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EBI DbfetchID AL939110; SV 1; linear; genomic DNA; STD; PRO; 283100 BP. XX AC AL939110; AL035591; AL079332; AL096743; AL096811; AL096839; AL096844; AC AL096849; AL109848; AL132644; AL445403; AL513407; AL591322; XX DT 25-OCT-2002 (Rel. 73, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 4) XX DE Streptomyces coelicolor A3(2) complete genome; segment 7/29 XX KW . XX OS Streptomyces coelicolor OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Streptomycineae; Streptomycetaceae; Streptomyces. XX RN [1] RP 1-283100 RA Bentley S.D.; RT ; RL Submitted (09-MAY-2002) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Streptomyces sequencing team, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL sdb@sanger.ac.uk XX RN [2] RX DOI; 10.1038/417141a RX PUBMED; 12000953. RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L., RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H., RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E., RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D., RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.; RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor RT A3(2)"; RL Nature 417(6885):141-147(2002). XX DR EMBL-CON; AL645882. DR RFAM; RF01118; PK-G12rRNA. DR SILVA-LSU; AL939110. DR SILVA-SSU; AL939110. XX FH Key Location/Qualifiers FH FT source 1..283100 FT /organism="Streptomyces coelicolor" FT /strain="A3(2)" FT /mol_type="genomic DNA" FT /db_xref="taxon:1902" FT CDS 59..520 FT /transl_table=11 FT /gene="SCO1698" FT /gene_synonym="SCI30A.19" FT /product="conserved hypothetical protein" FT /note="SCI30A.19, unknown, len: 153 aa; similar to many of FT undefined function e.g. TR:P96807 (EMBL:Z92770) FT hypothetical protein from Mycobacterium tuberculosis (151 FT aa) fasta scores; opt: 639, z-score: 785.9, E(): 0, (60.8% FT identity in 148 aa overlap) and SW:NODN_RHILV nodulation FT protein from Rhizobium leguminosarum (161 aa) fasta scores; FT opt: 388, z-score: 482.2, E(): 1.6e-19, (44.8% identity in FT 145 aa overlap)" FT /db_xref="GOA:Q9S254" FT /db_xref="InterPro:IPR002539" FT /db_xref="UniProtKB/TrEMBL:Q9S254" FT /protein_id="CAB46796.1" FT /translation="MAEPRIFASADEVKAAVGEQLGYTDWLEVDQKRIDLFAEATGDHQ FT WIHVDPERAAAGPFGGTIAHGYLTLSLLPLFGPQLIRVDGVKMGVNYGTNKVRFPSPVP FT VGSRLRATAVITGVEDVKGGIQVSVAFTVEREGGDKPVCVAESVSRYYL" FT CDS complement(511..1158) FT /transl_table=11 FT /gene="SCO1699" FT /gene_synonym="SCI30A.20c" FT /product="putative transcriptional regulator" FT /note="SCI30A.20c, possible transcriptional regulator, len: FT 215 aa; similar to many e.g. TR:CAB39717 (EMBL:AL049485) FT putative regulatory protein from Streptomyces coelicolor FT (223 aa) fasta scores; opt: 330, z-score: 413.5, E(): FT 1.1e-15, (33.8% identity in 216 aa overlap) and TR:AAD13556 FT (EMBL:AF080235) LanK regulator of landomycin biosynthesis FT in Streptomyces cyanogenus S136 (192 aa) fasta scores; opt: FT 170, z-score: 218.6, E(): 7.6e-05, (31.8% identity in 154 FT aa overlap). Contains Pfam match to entry PF00440 tetR, FT Bacterial regulatory proteins, tetR family. Contains FT possible helix-turn-helix motif (+4.32 SD) 43-64aa." FT /db_xref="GOA:Q9S253" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9S253" FT /protein_id="CAB46797.1" FT /translation="MSTAAETTGGDIEPWEEVTPDAARRLLVAAVEAFAERGYHATTTR FT DIAGRAGMSPAALYIHYKTKEELLHRISRIGHTRAVAILRSAAQGEGSAAERLADAVSS FT FVRWHAGRRTTARVVQYELDALGPEAREEILTLRRQCDAAVRGIIDDGVAAGEFDVPDV FT KGTTLAVLSLCIDVARWFNVNGPRTPDEVGALYADLVLRMVGAEPSGATAQR" FT misc_feature complement(943..1083) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 60.70, E-value FT 4e-15." FT CDS complement(1219..1533) FT /transl_table=11 FT /gene="SCO1700" FT /gene_synonym="SCI30A.21c" FT /product="putative membrane protein" FT /note="SCI30A.21c, putative membrane protein, len: 104 aa. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="InterPro:IPR008024" FT /db_xref="UniProtKB/TrEMBL:Q9S252" FT /protein_id="CAB46798.1" FT /translation="MSDTPVKQQNTAAFYGQAVASFAVAMAATAIGIYQLQADAWVRAF FT LAIAVLYLVTSAFTLAKIIRDRQEVGQIVSRVDQARLDRILVEHDPFQKPGGTPAGQRP FT " FT CDS complement(1609..2760) FT /transl_table=11 FT /gene="SCO1701" FT /gene_synonym="SCI30A.22c" FT /product="putative acyl-CoA dehydrogenase" FT /note="SCI30A.22c, probable acyl-CoA dehydrogenase, len: FT 383 aa; similar to many both prokaryote and eukaryote eg. FT SW:ACDB_BACSU acyl-CoA dehydrogenase from Bacillus subtilis FT (379 aa) fasta scores; opt: 109,1 z-score: 1197.8, E(): 0, FT (43.8% identity in 377 aa overlap) and SW:ACDS_RAT acyl-CoA FT dehydrogenase from Rattus norvegicus (Rat) (412 aa) fasta FT scores; opt: 1079, z-score: 1184.2, E(): 0, (44.6% identity FT in 372 aa overlap). Contains Pfam match to entry PF00441 FT Acyl-CoA_dh, Acyl-CoA dehydrogenase." FT /db_xref="GOA:Q9S251" FT /db_xref="HSSP:1JQI" FT /db_xref="InterPro:IPR006092" FT /db_xref="UniProtKB/TrEMBL:Q9S251" FT /protein_id="CAB46799.1" FT /translation="MNLELSEEQTAVRQLARDFVEREIAPHVVEWDRAEEVDRSLVKKL FT GEVGFLGLTIDEQYGGSGGDHLAYCLVTEELGRGDSSVRGIVSVSLGLVAKTIAAWGDE FT EQKRRWLPGLTSGEYVGCFGLTEPGTGSDAGNLTTRAVRDGDDYVVNGTKMFITNGTWA FT DVVLLFARSTDAPGHQGVSAFLVPTDTPGLTRRTIHGKLGLRGQATAELVLEDVRVPAS FT AMLAPEGKGFSVAMSALAKGRMSVAAGCVGIAQAALDAAVRYAGEREQFGKTIAHHQLV FT QELISDIALDVDAARLLTWRVADLIDRGQPFAVESSKAKLFASEAAVRAANNALQVFGA FT YGYIDEYPAGKLLRDARVMTLYEGTSQIQKLVIGRALTGVSAF" FT misc_feature complement(1636..2748) FT /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA FT dehydrogenase, score 565.20, E-value 4.3e-166." FT CDS 2850..3491 FT /transl_table=11 FT /gene="SCO1702" FT /gene_synonym="SCI30A.23" FT /product="putative transcriptional regulator" FT /note="SCI30A.23, possible transcriptional regulator, len: FT 213 aa; similar to many e.g. TR:Q53901 (EMBL:M64683) FT regulatory protein from Streptomyces coelicolor (259 aa) FT fasta scores; opt: 227, z-score: 273.2, E(): 6.9e-08, FT (32.3% identity in 217 aa overlap). Contains Pfam match to FT entry PF00440 tetR, Bacterial regulatory proteins, tetR FT family and Prosite match to PS01081 Bacterial regulatory FT proteins, tetR family signature. Contains possible FT helix-turn-helix motif (+5.17 SD) 31-52aa." FT /db_xref="GOA:Q9S250" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9S250" FT /protein_id="CAB46800.1" FT /translation="MARPRKPLLSTDRIVETARALVDAEGLAAVSTRRLAAELGVSGPS FT LYNHFRTKDEILEAVADSVSAQVDLSMFEDGREWRTALHDWAVSYRTALRDHPNIVPVL FT AHGPGRRPAALHLADAVYGAMVRAGWPAAQATSIGALMRYFVMGSALGSFAGGFVDDAG FT AYDPADYPHLQQAHLLAEQQEKIDERAFETGLTALLDGLAQQYAQVAQGV" FT misc_feature 2889..3029 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 45.00, E-value FT 9.2e-11." FT misc_feature 2925..3017 FT /note="PS01081 Bacterial regulatory proteins, tetR family FT signature." FT CDS 3555..4268 FT /transl_table=11 FT /gene="SCO1703" FT /gene_synonym="SCI30A.24" FT /product="putative transcriptional regulator" FT /note="SCI30A.24, possible transcriptional regulator, len: FT 237aa; similar to many eg. SW:MERR_STRLI probable mercury FT resistance operon repressor from Streptomyces lividans (125 FT aa) fasta scores; opt: 144, z-score: 183.3, E(): 0.007, FT (38.2% identity in 89 aa overlap). Contains Pfam match to FT entry PF01022 HTH_5, Bacterial regulatory protein, arsR FT family. Contains possible helix-turn-helix motif (+3.92 SD) FT 37-58aa." FT /db_xref="GOA:Q9S249" FT /db_xref="InterPro:IPR001845" FT /db_xref="UniProtKB/TrEMBL:Q9S249" FT /protein_id="CAB46801.1" FT /translation="MTEKDAGAPGLARLAGLLADETRAACLLALLDGRAWTAGELARHA FT GVAASTLSEHLGKLVAGGLLAEERQGRHRYVRMADDRVAHLVEDLAAQVAPEAAARRPR FT TLRASSAGSAMARGRTCYDHLAGRLGIAVTDALTGRGLLRQDTGFALTDAGLGWFDSAG FT IPLRPTGRRPLARACLDWTERRPHLAGVAGAALCRHALDTGWCVRIGSERAVRVTPAGE FT DALSQLLDIDPAALR" FT misc_feature 3597..3833 FT /note="Pfam match to entry PF01022 HTH_5, Bacterial FT regulatory protein, arsR family, score 55.80, E-value FT 9.1e-13." FT CDS 4342..5316 FT /transl_table=11 FT /gene="SCO1704" FT /gene_synonym="SCI30A.25" FT /product="possible integral membrane conserved hypothetical FT protein" FT /note="SCI30A.25, possible integral membrane conserved FT hypothetical protein, len: 324aa; similar to many eg. FT SW:YDFC_BACSU hypothetical protein from Bacillus subtilis FT (306 aa) fasta scores; opt: 485, z-score: 529.4, E(): FT 3.7e-22, (34.2% identity in 269 aa overlap). Contains 2 FT Pfam matches to entry PF00892 DUF6, Integral membrane FT protein and several possible membrane spanning hydrophobic FT regions." FT /db_xref="GOA:Q9S248" FT /db_xref="InterPro:IPR000620" FT /db_xref="UniProtKB/TrEMBL:Q9S248" FT /protein_id="CAB46802.1" FT /translation="MMTTARTSPPAPWHRRPDLLAAGAATVTVVLWASAFVSIRSAGEA FT YSPGALALGRLLSGVLTLGAIWLLRREGLPPRAAWRGIAISGLLWFGFYMVVLNWGEQQ FT VDAGTAALVVNVGPILIALLGARLLGDALPPRLLTGMAVSFAGAVTVGLSMSGEGGSSL FT FGVVLCLLAAVAYAGGVVAQKPALAHASALQVTTFGCLVGAVLCLPFAGQLVHEAAGAP FT VSATLNMVYLGVFPTALAFTTWAYALARTTAGRMGATTYAVPALVVLMSWLALGEVPGL FT LTLAGGALCLAGVAVSRSRRRPAAVPDRAAPTAEPRREDAGRA" FT misc_feature 4429..4821 FT /note="Pfam match to entry PF00892 DUF6, Integral membrane FT protein, score 27.00, E-value 0.00045." FT misc_feature 4861..5268 FT /note="Pfam match to entry PF00892 DUF6, Integral membrane FT protein, score 58.40, E-value 1.5e-13." FT CDS complement(5567..6664) FT /transl_table=11 FT /gene="SCO1705" FT /gene_synonym="SCI30A.26c" FT /product="putative alcohol dehydrogenase (zinc-binding)" FT /note="SCI30A.26c, probable alcohol dehydrogenase FT (zinc-binding), len: 365 aa; similar to many e.g. FT SW:ADH3_ECOLI alcohol dehydrogenase class III from FT Escherichia coli (369 aa) fasta scores; opt: 819, z-score: FT 864.3, E(): 0, (38.6% identity in 368 aa overlap). Contains FT Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases and Prosite matche to PS00059 FT Zinc-containing alcohol dehydrogenases signature." FT /db_xref="GOA:Q9S247" FT /db_xref="HSSP:1F8F" FT /db_xref="InterPro:IPR013154" FT /db_xref="UniProtKB/TrEMBL:Q9S247" FT /protein_id="CAB46803.1" FT /translation="MAVRTAVRAAVVPAPGAPLEVTGIELPEPGPGRVRVRLAAAGVCH FT SDLSLSNGTMRVPLPAVLGHEGAGTVVAVGEGVTHVAPGDEVVLNWAPSCGACHACSLG FT EVWLCAHALAGAADVHARRADDGTDLHPGLNVAAFAEETVVAASCVLPAPEGIPLTEAA FT LLGCAVLTGYGAVHHSARVREGETVAVFGVGGVGLATLQAARIAGASKIVAVDVSPEKE FT ELARAAGATDYLLASDTTAREIRALTGKQGVDVAVECVGRAVTIRTAWESTRRGGRTTV FT VGIGGKDQQVTFNALEIFHWGRTLSGCVYGNADPARDLPVLAEHVRAGRLDLGALVTER FT IALDGIPAAFDNMLAGKGGRALVVF" FT misc_feature complement(5573..6640) FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score 338.50, E-value 7.6e-98." FT misc_feature complement(6431..6475) FT /note="PS00059 Zinc-containing alcohol dehydrogenases FT signature." FT CDS complement(6688..8076) FT /transl_table=11 FT /gene="SCO1706" FT /gene_synonym="SCI30A.27c" FT /product="putative aldehyde dehydrogenase" FT /note="SCI30A.27c, probable aldehyde dehydrogenase, len: FT 462 aa; similar to many e.g. TR:O33455 (EMBL:U24215) FT P-cumic aldehyde dehydrogenase from Pseudomonas putida Fl FT (494 aa) fasta scores; opt: 1109, z-score: 1142.8, E(): 0, FT (44.6% identity in 471 aa overlap) and TR:O88069 FT (EMBL:AL031541) putative aldehyde dehydrogenase from FT Streptomyces coelicolor (483 aa) fasta scores; opt: 1011, FT z-score: 1042.5, E(): 0, (41.8% identity in 466 aa FT overlap). Contains Pfam match to entry PF00171 aldedh, FT Aldehyde dehydrogenase and Prosite match to PS00687 FT Aldehyde dehydrogenases glutamic acid active site." FT /db_xref="GOA:Q9S246" FT /db_xref="HSSP:1O04" FT /db_xref="InterPro:IPR016162" FT /db_xref="UniProtKB/TrEMBL:Q9S246" FT /protein_id="CAB46804.1" FT /translation="MKAHDGMYIDGAWRPADGRDTIDVVNPVDEQVIGKVPAGSALDVD FT TAVRAARAALSGWAATPPAERAARLAALRDVLVARKDEIAETVTAELGSPLKFSQAVHA FT GAPIAVAGSYAELAATHAFEEKVGNSVVHHEPVGVVGAITPWNYPLHQIVAKAAPALAA FT GCTMVLKPAEDAPLVAQLFAEAVHEAGIPAGVFNLVTGLGPVAGQALVEHPGVDLVSFT FT GSTAVGRRIGATAGAAVKRVALELGGKSANVILPSADLAKAVNVGVANVMSNSGQTCSA FT WTRMLVHRDQYDEAVSLAAEAAAKYGDRIGPVVNAEQRERVRGYIGKGVAEGARLVAGG FT PEAPREQGYFVSPTVFADVTEEMTIAQEEIFGPVLSILRYEDEDDALRIANGTVYGLAG FT AVWAGDEADAVAFARRMDTGQVDINGGRFNPLAPFGGYKQSGVGRELGAHGLTEYLQTK FT SLQF" FT misc_feature complement(6691..8043) FT /note="Pfam match to entry PF00171 aldedh, Aldehyde FT dehydrogenase, score 560.20, E-value 1.4e-164." FT misc_feature complement(7324..7347) FT /note="PS00687 Aldehyde dehydrogenases glutamic acid active FT site." FT CDS complement(8201..9538) FT /transl_table=11 FT /gene="SCO1707" FT /gene_synonym="SCI30A.28c" FT /product="putative ABC sugar transporter, ATP-binding FT subunit" FT /note="SCI30A.28c, probable ABC sugar transporter, FT ATP-binding subunit, len: 445aa; similar to many eg. FT TR:AAD24578 (EMBL:AF126010) trehalose/maltose transport FT ATP-hydrolysing subunit from hyperthermophilic archaeon FT Thermococcus litoralis (372 aa) fasta scores; opt: 975, FT z-score: 1068.2, E(): 0, (50.1% identity in 335 aa FT overlap). Contains Pfam match to entry PF00005 ABC_tran, FT ABC transporter and Prosite matches to PS00211 ABC FT transporters family signature and PS00017 ATP/GTP-binding FT site motif A (P-loop)." FT /db_xref="GOA:Q9S245" FT /db_xref="HSSP:1G29" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9S245" FT /protein_id="CAB46805.1" FT /translation="MTRAISLHDVSKTYARGVRVVDRLSLDIAPGEFLVLLGPSGCGKS FT TVLRMIAGLEEITEGELTLDGAYANDLLPAERRMAMVFQNFALYPNMTTRGNIGFPLRV FT EDPQTDHTPRVDATARMLGIEDLLDRLPAQLSGGERQRVAMGRAISRHPTAFLMDEPLS FT NLDAKLRNHLRAEITRLTRELGVTTIYVTHDQSEAMSLGDRVAVLRGGVLQQVDTPRAV FT YALPRNVFVAAFIGTPRINLLRGLVRAPLDGAMTISLGKQFLRLPEPLSLDHQLLRVQQ FT GREVIVGLRSEAVRIAKPSSARPGEVLLTGLVEHVEFQGHEVLVHFNTGSQPAVVPDLE FT APRPAARPVRRRRRDGTVLERLRERAGALRAGPVVVMDEPPEPGPAVAAPDGRLPGDLI FT VRTTPDIDLRHGMQVPLLVDLAHLFVFDQHGDRICPAPARLPDLEE" FT misc_feature complement(8906..9448) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 210.00, E-value 3.7e-59." FT misc_feature complement(9092..9136) FT /note="PS00211 ABC transporters family signature." FT misc_feature complement(9404..9427) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS complement(9762..9962) FT /transl_table=11 FT /gene="SCO1708" FT /gene_synonym="SCI30A.29c" FT /product="putative membrane protein" FT /note="SCI30A.29c, putative membrane protein, len: 66 aa. FT Contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9S244" FT /protein_id="CAB46806.1" FT /translation="MILIVLSVVLLLVVGGCVCVVWAGRGGPSWTRAVATATLAAGELV FT RASRRSDGRRGGGGPDGSSDG" FT CDS complement(9965..11356) FT /transl_table=11 FT /gene="SCO1709" FT /gene_synonym="SCI30A.30c" FT /product="putative integral membrane transport protein" FT /note="SCI30A.30c, possible integral membrane transport FT protein, len: 463aa; weak similarity to many eg. TR:Q45632 FT (EMBL:L13418) maltose permease from Bacillus FT stearothermophilus (394 aa) fasta scores; opt: 220, FT z-score: 200.9, E(): 0.00074, (28.7% identity in 363 aa FT overlap). Contains a 13x9bp degenerate repeat G/S)GA in the FT C-terminal region similar to one found in the N-terminal FT region of TR:Q94673 (EMBL:U72957) merozoite surface FT protein-2 of Plasmodium falciparum (176 aa) fasta scores; FT opt: 237, z-score: 219.6, E(): 6.7e-05, (45.4% identity in FT 97 aa overlap). Also contains possible membrane spanning FT hydrophobic regions." FT /db_xref="GOA:Q9S243" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9S243" FT /protein_id="CAB46807.1" FT /translation="MVPSGNRGWLLRLVIAFGFAQAAVSMARPAVSYRALALGADERAV FT GVIAGVYALLPLFAAVPLGRRTDHGRCAPLLPAGVVLIAGGCALSGVAGSLSTMALWSG FT VMGLGHLCFVIGAQSLVARQSAPHEQDRNFGHFTIGASLGQLIGPIAAGALIGGPDMAG FT SSALALVVAGAGAAVAFTSLWRTEHPGAAKSRAQQGARVPVVSILRARGVPAGILISLS FT VLSATDILTAYLPVVGEQRGISPAVIGVLLSLRAAATIACRLVLTPLLRLLGRTVLLTV FT TCLLAALLCAGVALPVPVWALALMLVVLGFCLGVGQPLSMTTVVQAAPDEARSTALALR FT LTGNRLGQVAAPAAAGLIAGVAGVAAPFVMLGALLLLSSGVALRSPSTGTTGTTGAGGA FT GGAGGAGGTTGTAGASGASGASGASGASGASGATGRAAGPRSPEIGQDVPDRAGDSRPC FT RESRG" FT repeat_region complement(10061..10177) FT /note="13x9bp degenerate repeat translating to (G/S)GA in FT the C-terminal region of I30A.30c." FT CDS complement(11396..12847) FT /transl_table=11 FT /gene="SCO1710" FT /gene_synonym="SCI30A.31c" FT /product="putative integral membrane transport protein" FT /note="SCI30A.31c, possible integral membrane transport FT protein, len: 483aa; similar to SW:CITM_BACSU Mg2+/citrate FT complex secondary transporter from Bacillus subtilis (433 FT aa) fasta scores; opt: 687, z-score: 644.4, E(): 1.5e-28, FT (45.7% identity in 484 aa overlap). Contains Gly/Ala-rich FT region 220-250aa. Contains possible membrane spanning FT hydrophobic regions." FT /db_xref="GOA:Q9S242" FT /db_xref="InterPro:IPR004680" FT /db_xref="UniProtKB/TrEMBL:Q9S242" FT /protein_id="CAB46808.1" FT /translation="MLTILGFAMIATFLVLIMMKKMSPIAALVLIPALFCVLVGKGAHL FT GDYVIDGVSSLAPTAAMLMFAIVYFGVMIDVGLFDPIVRAILKFCKADPMRIVVGTALL FT AAIVSLDGDGSTTFMITVSAMYPLYKRLKMSLVVMTGVAAMANGVMNTLPWGGPTARAA FT TALKVDATDIFVPMIPALAVGLVAVVVLAYVLGLRERRRLGTLSLDGAPEREPETETVL FT VGAGAGTGAAGLSGAGAGAGAGAARGAAGGPGAAGDRDTGAGGESDDDFKGLDPNRPTL FT RPRLYWFNALLTLALLTAMIMELLPIPVLFLIGAALALTVNFPHIPDQKARIAAHADNV FT LNVSGMVFAAAVFTGVLTGTGMVDHMANWLVDTIPDGMGPQMGLVTGLLSLPLTYFMSN FT DGFYFGVLPVLAEAGQAHGVSTLEIARASIVGQPLHMSSPLVPAVYVLVGMAKVEFGDH FT TRFVVKWAVLTSLVILAAGILFGII" FT CDS complement(12971..15214) FT /transl_table=11 FT /gene="SCO1711" FT /gene_synonym="SCI30A.32c" FT /product="putative dehydrogenase" FT /note="SCI30A.32c, possible dehydrogenase, len: 747aa; FT similar to many e.g. TR:O53648 (EMBL:AL021928) hypothetical FT protein from Mycobacterium tuberculosis (762 aa) fasta FT scores; opt: 617, z-score: 625.8, E(): 1.6e-27, (29.9% FT identity in 762 aa overlap) and SW:FDHF_ECOLI formate FT dehydrogenase from Escherichia coli (715 aa) fasta scores; FT opt: 466, z-score: 473.3, E(): 4.9e-19, (24.0% identity in FT 716 aa overlap)." FT /db_xref="GOA:Q9S241" FT /db_xref="InterPro:IPR006657" FT /db_xref="UniProtKB/TrEMBL:Q9S241" FT /protein_id="CAB46809.1" FT /translation="MPRTALRICPLCEATCGLALTVDGSTVTAARGDRDDVFSRGFICP FT KGASFGAVDSDPDRLRAPLVRTNGELREATWEEAFDAVAAGVRPLVERYGPHSVGVVLG FT NPNVHTMAGALYPNVLLGALGSRSLFTASTLDQMPKHVSSGLLFGDANAIPVPDLDRTD FT HLLLIGANPLESNGSLCTAPDFPGRLRALKARGGTLTVVDPRRTRTAKLADRHVAIRPG FT SDALLLAAMAHVLYEEGLVDLGALAPHVGGVDDVAAAVRDFTPESVAAACDVDADVTRA FT LARELAAAPTAAVYGRIGSCTVPHGTIASWLVDVLNILTGNLDRPGGALFPQAATDRTP FT RPAGPGRGFALGRWRSRVSGHPEAKGELPLSALAEEIDTATDAGEPVRALLTIAANPVL FT SAPDGDRLDKALESLDFMVSVDPYLNETSRHAHVVLPPPPPAQSPHHDFAFNTLAVRNQ FT VRYTRPAVPLEPGRMAETEILARLTLAVTGAHGTDPAAVDALVIEQTLAKAVREPHSPA FT HGRDPAELTALLTGETGPERRLDLMLRLGPYGDGFGARPDGLTLERLLAHPHGIDLGPL FT RPRLPQPLKTRSGKVELLPAPIAADLPRLARARDARPAGLVLVGRRHLRSNNSWMHNVP FT ALTGGSNRCTLHVHPEDAARLGLRGAQPVRVTGPGGAVTAPAEVTDAVRPGVVSLPHGW FT GHDRPGTRQTHAATDPGVNVNQLLDGSALDPLSGNAVLNGVPVTLTPLTGAEL" FT CDS complement(15339..15956) FT /transl_table=11 FT /gene="SCO1712" FT /gene_synonym="SCI11.01c" FT /gene_synonym="SCI30A.33c" FT /product="putative TetR-family transcriptional regulator" FT /note="SCI11.01c, possible tetR-family transcriptional FT regulator, partial CDS, len: >158 aa; weakly similar to FT many plasmid tetracycline repressor proteins e.g. FT SW:TER1_ECOLI (EMBL:X61367), TetR, Escherichia coli plasmid FT RP1 (216 aa), fasta scores; opt: 150 z-score: 196.6 E(): FT 0.0013, 32.8% identity in 122 aa overlap. Also similar to FT TR:O54102 (EMBL:AL021529) S.coelicolor putative FT transcriptional regulator (198 aa) (31.9% identity in 72 aa FT overlap). An alternative start codon is present at codon 4. FT Contains Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family" FT /note="SCI30A.33c, partial CDS, unknown, len: >80 aa" FT /db_xref="GOA:Q8CK21" FT /db_xref="InterPro:IPR001647" FT /db_xref="PDB:3BNI" FT /db_xref="UniProtKB/TrEMBL:Q8CK21" FT /protein_id="CAD55175.1" FT /translation="MRTVSHPTPLRRAPVQRRSAERLTRILDACADLLDEVGYDALSTR FT AVALRADVPIGSVYRFFGNKRQMADALAQRNLERYAERVTERLTEAGDGGWRGALDTVL FT DEYLAMKRTAPGFSLIDFGNQIPVGDRHAVPNHRVAERLTELLSGYLGRRPDDDLRRVF FT LVAVETADTLVQLAFRVAPDGDEKIIEEARELLRAYLGRVLD" FT misc_feature complement(15741..15881) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 43.40, E-value FT 2.6e-10" FT CDS complement(15953..16057) FT /transl_table=11 FT /gene="SCO1713" FT /gene_synonym="SCI11.02c" FT /product="hypothetical protein" FT /note="SCI11.02c, hypothetical protein, len: 34 aa; unknown FT function, improbable CDS suggested by positions of putative FT start and stop codons" FT /db_xref="UniProtKB/TrEMBL:Q9S2B7" FT /protein_id="CAB50928.1" FT /translation="MSAPATLLRRLGGPAGAPGRTGDHGSPGRVGRAS" FT CDS complement(16054..16623) FT /transl_table=11 FT /gene="SCO1714" FT /gene_synonym="SCI11.03c" FT /product="putative secreted protein" FT /note="SCI11.03c, possible secreted protein, len: 189 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Contains a probable N-terminal signal sequence and FT appropriately positioned PS00013 Prokaryotic membrane FT lipoprotein lipid attachment site, so may be a lipoprotein" FT /db_xref="UniProtKB/TrEMBL:Q9S2B6" FT /protein_id="CAB50929.1" FT /translation="MSWTRGVLAVLAVCVLLLTGSAGCGSGGGEEPEAGDSATPVGKLV FT EDTDEEGRRYREVDAELAPEVGVEVQPEADDSWDVRLTVRDFRFSPEGTQAKAVAGRGV FT ARLFLDGDLLTLLRGPRYRLPAGLVPRGTHQLTVRLYADDDTVWAVDGEPVESTADITA FT SDAEPTGATQPETVEGRTVTEPAADR" FT misc_feature complement(16552..16584) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS 16834..18159 FT /transl_table=11 FT /gene="SCO1715" FT /gene_synonym="SCI11.04" FT /gene_synonym="hgd" FT /product="putative homogentisate 1,2-dioxygenase" FT /note="SCI11.04, hgd, probable homogentisate FT 1,2-dioxygenase, len: 441 aa; highly similar to eukaryotic FT homogentisate 1,2-dioxygenases e.g. SW:HGD_HUMAN FT (EMBL:U63008), hgd, Homo sapiens homogentisate FT 1,2-dioxygenase (445 aa), fasta scores; opt: 1551 z-score: FT 1809.0 E(): 0, 52.1% identity in 436 aa overlap" FT /db_xref="GOA:Q9S2B5" FT /db_xref="HSSP:1EYB" FT /db_xref="InterPro:IPR005708" FT /db_xref="UniProtKB/Swiss-Prot:Q9S2B5" FT /protein_id="CAB50930.1" FT /translation="MSGDARKTAEGLAYLSGFGNEHASEAVAGALPEGRNSPQRAPLGL FT YAEQLSGTAFTEPRAHNRRSWLYRIRPSAAHPAFTRSGNGTIRTAPFNQAVPDPNRLRW FT NPLPVPGPATDFVEGLWTLGGNGDATQRTGMAVHLYHATASMDRVFSDADGELLIVPER FT GGLLLRTEFGLLHAEPGHVALIPRGVRFRVQLLDEDARGYVCENYGAPFQLPDLGPIGA FT NGLANARDFRAPVAAYEDDESTPGPVEVVNKFCGNLWTAEYDHSPLDVVAWHGNHVPYV FT YDLRRFNVIGSISYDHPDPSIFTVLTSPSDTPGLAGVDFVVFAPRWLVGEDTFRPPYFH FT RNVMSEYMGLIEGAYDAKAEGFVPGGGSLHNMMSAHGPDRETFDRASAAELKPQRIDDG FT LAFMFETRWPVTLTPQAARAEHLQPGYDDVWQGLERHFRPLH" FT CDS 18186..18935 FT /transl_table=11 FT /gene="SCO1716" FT /gene_synonym="SCI11.05" FT /product="putative gntR-family transcriptional regulator" FT /note="SCI11.05, possible gntR-family transcriptional FT regulator, len: 249 aa; weakly similar to many FT trancriptional regulators e.g. SW:FARR_ECOLI (EMBL:X15790), FT FarR, Escherichia coli fatty acyl responsive regulator (240 FT aa), fasta scores; opt: 213 z-score: 265.9 E(): 1.8e-07, FT 25.0% identity in 232 aa overlap. Similar to others from FT S.coelicolor e.g. SCE39.14c (EMBL:AL049573) S.coelicolor FT possible gntR-family regulator (243 aa) (29.5% identity in FT 224 aa overlap). Contains probable helix-turn-helix motif FT at aa 42-63 (Score 1296, +3.60 SD). Contains Pfam match to FT entry PF00392 gntR, Bacterial regulatory proteins, gntR FT family" FT /db_xref="GOA:Q9S2B4" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9S2B4" FT /protein_id="CAB50931.1" FT /translation="MTSFAPDSIVLNRKLPLWYQVSQSLRASILGRSPRDPLRLPTEEQ FT LAGHYGVSVLTMRQALKELEDEGLITRHRRRGTFIEPHARRGAPVRLLGSVDAIVAQQS FT GMKAELLDHGTAPVPSELAEYFPQVPEVALYHRLRCDEKTGEPTNHARNYVRPELAGRI FT DLDDLARWPMTKVLRDVVGMDISRITDTVEARLADPETARLLEVPLLSPILHYTGITYD FT LEGRVLDVAVIHYRGDRFSFTVTLDAT" FT misc_feature 18246..18425 FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 46.40, E-value FT 9.1e-13" FT CDS 18943..20118 FT /transl_table=11 FT /gene="SCO1717" FT /gene_synonym="SCI11.06" FT /product="hypothetical protein" FT /note="SCI11.06, hypothetical protein, len: 391 aa; unknown FT function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition" FT /db_xref="UniProtKB/TrEMBL:Q9S2B3" FT /protein_id="CAB50932.1" FT /translation="MPRRTMPGVTHDDAPPLADLMPWSVAPPRLGRGWPTAPDAASLKA FT RWDALLKAEGPDRAALFEPTRSRTPYSAVGRLPGGAGGTERLVRAAGPCPEPVRVLRAP FT FDEQWLIPDHRLIDAARPELWRVADARQVFVVEAPEAAGGPQLLATSLLPLFGPARIRP FT LYRRPGGAEPNLAPGLPDHLAARLGRRPAPLDVLAWSAAAVRPGSLVPLTADPALWEHG FT VELGRRALWLMRRDGERPKLPGGRRPYVRAPLPPRPLVLRYDREEEALFLDEGRISPVP FT PGAWDFEVGGVRVLEQWFAARAAEGEPGTLTAIRPAGWPQSWTSELLELITVLALLAEV FT REECRELTVTDEITATELREAGVLPVPGAARRPASVLDDREEGPEGQLALL" FT CDS complement(20144..20848) FT /transl_table=11 FT /gene="SCO1718" FT /gene_synonym="SCI11.07c" FT /product="putative regulator" FT /note="SCI11.07c, possible regulator, len: 234 aa; similar FT to putative transcriptional regulators e.g. TR:O52558 FT (EMBL:AF040570), RifQ, Amycolatopsis mediterranei putative FT repressor in rafamycin biosynthetic cluster (242 aa), fasta FT scores; opt: 325 z-score: 405.5 E(): 3e-15, 33.6% identity FT in 229 aa overlap. Similar to others from S.coelicolor e.g. FT SCI30A.23 S.coelicolor possible transcriptional regulator FT (213 aa) (30.7% identity in 218 aa overlap)" FT /db_xref="GOA:Q9S2B2" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9S2B2" FT /protein_id="CAB50933.1" FT /translation="MAGRAAVPEVIWSRPERTGRGPRPAYTRADIAAAAVRIADADGLD FT AVSMRRVAGELGCGTMSLYNYVPRKEDLYELMMDAVSGEHELWEPSGDWRADMIRVAHQ FT TRALMHRHTWLPRLMSPVYGFSPNALRYLEHCLACLDPFEAPYGTKMELVAMVNGVVTT FT YVANEIATVERTRSLPWSEEQENAARIAYLGRQVASGAYPRLAASFAEDAGPIDLEGVF FT ERALARVLDGFA" FT CDS 20912..21910 FT /transl_table=11 FT /gene="SCO1719" FT /gene_synonym="SCI11.08" FT /product="putative ABC-transporter ATP-binding protein" FT /note="SCI11.08, possible ABC-transporter ATP-binding FT protein, len: 332 aa; similar to members of the FT ABC-transporter superfamily e.g. SW:DRRA_STRPE FT (EMBL:M73758), drrA, Streptomyces peucetius daunorubicin FT resistance ATP-binding protein (330 aa), fasta scores; opt: FT 901 z-score: 964.0 E(): 0, 50.6% identity in 316 aa FT overlap. Similar to many from S.coelicolor e.g. SCE9.25c FT (EMBL:AL049841) S.coelicolor probable ABC transporter FT ATP-binding component (315 aa) (57.1% identity in 308 aa FT overlap). Contains Pfam match to entry PF00005 ABC_tran, FT ABC transporter and PS00017 ATP/GTP-binding site motif A FT (P-loop)" FT /db_xref="GOA:Q9S2B1" FT /db_xref="HSSP:1JI0" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9S2B1" FT /protein_id="CAB50934.1" FT /translation="MTTTYAVLSEGLEKRFGTVRALRGLDLAVPEGTVCGLLGPNGAGK FT TTAVRLLTTLLRPDAGSARVAGHDLVREAAAVRRLIGVTGQYASVDGDLTGRQNLRLFA FT RLHRVRDAAARADELLDRFGLAEAADRPAVTLSGGLRRRLDLAASLVRRPEVLFLDEPT FT TGLDPAGRNRVWETVRALKADGTTVLLTTQYLEEADRLADDIALVDRGRVAHTGSPAEL FT KALVGTYAQAVVADADALVRAAGVLDRLTGAEPVLDHERRTVGVVSTDPTLTLPRLVRE FT LDAAGVPLADASLRPPTLDDVFLRLTGGTGSDDRNDRNDRNGSDDGKELVA" FT misc_feature 21005..21544 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 185.30, E-value 9.5e-52" FT repeat_region 21024..21054 FT /note="repeat 1; degenerate 31 bp direct repeat" FT misc_feature 21026..21049 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT repeat_region 21254..21547 FT /note="repeat 2; highly degenerate 294 bp direct repeat" FT CDS 21907..22722 FT /transl_table=11 FT /gene="SCO1720" FT /gene_synonym="SCI11.09" FT /product="putative ABC-transporter transmembrane protein" FT /note="SCI11.09, possible ABC-transporter transmembrane FT protein, len: 271 aa; similar to transmembrane subunits of FT members of the ABC-transporter superfamily e.g FT SW:DRRB_STRPE (EMBL:M73758), drrB, Streptomyces peucetius FT daunorubicin resistance transmembrane protein (283 aa), FT fasta scores; opt: 467 z-score: 550.2 E(): 2.6e-23, 34.0% FT identity in 244 aa overlap. Similar to many others from FT S.coelicolor e.g. SCE9.24c (EMBL:AL049841) S.coelicolor FT probable ABC transporter transmembrane component (260 aa) FT (41.8% identity in 268 aa overlap). Contains hydrophobic, FT possible membrane-spanning regions" FT /db_xref="GOA:Q9S2B0" FT /db_xref="InterPro:IPR013525" FT /db_xref="UniProtKB/TrEMBL:Q9S2B0" FT /protein_id="CAB50935.1" FT /translation="MSTVTTGPHGSAYGLAYDGAALLGRQLRRARNNPGLLILTQTMPI FT TMLLFFGYVFGSALAMPGEEYRAFLVPGLLVATAANGIMTGMFQAAQDTHRGVTDRLRT FT LPVSRAAVPLGQSVADVLVTAAGTVPLLLVGLAVGWRVEGGALRAVGALGLLLLFRFAT FT TWIGIFLGLLTRNEEAAGQLGGATFILPLLSNAYIPTDGLPGWLRTLAEWNPISAVTTA FT LRDLFGNAPVPDGAAWPVTHPVAGSLAWCAVLLAVFVPLAVRRYAHGGR" FT CDS complement(22947..23216) FT /transl_table=11 FT /gene="SCO1721" FT /gene_synonym="SCI11.10c" FT /product="hypothetical protein" FT /note="SCI11.10c, hypothetical protein, len: 89 aa; unknown FT function, possible CDS suggested by GC frameplot" FT /db_xref="UniProtKB/TrEMBL:Q9S2A9" FT /protein_id="CAB50936.1" FT /translation="MEQITVRSRARVPAITCGSSATSSRLDRHLAVLGGPALPPRETVE FT ATSLMRELTAREPAHKRSNRGARVRRVSLFAPLRRLRRSLFGGN" FT RBS complement(23221..23224) FT /note="possible RBS" FT CDS complement(23332..24084) FT /transl_table=11 FT /gene="SCO1722" FT /gene_synonym="SCI11.11c" FT /product="putative membrane protein" FT /note="SCI11.11c, possible membrane protein, len: 250 aa; FT unknown function, similar, except at the N-terminus, to FT SW:Y24K_STRGR (EMBL:X15060) Streptomyces griseus FT hypothetical protein (238 aa), fasta scores; opt: 274 FT z-score: 308.4 E(): 7.6e-10, 33.0% identity in 176 aa FT overlap. Also similar to TR:O53729 (EMBL:AL021932) FT mycobacterium tuberculosis hypothetical protein (232 aa) FT (31.1% identity in 241 aa overlap). Contains a hydrophobic, FT possible membrane-spanning region" FT /db_xref="GOA:Q9S2A8" FT /db_xref="InterPro:IPR018764" FT /db_xref="UniProtKB/TrEMBL:Q9S2A8" FT /protein_id="CAB50937.1" FT /translation="MSLFGHSLAAPYALDALEGAERVRFERHLEGCARCAAEVRALSED FT AVRLARSTAAPAPPALRERVLAAVRTTAQEPAPARGPVPRRSVGHVRPRPLLVPFATVT FT AAAALVVASLFAVRADRTRDELATARDRAREIAHVLAAPDARAARGADARGRGVAVVAS FT ASRGRAVVTLSGYGEPPGDRVRQLWVMRPGAEPRSLGLFDGDTPLVAAGLSRSATSLAV FT TVEPGGGSDLPTTEPVVQLALESVGFGE" FT CDS complement(24081..24638) FT /transl_table=11 FT /gene="SCO1723" FT /gene_synonym="SCI11.12c" FT /product="putative RNA polymerase sigma factor" FT /note="SCI11.12c, possible RNA polymerase sigma factor, FT len: 185 aa; weakly similar to RNA polymerase sigma factors FT e.g. SW:CARQ_MYXXA (EMBL:X71062), CarQ, Myxococcus xanthus FT RNA polymerase sigma factor (174 aa), fasta scores; opt: FT 233 z-score: 295.7 E(): 3.9e-09, 29.3% identity in 167 aa FT overlap. Similar to many putative sigma factors e.g. FT TR:O53730 (EMBL:AL021932), SigK, Mycobacterium tuberculosis FT probable RNA polymerase sigma factor (187 aa) (51.4% FT identity in 173 aa overlap). Similar to others from FT S.coelicolor e.g. TR:O54163 (EMBL:AL021411) S. coelicolor FT possible sigma factor (200 aa) (30.2% identity in 182 aa FT overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, FT Sigma-70 factor (ECF subfamily)" FT /db_xref="GOA:Q9S2A7" FT /db_xref="InterPro:IPR007630" FT /db_xref="UniProtKB/TrEMBL:Q9S2A7" FT /protein_id="CAB50938.1" FT /translation="MAGDRVAADELLVLVADGDQQAFEELYGLVSGPVFGLVRRVVRDP FT AQSEEVAQEVLLELWRSAARFDPRRGSALSWILTVAHRRAVDRVRSARAAGERDRREAH FT RSHHPAFDQVSEEVEAELEREWVRGCLDRLTALQRQSVTLAYYDGYTYREVAERLSLPL FT GTVKTRMRDGLGRLRECLGGVA" FT misc_feature complement(24327..24533) FT /note="Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 FT factor (ECF subfamily), score 31.20, E-value 2.4e-05" FT CDS 24838..26490 FT /transl_table=11 FT /gene="SCO1724" FT /gene_synonym="SCI11.13" FT /product="putative serine/threonine protein kinase" FT /note="SCI11.13, probable serine/threonine protein kinase, FT len: 550 aa; similar to eukaryotic-type protein kinases FT e.g. SW:PKAA_STRCO (EMBL:D86821), PkaA, Streptomyces FT coelicolor serine/threonine protein kinase (543 aa), fasta FT scores; opt: 628 z-score: 420.3 E(): 4.4e-16, 39.0% FT identity in 364 aa overlap, but divergent at C-terminus. FT Similar to many putative serine/threonine protein kinases FT e.g. TR:O83032 (EMBL:AB016932), PkaD, S.coelicolor FT serine/threonine protein kinase (598 aa) (49.5% identity in FT 444 aa overlap). Contains Pfam match to entry PF00069 FT pkinase, Eukaryotic protein kinase domain, PS00108 FT Serine/Threonine protein kinases active-site signature and FT PS00107 Protein kinases ATP-binding region signature" FT /db_xref="GOA:Q9S2A6" FT /db_xref="HSSP:1O6Y" FT /db_xref="InterPro:IPR017441" FT /db_xref="UniProtKB/TrEMBL:Q9S2A6" FT /protein_id="CAB50939.1" FT /translation="MSGEPDGERVIAGRYRLLSPLGEGGMGTVWRARDEVLRREVAVKE FT VRAPAGLSQPDVGRMYARLEREAWAAARISHPNVVTVYDVATDGGRPWIVMELVRGLSL FT ADLLDAEGPLEPRRAALIGAEVLAALRAAHAAGVLHRDVKPANVLLANDGRVVLTDFGI FT ARVEGSEALTMTGEVVGSPEFLAPERALGRTPGAASDLWSLGVLLYATVEGVSPFRQGT FT PLSTLRAIVDEAVPPPRRAGALGPVVEGLLRKDPAERLPAEEAERALRLVGAGGAPPGR FT GPRTGAPPSGAFAPTVVAAHPGPPTAPTPPMPVPAAGDTSAAGAPGAPGGRDRRARAVL FT LVGLAVLVLALAGLTYSLLDRSDGGGGTEGSGGSPGPGATSAATSGGAGEPSPPASSGT FT DGGQSGPAAQSVEVTVVGSRTHYSGACPPPHDRAPAFTATFTVGRLPAEVGYRWVTADG FT SVSDPGWRTLSFPSGGERSRQDGVVVTTHDDTGAFESAVRVEVRSPVRATSDAVAFSVT FT CGTGTETETGTGTPSGGASHSSSPSAPSSSPSA" FT misc_feature 24880..25632 FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 205.40, E-value 8.7e-58" FT misc_feature 24898..24969 FT /note="PS00107 Protein kinases ATP-binding region FT signature" FT misc_feature 25249..25287 FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT CDS complement(26493..27299) FT /transl_table=11 FT /gene="SCO1725" FT /gene_synonym="SCI11.14c" FT /product="putative secreted hydrolase" FT /note="SCI11.14c, possible secreted hydrolase, len: 268 aa; FT similar to TR:Q59837 (EMBL:X92765), estA, Streptomyces FT diastatochromogenes esterase A (326 aa), fasta scores; opt: FT 147 z-score: 171.2 E(): 0.033, 26.8% identity in 314 aa FT overlap. The difference in length is accounted for by FT internal deletions in this protein, relative to TR:Q59837. FT The putative active-site serine motif GDSYT in the FT S.diastatochromogenes enzyme is conserved in this protein. FT Contains a probable N-terminal signal sequence" FT /db_xref="GOA:Q9S2A5" FT /db_xref="InterPro:IPR013831" FT /db_xref="UniProtKB/TrEMBL:Q9S2A5" FT /protein_id="CAB50940.1" FT /translation="MRRFRLVGFLSSLVLAAGAALTGAATAQAAQPAAADGYVALGDSY FT SSGVGAGSYISSSGDCKRSTKAHPYLWAAAHSPSTFDFTACSGARTGDVLSGQLGPLSS FT GTGLVSISIGGNDAGFADTMTTCVLQSESSCLSRIATAEAYVDSTLPGKLDGVYSAISD FT KAPNAHVVVIGYPRFYKLGTTCIGLSETKRTAINKASDHLNTVLAQRAAAHGFTFGDVR FT TTFTGHELCSGSPWLHSVNWLNIGESYHPTAAGQSGGYLPVLNGAA" FT CDS 27485..28579 FT /transl_table=11 FT /gene="SCO1726" FT /gene_synonym="SCI11.15" FT /product="putative ATPase" FT /note="SCI11.15, possible ATPase, len: 364 aa; unknown FT function, very weak similarity to eukaryotic putative FT ATPases e.g. TR:P78787 (EMBL:D89136) Schizosaccharomyces FT pombe putative ATPase (partial CDS) (419 aa), fasta scores; FT opt: 184 z-score: 216.6 E(): 9.9e-05, 26.5% identity in 309 FT aa overlap and to part of SW:AFG2_YEAST (EMBL:L14615), FT Agf2, Saccharomyces cerevisiae putative ATPase essential FT for viability (780 aa) (29.9% identity in 137 aa overlap). FT Contains weak Pfam match to entry PF00004 AAA, ATPases FT associated with various cellular activities (AAA) and FT PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9S2A4" FT /db_xref="InterPro:IPR003959" FT /db_xref="UniProtKB/TrEMBL:Q9S2A4" FT /protein_id="CAB50941.1" FT /translation="MSVNPHEALPIRLNVDDSDSPSDVVDALFLGRFATGEQPYSHAAN FT IDRVRSGATLLPPGARVLRIARDDDRSATLAEGDGWTLLISRWSRGADVTVTATSADLA FT EKVLGEATDGAADEPEPQPENVTMGFWYVSPRRGPHRTTRQIAAGTWDEVRANYTAPVA FT DAMDGLMKTTPEDIAGRLLLLHGPPGTGKTSALRTLARSWRDWCQVDCVLDPERLFSDV FT GYLMDIAIGEEDAAGKGRWRLLLLEDCDELIRGEAKHTAGQALSRLLNLTDGLLGQGRN FT VLVGVTTNEDLERLHPAVVRPGRCLARIEVGPLSRREAVDWLGTEEGVGREGATLAELY FT ALRRGTSPTALPEPRAGAEAGLYL" FT misc_feature 28025..28540 FT /note="Pfam match to entry PF00004 AAA, ATPases associated FT with various cellular activities (AAA), score -8.90, FT E-value 0.00013" FT misc_feature 28040..28063 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 28614..29381 FT /transl_table=11 FT /gene="SCO1727" FT /gene_synonym="SCI11.16" FT /product="conserved hypothetical protein" FT /note="SCI11.16, conserved hypothetical protein, len: 255 FT aa; unknown function, similar hypothetical proteins e.g. FT TR:O67070 (EMBL:AE000714) Aquifex aeolicus hypothetical FT protein (252 aa), fasta scores; opt: 459 z-score: 574.9 FT E(): 1.1e-24, 33.0% identity in 230 aa overlap and the FT N-terminal half of SW:YECE_ECOLI (EMBL:AE000280) FT Escherichia coli hypothetical protein (272 aa) (29.0% FT identity in 155 aa overlap). Similar to TR:Q9ZBF5 FT (EMBL:AL035206) S. coelicolor hypothetical protein (292 aa) FT (32.2% identity in 283 aa overlap)" FT /db_xref="InterPro:IPR002763" FT /db_xref="UniProtKB/TrEMBL:Q9S2A3" FT /protein_id="CAB50942.1" FT /translation="MTLFVGTSGWQYRDWRESFYPPGLPVRRWLEHYAAAFATVEINNA FT FYRLPARETFTAWRDRVPPDFTVAVKASRYLTHIKRLRDPAEPVDRLMTHAAGLGDRLG FT PVLLQLPPTLRADPDLLDACLACFPPGTRVAVEPRHESWWTAETREVLVARRAALCWAD FT VRARPVTPLWRTTDWGYVRFHEGRAAAWPHYGRRSLVTWIDRITAAWPHTSDVYTYFNN FT DPNTAAVQDAATFAQSARTSALTVTRTPSGARG" FT CDS complement(29462..29866) FT /transl_table=11 FT /gene="SCO1728" FT /gene_synonym="SCI11.17c" FT /product="putative gntR-family transcriptional regulator" FT /note="SCI11.17c, possible gntR-family transcriptional FT regulator, len: 134 aa; weakly similar to the N-terminal FT half of SW:HUTC_PSEPU (EMBL:M33922), HutC, Pseudomonas FT putida histidine utilization repressor (248 aa), fasta FT scores; opt: 164 z-score: 202.7 E(): 0.00059, 33.9% FT identity in 109 aa overlap. Similar to many putative FT transcriptional regulators e.g. SCGD3.13 (EMBL:AL096822) FT S.coelicolor probable gntR-family transcriptional regulator FT (115 aa) (32.4% identity in 111 aa overlap) and to FT TR:O06550 (EMBL:Z95584) Mycobacterium tuberculosis FT hypothetical protein (121 aa) (50.0% identity in 106 aa FT overlap). Contains probable helix-turn-helix motif at aa FT 106-127 (Score 1082, +2.87 SD). Contains Pfam match to FT entry PF00392 gntR, Bacterial regulatory proteins, gntR FT family" FT /db_xref="GOA:Q9S2A2" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9S2A2" FT /protein_id="CAB50943.1" FT /translation="MPLIFTGIRDNRRVTLKIHVDDGAPPYEQVRAQISEQARSGALPV FT GYRLPTVRGLAESLGLAANTVAKAYRALEADGVIETRGRNGTFVAAAGSAAQREVAAAA FT QGYAERARRLGVSEEDASGAVRDALRAAYG" FT misc_feature complement(29600..29779) FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 56.00, E-value FT 9.1e-16" FT CDS 29899..30825 FT /transl_table=11 FT /gene="SCO1729" FT /gene_synonym="SCI11.18" FT /product="hypothetical protein" FT /note="SCI11.18, hypothetical protein, len: 308 aa; unknown FT function, N-terminal half weakly similar to parts of other FT hypothetical proteins e.g. TR:O32075 (EMBL:Z99119) Bacillus FT subtilis hypothetical protein (173 aa), fasta scores; opt: FT 148 z-score: 187.8 E(): 0.004, 28.0% identity in 168 aa FT overlap. Weakly similar to TR:Q9ZBG7 (EMBL:AL035206) FT S.coelicolor hypothetical protein (319 aa) (30.1% identity FT in 272 aa overlap). Contains weak Pfam match to entry FT PF00583 Acetyltransf, Acetyltransferase (GNAT) family" FT /db_xref="GOA:Q9S2A1" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9S2A1" FT /protein_id="CAB50944.1" FT /translation="MTVLVRDLRSDDPADVAAFAQVRHLAVPFILWTPEAVVHRLVHTH FT PDARSRSLVAEEDGEVIGTAQLGLAHDSPEPGQAYLNVYVHPERFRRGAGGLLVRTAEE FT HLTGEGARKLYSWVLDGPAHLAFAERHGYERRRASHFLRLDLANAALPPLGALPPGVEL FT RTAADYADDPRPVFELDAATVADEPSDVAVEFTDYEAWLAETWRHPLLDRELTTVVVVD FT GRPAAFSVAHTDGTRYATAMTGTVRARRGRGLAKLAKTASLRRARAAGYTEALTGNDTD FT NGPMLAVNKWLGYEICATEVRHVRELG" FT misc_feature 29920..30300 FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 26.70, E-value FT 0.00055" FT RBS 30795..30799 FT /note="possible RBS" FT CDS 30806..31306 FT /transl_table=11 FT /gene="SCO1730" FT /gene_synonym="SCI11.19" FT /product="hypothetical protein" FT /note="SCI11.19, hypothetical protein, len: 166 aa; unknown FT function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Overlaps the upstream CDS by 6 codons" FT /db_xref="InterPro:IPR007295" FT /db_xref="UniProtKB/TrEMBL:Q9S2A0" FT /protein_id="CAB50945.1" FT /translation="MSVNSAEPPIEVDVILVKAGRTKIRYPAGLLHDDGTRLAVRAPWA FT GDGVRDFGFVRFEAGDVFTEYYWRDRWYSVKEVRTAAGVLKGWYCDITRPAVRTGTELV FT VEDLDLDLWRSADGADVRRLDEDEFAESGLTDRDPEAAAAAVAALEELERLARGDGFTG FT LLE" FT CDS complement(31320..31937) FT /transl_table=11 FT /gene="SCO1731" FT /gene_synonym="SCI11.20c" FT /product="conserved hypothetical protein" FT /note="SCI11.20c, hypothetical protein, len: 205 aa; weakly FT similar to parts of many hypothetical proteins, many of FT which resemble methyltransferases e.g. TR:Q48938 FT (EMBL:X93084) Methanosarcina barkeri ORF3 from molybdenum FT formylmethanofuran dehydrogenase cluster (262 aa), fasta FT scores; opt: 445 z-score: 518.9 E(): 1.4e-21, 37.8% FT identity in 193 aa overlap. Weak similarity to many others FT from S.coelicolor e.g. TR:Q9ZC03 (EMBL:AL033505) FT S.coelicolor hypothetical protein (273 aa) (35.2% identity FT in 142 aa overlap)" FT /db_xref="GOA:Q9S299" FT /db_xref="HSSP:1G6Q" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:Q9S299" FT /protein_id="CAB50946.1" FT /translation="MSGNSDEATAPGADWDALAASFDDEPDHGLRDAEVRRAWAARLAS FT WLPAPPGDVLDLGCGTGSLSLLAAEQGHRVTGVDLSPAMVELARTKLAGRDAVFLTGDA FT AAPPVGEQRFDAVLVRHVLWTLPDPGRALRHWRQLLRPGGRLVLVEGVWGSVSPVGIPA FT DRVTALLGPLTGQARVERLSDDPSLWGREVADERYAVVATYG" FT RBS 32078..32083 FT /note="possible RBS" FT CDS 32089..32223 FT /transl_table=11 FT /gene="SCO1732" FT /gene_synonym="SCI11.21" FT /product="hypothetical protein" FT /note="SCI11.21, hypothetical protein, len: 44 aa; unknown FT function, possible CDS suggested by GC frameplot and the FT presence of a possible RBS" FT /db_xref="UniProtKB/TrEMBL:Q9S298" FT /protein_id="CAB50947.1" FT /translation="MRRLTVQKPLKKTDARRVREEIDERPSGRPEVRKDIARTWWPES" FT CDS complement(32249..32719) FT /transl_table=11 FT /gene="SCO1733" FT /gene_synonym="SCI11.22c" FT /product="putative acetyltransferase" FT /note="SCI11.22c, possible acetyltransferase, len: 156 aa; FT unknown function, weakly similar to TR:Q51670 (EMBL:U34346) FT Paracoccus denitrificans hypothetical protein (173 aa), FT fasta scores; opt: 144 z-score: 184.8 E(): 0.0058, 28.9% FT identity in 149 aa overlap. Very weak similarity to some FT acetyltransferases e.g. SW:IAAT_AZOBR (EMBL:X57853) FT Azospirillum brasilense IAA acetyltransferase (153 aa) FT (26.1% identity in 111 aa overlap). Contains Pfam match to FT entry PF00583 Acetyltransf, Acetyltransferase (GNAT) FT family" FT /db_xref="GOA:Q9S297" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q9S297" FT /protein_id="CAB50948.1" FT /translation="MERERIRPATAADVPAVQAVTDAAYLPYVERIGVVPQPMEADHAA FT DVAAGKVFVTDEPGTGRAGPVGLVVVEAHADHLFLDSVAVHPDAHGRGVGRRLLRFVDA FT HARALGLPEVRLYTNAMMRENQEIYPRYGYEVVERRVDGPYDRVHYRKRLLL" FT misc_feature complement(32315..32704) FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 44.20, E-value FT 2.9e-09" FT CDS 32898..33968 FT /transl_table=11 FT /gene="SCO1734" FT /gene_synonym="SCI11.23" FT /product="putative secreted cellulose-binding protein" FT /note="SCI11.23, possible secreted cellulose-binding FT protein, len: 356 aa; similar cellulose-binding proteins FT e.g. TR:O07862 (EMBL:U51222) Streptomyces halstedii FT cellulose-binding protein (364 aa), fasta scores; opt: 584 FT z-score: 557.4 E(): 1e-23, 35.7% identity in 305 aa FT overlap. Weaker similarity to chitin-binding proteins e.g. FT TR:O87962 (EMBL:Y14315) Streptomyces reticuli FT chitin-binding protein (201 aa) (32.7% identity in 214 aa FT overlap) secreted when co-cultivated with chitin-containing FT fungi. Weak similarity to TR:O86614 (EMBL:AL031155) FT S.coelicolor possible secreted chitinase (252 aa) (28.9% FT identity in 266 aa overlap). Contains a probable N-terminal FT signal sequence,a possible hydrophobic membrane spanning FT region at the C-terminal domain and 6x G(D/S) repeats FT starting at codon 215" FT /db_xref="GOA:Q9S296" FT /db_xref="InterPro:IPR019931" FT /db_xref="UniProtKB/TrEMBL:Q9S296" FT /protein_id="CAB50949.1" FT /translation="MPAPSASRRAAAVAVAGLAPLALTTLAAAPASAHGSMGDPVSRVS FT QCHAEGPENPKSAACRAAVAAGGTQALYDWNGIRIGNAAGKHQELIPDGRLCSANDPAF FT KGLDLARADWPATGVSSGSYTFKYRVTAPHKGTFKVYLTKPGYDPSKPLGWGDLDLSAP FT VATSTDPVASGGFYTFSGTLPERSGKHLLYAVWQRSDSPEAFYSCSDVTFGGDGDGDGD FT GGSGSGAATGDDTASGDAEAGAAPAPEASAPSEEQLAAAAEKSTIEHHGHGDQDAATTT FT DPTDPAAAPEEAPGTAAEPHQVKAAGGGTENLAETGGDSTTPYIAVGGAAALALGAAVL FT FASVRRRATTGGRHGH" FT repeat_region 33540..33581 FT /note="6x degenerate 6 bp repeats" FT CDS complement(34076..34948) FT /transl_table=11 FT /gene="SCO1735" FT /gene_synonym="SCI11.24c" FT /product="putative secreted lipase" FT /note="SCI11.24c, probable secreted lipase, len: 290 aa; FT similar to many lipases e.g. TR:O33969 (EMBL:U80063), lipA, FT Streptomyces cinnamoneus lipase (275 aa), fasta scores; FT opt: 575 z-score: 653.1 E(): 4.8e-29, 47.6% identity in 254 FT aa overlap. Contains probable N-terminal signal sequence" FT /db_xref="HSSP:1ISP" FT /db_xref="InterPro:IPR002918" FT /db_xref="UniProtKB/TrEMBL:Q9S295" FT /protein_id="CAB50950.1" FT /translation="MLPWSRVLRPLAALLLAAAVALVPATAATAAPTADARPGSGWNDY FT TCKPSAAHPRPVVLVHGTFGNSVDNWLGLAPYLKNRGYCVFSLDYGQLPGVPLFHGLGP FT VEKSAEQLAAHVDKVLAATGATETDLVGHSQGGMMPRYYLKFLGGAAEVNALVGIAPSN FT HGTTLSGLTRLLPYFPGAEDLLNEHTPALADQVVGSDVLTRLNAGGDTVPGVRYTVLAT FT KYDEVVTPYRGQFLDGPGVRNVLLQDLCPLDLSEHLAIGLFDRIAFHEVTNALDPAHAT FT PTTCASVFG" FT CDS complement(35128..35574) FT /transl_table=11 FT /gene="SCO1736" FT /gene_synonym="SCI11.25c" FT /product="putative marR-family transcriptional regulator" FT /note="SCI11.25c, possible marR-family transcriptional FT regulator, len: 148 aa; weakly similar to hypothetical FT proteins e.g. SW:YW06_MYCTU (EMBL:Z74025) Mycobacterium FT tuberculosis hypothetical protein (143 aa), fasta scores; FT opt: 159 z-score: 204.1 E(): 0.00049, 31.9% identity in 135 FT aa overlap. An alternative start codon is present at codon FT 7. Contains probable helix-turn-helix motif at aa 53-74 FT (Score 1261, +3.48 SD). Contains Pfam match to entry FT PF01047 MarR, MarR family. Contains possible N-terminal FT region signal peptide sequence" FT /db_xref="GOA:Q9S294" FT /db_xref="HSSP:1JGS" FT /db_xref="InterPro:IPR000835" FT /db_xref="UniProtKB/TrEMBL:Q9S294" FT /protein_id="CAB50951.1" FT /translation="MQNSDAMALTAALLAAAGGLTQRINEGVVARGFEGVRPAHGFAFA FT RLAPDGATVTDLAVHLGVTKQAASQLVDELVRKGYAERRPHPVDARARLVVLTEAGWAC FT TRAAEAAAAEAVGAWADVLGEDGVRALLDGLLRVAPNGPLRPAW" FT misc_feature complement(35161..35469) FT /note="Pfam match to entry PF01047 MarR, MarR family, score FT 25.70, E-value 8.8e-05" FT CDS 35685..36059 FT /transl_table=11 FT /gene="SCO1737" FT /gene_synonym="SCI11.26" FT /product="hypothetical protein" FT /note="SCI11.26, hypothetical protein, len: 124 aa; unknown FT function, similar to TR:O86372 (EMBL:AL022003) FT Mycobacterium tuberculosis hypothetical protein (116 aa), FT fasta scores; opt: 129 z-score: 177.0 E(): 0.016, 34.7% FT identity in 98 aa overlap" FT /db_xref="InterPro:IPR014710" FT /db_xref="UniProtKB/TrEMBL:Q9S293" FT /protein_id="CAB50952.1" FT /translation="MPVVRSSEGVTHEIHGARFVSYASPRVGSRELCAWRGEIPAGTKA FT PAHTVDREEVFHLLTGELLITLDGRTERVTAGDTVIIGSGATLAVENPTDRTATSWVTT FT SVGLTAELADGTRITPPWAN" FT CDS complement(36072..37040) FT /transl_table=11 FT /gene="SCO1738" FT /gene_synonym="SCI11.27c" FT /product="conserved hypothetical protein" FT /note="SCI11.27c, conserved hypothetical protein, len: 322 FT aa; similar to many hypothetical proteins related to the FT impB/mucB/samB family e.g. TR:Q10787 (EMBL:Z74020) FT Mycobacterium tuberculosis hypothetical protein (463 aa), FT fasta scores; opt: 330 z-score: 372.5 E(): 2.1e-13, 29.5% FT identity in 281 aa overlap" FT /db_xref="GOA:Q9S292" FT /db_xref="InterPro:IPR017963" FT /db_xref="UniProtKB/TrEMBL:Q9S292" FT /protein_id="CAB50953.1" FT /translation="MTILCVRFQLPPTREAALPELLGLLEEFTPVVEALPPDGALADLR FT GAERYFGRDAVALASVIRVRALALHGVDCVIGAGPGPMLARMALRDARPGLTRAVPGGE FT ERAFLDGKPVAALPGVGTATARTLCEYGLDTLGRVAAAPLSTLQRLVGARTGRELHEKA FT QGVDRGRVVPNGVSRSLAADRPFDRDELDPDRHRRALLSAAGDLGARLRAVDKVCRTLT FT LTVRYADRSATTRSRTLREPTAHSAALTRTAYDLYEALGLQRARVRSIALRAESLTSAE FT HASHQLTFDPVDEKVRRIEEVADRARAKFGPRAVMPGSLAA" FT CDS complement(37037..40594) FT /transl_table=11 FT /gene="SCO1739" FT /gene_synonym="SCI11.28c" FT /product="putative DNA polymerase III, alpha chain" FT /note="SCI11.28c, probable DNA polymerase III, alpha chain, FT len: 1185 aa; similar to many e.g. SW:DP3A_ECOLI FT (EMBL:M19334), dnaE, Escherichia coli DNA polymerase III, FT alpha chain (1160 aa), fasta scores; opt: 1177 z-score: FT 1220.7 E(): 0, 28.4% identity in 1135 aa overlap" FT /db_xref="GOA:Q9S291" FT /db_xref="InterPro:IPR004805" FT /db_xref="UniProtKB/TrEMBL:Q9S291" FT /protein_id="CAB50954.1" FT /translation="MPGFTHLHTVSGFSARYGASHPERLAERAFERGMDALALTDRDTL FT AGTVRFAKACAKAGVRPLFGAELAVAAPESAAADRTETSVRRDRRRAPVRGGAFVDESA FT PRVTFLARDGARGWADLCRLVSAAHTAEGSPLLSWPDNHADGLTVLLGPDSDVGRALAA FT GRPDRAARLLVPWREVYGDALRLEAVWHGRTGIGPGSLRLAARTVGFAAEQGVRPVLSN FT AVRYADPGQGEVADVLDAARRLVPIGATKELDSGEAWLKDAGAMRHAAERIVESAGFRR FT DTAHRLLEQTRATAAECLVDPEDDLGMGAVHFPEPHLVGAGRRTAQRALASRAAAGMVR FT RGYDRRRDHREYWERMHHELDIIAHHGFASYFLTVAQVVDDVRHMGIRVAARGSGAGSL FT VNHLLGIAHADPVEHGLLMERFLSKERVVLPDIDIDVESARRLEVYRAIIGRFGTERVA FT TVAMPETYRVRHAIRDVGAALSMDPAEIDRVAKSFPHIRARDARAALEELPELKELAGE FT SRRDGGGRYGRLWELVEGLDALPRGVAMHPCGVLLSDASLLSRTPVVPTSGEGLPMAQF FT DKDDVEDLGLLKLDVLGVRMQSAMAHAVAEVKRATGTEVDLDAVPEGDPATYRMIRSAE FT TLGCFQIESPGQRDLVGRLQPATFHDLVVDISLFRPGPVAADMVRPFIEARHGRAPVRH FT PHEDLAEPLAGTYGVVVFHEQIIDIVAIMTGCGRGEADRVRRGLSDPESQGRIKVWFAQ FT HATANGYDAETIQRTWEIVEAFGSYGFCKAHAVAFAVPTYQSAWLKAHHPAAFYAGLLT FT HDPGMYPKRLLLADARRRGVPILPLDVNESGVAHRIELVSESGSRKPATWGLRLALSDV FT HGISEAEAERIATGQPYASLLDFWERARPSRPLAGRLAQVGALDAFGANRRDLQLHLTE FT LHRGARGGRGDQLPLTGGRKTASAGLPDLTSEEKLSAELGVLSMDASRNLMDDHRTFLR FT ELGVVSAKRLREARHGETVLVAGAKAATQTPPVRSGRRVIFSTLDDGSGLVDLAFFDDS FT HDACAHTVFHSWLLLVRGVVQRRGPRSLSVVGSAAWNLADLLEIRREEGLEGVAARLAA FT AGGSQEGDAPGGGPARRRLAGSDGRPAPAGSAAQDPMEQRKIRMSTGYEMHPWADLRPA FT GEGPAVGRKLWHQSPGSAG" FT CDS 40768..41832 FT /transl_table=11 FT /gene="SCO1740" FT /gene_synonym="SCI11.29" FT /product="putative membrane protein" FT /note="SCI11.29, possible membrane protein, len: 354 aa; FT unknown function, weakly similar to TR:O07424 (EMBL:Z97050) FT Mycobacterium tuberculosis possible membrane protein (452 FT aa), fasta scores; opt: 190 z-score: 202.3 E(): 0.00062, FT 25.9% identity in 409 aa overlap. Contains hydrophobic, FT possible membrane-spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9S290" FT /protein_id="CAB50955.1" FT /translation="MSHTPGPGTRSGSFLGEVRDAVTPRATLLVLGVIALQLLFIASYV FT GALHDPRPKDVPFGVVAPGAAAGQTVDRLEGLPGSPLDPRTVADEAAARRQIMNREIDG FT ALVLDPGGRQDTLLVASGGGTVLATTLEGIVGKAEQTERRTVRVVDVAPASRHDFDGLS FT SFYLIVGWCVGGYLCASILAISTGARPANPRRAAIRLIVMALVAIVGGLGGAVIIGPIL FT GALPGGVLDLWGLGALITFAVGAATLALQGVFGIVGIGLAILLVVIAGNPSAGGAFPLP FT LLPPFWKAIGPALPPGAGTWAARSIAYFKGNDVTASLLVLWAWAVAGTVITMLAAVLPR FT RGRQETELPPAPAG" FT CDS complement(41947..43029) FT /transl_table=11 FT /gene="SCO1741" FT /gene_synonym="SCI11.30c" FT /product="putative secreted serine protease" FT /note="SCI11.30c, probable secreted serine protease, len: FT 360 aa; highly similar to many serine proteases e.g. FT SW:PRTD_STRGR (EMBL:L29019), sprD, Streptomyces griseus FT serine protease D precursor (392 aa), fasta scores; opt: FT 1703 z-score: 1655.9 E(): 0, 67.1% identity in 392 aa FT overlap. Similar to S.coelicolor SCI11.35c, sal, secreted FT serine protease (300 aa) (52.2% identity in 278 aa FT overlap). Contains a probable N-terminal signal sequence. FT Contains probable coiled-coil from 84 to 119 (36 residues) FT (Max score: 1.468, probability 0.91). Contains Pfam match FT to entry PF00089 trypsin, Trypsin, PS00134 Serine FT proteases, trypsin family, histidine active site and FT PS00135 Serine proteases, trypsin family, serine active FT site" FT /db_xref="GOA:Q9S289" FT /db_xref="HSSP:2SFA" FT /db_xref="InterPro:IPR018114" FT /db_xref="UniProtKB/TrEMBL:Q9S289" FT /protein_id="CAB50956.1" FT /translation="MKHRRIPRRRVAVVGAGITALVAAGVTFQTANASEAPKTAAPETL FT SVSAAGELASTLLGDLGADAAGTYYDAQAKSLVVNVLDQSAAQTVEEAGAKARVVENSL FT ADLKSARTALTKDATIPGTSWATDPTTNKVVVTADRTVSEAELAKLTKVVDGLGAKAEL FT KRTKGEYKPFVAGGDAITGGGGRCSLGFNVTKGGEPYFITAGHCTESISTWSDSSGNVI FT GENAASSFPDNDYGLVKYTADVDHPSEVNLYNGSSQAISGAAEATVGMQVTRSGSTTQV FT HDGTVTGLDATVNYGNGDIVNGLIQTDVCAEPGDSGGSLFSGDQAIGLTSGGSGDCTSG FT GETFFQPVTEALSATGTQIG" FT misc_feature complement(41965..42510) FT /note="Pfam match to entry PF00089 trypsin, Trypsin, score FT 4.90, E-value 5.1e-05" FT repeat_region complement(41974..42049) FT /note="repeat 3; degenerate 76 bp direct repeat" FT misc_feature complement(42067..42102) FT /note="PS00135 Serine proteases, trypsin family, serine FT active site" FT repeat_region complement(42069..42205) FT /note="repeat 4; degenerate 137 bp direct repeat" FT repeat_region complement(42306..42375) FT /note="repeat 5; degenerate 70 bp direct repeat" FT repeat_region complement(42404..42450) FT /note="repeat 6; degenerate 47 bp direct repeat" FT misc_feature complement(42409..42426) FT /note="PS00134 Serine proteases, trypsin family, histidine FT active site" FT repeat_region complement(42452..42512) FT /note="repeat 7; degenerate 61 bp direct repeat" FT repeat_region complement(42583..42623) FT /note="repeat 8; degenerate 41 bp direct repeat" FT RBS complement(43037..43042) FT /note="possible RBS" FT CDS 43299..44219 FT /transl_table=11 FT /gene="SCO1742" FT /gene_synonym="SCI11.31" FT /product="putative ABC-transporter ATP-binding protein" FT /note="SCI11.31, probable ABC-transporter ATP-binding FT protein, len: 319 aa; similar to SW:BCRA_BACLI FT (EMBL:L20573), bcrA, Bacillus licheniformis bacitracin FT transport ATP-binding protein (306 aa), fasta scores; opt: FT 561 z-score: 595.7 E(): 7.5e-26, 36.2% identity in 298 aa FT overlap and to many putative ABC-transporter ATP-binding FT proteins. Similar to others from S.coelicolor e.g. SCE8.17C FT (EMBL:AL035654) S.coelicolor probable ABC transporter FT ATP-binding protein (317 aa) (45.9% identity in 296 aa FT overlap). Contains Pfam match to entry PF00005 ABC_tran, FT ABC transporter and PS00017 ATP/GTP-binding site motif A FT (P-loop)" FT /db_xref="GOA:Q9S288" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9S288" FT /protein_id="CAB50957.1" FT /translation="MTSSRGAGDPAAIRVEGLTKRYGRATAVDDLSFTVGTGRVTGFFG FT PNGAGKTTALKAVVGLARPTAGRAFVRGTPVAALKPDARLLGVHIEPCGAHPGRTGRAH FT LRSLAALAGLPRRRVGEVLELVGLEEAARGRVGKYSMGMRQRLGLAAALLGDPEILVLD FT EPVNGLDPQGIRWLRTLLRERAAKGGTVLLSSHMLGEAAQTVDDVVVINRGRLVHEGAI FT RDLERSGERVVAVRTAEAERLSELVTAAGGRTKTDDGGRLLVEGLDVTEVARLAHRDGV FT LVEEITERTASLEDAFFGLTGGADR" FT misc_feature 43410..43940 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 147.30, E-value 2.7e-40" FT repeat_region 43429..43459 FT /note="repeat 1; degenerate 31 bp direct repeat" FT misc_feature 43431..43454 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT repeat_region 43650..43943 FT /note="repeat 2; highly degenerate 294 bp direct repeat" FT CDS 44216..44935 FT /transl_table=11 FT /gene="SCO1743" FT /gene_synonym="SCI11.32" FT /product="putative ABC-transporter transmembrane protein" FT /note="SCI11.32, possible ABC-transporter transmembrane FT protein, len: 239 aa; weakly similar to putative FT ABC-transporter protein from S.coelicolor TR:O69995 FT (EMBL:AL022374) S.coelicolor probable ABC transporter (744 FT aa), fasta scores; opt: 197 z-score: 224.6 E(): 3.5e-05, FT 35.4% identity in 212 aa overlap. Contains hydrophobic, FT possible membrane-spanning regions. May be associated with FT the adjacent putative ABC-transporter ATP-binding protein" FT /db_xref="GOA:Q9S287" FT /db_xref="UniProtKB/TrEMBL:Q9S287" FT /protein_id="CAB50958.1" FT /translation="MSRLLRGELIKTVTTRTVLGFAVGTVAFAALNALVVAAWSGTLDE FT VAEKEEALSAMPVLLLLWGLVGAAGEYRHRTAAPAALVGRRGRGVVLSARIAAYALTGL FT LLGALTTTVSVGLALPLLSDQPGPDLTSADVGAVVAGNLVAFVLSTILGAALGALIRSP FT VLGVVVLLVVNFAVVPLLSGVWEAGVNLTPFGAAGILSRMTHHTTLSVVSAGWVLAAWT FT VAVTLVAVVVERRRDLA" FT CDS 44932..46098 FT /transl_table=11 FT /gene="SCO1744" FT /gene_synonym="SCI11.33" FT /product="putative two-component system sensor kinase" FT /note="SCI11.33, possible two-component system sensor FT kinase, len: 388 aa; similar to may putative sensor kinases FT e.g. to the N-terminus of TR:Q53893 (EMBL:AL035654), AbsA1, FT S.coelicolor putative two-component system sensor kinase FT involved in global regulation of antibiotic synthesis (571 FT aa), fasta scores; opt: 361 z-score: 391.6 E(): 1.8e-14, FT 31.6% identity in 364 aa overlap. The C-terminus is similar FT to part of SW:NARX_ECOLI (EMBL:X13360), NarX, NarR, FT Escherichia coli nitrate/nitrite sensor protein (598 aa) FT (30.7% identity in 218 aa overlap). Contains hydrophobic, FT possible membrane-spanning regions. Contains probable FT coiled-coil from 157 to 189 (33 residues) (Max score: FT 1.493, probability 0.94)" FT /db_xref="GOA:Q9S286" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9S286" FT /protein_id="CAB50959.1" FT /translation="MNDLFGRARAAYDLLVARRSALFDLVLAVITTGVEIGQLFDGGTP FT VVVIPAAVIPVGVIPVVVTVLTGSALLLRRRAPLTVLVTACAGAAVLVPLGYSPGGAPV FT VVALASLADLRDRRVSVAALVPTALFLLLASISSLPVPVGAWALGSYLQTRRRYTRALE FT DRAATLERERAQLDQLAAQRERTAIARELHDIVAHSVTVMLIGVRGARDVLPTDPGVAA FT ETLEPVEVNAEQSLAELRRILGLLRTPDNGAQWRPQPSLGQLPELVSGYRTAGMPVQLE FT FTGEARPLAGGLELSAYRIVEEALTNVLKHTDPTRVTVTLHYGRTWLDVTVEDDGGGGG FT PAPSGAGHGILGMRERAAVTGGSLDARRTADGFVVTARLPVEDAGDAA" FT CDS 46095..46760 FT /transl_table=11 FT /gene="SCO1745" FT /gene_synonym="SCI11.34" FT /product="putative two-component system response regulator" FT /note="SCI11.34, probable two-component system response FT regulator, len: 221 aa; similar to SW:NARL_ECOLI FT (EMBL:X13360), NarL, Escherichia coli nitrate/nitrite FT response regulator protein (216 aa), fasta scores; opt: 482 FT z-score: 568.4 E(): 2.5e-24, 38.9% identity in 211 aa FT overlap and TR:Q53894 (EMBL:AL035654), AbsA2, S.coelicolor FT putative two-component system response regulator (222 aa) FT (43.1% identity in 218 aa overlap). Contains probable FT helix-turn-helix motif at aa 171-192 (Score 1021, +2.66 FT SD). Contains Pfam matches to entry PF00072 response_reg, FT Response regulator receiver domain and to entry PF00196 FT GerE, Bacterial regulatory proteins, luxR family. Contains FT PS00622 Bacterial regulatory proteins, luxR family FT signature" FT /db_xref="GOA:Q9S285" FT /db_xref="HSSP:1RNL" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9S285" FT /protein_id="CAB50960.1" FT /translation="MTIRLLIVDDQELIRTGFRLFLQTQNDLEVVGEADDGHGALAQAA FT ALRPDVVLMDIRMPRMDGVEATSRLTASDSPPRVLILTTYDLDEYVFGALRAGASGFLL FT KDASRDRLLEAIRVVHAGEALLSPSITRRLIEDYATRAAPVRPREAVLAGLTPREREIL FT LLVARGLSNPEIAARLVVTEATVKSHVGSMFAKLHLRDRAQAVVFAYENAIVLPGGTG" FT misc_feature 46101..46442 FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 139.40, E-value 6.6e-38" FT misc_feature 46548..46745 FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 74.50, E-value FT 2.3e-18" FT misc_feature 46599..46682 FT /note="PS00622 Bacterial regulatory proteins, luxR family FT signature" FT stem_loop 46748..46808 FT /note="stem, 26/30 (86%) matches, 1 gaps; loop, 0 bp" FT CDS complement(46827..47729) FT /transl_table=11 FT /gene="SCO1746" FT /gene_synonym="SCI11.35c" FT /gene_synonym="sal" FT /product="secreted serine protease" FT /note="SCI11.35c, sal, secreted serine protease, len: 300 FT aa; highly similar to extracellular serine proteases from FT Streptomyces spp. Identical to TR:Q54392 (EMBL:L44109), FT Sal, Streptomyces lividans chymotrypsin-like serine FT protease (300 aa), fasta scores; opt: 1919 z-score: 1861.1 FT E(): 0, 99.7% identity in 300 aa overlap. Similar to FT SCI11.30c S.coelicolor probable secreted serine protease FT (360 aa) (52.2% identity in 278 aa overlap). Contains FT probable N-terminal signal sequence. Contains Pfam match to FT entry PF00089 trypsin, Trypsin, PS00134 Serine proteases, FT trypsin family, histidine active site and PS00135 Serine FT proteases, trypsin family, serine active site" FT /db_xref="GOA:Q7AKQ0" FT /db_xref="InterPro:IPR018114" FT /db_xref="UniProtKB/TrEMBL:Q7AKQ0" FT /protein_id="CAB50961.1" FT /translation="MRIKRTTPRSGITRRTRLIAVSTGLVAAAAVAIPSANAAPAPATF FT SAAELSSAGNAVLQADVPGTAWAVDSKSGRVLLTVDSTVSQAEIAKIKEQAGDKADALT FT IKRTPGKFNKLIQGGDAIYASSWRCSLGFNVRTSSGAEYFLTAGHCTDGAGAWRASSGG FT TVIGQTAGSSFPGNDYGIVQYTGSVSRPGTANGVDITRAATPSVGTTVIRDGSTTGTHS FT GRVTALNATVNYGGGDVVGGLIQTTVCAEPGDSGGSLYGSNGTAYGLTSGGSGNCSSGG FT TTFFQPVTEALSAYGVSVY" FT misc_feature complement(46845..47384) FT /note="Pfam match to entry PF00089 trypsin, Trypsin, score FT 14.90, E-value 1.1e-05" FT repeat_region complement(46854..46929) FT /note="repeat 3; degenerate 76 bp direct repeat" FT misc_feature complement(46950..46985) FT /note="PS00135 Serine proteases, trypsin family, serine FT active site" FT repeat_region complement(46952..47088) FT /note="repeat 4; degenerate 137 bp direct repeat" FT repeat_region complement(47174..47243) FT /note="repeat 5; degenerate 70 bp direct repeat" FT repeat_region complement(47275..47321) FT /note="repeat 6; degenerate 47 bp direct repeat" FT misc_feature complement(47280..47297) FT /note="PS00134 Serine proteases, trypsin family, histidine FT active site" FT repeat_region complement(47326..47386) FT /note="repeat 7; degenerate 61 bp direct repeat" FT repeat_region complement(47457..47497) FT /note="repeat 8; degenerate 41 bp direct repeat" FT CDS complement(47937..48788) FT /transl_table=11 FT /gene="SCO1747" FT /gene_synonym="SCI11.36c" FT /product="conserved hypothetical protein" FT /note="SCI11.36c, hypothetical protein, len: 283 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Similar to TR:Q9PFB7 (EMBL:AE003917) hypothetical protein FT from Xylella fastidiosa (305 aa) fasta scores; opt: 394, FT Z-score: 443.5, E(): 4.5e-17, 35.094% identity (37.805% FT ungapped) in 265 aa overlap." FT /db_xref="InterPro:IPR012467" FT /db_xref="UniProtKB/TrEMBL:Q9S284" FT /protein_id="CAB50962.1" FT /translation="MTKGSPGDTPDKASDRAARGASDASDASDAWRRWHEQRVATVSAP FT YGPLALTGTHWLEDHPDGQLPDIPGRWTTDGDAVLLTAGRADGLTVDGRLLDGEARLTA FT DRGPVGAARVARGERRLVVLVREGLWGVRDFDPAAPARRAFRGIAATPYDPRWSVPGRF FT TPYDTGRRSVRVPNADGRERGLALGGELAFELDGRAHTLQVGVEDDGSLWAVFADATSG FT STSYRFRFLRPAAPDAEGRTTVDLNRALLPPCAFADHFVCPFPPPGNTLGARVEAGERE FT LR" FT CDS complement(48843..50039) FT /transl_table=11 FT /gene="SCO1748" FT /gene_synonym="2SCI34.01c" FT /gene_synonym="SCI11.37c" FT /product="putative expression regulator" FT /note="2SCI34.01c, probable expression regulator FT (fragment), len: >159 aa; highly similar to FT metallothionein-like proteins e.g. TR:Q9WX50 FT (EMBL:AB012145) Streptomyces lividans MrnA encoding FT metallothionein-like domain exhibiting repressor function FT against protease expression, 315 aa; fasta scores: opt: 507 FT z-score: 589.0 E(): 2.3e-25; 98.8% identity in 81 aa FT overlap" FT /note="SCI11.37c, probable expression regulator, partial FT CDS, len: >272 aa; highly similar to metallothionein-like FT proteins e.g. Streptomyces lividans CDS (EMBL:AB012145) FT exhibiting repressor function against protease expression FT (315 aa), fasta scores; opt: 1943 z-score: 1640.5 E(): 0, FT 97.8% identity in 272 aa overlap. The C-terminus contains a FT Pro-rich region (aa 170-200 approx.), followed by a FT Cys-rich region (aa 235-272 approx.). Contains PS00198 FT 4Fe-4S ferredoxins, iron-sulfur binding region signature" FT /db_xref="UniProtKB/TrEMBL:Q8CK20" FT /protein_id="CAD55176.1" FT /translation="MFGIVRPCRHRLGESLTSQWMAHLCGLCLALRKDHGQFARIVTNY FT DGLLISVLTEAQAGRGGAGAGRRTAGPCPLRGMRTASVAHGEGARLAAAVSLVLASAKV FT RDHVADGDGLLARRPVALAARRIAGGWDAAGARGGGAVGFDTAVLVDAVDRQGGIEALA FT GPGTPLLTVTEPTETATAAAFAHTAHLAGRPHNAVPLAEAGRLFGRLAHLLDAVEDREA FT DAASGAWNPLTATGTPLAEARRLADDAVHGVRLALREAEFTDGRLVHRLLVHELGSSVD FT RAFGTVSCAHGSHPYAPPGAPGTPGAPGGPGGPTPPEPPRRDRRGLLAGCAVWLGLACT FT CQMCCGTFNDPWSGQRREGLCSQCDCGNCCDCCDCCSNCCGDDGCGCGCDGCDCGCSC" FT misc_feature complement(48897..48932) FT /note="PS00198 4Fe-4S ferredoxins, iron-sulfur binding FT region signature" FT RBS complement(50044..50047) FT RBS 50318..50323 FT CDS 50329..50769 FT /transl_table=11 FT /gene="SCO1749" FT /gene_synonym="2SCI34.02" FT /product="conserved hypothetical protein" FT /note="2SCI34.02, conserved hypothetical protein, len: 146 FT aa; similar to TR:O06229 (EMBL:Z95388) Mycobacterium FT tuberculosis hypothetical 27.6 kDa protein MTCY270.21, 241 FT aa; fasta scores: opt: 311 z-score: 378.3 E(): 1.3e-13; FT 41.8% identity in 141 aa overlap" FT /db_xref="GOA:Q9EWX7" FT /db_xref="InterPro:IPR007561" FT /db_xref="UniProtKB/Swiss-Prot:Q9EWX7" FT /protein_id="CAC12922.1" FT /translation="MGSVRKASAWLGLVDDNNDDERYYDDDYSEGPESGDAWVTDPRVK FT VASDVAEEKGRRIATVTPDSFRDARAIGELFRDGVPVIVNLTAMEGTDAKRVVDFAAGL FT IFGLRGSIERVSTRVFLLSPADTQVISGESAAHRSDGFFNQS" FT CDS complement(50818..52011) FT /transl_table=11 FT /gene="SCO1750" FT /gene_synonym="2SCI34.03c" FT /product="putative acyl CoA dehydrogenase" FT /note="2SCI34.03c, probable acyl CoA dehydrogenase, len: FT 397 aa; similar to many dehydrogenases, e.g. SW:GCDH_HUMAN FT (EMBL:U69141) Homo sapiens (Human) glutaryl-CoA FT dehydrogenase, mitochondrial precursor (EC 1.3.99.7) GcdH, FT 438 aa; fasta scores: opt: 1208 z-score: 1358.9 E(): 0; FT 48.2% identity in 398 aa overlap. Contains 2x Pfam matches FT to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase" FT /db_xref="GOA:Q9EWX6" FT /db_xref="HSSP:1JQI" FT /db_xref="InterPro:IPR006092" FT /db_xref="UniProtKB/TrEMBL:Q9EWX6" FT /protein_id="CAC12923.1" FT /translation="MAASPKLPAFDPADPLGIDDLLEPEDLAVRDTVRSWAADRVLPHI FT ADWYESGELPGIRELARELGGIGALGMSLEGYGCAGASAVQYGLACLELEAADSGIRSL FT VSVQGSLAMYAIHRFGSEGQRQEWLPRMAGGEVIGCFGLTEPDHGSDPANMRTNAKRDT FT GGDWVLNGRKMWITNGSVAGVAVVWAQTEEGIRGFVVPTDSPGFSAPEIKHKWSLRASV FT TSELVLDDVRLPADAVLPEATGLRGPLSCLSHARYGIVWGSMGAARSSFEAAVEYAKSR FT EQFGRAIGGFQLTQAKLADMAVELHKGILLAHHLGRRMDAGRLRPEQVSFGKLNNVREA FT IDICRTARTILGANGISLEYPVMRHATNLESVLTYEGTVEMHQLVLGKALTGLDAFR" FT misc_feature complement(50848..50889) FT /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA FT dehydrogenase, score 0.70, E-value 23" FT misc_feature complement(51097..51948) FT /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA FT dehydrogenase, score 219.70, E-value 1.3e-63" FT CDS complement(52367..53971) FT /transl_table=11 FT /gene="SCO1751" FT /gene_synonym="2SCI34.04c" FT /product="putative transmembrane transport protein" FT /note="2SCI34.04c, probable transmembrane transport FT protein, len: 534 aa; similar to TR:O33968 (EMBL:U80063) FT Streptomyces cinnamoneus putative transmembrane, FT proton-dependent transport protein, 519 aa; fasta scores: FT opt: 1250 z-score: 1258.8 E(): 0; 43.9% identity in 513 aa FT overlap and to SW:SMVA_SALTY (EMBL:D26057) Salmonella FT typhimurium methyl viologen resistance protein SmvA, 496 FT aa; fasta scores: opt: 1018 z-score: 1026.6 E(): 0; 37.4% FT identity in 497 aa overlap. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q9EWX5" FT /db_xref="InterPro:IPR018245" FT /db_xref="UniProtKB/TrEMBL:Q9EWX5" FT /protein_id="CAC12924.1" FT /translation="MSGTTTAAAAPRRRAAGAGANRWVVLVVLCVSLLLVAVDATVLHV FT AVPAVTEDLRPGAIELLWIVDVYPLVCASLLILFGTLGDRVGRRRVLLLGYALFGVASA FT LAALADTAQVLIAARALLGVGGAMIMPATLSILRQVFPDRRERALAIGIWSAVAAVGAA FT VGPLLGGFLLEHFWWGSVFLVNIPLMLVSLPVGRLLLPESKGDGRGPWDVVGALMAAGG FT LFGAVLGVKRLGGGEPAASLLTVLPLVLGAALLAGFVRRQRRRTYPLVDLAMFRRPAFS FT TSVGCIVLAMLALVGLELIAAQYLQLVLGLSPLETGLRLLPLTFAAMAAGLAGARLLRR FT FGPRRMVCAGFCLTAFAVVLLTAMGRADNCALLLTGFVLLGFGLETTLFGAYESMLSEA FT PQEQSGGAAAIGETSYQLGAGIGIALLGSVMNAAYAPGLTGGVPGVPAPASAAAGHSLG FT EAYEVAAQLGGPAGVALRRAAGDAFVHGLHVTLVVSAGLLLLGAVMALRLPRAMQCEEV FT SVPAPRGAVDSPSRVSV" FT RBS complement(53978..53983) FT CDS 54233..55423 FT /transl_table=11 FT /gene="SCO1752" FT /gene_synonym="2SCI34.05" FT /product="putative integral membrane protein" FT /note="2SCI34.05, possible integral membrane protein, len: FT 396 aa; similar to TR:Q9L0K6 (EMBL:AL161691) Streptomyces FT coelicolor putative integral membrane protein SCD40A.03c, FT 434 aa; fasta scores: opt: 678 Z-score: 715.1 E(): 3.4e-32; FT 37.530% identity in 413 aa overlap. Contains possible FT hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9EWX4" FT /protein_id="CAC12925.1" FT /translation="MTDLETRGAARRGAPGPSGALRRAAPALLGYAAVRALGLLALALW FT SAARDKSAYTLLTARWDSLWYTRVAELGYGYEVRLPSGDVHSNLAFFPLLPWLERLGAA FT VTPLSYADTGFVVSLLASLAAAWGIFAVAEHVHDRRVGVCAVLLWAVLPVGVVQSMAYS FT ESLFTALAAWSLYAVLTGRWVTAGALAALAGLTRPVGLAVTAAVWAAAVIAFARSRSEG FT GAGDAGGTPGARRVLGMLLAPLGAAGYVLWVGHRTGKGPLGYLDVQAGWRNGFDGGAAF FT ARFVAAQFTSFPGALAGVGLIVGVALLVWLYVVCVRQRQPLPLLVYAGLVTVLALCASS FT YFGSKPRLLLPAFPLLFPPAVGLARLRTARSAPVVCGVAVAAAVYGAFWLNGSGPP" FT CDS 55675..56697 FT /transl_table=11 FT /gene="SCO1753" FT /gene_synonym="2SCI34.06" FT /product="putative integral membrane protein" FT /note="2SCI34.06, possible integral membrane protein, len: FT 340 aa. Contains Pfam match to entry PF01569 PAP2, PAP2 FT superfamily and possible hydrophobic membrane spanning FT regions. Also presents high content of alanine, arginine, FT leucine and proline amino acid residues" FT /db_xref="GOA:Q9EWX3" FT /db_xref="InterPro:IPR016118" FT /db_xref="UniProtKB/TrEMBL:Q9EWX3" FT /protein_id="CAC12926.1" FT /translation="MRTERKPTRLDRVFARLDREPERPALLDVPEMSRHRIALFAGTLA FT FYIAIVWAVVITSWLVRLDWQVMFFRPYQQWPEIHAFVDYYVVLGQRGPTAVMVAAWLG FT WRSWRQHTLRPLLALGVSLLLLNVTVGAAKYGMGRLGPHYATTIGANEMWLGGDIFPSG FT HTANAVVTWGILAYLASTHRTRRWLSAISAVTSLGVGMSTVYLGTHWLSDVLLGWVAGL FT LILLALPWFEPLITRAEAWILGLRDRWYTRRDRRSTTRPPLGPPVPVSPPGSGSRPQAP FT AREPVAAPRTARAPAHLAPGPHTARSDRTPVTPAGSRRPPHSDRHARNTAPTARPLSGG FT " FT misc_feature 55933..56382 FT /note="Pfam match to entry PF01569 PAP2, PAP2 superfamily, FT score 27.20, E-value 0.00039" FT CDS complement(56810..57025) FT /transl_table=11 FT /gene="SCO1754" FT /gene_synonym="2SCI34.07c" FT /product="hypothetical protein 2SCI43.07c" FT /note="2SCI34.07c, unknown, len: 71 aa" FT /db_xref="UniProtKB/TrEMBL:Q9EWX2" FT /protein_id="CAC12927.1" FT /translation="MAPIPTPPAEPQDSPDTYVGLDSDAAERLARERGWSTVRSLAPGT FT VITMEYRVGRLNFEVKDGRVSRAWKG" FT CDS complement(57369..58217) FT /transl_table=11 FT /gene="SCO1755" FT /gene_synonym="2SCI34.08c" FT /product="conserved hypothetical protein 2SCI34.08c" FT /note="2SCI34.08c, unknown, len: 282 aa; similar to FT TR:CAC47960 (EMBL:AJ320278) Streptomyces avermitilis FT hypothetical protein, 278 aa; fasta scores: opt: 962 FT Z-score: 1035.8 E():4.6e-50; 63.441% identity in 279 aa FT overlap" FT /db_xref="UniProtKB/TrEMBL:Q9EWX1" FT /protein_id="CAC12928.1" FT /translation="MPPPPSPAAPLRADCIGDSAGGLTFDVAARGNAGAALLVLRRRAA FT DAPDGEGETVSLPLAPAAEGRLRAALPSSVSLPEGRWDAYALLSGGEPRRLVPGVTDLR FT SLAERTPSGLLGHVAVRIPYATRQGNLTVRSWLRAPHAEAVELRLASGGLTVRGRVYGT FT QFVPGADAELRARPGDGAGGEDGGGVRRVHVTAERTEFTFTVPYEGLVPGVWDLWLRPA FT GDAGPVVRLARLLDDVADKNPVFTFPRARVRTPQGPVEAGPYYTRDNDLSLTVSPLDAD FT A" FT RBS complement(58229..58233) FT RBS 58617..58620 FT CDS 58627..59424 FT /transl_table=11 FT /gene="SCO1756" FT /gene_synonym="2SCI34.09" FT /product="hypothetical protein 2SCI34.09" FT /note="2SCI34.09, unknown, len: 265 aa" FT /db_xref="UniProtKB/TrEMBL:Q9EWX0" FT /protein_id="CAC12929.1" FT /translation="MPRMLDVSDDVRAEIGDEEADRLLAGESAPGSYDCTSCRTPGDCE FT QERTSTVLFIGDETAVLAFAHAGCLPSQVVKVTEEQLQGAVRSISADQARSESAPAAPE FT KAAPEQAVLGVTSGLILIAGELHPALVVEPTAPIARPGTSGAGDDFLPLLIEQGFMPVT FT ELASTPAVLHGWSVLLAMGQLHAVLQPGTNGGRPVAWWQAHQPLQVTEGWRTAANKHQQ FT VLMFAAPVGSIGRQPREDLLRDALDKAAANGQLVAAALPLAGT" FT CDS 59498..59791 FT /transl_table=11 FT /gene="SCO1757" FT /gene_synonym="2SCI34.10" FT /product="hypothetical protein 2SCI34.10" FT /note="2SCI34.10, unknown, len: 97 aa" FT /db_xref="UniProtKB/TrEMBL:Q9EWW9" FT /protein_id="CAC12930.1" FT /translation="MYAYDAFHRHGGPSATPIYDALYAEYVRSFRSLPGDRSGEEELGF FT TAFRSIPRGRGGYSAYSAGAQSARVGQQSVWQRVGGTHHVPAALPPAPRSGT" FT stem_loop complement(59802..59853) FT /note="possible stem loop. Score 78: 25/25 (100%) matches, FT 0 gaps" FT CDS complement(59870..61348) FT /transl_table=11 FT /gene="SCO1758" FT /gene_synonym="2SCI34.11c" FT /product="putative GTP binding protein" FT /note="2SCI34.11c, probable GTP binding protein, len: 492 FT aa; similar to SW:ENGA_BACSU (EMBL:L47648) Bacillus FT subtilis probable GTP binding protein EngA, 436 aa; fasta FT scores: opt: 1143 z-score: 1175.4 E(): 0; 42.0% identity in FT 436 aa overlap. Contains Pfam match to entry PF01926 FT MMR_HSR1, GTPase of unknown function and 2x matches to FT Prosite entry PS00017 ATP/GTP-binding site motif A FT (P-loop)" FT /db_xref="GOA:Q9EWW8" FT /db_xref="HSSP:1MKY" FT /db_xref="InterPro:IPR005225" FT /db_xref="UniProtKB/Swiss-Prot:Q9EWW8" FT /protein_id="CAC12931.1" FT /translation="MNDHIHPEGSGAEHDHGALGDAEYAQFMELAAEEGFDIEDVEGAI FT EEAGHGPLPVLAVVGRPNVGKSTLVNRIIGRREAVVEDKPGVTRDRVTYEAEWAGRRFK FT VVDTGGWEQDVLGIDASVAAQAEYAIEAADAVVFVVDAKVGATDTDEAVVRLLRKAGKP FT VVLCANKVDGPSGEADASYLWSLGLGEPQPVSALHGRGTGDMLDRVLEALPEAPAQTFG FT TAVGGPRRIALIGRPNVGKSSLLNKVAGEDRVVVNELAGTTRDPVDELIELGGVTWKFV FT DTAGIRKRVHLQQGADYYASLRTAAAVEKAEVAVILVDASESISVQDQRIVTMAVEAGR FT AIVVAYNKWDTLDEERRYYLEREIETELGQVAWAPRVNVSAQTGRHMEKLVPAIETALA FT GWETRVPTGRLNAFLGELAAAHPHPVRGGKQPRILFGTQAGTKPPRFVLFASGFIEAGY FT RRFIERRLREEFGFEGTPIHISVRVREKRGAKKK" FT misc_feature complement(60209..60985) FT /note="Pfam match to entry PF01926 MMR_HSR1, GTPase of FT unknown function, score 107.00, E-value 3.8e-28" FT misc_feature complement(60623..60646) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(61148..61171) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(61358..61362) FT CDS complement(61423..62085) FT /transl_table=11 FT /gene="SCO1759" FT /gene_synonym="2SCI34.12c" FT /product="putative transferase" FT /note="2SCI34.12c, possible transferase, len: 220 aa; FT similar to TR:O67841 (EMBL:AE000770) Aquifex aeolicus FT 2-acylglycerophosphoethanolamine acyltransferase Aas, 211 FT aa; fasta scores: opt: 325 z-score: 388.0 E(): 3.6e-14; FT 33.3% identity in 189 aa overlap. Contains Pfam match to FT entry PF01553 Acyltransferase, Acyltransferase" FT /db_xref="GOA:Q9EWW7" FT /db_xref="InterPro:IPR002123" FT /db_xref="UniProtKB/TrEMBL:Q9EWW7" FT /protein_id="CAC12932.1" FT /translation="MTASSAAPAPSEKGAEVGRRIGVGLMYGLWKPRVLGAWRVPATGP FT VIYAVNHAHNIDGPMVMGVAPRPTHFLIKKEAFVGPLGRFLTGIGQLKVDRHSADRAAI FT GQALGVLADGGVLGIFPEGTRGEGDFASLRAGLAYFAVRSGAPIVPVAVLGSTDRPGRL FT IKALPPLRSRVDVVFGDPFDAGDGSGRRTRKALDEATERIQKQLTAHLENARRLTGR" FT misc_feature complement(61444..61977) FT /note="Pfam match to entry PF01553 Acyltransferase, FT Acyltransferase, score 83.10, E-value 5.9e-21" FT CDS complement(62082..62777) FT /transl_table=11 FT /gene="SCO1760" FT /gene_synonym="2SCI34.13c" FT /product="putative cytidylate kinase" FT /note="2SCI34.13c, probable cytidylate kinase, len: 231 aa; FT similar to SW:KCY_ECOLI (EMBL:X00785) Escherichia coli FT cytidylate kinase (EC 2.7.4.14) Cmk or MssA, 227 aa; fasta FT scores: opt: 469 z-score: 501.3 E(): 1.8e-20; 40.3% FT identity in 226 aa overlap. Contains Pfam match to entry FT PF02224 Cytidylate_kin, Cytidylate kinase and match to FT Prosite entry PS00017 ATP/GTP-binding site motif A FT (P-loop)" FT /db_xref="GOA:Q9EWW6" FT /db_xref="HSSP:1KDO" FT /db_xref="InterPro:IPR011994" FT /db_xref="UniProtKB/Swiss-Prot:Q9EWW6" FT /protein_id="CAC12933.1" FT /translation="MENGAAPTAPAVIVAIDGPSGTGKSSTSKAVAAQLGLSYLDTGAQ FT YRAITWWMVTNGIDTDDPHAVAAAAGKPEIVSGTDPAGPTITVDGVDVAGPIRTQEVTS FT KVSAVSAVPEVRARITELQRTIAAAAPLGIVVEGRDIGTTVLPDADLKIFLTASAEARA FT ARRSGELKGADVHATREALIKRDAADSSRKTSPLAKAGDAVEVDTTALSLPQVIECVVT FT LVEEKRAGK" FT misc_feature complement(62112..62579) FT /note="Pfam match to entry PF02224 Cytidylate_kin, FT Cytidylate kinase, score 180.00, E-value 3.8e-50" FT misc_feature complement(62703..62726) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(62785..62789) FT CDS complement(63065..64150) FT /transl_table=11 FT /gene="SCO1761" FT /gene_synonym="SCI51.01c" FT /gene_synonym="2SCI34.14c" FT /product="putative cyclohexadienyl dehydrogenase" FT /note="SCI51.01c, possible cyclohexadienyl dehydrogenase, FT partial CDS, len: >212 aa; similar to several FT cyclohexadienyl dehydrogenases e.g. SW:TYRC_ZYMMO FT (EMBL:M75891), TyrC, Zymomonas mobilis cyclohexadienyl FT dehydrogenase (293 aa), fasta scores; opt: 299 z-score: FT 344.0 E(): 7.8e-12, 31.4% identity in 220 aa overlap. Also FT similar to other hypothetical oxidoreductases e.g. FT CZA382.29 (EMBL:AL078635) Streptomyces coelicolor putative FT oxidoreductase (367 aa) (55.8% identity in 208 aa overlap)" FT /note="2SCI34.14c, possible oxidoreductase (fragment) FT (putative secreted protein), len: >182 aa; similar to FT TR:Q9Z4W3 (EMBL:AL035654) Streptomyces coelicolor putative FT oxidoreductase SCE8.14c, 284 aa; fasta scores: opt: 301 FT z-score: 343.0 E(): 1.2e-11; 50.5% identity in 107 aa FT overlap. Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="GOA:Q8CK19" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q8CK19" FT /protein_id="CAD55177.1" FT /translation="MRTALVIGTGLIGTSAALALTERGVTVHLADHDPEQARTAAALGA FT GTDEAPDGPVDLAVVAAPPALVADVLADAMARGLARGYIDVASVKGGPRRELEARGLDL FT SAYIGTHPMSGREKSGPLAATADLFEGRPWVLTPTRDTDTEVLNLALELVSHCRAVPVV FT MDADAHDRAVALVSHMPHLVSSMVAARLEHAEEAAVRLCGQGIRDVTRIAASDPRMWID FT ILSANPGPVADLLTDVAADLEETVRALRALQSTDEDKRREGGTGIAEVLRRGNAGQVRV FT PGKHGSAPRSYETVAVLIDDQPGQLARIFADAGRAGVNVEDVRIEHATGQQAGLVQLMV FT EPKAAAVLTAALKERGWAIRQ" FT CDS complement(64147..64509) FT /transl_table=11 FT /gene="SCO1762" FT /gene_synonym="SCI51.02c" FT /product="putative chorismate mutase" FT /note="SCI51.02c, possible chorismate mutase, len: 120 aa; FT similar to e.g. SW:CHMU_BACSU (EMBL:M32278), AroH, Bacillus FT subtilis chorismate mutase (127 aa), fasta scores; opt: 307 FT z-score: 407.7 E(): 2.2e-15, 38.1% identity in 118 aa FT overlap" FT /db_xref="HSSP:1UFY" FT /db_xref="InterPro:IPR013813" FT /db_xref="UniProtKB/TrEMBL:Q9S238" FT /protein_id="CAB52826.1" FT /translation="MAVRAVRGAVQLERDEAGHMGEQVAALLTALMERNGLTADDLISL FT WFTATPDLHSDFPAAAARGLGITDVPLICAQELDVEGAMPRVVRVLAHIESERPRTGIA FT HVYLGAAAALRKDIAQ" FT CDS 64671..65066 FT /transl_table=11 FT /gene="SCO1763" FT /gene_synonym="SCI51.03" FT /product="putative iron-sulphur protein (putative secreted FT protein)" FT /note="SCI51.03, possible iron-sulphur protein (putative FT secreted protein), len: 131 aa; similar to part of many FT cytochrome B6-F complex iron-sulfur subunits from bacteria FT and chloroplasts e.g. SW:UCRI_CHLLT (EMBL:X73628), PetC, FT Chlorobium limicola F. sp. thiosulfatophilum iron-sulfur FT subunit (180 aa), fasta scores; opt: 198 z-score: 217.9 FT E(): 8.2e-05, 34.4% identity in 90 aa overlap. Similar to FT TR:Q9Z510 (EMBL:AL035591) Streptomyces coelicolor putative FT iron sulphur binding protein (141 aa) (36.6% identity in FT 131 aa overlap). Contains Pfam match to entry PF00355 FT Rieske, Rieske iron-sulfur protein. Contains possible FT N-terminal region signal peptide sequence" FT /db_xref="GOA:Q9S237" FT /db_xref="HSSP:1JM1" FT /db_xref="InterPro:IPR005805" FT /db_xref="UniProtKB/TrEMBL:Q9S237" FT /protein_id="CAB52827.1" FT /translation="MTQTPARRTVLLCTGAGAAALCVGCGGGGDSSGASPGQELVRTGD FT VPVAGGKILTDEKIVVTQPRQGEFKAFSAVCTHQGCIVSDVRDGTIDCACHGSRFAVAD FT GSVVRGPATEPLPGKRITVEGNSVRLA" FT misc_feature 64890..65018 FT /note="Pfam match to entry PF00355 Rieske, Rieske FT iron-sulfur protein, score 25.60, E-value 7.4e-07" FT CDS 65089..65850 FT /transl_table=11 FT /gene="SCO1764" FT /gene_synonym="SCI51.04" FT /product="hypothetical protein" FT /note="SCI51.04, hypothetical protein, len: 253 aa; unknown FT function, shows weak similarity to TR:P94389 (EMBL:D50453), FT YcgL, Bacillus subtilis hypothetical protein (260 aa), FT fasta scores; opt: 177 z-score: 222.1 E(): 5.1e-05, 28.1% FT identity in 196 aa overlap. There is some overlap with the FT C-terminus of SCI51.5c and weak similarity with SCI51.5c FT (250 aa) (29.6% identity in 233 aa overlap)" FT /db_xref="InterPro:IPR018775" FT /db_xref="UniProtKB/TrEMBL:Q9S236" FT /protein_id="CAB52828.1" FT /translation="MRPEAPGSHELLVRDHTVYACVMGSRAFGLATEDSDTDRRGVFLA FT PTALFWRFDKPPTHVEGPGEEQFSWELERFCELALRANPNILECLHSPLVESVDDTGRE FT LLALREAFLSRRVHETFTRYAHGQRRKLDADVRTHGAPRWKHAMHVLRLLISARDLLRT FT GVLTIDVGAARESLLAVRRGEVPWPEVEARMTRLAREGEEAAARSPLPGEPDRRRVEDF FT LVRTRRASALQPGPYDEVVQGVVRGRGVGEH" FT CDS complement(65776..66528) FT /transl_table=11 FT /gene="SCO1765" FT /gene_synonym="SCI51.05c" FT /product="hypothetical protein" FT /note="SCI51.05c, hypothetical protein, len: 250 aa; FT unknown function, similar to SW:Y002_METJA (EMBL:U67459) FT Methanococcus jannaschii hypothetical protein (243 aa), FT fasta scores; opt: 290 z-score: 356.7 E(): 1.6e-12, 28.3% FT identity in 223 aa overlap. There is some overlap with the FT C-terminus of SCI51.04 and weak similarity with SCI51.04 FT (253 aa) (29.6% identity in 233 aa overlap)" FT /db_xref="InterPro:IPR018775" FT /db_xref="UniProtKB/TrEMBL:Q9S235" FT /protein_id="CAB52829.1" FT /translation="MIDALDIDLAPVVAEQPFPVLFATVSGAHLYGFPSRDSDVDLRGA FT HLLPAADLVGLREPEETRSRMWDRDGVEMDLVTHDLRKFVRLMLRRNGYVLEQLLSPLV FT VHTTEAHRELAGHAPGVLTAHHAHHYRGFAQTQWRLFERTGELKPLLYTFRVLLTGVHL FT MRTGEVQPHLPTLVEEVDAAPVYLPELVAAKAEREHGDAGVDHARVRADVERLHTVLDE FT AQAASVLPDAPTAYDALHDFVVRTRLER" FT CDS complement(66533..67552) FT /transl_table=11 FT /gene="SCO1766" FT /gene_synonym="SCI51.06c" FT /product="putative glycohydrolase" FT /note="SCI51.06c, possible glycohydrolase, len: 339 aa; FT shows weak similarity to ADP-ribosyl glycohydrolases from FT nitrogen-fixing bacteria e.g. SW:DRAG_RHORU (EMBL:X16187), FT DraG, Rhodospirillum rubrum ADP-ribosylglycohydrolase (294 FT aa), fasta scores; opt: 211 z-score: 253.7 E(): 8.9e-07, FT 25.6% identity in 332 aa overlap" FT /db_xref="GOA:Q9S234" FT /db_xref="InterPro:IPR005502" FT /db_xref="UniProtKB/TrEMBL:Q9S234" FT /protein_id="CAB52830.1" FT /translation="MTTTGTKRPATGALTGLALGDALGFPTEFNDVPAILAKCGPWREM FT ALPRPAIVTDDTQMTLALGKGLRTAMDRGLLGPKRMERPVREEFVDWYQSPENNRAPGN FT TCLKACNLLKAPDRPWQDASQIHSKGCGANMRVAPVGLVPGLSDEQRAGAAQLQSALTH FT GHPTALAASDLTAHAVRLLAEGAEPTGLVGLLRSYAYDNRTRYHERWLGDLWSRAQDPT FT PEHFIARGWDECLAILDRLQEAVRTVSPETDPCLAVGEGWIAEEAMAAGLLCFLLFVDE FT PLTALRRGACTSGDSDSIACLAGAFAGAHLGADAWPADWADRIEYRGDLLALGALWDA" FT CDS complement(67549..68268) FT /transl_table=11 FT /gene="SCO1767" FT /gene_synonym="SCI51.07c" FT /product="putative DNA hydrolase" FT /note="SCI51.07c, possible DNA hydrolase, len: 239 aa; FT shows weak similarity to nucleotide pyrophosphatases e.g. FT TR:Q58549 (EMBL:U67557) Methanococcus jannaschii ADP-ribose FT pyrophosphatase (169 aa), fasta scores; opt: 256 z-score: FT 312.0 E(): 5e-10, 43.8% identity in 112 aa overlap and FT SW:MUTX_STRMU (EMBL:D78182), MutX, Streptococcus mutans FT mutator MutT protein (dGTP pyrophosphohydrolase) (159 aa) FT (30.5% identity in 118 aa overlap). Also similar many FT hypothetical proteins e.g. TR:O69994 (EMBL:AL022374) FT S.coelicolor possible DNA hydrolase (294 aa) (56.2% FT identity in 249 aa overlap) and TR:O06597 (EMBL:Z95586) FT Mycobacterium tuberculosis hypothetical protein (236 aa) FT (34.8% identity in 221 aa overlap). Contains Pfam match to FT entry PF00293 mutT, Bacterial mutT protein and PS00893 FT mutT domain signature" FT /db_xref="GOA:Q9S233" FT /db_xref="InterPro:IPR020084" FT /db_xref="UniProtKB/TrEMBL:Q9S233" FT /protein_id="CAB52831.1" FT /translation="MHGYDKHAFEPFAVTVDLAVLTLRAGALHALLVERGQEPYAGRWA FT LPGGFLLPAESAEEAARRELAEETGLADVTGLHLEQLRTYSEPGRDPRMRVVSVAFAAL FT LPDPPEPHGGGDAAEARWVPYDKAQGLAFDHDRILADARDRVGAKLEYTCLATAFCPAE FT FTLGELQQVYETVWGTALDRPNFRRKVLATPGFVEPVPGAARLTGGRGKPAAVYRAGPA FT TTLHPPLLRTPREGRPA" FT misc_feature complement(68056..68181) FT /note="Pfam match to entry PF00293 mutT, Bacterial mutT FT protein, score 36.50, E-value 5.7e-09" FT misc_feature complement(68065..68124) FT /note="PS00893 mutT domain signature" FT CDS complement(68362..69477) FT /transl_table=11 FT /gene="SCO1768" FT /gene_synonym="SCI51.08c" FT /product="putative pseudouridine synthase" FT /note="SCI51.08c, possible pseudouridine synthase, len: 371 FT aa; part of this CDS shows similarity to SW:RSUA_ECOLI FT (EMBL:U00008), rsuA, Escherichia coli ribosomal small FT subunit pseudouridine synthase A (231 aa), fasta scores; FT opt: 389 z-score: 356.8 E(): 1.6e-12, 35.2% identity in 233 FT aa overlap and to many putative pseudouridine synthases. FT Similarity to SW:YRSU_MYCLE (EMBL:Z95117) Mycobacterium FT leprae hypothetical protein (256 aa) (54.6% identity in 240 FT aa overlap) and its Mycobacterium tuberculosis counterpart FT is high. GC frameplot and an absence of possible start FT codons suggests that an N-terminal extension of approx. 130 FT aa is present in this sequence, but not in similar FT sequences. The N-terminus is Ser- and Gly-rich. Contains FT Pfam matches to entry PF01479 S4, S4 domain and to entry FT PF00849 YABO, Hypothetical yabO/yceC/sfhB family. Contains FT PS01149 RsuA family of pseudouridine synthase signature" FT /db_xref="GOA:Q9S232" FT /db_xref="HSSP:1VIO" FT /db_xref="InterPro:IPR018496" FT /db_xref="UniProtKB/TrEMBL:Q9S232" FT /protein_id="CAB52832.1" FT /translation="MRSSSGRNSSGNNGGSRGGNSGGRGGSSGGRGNHRGAGNNRDDKQ FT GGRPKKPRPEERRYDVGPGATQDGPKSGRGPSARGGAKGGPKRPQQRGRSAPATSREYE FT TRAEERNRERYAGKKDVKLPKTFPGAEQEGERLQKVLARAGYGSRRACEELIEQARVEI FT NGEIVLEQGRRVDPEKDEVKVDGLTVATQSYQFFSLNKPAGVVSTMEDPEGRQCLGDYV FT TNRETRLFHVGRLDTETEGVILLTNHGELAHRLTHPRYGVKKTYLAHIVGPIPRDLGKR FT LKDGIQLEDGYARADHFRVVEQTGKNYLVEVTLHEGRKHIVRRMLAEAGFPVDNLVRTA FT FGPITLGDQKSGWLRRLSNTEVGMLMQEVDL" FT misc_feature complement(68485..68895) FT /note="Pfam match to entry PF00849 YABO, Hypothetical FT yabO/yceC/sfhB family, score -7.50, E-value 1.7e-05" FT misc_feature complement(68737..68781) FT /note="PS01149 RsuA family of pseudouridine synthase FT signature" FT misc_feature complement(68893..69075) FT /note="Pfam match to entry PF01479 S4, S4 domain, score FT 42.90, E-value 7.1e-09" FT CDS complement(69477..70148) FT /transl_table=11 FT /gene="SCO1769" FT /gene_synonym="SCI51.09c" FT /product="conserved hypothetical protein" FT /note="SCI51.09c, conserved hypothetical protein, len: 223 FT aa; unknown function, similar to hypothetical proteins from FT Mycobacterium leprae and Mycobacterium tuberculosis e.g. FT TR:O05669 (EMBL:Z95117) Mycobacterium leprae hypothetical FT protein (231 aa), fasta scores; opt: 633 z-score: 766.9 FT E(): 0, 54.5% identity in 187 aa overlap" FT /db_xref="GOA:Q9S231" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9S231" FT /protein_id="CAB52833.1" FT /translation="MSERITEAEEATEAEGGPDGVAALDLKPALEAVLMVVDEPATEER FT LAKILQRPRRRIADALRELADEYAVQGRGFELRLIAGGWRFYSRPEYAAAVEGFVLDGQ FT HARLTQAALETLAVVAYRQPVSRGRVSAVRGVNCDGVMRTLLQRGLVEEAGTEPETGAI FT LYVTTNYFLERMGLRGLDELPELAPFLPEAEAIEADTLEGVPSFDPDAPDAGDADDKTE FT F" FT CDS complement(70145..70939) FT /transl_table=11 FT /gene="SCO1770" FT /gene_synonym="SCI51.10c" FT /product="conserved hypothetical protein" FT /note="SCI51.10c, conserved hypothetical protein, len: 264 FT aa; unknown function, similar to hypothetical proteins from FT Mycobacterium leprae, Mycobacterium tuberculosis and FT Bacillus subtilis e.g. TR:O33208 (EMBL:Z98268) FT Mycobacterium tuberculosis hypothetical protein (278 aa), FT fasta scores; opt: 875 z-score: 760.8 E(): 0, 56.2% FT identity in 267 aa overlap" FT /db_xref="GOA:Q9S230" FT /db_xref="InterPro:IPR003768" FT /db_xref="UniProtKB/TrEMBL:Q9S230" FT /protein_id="CAB52834.1" FT /translation="MRLANFEGPFDLLLQLISKHKLDVTEVALSKVTDEFMAHIRAMGP FT DWDLDQTTEFLVVAATLLDLKAARLLPAAEVEDEADLALLEARDLLFARLLQYRAYKQI FT AEIFNDRLEAEARRHPRTVGLEPHHAELLPEVVISIGPEGFAKLAVKAMQPKPRPQVYV FT EHIHAPLVSVQEQAGIVVARLKELGEASFRVLVQDTEDTLTVVARFLALLELYREKAVE FT LDQETALGDLLVRWTGGDGEAQPSVTDEFDRPPEVPKEERKA" FT CDS complement(71471..72028) FT /transl_table=11 FT /gene="SCO1771" FT /gene_synonym="SCI51.11c" FT /product="hypothetical protein" FT /note="SCI51.11c, hypothetical protein, len: 185 aa; FT unknown function, improbable CDS suggested by positional FT base preference and amino acid composition" FT /db_xref="UniProtKB/TrEMBL:Q9S229" FT /protein_id="CAB52835.1" FT /translation="MSLPGADELFRTTGGTALQASTPRRPAGGEARVPAPAGESDQAAA FT EDAPQSVPAQGGDGEGAEHAAADAEPGSAGESRTRGTERSARGSGPGSGAQEGSAADRP FT RKRGRSPSRRPSGRERHDEKITVYVSAEELMDLEHARLVLRGEHGLAVDRGRIVREAVA FT VVLADLETRGDASILVRRLRGR" FT CDS complement(72025..73047) FT /transl_table=11 FT /gene="SCO1772" FT /gene_synonym="SCI51.12c" FT /product="putative partitioning or sporulation protein" FT /note="SCI51.12c, possible partitioning or sporulation FT protein, len: 340 aa; the C-terminal region is similar to FT SW:SOJ_BACSU (EMBL:D26185), Soj, Bacillus subtilis FT sporulation protein (253 aa), fasta scores; opt: 790 FT z-score: 857.6 E(): 0, 48.8% identity in 250 aa overlap and FT TR:O05189 (EMBL:U87804), ParA, Caulobacter crescentus FT chromosome partitioning protein (266 aa) (46.3% identity in FT 255 aa overlap). It is closer in predicted length to FT similar proteins from Mycobacterium tuberculosis and FT Mycobacterium leprae e.g. TR:O33207 (EMBL:Z98268) FT Mycobacterium tuberculosis hypothetical protein (318 aa) FT (65.8% identity in 301 aa overlap). Similar to SCH24.08 FT (EMBL:AL049826) S.coelicolor possible partitioning or FT sporulation protein (275 aa) (45.8% identity in 249 aa FT overlap) to many other members of the parA family. The FT start codon position is suggested by GC frameplot and codon FT usage plots. Alternative start codons are present at codons FT 3, 8 and 11. Contains Pfam match to entry PF00991 ParA, FT ParA family ATPase" FT /db_xref="GOA:Q9S228" FT /db_xref="HSSP:1IHU" FT /db_xref="InterPro:IPR002586" FT /db_xref="UniProtKB/TrEMBL:Q9S228" FT /protein_id="CAB52836.1" FT /translation="MSMDGQHVNAMAGDGSGAPRNHFADYDELPEGHFYDPDAEYEPDP FT EYAATLAPDAARQRRERIGPTGRPLPYFPIPGPLTDHGPAKIIAMCNQKGGVGKTTSTI FT NLGAALAEYGRRVLLVDFDPQGALSVGLGVNPMELDLTVYNLLMERGMAADEVLLKTAV FT PNMDLLPSNIDLSAAEVQLVSEVARESTLQRALKPLMDDYDYIVIDCQPSLGLLTVNAL FT TAAHKVIVPLECEFFALRGVALLTETIEKVQERLNPDLELDGILATMYDSRTVHSREVL FT ARVVEAFDDHVYHTVIGRTVRFPETTVAGEPITTYASNSVGAAAYRQLAREVLARCHAE FT " FT misc_feature complement(72211..72546) FT /note="Pfam match to entry PF00991 ParA, ParA family FT ATPase, score 150.20, E-value 3.6e-41" FT stem_loop complement(73451..73497) FT /note="stem, 21/21 (100%) matches, 0 gaps; loop, 5 bp" FT CDS complement(73543..74658) FT /transl_table=11 FT /gene="SCO1773" FT /gene_synonym="SCI51.13c" FT /product="putative L-alanine dehydrogenase" FT /note="SCI51.13c, probable L-alanine dehydrogenase, len: FT 371 aa; similar to many alanine dehydrogenases e.g. FT SW:DHA_MYCTU (EMBL:X63069), ald, Mycobacterium FT tuberculosis L-alanine dehydrogenase (371 aa), fasta FT scores; opt: 1569 z-score: 1722.1 E(): 0, 65.8% identity in FT 371 aa overlap. Contains Pfam match to entry PF01262 FT AlaDh_PNT, Alanine dehydrogenase/pyridine nucleotide FT transhydrogenase and PS00836 Alanine dehydrogenase & FT pyridine nucleotide transhydrogenase signature 1" FT /db_xref="GOA:Q9S227" FT /db_xref="HSSP:1SAY" FT /db_xref="InterPro:IPR008142" FT /db_xref="UniProtKB/TrEMBL:Q9S227" FT /protein_id="CAB52837.1" FT /translation="MKVGIPREVKNNEFRVAITPAGVHELVRHGHQVVVERNAGVGSSI FT PDEEYVTAGARILDTADEVWATADLLLKVKEPIAEEYHRLRKDQTLFTYLHLAASKECT FT DALIESRTTAIAYETVELPSRALPLLAPMSEVAGRLAPQVGAYHLMAANGGRGVLPGGV FT PGVLAGRAVVIGGGVSGWNAAQIAIGLGFHVTLLDKDITKLREADKIFGTKIQTVVSNA FT FELEKACLEADLVIGAVLIPGAKAPKLVTNELVSRMKPGSVLVDIAIDQGGCFEDSHPT FT THAEPTFPVHNSVFYCVANMPGAVPNTSTYALTNATLPYIVELADRGWAEALRRDPALA FT KGLNTHDGKVVYREVAEAHGLEHVELASLLA" FT misc_feature complement(73546..74658) FT /note="Pfam match to entry PF01262 AlaDh_PNT, Alanine FT dehydrogenase/pyridine nucleotide transhydrogenase, score FT 656.50, E-value 1.4e-193" FT misc_feature complement(74569..74649) FT /note="PS00836 Alanine dehydrogenase & pyridine nucleotide FT transhydrogenase signature 1" FT CDS complement(74801..76849) FT /transl_table=11 FT /gene="SCO1774" FT /gene_synonym="SCI51.14c" FT /product="putative regulatory protein" FT /note="SCI51.14c, probable regulatory protein, len: 682 aa; FT similar to the C-terminal region of other regulators from FT S.coelicolor e.g. SW:AFSR_STRCO (EMBL:D90155), AfsR, FT Streptomyces coelicolor global regulatory protein for FT secondary metabolite formation (993 aa), fasta scores; opt: FT 474 z-score: 505.1 E(): 8.8e-21, 27.7% identity in 656 aa FT overlap. The N-terminal and C-terminal regions of AfsR have FT been shown to direct actinorhodin production independently. FT The N-terminal half of this protein is also weakly similar FT to the C-terminal region of TR:Q9Z389 (EMBL:AL035654), FT CdaR, S.coelicolor transcriptional activator protein for FT CDA biosynthesis (592 aa) (28.6% identity in 332 aa FT overlap)" FT /db_xref="GOA:Q9S226" FT /db_xref="InterPro:IPR013026" FT /db_xref="UniProtKB/TrEMBL:Q9S226" FT /protein_id="CAB52838.1" FT /translation="MGSGVWPVTDQAVDTDGVRLSQDPDAESGFLGRTRELKELRADIE FT RAGLDTLSGRKAPRARVLLIAGRPGSGRTALAEELAARVAHDYPDGVLRARLSEPDGTR FT VPVEHLARELLTALERTAPPGADEDDLTEALRTALADRRALLLLDAVADAEQVDALLPD FT TPDCLAVAVAEGPLTGIADVRPCTLGGLDTKSAVELLSRHTGSVRITVDPRAAEQLVEL FT CQAQPAALTLAGGWLAARPQAAVADLAKHVHAESDETGALGRVFGLVYASLPGTAARML FT RLLSLAPAGLVDPHTASALAGCSVSGARTTLDDFVAHGLLRAVDSALPEYEVPGCLHGR FT LGALARKHDRPAELQLARARMLERTVRLLQSCRAVTETDSPQAREKLLATPRDLRFPHP FT RAAADWLRARRPALLAAARLAVADGELDTLARRLMSQLVRAMVAHFGTRAAAPDLYGIH FT RLVLDVAERRELPRERAAALLNLADLDARTGRTAEALVRYRAALDAGREAKDPYATGRA FT LESVGGAHLELGDYDRAADWFGRALAERLARDERADAARVYGRLATAHTYAGRYGEAVR FT AWRAAVSGHRKAGDVAAHARALAELARVQEYAGRPEESLRTCREAVDWARRAEDVRLQA FT ALHLRLADTLDRLGDPTAAGLERSAAERMLREDPADACEIRSTVSED" FT CDS complement(76998..77633) FT /transl_table=11 FT /gene="SCO1775" FT /gene_synonym="SCI51.15c" FT /product="conserved hypothetical protein" FT /note="SCI51.15c, conserved hypothetical protein, len: 211 FT aa; unknown function, similar to many bacterial FT hypothetical proteins e.g. TR:O33199 (EMBL:Z98268) FT Mycobacterium tuberculosis hypothetical protein (207 aa), FT fasta scores; opt: 508 z-score: 616.4 E(): 5.5e-27, 43.1% FT identity in 197 aa overlap. Contains Pfam match to entry FT PF00293 mutT, Bacterial mutT protein" FT /db_xref="GOA:Q9S225" FT /db_xref="HSSP:1MQE" FT /db_xref="InterPro:IPR000086" FT /db_xref="UniProtKB/TrEMBL:Q9S225" FT /protein_id="CAB52839.1" FT /translation="MTGSTIKDTPEEWEIRGSQTPFRGKKTSVRTDDVVMPDGSVVTRD FT YQVHPGSVAVLALDGEGRVLVIRQYRHPVREKLWEIPAGLLDVPGENPLHAAQRELYEE FT AHVKAEDWRVLTDVYTTPGGCDEAVRIFLARDLSEAAGERFEVEDEEADMELARVPVAD FT LVRGVLAGELHNNCLVVGVLALVAAERGDGLDALRPALAPWPARPFEA" FT misc_feature complement(77322..77444) FT /note="Pfam match to entry PF00293 mutT, Bacterial mutT FT protein, score 26.70, E-value 3.9e-06" FT CDS complement(77721..79370) FT /transl_table=11 FT /gene="SCO1776" FT /gene_synonym="SCI51.16c" FT /gene_synonym="pyrG" FT /product="putative CTP synthetase" FT /note="SCI51.16c, pyrG, probable CTP synthetase, len: 549 FT aa; highly similar to many CTP synthetases e.g. FT SW:PYRG_MYCTU (EMBL:Z98268, U88301), pyrG, Mycobacterium FT tuberculosis and Mycobacterium bovis CTP synthetase (586 FT aa), fasta scores; opt: 2622 z-score: 2909.4 E(): 0, 70.3% FT identity in 552 aa overlap. Contains PS00442 Glutamine FT amidotransferases class-I active site" FT /db_xref="GOA:Q9S224" FT /db_xref="InterPro:IPR000991" FT /db_xref="UniProtKB/Swiss-Prot:Q9S224" FT /protein_id="CAB52840.1" FT /translation="MPPKSSTTKHIFVTGGVASSLGKGLTASSLGMLLKARGLRVVMQK FT LDPYLNVDPGTMNPFQHGEVFVTNDGAETDLDIGHYERFLDRDLDGSANVTTGQVYSTV FT IAKERRGEYLGDTVQVIPHITNEIKHRIRRMATDEVDVVITEVGGTVGDIESLPFLETV FT RQVRHEVGRDNVFVVHISLLPYIGPSGELKTKPTQHSVAALRNIGIQPDAIVLRCDREV FT PTAIKRKISLMCDVDEAAVVACPDARSIYDIPKVIHTEGLDAYVVRRMDLPFRDVDWTT FT WDDLLDRVHNPEHEIVMALVGKYIDLPDAYLSVTEALRAGGFANKARVKIKWVTSDDCK FT TPAGARVQLGDVDAICIPGGFGERGVTGKVGAIQYARENGIPLLGLCLGLQCIVVEAAR FT NLAGVADANSTEFDPATAHPVVSTMAEQLDIVAGEGDMGGTMRLGMYPAKLAEGSIVRE FT VYDGKEYVEERHRHRYEVNNAYRAELEKKAGIVFSGTSPDGKLVEYVEYPRDVHPYLVA FT TQAHPELRSRPTRPHPLFAGLVKAAVERKTSK" FT misc_feature complement(78192..78227) FT /note="PS00442 Glutamine amidotransferases class-I active FT site" FT CDS 79920..81758 FT /transl_table=11 FT /gene="SCO1777" FT /gene_synonym="SCI51.17" FT /product="hypothetical protein" FT /note="SCI51.17, conserved hypothetical protein, len: 612 FT aa; unknown function, similar to TR:P71741 (EMBL:Z81368) FT Mycobacterium tuberculosis hypothetical protein (642 aa), FT fasta scores; opt: 1146 z-score: 1320.1 E(): 0, 40.6% FT identity in 623 aa overlap and SW:YAY3_SCHPO (EMBL:Z69380) FT Schizosaccharomyces pombe hypothetical protein (649 aa) FT (33.5% identity in 641 aa overlap). Also similar to FT SCE36.11C (EMBL:AL049763) S.coelicolor conserved FT hypothetical protein (fragment) (612 aa) (42.6% identity in FT 615 aa overlap)" FT /db_xref="GOA:Q9S223" FT /db_xref="InterPro:IPR011613" FT /db_xref="UniProtKB/TrEMBL:Q9S223" FT /protein_id="CAB52841.1" FT /translation="MRGDVAVRLELHVAGRIEDYALIGDMQTAALVCRDGTVDWLCLPR FT FDSHAIFAGLLGTGEHGFWRLGPAYAPGAEPPTSARRTYRGDSLILESEWDTPRGTVRV FT TDFMPPRDGAPQLIRIVEGVSGRVPMRSELRMRFSYGRVVPWVHKHEGRTVAVAGPDSV FT WFDTEAETYGKALTTYADFTVAPGDRVAFTISWEPSHKEPPALPEPEQSLVATEDFWRD FT WVEHCTYHGPYREAVVRSLITLKALTYAPTGGIVAAPTTSLPEDIGGVRNWDYRYTWLR FT DAAITLSSLLRTGYREEARAWREWLLRAVAGDPENLQIMYGIAGERELGEAELDWLPGY FT EGSGPVRVGNGAAHQLQLDVYGEVTEALHLGHMTGLARNDYASVLQLKLIRYLEDHWNE FT PDEGIWEVRGPRRHFVHSKVMAWVAVDRTIKLIESGDADGPLERWKQLRDDIHRDVCEK FT GYDKERNTFTQSYGSQALDASLLLIPQMGFLPPDDKRVIGTIEAIQRELSTSDGFILRY FT PTDGEAEGVDGLPGDEGAFLACSFWMADDLAMIGRVDEARKLFEKLLSLRNDLGLLAEE FT WDPRLQRQVGNFPQAFSHVPLIDTALRLTASGAYGG" FT CDS 82345..83991 FT /transl_table=11 FT /gene="SCO1778" FT /gene_synonym="SCI51.18" FT /product="putative transcriptional regulator" FT /note="SCI51.18, possible transcriptional regulator, len: FT 548 aa; shows weak similarity to TR:Q00509 (EMBL:X63451), FT SmrR, Streptomyces ambofaciens regulatory gene governing FT the expression of a polyketide synthase (604 aa), fasta FT scores; opt: 205 z-score: 220.9 E(): 5.9e-05, 26.5% FT identity in 460 aa overlap. Also similar to TR:O69807 FT (EMBL:AL023496) Streptomyces coelicolor hypothetical FT protein (537 aa) (32.4% identity in 547 aa overlap) and FT PkwR (EMBL:AF115313) Thermomonospora curvata putative FT regulatory protein (535 aa) (28.8% identity in 534 aa FT overlap). Contains probable helix-turn-helix motif at aa FT 498-519 (Score 1712 (+5.02 SD)" FT /db_xref="InterPro:IPR012914" FT /db_xref="UniProtKB/TrEMBL:Q9S222" FT /protein_id="CAB52842.1" FT /translation="MDSGTNSGFDTQGAGITVRRALELPGLRSGLPEILAGADRMQRTV FT RWVHAGEVPNIASLLKGGELLLTTGYGLGTRPAEQRAFVRTLAERGIAALVVELGPRFT FT RLPAALVDTARAAGLPLVQLHREVPFVAVTEEIHTEIVNGHYALLQRAEEVHRRCTEAL FT LGGGGVPQVLAILADFAGNPVFLETTDGRLLYAAGAGPEGADPLQVWEGLRDPHKDAPP FT PAGSVLVDVPGGGPGTGSVRARLVLLPVRSSPAPVHRMAAERAAGILAVVLMQARQEEE FT LAARGRGDFLTDLAEGRITAEDAPAQARVLGFKPGAGPLLPVVMRLGDALSPAGGGWAV FT LARAVAEELASVGVPVLLGVRPVEGRVPLLLGLRSESERAAVADRVAVALRAGVERAGI FT RRPGAQPPVVVVGVSGGWAAASAGLRHAAETATAAQGLTDRPWYDARRLDIDLLLWRLR FT DHPDLAAFVDRAIGPLRDHDDRSKPPLLPTLQTYLAHACRKAETARELHLNRQTLYNRL FT ARIGELLGTDLDDPQTVLALSLALRARRHVP" FT CDS complement(84014..85219) FT /transl_table=11 FT /gene="SCO1779" FT /gene_synonym="SCI51.19c" FT /product="hypothetical protein" FT /note="SCI51.19c, hypothetical protein, len: 401 aa; FT unknown function, C-terminus shows weak similarity to FT SW:YPJH_BACSU (EMBL:L47709), YpjH, Bacillus subtilis FT hypothetical protein (377 aa), fasta scores; opt: 211 FT z-score: 223.0 E(): 1e-05, 28.0% identity in 193 aa FT overlap. Shows similarity to TR:Q9Z5B7 (EMBL:AL035478) FT S.coelicolor possible transferase (402 aa) (31.9% identity FT in 407 aa overlap). Contains Pfam match to entry PF00534 FT Glycos_transf_1, Glycosyl transferases group 1" FT /db_xref="GOA:Q9S221" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q9S221" FT /protein_id="CAB52843.1" FT /translation="MTVPTSFVTVPRRTRSPGQVTPVSSHSPHGQSPLRTVQVLGGGNA FT GSSAHVRSLAAGLVARGVKVTVCAPSDAECTYDFTGAGADHVHVPRSSDPVSVAALRTV FT CAEADLVHAHGLHASFRAALALGGRRVRTPLVVTWHDRAHAEGARGQLLRVLERRVMKA FT ATVVLGATSELVDGARRTGARDARLGPVALPARPGPPAGSDDPDPLRPKVRAELGAIDR FT PLLVAVGSLERHRGYDVLLDAARVWRRLDPAPLVVVAGEGPLRGELQGRIEGEGLPVVL FT VGSRDDVPDLLAAADLALLLSRREPGRSVLAQEALHARVPLVAGAVGGIPELVGDAAEL FT VPPGDAAALADAVVRLLADPARQDELRERGTRQAATWPTEDETVAQVLSIYDELTQPTP FT LL" FT misc_feature complement(84101..84547) FT /note="Pfam match to entry PF00534 Glycos_transf_1, FT Glycosyl transferases group 1, score 49.80, E-value FT 4.1e-13" FT CDS complement(85490..87208) FT /transl_table=11 FT /gene="SCO1780" FT /gene_synonym="SCI51.20c" FT /product="putative DNA repair protein" FT /note="SCI51.20c, possible DNA repair protein, len: 572 aa; FT similar to SW:RECN_ECOLI (EMBL:Y00357), recN, Escherichia FT coli DNA repair protein (553 aa), fasta scores; opt: 425 FT z-score: 428.6 E(): 3.6e-17, 33.1% identity in 568 aa FT overlap and to recN homologues. Contains probable FT coiled-coils from 155 to 189 (35 residues) (Max score: FT 1.472, probability 0.91) and from 336 to 376 (41 residues) FT (Max score: 1.517, probability 0.96). Contains PS00017 FT ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9S220" FT /db_xref="InterPro:IPR004604" FT /db_xref="UniProtKB/Swiss-Prot:Q9S220" FT /protein_id="CAB52844.1" FT /translation="MRIRSLGVIDDAVVELSPGFTAVTGETGAGKTMVVTSLGLLLGGR FT ADAALVRIGAKNAVVEGRIAVPGDAAVAVRAEEAGAELDDGALLISRTVSAEGRSRAHL FT GGRSVPVGMLAELADELVAVHGQTDQQGLLKLNRQRQALDRYAGDAVAGPLAKYAEAYR FT RLRAVVRELEEITTRARERAQEADLLRYGLDEIAAVEPRAGEDVELAEEAERLGHAEAL FT ASAATVAHAALAGNPEDPEGVDGATLVAGAQRALDAVRSHDPALAALAERIGEVGILLR FT DVAGELAGYADDLDADPLRLAAVEERRAALTALTRKYGEDIAAVLSWAEQSAARLTELD FT GDDERIGELTAERDALRAELGGLAQALTDARTEAAERFAAAVTAELASLAMPHARVSFA FT IRQTEDPEGVEIGGRTVAYGPSGADEVELLLAPHPGAPARPIAKGASGGELSRVMLAVE FT VVFAGTDPVPTYLFDEVDAGVGGKAAVEIGRRLARLARSAQVVVVTHLPQVAAFADRQL FT LVEKTNDGSVTRSGVKVLEGEERVRELSRMLAGQEDSETARAHAEELLETARADR" FT misc_feature complement(87113..87136) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(87373..88278) FT /transl_table=11 FT /gene="SCO1781" FT /gene_synonym="SCI51.21c" FT /gene_synonym="ppnK" FT /product="inorganic polyphosphate/ATP-NAD kinase" FT /note="SCI51.21c, probable inorganic polyphosphate/ATP-NAD FT kinase, len: 301 aa; similar to many bacterial hypothetical FT proteins e.g. TR:O33196 (EMBL:Z98268) Mycobacterium FT tuberculosis hypothetical protein (307 aa), fasta scores; FT opt: 975 z-score: 1090.7 E(): 0, 53.6% identity in 302 aa FT overlap. Highly similar to SW:PPNK_MYCTU (EMBL:AB044336) FT Mycobacterium tuberculosis inorganic polyphosphate/ATP-NAD FT kinase (EC 2.7.1.23) (poly(P)/ATP NAD kinase) PpnK, 307 aa; FT fasta scores: opt: 975 Z-score: 1068.4 E(): 7e-52; 53.642% FT identity in 302 aa overlap" FT /db_xref="GOA:Q9S219" FT /db_xref="InterPro:IPR002504" FT /db_xref="UniProtKB/Swiss-Prot:Q9S219" FT /protein_id="CAB52845.1" FT /translation="MTQNRVRTVFLLAHTGRPAAIRSAELVVKGLLRAGIGVRVLEAEA FT RDLPLPGEVELVGEATPQCLDGCELLIVLGGDGTLLRGAEFARASGVPMLGVNLGRVGF FT LAEAERDDLDKVVDRVVNRAYEVEERMTVDVVVHRNGDIVHTDWALNEAAVQKAGAEKL FT LEVVLEIDGRPVTGFGCDGIVLSTPTGSTAYAFSAGGPVVWPEVEALLMVPISAHALFA FT KPLVTSPDSVLAVEVLPHVPPGVLWCDGRRTVELPPGARVEVRRGAVPVRLARLHHASF FT TDRLVAKFALPVSGWRGAPH" FT CDS complement(88275..89090) FT /transl_table=11 FT /gene="SCO1782" FT /gene_synonym="SCI51.22c" FT /product="putative membrane protein" FT /note="SCI51.22c, possible membrane protein, len: 271 aa; FT unknown function, similar to hemolysins and hemolysin-like FT hypothetical proteins e.g. SW:HLYA_TREHY (EMBL:X61684), FT tlyA, Treponema hyodysenteriae hemolysin A (240 aa), fasta FT scores; opt: 457 z-score: 532.9 E(): 2.5e-22, 35.4% FT identity in 240 aa overlap and TR:Q50760 (EMBL:X98295), FT tlyA, Mycobacterium tuberculosis. Contains a hydrophobic, FT possible membrane-spanning region. Contains Pfam match to FT entry PF01479 S4, S4 domain and PS00017 ATP/GTP-binding FT site motif A (P-loop)" FT /db_xref="GOA:Q9S218" FT /db_xref="InterPro:IPR002877" FT /db_xref="UniProtKB/TrEMBL:Q9S218" FT /protein_id="CAB52846.1" FT /translation="MAGVARRRLDAELVRRKLARSREHASQLIAAGRVTVGKTVATKPA FT TQVETAAAIVVTADDNDPDYVSRGGHKLAGALAAFVPHGLVVEGRRALDAGASTGGFTD FT VLLRAGAAHVVAVDVGYGQLAWSLRQDERVTVKDRTNVRELTPEAIDGEPVDLVVGDLS FT FIPLALVLPALVRCTRPGADLVMMVKPQFEVGKERLGSGGVVRSAQLRAEAVRGVARKA FT WELGLGVKGVTASPLPGPSGNVEYFLWLRAGAGELDPADVDRAVAEGPR" FT RBS complement(88286..88290) FT /note="possible RBS" FT misc_feature complement(88884..89072) FT /note="Pfam match to entry PF01479 S4, S4 domain, score FT 51.20, E-value 2.2e-11" FT misc_feature complement(88974..88997) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(89098..89445) FT /transl_table=11 FT /gene="SCO1783" FT /gene_synonym="SCI51.23c" FT /product="hypothetical protein" FT /note="SCI51.23c, hypothetical protein, len: 115 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. The FT C-terminus is Pro-rich" FT /db_xref="UniProtKB/TrEMBL:Q9S217" FT /protein_id="CAB52847.1" FT /translation="MSDAVPEPEPQREPVAGAEAAEPGADTGPGYEPAAPAPLDVPRDP FT TGNTEVDARLARLADADHLATDGHVEVYEDVHRGLRDALTALDARPGPPEPPGRPGPPA FT PPPPSPYDRRS" FT CDS 89488..89835 FT /transl_table=11 FT /gene="SCO1784" FT /gene_synonym="SCI51.24" FT /product="hypothetical protein" FT /note="SCI51.24, hypothetical protein, len: 115 aa; unknown FT function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition" FT /db_xref="UniProtKB/TrEMBL:Q9S216" FT /protein_id="CAB52848.1" FT /translation="MATTEECRAALDKLSDTMRGAEGDVRSATELDRSVSCHITDLDVT FT FAGRMADGRIDVRETLEGPPRERAEIRLAMTGDDLVALVAGELNFARAWGSGRVKLEAG FT LRDLLRLRKLL" FT CDS complement(89819..90724) FT /transl_table=11 FT /gene="SCO1785" FT /gene_synonym="SCI51.25c" FT /product="putative iron-siderophore uptake system FT ATP-binding component" FT /note="SCI51.25c, probable iron-siderophore uptake system FT ATP-binding component, len: 301 aa; similar to many FT ATP-binding components from binding-protein-dependent iron FT uptake systems using a range of siderophores e.g. FT SW:FEPC_ECOLI (EMBL:X57471), fepC, Escherichia coli ferric FT enterobactin transport ATP-binding protein (271 aa), fasta FT scores; opt: 1101 z-score: 1184.4 E(): 0, 61.5% identity in FT 260 aa overlap. Similar to other binding-protein-dependent FT permease subunits e.g. SC9B1.09 (EMBL:AL049727) FT S.coelicolor putative ABC transporter ATP-binding subunit FT (386 aa) (37.7% identity in 228 aa overlap). Contains Pfam FT match to entry PF00005 ABC_tran, ABC transporter, PS00211 FT ABC transporters family signature and PS00017 FT ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9S215" FT /db_xref="HSSP:1L7V" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9S215" FT /protein_id="CAB52849.1" FT /translation="MSAGTGHRSGPNNRRSNSNVNRLTAENVTLAYDQRVIAEKLSVEI FT PDNSFTVIVGPNACGKSTLLRALSRMLRPSQGRVLLDGSVIQSMPAKQVARTLGLLPQS FT SIAPDGITVGDLVGRGRYPHQGILRQWSTEDERVVQESMARTGISELADRYVDELSGGQ FT RQRVWIAMALAQQTPLLLLDEPTTYLDIQHQIDVLDLCAELHEEQGRTLVAVLHDLNHA FT ARYATHLIALREGQVIAEGAPKDIVTADLVERVFGLRCQVIDDPETGTPLVVPAARKGR FT TKQVNEQVTEQAKAVATGAS" FT misc_feature complement(90020..90583) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 183.60, E-value 3.2e-51" FT misc_feature complement(90206..90250) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(90539..90562) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(90721..91848) FT /transl_table=11 FT /gene="SCO1786" FT /gene_synonym="SCI51.26c" FT /product="putative iron-siderophore uptake system FT transmembrane component" FT /note="SCI51.26c, probable iron-siderophore uptake system FT transmembrane component, len: 375 aa; similar to many FT transmembrane components from binding-protein-dependent FT iron uptake systems using a range of siderophores e.g. FT SW:FEPG_ECOLI (EMBL:X57471), fepG, Escherichia coli ferric FT enterobactin transport protein (330 aa), fasta scores; opt: FT 946 z-score: 1034.3 E(): 0, 50.0% identity in 310 aa FT overlap. Similar to neighbouring SCI51.27c, probable FT iron-siderophore uptake system transmembrane component (348 FT aa) (37.9% identity in 348 aa overlap). Contains FT hydrophobic, possible membrane-spanning regions. Contains FT Pfam match to entry PF01032 FecCD_family, FecCD transport FT family" FT /db_xref="GOA:Q9S214" FT /db_xref="HSSP:1L7V" FT /db_xref="InterPro:IPR000522" FT /db_xref="UniProtKB/TrEMBL:Q9S214" FT /protein_id="CAB52850.1" FT /translation="MKTAKNGKTAKTAKTAKTVKYGKTVKYGKTVKRVRAVRTPGGLSL FT RLDVRAAVVVALLLLLALAASVLLIGTGDFDIPAVDVLKTLVGQGNAGQEFIVNELRLP FT RVLVGLLVGAALGVGGALFQAISRNPLGSPDVLGLGQGATAGALIMIVLFSGSSAQVTV FT GALVGGLVTGLAIYLLAWKRGVHGYRLVLVGIGVSAIVTAVNGYLLTRADIVDASRAVV FT WMTGSLNGRDWDQVWPLLALCAVLVPLVLTNGRALRMMEMGDDVSYALGVRVERVRALL FT MVAAVLLTAAATAAAGPVSFVALTAPQLARRLTRSPGPNLLPSLCMGAALLVGADWISQ FT RVFGAEQLPVGVVTGVLGGVYLLWLLVTERKAGRI" FT misc_feature complement(90745..91632) FT /note="Pfam match to entry PF01032 FecCD_family, FecCD FT transport family, score 351.20, E-value 1.1e-101" FT CDS complement(91845..92891) FT /transl_table=11 FT /gene="SCO1787" FT /gene_synonym="SCI51.27c" FT /product="putative iron-siderophore uptake system FT transmembrane component" FT /note="SCI51.27c, probable iron-siderophore uptake system FT transmembrane component, len: 348 aa; similar to many FT transmembrane components from binding-protein-dependent FT iron uptake systems using a range of siderophores e.g. FT SW:FEPD_ECOLI (EMBL:X57471), fepD, Escherichia coli ferric FT enterobactin transport protein (334 aa), fasta scores; opt: FT 910 z-score: 991.5 E(): 0, 46.0% identity in 326 aa FT overlap. Similar to neighbouring SCI51.26c, probable FT iron-siderophore uptake system transmembrane component (375 FT aa) (37.9% identity in 348 aa overlap). Contains FT hydrophobic, possible membrane-spanning regions. Contains FT Pfam match to entry PF01032 FecCD_family, FecCD transport FT family" FT /db_xref="GOA:Q9S213" FT /db_xref="HSSP:1L7V" FT /db_xref="InterPro:IPR000522" FT /db_xref="UniProtKB/TrEMBL:Q9S213" FT /protein_id="CAB52851.1" FT /translation="MLVDSPPEQRAETAPAPPSKRRVLRAAGLPVSVAALVLIVLASIA FT IGAKDLSLAEVWHGLFHDSGTYGDVVVGERLSRTVLGLLAGAALGLAGAVLQALTRNPL FT ADPGLLGINAGASAAVVTGITFFGVTSLTGYVWFAFAGAAGVGALVWFLGGSRGATPVR FT LVLAGTAISAALFGYLQAVMIMDDAALGRMRFWTVGSLASATTGTIREVLPFFVVGTVL FT ALALARPLNAMEMGDDTAKALGANLNRTRALSMLAATVLCGAATAACGPIVFVGLMIPH FT IVRSFTGPDMRWILPYAAILSPVLLLGADVLGRIVARPSELQVGIITAVLGGPVFIFLV FT RRRRTAQL" FT RBS complement(91860..91864) FT /note="possible RBS" FT misc_feature complement(91866..92753) FT /note="Pfam match to entry PF01032 FecCD_family, FecCD FT transport family, score 368.20, E-value 8.7e-107" FT CDS complement(93036..94067) FT /transl_table=11 FT /gene="SCO1788" FT /gene_synonym="SCI51.28c" FT /product="conserved hypothetical protein" FT /note="SCI51.28c, conserved hypothetical protein, len: 343 FT aa; unknown function, similar to other hypothetical FT proteins e.g. TR:O33194 (EMBL:Z98268) Mycobacterium FT tuberculosis hypothetical protein (353 aa), fasta scores; FT opt: 768 z-score: 825.7 E(): 0, 44.8% identity in 315 aa FT overlap, with SCI51.28c. Also shows weak similarity to FT SW:NAGD_ECOLI (EMBL:X14135), nagD, a CDS in the Escherichia FT coli N-acetylglucosamine operon (250 aa) (26.7% identity in FT 243 aa overlap) and to SW:PNPP_SCHPO (EMBL:X62722) FT Schizosaccharomyces pombe 4-nitrophenylphosphatase (unknown FT physiological substrate) (269 aa) (27.7% identity in 238 aa FT overlap)" FT /db_xref="GOA:Q9S212" FT /db_xref="InterPro:IPR006357" FT /db_xref="UniProtKB/TrEMBL:Q9S212" FT /protein_id="CAB52852.1" FT /translation="MSRSVRTRPAGSGPDLSEAYDTALLDLDGVVYAGGNAIAHAVDSL FT AAARDGGMRLAYVTNNALRTPDAVAAHLTELGIPTGAEDVVTSAQAVARLMAEQLPSGA FT RVLVIGGEGLRVALRERGLEPVESAEDDPAAVVQGFGGPELPWGRFAEACYAIERGVPW FT YASNTDLTIPGARGIAPGNGAAVEVVRIATGAEPQVAGKPLPPMHRETILRTGARRPLV FT VGDRLDTDIEGAFNGEVDSLLVLTGVTDGAQLLAAAPQHRPTYVDADLRGLLTGQPEVT FT GDAEGGFRCGGWTATAGGERLELDGDGAALDGLRVLCAAAWTAGGEQGCGLDSGKALAR FT LGW" FT RBS complement(94077..94081) FT /note="possible RBS" FT CDS 94140..95432 FT /transl_table=11 FT /gene="SCO1789" FT /gene_synonym="SCI51.29" FT /product="hypothetical protein" FT /note="SCI51.29, hypothetical protein, len: 430 aa; unknown FT function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition" FT /db_xref="InterPro:IPR008323" FT /db_xref="UniProtKB/TrEMBL:Q9S211" FT /protein_id="CAB52853.1" FT /translation="MNSAGHPEATARRGLELTPFRGLRYDPDRVGSLAAVTSPPYDVVV FT RPDGLLHLESADPYNIVRLILPQAATPEARNEQAARTLRRWTAEGVLTTDPDPGLYVYE FT QRDREGMLQRGIIGALRVSDPSEQVVLPHEDVMPHVVADRAALMRATRANLEPLLLTYR FT GDDATPATPALVERTAEQPPLLSTTTEDGFCHRLWSVTAPDTVARVRAELSRHQALIAD FT GHHRWATYRTLRAEHPSPSPWDHGLVLLVDTARYPLRVRAIHRLLHGVPVHEAVAALAG FT HFRVRRLGTSLDESLETLAKAAGSGNAFLLAGDGAFHLVDLPDPGLLARTVPTDRPEAW FT RTLDATVLHATLLAHVWHVPDDSASHISYIHDTAATVEKAERDGGTAVLMHPVREEVVR FT ELARQGVTMPRKSTSFGPKPASGLVLRPLDA" FT CDS complement(95518..96150) FT /transl_table=11 FT /gene="SCO1790" FT /gene_synonym="SCI51.30c" FT /product="conserved hypothetical protein" FT /note="SCI51.30c, conserved hypothetical protein, len: 210 FT aa; unknown function, similar to part of TR:O33193 FT (EMBL:Z98268) Mycobacterium tuberculosis hypothetical FT protein (250 aa), fasta scores; opt: 560 z-score: 665.7 FT E(): 1e-29, 49.7% identity in 185 aa overlap. The start FT codon is uncertain" FT /db_xref="GOA:Q9S210" FT /db_xref="InterPro:IPR011990" FT /db_xref="UniProtKB/TrEMBL:Q9S210" FT /protein_id="CAB52854.1" FT /translation="MMVARLLDEDPEAAYGYSRVALRLASRVAAVREAAGFAAYANQKY FT AEALAEFRAARRMTGSVELWPVMADCERGLGRPEKALDMAGAPEVHKLDKAGQVEMRLV FT AAGARRDMGQLDAAIVTLQSPELASNSVQPWTARLRYAYADALLAAGREQEAREWFAKA FT VESDRDGSTDASDRLAELDGVEFMDALDEGESESDGQRPAAEDGDED" FT CDS complement(96147..97406) FT /transl_table=11 FT /gene="SCO1791" FT /gene_synonym="SCI51.31c" FT /product="hypothetical protein" FT /note="SCI51.31c, hypothetical protein, len: 419 aa; FT unknown function, improbable CDS containing Thr- and FT Val-rich repeats and having a Ser- and Arg-rich C-terminus. FT Due to the unusual base composition in this region this FT assignment should be treated with caution" FT /db_xref="UniProtKB/TrEMBL:Q9S209" FT /protein_id="CAB52855.1" FT /translation="MTCGTEDRSHPCPPTLPTTDRSATSADGTVVTVATAGISAGTAVG FT SAETTVGATTVADSAVASVVTTETVGRVGTIAIVVATGVSVAMTGVVTVRPSAATTVVS FT VGTGATVPRTVATTAESVVTAPPSVGTIAVMTVVTIGAMTAVGSAAASVVTTVGMTAVM FT TAATVVARTTAVPATGVGTTGTVAATGASVAMTGVVTVRPSAATTVVSVGTGATVPRTV FT ATTGVTVPRTGGMTAVTTVGMTVLPSGAMTVGMTVLPSGAMTGVTSAVTTVLPSGVTTG FT AMTAVTTVLPSGVTTAVTTVAIVVASGGTTTVVSAADSADATTAGVVTVVGSVGVTTAE FT AAGPVEMTAEGGPAATGAVTTGRAAVAVSATSATVTGTGSRSSGCRSPRRSRATRSTRT FT CGRSCRACPRRSRRTSPGTW" FT repeat_region complement(96499..96708) FT /note="repeat 1; approx. 15x degenerate direct repeats" FT repeat_region complement(96721..96871) FT /note="repeat 4; degenerate 151 bp direct repeat" FT repeat_region complement(96894..96949) FT /note="repeat 2; approx. 4x degenerate direct repeats, same FT repeating element as repeat 1" FT repeat_region complement(96969..97024) FT /note="repeat 3; approx. 4x degenerate direct repeats, same FT repeating element as repeat 1" FT repeat_region complement(97042..97192) FT /note="repeat 4; degenerate 151 bp direct repeat" FT stem_loop complement(97447..97491) FT /note="stem, 20/20 (100%) matches, 0 gaps; loop, 5 bp" FT rRNA complement(97501..97621) FT /gene="rrnB" FT /note="probable 5S rRNA, coordinates taken from similarity FT to Streptomyces rimosus 5S rRNA gene of the rrnF gene set FT (EMBL:X62884)" FT rRNA complement(97723..100845) FT /gene="rrnB" FT /note="probable 23S rRNA, coordinates taken from similarity FT to Streptomyces rimosus 23S rRNA gene of the rrnF gene set FT (EMBL:X62884)" FT rRNA complement(101122..102649) FT /gene="rrnB" FT /note="probable 16S rRNA, coordinates taken from similarity FT to Streptomyces rimosus 16S rRNA gene of the rrnF gene set FT (EMBL:X62884)" FT CDS complement(103178..103819) FT /transl_table=11 FT /gene="SCO1792" FT /gene_synonym="SCI51.32c" FT /product="putative DNA glycosylase" FT /note="SCI51.32c, possible 3-methyladenine DNA glycosylase, FT len: 213 aa; similar to several eukaryotic 3-methyladenine FT DNA glycosylases, but shorter at the N-terminus e.g. FT SW:3MG_HUMAN (EMBL:M74905) Homo sapiens (Human) FT DNA-3-methyladenine glycosylase (298 aa), fasta scores; FT opt: 410 z-score: 485.1 E(): 1.1e-19, 38.6% identity in 207 FT aa overlap. Also similar putative 3-methyladenine DNA FT glycosylases from mycobacteria e.g. SW:3MGH_MYCTU FT (EMBL:Z98268) Mycobacterium tuberculosis possible FT 3-methyladenine DNA glycosylase (203 aa) (43.0% identity in FT 193 aa overlap)" FT /db_xref="GOA:Q9S208" FT /db_xref="HSSP:1EWN" FT /db_xref="InterPro:IPR003180" FT /db_xref="UniProtKB/Swiss-Prot:Q9S208" FT /protein_id="CAB52856.1" FT /translation="MIASPDRTPLPREFFDRPVLEVAPDLLGRILVRTGPDGPITLRLT FT EVEAYDGQNDPGSHAYRGRTPRNEVMFGPPGHVYVYFTYGMWFCMNLVCGPEGRSSAVL FT LRAGEIIDGAELARTRRLSARNDKELAKGPARLATALGVDRALNGTDACTSQETPLRIL FT TGTPVPGDQVRNGPRTGVAGEGGVHPWRYWVADDPTVSPYRAHVPRKRRS" FT CDS 103966..104748 FT /transl_table=11 FT /gene="SCO1793" FT /gene_synonym="SCI5.01" FT /gene_synonym="SCI51.33" FT /product="putative secreted protein" FT /note="SCI5.01, partial CDS, unknown, len: >195aa; similar FT to TR:O87735 (EMBL:D89936) sporulation control protein FT Spo0M from Bacillus subtilis (258 aa) fasta scores; opt: FT 283, z-score: 342.4, E(): 9.7e-12, (32.7% identity in 153 FT aa overlap)." FT /note="SCI51.33, hypothetical protein, partial CDS, len: FT >98 aa; unknown function, similar to TR:O87735 FT (EMBL:D89936), Spo0M, Bacillus subtilis sporulation-control FT protein (258 aa), fasta scores; opt: 214 z-score: 268.2 FT E(): 1.4e-07, 34.8% identity in 92 aa overlap. Continues in FT cosmid I5 as SCI5.01 (EMBL:AL079332) S.coelicolor FT hypothetical protein (195 aa). Contains possible N-terminal FT region signal peptide sequence" FT /db_xref="InterPro:IPR009776" FT /db_xref="UniProtKB/TrEMBL:Q8CK18" FT /protein_id="CAD55178.1" FT /translation="MAFKKLLASLGAGGASVETVLSESNVVPGGVVQGEVRIQGGSVDQ FT EIEGLSVGLQAKVEVESGDQEYKQDVEFTKVRLGGAFQLKAGVVHAVPFGLEIPWETPI FT TMIDGQALRGMNIGVTTELEIARAVDSGDLDAINVHPLPAQKAILDAFIGLGFRFKSAD FT MERGHIRGTRQQLPFYQEIEFFPPQQYRGLNQVELSFVADAQAMDVVLEMDKKPGLFSE FT GSDTFRSFKVGLNDYQGTDWTAYLNQWLSEVGSKRNWF" FT CDS 104800..105339 FT /transl_table=11 FT /gene="SCO1794" FT /gene_synonym="SCI5.02" FT /product="conserved hypothetical protein" FT /note="SCI5.02, conserved hypothetical protein, len: 179 FT aa; similar to many eg. TR:O06235 (EMBL:Z95388) FT hypothetical protein from Mycobacterium tuberculosis (176 FT aa) fasta scores; opt: 581, z-score: 658.0, E(): 2.6e-29, FT (52.9% identity in 172 aa overlap)" FT /db_xref="HSSP:1FUX" FT /db_xref="InterPro:IPR005247" FT /db_xref="UniProtKB/Swiss-Prot:Q9X9Z8" FT /protein_id="CAB45286.1" FT /translation="MTELKRRPLPHDFHPPVPSFTVTSEDVPEGGTLKDDQVHAAGNTS FT PHLRWEGFPAETKSFAVTCYDPDAPTGSGFWHWVVFDIPASVTELPVGAGSGAFEGLPQ FT GAVQARNDYGSKGFGGAAPPPGDGPHRYVFTVYAVDQEKLGPDADGTPAFVGFNLRFHT FT IARAHLISEYEVPADS" FT CDS 105496..106002 FT /transl_table=11 FT /gene="SCO1795" FT /gene_synonym="SCI5.03" FT /product="conserved hypothetical protein" FT /note="SCI5.03, unknown, len: 168 aa; similar to TR:P72833 FT (EMBL:D90901) hypothetical protein from Synechocystis sp. FT PCC6803 (165 aa) fasta scores; opt: 417, z-score: 517.5, FT E(): 1.7e-21, (46.9% identity in 143 aa overlap)" FT /db_xref="GOA:Q9X9Z7" FT /db_xref="InterPro:IPR003615" FT /db_xref="UniProtKB/TrEMBL:Q9X9Z7" FT /protein_id="CAB45287.1" FT /translation="MRDTLVLNASFEPLSTVTLNRAVVLVLQDKAVVEQAHPSLRMRGA FT ALDIPAPRVIRLCQYVRVPFRRRAPWSRRGVLVRDRHRCAYCGRRATTVDHVVPRSHGG FT QDTWLNTVASCAEDNHRKANRTPEQAGMPLLRKPFEPTPADAMLLALARDDFAALPEWL FT VLDAA" FT CDS complement(106144..107103) FT /transl_table=11 FT /gene="SCO1796" FT /gene_synonym="SCI5.04c" FT /product="putative secreted protein" FT /note="SCI5.04c, putative secreted protein, len: 319 aa; FT similar to many e.g. SW:YS09_MYCTU hypothetical protein FT from Mycobacterium tuberculosis (381 aa) fasta scores; opt: FT 956, z-score: 915.0, E(): 0, 55.3% identity in 311 aa FT overlap. Contains Pfam match to PF01145 and Prosite match FT to PS01270 Band 7 protein family signature. Contains FT possible N-terminal region signal peptide sequence" FT /db_xref="GOA:Q9X9Z6" FT /db_xref="InterPro:IPR018080" FT /db_xref="UniProtKB/TrEMBL:Q9X9Z6" FT /protein_id="CAB45288.1" FT /translation="MEPVIIVLIILVVLVFIALIKTIQVIPQASAAIVERFGRYTRTLN FT AGLNIVVPFIDTIRNRIDLREQVVPFPPQPVITQDNLVVNIDTVIYYQVTDARAATYEV FT ASYIQAIEQLTVTTLRNIIGGMDLERTLTSREEINAALRGVLDEATGKWGIRVNRVELK FT AIEPPTSIQDSMEKQMRADRDKRAAILQAEGVRQSEILRAEGEKQSQILRAEGEAKAAA FT LRAEGEAQAVRTVFEAIHAGDPDQKLLSYQYLQMLPKIAEGDANKLWIVPSEIGDALKG FT LSGAMGNFGGLGGGSGTGGGNGGASLPAQERREKPSID" FT repeat_region 106410..106550 FT misc_feature complement(106510..107082) FT /note="Match to PF01145 Score 316.41." FT misc_feature complement(106615..106701) FT /note="PS01270 Band 7 protein family signature." FT CDS complement(107281..107712) FT /transl_table=11 FT /gene="SCO1797" FT /gene_synonym="SCI5.05c" FT /product="putative integral membrane protein" FT /note="SCI5.05c, possible integral membrane protein, len: FT 143aa; similar to TR:P71767 (EMBL:Z79701) hypothetical FT protein from Mycobacterium tuberculosis (144 aa) fasta FT scores; opt: 344, z-score: 409.3, E(): 1.8e-15, (44.8% FT identity in 134 aa overlap). Contains possible membrane FT spanning hydrophobic regions." FT /db_xref="InterPro:IPR002810" FT /db_xref="UniProtKB/TrEMBL:Q9X9Z5" FT /protein_id="CAB45289.1" FT /translation="MNDIDAWVWWLVAAAALGIPLVVTAMPEFGMFAVGAVAAAVASGL FT GADLVVQVLVFVIVSVALIAVVRPIAARHRSQQPQLATGVDALKGRQAVVLERVDGAGG FT RIKLAGEIWSARALDTGRAFEPGEEVDVVEIDGATAVIM" FT CDS complement(107767..108564) FT /transl_table=11 FT /gene="SCO1798" FT /gene_synonym="SCI5.06c" FT /product="putative ABC transporter ATP-binding subunit" FT /note="SCI5.06c, possible ABC transporter ATP-binding FT subunit, len: 265aa; similar to many egs. TR:O53288 FT (EMBL:AL021287) predicted ABC transporter ATP-binding FT subunit (287 aa) fasta scores; opt: 893, z-score: 998.3, FT E(): 0, (53.3% identity in 257 aa overlap) and FT SW:LIVG_SALTY high-affinity branched-chain amino acid FT transporter from Salmonella typhimurium (255 aa) fasta FT scores; opt: 343, z-score: 390.2, E(): 2.1e-14, (31.0% FT identity in 248 aa overlap). Contains Pfam match to PF00005 FT ABC transporter transmembrane region and Prosite match to FT PS00017 ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q9X9Z4" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9X9Z4" FT /protein_id="CAB45290.1" FT /translation="MSDVLELQDVTVVREGRALVDQVSWSVKEGERWVILGPNGAGKTT FT LLNVASSYLYPSSGTATILGETLGRPGTDVFELRPRIGVAGIAMADKLPKRQTVLQTVL FT TAAYGMTAGWQEEYEDIDEQRARAFLDRLGMTEYLDRRFGTLSEGERKRTLIARALMTD FT PELLLLDEPAAGLDLGGREDLVRRLGRLARDPIAPSMIMVTHHVEEIAPGFTHVLMIRQ FT GQVLAAGPLELELTSRNLSLCFGLPLIVEQAGDRWTAKGLPLS" FT misc_feature complement(107896..108477) FT /note="Match to PF00005 ABC transporter transmembrane FT region Score 160.89." FT misc_feature complement(108433..108456) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 108718..109497 FT /transl_table=11 FT /gene="SCO1799" FT /gene_synonym="SCI5.07" FT /product="hypothetical protein" FT /note="SCI5.07, unknown, len: 259 aa; similar to FT SW:YS07_MYCTU hypothetical protein from Mycobacterium FT tuberculosis (302 aa) fasta scores; opt: 131, z-score: FT 146.5, E(): 0.79, (32.3% identity in 279 aa overlap)." FT /db_xref="UniProtKB/TrEMBL:Q9X9Z3" FT /protein_id="CAB45291.1" FT /translation="MLSEPRAGRLAAWGNALIAHMVSPDDAAVAIVGEDAVHRVEGLPG FT EAAPVGLTLALGRLRALGAVGLRIALPAPGHPLGLSGPPEFNARALEAEEAVICEGAAL FT GLVPEVYEAGPEGDVHVEVVWHCLPVREAPPADVPSLGEAERELAEALRDATEVLTRLD FT VAGSGPVAEAAVAAYRARAERGREVLAPGYPPRAVRVLELAQRVGVLVSLASENGHGGA FT VSASEMVARGEALRPVERVARRAQVAAYNSVVVERGR" FT CDS complement(109643..109891) FT /transl_table=11 FT /gene="SCO1800" FT /gene_synonym="SCI5.08c" FT /product="putative small secreted protein" FT /note="SCI5.08c, possible small secreted protein, len: FT 82aa; contains possible N-terminal signal sequence." FT /db_xref="InterPro:IPR005528" FT /db_xref="UniProtKB/TrEMBL:Q9X9Z2" FT /protein_id="CAB45292.1" FT /translation="MKNLKKAAAVTMVAGGLIAAGAGMASATDGGAHAHGKAVGSPGVA FT SGNLVQAPIHIPVNAVGNSVNVIGVLNPAFGNLGVNH" FT CDS complement(110061..110693) FT /transl_table=11 FT /gene="SCO1801" FT /gene_synonym="SCI5.09c" FT /product="putative two component response regulator" FT /note="SCI5.09c, possible two component response regulator, FT len: 210aa; similar to many eg. TR:CAB42027 (EMBL:AL049754) FT putative two component response regulator from Streptomyces FT coelicolor (228 aa) fasta scores; opt: 622, z-score: 715.0, FT E(): 1.7e-32, (48.6% identity in 214 aa overlap) and FT SW:NARL_ECOLI nitrite/nitrate response regulator from FT Escherichia coli (216 aa) fasta scores; opt: 512, z-score: FT 591.0, E(): 1.4e-25, (39.9% identity in 203 aa overlap). FT Contains Pfam matches to PF00196 Bacterial regulatory FT proteins, luxR family and PF00072 Response regulator FT receiver domain, and Prosite match to PS00622 Bacterial FT regulatory proteins, luxR family signature. Also contains FT probable helix-turn-helix 165-186aa (+3.23 SD)." FT /db_xref="GOA:Q9X9Z1" FT /db_xref="HSSP:1A04" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9X9Z1" FT /protein_id="CAB45293.1" FT /translation="MIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVDRAQE FT LKPDVILMDVKMPGMDGVDALRRLRELDNHARVLVVTSFTEQRTVVPALRAGAAGYVYK FT DVDPDALAGAIRSVHAGHILLQPEVAGALLSQEESSSGPGRAGSLTEREREVLGLIADG FT RSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVAG" FT misc_feature complement(110064..110258) FT /note="Match to PF00196 Bacterial regulatory proteins, luxR FT family Score 98.97." FT misc_feature complement(110124..110207) FT /note="PS00622 Bacterial regulatory proteins, luxR family FT signature." FT misc_feature complement(110349..110690) FT /note="Match to PF00072 Response regulator receiver domain FT Score 157.46." FT CDS complement(110695..111873) FT /transl_table=11 FT /gene="SCO1802" FT /gene_synonym="SCI33.01c" FT /gene_synonym="SCI5.10c" FT /product="putative two-component system sensor kinase" FT /note="SCI33.01c, possible two-component system sensor FT kinase (fragment), len: >383 aa; similar to N-terminal FT region of TR:Q9L1F1 (EMBL:AL157916) Streptomyces coelicolor FT putative two-component system sensor kinase SC3D11.11, 442 FT aa; fasta scores: opt: 406 z-score: 434.9 E(): 1.1e-16; FT 38.9% identity in 211 aa overlap. Contains Pfam matches to FT entries PF01590 GAF, GAF domain and PF02518 HATPase_c, GAF FT domain" FT /note="SCI5.10c, partial CDS, possible two component sensor FT kinase, len: >41aa; similar to the C-terminus of many egs. FT TR:Q52558 (EMBL:U02041) VsrA, virulence regulator from FT Ralstonia solanacearum (502 aa) fasta scores; opt: 115, FT z-score: 182.8, E(): 0.0074, (51.4% identity in 35 aa FT overlap) and SW:DEGS_BACBR DegS, sensor kinase from FT Bacillus brevis (386 aa) fasta scores; opt: 111, z-score: FT 178.6, E(): 0.013, (44.1% identity in 34 aa overlap)." FT /db_xref="GOA:Q8CK17" FT /db_xref="InterPro:IPR003018" FT /db_xref="UniProtKB/TrEMBL:Q8CK17" FT /protein_id="CAD55179.1" FT /translation="MSHGPRSGLTAVSSALLAMSRHLEVRDVLKTIVASARELLDAQYA FT ALGVPDDHGGFAQFVVDGVSDEQWKAIGPLPRQHGILAAMLHEATPERLADVRKDPRFG FT GWPSAHPDLVDFLGLPIRDGDEVLGALFLANKLRPAGGDPPHPPCPKPAGGCGFTADDE FT ELLGILAQHAAIALTNARLYERSRELTIAEERSRLAHELHDAVSQKLFSLRLTAQAATA FT LVDRDPARAKDELHQVATLAAEAADELRAAVVELRPAALEEDGLVATLRTQIQVLDRAH FT AARVTFTGHGVKALPAAQEEAMLRVAQEALHNALRHSGAERVTVTLHRRGTATVLRIAD FT NGGGFDPRTVRRAGRHLGLVSMRDRANGTGGRLTVRSAPGEGTTIEMEVPGG" FT misc_feature complement(110725..110982) FT /note="Pfam match to entry PF02518 HATPase_c, GAF domain, FT score 66.50, E-value 5.2e-17" FT misc_feature complement(111328..111804) FT /note="Pfam match to entry PF01590 GAF, GAF domain, score FT 82.20, E-value 1.1e-20" FT RBS complement(111875..111879) FT CDS 112091..112786 FT /transl_table=11 FT /gene="SCO1803" FT /gene_synonym="SCI33.02" FT /product="putative oxidoreductase" FT /note="SCI33.02, possible oxidoreductase, len: 231 aa; FT similar to TR:Q9KAS7 (EMBL:AP001514) Bacillus halodurans FT 3-oxoacyl-(acyl-carrier-protein) reductase BH2210, 244 aa; FT fasta scores: opt: 369 z-score: 399.8 E(): 1e-14; 35.3% FT identity in 235 aa overlap. Contains Pfam match to entry FT PF00106 adh_short, short chain dehydrogenase and match to FT Prosite entry PS00061 Short-chain dehydrogenases/reductases FT family signature" FT /db_xref="GOA:Q9AJX4" FT /db_xref="HSSP:1OAA" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9AJX4" FT /protein_id="CAC28543.1" FT /translation="MPVAIITGASKGLGRALAEALAARGWDLVLDARSPEVLKEAARGL FT EVYGTRVAALPGDVTDSWHRTGLVTEARRLGGVDLLVSNASALGAEPLVRLAALPLEGL FT RRALEVNVVAALGLVREALPLLRAAPAGAVLTISSDAAAEAYETWGGYGASKAALDQLA FT AVLGAEEPGLRVWAVDPGDMATDLYAAAVPDDEDPRPDPASVVPGLLRLLDERPASGRY FT GAPALLEAR" FT misc_feature 112094..112648 FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 118.60, E-value 1.2e-31" FT misc_feature 112505..112591 FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT RBS 112774..112778 FT CDS 112786..113862 FT /transl_table=11 FT /gene="SCO1804" FT /gene_synonym="SCI33.03" FT /product="putative S-adenosylmethionine:tRNA FT ribosyltransferase-isomerase" FT /note="SCI33.03, possible S-adenosylmethionine:tRNA FT ribosyltransferase-isomerase, len: 358 aa; similar to FT SW:QUEA_ECOLI (EMBL:M37702) Escherichia coli FT S-adenosylmethionine:tRNA ribosyltransferase-isomerase FT QueA, 356 aa; fasta scores: opt: 232 z-score: 260.0 E(): FT 6.3e-07; 27.6% identity in 373 aa overlap" FT /db_xref="GOA:Q9AJX3" FT /db_xref="InterPro:IPR003699" FT /db_xref="UniProtKB/TrEMBL:Q9AJX3" FT /protein_id="CAC28544.1" FT /translation="MSPLAVRVPEELSARVPAEQRGPGLDRDDVRLLVSRGTEVSHHGF FT AELPGLLRAGDLLVVNTSPTLAAAVDGRVGHARVVVHFSTRGDDDRWAVELREPDGRGA FT TRARAEAEGVEGRGCGGLAGTKVRLPGGARLVLEEPLSARGERLWWARVSGAEVPALLR FT EHGRPIRYSYTERDQPLSVYQTVFALPYADGTGSAEMPSAARPFTARLVAELVSRGVQF FT APVTLHTGVASAESHEPPYPERFAVPEASARLINAVRAGDGRVVAVGTTAVRAVESAAG FT ADGVVRARAGWTDLVVTPERGVRVVDGLLTGLHEPEASHLLMLEAVAGQAAIDRGYEAA FT VRRRYLWHEFGDVHLLLP" FT RBS 114201..114204 FT CDS 114216..114950 FT /transl_table=11 FT /gene="SCO1805" FT /gene_synonym="SCI33.04" FT /product="putative membrane protein" FT /note="SCI33.04, possible membrane protein, len: 244 aa; FT C-terminal region highly similar to TR:Q9XAS4 FT (EMBL:AL078618) Streptomyces coelicolor hypothetical 17.2 FT kDa protein SC10A7.01, 163 aa; fasta scores: opt: 620 FT z-score: 633.5 E(): 9.9e-28; 63.1% identity in 157 aa FT overlap. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="InterPro:IPR008258" FT /db_xref="UniProtKB/TrEMBL:Q9AJX2" FT /protein_id="CAC28545.1" FT /translation="MLKNILPRGRSRSLNRTQKAAIAGVGALGAAAVALTAVPASGQTT FT TTSEAAPTAKVAYSTKQIQDVHAGVTGQLAGASQKVAAIEAKKEAAAKKATAKKATAEK FT KAAAEKAAAKRAAKETTSRSAQRTEVKKAAPKSYPNNLDGWIREARSIMKKHGIPGTYE FT GIHRNIMRESSGNPKAINDWDINAINGIPSKGLLQVIPPTFAAYHVPGTSKNIYDPVAN FT IVAACNYAADKYGTMDNVDSAY" FT misc_feature 114468..114572 FT /note="high content in alanine, glutamic acid and lysine FT amino acid residues" FT CDS complement(115077..117707) FT /transl_table=11 FT /gene="SCO1806" FT /gene_synonym="SCI33.05c" FT /product="putative ABC transporter ATP-binding protein" FT /note="SCI33.05c, conserved hypothetical protein, len: 876 FT aa; similar to TR:O65934 (EMBL:Z95890) Mycobacterium FT tuberculosis hypothetical 92.2 kDa protein MTCY28.10, 865 FT aa; fasta scores: opt: 1196 z-score: 907.2 E(): 0; 37.8% FT identity in 883 aa overlap and to TR:AAK46062 FT (EMBL:AE007039) Mycobacterium tuberculosis ABC transporter, FT ATP-binding protein MT1789, 863 aa; fasta scores: opt: 1196 FT Z-score: 892.8 E(): 4.3e-42; 37.826% identity in 883 aa FT overlap. Contains 2x Pfam matches to entry PF00498 FHA, FHA FT domain (N-terminal region) and Pfam match to entry PF00005 FT ABC_tran, ABC transporter (C-terminal region) and Prosite FT matches to entries PS00017 ATP/GTP-binding site motif A FT (P-loop) and PS00211 ABC transporters family signature. FT Also contains possible hydrophobic membrane spanning FT regions at C-terminal domain" FT /db_xref="GOA:Q9AJX1" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9AJX1" FT /protein_id="CAC28546.1" FT /translation="MGHGVPELVLESNGRTWTLDPSRSYALGRDPQGELVFDDARVSWR FT HATISFNGRGWVVEDHGSTNGTFVHGQRVQQMELGAGTVLNLGNATDGPRVSLTGAQAP FT AGAPQAQPQQQPQQPQQQPYAAQGANAGWAQQAPPAQEPFQQQAPQQAPQHGQQHQAQQ FT AGWQQQQPPQQVAPQPQQAAPHFPQQQGPGGAAGAPPVHGDRSPTTFHQFSLGRVMRIG FT RALENDLVVSDLQVSRNHAEFHSTPDGRMEIRDLGSHNGTYVNGQPIAKGGTQLLGPTD FT VVGVGHSTFQIVGDRLEEFVDTGEVSFSARHLTVTVDGGKQILKDVSFGVPEKSLIAVI FT GPSGSGKSTLLKALTGYRPADQGEVLYDNRNLYKQFAELRQRIGLVPQDDILHKELTVK FT KALKYAAKLRFPADTTGAERNARIDEVLRELKLDIHKDKKVTSLSGGQRKRVSVALELL FT TKPSLIFLDEPTSGLDPGMDRDVMQLLRGLADDGRTVLVVTHSVAELATCDKLLVMAPG FT GSVAYFGPPEEALNFFGYDTWADVFSAFENYRDYDWAGRWKGSQHYQMYAADLDAVAPQ FT SVQVPPMQAMRPPKPQGWMSQFVTLVRRYTSVIASDKGFLALMVILPAVLGAVSLLIDA FT DKGLLPNPANPQTGRIIPNGTATTVLLILAVGACFAGAANSVRELIKERVIYERERATG FT LSRSAYLMSKVFVLGLITVFQGLLVGVIGFASREIPDEGLILGGATLVELSLPIMALGF FT ASMMFGLVISSLVKTAEKTMPLLVMFAIIQVVFTGCLFALNDAVGVNQFSYLMPSRWAV FT GAAGATLDFNRISPPEKGAEADPLWEHTVGAWGMDMAALIVLGVICGFFVARFLRRHEP FT EVMRK" FT misc_feature complement(116157..116708) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 201.00, E-value 1.8e-56" FT misc_feature complement(116337..116381) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(116664..116687) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(116850..117053) FT /note="Pfam match to entry PF00498 FHA, FHA domain, score FT 71.50, E-value 1.8e-17" FT misc_feature complement(117095..117428) FT /note="high content in alanine, glutamine and proline amino FT acid residues" FT misc_feature complement(117444..117635) FT /note="Pfam match to entry PF00498 FHA, FHA domain, score FT 66.00, E-value 7.8e-16" FT CDS 117894..119948 FT /transl_table=11 FT /gene="SCO1807" FT /gene_synonym="SCI28.01" FT /product="putative integral membrane protein" FT /note="SCI28.01, possible integral membrane protein, len: FT 684 aa; similar to TR:Q9X7S6 (EMBL:AL049863) Streptomyces FT coelicolor putative membrane protein SC5H1.18, 400 aa; FT fasta scores: opt: 550 Z-score: 394.9 E(): 2.3e-14; FT 36.636% identity in 434 aa overlap. Contains possible FT membrane spanning hydrophobic regions up to about 500 aa FT then a hydrophilic C-terminal tail" FT /db_xref="UniProtKB/TrEMBL:Q9S282" FT /protein_id="CAB50875.1" FT /translation="MRGNLTAQRIGGSAMSASTSVGTKGYGTGVPWGDVLLSAIASVSW FT ALIGMAGTAALGLHLLDADAAGSLGPMTAAVVALGAGGSVTPAGDVSAFGLKGAEAHTA FT IEITPLGVGLVGALFLSFFFLRSLRAAGVVVPPAELLARAGAVVALFVAMTGGLAWAGH FT DVVTIDGGSLGLDDLPGGGGRGGLEIPGLGDVGDIGGLLPDRVGDLVEARAAVGFTVDT FT APTLLGGLVWSAGVLLIALLASRRTPLPRGCEAVHRVVRPAVSALVTVALTAVAAGLAA FT AAYAAIGDDHPRRIAGAALLGAPNGVWLGVPIGLFVPWDGRATGQPAGLLPAPLDDLLG FT SGAERPVTLERLAELDGRVWLLGVAAALMMLLAGVLTAVRTPVASGAARPLAFAGRCAL FT RLGIATAVALPLSARLTEVSVDASLSVLGVDAFGAGIDLHGHLGAALLLGAVWGTGAGA FT AGALLACASGAAGARATDLALGAGAVREGVGAGGGAYAGGGASAGPAPGPYRPGTPHRP FT PDPGANPYLRSWEGAARPESGTAPGTGGPEDARPAGAAPRDAWSLPGPGHTASGAQPPG FT STGQGQADPARQGGADPARQGDGGGSRRSGGPGRYGDGAGREDGGRDGRSDDDVYGAPT FT VAGPLGPPPGTPRRPPGPGERPPRPRPWGEGPPPPPPPPPAPPRRPRDG" FT CDS 120060..121292 FT /transl_table=11 FT /gene="SCO1808" FT /gene_synonym="SCI28.02" FT /product="putative phosphoserine phosphatase" FT /note="SCI28.02, possible phosphoserine phosphatase, len: FT 410 aa; similar to many e.g. SW:SERB_ECOLI phosphoserine FT phosphatase from Escherichia coli (322 aa) fasta scores; FT opt: 621, z-score: 674.7, E(): 3e-30, (49.8% identity in FT 219 aa overlap). Also similar to TR:O53289 (EMBL:AL021287) FT hypothetical protein from Mycobacterium tuberculosis (409 FT aa) fasta scores; opt: 1209, z-score: 1304.1, E(): 0, FT (51.8% identity in 400 aa overlap)." FT /db_xref="GOA:Q9S281" FT /db_xref="HSSP:1NNL" FT /db_xref="InterPro:IPR004469" FT /db_xref="UniProtKB/TrEMBL:Q9S281" FT /protein_id="CAB50876.1" FT /translation="MSASQTSDVPTLLVKIFGKDRPGITAGLFDTLAAYSVDVVDIEQV FT VTRGRIVLCALVTEPPRGLEGDLRATVHSWAESLKLQAEIISGIGDNRPRGFGRSLVTV FT LGHPLTAEATAAIAARITESGSNIDRIFRLAKYPVTAVEFAVSGVETEPLRTALATEAA FT ALGVDIAVVAAGLHRRAQRLVVMDVDSTLIQDEVIELFAAHAGCEDEVAEVTAAAMRGE FT LDFEQSLHARVALLAGLDASVVDKVRAEVRLTPGARTLIRTLKRLGYQVGVVSGGFTQV FT TDALQEQLGLDFAQANTLEIVDGRLTGRVTGEIVDRAGKARLLRRFAAAAGVPLSQTVA FT IGDGANDLDMLNAAGLGVAFNAKPVVREAAHTAVNVPFLDTVLYLLGITREEVEAADTL FT ADDLGDGPGRP" FT CDS complement(121364..121882) FT /transl_table=11 FT /gene="SCO1809" FT /gene_synonym="SCI28.03c" FT /product="conserved hypothetical protein" FT /note="SCI28.03c, unknown, len: 172aa; similar to FT SW:Y086_MYCTU hypothetical protein from Mycobacterium FT tuberculosis (158 aa) fasta scores; opt: 385, z-score: FT 471.9, E(): 5.9e-19, (43.5% identity in 161 aa overlap)." FT /db_xref="InterPro:IPR013078" FT /db_xref="UniProtKB/TrEMBL:Q9S280" FT /protein_id="CAB50877.1" FT /translation="MSVAEPRRIVLFRHAKADWPQVTDHERPLADRGRMDAAEAGRRLA FT DTGVPIDQALCSTSARTRETWKLAVQEFPHRPKTVYEERIYDASPGELIAVLNETPDDL FT RNVLVIGHNPGMEALTEILAGSAEDEVRERINRRGFPTAAFAVLTFTGSWKDVEPGRAA FT LVDYWAPTD" FT CDS complement(121975..122181) FT /transl_table=11 FT /gene="SCO1810" FT /gene_synonym="SCI28.04c" FT /product="putative membrane protein" FT /note="SCI28.04c, putative membrane protein, len: 68 aa. FT Contains possible hydrophobic membrane spanning regions " FT /db_xref="UniProtKB/TrEMBL:Q9S279" FT /protein_id="CAB50878.1" FT /translation="MSAPTHTRPPRATRGGVDARLPWWALALPVLAFVALLLLILNPAD FT ARAAAEQPATAHLLERLEQLTVR" FT CDS complement(122365..122481) FT /transl_table=11 FT /gene="SCO1811" FT /gene_synonym="SCI28.05c" FT /product="putative membrane protein" FT /note="SCI28.05c, putative membrane protein, len: 38 aa. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9S278" FT /protein_id="CAB50879.1" FT /translation="MPVLDPNPQHGQKKMLIVFGAFLAIFVIIGIIATIASP" FT CDS complement(122566..123831) FT /transl_table=11 FT /gene="SCO1812" FT /gene_synonym="SCI28.06c" FT /product="putative integral membrane transporter" FT /note="SCI28.06c, possible integral membrane transporter, FT len: 421aa; similar to SW:CYNX_ECOLI cyanate transport FT protein from Escherichia coli (384 aa) fasta scores; opt: FT 328, z-score: 364.0, E(): 6.1e-13, (28.0% identity in 386 FT aa overlap). Also similar to TR:O68332 (EMBL:AF033674) FT hypothetical protein from Pseudomonas marginalis pv. FT alfalfae (420 aa) fasta scores; opt: 521, z-score: 574.2, FT E(): 1.2e-24, (37.7% identity in 385 aa overlap). Contains FT possible membrane spanning hydrophobic regions." FT /db_xref="GOA:Q9S277" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9S277" FT /protein_id="CAB50880.1" FT /translation="MSEVPGEASATRAWTTWTTRLLILGIVLAAVNLRPAITSLGALLE FT EVRDGLGMSGSIAGLLTSVPPLCFAVFGVTAPRLARRFGPGAVVCAGMVAITAGLLIRP FT YAGGTGGFLAATALALMGIAVSNVLMPVIVKRYFPDRVGSMTGLYSMALAFGTSVAAAA FT TVPLTDALGGHWQPGLAVWAVLPALAVLPWIPFVRNRKAPASTAPYAPRPEDGRSAEKR FT AEQPPLRITRSRTAWALAVFFGLQATAAYITMGWMAQIFRDSGVSAGTAGLLLAVIMVM FT GVPLAFVIPRVASRLPHQGPIVVVLGVCGLAGYAGLYFAPVGGAWAWALLLGVSNCAFP FT LALTMVGMRARTGAGVAQLSAFAQSTGYLISIPGPLLVGVLYQHSGGWGLPIALMSALM FT VPQIVVGVLAGRDRTVEDEAGR" FT CDS 124007..124699 FT /transl_table=11 FT /gene="SCO1813" FT /gene_synonym="SCI28.07" FT /product="putative gntR-family transcriptional regulator" FT /note="SCI28.07, possible gntR-family transcriptional FT regulator, len: 230aa; similar to many eg. TR:O33960 FT (EMBL:U78309) pyruvate dehydrogenase complex repressor from FT Rhodobacter capsulatus (257 aa) fasta scores; opt: 326, FT z-score: 383.3, E(): 5.2e-14, (34.2% identity in 228 aa FT overlap). Also similar to TR:O68331 (EMBL:AF033674) FT hypothetical protein from Pseudomonas marginalis pv. FT alfalfae (217 aa) fasta scores; opt: 407, z-score: 476.9, FT E(): 3.1e-19, (40.4% identity in 166 aa overlap). Contains FT Pfam match to entry PF00392 gntR, Bacterial regulatory FT proteins, gntR family." FT /db_xref="GOA:Q9S276" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9S276" FT /protein_id="CAB50881.1" FT /translation="MPLSHPRRSALSEQVIAALRQQIASGEWPVGSRIPTEPELVEQLG FT VARNTVREAVRALAHNGLLDIRQGSGTYVVATSELAGVMQRRFADADPRDIAELRSTLE FT SAAARLAAERRTEKDLKQIDGLLLRREEAWESGDAEAFVSADATFHLAVVAASHNNVMT FT AMYADLGEVMRDWLRGDVGEGMSPAMHMDHARLVDAIRAGDAATAAEEAAAYPFVCRPA FT LFTPPADH" FT misc_feature 124049..124228 FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 88.10, E-value FT 1.1e-25." FT CDS complement(124788..125555) FT /transl_table=11 FT /gene="SCO1814" FT /gene_synonym="SCI28.08c" FT /gene_synonym="inhA" FT /product="putative enoyl-(acyl-carrier-protein) reductase" FT /note="SCI28.08c, inhA, probable FT enoyl-(acyl-carrier-protein) reductase, len: 269 aa; FT similar to many e.g. SW:INHA_MYCSM FT enoyl-(acyl-carrier-protein) reductase involved from FT Mycobacterium smegmatis (269 aa) fasta scores; opt: 740, FT z-score: 852.1, E(): 0, (51.3% identity in 263 aa overlap). FT Contains Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase." FT /db_xref="GOA:Q9S275" FT /db_xref="HSSP:1ENY" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9S275" FT /protein_id="CAB50882.1" FT /translation="MSGILEGKRVLITGVLMESSIAFHAAKLAQEQGAEIILTAFPRPT FT LTERIAKKLPKPTKVIELDVTNDEHLARLADVVGEELGGLDGVVHSIGFAPQDALGGNF FT LNTPFESVATAMHVSAYSLKSLTMACMPLMQNGGSVVGLTFDAQYAWPQYDWMGPAKAA FT LEATSRYMARDLGKQNIRCNLVSAGPIGSMAAKSIPGFSDLAAVWDSRSPLEWDLKDPE FT PAGRGIVALLSDWFPKTTGEIIHVDGGLHAIGA" FT misc_feature complement(124977..125534) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 20.80, E-value 5.7e-07." FT CDS complement(125561..126265) FT /transl_table=11 FT /gene="SCO1815" FT /gene_synonym="SCI28.09c" FT /gene_synonym="fabG" FT /product="probable 3-oxacyl-(acyl-carrier-protein) FT reductase" FT /note="SCI28.09c, fabG, probable FT 3-oxacyl-(acyl-carrier-protein) reductase, len: 234 aa; FT similar to many e.g. SW:FABG_MYCTU FT 3-oxacyl-(acyl-carrier-protein) reductase from FT Mycobacterium tuberculosis (247 aa) fasta scores; opt: 906, FT z-score: 997.3, E(): 0, (57.3% identity in 234 aa overlap). FT Contains Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus and to entry FT PF00106 adh_short, short chain dehydrogenase and Prosite FT match to PS00061 Short-chain dehydrogenases/reductases FT family signature." FT /db_xref="GOA:Q9S274" FT /db_xref="InterPro:IPR016040" FT /db_xref="PDB:2NM0" FT /db_xref="UniProtKB/TrEMBL:Q9S274" FT /protein_id="CAB50883.1" FT /translation="MSRSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGEPPEGFLAV FT KCDITDTEQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTF FT RVVKRANRAMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNI FT TFNVVAPGFVDTDMTKVLTDEQRANIVSQVPLGRYARPEEIAATVRFLASDDASYITGA FT VIPVDGGLGMGH" FT misc_feature complement(125588..125680) FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 59.10, FT E-value 9.5e-14." FT misc_feature complement(125738..126259) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 226.90, E-value 3e-64." FT misc_feature complement(125801..125887) FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature." FT CDS 126543..128066 FT /transl_table=11 FT /gene="SCO1816" FT /gene_synonym="SCI8.01" FT /gene_synonym="SCI28.10" FT /product="hypothetical protein" FT /note="SCI8.01, unknown, partial CDS, len: > 104 aa. FT Similar to many proteins of undefined function e.g. FT Mycobacterium tuberculosis TR:P71897 (EMBL; Z79702) FT hypothetical 54.6 KD protein (505 aa), fasta scores opt: FT 596 z-score: 748.3 E(): 0 79.6% identity in 103 aa overlap. FT Overlaps and extends into CDS SCI28.10 on the adjoining FT cosmid" FT /note="SCI28.10, partial CDS, unknown, len: >435aa; similar FT to many of undefined function egs. TR:P71897 (EMBL:Z79702) FT hypothetical protein from Mycobacterium tuberculosis (505 FT aa) fasta scores; opt: 1767, z-score: 2036.8, E(): 0, FT (63.3% identity in 431 aa overlap) and SW:TLDD_ECOLI TldD FT protein from Escherichia coli (481 aa) fasta scores; opt: FT 327, z-score: 379.0, E(): 8.9e-14, (28.0% identity in 415 FT aa overlap)." FT /db_xref="InterPro:IPR002510" FT /db_xref="UniProtKB/TrEMBL:Q8CK16" FT /protein_id="CAD55180.1" FT /translation="MPHSIDQAFTALPLRALADAALARARALGAEHADFRLERVRNASW FT RLRDARPAGSSDTTDLGYAVRVVHGGTWGFASGVDLTLDAAAKVASQAVAMAKLSAQVI FT KAAGSDERVELAAEPVHADKSWISAYEIDPFSVPDADKAALLADWSARLLAADGVDHVD FT ASLLTVHENKFYADTAGTVTTQQRVRLHPVLTAVSVDDSSGEFDSMRTLAPPAGRGWEY FT LTGTGWDWDSELAEIPELLAEKMRAPSVEAGLYDLVVDPSNLWLTIHESIGHATELDRA FT LGYEAAYAGTSFATFDQLGKLRYGSELMNVTGDRTAEHGLATVGYDDEGVEGQSWDLVK FT DGTLVGYQLDRRIARLTGFERSNGCAYADSPAHVPVQRMANVSLLPDPGGLSTEDLIGG FT VDRGIYVVGDRSWSIDMQRYNFQFTGQRFFRIENGRLAGQLRDVAYQATTTDFWGSMAA FT VGGPQTYVLGGAFNCGKAQPGQVAAVSHGCPSALFKGVNILNTTQEAGR" FT RBS 128050..128055 FT CDS 128063..129457 FT /transl_table=11 FT /gene="SCO1817" FT /gene_synonym="SCI8.02" FT /product="conserved hypothetical protein SCI8.02" FT /note="SCI8.02, unknown, len: 464 aa. Similar to many FT proteins of undefined function e.g. Mycobacterium FT tuberculosis TR: P71898 (EMBL; Z79702) hypothetical 48.7 FT KD protein MTCY3G12.20 (457 aa), fasta scores opt: 1485 FT z-score: 1670.5 E():0 53.5% identity in 454 aa overlap. FT Contains a Pfam match to entry PF01523 PmbA_TldD, Putative FT modulator of DNA gyrase." FT /db_xref="InterPro:IPR002510" FT /db_xref="UniProtKB/TrEMBL:Q9RJ51" FT /protein_id="CAB59433.1" FT /translation="MSVRSSKPHEVVERALELSRADGCVVIADEESTANLRWAGNTLTT FT NGVTRGRTLTVVATVDGREGTASGVVSRSAVTLDELEPLVRAAEAAARNAGPAEDAQPL FT VTGGAAAPDFTDAPAETSSAVFADFAPALGEAFARARAGDRELYGFANHEMTSTYVGTS FT TGLRLRHDQPNGTLELNAKSPDRTRSAWAGRATRDFKDVDPAALDAELAVRLGWAERRV FT ELPAGRYETLLPPTAVADLLIYQYWSASGRDAVEGRTVFSKPGGTRVGERLGTLPLTLR FT SDPHEPGLESAPFVVAHSSGGDQSVFDNGLPVAATDWIRDGELHRLTTTRHSAGLTGLP FT VAPAIGNLVLDGGDPDRSLDEMVAGTERGLLLTCLWYIREVDPATLLLTGLTRDGVYLV FT EHGEVVGEVNNFRFNESPVGLLGRASEAGRTEKTLPREWGDWFTRTAMPALRVPDFNMS FT SVSQGV" FT misc_feature 128126..129043 FT /note="Pfam match to entry PF01523 PmbA_TldD, Putative FT modulator of DNA gyrase, score -50.00, E-value 0.0044" FT RBS 129486..129491 FT CDS 129503..130771 FT /transl_table=11 FT /gene="SCO1818" FT /gene_synonym="tyrS" FT /product="tyrosyl-tRNA synthetase (EC 6.1.1.1)" FT /note="SCI8.03, tyrS, tyrosyl-tRNA synthetase (EC FT 6.1.1.1), len: 422 aa. Highly similar to many tyrosyl-tRNA FT synthetases e.g. Escherichia coli SW:SYY_ECOLI (EMBL: FT J01719) (423 aa), fasta scores opt: 1317 z-score: 1463.3 FT E():0 48.6% identity in 416 aa overlap and Mycobacterium FT tuberculosis SW:SYY_MYCTU (EMBL: Z98268) (424 aa), fasta FT scores opt: 1657 z-score: 1839.8 E():0 60.7% identity in FT 422 aa overlap. Contains a Prosite hit to PS00178 FT Aminoacyl-transfer RNA synthetases class-I signature and a FT Pfam match to entry PF00579 tRNA-synt_1b, tRNA synthetases FT class I (W and Y)." FT /db_xref="GOA:Q9RJ50" FT /db_xref="HSSP:2TS1" FT /db_xref="InterPro:IPR002307" FT /db_xref="UniProtKB/Swiss-Prot:Q9RJ50" FT /protein_id="CAB59434.1" FT /translation="MTDIVDELKWRGLFAQSTDEDALRKALADGPVTFYCGFDPTAPSL FT HVGHLVQVLTVRRLQQAGHRPLALVGGATGQIGDPRPTAERTLNSPETVAGWVERLRGQ FT IEPFLSFEGENAAVMVNNLDWTEGLSAIEFLRDIGKHFRVNKMLTKDSVARRLESSEGI FT SYTEFSYQLLQAMDFLQLYRRYGCTMQQGGSDQWGNLTAGLDLLHRLEPDASVHAYATP FT LMTKADGTKFGKTEGGAVWLDPEMTTPYAFYQFWLNVDDRDISTYMRILSFRSRAELEE FT LERQTEERPQARAAQRALAEELTTLVHGAGQTAAVIAASKALFGQGELAELDEATLAAA FT LSELPHVRVAEPAPVVDLFAEVGLVASKSAARRTVKEGGAYVNNAKVTGEDAVPAKEDL FT LHGRWLVLRRGKKNLAAVEITGA" FT misc_feature 129602..130288 FT /note="Pfam match to entry PF00579 tRNA-synt_1b, tRNA FT synthetases class I (W and Y), score 293.00, E-value FT 3.7e-84" FT misc_feature 129620..129652 FT /note="PS00178 Aminoacyl-transfer RNA synthetases class-I FT signature" FT CDS complement(130862..131143) FT /transl_table=11 FT /gene="SCO1819" FT /gene_synonym="SCI8.04c" FT /product="putative integral membrane protein" FT /note="SCI8.04c, possible integral membrane protein, len: FT 93 aa. Similar to Streptomyces coelicolor TR:CAB42957 FT (EMBL: AL049863) possible membrane protein SC5H1.32 (89 FT aa), fasta scores opt: 180 z-score: 240.4 E(): 5.1e-06 FT 34.2% identity in 76 aa overlap and Escherichia coli FT SW:TAG1_ECOLI (EMBL: U85771) transglycosylase associated FT protein (84 aa), fasta scores opt: 166 z-score: 223.5 E(): FT 4.4e-05 36.4% identity in 77 aa overlap. Contains a FT possible membrane spanning hydrophobic domains." FT /db_xref="GOA:Q9RJ49" FT /db_xref="InterPro:IPR007341" FT /db_xref="UniProtKB/TrEMBL:Q9RJ49" FT /protein_id="CAB59435.1" FT /translation="MGWLWAIIVGFVLGLIAKAIIPGKQHMPLWLTTICGMIGAIIGNA FT IARAAGVEATAGIDWWRHLFQLVAAIIVVGLGDAAYASVRGNRRRERA" FT RBS complement(131149..131154) FT CDS 131325..131804 FT /transl_table=11 FT /gene="SCO1820" FT /gene_synonym="SCI8.05" FT /product="putative integral membrane protein" FT /note="SCI8.05, possible integral membrane protein, len: FT 159 aa. Contains possible membrane spanning hydrophobic FT domains." FT /db_xref="UniProtKB/TrEMBL:Q9RJ48" FT /protein_id="CAB59436.1" FT /translation="MSGTGVPERSRTRAGRGESDAGGWWKQMRKQSAGGSAEVFRITGA FT RTGLQEDVRGRQRRYIISMSIRTASVILAVCLWNVERHVAIVALVLGAALPYIAVVIAN FT AGRENAPSLPSTFVTAPTPPMIMPPRAGNGAAESVPEGATADPGAGAAGEPHGRP" FT CDS complement(132270..133295) FT /transl_table=11 FT /gene="SCO1821" FT /gene_synonym="moaA" FT /product="molybdenum cofactor biosynthesis protein A" FT /note="SCI8.06c, moaA, molybdenum cofactor biosynthesis FT protein A, len: 341 aa. Highly similar to many molybdenum FT cofactor biosynthesis protein A's e.g. Mycobacterium FT tuberculosis TR:O53881 (EMBL:AL022004) MoaA-2 (360 aa), FT fasta scores opt: 1336 z-score: 1559.3 E(): 0 61.7% FT identity in 332 aa overlap and Staphylococcus carnosus FT TR:Q9ZIM6 (EMBL: AF022796) MoaA (340 aa), fasta scores opt: FT 627 z-score: 735.1 E():0 33.3% identity in 321 aa overlap. FT Contains Pfam match to entry PF01444 MoaA_NifB_PqqE, moaA / FT nifB / pqqE family and a Prosite hit to PS01305 moaA / nifB FT / pqqE family signature." FT /db_xref="GOA:Q9RJ47" FT /db_xref="InterPro:IPR007197" FT /db_xref="UniProtKB/Swiss-Prot:Q9RJ47" FT /protein_id="CAB59437.1" FT /translation="MLRRSASREGAHVLIDTYGRVATDLRVSLTDRCNLRCTYCMPEEG FT LQWLAKPDLLTDDEIVRLIDIAVTSLGIEEVRFTGGEPLLRPGLVGIVERVAALEPRPQ FT MSLTTNGIGLRRTATALKAAGLDRVNVSLDTLRPDVFKTLTRRDRHKDVLEGLAAAREA FT GLTPVKVNSVLMPGLNDDEAPDLLAWAVEHDYELRFIEQMPLDAQHGWKREGMVTAGDI FT LTSLRTRFELTAEGSEERGSAPAERWLVDGGPHRVGVIASVTRPFCSACDRTRLTADGQ FT VRTCLFATEETDLRAALRSDAPDEEIARIWRLAMWGKKAGAGLDDPTFVQPDRPMSAIG FT G" FT misc_feature complement(132450..133103) FT /note="Pfam match to entry PF01444 MoaA_NifB_PqqE, moaA / FT nifB / pqqE family, score 220.90, E-value 1.9e-62" FT misc_feature complement(133176..133211) FT /note="PS01305 moaA / nifB / pqqE family signature" FT RBS complement(133302..133306) FT CDS complement(133428..135062) FT /transl_table=11 FT /gene="SCO1822" FT /gene_synonym="SCI8.07c" FT /product="putative transmembrane transport protein" FT /note="SCI8.07c, possible transmembrane transport protein, FT len: 544 aa. A member of the sodium:solute symporter family FT it is similar to many including: Streptomyces coelicolor FT TR:O70003 (EMBL: AL022374) putative transmembrane transport FT SC5B8.17 (530 aa), fasta scores opt: 2215 z-score: 2454.2 FT E(): 0 64.5% identity in 527 aa overlap and Pseudomonas FT putida TR:O50471 (EMBL: Z71176) phenylacetic acid permease FT (520 aa), fasta scores opt: 1004 z-score: 1114.3 E():0 FT 46.3% identity in 527 aa overlap. Contains a Pfam match to FT entry PF00474 SSF, Sodium:solute symporter family and FT multiple possible membrane spanning hydrophobic domains." FT /db_xref="GOA:Q9RJ46" FT /db_xref="InterPro:IPR019900" FT /db_xref="UniProtKB/TrEMBL:Q9RJ46" FT /protein_id="CAB59438.1" FT /translation="MSPAQSVFAAELAANEASEHRPLIITLFAVFVLATLGITVWAGRQ FT TKDAADFYAGGRQFSAFQNGLAVSGDYMSAASFLGIAGAIALFGYDGFLYSIGFLVAWL FT VALLLVAEPLRNSGRYTMGDVLAYRMRQRPVRTAAGTSTIVVSIFYLLAQMAGAGILVS FT LLLGITSDAGKILIVALVGVLMIVYVTIGGMKGTTWVQMVKAVLLIGGTILITFLVLLK FT FDFNISDLLGKAAENSGAGSAFLEPGLQYGASGTTKLDFISLGIALVLGTAGLPHILIR FT FYTVPNAKAARKSVNWAIGIIGAFYLMTIALGFGAAALVGKDEIIASNPSGNTAAPLLA FT LHVGGVDSTWGAILLATISAVAFATILAVVAGLTLASSSSFAHDIYANVIRKGQATEKE FT EMRAARWATVFIGIVSIALGALARDLNVAGLVALAFAVAASANLPTILYSLFWKRFTTQ FT GALWSIYGGLIVAVGLVLFSPVVSGDPKAMFPDVDFAWFPLKNPGIISIPFGFLMGWLG FT TVLSKEEPDKAKYAELEVRSLTGTGAH" FT misc_feature complement(133662..134909) FT /note="Pfam match to entry PF00474 SSF, Sodium:solute FT symporter family, score 388.20, E-value 8.1e-113" FT CDS complement(135059..135433) FT /transl_table=11 FT /gene="SCO1823" FT /gene_synonym="SCI8.08c" FT /product="putative integral membrane protein" FT /note="SCI8.08c, possible integral membrane protein, len: FT 124 aa. Similar to the C-terminus of Streptomyces FT coelicolor TR:O70002 (EMBL: AL022374) hypothetical 20.6 KD FT protein SC5B8.16 (192 aa), fasta scores opt: 268 z-score: FT 343.6 E(): 9.1e-12 36.9% identity in 111 aa overlap. FT Contains possible membrane spanning hydrophobic domains." FT /db_xref="InterPro:IPR007436" FT /db_xref="UniProtKB/TrEMBL:Q9RJ45" FT /protein_id="CAB59439.1" FT /translation="MATDAPPPSKEEPPSQEEHRLPSAEEFSEVQQSAEFAELRRSFRS FT FAFPLTVAFVAWYLLYVLLSNYAGGFMGTKLFGNINVAFVFGIAQFVTTFLIAWWYSRH FT AAAKLDPKAEAIKTRMEGGA" FT RBS complement(135070..135074) FT RBS complement(135439..135443) FT CDS 135787..137325 FT /transl_table=11 FT /gene="SCO1824" FT /gene_synonym="ssp" FT /product="secreted subtilisin-like protease" FT /note="SCI8.09, ssp, secreted subtilisin-like protease, FT len: 512 aa. Almost identical to the Streptomyces lividans FT TR:Q54400 (EMBL: L41655) subtilisin-like protease precursor FT (512 aa), fasta scores opt: 3375 z-score: 3428.7 E(): 0 FT 99.6% identity in 512 aa overlap. Contains a Pfam match to FT entry PF00082 Peptidase_S8, Subtilase family and Prosite FT hits to PS00137 Serine proteases, subtilase family, FT histidine active site, PS00138 Serine proteases, subtilase FT family, serine active site and PS00136 Serine proteases, FT subtilase family, aspartic acid active site. Also contains FT a possible N-terminal signal sequence." FT /db_xref="GOA:Q9RJ44" FT /db_xref="HSSP:1MPT" FT /db_xref="InterPro:IPR000209" FT /db_xref="UniProtKB/TrEMBL:Q9RJ44" FT /protein_id="CAB59440.1" FT /translation="MTAPLSRHRRALAIPAGLAVAASLAFLPGTPAAATPAAEAAPSTA FT ADATSLSYVVNVASGHRPSATVRRAIAKAGGTIVTSYDRIGVIVVHSANPDFAKTVRKV FT RGVQSAGATRTAPLPSAATTDTGAPQVLGGEDLAAAKAASAKAEGQDPLESLQWDLPAI FT KADKAHEKSLGSKKVTVAVIDTGVDDTHPDIAPNFDRQASVNCVAGKPDTADRAWRPSA FT AESPHGTHVAGEIAAAKNGVGMTGVAPGVKVAGIKVSNPDGFFYTEAVVCGFMWAAEHG FT VDVTNNSYYTDPWYFNCKDDPDQKALVEAVSRASRYAEKKGAVNVAAAGNENYDLTSDE FT ITDPSSPNDTTPGDRTVDPSKCLDIPTQLPGVVTVAATGAKGLKSSFSNHGLGVIDIAA FT PGGDSTAYQTPEPPATSGLILGTLPGGKWGYMAGTSMASPHVAGVAALIKSTHPHASPA FT MVKALLYAEADATACTKPYDIDGDGKVDAVCEGPKNRNGFYGWGMADALDAVTW" FT misc_feature 136231..137178 FT /note="Pfam match to entry PF00082 Peptidase_S8, Subtilase FT family, score 178.90, E-value 8.5e-50" FT misc_feature 136324..136359 FT /note="PS00136 Serine proteases, subtilase family, aspartic FT acid active site" FT misc_feature 136465..136497 FT /note="PS00137 Serine proteases, subtilase family, FT histidine active site" FT misc_feature 137083..137115 FT /note="PS00138 Serine proteases, subtilase family, serine FT active site" FT CDS 137341..137979 FT /transl_table=11 FT /gene="SCO1825" FT /gene_synonym="SCI8.10" FT /product="putative membrane protein." FT /note="SCI8.10, possible membrane protein, len: 212 aa. FT Contains a possible membrane spanning hydrophobic domain." FT /db_xref="UniProtKB/TrEMBL:Q9RJ43" FT /protein_id="CAB59441.1" FT /translation="MREAGAAVRFPSGPPPPSSYDSIFAMDTYEDPATWGPEPVRPRWS FT LALKFVATLLFFPLLCAFWLAVAAVLFVVGLFADGIAAVSEGFGRGYMRFVDDVLGGTA FT RLGSWCVTWPELRHEGDTAHYRARVDKVVGNWTERASAPREPKKARPPVECEIPRRVYR FT GVGGRYVAEVALAQGWELRPTDVRKEVRLWWSAASHPQDASVADTAREA" FT CDS 138030..139037 FT /transl_table=11 FT /gene="SCO1826" FT /gene_synonym="SCI8.11" FT /product="putative membrane protein." FT /note="SCI8.11, possible membrane protein, len: 335 aa. FT Contains multiple possible membrane spanning hydrophobic FT domains." FT /db_xref="GOA:Q9RJ42" FT /db_xref="InterPro:IPR008457" FT /db_xref="UniProtKB/TrEMBL:Q9RJ42" FT /protein_id="CAB59442.1" FT /translation="MTPIRPPSRTTDTGRHSRPSGTGRTVVVLVLVALGALIPVLGPSP FT ALHGTGEAEAPGTGGIALLRAVLFAALSVPLGELFANRLARSLPGAPPDRPRSWSPYAA FT AVGLAAALGLASVVATGNLVPDSVADIDVGGLYASRDGRLALLEVNGFLAAGLCATSRR FT PGLQVWPLAAVIVADALRAHPTTEYSPLLGSGLTLVHLTCASLWVGGLLYVLRTLRHWG FT ATEAGPALLGLYARVAAVLLAALTATGVCSSLRRMPAGTILDQLTDTAYGRVLLAKVLL FT VAAVAALALWARIRLSRAADPLTACSPARAEVVALGVVVAVSGLLTALPVPIRW" FT CDS 139189..140175 FT /transl_table=11 FT /gene="SCO1827" FT /gene_synonym="SCI8.12" FT /product="putative DNA polymerase III, epsilon chain (EC FT 2.7.7.7)." FT /note="SCI8.12, possible DNA polymerase III, epsilon chain FT (EC 2.7.7.7), len: 328 aa. Similar to many including: FT Mycobacterium tuberculosis TR:O69678 (EMBL: AL022121) FT hypothetical 35.8 KD protein (329 aa), fasta scores opt: FT 509 z-score: 584.3 E(): 3.6e-25 41.6% identity in 315 aa FT overlap and Escherichia coli SW: DP3E_ECOLI (EMBL: X04027) FT DNA polymerase III, epsilon chain (EC 2.7.7.7) (243 aa), FT fasta scores opt: 251 z-score: 293.6 E(): 5.5e-09 27.9% FT identity in 204 aa overlap. Contains a Pfam match to entry FT PF00929 Exonuclease, Exonuclease." FT /db_xref="GOA:Q9RJ41" FT /db_xref="HSSP:1J54" FT /db_xref="InterPro:IPR006054" FT /db_xref="UniProtKB/TrEMBL:Q9RJ41" FT /protein_id="CAB59443.1" FT /translation="MLEDRTTAAPSATAWPAAYPQGYAVVDVETTGLARDDRIISAAVY FT RLDARGEVEDHWYTLVNPQRDPGPVWIHGLTSDVLRDAPLFPDVAEEFAARLDGRVLVA FT HNAVFDWQMIAREYARAEREAPVRQRLCTIALSKALDLPLPNHKLESLAAHFGVVQQRA FT HHALDDARVLAEAFRPSLLAAAAGDVRLPLHECRPLTEWSDRPAPRIGQQAGYGSYRPT FT SWRPSRKRPACPHPNPGRYEEGKRLKQGMRVAFSGDTSVERDLLEDRAVEAGLHVATSL FT SRLTSLLVTNDPDSGTSKVVKARQFGTPVVDEAAFGQLLADVEPADG" FT misc_feature 139252..139764 FT /note="Pfam match to entry PF00929 Exonuclease, FT Exonuclease, score 83.10, E-value 5.8e-21" FT CDS 140239..140472 FT /transl_table=11 FT /gene="SCO1828" FT /gene_synonym="SCI8.13" FT /product="hypothetical protein SCI8.13" FT /note="SCI8.13, unknown, len: 77 aa." FT /db_xref="UniProtKB/TrEMBL:Q9RJ40" FT /protein_id="CAB59444.1" FT /translation="MATCEVCGNNYGMTFEVHAQGAVHVFDCFSCAIHRMAPICEHCRV FT QIIGQGVEVDGHWFCGAHCARAEGRAGIVDKV" FT CDS 140536..141408 FT /transl_table=11 FT /gene="SCO1829" FT /gene_synonym="SCI8.14" FT /product="putative membrane protein" FT /note="SCI8.14, possible membrane protein, len: 290 aa. FT Weakly similar to several proteins of undefined function FT e.g. Streptomyces coelicolor TR:CAB45478 (EMBL: AL079348) FT hypothetical 30.3 KD protein SC66T3.22 (278 aa), fasta FT scores opt: 394 z-score: 463.3 E(): 1.9e-18 33.8% identity FT in 272 aa overlap and Mycobacterium leprae TR:O69480 (EMBL: FT AL023635) hypothetical 30.0 KD protein (270 aa), fasta FT scores opt: 392 z-score: 461.2 E(): 2.5e-18 30.7% identity FT in 270 aa overlap. Note it is possible that codon 28 may be FT the true translational start site. Contains a possible FT membrane spanning hydrophobic domain" FT /db_xref="InterPro:IPR002994" FT /db_xref="UniProtKB/TrEMBL:Q9RJ39" FT /protein_id="CAB59445.1" FT /translation="MLPADAGLWPSRGPPREGRSGPRYRRCVYRFLLSRQWVILTLLAV FT LLIPTMIKLGFWQMHRYEERTARNDLVAHALEAPPVPVESLTAPGEKITTRERYRTVTA FT KGRFDTDREVVVRRRTDGDDNIGYHVLTPFVLNDGKVLLVNRGWIPADGPSQTAFPKVP FT APPRGELTLTGRLMPDETTEASGIKDLEGLPDRQIMLINSEQQAERLDARVLGGYVVLK FT TPEPKNDTPEPIGGPGNENAALNFAYAIQWWLFAAAVPVGWWFLVRREKRDREAAEDVE FT PAEAEPVTV" FT RBS 141463..141467 FT CDS 141474..143261 FT /transl_table=11 FT /gene="SCO1830" FT /gene_synonym="SCI8.15" FT /product="conserved hypothetical protein SCI8.15" FT /note="SCI8.15, unknown, len: 595 aa. Similar to several FT proteins of unknown function from Streptomyces coelicolor, FT including TR:CAB52841 (EMBL: AL109848) hypothetical 68.4 KD FT protein SCI51.17 (612 aa), fasta scores pt: 2473 z-score: FT 2932.7 E(): 0 60.7% identity in 596 aa overlap and FT TR:CAB42080 (EMBL: AL049763) conserved hypothetical protein FT SCE36.11C (612 aa) fasta scores opt: 1389 z-score: 1396.7 FT E():0 45.8% identity in 605 aa overlap. As well as FT Mycobacterium tuberculosis TR:P71741 (EMBL; Z81368) FT hypothetical 72.7 KD protein (642 aa), fasta scores opt: FT 1152 z-score: 1364.6 E(): 0 39.9% identity in 622 aa FT overlap." FT /db_xref="GOA:Q9RJ38" FT /db_xref="InterPro:IPR011613" FT /db_xref="UniProtKB/TrEMBL:Q9RJ38" FT /protein_id="CAB59446.1" FT /translation="MHPHIEDYALIGDQQTAALVSADGSVDWLCLPRFDSAACFAKLLG FT DEDNGHWRIAPEGAERCTRRAYRRDTLVLDTEWETEDGAVRVTDLMPQRDRAPDLVRIV FT EGLSGEVTVRSVLRLRFDHGSIVPWVRRSDGHRVAVAGPDSAWLRSEPEVHSWGQDFGT FT HAEFTVAAGEKVAFVLTWHPSHEPRPPLIDPYMSLEHSVEDWREWAARCRYDGPHRDAV FT VRSLITLKALTYQPTGGIVAAPTTSLPEEPGGVRNWDYRFCWLRDSTLTLGALLSAGYL FT EEAEAWRDWLLRAVAGNPADLQIMYGVAGERRLPEYELPWLSGFAGSAPVRIGNDAVNQ FT LQLDVYGEVMDSLSLARLAGMRPRPQMWELQCALMEFLATAWREPDEGLWEVRGGRRQF FT VHSKVMTWVALDRAVRTLEDRPELGGGDLDGWRALRDEVHREVCEKGYDPVRNTFTQYY FT GSRELDASVLLIPRVGFLPPDDPRVVGTVDAIGAELARDGLVRRYSTEGDPVDGLPGGE FT GTFLVCSFWYADALHATGRTKEARELFERLVGLANDVGLLAEEYDPVAGHQLGNFPQAF FT SHVGLVNTALALFGGEEAG" FT RBS 143248..143253 FT CDS 143267..144022 FT /transl_table=11 FT /gene="SCO1831" FT /gene_synonym="SCI8.16" FT /product="putative oxidoreductase" FT /note="SCI8.16, possible oxidoreductase, len: 251 aa. FT Similar to several including Streptomyces coelicolor FT TR:CAB52925 (EMBL: AL109949) putative oxidoreductase FT SCJ11.40 (250 aa), fasta scores opt: 462 z-score: 489.9 FT E(): 6.4e-20 33.9% identity in 248 aa overlap and Bacillus FT megaterium SW:DHG2_BACME (EMBL: D90044) glucose FT 1-dehydrogenase II (EC 1.1.1.47) (GLCDH-II) (261 aa), fasta FT scores opt: 412 z-score: 437.9 E(): 5e-17 34.6% identity FT in 254 aa overlap. Contains Pfam matches to entry PF00106 FT adh_short, short chain dehydrogenase and PF00678 FT adh_short_C2, Short chain dehydrogenase/reductase FT C-terminus." FT /db_xref="GOA:Q9RJ37" FT /db_xref="HSSP:1FJH" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RJ37" FT /protein_id="CAB59447.1" FT /translation="MDLGLKDRVYVVTGATRGLGNAAARELVADGAKVVVTGRDEKSVA FT QAAAALGPDAVGVAADNADPEAAGRLIATARERFGRFDGVLISVGGPPPGFVADTTDEQ FT WQSAFESVFLGAVRLARAAAAELADGGVIGFVLSGSVHEPIPGLTISNGLRPGLAGFAK FT SLADELGPRGIRVVGLLPGRVDTDRVRELDGLSADPEATRAAAESRIPLRRYGAPEEFG FT RASAFLLSPAASYITGVMLPVDGGVRHGF" FT misc_feature 143288..143827 FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 113.60, E-value 3.8e-30" FT misc_feature 143903..143995 FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 41.90, FT E-value 1.4e-08" FT CDS complement(144057..144644) FT /transl_table=11 FT /gene="SCO1832" FT /gene_synonym="SCI8.17c" FT /product="putative membrane protein" FT /note="SCI8.17c, possible membrane protein, len: 192 aa. FT Contains a possible N-terminal signal sequence and a FT possible membrane spanning hydrophobic domain." FT /db_xref="UniProtKB/TrEMBL:Q9RJ36" FT /protein_id="CAB59448.1" FT /translation="MSAVLRTVNRVLTALAGLVLLALGGAVLAVGFDAPAPSWWVHQGP FT HDVLLSNAERTRWREAGWWWPVVIAGLAVLLLLALWWLVAVVRRRRLTEVLVDTGDGEG FT ATLRGRALEDVVAGEADRVDGVERAGVRLTGRRDAPEARVRLLLAPHVDPGTALHDLTT FT RALSHARDSANLASLPAEVQLRGVKHGAERVN" FT CDS complement(144641..145162) FT /transl_table=11 FT /gene="SCO1833" FT /gene_synonym="SCI8.18c" FT /product="putative membrane protein" FT /note="SCI8.18c, possible membrane protein, len: 226 aa. FT Contains a possible N-terminal signal sequence and a FT possible membrane spanning hydrophobic domain." FT /db_xref="UniProtKB/TrEMBL:Q9RJ35" FT /protein_id="CAB59449.1" FT /translation="MRRVPAGLVALLLLLLAGAFLYDVAAVRAGRSALGWRRDLARQLA FT ERPVDDTWVLVGAGVAAALGLWLLVLALTPGLRRVLPMRRTHPDVRAGLHRDAAATVLR FT DRAMEVSGVQSARVRMRRRRARVRALSHFRELDDVRADLDGVLDDAVRGLGLARPPAVS FT LRVARPGRKG" FT RBS complement(144646..144649) FT CDS complement(145318..145701) FT /transl_table=11 FT /gene="SCO1834" FT /gene_synonym="SCI8.19c" FT /product="hypothetical protein SCI8.19c" FT /note="SCI8.19c, unknown, len: ,124 aa." FT /db_xref="UniProtKB/TrEMBL:Q9RJ34" FT /protein_id="CAB59450.1" FT /translation="MTGVSDGAGELLEPLARVAPGERGATRIADRVVAKVAARAAREAL FT GPLHPDAARPYATVDVHHDTAHVRVHLELDYPCDIGARCGQVRHQVVQRVRALVGMAVP FT EVAVRVERLHLAAQYGARHGRTR" FT CDS complement(145698..145883) FT /transl_table=11 FT /gene="SCO1835" FT /gene_synonym="SCI8.20c" FT /product="putative membrane protein" FT /note="SCI8.20c, possible membrane protein, len: 61 aa. FT Contains possible membrane spanning hydrophobic domains." FT /db_xref="UniProtKB/TrEMBL:Q9RJ33" FT /protein_id="CAB59451.1" FT /translation="MSMAVVGMIAGMALGFAGYFGGFGAFLLVAALGAVGFVVGRFLEG FT DMELGDFFRTRDDRRR" FT RBS complement(145894..145897) FT CDS complement(145946..146428) FT /transl_table=11 FT /gene="SCO1836" FT /gene_synonym="SCI8.21c." FT /product="putative stress-like protein" FT /note="SCI8.21c, possible stress-like protein, len: 160 aa. FT Similar to several stress proteins e.g. Staphylococcus FT aureus TR:Q53485 (EMBL: S76213) alkaline shock protein 23 FT (169 aa), fasta scores opt: 303 z-score: 340.6 E(): FT 1.3e-11 39.3% identity in 150 aa overlap and Enterococcus FT faecalis TR:O32593 (EMBL: AJ000042) Gls24 general stress FT protein (180 aa), fasta scores opt: 218 z-score: 249.4 FT E(): 1.6e-06 31.7% identity in 126 aa overlap." FT /db_xref="InterPro:IPR005531" FT /db_xref="UniProtKB/TrEMBL:Q9RJ32" FT /protein_id="CAB59452.1" FT /translation="MSDMESNRSGQDTIETSGTAKGQTIRRGGGDPGTRGRTTIADGVV FT EKITGMAARDVSGVHAMGSGMSRTFGAVRDRVPGGTKSGVTRGVKAEVGEKQTALDLEI FT VVEYGVSIADVARDVRENVVAAVERMTGLEVVEVNIAVSDVKLPDEEDEEPEPRIR" FT CDS 146516..147304 FT /transl_table=11 FT /gene="SCO1837" FT /gene_synonym="SCI8.22" FT /product="hypothetical protein SCI8.22" FT /note="SCI8.22, unknown, len: 262 aa." FT /db_xref="UniProtKB/TrEMBL:Q9RJ31" FT /protein_id="CAB59453.1" FT /translation="MTTADRWTRAVREQLGLGRLLPLGGPGDGAWIAERAAREVLLAAA FT RGVAGVRPGDLRVGLADPDDVREPAVPLPPGALPPGPLRVTADFAVVVGPTTAVAEPLP FT ATAARLRAALAEAAAARLGLTAADVDLRVTGLLDETPEAGPEAGPGPGPVDAADTDTDT FT GDGGSDDGSEASGDEGRVARAALTVPGVARLTGVLGRPVHLTEPPPREGALPRRHVRVE FT LAVRADHRAVEVARRVRAAVSEAVADRPTVAVVVTRTDVG" FT CDS complement(147325..148128) FT /transl_table=11 FT /gene="SCO1838" FT /gene_synonym="SCI8.23c" FT /product="putative enoyl-CoA hydratase/isomerase" FT /note="SCI8.23c, possible enoyl-CoA hydratase/isomerase, FT len: 267 aa. Similar to many including: Mycobacterium FT tuberculosis TR:P75019 (EMBL: Z80343) hypothetical 29.1 KD FT protein (274 aa), fasta scores opt: 331 z-score: 381.9 E(): FT 6.7e-14 33.9% identity in 236 aa overlap and Pseudomonas FT fluorescens TR:O69762 (EMBL: Y13067) P-hydroxycinnamoyl CoA FT hydratase/lyase (276 aa), fasta scores opt: 278 z-score: FT 322.1 E(): 1.4e-10 29.7% identity in 212 aa overlap. FT Contains a Pfam match to entry PF00378 ECH, Enoyl-CoA FT hydratase/isomerase family and a Prosite hit to PS00166 FT Enoyl-CoA hydratase/isomerase signature." FT /db_xref="GOA:Q9RJ30" FT /db_xref="InterPro:IPR018376" FT /db_xref="UniProtKB/TrEMBL:Q9RJ30" FT /protein_id="CAB59454.1" FT /translation="MASPAHDPGPALDQDGVRLTVDDAIATVTLTNPAKRNAQSPALWR FT ALAEAGRRLPGSVRAVVLRAEGKSFSAGLDRQAFTPEGFDGEPSFIDLARGADAELDAT FT IAEYQEAFTWWRRSDLVSVAAVQGHAIGAGFQLALACDLRVVADDVQFAMRETSLGLVP FT DLTGTHPLVSLVGYARALEICATGRFVAAEEAVSTGLANLAVPADQLDPAVHDLVSAIL FT AAPRDAVVETKALLQGAQTRDYEAQRTAERAAQGRRLRDLAGLGE" FT misc_feature complement(147511..148053) FT /note="Pfam match to entry PF00378 ECH, Enoyl-CoA FT hydratase/isomerase family, score 110.60, E-value 3e-29" FT misc_feature complement(147700..147762) FT /note="PS00166 Enoyl-CoA hydratase/isomerase signature" FT RBS complement(148135..148139) FT CDS complement(148286..148507) FT /transl_table=11 FT /gene="SCO1839" FT /gene_synonym="SCI8.24c" FT /product="putative transcriptional regulator" FT /note="SCI8.24c, possible transcriptional regulator, len: FT 73 aa. Contains a possible helix-turn-helix motif between FT residues 32..53 (+3.35 SD)." FT /db_xref="UniProtKB/TrEMBL:Q9RJ29" FT /protein_id="CAB59455.1" FT /translation="MAETLKKGSRVTGAARDKLAADLKKKYDAGASIRALAEETGRSYG FT FVHRMLSESGVTLRGRGGATRGKKATSA" FT RBS complement(148513..148517) FT CDS complement(148844..150442) FT /transl_table=11 FT /gene="SCO1840" FT /gene_synonym="SCI8.25c" FT /product="putative ABC transporter ATP binding protein." FT /note="SCI8.25c, probable ABC transporter, ATP binding FT subunit, len: 532 aa. Highly similar to many e.g. FT Mycobacterium tuberculosis TR:O53164 (EMBL: AL021184) ABC FT transporter ATP binding protein (542 aa), fasta scores opt: FT 2213 z-score: 2308.8 E():0 63.5% identity in 542 aa overlap FT and Escherichia coli SW: YBIT_ECOLI (EMBL: AE000184) ABC FT transporter ATP-binding protein (530 aa), fasta scores FT opt: 921 z-score: 963.6 E():0 33.5% identity in 534 aa FT overlap. Contains 2xPfam match to entry PF00005 ABC_tran FT ABC transporter. In addition to Prosite hits to 2xPS00017 FT ATP/GTP-binding site motif A (P-loop) and 2xPS00211 ABC FT transporters family signature. Also contains a probable FT coiled-coil from 250 to 286 (37 residues)." FT /db_xref="GOA:Q9RJ28" FT /db_xref="HSSP:1US8" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9RJ28" FT /protein_id="CAB59456.1" FT /translation="MISASGIELRAGARVLIESATFRVAKGDRIGLVGRNGAGKTTLTK FT VLAGEGQPAAGAVTRSGEVGYLPQDPRTGDLDVLARDRILSARGLDTLIRKMRDNEQRI FT ANGQGATREKALKQYERQETEFLTKGGYAAEAEAATIAAALNLPDRVLGQPLHTLSGGQ FT RRRIELARILFSDADTLLLDEPTNHLDADSIIWLRDYLKTYRGGFIVISHDVDLVETVV FT NKVFYLDANRSQIDVYNMGWRLYQQQREADEKRRKRERQNAEKKASALHSQADKMRAKA FT TKTVAAQNMARRADKLLAGLEAERKSDKVAKLRFPEPAPCGRTPLTAEGLSKSYGSLEI FT FTDVDLAIDKGSRVVILGLNGAGKTTLLRLLGGVEKPDTGEVIEGHGLKLGYYAQEHET FT LDPERTVLENMRSANPDLDLVDVRKTLGSFLFSGDDVDKPAGVLSGGEKTRLALATLVV FT SSANVLLLDEPTNNLDPASREEILGALRTYKGAVVLVTHDEGAVEALQPERIILLPDGV FT EDLWGADYADLVALA" FT misc_feature complement(148895..149392) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 146.80, E-value 3.9e-40" FT misc_feature complement(149072..149116) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(149348..149371) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(149750..150364) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 164.70, E-value 1.5e-45" FT misc_feature complement(149924..149968) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(150320..150343) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS complement(150450..150454) FT RBS 150512..150516 FT CDS 150518..151102 FT /transl_table=11 FT /gene="SCO1841" FT /gene_synonym="SCI8.26" FT /product="conserved hypothetical protein SCI8.26" FT /note="SCI8.26, unknown, len: 194 aa. Weakly similar to a FT protein of unknown function from Mycobacterium FT tuberculosis: SW:YZ15_MYCTU (EMBL: Z73101) hypothetical FT 16.1 KD protein precursor (152 aa), fasta scores opt: 220 FT z-score: 256.4 E(): 6.5e-07 33.6% identity in 131 aa FT overlap." FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/TrEMBL:Q9RJ27" FT /protein_id="CAB59457.1" FT /translation="MAMRASLTGRCNRFSQPGVGRALSVAGARLGERVQSGLRAMDPTS FT QDGPPVHKEVIGMTGNAGNSPSICPTLRYADAKAAIRQLTEAFGFTELAVYEGEDGSVA FT HAELAQGNGAVMLGSKGSGSRFDEAMKGGGPTGVYVVVADVDAHHRRAVEHGAEILMPP FT TDQDYGSRDYMARDLEGNVWSFGTYAPEVRG" FT CDS complement(151135..152478) FT /transl_table=11 FT /gene="SCO1842" FT /gene_synonym="SCI8.27c" FT /product="conserved hypothetical protein SCI8.27c" FT /note="SCI8.27c, unknown, len: 447 aa. Similar to another FT Streptomyces coelicolor protein of unknown function: FT TR:CAB46408 (EMBL: AL096743) hypothetical 49.9 KD protein FT (475 aa), fasta scores opt: 380 z-score: 402.6 E(): FT 4.8e-15 32.1% identity in 492 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9RJ26" FT /protein_id="CAB59458.1" FT /translation="MNQRRPRRPAPRPPEGTPARSELAGMARSGLADAARVARWADSAL FT GPGRGSATADGKATLSDATAAHAARELGLPVAKVRADWDTARLAGLVEVHGGTARPGWR FT LRAWNRDDSAVLRGWVALFDAWSLAHPEPAGHEPGAVAEVVSAMPQVLSFLQLSAGPVP FT VAQLLDLLEQRVTELRTERCEVPYGPRLEPGTPGAEPDPAPATDTALAPLLDWALHALA FT AVGALTCGDGQATLTPLGSWAVWVKLEQICVAAQSPAGNIEQSAEGMLRGCGRLRPNAA FT RAEYRAWLAARPVGSAVAELLGAARGEDALLRGLAFEALRVVGAPAEPDVRGVLDEPTL FT RPYALLWLAEHDGADPEDAHEVLTRPEATWLWVDTAAAVADHGEAPLLVRHLESAVQAT FT VPALLDEVRAVGHPRTVQVLVALAAAHPDPALAKAVRRAAFQVHTGGS" FT CDS complement(152803..153930) FT /transl_table=11 FT /gene="SCO1843" FT /gene_synonym="SCI8.28c" FT /product="putative secreted protein" FT /note="SCI8.28c, possible secreted protein, len: 411 aa; FT similar to TR:Q9RRL1 (EMBL:AE002077) Deinococcus FT radiodurans hypothetical protein DR2478, 407 aa; fasta FT scores: opt: 516 Z-score: 552.7 E(): 3.8e-23; 30.469% FT identity in 384 aa overlap. Contains a Prosite hit to FT PS00120 Lipases, serine active site. Contains a possible FT N-terminal signal sequence" FT /db_xref="UniProtKB/TrEMBL:Q9RJ25" FT /protein_id="CAB59459.1" FT /translation="MRTVTATAAAVTAALATGVASVAAGRLASDAALKAPPGRPLPTEP FT RLTVHGTAAGQITLTRHLAALRPGRYGLAGDGSHAVLGPVLDTAEHGADTVVRRLERVT FT HGTLATGDRAWFTPNLYVGNPGTALDLEYADVEVPGELGPLPAWFLPGARPTWIVAVHG FT LAATREHALNLIAPLHRRNVPVLALAYRGDVGAPPSPDGLHHFGETEWRDVDAAVRYAL FT DHGARQVVLLGWSTGATMALRTAALSGVRERIAGLVLDSPVLSWETTLRALAAARRTPG FT ALLPLAVRAAQGRAGLHADRDTGTAGLHRPAVPTLIFHGPGDEVAPWRLSRRLADTHPR FT LVALHTVRDAPHGAMWNADPADYEETLRRFMTPLV" FT misc_feature complement(153217..153246) FT /note="PS00120 Lipases, serine active site" FT repeat_region 153687..153733 FT RBS complement(153940..153944) FT CDS complement(154045..154767) FT /transl_table=11 FT /gene="SCO1844" FT /gene_synonym="SCI8.29c" FT /product="putative aldolase" FT /note="SCI8.29c, possible aldolase, len: 240 aa. Similar to FT many aldolases e.g. Escherichia coli SW:FUCA_ECOLI (EMBL: FT M31059) L-fuculose phosphate aldolase (EC 4.1.2.17) (215 FT aa), fasta scores opt: 485 z-score: 552.3 E(): 2.1e-23 FT 42.3% identity in 194 aa overlap. Contains a Pfam match to FT entry PF00596 Aldolase_II, Class II Aldolase and Adducin FT N-terminal domain." FT /db_xref="GOA:Q9RJ24" FT /db_xref="HSSP:2FUA" FT /db_xref="InterPro:IPR001303" FT /db_xref="UniProtKB/TrEMBL:Q9RJ24" FT /protein_id="CAB59460.1" FT /translation="MTYSRAGGAEGAGEPDREAAGDPTAEPAREAAWAELVATARRTVA FT DGLVVGTSGNVSVRVGDTVLVTPSGVPYDRLTPDDATGVDLDGRQVLGTLVPTSELPMH FT LAVYRADPGARAVVHTHAVHATAVSLLVPELPPVHYMTAALGGPVRVAPYAAYGTAELA FT RGMLDALAGRTGCLLRNHGTITYGTSLDQAYDRTAQLEWMCRLWLTASSVPGHSPSLLT FT PAQLAEVTERLRGYGQRS" FT misc_feature complement(154051..154680) FT /note="Pfam match to entry PF00596 Aldolase_II, Class II FT Aldolase and Adducin N-terminal domain., score 97.30, FT E-value 3.1e-25" FT RBS complement(154776..154781) FT CDS 154993..156264 FT /transl_table=11 FT /gene="SCO1845" FT /gene_synonym="SCI8.30" FT /product="putative low-affinity phosphate transport FT protein" FT /note="SCI8.30, possible low-affinity phosphate transport FT protein, len: 423 aa. Highly similar to many possible FT transporters, including: Streptomyces halstedii SW: FT PITH_STRHA (EMBL: L05390) putative low-affinity inorganic FT phosphate transporter (fragment) (>213 aa), fasta scores FT opt: 505 z-score: 517.8 E(): 1.8e-21 45.9% identity in 194 FT aa overlap and Mycobacterium tuberculosis TR:O06411 (EMBL: FT Z95558) hypothetical 42.7 KD protein (417 aa), fasta scores FT opt: 1286 z-score: 1295.4 E():0 50.8% identity in 421 aa FT overlap. Contains a Pfam match to entry PF01384 PHO4, FT Phosphate transporter family. Also contains a possible FT N-terminal signal sequence and multiple possible membrane FT spanning hydrophobic domains." FT /db_xref="GOA:Q9RJ23" FT /db_xref="InterPro:IPR001204" FT /db_xref="UniProtKB/TrEMBL:Q9RJ23" FT /protein_id="CAB59461.1" FT /translation="MESFSLILAIVVVTALAFDFTNGFHDTANAMATTISTGALKPKVA FT VAMSAVLNLVGAFLSVEVANTISKGLVDETGIRPEVIFAALVGAILWNLLTWLVGLPSS FT SSHALMGGLIGAAVASAGIGAVNGDVLVTKVLLPAIAAPIVAGLAALLASRMTYSLGRR FT ADGRAAAKGYRAGQIASAGLVSLAHGTNDAQKTMGIITLALIAGGSLAPDSDPPVWVIL FT SAGLAIALGTYLGGWRIIRTMGKGLTDLQPQQGFAAQTSAATVILASSHLGFSLSTTHS FT VSGAVMGAGLGRKGGVVRWSTATRMFVAWGLTLPAAALVAALAEWVCRAGDWGTALVAV FT FLIASSFAIWRISRREVVDHTNVVDGGPVDTEGPGQPEPAGVVTTAMAAVSPPPTGATE FT ELAATLPAPATTPDPKAPSAATTV" FT misc_feature 155056..155955 FT /note="Pfam match to entry PF01384 PHO4, Phosphate FT transporter family, score 111.20, E-value 2e-29" FT repeat_region complement(155526..155572) FT CDS 156299..156520 FT /transl_table=11 FT /gene="SCO1846" FT /gene_synonym="SCI8.31" FT /product="putative membrane protein" FT /note="SCI8.31, possible membrane protein, len: 73 aa. FT Contains possible hydrophobic membrane spanning regions" FT /db_xref="UniProtKB/TrEMBL:Q9RJ22" FT /protein_id="CAB59462.1" FT /translation="MSIDWAALGSVFGVSLVVTVALVGLFTLGIVGLSRQERAAARGGS FT AALAVTGAYACFAACTAAVAYGIYLIVA" FT CDS 156919..157902 FT /transl_table=11 FT /gene="SCO1847" FT /gene_synonym="cobD" FT /product="cobalamin biosynthesis protein" FT /note="SCI8.32, cobD, cobalamin biosynthesis protein, len: FT 327 aa. Highly similar to many CobD family proteins FT involved in cobalamin (vitamin B12) biosynthesis e.g. FT Salmonella typhimurium SW:CBIB_SALTY (EMBL: L12006) CbiB FT protein (319 aa), fasta scores opt: 527 z-score: 566.6 FT E(): 3.5e-24 36.1% identity in 305 aa overlap and FT Mycobacterium tuberculosis SW:COBD_MYCTU (EMBL: Z70692) FT cobalamin biosynthesis protein (313 aa), fasta scores opt: FT 991 z-score: 1057.1 E():0 54.2% identity in 308 aa overlap. FT Contains a possible membrane spanning hydrophobic domain." FT /db_xref="GOA:Q9RJ21" FT /db_xref="InterPro:IPR004485" FT /db_xref="UniProtKB/TrEMBL:Q9RJ21" FT /protein_id="CAB59463.1" FT /translation="MRAGRVFAYGAAAGLLGDLLLGDPRRGHPVAAFGRAAGAVERVLW FT RDHRGWGTLHTVVCAGGAAVLGSAAAHAVRRSSAASVALTAAATWSVVGGTSLAREATA FT IGRALEAGDVEAARARLPHLCGRDPQALDADGIARAVVESVAENTSDAVVGALVWGAVA FT GVPGLLGFRAVNTLDAMVGHKSPRYRRYGWASARLDDLAGWPGARLTAVLTTVAGGAPR FT GAVRAWRADAAQHPSPNAGPVEASFAGALGVRLGGTLSYGGRVEHRPVLNGAAGRAVRA FT GSGDIDRAVRLSRRVGWLALGVCAGARLLARRAAAKNPGVTKGRTS" FT RBS 157885..157888 FT CDS 157899..159407 FT /transl_table=11 FT /gene="SCO1848" FT /gene_synonym="cobQ" FT /product="cobyric acid synthase" FT /note="SCI8.33, cobQ, cobyric acid synthase, len: 502 aa. FT Highly similar to many cobyric acid synthases e.g. FT Salmonella typhimurium SW:CBIP_SALTY (EMBL:L12006) CbiP FT (506 aa), fasta scores opt: 814 z-score: 928.5 E():0 44.2% FT identity in 511 aa overlap and Pseudomonas denitrificans FT SW:COBQ_PSEDE (EMBL:M62866) CobQ (484 aa), fasta scores FT opt: 1066 z-score: 1215.9 E(): 0 42.3% identity in 494 aa FT overlap. Contains a Pfam match to entry PF01656 CBIA, FT Cobyrinic acid A,C-diamide synthase and a possible membrane FT spanning hydrophobic domain." FT /db_xref="GOA:Q9RJ20" FT /db_xref="InterPro:IPR011698" FT /db_xref="UniProtKB/Swiss-Prot:Q9RJ20" FT /protein_id="CAB59464.1" FT /translation="MNGGLLVAGTTSDAGKSVVTAGICRWLVRQGVKVAPFKAQNMSLN FT SFVTRDGAEIGRAQAMQAQACRVEPTAHMNPVLLKPGGERSSQVVLLGRPVGEMSARGY FT HGGRQERLLGTVLDSLAELRGTYDAVICEGAGSPAEINLRRTDIVNMGIARGAGLPVLV FT VGDIDRGGVFASFFGTVALLAPEDQALVAGFLVNKFRGDVSLLEPGLDMLHGLTGRRTY FT GVLPFRHGLGIDEEDGLRVSLRGTVRESVVAPPVGEDVLRVAVCAVPLMSNFTDVDALA FT AEPGVVVRFVDRPEELADADLVIVPGTRGTVRALEWLRERGLADAIARRAAERRPVLGI FT CGGYQLLGEHIEDEVESRAGHVDGLGLLPVRVRFDREKTLTRAVGEALGEPVEGYEIHH FT GVAEVTGGAPFLDGCRVGRTWGTHWHGSLESDGFRRAFLREVAAAAGRRFVPAPDTSFA FT ALREEQLDRLGDLIEHHADTDALWRLIESGAPQGLPFIPPGAPA" FT misc_feature 157908..158606 FT /note="Pfam match to entry PF01656 CBIA, Cobyrinic acid FT a,c-diamide synthase, score 303.10, E-value 3.4e-87" FT RBS 159393..159396 FT CDS 159404..163057 FT /transl_table=11 FT /gene="SCO1849" FT /gene_synonym="cobN" FT /product="cobalamin biosynthesis protein." FT /note="SCI8.34, cobN, CobN protein, len: 1217 aa. Highly FT similar to many e.g. Mycobacterium tuberculosis TR: O53498 FT (EMBL: AL021922) CobN (1194 aa), fasta scores opt: 2277 FT z-score: 2513.8 E(): 0 62.2% identity in 1224 aa overlap FT and Pseudomonas denitrificans SW:COBN_PSEDE (EMBL: M62866) FT CobN protein (1275 aa), fasta scores opt: 2437 z-score: FT 2690.5 E(): 0 41.6% identity in 1258 aa overlap. Also FT similar to metal chelatases e.g. Heliobacillus mobilis FT TR:Q9ZGE5 (EMBL: AF080002) Mg chelatase subunit H (1292 FT aa), fasta scores opt: 1647 z-score: 1815.7 E(): 0 31.4% FT identity in 1145 aa overlap. Contains a possible membrane FT spanning hydrophobic domain." FT /db_xref="GOA:Q9RJ19" FT /db_xref="InterPro:IPR003672" FT /db_xref="UniProtKB/TrEMBL:Q9RJ19" FT /protein_id="CAB59465.1" FT /translation="MSTVLLLSTADTDLLAARASDAAYRIGNPTRVDVGEELPGLVDGA FT DLAVVRLLGGKRAWEDGLAALRSAGIPTVLLGGESVPDAELMAESSVPAGVVAEALRYL FT VEGGPDNLTQLARFLSDTVLLTGEGFDEPRKMPEYGVHGSRDAVAGRPTVGVLFYRAHQ FT LSGNTAFVDTLCDAIEARGANALPVYCGSLRGADPGLYELLGRADALVATVLAAGGTHA FT SQASAGGDEEAWDIGALADLDVPVLQGLCLTSSRAAWEASDAALSPMDAAMQVAIPEFD FT GRLVTVPFSFKEQGPDEVPVYVADPERAARVAGIAVRHAALGHKPNAGKKLALVFTAYP FT TKHSRVGNAVGLDTPASAVRVLDALRDAGYGVTDYPAEGDELIHRLIEAGGHDVEWLTE FT DQLASAPARVPLADYRAWFEQLDPELRDGMREAWGEPPGSLYVDGDDIVLASLRFGNVV FT VMIQPPRGFGENPIAIYHDPDMPPSHHYMAAYRWLEHSFGADAIVHMGKHGTMEWLPGK FT GLGLSAGCAPDAVLGDLPLIYPFIVNDPGEGTQAKRRGHATVVDHLVPPMARADTYGDL FT AKLEQLLDEYALVSDLDPTKAPAVRAQIWTLVKAAELHHDLHVDDQPDDDAFDEFVMHI FT DGYLCEIKDVQIRDGLHILGGGPVGEPRVNLVLAVLRASQVWGGQANALPGLRACLAAH FT FGLVEKELLAAPGAPVKVPAELTDLVDGPARSAADAIDLLEQLCRRFAEGMELREWDAE FT AVPGLVRDVLGAELAEAVAVLEFACAEVVPRLARTSDEIGHILRALDGGYVPAGPSGSP FT TRGLVNVLPTGRNFYSVDPKAIPSRLSWEVGQSLADSLIQRYLSDTGEYPKSVGLTVWG FT TSAMRTQGDDIAEILALLGCRPVWDDASRRVTGFEVVPVAELGRPRVDVTVRISGFFRD FT AFPHVVGLIDDAVRAVAELDEPASSNFVKAHADEDTAEHGDRRRATSRIFGSKPGAYGA FT GLLPLIDARNWRSDADLAEVYAVWGGYAYGRGLDGRAARGDMETAFRRIAVAAKNVDTR FT EHDLVDADDYFQYHGGMVAMVRHLTGDSPEAYVGDSATPDQVKTRTLGEETHRVFRARV FT VNPRWMAAMRRHGYKGAFEMAATVDYLFGYDATAGVVDDWMYERLSAEYVFSPENRDFM FT KKSNPWALRGITERLLEAADRGLWAEPDAETLERLRATYLELEGDLEGDDK" FT RBS 163039..163043 FT CDS 163054..165072 FT /transl_table=11 FT /gene="SCO1850" FT /gene_synonym="SCI8.35" FT /product="putative chelatase" FT /note="SCI8.35, possible chelatase, len: 672 aa. Highly FT similar to many magnesium chelatase family proteins e.g. FT Mycobacterium tuberculosis SW:YS50_MYCTU (EMBL: Z95207) FT hypothetical 67.0 KD protein (629 aa), fasta scores opt: FT 1941 z-score: 1746.0 E(): 0 54.7% identity in 675 aa FT overlap and Rhodobacter capsulatus SW:BCHI_RHOCA (EMBL: FT Z11165) magnesium-chelatase 38 KD subunit FT (Mg-protoporphyrin IX chelatase) (350 aa), fasta scores FT opt: 1114 z-score: 1008.8 E(): 0 52.7% identity in 332 aa FT overlap. Contains a Pfam match to entry PF01078 FT Mg_chelatase, Magnesium chelatase, subunit ChlI and a FT possible membrane spanning hydrophobic domain." FT /db_xref="GOA:Q9RJ18" FT /db_xref="HSSP:1G8P" FT /db_xref="InterPro:IPR011704" FT /db_xref="UniProtKB/TrEMBL:Q9RJ18" FT /protein_id="CAB59466.1" FT /translation="MSTPFPFTAVVGQDDLRLALLLNAVSPAVGGVLVRGEKGTAKSTA FT VRALSALMPEVDVVSGCRFSCDPDSPDPACPDGPHEPGAFASRPARMVELPVGASEDRL FT VGALDIERALAEGVKAFEPGLLADAHRGILYVDEVNLLHDHLVDLLLDAAAMGASYVER FT EGVSVRHASKFLLVGTMNPEEGELRPQLLDRFGLTVEVAASREPDQRVEVVRRRLAYDD FT DPAGFAARWADEEAAVRARIVGARELLPSVRLGDGALRQIAATCAAFEVDGMRADIVMA FT RTATALAAWAGRTEVLAEDVRQAALLALPHRRRRNPFDAPGLDEDKLDETLEEFGGQDG FT DGPDGDDDPDPGPGGGPGGQPEPDDAPQGDGDAAARPEAGEGGEPQPSGSGAGEQQPAR FT AAEPFRTKVLSVPGLGEGAAGRRSRARTEHGRTTGARRPQGALTKLHLAATVQAAAPHQ FT RARGRSGPGLVVRRDDLRQATREGREGNLVLFVVDASGSMAARQRMSAVKGAVLSLLLD FT AYQRRDKVGLVTFRGSAADVALPPTSSVDAAAVRLESLPTGGRTPLAAGLLRAHEVLRV FT ERLRDPARRPLMVVVTDGRATGGPEPVALAGRAARLFAAEGTASVVVDCESGPVRLGLA FT GQLAGELGGTAVTLDELRADSIAGLVRDVQGSSRRAA" FT misc_feature 163108..164064 FT /note="Pfam match to entry PF01078 Mg_chelatase, Magnesium FT chelatase, subunit ChlI, score 460.70, E-value 1.2e-134" FT RBS 165058..165063 FT CDS 165072..165671 FT /transl_table=11 FT /gene="SCO1851" FT /gene_synonym="cobO" FT /product="cob(I)alamin adenosyltransferase (EC 2.5.1.17)" FT /note="SCI8.36, cobO, cob(I)alamin adenosyltransferase (EC FT 2.5.1.17), len: 199 aa. Highly similar to many including: FT Pseudomonas denitrificans SW:COBO_PSEDE (EMBL: M62866) FT cob(I)alamin adenosyltransferase (EC 2.5.1.17) (corrinoid FT adenosyltransferase) (213 aa), fasta scores opt: 418 FT z-score: 517.2 E(): 1.9e-21 37.0% identity in 200 aa FT overlap and Mycobacterium tuberculosis TR:O05810 (EMBL: FT Z95207) cob(I)alamin adenosyltransferase CobA (207 aa), FT fasta scores opt: 918 z-score: 1124.4 E(): 0 64.7% FT identity in 207 aa overlap." FT /db_xref="GOA:Q9RJ17" FT /db_xref="HSSP:1G64" FT /db_xref="InterPro:IPR003724" FT /db_xref="UniProtKB/TrEMBL:Q9RJ17" FT /protein_id="CAB59467.1" FT /translation="MPQGKPSVVPDDGLTTRQRRNRPLVVVHTGIGKGKSTAAFGLALR FT AWNQGWPIGVFQFVKSAKWKVGEENALRVLGASGEGGSVDWHKMGEGWSWVQRDAQMDN FT EEKAREGWEQVKRDLAAETYKLYVLDEFAYPMHWGWVDTDEVVSVLRERPGTQHVVITG FT RNAPGALVEFADLVTDMSKVKHPMDAGQKGQRGIEW" FT CDS 165668..167128 FT /transl_table=11 FT /gene="SCO1852" FT /gene_synonym="cobB" FT /product="cobyrinic acid A,C-diamide synthase" FT /note="SCI8.37, cobB, cobyrinic acid A,C-diamide synthase, FT len: 486 aa. Highly similar to many including: Pseudomonas FT denitrificans SW:COBB_PSEDE (EMBL: M59236) cobyrinic acid FT A,C-diamide synthase (433 aa), fasta scores opt: 635 FT z-score: 610.8 E(): 1.2e-26 39.1% identity in 465 aa FT overlap and Mycobacterium tuberculosis TR: O05811 (EMBL: FT Z95207) CobB (457 aa), fasta scores opt: 752 z-score: 721.4 FT E(): 8.2e-33 53.9% identity in 486 aa overlap. Contains a FT Pfam match to entry PF01656 CBIA, Cobyrinic acid FT A,C-diamide synthase and a Prosite hit to PS00237 G-protein FT coupled receptors signature." FT /db_xref="GOA:Q9RJ16" FT /db_xref="InterPro:IPR011698" FT /db_xref="UniProtKB/Swiss-Prot:Q9RJ16" FT /protein_id="CAB59468.1" FT /translation="MTSSDSGSAVPRLVIAAPSSGSGKTTVATGLMAALTARGLAVSPH FT KVGPDYIDPGYHALATGRVGRNLDAYLCGPELVGPLFLHGARGCDIAVVEGVMGLYDGA FT AGEGELASTAQVAKLLRAPVVLVVDASSQSRSVAALVHGFVSWDPEVRIGGVILNKVAS FT DRHEALLREAVDSVGVPVLGVLRRAAPVETPSRHLGLVPVAERGSDAVDAVAAMGARVA FT DGCDLEALVGLARSTGALSCAAWDAGEALVSSPPPPLPVPSPGAAPPDPLVRPGRPRPQ FT APDGLRRRVAMASGAAFTFSYAEHTELLAAAGAEVVTFDPLRDEELPEGTQGLVIGGGF FT PEVYASELSANEGLRKSVAELAFSGAPVAAECAGLLYLCRELDGLPMCGVLDAAARMSK FT RLTLGYRDAVAVSDSALAVAGTRMRGHEFHRTVVEPGAGAAPAWGMRAPERRVEGFVER FT GVHASYLHTHWAAEPGVARRFVERCRTS" FT misc_feature 165701..166402 FT /note="Pfam match to entry PF01656 CBIA, Cobyrinic acid FT a,c-diamide synthase, score 234.60, E-value 1.4e-66" FT misc_feature 166124..166174 FT /note="PS00237 G-protein coupled receptors signature" FT CDS 167125..167856 FT /transl_table=11 FT /gene="SCO1853" FT /gene_synonym="cobI" FT /product="precorrin-2 C20-methyltransferase (EC 2.1.1.130)" FT /note="SCI8.38, cobI, precorrin-2 C20-methyltransferase (EC FT 2.1.1.130), len: 243 aa. Similar to many including: FT Pseudomonas denitrificans SW:COBI_PSEDE (EMBL: M59301) FT precorrin-2 C20-methyltransferase (EC 2.1.1.130) FT (S-adenosyl-L-methionine-precorrin-2 methyltransferase) FT (SP2MT) (244 aa), fasta scores opt: 322 z-score: 369.3 E(): FT 3.3e-13 30.0% identity in 240 aa overlap and to the FT N-terminus of the CobI/J fusion protein from Mycobacterium FT tuberculosis SW:COBI_MYCTU (EMBL: Z73966) cobalamin FT biosynthesis protein CobIJ [includes: precorrin-2 FT C20-methyltransferase (EC 2.1.1.130) FT (S-adenosyl-L-methionine- precorrin-2 methyltransferase) FT (SP2MT); precorrin-3 methylase (EC 2.1.1.-)] (508 aa), FT fasta scores opt: 305 z-score: 345.6 E(): 7e-12 33.1% FT identity in 242 aa overlap. Contains a Pfam match to entry FT PF00590 TP_methylase, Tetrapyrrole (Corrin/Porphyrin) FT Methylases." FT /db_xref="GOA:Q9RJ15" FT /db_xref="HSSP:1PJT" FT /db_xref="InterPro:IPR006364" FT /db_xref="UniProtKB/TrEMBL:Q9RJ15" FT /protein_id="CAB59469.1" FT /translation="MSSTLIGVGVGPGDPELVTVKGVNALRGADVVVVPVMDTGERGRA FT EATVLHYVGAEKIMRVVFALNERTDRARREAAWDAAGERVAGLLREHAAVAFATIGDPN FT VYSTFTYLAQTVGALVPGTVVQTVPGITAMQDLAARSGAVLTEGTEPLTLVPVTAGSAV FT LKEALHGPGTVVAYKFGRQAAEVAEALRESGRLDDAVWGSALGLPEESVRPAGELDGAP FT LPYLSTLIAPARREGGRGGKL" FT misc_feature 167134..167781 FT /note="Pfam match to entry PF00590 TP_methylase, FT Tetrapyrrole (Corrin/Porphyrin) Methylases., score 78.90, FT E-value 1.1e-19" FT CDS complement(167877..168605) FT /transl_table=11 FT /gene="SCO1854" FT /gene_synonym="SCI39.01c" FT /gene_synonym="SCI8.39" FT /product="putative permease" FT /note="SCI39.01c, possible integral membrane protein FT (fragment), len: >174 aa. Contains possible hydrophobic FT membrane spanning regions" FT /note="SCI8.39, possible permease, partial CDS, len: > 104 FT aa. Weakly similar to Escherichia coli SW:BTUC_ECOLI (EMBL: FT M14031) vitamin B12 transport system permease protein (326 FT aa), fasta scores opt: 101 z-score: 140.5 E():1.9 32.5% FT identity in 77 aa overlap. Contains possible membrane FT spanning hydrophobic domains." FT /db_xref="GOA:Q8CK15" FT /db_xref="InterPro:IPR003689" FT /db_xref="UniProtKB/TrEMBL:Q8CK15" FT /protein_id="CAD55181.1" FT /translation="MAVFVALGAFLMTLAGGWTAQRVTDRRHLVLGLAGGLMLGVVGLD FT LLPEALEAAGDEVFGVPAALLLFVAGFLLAHLVERLLAARRAAHGADEHEHRSPEVGLT FT AAAAMVGHSAMDGVAIGAAFQVGGGMGAAVAMAVIAHDFADGFNTYTLTSLYGNARRRA FT VAMLVADAIAPVLGASSTLLFTIPEGALGAYLGLFGGVLLYLAAAEILPEAHHEHPARS FT TLLCTVAGAAFIWLVVGIAE" FT CDS 168668..169513 FT /transl_table=11 FT /gene="SCO1855" FT /gene_synonym="SCI39.02" FT /product="putative precorrin-4 C11-methyltransferase" FT /note="SCI39.02, probable precorrin-4 FT C11-methyltransferase, len: 281 aa; similar to TR:O87696 FT (EMBL:AJ000758) Bacillus megaterium precorrin-4 methylase FT CbiF, 258 aa; fasta scores: opt: 674 Z-score: 771.2 bits: FT 150.4 E(): 2.3e-35; 41.502% identity in 253 aa overlap and FT to SW:COBM_PSEDE (EMBL:M59301) Pseudomonas denitrificans FT precorrin-4 C11-methyltransferase (EC 2.1.1.133) CobM, 253 FT aa; fasta scores: opt: 652 Z-score: 746.5 bits: 145.8 FT E(): 5.5e-34; 43.145% identity in 248 aa overlap . Contains FT Pfam match to entry PF00590 TP_methylase, Tetrapyrrole FT (Corrin/Porphyrin) Methylases" FT /db_xref="GOA:Q93RX1" FT /db_xref="HSSP:1CBF" FT /db_xref="InterPro:IPR006362" FT /db_xref="UniProtKB/TrEMBL:Q93RX1" FT /protein_id="CAC38790.1" FT /translation="MRRMHRRGPKTMDSEAKVTFVGAGPGAADLLTFRAARAIAEADVV FT IWAASLVQAEVLQHAREGAEVLDSATMSLEDVVAVYRRARAEGLRVARIHSGDPALWGG FT TQEQLDRCAEIGVATEVVPGVSAFSAVAALAQRELTIPEVAQSVVLTRLGGGKTPMPPG FT EEVREFAKHGTTMAVFLSAARSGQLVRELLEGGYPTETPVIVAYQATWPEELVVRCTIG FT TLEETVKEHRLWKHTLFLVGPALDAHGTRSHLYHPGHFHGYRKADPEARRELRSRGAST FT " FT misc_feature 168716..169342 FT /note="Pfam match to entry PF00590 TP_methylase, FT Tetrapyrrole (Corrin/Porphyrin) Methylases., score 180.30, FT E-value 3.1e-50" FT misc_feature 169519..170064 FT /note="Pfam match to entry PF00590 TP_methylase, FT Tetrapyrrole (Corrin/Porphyrin) Methylases., score -5.80, FT E-value 3.3e-05" FT CDS 169519..170751 FT /transl_table=11 FT /gene="SCO1856" FT /gene_synonym="SCI39.03" FT /product="putative precorrin-6Y C5,15-methyltransferase" FT /note="SCI39.03, probable precorrin-6Y FT C5,15-methyltransferase, len: 410 aa; similar to FT SW:COBL_PSEDE (EMBL:M59301) Pseudomonas denitrificans FT precorrin-6Y C5,15-methyltransferase [decarboxylating] (EC FT 2.1.1.132) CobL, 413 aa; fasta scores: opt: 614 Z-score: FT 634.0 bits: 126.3 E(): 1e-27; 37.500% identity in 408 aa FT overlap. Contains Pfam match to entry PF00590 TP_methylase, FT Tetrapyrrole (Corrin/Porphyrin) Methylases" FT /db_xref="GOA:Q93RX0" FT /db_xref="HSSP:1UFK" FT /db_xref="InterPro:IPR006365" FT /db_xref="UniProtKB/TrEMBL:Q93RX0" FT /protein_id="CAC38791.1" FT /translation="MVGMGAASGAAPAGDVAAGAELVVGGRRHLDAVRLPEGVRTVVLG FT ALAPALDTVAEYVARGRPVTVLASGDPGFFGIVRALAERFGPERLDVRAGVSSVAAAFA FT RVGLPWDDAVVASAHGRDLRTAVNVCRAHPKVAVLTGPGAGPAELGAALRDDGRVFVVA FT SALGSAEERVERVTPAEAAARDWGTAVSVVLCLDGARAPGPVRALAGVRPGPAGWALAE FT DAFTHRDSMITKFEVRALALARLGPRPGDLVWDVGAGSGSVAVECARLGAAVTAVERTP FT DGVGRVRANAAAHGVDLRVVHGAAPAVLAGLDEVPDAVFVGGGGRELPSIVAECARRAR FT RSVVVAVAALDRVPAAREALLGAGLDCDGVLLQSSRLAPLPGDVTRLAATNPVFLLWGV FT RPHGRTEGVAP" FT CDS 170829..172580 FT /transl_table=11 FT /gene="SCO1857" FT /gene_synonym="SCI39.04" FT /product="putative bifunctional protein (CbiGH)" FT /note="SCI39.04, probable bifunctional protein (CbiGH), FT len: 583 aa; N-terminal region similar to SW:CBIG_SALTY FT (EMBL:L12006) Salmonella typhimurium involved in cobalamin FT synthesis CbiG protein, 351 aa; fasta scores: opt: 312 FT Z-score: 304.6 bits: 65.6 E(): 2.2e-09; 32.986% identity in FT 288 aa overlap and C-terminal region similar to FT SW:CBIH_SALTY (EMBL:L12006) Salmonella typhimurium FT precorrin-3B C17-methyltransferase (EC 2.1.1.131) CbiH, 241 FT aa; fasta scores: opt: 684 Z-score: 658.7 bits: 130.6 E(): FT 4.3e-29; 46.862% identity in 239 aa overlap. Contains Pfam FT match to entry PF01890 CbiG, CbiG and PF00590 TP_methylase, FT Tetrapyrrole (Corrin/Porphyrin) Methylases and match to FT Prosite entry PS00639 Eukaryotic thiol (cysteine) proteases FT histidine active site" FT /db_xref="GOA:Q93RW9" FT /db_xref="InterPro:IPR006363" FT /db_xref="UniProtKB/TrEMBL:Q93RW9" FT /protein_id="CAC38792.1" FT /translation="MYDGPVGDAVRAAFAECERLVCFLATGAVVRLVAPLLDDKRTDPG FT VVCVDEGGRFAVSLVGGHGGGANELARAVGEVLGAEPVVTTATDAVGLAGLDTLGMPVE FT GDVAGVSRALLDGEPVALRAEVAWPLPPLPVAAEGAYGIRVTDRAVEPAAGEVVLRPPS FT LVVGVGASRGAPVDEVLGLVEAALREAGLSAASVAELATVDAKAGEPGIVGAAGRLGVP FT LVTHPADELAGVEVPNPSDAPLAAVGTPSVAEAAALVRGGELLVPKRKSAAVPAMATCA FT VVRRPGRGRLAVVGLGPGARDLVTPRARAELRRASVLVGLDQYVDQIRDLLRPGTRVLE FT SGLGAEEERARTAVEEARLGHAVALIGSGDAGVYAMASPALAEASDDIDVVGVPGVTAA FT LAAGAVLGAPLGHDHVSISLSDLHTPWEVIERRVRAAAEADLVVTFYNPRSRGRDWQLP FT KALAILAEHREPTTPVGVVRNASRADESSRLCTLAALDPATVDMMTVVTVGNTATREIA FT GRMVTPRGYRWQTRETAPPAERPGSSPTAEVSAEPDVPDASAEPDVPAAPDVSAARDVS FT ATPEETL" FT misc_feature 170910..171665 FT /note="Pfam match to entry PF01890 CbiG, CbiG, score FT 168.90, E-value 8.2e-47" FT misc_feature 171696..172316 FT /note="Pfam match to entry PF00590 TP_methylase, FT Tetrapyrrole (Corrin/Porphyrin) Methylases., score 113.80, FT E-value 3.3e-30" FT misc_feature 171903..171935 FT /note="PS00639 Eukaryotic thiol (cysteine) proteases FT histidine active site" FT RBS 172567..172571 FT CDS 172577..173494 FT /transl_table=11 FT /gene="SCO1858" FT /gene_synonym="SCI39.05" FT /product="conserved hypothetical protein" FT /note="SCI39.05, conserved hypothetical protein, len: 305 FT aa; similar to TR:O87690 (EMBL:AJ000758) Bacillus FT megaterium Cbi protein CbiX, 306 aa; fasta scores: opt: 791 FT Z-score: 870.2 bits: 169.1 E(): 7e-41; 39.000% identity in FT 300 aa overlap. Contains Pfam match to entry PF01903 CbiX, FT CbiX" FT /db_xref="GOA:Q93RW8" FT /db_xref="InterPro:IPR002762" FT /db_xref="UniProtKB/TrEMBL:Q93RW8" FT /protein_id="CAC38793.1" FT /translation="MTTPPALLIAGHGTRDEAGAEAFRDFVRELGRRHPELPVAGGFIE FT LSPPPLGDAVAELVERGVRRFAAVPLMLVSAGHAKGDIPAALAREKERHPGITYTYGRP FT LGPHPGLLRVLERRLAEAVDPAWDPAEVTVLLVGRGSTDPDANAEVFKAARLLWEGRGY FT AGVETAFVSLAEPDVPGGLERCVRLGARRVVVLPYFLFTGILPDRVRHQTEEWAAAHPE FT TDVRSADVIGPEPELLDLVWERYEEAVGGDLRMNCDSCVYRIALPGFEDKVGLPQQPHF FT HPDDDGDHPHGHHHGHGHAHSHAH" FT misc_feature 172604..172942 FT /note="Pfam match to entry PF01903 CbiX, CbiX, score FT -17.50, E-value 0.0059" FT CDS 173535..174554 FT /transl_table=11 FT /gene="SCO1859" FT /gene_synonym="SCI39.06" FT /product="putative aminotransferase" FT /note="SCI39.06, probable aminotransferase, len: 339 aa; FT similar to SW:HIS8_ECOLI (EMBL:X03416) Escherichia coli FT histidinol-phosphate aminotransferase (EC 2.6.1.9) HisC, FT 356 aa; fasta scores: opt: 351 Z-score: 375.7 bits: 78.0 FT E(): 2.4e-13; 29.450% identity in 309 aa overlap. Contains FT Pfam match to entry PF00222 aminotran_2, Aminotransferase FT class-II and match to Prosite entry PS00105 FT Aminotransferases class-I pyridoxal-phosphate attachment FT site" FT /db_xref="GOA:Q93RW7" FT /db_xref="HSSP:1LC8" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:Q93RW7" FT /protein_id="CAC38794.1" FT /translation="MRDDGAALVDLAVNVRAGTPPAWLREHVAASLGSLAAYPDGRAAR FT AAVAARHGLPVERVLLTAGAAEAFVLLARALKVRRPVVVHPQFTEPETALRDAGHTVGR FT VLLRAADGFRLDPAAVPEDADLVVVGNPTNPTSVLHPADVLASLARPGRTLVVDEAFMD FT AVPGEREALAGRTDVPGLVVLRSLTKTWGLAGLRIGYVLADPETVAGLERAQPLWPVST FT PALAAAEACVAPRALAEAAHAAHRVAADRDRLVAGLAVSAGAGVRVVGPAEGPFVLVGV FT PDGAAVRHRLRDLGYAVRRGDTFPGLGGGWLRLAVRDRATTEGFLNALDRALTATEPA" FT misc_feature 173691..174473 FT /note="Pfam match to entry PF00222 aminotran_2, FT Aminotransferase class-II, score 24.40, E-value 1.8e-08" FT misc_feature 174090..174131 FT /note="PS00105 Aminotransferases class-I FT pyridoxal-phosphate attachment site" FT stem_loop 174533..174603 FT /note="possible stem-loop. Score 54: 22/25 (88%) matches, 0 FT gaps" FT CDS complement(175100..176107) FT /transl_table=11 FT /gene="SCO1860" FT /gene_synonym="SCI39.07c" FT /product="putative secreted protein" FT /note="SCI39.07c, putative secreted protein, len: 335 aa. FT Contains match to Prosite entry PS00017 ATP/GTP-binding FT site motif A (P-loop) and possible N-terminal region signal FT peptide sequence and a possible hydrophobic membrane FT spanning region at the C-terminal domain" FT /db_xref="GOA:Q93RW6" FT /db_xref="InterPro:IPR019931" FT /db_xref="UniProtKB/TrEMBL:Q93RW6" FT /protein_id="CAC38795.1" FT /translation="MSLMRAPHACLTGGPTTLNGNTFRMPARRLATVAAATALAAGPAT FT LAGAGSAHATGDHGRASATVLRTGLDVSLLNKTVNVPLAVTLNEVQAPESAEKTALTAR FT LDGVDGGKPFSVLRADVAEARATATAGKSEGSTTLARARLHVPGLPLLSVIEVQEVTST FT ATCEAGKQPVADANLLGPVTVLGKKVTLTTGGTTDVKVPGVGEVRLDLSKEETTSRTAA FT ATALELKVSVNPGDLNVAEVDGTVTLARATCESPAAPADEAGQPPARADEPPAEQDAER FT PAEPAADVKAQGARTEADLAETGGSSATPYVAAGAAALVLAGGGALVLARRRRG" FT misc_feature complement(175709..175732) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(176254..177345) FT /transl_table=11 FT /gene="SCO1861" FT /gene_synonym="SCI39.08c" FT /product="conserved hypothetical protein" FT /note="SCI39.08c, conserved hypothetical protein, len: 363 FT aa; similar to SW:YT15_MYCTU (EMBL:Z74697) Mycobacterium FT tuberculosis hypothetical 39.8 kDa protein RV2915c, 370 aa; FT fasta scores: opt: 1341 Z-score: 1487.0 bits: 283.8 E(): FT 3.1e-75; 56.630% identity in 362 aa overlap" FT /db_xref="GOA:Q93RW5" FT /db_xref="InterPro:IPR006680" FT /db_xref="UniProtKB/TrEMBL:Q93RW5" FT /protein_id="CAC38796.1" FT /translation="MSDRAVLHVKGRVLVGPEEVRDEVWVIDGRISYDRPTGAADVRTV FT EGWALPGLVDAHCHVGLDQHGAVPADVAEKQALTDREAGTLLVRDAGSPSDTRWIDDRE FT DLPKIIRAGRHIARTRRYIRNYAWEVEPDDLVAYVAQEARRGDGWVKLVGDWIDRDLGD FT LSACWPRGAVEAAIAEAHRLGARVTAHCFAEDSLRDLVEAGIDCVEHATGLTDDTIPLF FT AERGVAIVPTLVNIATFPALADGGESRFPRWSAHMRRLHERRYDTVRSAYDAGIPVFVG FT TDAGGALAHGLAGAEVAELVTAGIPPVEALAATTWAARRWLGRPGLDEGAPADLVVYEQ FT DPRADVRVLTAPRRVVLNGRVVG" FT CDS complement(177401..177883) FT /transl_table=11 FT /gene="SCO1862" FT /gene_synonym="SCI39.09c" FT /product="putative integral membrane protein" FT /note="SCI39.09c, possible integral membrane protein, len: FT 160 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q93RW4" FT /protein_id="CAC38797.1" FT /translation="MFLVLLLIVVVAVVSAVGLTGHGASVLAARRARGTGAGPALRALA FT AFAGAAAVAMYAWGLLHVTGAVMESDGGAGSAPAPPCRTTGNEERALHVIDQSVSFLPL FT GFVCETTGGGEYTSDDVPGYVNPATAALALTAVAGAVGAGYASEARARATARGGGG" FT CDS complement(177995..179215) FT /transl_table=11 FT /gene="SCO1863" FT /gene_synonym="SCI39.10c" FT /product="hypothetical protein SCI39.10c" FT /note="SCI39.10c, unknown, len: 406 aa. High content in FT arginine amino acid residues and also highly hydrophilic" FT /db_xref="UniProtKB/TrEMBL:Q93RW3" FT /protein_id="CAC38798.1" FT /translation="MRVSGIPSDSSFRKAGPGRPLPRLLGGPPGGLRVGLHAPLDQRGT FT QCRQAALHGPARRVRTVVVDPDHLARQRAAARRQRQRRVGLQGTGHQRGRVDVRRRAQC FT RRHRRRVPRLVHVRLQAAQRERAGPGGRRRGRVPRHHRAGALRLDALDAGLQREHLQLR FT RRVQQRLAPAVDPALLPVEERQVRPPRGVRVRRHAGPGPLAHRHRRDARRAAHRLLRAD FT DAQVHAPGVRQHRLRAHRGHGVQVEQRAVRPDHLADLRDRVGVAGRRLGVHQGHEVDLR FT VFGQGPADLLGGDGRVERHGEVVHGRAAVPQPVAEGLPVRSRDDVQRDGAGPRGGADGA FT LQRQQRLALHDHHVLAGAEQVRDPVLDRGETSGAQRGEVQEGMGHGGALFGDGGCAARV FT RGVRSRE" FT CDS 179518..180030 FT /transl_table=11 FT /gene="SCO1864" FT /gene_synonym="SCI39.11" FT /product="putative acetyltransferase" FT /note="SCI39.11, probable acetyltransferase, len: 170 aa; FT similar to SW:ECTA_MARHA (EMBL:U66614) Marinococcus FT halophilus L-2,4-diaminobutyric acid acetyltransferase (EC FT 2.3.1.*) EctA, 172 aa; fasta scores: opt: 443 Z-score: FT 540.9 bits: 106.5 E(): 1.5e-22; 42.675% identity in 157 aa FT overlap. Contains Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family" FT /db_xref="GOA:Q93RW2" FT /db_xref="InterPro:IPR000182" FT /db_xref="UniProtKB/Swiss-Prot:Q93RW2" FT /protein_id="CAC38799.1" FT /translation="MTAAQADLQIDRPRVADGAALWRIARDSEVLDLNSSYSYLLWCRD FT FAATSAVVRDGHGVPVGFITGYVRPDSPDTLLVWQVAVDGTYRGRGLAATLVDGLADRV FT ARERGITILETTISPDNTASQRLFTSFAERRGARLEREVLFDTAVFPDGPHEPEVLYRI FT GPLSAGG" FT misc_feature 179671..179919 FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 57.60, E-value FT 2.6e-13" FT RBS 180146..180150 FT CDS 180160..181431 FT /transl_table=11 FT /gene="SCO1865" FT /gene_synonym="SCI39.12" FT /product="putative aminotransferase" FT /note="SCI39.12, probable aminotransferase, len: 423 aa; FT similar to SW:ECTB_MARHA (EMBL:U66614) Marinococcus FT halophilus diaminobutyrate--pyruvate aminotransferase (EC FT 2.6.1.46) EctB, 427 aa; fasta scores: opt: 1512 Z-score: FT 1688.4 bits: 321.4 E(): 1.9e-86; 53.333% identity in 420 FT aa overlap. Contains 2x Pfam matches to entry PF00202 FT aminotran_3, Aminotransferase class-III pyridoxal-phosphate FT and and match to Prosite entry PS00599 Aminotransferases FT class-II pyridoxal-phosphate attachment site" FT /db_xref="GOA:Q93RW1" FT /db_xref="HSSP:1QJ3" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/Swiss-Prot:Q93RW1" FT /protein_id="CAC38800.1" FT /translation="MTITQPDLSVFETVESEVRSYCRGWPTVFDRAVGSRMYDEDGHEY FT LDFFAGAGSLNYGHNNAVLKRALIDYLERDGVTHGLDMSTTAKRRFLETFQNTILRPRD FT LPYKVMFPGPTGTNAVESALKLARKVKGRESIVSFTNAFHGMSLGSLAVTGNAFKRAGA FT GIPLVHGTPMPFDNYFDGTVEDFIWFERLLEDQGSGLNKPAAVIVETVQGEGGINVARA FT EWLRALADLCERQDMLLIVDDIQMGCGRTGAFFSFEEAGITPDIVTVSKSISGYGMPMA FT LTLFKPELDVWEPGEHNGTFRGNNPAFVTATATLEAYWADGSAMEKQTRKRGEQVEQHM FT IAITEENLADVKEYRGRGLVWGLEFHDKDRAGRVAKRAFELGLLIETSGPESEVVKLLP FT ALTITPDELDEGMKTLARAVRETA" FT misc_feature 180259..181077 FT /note="Pfam match to entry PF00202 aminotran_3, FT Aminotransferase class-III pyridoxal-phosphate, score FT 235.70, E-value 2e-81" FT misc_feature 180961..180990 FT /note="PS00599 Aminotransferases class-II FT pyridoxal-phosphate attachment site" FT misc_feature 181210..181362 FT /note="Pfam match to entry PF00202 aminotran_3, FT Aminotransferase class-III pyridoxal-phosphate, score FT 28.60, E-value 2.2e-09" FT RBS 181532..181537 FT CDS 181550..181948 FT /transl_table=11 FT /gene="SCO1866" FT /gene_synonym="SCI39.13" FT /product="putative condensing enzyme" FT /note="SCI39.13, probable condensing enzyme, len: 132 aa; FT similar to SW:ECTC_MARHA (EMBL:U66614) Marinococcus FT halophilus L-ectoine synthase EctC, 129 aa; fasta scores: FT opt: 405 Z-score: 541.3 bits: 105.8 E(): 1.5e-22; 44.800% FT identity in 125 aa overlap" FT /db_xref="GOA:Q93RW0" FT /db_xref="InterPro:IPR010462" FT /db_xref="UniProtKB/Swiss-Prot:Q93RW0" FT /protein_id="CAC38801.1" FT /translation="MIVRSFKEFEGTDRHVKSASGTWESTRIVLAKEKVGFSVHETILY FT AGTETSMWYANHIEAVVCTKGDAELTDRETGKTYHITPGTMYLLDGHERHTLKVKEDFH FT CICVFNPPVTGREDHDENGVYPLLTEEV" FT CDS 182012..182854 FT /transl_table=11 FT /gene="SCO1867" FT /gene_synonym="SCI39.14" FT /product="putative hydroxylase" FT /note="SCI39.14, possible hydroxylase, len: 280 aa; similar FT to TR:O06499 (EMBL:D78338) Dactylosporangium L-proline FT 4-hydroxylase, 272 aa; fasta scores: opt: 458 Z-score: FT 529.1 bits: 105.7 E(): 7.1e-22; 34.351% identity in 262 aa FT overlap" FT /db_xref="GOA:Q93RV9" FT /db_xref="InterPro:IPR008775" FT /db_xref="UniProtKB/Swiss-Prot:Q93RV9" FT /protein_id="CAC38802.1" FT /translation="MATPRQDPVVWGSPDAPGPVSAGDLQALDRDGFLAIDQLITPDEV FT GEYQRELERLTTDPAIRADERSIVEPQSKEIRSVFEVHKISEVFAKLVRDERVVGRARQ FT ILGSDVYVHQSRINVKPGFGASGFYWHSDFETWHAEDGLPNMRTISVSIALTENYDTNG FT GLMIMPGSHKTFLGCAGATPKDNYKKSLQMQDAGTPSDEGLTKMASEYGIKLFTGKAGS FT ATWFDCNCMHGSGDNITPFPRSNVFIVFNSVENTAVEPFAAPIRRPEFIGARDFTPVK" FT CDS complement(182936..184030) FT /transl_table=11 FT /gene="SCO1868" FT /gene_synonym="SCI39.15c" FT /product="conserved hypothetical protein" FT /note="SCI39.15c, conserved hypothetical protein, len: 364 FT aa; similar to SW:YCBU_BACSU (EMBL:AB000617) Bacillus FT subtilis hypothetical protein homologue of class-V proteins FT of pyridoxal-phosphate-dependent aminotransferase YcbU, aa; FT fasta scores: opt: 277 Z-score: 303.9 bits: 64.9 E(): FT 2.5e-09; 27.707% identity in 314 aa overlap" FT /db_xref="GOA:Q93RV8" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:Q93RV8" FT /protein_id="CAC38803.1" FT /translation="MDGEVTGPHSGAMESFENLVRTEFAPKTTYLNTASTGLLPARTLA FT AMRDAAASAAEGQPLDMFADVEASRAAYARLVGVPATRVATGASVATFSGLVAASLPPG FT AEVLTAEADFSSLVNPLYTRGDLKVRSVPLERLAESVGPDTALVAVSSVQSADGRLADL FT AALRDAARAHGARTLIDASQSNGWLPLAAGDFDFVVAVAYKWVLCPRGVAFLVVPEDLG FT AAAGLTPLFAGWASGEHPWDSCYGPVEELAHSARRFDESPALFSYTGARHSLALIEELG FT VDAVHAHDTGLADRFRAGVRSLGHEPVDAPGSAIVSVPGLGHRQGELGGAGVQVSDRAG FT NLRAAFHAYNTAADVDRLLDVLAG" FT CDS complement(184090..184803) FT /transl_table=11 FT /gene="SCO1869" FT /gene_synonym="SCI39.16c" FT /product="conserved hypothetical protein" FT /note="SCI39.16c, conserved hypothetical protein, len: 237 FT aa; similar to TR:O68911 (EMBL:AF058302) Streptomyces FT roseofulvus FrnE protein, 216 aa; fasta scores: opt: 528 FT Z-score: 605.5 bits: 119.3 E(): 3.9e-26; 46.919% identity FT in 211 aa overlap and to TR:Q9ZA40 (EMBL:AJ011500) FT Streptomyces violaceoruber putative disulphide bond-forming FT protein Gra-ORF19, 220 aa; fasta scores: opt: 316 Z-score: FT 366.6 bits: 75.1 E(): 7.9e-13; 37.104% identity in 221 aa FT overlap" FT /db_xref="GOA:Q93RV7" FT /db_xref="InterPro:IPR001853" FT /db_xref="PDB:3GL5" FT /db_xref="UniProtKB/TrEMBL:Q93RV7" FT /protein_id="CAC38804.1" FT /translation="MRVEIWSDIACPWCYVGKARFEKALAAFPHRDGVEVVHRSFELDP FT GRAKDDVQPVLTMLTAKYGMSQEQAQAGEDNLGAQAAAEGLAYRTRDRDHGSTFDLHRL FT LHLAKERGRHEALLDAFYRGNFADERSVFNDDERLVELAVGAGLDAEEVRAVLADPAAY FT ADEVRADEREAAQLGATGVPFFVLDRAYGVSGAQPAEVFTQALTQAWGERTPLKLIDDG FT GAEACGPDGCAVPGH" FT CDS complement(184896..185504) FT /transl_table=11 FT /gene="SCO1870" FT /gene_synonym="SCI39.17c" FT /product="hypothetical protein SCI39.17c" FT /note="SCI39.17c, unknown, len: 202 aa" FT /db_xref="InterPro:IPR009784" FT /db_xref="UniProtKB/TrEMBL:Q93RV6" FT /protein_id="CAC38805.1" FT /translation="MTLDLPELPFPLRPYGPDGRWSYADGVLTGVAGSRQDRFVPPTGE FT SLESVSDAPRLLGAPDGDFQLIARVSVGFRGAFDAGVLYVHVGERAWAKLCLEYSPDVP FT TVCTVVTRGHSDDCNSFTVEGDSVWFRVSRTGRAFAFHASLDGERWTFVRLFTLGDEEE FT TGSALVGFLAQAPTGEGCTVTYDHLEFRPAWPADLRDGS" FT CDS complement(185648..187177) FT /transl_table=11 FT /gene="SCO1871" FT /gene_synonym="SCI39.18c" FT /product="putative aldehyde dehydrogenase" FT /note="SCI39.18c, probable aldehyde dehydrogenase, len: 509 FT aa; similar to TR:Q56694 (EMBL:U39638) Vibrio harveyi fatty FT aldehyde dehydrogenase AldH, 510 aa; fasta scores: opt: FT 1209 Z-score: 1264.1 bits: 243.5 E(): 8e-63; 42.300% FT identity in 487 aa overlap. Contains Pfam match to entry FT PF00171 aldedh, Aldehyde dehydrogenase family" FT /db_xref="GOA:Q93RV5" FT /db_xref="HSSP:1EZ0" FT /db_xref="InterPro:IPR016162" FT /db_xref="UniProtKB/TrEMBL:Q93RV5" FT /protein_id="CAC38806.1" FT /translation="MAAAPVWSVDPRTGKQREQVAVEATAQEVDAAVRAAHAARDALAD FT RAVRAAFLRSAADELKAAESTLVEVADAETALGPVRLTGELARTCYQLRAFADIVDEGE FT YLGVVVNHPDDTATPPIPDLRRYKVPLGVVAVYSASNFPFAFSVPGGDTASALAAGCPV FT VVKAHPDHPALSELVAKVLRRAAARHGIPDGVLGLVHGFEAGVELIKHPLVAAAGFTGS FT VRGGRALFDAAAARPVPIPFHGELGSLNPVVVTEAAAVERAEAIGAGLAGSMTLGVGQF FT CVKPGLVLVPAGDAGDGLVKSLTDAVSATDAGVLLDHRMRDNFVAGVAERAALPDVDSP FT VTPGSGGEHTVSAGFLTVPAARLAAEGEHDLLLEECFGPVTVVARYQDEGEVRGVLSRL FT PGNLTATVQLSAEEVAGEGAGTALLAEVTPLAGRVLVNGWPTGVAVAAAQQHGGPYPAT FT TSTSTSVGGTAIERWLRPVAYQGVPEALLPVELRDDNPLGLPRRFNGVLER" FT misc_feature complement(185735..187177) FT /note="Pfam match to entry PF00171 aldedh, Aldehyde FT dehydrogenase family, score -107.40, E-value 8.3e-10" FT RBS complement(187186..187190) FT CDS 187300..188073 FT /transl_table=11 FT /gene="SCO1872" FT /gene_synonym="SCI39.19" FT /product="putative IclR-family transcriptional regulator" FT /note="SCI39.19, probable IclR-family transcriptional FT regulator, len: 257 aa; similar to SW:ICLR_ECOLI FT (EMBL:M31761) Escherichia coli acetate operon repressor FT IclR, 274 aa; fasta scores: opt: 413 Z-score: 491.6 bits: FT 98.6 E(): 8.7e-20;31.855% identity in 248 aa overlap and to FT TR:Q9RDE7 (EMBL:AL136503) Streptomyces coelicolor putative FT IclR-family transcriptional regulator SCC77.11, 265aa; FT fasta scores: opt: 766 Z-score: 904.5 bits: 175.0 E(): FT 8.6e-43; 52.846% identity in 246 aa overlap. Contains Pfam FT match to entry PF01614 IclR, Bacterial transcriptional FT regulator and possible helix-turn-helix motif at residues FT 32..53 (+3.00 SD)" FT /db_xref="GOA:Q93RV4" FT /db_xref="InterPro:IPR005471" FT /db_xref="UniProtKB/TrEMBL:Q93RV4" FT /protein_id="CAC38807.1" FT /translation="MSAVETGGGAQVKSAVRTVELLEYFAGRPGMHSLASVQEAVGYPK FT SSLYMLLRTLVELGWVETDATGTRYGIGVRALLVGTSYIDGDEVVAAARPTLDRLSDDT FT TETIHLARLDGTNVVYLATRQSQHYLRPFTRVGRRLPAHSTSLGKALLSTYTDEQVRKM FT LPETLPALTEHTITDREKLIEELRLVREQGFAVDREENTLGLRCFGVAVPYRTPARDAI FT SCSVPVARLTPAHEQMVKDALFDARDRLTLATRRL" FT misc_feature 187507..188058 FT /note="Pfam match to entry PF01614 IclR, Bacterial FT transcriptional regulator, score 161.50, E-value 1.4e-44" FT CDS 188077..188547 FT /transl_table=11 FT /gene="SCO1873" FT /gene_synonym="SCI39.20" FT /product="putative acetyltransferase" FT /note="SCI39.20, probable acetyltransferase, len: 156 aa; FT similar to TR:Q9SKZ7 (EMBL:AC006223) Arabidopsis thaliana FT putative alanine acetyl transferase AT2G32020, 183 aa; FT fasta scores: opt: 205 Z-score: 253.5 bits: 53.3 E(): FT 1.6e-06; 31.210% identity in 157 aa overlap. Contains Pfam FT match to entry PF00583 Acetyltransf, Acetyltransferase FT (GNAT) family" FT /db_xref="GOA:Q93RV3" FT /db_xref="HSSP:1NSL" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q93RV3" FT /protein_id="CAC38808.1" FT /translation="MHIALREVHDSDLPVFFRQMNDPEALRMAAFTPKDPADWDAFTAH FT WTKIRASRDVVRTILGDGDVVGSTAVYGEPGEREVTYWVDRAYWGQGVATAALRALLAE FT VRDRPLYARAAADNTGSRRVLEKCGFVTSARARGFATARGAEIDEVVLHLAK" FT misc_feature 188245..188469 FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 48.30, E-value FT 1.7e-10" FT CDS 188656..188868 FT /transl_table=11 FT /gene="SCO1874" FT /gene_synonym="SCI39.21" FT /product="hypothetical protein" FT /note="SCI39.21, hypothetical protein, len: 70 aa; similar FT to C-terminal region of many two-component system response FT regulators, e.g. TR:Q9K3I0 (EMBL:AL390188) Streptomyces FT coelicolor putative two-component system response regulator FT 2SCG18.07, 220 aa; fasta scores: opt: 154 Z-score: 195.9 FT bits: 41.7 E(): 0.0025; 54.717% identity in 53 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q93RV2" FT /protein_id="CAC38809.1" FT /translation="MGAWTHDSDVRRHPAHRRLRPNARGEVLRPMASGLTDAKIAGRPG FT AGPAAAKMHVASVPARTGARDRTQG" FT CDS 188988..190442 FT /transl_table=11 FT /gene="SCO1875" FT /gene_synonym="SCI39.22" FT /product="putative secreted penicillin binding protein" FT /note="SCI39.22, possible secreted penicillin-binding FT protein, len: 484 aa; similar to TR:Q9L656 (EMBL:AF241575) FT Streptomyces griseus PbpA, 485 aa; fasta scores: opt: 1581 FT Z-score: 1674.1 bits: 319.2 E(): 1.2e-85; 51.633% identity FT in 490 aa overlap and to TR:Q9XA17 (EMBL:AL079308) FT Streptomyces coelicolor putative penicillin binding protein FT SCH69.17, 490 aa; fasta scores: opt: 1649 Z-score: 1745.9 FT bits: 332.5 E(): 1.2e-89; 52.965% identity in 489 aa FT overlap. Contains Pfam match to entry PF00905 FT Transpeptidase, Penicillin binding protein transpeptidase FT domain and match to Prosite entry PS00017 ATP/GTP-binding FT site motif A (P-loop). Also contains N-terminal region FT signal peptide sequence" FT /db_xref="GOA:Q93RV1" FT /db_xref="InterPro:IPR001460" FT /db_xref="UniProtKB/TrEMBL:Q93RV1" FT /protein_id="CAC38810.1" FT /translation="MNKTIRRASVLTLLLVFALLVRATWVQFYEGRALADGKDNRRNAI FT ETYAEPLGNIIVAGRSVTGSAQTEGGDLAYRRTYENGKLYAAVTGYASQAYAPTQLEGV FT YQDVLNGTDPRLRTVMDTVTGARAEPGNVVTTIDPDVQRAGFEALGDKKGAAVAIDPKT FT GRILSVVSTPSYDPASLTDANTAGAAWEKLTGDPDKPLTNRALRRPLPPGSTFKLVVAA FT AALENGLYGSVDEKTDSPDPYTLPDTTTDLTNENPNAPCENATIRTALRYSCNNVFAKM FT AVDLGQDELRAMAEKFGFNDETQDVPVRAYTSVYPKDMNRSSTALTGIGQFDVTATPLQ FT MAMVSAALANGGELVSPHMVSQVTDSGGDVLEDHTDADSKRIVSSTTAEQLQSAMRTVV FT EQGTGSNAQIPGATVGGKTGTAQHGENNSKTPYAWFTSYAKSESSDKEVAVAVVVEQSD FT AARSEVSGNGLAAPVAKAMMEAALKG" FT misc_feature 189402..190415 FT /note="Pfam match to entry PF00905 Transpeptidase, FT Penicillin binding protein transpeptidase domain, score FT 266.40, E-value 3.9e-76" FT misc_feature 190218..190241 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 190506..190510 FT CDS 190519..191091 FT /transl_table=11 FT /gene="SCO1876" FT /gene_synonym="SCI39.23" FT /product="putative RNA polymerase sigma factor" FT /note="SCI39.23, possible RNA polymerase sigma factor, len: FT 190 aa; similar to SW:RPOE_STRCO (EMBL:L29636) Streptomyces FT coelicolor RNA polymerase sigma-E factor SigE, 176 aa; FT fasta scores: opt: 210 Z-score: 262.1 bits: 55.1 E(): FT 5.2e-07; 34.177% identity in 158 aa overlap. Contains FT possible helix-turn-helix motif at residues 132..153 (+3.59 FT SD)" FT /db_xref="GOA:Q93RV0" FT /db_xref="InterPro:IPR007627" FT /db_xref="UniProtKB/TrEMBL:Q93RV0" FT /protein_id="CAC38811.1" FT /translation="MGTVVDDAAGEFRAFFERHYAELARLAHLLTGEPDAADDLAADAL FT LALWHRWDRVRAADHPVAYARGVVANLARTRVRAAVRERRRVALFWSQREERTENPDVA FT GVVDVREALRRLPFRKRACVVLRHSFDLSEKDTALALGISVGTVKSQTSKGVAELQRLL FT GTRTAPRAPGQVRAAIAHSGETAGGAR" FT RBS 191077..191081 FT CDS 191088..191762 FT /transl_table=11 FT /gene="SCO1877" FT /gene_synonym="SCI39.24" FT /product="hypothetical protein SCI39.24" FT /note="SCI39.24, unknown, len: 224 aa" FT /db_xref="UniProtKB/TrEMBL:Q93RU9" FT /protein_id="CAC38812.1" FT /translation="MTGRREPDERLRARLREAAGAHEPDRARILARIEHGMAAGDRGPS FT RPPLPGWVRVAGATAAVAGVLVAGGYAVAPVVRDDAPAQRPAATAPASREPGPLWSGGA FT VDPHSNEFWAQSNITLGTNAPLTALTVELRVAQTGSVTSTGAWRSLPEDDFAFTVGERA FT GFLVYRWTLKEGRTVPAGEWVFAGQYNHERGGRDAGGDRYSATATAASGRLTVRGGFTP FT DG" FT CDS complement(191775..192572) FT /transl_table=11 FT /gene="SCO1878" FT /gene_synonym="SCI39.25c" FT /product="putative secreted protein" FT /note="SCI39.25c, possible secreted protein, len: 265 aa. FT Contains possible N-terminal region signal peptide FT sequence" FT /db_xref="GOA:Q93RU8" FT /db_xref="InterPro:IPR014403" FT /db_xref="UniProtKB/TrEMBL:Q93RU8" FT /protein_id="CAC38813.1" FT /translation="MHKPLRIATVTATCAVAGAVLYTTGAASAGQSTANSTHEPYNIGV FT LAKDIDAYYGTTLDADGVYQASPDSPYAADLARVDAAAKKQIDRAARTAHHKHTRPAVV FT FDIDDTLLLSLDYEKKNNYGYDGATWAAYVDRADRPAVPGSPELARYADKKGVEVFYNS FT GLGEAQRAAAVENLKKAGADVNLDASHMFLKDKANPPSYLAHCATPGSWTCTTVQYKAG FT TRRHIERDLGYDVVANFGDQYSDLQGGYADRTYKLPNPTYFVE" FT CDS complement(192697..193842) FT /transl_table=11 FT /gene="SCO1879" FT /gene_synonym="SCI39.26c" FT /product="putative secreted pectinesterase" FT /note="SCI39.26c, probable secreted pectinesterase, len: FT 381 aa; similar to SW:PME_BURSO (EMBL:M62803) Burkholderia FT solanacearum pectinesterase precursor (EC 3.1.1.11) Pme, FT 396 aa; fasta scores: opt: 350 Z-score: 372.6 bits: 77.7 FT E(): 3.7e-13; 32.036% identity in 334 aa overlap. Contains FT Pfam match to entry PF01095 Pectinesterase, Pectinesterase FT and match to Prosite entry PS00503 Pectinesterase signature FT 2. Contains also possible N-terminal region signal peptide FT sequence" FT /db_xref="GOA:Q93RU7" FT /db_xref="HSSP:1QJV" FT /db_xref="InterPro:IPR018040" FT /db_xref="UniProtKB/TrEMBL:Q93RU7" FT /protein_id="CAC38814.1" FT /translation="MHPPAPSRRGFLLATAGAGAALGLAAAGPAVAGARPHPRPFGRYG FT SPAARRTPRTLYVDPHGRGDFTSVQSAVDAAAGDGWALVLAPGTYRETVSVDAQRTGAT FT WIGASGDPRDVVIVYDNAAGTPKPDGSGTHGTSGSATTTVRADGFTARAVTFANDWLRA FT DRPDWTGTQAVAIKVMGDRSAFHDCRFLGHQDTLYADSRDLALFARQYYERCYVEGDVD FT FVFGRATAVYEQCHFRTLVRTDLDAAPYGFVFAPSTAGANPRGYLVIRGRVSSEAPDGY FT YKLARPWVPSSDTTARPMLTVRETRLGAGVDAVAPYANMRDAYPWQEQRFREYRNTGPG FT AAVTVPDNRPQLTRAEAAAHTREAYLGDWRPYDRQHHHGRY" FT misc_feature complement(192739..193842) FT /note="Pfam match to entry PF01095 Pectinesterase, FT Pectinesterase, score 125.30, E-value 1.1e-33" FT misc_feature complement(193165..193194) FT /note="PS00503 Pectinesterase signature 2" FT RBS complement(193850..193855) FT CDS complement(193909..195243) FT /transl_table=11 FT /gene="SCO1880" FT /gene_synonym="SCI39.27c" FT /product="putative secreted pectate lyase" FT /note="SCI39.27c, probable secreted pectate lyase, len: 444 FT aa; similar to SW:PEL_BACS (EMBL:X74880) Bacillus subtilis FT pectate lyase precursor (EC 4.2.2.2) Pel, 420 aa; fasta FT scores: opt: 1127 Z-score: 1249.8 bits: 240.3 E(): 5e-62; FT 42.431% identity in 436 aa overlap. Contains 2x Pfam FT matches to entry PF00544 pec_lyase, Pectate lyase. Contains FT also possible N-terminal region signal peptide sequence" FT /db_xref="GOA:Q93RU6" FT /db_xref="HSSP:1JRG" FT /db_xref="InterPro:IPR012334" FT /db_xref="UniProtKB/TrEMBL:Q93RU6" FT /protein_id="CAC38815.1" FT /translation="MSTQRWHGHATKRAAALVGCTALVLSLTAATAEARPGHHHPRDTA FT RQTLPAGDGWASQGPGTTGGSAADAEHVYTVSTWAEFRAALAADGTAPRIIKVKGTVDA FT VSEGCEAFAAPGYDFDAYLEKYSPENWGMDTDLSAEPDDSPEGLRRVSAARQDRTIKAN FT VPSNTTIIGVGRGAALKGASLQIKGVDNVIVRNLTFESPVDCFPQWDPTDGDRGNWNSE FT YDSAVVYGSTHVWLDHNTFTDGEHPDSAAPTYFGMLYQQHDGQLDIVKGADYVTASWNV FT FTEHDKTILIGNSDSESTAAVDRGHLRATFHHNLFKNLVERAPRVRFGQVDVYNNHFVA FT SDDYAYSFGVGKESALVAEHNAFTLPAGVSPAKVLKRWNDSPLSAAHNRVNGRTVDLIA FT AHNAENPDAVLRSGAGWTPSLRTKVLPARAVPFVVDHGAGAGRLR" FT misc_feature complement(194143..194757) FT /note="Pfam match to entry PF00544 pec_lyase, Pectate FT lyase, score 227.40, E-value 2.1e-64" FT misc_feature complement(194929..195204) FT /note="Pfam match to entry PF00544 pec_lyase, Pectate FT lyase, score 42.70, E-value 1.3e-10" FT RBS complement(195253..195256) FT CDS complement(195308..196111) FT /transl_table=11 FT /gene="SCO1881" FT /gene_synonym="SCI39.28c" FT /product="putative secreted protein" FT /note="SCI39.28c, putative secreted protein, len: 267 aa; FT similar to TR:O31528 (EMBL:Z99107) Bacillus subtilis YesY FT protein, 217 aa; fasta scores: opt: 548 Z-score: 648.8 FT bits: 127.5 E(): 1.5e-28; 43.939% identity in 198 aa FT overlap and to TR:Q9L936 (EMBL:AF184175) Bacillus sp. FT KCCM10143 cephalosporin C deacetylase 217 aa; fasta scores: FT opt: 544 Z-score: 644.2 bits: 126.6 E(): 2.7e-28; 44.500% FT identity in 200 aa overlap. Contains possible N-terminal FT region signal peptide sequence" FT /db_xref="GOA:Q93RU5" FT /db_xref="InterPro:IPR001087" FT /db_xref="UniProtKB/TrEMBL:Q93RU5" FT /protein_id="CAC38816.1" FT /translation="MSLSRRQVAAAAVSSIPLAFATTGTAQAGGRHHPRTLYIAGDSTA FT AQKYSDAAPETGWGMALPFFLRNGLRVANHAVNGRSSRSFVDEGRLDAVLGAIRPGDFL FT LIQFAHNDEKDEDPARYTEPWTTYQDYLRRYVAGARARGARPVLATPVERRRFDAEGNA FT VPSHGEYPAAMRALARQEGVALLDVQVLSLALWQRLGAEGTKAYFNWTATEQDNTHFNP FT PGAIAVARLVARELLRGRVLAHRDVRRLEEEIPGSWISWPAPATA" FT CDS complement(196244..197602) FT /transl_table=11 FT /gene="SCO1882" FT /gene_synonym="SCI39.29c" FT /product="putative secreted sugar-binding protein" FT /note="SCI39.29c, probable secreted sugar-binding protein, FT len: 452 aa; similar to TR:P72397 (EMBL:Y07706) FT Streptomyces coelicolor putative maltose-binding protein FT MalE, 423 aa; fasta scores: opt: 433 Z-score: 459.6 bits: FT 94.2 E(): 5.2e-18; 30.716% identity in 433 aa overlap. FT Contains Pfam match to entry PF01547 SBP_bacterial_1, FT Bacterial extracellular solute-binding protein and possible FT N-terminal region signal peptide sequence" FT /db_xref="GOA:Q93RU4" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:Q93RU4" FT /protein_id="CAC38817.1" FT /translation="MLSSRDKGTVRRRTSAAVALGAVLALTATACGDDGSGAGGDKGAE FT GSGKGKITFWDNNGGIRTAVWKTIIADFEKANPDIDVEYVGIAATEYQSKVDTAIQGGG FT LPDVGGVTASMLAGFSAQGALEPLDDRLGKSPLSDKVNKDMVESLKAAGGGDGTLYSMP FT TSANNGVLYYRTDLFEKAGLDAPTTWDKFYAAAEKLTDAGKNEFGYTIRGGSGSIAQAL FT DAMYGQSGITSFWDAGKKKTTVNDPKNVEALEKYAALYKKVTPAADVNNDFAKMVAQWD FT TGTIGMLNHNLGSYQDHVKALGVDKFRGIPQPVGASGKRVQVSNPVDGLGMFKSSKNKE FT AAWKFIEFATSKEQNSKFNESAGQVPSSTEAANDAWIQKAEPTKLAAQALNDGSTTIVQ FT LPYYLPDWNTLSKSESEPGFQKVLLGDMSAKDFLDGLADKLNEAQAEWTEQMG" FT misc_feature complement(196277..197137) FT /note="Pfam match to entry PF01547 SBP_bacterial_1, FT Bacterial extracellular solute-binding protein, score FT 127.70, E-value 7.6e-35" FT RBS complement(197609..197612) FT CDS complement(197678..199222) FT /transl_table=11 FT /gene="SCO1883" FT /gene_synonym="SCI7.01c" FT /gene_synonym="SCI39.30c" FT /product="putative xylanase" FT /note="SCI7.01c, partial CDS, possible xylanase, len: FT >95aa; similar to the N-terminal region of many eg. FT TR:O30426 (EMBL:AF005383) xylanase from the thermophile FT Caldocellum saccharolyticum (1347 aa) fasta scores; opt: FT 263, z-score: 357.5, E(): 1.4e-12, (35.2% identity in 91 aa FT overlap)." FT /note="SCI39.30c, probable xylanase (fragment), len: >458 FT aa; similar to TR:Q9WXE8 (EMBL:AB022865) Prevotella FT ruminicola xylosidase, 452 aa; fasta scores: opt: 553 FT Z-score: 572.6 bits: 115.2 E(): 2.6e-24; 37.954% identity FT in 303 aa overlap" FT /db_xref="GOA:Q8CK14" FT /db_xref="InterPro:IPR013320" FT /db_xref="UniProtKB/TrEMBL:Q8CK14" FT /protein_id="CAD55182.1" FT /translation="MTAVESAGTTYTNPVLNADWSDPDVVRVGDDFYLTASSFGRVPGL FT PLLHSRDLVHWTLVGHALERLEPEREFARPRHDCGVWAPSLRHHAGRFWIFWGDPDQGV FT FQVNAPDVRGPWTAPHLVKAGKGLIDPCPLWDEETGEAFLVHAWARSRSGIKNRLTGHR FT MRPDGTGVLDEGKVIVDADRLPGWFTLEGPKLYRHDGWYWILAPAGSVETGWQGAFRSR FT EFFGPYEEKVVLEQKDTDVNGPHQGGWVRTASGEDWFLHFQQRGAYGRVVHLQPMRWSP FT DGWPALGDDGAPVAEHPRPALPPQPPAAPATDDDFPGGRFGRQWSWTANPRAGWATQHA FT GDGLRLACVRSADAHDLRLLPSVLTQRFPGEPSVIEVELRLDSEVPGARAGLAVLGDAY FT RWIGLQRDADGTVHLVHRFAESVAETERDADRPRPAPGGRVRLRIETVPGARCRFSYDL FT GDGDPGDGPCPVPVGREFAATPWRWVGALLGLFALAPAGQGPAGTATFTRFRVGPH" FT CDS complement(199219..200064) FT /transl_table=11 FT /gene="SCO1884" FT /gene_synonym="SCI7.02c" FT /product="hypothetical protein" FT /note="SCI7.02c, unknown, len: 281aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X9Y8" FT /protein_id="CAB46385.1" FT /translation="MTGNDSPVLRVAGRPVARYVTRPELPHRLSPRPYLHPVATLAGTA FT VTEFSPADHLHHLGVGVAVPDVEGHNFWGGRTYVRGRGPTELDNHGTQRHTAFQLRDPD FT GFVEELRWVAAGAELLRERRTVAAAELTGTAWALDFTFSLTNVTRDPLTLGSPATNGRP FT GAAYGGFFWRARKESTPPGVFTADREGEREVHGRGADWLALTGETWSLVFAGATERTRR FT DPWFVRTEEYPGVGSSLAHDDRVTVAPGDTLVRRIVTVVADGRLDADGAAALVRKAVSP FT " FT CDS complement(200061..201218) FT /transl_table=11 FT /gene="SCO1885" FT /gene_synonym="SCI7.03c" FT /product="putative oxidoreductase" FT /note="SCI7.03c, possible oxidoreductase, len: 385 aa; FT similar to many proteins of undefined function eg. FT TR:Q45376 (EMBL:X90711) from a locus required for FT lipopolysaccharide biosynthesis in Bordetella pertussis FT (350 aa) fasta scores; opt: 232, z-score: 266.7, E(): FT 1.6e-07, (28.0% identity in 275 aa overlap). Contains Pfam FT match to entry PF01408 GFO_IDH_MocA, Oxidoreductase FT family." FT /db_xref="GOA:Q9X9Y7" FT /db_xref="InterPro:IPR004104" FT /db_xref="UniProtKB/TrEMBL:Q9X9Y7" FT /protein_id="CAB46386.1" FT /translation="MSRVPVVLAGARGHGRWHVANIRRLERAGLVRLAGICELTPLTEQ FT EAEGELPEQSADFGALLDSTGARVAVICTPIPTHTDLALTAARRGVHLLLEKPPAPSYA FT EFRRMADGVAEAGVACQVGFQSLGSHAVPAIRELVARGAIGEVVGIGGAGAWVRDEDYF FT RRAPWSGKRRLNGADVIDGALTNPLAHAVATALALGGTARAEDVTGIETELSHANDIEA FT DDTSCVRIGTARGHRVTVAATLCAERAAEPYVLVHGSSGRVTFWYKQDRVLLQRGGHGP FT EEFHHDRTDLLENLVDHLTTGAPLLVPPDETGAFMRVVEAIRRAPDPEPLPEAAWRRLP FT GERRRVVPGIDGLVAAAADTLSLYSELGAPWAPRTEHPRHEVSTR" FT misc_feature complement(200448..201209) FT /note="Pfam match to entry PF01408 GFO_IDH_MocA, FT Oxidoreductase family, score 71.60, E-value 1.7e-17." FT CDS complement(201215..202111) FT /transl_table=11 FT /gene="SCO1886" FT /gene_synonym="SCI7.04c" FT /product="putative integral membrane transport protein" FT /note="SCI7.04c, possible integral membrane transport FT protein, len: 298aa; similar to many eg. SW:YURM_BACSU FT hypothetical ABC transporter from Bacillus subtilis (300 FT aa) fasta scores; opt: 582, z-score: 650.2, E(): 6.9e-29, FT (31.7% identity in 293 aa overlap) and TR:O87858 FT (EMBL:AL031013) putative transmembrane sugar transport FT protein from Streptomyces coelicolor (279 aa) fasta scores; FT opt: 540, z-score: 604.3, E(): 2.5e-26, (34.7% identity in FT 277 aa overlap). Contains Pfam match to entry PF00528 FT BPD_transp, Binding-protein-dependent transport systems FT inner membrane component and Prosite match to PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign. Also contains possible membrane spanning FT hydrophobic regions." FT /db_xref="GOA:Q9X9Y6" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9X9Y6" FT /protein_id="CAB46387.1" FT /translation="MITKEAPAAAPAPTPVAPAAARPGKKRPAWDEVPRWQIYLPLGIY FT LVFTLIPFYWILLFALRPTGSTSLVPWPMTTEHFEKVWTDRGFGTYFTNSVYVGLATLV FT MTTLVALAGGYALARFDFRIKRGFMLALLCSQFVPGALLLVPLFEIFAGLQMINSLGSV FT IIAETVFQLPLSIILISNFIKNVPYSLEEAAWVDGCGRFRAFRIVVLPLLRPGLIAVGS FT FAFVHSWNHFLFALMFLNNQSKQTIPVGLNSLMSADSVDLGALAAGGIVAAVPVVIVFA FT FIQKWLITGFSAGAVKG" FT misc_feature complement(201344..201568) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 72.20, E-value 1.1e-17." FT misc_feature complement(201479..201565) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS complement(202108..203043) FT /transl_table=11 FT /gene="SCO1887" FT /gene_synonym="SCI7.05c" FT /product="putative integral membrane transport protein" FT /note="SCI7.05c, possible integral membrane transport FT protein, len: 298aa; similar to many eg. TR:O51924 FT (EMBL:AF012836) inner membrane protein, MalF from the FT trehalose/maltose transport system of the hyperthermophilic FT archaeon Thermococcus litoralis (300 aa) fasta scores; opt: FT 681, z-score: 814.3, E(): 0, (37.5% identity in 285 aa FT overlap). Contains Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component and Prosite match to PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign. Also contains possible membrane spanning FT hydrophobic regions." FT /db_xref="GOA:Q9X9Y5" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9X9Y5" FT /protein_id="CAB46388.1" FT /translation="MAQAAAVAKPPAPPRRRRASATPRRLPYLLIGPAALLMLGFIAYP FT VISVFYYSLQEYNPTKPWRNGFAGFDNFVKIFTEDPVFWDTLVFSAKWVFVEVGLQLLF FT GLALALIVNQTFVGRGVGRAMVFSPWAVSGVLTSAIWVLLYNSQTGVTRYLADMGIGSY FT GTSWLSDTSTVFSAAVVADLWRGVPFFAILILADLQSVSKDLYEAAEVDGASRLKQFWH FT ITLPHLKDAIILSTLLRAVWEFNNVDLLYTLTGGGPAGETTTLPLYIANTSVDAHDFGY FT ASALTTVAFVILLFCSIVYLRLSKFGGENK" FT misc_feature complement(202222..202455) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 62.70, E-value 8.1e-15." FT misc_feature complement(202366..202452) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS complement(203165..204895) FT /transl_table=11 FT /gene="SCO1888" FT /gene_synonym="SCI7.06c" FT /product="putative dihydroxy-acid dehydratase" FT /note="SCI7.06c, probable dihydroxy-acid dehydratase, len: FT 576aa; similar to many eg. SW:ILVD_BACSU dihydroxy-acid FT dehydratase from Bacillus subtilis (557 aa) fasta scores; FT opt: 1153, z-score: 1290.1, E(): 0, (37.0% identity in 560 FT aa overlap). Contains Pfam match to entry PF00920 ILVD_EDD, FT Dehydratase family and Prosite match to PS00886 FT Dihydroxy-acid and 6-phosphogluconate dehydratases FT signature 1. Also contains a helix-turn-helix motif (+3.32 FT SD) 207-228aa." FT /db_xref="GOA:Q9X9Y4" FT /db_xref="InterPro:IPR000581" FT /db_xref="UniProtKB/TrEMBL:Q9X9Y4" FT /protein_id="CAB46389.1" FT /translation="MTPRKSPEELRSHQWYGTDGLRSFSHRARTRQLGYLPEEHLGKPV FT IAILNTWSDINPCHVHLRDRAQAVKRGVWQAGGFPLEFPVSTLSETFQKPTPMLYRNLL FT AMETEELLRSYPVDGAVLMGGCDKSTPALLMGAATVDLPAVFVPAGPMLPGHWRGETLG FT SGTDMWKYWDDKRAGLIGDCEMQELESGLARSPGHCMTMGTASTLTAAAEALGVTVPGA FT SSIPAVDSGHDRMAAAAGLRVVELVHRDRRLSDILTADAFEDAVTTVLGLGGSTNAVIH FT LIAMAGRAGVTLTLDDFDRIARTVPVLANVRPGGQTHLMEDFHFAGGLPGFLSRITDLL FT HLDRPTVAHDTLREQLDGALVHHDDVIRPRDNPVANEGGVAVLRGNLCPDGAVIKHIAA FT EPHLLKHTGPAVVFDDYKTMQRTINDPELGITADSVLVLRNAGPKGGPGMPEYGMLPIP FT DHLLKQGVRDMVRISDARMSGTSYGACVLHVAPESYVGGPLALVRTGDSITLDVGARTL FT HLGVDDEELERRRAAWTPPPARYERGYGALYNEQITQADTGCDFEFLARPGKVQDPYAG FT " FT misc_feature complement(203333..204679) FT /note="Pfam match to entry PF00920 ILVD_EDD, Dehydratase FT family, score 402.40, E-value 4.4e-117." FT misc_feature complement(204488..204520) FT /note="PS00886 Dihydroxy-acid and 6-phosphogluconate FT dehydratases signature 1." FT CDS complement(204892..205800) FT /transl_table=11 FT /gene="SCO1889" FT /gene_synonym="SCI7.07c" FT /product="putative dihydropicolinate synthase" FT /note="SCI7.07c, probable dihydropicolinate synthase, len: FT 302 aa; similar to many e.g. SW:DAPA_BACSU FT dihydropicolinate synthase from Bacillus subtilis (290 aa) FT fasta scores; opt: 280, z-score: 323.5, E(): 1.1e-10, FT (28.2% identity in 284 aa overlap). Contains Pfam match to FT entry PF00701 DHDPS, Dihydrodipicolinate synthetase FT family." FT /db_xref="GOA:Q9X9Y3" FT /db_xref="InterPro:IPR002220" FT /db_xref="UniProtKB/TrEMBL:Q9X9Y3" FT /protein_id="CAB46390.1" FT /translation="MTATFETQRAALADVVAIPVTPFAEDGTVDPATYRALLRRLLDGG FT ITTLTPNGNTGEFYALDPAERRLVTELTIEETGERADILVGVGHDVPTAVASARHARDL FT GASMVMVHQPVHPYVSQGGWVDYHRAIAEAVPELGVVPYIRNAQLTGARLADLADACPN FT VIGVKYAVPDASKFAAFARDAGLDRFVWVAGLAEPYAPSYFSAGATGFTSGLVNVAPAV FT SLNMIEALRSGDYPAAMKVWEQIRRFEELRAANGSANNVTVVKEALASLGLCRREVRPP FT SKPLPESERAEVAAIAAGWSI" FT misc_feature complement(204946..205707) FT /note="Pfam match to entry PF00701 DHDPS, FT Dihydrodipicolinate synthetase family, score 87.70, E-value FT 2.3e-22." FT CDS complement(205797..206465) FT /transl_table=11 FT /gene="SCO1890" FT /gene_synonym="SCI7.08c" FT /product="putative transcriptional regulator" FT /note="SCI7.08c, probable transcriptional regulator, len: FT 177aa; similar to many egs. TR:O50514 (EMBL:AL009204) FT putative transcriptional regulator from Streptomyces FT coelicolor (231 aa) fasta scores; opt: 272, z-score: 328.8, FT E(): 5.6e-11, 934.4% identity in 224 aa overlap) and FT SW:GNTR_BACSU transcriptional regulator of the gluconate FT operon of Bacillus subtilis (243 aa) fasta scores; opt: FT 217, z-score: 264.1, E(): 2.2e-07, (33.1% identity in 127 FT aa overlap). Contains Pfam match to entry PF00392 gntR, FT Bacterial regulatory proteins, gntR family. Also contains a FT helix-turn-helix motif (+3.07 SD) 35-56aa." FT /db_xref="GOA:Q9X9Y2" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9X9Y2" FT /protein_id="CAB46391.1" FT /translation="MTSVPTPIPSRTQYVLEEIKRRILTGRLTPGQALVETDLAAQFGV FT SKTPVREALKTLAGTGLVVMSQYKGVTVRMVDADMAREVYDVRLLLEPEALRRAVRREA FT SLDAAREALNRADRATDTAERSLANREFHRALYVPCGNPLLGRMLDEVRDQAALVSAVA FT WAADPSWEREAGEHQEILRLALAGDADGAARALHAHIASFVERAFPEAGNAAQEEDGQA FT " FT misc_feature complement(206247..206423) FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 63.00, E-value FT 6.3e-18." FT CDS complement(206634..207233) FT /transl_table=11 FT /gene="SCO1891" FT /gene_synonym="SCI7.09c" FT /product="hypothetical protein" FT /note="SCI7.09c, hypothetical protein, len: 199 aa; similar FT to TR:P71985 (EMBL:Z81360) hypothetical protein from FT Mycobacterium tuberculosis (189 aa) fasta scores; opt: 210, FT z-score: 248.3, E(): 1.7e-06, (32.4% identity in 182 aa FT overlap)." FT /db_xref="InterPro:IPR017520" FT /db_xref="UniProtKB/TrEMBL:Q9X9Y1" FT /protein_id="CAB46392.1" FT /translation="MTAETTTLDLGPQTRVLTRLADGVREDRLADPTPCPGLAVRNLLG FT HLTGLAVAFRDAARKDLGPTTDTSPEASVPDVGPGWREELAAALGELAEAWRDPEAWTG FT MTRAGGIDLPGEVAGAVVADELVIHGWDLARATGQEYAPDAAALRAAHGLLAAAAEESE FT RDQGMFGPVVAVPADAPLLERAVGLSGRDPDWTRTV" FT CDS 207375..208622 FT /transl_table=11 FT /gene="SCO1892" FT /gene_synonym="SCI7.10" FT /product="putative integral membrane efflux protein" FT /note="SCI7.10, possible integral membrane efflux protein, FT len: 415aa; similar to many egs. TR:CAB41206 FT (EMBL:AL049661) putative integral membrane efflux protein FT from Streptomyces coelicolor (500 aa) fasta scores; opt: FT 347, z-score: 354.0, E(): 2.2e-12, (29.7% identity in 408 FT aa overlap) and SW:TCR3_ECOLI tetracycline resistance FT protein from Escherichia coli (396 aa) fasta scores; opt: FT 241, z-score: 249.6, E(): 1.4e-06, (25.9% identity in 398 FT aa overlap). Contains possible membrane spanning FT hydrophobic regions." FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9X9Y0" FT /protein_id="CAB46393.1" FT /translation="MTTERTEHSAGRGGHRPLVRVLRDRDAALCLGGVVVSGFGTSALW FT LAAGVWVKDLTGSDGLAALCMLAMWAPTLVGPALGTLADRVRRRPLLIATGLLMSCLLL FT TLFAVDSREELWLVYAVLLVYGASGVVHDAAESALMAAAVDPGLLGDFNGLRLTANEGM FT KLVAPLAGAGLYAAYGGPGVALLDAATFVLAAAVYAALRVREAPPGRPAGNWRQHTAEG FT ARYLWGHPGLRPLVLAGGVTMLCAGVNGATAYAVVDALGHSPAYAGALYAVQGAGSVVA FT GLLAGWAVRRLGGRRFAAAGIALFAVAAAVRAAPYDAVALATSAAIGAGLPAVLIAALT FT AVQHETPGPLLGRVAATANSLVFAPNVLGLAAGAALVEPAGLWPLLPVVAAVLLGTAAV FT LAATRWPTGRRTPSAA" FT CDS complement(208611..209003) FT /transl_table=11 FT /gene="SCO1893" FT /gene_synonym="SCI7.11c" FT /product="putative lyase" FT /note="SCI7.11c, possible lyase, len: 130aa; similar to FT many egs. TR:O86701 (EMBL:AL031515) putative lyase from FT Streptomyces coelicolor (138 aa) fasta scores; opt: 153, FT z-score: 201.1, E(): 0.00072, (30.5% identity in 131 aa FT overlap) and SW:LGUL_ECOLI lactolylglutathione lyase from FT Escherichia coli (135 aa) fasta scores; opt: 111, z-score: FT 150.2, E(): 0.49, (28.3% identity in 138 aa overlap)." FT /db_xref="GOA:Q9X9X9" FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/TrEMBL:Q9X9X9" FT /protein_id="CAB46394.1" FT /translation="MELAQVRLLVTDFPSCYRYYRDVLGLKPQFESEDGPYAKFTPDGG FT AAGIALQDRAQMARVLGGLADEPAGHRSLVVLRVDDLDRYCEEITARGAEFVHGPAPMT FT DRMRVAHLVDPAGNLVELQEWLALRG" FT CDS complement(209088..210260) FT /transl_table=11 FT /gene="SCO1894" FT /gene_synonym="SCI7.12c" FT /product="hypothetical alanine-rich protein" FT /note="SCI7.12c, alanine-rich protein, len: 390aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X9X8" FT /protein_id="CAB46395.1" FT /translation="MKASAFVYPWDVNGDPEAPARVADLGVAQVTLAAAYHSTRALTPR FT HPRHRVVTAEHAAVLYPPDSARWQGRTLHPYASGDWAPGDAYGEAAAALAEAGLAVHTW FT VVLAHSSRLGAEHPHTSVVNAYGDRYPWAPCIAQPATRAYLTDLAAEAAVRPGARGTEL FT ESLGWYGLAHLHAHDKTGGVRLGDAGQYLMSLCFCPDCRAGYGGQGLDPDALAAAVRTA FT LEPVWRGAAPSDGGWAGVEKLLGAAPANATRAWRDDRARTLQEAAVSAVRAAAPDGFQV FT LLHADPVSHHCGANAGADPAHILSVADGVVVPCTGGAGLLTPFAEQAGAGTVLAANLTV FT VSGMGGSPRTLAADAARARDLGATELRLYHAGLASDGDLEEVRAGLAAFA" FT CDS complement(210257..211207) FT /transl_table=11 FT /gene="SCO1895" FT /gene_synonym="SCI7.13c" FT /product="putative dihydropicolinate synthase" FT /note="SCI7.13c, probable dihydropicolinate synthase, len: FT 316 aa; similar to many egs. SW:KDGD_PSEPU FT 5-dehydro-4-deoxyglutarate dehydratase from Pseudomonas FT putida (303 aa) fasta scores; opt: 731, z-score: 838.6, FT E(): 0, (41.1% identity in 302 aa overlap) and FT SW:DAPA_BACSU dihydropicolinate synthase from Bacillus FT subtilis (290 aa) fasta scores; opt: 374, z-score: 432.9, FT E(): 8.8e-17, (29.2% identity in 288 aa overlap). Contains FT Pfam match to entry PF00701 DHDPS, Dihydrodipicolinate FT synthetase family." FT /db_xref="GOA:Q9X9X7" FT /db_xref="InterPro:IPR002220" FT /db_xref="UniProtKB/Swiss-Prot:Q9X9X7" FT /protein_id="CAB46396.1" FT /translation="MTSAPLAARLTVPSGPLFFPVTAYGPDGGLDLDVYRTHVRRGVEA FT GAAAVFACCGTGEFHALTPEEFAACVRAAVEESAGRVPVLAGAGYGTALAVRYARLAEQ FT AGADGLLAMPPYLVLAGQEGLVRHYREVAAATPLPVIVYQRDNAVFTPESVVELARTDG FT VVGLKDGLGDLDLMQRIVSAVRTELPGEEFLYFNGLPTAEQTQLSYRALGVPLYSSAVF FT CFAPEIAVAFHRALREGDDATVHRLLDGFYRPFVELRARGRGYAVALVKAGVRLRGLDV FT GEVRTPLQEPAEEHVKQLVQIIERGQVLVEEGAGR" FT misc_feature complement(210335..211111) FT /note="Pfam match to entry PF00701 DHDPS, FT Dihydrodipicolinate synthetase family, score 251.30, FT E-value 1.3e-71." FT CDS 211442..212251 FT /transl_table=11 FT /gene="SCO1896" FT /gene_synonym="SCI7.14" FT /product="conserved hypothetical protein" FT /note="SCI7.14, unknown, len: 269aa; similar to many eg. FT SW:YTBQ_BACSU hypothetical protein from Bacillus subtilis FT (253 aa) fasta scores; opt: 262, z-score: 310.1, E(): FT 6.1e-10, (27.8% identity in 241 aa overlap)." FT /db_xref="GOA:Q9X9X6" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9X9X6" FT /protein_id="CAB46397.1" FT /translation="MPAPRTVLLTGAAGGLGTLMRELLPGHGYELRLLDLLPVEGEPDA FT IVADLADRDALREAVRGVDAIIHLAGISLEASFDKILAANIEGTYNLYEAAREEGVGRI FT VFASSNHAVGYTPRPQGDDPLIPIDTPRRPDTFYGLSKCFGEDLAQLYWDKHGIETVSV FT RIGSCFPEPTSVRMLSVWMSPADGARLFHAALTAENVGHTVVHGSSANTRLWWDLTSAR FT ALGYEPQDDSEPYAGKLVAEQGELDPGNPAHARLGGHFVTDPPIWPY" FT CDS 212535..213311 FT /transl_table=11 FT /gene="SCO1897" FT /gene_synonym="SCI7.15" FT /product="putative transcriptional regulator" FT /note="SCI7.15, probable transcriptional regulator, len: FT 258 aa; similar to many e.g. SW:GATR_ECOLI galacticol FT utilisation operon repressor from Escherichia coli (259 aa) FT fasta scores; opt: 399, z-score: 477.4, E(): 2.9e-19, FT (33.8% identity in 237 aa overlap). Contains Pfam match to FT entry PF00455 deoR, Bacterial regulatory proteins, deoR FT family. Also contains a helix-turn-helix motif (+3.53 SD) FT 26-47aa." FT /db_xref="GOA:Q9X9X5" FT /db_xref="InterPro:IPR001034" FT /db_xref="UniProtKB/TrEMBL:Q9X9X5" FT /protein_id="CAB46398.1" FT /translation="MSTRTRTTEERRHEIVRVARATGSVDVTALAAELGVAKETVRRDL FT RALEDHGLVRRTHGGAYPVESAGFETTLAFRATSHVPEKRRIASAAVELLGDAETVFVD FT EGFTPQLIAEALPRDRPLTVVTASLPVAGALAEAGDTSVLLLGGRVRSGTLATVDHWTT FT KMLAGFVIDLAYIGANGISREHGLTTPDPAVSEVKAQAVRAARRTVFAGAHTKFGAVSF FT CRFAEVGALEAIVTSTLLPSAEAHRYSLLGPQIIRV" FT misc_feature 212565..213245 FT /note="Pfam match to entry PF00455 deoR, Bacterial FT regulatory proteins, deoR family, score 176.50, E-value FT 4.2e-49." FT CDS 213414..214784 FT /transl_table=11 FT /gene="SCO1898" FT /gene_synonym="SCI7.16" FT /product="putative substrate binding protein" FT /note="SCI7.16, possible sugar binding protein, len: 456aa; FT similar to many eg. TR:O30831 (EMBL:AF018073) periplasmic FT sorbitol binding protein from Rhodobacter sphaeroides (436 FT aa) fasta scores; opt: 1203, z-score: 1347.3, E(): 0, FT (42.8% identity in 423 aa overlap). Contains possible FT N-terminal signal sequence." FT /db_xref="GOA:Q9X9X4" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:Q9X9X4" FT /protein_id="CAB46399.1" FT /translation="MRTQSRRRPRATLAMAAAGTLLAPLLTGCWVGAGGAGSGGNAINV FT LMVNNPQMVELQKLTADHFTKETGIKVNFTVLPENDVRDKISQDFANQAGQYDAATLSN FT YEIPIYARNDWLHEMDSYVAKDPAYDEQDVLGPMRESLTADDGKLYGQPFYGESSFLMY FT RKDLFAKAGLTMPEHPTWTQVASFAEKLDGSEPGMKGICLRGLPGWGELMAPLTTVVNT FT FGGTWFDQDWQARLDSPEWEKATKFYVDLVREHGESGAAQSGFAECLNNMTQGKVAMWY FT DATSAAGSLDAADSPVKGKIGYAPAPVEKTDSSGWLYTWAWGIQKASRNSDKAWKFVSW FT ASSKEYEQLVGDEIGWSNVPAGKRASTYENPAYVKEAAAFQEMTRKAIEGARPKDPGVQ FT PRPAPGIQFVGIPEFTDLGTKVSQEISAAIAGRQSVEEALKKSQQLAEQISEEYEGR" FT CDS 214781..215725 FT /transl_table=11 FT /gene="SCO1899" FT /gene_synonym="SCI7.17" FT /product="putative integral membrane sugar transport FT protein" FT /note="SCI7.17, possible integral membrane sugar transport FT protein, len: 314aa; similar to many eg. TR:O30832 FT (EMBL:AF018073) sorbitol/mannitol transport inner membrane FT protein from Rhodobacter sphaeroides (290 aa) fasta scores; FT opt: 722, z-score: 829.0, E(): 0, (40.6% identity in 276 aa FT overlap). Contains Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component and Prosite match to PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign. Also contains possible membrane spanning FT hydrophobic regions." FT /db_xref="GOA:Q9X9X3" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9X9X3" FT /protein_id="CAB46400.1" FT /translation="MTATTTAPSAAPEHPRPAVRPPSNRLRAWATRAPLLPALIFMIVV FT TQLPFVATLVISFFDWNALYPDARSFTGFANYGDVLSDPALRKSVWTTILLTVAVVLVS FT LVLGLALALLLDRRFKGRGVVRTLLIAPFLVVPVAAALLWKHVLYNPEYGLLNGLLHYV FT GGPQPDWISNTPLLAVEASLVWQWTPFMMLILLAGLQSRDQQQIEAARVDGAGDWQIFV FT HLTLPHLRRYLELGALLGSIYIVQNFDAVFTITSGGLGTANLPYTVYQSFYQAHENGLA FT SAAGVLVVIGSIIIATFALRVVSSLFREEVGRA" FT misc_feature 215372..215599 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 66.00, E-value 7.8e-16." FT misc_feature 215375..215461 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS 215722..216600 FT /transl_table=11 FT /gene="SCO1900" FT /gene_synonym="SCI7.18" FT /product="putative integral membrane sugar transport FT protein" FT /note="SCI7.18, possible integral membrane sugar transport FT protein, len: 292aa; similar to many eg. TR:O30833 FT (EMBL:AF018073) sorbitol/mannitol transport inner membrane FT protein from Rhodobacter sphaeroides (276 aa) fasta scores; FT opt: 659, z-score: 770.4, E(): 0, (40.6% identity in 276 aa FT overlap). Contains Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component. Also contains possible membrane spanning FT hydrophobic regions." FT /db_xref="GOA:Q9X9X2" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9X9X2" FT /protein_id="CAB46401.1" FT /translation="MSATAVRPVVTDAKPPVRTRRRAGAGLGLVAWLVGIVFFLPIAWM FT ALTSFHSESDAATNPPSFAASLTLDGYREFFGAGGGASPWPALVNSAVASIASTLFVLV FT LALPAAYALSIRPVKKWTDVLFFFLSTKMLPVVAGLLPIYLFAKNTDMLDNIWLLVILY FT TSMNLPIAVWMMQSFLAEVPVAIIEAARVDGAKLPTILVRVVAPIALPGIAATSLICFI FT FSWNELLFARVLTGVVAETAPVFLTGFITSQGLFLAKVCAASLVISLPVLAAGFAAQDK FT LVQGLSLGAVK" FT misc_feature 216253..216480 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 35.20, E-value 1.5e-06." FT CDS 216597..217586 FT /transl_table=11 FT /gene="SCO1901" FT /gene_synonym="SCI7.19" FT /product="putative zinc-binding dehydrogenase" FT /note="SCI7.19, probable zinc-binding dehydrogenase, len: FT 329 aa; similar to many e.g. SW:DHSO_BACSU sorbitol FT dehydrogenase from Bacillus subtilis (352 aa) fasta scores; FT opt: 552, z-score: 626.6, E(): 1.4e-27, (30.1% identity in FT 345 aa overlap). Contains Pfam match to entry PF00107 FT adh_zinc, Zinc-binding dehydrogenases and Prosite match to FT PS00059 Zinc-containing alcohol dehydrogenases signature" FT /db_xref="GOA:Q9X9X1" FT /db_xref="HSSP:1F8F" FT /db_xref="InterPro:IPR013154" FT /db_xref="UniProtKB/TrEMBL:Q9X9X1" FT /protein_id="CAB46402.1" FT /translation="MKAAVIESVGRAVVTEVPDPTPGPREVVVEVAACGLCGTDLHILQ FT GEFAPKLPIVPGHEFAGAVVGVGAQVTEVAVGDQVAVDPSLYCYECRYCRTGHNNLCER FT WAAIGVTTAGGAAQYAVAPVANCVKLPEHVRTQDAALIEPLSCAVRGYDVLQSRLGAHV FT LIYGSGTMGLMMLELAKRTGAASVDMVDLNPARLETARGLGVSASAATPDELDRPQGWD FT LVIDATGNAAAIQDGLDRVAKAGTFLQFGVADYATRVQIDPYRIYNQEITITGSMAVLH FT SYERAAELFANGVLDPDVFISDRIELARYPQALEQFAAGVGRKIVVVP" FT misc_feature 216615..217580 FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score 218.50, E-value 9.8e-62." FT misc_feature 216765..216809 FT /note="PS00059 Zinc-containing alcohol dehydrogenases FT signature." FT CDS 217605..217994 FT /transl_table=11 FT /gene="SCO1902" FT /gene_synonym="SCI7.20" FT /product="hypothetical hydrophilic protein" FT /note="SCI7.20, unknown, hydrophilic, len: 129aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X9X0" FT /protein_id="CAB46403.1" FT /translation="MPPPGEFEDEAVQAERRGSGGGSPQGREGTERDGKGRGGGAKTRG FT NAAPTTRTLPRMPKPNGFAYTATASGTVHITHHNRPATTLNGSRAARFLEEVTAGDPQL FT VMARWTGTYKHGNERTARNHPRNRR" FT CDS 218080..219279 FT /transl_table=11 FT /gene="SCO1903" FT /gene_synonym="SCI7.21" FT /product="putative transport associated protein" FT /note="SCI7.21, possible transport associated protein, len: FT 399aa; appears to be the last gene in a possible sugar FT transport operon, similar to many eg. TR:CAB38155 FT (EMBL:AL035591) putative export associated protein from FT Streptomyces coelicolor (192 aa) fasta scores; opt: 475, FT z-score: 388.5, E(): 2.6e-14, (43.6% identity in 188 aa FT overlap) and TR:CAA22211 (EMBL:AL034355) hypothetical FT protein from Streptomyces coelicolor (482 aa) fasta scores; FT opt: 534, z-score: 428.9, E(): 1.5e-16, (42.3% identity in FT 260 aa overlap) and SW:TERZ_SERMA tellurium resistance FT protein, TerZ from Serratia marcescens (193 aa) fasta FT scores; opt: 429, z-score: 352.8, E(): 2.6e-12, (47.6% FT identity in 185 aa overlap)." FT /db_xref="GOA:Q9X9W9" FT /db_xref="InterPro:IPR003325" FT /db_xref="UniProtKB/TrEMBL:Q9X9W9" FT /protein_id="CAB46404.1" FT /translation="MTPGSNIPLSAARVTVDVAAPVRLDVSGLLLTADGKVRSDDDFIF FT YNQPTGQGVTYRSGGGSAPDAIVVDTSAVPPGIEKIVVTASPDAAGQTFQGIEPTATIR FT NADDNAVLATFTPPQLGTETALVIVEVYLRNGAWKARAVGQGYSNGLAGIATDFGVTVE FT EPAAPATPPQPQAVTPPPPPAAAPTMPAAPPAPPAAPPAPAPGTGKINLDKGRVSLQKN FT QTVSLVKGGRPVLSQVKMGLGWEPAYRGKDIDLDASVIAYGPQRNHIDSCYFGKLSIVN FT GAIKHSGDNLTGEGGGDDEVIVVDLGRLPQEVSGLVFTVNSFSGQKFTEVAKAYCRLID FT AASGEELVRFDLTSAEPQTGVMMAKLIRQYSGEWEMTAIGDFVKSRTVRGMVKPAAQAL FT " FT CDS complement(219319..219927) FT /transl_table=11 FT /gene="SCO1904" FT /gene_synonym="SCI7.22c" FT /product="putative transcriptional regulator" FT /note="SCI7.22c, probable transcriptional regulator, len: FT 202 aa; similar to many e.g. TR:CAA22690 (EMBL:AL035159) FT putative transcriptional regulator from Mycobacterium FT leprae (189 aa) fasta scores; opt: 353, z-score: 418.1, FT E(): 5.9e-16, (38.6% identity in 189 aa overlap) and FT TR:O24739 (EMBL:AB001609) butyrolactone synthesis FT transcriptional regulator in Streptomyces virginiae (216 FT aa) fasta scores; opt: 191, z-score: 231.1, E(): 1.5e-05, FT (35.0% identity in 163 aa overlap). Contains Pfam match to FT entry PF00440 tetR, Bacterial regulatory proteins, tetR FT family. Also contains a helix-turn-helix motif (+5.38 SD) FT 46-67aa." FT /db_xref="GOA:Q9X9W8" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9X9W8" FT /protein_id="CAB46405.1" FT /translation="MPGRLPAVQGGAVAQVRPMRADARRNRERLLAVAAQAFAEHGEGA FT SLDDIARRAGVGVGTLYRHFPTRQALLEAAYLERLEAIAARADVIAAARPPGAALMAWL FT DELAVGMLQVRGLKALLGTAVTGGGPACGDCVRGAATRLVRAAQEAGALRADVEPVEVL FT RLLHGVVTAAEAADEVDGTAVRRYLSLLMEGLGQGPGQV" FT misc_feature complement(219703..219840) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 45.90, E-value FT 5.1e-11." FT CDS complement(219929..221530) FT /transl_table=11 FT /gene="SCO1905" FT /gene_synonym="SCI7.23c" FT /product="hypothetical protein" FT /note="SCI7.23c, unknown, len: 533aa;" FT /db_xref="GOA:Q9X9W7" FT /db_xref="InterPro:IPR008858" FT /db_xref="UniProtKB/TrEMBL:Q9X9W7" FT /protein_id="CAB46406.1" FT /translation="MARFNTRTAKAQPTSRVTSTGRVLRTYEGGRGTERDARSELYLLS FT VANFVSQQTFYESGAARDDRFAALVRELAVADPSWTAGLLGWLRGEGNLRTASIVGAAE FT YVKARLDSGVTDGPSNRQVIASVLRRPDEPGELLAYWTATYGRAVPKPVKRGIADAVRR FT IYHGKSLLKYDTASKGYRFGDILNLVHAAPDPDKPWQGELFQYALDRRHNPDTAVPPAS FT NRVLTAHRELMALPVPERRAVVTAPDGAERLAAAGITWEMLAGWLQGPMDKAAWEAVIP FT SMGAMALLRNLRNLDEAGVSDEVAARVAARISDPAEVARSRQFPFRYLAAYRHAPSLRW FT SYPLEQALGHSLANVPALGGRTLVLVDRSGSMFYSRMSDRSELTRADAAAVFGTALALR FT AADADLVEFGSSSNRVTYREGESVLKVLGRFRNLGGTDTTEAVRRHYEKHDRVLIVTDE FT QYAYSRYGDPTEQVPAHVPVYTWNLAGYRAGHGPSGRANRHTFGGLSDAAFRMVPLLEA FT GRDADWPWDARDEHAR" FT misc_feature 222024..222029 FT /note="Cleavage site for AseI restriction endonuclease FT AT*TAAT." FT misc_feature complement(222024..222029) FT /note="Cleavage site for AseI restriction endonuclease FT AT*TAAT." FT CDS complement(222029..223501) FT /transl_table=11 FT /gene="SCO1906" FT /gene_synonym="SCI7.24c" FT /product="putative secreted protein" FT /note="SCI7.24c, putative secreted protein, len: 490 aa; FT similar to TR:O69840 (EMBL:AL023517) hypothetical protein FT from Streptomyces coelicolor (465 aa) fasta scores; opt: FT 1059, z-score: 1178.4, E(): 0, (48.1% identity in 495 aa FT overlap). Contains possible N-terminal region signal FT peptide sequence" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q9X9W6" FT /protein_id="CAB46407.1" FT /translation="MSLTRRDFAGRSALTGAGVVLAGSVGALATAPNALASTDTDSVGA FT EHDGHDHHHGHGHGGVGYGPLLPDPDGILALPAGFRYEIITYSGRTKLESGEYTPSNHD FT GTAAFDGPRGTTLLVNNHELGGHRDDWPHPVPLTEGLVYDPAAAGGCTVVEVRRGGHVA FT EWVGIAGTATNCAGGSTPWGTWLTCEETEDRAGEEGMTKDHGYVFEVDPEDRRANREPK FT PVKALGRYAHEAVVIDPKRGHAYLTEDASGPNGLLYRWTPPEHFRHGRGRLRTLADDAG FT VLQAFKCFDSGGKFVDDLSRATRTGTVYGVDWVDVPDRDAQTTSVRKQFAAGEVTRARK FT LEGMWWADGGAYVVSSFARDESPGRPHDGQVWFYDPKRRTLTLKVLLGVNADPSADGAF FT DGPDNITVSPYGGLVIAEDGDGVQHLFGATDSGRTYPIARNELNLGTEDDPEYSEFTGV FT TFSPDGRTLYANIQTPGIMLAITGPWKRQKRR" FT CDS complement(223786..225213) FT /transl_table=11 FT /gene="SCO1907" FT /gene_synonym="SCI7.25c" FT /product="conserved hypothetical protein" FT /note="SCI7.25c, unknown, len: 475aa; contains Prosite FT match to PS00213 Lipocalin signature. Similar to TR:Q9RJ26 FT (EMBL:AL132644) SCI8.27C hypothetical protein from FT Streptomyces coelicolor (447 aa) fasta scores; opt: 380, FT Z-score: 401.6, E(): 9.7e-15, 32.114% identity (38.257% FT ungapped) in 492 aa overlap." FT /db_xref="InterPro:IPR002345" FT /db_xref="UniProtKB/TrEMBL:Q9X9W5" FT /protein_id="CAB46408.1" FT /translation="MSDSSTLPPARLRPEAELARDALSAPVLARAARLARWADAGTRVD FT AGGGLVEEQLPAAAEQLGLSGDDAAAHASEAWRIAVDTGLVEITDEETGTVAAGEDLAL FT LTGGSPQDVLGVWLTALEAVLADASVPDLDDLVDAMAEGGEVDLSSLDWDPEAESDFLD FT GVLGNLYLLTVGEEGPGEAPVPLPALAASVIVPSDMGEPSNEVLEQVSDAMMRLDDQFR FT LLEPVGLVEYQPVDEALMADADEEPAAPVDEADVTRYGMVRLTPLGLYGLRARLLDAGF FT EAPAVGDLSDKGADALLDGTAPFPPAAAHAETELWLAGRSPLDAARELLAAARGTDPGA FT PLRRLRCQQALSLVGAEAEPALREVLDDAELGGLARVWLTEHGARDVPPPPQEMVFWLT FT IDTVAAQLAAEGNSEELRALVEGLARQHSGFFDTVWRVEHPATPEVLEAMGRLHPDKKV FT AKEARKAAFKARSQQGG" FT misc_feature complement(224854..224895) FT /note="PS00213 Lipocalin signature." FT CDS 225430..227271 FT /transl_table=11 FT /gene="SCO1908" FT /gene_synonym="SCI7.26" FT /product="putative large secreted protein" FT /note="SCI7.26, possible large secreted protein, len: FT 613aa; similar to TR:O83555 (EMBL:AE001229) hypothetical FT protein from Treponema pallidum (622 aa) fasta scores; opt: FT 478, z-score: 514.7, E(): 2.4e-21, (34.0% identity in 633 FT aa overlap). Contains possible N-terminal signal sequence." FT /db_xref="InterPro:IPR005135" FT /db_xref="UniProtKB/TrEMBL:Q9X9W4" FT /protein_id="CAB46409.1" FT /translation="MASKSSARLAALTVAAVCSAASTVVLTTPAHAASAAAGPVRIHDV FT QGSTRLSPYAGEQVTDVAGIVTGVRGYGSSKGFWMQDPLPDADPATSEGVFVFTSRAPE FT VAVGDAVTVSGTVSEYVPGGTSSGNQSLTEITRPTVTVVSGGNAIPAATTVSARSVPRA FT YAPEGDGAANGSVNALPLRPGTYALDYYESLEGMNVRVADARVVGASDPYTELWVTVKP FT WENPNRRGGTVYGSYDDQNTGRLQIQSLGKPADFPAADVGDTLAGTTAGPLDYNQYGGY FT TLVASEIGALESGGTERESTRRQSARELAVATYNVENLDPSDDTFTAHAETIVHRLKSP FT DIVSLEEIQDNNGATDDGTVAADATVGRLIDAIVAAGGPRYDWRGIDPVDKADGGQPGG FT NIRQAFLFNPERVSFTDRAGGDATTATGVRKVRGKAALTHSPGRVDPANEAWEDSRKPL FT AGEFVFRGRTVFVVANHFNSKGGDQGLTAQYQPPSRGSETQRHAQAKVVNTFVKEILAA FT QKNADVVALGDINDFEFSRTARILEGDGALWSAVKSLPRSERYSYVYQGNSQVLDQILV FT SPSVRRGGHLSYDSVHVNAEFHDQISDHDPQVLRFRP" FT CDS complement(227302..228009) FT /transl_table=11 FT /gene="SCO1909" FT /gene_synonym="SCI7.27c" FT /product="hypothetical protein" FT /note="SCI7.27c, unknown, len: 235aa;" FT /db_xref="GOA:Q9X9W3" FT /db_xref="InterPro:IPR007138" FT /db_xref="UniProtKB/TrEMBL:Q9X9W3" FT /protein_id="CAB46410.1" FT /translation="MTRRTDTHPDLARPDASAPFFSTWRVGTPERQRQTVDAIARTWEI FT RPWPAEDLRGYHVYTGHDGSTLLHHSQWASEQAYEAFVKTHRQERVDEIDTAVPGIERL FT GLGRYRRYRSAAREDRAAVVPGCIVIVDIEFEGPDPDRQRAWVDAVFEALESEPHPHPG FT GISAHFHLSTDGTRVLNYAEWESAQAHLDALAAPGDGVGSTTPQWERVQNWPGLTGGGR FT VSRYDHALGLVPR" FT CDS complement(228167..228664) FT /transl_table=11 FT /gene="SCO1910" FT /gene_synonym="SCI7.28c" FT /product="putative alanine-rich protein" FT /note="SCI7.28c, possible alanine-rich protein, len: 165 FT aa; contains 3 x H**H*KAGRA* repeat region. Largely FT hydrophilic. Contains possible hydrophobic membrane FT spanning region at C-terminal domain" FT /db_xref="UniProtKB/TrEMBL:Q9X9W2" FT /protein_id="CAB46411.1" FT /translation="MTDATSRDGSRSGSTEQPVGGAKGPDELRRQIEQTRGQLGDTVEE FT LAGKADVKGRAKARAADLKDKAGAMSVQLRSSAAHAGHTVHDKAGRAGHAAHDKAGRAG FT HAAHAKAGRAKSAAEPHARPGRARGAVRAGLGHPRVVLAAGAAAGVVVAASLVRRRQHG FT HC" FT repeat_region 228320..228418 FT CDS complement(228661..229158) FT /transl_table=11 FT /gene="SCO1911" FT /gene_synonym="SCI7.29c" FT /product="putative integral membrane protein" FT /note="SCI7.29c, possible integral membrane protein, len: FT 165aa; similar to others from Mycobacterium tuberculosis FT and Streptomyces coelicolor egs. TR:O69637 (EMBL:AL022121) FT hypothetical protein from Mycobacterium tuberculosis (172 FT aa) fasta scores; opt: 194, z-score: 223.8, E(): 3.9e-05, FT (30.6% identity in 134 aa overlap) and SW:CAA22031 FT (EMBL:AL033505) putative membrane protein from Streptomyces FT coelicolor (205 aa) fasta scores; opt: 187, z-score: 215.2, FT E(): 0.00012, (33.8% identity in 130 aa overlap). Contains FT possible membrane spanning hydrophobic region. Also FT contains a helix-turn-helix motif (+3.21 SD) 39-60aa." FT /db_xref="InterPro:IPR009937" FT /db_xref="UniProtKB/TrEMBL:Q9X9W1" FT /protein_id="CAB46412.1" FT /translation="MRVPAGVAPFGAGYPGCSEPRGGGNTVTGTMHTRPVRDEQHSVGE FT LVGQATEQLSRLVRQEVALAKMELAEKGKRAGRGGGMLGAAGAIAYVGLFALAGTATAA FT LSLVLPVWAAALIVTAALFVIAGVLAMAGRAQLRRAVPPKPEETLGSVRADVDQIRERA FT HR" FT CDS 229226..230179 FT /transl_table=11 FT /gene="SCO1912" FT /gene_synonym="SCI7.30" FT /product="putative dihydrodipicolinate synthase" FT /note="SCI7.30, probable dihydrodipicolinate synthase, len: FT 317 aa; similar to many egs. TR:O86841 (EMBL:AL031260) FT putative dihydrodipicolinate synthase from Streptomyces FT coelicolor (299 aa) fasta scores; opt: 1018, z-score: FT 1116.9, E(): 0, (56.4% identity in 305 aa overlap) and FT SW:DAPA_BRELA dihydrodipicolinate synthase from FT Brevibacterium lactofermentum (301 aa) fasta scores; opt: FT 800, z-score: 879.6, E(): 0, (46.6% identity in 292 aa FT overlap). Contains Pfam match to entry PF00701 DHDPS, FT Dihydrodipicolinate synthetase family and Prosite matches FT to PS00665 Dihydrodipicolinate synthetase signature 1 and FT PS00666 Dihydrodipicolinate synthetase signature 2." FT /db_xref="GOA:Q9X9W0" FT /db_xref="HSSP:1DHP" FT /db_xref="InterPro:IPR002220" FT /db_xref="UniProtKB/Swiss-Prot:Q9X9W0" FT /protein_id="CAB46413.1" FT /translation="MELHCLAADTTPMTTDDDSAPFGRSLCAMVTPFTGSGALDLDGAQ FT RLADRLVARGCDGLVLSGTTGESPTTTDAEKAALVTAVREAVGDRAALVAGVGTADTRH FT TVELALAAEKAGADGLLVVAPYYSRPPQDALEAHFREVADASGLPVMLYDIPGRTGTRI FT EPDTVVRLAAHPRIVAVKDCAYDLLGTQKVLSRTGLAYYAGCDEQILPLYAIGAAGYVS FT TVANVVPELFRAVLDAFDAGDTGRAALLQRRAVPLVESMMAAGLPGTVTAKALLGALGL FT PAGPVRAPLRSADRETTAGLLAAYGELAADAGQSQA" FT misc_feature 229349..230104 FT /note="Pfam match to entry PF00701 DHDPS, FT Dihydrodipicolinate synthetase family, score 261.60, FT E-value 1.1e-74." FT misc_feature 229397..229450 FT /note="PS00665 Dihydrodipicolinate synthetase signature 1." FT misc_feature 229682..229774 FT /note="PS00666 Dihydrodipicolinate synthetase signature 2." FT CDS complement(230164..230430) FT /transl_table=11 FT /gene="SCO1913" FT /gene_synonym="SCI7.31c" FT /product="putative small membrane protein" FT /note="SCI7.31c, possible small membrane protein, len: 88 FT aa; contains possible hydrophobic membrane spanning region" FT /db_xref="UniProtKB/TrEMBL:Q9X9V9" FT /protein_id="CAB46414.1" FT /translation="MTPENTPETPNERVRAAARRLLAGAGAAVLVCCGSVWAAGAAHAD FT ETTTGSHNGPRVGLLNVHVGQIDDPAEDVLEHTLLFGDGYAWD" FT CDS 230569..230739 FT /transl_table=11 FT /gene="SCO1914" FT /gene_synonym="SCI7.32" FT /product="hypothetical protein" FT /note="SCI7.32, unknown, len: 56aa;" FT /db_xref="UniProtKB/TrEMBL:Q9X9V8" FT /protein_id="CAB46415.1" FT /translation="MARGVPGGYRIRDTKGGRWWGDLYELCPDDLLTELNGAADRARVT FT ALLKRYRALKR" FT CDS 230795..231523 FT /transl_table=11 FT /gene="SCO1915" FT /gene_synonym="SCI7.33" FT /product="hypothetical protein" FT /note="SCI7.33, unknown, len: 242aa;" FT /db_xref="GOA:Q9X9V7" FT /db_xref="UniProtKB/TrEMBL:Q9X9V7" FT /protein_id="CAB46416.1" FT /translation="MPEKTPDKTPTGPTLAEVMAELAGLEDPRIRAVNEKHGDDHGVHL FT TKLRALAKRLKTQPELARTLWATDDTAARLLALLVCRPKSYGRDELDTMLRQARTPKVH FT DWLVNYVVKKNPHAEELRVAWTANPDPVVASAGWALTTERVTRNPAGLDLPALLDTVES FT EMSDAPDRLQWAMNHCLARIGIDHPEHRARALTIGERLGVLKDYPTPPGCTSPYAPAWI FT TEIVRRQQEHAAVKSSPTDT" FT CDS complement(231574..232563) FT /transl_table=11 FT /gene="SCO1916" FT /gene_synonym="SCI7.34c" FT /product="putative transferase" FT /note="SCI7.34c, possible transferase, len: 329 aa; similar FT to many e.g. TR:BAA75911 (EMBL:AB024601) FT tetrahydrodipicolinate N-succinyltransferase from FT Pseudomonas aeruginosa (344 aa) fasta scores; opt: 1004, FT z-score: 1062.7, E(): 0, (54.4% identity in 307 aa FT overlap). Contains possible N-terminal signal sequence." FT /db_xref="GOA:Q9X9V6" FT /db_xref="InterPro:IPR019875" FT /db_xref="UniProtKB/TrEMBL:Q9X9V6" FT /protein_id="CAB46417.1" FT /translation="MTDTTAPRTSGAVAAGLATIAADGTVLDTWFPAPELSDEPGPSGT FT ERLTAEQAAELLGGGATAAVGPDARRGVEVVAVRTVISSLDEKPVDTHDVYLRLHLLSH FT RLVKPHGQSLDGIFAHLANVAWTSLGPVAVDDIEKVRLNARAEGLHLQVTSIDKFPRMT FT DYVAPKGVRIADADRVRLGAHLSAGTTVMHEGFVNFNAGTLGTSMVEGRISAGVVVGDG FT SDIGGGASTMGTLSGGGNVRIVIGERCLVGAEAGVGIALGDECVVEAGLYVTAGTRVTM FT PDGQVVKARELSGASNILFRRNSVTGTVEARPNNAVWGGLNEILHSHN" FT CDS complement(232573..233166) FT /transl_table=11 FT /gene="SCO1917" FT /gene_synonym="SCI7.35c" FT /product="conserved hypothetical protein" FT /note="SCI7.35c, unknown, len: 197aa; similar to many eg. FT TR:P95092 (EMBL:Z83866) hypothetical protein from FT Mycobacterium tuberculosis (202 aa) fasta scores; opt: 398, FT z-score: 482.3, E(): 1.6e-19, (40.3% identity in 191 aa FT overlap)." FT /db_xref="GOA:Q9X9V5" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9X9V5" FT /protein_id="CAB46418.1" FT /translation="MPRRHDPERRQRIIDAAIRVVGQKGIAGLSHRTVAAEADVPLGST FT TYHFATLDDLMVAALRQANEGFARVVAAHPALSDPEADLSGELARVLGEWLGGDRTGVE FT LEYELYLAALRRPALRPVAAEWAEGVGALLAARTDPTTARALVAVLDGICLQVLLTDTP FT YDEEYAREVLTRLIPVPATRDGRGPGSHPPATAG" FT CDS complement(233166..233486) FT /transl_table=11 FT /gene="SCO1918" FT /gene_synonym="SCI7.36c" FT /product="putative integral membrane protein" FT /note="SCI7.36c, possible integral membrane protein, len: FT 106aa; similar to many proposed to be involved in FT resistance mechanisms eg. SW:EMRE_ECOLI viologen resistance FT protein from Escherichia coli (110 aa) fasta scores; opt: FT 313, z-score: 392.7, E(): 1.5e-14, (51.0% identity in 100 FT aa overlap). Contains Pfam match to entry PF00893 DUF7, FT Integral membrane protein." FT /db_xref="GOA:Q9X9V4" FT /db_xref="HSSP:1S7B" FT /db_xref="InterPro:IPR000390" FT /db_xref="UniProtKB/TrEMBL:Q9X9V4" FT /protein_id="CAB46419.1" FT /translation="MGYLLLAGAIAAEVAGTTAMKYSEGFSRLVPSLLTALAYVLSFAL FT LAQTLKILAVGTAYAIWAGVGTAAIATIGVAFMGEGMTLTKAAGIALIIIGVVVLNLGG FT AH" FT misc_feature complement(233208..233486) FT /note="Pfam match to entry PF00893 DUF7, Integral membrane FT protein, score 117.60, E-value 2.3e-31." FT CDS complement(233605..233937) FT /transl_table=11 FT /gene="SCO1919" FT /gene_synonym="SCC22.01c" FT /gene_synonym="SCI7.37c" FT /product="conserved hypothetical protein" FT /note="SCC22.01c, partial CDS, conserved hypothetical FT protein, len: >75aa; similar to many other hypothetical FT proteins eg. TR:O53157 (EMBL:AL021184) hypothetical protein FT from Mycobacterium tuberculosis (115 aa) fasta scores; opt: FT 284, z-score: 392.0, E(): 1.7e-14, (61.3% identity in 80 aa FT overlap)." FT /note="SCI7.37c, partial CDS, unknown, len: >74aa; similar FT to TR:O53157 (EMBL:AL021184) hypothetical protein from FT Mycobacterium tuberculosis (115 aa) fasta scores; opt: 375, FT z-score: 536.1, E(): 1.6e-22, (70.1% identity in 77 aa FT overlap)." FT /db_xref="InterPro:IPR002744" FT /db_xref="UniProtKB/TrEMBL:Q8CK13" FT /protein_id="CAD55183.1" FT /translation="MSETLEMKPASEEELREALMDVVDPELGIDVVNLGLIYGIHVDDA FT NIATVDMTLTSAACPLTDVIEDQAKSATDGLVSELRINWVWMPPWGPDKITDDGREQLR FT ALGFNV" FT CDS complement(233934..234404) FT /transl_table=11 FT /gene="SCO1920" FT /gene_synonym="SCC22.02c" FT /product="conserved hypothetical protein" FT /note="SCC22.02c, conserved hypothetical protein, len: FT 156aa; similar to many other hypothetical protein eg. FT TR:O53156 (EMBL:AL021184) hypothetical protein from FT Mycobacterium tuberculosis (162 aa) fasta scores; opt: 569, FT z-score: 685.8, E(): 7.2e-31, (56.3% identity in 158 aa FT overlap) and to SW:NIFU_BACSU (EMBL:Z99120) Bacillus FT subtilis NifU-like protein NifU, 147 aa; fasta scores: opt: FT 439 Z-score: 527.7 E(): 9.3e-22; 45.517% identity in 145 aa FT overlap" FT /db_xref="GOA:Q9XAD6" FT /db_xref="InterPro:IPR011341" FT /db_xref="UniProtKB/TrEMBL:Q9XAD6" FT /protein_id="CAB50745.1" FT /translation="MKLDSMYQEVILDHYKNPHGRGLRDGDAEVHHVNPTCGDEITLRV FT KYDGSTISDVSYEGQGCSISQASASVLNDLLVGKDLAQAQRIQETFLELMQSKGRIEPD FT DAMEEVLEDAVAFAGVSKYPARVKCALLSWMAWKDATAQALDGADAEKETTA" FT CDS complement(234422..235678) FT /transl_table=11 FT /gene="SCO1921" FT /gene_synonym="SCC22.03c" FT /product="putative aminotransferase" FT /note="SCC22.03c, possible aminotransferase, len: 418 aa; FT similar to many proposed aminotransferase/nifS-like FT proteins e.g. TR:Q49690 (EMBL:U00013) NifS from FT Mycobacterium leprae (418 aa) fasta scores; opt: 1438, FT z-score: 1673.0, E(): 0, (53.4% identity in 414 aa FT overlap). Contains Pfam match to entry PF00266 aminotran_5, FT Aminotransferases class-V." FT /db_xref="GOA:Q9XAD5" FT /db_xref="HSSP:1KMJ" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/Swiss-Prot:Q9XAD5" FT /protein_id="CAB50746.1" FT /translation="MTQLPGLLDTEAIRKDFPILDRQVHDGHKLVYLDNAATSQKPRQV FT LDALSEYYERYNANVHRGVHVLAEEATALYEGARDKVAEFINAPSRDEVIFTKNASESL FT NLVANMLGWADDPYRVDHETEIVITEMEHHSNIVPWQLLAQRTGAKLRWFGLTDDGRLD FT LSNIDEVITEKTKVVSFVLVSNILGTQNPVEAIVRRAQEVGALVCIDASQAAPHMPLDV FT QALQADFVAFTGHKMCGPTGIGVLWGRQELLEDLPPFLGGGEMIETVSMHSSTYAPAPH FT KFEAGTPPVAQAVGLGAAIDYLNSIGMDKILAHEHALTEYAVKRLLEVPDLRIIGPTTA FT EERGAAISFTLGDIHPHDVGQVLDEQGIAVRVGHHCARPVCLRYGIPATTRASFYLYST FT PAEIDALVDGLEHVRNFFG" FT misc_feature complement(234461..235555) FT /note="Pfam match to entry PF00266 aminotran_5, FT Aminotransferases class-V, score 29.60, E-value 8.5e-09." FT CDS complement(235675..236439) FT /transl_table=11 FT /gene="SCO1922" FT /gene_synonym="SCC22.04c" FT /product="putative ABC transporter ATP-binding subunit" FT /note="SCC22.04c, possible ABC transporter ATP-binding FT subunit, len: 254aa; similar to many proposed ABC FT transporter subunit eg. SW:ABCX_CYAPA probable FT ATP-dependent transporter from Cyanophora paradoxa (259 aa) FT fasta scores; opt: 856, z-score: 945.3, E(): 0, (55.3% FT identity in 246 aa overlap). Also highly similar to FT TR:O53154 (EMBL:AL021184) hypothetical protein from FT Mycobacterium tuberculosis (266 aa) fasta scores; opt: FT 1258, z-score: 1383.7, E(): 0, (76.9% identity in 251 aa FT overlap). Contains Pfam match to entry PF00005 ABC_tran, FT ABC transporter and Prosite match to PS00017 FT ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q9XAD4" FT /db_xref="InterPro:IPR010230" FT /db_xref="UniProtKB/TrEMBL:Q9XAD4" FT /protein_id="CAB50747.1" FT /translation="MATLEIRDLHVTVEADNATKEILKGVDLTVKQGETHAIMGPNGSG FT KSTLAYSLAGHPKYTITGGTVTLDGEDVLEMSVDERARAGLFLAMQYPVEVPGVSVSNF FT LRTSATAVRGEAPKLRHWVKEVKEAMERLNMDPAFAERNVNEGFSGGEKKRHEILQLEL FT LKPKVAILDETDSGLDVDALRVVSEGVNRVRETGEVGTLLITHYTRILRYIKPDYVHVF FT ANGRIAESGGAELADKLEAEGYEAYTKGGASE" FT misc_feature complement(235765..236343) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 119.10, E-value 8.4e-32." FT misc_feature complement(236299..236322) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS complement(236447..236764) FT /transl_table=11 FT /gene="SCO1923" FT /gene_synonym="SCC22.05c" FT /product="putative dioxygenase ferredoxin subunit" FT /note="SCC22.05c, possible dioxygenase ferredoxin subunit, FT len: 105 aa; similar to many e.g. SW:BEDB_PSEPU benzene FT dioxygenase from Pseudomonas putida ML2 (107 aa) fasta FT scores; opt: 286, z-score: 390.9, E(): 1.9e-14, (40.6% FT identity in 101 aa overlap)" FT /db_xref="GOA:Q9XAD3" FT /db_xref="HSSP:1FQT" FT /db_xref="InterPro:IPR017941" FT /db_xref="UniProtKB/TrEMBL:Q9XAD3" FT /protein_id="CAB50748.1" FT /translation="MTFVRVCGADELEEDTPKRVELDGTPISVVRTEGELFAIHDICSH FT ANVSLAEGEVDDCHIECWLHGSRFDLRSGKPDSLPATRPVPVYPVKIEGDDVLVSLTQE FT S" FT CDS complement(236761..237945) FT /transl_table=11 FT /gene="SCO1924" FT /gene_synonym="SCC22.06c" FT /product="conserved hypothetical protein" FT /note="SCC22.06c, conserved hypothetical protein, len: FT 394aa; similar to many eg. TR:O53153 (EMBL:AL021184) FT hypothetical protein from Mycobacterium tuberculosis (397 FT aa) fasta scores; opt: 1446, z-score: 1649.9, E(): 0, FT (58.0% identity in 388 aa overlap). Contains Pfam match to FT entry PF01458 UPF0051, Uncharacterized protein family FT (UPF0051)." FT /db_xref="GOA:Q9XAD2" FT /db_xref="InterPro:IPR011542" FT /db_xref="UniProtKB/TrEMBL:Q9XAD2" FT /protein_id="CAB50749.1" FT /translation="MAEAQNIPVGSTTAGQIAVAAESTVATRMSAPASFDVADFPVPHG FT REEEWRFTPLERLRGLHDGTAVATGDGVKVDVEAPEGVVVETVGRDDARIGRAGTPVDR FT VAAQAYSAFEKAGVITVPKETVLTEPIRIAVHGEGGTAYAHQVVELGAFAEAVVVIDHT FT GDAVLAANVDYVLGDGAKLTVVSVQDWDDKAVHVGQHNALVGRDATFKSFVVTFGGDLV FT RLHPRVAYAGPGGEAELFGLYFTDAGQHQEHRLLVDHNVPHCKSNAVYKGALQGDDAHA FT VWIGDVLIEAAAEGTDTYEMNRNLVLTDGARVDSVPNLEIETGEIVGAGHASATGRFDD FT EQLFYLMARGIPELDARRLVVHGFFAELVQQIGVADIEERLLAKIAQELEASVA" FT misc_feature complement(236842..237588) FT /note="Pfam match to entry PF01458 UPF0051, Uncharacterized FT protein family (UPF0051), score 224.10, E-value 2e-63." FT CDS complement(238006..239427) FT /transl_table=11 FT /gene="SCO1925" FT /gene_synonym="SCC22.07c" FT /product="conserved hypothetical protein" FT /note="SCC22.07c, conserved hypothetical protein, len: FT 473aa; similar to many eg. TR:O32162 (EMBL:Z99120) FT hypothetical protein from Bacillus subtilis (465 aa) fasta FT scores; opt: 2087, z-score: 2451.5, E(): 0, (64.6% identity FT in 463 aa overlap). Also similar to the N-terminal region FT and the C-terminal region of TR:O53152 (EMBL:AL021184) FT hypothetical splice protein from Mycobacterium tuberculosis FT (846 aa) fasta scores; opt: 1367, z-score: 1602.5, E(): 0, FT (47.5% identity in 832 aa overlap). Contains Pfam match to FT entry PF01458 UPF0051, Uncharacterized protein family FT (UPF0051)." FT /db_xref="GOA:Q9XAD1" FT /db_xref="InterPro:IPR000825" FT /db_xref="UniProtKB/TrEMBL:Q9XAD1" FT /protein_id="CAB50750.1" FT /translation="MTLPTETAHPELEGLGKYEYGWADSDTAGASAKRGINEDVVRDIS FT AKKNEPEWMTKLRLKGLRLFEKKPMPNWGSDLSGIDFDNIKYFVRSTEKQAESWEDLPE FT DIKNTYDKLGIPEAEKQRLVAGVAAQYESEVVYHQIREDLEEQGVIFLDTDTALKEHPE FT LFKEYFGTVIPVGDNKFASLNSAVWSGGSFIYVPKGVHVEIPLQAYFRINTENMGQFER FT TLIIVDEGAYVHYVEGCTAPIYKSDSLHSAVVEIIVKKNARCRYTTIQNWSNNVYNLVT FT KRAVAYEGATMEWIDGNIGSKVTMKYPAVYLMGEHAKGETLSIAFAGEGQHQDAGSKMV FT HMAPNTSSNIVSKSVARGGGRTSYRGLVEIGEGAHGSKSNVLCDALLVDTISRSDTYPY FT VDVREDDVSMGHEATVSKVSEDQLFYLMSRGLSEFEAMAMIVRGFVEPIAKELPMEYAL FT ELNRLIELQMEGAVG" FT misc_feature complement(238084..238845) FT /note="Pfam match to entry PF01458 UPF0051, Uncharacterized FT protein family (UPF0051), score 494.70, E-value 7.1e-145." FT CDS complement(239424..240182) FT /transl_table=11 FT /gene="SCO1926" FT /gene_synonym="SCC22.08c" FT /product="putative DNA-binding protein" FT /note="SCC22.08c, possible DNA-binding protein, len: 252aa; FT similar to TR:O53151 (EMBL:AL021184) hypothetical protein FT from Mycobacterium tuberculosis (278 aa) fasta scores; opt: FT 629, z-score: 705.6, E(): 5.8e-32, (46.8% identity in 233 FT aa overlap). Contains a helix-turn-helix motif (+4.75 SD) FT at residues 34-55" FT /db_xref="GOA:Q9XAD0" FT /db_xref="InterPro:IPR001845" FT /db_xref="UniProtKB/TrEMBL:Q9XAD0" FT /protein_id="CAB50751.1" FT /translation="MKNVGEAPQEELATGERSTRNRVARSILDHGPSTVAELAGRLGLT FT QAAVRRHLDALVADDVVEPREQRVYGARTRGRPAKVFALTDCGRDAFDQSYDKLAADAL FT RWIAEQEGGEQAIAAFARARIAAQSGAYRAAVESVPAEKRAEALAKALSEDGYAATARS FT APHPQQGEQLCQHHCPVAHVAEQFPQLCEAETEFFAELLGTHVQRLATIAHGDGVCTTF FT IPKTSHAPPPARASENTANASASTAGRNPA" FT CDS 240354..241142 FT /transl_table=11 FT /gene="SCO1927" FT /gene_synonym="SCC22.09" FT /product="putative aminoglycoside acetyltransferase" FT /note="SCC22.09, possible aminoglycoside acetyltransferase, FT len: 262 aa; similar to many e.g. SW:AAC8_STRFR FT aminoglycoside acetyltransferase from Streptomyces fradiae FT (286 aa) fasta scores; opt: 502, z-score: 576.5, E(): FT 8.9e-25, (40.4% identity in 270 aa overlap)" FT /db_xref="GOA:Q9XAC9" FT /db_xref="InterPro:IPR003679" FT /db_xref="UniProtKB/TrEMBL:Q9XAC9" FT /protein_id="CAB50752.1" FT /translation="MSTPPPTGPLVTRGTLAAGLRELGVRTGDTLLAHSSLSALGWVCG FT GPVAVVRALLDVLGPDGTLVVPTQTGDLSDPALWTSPPVPEEWWETVRAATPAYDPLIT FT PSRGVGVVPETVRTWPGARRSAHPQTSFAALGGRAAEVVAGHATDCRLGERSPLAALER FT LDARVLLLGAGYDACTAFHLAEYRIPAPLVEVGRPGPVGWERVTEVSITSERFDELGHD FT FERDRPVARGRVGAADVRLFSLPDAVAYAERWLPVHRPRE" FT CDS 241219..242142 FT /transl_table=11 FT /gene="SCO1928" FT /gene_synonym="SCC22.10" FT /product="putative ABC transporter, ATP-binding subunit" FT /note="SCC22.10, possible ABC transporter, ATP-binding FT subunit, len: 307aa; similar to many egs. SW:DRRA_STRPE FT daunorubicin resistance ATP-binding protein from FT Streptomyces peucetius (330 aa) fasta scores; opt: 571, FT z-score: 637.1, E(): 3.7e-28, (35.6% identity in 315 aa FT overlap) and TR:O53149 (EMBL:AL021184) putative ABC FT transporter, ATP-binding protein from Mycobacterium FT tuberculosis (313 aa) fasta scores; opt: 1170, z-score: FT 1297.6, E(): 0, (60.9% identity in 304 aa overlap). FT Contains Pfam match to entry PF00005 ABC_tran, ABC FT transporter and Prosite matches to PS00017 ATP/GTP-binding FT site motif A (P-loop) and PS00211 ABC transporters family FT signature." FT /db_xref="GOA:Q9XAC8" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9XAC8" FT /protein_id="CAB50753.1" FT /translation="MRSEPVVQVQALVKRYGTKTAVNGLDLVARTGVTAVLGPNGAGKT FT TTVETCEGYRRPDSGTVRVLGLDPVRQGAELRPRIGVMLQSGGVYSGARADEMLRHVAK FT LHAHPLDVDALIERLGLDSCGRTTYRRLSGGQQQRLALAMAVVGRPELVFLDEPTAGLD FT PQARRATWDLVRDLRGDGVSVILTTHHMDEAEQLADDVAIIDTGRVVAQGSPEELCRGG FT AENTLRFTGRPGLDVASLLKALPPDSAAAELTPGSYRVNGEVDPQLLATVTSWCAQHGV FT MPDRISVERHTLEDVFLELTGKELRG" FT misc_feature 241309..241839 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 154.80, E-value 1.4e-42." FT misc_feature 241330..241353 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 241612..241656 FT /note="PS00211 ABC transporters family signature." FT CDS 242139..242948 FT /transl_table=11 FT /gene="SCO1929" FT /gene_synonym="SCC22.11" FT /product="putative integral membrane transport protein" FT /note="SCC22.11, possible integral membrane transport FT protein, len: 269aa; function predicted as it contains FT possible membrane spanning hydrophobic regions and is FT located alongside a possible ABC transport ATP-binding FT protein (SCC22.10). Similar to egs. TR:O86349 FT (EMBL:AL021184) hypothetical protein from Mycobacterium FT tuberculosis (261 aa) fasta scores; opt: 627, z-score: FT 670.8, E(): 4.9e-30, (43.6% identity in 264 aa overlap) and FT TR:AAD20380 (EMBL:AF125999) daunorubicin resistance protei FT n C from Mycobacterium avium (263 aa) fasta scores; opt: FT 266, z-score: 291.2, E(): 7e-09, (29.6% identity in 247 aa FT overlap)." FT /db_xref="GOA:Q9XAC7" FT /db_xref="InterPro:IPR013525" FT /db_xref="UniProtKB/TrEMBL:Q9XAC7" FT /protein_id="CAB50754.1" FT /translation="MTTTTGTPGNTGTPGAAGTYAPRPGAAPLGRMIAAQAVLETKMLL FT RNGEQLLLTVIIPTLLLVLFSSVDIIDTGAGEAVDFLAPGILALAVMSTAFTGQAIATG FT FERRYGVLKRLAASPLPRWALMTAKTASVLVTEVLQIVLLTVIALALGWSPHGNPAAVL FT LLLVLGTAAFSGLGLLMAGTLKAEATLAAANLVFLLLLVGGGVIVPLDRFPDAAQDVLG FT LLPISALSDGLRDVLQHGAAMPWGDLGILAGWAVAGLAAAGKFFRWE" FT CDS 242955..244025 FT /transl_table=11 FT /gene="SCO1930" FT /gene_synonym="SCC22.12" FT /product="putative integral membrane transport protein" FT /note="SCC22.12, possible integral membrane transport FT protein, len: 356aa; function predicted as it contains FT possible membrane spanning hydrophobic regions and is FT located alongside a possible ABC transport ATP-binding FT protein (SCC22.10). Similar to TR:O53148 (EMBL:AL021184) FT hypothetical protein from Mycobacterium tuberculosis (310 FT aa) fasta scores; opt: 527, z-score: 648.1, E(): 9.2e-29, FT (35.0% identity in 300 aa overlap)." FT /db_xref="GOA:Q9XAC6" FT /db_xref="InterPro:IPR003780" FT /db_xref="UniProtKB/TrEMBL:Q9XAC6" FT /protein_id="CAB50755.1" FT /translation="MPRTDPRESVHKRAPTMDGVPNVTRADAVAAVRNPLAFIAARWTP FT HPRTVQRAALAPIVMSVIIVVTGGAVRLTGSGLGCPTWPKCTDDSLTTTSEMGFHGIIE FT FGNRMLTYVLCAAVGWAIIAARSQKPYRRSLTLLGWAQFWVVMSNAVLGGIVVLVGLNP FT YTVAAHFVATTALLTLATLMWQRTREGDTAPRPLVGKSVQQLVWVMVVVSALLVVVGTV FT VTGAGPHAGDSSDVPRMPVDWEMISKAHAVLAWIVVTLTFALWFVLKAVDAPKGPLART FT RDLFLVLLAQGAIGYVQYFTDLPEVLVGLHMFGSCLVWIAVLRVLLALRERPEETVPGL FT PSQEYDATSVSMAGPR" FT CDS complement(243980..244759) FT /transl_table=11 FT /gene="SCO1931" FT /gene_synonym="SCC22.13c" FT /product="hypothetical protein" FT /note="SCC22.13c, unknown, len: 259aa;" FT /db_xref="GOA:Q9XAC5" FT /db_xref="InterPro:IPR002934" FT /db_xref="UniProtKB/TrEMBL:Q9XAC5" FT /protein_id="CAB50756.1" FT /translation="MYTPEGVVDTGRMPTDALLDRFLTGLTPLDPVAVWAHGSLGAGDY FT QEGRSDLDLIAVLPRPATARTAWRLGLLHARLRAEPLAGLLHCTYLSPDTVADPDQRHL FT TWAHQQLFKRTVTPVTRRELHSFGRVLHGESPEQLLPPVPDRELHAFVVRDQREFWRPH FT VHRAELWSQDVWVDLGLITFARATVTLREGRLITKRQALDELPALGAPGEVVEDITERR FT YGNRARPAVTGEWTARRAELTRGYLGPAIDTLVASYS" FT CDS complement(244763..245869) FT /transl_table=11 FT /gene="SCO1932" FT /gene_synonym="SCC22.14c" FT /product="conserved hypothetical protein" FT /note="SCC22.14c, unknown, len: 368aa; similar to TR:O07751 FT (EMBL:Z97193) hypothetical protein from Mycobacterium FT tuberculosis (378 aa) fasta scores; opt: 772, z-score: FT 899.4, E(): 0, (40.3% identity in 372 aa overlap)." FT /db_xref="GOA:Q9XAC4" FT /db_xref="InterPro:IPR006992" FT /db_xref="UniProtKB/TrEMBL:Q9XAC4" FT /protein_id="CAB50757.1" FT /translation="MIETPSLVDQYCHGVLRTELGLGTFEAQLARTEGPPAPGTTLFDT FT QTGFAVRRWCPPLLGLEPHCPPARYLARRRELGVMEADRRLLRGSGITTYLVDAGLPGD FT LTGPTEMATAADADTREIVRLELLAEQVADTSGTVESFLANLAEAVHGAAVNAVAFTSV FT AGVRHGLALAPEPPGPGEVRGAAARWLTGREVGGELSDPVLLRHLLWIAVASGLPLQLH FT AGLGEPGLRIDRTDPVLLTDFVRTTAGLGTDLVLLHGYPYHRHAAHLAGVFPHVYADSG FT AALVRTGARAATVLAEILELAPFGKILFSSGAQGLPELHVVAARLFREALGRVLGTWVA FT EGAWSPGDAQRVAAMIASGNAARVYGLE" FT CDS complement(245984..246418) FT /transl_table=11 FT /gene="SCO1933" FT /gene_synonym="SCC22.15c" FT /product="hypothetical protein" FT /note="SCC22.15c, unknown, len: 144aa;" FT /db_xref="UniProtKB/TrEMBL:Q9XAC3" FT /protein_id="CAB50758.1" FT /translation="MRGQGHAPRPSPFDLPVGSILLMADTQQVDTEQSGAKGGWAGRWD FT AYEVTRTAGRIEAFAKAHGGAEAQVAHLGERGARIVLVGADGAWGDLVARTHERARKAV FT EKSGITVHEDFDGEFAAKVTTGRYEWSRMAGIQVGGPSNT" FT CDS complement(246439..247461) FT /transl_table=11 FT /gene="SCO1934" FT /gene_synonym="SCC22.16c" FT /product="putative cytochrome oxidase assembly factor" FT /note="SCC22.16c, possible cytochrome oxidase assembly FT factor, len: 340 aa; similar to many e.g. TR:O33143 FT (EMBL:Z99125) cytochrome C oxidase assembly factor from FT Mycobacterium leprae (289 aa) fasta scores; opt: 925, FT z-score: 1077.3, E(): 0, (49.3% identity in 286 aa overlap) FT and SW:CYOE_ECOLI cytochrome O ubiquinol oxidase operon FT protein, CyoE from Escherichia coli (296 aa) fasta scores; FT opt: 520, z-score: 609.0, E(): 1.4e-26, (32.7% identity in FT 284 aa overlap). Contains Pfam match to entry PF01040 FT COX10_ctaB_cyoE, Cytochrome c oxidase assembly factor, FT Prosite match to PS00943 Cytochrome c oxidase assembly FT factor COX10/ctaB/cyoE signature and possible membrane FT spanning hydrophobic regions." FT /db_xref="GOA:Q9XAC2" FT /db_xref="InterPro:IPR000537" FT /db_xref="UniProtKB/Swiss-Prot:Q9XAC2" FT /protein_id="CAB50759.1" FT /translation="MAWYARAFTATSHGRACWESLSGVCVTAVESRPAGVIGTSQSPSH FT RPFGARVKAFVALTKPRIIELLLITTVPVMFLAEQGVPNLKLVLLTCVGGYLSAGGANA FT LNMYIDRDIDALMDRTSQRPLVTGMVSPVECLVFGITLAIVSTLLFGFTVNWLSAWLSL FT GALLFYVVVYTMILKRRTSQNIVWGGIAGCLPVLIGWSAVTNSMSWAPVILFGVMFFWT FT PPHYWPLSMKVKEDYARVGVPMLPVIASNKVVARQIVIYSWVMVVVSLLLQPLGYTGWF FT YTAVALAAGGMWLWEAHGLQNRAKAEVTGGKLKEMRLFHWSITYVSVLFLAIAVDPFLR FT " FT misc_feature complement(246448..247272) FT /note="Pfam match to entry PF01040 COX10_ctaB_cyoE, FT Cytochrome c oxidase assembly factor, score 326.00, E-value FT 4.3e-94." FT misc_feature complement(247078..247128) FT /note="PS00943 Cytochrome c oxidase assembly factor FT COX10/ctaB/cyoE signature, [ED].D.{2}M.RT.{2}R.{4}G, info FT count = 28.9." FT CDS 247763..249850 FT /transl_table=11 FT /gene="SCO1935" FT /gene_synonym="SCC22.17" FT /gene_synonym="tktA1" FT /product="transketolase A" FT /note="SCC22.17, tktA1, probable transketolase, len: 695aa; FT similar to many egs. TR:O88019 (EMBL:AL031107) tkt, FT transketolase from Streptomyces coelicolor (698 aa) fasta FT scores; opt: 3653, z-score: 4066.7, E(): 0, (79.1% identity FT in 685 aa overlap) and TR:CAB19861 (EMBL:AB023377) FT glutamicum |