell division protein" FT /note="SC4A10.23c, ftsI, cell division protein, len: 654 FT aa; previously sequenced as TR:Q9Z5V7 (EMBL:AF123319), FT FtsI, Streptomyces coelicolor cell division protein (651 FT aa) and identical to that sequence, but with a different FT putative start codon. C-terminal end shares weak similarity FT with others from S.coelicolor e.g. SC6G9.32 (EMBL:AL079356) FT S.coelicolor possible penicillin-binding protein (485 aa) FT (29.3% identity in 447 aa overlap). Contains a hydrophobic, FT possible membrane-spanning region. Contains Pfam match to FT entry PF00905 Transpeptidase, Penicillin binding protein FT transpeptidase domain and two PS00017 ATP/GTP-binding site FT motif A (P-loop)" FT /db_xref="GOA:Q9S2W6" FT /db_xref="HSSP:1QME" FT /db_xref="InterPro:IPR001460" FT /db_xref="UniProtKB/TrEMBL:Q9S2W6" FT /protein_id="CAB51999.1" FT /translation="MTEVSDREPPRRRVPGPARPVRSGGGRRPGPGARPARRPGPPRPA FT PRAFRLGSPRPRLRMIGLALTLVLAAFVVRLLQVQAVDAGTYSAKAEQNRYVVHTLPAE FT RGGITDRNGVALATTVDSYDITAEPTMFTREQLKVDDGPEQAAALLAPILGQDQEQLAK FT VLRPKNRELRYVRLARRQTPQVWNQIKDLKTALTAKAETDRATVNVLAGVFADPSSKRV FT YPGGDLAAGILGWVGADGKGGGGLERKLDTTLAGEDGKIRYAQSGGRQVPTAGSTETPA FT VPGSDVELTIDRDIQWAAQHAISEQVEKSKADGGYVIVQDTTTGEILAMANSPGFDPGD FT LAHADPAALGNAALQDAFEPGSTAKVLSMAAVLEENVATPGTHITVPNRLKRGDRLFKD FT DIDHPTWYLTLNGVLAKSSNIGTIMATGELGKTQAEANKVLYSYLRKFGLGGYSGLGFP FT GETKGILAPPDQWSTSQQYTIPFGQGVSVNALQAASIYSTVANGGVRIEPTLVRGTKGA FT DGRFTPAPEPKKTRVTSEKTAKTLSQMLESVVDDEEGTGTKARIPGYRVAGKTGTANRV FT DPATGKYHGYTSSFAGFAPADKPRVTVYCAIQNATEGSYFGGQICGPIYKQVMEFALKT FT LQVPPTGAAPARLPVTFKP" FT misc_feature complement(143081..144085) FT /note="Pfam match to entry PF00905 Transpeptidase, FT Penicillin binding protein transpeptidase domain, score FT 311.30, E-value 1.1e-89" FT misc_feature complement(143252..143275) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(143666..143689) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(144958..145578) FT /transl_table=11 FT /gene="SCO2091" FT /gene_synonym="SC4A10.24c" FT /product="putative membrane protein" FT /note="SC4A10.24c, possible membrane protein, len: 206 aa; FT unknown function, previously partially sequenced as FT TR:Q9Z5V8 (EMBL:AF123319) Streptomyces coelicolor FT hypothetical protein (fragment) (163 aa) and identical to FT that sequence. Similar to a central region of mycobacterial FT hypothetical proteins e.g. TR:O06213 (EMBL:Z95388) FT Mycobacterium tuberculosis hypothetical protein (384 aa), FT fasta scores; opt: 282 z-score: 255.8 E(): 6.8e-07, 36.2% FT identity in 224 aa overlap. Contains a hydrophobic, FT possible membrane-spanning region and probable coiled-coil FT from 74 to 109 (36 residues) (Max score: 1.684, probability FT 1.00)" FT /db_xref="GOA:Q9S2W5" FT /db_xref="InterPro:IPR007060" FT /db_xref="UniProtKB/TrEMBL:Q9S2W5" FT /protein_id="CAB52000.1" FT /translation="MADPSGPRDPGKIQTTPPRGGRVSRKPELKGRAARLARLLPTGGS FT RGQAARAPFVLLVVVLLGGGLIGLLVLNSALSEGSFQLDDLKQRTKELTDEEQALQRDI FT DAYSAPRALQRRARELGMVPGGDPAFLDPDGTVKGVPSPAPAAATPLVLAPEALASTSA FT GASTVTPSPYSEPSGPPPTAAPSGTAATPTTAAPPTPTPTPGR" FT RBS complement(145588..145592) FT /note="possible RBS" FT CDS complement(145685..146617) FT /transl_table=11 FT /gene="SCO2092" FT /gene_synonym="SC4A10.25c" FT /product="conserved hypothetical protein" FT /note="SC4A10.25c, conserved hypothetical protein, len: 310 FT aa; unknown function, similar to many hypothetical proteins FT e.g. TR:O06212 (EMBL:Z95388) Mycobacterium tuberculosis FT hypothetical protein (396 aa), fasta scores; opt: 1037 FT z-score: 1165.6 E(): 0, 53.7% identity in 313 aa overlap, FT which is longer at the N-terminus. The majority of possible FT homologues are 300-320 aa in length" FT /db_xref="GOA:Q9S2W4" FT /db_xref="HSSP:1M6Y" FT /db_xref="InterPro:IPR002903" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2W4" FT /protein_id="CAB52001.1" FT /translation="MMLQRCLDLLAPALQEPGAVVVDCTLGLGGHSEALLERFPEARLV FT ALDRDKEALRLSGERLAPYGGRATLVHAVYDELPDVLDRLGVPRVQGVLFDLGVSSMQL FT DEADRGFAYAQDAPLDMRMDQSTGMSAAEVLNTYPPGELVRILRAYGEEKQAKRIVSAV FT VREREKEPFTNSARLVELIRAALPQAAKRTGGNPAKRTFQALRIEVNGELSVLERAIPA FT AVESVAVGGRIAVLSYHSLEDRLVKQVFAAGAANTAPPGLPVVPEQYAPRLKLLTRGAE FT LPTEEEIAENRRAAPARLRGAERIRESLG" FT CDS 147114..147617 FT /transl_table=11 FT /gene="SCO2093" FT /gene_synonym="SC4A10.26" FT /product="conserved hypothetical protein" FT /note="SC4A10.26, conserved hypothetical protein, len: 167 FT aa; unknown function, similar to other hypothetical FT proteins e.g. SW:Y023_MYCTU (EMBL:Z73419) Mycobacterium FT tuberculosis hypothetical protein (163 aa), fasta scores; FT opt: 567 z-score: 691.9 E(): 3.2e-31, 53.4% identity in 163 FT aa overlap. Very weak similarity to the C-terminus of many FT carbonic anhydrases e.g. TR:P93109 (EMBL:U80805) FT Chlamydomonas reinhardtii beta-carbonic anhydrase (267 aa) FT (24.3% identity in 181 aa overlap)" FT /db_xref="GOA:Q9S2W3" FT /db_xref="HSSP:1G5C" FT /db_xref="InterPro:IPR001765" FT /db_xref="UniProtKB/TrEMBL:Q9S2W3" FT /protein_id="CAB52002.1" FT /translation="MADHTVTDRLVEANERYAAAFADPGMDARPVQRVAVVACMDARLD FT LHAALGLKLGDCHTIRNAGGVVTDDVIRSLTISQRALGTRSVALIHHTGCGMETITEEF FT RHDLELEVGQRPAWAVEAFRDADQDVRQSIERVRTSPFLLHTEDVRGFVFDVKTGLLRE FT VDPA" FT CDS 147934..148947 FT /transl_table=11 FT /gene="SCO2094" FT /gene_synonym="SC4A10.27" FT /product="putative regulatory protein" FT /note="SC4A10.27, possible regulatory protein, len: 337 aa; FT similar to many e.g. SW:MOXR_PARDE (EMBL:M57684), MoxR, FT Paracoccus denitrificans protein probably involved in the FT regulation of methanol dehydrogenase synthesis (339 aa), FT fasta scores; opt: 189 z-score:216.0 E(): 7.6e-05, 31.55% FT identity in 336 aa overlap. Similar to many hypothetical FT proteins e.g. TM1132 (EMBL:AE001771) Thermotoga maritima FT putative MoxR protein (305 aa) (52.1% identity in 303 aa FT overlap). Similar to TR:Q9Z538 (EMBL:AL035212) S.coelicolor FT possible regulatory protein (332 aa) (45.8% identity in 312 FT aa overlap)" FT /db_xref="GOA:Q9S2W2" FT /db_xref="InterPro:IPR016366" FT /db_xref="UniProtKB/TrEMBL:Q9S2W2" FT /protein_id="CAB52003.1" FT /translation="MGEDLTAVVERVRGSVEDVIEGKPEVVRLSLTVLLAEGHLLIEDV FT PGVGKTMLAKALARSIDCSVRRIQFTPDLLPSDITGVSIWDQQRRDFEFKPGAIFAQVV FT IGDEINRASPKTQSALLESMEERQVTIDGQTYELPSPFMVVATQNPVEMEGTYPLPEAQ FT RDRFMARVSIGYPSPEAELQMLDVHGGASPLDDLQPVAHAHDILKLIEAVRGVHVADPV FT RRYAVDLVAATRTHPDLRLGASPRATLHLLRAAKASAALSGRDYALPDDVQALAVAVLA FT HRLLPTAQAQLNRRTAEQVVQEILQRTAVPAEPQQQTGFGVGRGTPAYGQQPPRRV" FT CDS 148944..150308 FT /transl_table=11 FT /gene="SCO2095" FT /gene_synonym="SC4A10.28" FT /product="putative membrane protein" FT /note="SC4A10.28, possible membrane protein, len: 454 aa; FT unknown function, similar to parts of bacterial FT hypothetical proteins e.g. TR:P74479 (EMBL:D90915) FT Synechocystis sp hypothetical protein (406 aa), fasta FT scores; opt: 266 z-score: 307.9 E(): 8e-10, 30.4% identity FT in 253 aa overlap. Contains hydrophobic, possible FT membrane-spanning regions near the N-terminus" FT /db_xref="InterPro:IPR002881" FT /db_xref="UniProtKB/TrEMBL:Q9S2W1" FT /protein_id="CAB52004.1" FT /translation="MMDAGGTDRSAADGGEGGGIRTALSGLTTRGRSFLAAGIAAAVCA FT YVLGQSDLLRVGLLLGALPLVCAAVLHRTRYRVAGSRRLSPGRVPAGSEARVHLRVDNV FT SRLPTGLLMLQDRVPYVLGPRPRFVLDRVEPGGRREVSYRVRSDLRGRFPLGPLQLRLT FT DPFGLCELTRSFSTYDTLTVIPRVAALPPVRLSGEAKGYGEGRQRSLALAGDDDVIPRG FT YRYGDDLRRVHWRSTARYGELMVRREEQPQRARCTVLLDTRVVAFEGAGPDSAFEWAVS FT GAASVLVHMLERGFSVRLLTGNGDAVPGEGADGFAGASQGTADAAGLMMDTLAVIDHSD FT DTSLSRAYDMLRGGNEGLLVAFFGDLDEEQATVVAKMRQRGGGAVAFVLDSETWAREPA FT DVPGPPAGSDERLRMLREAGWTAVAVPRGATVEEVWRMADHERTTLAAPAGGEGA" FT CDS 150305..152698 FT /transl_table=11 FT /gene="SCO2096" FT /gene_synonym="SC4A10.29" FT /product="putative membrane protein" FT /note="SC4A10.29, possible membrane protein, len: 797 aa; FT unknown function, shows weak similarity to parts of other FT bacterial hypothetical proteins e.g. TR:P94476 FT (EMBL:U51115), yebA, Bacillus subtilis hypothetical protein FT (655 aa), fasta scores; opt: 335 z-score: 330.0 E(): FT 4.7e-11, 30.4% identity in 263 aa overlap. Contains FT hydrophobic, possible membrane-spanning regions in the FT N-terminus" FT /db_xref="InterPro:IPR002931" FT /db_xref="UniProtKB/TrEMBL:Q9S2W0" FT /protein_id="CAB52005.1" FT /translation="MMSGRARLAMCAWAATLMAACALLPLVEPATWILQAAVLLAVQSG FT VGAVARRVPLARPLTIAAQALVTLVLLTLVFARQQALAGLVPDPQAFQRFADLLQQGGD FT DIARYAIPAPLESDGIRLMLVGGVLVIGLLVDTLAVTFRSAAPAGLPLLALYSVAAGLS FT EGGADWLWFLVAAVGYLMLLLAEGRDRLSQWGRVFGGSARPPGPEQGRALAPVRTGRRI FT GAFALGIALVVPLALPAMDGGLLDGAGGGVGSGTGGGGTISAVNPLVSLRDSLNVNEDR FT QVLSVQTDSEDLSDLYLRIVSLDDFDGTTWKPSKRRITAVPDGTFPTPAGLGPDVRRTE FT TRALISAADWYAQDWLPMPYPPSGVRVAGNWRFEPVGMTLVGDHGQNTRGLKYEVRSLN FT VQPTAEQLAAAPPPSAALTREYTELPDSLPDVVFRTAREVTAGAANPYEQAVKLQEYFA FT VNGGFEYDTQVKVGSGSEAIARFLKDKEGFCVHFSFAMAAMARSLGIPARVAVGFAPGS FT PQADGSVSVGLRDAHAWPEVYFEGVGWTRFEPTPTRGSTPSYTITDRPGSSVPDPAVPS FT QSAEAEPSAAPSSSDTCAPQDKKLDACPNESAVAVPVTGDDGPKWYALPAWALAGLLVL FT LLPLAPMLWRLRARAVRLGAHGRGAADVGPHTLAVWQELTDAAWDLGILPQESQTPRKA FT AARIVRLGGLEPTAAQAVHRVADAVEQVLYAPHPRPAAGLAEDVRLATAGLRAGVGRGT FT RLRARFAPRSAIRVTWTVSARWTALKRRAAAARPQWRRTSDQQG" FT stem_loop 152774..152818 FT /note="stem, 20/20 (100%) matches, 0 gaps; loop, 5 bp" FT CDS complement(152850..153257) FT /transl_table=11 FT /gene="SCO2097" FT /gene_synonym="SC4A10.30c" FT /product="putative membrane protein" FT /note="SC4A10.30c, possible membrane protein, len: 135 aa; FT unknown function, similar to mycobacterial hypothetical FT proteins TR:O53503 (EMBL:AL021957) Mycobacterium FT tuberculosis (134 aa), fasta scores; opt: 349 z-score: FT 414.6 E(): 9e-16, 44.1% identity in 136 aa overlap and its FT homologue in Mycobacterium leprae TR:O69562 (EMBL:AL022602) FT Mycobacterium leprae hypothetical protein (134 aa) (42.6% FT identity in 136 aa overlap). Contains hydrophobic, possible FT membrane-spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9S2V9" FT /protein_id="CAB52006.1" FT /translation="MPLSEHEQRMLEQMERALYAEDPKFATALEGSGLRTYTRRRVYQA FT VAGFLVGIALLMAGMVAQQVWLSVVGFLVMLGCAVLAVTGWRKAPKPGEQQQAAGAGPQ FT AARRQGRQKRSMMDRIDERWQRRRDEQQGGQ" FT RBS complement(153263..153268) FT /note="possible RBS" FT CDS complement(153534..154349) FT /transl_table=11 FT /gene="SCO2098" FT /gene_synonym="SC4A10.31c" FT /product="putative methyltransferase" FT /note="SC4A10.31c, possible methyltransferase, len: 271 aa; FT shows weak similarity to SW:SMTA_ECOLI (EMBL:D26440), SmtA, FT Escherichia coli S-adenosylmethionine-dependent FT methyltransferase (261 aa), fasta scores; opt: 311 z-score: FT 330.3 E(): 4.5e-11, 32.0% identity in 250 aa overlap and to FT SC5F7.31 (EMBL:AL096872) S.coelicolor possible FT methyltransferase (233 aa) (34.3% identity in 236 aa FT overlap)" FT /db_xref="GOA:Q9S2V8" FT /db_xref="InterPro:IPR013217" FT /db_xref="UniProtKB/TrEMBL:Q9S2V8" FT /protein_id="CAB52007.1" FT /translation="MRPPASHPRPHTAVSRSEPSRSRAALRTAVVWDVLQDALDRRVKA FT TGRPTLDVLDTGGGSGNFAVPVAGLGHRVTVVDPSPNALFALERRAAEAGVADRVRGVQ FT GDARGLFDVAERGGYDAVLCHGVLEYVDDPAEGVRNAVAALREDGVLSLLAAGLGGAVL FT ARALAGHFTEARQALADPDGRWGTGDPVPRRFTAEQLTGLVEAAGLRIGAVHGVRVFAD FT LVPGVLVDTEPGAMDALLKLEAAAAELAAFHSVATQLHVLGETRGAGEA" FT CDS 154540..155046 FT /transl_table=11 FT /gene="SCO2099" FT /gene_synonym="SC4A10.32" FT /product="hypothetical protein" FT /note="SC4A10.32, hypothetical protein, len: 168 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition" FT /db_xref="UniProtKB/TrEMBL:Q9S2V7" FT /protein_id="CAB52008.1" FT /translation="MTGVGTAGPLGALARWVRVGAGLGQDRLEDQHPLHQAQEHRHVAY FT QVVGVPAARRAPDARLGARPARRAGGEQRAPLGQLGRDLGQHLPGAADAGPGPWAGLRA FT AARGQHRGGGAQGGEVGRRVALVRRFEGGGLLQPGPGLGEQVEGGGRGGRPAEHGVHVA FT RRSGQ" FT CDS 155287..155916 FT /transl_table=11 FT /gene="SCO2100" FT /gene_synonym="SC4A10.33" FT /product="putative transcriptional regulator" FT /note="SC4A10.33, probable transcriptional regulator, len: FT 209 aa; shows weak similarity to many hypothetical proteins FT e.g. TR:O53641 (EMBL:AL021927) Mycobacterium tuberculosis FT hypothetical protein (214 aa), fasta scores; opt: 224 FT z-score: 282.1 E(): 2.2e-08, 28.8% identity in 208 aa FT overlap and to SCI30A.20c (EMBL:AL096811) S.coelicolor FT possible transcriptional regulator (215 aa) (31.6% identity FT in 190 aa overlap). Contains probable helix-turn-helix FT motif at aa 38-59 (Score 1454, +4.14 SD) and Pfam match to FT entry PF00440 tetR, Bacterial regulatory proteins, tetR FT family" FT /db_xref="GOA:Q9S2V6" FT /db_xref="InterPro:IPR015893" FT /db_xref="UniProtKB/TrEMBL:Q9S2V6" FT /protein_id="CAB52009.1" FT /translation="MESSSTASQSGSRREATRQKLYEAAVTLIAEQGFSATTVDEIAER FT AGVAKGTVYYNFASKSVLFEELLRHGVGLLTASLRQAAERTAREGRGRVDALDAMIRAG FT LVFIDRYPAFTQLYVAELWRTNRAWQSTLLVVRQEAVAVVEGVLREGVASGEFSEDIDV FT PLTAAALVGMVLVAALDWKAFQPERSLDDVHAALSRLLQGRVSGRG" FT misc_feature 155347..155487 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 58.00, E-value FT 2.4e-14" FT CDS 156402..157922 FT /transl_table=11 FT /gene="SCO2101" FT /gene_synonym="SC4A10.34" FT /product="putative carotenoid dehydrogenase (putative FT secreted protein)" FT /note="SC4A10.34, probable carotenoid dehydrogenase FT (putative secreted protein), len: 506 aa; similar to many FT bacterial and fungal carotenoid dehydrogenases e.g. FT SW:CRTD_RHOSH (EMBL:X63204) CrtD, Rhodobacter sphaeroides FT methoxyneurosporene dehydrogenase (495 aa), fasta scores; FT opt: 470 z-score: 505.2 E(): 8.1e-21, 29.2% identity in 506 FT aa overlap. Shows very weak similarity to TR:Q9ZBG4 FT (EMBL:AL035206) S. coelicolor possible dehydrogenase (472 FT aa) (28.1% identity in 523 aa overlap). Contains possible FT N-terminal region signal peptide sequence" FT /db_xref="GOA:Q9S2V5" FT /db_xref="InterPro:IPR006076" FT /db_xref="UniProtKB/TrEMBL:Q9S2V5" FT /protein_id="CAB52010.1" FT /translation="MARIAVIGAGMGAMAAAARLAVAGHRVVVYERAGTYGGALGRVER FT DGFRFDTGPGLLPLPAVWRDLFVKTGKEPLESRVELVQVDPSSRHVFADGTEVALPNAS FT RAGVVAALDAVLGAGAGRRWGDFLVRARETWDRTRRPLLEEPLWPNWRVLAEREPYPAV FT PHKRLLRTRRAGTLAEVGAWELRDARLAALLESHALAHGLDPRTAPANAAVLPYMEYAF FT GVWYVRGGGLRELARAVYERCLARRVEFRFGAEVTGIVEKDGRVAGVELAEGTVAEAEF FT VVSGVAPGVLDRLCGGAPVRGGGEVPPQRGGASRLTVLLALRGSRPAGTAHRTVVHAAD FT RETELDRLFGAAPGMAARPTVTVLRPDDPALVPDADHEAVTLSAAVPALDGASDRATTE FT VFAHWAGQLMEVAERAVPGLRDRLLWHEVRTPAEVAADTGAADGAIPVPSLAGADGRLL FT HPANGTRTDGLFTVGGWSHPGGGLPHAGMSGALVAGLVVEGPEFRGSQ" FT CDS complement(157944..158936) FT /transl_table=11 FT /gene="SCO2102" FT /gene_synonym="SC4A10.35c" FT /product="putative membrane protein" FT /note="SC4A10.35c, possible membrane protein, len: 330 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. The FT C-terminal half is Gln-rich. Contains hydrophobic, possible FT membrane-spanning regions in the N-terminus" FT /db_xref="UniProtKB/TrEMBL:Q9S2V4" FT /protein_id="CAB52011.1" FT /translation="MGWTVLYIAFGVVALWLLGEVLLQYKARLRWRLLAFAGFVGVVAG FT VLMSNVLVIGVGAAAFAVGQTYVTLSFRRGFEAGWAVNAPASLVGKRGRPERGRREPTL FT EVSGLEPAEGGPDHHDGYDEPAPGQDGTGSYGHDDYDRDDVFTPARPTADPSAAETTAV FT YEPQPMPDDTNSYGVYTDAGYGTGQQQAAAAPDADQAYAYDYSGYGQQQEYGYDTGAQQ FT QYAAYSDPYIGTHTYGGGTYDTGGYDTTGEQNYGQQGYGQDQYAPGAPGAPGAPGGYGG FT ETPAGGVWVPQQRSTDDPYGGELPPEQQPYPYQGDGQTQGQGYDEQYRF" FT CDS complement(158993..159916) FT /transl_table=11 FT /gene="SCO2103" FT /gene_synonym="SC4A10.36c" FT /gene_synonym="metF" FT /product="5,10-methylenetetrahydrofolate reductase" FT /note="SC4A10.36c, metF, 5,10-methylenetetrahydrofolate FT reductase, len: 307 aa; identical to SW:METF_STRLI FT (EMBL:AJ001630), MetF, Streptomyces lividans FT 5,10-methylenetetrahydrofolate reductase (307 aa), apart FT from substitution of Arg41 for Lys41 in S.coelicolor, fasta FT scores; opt: 2015 z-score: 2364.3 E(): 0, 99.7% identity in FT 307 aa overlap" FT /db_xref="GOA:Q9S2V3" FT /db_xref="HSSP:1B5T" FT /db_xref="InterPro:IPR004620" FT /db_xref="UniProtKB/TrEMBL:Q9S2V3" FT /protein_id="CAB52012.1" FT /translation="MALGTASTRTDRARTVRDILATGKTTYSFEFSAPKTPKGERNLWS FT ALRRVEAVAPDFVSVTYGAGGSTRAGTVRETQQIVADTTLTPVAHLTAVDHSVAELRNI FT IGQYADAGIRNMLAVRGDPPGDPNADWIAHPEGLTYAAELVRLIKESGDFCVGVAAFPE FT MHPRSADWDTDVTNFVDKCRAGADYAITQMFFQPDSYLRLRDRVAAAGCATPVIPEVMP FT VTSVKMLERLPKLSNASFPAELKERILTAKDDPAAVRSIGIEFATEFCARLLAEGVPGL FT HFITLNNSTATLEIYENLGLHHPPRA" FT CDS complement(160055..160726) FT /transl_table=11 FT /gene="SCO2104" FT /gene_synonym="SC4A10.37c" FT /product="putative thiamin phosphate pyrophosphorylase" FT /note="SC4A10.37c, possible thiamin phosphate FT pyrophosphorylase, len: 223 aa; similar to TR:O34294 FT (EMBL:AF004408), thiE, from Rhizobium etli plasmid pb (204 FT aa), fasta scores; opt: 251 z-score: 300.4 E(): 2.1e-09, FT 35.5% identity in 183 aa overlap. Also similar to many FT hypothetical thiamin phosphate pyrophosphorylases e.g. FT SW:THIE_MYCTU (EMBL:Z84724), thiE, Mycobacterium FT tuberculosis probable thiamin-phosphate pyrophosphorylase FT (63.0% identity in 219 aa overlap)" FT /db_xref="GOA:Q9S2V2" FT /db_xref="HSSP:1G4E" FT /db_xref="InterPro:IPR003733" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2V2" FT /protein_id="CAB52013.1" FT /translation="MPDTAPTAARARLADARLYLCTDARRSQGDLPEFLDAVLAGGVDI FT VQLRDKGMEAAEELEHLAVFADACARHGKLLAVNDRADVAHAARADVLHLGQGDLPVPA FT ARAILGDDVLIGRSTHAESEAAAAAAQEGVDYFCTGPCWPTPTKPGRHAPGLDLVRRTA FT ALGTDRPWFAIGGIDLGNLDEVLEAGARRVVVVRAITAAEDPGAAAAEFARRLRQAPAH FT G" FT CDS complement(160881..161246) FT /transl_table=11 FT /gene="SCO2105" FT /gene_synonym="SC2C1A.01c" FT /gene_synonym="SC4A10.38c" FT /product="putative transcriptional regulatory protein" FT /note="SC2C1A.01c, possible transcriptional regulatory FT protein, partial CDS, len: > 57 aa. Similar to FT Mycobacterium tuberculosis TR:O53509 (EMBL:AL021957) FT hypothetical protein (146 aa), fasta scores opt: 137 FT z-score: 204.5 E(): 0.00048 42.3% identity in 71 aa FT overlap. Overlaps and extends into CDS SC4A10.38c on the FT adjoining cosmid. Contains a putative helix-turn-helix FT motif situated between residues 17..38 (+4.08 SD)." FT /note="SC4A10.38c, conserved hypothetical protein, partial FT CDS, len: >86 aa; similar to mycobacterial hypothetical FT proteins TR:O53509 (EMBL:AL021957) Mycobacterium FT tuberculosis hypothetical protein (146 aa), fasta scores; FT opt: 198 z-score: 273.9 E(): 6.2e-08, 43.9% identity in 98 FT aa overlap and TR:O69567 (EMBL:AL022602) Mycobacterium FT leprae possible transcriptional regulator (134 aa) (44.8% FT identity in 96 aa overlap)" FT /db_xref="UniProtKB/TrEMBL:Q8CK07" FT /protein_id="CAD55292.1" FT /translation="MTEIDAKTDALVPAWLTVPDIAEMLGVEVTRVRQLIKEGQLIAVR FT RGENRALHIPAAFIDEDKVVKGLVGTLTLLRDDGFTDEEMLEWLFTPDPSLPGTPAQAL FT SENRGTEVKRRAQALAV" FT misc_feature 161042..161142 FT /note="overlap with Streptomyces coelicolor cosmid 2C1A FT from 1 to 101" FT RBS complement(161248..161252) FT CDS complement(161288..162511) FT /transl_table=11 FT /gene="SCO2106" FT /gene_synonym="SC2C1A.02c" FT /product="putative oxidoreductase" FT /note="SC2C1A.02c, possible oxidoreductase, len: 407 aa. FT Highly similar to several reductases including: Rhodococcus FT sp. (strain NI86/21) SW:THCD_RHOSN(EMBL:U17130) rhodocoxin FT reductase (EC 1.18.1.-) (426 aa), fasta scores opt: 792 FT z-score: 833.9 E():0 36.9% identity in 412 aa overlap and FT Sphingomonas sp. TR:O65946(EMBL:AJ002606) reductase, RedA2, FT protein (409 aa), fasta scores opt:794 z-score: 836.2 E():0 FT 40.1% identity in 409 aa overlap" FT /db_xref="GOA:Q9RL65" FT /db_xref="HSSP:1D7Y" FT /db_xref="InterPro:IPR013027" FT /db_xref="UniProtKB/TrEMBL:Q9RL65" FT /protein_id="CAB61699.1" FT /translation="MVVVGAGMAGVQTAVALREQGFTGPVTLIGAEPHQPYDRPPLSKA FT VLLGTAEGSAFDVDFEALGITLRLGCEALGVRPAEHVLDTSEGPVPYDVLVLATGAEPV FT RLPGAEGVPGVHLLRTLDDAERLRPVLARQHDVVVVGAGWIGAEFATAAREAGCAVTVV FT EAADRPLADALPAEVAAPMTAWYADAGAELRTRARVERVESGGPGESGRVVLDDGTRLA FT AGAVVVGIGARPATGWLAGSGIALGAHGEVLADDLLRTSAPDVHAVGDCASFPSARYGE FT RLLVHHWDNALQGPRTVAADIVGTPGGETPAAYDPVPYFWSEQFGRFVQYAGHHTAADT FT TLWRGDPASPAWTVCWLREGRLVALLAVGRPRDLAQGRRLIQAGTPMDPDLLADPAKPL FT KAATAATA" FT RBS complement(162518..162521) FT RBS 162811..162815 FT CDS 162828..164033 FT /transl_table=11 FT /gene="SCO2107" FT /gene_synonym="SC6E10.01" FT /gene_synonym="SC2C1A.03" FT /product="putative oxidoreductase" FT /note="SC6E10.01, possible oxidoreductase, partial CDS, FT len: >375 aa; similar to TR:O85228 (EMBL:AF053760), HcnC, FT Pseudomonas fluorescens hydrogen cyanide synthase (417 aa), FT fasta scores; opt: 511 z-score: 564.8 E(): 3.9e-24, 30.7% FT identity in 348 aa overlap, although they are more FT divergent at the N-terminus. Also similar to many other FT oxidoreductases and hypothetical proteins" FT /note="SC2C1A.03, possible oxidoreductase, partial CDS, FT len: > 40 aa. Similar to Bacillus subtilis FT SW:DLD2_BACSU(EMBL:D84432) dihydrolipoamide dehydrogenase FT (EC 1.8.1.4) (474 aa), fasta scores opt: 111 z-score: 145.4 FT E(): 0.94 54.3% identity in 35 aa overlap. Overlaps and FT extends into CDS SC6E10.01 on the adjoining cosmid" FT /db_xref="GOA:Q8CK06" FT /db_xref="HSSP:1NG4" FT /db_xref="InterPro:IPR003042" FT /db_xref="UniProtKB/TrEMBL:Q8CK06" FT /protein_id="CAD55293.1" FT /translation="MSSPSHTPPHTPRTSRTPDVLVVGGGIIGLVTAWRAARRGLVTAL FT VDPEPGGGAAQVAAGMLAAVTELHYGEETLLALNLASARRYPEFAAELTELTGHDLGYR FT RCGTLAVALDADDRAHLRELHALQQRSGLESEWLSGRECRRLEPMLAPGVRGGLRVDGD FT HQIDPRRLARALVAACEHAGVVFHRVWAERLTVGRGDRATGVVGADGTALEAGQVVLAG FT GSLSGRLGGVPEAVLPPVRPVKGQVLRLTMPRTPGPLLNRTVRAVVRGNHVYLVPRESG FT ELVVGATSEELGWDTTVTAGGVYELLRDAHELVPGITELPLTETRAGLRPGSPDNAPLL FT GPTALDGLLLATGHYRNGVLLTPVTGDVMAEALTGGELPDVARPFGPRRFGAVPARSEQ FT PA" FT CDS 164030..164230 FT /transl_table=11 FT /gene="SCO2108" FT /gene_synonym="SC6E10.02" FT /product="hypothetical protein" FT /note="SC6E10.02, conserved hypothetical protein, len: 66 FT aa; unknown function, similar to e.g. SW:THIS_ECOLI FT (EMBL:M88701), ThiS, ThiG1, Escherichia coli hypothetical FT protein in thiamine biosynthetic operon (66 aa), fasta FT scores; opt: 138 z-score: 203.8 E(): 0.0005, 30.3% FT identity in 66 aa overlap and to TR:P96262 (EMBL:Z84724) FT Mycobacterium tuberculosis hypothetical protein (68 aa) FT (39.7% identity in 68 aa overlap)" FT /db_xref="GOA:Q9S2N5" FT /db_xref="InterPro:IPR010035" FT /db_xref="UniProtKB/TrEMBL:Q9S2N5" FT /protein_id="CAB51956.1" FT /translation="MNISVNGEPREVAPGTALDALVGTLTAAPSGVAAALNETVVPRAR FT WSATALADGDRVEILTAVQGG" FT CDS 164233..165027 FT /transl_table=11 FT /gene="SCO2109" FT /gene_synonym="SC6E10.03" FT /gene_synonym="thiG" FT /product="putative thiazole biosynthesis protein" FT /note="SC6E10.03, thiG, probable thiazole biosynthesis FT protein, len: 264 aa; similar to SW:THIG_ECOLI FT (EMBL:U00006), thiG, Escherichia coli thiamine biosynthetic FT enzyme (281 aa), fasta scores; opt: 750 z-score: 820.0 E(): FT 0, 49.2% identity in 244 aa overlap. Similar to many other FT thiG proteins. Highest similarity is to TR:P96263 FT (EMBL:Z84724) Mycobacterium tuberculosis hypothetical FT protein (252 aa), (71.7% identity in 251 aa overlap)" FT /db_xref="GOA:Q9S2N4" FT /db_xref="InterPro:IPR008867" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2N4" FT /protein_id="CAB51957.1" FT /translation="MADDPFVLGGTTYASRLIMGTGGAPSLDVLERALVASGTELTTVA FT MRRVNASVHGSVLSVLERLGIRVLPNTAGCFTAGEAVLTARLAREALGTDLVKLEVIAD FT ERTLLPDPVELLDAAETLVDDGFTVLPYTNDDPVLARKLEDAGCAAIMPLGSPIGSGLG FT IRNPHNFQLIVEHARVPVILDAGAGTASDVALAMELGCAGVMLASAVTRAQEPVLMAAA FT MRAGVEAGRLARRAGRIPRRHFAEASSPAEGLAVLDPERPAF" FT misc_feature 164720..167211 FT /note="sequence equivalent to Streptomyces coelicolor gene FT for eukaryotic-type protein kinase (EMBL:AB019394)" FT CDS 165186..167189 FT /transl_table=11 FT /gene="SCO2110" FT /gene_synonym="SC6E10.04" FT /gene_synonym="pkaF" FT /product="putative eukaryotic-type serine/threonine protein FT kinase" FT /note="SC6E10.04, pkaF, probable eukaryotic-type FT serine/threonine protein kinase, len: 667 aa; previously FT sequenced as TR:Q9ZNB3 (EMBL:AB019394) S.coelicolor FT eukaryotic-type protein kinase (629 aa) and identical to FT that sequence, but with a different putative start codon. FT Similar to many e.g. SW:PKN2_MYXXA (EMBL:M94857), Pkn2, FT Myxococcus xanthus serine/threonine protein kinase involved FT in regulation of beta-lactamase secretion (830 aa), fasta FT scores; opt: 564 z-score: 531.4 E(): 2.8e-22, 35.5% FT identity in 366 aa overlap. Similar to many hypothetical FT protein serine/threonine protein kinases from mycobacteria FT e.g. TR:O53510 (EMBL:AL021957) Mycobacterium tuberculosis FT (399 aa) (43.4% identity in 394 aa overlap). Similar to FT others from S.coelicolor e.g. SCH69.18 (EMBL:AL079308) FT S.coelicolor possible serine/threonine protein kinase (673 FT aa) (34.7% identity in 622 aa overlap). Alternative start FT codons are present at codons 3 and 11. Contains probable FT coiled-coil from 543 to 576 (34 residues) (Max score: FT 1.485, probability 0.93). Contains Pfam match to entry FT PF00069 pkinase, Eukaryotic protein kinase domain and FT PS00108 Serine/Threonine protein kinases active-site FT signature and possible hydrophobic membrane spanning FT region" FT /db_xref="GOA:Q9S2N3" FT /db_xref="HSSP:1MRU" FT /db_xref="InterPro:IPR008271" FT /db_xref="UniProtKB/TrEMBL:Q9S2N3" FT /protein_id="CAB51958.1" FT /translation="MSVAARTLTCVDTTLQDPLVGQVLDGRYRVEARIAVGGMATVYRA FT VDTRLDRVLALKVMHPTLATDATFVERFIREAKSVARLDHPNVVQVFDQGAEGAYVYLA FT MEYIAGCTLRDVLRERGALRPRAALDILEPVLAALGAAHRAGFVHRDMKPENVLIGDDG FT RVKVADFGLVRAVDTVTSTTGAVLGTVSYLAPEQIEHGTADPRVDVYACGVMLYEMLTG FT AKPHDGDSPAAVLYKHLHEDVPPPSAAVPELAYELDELVAAATARNPEIRPHDAVALLA FT RAREARESLSTAQLDAVPPQALAAEHDNAEDRTSVIPRALTMPRPLPVNEDDGSAGPDG FT RFASDGGFGADGVNRTSRLAAPPPAPSPSRRLRLRRGPLTIVVAVLLVLGIGTGVWYIN FT SGQFTKVPPLLSKTEAQARDRLDDAGLDVGKVRHAYSDTVERGKVISTDPGVGDRIRKN FT DSVSLTVSDGPDTVKLPDVTGYKLDKARTLLEDEGLEPGMVTRAFSDEVARGFVISTKP FT GSGTTVRAGSAVALVVSKGSPVDVPDVTGDDLDEARAELEGAGLKVKTADERVNSEYDS FT GRVARQTPEPGGRAAEGDTVTLTVSKGPRMIEVPDVVGDSVDDAKQKLEDAGFEVDEDR FT GLLGLFGDTVKKQSVDGGDTAPEGSTVTITIR" FT misc_feature 165267..165956 FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 177.50, E-value 2.2e-49" FT misc_feature 165624..165662 FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT CDS 167374..168258 FT /transl_table=11 FT /gene="SCO2111" FT /gene_synonym="SC6E10.05" FT /product="putative endonuclease" FT /note="SC6E10.05, probable endonuclease, len: 294 aa; FT similar to many DNA-repair endonucleases e.g. SW:END4_ECOLI FT (EMBL:M22591), nfo, Escherichia coli endonuclease IV (285 FT aa), fasta scores; opt: 482 z-score: 516.5 E(): 1.9e-21, FT 33.3% identity in 279 aa overlap and SW:APN1_YEAST FT (EMBL:M33667), apn1, Saccharomyces cerevisiae DNA-(apurinic FT or apyrimidinic site) lyase (366 aa) (28.4% identity in 289 FT aa overlap). Contains Pfam match to entry PF01261 FT AP_endonuclease2, AP endonuclease family 2, PS00730 AP FT endonucleases family 2 signature 2 and PS00731 AP FT endonucleases family 2 signature 3" FT /db_xref="GOA:Q9S2N2" FT /db_xref="HSSP:1QTW" FT /db_xref="InterPro:IPR013022" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2N2" FT /protein_id="CAB51959.1" FT /translation="MSTASSSSSLPRNPVGGHVPVAGGLHSVGLSYARELKAEAVQVFV FT ANPRGWATPAGNPKQDEAFREACAAGSVPAYVHAPYLINFGSHTGATVERSVESLRHSL FT RRGRAIGALGVVVHTGSATGGRERPVALKQVREHMLPLLDELTHDDDPYLLLESTAGQG FT ASLCSRTWDFGPYFEALDAHPKLGVCLDTCHIFAAGHDLTGPSGMHQTLDLLVDTVGEG FT RLRLIHANDSKDVAGAHKDRHENIGAGHIGEDPFRALMTHPATDGVPLVIETPGGKEGH FT AADVARLKKLRDG" FT misc_feature 167428..168252 FT /note="Pfam match to entry PF01261 AP_endonuclease2, AP FT endonuclease family 2, score 193.00, E-value 4.8e-54" FT misc_feature 167932..167955 FT /note="PS00730 AP endonucleases family 2 signature 2" FT misc_feature 168052..168096 FT /note="PS00731 AP endonucleases family 2 signature 3" FT CDS complement(168305..168952) FT /transl_table=11 FT /gene="SCO2112" FT /gene_synonym="SC6E10.06c" FT /product="conserved hypothetical protein" FT /note="SC6E10.06c, hypothetical protein, len: 215 aa; FT unknown function, similar to hypothetical proteins e.g. FT TR:O32103 (EMBL:Z99120) Bacillus subtilis hypothetical FT protein (198 aa), fasta scores; opt: 522 z-score: 625.8 FT E(): 1.5e-27, 40.6% identity in 192 aa overlap. Shares a FT short sequence motif from aa 150-160 with many FT oxidoreductases (sulfite oxidases and nitrate reductases). FT An alternative start codon is present at codon 5" FT /db_xref="GOA:Q9S2N1" FT /db_xref="InterPro:IPR000572" FT /db_xref="UniProtKB/TrEMBL:Q9S2N1" FT /protein_id="CAB51960.1" FT /translation="MGQPVEHGSGEDGSQGASWSELPPGQRLQRGWPVTHYGPVPKFRP FT ERWEFRVFGATTDDEKHGWTHDEFGALPYTTVVADLHCVTKFSMLGAEWGGVPATTILE FT LAPPAPAVTHVMVWAEYGFSSNLRLSDFAAERTLFATHKDGELLTAEHGFPVRLVVPHL FT YAWKGPKWVRGIEYMTADRRGFWEERGYHNIGDPWREQRYSYQEEPGDGPEP" FT RBS complement(168960..168963) FT /note="possible RBS" FT misc_feature 169144..169605 FT /note="Pfam match to entry PF01334 Bacteriofer, FT Bacterioferritin, score 282.10, E-value 7.2e-81" FT CDS 169144..169647 FT /transl_table=11 FT /gene="SCO2113" FT /gene_synonym="SC6E10.07" FT /gene_synonym="bfr" FT /product="putative bacterioferritin" FT /note="SC6E10.07, bfr, probable bacterioferritin, len: 167 FT aa; highly similar to SW:BFR_MYCAV (EMBL:X76906) Bfr, FT Mycobacterium avium bacterioferritin (159 aa), fasta FT scores; opt: 672 z-score: 815.6 E(): 0, 63.6% identity in FT 162 aa overlap. Contains Pfam match to entry PF01334 FT Bacteriofer, Bacterioferritin" FT /db_xref="GOA:Q9S2N0" FT /db_xref="HSSP:1BCF" FT /db_xref="InterPro:IPR012347" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2N0" FT /protein_id="CAB51961.1" FT /translation="MQGDPEVIEFLNEQLTAELTAINQYFLHAKLQDHKGWTKLAKYTR FT AESFDEMRHAEVLTDRILLLDGLPNYQRLFHVRVGQSVTEMFQADREVELEAIDRLRRG FT IEVMRAKHDITSANVFEAILADEEHHIDYLETQLDLIEKLGESLYLSTVIEQTQPDPSG FT PGSL" FT CDS complement(169664..169915) FT /transl_table=11 FT /gene="SCO2114" FT /gene_synonym="SC6E10.08c" FT /product="hypothetical protein" FT /note="SC6E10.08c, hypothetical protein, len: 83 aa; FT unknown function, similar to part of many nitrate or FT nitrite reductases e.g. SW:NIR_EMENI (EMBL:M58289), NiiA, FT Emericella nidulans nitrite reductase (1104 aa), fasta FT scores; opt: 137 z-score: 178.6 E(): 0.013, 38.0% identity FT in 50 aa overlap" FT /db_xref="InterPro:IPR007419" FT /db_xref="UniProtKB/TrEMBL:Q9S2M9" FT /protein_id="CAB51962.1" FT /translation="MYPAREVNRVFVCSCFGVTEEQVKSHAEAGACTPRQIASACKAGT FT DCGGCVRRIQALLGRGACPRRQLADQGAPVLAELPEAA" FT CDS complement(170073..171425) FT /transl_table=11 FT /gene="SCO2115" FT /gene_synonym="SC6E10.09c" FT /gene_synonym="aroH" FT /product="putative 2-dehydro-3-deoxyphosphoheptonate FT aldolase" FT /note="SC6E10.09c, aroH, probable FT 2-dehydro-3-deoxyphosphoheptonate aldolase, len: 450 aa; FT highly similar to many, especially those from plants e.g. FT SW:AROF_ARATH (EMBL:M74819), Dhs1, Arabidopsis thaliana FT phospho-2-dehydro-3-deoxyheptonate aldolase 1 precursor FT (525 aa), fasta scores; opt: 1633 z-score: 1839.4 E(): 0, FT 53.8% identity in 437 aa overlap. The N-terminus is similar FT (but not identical) to the SW:AROF_STRCO, AroH, FT Streptomyces coelicolor 2-dehydro-3-deoxyphosphoheptonate FT aldolase N-terminal sequence determined from purified FT protein (TVNAKTSPSA GNTDDPLQAP S). Similar to TR:O52308 FT (EMBL:AF035756) Streptomyces sp. FT 2-dehydro-3-deoxyphosphoheptonate aldolase (fragment) (448 FT aa) (90.4% identity in 448 aa overlap). Also similar to FT TR:Q9Z4X1 (EMBL:AL035654), Aro, S.coelicolor probable FT 2-dehydro-3-deoxyheptonate aldolase (484 aa) (53.6% FT identity in 440 aa overlap). An alternative start codon is FT present at codon 3. Contains Pfam match to entry PF01474 FT DAHP_synth_2, Class-II DAHP synthetase family" FT /db_xref="GOA:P80574" FT /db_xref="InterPro:IPR002480" FT /db_xref="UniProtKB/Swiss-Prot:P80574" FT /protein_id="CAB51963.1" FT /translation="MTVNAKTSPSAGNTWRDLPAAQQPEYPDTEALRAVIADLESYPPL FT VFAGECDQLRARMAAVAKGEAFLLQGGDCAEAFDAVSADHIRNKLKTLLQMGAVLTYAA FT SVPVVKVGRIAGQYSKPRSKPTETRDGVTLPTYRGDSVNGFDFTEAARIPDPERLKRMY FT HASASTLNLVRAFTTGGYADLRQVHAWNQDFVKSSPSGQRYEQLAREIDNALNFMRACG FT TDPAEFQTVEFFSSHEALLLDYESALTRVDSRTGQLYDVSGHMVWIGERTRQLDHAHIE FT FASRIRNPIGIKLGPSTTAEEALQYIERLDPEREPGRLTFIVRMGADKIRDKLPELVEK FT VTASGATVAWITDPMHGNTYEAASGHKTRRFDDVLDEVKGFFEVHKSLGTHPGGIHVEL FT TGDDVTECVGGGDEIFVDDLHQRYETACDPRLNRSQSLDLAFLVAEMYRDQ" FT misc_feature complement(170094..171410) FT /note="Pfam match to entry PF01474 DAHP_synth_2, Class-II FT DAHP synthetase family, score 928.30, E-value 2.2e-275" FT CDS 171596..174427 FT /transl_table=11 FT /gene="SCO2116" FT /gene_synonym="SC6E10.10" FT /product="putative secreted protein" FT /note="SC6E10.10, possible secreted protein, len: 943 aa; FT unknown function, similar in parts to bacterial AmpD FT (amidase) proteins e.g. TR:Q46959 (EMBL:U40805), AmpD, FT Enterobacter cloacae anhydro-N-acetylmuramyl-tripeptide FT amidase (187 aa), fasta scores; opt: 208 z-score: 224.7 FT E(): 3.4e-05, 37.4% identity in 123 aa overlap. Similar to FT parts of others from S.coelicolor e.g. SCH35.49C FT (EMBL:AL078610) S.coelicolor hypothetical protein (410 aa) FT (37.7% identity in 252 aa overlap). Contains possible FT N-terminal signal sequence. The C-terminus contains 5x FT degenerate 50 aa repeats" FT /db_xref="GOA:Q9S2M7" FT /db_xref="InterPro:IPR013517" FT /db_xref="UniProtKB/TrEMBL:Q9S2M7" FT /protein_id="CAB51964.1" FT /translation="MSAEHRRNRNKKRLLVYGVASAVVVAATTGTLALASPGLLGLDAD FT QAAAAPAGARLQSEFEQAAEEFDVPQSVLMAVSYRQTRWEDHDGLPSTTGAYNVMGLTD FT VDADSLENDGAAEEREHRLEHMNRSGDPVVEKHFDADKALESLDEKPVDTDDPRLHTLD FT EAAGLIDASTEKVQSDTGESIRAGAALLAQYQKDATGSLPEDPGAWYPAVARASQAPDT FT KGAQLFAQRVFESIKTGEQRVTADGQALTLPADPAVKPKKTTDLELAAASAAPAPECPS FT GLNCDFRPAAYKQNGGIDDWGNYNVASRPTAGHEITSIVIHDTEGSYSSALGVFQNSLS FT YASAHYLIRASDGLVTQMVETKNEAWHAANKTLNMHSIGIEHEGYAIKDGSWYTEPQYE FT SSAALVKYLAGKYDIPLDREHILGHDEVPGVLDGNVKSQHWDPGPFWDWNHYMGLLGAP FT TGAGGAGGPYKTGQVIRVVPPFTTANQPKITNGGSSVPAQPANFTYVYTSPSTGSATLT FT DPYLGSQTWTEGWNWGNKVLAGGEYVVAEARRDWTAIWYGGKKAWFSNRNGGFATAVGT FT PDVVTAKAGASSVPVYGRAYPEDGAYAGTGVPVQSRNNESLTKYGVLAGQKYALAGGAM FT KGSYYNSGNIDGSGEGSRTVVVGDTSYYPIRFNHRIGYVRTADVQLVKGTAPDPGTDRY FT NLLGRDASGVLWQYQGTGSASSPFFGRFRVGGGWDTYNAITTLTALRADGTGDMVARDK FT SGVLWYYKGSGNPSAPFERRTKVGGGWSVYDVITGARDITGDGKPDLIARDKSGGLWLY FT QGTGNASAPFRTKSAIGSGWNTYTALTDTGDLTGDGRPDLVARDKNGVLWLYKGKANAA FT SPYERRTSIGSGWNTYNVLRGPSDLNRDGRPDLVGRDKNGVLYFYKGTGSASAPFERRT FT TIGTGWNTYGLII" FT repeat_region 173687..174424 FT /note="5x approx. 150 bp degenerate repeats" FT CDS 174703..176607 FT /transl_table=11 FT /gene="SCO2117" FT /gene_synonym="SC6E10.11" FT /gene_synonym="trpE1" FT /product="putative anthranilate synthase" FT /note="SC6E10.11, trpE1, probable anthranilate synthase, FT len: 634 aa; highly similar to many anthranilate synthases FT e.g. TR:O30589 (EMBL:AF012627), TrpE, Streptomyces FT venezuelae anthranilate synthase (623 aa), fasta scores; FT opt: 3108 z-score: 3257.7 E(): 0, 80.0% identity in 620 aa FT overlap. Anthranilate synthases may have one or two FT components. This protein is similar at the C-terminus to FT TR:Q9Z4W8 (EMBL:AL035654), TrpG, S.coelicolor probable FT anthranilate synthase component II (200 aa) (32.7% identity FT in 202 aa overlap) and centrally to TR:Q9Z4W7 FT (EMBL:AL035654), trpE2, S.coelicolor probable anthranilate FT synthase component I (511 aa) (30.6% identity in 301 aa FT overlap) which appear to constitute a two-component type FT enzyme. Contains two Pfam matches to entry PF00425 FT chorismate_bind, chorismate binding enzyme and Pfam match FT to entry PF00117 GATase, Glutamine amidotransferase FT class-I" FT /db_xref="GOA:Q9S2M6" FT /db_xref="HSSP:1I1Q" FT /db_xref="InterPro:IPR005801" FT /db_xref="UniProtKB/TrEMBL:Q9S2M6" FT /protein_id="CAB51965.1" FT /translation="MTPLDSLLTGTRPFALLRRRAPGRDHDVVELLLGPVTEHGRLADL FT PDEGLALVPFRQIRERGFDVRDDGTPLLVLTPEERHDIPLGEALAQLPAHEVRVEGGGF FT DVGDEEYARIVGRVLDEEIGRGEGANFVIRRTYEGRIPGFGRADALALFRRLLAGERGA FT YWTFVVHTGDRTLVGASPEVHVRMSGGTVVMNPISGTYRYPAEGPTPEHLLDFLADGKE FT IEELSMVVDEELKMMCTVGDMGGVVVGPRLKEMAHLAHTEYELRGKSSLDAREVLRETM FT FAATVTGSPVQNACRVIERHETGGRGYYAGALALLGRDPGDGPGQPGPQTLDSPILIRT FT ADIDAAGRLRVPVGATLVRGSDPAGEVAETHAKAAGVLAALGVRPSRPRTEAGRPRLAD FT DPRVRAALDGRRASLAPFWLRMQEPSAELSGHALVVDAEDTFTAMLAHVLRSSGLAVSV FT RRYDEPGLREAVLGHQGGPVVLGPGPGDPSDPADPKMRFLRSLTAEVLGANRHGVLGVC FT LGHELIAAELGLDIVRKEVPYQGAQTEIDLFGRPETVGFYNSFTARCDDGTARELAARG FT IEVSRSAAGEVHALRGGGFAGVQFHPESVLTLNGTAIVRELAGQLRGTSTFSERRPSR" FT misc_feature 175021..175302 FT /note="Pfam match to entry PF00425 chorismate_bind, FT chorismate binding enzyme, score 29.80, E-value 1e-07" FT misc_feature 175504..175845 FT /note="Pfam match to entry PF00425 chorismate_bind, FT chorismate binding enzyme, score 56.90, E-value 1.4e-15" FT misc_feature 175993..176562 FT /note="Pfam match to entry PF00117 GATase, Glutamine FT amidotransferase class-I, score 41.00, E-value 1.1e-10" FT CDS complement(176559..177554) FT /transl_table=11 FT /gene="SCO2118" FT /gene_synonym="SCE10.12c" FT /gene_synonym="dldh2" FT /product="putative D-lactate dehydrogenase" FT /note="SCE10.12c, dldh2, probable D-lactate dehydrogenase, FT len: 331 aa; highly similar to many members of the D-isomer FT specific 2-hydroxyacid dehydrogenases family, especially FT lactate dehydrogenases e.g. SW:LDHD_ECOLI (EMBL:U36928), FT LdhA, Escherichia coli D-lactate dehydrogenase (329 aa), FT fasta scores; opt: 843 z-score: 1010.7 E(): 0, 44.4% FT identity in 320 aa overlap. Similar to other dehydrogenases FT from S.coelicolor e.g. SC66T3.05 (EMBL:AL079348), dldh, FT S.coelicolor probable D-lactate dehydrogenase 337 aa) FT (36.3% identity in 325 aa overlap). Contains Pfam match to FT entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid FT dehydrogenases" FT /db_xref="GOA:Q9S2M5" FT /db_xref="HSSP:1J4A" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9S2M5" FT /protein_id="CAB51966.1" FT /translation="MEILAFGVQADEKPLIERAFRDHEDVRCLDVFLNEDTAPIAAGHE FT IVSTSVNADLGAAVLEILAAGGTRMVAQRSTGFNNVDLDTADRLGMTVARVSYYSPHSV FT AEFAWALAMAVNRRIVRASIRTRDFDFRLDGLMGRDLHGRTAGVLGTGKIGEAFARIAH FT GFGMRLLGWDVAENPACAELGMRYVAKDELLARSDLITLHVPLMAETRHLIDATALKAM FT RDDAILINSSRGGLIDTAALVGELRAGRFAGVGLDVYEAEAGLFFLDKSLEAVEDDTLA FT RLVTFPNVLVTSHQAYYTEDAVGQIVGTTVRNVLDYREGRRSENVLVPRS" FT misc_feature complement(176673..177326) FT /note="Pfam match to entry PF00389 2-Hacid_DH, D-isomer FT specific 2-hydroxyacid dehydrogenases, score 262.70, FT E-value 2.9e-107" FT misc_feature complement(177579..178770) FT /note="sequence equivalent to Streptomyces coelicolor FT phosphofructokinase ATP-PFK gene (EMBL:U51728) from 56 to FT 1247" FT CDS complement(177638..178666) FT /transl_table=11 FT /gene="SCO2119" FT /gene_synonym="SC6E10.13c" FT /gene_synonym="pfkA" FT /product="6-phosphofructokinase" FT /note="SC6E10.13c, pfkA, 6-phosphofructokinase, len: 342 FT aa; previously sequenced as TR:O08333 (EMBL:U51728) FT Streptomyces coelicolor phosphofructokinase ATP-PFK (342 FT aa). There are some differences in the flanking nucleotides FT between this and the previous sequence (EMBL:U51728), but FT the proteins remain 100% identical. Contains Pfam match to FT entry PF00365 PFK, Phosphofructokinase and S00433 FT Phosphofructokinase signature" FT /db_xref="GOA:O08333" FT /db_xref="HSSP:3PFK" FT /db_xref="InterPro:IPR015912" FT /db_xref="UniProtKB/Swiss-Prot:O08333" FT /protein_id="CAB51967.1" FT /translation="MKVGVLTGGGDCPGLNAVIRAVVRKGVQEYGYDFTGFRDGWRGPL FT EGDTVPLDIPAVRGILPRGGTVLGSSRTNPLKQRDGIRRIKDNLAALGVEALITIGGED FT TLGVATRLADEYGVPCVGVPKTIDNDLSATDYTFGFDTAVGIATEAIDRLHTTAESHMR FT VLVVEVMGRHAGWIALHSGLAGGANVILIPEQRFDVEQVCSWVTSRFRASYAPIVVVAE FT GAMPRDGDMVLKDESLDSYGHVRLSGVGEWLAKQIEKRTGNEARTTVLGHVQRGGTPSA FT FDRWLATRFGLHAVDCVHDGDFGKMVALRGTDIVRVPIAEATARLKTVDPALYEEVGVF FT FG" FT misc_feature complement(177767..178663) FT /note="Pfam match to entry PF00365 PFK, FT Phosphofructokinase, score 330.00, E-value 1.7e-120" FT misc_feature complement(177815..177871) FT /note="PS00433 Phosphofructokinase signature" FT CDS complement(178718..179365) FT /transl_table=11 FT /gene="SCO2120" FT /gene_synonym="SC6E10.14c" FT /product="putative two-component system regulator" FT /note="SC6E10.14c, probable two-component system regulator, FT len: 215 aa; similar to many e.g. SW:DEGU_BACBR FT (EMBL:M21658), DegU, Bacillus brevis transcriptional FT regulatory protein for the production of extracellular FT proteases (236 aa), fasta scores; opt: 443 z-score: 510.2 FT E(): 4.3e-21, 36.5% identity in 219 aa overlap. Similar to FT others from S.coelicolor e.g. SCH10.18C (EMBL:AL049754) FT S.coelicolor probable two-component system regulator (228 FT aa) (37.9% identity in 214 aa overlap). Contains probable FT helix-turn-helix motif at aa 169-190 (Score 1764, +5.19 FT SD). Contains Pfam matches to entry PF00072 response_reg, FT Response regulator receiver domain and to entry PF00196 FT GerE, Bacterial regulatory proteins, luxR family. Contains FT PS00622 Bacterial regulatory proteins, luxR family FT signature" FT /db_xref="GOA:Q9S2M4" FT /db_xref="HSSP:1RNL" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9S2M4" FT /protein_id="CAB51968.1" FT /translation="MVVDDHPMWRDAVARDLAESGFDVVATASDGDQAVRRARAAAPDV FT LVLDLNLPGRPGVQVCKEAVGTDPKLRVLVLSASGEHADVLEAVKSGATGYLLKSASTE FT ELRDAVRRTAAGDPVFTPGLAGLVLGEYRRLASEPAPAAGTDDPGAPRLTDRETEVLRL FT VAKGLSYKQIAERLVISHRTVQNHVQNTLGKLQLHNRVELVRYAIERGLDDA" FT misc_feature complement(178721..178918) FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 90.60, E-value FT 3.2e-23" FT misc_feature complement(178784..178867) FT /note="PS00622 Bacterial regulatory proteins, luxR family FT signature" FT misc_feature complement(179036..179365) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 107.70, E-value 2.3e-28" FT CDS complement(179433..180674) FT /transl_table=11 FT /gene="SCO2121" FT /gene_synonym="SC6E10.15c" FT /product="putative two-component system sensor kinase" FT /note="SC6E10.15c, possible two-component system sensor FT kinase, len: 413 aa; similar to many e.g. SW:DEGS_BACBR FT (EMBL:L15444), DegS, Bacillus brevis sensor protein (386 FT aa), fasta scores; opt: 174 z-score: 193.4 E(): 0.0019, FT 23.4% identity in 278 aa overlap. The N-terminal approx. FT 100 aa are different from many of the putative homologues. FT Similar to others from S.coelicolor e.g. SCE126.08C FT (EMBL:AL049630) S.coelicolor possible two component sensor FT kinase (401 aa) (26.6% identity in 323 aa overlap). FT Contains hydrophobic, possible membrane-spanning regions in FT the N-terminal half" FT /db_xref="GOA:Q9S2M3" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9S2M3" FT /protein_id="CAB51969.1" FT /translation="MARRERVMRMSVEQPLWRALAGYRVLTMLYAIGFFATAYSGFARP FT WLAVAYYAVLFVWTLATLPKLANAASCTKRFLTADLTIALAGILLTPFADAHQRVADGG FT PTLPSIWTAGSVLAFAVKGGWRWAAVASTLVAVANLVERGTPARDTVHNVILVWVASIA FT IGYVVEVARASERTLARALEIEAATRERERLARDIHDSVLQVLAMVQRRGAVIGGEAAE FT LGRLAGEQEVALRTLVSGGLVPVSRVSEDAADGALVRVVEEREGTDPDGPVDLRALLAP FT YAGSLVNLADPGAPVLLAPGAARELAAAVGAALDNVREHVGERARAWILVEDEPDEVIV FT TVRDEGPGIPPGRLAEAEGEGRLGVALSIRGRLRDLGGTAELISVPGQGTEVELKAPKK FT NAGTTARGKAADHE" FT RBS complement(180681..180685) FT /note="possible RBS" FT CDS complement(180715..181503) FT /transl_table=11 FT /gene="SCO2122" FT /gene_synonym="SC6E10.16c" FT /product="conserved hypothetical protein" FT /note="SC6E10.16c, conserved hypothetical protein, len: 262 FT aa; unknown function, similar to part of TR:O33970 FT (EMBL:U80063) Streptomyces cinnamoneus hypothetical protein FT (199 aa), fasta scores; opt: 827 z-score: 903.5 E(): 0, FT 61.9% identity in 202 aa overlap and to hypothetical FT proteins from Mycobacterium tuberculosis and Mycobacterium FT leprae e.g. TR:O69572 (EMBL:AL022602) Mycobacterium leprae FT hypothetical protein (244 aa) (54.0% identity in 215 aa FT overlap). Similar to others from S.coelicolor e.g. FT TR:Q9ZBS1 (EMBL:AL034447) S.coelicolor possible FT acyltransferase (264 aa) (33.2% identity in 250 aa FT overlap). C-terminus contains 5x slightly degenerate FT KAAK(A/N)(D/E) repeats. Contains probable coiled-coil from FT 214 to 255 (42 residues) (Max score: 1.475, probability FT 0.92)" FT /db_xref="GOA:Q9S2M2" FT /db_xref="InterPro:IPR002123" FT /db_xref="UniProtKB/TrEMBL:Q9S2M2" FT /protein_id="CAB51970.1" FT /translation="MLYGAMKVTVGGSLKLAFRPWVEGLEHIPADGPAILASNHLSFSD FT SFFLPAVLDRKVTFIAKAEYFNTPGVKGRLTAAFFKGVGQLPVDRSGARGAGEAAIKSG FT IEVLERGELFGIYPEGTRSPDGRLYRGKPGGLARVALATGAPVVPVAMIDTEKIQPPGQ FT VMPKLMRPGIRIGKPLDFSRYQGMEHDRFVLRAVTDEVMYEIMKLSGQEYVDMYATAMK FT RQLAEAAKAEKAAKAEKAAKNDKAAKNDKAAKAGTDRAGT" FT repeat_region complement(180736..180825) FT /note="5x 18 bp direct repeats" FT RBS complement(181511..181515) FT /note="possible RBS" FT RBS 181626..181630 FT /note="possible RBS" FT CDS 181639..182442 FT /transl_table=11 FT /gene="SCO2123" FT /gene_synonym="SC6E10.17" FT /product="putative esterase/lipase" FT /note="SC6E10.17, possible esterase/lipase, len: 267 aa; FT similar to esterases e.g. SW:EST_BACST (EMBL:D12681), Est, FT Bacillus stearothermophilus carboxylesterase precursor (247 FT aa), fasta scores; opt: 333 z-score: 387.6 E(): 2.9e-14, FT 32.7% identity in 251 aa overlap" FT /db_xref="GOA:Q9S2M1" FT /db_xref="InterPro:IPR012354" FT /db_xref="UniProtKB/TrEMBL:Q9S2M1" FT /protein_id="CAB51971.1" FT /translation="MSVLPGAEPFRHEGGDVGVLLCHGFTGSPQSLRPWARYLAARGLT FT VSLPLLPGHGTRWQDMQVTGWQDWYAEVDRELRALRERCERVFVAGLSMGGALALRLAA FT KHGDAVSGVVVVNPANRMHGVAQHALPVLRHLVPATKGIASDIAKPLSTELGYDRVPLH FT SAHSLRAFFRLADGDLPQVTQPLLLLRSPQDHVVPPADSARILGRVSSTDVTEILLEQS FT YHVATLDHDADRIFAESVAFIGRLAPGSVGEPESGLGKEGTAAGG" FT CDS 182435..183052 FT /transl_table=11 FT /gene="SCO2124" FT /gene_synonym="SC6E10.18" FT /product="putative membrane protein" FT /note="SC6E10.18, putative membrane protein, len: 205 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. The FT amino acid composition of this CDS is unusual, being FT Pro-rich and having a very acidic N-terminus. Contains FT probable coiled-coil from 1 to 29 (29 residues) (Max score: FT 1.455, probability 0.88). Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9S2M0" FT /protein_id="CAB51972.1" FT /translation="MAEHDSDREDREERDLEREHREGRERAADGGPEAQDAPFDEDAAW FT ASIVAGYGEEPPDPPGAKPFKSVEDLALLEPEVNDEKPSADRPSSDRPLGSSVAFAPGV FT GPRDHAPAEPSDDDFDADDEGHFVPPEPPPLPETDPTSKFAWLGVLGGPVLLLLAVVLG FT WDMTWWLTTLSIGGFLGGFATLVVRMRTGDEDDDDPGRGAVV" FT CDS complement(183077..183838) FT /transl_table=11 FT /gene="SCO2125" FT /gene_synonym="SC6E10.19c" FT /product="hypothetical protein" FT /note="SC6E10.19c, hypothetical protein, len: 362 aa; FT unknown function, weak similarity to Y63D3A.4 FT (EMBL:AL032652) Caenorhabditis elegans hypothetical protein FT (362 aa), fasta scores; opt: 172 z-score: 209.3 E(): FT 0.00025, 28.7% identity in 181 aa overlap" FT /db_xref="InterPro:IPR005135" FT /db_xref="UniProtKB/TrEMBL:Q9S2L9" FT /protein_id="CAB51973.1" FT /translation="MATSLPALPNSRTEPDGSAVIRVLSYNIRSLRDDTDALARVIKAC FT APDLVLLQEAPRFFRWRKKITRLAAAGDLVLLSGGGTAAGPALLCSLRATVERTEDVLL FT PLTPGRHRRGIAAAVVRIGGARIGVLSSHLSLDADERHEQAGLLLDHLAALGVKHAVAG FT GDLNERPGGRTFRRLGEGLRDCWTAAPWGGEYTFPATAPDRRIDAVFVTEGIEVLGCGV FT PSGLAGVAEDDLRAATDHLPVLTALRVPATA" FT misc_feature complement(183861..186664) FT /note="sequence equivalent to S.coelicolor glk gene for FT glucose kinase (EMBL:X65932) from 1 to 2804" FT CDS complement(183983..184936) FT /transl_table=11 FT /gene="SCO2126" FT /gene_synonym="SC6E10.20c" FT /gene_synonym="glk" FT /product="glucokinase" FT /note="SC6E10.20c, glk, glucokinase, len: 317 aa; FT previously sequenced as SW:GLK_STRCO (EMBL:X65932), Glk, FT Streptomyces coelicolor glucokinase (317 aa), identical to FT this sequence. Similar to other ROK-family proteins from FT S.coelicolor e.g. TR:O69941 (EMBL:AL023862) S. coelicolor FT hypothetical ROK family protein (403 aa) (34.7% identity in FT 317 aa overlap). Pfam match to entry PF00480 ROK, ROK FT family and PS01125 ROK family signature" FT /db_xref="GOA:P0A4E1" FT /db_xref="InterPro:IPR004654" FT /db_xref="UniProtKB/Swiss-Prot:P0A4E1" FT /protein_id="CAB51974.1" FT /translation="MGLTIGVDIGGTKIAAGVVDEEGNILSTHKVPTPTTPEAIVDAIA FT SAVEGARVGHEIVAVGIGAAGYVNRQRSTVYFAPNIDWRQEPLKEKVEARVGLPVVVEN FT DANAAAWGEYKFGGGKGHRNVICITLGTGLGGGIIIGNKLRRGHFGVAAEFGHIRMVPD FT GLLCGCGSQGCWEQYASGRALVRYAKQRANATPERAEVLLALGDGTPDGIEGKHISVAA FT RQGCPVAVDSYRELARWAGAGLADLASLFDPSAFIVGGGLSDEGDLVLDPIRKSYKRWL FT VGGNWRPVADVIAAQLGNKAGLVGAADLAREPDPIM" FT misc_feature complement(184385..184921) FT /note="Pfam match to entry PF00480 ROK, ROK family, score FT 328.50, E-value 1.3e-96" FT misc_feature complement(184466..184549) FT /note="PS01125 ROK family signature" FT CDS complement(184991..185566) FT /transl_table=11 FT /gene="SCO2127" FT /gene_synonym="SC6E10.21c" FT /product="hypothetical protein" FT /note="SC6E10.21c, hypothetical protein, len: 191 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Previously sequenced as SW:YGL2_STRCO (EMBL:X65932) FT Streptomyces coelicolor hypothetical protein (191 aa), FT identical to this sequence" FT /db_xref="GOA:P40182" FT /db_xref="UniProtKB/Swiss-Prot:P40182" FT /protein_id="CAB51975.1" FT /translation="MSEELPPSEAPRPDEADAVDETRATGETRGAAQEPGASDADAWAT FT ACAEDLEAEKARRRAAYGPPPGSAAEELRRLVDTVADKLSGLQSPLLGQVAGPAAQQVV FT RQVVQQAKAAVEPVIERNPDLFDHLAAAGGELLAAYRSAVQNQERRWTTGDTAPKDPSD FT PRDLDERGTDGRDEGDGGTGPGQRIDLD" FT CDS complement(185637..186911) FT /transl_table=11 FT /gene="SCO2128" FT /gene_synonym="SC6G10.01c" FT /gene_synonym="SC6E10.22c" FT /product="hypothetical protein" FT /note="SC6G10.01c, partial CDS, unknown, len: >40aa;" FT /note="SC6E10.22c, hypothetical protein, len: 390 aa; FT unknown function, similar to the N-terminal half of FT anion-transporter ATPases e.g. TR:O50593 (EMBL:AB004659), FT arsA, Acidiphilium multivorum plasmid pKW301 arsenite FT activated ATPase of translocating ATPase (583 aa), fasta FT scores; opt: 190 z-score: 208.0 E(): 0.00029, 27.3% FT identity in 267 aa overlap. Previously partially sequenced FT as SW:YGL1_STRCO (EMBL:X65932) Streptomyces coelicolor FT hypothetical protein (341 aa), identical to this sequence" FT /db_xref="GOA:P40181" FT /db_xref="InterPro:IPR003348" FT /db_xref="UniProtKB/Swiss-Prot:P40181" FT /protein_id="CAD55294.1" FT /translation="MARAGRSGTPHRRAANPPPHRHPGTADAPVPFTPMRTLLITGPGG FT TGRTTVAAATALTAARQGTRTLVLGTDRDDTLGAALGVRTGPAPTSVEPGLTAWRPDAA FT QGFRDALAALQDRAASALDLLGAARLDPQELTPLPGADDLALLRALREAALAEAHDLLV FT VDLPPAPRALALLAAPEELRRALRRLLPPERQAARALRPVLGRLAGVPMPTEALYEAAA FT RWDLELAAAESVLADRNTVVRLVAEPGPAGADAVRTTTLGLALRGLRTDLLVANRVLPE FT DTPADSWLSGPLAQQRKTLEEWRGAYDVRAVAHLGHDPRGTDDLAALAVPGVNPDASPV FT EWPVTDRLAEDGVLVWHIPLPGAVREELDLVRRGDELAVAAGPFRRTVPLPSALRRCTV FT DGAALRDGTLAVRFAPDPELWPRGR" FT CDS complement(187023..187457) FT /transl_table=11 FT /gene="SCO2129" FT /gene_synonym="SC6G10.02c" FT /product="conserved hypothetical protein" FT /note="SC6G10.02c, hypothetical protein, len: 144 aa; FT similar to hypothetical proteins from Mycobacterium eg. FT TR:O53519 (EMBL:AL021957) hypothetical protein from FT Mycobacterium tuberculosis (144 aa) fasta scores; opt: 479, FT z-score: 620.2, E(): 3.1e-27, (49.0% identity in 143 aa FT overlap)" FT /db_xref="InterPro:IPR005031" FT /db_xref="UniProtKB/TrEMBL:Q9X7Y8" FT /protein_id="CAB39856.1" FT /translation="MAEHTSSSITIEAAPADVMAVIADFARYPDWTGEVKEAQVLATDE FT QGRAEQVRLVMDAGAIKDDQTLGYTWTGEHEVSWTLVKSQMLRSLDGSYLLRPAGTGTE FT VTYRLTVDVKIPMLGMIKRKAEKVIIDRALAGLKKRVESK" FT CDS complement(187595..188392) FT /transl_table=11 FT /gene="SCO2130" FT /gene_synonym="SC6G10.03c" FT /product="hypothetical protein" FT /note="SC6G10.03c, hypothetical protein, len: 265 aa; weak FT similarity to many eg. TR:P95860 (EMBL:Y08256) Sulfolobus FT solfataricus hypothetical protein ORF CO6013 (309 aa) fasta FT scores; opt: 152, z-score: 186.9, E(): 0.0041, (24.8% FT identity in 270 aa overlap)." FT /db_xref="GOA:Q9X7Y9" FT /db_xref="InterPro:IPR004843" FT /db_xref="UniProtKB/TrEMBL:Q9X7Y9" FT /protein_id="CAB39857.1" FT /translation="MAPTPPRNTSTRVHVVSDVHGNARDLARAGDGADALICLGDLVLF FT LDYADHSRGIFPDLFGVANADRIVALRTARRFEEAREFGRRLWAEAGGEPRELIERAVR FT KQYAELFAAFPTPTYATYGNVDVPPLWPEYAGPGTTVLDGERVEIGGRVFGFVGGGLRT FT PMNTPYEISDEEYAAKIEAVGEVDVLCTHIPPEVPELVYDTVARRFERGSRALLDAIRR FT TRPRYALFGHVHQPLVRRMRVGATECVNVGHFASSGRPWALEW" FT CDS 188703..190499 FT /transl_table=11 FT /gene="SCO2131" FT /gene_synonym="SC6G10.04" FT /product="putative long chain fatty acid CoA ligase" FT /note="SC6G10.04, probable long chain fatty acid CoA FT ligase, len: 598 aa; similar to many e.g. TR:E1359128 FT (EMBL:AL034443) putative long chain fatty acid CoA ligase FT from Streptomyces coelicolor (608 aa) fasta scores; opt: FT 1347, z-score: 1506.7, E(): 0, (51.3% identity in 608 aa FT overlap) and SW:LCFB_RAT long chain fatty acid CoA ligase FT from Rattus norvegicus (Rat) (699 aa) fasta scores; opt: FT 568, z-score: 634.7, E(): 4.7e-28, (30.2% identity in 589 FT aa overlap). Contains Pfam match to entry PF00501 FT AMP-binding, AMP-binding enzyme and Prosite match to FT PS00455 Putative AMP-binding domain signature." FT /db_xref="GOA:Q9X7Z0" FT /db_xref="HSSP:1LCI" FT /db_xref="InterPro:IPR000873" FT /db_xref="UniProtKB/TrEMBL:Q9X7Z0" FT /protein_id="CAB39858.1" FT /translation="MREFSLPALYEVPADGNLTDIVRRNAAQHPDVAVIARKVGGVWQD FT VTARAFLAEVHSAAKGLIASGVQPGDRVGLMSRTRYEWTLLDFAIWSAGAITVPVYETS FT SPEQVQWILGDSGATACVVESAGHAAAVESVREQLPALKNVWQIDAGAVEELGRLGQDV FT TDRTVEERGSIAKADDPATIVYTSGTTGRPKGCVLTHRSFFAECGNVVERLRPLFRTGE FT CSVLLFLPLAHVFGRLVQVAPMIAPIKLGNVPDIKNLTDELAAFRPTLILGVPRVFEKV FT YNSARAKAQADGKGKIFDKAADTAIAYSKALDAPSGPSVGLKIKHKVFDKLVYSKLRTV FT LGGRGEYAISGGAPLGERLGHFFRGIGFTVLEGYGLTESCAATAFNPWDRQKIGTVGQP FT LPGSVVRIADDGEVLLHGEHLFKEYWNNPGATAEALADGWFHTGDIGTLDEDGYLRITG FT RKKEIIVTAGGKNVAPAVMEDRIRAHALVAECMVVGDGRPFVGALVTIDEEFLGRWCAE FT HGKPAGSTAVSLREDPELLAAIQDAVDDGNAAVSKAESVRKFRVLGAQFTEDSGHLTPS FT LKLKRNVVAKDYADEIEAIYSK" FT misc_feature 188841..190178 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score -28.50, E-value 3.2e-13." FT misc_feature 189249..189284 FT /note="PS00455 Putative AMP-binding domain signature." FT CDS complement(190487..191725) FT /transl_table=11 FT /gene="SCO2132" FT /gene_synonym="SC6G10.05c" FT /product="putative glycosyl transferase" FT /note="SC6G10.05c, possible glycosyl transferase, len: 412 FT aa; similar to TR:O53522 (EMBL:AL021957) hypothetical FT protein from Mycobacterium tuberculosis (399 aa) fasta FT scores; opt: 1276, z-score: 1452.2, E(): 0, (51.9% identity FT in 391 aa overlap) and SW:WCAL_SALTY putative colanic acid FT biosynthesis glycosyl transferase from the Rfb (O antigen) FT gene cluster of Salmonella typhimurium (406 aa) fasta FT scores; opt: 291, z-score: 334.2, E(): 2.6e-11, (29.0% FT identity in 300 aa overlap). Contains Pfam match to entry FT PF00534 Glycos_transf_1, Glycosyl transferases group 1" FT /db_xref="GOA:Q9X7Z1" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q9X7Z1" FT /protein_id="CAB39859.1" FT /translation="MRKTLIVTNDFPPRPGGIQAFLHNMALRLDPERLVVYASTWKRGR FT EGIEATAAFDAEQPFTVVRDRTTMLLPTPGATRRAVGLLREHGCTSVWFGAAAPLGLMA FT PALRRAGAERLVATTHGHEAGWAQLPAARQLLRRIGESTDTITYLGEYTRSRIAGALTP FT GAAARMVQLPPGVDEKTFHPASGGDEVRARLGFTDRPVVVCVSRLVPRKGQDTLIRAMP FT RILAAEPDAVLLIVGGGPYEKDLRRLAEETGVAAAVHFTGAVPWSELPAHYGAGDVFAM FT PCRTRRGGLDVEGLGIVYLEASATGLPVVAGDSGGAPDAVLDGETGWVVRGEDPNESAD FT RITTLLADPELRRRMGERGRAWVEEKWRWDLLAEHLRTLLQGGSAARARQATDNVGPPT FT NRTRHPGRRPYLE" FT misc_feature complement(190640..191113) FT /note="Pfam match to entry PF00534 Glycos_transf_1, FT Glycosyl transferases group 1, score 86.70, E-value FT 1.1e-23." FT CDS 191882..193147 FT /transl_table=11 FT /gene="SCO2133" FT /gene_synonym="SC6G10.06" FT /product="putative integral membrane protein" FT /note="SC6G10.06, possible integral membrane protein, len: FT 421 aa; similar to hypothetical proteins eg. TR:P71708 FT (EMBL:Z80775) hypothetical protein from Mycobacterium FT tuberculosis fasta scores; opt: 230, z-score: 251.3, E(): FT 1.1e-06, (27.1% identity in 417 aa overlap). Contains FT possible membrane spanning hydrophobic regions" FT /db_xref="InterPro:IPR016570" FT /db_xref="UniProtKB/TrEMBL:Q9X7Z2" FT /protein_id="CAB39860.1" FT /translation="METRDAGRSRMWLPTVWGATRLVLLLFVLKVLVFPGPDVTGDVSV FT IYRDWADVLRTGTFPLNDVTWQYPPAAAFAVLSPGLLPFLEYATAFFVLAWVTDAAVLA FT LLWHAGRGTGRSPRGAWVWVAGVPLLGPTVYARYDVMVTAVAVAALLAAGRHPRVAGAL FT AAVGALLKVWPALVLVGMRGRGPWVAAAVSGAGLAALFAVSMPGAFAFLTFQRERGVEV FT ESLGSLVFHVARHFGWEGGVLLNYGSMEFLGPHVDTVGTVSLGLSAVAFGWLLLWRVRA FT SRSASHRFAAHTAADAAFVAVLMFTVTSRVISPQYLVWLVGLGAVCRCFRASRMRVPVA FT LVLAATPLTALEFPLLFADVVASTPFGITLLSVRNGLLVAATLLAARALWRGTVRGGTP FT APAGQPAPLTRAAPADTPTGAP" FT CDS complement(193175..194332) FT /transl_table=11 FT /gene="SCO2134" FT /gene_synonym="SC6G10.07c" FT /product="hypothetical protein" FT /note="SC6G10.07c, unknown, len: 385aa; similar to FT TR:O53523 (EMBL:AL021957) hypothetical protein from FT Mycobacterium tuberculosis (257 aa) fasta scores; opt: 225, FT z-score: 262.9, E(): 2.4e-07, (33.1% identity in 254 aa FT overlap)." FT /db_xref="UniProtKB/TrEMBL:Q9X7Z3" FT /protein_id="CAB39861.1" FT /translation="MALCLLLVALVGCGGRTATDRSSTDVQRVLDRRAAAVLAHDAAAY FT ARTGTATGFGNLSAIPLAAWSYRVRGVERSGDTATADVELRYRVRGYDRGPVSAGRTVR FT LSRDGTAGTWTVDSDRPAKESGQQPWDQGAVRVVRGTHSLVLGVGQSTTALRRFADLAD FT RAVPAVSDAWDGDWSRRVVVVVPRSLEGMAGLLGSPASSYRGIAAVTTGETGGREHAPA FT DRIIVNPDAYGLLGSLGKQVVLTHETTHVATRADTTSATPLWLSEGYADWVGYRGSGRT FT AAQAAPELAGAVAEGRAPARLPTDEDFGFTADAEALARAYEGGWLACRMIAEQWGEDRL FT DAFYRSVGTHDDRAGAVEAALHEVLGTTPDDFTARWRSYLRTRLG" FT CDS complement(194454..195470) FT /transl_table=11 FT /gene="SCO2135" FT /gene_synonym="SC6G10.08c" FT /product="putative secreted protein" FT /note="SC6G10.08c, possible secreted protein, len: 338 aa; FT similar to TR:O69580 (EMBL:AL022602) putative secreted FT protein from Mycobacterium leprae (374 aa) fasta scores; FT opt: 382, z-score: 384.3, E(): 4.2e-14, (32.4% identity in FT 358 aa overlap). Also similar to several examples of FT Listeria P60 a major extracellular protein involved in the FT invasion of non-professional phagocytic cells eg. FT SW:P60_LISIV from Listeria ivanovii (524 aa) fasta scores; FT opt: 337, z-score: 338.3, E(): 1.5e-11, (29.1% identity in FT 309 aa overlap). Contains Pfam match to entry PF00877 FT NLPC_P60, NLP/P60 family and the C-terminus, a probable FT membrane spanning hydrophobic region towards the N-terminus FT and two possible coiled coil regions. NOTE: highly similar FT to upstream gene, 6G10.09c, indicating a duplication event; FT fasta scores: opt: 1042, z-score: 843.1, E(): 0, (49.9% FT identity in 339 aa overlap)." FT /db_xref="InterPro:IPR000064" FT /db_xref="UniProtKB/TrEMBL:Q9X7Z4" FT /protein_id="CAB39862.1" FT /translation="MGSHRRLAPSGFDRGSTAAVGLLSVAAALLGAVPATAAPHDDRRA FT EVDRLHTEAEQATEAYNKADARTDALREEVTTAQESIARQQERVNTMRDALGSLAGAQY FT RSGGIDPSLALLLSAEPDDYLDRASVLDRITTRQAGELRELQQAMRDLAQDRAEAARKL FT TELERGRKAVAAHKKTVERKLAKARALLAALPDDERTAYQRGSRSGREDLTALAGAAAP FT ASGRAGAAFAAARSALGKPYVWGANGPSGFDCSGLTQWSYAQAGVGIPRTSQAQTGAGR FT HVSLAEARPGDLVAYRDDASHIGMYAGNGQVIHAPYPGAPVRYDPVGMMPISSITRV" FT misc_feature complement(194457..194771) FT /note="Pfam match to entry PF00877 NLPC_P60, NLP/P60 FT family, score 126.60, E-value 4.5e-34." FT CDS complement(195707..196750) FT /transl_table=11 FT /gene="SCO2136" FT /gene_synonym="SC6G10.09c" FT /product="putative secreted protein" FT /note="SC6G10.09c, possible secreted protein, len: 347 aa; FT similar to TR:E1370194 (EMBL:Y13601) hypothetical protein FT from Streptomyces lividans (250 aa) fasta scores; opt: 371, FT z-score: 366.3, E(): 4.3e-13, (31.4% identity in 229 aa FT overlap). Also similar to several examples of Listeria P60 FT a major extracellular protein involved in the invasion of FT non-professional phagocytic cells e.g. SW:P60_LISMO from FT Listeria monocytogenes (484 aa) fasta scores; opt: 351, FT z-score: 343.1, E(): 8.3e-12, (33.3% identity in 201 aa FT overlap). Contains Pfam match to entry PF00877 NLPC_P60, FT NLP/P60 family at the C-terminus, a probable N-terminal FT signal sequence and two possible coiled coils. NOTE: highly FT similar to downstream gene, 6G10.08c, indicating a FT duplication event; fasta scores: opt: 1042, z-score: FT 1027.7, E(): 0, (49.9% identity in 339 aa overlap)" FT /db_xref="InterPro:IPR000064" FT /db_xref="UniProtKB/TrEMBL:Q9X7Z5" FT /protein_id="CAB39863.1" FT /translation="MASHRRPKQPSRTRVTVLTTAAAAAVVLSSQAANAAPSEKPSKDE FT VKAKVDKLYEEAEQATEKYNGAKEKQEKLQKEISTIQDNVARGQEELNELRDGLGSMAS FT AQYRSGGIDPSLQLFLSADPDNYLDKASTLDQLSGQQVEALKKIQVKQRDLAQQRSEAS FT EKLKDLSATRTDLGKKKKEVQGKLSSAQKLLNTLTAQEKAALQQDEQRSNRASERQVLT FT GGKSTPASGRAGAAFAAAQGKIGTPYVYGATGPSSFDCSGLTSWAYAQAGVGIPRTSQA FT QANYGTRISSSSQLQVGDLVFFFSDLHHVGLYAGNGQVLHAPRTGTNVRYESMSTIGGP FT FMFGVRV" FT misc_feature complement(195710..196033) FT /note="Pfam match to entry PF00877 NLPC_P60, NLP/P60 FT family, score 129.90, E-value 4.7e-35." FT CDS complement(196982..198325) FT /transl_table=11 FT /gene="SCO2137" FT /gene_synonym="SC6G10.10c" FT /product="hypothetical protein" FT /note="SC6G10.10c, unknown, len: 447aa; some similarity to FT TR:Q60218 (EMBL:L10330) TraN from plasmid RP4 of FT Escherichia coli (261 aa) fasta scores; opt: 176, z-score: FT 185.4, E(): 0.005, (29.5% identity in 224 aa overlap). FT Contains probable coiled coil region." FT /db_xref="InterPro:IPR010298" FT /db_xref="UniProtKB/TrEMBL:Q9X7Z6" FT /protein_id="CAB39864.1" FT /translation="MVETHGGGPGDGAAEVLDRPLPDGVRRRVVQIVSDGFGSLTLGEL FT PAQLRQYARFAPNRRIKFAGNAMAAAVETDPLFRQRIGEKFRDVQSELADALDAGSALP FT AADPLDVAAAAYVLRPHGWVKLVTAAGEEAQRADAERADEESRAELERLHEELSRAREH FT TRTETERLRGELDAAKRETESLHRKLRSALSDVKRGEAALRKVQAELDAVRAEGQTQVS FT AAESETRRLKARLGEAEAALEATRRAAREGRSVEDMRVRLLLDTLLDATQGLRRELALP FT PVSVRPAETVDAVEPGRMTPKDIANRALSENDPAILDQLLALPQAHLVVDGYNVTKTGY FT PQMPLEKQRLRLLGQLSQLAAQTGAEMTCVFDGAELVAPVLLAPPRGVRVLFSKPGVTA FT DELIRQLVRAEPPGRPVIVVSTDREVADGVARAGARPVASVVLLKRLS" FT CDS complement(198388..198627) FT /transl_table=11 FT /gene="SCO2138" FT /gene_synonym="SC6G10.11c" FT /product="hypothetical protein" FT /note="SC6G10.11c, len: 79aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X7Z7" FT /protein_id="CAB39865.1" FT /translation="MTVPLPTDTTRWRCTLCGNLTRFDVTRASKVVEYVHLDLAGEPTV FT EEREVLSETVESVRCRWCNAVDQVELVDRPGAAS" FT CDS 198785..199555 FT /transl_table=11 FT /gene="SCO2139" FT /gene_synonym="SC6G10.12" FT /product="putative integral membrane protein" FT /note="SC6G10.12, possible integral membrane protein, len: FT 256aa; similar to TR:O69868 (EMBL:AL023702) putative FT integral membrane protein from Streptomyces coelicolor (383 FT aa) fasta scores; opt: 569, z-score: 706.4, E(): 4.8e-32, FT (44.6% identity in 242 aa overlap). Contains possible FT hydrophobic membrane sapnning regions" FT /db_xref="GOA:Q9X7Z8" FT /db_xref="InterPro:IPR002610" FT /db_xref="UniProtKB/TrEMBL:Q9X7Z8" FT /protein_id="CAB39866.1" FT /translation="MIRNWSTAVRRTVTAVGGLVTARPSRRRTAPVTYTLITLCCLLFL FT ISPAAGLNPVYGTGEEVLAAQRAYFRRWGVIPAELFEDSPGSALTPATALFVHGSWVHL FT LGNMLFLYVFGAMTEERMGRLQFALFYLGCGYLALVGYAGANAHSQESLVGASGAISAV FT LGAFLFLFPRARVTSLLPFLFFLPLRFPAWVVLPFWVSLQWLAAGRAGDGPGVAYLAHL FT VGFGLGFAFAWVRFGRTTRVGGVPVAAPEGENQP" FT CDS 199552..199833 FT /transl_table=11 FT /gene="SCO2140" FT /gene_synonym="SC6G10.13" FT /product="putative transcriptional regulator" FT /note="SC6G10.13, possible transcriptional regulator, len: FT 93 aa; similar to many e.g. TR:O28868 (EMBL:AE001007) FT transcriptional regulatory protein, AsnC family from FT Archaeoglobus fulgidus (77 aa) fasta scores; opt: 148, FT z-score: 216.7, E(): 9.1e-05, (40.8% identity in 71 aa FT overlap) and SW: LRP_ECOLI Lrp, leucine responsive FT regulatory protein from Escherichia coli (163 aa) fasta FT scores; opt: 107, z-score: 157.6, E(): 0.18, (24.7% FT identity in 85 aa overlap)." FT /db_xref="GOA:Q9X7Z9" FT /db_xref="InterPro:IPR019887" FT /db_xref="UniProtKB/TrEMBL:Q9X7Z9" FT /protein_id="CAB39867.1" FT /translation="MISAIVLIKTSVDRIPEIAEQIAALESVSEVFSVTGTYDLIAMVR FT VSRHEDLADVIPGRISKIPGVEGTDTHVAFRTYSQHDLEAAFAIGLDN" FT CDS 199983..200306 FT /transl_table=11 FT /gene="SCO2141" FT /gene_synonym="SC6G10.14" FT /product="putative small secreted hydrophilic protein" FT /note="SC6G10.14, possible small secreted hydrophilic FT protein, len: 107aa; contains possible N-terminal signal FT sequence." FT /db_xref="UniProtKB/TrEMBL:Q9X800" FT /protein_id="CAB39868.1" FT /translation="MVFSRRMAALAAVVLIPLGIAATSFALTDSPQEPKVPAKVELESG FT SPTPAPTSSSPEPTPSDQVVTRPPVTDGPSDDDDDDDRGGRDAGESADSADDAAGDDGP FT GDG" FT CDS 200365..201729 FT /transl_table=11 FT /gene="SCO2142" FT /gene_synonym="SC6G10.15" FT /product="putative two component sensor kinase" FT /note="SC6G10.15, possible two component sensor kinase, FT len: 454 aa; similar to many e.g. SW:CUTS_STRCO CutS, two FT component sensor kinase involved in the regulation of FT copper metabolism in Streptomyces lividans 66 (414 aa) FT fasta scores; opt: 537, z-score: 580.3, E(): 5.1e-25, FT (34.8% identity in 328 aa overlap). Contains Pfam match to FT entry PF00512 signal, Signal carboxyl-terminal domain and FT Pfam match to entry PF00672 DUF5, Domain found in bacterial FT signal proteins. Also contains a possible membrane spanning FT hydrophobic region" FT /db_xref="GOA:Q9X801" FT /db_xref="HSSP:1BXD" FT /db_xref="InterPro:IPR003660" FT /db_xref="UniProtKB/TrEMBL:Q9X801" FT /protein_id="CAB39869.1" FT /translation="MAVALASVAATTRSILLRDTDQRINGLLAQEAGEFANFEEQGFDP FT ETGRPFTDPGRLLRVFLERQYADLDEELVGLVGEVGSRPTQIIQQREIPVGRPLHEDAD FT ARRRIYASPDSTGTLERPEGEIRWAKVTVARYGGEPAAAFVVAFHPGREQARADEVFRV FT LLAISGVALLMTTGIAWVVAGRILKPVRLVRTTAAQLTEQDLTRRIPVHGHDDVAALAE FT TFNAMLDRLERAFATQRRFVDDAGHELRTPITIVRGHLELMGDDPAEREETVRLVTDEL FT DRMSRIVEDLLLLAKAERPDFVTPEPVQLAELTADVFVKARTLGEREWVLDGVADREVH FT LDPQRITQAMVQLAQNAVQHTTAGQRVRIGSRADGWRIELYVADSGPGVQPQDAEVIFE FT RFRRGTARRGVRGTGAGLGLSIVRAIAEGHGGRVDLRTTAGGGATFVLTLEEARP" FT misc_feature 200854..201063 FT /note="Pfam match to entry PF00672 DUF5, Domain found in FT bacterial signal proteins, score 68.90, E-value 1.1e-16." FT misc_feature 201103..201714 FT /note="Pfam match to entry PF00512 signal, Signal FT carboxyl-terminal domain, score 172.70, E-value 6.2e-48." FT CDS 201726..202391 FT /transl_table=11 FT /gene="SCO2143" FT /gene_synonym="SC6G10.16" FT /product="putative two component system response regulator" FT /note="SC6G10.16, possible two component system response FT regulator, len: 221aa; similar to many eg. SW:IRLR_BURPS FT two component response regulator involved in heavy-metal FT resistance in Burkholderia pseudomallei (229 aa) fasta FT scores; opt: 635, z-score: 758.0, E(): 0, (50.0% identity FT in 220 aa overlap). Contains Pfam match to entry PF00072 FT response_reg, Response regulator receiver domain and Pfam FT match to entry PF00486 trans_reg_C, Transcriptional FT regulatory protein, C terminal." FT /db_xref="GOA:Q9X802" FT /db_xref="HSSP:1GXQ" FT /db_xref="InterPro:IPR005829" FT /db_xref="UniProtKB/TrEMBL:Q9X802" FT /protein_id="CAB39870.1" FT /translation="MNRILIVEDEERIASFVQKGLRANGFTTTAVADGDAAYEYALTGG FT FDLVVLDIGLPGRDGFTVLRELREARVTTPVIVLTARDSVRDTVAGLEGGADDWMTKPF FT RFEELLARVRLRLRTAARAPEVTVLRSGPLSLDLRTRRARSEGRTVDLTAREFVLLELF FT LRHPGQVLSREQILSHVWGYDFDPGSNIVDVYVRALRKKLGARQVETVRGMGYRLPTW" FT misc_feature 201729..202064 FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 124.10, E-value 2.5e-33." FT misc_feature 202167..202370 FT /note="Pfam match to entry PF00486 trans_reg_C, FT Transcriptional regulatory protein, C terminal, score FT 108.90, E-value 3.1e-31." FT misc_feature 202481..203878 FT /note="Pfam match to entry PF00939 Na_sulph_symp, FT Sodium:sulfate symporter transmembrane region, score FT -165.10, E-value 3.2e-06." FT CDS 202481..203890 FT /transl_table=11 FT /gene="SCO2144" FT /gene_synonym="SC6G10.17" FT /product="putative integral membrane transporter" FT /note="SC6G10.17, possible integral membrane transporter, FT len: 469aa; similar to many eg. SW:CITT_ECOLI CitR, citrate FT transporter from Escherichia coli (487 aa) fasta scores; FT opt: 257, z-score: 284.2, E(): 1.6e-08, (23.3% identity in FT 454 aa overlap). Contains Pfam match to entry PF00939 FT Na_sulph_symp, Sodium:sulfate symporter transmembrane FT region, score -165.10, E-value 3.2e-06 and several probable FT membrane spanning hydrophobic regions." FT /db_xref="GOA:Q9X803" FT /db_xref="InterPro:IPR001898" FT /db_xref="UniProtKB/TrEMBL:Q9X803" FT /protein_id="CAB39871.1" FT /translation="MNLRLAAALCAALSLCAVLAVPANFPALGGDARLTLAVFALATCA FT WIGTPIDDTYIALGAGLALTATGVISSDTLFGTLGEDTVWLLICAFVLAAAVARTGLAG FT RAAAFLVGGARTVRQLVHLTTAALVVTAFAMPATSGRAALALPVFLALAKVLADRKRLV FT VMLALLFPTVILLSAVATLIGAGAHLITVSVLWEATGDRIGFTQWLLLGLPLAVASSHL FT AAETVLLTTTRRADRAGPVRITAEEIQRHSESPVTGPWTQAEKRCALLLATVVALWCSE FT PLHRVSPAVVALIGAVVASSPALGTVRLKDALKTVPWSLLLFMAATMAMGVALADSGAA FT GWLVSGLPADVAPAVFLGVVVAVSTAAHLVLQSRSARSSVLVPLVIAAAVGAGVNPVAA FT ALASTAAAGFCHTLPASAKPVTLFSDVPGVPTYTPRDLLRLSAVLAPLTALLVLFFAAA FT VWPLLGVPVTR" FT CDS 203901..205199 FT /transl_table=11 FT /gene="SCO2145" FT /gene_synonym="SC6G10.18" FT /product="putative glycerate kinase" FT /note="SC6G10.18, unknown, len: 432aa; similar to many FT hypothetical proteins eg. SW:YXAA_BACSU hypothetical FT protein from Bacillus subtilis (382 aa) fasta scores; opt: FT 1005, z-score: 1049.9, E(): 0, (44.1% identity in 381 aa FT overlap). Note predicted C-terminal overlap with downstream FT CDS. Simialr also to SW:GRK_BACSU (EMBL:AB005554) Bacillus FT subtilis glycerate kinase (EC 2.7.1.31) GlxK or S14A, 382 FT aa; fasta scores: opt: 1005 Z-score:1015.2 E(): 6.5e-49; FT 44.094% identity in 381 aa overlap" FT /db_xref="GOA:Q9X804" FT /db_xref="InterPro:IPR018193" FT /db_xref="UniProtKB/TrEMBL:Q9X804" FT /protein_id="CAB39872.1" FT /translation="MSHPSPVLNRVVVAPSGFKESLSARAAADAIAAGVRRVLPDAEID FT RIPLVDGGEGTAVALASATGGRLVALAATGPVGDRVGTHFALLGTGDTAVVEMAAVAGL FT SLVPRALRDPGATTTYGVGELIRAALGTGVRRVLVGCGDSGTSDGGAGALQALGARLLD FT GDGFELGPGGRELNRLVRVDPSGLDARLKDTELLVACNPYNVLCGERGVARVFGPQKGA FT TPAQVEELSAGLENWARVLTRDLGVVGTDLRTGSGTGASGGLGAGLAAVGARLLPRFDV FT LLGHLDLDARLARADLVLTAEGALDHQTPRGKVPAEVARRAKLSGRPVLALAGTLGEGA FT HDVPGVDACHGIMPAPMALADALLRASELLTDATERALRMVLLGARLPAGPAQAAVPVT FT GAVPRDAGSPDAWSPDAVSPDAGSGTQRPSSVR" FT CDS complement(205076..206506) FT /transl_table=11 FT /gene="SCO2146" FT /gene_synonym="SC6G10.19c" FT /product="putative aminotransferase" FT /note="SC6G10.19c, possible aminotransferase, len: 476 aa; FT similar to SW:CSDB_ECOLI (EMBL:AE000263) Escherichia coli FT selenocysteine lyase (EC 4.4.1.16) CsdB, 406 aa; fasta FT scores: opt: 565 Z-score: 628.7 E(): 2.3e-27; 33.862% FT identity in 378 aa overlap. Contains Pfam match to entry FT PF00266 aminotran_5, Aminotransferases class-V. Note: FT C-terminus overlaps with downstream gene." FT /db_xref="GOA:Q9X805" FT /db_xref="HSSP:1C0N" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:Q9X805" FT /protein_id="CAB39873.1" FT /translation="MSVPTAVATPLPVLGRDVTVPLVTGGQVAYAALDYAASAPALQRV FT WDDVAAYAPYYGSVHRGAGYLSQLSTDLFENARGTVAGFLGCRDDDQVVFTRSTTDSLN FT LLAAALPAHCRVFVFETEHHASLLPWRAADVTYLDAPRTPAEAVETLERALAAREPYGP FT ALVCVTGASNVTGELWPVRELAAAAHAHGARIVLDAAQLAPHHPVSVRDLDVDWVAFSG FT HKLYAPFGSGVLAGRADWLREAEPYLAGGGASRSVSRRADGGVDVQWHDSAARHEAGSP FT NVIGVYAIASACKALTEAGFDTLVAREEYLIRKVREGLAEVPEVRVLSLFGDDAPRVGV FT LSFVVEGWNSSHFAAALSAEYGIGVRDGLFCAHPLVRTLLGSDPQTQGECGAPEAAPGE FT KSLNAIRVSFGAGTPDEHVERFVSAVRELVSDGARWNYRTEDGRCVPDPASGDTASGDH FT ASGDPASRGTAPVTGTAA" FT misc_feature complement(205244..206395) FT /note="Pfam match to entry PF00266 aminotran_5, FT Aminotransferases class-V, score -38.80, E-value 3.2e-05." FT CDS complement(206851..207915) FT /transl_table=11 FT /gene="SCO2147" FT /gene_synonym="SC6G10.20c" FT /gene_synonym="trpD1" FT /product="phosphoribosylanthranilate transferase" FT /note="SC6G10.20c, trpD1, phosphoribosylanthranilate FT transferase, len: 354 aa; previously sequenced therefore FT identical to TR:O68608 (EMBL:AF052077). Also similar to FT many others eg. SW:TRPD_MYCTU from Mycobacterium FT tuberculosis (370 aa) fasta scores; opt: 1091, z-score: FT 1205.4, E(): 0, (51.4% identity in 352 aa overlap). FT Contains Pfam match to entry PF00591 Glycos_transf_3, FT glycosyl transferase family." FT /db_xref="GOA:O68608" FT /db_xref="HSSP:1KHD" FT /db_xref="InterPro:IPR020072" FT /db_xref="UniProtKB/Swiss-Prot:O68608" FT /protein_id="CAB39874.1" FT /translation="MSAVTPAGGDTTADRSWPALLNGLLDGRDLSADDTAWALDVIMRG FT EATDVQIAGFAVGLRFKGETVEEISGLVRTMYEHANVIEVPGKTVDIVGTGGDGAKTVN FT ISTMSAIVLAGTGAKVVKHGNRAASSASGASDVLEKLGVNLELTPQRVAEVAEEAGITF FT CFAVKFHPALRHVATARGQLGIRTVFNFLGPLTNPARVKAQAVGVAHARMAPIVAGVFA FT ERGHSSLVFRGDDGLDELTTTSTSRVWVVRDGRVTEETFDPRDVGIELVPVEALRGADA FT SYNADVARRLLAGEKGPVRDAVLLNSAAALEALEPGEGALAERLRAGMDRAAEAIDSGA FT ARRVLERWVAVSHA" FT misc_feature complement(207415..207861) FT /note="Pfam match to entry PF00591 Glycos_transf_3, FT glycosyl transferase family, score 244.30, E-value FT 1.7e-69." FT CDS complement(208047..209684) FT /transl_table=11 FT /gene="SCO2148" FT /gene_synonym="SC6G10.21c" FT /gene_synonym="qcrB" FT /product="cytochrome B subunit" FT /note="SC6G10.21c, qcrB, cytochrome B subunit, len: 545 aa; FT almost identical to one previously sequenced in FT Streptomyces lividans TR:G4154324 (EMBL:AF107888) (549 aa) FT fasta scores: opt: 3501, z-score: 3791.6, E(): 0, (95.5% FT identity in 550 aa overlap). Also similar to SW:QCRB_BACST FT cytochrome B subunit from Bacillus stearothermophilus (224 FT aa) fasta scores; opt: 409, z-score: 451.8, E(): 7.2e-18, FT (30.0% identity in 240 aa overlap). Contains Pfam match to FT entry PF00033 cytochrome_b_N, Cytochrome FT b(N-terminal)/b6/petB. Also contains several probable FT membrane spanning hydrophobic regions." FT /db_xref="GOA:Q9X806" FT /db_xref="InterPro:IPR005797" FT /db_xref="UniProtKB/Swiss-Prot:Q9X806" FT /protein_id="CAB39875.1" FT /translation="MSTAANEPSRSRGKAPAGERVADWADGRLGIYSLAKANMRKIFPD FT HWSFMLGEVCLYSFIIIILTGVYLTLFFHPSMAEVEYHGSYVPLQGQMMSEAYASTLDI FT SFDVRGGLLIRQIHHWAALIFLAGMFVHMMRVFFTGAFRKPREVNWLFGFLLLVLGMFT FT GFTGYSLPDDLLSGTGIRFMEGAILSVPIVGTYISFFLFGGEFPGHDFVSRFYSIHILL FT LPGIMLGLLVGHLILVFYHKHTQFAGPGKTNKNVVGMPLLPVYTAKAGGFFFLVFGVIS FT VVSAIATINPIWAIGPYRPDQVSTGAQPDWYMGFSEGLIRVMPGWEINAWGHTLVLGVF FT VPLLIFPLVLAAIAVYPFIESWVTGDKREHHILDRPRNAPTRTAFGVAWLTVYFVLLIG FT GGNDLWATHFHLSINAITWFVRIAFFVGPVVAFIATKRICLGLQRRDKDKVLHGRESGI FT IKRLPHGEFIEVHEPLSQEQLHTLTAHEQYQPAEIGPTVDENGVERKVSGTQKLRAKLS FT ESYYGEESQIPKPTVEEYKEITSGHGHH" FT misc_feature complement(208959..209630) FT /note="Pfam match to entry PF00033 cytochrome_b_N, FT Cytochrome b(N-terminal)/b6/petB, score 62.10, E-value FT 1.2e-14." FT CDS complement(209681..210742) FT /transl_table=11 FT /gene="SCO2149" FT /gene_synonym="SC6G10.22c" FT /gene_synonym="qcrA" FT /product="Rieske iron-sulfur protein" FT /note="SC6G10.22c, qcrA, Rieske iron-sulfur protein, len: FT 353 aa; identical over the partial sequence of QcrA, Rieske FT iron-sulfur protein from Streptomyces lividans (170 aa) FT fasta scores; opt: 1174, z-score: 1332.,1 E(): 0, (100.0% FT identity in 169 aa overlap). SW:UCRI_BRAJA ubiquinol FT cytochrome C reductase iron-sulphur subunit (176 aa) fasta FT scores; opt: 156, z-score: 186.0, E(): 0.0047, (33.3% FT identity in 84 aa overlap). Contains Prosite match to FT PS00200 Rieske iron-sulfur protein signature 2 and possible FT hydrophobic membrane spanning regions" FT /db_xref="GOA:Q9X807" FT /db_xref="InterPro:IPR017941" FT /db_xref="UniProtKB/Swiss-Prot:Q9X807" FT /protein_id="CAB39876.1" FT /translation="MSSQDIPEENLPAEQDRPHGAAARPADETNPFADPGLPPHEPRVQ FT DVDERAAKRSERTVALLFTLSMLATIAFIAAFVAIDVDKSVYIFPLGHISALNFALGMT FT LGVALFAIGAGAVHWARTLMSDEEVADERHPIEASPEVRAKVHADFKQGAKESVIGRRK FT LIRNTMLGALTLVPLSGVVLLRDLGPLPGTKLRHTLWSKGKLLVNMNTNEPLRPSDVAV FT GSLTFAMPEGLEEHDEDFQNEIAKAALMIIRLEPDSIKDKRELEWSHEGIVAYSKICTH FT VGCPISLYEQQTHHALCPCHQSTFDLADGARVIFGPAGHALPQLRIGVNDEGYLEALGD FT FEEPVGPAYWERG" FT misc_feature complement(209834..209851) FT /note="PS00200 Rieske iron-sulfur protein signature 2." FT CDS complement(210739..211548) FT /transl_table=11 FT /gene="SCO2150" FT /gene_synonym="SC6G10.23c" FT /gene_synonym="qcrC" FT /product="cytochrome C heme-binding subunit" FT /note="SC6G10.23c, qcrC, cytochrome C heme-binding subunit, FT len: aa; similar to many eg. TR:O69583 (EMBL:AL022602) FT proposed QcrC protein from Mycobacterium leprae (164 aa) FT fasta scores; opt: 368, z-score: 374.3, E(): 1.5e-13, FT (45.4% identity in 141 aa overlap). Contains two Pfam FT matches to entry PF00034 cytochrome_c, Cytochrome c and two FT Prosite matches to PS00190 Cytochrome c family heme-binding FT site signature. Also contains possible membrane spanning FT hydrophobic regions." FT /db_xref="GOA:Q9X808" FT /db_xref="HSSP:1CTZ" FT /db_xref="InterPro:IPR009056" FT /db_xref="UniProtKB/TrEMBL:Q9X808" FT /protein_id="CAB39877.1" FT /translation="MKKLSARRRHPLAALVVLLLALACTGGLYAAFAPASKAQADESAQ FT SLAIDEGKKLYAVGCASCHGTGGQGTSDGPSLVGVGAAAVDFQVGTGRMPAQQPGAQVP FT KKKVIYSQAEIDQLAAYIASLGAGPAIPSEEKYGPEGADIAKGGELFRTNCAQCHNFTG FT KGGALTHGKYAPSLEGVDPKHIYEAMQTGPQNMPSFPDTTLSEQNKKDIIAYLDAVNGD FT DTESPGGLSLGGLGPVSEGLFAWVFGLGALIAVAVWVAARTAKAKKS" FT misc_feature complement(210889..211125) FT /note="Pfam match to entry PF00034 cytochrome_c, Cytochrome FT c, score 40.20, E-value 4.6e-08." FT misc_feature complement(211069..211086) FT /note="PS00190 Cytochrome c family heme-binding site FT signature." FT misc_feature complement(211171..211404) FT /note="Pfam match to entry PF00034 cytochrome_c, Cytochrome FT c, score 28.60, E-value 0.00014." FT misc_feature complement(211354..211371) FT /note="PS00190 Cytochrome c family heme-binding site FT signature." FT CDS complement(211623..212243) FT /transl_table=11 FT /gene="SCO2151" FT /gene_synonym="SC6G10.24c" FT /gene_synonym="cox3" FT /product="cytochrome c oxidase subunit III" FT /note="SC6G10.24c, cox3, cytochrome c oxidase subunit III, FT len: 206aa; similar to many eg. SW:COX3_BACP3 caaC, FT cytochrome c oxidase subunit III from Bacillus PS3 (207 aa) FT fasta scores; opt: 397, z-score: 511.9, E(): 3.3e-21, FT (35.9% identity in 181 aa overlap). Contains Pfam match to FT entry PF00510 COX3, Cytochrome c oxidase subunit III." FT /db_xref="GOA:Q9X809" FT /db_xref="InterPro:IPR013833" FT /db_xref="UniProtKB/Swiss-Prot:Q9X809" FT /protein_id="CAB39878.1" FT /translation="MSVVATATTVETGHAHPSVNRPNLTSVGTIIWLSSELMFFAALFA FT MYFTLRSVTGPDFWSEKADALNIPFSATNTTILVLSSLTCQLGVFAAERGDVKKLRMWF FT IVTFVMGAIFIGGQVFEYTELVKHEGISLSSDPYGSAFYLTTGFHGLHVTGGLIAFLLV FT LGRTYAARRFTHEQATAAIVVSYYWHFVDVVWIGLFATIYLIK" FT misc_feature complement(211632..212243) FT /note="Pfam match to entry PF00510 COX3, Cytochrome c FT oxidase subunit III, score -112.10, E-value 8.9e-07." FT CDS 212453..212854 FT /transl_table=11 FT /gene="SCO2152" FT /gene_synonym="SC6G10.25" FT /product="putative response regulator" FT /note="SC6G10.25, possible response regulator, len: 133aa; FT similar to TR:P95183 (EMBL:Z83867) hypothetical protein FT from Mycobacterium tuberculosis (133 aa) fasta scores; opt: FT 474, z-score: 602.8, E(): 2.8e-26, (54.2% identity in 120 FT aa overlap) and TR:E1358527 (EMBL:AJ131213) response FT regulator from Streptomyces coelicolor (234 aa) fasta FT scores; opt: 122, z-score: 162.8, E(): 0.091, (28.5% FT identity in 130 aa overlap)" FT /db_xref="GOA:Q9X810" FT /db_xref="InterPro:IPR001789" FT /db_xref="UniProtKB/TrEMBL:Q9X810" FT /protein_id="CAB39879.1" FT /translation="MQATATVLVYSDDSNTREQVRLATGRRPAPDVPVVEFVECATPAA FT VLKELDRGGIDVCVLDGEAVPMGGMGMCRQIKDEVFQCPPVLLLIARPQDAWLATWSRA FT EAAVTLPVEPVEFASALAALLREKRLQGV" FT CDS complement(212942..214216) FT /transl_table=11 FT /gene="SCO2153" FT /gene_synonym="SC6G10.26c" FT /product="putative secreted protein" FT /note="SC6G10.26c, possible secreted protein, len: 424aa; FT similar to many of undefined function eg. TR:O53223 FT (EMBL:AL021185) hypothetical protein from Mycobacterium FT tuberculosis (408 aa) fasta scores; opt: 867, z-score: FT 941.5, E(): 0, (35.2% identity in 403 aa overlap). Contains FT Prosite matches to PS00013 Prokaryotic membrane lipoprotein FT lipid attachment site and PS00213 Lipocalin signature. Also FT contains possible N-terminal signal sequence." FT /db_xref="InterPro:IPR005490" FT /db_xref="UniProtKB/TrEMBL:Q9X811" FT /protein_id="CAB39880.1" FT /translation="MSNTVHFQARGRTVVGCTLLVIALGASVTACLGDDDNPLSATPYD FT AAGQISFNGPTEAGKKADPDKPLEVVAEGADGRITDVTAMDAAGRHVAGELSADGARWH FT STSPLAANASYTVRVSTEDGDGAPGRKVLTFETGKPGAKKTLDVAFGPKAGAYGVGQPI FT TAELSQPVRDPAQRAIVERALKVDSTPAVRGAWYWVDDKKLHYRPEEYWPAHATVKVHS FT TLDGIKIGDRMWGGKAKPLKITTDDRVVAVTDAAAHTLTVYQDGEAIREIPVTTGKPGF FT ETRNGVKVVLGKESFVRMRSSTVGIAEGSSEAYDLPVYWATRVTWSGEYVHAAPWSVGS FT QGIANVSHGCVGMSTDSAEWFFNTVQEGDLVEVVNSGGETMEPFGNGFGDWNMDWTKWR FT TGSALTGGTGASNNQDTARLRPTAV" FT misc_feature complement(213620..213658) FT /note="PS00213 Lipocalin signature." FT misc_feature complement(214124..214156) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site." FT stem_loop 214289..214334 FT /note="Imperfect inverted repeat, 20/21 ( 95%) matches, FT with 4 base loop." FT CDS complement(214363..214761) FT /transl_table=11 FT /gene="SCO2154" FT /gene_synonym="SC6G10.27c" FT /product="putative integral membrane protein" FT /note="SC6G10.27c, possible integral membrane protein, len: FT 132aa; similar to proteins of undefined function eg. FT SW:Y00A_MYCTU hypothetical protein from Mycobacterium FT tuberculosis (139 aa) fasta scores; opt: 317, z-score: FT 403.3, E(): 3.7e-15, (38.3% identity in 133 aa overlap)." FT /db_xref="GOA:Q9X812" FT /db_xref="UniProtKB/Swiss-Prot:Q9X812" FT /protein_id="CAB39881.1" FT /translation="MKIQGKMFIWLSVFILAVAVVYGYWSKEPAGTTALFLAFGLAIMI FT GFYLAFTARRVDAGAQDDMEADVADEAGEVGFFSPHSWQPLSLAVGGALAFLGIAVGWW FT VMYFSAPILMVGLFGWVFEYYRGENRTQ" FT CDS complement(214758..216494) FT /transl_table=11 FT /gene="SCO2155" FT /gene_synonym="SC6G10.28c" FT /gene_synonym="cox1" FT /product="putative cytochrome c oxidase subunit I" FT /note="SC6G10.28c, cox1, cytochrome c oxidase subunit I, FT len: 578aa; similar to many eg. SW:COX1_BACFI cytochrome c FT oxidase polypeptide I from Bacillus firmus (624 aa) fasta FT scores; opt: 1835, z-score: 2056.2, E(): 0, (49.5% identity FT in 527 aa overlap). Contains Pfam match to entry PF00115 FT COX1, Cytochrome C and Quinol oxidase polypeptide I and FT Prosite matches to PS00152 ATP synthase alpha and beta FT subunits signature and PS00077 Heme-copper oxidase FT catalytic subunit, copper B binding region signature. Also FT contains several probable membrane spanning hydrophobic FT regions." FT /db_xref="GOA:Q9X813" FT /db_xref="HSSP:1FFT" FT /db_xref="InterPro:IPR014241" FT /db_xref="UniProtKB/Swiss-Prot:Q9X813" FT /protein_id="CAB39882.1" FT /translation="MSILNEPQGASAAEDSYENELPVRRKQPGNVVIKWLTTTDHKTIG FT TMYLVTSFAFFVIGGVMALFMRAELARPGLQIMSNEQFNQAFTMHGTIMLLMFATPLFA FT GFANWIMPLQIGAPDVAFPRLNMFAYWLYLFGSTIAVGGFLTPQGAADFGWFAYSPLSD FT AVHSPGIGGDLWIMGLAFSGFGTILGSVNFITTIICMRAPGMTMFRMPIFTWNVLLTGV FT LVLLAFPVLAAALFALEADRKFGAHIFDSSNGGALLWQHLFWFFGHPEVYIIALPFFGI FT VSEIIPVFSRKPIFGYMGLIGATIAIAGLSVTVWAHHMYVTGGVLLPFFSFMTFLIAVP FT TGVKFFNWIGTMWKGSLSFETPMLWSTGFLITFLFGGLTGVILASPPLDFHVSDSYFVV FT AHFHYVVFGTVVFAMFAGFHFWWPKFTGKMLDERLGKITFWTLFVGFHGTFLVQHWLGA FT EGMPRRYADYLAADGFTALNTISTISSFLLGMSILPFFYNIWKTAKYGKKIEVDDPWGY FT GRSLEWATSCPPPRHNFLTLPRIRSESPAFDLHHPEISAIDQLENVGHGEKALAGGKEA FT GK" FT misc_feature complement(215031..216395) FT /note="Pfam match to entry PF00115 COX1, Cytochrome C and FT Quinol oxidase polypeptide I, score 747.60, E-value FT 5.1e-221." FT misc_feature complement(215310..215339) FT /note="PS00152 ATP synthase alpha and beta subunits FT signature." FT misc_feature complement(215541..215705) FT /note="PS00077 Heme-copper oxidase catalytic subunit, FT copper B binding region signature." FT CDS complement(216491..217450) FT /transl_table=11 FT /gene="SCO2156" FT /gene_synonym="SC6G10.29c" FT /gene_synonym="cox" FT /product="putative cytochrome c oxidase subunit II" FT /note="SC6G10.29c, cox2, cytochrome c oxidase subunit II, FT len: 319aa; similar to many eg. SW:COX2_MYCTU cox2, FT PUTATIVE cytochrome c oxidase subunit II from Mycobacterium FT tuberculosis (363 aa) fasta scores; opt: 417, z-score: FT 477.1, E(): 2.8e-19, (35.4% identity in 308 aa overlap). FT Contains two Pfam match to entry PF00116 COX2, Cytochrome C FT oxidase subunit II and Prosite match to PS00078 CO II and FT nitrous oxide reductase dinuclear copper centers FT signature." FT /db_xref="GOA:Q9X814" FT /db_xref="InterPro:IPR002429" FT /db_xref="UniProtKB/Swiss-Prot:Q9X814" FT /protein_id="CAB39883.1" FT /translation="MSPNGSDRSPRRPMRRKLLQALTAGLVLATATGCTYEDFPRLGMP FT TPTTEEAPRILSLWQGSWAAALATGVLVWGLILWSVFFHRRSRTKVEVPPQTRYNLPIE FT ALYTMVPLVIVSVLFYFTARDESDLMSLNKKPDLTVNVVGFQWSWCFNHIEDVPGSTGD FT AKTSKELAGIPDRFIEDFPANAGGVYDCGTPGTENPQTGNPGPTLWLPKGKTVRFVLTS FT RDVIHSFWVVPFLMKQDVIPGHTNAFEVTPNKEGTFLGKCAELCGVDHSRMLFNVKVVS FT PERYEQHLQDLAKKGQTGYVPAGIAQTSHEKNRETNNL" FT misc_feature complement(216587..216823) FT /note="Pfam match to entry PF00116 COX2, Cytochrome C FT oxidase subunit II, score 62.60, E-value 3e-16." FT misc_feature complement(216632..216778) FT /note="PS00078 CO II and nitrous oxide reductase dinuclear FT copper centers signature." FT misc_feature complement(217004..217069) FT /note="Pfam match to entry PF00116 COX2, Cytochrome C FT oxidase subunit II, score 3.70, E-value 6.6." FT CDS 217777..219159 FT /transl_table=11 FT /gene="SCO2157" FT /gene_synonym="SC6G10.30" FT /product="putative aminotransferase" FT /note="SC6G10.30, probable aminotransferase, len: 460 aa; FT similar to many NifS-like proteins e.g. SW:NIFS_RHOSH NifS FT protein from Rhodobacter sphaeroides (387 aa) fasta scores; FT opt: 702, z-score: 760.5, E(): 0, (37.4% identity in 390 aa FT overlap). Contains Pfam matches to entry PF00266 FT aminotran_5, Aminotransferases class-V and entry PF01206 FT UPF0033, Uncharacterized protein family UPF0033." FT /db_xref="GOA:Q9X815" FT /db_xref="HSSP:1DCJ" FT /db_xref="InterPro:IPR001455" FT /db_xref="UniProtKB/TrEMBL:Q9X815" FT /protein_id="CAB39884.1" FT /translation="MAYFDAASAAPLHPVARQALLASLDEGWADPARLYREGRRARLLL FT DAAREATAECVGCRPDELVFTPSGTRAVHSGVAGALAGRRRVGRHLIVSAVEHSSVLHA FT AEAHEAGGGSLTQVGVDRAGAVDPAAYAAALGEDTALACLQSANHEVGTEQPVARVAEA FT CRAAGVPLLVDAAQSLGWGRVEGDWSLLTGSAHKWGGPSGVGLLAVRKGVRFAPQGPED FT ERESGRAPGFENLPAIVAAAASLRAVRAEATAEAARLRELTERIRSRVPELVPDVEVVG FT DPSRRLPGIVTFSCLYVDGETLLHELDRAGFSVSSGSSCTSSTLTPSHVLRAMGVLSEG FT NVRVSLPPGTAAEDVERFLEVLPGTVAAVREKLGAPAATENVRAAGPGLVVDALSRRCP FT IPVIELAKVIGDVPVGATVRVLSDDEAARLDIPAWCEMRGQEYVGEEPVEGGTAYLVRR FT TR" FT misc_feature 217810..218850 FT /note="Pfam match to entry PF00266 aminotran_5, FT Aminotransferases class-V, score 172.80, E-value 5.8e-48." FT misc_feature 218929..219150 FT /note="Pfam match to entry PF01206 UPF0033, Uncharacterized FT protein family UPF0033, score 24.30, E-value 5.3e-05." FT CDS complement(219282..220298) FT /transl_table=11 FT /gene="SCO2158" FT /gene_synonym="SC6G10.31c" FT /product="putative kinase" FT /note="SC6G10.31c, probable kinase, len: 338 aa; similar to FT many e.g. SW:RBSK_BACSU ribokinase from Bacillus subtilis FT (293 aa) fasta scores; opt: 222, z-score: 264.5, E(): FT 2e-07, (26.6% identity in 252 aa overlap). Contains Prosite FT matches to PS00583 pfkB family of carbohydrate kinases FT signature 1 and PS00485 Adenosine and AMP deaminase FT signature." FT /db_xref="GOA:Q9X816" FT /db_xref="HSSP:1LII" FT /db_xref="InterPro:IPR006650" FT /db_xref="UniProtKB/TrEMBL:Q9X816" FT /protein_id="CAB39885.1" FT /translation="MNRQPASPQERVHAVRIAVTGSIATDHLMTFPGRFSDQLVADQLH FT TVSLSFLVDQLDVRRGGVAANIAFGMGQLGTRPVLVGAAGSDFDEYRAWLDRHGVDTDS FT VRISETLHTARFVCTTDADHNQIGSFYTGAMSEARLIELKTVADRVGGLDLVSIGADDP FT EAMLRHTEECRARSIPFAADFSQQIARMNGDEIRILLDGATYLFSNEYEKGLIETKTGW FT SDAEILDRVGHRVTTLGARGVRIERAGGETIEVGVPDEERKADPTGVGDAFRAGFLSGL FT AWGVSLERAAQVGCMLATLVIETVGTQEYQLRRGHFMERFTKAYGDEAAGEVQAHLG" FT misc_feature complement(219810..219830) FT /note="PS00485 Adenosine and AMP deaminase signature." FT misc_feature complement(220044..220118) FT /note="PS00583 pfkB family of carbohydrate kinases FT signature 1." FT CDS 220389..220598 FT /transl_table=11 FT /gene="SCO2159" FT /gene_synonym="SC6G10.32" FT /product="hypothetical protein" FT /note="SC6G10.32, unknown, len: 69aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X817" FT /protein_id="CAB39886.1" FT /translation="MTNPRTVDPAPADLDGDLASLRGDCARMTPRWSAPADASARPVPL FT ALIHGVRVPPASARLLDAMSDYGD" FT CDS 220715..222265 FT /transl_table=11 FT /gene="SCO2160" FT /gene_synonym="SC6G10.33" FT /product="putative large membrane protein" FT /note="SC6G10.33, possible large membrane protein, len: 516 FT aa; contains possible hydrophobic membrane spanning region FT near the N-terminal domain" FT /db_xref="UniProtKB/TrEMBL:Q9X818" FT /protein_id="CAB39887.1" FT /translation="MNTERPDNDDAADEAGGGRPARRRPRAVAVASVAAAVLLMGGGGA FT YLATSATGDDADGGTASGAPGDDTPPPLPLDDHGASSPEGGPNGIAPGEPDPHGVTYRA FT DGPLPEGPGSAPVYRAKGDVTEAEVARLAEALGVEGAPRTQGEAWKAGNAKDGSGPLLT FT VSRRAPGTWTFHRYAPGTDNCKKGPVCKAPPADGNPVGEAAAKKAAAPVLKALGQDDAK FT LDASQVMGAGRAVNAEPEVGGLPTYGWTTGIVVGAQGEVIGGSGRMKAPVKGDAYPVLN FT AEETLALLNAPGAGSGADAGGVGGVGGIGGCASPVPHQDGADTPCGPPTGAPERPGAGK FT RQTATVEDAVFGLAAHPVRGQQTLVPSWLFQVRAPGARDAVTVTYPAVEPRFLTTAAPA FT TPPTSPSAPDEPTAGPGEPRDVRVSGYTAADGELTVHFTGGVCSDYDAKAKESGGKVTV FT TVTETPHPDQVCILIAKEYERTVPLDVPLGDRTVVGSDGKDVPVHKPGARLPAPSGAG" FT stem_loop 222286..222328 FT /note="Perfect inverted repeat, 19/19 (100%) matches, 5 FT base loop." FT CDS complement(222368..222724) FT /transl_table=11 FT /gene="SCO2161" FT /gene_synonym="SC6G10.34c" FT /product="conserved hypothetical protein" FT /note="SC6G10.34c, conserved hypothetical protein, len: 118 FT aa; similar to many e.g. SW:YM04_MYCTU (EMBL:Z70283) FT protein RV2204c from Mycobacterium tuberculosis (118 aa) FT fasta scores; opt: 625, z-score: 766.6, E(): 0, (74.6% FT identity in 118 aa overlap). Contains PS01152 Hypothetical FT hesB/yadR/yfhF family signature" FT /db_xref="GOA:Q9X819" FT /db_xref="HSSP:1NWB" FT /db_xref="InterPro:IPR017870" FT /db_xref="UniProtKB/TrEMBL:Q9X819" FT /protein_id="CAB39888.1" FT /translation="MSVSDETTTVTDGIILTDAAAAKVKALLDQEGRDDLALRVAVQPG FT GCSGLRYQLFFDERSLDGDVVKDFGGVKVTTDRMSAPYLGGATVDFVDTIEKQGFTIDN FT PNATGSCACGDSFS" FT misc_feature complement(222374..222427) FT /note="PS01152 Hypothetical hesB/yadR/yfhF family FT signature." FT CDS 223064..224248 FT /transl_table=11 FT /gene="St6G10A.01" FT /gene_synonym="SCO2162" FT /gene_synonym="SC6G10.35" FT /product="putative quinolinate synthetase (fragment)" FT /note="SC6G10A.01, probable quinolinate synthetase FT (fragment), len: >279 aa; similar to C-terminal part of FT SW:NADA_ECOLI (EMBL:X12713) Escherichia coli quinolinate FT synthetase A NadA, 347 aa; fasta scores: opt: 216 z-score: FT 269.3 E(): 1.5e-07; 26.5% identity in 283 aa overlap. FT Contains Pfam match to entry PF02445 NadA" FT /note="SC6G10.35, possible quinolinate synthetase FT (fragment), len: >154 aa; similar to many e.g. TR:O32063 FT (EMBL:Z99118) putative NadA, quinolinate synthetase from FT Bacillus subtilis (368 aa) fasta scores; opt: 442, z-score: FT 533.6, E(): 2e-22, (60.7% identity in 107 aa overlap) and FT SW:NADA_ECOLI NadA, quinolinate synthetase from Escherichia FT coli (347 aa) fasta scores; opt: 165, z-score: 204.7, E(): FT 0.00043, (37.0% identity in 100 aa overlap)." FT /db_xref="GOA:Q9F364" FT /db_xref="InterPro:IPR003473" FT /db_xref="UniProtKB/Swiss-Prot:Q9F364" FT /protein_id="CAD55295.1" FT /translation="MTTAQTQELDVQPTPLALLLLGREADPRSERGVECPGDLPSPSDP FT DLVARARAAKEKLGDKVFVLGHHYQRDEVIQFADVTGDSFKLARDAAARPEAEYIVFCG FT VHFMAESADILTSNDQKVVLPDLAAGCSMADMATAEQVAECWDVLTEAGIAEQVVPVSY FT MNSSADIKAFTGKHGGTICTSSNAERALNWAFEQGEKVLFLPDQHLGRNTAVRDLGMSL FT EDCVVYNPHRPNGGLTAKELRDANMILWRGHCSVHGRFSLDSVNDVRERIPGVNVLVHP FT ECKHEVVAAADYVGSTEYIIKALEAAPAGSKWAIGTELNLVRRLANRFAAEDKEIVFLD FT KTVCFCSTMNRIDLPHLVWTLESLAEGTLVNRIEVDQETEAFAKLALERMLALP" FT misc_feature 223412..224242 FT /note="Pfam match to entry PF02445 NadA, , score 218.90, FT E-value 7.7e-62" FT CDS complement(224327..227452) FT /transl_table=11 FT /gene="SCO2164" FT /gene_synonym="SC5F7.37c" FT /gene_synonym="St6G10A.02c" FT /product="putative integral membrane efflux protein" FT /note="SC5F7.37c, possible integral membrane efflux FT protein, len: >822aa; similar to SW:ACRD_ECOLI acriflavin FT resistance efflux protein from Escherichia coli (1037 aa) FT fasta scores; opt: 628, z-score: 629.0, E(): 1.1e-27, FT (22.9% identity in 853 aa overlap). Also similar to FT TR:O31501 (EMBL:Z99107) hypothetical protein from Bacillus FT subtilis (1065 aa) fasta scores; opt: 968, z-score: 969.5, FT E(): 0, (29.4% identity in 874 aa overlap). Contains Pfam FT match to entry PF00873 ACR_tran, AcrB/AcrD/AcrF family. FT Also contains possible membrane spanning hydrophobic FT regions." FT /note="SC6G10A.02c, possible integral membrane efflux FT protein (fragment), len: >253 aa; similar to C-terminal FT region of SW:CZCA_ALCSP (EMBL:D67044) Alcaligenes sp. FT cation efflux system protein CzcA, 1063 aa; fasta scores: FT opt: 474 z-score: 507.7 E(): 7.7e-21; 34.6% identity in 246 FT aa overlap. Contains Pfam match to entry PF00873 ACR_tran, FT AcrB/AcrD/AcrF family. Also contains possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q8CK05" FT /db_xref="HSSP:1IWG" FT /db_xref="InterPro:IPR001036" FT /db_xref="UniProtKB/TrEMBL:Q8CK05" FT /protein_id="CAD55296.1" FT /translation="MSWLSRFSLAQRALIGLVSIVALVFGAIAIPQLKQQLLPTIELPM FT VSVLAPYQGASPDVVEKQVVEPIEDSLEAVDGISGVTATASEGNAVIMASFDYGPDNQQ FT LVADVQQAVNRARAQLPDDVDPQVISGSTDDIPTVVLAVTSDKDQQALADQLDKTVVSE FT LKDIDGVAQVVVDGVRDVQVTVTPDPAKLAAAKVSPQALAQSLQAGGATVPAGSFDEAG FT ANRTVQVGGGFTSVKQIQDLMVTGEGVDEPVRLGDVATVKEEEAKADSLTRTNGKPSLA FT VAVTMDHDGSAVSISNAVEDKLPDLREQLGSGATLTVVSDQGPAVSKAISGLTTEGGLG FT LLFAVLVILVFLASIRSTLVTAVSIPLSVVLALIVLWTRDLSLNMLTLGALTIAIGRVV FT DDSIVVLENIKRHLGYGEERKDAILNAVREVAGAVTSSTLTTVAVFLPIGLVGGMVGEL FT FGSFSLTVTAALLASLLVSLTVVPVLSYWFLRPPKGTPQDAAEARRLAEEKEARSRLQR FT FYVPVLRFATRRRLTSVAIAIVVLVGTFGMAPLLKTNFFDQGEQEVLSVKQELKPGTSL FT GATDEQVKKVEKLLGDTEGVKDYQVTIGSSGFMAAFGGGTDTNQASYQLMLEDSANADD FT VQDHIEDGLAKLGDGIGTTTLAAGDGFGSQDLSVVVKAADAQVLRDAAEQVRKTVAGLD FT DVTDVTSDLAQSVPRISVKANAKAADAGFTDQTLGAAVAQAVRGTPAAKATLNDTERDV FT VIKSAQPARTMAELKALNLGAAKLGDIATVQLVDGPVSMTRIDGQRAATITAKPTGDNT FT GAVGADLQSKINGLDLPAGATAEIGGVTADQDDAFVNLGLAMLAAIAIVFMLLVGTFRS FT LAQPLILLVSIPFAATGAIGLLIATGTPMGVPAMIGMLMLIGIVVTNAIVLIDLINQYR FT KQGYGVVEAVVEGGRHRLRPILMTALATIFALLPMALGVTGEGGFIAQPLAVVVIGGLI FT TSTLLTLLLVPTLYAMLELRKERRAKKRAAKKGGGDVPPQPAASDEPEPAQV" FT misc_feature complement(224432..225088) FT /note="Pfam match to entry PF00873 ACR_tran, AcrB/AcrD/AcrF FT family, score 236.50, E-value 3.9e-67" FT misc_feature complement(225635..227443) FT /note="Pfam match to entry PF00873 ACR_tran, AcrB/AcrD/AcrF FT family, score 458.00, E-value 7.7e-134." FT CDS complement(227632..228315) FT /transl_table=11 FT /gene="SCO2165" FT /gene_synonym="SC5F7.36c" FT /product="putative two component system response regulator" FT /note="SC5F7.36c, probable two component system response FT regulator, len: 227 aa; similar to many others from FT Streptomyces coelicolor egs. TR:O69816 (EMBL:AL023496) FT proposed two component regulator (224 aa) fasta scores; FT opt: 753, z-score: 882.2, E(): 0, (57.4% identity in 223 aa FT overlap) and TR:Q53894 (EMBL:U51332) AbsA2 two component FT response regulator of antibiotic synthesis (222 aa) fasta FT scores; opt: 564, z-score: 663.8, E(): 1.2e-29, (44.6% FT identity in 222 aa overlap). Contains Prosite match to FT PS00622 Bacterial regulatory proteins, luxR family FT signature and Pfam matches to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family and to entry PF00072 FT response_reg, Response regulator receiver domain.Contains FT helix-turn-helix motif (+2.94 SD) 178-199aa." FT /db_xref="GOA:Q9S2S1" FT /db_xref="HSSP:1QMP" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9S2S1" FT /protein_id="CAB51249.1" FT /translation="MTIRVLLADDQALLRSAFRVLVDSEPDMEVVGEASDGAEAARLAA FT EQRADVVLMDIRMPGTDGLAATRMISADPSLAHVRVVILTTFEVDDYVVQSLRAGASGF FT LGKGSEPEELLSAIRVAAGGEALLSPTATKGLIARFLAQQDTTDEDRDPARAERLESLT FT VREREVLVQVAGGHSNDEIAERLEVSPLTVKTHVNRAMAKLGARDRAQLVVIAYESGLV FT RPRVE" FT misc_feature complement(227644..227841) FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 80.90, E-value FT 2.7e-20." FT misc_feature complement(227707..227790) FT /note="PS00622 Bacterial regulatory proteins, luxR family FT signature." FT misc_feature complement(227962..228309) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 131.40, E-value 1.6e-35." FT CDS complement(228312..229562) FT /transl_table=11 FT /gene="SCO2166" FT /gene_synonym="SC5F7.35c" FT /product="putative two component sensor kinase" FT /note="SC5F7.35c, probable two component sensor kinase, FT len: 416 aa; similar to many others from Streptomyces FT coelicolor egs. TR:CAB40930 (EMBL:AL049630) putative two FT component sensor kinase (401 aa) fasta scores; opt: 731, FT z-score: 799.1, E(): 0, (36.7% identity in 398 aa overlap) FT and TR:Q53893 (EMBL:U51332) two component sensor kinase for FT the regulation of antibiotic production (571 aa) fasta FT scores; opt: 429, z-score: 469.2, E(): 8.4e-19, (29.5% FT identity in 407 aa overlap). Contains possible membrane FT spanning hydrophobic regions." FT /db_xref="GOA:Q9S2S0" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9S2S0" FT /protein_id="CAB51250.1" FT /translation="MSTLARARCVFGAHPSAMDTVLAVVVLVCMVAGSFVDPHGPESVS FT WGLRTPDALSLALMTAGAAALAFRRRQPMAVLVVTGCVSVVESITGDPRAPVVMSAVIA FT LYTVAASTDRPTTWRVGLLTMTVLTGAAMLAGPLPWYAQENLAVFAWTGIGATAGDAVR FT SRRAFVQAIRDRAEKAERTREEEARRRVAEERLRIARDLHDVVAHHIALVNVQAGVASH FT VMDKRPDQAKEALAHVREASRSALDELRATVGLLRQSGDPEAPTEPAPGLARLDELVAT FT FHHAGLRVEVARTDQGTELPAAVDLAAYRIIQEALTNVQKHAGRQAKAEVSVVRVGPDI FT EVTVLDDGTADGEVPDGTTEGGGHGLLGMRERVTAVRGTLTTGPRYGGGFRVHAILPVK FT SRTDAAAQATEATGDPV" FT CDS complement(229727..230011) FT /transl_table=11 FT /gene="SCO2167" FT /gene_synonym="SC5F7.34c" FT /product="hypothetical protein" FT /note="SC5F7.34c, unknown, len: aa;" FT /db_xref="UniProtKB/TrEMBL:Q9S2R9" FT /protein_id="CAB51251.1" FT /translation="MIVRIMGEGQLTLADGRLGELNKLDDELLAEMENGDGPGFRATLQ FT ALLAKVRELGEPLPDDTLEPSDLILPSPDATLEEVQELLSDDGLIPGGA" FT CDS complement(230033..230812) FT /transl_table=11 FT /gene="SCO2168" FT /gene_synonym="SC5F7.33c" FT /product="hypothetical protein" FT /note="SC5F7.33c, unknown, possible hydrophilic protein, FT len: 259aa; some similartity to others of undefined FT function eg. SW:Y617_SYNY3 hypothetical protein from FT Synechocystis sp. strain PCC6803 (267 aa) fasta scores; FT opt: 313, z-score: 322.8, E(): 1.2e-10, (30.6% identity in FT 232 aa overlap). Contains probable coiled coil regions FT approx. 35-55aa and 45-110aa." FT /db_xref="InterPro:IPR007157" FT /db_xref="UniProtKB/TrEMBL:Q9S2R8" FT /protein_id="CAB51252.1" FT /translation="MIFRAKANKALDRAEDPRETLDYSYQKQLELLQKVRRGVADVATS FT RKRLELQLNQLQSQSGKLEDQGRKALALGREDLAREALSRRAALQQQVTDLETQHATLQ FT GEEEKLTLAAQRLQAKVDAFRTKKETIKATYTAAQAQTRIGEAFSGISEEMGDVGLAIQ FT RAEDKTAQLQARAGAIDELLASGALDDQSGMHKDDIQAELDRLSGGTDVELELQRMKAE FT LAGGSTSDRQAIEGGQGQGEASSQSQQPQDTPRFDKQ" FT CDS 230994..231749 FT /transl_table=11 FT /gene="SCO2169" FT /gene_synonym="SC5F7.32" FT /product="putative integral membrane protein" FT /note="SC5F7.32, possible integral membrane protein, len: FT 251aa; contains possible membrane spanning hydrophobic FT regions. some similarity to TR:O32952 (EMBL:Z98741) FT hypothetical protein from Mycobacterium leprae (247 aa) FT fasta scores; opt: 335, z-score: 361.2, E(): 8.8e-13, FT (34.4% identity in 221 aa overlap)." FT /db_xref="UniProtKB/TrEMBL:Q9S2R7" FT /protein_id="CAB51253.1" FT /translation="MLPGLSGKSRCPGLYAASAPYIRSVPIQTTGVAGSFPTGLGSTPP FT HPVPLGFVFRSRAKDEKAQSAVSAQVTDSNQPRDPQAPKGRPTPKRSVAQSQRRSVANT FT PMTRKDAAKRQREERRTAMARQREALAKGDERYLPARDKGPVRKFARDFVDSRFNIAEY FT FLPMAVIILVLSMIRVASLQNVALLLWLVVIVLIVLDSIVTGFRLKKRLAERFPDERRR FT GAVAYALMRSLQMRRLRLPKPQVKRGERP" FT CDS 231833..232534 FT /transl_table=11 FT /gene="SCO2170" FT /gene_synonym="SC5F7.31" FT /product="putative methyltransferase" FT /note="SC5F7.31, possible methyltransferase, len: 233 aa; FT similar to SW:SMTA_ECOLI methyltransferase from Escherichia FT coli (261 aa) fasta scores; opt: 301, z-score: 359.0, E(): FT 1.2e-12, (31.1% identity in 212 aa overlap)." FT /db_xref="GOA:Q9S2R6" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:Q9S2R6" FT /protein_id="CAB51254.1" FT /translation="MARQLDEQIAGRFAVGRRLRVLDVGMGQGTQALRLARAGHQVTGV FT ERDATMIAAARDALAGQPEGIRERMRIVEGDGRDTGVHFLPGSFDVVLCHGVLMYVEEP FT DPLLAGLARMLAPGGLLSLVVRNGDALALRPGLHGDWPGALAAFDTTSYRNRLGLDVRA FT DRLATLTAKLAGIGAPLHTWYGVRVFTDTAPDGAPPPADLDALLAAEERAGRTDPYRSV FT AALLHLCGVRG" FT CDS 232636..233724 FT /transl_table=11 FT /gene="SCO2171" FT /gene_synonym="SC5F7.30" FT /product="putative secreted protease" FT /note="SC5F7.30, probable secreted protease, len: 362aa; FT similar to many egs. SW:HTRA_ECOLI Protease Do from FT Escherichia coli (474 aa) fasta scores; opt: 505, z-score: FT 503.1, E(): 1.1e-20, (39.1% identity in 294 aa overlap). FT Contains possible membrane spanning hydrophobic regions. FT Also contains Pfam matches to entry PF00089 trypsin, FT Trypsin and to entry PF00595 PDZ, PDZ domain (Also known as FT DHR or GLGF)." FT /db_xref="GOA:Q9S2R5" FT /db_xref="HSSP:1LCY" FT /db_xref="InterPro:IPR001254" FT /db_xref="UniProtKB/TrEMBL:Q9S2R5" FT /protein_id="CAB51255.1" FT /translation="MDTSRTRLRRLLAPVAVPACVLLLATGCSDAGAGTDRGSGSAREG FT DTAQAAAPRAASELEADYERVIKDVLPSVVQIQAGDSLGSGVVYDDKGHVVTNAHVVGD FT AKSFRVTTARTEGALTAKLVSSYPEQDLAVIKLDKVPEGMRAARFADSAKVEVGQIVLA FT MGSPLGLSSSVTQGIVSATGRTVTEGSSGGGTGATIANMVQTSAAINPGNSGGALVNLD FT GQVIGIPTLAATDPGLGDSAAPGIGFAIPASMVTTVAGQIVRDGKVTDSGRAALGITAR FT TVVDDSYRPAGAAVVEVSDGGAADDAGLRPGDVLVKLGDTDITTITSLSEALASMRPGD FT RTKVTYTRDGKEHTAEVTLGEQ" FT misc_feature 232825..233412 FT /note="Pfam match to entry PF00089 trypsin, Trypsin, score FT -0.30, E-value 0.00012." FT misc_feature 233434..233682 FT /note="Pfam match to entry PF00595 PDZ, PDZ domain (Also FT known as DHR or GLGF)., score 42.60, E-value 8.8e-09." FT CDS complement(233755..234003) FT /transl_table=11 FT /gene="SCO2172" FT /gene_synonym="SC5F7.29c" FT /product="hypothetical protein" FT /note="SC5F7.29c, unknown, len: 82aa;" FT /db_xref="UniProtKB/TrEMBL:Q9S2R4" FT /protein_id="CAB51256.1" FT /translation="MAAWTWRFETADGTEVQPAVQPEEFTTQGDAESWIGEQWKDLRAG FT GTDQVRLFEDSTEIYGPMSLHAEEAEADAEAEAGTEA" FT CDS 234218..235411 FT /transl_table=11 FT /gene="SCO2173" FT /gene_synonym="SC5F7.28" FT /product="putative adenosylcobinamide FT kinase/adenosylcobinamide phosphate guanylyltransferase" FT /note="SC5F7.28, putative adenosylcobinamide FT kinase/adenosylcobinamide phosphate guanylyltransferase, FT len: 397 aa; regions similar to different proteins. 1-220aa FT similar to TR:O05479 (EMBL:M86351) triacylglycerol FT acylhydrolase from Streptomyces sp. (481 aa) fasta scores; FT opt: 146, z-score: 158.6, E(): 0.17, (30.4% identity in 207 FT aa overlap). 220-397aa similar to many bifunctional FT adenosylcobinamide kinase/adenosylcobinamide phosphate FT guanylyltransferase proteins in the biosynthesis of FT cobalamin (vitamin B12) eg. SW:COBU_SALTY FT adenosylcobinamide kinase/adenosylcobinamide phosphate FT guanylyltransferase from Salmonella typhimurium (181 aa) FT fasta scores; opt: 368, z-score: 398.3, E(): 7.5e-15, FT (41.7% identity in 175 aa overlap)." FT /db_xref="GOA:Q9S2R3" FT /db_xref="HSSP:1C9K" FT /db_xref="InterPro:IPR003203" FT /db_xref="UniProtKB/TrEMBL:Q9S2R3" FT /protein_id="CAB51257.1" FT /translation="MTLLGTGAPAGLPRPDCPCAACAAAQGEDARAATALLVDGALLLD FT LTPGAAFAAARAGHSLSGVRQVLLSHPHDGPAVEVPAGLPQPGRVPDGRELALLTGHRV FT RAVALDAPGTGYAVTGPDGRRLLYVPPGGAPAGLEEPVEPYDLVLADVVGRPDALARLR FT AVGAAGPTTDVVAVHLDHDVPPGRELARRLAAAGARTVPDGTTLAVGSYEDVPDVPRRT FT LVLGGARSGKSVEAERRLEPFPDVLYVATGGSRNGDTEWAARVGAHRERRPGSWRTAET FT CDLVPLLKDEGPPLLVDCLSLWLTDAMDAVGAWDDEEWADGGERALRDRVRELTQAVRG FT TRRTLVAVSNEVGSGIVPATASGRRYRDELGRLNAAFAAECEQVLLVVAGQALVLRG" FT CDS complement(235400..236170) FT /transl_table=11 FT /gene="SCO2174" FT /gene_synonym="SC5F7.27c" FT /product="putative transferase" FT /note="SC5F7.27c, possible transferase, len: 256 aa; region FT (120-210aa) similar to SW:UBIG_SALTY 3-demethylubiquinone-9 FT 3-methyltransferase from Salmonella typhimurium (209 aa) FT fasta scores; opt: 142, z-score: 165.2, E(): 0.073, (31.6% FT identity in 98 aa overlap)" FT /db_xref="GOA:Q9S2R2" FT /db_xref="InterPro:IPR013217" FT /db_xref="UniProtKB/TrEMBL:Q9S2R2" FT /protein_id="CAB51258.1" FT /translation="MPGMSYVPAYVSCREPLVSATSAPSVPPVPPYGPYREDCPWCGSR FT RLRARLRGDGPRQGAPHRSPVERCADCRHVFRNPPLTPGPEHPLVRAGVRFRHRLAARA FT LYRHCPEPESWLDVGTGDAEFPRTARTHFPYTAFDGLDATHRVLRARAVERVEEAFVGR FT LTDPHIAARLRERYDVVSLFQYLERVVDPRAELRAALRVLRPGGHLLVDVADPRRLLPV FT HPLGLGAELVAQGCTVLTGSRGHRVVARKDGSAP" FT CDS 236274..237347 FT /transl_table=11 FT /gene="SCO2175" FT /gene_synonym="SC5F7.26" FT /product="putative FT nicotinate-nucleotide-dimethylbenzimidazole FT phosphoribosyltransferase" FT /note="SC5F7.26, possible FT nicotinate-nucleotide-dimethylbenzimidazole FT phosphoribosyltransferase, len: 357 aa; similar to FT SW:COBT_SALTY nicotinate-nucleotide-dimethylbenzimidazole FT phosphoribosyltransferase, cobalamin (vitamin B12) FT biosynthetic gene from Salmonella typhimurium (356 aa) FT fasta scores; opt: 509, z-score: 554.1, E(): 1.6e-23, FT (32.3% identity in 347 aa overlap). Also similar to FT SW:COBT_MYCTU putative FT nicotinate-nucleotide-dimethylbenzimidazole FT phosphoribosyltransferase from Mycobacterium tuberculosis FT (361 aa) fasta scores; opt: 939, z-score: 1016.0, E(): 0, FT (44.9% identity in 334 aa overlap)." FT /db_xref="GOA:Q9S2R1" FT /db_xref="HSSP:1L5O" FT /db_xref="InterPro:IPR017846" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2R1" FT /protein_id="CAB51259.1" FT /translation="MSSLNLDDFTDLIERPDGGVRRDAEARRERQVVPPGSLGRLDDLG FT EWLSAAQSAVPVRPVVRPRVVLFAGDHKVAELGVSARPAGSAGELVREVLEGGRPVSVL FT ARRLDVPVRVVDMALDCDPETLPAEVAGHRVRRGGGRIDIEDALTPEEAEAAFRAGMAV FT ADEEADSGTDLVVLGDVSVGGTTAAGTLVAALCGTDASVVTGRGGLPIDDLAWMRKCAA FT IRDALRRARPVLGDQLQLLATVGGADLTAMTGFLLQSAVRKVPVILDGVVTAACALVGQ FT RVAFRAPDWWLAAHDSGEPGQAKALDRMAMEPLLTQGVKVGEGAGGLLALPLVQAAASL FT AAELPTTADGEAVTDGE" FT CDS complement(237770..238510) FT /transl_table=11 FT /gene="SCO2176" FT /gene_synonym="SC5F7.25c" FT /product="putative integral membrane protein" FT /note="SC5F7.25c, possible integral membrane protein, len: FT 246 aa; similar to TR:O53514 (EMBL:AL021957) putative FT integral membrane protein from Mycobacterium tuberculosis FT (295 aa) fasta scores; opt: 468, z-score: 539.2, E(): FT 1.1e-22, (42.3% identity in 260 aa overlap). Contains FT possible membrane spanning hydrophobic regions. Also FT contains Pfam match to entry PF00499 oxidored_q3, FT NADH-ubiquinone/plastoquinone oxidoreductase chain 6" FT /db_xref="UniProtKB/TrEMBL:Q9S2R0" FT /protein_id="CAB51260.1" FT /translation="MGDWWQRNIMEPGKLPLLLALAAFVLTFAVTRVITRLIRAGKGPF FT GNVKAGGVHIHHVVPGVVLTVVGGFGAVAGGRHGVWSALAAVVFGIGAGLVLDEFALIL FT HLDDVYWSEAGRKSVEAVVLTAALVGLVLAGFTPFGVDGMSQDELQDRANVIATVAGNF FT LFSLLALAKGKARLAIFGVIVPLIALVGAVRLARPGSPWARRFYARRPRARARARLRAE FT RHDRRWSGPRRVVQDWIGGRPDPR" FT misc_feature complement(237920..238351) FT /note="Pfam match to entry PF00499 oxidored_q3, FT NADH-ubiquinone/plastoquinone oxidoreductase chain 6, score FT -66.80, E-value 0.52." FT CDS 238571..239353 FT /transl_table=11 FT /gene="SCO2177" FT /gene_synonym="SC5F7.24" FT /product="putative cobalamin (5'-phosphate) synthase" FT /note="SC5F7.24, possible cobalamin (5'-phosphate) FT synthase, len: 260 aa; similar to many e.g. SW:COBS_SALTY FT cobalamin (5'-phosphate) synthase from Salmonella FT typhimurium (247 aa) fasta scores; opt: 309, z-score: FT 331.0, E(): 4.2e-11, (34.0% identity in 247 aa overlap). FT Contains possible membrane spanning hydrophobic regions" FT /db_xref="GOA:Q9S2Q9" FT /db_xref="InterPro:IPR003805" FT /db_xref="UniProtKB/TrEMBL:Q9S2Q9" FT /protein_id="CAB51261.1" FT /translation="MLRTPSPDGLRFAFGTLTVLPVKVTRWDRDAARGGMLCAPLAGLA FT VGAAAAAAGLLLLALGAGTLLAAVATAAVPAVLTRGLHLDGLADTADGLGSGKPAEDAL FT RIMKQSDIGPFGVLALLFTLLAQVAALAQAYDGSWARGALAAVVSATAARLALTTAART FT GVPAARPEGLGAAVAGVVPAGGALAATAAVTLAGAAAGAYLGPYDALRTALAVVCAVAV FT AELLLRHCVRRFGGVTGDVFGGVAETAATTALVVLVLG" FT CDS complement(239371..240219) FT /transl_table=11 FT /gene="SCO2178" FT /gene_synonym="SC5F7.23c" FT /product="putative endo alpha-1,4 polygalactosaminidase" FT /note="SC5F7.23c, possible endo alpha-1,4 FT polygalactosaminidase, possibly secreted, len: 282 aa; FT similar to TR:Q52423 (EMBL:D14846) endo alpha-1,4 FT polygalactosaminidase from Pseudomonas sp.881 (294 aa) FT fasta scores; opt: 759, z-score: 748.2, E(): 0, (44.2% FT identity in 278 aa overlap). Contains possible N-terminal FT signal sequence" FT /db_xref="InterPro:IPR004352" FT /db_xref="UniProtKB/TrEMBL:Q9S2Q8" FT /protein_id="CAB51262.1" FT /translation="MRRPVLPTALLLLLLAGCTSAPGGDGGVGGVGGEGGEGGEGGDGG FT VGATAGHWRPTPGTAWQWQLSGRLDTSVDVPVYDIDGFDHDEATVAGLHDDGRKVICYV FT STGAWEDFRPDADAFPKKVLGKGNGWEGERWLDIRATDVLEPLMAERLDMCRDKGFDAV FT EPDNMDGYKNDTGFPLTGDDQLRYNRLIAKLAHDRGMAVGLKNDLDQIPDLVDDFDFAV FT NEQCAQYGECADNRPFVDADKAVFHVEYELPTERFCADSRELRLSSMLKKYELDAWREA FT C" FT CDS 240474..242027 FT /transl_table=11 FT /gene="SCO2179" FT /gene_synonym="SC5F7.22" FT /product="putative aminopeptidase" FT /note="SC5F7.22, probable aminopeptidase, len: 517aa; FT similar to SW:AMPA_ECOLI aminopeptidase from Escherichia FT coli (503 aa) fasta scores; opt: 844, z-score: 868.2, E(): FT 0, (34.7% identity in 522 aa overlap). Contains Pfam match FT to entry PF00883 Peptidase_M17, Cytosol aminopeptidase FT family and Prosite match to PS00631 Cytosol aminopeptidase FT signature." FT /db_xref="GOA:Q9S2Q7" FT /db_xref="HSSP:1BPN" FT /db_xref="InterPro:IPR008283" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2Q7" FT /protein_id="CAB51263.1" FT /translation="MTALTLSTAAAPGLRADAIVIGVAKGAGGPSVAPGAEAVDKAYDG FT RLAAVLETLGASGAEGEVTKLPAPSGFKAPVVVAVGLGAEPEKDAGFDPEALRRAAGAA FT ARALAGAKKAAFALPLAEAADAGVVAEGLLLGAYSFDAYKASAKEAKEAKGAKAKANGN FT GKAPLAEAALLGGKPRDKAYKAAIERATAVAEELNRARDLVNTPPNDLDPEAFAAVAQA FT AAKEHGIKVQVLDEKALVKGGYGGILGVGAGSASGPRLVKLSYTSPKAKKSLAFVGKGI FT TYDSGGISLKPAGHNETMKCDMAGAAAVFAAVVAAARLGLEVNVTGWLALAENMPSGSA FT TRPGDVLRMYSGKTVEVLNTDAEGRLVLADALWAASQDEPDAIIDVATLTGAMMLALGS FT RTYGIMANDDAFRSAVHEAAEESGEPAWPMPLPEHLRKGMDSPTADIANMGERMGGGLV FT AGLFLREFVGEGITWAHLDIAGPAFNEGGPFGYTPKGGTGTAVRTLVRVAELAAAGELG FT " FT misc_feature 240645..241901 FT /note="Pfam match to entry PF00883 Peptidase_M17, Cytosol FT aminopeptidase family, score 489.60, E-value 2.5e-143." FT misc_feature 241548..241571 FT /note="PS00631 Cytosol aminopeptidase signature." FT CDS 242272..243732 FT /transl_table=11 FT /gene="SCO2180" FT /gene_synonym="SC5F7.21" FT /gene_synonym="pdhL" FT /product="putative dihydrolipoamide dehydrogenase" FT /note="SC5F7.21, pdhL, probable dihydrolipoamide FT dehydrogenase, len: 486 aa; note possible downstream FT translational start sites. Similar to many prokaryote and FT eukaryote egs. TR:Q9Z6I5 (EMBL: AF047034) dihydrolipoamide FT dehydrogenase from Streptomyces seoulensis (462 aa) fasta FT scores; opt: 2780, z-score: 3088.0, E(): 0, (90.3% identity FT in 462 aa overlap), TR:Q54101 (EMBL:L38646) NADH ferredoxin FT oxidoreductase from Saccharopolyspora erythraea (456 aa) FT fasta scores; opt: 1918, z-score: 2131.8, E(): 0, (64.2% FT identity in 452 aa overlap) and SW:DLDH_PEA FT dihydrolipoamide dehydrogenase from Pisum sativum (Garden FT pea) (501 aa) fasta scores; opt: 1162, z-score: 1292.6, FT E(): 0, (41.8% identity in 466 aa overlap). Contains Pfam FT match to entry PF00070 pyr_redox, Pyridine FT nucleotide-disulphide oxidoreductase class-I and Prosite FT match to PS00076 Pyridine nucleotide-disulphide FT oxidoreductases class-I active site." FT /db_xref="GOA:Q9S2Q6" FT /db_xref="HSSP:1DXL" FT /db_xref="InterPro:IPR006258" FT /db_xref="UniProtKB/TrEMBL:Q9S2Q6" FT /protein_id="CAB51264.1" FT /translation="MSGRTPAADRSLETGVAHMHGGRDVANDASTVFDLVILGGGSGGY FT AAALRGAQLGLDVALIEKNKLGGTCLHNGCIPTKALLHAGEVADQSRESEQFGVKTSFE FT GVDMAGVHKYKDEVIAGLYKGLQGLVASRKITYIEGEGRLSSPTSVDVNGQRVQGRHVL FT LATGSVPKTLPGLEIDGNRIISSDHALTLDRVPKSAIVLGGGVIGVEFASAWKSFGSEV FT TVIEGLKHLVPVEDENSSKLLERAFRKRGIKFNLGTFFQKAEYTQDGVKVTLADGKEFE FT AEVLLVAIGRGPVSQGLGYEENGVATDRGFVLVDEYMRTNVPTISAVGDLVPTLQLAHV FT GFAEGILVAERLAGLKTVPVDYDGVPRVTYCHPEVASVGLTEARAKEVYGADKVVSIKF FT PLGGNGKSRILKTAGEIKLVQVKDGAVVGVHMVGDRMGEQVGEAQLIYNWEALPAEVAQ FT LIHAHPTQNEALGEAHLALAGKPLHMHD" FT misc_feature 242374..243723 FT /note="Pfam match to entry PF00070 pyr_redox, Pyridine FT nucleotide-disulphide oxidoreductase class-I, score 440.00, FT E-value 2.1e-128." FT misc_feature 242470..242502 FT /note="PS00076 Pyridine nucleotide-disulphide FT oxidoreductases class-I active site." FT CDS 243796..245568 FT /transl_table=11 FT /gene="SCO2181" FT /gene_synonym="SC5F7.20" FT /gene_synonym="sucB" FT /product="putative dihydrolipoamide succinyltransferase" FT /note="SC5F7.20, sucB, possible dihydrolipoamide FT succinyltransferase, len: 590 aa; similar to many egs. FT TR:AAC23517 (EMBL:AF068740) dihydrolipoamide FT succinyltransferase from Pseudomonas ovalis (407 aa) fasta FT scores; opt: 847, z-score: 602.5, E(): 3.2e-26, (41.9% FT identity in 453 aa overlap) and SW:ODO2_MYCTU FT dihydrolipoamide succinyltransferase from Mycobacterium FT tuberculosis (553 aa) fasta scores; opt: 1232, z-score: FT 866.2, E(): 0, (56.2% identity in 596 aa overlap). Contains FT two Pfam matches to entry PF00364 biotin_lipoyl, FT Biotin-requiring enzymes, Pfam match to entry PF00198 FT 2-oxoacid_dh, 2-oxo acid dehydrogenases acyltransferase FT (catalytic domain) and two Prosite matches to PS00189 2-oxo FT acid dehydrogenases acyltransferase component lipoyl FT binding site." FT /db_xref="GOA:Q9S2Q5" FT /db_xref="HSSP:2PDD" FT /db_xref="InterPro:IPR004167" FT /db_xref="UniProtKB/TrEMBL:Q9S2Q5" FT /protein_id="CAB51265.1" FT /translation="MAVSVTLPALGESVTEGTVTRWLKAEGERVEADEPLLEVSTDKVD FT TEIPAPASGVLSSIKVAEDETVEVGAELALIDDGSGAPAAAPAPQAEQVAEPAPEPAPA FT APSTEQAAPAPAPTADAAAGGSAQGTDVVLPALGESVTEGTVTRWLKSVGDSVEEDEPL FT LEVSTDKVDTEIPAPASGTLLEIVVGEDETAEVGAKLAVIGAAGAAPAAAPAAPAAPAQ FT EAPAAPAQPEPTPAPAPAQAAPAPAPQAPAAPAPQPAAPAPAPAPAAAPAAPAAAQPVD FT DGAYVTPLVRKLAAENGVDLSTVKGTGVGGRIRKQDVAAAAEAAKAAAPAPAAAPAAPA FT AKKAPVLEASPLRGQTVKMPRIRKVIGDNMVKALHEQAQLSSVVEVDVTRLMKLRARAK FT DAFAAREGVKLSPMPFFVKAAAQALKAHAPVNAKINEAEGTITYFDTENIGIAVDSEKG FT LMTPVIKNAGDLNLAGIAKATADLAGKVRASKISPDELAGATFTISNTGSRGALFDTII FT VPPGQVAILGIGATVKRPAVIETEDGPVIGVRDMTYLTLSYDHRLVDGADAARYLTAVK FT AILEAGEFEVELGL" FT misc_feature 243802..244023 FT /note="Pfam match to entry PF00364 biotin_lipoyl, FT Biotin-requiring enzymes, score 106.60, E-value 4.9e-28." FT misc_feature 243874..243963 FT /note="PS00189 2-oxo acid dehydrogenases acyltransferase FT component lipoyl binding site." FT misc_feature 244183..244404 FT /note="Pfam match to entry PF00364 biotin_lipoyl, FT Biotin-requiring enzymes, score 106.30, E-value 6e-28." FT misc_feature 244255..244344 FT /note="PS00189 2-oxo acid dehydrogenases acyltransferase FT component lipoyl binding site." FT misc_feature 244882..245556 FT /note="Pfam match to entry PF00198 2-oxoacid_dh, 2-oxo acid FT dehydrogenases acyltransferase (catalytic domain), score FT 259.90, E-value 3.3e-74." FT CDS 245778..246401 FT /transl_table=11 FT /gene="SCO2182" FT /gene_synonym="SC5F7.19" FT /product="putative gntR-family transcriptional regulator" FT /note="SC5F7.19, possible gntR-family transcriptional FT regulator, len: 207aa; similar to many egs. SW:GNTR_BACSU FT gluconate operon transcriptional repressor (243 aa) fasta FT scores; opt: 192, z-score: 240.4, E(): 4.7e-06, (31.1% FT identity in 180 aa overlap) and TR:CAA22369 (EMBL:AL034443) FT putative transcriptional regulator from Streptomyces FT coelicolor (225 aa) fasta scores; opt: 242, z-score: 300.9, FT E(): 2e-09, (32.2% identity in 199 aa overlap). Contains FT Pfam match to entry PF00392 gntR, Bacterial regulatory FT proteins, gntR family." FT /db_xref="GOA:Q9S2Q4" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9S2Q4" FT /protein_id="CAB51266.1" FT /translation="MTAPVVHSLREQIREHILEGIISGRWQPGERIVERRIATELEVSQ FT TPVREALRELESLRLIESAPNKGVRVRNLTAADLEESYPVRAGLEAIAAELAADRLALD FT CSALEPHVAALYEADRVSDGTGQVRHTVGFHRELVRAAGNSVLLHTWEGLGIEVFTALS FT IRWLGTVQQSYAEEHEELVAAFRRRDPRIPEIVKSHVLGCAPRP" FT misc_feature 245814..245990 FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 52.00, E-value FT 1.7e-14." FT CDS 246740..249439 FT /transl_table=11 FT /gene="SCO2183" FT /gene_synonym="SC5F7.18" FT /gene_synonym="aceE1" FT /product="putative pyruvate dehydrogenase E1 component" FT /note="SC5F7.18, aceE1, probable pyruvate dehydrogenase E1 FT component, len: 899 aa; similar to many eg. SW:ODP1_ALCEU FT pyruvate dehydrogenase E1 component from Alcaligenes FT eutrophus fasta scores; opt: 2508, z-score: 2834.4, E(): 0, FT (51.3% identity in 887 aa overlap)." FT /db_xref="GOA:Q9S2Q3" FT /db_xref="HSSP:1L8A" FT /db_xref="InterPro:IPR004660" FT /db_xref="UniProtKB/TrEMBL:Q9S2Q3" FT /protein_id="CAB51267.1" FT /translation="MTTDPKAIQPSELDQLPDRDPEETAEWQASLDAVTQAAGPHRAAY FT LMRRTLERAEGAGLALPKLLETDYVNSIPTADEPTVDGDEAMEQRITAWNRWNAAAMVT FT RGSKYGVGGHIATFASAAWLYETGFNHFFKGKEGDGSGDQLYIQGHASPGIYARAFLDG FT RLNEEQLDNFRREAGGNGLPSYPHPRRLPWLWEFPTVSMGLGPISAIYQARFNRYLTSR FT GIKDLTNSHVWAFLGDGEMDEPESTTALTLASREGLDNLTFVINCNLQRLDGPVRANFK FT IVQELEAQFRGAGWNVIKSLWGTAWDELFQLDTTGALVRRLREVPDAQVQTYQTRDAAY FT IREDFFNKDPQLAEMAKLLSDDKILDCFHFSRGGHESRKVYAAYRAALAHKGAPTVILA FT QTVKGHTLGRGFASKNANHQMKKLSVDEFKDMRDLLGLPIADSAFVDGVVPYGHPGADS FT PEVRYLQERRAALGGPAPARRVHPLAPLPAPADKAFASFDKGSGSQNVATTMAFVRLVK FT DLVRDKETGKRWVPIVPDEARTFGMESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKNG FT QILNEGITEAGSMADFIAASTAYATHGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRG FT FLVGATAGRTTLTGEGLQHADGHSPAIAATNPAALSYDPAFAYEIAAIVKDGLRRMYGE FT AAPGEDPNVFYYLTVYNEPMPQPAKPSGVDEGIVKGLYRFNTAETAGLTPAANAPRIQL FT LGSGTAIHWTLKAQRLLAEEWGVAADVWSATSWTELRRDAMDADAALLRGEDRVPYVRR FT ALQGAEGPVLAVSDYMRQVPDQIAQWVEQDYSSLGADGFGLSDTRDAARRHFGVDAESI FT VVAALAQLARRGEVKATAVKEARERYGL" FT CDS 249510..250493 FT /transl_table=11 FT /gene="SCO2184" FT /gene_synonym="SC5F7.17" FT /product="putative transcriptional regulator" FT /note="SC5F7.17, possible transcriptional regulator, len: FT 327aa; similar to TR:O34920 (EMBL:AF027868) putative FT transcriptional regulator from Bacillus subtilis (313 aa) FT fasta scores; opt: 319, z-score: 380.6, E(): 7.3e-14, FT (27.3% identity in 330 aa overlap). Contains FT helix-turn-helix motif (+4.15 SD) 20-41aa." FT /db_xref="GOA:Q9S2Q2" FT /db_xref="InterPro:IPR001034" FT /db_xref="UniProtKB/TrEMBL:Q9S2Q2" FT /protein_id="CAB51268.1" FT /translation="MRAARLIKMVLLLQSRPTMTAAELARELEVSERTVTRDAQALSEA FT GVPVYAERGRAGGYRLVGGYRTRLTGLARGEAEALFLSGVPGALREMGLEDAASAARLK FT VSAALLPSLRDASRTAAQRFHLDAPNWFREPETPELLPAVADAVWDDRRVAARYRRGTD FT EVVRELEPYGLVLKAGVWYLCARVAGTAGDGPFRVYRIDRFTAVEAGEERFVRDDGFDL FT PAFWAERAEQFARSILRAEVVVRLSERGVRGLPYAVDALSAREALEAAGAPDADGWVTV FT ALPVESEEVAHAQLRGLGPEVEVLAPAALRERFAREARRLAELYGG" FT CDS 250501..250923 FT /transl_table=11 FT /gene="SCO2185" FT /gene_synonym="SC5F7.16" FT /product="hypothetical protein" FT /note="SC5F7.16, unknown, len: 140aa;" FT /db_xref="UniProtKB/TrEMBL:Q9S2Q1" FT /protein_id="CAB51269.1" FT /translation="MPWAGVVRGVGHVTRRGLGTRGGRGREGDAARRCGVPLRPPVPPQ FT RHDCPQRRRRGGVGPQPGRGRAVSRVRREAGRGARAGLSRARREAGRGARSGLSRARRG FT GGCGAWAGRAAYGEEGACRGVSARSGWRVNAPSLFK" FT CDS 250920..251624 FT /transl_table=11 FT /gene="SCO2186" FT /gene_synonym="SC5F7.15" FT /product="hypothetical protein" FT /note="SC5F7.15, unknown, len: 234aa;" FT /db_xref="UniProtKB/TrEMBL:Q9S2Q0" FT /protein_id="CAB51270.1" FT /translation="MTDSAPFRGRTPPGATPTHPPDKPRYAHPHRTRTGRRRHPHITIR FT RTPRAPPPPRADAGPVMDETEFWELIDAARQRADGDSEDQADLLVERLLGMDPDLVLDF FT ARHFEARYNRACTWDLWAAAWVLLGGASDDAFDFFRCWLIGQGREVYEGAVHEPDSLAE FT LLDDFDEELDGDGEELGYAADEAYEQLTGTVAPDLGIAPAPPEPLGVPIDLENDRALAE FT RLPRLWARFGPE" FT CDS complement(251659..252585) FT /transl_table=11 FT /gene="SCO2187" FT /gene_synonym="SC5F7.14c" FT /product="conserved hypothetical protein" FT /note="SC5F7.14c, unknown, len: 308aa; similar to TR:O86334 FT (EMBL:Z97188) from Mycobacterium tuberculosis (539 aa) FT fasta scores; opt: 472, z-score: 514.3, E(): 2.6e-21, FT (37.5% identity in 208 aa overlap)" FT /db_xref="GOA:Q9S2P9" FT /db_xref="InterPro:IPR002502" FT /db_xref="UniProtKB/TrEMBL:Q9S2P9" FT /protein_id="CAB51271.1" FT /translation="MCGPVKGETPCTGTMVPPGGTAHIADRADPPDSGTMRVFRGPRRA FT RERRAARIPGAVRMPTAARALLGALPGLAAVAALFLCANGVERAADADAEAVPAAATDR FT YAAPRPDIVPRSVWLGDAARAQPAPRYDDEVVAVFVHHTDTPNGYDCADVPAILRGVYQ FT GQTGARDWDDIGYNFVVDRCGTVYEGRAGGIDRPVTGAHTQGFNHRTTGIAALGTYTAG FT VPVPDELTDAIAAVAAWKLGETGTDPRAKVALVSSNGLSRYAAGATAMLPAVAGHEDGY FT QTSCPGAALSARLADIRDTAARLQGRA" FT CDS 253010..253858 FT /transl_table=11 FT /gene="SCO2188" FT /gene_synonym="SC5F7.13" FT /product="putative peptidase (putative secreted protein)" FT /note="SC5F7.13, possible peptidase (putative secreted FT protein), len: 282 aa; similar to TR:CAB38504 FT (EMBL:AL035636) putative serine protease from Streptomyces FT coelicolor (385 aa) fasta scores; opt: 873, z-score: 979.4, FT E(): 0, (49.5% identity in 281 aa overlap). Contains a weak FT Pfam match to entry PF00089 trypsin, Trypsin. Contains FT possible N-terminal region signal peptide sequence" FT /db_xref="GOA:Q9S2P8" FT /db_xref="InterPro:IPR001254" FT /db_xref="UniProtKB/TrEMBL:Q9S2P8" FT /protein_id="CAB51272.1" FT /translation="MAWVAASVLAASSSSLLTSAIRDSTLLGAVQRVMPDTTPAWFSRA FT TSALADAGFPQVFNPFENESAAEVAEPSGDSVTPAATRAAQLSTVKVEGVSGTQGREGS FT GFVYAPEHVMTNAHVVAGIDDPSVRVGGVGPAYDARVVLFDPDKDVAVLYVPDLSAPVL FT RFDEDAARGDAAVVAGYPQNGDLDLRAATVANRVRATGQNIYSDESVTREIYSIRSTVR FT PGNSGGPLLTTDGRVYGVVFARSTSDAETGYVLTAAEVAPEARDAADATRAVDTGEPVT FT S" FT misc_feature 253283..253813 FT /note="Pfam match to entry PF00089 trypsin, Trypsin, score FT -30.70, E-value 0.013." FT CDS complement(253882..254391) FT /transl_table=11 FT /gene="SCO2189" FT /gene_synonym="SC5F7.12c" FT /product="putative acetyltransferase" FT /note="SC5F7.12c, possible acetyltransferase, len: 169 aa; FT similar to SW:PTCR_ALCFA phosphinothricin acetyltransferase FT from Alcaligenes faecalis (197 aa) fasta scores; opt: 178, FT z-score: 226.5, E(): 2.8e-05, (36.0% identity in 136 aa FT overlap) and TR:O33583 (EMBL:S60706) nourseothricin FT acetyltransferase from Streptomyces noursei (190 aa) fasta FT scores; opt: 140, z-score: 180.8, E(): 0.0098, (29.3% FT identity in 150 aa overlap). Contains Pfam match to entry FT PF00583 Acetyltransf, Acetyltransferase (GNAT) family." FT /db_xref="GOA:Q9S2P7" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9S2P7" FT /protein_id="CAB51273.1" FT /translation="MIAMPAPHIRRARSEDEHPLRRIDLETWSYLHAVSPPPGPDDPFF FT RDTCGPDAHLVAELDGAVVGYVRLGFPTPLASNTHVRQIRGLAVAGAARGHGVGRALVR FT AAVEEARHEGFRRITLRVLGHNTAARGLYESEGFVVEGVQPEEFHLDGRYVDDVLMGQM FT LTALTS" FT misc_feature complement(253975..254367) FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 78.20, E-value FT 1.7e-19." FT CDS 254470..255579 FT /transl_table=11 FT /gene="SCO2190" FT /gene_synonym="SC5F7.11" FT /product="conserved hypothetical protein" FT /note="SC5F7.11, unknown, len: 369aa; similar to FT SW:Y00R_MYCTU hypothetical protein from Mycobacterium FT tuberculosis (301 aa) fasta scores; opt: 885, z-score: FT 925.1, E(): 0, (46.9% identity in 290 aa overlap)." FT /db_xref="GOA:Q9S2P6" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9S2P6" FT /protein_id="CAB51274.1" FT /translation="MGGGHVAAGHMGGGHMAAGHMGGRHMDDGHTDGGRDGRRMGDRHM FT DDGHTDGGHTDARRTHNGRTNNGRPPRDRPRIVVAGASGLIGGALARSLTADGYRVVRL FT VRRAPEGPDEVRWDPENGRVDAAGLEGCDAVVNLAGAGVGDRRWTDAYKTRIRSSRVHG FT TTALAEAVAALERPPRVFVNGSAMGYYGETGDRPVDESAPPGEGFLPGLCVEWEAAAAP FT AQKAGVRTVFTRTGLVVARGGGAWGRLFPLFRAGLGGRLGDGSQYWSFVALHDEVAAIR FT HLLDRDDLSGPFNLTAPQPVTNREVTVAMGRVLHRPTPFAVPAPVLRAALGEMAGDVLG FT SARVLPARLLESGFRFAFPEIDGAIRAAL" FT CDS 255793..257196 FT /transl_table=11 FT /gene="SCO2191" FT /gene_synonym="SC5F7.10" FT /product="putative oxidoreductase" FT /note="SC5F7.10, probable oxidoreductase, len: 467 aa; low FT similarity to many e.g. SW:PUO_MICRU putrescine oxidase FT from Micrococcus rubens (478 aa) fasta scores; opt: 195, FT z-score: 192.3, E(): 0.0022, (42.7% identity in 110 aa FT overlap)." FT /db_xref="GOA:Q9S2P5" FT /db_xref="InterPro:IPR002937" FT /db_xref="UniProtKB/TrEMBL:Q9S2P5" FT /protein_id="CAB51275.1" FT /translation="MLEPAYQADVVVVGAGIAGLAAAQRLTSAGVTTTVLEAAHAVGGR FT MATEKVDGFRLDRIGQLLSTAYPELRRTPGLDGLALLPFAPGVLLHSEGRHHHAGAPSG FT VRSARGALHAVRALASAPRSMPAPRRTVNAPGTSGRPAAAPRSRAGAPLGTAVDQARLG FT AALARLAHTPAERLLARPELPAARALAARGLPARTIDGFLRPLLAALLYDPDLTTSSRC FT ADLALRAFAGGRLTLPEGGAEALPEHMARSLPPGTVHTGVRVTSVATNAVTTAEHGVIR FT CRAVLVATDARAAAELLPGLRVPDFHPVTVVHHTTDEPPTTGAALLLDADRGGPVAHTA FT QVSQVDPSRAPAGRTLVSSTVLGPPPPDLDTAVRIHLSRLYGTPTTRWETLAVHHTPEA FT VPAMRPPHDPRRPVRLLAGLYVCGDHRDTSTAQGALHSGHRASAAILRDLGAGRPMHSA FT EPAPTAHAA" FT CDS complement(257257..258720) FT /transl_table=11 FT /gene="SCO2192" FT /gene_synonym="SC5F7.09c" FT /product="putative regulator" FT /note="SC5F7.09c, possible regulator, len: 487 aa; similar FT to others from Streptomyces spp. e.g. TR:Q53958 FT (EMBL:M80614) sporulation associated proteins from FT Streptomyces coelicolor (473 aa) fasta scores; opt: 728, FT z-score: 812.2, E(): 0, (39.7% identity in 489 aa overlap) FT and TR:O88053 (EMBL:AL031541) putative transcriptional FT regulator from Streptomyces coelicolor (446 aa) fasta FT scores; opt: 501, z-score: 560.4, E(): 7e-24, (33.8% FT identity in 459 aa overlap)." FT /db_xref="UniProtKB/TrEMBL:Q9S2P4" FT /protein_id="CAB51276.1" FT /translation="MTERPAQRTPNRQLAALIAEAGFSNAGLARRVDQLGLEHGLDLRY FT DKTSVTRWLRGQQPRGTTPALIAEVFTRRLGRRLTAQDLGLDACAPVYAGLEFAGSPEE FT AVDIVGGLWRKDSGSHAELRKIAFTPAGLVVPSRDWLIGRPDEKVARAEVPVRIPAQGR FT PATPRLAVPLDPSRRRAPAERGPGQKVSGGDLAALRSVGELFRSLDDRYGGGHARQALV FT RYLEHELEPMLRGTYGEQTGRRLFAAAADLTRLAGWTSYDIAAHGLAQRYFVQALRLSQ FT AAGDRAYGSYVLVTMSRQAVYLGHGREAVQLARVAQQGVGTSAPPVVQTLLHAAEARAH FT GLLGEVRACTAALVRAERALEAARPGDEVPHWARFFDEAQLADEFGHCHRDLQQFRAAA FT QHAERSLQLRAPVYARSRLFCRVVLATARLGLGELDQACQLAAEAAGQAAEMRSVRAAE FT YVRDFERRLEPYRDAAPVRGYRDKVAALG" FT CDS 258955..259752 FT /transl_table=11 FT /gene="SCO2193" FT /gene_synonym="SC5F7.08" FT /gene_synonym="lipB" FT /product="putative lipoate-protein ligase" FT /note="SC5F7.08, lipB, probable lipoate-protein ligase, FT len: 265aa; similar to many eg. SW:LIPB_MYCTU probable FT lipoate-protein ligase from Mycobacterium tuberculosis (230 FT aa) fasta scores; opt: 559, z-score: 652.0, E(): 5.5e-29, FT (52.0% identity in 223 aa overlap) and SW:LIPB_ECOLI FT lipoate-protein ligase B from Escherichia coli (191 aa) FT fasta scores; opt: 145, z-score: 177.0, E(): 0.016, (28.9% FT identity in 225 aa overlap). Contains PS01313 FT Lipoate-protein ligase B signature." FT /db_xref="GOA:Q8CK04" FT /db_xref="InterPro:IPR000544" FT /db_xref="UniProtKB/Swiss-Prot:Q8CK04" FT /protein_id="CAD55297.1" FT /translation="MSELRFVRMGFGADRVEYQEAWDEQRRVHAARFVDEVPDTVLLLE FT HPPVYTAGRRTEDSERPLDGTPVIDVDRGGKITWHGPGQLVGYPIQKLPRPVDVVAHVR FT RLEEALIRTCAEFGLETSRVEGRSGVWVLGDPVEQRPVLGGLSLDFDPRLSDDEFDPRL FT NGPEYAPSNAGQRREDRKIAAIGIRVAKGVTMHGFALNVNPDNKWFDKIIPCGIRDAGV FT ASLANELGRDVTIEEVLPVAERHLRDVLENAELKPRVIEKTPA" FT misc_feature 259171..259218 FT /note="PS01313 Lipoate-protein ligase B signature." FT misc_feature 259587..262134 FT /note="overlap with Streptomyces coelicolor cosmid SC5F7 FT (EMBL:AL096872)" FT RBS 259897..259900 FT CDS 259907..260860 FT /transl_table=11 FT /gene="SCO2194" FT /gene_synonym="SC5F7.07" FT /gene_synonym="lipA" FT /product="putative lipoic acid synthetase" FT /note="SC5F7.07, lipA, probable lipoic acid synthetase, FT len: 317aa; similar to many egs. SW:LIPA_MYCTU probable FT lipoic acid synthetase from Mycobacterium tuberculosis (311 FT aa) fasta scores; opt: 1564, z-score: 1838.3, E(): 0, FT (72.9% identity in 314 aa overlap) and SW:LIPA_ECOLI lipoic FT acid synthetase from Escherichia coli (321 aa) fasta FT scores; opt: 814, z-score: 959.8, E(): 0, (41.9% identity FT in 313 aa overlap)." FT /db_xref="GOA:Q9S2P2" FT /db_xref="InterPro:IPR007197" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2P2" FT /protein_id="CAB90841.1" FT /translation="MSAVAPDGRKMLRLEVRNSQTPIERKPEWIKTRAKMGPEYTKMQN FT LVKSEGLHTVCQEAGCPNIYECWEDREATFLIGGDQCTRRCDFCQIDTGKPEALDRDEP FT RRVGESVVTMDLNYATITGVARDDLPDGGAWLYAETVRQIHEQTAGREAGRTKVELLAP FT DFNAVPELLREVFESRPEVFAHNVETVPRIFKRIRPGFRYERSLKVITDARDFGLVTKS FT NLILGMGETREEISEALKQLHEAGCELITITQYLRPSVRHHPVERWVKPQEFVELKEEA FT EQIGFSGVMSGPLVRSSYRAGRLYGMAMEQRRSATV" FT CDS 261105..261320 FT /transl_table=11 FT /gene="SCO2195" FT /gene_synonym="SC5F7.06" FT /product="hypothetical protein" FT /note="SC5F7.06, unknown, len: 71aa;" FT /db_xref="UniProtKB/TrEMBL:Q9S2P1" FT /protein_id="CAB90842.1" FT /translation="MQAAPVRPTAVRATAIPSFTTALRAVESLLMSSGQRTARRNAWNS FT VLEDRRRAKDRIETERALRQSVAGRP" FT CDS 261402..262106 FT /transl_table=11 FT /gene="SCO2196" FT /gene_synonym="SC5F7.05" FT /product="putative integral membrane protein" FT /note="SC5F7.05, possible integral membrane protein, len: FT 234aa; similar to SW:Y00U_MYCTU hypothetical protein from FT Mycobacterium tuberculosis (250 aa) fasta scores; opt: 574, FT z-score: 642.0, E(): 2e-28, (39.4% identity in 226 aa FT overlap). Contains possible membrane spanning hydrophobic FT regions." FT /db_xref="UniProtKB/TrEMBL:Q9S2P0" FT /protein_id="CAB90843.1" FT /translation="MARKEPAADAANPGRLKQIALTYKMTRKADKKIGLVLAGVGIVVF FT GVLLAIGFWIGHPIYLGILGLLLAFLATAIVFGRRAERAAFGQMEGQPGAAAAVLDNIG FT RGWTTTPAVAMNRNQDVVHRAVGKAGIVLVAEGNPNRVKSLLAAEKKKMNRIVADVPVH FT DLLVGTGEGQVELKKLRTTMLKLPRVLSGPQVTVTNDRLRALGDLMSNMPLPKGPMPKG FT MRMPRGGNPKQR" FT stem_loop complement(262123..262184) FT /note="7414 ACGCCGGTACGGCGAGGGGGGCGGCCCGA 7442 - 7447 FT TCGGGCCGCCCCCCTCGCCGTACCGGCGT 7475. Score 87: 29/29 (100%) FT matches, 0 gapS" FT CDS complement(262217..262684) FT /transl_table=11 FT /gene="SCO2197" FT /gene_synonym="SC3H12.05c" FT /product="putative integral membrane protein" FT /note="SC3H12.05c, possible integral membrane protein, len: FT 155 aa; identical to previously sequenced TR:CAB51281 FT (EMBL:AL096872) Streptomyces coelicolor hypothetical 16.6 FT kD protein SC5F7.04c, 155 aa and similar to SW:YCKC_BACSU FT (EMBL:D50453) Bacillus subtilis hypothetical 17.0 kD FT protein in ComJ 5'region (ORF3) YckC, 151 aa; fasta scores: FT opt: 108 z-score: 138.4 E(): 2.5; 33.1% identity in 118 aa FT overlap. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="InterPro:IPR010432" FT /db_xref="UniProtKB/TrEMBL:Q9S2N9" FT /protein_id="CAB90844.1" FT /translation="MDNRQAIGSWLSGPRAAVEEAGADFGHRGEQLGLPEEGPGSIARP FT GRRLGALAVDWALCSLIAYGLITGSYGQTASNWALLIFFVLSVLTVGTVGFTPGKRLFG FT LRVVDLATGRPSPLRALLRSVLLCLALPALIWDRDGRGLHDRLARTVEVRI" FT RBS 262894..262900 FT CDS 262905..264314 FT /transl_table=11 FT /gene="SCO2198" FT /gene_synonym="glnA" FT /gene_synonym="SC3H12.06" FT /product="glutamine synthetase I" FT /note="SC3H12.06, glnA, glutamine synthetase I, len: 469 FT aa; identical to previously sequenced SW:GLNA_STRCO FT (EMBL:M23172) Streptomyces coelicolor glutamine synthetase FT (EC 6.3.1.2) (glutamate-ammonia ligase) GlnA, 469 aa and to FT previously sequenced TR:CAB51282 (EMBL:AL096872) FT Streptomyces coelicolor glutamine synthetase I SC5F7.03, FT 469 aa and highly similar to SW:GLN1_STRVR (EMBL:X70924) FT Streptomyces viridochromogenes glutamine synthetase I (EC FT 6.3.1.2) (glutamate-ammonia ligase I) GlnI or GlnA, 469 aa; FT fasta scores: opt: 2905 z-score: 3417.5 E(): 0; 90.6% FT identity in 469 aa overlap. Contains Pfam match to entry FT PF00120 gln-synt, Glutamine synthetase and three Prosite FT matches to entries PS00180 Glutamine synthetase signature FT 1, PS00181 Glutamine synthetase putative ATP-binding region FT signature and PS00182 Glutamine synthetase class-I FT adenylation site" FT /db_xref="GOA:P15106" FT /db_xref="HSSP:1LGR" FT /db_xref="InterPro:IPR001637" FT /db_xref="UniProtKB/Swiss-Prot:P15106" FT /protein_id="CAB90845.1" FT /translation="MFQNADDVKKFIADEDVKFVDVRFCDLPGVMQHFTLPATAFDPDA FT EQAFDGSSIRGFQAIHESDMSLRPDLSTARVDPFRRDKTLNINFFIHDPITGEQYSRDP FT RNVAKKAEAYLASTGIADTAFFGPEAEFYVFDSVRFATRENESFYHIDSEAGAWNTGAL FT EDNRGYKVRYKGGYFPVPPVDHFADLRAEISLELERSGLQVERQHHEVGTAGQAEINYK FT FNTLLAAADDLQLFKYIVKNVAWKNGKTATFMPKPIFGDNGSGMHVHQSLWSGGEPLFY FT DEQGYAGLSDTARYYIGGILKHAPSLLAFTNPTVNSYHRLVPGFEAPVNLVYSQRNRSA FT AMRIPITGSNPKAKRVEFRAPDASGNPYLAFSALLLAGLDGIKNKIEPAEPIDKDLYEL FT APEEHANVAQVPTSLGAVLDRLEADHEFLLQGDVFTPDLIETWIDFKRANEIAPLQLRP FT HPHEFEMYFDV" FT misc_feature 262956..264017 FT /note="Pfam match to entry PF00120 gln-synt, Glutamine FT synthetase, score 735.40, E-value 1.2e-233" FT misc_feature 263049..263105 FT /note="PS00180 Glutamine synthetase signature 1" FT misc_feature 263670..263717 FT /note="PS00181 Glutamine synthetase putative ATP-binding FT region signature" FT misc_feature 264057..264095 FT /note="PS00182 Glutamine synthetase class-I adenylation FT site" FT RBS 264471..264475 FT |