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EBI DbfetchID AL939105; SV 1; linear; genomic DNA; STD; PRO; 291000 BP. XX AC AL939105; AL109974; AL117385; AL117387; AL117669; AL121596; AL121600; AC AL121719; AL121849; AL121855; AL132662; AL132707; XX DT 25-OCT-2002 (Rel. 73, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 5) XX DE Streptomyces coelicolor A3(2) complete genome; segment 2/29 XX KW . XX OS Streptomyces coelicolor OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Streptomycineae; Streptomycetaceae; Streptomyces. XX RN [1] RP 1-291000 RA Bentley S.D.; RT ; RL Submitted (09-MAY-2002) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Streptomyces sequencing team, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL sdb@sanger.ac.uk XX RN [2] RX DOI; 10.1038/417141a RX PUBMED; 12000953. RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L., RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H., RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E., RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D., RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.; RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor RT A3(2)"; RL Nature 417(6885):141-147(2002). XX DR EMBL-CON; AL645882. XX FH Key Location/Qualifiers FH FT source 1..291000 FT /organism="Streptomyces coelicolor" FT /strain="A3(2)" FT /mol_type="genomic DNA" FT /db_xref="taxon:1902" FT CDS 213..3092 FT /transl_table=11 FT /gene="SCO0305" FT /gene_synonym="SC5G9.14" FT /product="conserved hypothetical protein" FT /note="SC5G9.14, hypothetical protein, len: 959 aa; unknown FT function, similar to TR:O54182 (EMBL:AL021411) Streptomyces FT coelicolor hypothetical protein (913 aa), fasta scores; FT opt: 698 z-score: 776.6 E(): 0, 27.0% identity in 972 aa FT overlap. The C-terminus shows very weak similarity to FT eukaryotic beta-transducins e.g. SW:GBB4_MOUSE FT (EMBL:S86124), gnb4, Mus musculus guanine FT nucleotide-binding protein beta subunit 4 (340 aa) (23.0% FT identity in 291 aa overlap). Contains possible hydrophobic FT membrane spanning region" FT /db_xref="GOA:Q9RL12" FT /db_xref="InterPro:IPR015943" FT /db_xref="UniProtKB/TrEMBL:Q9RL12" FT /protein_id="CAB55662.1" FT /translation="MSDAVEEAEARAVEPVGAKQRDAFISYSQSKNAPLAKQLQRGLER FT LAVSRFRPMRMSVFRDVTSLPANHDLWQSIQRELARSRYFILLASPEAAASPWVAREVD FT YWLRERDTEHLLIAVASGEIVWDDRAGDFDWRKTTSLPRNLAGHFTAAPLWVDLREIGE FT RSHHSMRYPPFRAAVATLASPLHGRPKEELEHDDFRQLRFVKRLSWSGVALLVALLVLA FT VYGFFDASRQREAALSQARTSASQALAARSGQLLGTSPNQAAQYALYAEETRSTPESRR FT ALAQAVTAAPYARRRLRADADSVTDMQGASRPAATDVVLSGDGTTAAYRSVFDDDRAVR FT LYDVPSARQSRVVRAEGTPRALSRDGRVLAMEVYLNRVQLWDTRSGRLLSTMATGHTEN FT LPHVGHGLHALALSPDGRWVAASHYTPEGEAFAVVWRASDGREITRVPVSDARVGLGFS FT ADGSRLTLVDQDRREVREFRTDSARWEAARSLPGMPGSTAEALRYSEVLLFDGARKALT FT RTSERAEVWDLEQRRRIAVRSLGPYEDMTVADDKGIFLLGGQDGTVRLYDAALRPGTTL FT GRLTRPASTIAMSADGTQVVVASYGGELNLFTTGVRRGQQVAFDEKDFTFGDLTPDGRM FT AVHRSEGRTEFWDPATGRRLGVIPYANLSVNLEDTAYTLSGDKRYVGMQSVEGFEDEGR FT FDVWDLRTGRRTDCGTAVGGSSFSPIRRPGLSFLPGDRYVVGEWNGAVELLDTRTCTRS FT TVTEDSGRFALSGDRRTLVLLNDDGVDTWRWDGDHAFARAARTTLPSEAHPVDMSVDHE FT GRQAAFSDRESHVYVVRLDSGERVRATGYLPDKTDAVAFSRDGRLLFQGFMTESTRGVR FT VLDAGSGDQLDIWTTDPPTGSVQPNEGMQVVPGPADDILTLGPDHKVVRRTVGVGAWHD FT LLCGLVSQPLPARERDRYLKDLDVEDPCR" FT CDS complement(3056..3961) FT /pseudo FT /transl_table=11 FT /gene="SCO0306" FT /gene_synonym="SC5G9.15c" FT /product="putative pseudogene" FT /note="SC5G9.15c, possible pseudogene, len: 302 aa; similar FT to hypothetical proteins e.g. SW:YCJY_ECOLI FT (EMBL:AE000230), YcjY, Escherichia coli hypothetical FT protein (310 aa). GC frameplot and codon usage plots FT indicate a coding region which lacks a start codon" FT CDS 4084..4971 FT /transl_table=11 FT /gene="SCO0307" FT /gene_synonym="SC5G9.16" FT /product="putative DNA-binding protein" FT /note="SC5G9.16, possible DNA-binding protein, len: 295 aa; FT probable CDS suggested by GC frameplot and positional base FT preference. Similar to possible DNA-binding proteins from FT S. coelicolor e.g. SCJ9A.15c (cosmid SCJ9A), S. coelicolor FT possible DNA-binding protein (290 aa) (39.3% identity in FT 298 aa overlap). Contains probable helix-turn-helix motif FT at residues 35-56 (Score 1197, +3.26 SD)" FT /db_xref="GOA:Q9RL11" FT /db_xref="InterPro:IPR016160" FT /db_xref="UniProtKB/TrEMBL:Q9RL11" FT /protein_id="CAB55664.1" FT /translation="MSSELGDFLKARRRELSPPTAGLPADGRRRVPGLRREEVAVLASI FT SPGHYTRLEQGRRRASEPVLDALARALRLSADERAYLFELSGKDAGRPLGRPGRQVRPQ FT LRRLLDDLTHTPALVLGRCTDILAWNPPAAALFTDFALLSRDERNFVRLVFRDPAVRAL FT YTDWPYMARACVAQLRMEAARDPHDPRLSALVAELSAQDPDFRTWWKDHRVAVRGAGTK FT DLRHPVIGELTLDWSALTDTADPDQQLIALTAAPGTPSHDGLRALRDLGAVTSGRTGPG FT VPGGGGEIAGASAQ" FT CDS 5026..6429 FT /transl_table=11 FT /gene="SCO0308" FT /gene_synonym="SC5G9.17" FT /product="putative membrane protein" FT /note="SC5G9.17, possible membrane protein, len: 467 aa; FT unknown function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Contains hydrophobic, possible membrane-spanning regions FT near the C-terminus. Contains TTA (leucine) codon; possible FT target for bldA regulation" FT /db_xref="UniProtKB/TrEMBL:Q9RL10" FT /protein_id="CAB55665.1" FT /translation="MPRSDAAVRVRTRLLLMYHLTPQVHVPDDRLRPLSEALGLGRFTA FT HVEAAGLLLPRLVLHERVREITLPPNAARVDGADITLAVTPRQDPLLFVDVEVPDEAGD FT SDTIAETLYATWQDRSAIRVGGVPLTAWLDERLRAYGLTDRTADRPPLAFGRNVHQSVF FT PGAALAGRLLAAHVPGDAVGQDVVTIVLRGTLDSGTGATLGIRRPETLNNAGQTMVAHG FT RGVSLIVGYAPPVENAFGLAAAGILTAVAAVHRIRRQAFAALELDRAAAVETTDAARAL FT VAQLSHRLNDLQLDLSFSVEVYADTILVPELLVESFHASLRDVSSLADALANTSRIVER FT VNAVLATRRVGLETAAQQYAEDRDRVLAAVIAAGSLLALPPALLLAYFGVNSSDVDPSR FT SILDFQHYGVAYAIAWSPFLLLILVGLLARRRISLRLPAPDAATSERRTRRFRRSLRSW FT LGRSRRPGR" FT misc_feature 5434..5436 FT /note="TTA (leucine) codon; possible target for bldA FT regulation" FT CDS complement(6537..7625) FT /transl_table=11 FT /gene="SCO0309" FT /gene_synonym="SC5G9.18c" FT /product="putative amide hydrolase" FT /note="SC5G9.18c, probable amide hydrolase, len: 362 aa; FT similar to 6-aminohexanoate-dimer hydrolases which degrade FT N-(6-aminohexanoyl)-6-aminohexanoate e.g. TR:P75007 FT (EMBL:K02336), NylB', Flavobacterium sp. (strain K172) FT 6-aminohexanoic acid linear oligomer hydrolase (EII') (392 FT aa), fasta scores; opt: 531 z-score: 598.0 E(): 6.1e-26, FT 34.1% identity in 323 aa overlap" FT /db_xref="GOA:Q9RL09" FT /db_xref="InterPro:IPR001466" FT /db_xref="UniProtKB/TrEMBL:Q9RL09" FT /protein_id="CAB55666.1" FT /translation="MPSRRVWRGRGGPGDLPASPPGALDGLGVTGSYGRTLTLDQLLAE FT AETDALLVLHRGRLVHEEYRHGYEAHVPHFNASAAKSYLGLLAATLAHEGHLDRGARVA FT RYVPELSGTAFGDAQVDHLMHMGTRMSYAGRPYDKALEAQRYFAVLAPRLRPYGYSGPA FT TIREHLATARATGEPGTEFRYENGNVEALAEVLRRITGLSTSALMSEMIWSRIGAEEDA FT YYLVDADGAEAACGGFSATARDVARLGELVRCGGAVGDRQVLPEAVTAPARSVPDGCPR FT RVRFPAAPADSPATLSYHDLWWILNDPYGSFMASGIHGQRLFVSPALDLVVVHYASQVV FT SPAVPQVPLVQAFLSIGAHLNA" FT CDS complement(7816..8466) FT /transl_table=11 FT /gene="SCO0310" FT /gene_synonym="SC5G9.19c" FT /product="putative tetR-family transcriptional regulator" FT /note="SC5G9.19c, possible tetR-family transcriptional FT regulator, len: 141 aa; shows similarity to the N-terminal FT half of TR:O24741 (EMBL:AB001683), FarA, Streptomyces sp. FT strain FRI-5 receptor for an extracellular regulatory FT factor (IM-2) (221 aa), fasta scores; opt: 154 z-score: FT 193.4 E(): 0.0021, 36.7% identity in 79 aa overlap and to FT putative transcriptional regulators. Contains Pfam match to FT entry PF00440 tetR, Bacterial regulatory proteins, tetR FT family" FT /db_xref="GOA:Q9RL08" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9RL08" FT /protein_id="CAB55667.1" FT /translation="MDMKPEDRRVRRTRAALRKALVELVLDKGFQAVTVEEITERADIG FT RATFYAHYRDKEDLLVGIVRDLAQDRERLLPAVRQAHAQGFTGLPVKYIFEHAAQERGV FT YQVILRGEGDGRALREFTELIRSHAEMAFRDRARQLGVEPRIPLGIVARAWTGELISVL FT GWWVENDTGYTAEQITAHLRDLSVYGRVWATGLTPVDAPGAVDLPGGRGAEPV" FT misc_feature complement(8278..8418) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 31.50, E-value FT 5.4e-07" FT CDS 8575..10131 FT /transl_table=11 FT /gene="SCO0311" FT /gene_synonym="SC5G9.20" FT /product="putative ligase" FT /note="SC5G9.20, probable ligase, len: 518 aa; similar to FT domains within polyketide synthases e.g. to the N-terminus FT of TR:Q54297 (EMBL:X86780), RapA, Streptomyces FT hygroscopicus polyketide synthase (8563 aa), fasta scores; FT opt: 815 z-score: 894.4 E(): 0, 34.0% identity in 509 aa FT overlap and to SW:DHBE_BACSU (EMBL:U26444), DhbE, EntE, FT Bacillus subtilis 2,3-dihydroxybenzoate-AMP ligase (539 aa) FT (31.3% identity in 520 aa overlap). Also similar to others FT from S. coelicolor e.g. TR:Q9Z5A6 (EMBL:AL035478) S. FT coelicolor probable long-chain-fatty-acid-CoA ligase (541 FT aa) (35.9% identity in 537 aa overlap). Contains Pfam match FT to entry PF00501 AMP-binding, AMP-binding enzyme and FT PS00455 Putative AMP-binding domain signature" FT /db_xref="GOA:Q9RL07" FT /db_xref="HSSP:1LCI" FT /db_xref="InterPro:IPR000873" FT /db_xref="UniProtKB/TrEMBL:Q9RL07" FT /protein_id="CAB55668.1" FT /translation="MNLGRYVRRTAEHHPDAEAVVCGHVRLTYAELDDHSDRLAAALTG FT LGLSRGERVATLAANRAELVVTEVALYKAGLTRAPVNARLGDGEVAHLLRESDARVLLT FT DAAHLDTARRAVPGSGVKAVIGYDGPADLGPGYQELLAATPREAVDVECAEDDIAVLHF FT TSGSTGKLKAAVQTYGNRLALLRKSVMNQATRVGTGDRQILAGPVTHASGMPLMGIFFA FT GGCAVVLPRWDAAEFLATVERERATHAFLVPTMVNTVLALENARDHDLSSLRHLLYGAA FT PMSPARVRAAWDLFGPVLSQGYGCGETTSGVLFLSTEDHRRAVEGDDEELLLSCGRPLA FT EAEVRIVDDGGEPVADGEIGEIAVRGPDVVPGYHNEPELTARSFRDGWFLTGDLARRRR FT DGYVFIVDRKKDMIISGGFNIYAVEVESVLHQHPDVFEAAVVGVPDEQWGEAVKAVVVP FT RAGVTLDATELIAFCAEHLARMKKPRSVDVVAALPHNPNGKIDRRAIRDTYWSGAERRV FT H" FT misc_feature 8656..9894 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 140.40, E-value 3.1e-38" FT misc_feature 9055..9090 FT /note="PS00455 Putative AMP-binding domain signature" FT CDS 10147..11316 FT /transl_table=11 FT /gene="SCO0312" FT /gene_synonym="SC5G9.21" FT /product="putative acyl-CoA dehydrogenase" FT /note="SC5G9.21, probable acyl-CoA dehydrogenase, len: 389 FT aa; similar to both bacterial and eukaryotic acyl-CoA FT dehydrogenases e.g. SW:ACDS_HUMAN (EMBL:M26393), AcaDS, FT Homo sapiens mitochondrial acyl-CoA dehydrogenase FT short-chain specific precursor (412 aa), fasta scores; opt: FT 653 z-score: 771.4 E(): 0, 34.8% identity in 376 aa FT overlap. Also similar to SCI30A.22C (EMBL:AL096811) FT Streptomyces coelicolor probable acyl-CoA dehydrogenase. FT Contains 2 Pfam matches to entry PF00441 Acyl-CoA_dh, FT Acyl-CoA dehydrogenase" FT /db_xref="GOA:Q9RL06" FT /db_xref="HSSP:1JQI" FT /db_xref="InterPro:IPR006092" FT /db_xref="UniProtKB/TrEMBL:Q9RL06" FT /protein_id="CAB55669.1" FT /translation="MPFTLTPRYDDNPRLEELVGRLRAYLTDELLPYERAHGITPESKL FT DRATLESVWKRSAELGFYGISLPPELGGQGLSFTELCALKEELTSSGAALSHSVLGDMG FT GPLRVGAIVKYATDEQRERYLLPVVRGERACCFSLTEQDAGSDVRRMRTTATPDGDSYV FT LNGHKVFSSAAPFADFAVVVARMADSEETYSAFLVDLDTPGCRVLDGAVPMSGQQMEGD FT LVFEDCRVPVANLLGEIGQGLRIGIGRITLNRLLHCPSLIGAARRAWDLSVDHAKTRVA FT FGQPLLALQAIQHKLADMATDLYAARSMVQATAAKADRGENIAVEANMCKLFTAEACFR FT TADQAVQIHGKDGLTRGHEVEQIFRSLRMFRIVTGTTEIHKNAIVKALV" FT misc_feature 10294..10758 FT /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA FT dehydrogenase, score 109.50, E-value 2.6e-31" FT misc_feature 10813..11304 FT /note="Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA FT dehydrogenase, score 155.40, E-value 9.4e-45" FT RBS 11367..11371 FT /note="possible RBS" FT CDS 11378..12727 FT /transl_table=11 FT /gene="SCO0313" FT /gene_synonym="SC5G9.22" FT /product="putative transmembrane transport protein" FT /note="SC5G9.22, probable transmembrane transport protein, FT len: 449 aa; similar to many transmembrane transporters FT e.g. SW:DGOT_ECOLI (EMBL:L10328), dgoT, Escherichia coli FT D-galactonate transporter (445 aa), fasta scores; opt: 332 FT z-score: 376.2 E(): 1.4e-13, 23.7% identity in 438 aa FT overlap. Contains hydrophobic, possible membrane-spanning FT regions. Contains Pfam match to entry PF00083 sugar_tr, FT Sugar (and other) transporter" FT /db_xref="GOA:Q9RL05" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9RL05" FT /protein_id="CAB55670.1" FT /translation="MAARSSAPPADRSARRPAVRPYDRRRAWLVTAMIVTFMVINFADK FT SVLGLAAVPIMDELNISNSTYGLISSSFYLFFSLSGLVVGFFASRISSRTMLFVMALLW FT AVAQLPVLAVAAVPTLIAGRVLLGVAEGPAASMSMHALYKWFPPERRGLPSALQIGGAA FT IGTLVSAPVLTWLITDFGWRSAYAVLAVVSLLWALVWRQTGHDGPFDESRPPRADAPRP FT GTHLPYRRLLLTGTVLGSIASAFGAAWALALAHAWLPAYLRTQLDMSPHAVATAISAIS FT ALSLVLLLTVSPLVDALKARGVSSRWSSGAVQGASVCVAGCAMAAFPFTDGAVVRLLLI FT AVAFGTVAVAIPLHYVTAAEVVPGARRGAVFGIVAATGTLPGLIAPFVTGRLIDTADTA FT SSGYTTAFLIAAAVMLLAGTAAVIAIRPEHDARRLGLLHPTTDPEKGAHT" FT misc_feature 11462..12700 FT /note="Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter, score -70.60, E-value 0.00025" FT CDS 12724..14670 FT /transl_table=11 FT /gene="SCO0314" FT /gene_synonym="SC5G9.23" FT /product="putative secreted protein" FT /note="SC5G9.23, putative secreted protein, len: 648 aa; FT unknown function, similar to TR:Q52556 (EMBL:M86744), SdsA, FT Pseudomonas sp. alkyl sulfatase which degrades sulfate FT esters of long-chain primary alcohols (SDS) (528 aa), fasta FT scores; opt: 739 z-score: 806.7 E(): 0, 29.7% identity in FT 528 aa overlap, but having an N-terminal extension of FT approx. 140 aa. Similar to TR:Q48790 (EMBL:X92423), SepA, FT Listeria monocytogenes gene implicated in cell separation FT (391 aa) (42.6% identity in 364 aa overlap). Also similar FT to hypothetical proteins e.g. TR:O69728 (EMBL:AL022121) FT Mycobacterium tuberculosis hypothetical protein (626 aa) FT (52.9% identity in 624 aa overlap). Contains Pfam match to FT entry PF00753 lactamase_B, Metallo-beta-lactamase FT superfamily. Contains possible N-terminal region signal FT sequence peptide" FT /db_xref="GOA:Q9RL04" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q9RL04" FT /protein_id="CAB55671.1" FT /translation="MNPMNRRGFVAAAAGAAAATVPLSAQAAEASPGRGPSGTPTPTHT FT GDLPYDDRTDFADADRGFVAAYTGGLITTPSGGTAWDPDAYRFLTDAAETAPTTVDPSL FT WRQARLLSRQGLYEVTHRIYQVRGLDLANMTVVEGDTGIIVIDPLTSAETAAAALRLYR FT AHRGNRPVRALIYTHPHVDHFGGCRGVLPDGTEDVPVLAPRGFMEHAVSENVYAGPAMS FT RRAGYMYGTNLPTDAAGQVGCGLGLAVSTGTIGLIPPTRYIETTGQEATLDGVRFRFQM FT TPGTECQEEMNVLLPDLRAVCMAENATHTMHNILTLRGAQVRDAHAWAGYLTESIGLCT FT GTADVAFASHHWPTWGNDDIVALLTRQRDLYGYLHDQTVRLINKGLNGTEIAESLRLPP FT QLEQVWANRGYYGSLSHNVKAVYQRYMGWFDANPAHLWEHPPAEEARRWVESLGGQAAV FT RARARHYSERGDLRFAVTLLNHAVFNDPSDTRAKQQLATLYIRLGRAAENAVWRNFFLT FT GAQELVHGAEPAPKPTSGPDLHRALTVGQLIDGLAVRVNGPDAWSLRLALDWHIGDTYW FT HLRLANGVLTWTSDASPDPDAGLTMTMTRAQLLAVLAGKGTDGVTMTGDGTQLVRLLSV FT LDTADHRFPVVTP" FT misc_feature 13090..13773 FT /note="Pfam match to entry PF00753 lactamase_B, FT Metallo-beta-lactamase superfamily, score 69.40, E-value FT 7.3e-17" FT CDS complement(14697..16055) FT /transl_table=11 FT /gene="SCO0315" FT /gene_synonym="SC5G9.24c" FT /product="putative decarboxylase" FT /note="SC5G9.24c, probable decarboxylase, len: 452 aa; FT similar to many e.g. SW:DCDA_BACSU (EMBL:L09228), LysA, FT Bacillus subtilis diaminopimelate decarboxylase (441 aa), FT fasta scores; opt: 484 z-score: 542.1 E(): 7.9e-23, 31.6% FT identity in 389 aa overlap. Similar to TR:Q9ZBH5 FT (EMBL:AL035206), DcdA, Streptomyces coelicolor FT diaminopimelate decarboxylase (440 aa), fasta scores; opt: FT 400 z-score: 384.5 E(): 3.6e-16, 30.2% identity in 427 aa FT overlap. Contains 2 Pfam matches to entry PF00278 FT Orn_DAP_Arg_deC, Pyridoxal-dependent decarboxylase, PS00879 FT Orn/DAP/Arg decarboxylases family 2 signature 2 and PS00878 FT Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment FT site" FT /db_xref="GOA:Q9RL03" FT /db_xref="InterPro:IPR002986" FT /db_xref="UniProtKB/TrEMBL:Q9RL03" FT /protein_id="CAB55672.1" FT /translation="MTSGSLHQRGTAREAALARAVEDGLLGPRTPLVGLLDVDGVLAAV FT DALNEAFEGPAPVQHTFAAKACGLVPVLRLLAEAGMGCEVASPGELEQALAAGFTYDRL FT VFDSPAKTVEELEFALAHGIAINLDNFQEMARVDGLLAGREAAGPIGLRVNPQVGAGAI FT GAMSTATATSKFGVALRDEGAVDAVIEAFARRPWLNRLHAHVGSQGCPLPLIAQGVRTA FT YELAERINRELGRAQITGLDIGGGLPVNFDGEDDRPTYADHVAELRSAAPGLFDGRYAL FT ITEFGRSLLAKSGTIASVVEYTKSAGGRRIAVTHAGAQVATRTVFMPDAWPLRVGVFDA FT AGRPKQGPAEVVDIAGPCCFAGDLTATGRELPAVEPGDVVALYDTGAYYFSSHFSYNSL FT PRPAVYGYRTDSRGQIAFALVREAQSVRAVVEESGLAQADALVALGTDQSAER" FT misc_feature complement(14859..15020) FT /note="Pfam match to entry PF00278 Orn_DAP_Arg_deC, FT Pyridoxal-dependent decarboxylase, score 28.10, E-value FT 1.2e-07" FT misc_feature complement(15105..15905) FT /note="Pfam match to entry PF00278 Orn_DAP_Arg_deC, FT Pyridoxal-dependent decarboxylase, score 135.90, E-value FT 7.7e-40" FT misc_feature complement(15312..15356) FT /note="PS00879 Orn/DAP/Arg decarboxylases family 2 FT signature 2" FT misc_feature complement(15816..15872) FT /note="PS00878 Orn/DAP/Arg decarboxylases family 2 FT pyridoxal-P attachment site" FT CDS complement(16254..17921) FT /transl_table=11 FT /gene="SCO0316" FT /gene_synonym="SC5G9.25c" FT /product="putative DNA-binding protein" FT /note="SC5G9.25c, hypothetical protein, len: 555 aa; FT similar to hypothetical proteins e.g. TR:O50442 FT (EMBL:AL010186) Mycobacterium tuberculosis hypothetical FT protein (538 aa), fasta scores; opt: 485 z-score: 521.2 FT E(): 1.2e-21, 32.6% identity in 568 aa overlap and to FT TR:Q9Z561 (EMBL:AL035569) S.coelicolor putative FT transcriptional regulator (415 aa) (28.4% identity in 444 FT aa overlap). Contains probable helix-turn-helix motif at aa FT 505-526 (Score 1081, +2.87 SD)" FT /db_xref="GOA:Q9RL02" FT /db_xref="UniProtKB/TrEMBL:Q9RL02" FT /protein_id="CAB55673.1" FT /translation="MAAREPDRRDGRPSLEQILRLIAPGMLDVVVAPRGTGVPVADAVL FT HDPGEERDDGTWAASGLILLAVGVDAAAPEAIDVLRGAERAGAAAVVLRRGARGPRAAL FT LEAAASGRTALLTRRPGQGWTEVLGQLRTALAHSAPTGGTGVEGLRLGDLPELANTVAA FT LVGGAITIEDPQSRVLAYSRMDHEPDPMRRLTILGQEVPRWRVDELRESGFFQALWNTD FT GVVRLPADDRYAERLAVAVRHGSEILGSLWAAADGRPLAEDAAAALHTAARAAVPHLAH FT HQTWGRAAARARESAVHALLDGSGPAARVAHDAGVAPDRPYTVLVAEAYDSRDLTAVPA FT PATGGAAGQRTLDVLALQAEAYRPGCVTARSGRRLYVLIPAEDGETDPARALTATARSV FT PRGVVFAGVGPVAADLSGLPASREAAELVVRVLRERAARRPAADVVSAVAAFGEVVPEV FT SALRVLDLIAPLWQSLSGPVHAMVEHDRAHGSEYGASVGAYLDAFGDTGTAAQRLNVHP FT NTLRYRLRRARELFGVDLADPTLRLLADVGLRLARRTE" FT CDS complement(17975..19237) FT /transl_table=11 FT /gene="SCO0317" FT /gene_synonym="SC5G9.26c" FT /product="putative transmembrane transport protein" FT /note="SC5G9.26c, probable transmembrane transport protein, FT len: 420 aa; shows weak similarity to many efflux pumps FT e.g. SW:CMLR_STRLI (EMBL:X59968), cmlR, Streptomyces FT lividans chloramphenicol resistance protein (392 aa), fasta FT scores; opt: 276 z-score: 292.9 E(): 6e-09, 27.3% identity FT in 407 aa overlap. Contains hydrophobic, possible FT membrane-spanning regions" FT /db_xref="GOA:Q9RL01" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q9RL01" FT /protein_id="CAB55674.1" FT /translation="MSERATESVLRSPGIPHLLTVGAFCFAGLALLLPVSPAWAVAGGA FT DEFGAGLVTAVLMAATVLAQLCVRTALRTIGWPRTLALGALLLGLPALVQSLSDHLVPI FT LVTTALRGAGFGIVTVCGATAAAALAPRGRQGAAIGLYGLAVALPQVILTPAAPWLMGT FT FALPAIVACGVLPVLALPWTRALGRAVEARTDGPPTQDGRTGHPAPAATVLRRILLPLT FT VLLLVTAAGGAVLTFAPQFTSTPALAATGLLALTATAALARWGCGELADRIALRPITAL FT LASTACAGLALIALAVGPDGETVLPLLAGLLLLGTAYGGLQSLTLVQAFDLAGAEDRHM FT TSVAWNIGYDAGTGLGSLALGLAAQAATFSAGFAVMSAVMAAVVLAVLLTPGRPAGRTA FT GDRPRTRSRTRRSPARPRKLP" FT CDS complement(19329..20345) FT /transl_table=11 FT /gene="SCO0318" FT /gene_synonym="SC5G9.27c" FT /product="putative oxidoreductase" FT /note="SC5G9.27c, possible oxidoreductase, len: 388 aa; FT shows weak similarity to many eukaryotic and bacterial FT oxidoreductases e.g. TR:Q39617 (EMBL:U36752), LpcR-1, FT Chlamydomonas reinhardtii NADPH:protochlorophyllide FT oxidoreductase (397 aa), fasta scores; opt: 278 z-score: FT 296.3 E(): 3.8e-09, 27.4% identity in 343 aa overlap. FT Similar to TR:O53726 (EMBL:AL021932) Mycobacterium FT tuberculosis putative oxidoreductase (311 aa) (41.1% FT identity in 309 aa overlap). Similar to others from S. FT coelicolor e.g. SCJ9A.19c (cosmid SCJ9A), possible FT oxidoreductase (311 aa) (39.6% identity in 303 aa overlap). FT Contains Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase" FT /db_xref="GOA:Q9RL00" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RL00" FT /protein_id="CAB55675.1" FT /translation="MGESVLLTSTPPEHKESVIVSSAPQSRPWDVHRLPSAEGRNFLVT FT GGNAGIGYFTAEQLAATGALVVIGSRNPAKADAALASIRSRVPGARVRHLHLDLADLST FT LKSAVDGLALDLGRLDAVVHNAGGALDDPPRRETEDGHELMFGTNHLGHYALTRWLAPL FT LSAAPAGRVVTVGSFAARSERLDLDDLQSTRDYRPKRTYGRSKLAQMCFGFELDRRLRA FT AGSTVLSAVAHPGGALDSLTPPRPPVGAPTPGERLRGLPAALMVQGKDAGAWPVVRAVL FT DSDVQGGQLWGPRVFGLRGQPRREPVPAHMADPAVAARLWAASAELTGTTDPHLGFR" FT misc_feature complement(19626..20228) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 70.30, E-value 4e-17" FT CDS complement(20499..21008) FT /transl_table=11 FT /gene="SCO0319" FT /gene_synonym="SC5G9.28c" FT /product="hypothetical protein SC5G9.28c" FT /note="SC5G9.28c, unknown, len: 169 aa; probable CDS FT suggested by GC frameplot, positional base preference and FT amino acid composition" FT /db_xref="UniProtKB/TrEMBL:Q9RKZ9" FT /protein_id="CAB55676.1" FT /translation="MEAESGHAVVHQCGGRHRGQPSGNRHDLLRTRDDLFGVSGPGSHD FT HTPADPARVHSVTDCQHLARPAATRHVRQRAREEVLTPAAAQQRVQEDDVGRDHTDDDL FT AGAGHGIGQVDQAQHVRSTERGHVDRMHEQHPSLEATSRPASNLKSGRGQGSSVVRGGV FT GPVGKG" FT CDS 21110..21583 FT /transl_table=11 FT /gene="SCO0320" FT /gene_synonym="SC5G9.29" FT /product="hypothetical protein" FT /note="SC5G9.29, hypothetical protein, len: 157 aa; similar FT to the C-terminal half of SW:QOR_PSEAE (EMBL:X85015), qor, FT Pseudomonas aeruginosa quinone oxidoreductase (325 aa), FT fasta scores; opt: 223 z-score: 254.4 E(): 8.3e-07, 34.8% FT identity in 161 aa overlap and the corresponding region of FT many similar hypothetical proteins. Also similar to regions FT of polyketide synthase-type proteins e.g. SW:MCAS_MYCBO FT (EMBL:M95808), mas, Mycobacterium bovis mycocerosic acid FT synthase (2110 aa) (35.8% identity in 159 aa overlap). FT Contains PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9RKZ8" FT /db_xref="HSSP:1PQW" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RKZ8" FT /protein_id="CAB55677.1" FT /translation="MVAAASSDAKLALARDLGAEVVVDYTRADWVERVREATGGGAALV FT YDGAGGALGATSVDALADGGRFVTYGTADGFAAPDRESAARRGIRLLMPLMDGPPDQET FT ARELLGLALESAAEGRLRPAIGATYPLARAADAHRALAARTTVGKSLLLMGGE" FT misc_feature 21536..21559 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 21699..23255 FT /transl_table=11 FT /gene="SCO0321" FT /gene_synonym="SC5G9.30" FT /product="putative carboxylesterase" FT /note="SC5G9.30, probable carboxylesterase, len: 518 aa; FT similar to many eukaryotic and bacterial e.g. SW:PNBA_BACSU FT (EMBL:U06089), PrnbA, Bacillus subtilis 4-nitrobenzyl FT esterase (489 aa), fasta scores; opt: 718 z-score: 774.9 FT E(): 0, 36.3% identity in 479 aa overlap. Similar to FT TR:Q9Z545 (EMBL:AL035212) Streptomyces coelicolor probable FT carboxylesterase (502 aa) (41.3% identity in 521 aa FT overlap). Contains 2 Pfam matches to entry PF00135 FT COesterase, Carboxylesterases and PS00122 Carboxylesterases FT type-B serine active site" FT /db_xref="GOA:Q9RKZ7" FT /db_xref="HSSP:1N5M" FT /db_xref="InterPro:IPR019826" FT /db_xref="UniProtKB/TrEMBL:Q9RKZ7" FT /protein_id="CAB55678.1" FT /translation="MQREAVPVVVFKTRHGSVRGFRASGDVVAVLGVPYAAAPFGVHRF FT REPAPAPAWTGVRDGRSFGPVAPQSARLPGAPVWSPGDEDILTVNLWTPAPDGGPLPVL FT VWIHGGAYTFGSSAQPDFDGTVLARAGLVVVTLNYRIGFEGFGHVPPDGPIAHPDNRGL FT LDQVAALRWVRENIAAFGGEPGNVTVAGQSSGAASVACLMVMDRARGLFHRAIAHSPAS FT PCYPRDIAAATTREVAAAAGCPATSAGLRSTTPQALVAAADQVADGYRRDPASGSRHYD FT PSLYAPVLDDDVLPTDPLTGMAAGAARDVDLLVCHTTEEYWLLDAVGSSAKVTTDAQLA FT RFAEDFGLPDGLVAGYRAALPRAPVLDVYLAVFGDLLFGEYANRLAEVHARAGGRAFLS FT RFDRRRADPGAVVRAWHCADVPFAFGNLDDERLAFLIGGAPTAADQGLARRMVRAWADF FT AATGSPGWPPVRDSSTEATEATEATEAKVWTADPHAARTGDRAAAVRALWAEADFPVLR FT P" FT misc_feature 21735..22658 FT /note="Pfam match to entry PF00135 COesterase, FT Carboxylesterases, score 250.70, E-value 2.9e-72" FT misc_feature 22236..22283 FT /note="PS00122 Carboxylesterases type-B serine active site" FT misc_feature 22944..23186 FT /note="Pfam match to entry PF00135 COesterase, FT Carboxylesterases, score 12.90, E-value 0.0041" FT CDS complement(23244..24938) FT /transl_table=11 FT /gene="SCO0322" FT /gene_synonym="SCF12.01c" FT /gene_synonym="SC5G9.31c" FT /product="putative ABC transport ATP-binding subunit" FT /note="SCF12.01c, possible ABC transport ATP-binding FT subunit, len: >230aa; similar to many eg. SW:TLRC_STRFR FT tylosin resistance ATP-binding protein from Streptomyces FT fradiae (548 aa) fasta scores; opt: 1017, z-score: 1131.8, FT E(): 0, (69.0% identity in 232 aa overlap). Contains FT Prosite match to PS00211 ABC transporters family signature FT and Prosite match to PS00017 ATP/GTP-binding site motif A FT (P-loop)." FT /note="SC5G9.31c, probable ABC-transporter ATP-binding FT protein, partial CDS, len: >371 aa; similar ATP-binding FT components from antibiotic resistance export systems e.g. FT SW:TLRC_STRFR (EMBL:M57437), tlrC, Streptomyces fradiae FT tylosin resistance ATP-binding protein (548 aa), fasta FT scores; opt: 1517 z-score: 1597.3 E(): 0, 67.4% identity in FT 356 aa overlap. Also similar to many other putative FT ABC-transporter ATP-binding proteins. Contains Pfam match FT to entry PF00005 ABC_tran, ABC transporter, PS00211 ABC FT transporters family signature and PS00017 ATP/GTP-binding FT site motif A (P-loop)" FT /db_xref="GOA:Q8CK61" FT /db_xref="HSSP:1US8" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q8CK61" FT /protein_id="CAD55436.1" FT /translation="MRTSQLTLSHVTKRYAGRTVLDQVSLTLKPGEKAGLIGDNGAGKS FT TLLRIVAGQERPDSGEATVTAAGGIGCLPQSVPLPPTATVQDAVDLSLADLRALEAELR FT RAEQALGAGEDPEALAAYTVLVERYEARDGHDADRRVDIALHHLGLPALRRERRLGTLS FT GGERSRLALAGVLAGRPEVLLLDEPTNDLDDQAVEWLETQLRAHRGTVLAVTHDRVFLE FT RLTSTILEAEGGRVTRYGDGYNGYRTAKAAERRRRLQEHEEWRSELARNERLATGHAAR FT LGAIPRKASLANFGHGGFRARGRAHGAMSRIRNARERVERLTENPVAPPPDALAFTVRM FT ATAAEEASATGAASATLPAVQLSDVRVGDRLHLGSLGLGRRGRLLVTGPNGAGKTTLLK FT VLAGELRPDEGSVRVPGRVGHLRQEETPWPPELTVAEAFGLGRVGAADEHADTLLALGL FT FRPAELRLRMGELSYGQRRRVELARLVSEPVDLLLLDEPTNHLSPALVEELEEALTGFS FT GAIVLVTHDRALRGRFRGRRLTLPAAPGARTGQPVAVAHRPRPGSGA" FT misc_feature complement(23310..23798) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 144.30, E-value 2.1e-39" FT misc_feature complement(23484..23528) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(23754..23777) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(24411..24455) FT /note="PS00211 ABC transporters family signature." FT misc_feature complement(24804..24827) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS complement(25467..26069) FT /transl_table=11 FT /gene="SCO0323" FT /gene_synonym="SCF12.02c" FT /product="hypothetical protein" FT /note="SCF12.02c, unknown, len: 200aa;" FT /db_xref="UniProtKB/TrEMBL:Q9RK54" FT /protein_id="CAB56128.1" FT /translation="MDAVPRALRVGQYRPRCVAPAHVSVRGAQFLEAGGQLRPTVLGGG FT GKLEVDSVLHRLRVRDADEVDADRGRVRPVEAHGFQVRDARPLARRAPAERLRPEAAER FT RVVPGLEVHPYKLRRHPEPPALPRPRAARPSPRGPGRTGPDRPRRGAQQVRPVYQAPSM FT SELDPIQVTPGTTHRSLLGPQSSISMTMCEPSEVQWL" FT CDS complement(26238..28616) FT /transl_table=11 FT /gene="SCO0324" FT /gene_synonym="SCF12.03c" FT /product="putative secreted protein" FT /note="SCF12.03c, possible secreted protein, len: 799 aa; FT similar to TR:CAC45838 (EMBL:AL591786) Rhizobium meliloti FT (Sinorhizobium meliloti) hypothetical transmembrane protein FT (fragment) SMC01907, 729 aa; fasta scores: opt: 492 FT Z-score: 517.1 E(): 3.6e-21; 42.318% identity in 742 aa FT overlap. Contains possible cleavable N-terminal signal FT sequence" FT /db_xref="InterPro:IPR015943" FT /db_xref="UniProtKB/TrEMBL:Q9RK53" FT /protein_id="CAB56129.1" FT /translation="MSPKSKRTRAALAALVVAAGSLVTAGAARAEQPHHGQRHGGQQAQ FT QAQQAQQGRSSLFERTATYPVFHNRPAGEDAAAGTVAEISSVSEDGRTLVHTDAVARRI FT GFLDISDPGHPRGLGTLSLARLDDAEDEPTSVTVVGQYVLVVVNTSASHARPSGRLDVV FT SLRDRKRVASFDLGGQPDSVAVSKDKRYAAVAVENERDEEATPPGRDEGDLPQAPAGFV FT QIVDLGRGAAPAHWRTRAVPLTRADGRALPVLAEAGIAEPTDPEPEYVSINSRNQLAVT FT LQENNGVVLIDLPTGRIAKAFGAGTASVRGIDTESDGRIDQRGSIEDLRREPDAVGWID FT DRYLATANEGDWRGGTRGWSVFDSRTGKPVWDAGNSFERLAVRHGLHDEGRSGKKGAEP FT EGIAIAEYDGVPYAFVGSERDNFVAVYDVSRPTRPVFRQLLPATNGPEGLLPIPSRGLL FT AVSSEEDDAEAGVRASVSLFRMGRGTGQTPSFPGIVSADDDRGAPIGWGALGALSAAPG FT KPHRLYTVTDAAYSTTRILTVDTARRPAVITRELTVKDADGRPAGYDAEGIHARPQGGF FT WLAVEGGTGAGNKLVRLDARGVTRQVVPLPADVAAGLGKQGFEGVTATTDRRGHEVVWA FT ALQREAAGDPAGVVRLGRYDVTAGTWSWYGYRLESTGTAGDWMGLSEITVVGDRLAVIE FT RDKLNGPAARVKRIYTVDLPKSAVPSGALRILPKRLAHDVLPDLRATNGWTQEKLEGLT FT VGGDGRVYAVTDNDALDDATGETVFLDLGTARQVFGRRG" FT CDS 28899..29264 FT /transl_table=11 FT /gene="SCO0325" FT /gene_synonym="SCF12.04" FT /product="hypothetical protein" FT /note="SCF12.04, unknown, len: 121aa;" FT /db_xref="UniProtKB/TrEMBL:Q9RK52" FT /protein_id="CAB56130.1" FT /translation="MRVTGTSAHERDGVDVIVRMSGSAYDSWAGFEEITVRSCFTVRVS FT PASRWREDPDDVDCPEDPALTFAPPVRGNHFDPQDCLLARVVPGATEVRGAAPHPPDAR FT SGRPQVACALDPAAAPH" FT CDS 29333..30301 FT /transl_table=11 FT /gene="SCO0326" FT /gene_synonym="SCF12.05" FT /product="hypothetical protein" FT /note="SCF12.05, hypothetical protein, len: 322 aa; similar FT to TR:O54173 (EMBL:AL021411) hypothetical protein from FT Streptomyces coelicolor (382 aa) fasta scores; E(): FT 6.7e-12, 34.2% identity in 371 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9RK51" FT /protein_id="CAB56131.1" FT /translation="MSGIPSQGVASGMREAARALLAVLEPEQVRELRAGPDRLDTPELR FT EWTYLPGPRPGLSTEGLDGRQREVVDALLTTAHSAAGAELVRGAIEVERHPRARAGHPG FT PDRYWVRLLGDPGGDEPWGWRLNGHHLAVHVLVTAAGVRVTPHFVGAEPARTGNGPRPG FT LRPLGPEEDLARELITSLGGTARASALFAATPPDDILTRADPFADPGLLPEGLRYDRLA FT PGQQRLLERLVGRYLDRAPEAYARECWSDAVRRGLGSLSFAWAGGLAPGDRHYYCVRAP FT DFLIEYDNTQDDGNHAHSVWRHVRHDWGTDLLRGHYTEQHF" FT repeat_region 30297..30317 FT /note="Part of inverted repeat bounding insertion element FT IS1650." FT repeat_region 30297..31194 FT /note="Insertion element IS1650. Also present at FT 35521-36418bp on Streptomyces coelicolor cosmid SC6G9." FT CDS join(30321..30731,30728..31174) FT /pseudo FT /transl_table=11 FT /gene="SCO0328" FT /gene_synonym="SCF12.07" FT /gene_synonym="SCF12.06" FT /product="insertion element IS1650 transposase" FT /note="SCF12.07, partial CDS, insertion element IS1650 FT transposase, len: 148 aa; similar to many transposases. FT Identical to TR:CAB45627 (EMBL:AL079356) insertion element FT IS1650 transposase from Streptomyces coelicolor (136 aa) FT fasta scores; opt: 999, z-score: 1255.4, E(): 0, 99.3% FT identity in 148 aa overlap. Complete protein probably FT translated by ribosomal frameshifting from the upstream FT CDS." FT /note="SCF12.06, partial CDS, insertion element IS1650 FT transposase, len: 136 aa; similar to many transposases. FT Identical to TR:CAB45627 (EMBL:AL079356) insertion element FT IS1650 transposase from Streptomyces coelicolor (136 aa) FT fasta scores; opt: 952, z-score: 1212.6 E(): 0, 99.3% FT identity in 136 aa overlap. Contains Pfam match to entry FT PF01511 Transposase_6. Complete protein probably translated FT by ribosomal frameshifting into the downstream CDS." FT misc_feature 30441..30701 FT /note="Pfam match to entry PF01511 Transposase_6." FT repeat_region complement(31174..31194) FT /note="Part of inverted repeat bounding insertion element FT IS1650." FT CDS 31235..32365 FT /transl_table=11 FT /gene="SCO0329" FT /gene_synonym="SCF12.08" FT /product="putative esterase" FT /note="SCF12.08, possible esterase len: 376 aa; similar to FT many e.g. TR:O87861 (EMBL:Z15137) esterase A from FT Streptomyces chrysomallus (389 aa) fasta scores; opt: 503, FT z-score: 581.9, E(): 4.6e-25, 34.9% identity in 378 aa FT overlap" FT /db_xref="InterPro:IPR001466" FT /db_xref="UniProtKB/TrEMBL:Q9RK50" FT /protein_id="CAB56134.1" FT /translation="MGSEPDAVPGPSLQQKVQGVLDELVGTGAERGLQVAVYHHGALVV FT DAVAGVADSRTGRRVAPETPFFGFSAGKVMTSLVAHLLVKSGRIGYDTPVAELWPRFGA FT HGKGTTTLRHVLTHSAGVPAMPRDIGPGDLSDWSRVCTALADAAPRWRPGTRTGYHSYT FT YGFLVGEIARRATDRPMRQLLREWVTEPLGLEGNLYFSVPRTDLARLAHLEDAHLEDVR FT PPAAAATDDEAVLAPWELRPTAELGNNAEVLRADVPSVGTFTARGIAAMNAALLDGRLI FT DPGQLAEVTAVAFEGTDQVFGHHVRLGLGYPLGGVGSRTGEALTTFGWIGGGGSYVCAD FT TAAGIALAVTKTLLTPHFDTARRLTDLITAELGPPV" FT CDS 32504..33253 FT /transl_table=11 FT /gene="SCO0330" FT /gene_synonym="SCF12.09" FT /product="putative short chain oxidoreductase" FT /note="SCF12.09, probable short chain oxidoreductase, len: FT 249 aa; similar to many eg. TR:O86853 (EMBL:AJ007731) FT 3-ketoacyl-ACP/CoA reductase from Streptomyces coelicolor FT (244 aa) fasta scores; opt: 515, z-score: 576.2, E(): FT 9.6e-25, (40.2% identity in 244 aa overlap and to FT SW:FABG_BACSU (EMBL:U59433) Bacillus subtilis FT 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) FT FabG, 246 aa; fasta scores: opt: 473 Z-score: 524.5 E(): FT 1.4e-21; 37.500% identity in 248 aa overlap. Contains Pfam FT match to entry PF00106 adh_short, short chain FT dehydrogenase; Pfam match to entry PF00678 adh_short_C2, FT Short chain dehydrogenase/reductase C-terminus and two FT Prosite matches to PS00061 Short-chain FT dehydrogenases/reductases family signature" FT /db_xref="GOA:Q9RK49" FT /db_xref="HSSP:1GZ6" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RK49" FT /protein_id="CAB56135.1" FT /translation="MSTPESNRVALVTGGSGGIGRVVAERLARDGFAVAVQYAGNRAKA FT EETVAAINAVGGRALAVGGDVADEDAMGTAFDTVRSAFGGIDVVVNTAGIMILAPVETL FT DLADLDRMHRTNIRGTFVVNQQAARTVRSGGAVVNFSTSVVRTQLPTYGAYGAYVASKA FT AVEAMTLVLARELRGRDITVNAVAPGPTATPLFLQGKDEGTVDKFAKATPLERLGRPED FT IAETVAFLAGPARWINGQVLYANGGLA" FT misc_feature 32525..33085 FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 175.50, E-value 8.5e-49" FT misc_feature 32936..33022 FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature." FT misc_feature 33146..33235 FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 33.90, FT E-value 3.8e-06" FT CDS 33311..34210 FT /transl_table=11 FT /gene="SCO0331" FT /gene_synonym="SCF12.10" FT /product="putative short chain oxidoreductase (putative FT secreted protein)" FT /note="SCF12.10, possible short chain oxidoreductase FT (putative secreted protein), len: 299 aa; similar to many FT e.g. TR:CAB51136 (EMBL:Y18817) short chain oxidoreductase FT from actinorhodin biosynthesis cluster of Streptomyces FT coelicolor (276 aa) fasta scores; opt: 358, z-score: 403.3, FT E(): 4.1e-15, 34.6% identity in 280 aa overlap. Contains FT Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase" FT /db_xref="GOA:Q9RK48" FT /db_xref="HSSP:1FDS" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RK48" FT /protein_id="CAB56136.1" FT /translation="MSPTGTVVVITGASSGFGALTARALADAGHTVHAGMRHTAGRNAP FT QVQAALDYSREHGVDLRPVELDVNSQASVDAAIAGIEAEHGHIDVLVHNAGHMSTGPAE FT AFTPDQLAALYDVNVLSTQRVNRAALPGMRRRGQGLVLWVSSSSVKGGTPPYLAPYFAA FT KAAMDSLAVSYAAELARWGVETSIVVPGSFTSGTNHFAHSGRPDDAAVEAEYETRYAGL FT MEQVADKLAALAPEGASATLVSEEIARIVALPAGWRPFRVHIDPADDGSQEVSDTADRV FT RSAFLDRIGLADLLGVER" FT misc_feature 33326..33898 FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 123.30, E-value 4.4e-33" FT CDS 34529..35149 FT /transl_table=11 FT /gene="SCO0332" FT /gene_synonym="SCF12.11" FT /product="putative transcriptional regulator" FT /note="SCF12.11, possible transcriptional regulator, len: FT 206 aa; similar to many e.g. TR:AAD31815 (EMBL:AF129856) FT transcriptional repressor from Pseudomonas fluorescens (208 FT aa) fasta scores; opt: 275, z-score: 343.1, E(): 9.3e-12, FT 30.0% identity in 200 aa overlap. Contains probable FT helix-turn-helix motif (+5.38 SD) 45-66aa." FT /db_xref="GOA:Q9RK47" FT /db_xref="InterPro:IPR012287" FT /db_xref="PDB:2ZB9" FT /db_xref="UniProtKB/TrEMBL:Q9RK47" FT /protein_id="CAB56137.1" FT /translation="MANDANGRPAPGSRGRGRRPAEEVRAEVLHAVGELLLTEGTAQLT FT FERVARVSGVSKTTLYKWWPSKGALALDGYFHAVEDTLAFPDTGDVRADLLAQLRAFTH FT VMTRTPGGRILTELIGAAQTDADLATAYRQLYSAQRRALAAERLRHARELGQIRPDVDV FT QVLVDQLWGAVYHRLLIPDEPVDDAFVTALVTNLLDGVCPRPA" FT CDS complement(35223..36734) FT /transl_table=11 FT /gene="SCO0333" FT /gene_synonym="SCF12.12c" FT /product="putative dioxygenase (putative secreted protein)" FT /note="SCF12.12c, possible dioxygenase (putative secreted FT protein), len: 503 aa; similar to many of undefined FT function and to TR:Q53353 (EMBL:S65040) FT lignostilbene-alpha,beta-dioxygenase from Pseudomonas FT paucimobilis (485 aa) fasta scores; opt: 529, z-score: FT 596.3, E(): 7.3e-26, (31.6% identity in 493 aa overlap)" FT /db_xref="GOA:Q9RK46" FT /db_xref="InterPro:IPR004294" FT /db_xref="UniProtKB/TrEMBL:Q9RK46" FT /protein_id="CAB56138.1" FT /translation="MGSHSRRRILRGAAVAAAGSVVGSGLGPGFFSAAAQATPAAPKGG FT SAPATPFLEGAFAPVTEELTAFDLDVVGRIPADLDGRYLRNGPNALGIEDVRAHHWMIG FT DGMVHGVRLRGGRAEWYRNRWVRSSQVTAKLGETYPGQAPPDDFPCNTHVIPYHGRILA FT LQEGGPLPYELDGELNTLRPYDFRATQKGAFAAHTKYDAVADELHAIAYYPTWDHVRHI FT VVDRTGRARPATRIPVADAPMMHDFALTEKYVVIVDVPITFDGAAAEAGAIVPYVWNDR FT HPMRLGLLPRTGGTTRWFEIDPVYYSHTLNAYDQGDTVVLEYIGFPAPFYAAGRGVGGP FT SATGSPTLDRWTVDLGAARVRSTRLDDRPQEFPRINESLVSRRHRYAYTACAAEMWRAY FT ETVDGVCPDEKFTNYLVKHDMLRGSRQLHRFPRGAAVGEPVFVPRRGARDEDDGYVLSY FT VNDPDRGATDLVILSAQNFGGRPRARVRLPGRVPLGFHGSWVPDA" FT CDS 36948..37292 FT /transl_table=11 FT /gene="SCO0334" FT /gene_synonym="SCF12.13" FT /product="putative secreted protein" FT /note="SCF12.13, putative secreted protein, len: 111 aa;" FT /db_xref="UniProtKB/TrEMBL:Q9RK45" FT /protein_id="CAB56139.1" FT /translation="MLQLAGTTAATTAVGPLAGGSPAHGAALPPARAGIGAPAFPFGLG FT RVRPTATLLDQGDGTCTIRDARGKLLPVQNDSPAAGAFVAQEADDGAADNRWRILRRTA FT IDTRVRVVPG" FT CDS 37333..40467 FT /transl_table=11 FT /gene="SCO0335" FT /gene_synonym="SCF12.14" FT /product="putative secreted protein" FT /note="SCF12.14, putative secreted protein, len: 1044 aa" FT /db_xref="GOA:Q9RK44" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q9RK44" FT /protein_id="CAB56140.1" FT /translation="MGPVSLPVGRRLLLQLLGATGAAAALQPALGSPSAAAAASGAAPS FT VDPPDDVAATYHRVLLRHTRWSETQWDEAKGAYSDRNFGFAVVLGHAVLLTHGTFDEDA FT AGVDRETLRRRTLATLRHYAASNRLTGGTQWGRTLFFDTTFQSYFVLAAHLLWDELDAA FT TRSAVDTITREQAAYTHSLGTGDDPYSGSWTPNGLAGGYVGDTKLEEMGLYAQTLAPAL FT AWAPDDRRRSEWAADYGTWSRNEGGLPPADLANPARVDGVPVSHNTAHNAYDTFIVENH FT GSFGPHYQEEMWRTSGRNAAHFLAAGQPLPEVLTRQPNAEPLWRTLLGVMSDAGEPLMP FT MVDDREHLYGRDVIPLAFLSRVAGDRAAARAETELAARLEAYQAYPPEYRLAKFSGEPK FT YEPEARAELAISYLLHVWPQAGPRVRPLSREELFAFASGVTDFGTGPGLVSHQSPAAWA FT GTVTKPGFVKFAWQPAHDDWLFRLGGATPMFLPSTAAEVTGRTVRVHTALRDGFDGSAT FT VLRLGEGFAGYATLPTGAVVYACEGPGAAASRLEVHNLTMPGVAGLDGSRTYRFAEGSA FT TVRAQDTTPSAAGRVDELAFPGTTVRHLRMLGVQPDPAYGYSLYAVEARDGAEGPDLAR FT GGTATASSQSAGMGPELAVDGNGASRWAVSREDRRRADSWWAVDLGAERALDRVTLRWE FT AAAGRSYRVQGSPDGERWTDLATGPAPSLRSGGGWLDVDGRAGLVVRGGSEHRLAVYGD FT TIVPAEGAREPLVIEGHCGVSAGDLSALARRAAPTAGDGRVRAARVDGYLSLFNLSAQE FT VETRVAVPQQGGSREVYEGDQTVTREGIDYGARLDAASASLLAPRFTLSALSGRSLPSG FT LRVRVADGATLILSGAHCRLRIEAQGRGTEATVRGGRETRVTLRGAQAFPHHDHALGRN FT TFPTNPLPPGMSGPGAAVDGDPDTAWHPGRDGRMVVDLGTRTGVRWVEARWRTGAAPAA FT RVEFSTDGVRYQQAGTLDGRGRVRRLTRAGSARYVAVTVQGAPHAHEGLVRLSVG" FT CDS complement(40521..41630) FT /transl_table=11 FT /gene="SCO0336" FT /gene_synonym="SCF12.15c" FT /product="putative integral membrane protein" FT /note="SCF12.15c, possible integral membrane protein, len: FT 369aa; contains possible membrane spanning hydrophobic FT regions." FT /db_xref="GOA:Q9RK43" FT /db_xref="InterPro:IPR005097" FT /db_xref="UniProtKB/TrEMBL:Q9RK43" FT /protein_id="CAB56141.1" FT /translation="MTETSGTTSGNRTNDEVWIVGATGRVGRGVTGRLAARGLTVVPVG FT RSRERMAAAGAAAGLPADAKTVVADSAERIAEEVLRQRPRAVVNTMGAYATTAPVIARA FT CMSVGGHYVDQANDVVAVEGLLALHEDATRAGSTLVTGAGFGVLATEAVVAKLCEERPA FT PHRVRIDSVASVAVEAGAVGAALATSIVDTLTAGGRRYADGRLVASRLGADPQRLTFPD FT GTSARSAGVASGELVAARAASGAPFVTATSSLAPSTPLLRAVVPALGRLLSVPALRRLA FT VARLGRVTVKAAPRPREHSWGHAVVEWADGTRREGWLRADEGMDFTADVTATVTELLAR FT GAGRPGAWTPAGALGPDVATSAGGTFVLD" FT CDS 41752..42318 FT /transl_table=11 FT /gene="SCO0337" FT /gene_synonym="SCF12.16" FT /product="putative transcriptional regulator" FT /note="SCF12.16, probable transcriptional regulator, len: FT 188 aa; similar to many transcriptional regulators from FT Streptomyces spp. e.g. SW:TCMR_STRGA tetracenomycin C FT transcriptional repressor from Streptomyces glaucescens FT (226 aa) fasta scores; opt: 152, z-score: 176.0, E(): FT 0.019, 28.1% identity in 203 aa overlap. Contains Pfam FT match to entry PF00440 tetR, Bacterial regulatory proteins, FT tetR family and a possible helix-turn-helix motif (+3.98 FT SD) 29-50aa." FT /db_xref="GOA:Q9RK42" FT /db_xref="InterPro:IPR012287" FT /db_xref="PDB:2DG7" FT /db_xref="UniProtKB/TrEMBL:Q9RK42" FT /protein_id="CAB56142.1" FT /translation="MARWDPGAEQRLKRAALELYSEHGYDNVTVTDIAERAGLTRRSYF FT RYFPDKREVLFGGSELLPPAVARAVLAADPGAAPLTAVLDAMSQVGAQLVAQVEGAAQR FT RAVIDASPELQERERTKSAAISRAVQDALVRRQVDADTAELVAQLATVAFGSAFRRWID FT AEGHADFGSCLDTVTDRLRAVLTGT" FT misc_feature 41785..41916 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 33.50, E-value FT 1.4e-07" FT CDS complement(42370..42909) FT /transl_table=11 FT /gene="SCO0338" FT /gene_synonym="SCF12.17c" FT /product="putative dehydrogenase" FT /note="SCF12.17c, possible dehydrogenase, len: 179 aa; FT similar to the C-terminal many proposed glucose-6-phosphate FT dehydrogenase eg. TR:AAD36231 (EMBL:AE001772) from FT Thermotoga maritima (496 aa) fasta scores; opt: 314, FT z-score: 381.8, E(): 6.5e-14, (42.5% identity in 146 aa FT overlap). Contains Pfam match to entry PF00479 G6PD, FT Glucose-6-phosphate dehydrogenase." FT /db_xref="GOA:Q9RK41" FT /db_xref="InterPro:IPR001282" FT /db_xref="UniProtKB/TrEMBL:Q9RK41" FT /protein_id="CAB56143.1" FT /translation="MRAAASQSATRACWNSTAGAWAGTRFRLRSGKALGTDRKEVAVRF FT RSVPHLPFGQDQDVRPNVLRFGLEPESLSVDLTATGSRPETLTQLSLTARMDTPDLPAY FT GRLLLDVLRGDPALSIRGDEAEEAWRVVEPVLSAWERGLVPLEEYPAGSDGPPPRHATP FT ERRDDLLHEESVMRAE" FT misc_feature complement(42442..42603) FT /note="Pfam match to entry PF00479 G6PD, FT Glucose-6-phosphate dehydrogenase, score 59.80, E-value FT 4.1e-19" FT misc_feature 42992..43420 FT /note="Pfam match to entry PF00389 2-Hacid_DH, D-isomer FT specific 2-hydroxyacid dehydrogenases, score 106.10, FT E-value 4e-43" FT CDS 42992..43561 FT /transl_table=11 FT /gene="SCO0339" FT /gene_synonym="SCF12.18" FT /product="putative dehydrogenase" FT /note="SCF12.18, possible dehydrogenase, len: 189 aa; FT similar to a region from many proposed dehydrogenases e.g. FT SW:SERA_METJA D-3-phosphoglycerate dehydrogenase from FT Methanococcus jannaschii (524 aa) fasta scores; opt: 415, FT z-score: 508.1, E(): 6e-21, 40.8% identity in 179 aa FT overlap. Contains Pfam match to entry PF00389 2-Hacid_DH, FT D-isomer specific 2-hydroxyacid dehydrogenases" FT /db_xref="GOA:Q9RK40" FT /db_xref="HSSP:1MX3" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RK40" FT /protein_id="CAB56144.1" FT /translation="MLGLLSFGAIARLVAERARAFGVEVWAHDPFVDESEIRAARVRPV FT SFDDLVEGADHLVVQAPLTPQTHHTFDRATLRRMKPTAVLVNTARGPIVEDAALYEALT FT GGWIAGAALDDIEEEPAKQRDWRPNNPLFELPNVVVTPHAAYYSEEAIGTVRTIAAEEA FT VRVLTGEPARYPVNEPAAGSHRAEGA" FT CDS complement(43578..44165) FT /transl_table=11 FT /gene="SCO0340" FT /gene_synonym="SCF12.19c" FT /product="hypothetical protein" FT /note="SCF12.19c, unknown, len: 195aa;" FT /db_xref="UniProtKB/TrEMBL:Q9RK39" FT /protein_id="CAB56145.1" FT /translation="MGAMSRTTAALRLRRAITRTRDATRERAPVGRRPEEADDVRGTFA FT TDGALGFDPFPFLRALHDAGSHAVVIGQVAGIMHGSTELTGDLDLLWDGTPAEARALRS FT ALAACGCAEPPDLDRAQAAYEVTGAGGDLCTPALPWGDMDVSPCLARAETTHDPSGFTV FT RYAALDDLIRMRRALGRPKDHRRADELTRLRS" FT CDS complement(44234..46663) FT /transl_table=11 FT /gene="SCO0341" FT /gene_synonym="SCF12.20c" FT /product="putative large secreted protein" FT /note="SCF12.20c, possible large secreted protein, len: 809 FT aa; similar to TR:CAB36703 (EMBL:AL035521) hypothetical FT protein from Arabidopsis thaliana (thale cress) (847 aa) FT fasta scores; opt: 903, z-score: 959.2, E(): 0, 38.7% FT identity in 775 aa overlap" FT /db_xref="GOA:Q9RK38" FT /db_xref="InterPro:IPR019546" FT /db_xref="UniProtKB/TrEMBL:Q9RK38" FT /protein_id="CAB56146.1" FT /translation="MPEFSRRNVLAAAGASAAATALSAAPAPAAPQTADTAASAAPGED FT HAAAPMRLWYRAPAQEWLEALPVGNGRLGAMVFGGTDTERLQLNEDSLWAGGPGDYARP FT DAVRHLAEIRRLVVEEKWNRAQRLIDAEFLGSPSEQAAYQVLGDLELTLAGEGEAADYE FT RELDLETAVARTTYTRGGVRHVREVFASAPDQVLVVRLSADTPGAVGFTARFTSPQRSG FT GSAVDAHTIALDGVGGDWYGRPGSVRFRGLARAESEGGRVSTDGGTLTVEGADAATLVI FT SLATSYRNYLDVGADPASRARNHLAPAARKPYAHLRTRHVADHRRLFGRVALDLGPSER FT AELPTDERIPLFADGKDPQLAALYFQYGRYLLASCSRSPGQPANLQGLWNDSLNPAWES FT KYTVNINFEMNYWPAGPGNLAECWDPAVRMVHELAESGTRTAKALYDAPGWVLHHNTDG FT WRGTAPVDAAQYGMWPTGGAWLCVMLWDHYRFTGDTGALSRNYPVMKGAVEFFLDTLQV FT DAETGWLVTNPSQSPEVTHHQDEGESVSICAGPTMDMQLLRDLFDAYRQAAEVLDRDSR FT LVGRVTEVRDRLAPTRVGHLGQIQEWLVDWEEAALVRSRHVSHLYGVFPSAQITPRGTP FT ELAAAAKKSLELRGTAGQGWSLAWKINMWARLLEPARAYQHLADLLTPARTAPNLFDLH FT PPFQIDGNFGGVSGITEMLLQSHAGEIELLPALPEAWPTGSFRGLRARGGFEVDLEWTG FT AGITRAEVRSLLGNPVRIRTPHPVRVEGADADRSEEAVVSFATHRGGRYRLAPVTP" FT CDS complement(46817..48706) FT /transl_table=11 FT /gene="SCO0342" FT /gene_synonym="SCF41.01c" FT /gene_synonym="SCF12.21c" FT /product="putative secreted protein" FT /note="SCF41.01c, partial CDS, possible secreted protein, FT len: >350 aa. Contains a possible N-terminal signal FT sequence." FT /note="SCF12.21c, partial CDS, unknown, len: >533aa;" FT /db_xref="InterPro:IPR006626" FT /db_xref="UniProtKB/TrEMBL:Q8CK60" FT /protein_id="CAD55438.1" FT /translation="MPTTQVRPVRRRTARLPLLLAAGALLVGGATVGTPDASAQPAGCR FT ATELFVSPDGNDKAKGTKDKPFKTIEKARDHIRDKGLNRPGRMRCDIHVNLRAGDYPVN FT RTVELDDRDSGAGGHQVVYRSYDGPGKARVTGAEPVTGWEEYKDGIYRADVGTDNPFYT FT LFEDGTRATTARYPNRKSEEEWAPYLTSTLPEPEKEAVHQWLYSNPGDWDATWDLGNAQ FT AVVWSGGSWSWFTDTVPIRDWNPAKNQMTLKYWTRYALNNSGGGSRYFLQNSLDFLDQA FT GEYYLDFKKGQLYYKPRGDIDDVTVLRPTVKTLFDLAGTAPDRRVQNVTLDGLALQYTD FT FVDWYRNGWISDGDSGEVHKYPEYDRQIEMPRNRFGAVSVTNSKDVTLSRLKISDTGYH FT AVYALAANDHLTVRDSLLENIGADGIKVEGPYPGEGNTSNGHLLTNNYITHYGELNPGD FT ASGIELMNTGHNTVSHSHVKHSARYGISLEVRPEVALKDNYARGNTFEYLRIDEAGLDS FT GDMGAFYTYGVNNVEPYPMDNHVRQMVVGDVIPDESMPDSGTRGIHMDAGGCGFTFEDI FT EVGRTTDQSYQSYQCNDVKNTNWEDGYDASRMEYDKIGVTAGFPYPLPDGDTQ" FT RBS complement(48712..48716) FT RBS 48807..48810 FT CDS 48814..49083 FT /transl_table=11 FT /gene="SCO0343" FT /gene_synonym="SCF41.02" FT /product="hypothetical protein SCF41.02" FT /note="SCF41.02, unknown, len: 113 aa. Contains a PS00197 FT 2Fe-2S ferredoxins, iron-sulfur binding region signature." FT /db_xref="InterPro:IPR006058" FT /db_xref="UniProtKB/TrEMBL:Q9RJW7" FT /protein_id="CAB55705.1" FT /translation="MRKPELEPEPDGSRNRSRCGSRNRRHGSRCRAGPCSGCGGFVPSS FT GGVAPVADAVRSGMGRGPPLRTPAPVEHPHGIAYTISGSLIEQR" FT misc_feature 48901..48927 FT /note="PS00197 2Fe-2S ferredoxins, iron-sulfur binding FT region signature" FT CDS 49137..50381 FT /transl_table=11 FT /gene="SCO0344" FT /gene_synonym="SCF41.03" FT /product="putative GntR family DNA-binding regulator" FT /note="SCF41.03, possible GntR family DNA-binding FT regulator, len: 414 aa. C-terminus similar to Streptomyces FT coelicolor TR:Q9ZBS9 (EMBL; AL034446) putative GntR family FT transcriptional regulator SC1A9.23 (273 aa), fasta scores FT opt: 332 z-score: 363.0 E(): 7.2e-13 31.9% identity in 254 FT aa overlap. The N-terminus is weakly similar to other FT DNA-binding proteins e.g. Clavibacter michiganensis subsp. FT sepedonicus TR:O86023 (EMBL; AF079817) putative transposase FT (320 aa), fasta scores opt: 158 z-score:0.0 E(): 0.0 30.04% FT identity in 233 aa overlap. Contains a Pfam match to entry FT PF00392 gntR, Bacterial regulatory proteins, gntR family. FT Contains two potential helix- turn-helix motifs: between aa FT 135..156 score (+5.36 SD) and residues 69..90 score (+4.14 FT SD)." FT /db_xref="GOA:Q9RJW6" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9RJW6" FT /protein_id="CAB55706.1" FT /translation="MTKGATNSRPVSHKFTHPRKRGAMTDPVLPEFPQLSAEDRAALAE FT LARRQQAGLRLRGRIVLACAEGLTNAEVAQRLTVSPTTVAKWRERYLRRGLAGLHDAPR FT SGRPRSSNRQEAEARIAAVVEQARAGAPVPSTRSLSDTLGLSQSTVARIWREQEARLPE FT RPDGRPSRPRGAADGQEGGEASRTRGGPVPGTPRMPRQLLSDHVYALLRDWIVSGRLAP FT GQRLVESEIARGFGTSQAPPREAIKRLAYEGLVISQPHRGTYVAQVSERQAQDIRDIRV FT MFEEYAARRVAGRLDAEHTRLLAEDVTRLRRAAAEDDIGAFRDADMSFHRHVCEAARNA FT ALIRLWRMIESSLWDLHVLGDPRYAGGWGAMAEHHAELLDVLRSGDPDAAGPMFADHAA FT GETARYLTDGSGPAT" FT misc_feature 49755..49931 FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 54.90, E-value FT 2e-15" FT CDS complement(50419..51201) FT /transl_table=11 FT /gene="SCO0345" FT /gene_synonym="SCF41.04c" FT /product="probable IclR family regulator (putative secreted FT protein)" FT /note="SCF41.04c, probable IclR family regulator (putative FT secreted protein), len: 260 aa. Similar to many e.g. FT Agrobacterium tumefaciens TR:AAD43987 (EMBL:U59485) AttJ FT (275 aa), fasta scores: opt: 354 z-score: 406.3 E(): FT 2.8e-15 31.6% identity in 237 aa overlap and Streptomyces FT coelicolor TR:CAB45040 (EMBL:AL078635) putative FT transcriptional regulator (248 aa), fasta scores: opt: 333 FT z-score: 383.3 E(): 5.3e-14 32.3% identity in 248 aa FT overlap. Contains a Pfam match to entry PF01614 IclR." FT /db_xref="GOA:Q9RJW5" FT /db_xref="InterPro:IPR005471" FT /db_xref="UniProtKB/TrEMBL:Q9RJW5" FT /protein_id="CAB55707.1" FT /translation="MSTRDGSVWASAAPAPAVLRAGAILDALADARGRALSPAQLAAAA FT GGIPRASVVNICAALREQELVHAVDGGFALGPGLLRLAQSYLDAFDPVRSFREQVSRLG FT DREETLQLATMDGADVVYLAVHEGTVLMRLTSRAGARLPVTCTALGKAMLAGLDDSGVC FT ELLASREPFEARTPWSLTTLDALLAEVREVRTAGHAVDDQEAAEGIVCVAAAVPGPAGG FT GRSFAVSSSLLKSEATPERVAELAALIKGVVRRMGGAA" FT misc_feature complement(50425..50985) FT /note="Pfam match to entry PF01614 IclR, , score 85.60, FT E-value 1e-21" FT CDS 51474..52352 FT /transl_table=11 FT /gene="SCO0346" FT /gene_synonym="SCF41.05" FT /product="putative 2-hydroxyhepta-2,4-diene-1,7-dioate FT isomerase" FT /note="SCF41.05, possible 2-hydroxyhepta-2,4-diene-1,7- FT dioate isomerase, len: 292 aa. Similar to many e.g. FT Mycobacterium leprae TR:O33119 (EMBL; Z99263) possible FT 2-hydroxyhepta-2, 4-diene-1,7- dioate isomerase (242 aa), FT fasta scores opt: 491 z-score: 566.1 E(): 3.5e-24 40.6% FT identity in 212 aa overlap, Streptomyces coelicolor FT TR:O86527 (EMBL; AL031124) hypothetical 28.2 KD protein FT SC1C2.27 (261 aa), fasta scores opt: 465 z-score: 479.6 FT E(): 1.9e-21 40.0% identity in 220 aa overlap and to the FT C-terminus of Escherichia coli SW:HPCE_ECOLI (EMBL; X75028) FT homoprotocatechuate catabolism bifunctional FT isomerase/decarboxylase (405 aa), fasta scores opt: 479 FT z-score: 549.1 E(): 3.1e-23 42.8% identity in 187 aa FT overlap. Contains a Pfam match to entry PF01557 FT FAA_hydrolase." FT /db_xref="GOA:Q9RJW4" FT /db_xref="HSSP:1GTT" FT /db_xref="InterPro:IPR002529" FT /db_xref="UniProtKB/TrEMBL:Q9RJW4" FT /protein_id="CAB55708.1" FT /translation="MKLVRLGDPGRERPAVIDDRGVTRDLSSLTSDIDGAFLAADGIAR FT TRRALADDVLPPLRTEGLRFGPPVARPGAVVCIGQNYAAHAAESGSEPPTRPVIFFKPP FT NTVVGPNDEVEIPRGSARTDWEVELAVVIGRTARYLDSPGQALEHVAGYAVSNDVSERD FT FQLEHSGGQWSKGKSCATFNPLGPFLVPADEVPDVQALRLRSFVNGEPRQDSRTADMIF FT SVAQLVYDLSQYLVLDPGDVINTGTPEGVALSGRFPYLRPGDVMEIEIEGLGRQRQALV FT PARTSSQSSLV" FT misc_feature 51738..52241 FT /note="Pfam match to entry PF01557 FAA_hydrolase, score FT 226.00, E-value 5.6e-64" FT CDS 52529..53779 FT /transl_table=11 FT /gene="SCO0347" FT /gene_synonym="SCF41.06" FT /product="possible racemase" FT /note="SCF41.06, possible racemase, len: 416 aa. Similar to FT Pseudomonas putida SW:MANR_PSEPU (EMBL; M19043) mandelate FT racemase (EC 5.1.2.2) (359 aa), fasta scores opt: 322 FT z-score: 326.6 E(): 7.7e-11 27.9% identity in 366 aa FT overlap. Contains a Pfam match to entry PF01188 MR_MLE, FT Mandelate racemase / muconate lactonizing enzyme family. FT This gene is duplicated on this cosmid and shares 74.3% FT identity, in 378 aa overlap, with the downstream gene, FT SCF41.17. Note the predicted protein product of SCF41.06 is FT 36 aa longer than that of SCF41.17" FT /db_xref="GOA:Q9RJW3" FT /db_xref="InterPro:IPR001354" FT /db_xref="UniProtKB/TrEMBL:Q9RJW3" FT /protein_id="CAB55709.1" FT /translation="MKITGFRSLTTVHRWGRPVGDANGFVAQGVTEVPVLLVETDGGLT FT GVGLGAHGDAERVFPALDGQDPRAVTTLYDRMLAHTFKSGHAGTAFGTIGAFDTALWDL FT KAKMAGEPLWRTLGAADRFVPGYASGLDIALDEEELVALYSGWAARGFTGAKLKGGLDT FT ERDIGRLRAVAEVLRPNTRSPALMLDVNESWGRHQAVRLLARIEDRVELAWIEEPVRRW FT DARGHRAVGRAGRTAVASGENLTGLEQFRPLLAADALQVVQAAGVWGITHFLRVATLAH FT GHDLPVSPVGYHANPLAHAAAAVPNHLVTEVQDIGTPAGLTVDQAIEDGGIVLGDAPGL FT GITVDESALAAPRQNAGWARPDGPHVRPRDAGLRLVPEPGPPGPAARVRAGTPSLGVPG FT PVHRPARSEHTERENTP" FT repeat_region 52530..53654 FT /note="This repeat unit is 76% identical to the repeated FT region complement(15980..17108)." FT misc_feature 52589..53530 FT /note="Pfam match to entry PF01188 MR_MLE, Mandelate FT racemase / muconate lactonizing enzyme family, score 13.80, FT E-value 3.9e-09" FT CDS 53776..54795 FT /transl_table=11 FT /gene="SCO0348" FT /gene_synonym="SCF41.07" FT /product="possible 2-hydroxyacid-family dehydrogenase" FT /note="SCF41.07, possible 2-hydroxyacid-family FT dehydrogenase, len: 339 aa. Similar to Mycobacterium leprae FT SW:SERA_MYCLE (EMBL; Z99263) D-3-phosphoglycerate FT dehydrogenase (EC 1.1.1.95) (PGDH) MLCB637.25 (528 aa), FT fasta scores opt: 452 z-score: 525.4 E(): 6.5e-22 36.7% FT identity in 286 aa overlap and Pyrococcus abyssi FT TR:CAB49675 (EMBL; AJ248285) SERA-like protein (307 aa), FT fasta scores opt: 437 z-score: 511.6 E(): 3.8e-21 32.0% FT identity in 309 aa overlap. Contains a Pfam match to entry FT PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid FT dehydrogenases" FT /db_xref="GOA:Q9RJW2" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RJW2" FT /protein_id="CAB55710.1" FT /translation="MTRPRAVLAMNPRLVHAVFDEAALARLRRAADIDTGQVLAELDSA FT RSRDALAGAEILVAGWDAPVVRAEHLPGTERLRAVVYAGGVAATCLEDPAAFAARGVVA FT ANARAANSGPVAEYTLAMILLANKRVLAEERRYRASRTLPDHFGAYAGRGNYRQTVGIV FT GASTVGRAVLGLLRPFDLDVLLYDPTLTAEQAAALGARLVPLDELMAHSRVVSLHQPLT FT PATRGQIDAGRLALMPDGATLVNTARGAVVDQDALLAEVRTGRIDAVLDVTEPEPPDPG FT SELWALDNVVLTPHLAGSLGGELHRIGDAVADEVERFATGRPFAHPEDLAASARTRVW" FT misc_feature 54052..54660 FT /note="Pfam match to entry PF00389 2-Hacid_DH, D-isomer FT specific 2-hydroxyacid dehydrogenases, score 150.80, FT E-value 1.9e-61" FT CDS 54801..55805 FT /transl_table=11 FT /gene="SCO0349" FT /gene_synonym="SCF41.08" FT /product="possible oxidoreductase (putative secreted FT protein)" FT /note="SCF41.08, possible oxidoreductase (putative secreted FT protein), len: 334 aa. Similar to Pseudomonas sp. FT TR:Q52472 (EMBL; D32042) L-fucose dehydrogenase (329 aa), FT fasta scores opt: 960 z-score: 1078.8 E(): 0 48.4% FT identity in 318 aa overlap" FT /db_xref="GOA:Q9RJW1" FT /db_xref="InterPro:IPR001395" FT /db_xref="UniProtKB/TrEMBL:Q9RJW1" FT /protein_id="CAB55711.1" FT /translation="MRSRTLARGPVLTALGLGAAQLGNLARKTSDTDARGAVDAAWDSG FT VRYFDTAPHYGLGLSERRLGAALARRPRAEYTVSTKVGRLLVPSPETAHRQDDGGFAVP FT AAFRRDWDFSRDGILRSLEGSLTRLGLDHVDIVYLHDPDEHWQQASTTGVDTLVGLRDQ FT GVVKAVGVGMNQAAMLAEFVRRSDVDLVMVAGRHTLLDQSAQDELLPLARERGVGVVAA FT AVYNSGLLAADRPPGDATYDYQPASRELIARADALADVCERHGVTLPEAAIAYPLRHPA FT VVSVVLGARDAGQSRTNAARLAAGVPNALWTELADLGLLPEVPGAPSTPGEPS" FT CDS 55802..56686 FT /transl_table=11 FT /gene="SCO0350" FT /gene_synonym="SCF41.09" FT /product="conserved hypothetical protein" FT /note="SCF41.09, unknown, len: 334 aa. Similar to several FT hypotheticals including: Rhizobium sp. SW:Y4MH_RHISN (EMBL; FT AE000085) hypothetical 33.9 KD protein Y4MH (297 aa), fasta FT scores opt: 262 z-score: 309.5 E(): 6.9e-10 23.8% identity FT in 303 aa overlap" FT /db_xref="GOA:Q9RJW0" FT /db_xref="InterPro:IPR006992" FT /db_xref="UniProtKB/TrEMBL:Q9RJW0" FT /protein_id="CAB55712.1" FT /translation="MTVVDAHLHVWDPEQAAYEWLGPAMAPVDRAMRFHDALPALRTAG FT VGAAVLVQAADNDEDTDLMLATAARHPEVVGVVAWVPLDDPGRARARLAALRRDPHVVG FT VRTLLHERSDPDWVLGPDADAGLALLAEAGLPFDYSTTSPAALRHLAELSARHPALRLV FT VDHLGKPPVGGGREDRAEWHRLIAAAAKHPGVHAKLSGLYSASGALDAWTTDEVRPFVE FT DALELFGPERLMYGGDWPISLLAGGYARTWEAMCELLAPLAPDDRAAVLGGTATRFYRL FT DPALLNTAHHAAV" FT CDS 56683..58158 FT /transl_table=11 FT /gene="SCO0351" FT /gene_synonym="SCF41.10" FT /product="hypothetical protein SCF41.10" FT /note="SCF41.10, unknown, len: 491 aa." FT /db_xref="UniProtKB/TrEMBL:Q9RJV9" FT /protein_id="CAB55713.1" FT /translation="MIRSGRNANTMEHQTTTPDTAELAGWLHSWVTDEGAINGFHNHSV FT WGTNPATFLDFTSGHTTFAGPAVGAWARALAARPDERGVALLRRLLRYQCSEVQPDGQY FT AHIGFQVGESATSGLIHNAVGSLGMLLAVRHAGHLLPAEEVAAVLAAVRRNLDACEVYG FT GGRPGEEGTCNQEYARVWVKQLYTELSDDKTYAAEIPEDLAELIRLFHHRGVPDPESTG FT TFRTVRDRAEGGILEPAEYYGLMIVPLVLGHRAQGDPELLAEARRLCRHVARSAWTDES FT GATRYHRYWYVRGERALKTDTPMLIAGMGLTLYGIHEVLAEGPDAELEAFTEACLATYA FT RYQTPAGYFASASGWHNEADIAPSTAWHAHDLLFLMARYGPDEDFWDRVTAPRDRRSVL FT VSDRAYWAESGVHWSVRSPLTAGDLHLYGRKDRAVFAREFFAWTDREPLPEELRHPDVP FT EFFVADDGIYRVDHGEAPTDITAVGPLPYRGRL" FT CDS 58209..59477 FT /transl_table=11 FT /gene="SCO0352" FT /gene_synonym="SCF41.11" FT /product="putative solute-binding protein" FT /note="SCF41.11 possible solute-binding protein, len: 422 FT aa. Similar to many including: Streptomyces lividans FT TR:Q9Z492 (EMBL; AF043654) BxlE precursor (434 aa), fasta FT scores opt: 287 z-score: 311.3 E(): 5.5e-10 25.7% identity FT in 354 aa overlap. Contains a PS00013 Prokaryotic membrane FT lipoprotein lipid attachment site and a possible N-terminal FT signal sequence." FT /db_xref="GOA:Q9RJV8" FT /db_xref="HSSP:1MDP" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:Q9RJV8" FT /protein_id="CAB55714.1" FT /translation="MTSTNRGSKARGAALAAVVPLLLVAACSSGSGSAEGEDGEIRMMV FT NLTDNLNQAYWEKLVKPFEDETGLKVKIEGPTGKSVAESFPQQLAAGTAPDVIQSIFPD FT DDTAPELIDLGGEAWAKGTPMFDEYAMGDAHYAVGVGTQTQSLIYYNKTAFEKAGISGP FT PTTWDELTTDLGALEKAGYTPMQTAGDFQTGLQLQQIYHPTLNQLHPKWQTAVADDRLS FT VGDAYKPAFQMYADWIEAGYIGKSDVGLSPSQADGNFTAGKVGLYTNGSWFAASLDKAG FT DLPFEVGVFSPPAADGQAYPGPQGATMANPYMIRKGIGDEDGAKQLVEYLVTDAKAVEA FT QLGSDGVFRKGAESKQSGVDAQIQGILDDAPALVAVGEGQGNVRLPVTGFNPQFTEVAQ FT SLYTGAGPADAAKSIDQWVDENR" FT misc_feature 58257..58289 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS 59481..60392 FT /transl_table=11 FT /gene="SCO0353" FT /gene_synonym="SCF41.12" FT /product="putative binding protein dependent transport FT protein" FT /note="SCF41.12, possible binding-protein-dependent FT transport protein, len: 303 aa. Similar to many including: FT Streptomyces coelicolor TR:CAB41203 (EMBL; AL049661) FT putative binding protein dependent transport protein FT SCE134.05c (327 aa), fasta scores opt: 560 z-score: 661.2 FT E(): 1.8e-29 35.5% identity in 301 aa overlap. Contains a FT Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component. Contains multiple potential membrane-spanning FT hydrophobic domains." FT /db_xref="GOA:Q9RJV7" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9RJV7" FT /protein_id="CAB55715.1" FT /translation="MEQTSVSKPRAWRDLGARVSMVVPAVLVYVALLVVPVIYAIYYSF FT TEYNGFPHRVPEFIGLDNYRTMFGSDDITGTMVVTAVVAVVGAVAVNLAALGLALLLQR FT TNRFNTFGRVVMFYPHVLSALVVGFLWQAILGPQGVVNTMLEKAGTDSLPFLSDPDWAL FT WSMILVIVWSLFGVQLILYLAGLQAVPADLLEAARIDGASRWQTFRAVTWPSLASTVTV FT AVITSGISLLKTYDVVVSLTGGGPAGSTKTLAYSILAVSFPQRDIGVASAQAVLLIVAA FT AVLAITVLVLRRRAEDDAESIG" FT misc_feature 60033..60266 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 75.90, E-value 8.2e-19" FT CDS 60389..61231 FT /transl_table=11 FT /gene="SCO0354" FT /gene_synonym="SCF41.13" FT /product="putative binding-protein-dependent transport FT protein." FT /note="SCF41.13, possible binding-protein-dependent FT transport protein, len: 280 aa, Similar to many e.g. FT Streptomyces coelicolor TR:O50501 (EMBL; AL009199) probable FT transmembrane transport protein SC7b7.04 (302 aa), fasta FT scores opt: 584 z-score: 670.3 E(): 5.5e-30 36.1% identity FT in 274 aa overlap. Contains multiple membrane spanning FT hydrophobic domains, a PS00402 Binding-protein-dependent FT transport systems inner membrane comp sign and a Pfam match FT to entry PF00528 BPD_transp, Binding-protein-dependent FT transport systems inner membrane component." FT /db_xref="GOA:Q9RJV6" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9RJV6" FT /protein_id="CAB55716.1" FT /translation="MKKTLTSAATVRGAFVSLVSLGMLVPMYLLVVNAFKSQQEILANP FT FSPSFGTATFQYLADAWNNPDFSILKGYGVTIALVLCVNALAMAVCAPAAYVLARTPKP FT ISRLLLFFFIAGMFIPTQVILVPVIFVLRGIGLMGTLPGLILFMTATTIPFTLFVFFGY FT IRVLPRSLDEAAAIDGAGRYRTLWRIILPLMRPIVATVFILNSLSVWNDFASPQMILGP FT GSGVYTVTTGVYAAVGQYSTDYTKVFPTLLLAVIPILVIFVVMQRHIMSGLAAGAVKG" FT misc_feature 60875..61087 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 71.80, E-value 1.4e-17" FT misc_feature 60878..60964 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS 61305..61646 FT /transl_table=11 FT /gene="SCO0355" FT /gene_synonym="SCF41.14" FT /product="conserved hypothetical protein SCF41.14" FT /note="SCF41.14, unknown, len: 113 aa. Shares a low level FT of similarity with Bacillus subtilis TR:O05263 (EMBL; FT Z93938) hypothetical 12.6 KD protein (104 aa), fasta scores FT opt: 129 z-score: 179.4 E(): 0.012 31.3% identity in 96 FT aa overlap." FT /db_xref="GOA:Q9RJV5" FT /db_xref="InterPro:IPR008000" FT /db_xref="UniProtKB/TrEMBL:Q9RJV5" FT /protein_id="CAB55717.1" FT /translation="MPAPRTPRRVASVIRLRPEHAERYRELHRAVPGPVLDALSRAHVT FT NYSIFLRDHTLFAYFEYTGDDYEADMAAIAADPETQQWWTLTDPCQQPLDSAQPGERWV FT TGAELFPLY" FT CDS 61674..62465 FT /transl_table=11 FT /gene="SCO0356" FT /gene_synonym="SCF41.15" FT /product="probable oxidoreductase" FT /note="SCF41.15, probable oxidoreductase, len: 263 aa. FT Shares a high level of sequence similarity with Comamonas FT testosteroni TR:P94681 (EMBL:U32622) toluenesulfonate FT zinc-independent alcohol dehydrogenase (252 aa), fasta FT scores opt: 506 z-score: 549.4 E(): 3e-23 39.8% identity in FT 244 aa overlap and Streptomyces coelicolor TR:O88068 FT (EMBL:AL031541) putative dehydrogenase SCI35.33C (260 aa), FT fasta scores opt: 500 z-score: 542.8 E(): 7e-23 36.4% FT identity in 253 aa overlap. Contains a Pfam match to entry FT PF00106 adh_short, short chain dehydrogenase, Pfam match to FT entry PF00678 adh_short_C2, Short chain FT dehydrogenase/reductase C-terminus and a PS00061 FT Short-chain dehydrogenases/reductases family signature" FT /db_xref="GOA:Q9RJV4" FT /db_xref="HSSP:1Q7B" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RJV4" FT /protein_id="CAB55718.1" FT /translation="MPHTPTPPSPELAGLAAVVTGGASGIGLATARLLARRGARVAVLD FT LAPDAVPATDLEALLPVGCDVTDDASVRAGLDRAVDLLGGLDILVNNAGVGAQGTVADN FT DDAEWHRVLDVNVLGIVRTTRAALPHLRASRHAAVVNTCSVAATAGLPRRALYSASKGA FT VQSLTLAMAADHIREGIRVNCVNPGTADTPWIDRLLSSADDPAAERTALNARQPTGRLV FT SAEEVAAAIGYLASPAAASVTGTALAVDGGMQGLRLRPDGG" FT misc_feature 61716..62252 FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 225.30, E-value 8.7e-64" FT misc_feature 62103..62189 FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT misc_feature 62328..62420 FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 36.90, FT E-value 4.5e-07" FT CDS complement(62759..63478) FT /transl_table=11 FT /gene="SCO0357" FT /gene_synonym="SCF41.16c" FT /product="probable GntR-family regulator (putative secreted FT protein)" FT /note="SCF41.16c, probable GntR-family regulator (putative FT secreted protein), len: 270 aa. Similar to Streptomyces FT coelicolor TR:CAB50881 (EMBL; AL096844) putative FT GntR-family transcriptional regulator SCI28.07 (230 aa), FT fasta scores opt: 292 z-score: 343.8 E(): 8.5e-12 32.7% FT identity in 220 aa overlap and Escherichia coli FT SW:PDHR_ECOLI (EMBL; V01498) pyruvate dehydrogenase complex FT repressor(254 aa), fasta scores opt: 253 z-score: 298.6 FT E(): 2.8e-09 30.4% identity in 224 aa overlap. Contains a FT Pfam match to entry PF00392 gntR, Bacterial regulatory FT proteins, gntR family." FT /db_xref="GOA:Q9RJV3" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9RJV3" FT /protein_id="CAB55719.1" FT /translation="MSRPQRRRPPLAAAVVQSLATAIVLGQYPPGTALPSAGELCEEYE FT VSRTVIREATTTLAEKGLVATRQGWGTVVLGQDQWSLLDPLVLDALFQRADRLVYLDNL FT IEIRTTLECAMAARAAGRIDEEQSAALSAKLDELAGLIDDPEAYSRADIEFHEIIHHAS FT RDAFGRAIVSSIQGKAVRSPQYSGDPTREDIELTHQAHARVAAAVLDGDGDAAAEAMRE FT HITSSWARRRPADAPDA" FT misc_feature complement(63257..63436) FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 66.90, E-value FT 3.9e-19" FT CDS 63635..64777 FT /transl_table=11 FT /gene="SCO0358" FT /gene_synonym="SCF41.17" FT /product="possible racemase" FT /note="SCF41.17, possible racemase, len: 380 aa. FT Duplication of SCF41.06. Similar to Pseudomonas putida FT SW:MANR_PSEPU (EMBL; M19043) mandelate racemase (EC FT 5.1.2.2) (359 aa), fasta scores opt: 374 z-score: 431.2 FT E(): 1.2e-16 29.8% identity in 362 aa overlap. Contains a FT Pfam match to entry PF01188 MR_MLE, Mandelate racemase / FT muconate lactonizing enzyme family. This gene is duplicated FT on this cosmid and shares 74.3% identity, in 378 aa FT overlap, with the upstream gene, SCF41.06" FT /db_xref="GOA:Q9RJV2" FT /db_xref="HSSP:2MNR" FT /db_xref="InterPro:IPR001354" FT /db_xref="UniProtKB/TrEMBL:Q9RJV2" FT /protein_id="CAB55720.1" FT /translation="MRITGYRSLATVHEWGRPVGDVNGVVTTGVTEVPVLLLETDEGLT FT GVGLGGHADVERVFPALEGQDPRAVTSLYDRMLAHVFKSGHGGHVFATIGALDMALWDL FT KAKIAQEPLWRTLGAADRFVPGYASGLDYALSDDELVAFHGRWARRGFTGAKVKGGLDV FT DRDVRRLAAVRDVFRVNSERPALMYDVNECWGRHQAVRLARQVEERVELTWIEEPVRRW FT DVAGHRAVATGIRAAVATGENLTGLEHFRPLLAADAVGVVQTGAVWGITHFLRVSTLAF FT GHGLPVSPVGYNANPVAHAAAAVPNHLVTEVQDLAFPVGLRVDQEIADGGIVLGDAPGL FT GIEVDEERIVARAASGGWSLPSGPHVRPADAGLRLAPQAR" FT repeat_region 63636..64764 FT /note="This repeat unit is 76% identical to the repeated FT region 4874..5998." FT misc_feature 63650..64636 FT /note="Pfam match to entry PF01188 MR_MLE, Mandelate FT racemase / muconate lactonizing enzyme family, score 39.40, FT E-value 1.4e-10" FT CDS 64774..65496 FT /transl_table=11 FT /gene="SCO0359" FT /gene_synonym="SCF41.18" FT /product="conserved hypothetical protein" FT /note="SCF41.18, hypothetical protein, len: 240 aa; similar FT to TR:Q9KEZ0 (EMBL:AP001509) Bacillus halodurans BH0709 FT protein, 242 aa; fasta scores: opt: 515 Z-score: 603.7 E(): FT 5.4e-26; 36.000% identity in 225 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9RJV1" FT /protein_id="CAB55721.1" FT /translation="MRPHRGHVERAEGAWREQHMSMRKALVVRGGWEGHDPVGCTESVM FT PALERAGFEVEIAEDLAVYEDPGLLAATDLVVHSWSAGGLTADQEANLVDAVEAGTGFA FT GWHGGVVATNVANPRYLRMVGGRFLWHPDGFKEFTVRIRATPDRDGEIVEGVTDYDVQT FT EHYWVLTDSLNTVLATSVLTPGPADPWDEPVEFPVVWTRRWGAGRVFICTLGHRVADLR FT VPQTAAIVGRGLVWAARG" FT CDS complement(65559..66551) FT /transl_table=11 FT /gene="SCO0360" FT /gene_synonym="SCF41.19c" FT /product="probable DNA-binding, LacI family, regulator" FT /note="SCF41.19c, probable DNA-binding, LacI family, FT regulator. len: 330 aa. Similar to Escherichia coli FT SW:GNTR_ECOLI (EMBL:D84362) gluconate utilization system FT GNT-I transcriptional repressor (331 aa), fasta scores opt: FT 674 z-score: 767.8 E(): 0 36.9% identity in 320 aa overlap. FT Contains a PS00356 Bacterial regulatory proteins, lacI FT family signature, a PS00237 G-protein coupled receptors FT signature, Pfam match to entry PF00532 Peripla_BP_like, FT Periplasmic binding proteins and LacI family and a Pfam FT match to entry PF00356 lacI, Bacterial regulatory proteins, FT LacI family. Contains a possible helix-turn-helix motif FT between residues 2..23 score (+5.90 SD)." FT /db_xref="GOA:Q9RJV0" FT /db_xref="HSSP:1LCC" FT /db_xref="InterPro:IPR001761" FT /db_xref="UniProtKB/TrEMBL:Q9RJV0" FT /protein_id="CAB55722.1" FT /translation="MTLSDVAAAAGVSAQTVSRVVRDPLSVSDETRARVQAALTATGYV FT PNLAASNLASNRSRTVAALVPQINASVFADTVHAFSTALAAHGYQIFVGTTDYRPEHEE FT EVLRSFLGRRPDGLLMVGTRHTPGTLTLLRAAGVPVVETWGWSRDPVDLLVGFSNAAAA FT AAMVGHLVERGRRRITFAGRHTSGDPRAAERLDGYTGAVRDLLGGEARTVDAGPEPVTM FT DTGVALLDLALERYPDSDALMFSSDVFAAGALQACVRRGIDVPGRLAVAGFGDFELARH FT LVPALTTVAVPSARIGELGAELLLARMRGAAVDVPHRDVGHRVVAREST" FT misc_feature complement(65652..66383) FT /note="Pfam match to entry PF00532 Peripla_BP_like, FT Periplasmic binding proteins and LacI family., score 63.80, FT E-value 3.6e-15" FT misc_feature complement(66369..66419) FT /note="PS00237 G-protein coupled receptors signature" FT misc_feature complement(66474..66557) FT /note="Pfam match to entry PF00356 lacI, Bacterial FT regulatory proteins, lacI family, score 35.10, E-value FT 2e-08" FT misc_feature complement(66489..66545) FT /note="PS00356 Bacterial regulatory proteins, lacI family FT signature" FT CDS complement(66623..67795) FT /transl_table=11 FT /gene="SCO0361" FT /gene_synonym="SCF41.20c" FT /product="conserved hypothetical protein SCF41.20c" FT /note="SCF41.20c, unknown, len: 390 aa. Highly similar, FT over available sequence, to Caulobacter crescentus TR: FT Q46022 (EMBL; X98879) xylX gene (fragment) (>140 aa), FT fasta scores opt: 276 z-score: 326.5 E(): 7.8e-11 50.0% FT identity in 122 aa overlap." FT /db_xref="GOA:Q9RJU9" FT /db_xref="InterPro:IPR011234" FT /db_xref="UniProtKB/TrEMBL:Q9RJU9" FT /protein_id="CAB55723.1" FT /translation="MNQWPDAATTLPADGTGGALVGRVWRPGLGPSVVAVREDGLHDIT FT AAFPTVRDLCETPDPAARLRAARGERIAGLDEVLANTPVDTRDPRRPWLLAPVDLQAVK FT AAGVTFVVSMLERVIEERVRGDAAGAAEARERIRRLVGDDLAALRPGSEEAAALKELLV FT AQGAWSQYLEVGIGPDAEIFTKAPVLAAVGSGADAGVHAASRWNNPEPEVVLAVSSTGA FT VVGATLGNDVNLRDVEGRSALLLPQAKDNNASAALGPFLRLFEPGFRMDDVRRATVTLT FT VEGADGYRLDAESSMAAISRDPLDLVAQLLGPHHQYPDGAVLYLGTMFAPVEDRDVPGQ FT GFTHHDGDLVAVATPKLGTLANRIRPSDVCVPWTFGIADLMRALVARGAL" FT RBS 67926..67930 FT CDS 67935..69146 FT /transl_table=11 FT /gene="SCO0362" FT /gene_synonym="SCF41.21" FT /product="putative racemase" FT /note="SCF41.21, possible racemase, len: 403 aa. Weakly FT similar to Eukaryotic and Prokaryotic racemases e.g. Homo FT sapiens (Human) TR:O43673 (EMBL; AF047020) FT alpha-methylacyl-CoA racemase (EC 5.1.99.4) (382 aa), fasta FT scores opt: 466 z-score: 544.7 E(): 5.5e-23 31.1% identity FT in 392 aa overlap and Streptomyces coelicolor TR:CAB40680 FT (EMBL; AL049587) putative racemase SC5F2A.13 (398 aa), FT fasta scores opt: 508 z-score: 593.2 E(): 1.1e-25 34.5% FT identity in 383 aa overlap" FT /db_xref="GOA:Q9RJU8" FT /db_xref="HSSP:1PQY" FT /db_xref="InterPro:IPR003673" FT /db_xref="UniProtKB/TrEMBL:Q9RJU8" FT /protein_id="CAB55724.1" FT /translation="MASRDKPGVLAGYRVLDCSIAMAGPFAAQRLGDLGADVVKVEPVT FT GEWQRHAAAGGAGGNRINVSFLSLNRNKRSLAVDLKDPAGKEVLRRLVTTADVFLQNYR FT PGVADRLGVDYASLAAINPSLVYVSISGYGEDGPYARRPGQDLLLQAMSGAMLSSGRAG FT EAPRAAGQYLVDAVTASTAFEGVLAALLHRERTGEGQLVTVNMLDAVTTLQMQELSVHT FT VGGLPQTRSAEPHAHVYIRSPYGAFQTSDGYLVLAFPPLKRLGEILGEDTFLAMEDEEH FT GWTHRDEIFARTAARLLTRPSRHWLDAFAAAGIWAGPVYGYADLVQDPQIRHNGTFVTY FT EHPTEGSVTVPGFPYKFSATPPRIDRGAPLVGEHTREVLSEAGLTEGEIEELLAAGAVT FT ETAS" FT CDS 69143..70252 FT /transl_table=11 FT /gene="SCO0363" FT /gene_synonym="SCF41.22" FT /product="putative integral membrane protein" FT /note="SCF41.22, possible integral membrane protein, len: FT 369 aa. Contains possible membrane spanning hydrophobic FT domains." FT /db_xref="GOA:Q9RJU7" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:Q9RJU7" FT /protein_id="CAB55725.1" FT /translation="MTHIGAPYRGLTWDHPRGYDALAACAGGLVHWDVQPLEGFESHPV FT DELCARYDLVVLDHPHLGEAVVTGCLRPLDDLFTPAELARWGAGSIGPTMRSYAMDGRQ FT WALPLDAATQVAATRTDLVGEPPGTWDEVRRLARRAPVALSLAGPHAFLTFASVALAVG FT EEPAADPDQLIGDGTGLAVLDLLADLDALAPPGTRELNPIGLLELMAGTDRLAHCPLVY FT GYVTYADRLTFTDAPAVTAGGRPGSTLGGAGIALSARCVPSPELLAHMRWLMSPEAQGD FT FLPRHSGQPSARTAWTSPKTVAADFYRRTAATCEQAWVRPRHAGYIGFQTAASAAVRAA FT LAGETGHREALDRMRALYRTSRTAKEPQT" FT RBS 70236..70239 FT CDS 70249..71055 FT /transl_table=11 FT /gene="SCO0364" FT /gene_synonym="SCF41.23" FT /product="putative enoyl-CoA hydratase" FT /note="SCF41.23, possible enoyl-CoA hydratase, len: 268 aa. FT Shares a high level of similarity with Mycobacterium FT tuberculosis TR:O53418 (EMBL; AL021897) enoyl-CoA hydratase FT MTV017.23C (EMBL; AL021897), fasta scores opt: 554 FT z-score: 635.0 E(): 5.1e-28 40.9% identity in 257 aa FT overlap. Contains a Pfam match to entry PF00378 ECH, FT Enoyl-CoA hydratase/isomerase family" FT /db_xref="GOA:Q9RJU6" FT /db_xref="HSSP:2DUB" FT /db_xref="InterPro:IPR001753" FT /db_xref="UniProtKB/TrEMBL:Q9RJU6" FT /protein_id="CAB55726.1" FT /translation="MSDTGHLPPPDLGTDLVLLDVTDRVAILTLNRPAKLNAVTPGMSR FT ALVRAIEWCDTTDEVRALVVTGAGERSFSVGSDIGALDQYATPWDFRNRVDYCDAIRAA FT RTPTVAAVGGYALGGGLETALSCDIRLAADTASFGAPEITLGWIGGGGMTAFLSRAAGP FT GNAALMLLTGERIDAERALAWHLVSEVVPRAGLLDRARALAAVIASRAPVAAETAKINL FT RAAGNLPEDQALAYERDLQTICFATEDAAEGRRAFAEKRSPVFHKR" FT misc_feature 70324..70824 FT /note="Pfam match to entry PF00378 ECH, Enoyl-CoA FT hydratase/isomerase family, score 166.20, E-value 5.6e-46" FT CDS 71066..71812 FT /transl_table=11 FT /gene="SCO0365" FT /gene_synonym="SCF41.24" FT /product="probable oxidoreductase (putative secreted FT protein)" FT /note="SCF41.24, probable oxidoreductase (putative secreted FT protein), len: 248 aa. Similar to Rhizobium sp. (strain FT NGR234) SW:Y4LA_RHISN (EMBL; AE000082) putative short-chain FT type dehydrogenase/reductase Y4LA (EC 1.-.-.-), fasta FT scores opt: 487 z-score: 537.0 E(): 1.5e-22 38.8% identity FT in 245 aa overlap. Contains a Pfam match to entry PF00106 FT adh_short, short chain dehydrogenase, Pfam match to entry FT PF00678 adh_short_C2, Short chain dehydrogenase/reductase FT C-terminus and a PS00061 Short-chain FT dehydrogenases/reductases family signature" FT /db_xref="GOA:Q9RJU5" FT /db_xref="HSSP:1FJH" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RJU5" FT /protein_id="CAB55727.1" FT /translation="MKQPRAALVTGAGGALGRATAVRLAADGHDVAVLDRDAESLEHTA FT ALVEKAGARVLALGTDLRDAPAVAAAVERTVTDLGPLRVLVNNAAVYPSRAFLDVPLAE FT YEEVVAVNQRAYWVAAQAAARHMTGTGGGAIVNVASITLHGGWDSLAAYVSTKGAAVAL FT TRALARELGPAEIRVNCVSPGAFPTAAEEIHEDPDAYRRHVLDHQALKRRGRPEELASV FT VSFLTGPDASFVTGQCVEVNGGWVMA" FT misc_feature 71078..71632 FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 184.00, E-value 2.4e-51" FT misc_feature 71483..71569 FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT misc_feature 71696..71788 FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 43.80, FT E-value 3.9e-09" FT CDS 71809..72876 FT /transl_table=11 FT /gene="SCO0366" FT /gene_synonym="SCF41.25" FT /product="conserved hypothetical protein" FT /note="SCF41.25, hypothetical protein, len: 355 aa; similar FT to the plasmid borne TR:Q9R6D3 (EMBL:AB016260) FT Agrobacterium radiobacter TIORF127 protein, 361 aa; fasta FT scores: opt: 520 Z-score: 612.2 E(): 1.8e-26; 34.295% FT identity in 312 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9RJU4" FT /protein_id="CAB55728.1" FT /translation="MKLYGRSHDRQSLARHAGDLSAAGGVRAVVLDDGSERGIRTLEFR FT TGGGLSFDVLVDRAMDLGGAEFEGRGFGWRSATGFRHPGLHEYRDDDGLSMMRSFSGLL FT LTAGLDHTLFGAEVDASQYRYPPRGTAVHALHGRVANLPARLTGYGERWQEDGRCVLWA FT EGEVRQAAIFGEHLRLTRRIEADLGGSEIRLTDRVRNAGFDPTPHMYLYHVNVGWPFLD FT EGARYELPPHRTLWRSDSVAEQGVSHTAMPAPLPGFVEQVYEHELEPDAAGLARPRLVN FT ERLGVYFELEFDTVRFPSFFQWLHLREGAYAVGFEPSTHHVQGEAAAREDGSMTFLAPG FT EEREYTTAFRVGHLD" FT stem_loop 72896..72953 FT CDS complement(72921..73478) FT /transl_table=11 FT /gene="SCO0367" FT /gene_synonym="SCF41.26" FT /product="putative membrane protein" FT /note="SCF41.26, putative membrane protein, len: 185 aa. A FT low level of similarity to Streptomyces coelicolor FT TR:O54175 (EMBL; AL021411) hypothetical 24.6 KD protein FT SC7H1.16 (257 aa), fasta scores opt: 190 z-score: 226.1 FT E(): 3.1e-05 35.1% identity in 188 aa overlap. Contains FT possible hydrophobic membrane spanning regions" FT /db_xref="InterPro:IPR010699" FT /db_xref="UniProtKB/TrEMBL:Q9RJU3" FT /protein_id="CAB55729.1" FT /translation="MVTANSALTGVGLGGADPRLGALAAVAVVCYVLGAAGAGWAAGHA FT QRGGRLRPADFLLLELVLLWAVVAWWLAAGGDPTGGERTAMLGILAAAMGCQNAGVRVA FT MGAQVPTAYLTGLLTGAVTDAVTSGRVQWPALVTTALLILGAAAAALLERLLPGAAPLL FT PALLVTAAWLTGRARTGTRRAS" FT misc_feature 73932..73974 FT /note="22/27 bp inverted repeat bounding insertion element FT IS1649." FT misc_feature 73932..75001 FT /note="Insertion element IS1649." FT RBS 74034..74039 FT CDS 74045..75001 FT /transl_table=11 FT /gene="SCO0368" FT /gene_synonym="SCF41.27" FT /product="transposase" FT /note="SCF41.27, transposase, len: 318 aa. Almost identical FT to several Streptomyces coelicolor transposases: TR:O86758 FT (EMBL; AL031035) transposase SC6A9.26 (318 aa), fasta FT scores opt: 2214 z-score: 2579.1 E(): 0 99.7% identity in FT 318 aa overlap and TR:CAB52905 (EMBL; AL109949) putative FT insertion element transposase SCJ11.20 (318 aa), fasta FT scores opt: 2214 z-score: 2571.8 E():0 99.7% identity in FT 318 aa overlap. Contains a possible helix-turn-helix motif FT between residues 26..47 scores (+3.19 SD)." FT /db_xref="GOA:Q9RJU2" FT /db_xref="InterPro:IPR001584" FT /db_xref="UniProtKB/TrEMBL:Q9RJU2" FT /protein_id="CAB55730.1" FT /translation="MVHRNAPLTETGRLRLARCVVEDGWPVRRAAERFQVSHTTASRWA FT RRYRQLGVTGMSDRSSRPHHQPRRTAAAVEEHVLRLRREHRIGPLRLAVRCGIAASTAH FT RILVRHGLPPLAALDRATGEPVRRYERARPGELVHIDVKKLGRIPDGGGHKTLGRAEGH FT RSRTNGAGWAYLHTALDDHSRIAYTEDLPDETAPTCAAFLVRATAYFASLGIRIERVLT FT DNAWAYSKNTWRNTCRDLDISPRWTRPWRPQTNGKVERFHRTLLDEWAYQKPYTSDHER FT REAFTHWLHWYNYHRPHTGIGGHTPASRGTNLSEQHT" FT misc_feature complement(74959..75001) FT /note="22/27 bp inverted repeat bounding insertion element FT IS1649." FT CDS complement(74998..78255) FT /transl_table=11 FT /gene="SCO0369" FT /gene_synonym="SCF41.28c" FT /product="putative secreted protein" FT /note="SCF41.28c, putative secreted protein, len: 1085 aa. FT Contains a possible N-terminal signal peptide sequence" FT /db_xref="GOA:Q9RJU1" FT /db_xref="InterPro:IPR013737" FT /db_xref="UniProtKB/TrEMBL:Q9RJU1" FT /protein_id="CAB55731.1" FT /translation="MPRTNPPVRHRTAAALAGVTAFVTLLAGAVTADAATTGTITPTAL FT RTQHLTEALGIDDTTPDLSWQTTAGAPNTRQAAYRVQAATSLQRLRASRPDLWDSGKVE FT SSVPGTTYAGKDPGSRAKVYWRVMLWSGKGKRHSGWSTTAVFETGLTRQSDWDAQWITH FT PDWRLSDRTVEPVVVHLPRTTARYVRLDVTRLGLPLAESFPGRTWRLQVGEIDVRDSTT FT ATTGLARGAAVTASESNTVRKSWEPALAVDGLPNSALQTAAGYASAAHTGPDVSDAPIT FT LTLDLKSVKTFDEVALYPRADVLTDDGRIPGLPVDYTVSAADSADGPATRLAAVTGQRQ FT PTPYLPAGLPLLTDDFTLPKRVRSARLYIAGLGVYDATVNGEPVGDAVLEPANTDFAER FT VQYATYDVTDRLRTGANTLGVALGNGMSNVVSTADRYRKLYGNLSDPKLIARLEVTLAD FT GRVRTITSGDDWRTTLGPTTASNWYGGEDYDARREIPRWDEPAGDRRGWRHAVAVAGPG FT TADRPALLSARETEPIRVVETLKGKEVDGAEGSRVFDLGRNIAGWPEITVRAPEGTAIR FT VYPAESLKDGHAFQSISNVGAPLWDSYTTAGGWHAESWHPRFSYHGFRYLELRGVPENA FT TVSVRGHVLRTDNASAGDFTSSDPLINGIHSLIRRSIEGNMMSVLTDCPSREKLGWLEQ FT NQLVFPALAGNYDMRAYLRKIVRDMADAQTPDGLVPSTVPEYTSLPGAYRNDSNWGGAF FT VLVPWQLYLTYGDRQTLETYYPDMRRYAAFLEAQAADGILDYGLGDWFTPDRTFPRAVA FT GTYGYWRVVDTLGRIASLLGDTAAADEYRRKAAASVEALTAKYYDATTGTFGGGGHGAE FT ALALDMGAYPQGERDRLLSHFTDAIKDAGNHLVLGEISLPAAFRVLSAADRDDVVHAIA FT TQTTSPSYGYQVLAGNTTLGESWDGGPGQSQNHFMLGAIDSWFTTRVAGISQTEDSVGY FT AKLLVDPAVEGDMTSAAGSYRTPYGVARTDWERSDDRFRLTVDVPAGSTAEVHVPVAGE FT HAEAPGSARLLRLTGGEAVYEVGSGHWTFRSTMERGR" FT CDS complement(78286..81690) FT /transl_table=11 FT /gene="SCO0370" FT /gene_synonym="SCF41.29c" FT /product="possible DNA-binding protein (putative secreted FT protein)" FT /note="SCF41.29c, possible DNA-binding protein (putative FT secreted protein), len: 1134 aa. Contains a possible FT N-terminal signal peptide sequence and a possible FT helix-turn-helix motif between residues 51..72 scores FT (+3.60 SD)" FT /db_xref="GOA:Q9RJU0" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q9RJU0" FT /protein_id="CAB55732.1" FT /translation="MPEHPLSRRRFVAAAGATGALVAVGLPDAAHASGRPAGPAGPAGQ FT ERHAWSARHFADPRHDSRPTVYWYWNGPVTPELVDRQLADLRSKGMYEVILFSFDNAEM FT TPVFFTEEWFDIVGHVLRTAERTGMRVWLFNDDHFPSGRAGEFIVKGGQVGTRTYAPRP FT DLRLKALARSTTVVCGPASIDLRRSTGVGVDAGRLVADAAVLDGAAVLRDSAEWGDCTV FT TGSAKAEHGAAGLLVRGSADGRTGYAVSFDQTGVVTVERLTDGAEPAELLRSPRTDGFN FT KTKFHTLRITLGDGGLSVTLDGRDKGTVADLAEEAGGAGVRAVGDQRAVWESLTVEAAD FT GTTLYTGAFDRSAAAGDFPERALSTAGFTLAAAAARPTAATAATDVVDLTDRLTGGHTW FT HVPAGEWQVDLFGGVLLADDSQGYSRSYVDLLDDEPVELFLDIVPGEYHRRFGHYFGTV FT VPGFWDDEPFFASAEAHFKRLPWSPALDRALRTVGATPGTAYAAAFDDLGRSGRIARGN FT YWRAVSDRFATAFRKQAQWYEKRGVALITNPLYDETAPAKRIPSTGDLHKVNQWAQVPG FT GDIITAEYVAGEPTMIPRNPVSVAHQMGRERALLEMFGNMGWQVTPGFVHATVGAQAAR FT GVNLTVLHALWTDESRVYFPPPFGPRAPWWWAMRPLAEWIGRVMEAGRGTSAARTALLQ FT PQRAAEQWTGTDRQQDVDGPLSEAAYALERAQVDFDLLHEGALTRDPALLAHAEVRKGR FT LVVGAAAYDLVVIPRTPVLDADGVRVLREFVRTGGTVIAVGALDTEEADGGDRTLAHGL FT ADLFGNRTPARRPLGRGHAVRVADTGALGAVAVEAGTAAAVLEPPQDAVRVLRVRRGPD FT TVFLINNESGARVRTAAALPATGVPEIWDPATGTGGTAPVYRATKNGVRVPLDLEPFRT FT AVVVVRGGHRDRPHLTEATLPVLSVTRHGNALRATVEATAAGTHRLVGADGGHRYHGTV FT RIDDTLTPVPVDGDWTLTFEREGAEPVTAPLGSWTEHDALFSGSGTYTTDIDVDADRLR FT GRRVVLDLGDVRDVAEVSVNGTALPPLLWAPFAADVTGHVRAGRNTLRVRVANTLSNER FT KKPLPSGLLGPVTLRFRSRTTVELRRS" FT CDS complement(81751..84360) FT /transl_table=11 FT /gene="SCO0371" FT /gene_synonym="SCF41.30c" FT /product="putative secreted protein" FT /note="SCF41.30c, possible secreted protein, len: 900 aa. FT Shares a low level of similarity, over the available FT sequence, with Bacteroides ovatus TR:Q45327 (EMBL; U15179) FT arabinosidase (ASDII) (fragment) (>436 aa), fasta scores FT opt: 323 z-score: 317.9 E(): 2.4e-10 30.6% identity in 304 FT aa overlap. Contains a possible N-terminal signal FT sequence." FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q9RJT9" FT /protein_id="CAB55733.1" FT /translation="MPAPHSRPAPSRRQVLFTASAATAAAATPAAAAAAAPAGSAAATP FT PAHAGATPSPTNGAHRPGPLLEPFPLSAVRLLDSPFLANMRRTCAYLRFVDPDRLLHTF FT RLNVGLPSAAEPCGGWEAPDVQLRGHTTGHLLSALAQAHAGTGETAYADKARLLVSALA FT ECQRAAPAAGFHRGYLSAFPESVFDQLEAGGKPWAPYYTLHKIMAGLLDQYRLSGNREA FT FDVLLEMAAWTEARTAPLSRERMQSVLKVEFGGMNDVLARLHLETGDPVHLRTARRFDH FT DELYAPLAAGRDELAGRHANTEIAKVVGAVPAYEATGDRRYLDIADTFWTTVVRHHSYA FT IGGNSNQELFGPPDEIASRLSEVTCENCNSYNMLKLGRDLFRHDPERTEYLDHYEWTLY FT NQMLAEQDPDSAHGFVTYYTGLWAGSRREPKGGLGSAPGSYSGDYDNFSCDHGTGLETH FT TKFADTVYFRTPGTRRPALHVNLFVPSEVCWDDLGVTLRQDTDMPTGDRTRLTVTGGEA FT RFALRIRVAGWLAAGDGRAGLTVNGRRTGGRLEPGTYTTVTRHWRTGDRVELVLPRVPV FT WRPAPDNPQVKAVSYGPLVLAGAYGDTPLTTLPAVRPDTLRRTPGEPTRFTAVADGRRI FT PLRPFHEIHHQRYNVYWSVTPPSPTAGDVARYPLDEGHGTSVADRTGTFGDGSLAGGAT FT WSTGDDGTAVTLDGRDGHVVLPAGLPSGLAELTVSVRVRVDTLAPSVRVFDLGYSKDTY FT LFLTATTGAGRARAALKIAGMEAEDFVDATGPLPLGRWTHVALTLGAGTGVLYVDGVEA FT GRNTAMVSGPLLLGRTSRNYLGRSQNSTHPYLHGAVRDFRLHNRVLTADQVRRLAQG" FT CDS complement(84578..87592) FT /transl_table=11 FT /gene="SCO0372" FT /gene_synonym="SCF41.31c" FT /product="putative secreted protein" FT /note="SCF41.31c, possible secreted protein, len: 1024 aa. FT Contains a possible N-terminal signal sequence." FT /db_xref="InterPro:IPR017909" FT /db_xref="UniProtKB/TrEMBL:Q9RJT8" FT /protein_id="CAB55734.1" FT /translation="MHELVSQRGGMSRRAVLAAAVTAGVTATAVTASPGVAALPAGPAA FT DRAAGPARWFADPARSVRPKFRWWWPDGLVDPDEVAREIDQIADAGFGGAEIAAVHHSI FT RDKSLLDTAHHGWGSRPWRDGVEAALRRAVRRGLTVDLTLGPSWPVAVPGVTPDDEAAA FT QELAHGRTSLAAGATYRGPVPAPVHEAASGVRAQRLLAVQAARVDPANSTRKETGLDPD FT SVRDLTDTVTDGGLTWTAPADGEWMLISYWQRGSGQQPESGPHSAPGAFVVDHLSPAGT FT TAVTDYWERHVLTGSLRRLLKAAGGSFFEDSVELESEGLVWTARLPEVFEQRTGRPLLP FT WLPVLVLDDSNQVFAFGAQLTRQIRHDFWATVSDLFNRHHVGALKDWAHSLGMTLRAQP FT YGLQTDAVATAAILDIAEGESLGFKNLDDYRCLAGGRDMAGHTVLSCEAGAYNGSAYST FT TWDRVLRTMGGAYAAGVNQTVMHGFSYASAPEAEWPGFAAFSPYNGTPGYGESWGPRQP FT TWRHAEDIAGYLGRVHAVLQSGTARADVAVFRQTGYTATGIGASWFTSTGVPLGWTHQF FT LSGPLLDLPNATVLGGRLAPGGPAYKALFVEGDFFHGSTPTLALADARRILAFAEAGLP FT VVLLGGFDQALTPGVPEAGETERLRDVLTRLLALPGVVRVTEKTAVGDALAALGVTPDV FT RHSVPSTLLNAHRVTADADYYYLVNGKHAETVKPPVAAIDHDVTLRRTRGRDAVPYLLD FT PWTGRAARVGRYTLDGQDVTFRVALRPGQTLVVALGRPGLFGDRHGNRPHALSSDADEV FT LFTARGLTVRARAAGTYRTRLSQGRTVTTTLPAVPGPIEPGRWHVEVEDWRPGDRPTRT FT ERVRRTLTLDTLLPWSSIAELEDCAGIGRYRTTVTLPGDWGPTHGALLELGRVSDTFRV FT SVNGRDAEPADRLDPVVDVGPLLRRGTNTIEIEVATPLVNRLRVSRPEVFGGLARQEYG FT LVGPVRLVPYAQKTV" FT CDS complement(87761..88360) FT /transl_table=11 FT /gene="SCO0373" FT /gene_synonym="SCF41.32c" FT /product="putative secreted protein" FT /note="SCF41.32c, possible secreted protein, len: 199 aa. FT Contains a possible N-terminal signal sequence." FT /db_xref="UniProtKB/TrEMBL:Q9RJT7" FT /protein_id="CAB55735.1" FT /translation="MRRTTGATGGPIVSRPLLFLDVDGPLNPYAAKPQRRPAGYITLRV FT PRDGQTPDGHRSALVRRRPLRVWLHPRHGAELLRLDYELCWATTWMAEANRWIAPVIGL FT PELPFVDFGDVLLQDRPDGVHWKTAPLVEYANGRPFAWVDDEQGGLDQAYVTAHHRAPG FT LLHHVNPRIGLRDDDFRTLAEFARACTVPQRDRDGG" FT CDS 88750..90519 FT /transl_table=11 FT /gene="SCO0374" FT /gene_synonym="SCF41.33" FT /product="putative ABC transport protein" FT /note="SCF41.33, putative ABC transport protein, len: 589 FT aa. Similar to many e.g. Streptomyces coelicolor TR:Q9ZNB0 FT (EMBL; AB019513) ABC transporter (584 aa), fasta scores FT opt: 597 z-score: 649.7 E(): 7.7e-29 30.9% identity in 572 FT aa overlap. Contains a Pfam match to entry PF00005 FT ABC_tran, ABC transporter and a PS00017 ATP/GTP-binding FT site motif A (P-loop). Contains membrane-spanning FT hydrophobic domains." FT /db_xref="GOA:Q9RJT6" FT /db_xref="HSSP:1MT0" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9RJT6" FT /protein_id="CAB55736.1" FT /translation="MCAQIPAVLGRIARLSWRTDRRAVQLLLGCQVLTGLAAAVLLTAT FT AHAMNPVLGDGSAADRLHGALPALSVVALAAALGRGAAAVATYAERRITPRLTTETDSA FT LVEAVCRVEASAYAQEGFSDRHEAAEMGVVRTQVMVTDAQRFLSALIRMVTAGGVLSAL FT NPLMLPLLLLAVLPAGAGAVLTARVDYEVHYANIADRNVRGMMRWWATTSKYGDEVRAN FT SMTDYLVHWYRSLSDRCDRRTLSAAPRTLRIAVLSAAAGGVFLVATWGALAWLAVSGRI FT ELAVAATAVIAVQTTLAALSQVVVNGAAVFHTSLYLSDMQAFLDDAAARVPKRGPGKHR FT APTERIRLEEVVYQYPGKDRPAVDGVSLTLERGQILAIVGANGSGKSTLTRLLTGIYLP FT DKGRVTWNGTDLADMEPATVWAHIGLVPQIFAQWPMPVRENVTLGQPRGYDDTPVWEAV FT EAVGLREAVDNLPAGLDTLLSRDVFGGTELSGGQWQRVACARALYRRPGLLILDEPTSQ FT MDPRGEHQIFEQIKAIAAERITIVVTHRLENTRIADHIVVMEHGRITEQGRYDDLVHAG FT GTFAELLALSQDR" FT misc_feature 89866..90432 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 218.80, E-value 8.2e-62" FT misc_feature 89887..89910 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS complement(90531..92123) FT /transl_table=11 FT /gene="SCO0375" FT /gene_synonym="SCF62.01c" FT /gene_synonym="SCF41.34c" FT /product="putative integral membrane transport protein" FT /note="SCF62.01c, possible integral membrane transport FT protein, partial CDS, len: > 406 aa. Similar to many FT members of the drug resistance translocase family e.g. FT Staphylococcus aureus SW:QACA_STAAU (EMBL; X56628) FT antiseptic resistance protein (514 aa), fasta scores opt: FT 750 z-score: 750.4 E():0 30.0% identity in 493 aa overlap, FT as well as many other Streptomyces coelicolor membrane FT transport proteins e.g. TR:O54186 (EMBL; AL021411) SC7H1.27 FT (533 aa), fasta scores opt: 972 z-score: 970.2 E(): 0 FT 35.0% identity in 543 aa overlap. Overlaps with and extends FT into SCF41.34c. Contains multiple possible membrane FT spanning hydrophobic domains and a Pfam match to entry FT PF00083 sugar_tr, Sugar (and other) transporter." FT /note="SCF41.34c, possible transport protein, partial CDS, FT len: >157 aa. Similar to Streptomyces coelicolor putative FT transport protein TR:O54186 (EMBL; AL021411) putative FT transport protein SC7H1.27 (533 aa), fasta scores opt: 263 FT z-score: 281.1 E(): 2.6e-08 36.1% identity in 166 aa FT overlap." FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q8CK59" FT /protein_id="CAD55439.1" FT /translation="MSTSPPVRAPEAGGGSTPDARQLRTILIAVSVALMAVVASVSGLN FT VAQTHMAVEFGASQSTVLWIINIYTLALAALLLPLGAVGDRLGRRPMLVAGLGVFGAAS FT VLAGLAPSAEVMLAARVAGGAGAAMIMPVTLAVITSTFPEEQRGKAIGVWTGVAGGGGI FT LGMFLSALLVDVADWRLLFVLPVVLVLVALAMALKSVPDSRETAAHRFDTVGALISTVA FT VTGLIFVLQEGPERGWTDPVTLTGLVAGITAAVGFVAWELRRRDAALLDVRLFRERGLA FT GGSITLLVVFGVQAGIAVVLFPYFQAVLGWSGLLSTVALMPMAVMMMATSGLAPMLAAR FT VGSRATMAAGIALAGVGLALMALFVSVDDGYLTILPGMLAMGTGMGLSMTPSTEAITGS FT LPRGKQGVASALNDVTREFGTALGVALLGALLAGGYRAAIDGRLDGIPQGPADEARQGV FT ANAVEAAGGAGPHGPDLLHAAQQSFVDGWQQAMWAGVAVMGVLFVYVALRGPGRTAPAD FT ADEPEAAEALTAR" FT misc_feature complement(90924..92030) FT /note="Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter, score -87.50, E-value 0.00097" FT RBS complement(92128..92133) FT RBS 92222..92225 FT CDS 92232..92834 FT /transl_table=11 FT /gene="SCO0376" FT /gene_synonym="SCF62.02" FT /product="putative transcriptional regulator" FT /note="SCF62.02, possible transcriptional regulator, len: FT 200 aa. Similar to several proteins of undefined function FT from Streptomyces sp. e.g. Streptomyces coelicolor FT TR:CAB51134 (EMBL; Y18817) hypothetical 20.6 KD protein FT (190 aa), fasta scores opt: 352 z-score: 424.9 E(): 2.6e-16 FT 37.0% identity in 189 aa overlap. Contains a Pfam match to FT entry PF01381 HTH_3, Helix-turn-helix between residues FT 29..50 (+5.17 SD)." FT /db_xref="GOA:Q9RJL2" FT /db_xref="InterPro:IPR001387" FT /db_xref="UniProtKB/TrEMBL:Q9RJL2" FT /protein_id="CAB58317.1" FT /translation="MLLMTQEDGDLDSLVRKRIRALRVAQGWSLEELAGRARLSQSSLS FT RIENGRRRLALDQLVTLARALDTTLDQLVETADEDVITSPMIDSAHGLMRWPVKGDPGM FT TVVRQRMTQPPPENPARMRAHPGREWLVVLSGTAVLMLGHRRFRVETHQAAEFPTMMPH FT AIGTAGGPCEILGIFDRDARRGHQREGGEPEARDRAE" FT misc_feature 92286..92450 FT /note="Pfam match to entry PF01381 HTH_3, Helix-turn-helix, FT score 64.30, E-value 2.5e-15" FT CDS complement(92950..93483) FT /transl_table=11 FT /gene="SCO0377" FT /gene_synonym="SCF62.03c" FT /product="putative membrane protein" FT /note="SCF62.03c, possible integral membrane protein, len: FT 177 aa. Contains multiple possible membrane spanning FT hydrophobic domains." FT /db_xref="UniProtKB/TrEMBL:Q9RJL1" FT /protein_id="CAB58318.1" FT /translation="MPEGAGRGSAGGVAPRGILRRRPERWLFKGIYGLVLASALVAALD FT VPGEAANPGQDALWVLLTALTSGAAHGYAHVIAQRASGDGTAGPSRLRAVLAEWPLAVA FT VLPTVMMLLAAEAGWWAEETAADTALVLNTVLLFALGTSAARTAGLGRLSSCRAGALDM FT LIGLVIIAADALIE" FT CDS complement(93484..94218) FT /transl_table=11 FT /gene="SCO0378" FT /gene_synonym="SCF62.04c" FT /product="putative conserved secreted protein" FT /note="SCF62.04c, possible secreted protein, len: 244 aa. FT Highly similar to Streptomyces coelicolor TR:CAB52958 FT (EMBL; AL109950) hypothetical 25.2 KD protein SCJ4.24C (242 FT aa), fasta scores opt: 1283 z-score: 1457.6 E(): 0 83.1% FT identity in 242 aa overlap. Contains a possible N-terminal FT signal sequence." FT /db_xref="GOA:Q9RJL0" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RJL0" FT /protein_id="CAB58319.1" FT /translation="MRMKIAVIGGTGLIGSQVVKDLNAAGHQAVPHSRSTGVDVVGGGG FT VDDAVEGAEVVVNLTNSPTFDDASPAFFRASMDTLLAAARRAGTGHFVILSIVGVDRVP FT ALDYYRAKVLQEEILRDGPVPYSIVRATQFMEFMEAVLSWTASDDSVRLPATPIQPIAA FT KDVAAAVADVAVGAPLNGIRNIGGPEVFPLDELGRLTLAHKGDARTVVTDPGAGMFGAV FT EGDVLTDLDAHLAPTRYADWLS" FT RBS complement(94227..94231) FT RBS 94487..94491 FT CDS 94498..95961 FT /transl_table=11 FT /gene="SCO0379" FT /gene_synonym="katA" FT /product="catalase (EC 1.11.1.6)" FT /note="SCF62.05, katA, catalase (EC 1.11.1.6) len: 487 aa. FT Has been previously sequenced and characterised from FT Streptomyces coelicolor strain ATCC10147 TR:P77948 (EMBL; FT X96981) catalase (EC 1.11.1.6) (488 aa), fasta scores opt: FT 3300 z-score: 3768.6 E():0 98.2% identity in 488 aa FT overlap. Also similar to another proposed Streptomyces FT coelicolor catalase (EC 1.11.1.6) TR:Q9Z598 (EMBL; FT AL035478) SC2G5.25C (487 aa), fasta scores opt: 1704 FT z-score: 1896.1 E():0 53.8% identity in 483 aa overlap. FT Contains Prosite hits to PS00437 Catalase proximal FT heme-ligand signature and to PS00438 Catalase proximal FT active site signature. Also contains a Pfam match to entry FT PF00199 catalase, Catalase." FT /db_xref="GOA:Q9RJK9" FT /db_xref="HSSP:1M85" FT /db_xref="InterPro:IPR018028" FT /db_xref="UniProtKB/TrEMBL:Q9RJK9" FT /protein_id="CAB58320.1" FT /translation="MPENNQKPLTTVAGAPVPDNQNSLTSGPRGPMLLQDVWFLEKLAH FT FDREVIPERRMHAKGSGAFGTFTVTHDITRYTSAKIFSEIGKKTPLFTRFSTVAGERGA FT ADAERDIRGFAVKFYTDEGNWDLVGNNTPVFFFRDPLKFPDLNHAVKRDPRTNLRNAEN FT NWDFWTNLPEALHQVTIVMSDRGIPASYRHMHGFGSHTYSLINAEGERFWVKFHHRTQQ FT GIKNLTDAEAEALVGKDRESHQRDLFDAIEDGDFPKWKLFIQVMPEADAENYRFHPFDL FT TKVWSKKDYPLIEVGEWELNRNPDNYFADVEQAAFSPANVVPGISFSPDRMLQGRLFSY FT GDAQRYRLGVNHHQIPVNAPKNPVNSYHRDGAMRVDGNQGATPGVEPNSYGRWQEQPAY FT RDPAQAVGAVADRFNYREDDDNYFEQPGNLFRQMSPEQQQVLFENTARAIDGASAQTIE FT RHIGNCTQADPAYGAGVRKAIEALAAGNL" FT misc_feature 94525..95937 FT /note="Pfam match to entry PF00199 catalase, Catalase, FT score 1129.70, E-value 0" FT misc_feature 94633..94683 FT /note="PS00438 Catalase proximal active site signature" FT misc_feature 95503..95529 FT /note="PS00437 Catalase proximal heme-ligand signature" FT stem_loop 95997..96039 FT /note="Inverted repeat 21/21 (100%) with 1 base loop." FT RBS 96052..96055 FT CDS 96065..96460 FT /transl_table=11 FT /gene="SCO0380" FT /gene_synonym="SCF62.06" FT /product="conserved hypothetical protein SCF62.06" FT /note="SCF62.06, unknown, len: 131 aa. Weakly similar to FT several Prokaryotic Ank-like proteins e.g. Pseudomonas FT syringae TR:P95546 (EMBL; AF001355) AnkF precursor (183 FT aa), fasta scores opt: 255 z-score: 318.0 E(): 2.3e-10 FT 38.4% identity in 125 aa overlap. Contains 2x Pfam match to FT entry PF00023 ank, Ank repeat." FT /db_xref="InterPro:IPR002110" FT /db_xref="UniProtKB/TrEMBL:Q9RJK8" FT /protein_id="CAB58321.1" FT /translation="MDMHDSGGLTPEQTERVVAIAMDLAREGGTEQLVEFVQHGLPVDV FT RDPAGNSLLMLAAYHGHADTVRTLIRHGADPDLRNDRDQSPIAGALFKGADDVVAVLRQ FT AGADLDSGTPTARAAAAMFGREHLLAT" FT misc_feature 96209..96307 FT /note="Pfam match to entry PF00023 ank, Ank repeat, score FT 38.10, E-value 2e-07" FT misc_feature 96308..96406 FT /note="Pfam match to entry PF00023 ank, Ank repeat, score FT 6.10, E-value 13" FT CDS 96939..98414 FT /transl_table=11 FT /gene="SCO0381" FT /gene_synonym="SCF62.07" FT /product="putative glycosyl transferase" FT /note="SCF62.07, possible glycosyl transferase, len: 491 FT aa. Similar to many other glycosyl transferases e.g. FT Erwinia amylovora SW: AMSG_ERWAM (EMBL; X77921) FT UDP-galactose-lipid carrier transferase (EC 2.-.-.-) (477 FT aa), fasta scores opt: 599 z-score: 695.6 E(): 2.2e-31 FT 33.0% identity in 403 aa overlap. Contains multiple FT possible membrane spanning hydrophobic domains" FT /db_xref="GOA:Q9RJK7" FT /db_xref="InterPro:IPR003362" FT /db_xref="UniProtKB/TrEMBL:Q9RJK7" FT /protein_id="CAB58322.1" FT /translation="MRQGGLVSAFPSARGQLADGATSRLTSDWEQRYRRTVITSDTVTT FT AVVVAGIGNFFGVRDAANWHEKWGILAFGTWLLVLGALAVSRSWSPAVLGQGAEEFRRL FT GRSLFMATVVLALGGIALTSRNIKLWIFVAVPAIAIFIMVARYALRVRLHRQRKQGRCL FT RPVLAAGSPATVRDLIARTRRFPHLGWRVDAVCTTDDGLEGGQLDGVPVVGPLEHVAHH FT VRRDGYRVVAVTPDPHWSPHRLQRLAWNLEGSDAEMVVAPVLMEVAGPRLHVDAVLGIP FT LLRVSMPTFTGGRRAVKAVVDRLGAAVLLTLFAPLMLFVALLVLVDSRGGAFYRQRRVG FT KDGREFTILKFRTMVAGADGARAALADRNEGAGLLFKLRRDPRVTRVGAVLRRYSVDEL FT PQLLNVLAGSMSLVGPRPPLPEESAAYGPDIRRRLLVKPGLTGLWQISGRSDLPWEEAV FT RLDLRYVEDWSLALDTVILWKTLRAVVHGQGAY" FT RBS 98472..98476 FT misc_feature 98485..99747 FT /note="Pfam match to entry PF00984 UDPG_MGDP_dh, FT UDP-glucose/GDP-mannose dehydrogenase family, score 401.50, FT E-value 8.1e-117" FT CDS 98485..99810 FT /transl_table=11 FT /gene="SCO0382" FT /gene_synonym="SCF62.08" FT /product="UDP-glucose/GDP-mannose family dehydrogenase FT (putative secreted protein)" FT /note="SCF62.08, probable UDP-glucose/GDP-mannose family FT dehydrogenase (putative secreted protein), len: 441 aa. FT Highly similar to many e.g. Pseudomonas syringae (pv. FT phaseolicola) SW: ALGD_PSESH (EMBL; AF001555) GDP-mannose FT 6-dehydrogenase (EC 1.1.1.132) (438 aa), fasta scores opt: FT 1453 z-score: 1666.9 E(): 0 49.2% identity in 445 aa FT overlap. Contains a Pfam match to entry PF00984 FT UDPG_MGDP_dh, UDP-glucose/GDP-mannose dehydrogenase FT family." FT /db_xref="GOA:Q9RJK6" FT /db_xref="HSSP:1MFZ" FT /db_xref="InterPro:IPR017476" FT /db_xref="UniProtKB/TrEMBL:Q9RJK6" FT /protein_id="CAB58323.1" FT /translation="MRVSVFGLGYVGCVSAACLAGMGHQVVGVDVNQAKVDLVNDGKAP FT VVEERIGELIAEVVGSGALRATGDVREAIMESEISLVCVGTPSEPNGSLCTTYLERVTE FT EIGTALAERGGGGGRHTVVFRSTMLPGTCANLLVPILEKYVGGTAGVDFGVAVNPEFLR FT EGTSVRDFFDPPKTVIGELDAAGGDAVLALYDSLPGEVFRVPVATAEAIKYADNAFHGL FT KIGFANELGAVCHALGVDSHQVMDVFLADRKLNISPAYLRPGFAFGGSCLPKDLRSLVH FT AAQRADVSVPILSHVLPSNSAHLERAVELVERTGKRRVGMFGLSFKPGTDDLRESPLVE FT LAERLFGKGYDLRIHDANVSLSRLLGANREYVETRLPHLAQLLADSVDEVLDHAEVCLV FT GTRDPAVLSALPHGAGPLLIDLIHLPDADTRRTEPGYMGLAW" FT CDS 99881..101104 FT /transl_table=11 FT /gene="SCO0383" FT /gene_synonym="SCF62.09" FT /product="hypothetical protein SCF62.09" FT /note="SCF62.09, unknown, len: 407 aa. Weakly similar to a FT number of glycosyl transferases e.g. Streptomyces FT coelicolor TR:CAB39859 (EMBL; AL049497) putative glycosyl FT transferase SC6G10.05C (412 aa), fasta scores opt: 236 FT z-score: 280.6 E(): 2.8e-08 26.4% identity in 386 aa FT overlap and Escherichia coli TR:Q47594 (EMBL; D43637) FT mannosyltransferase B (381 aa), fasta scores opt: 187 FT z-score: 223.4 E(): 4.3e-05 23.3% identity in 288 aa FT overlap. Contains a TTA leucine codon, possible target for FT bldA regulation." FT /db_xref="GOA:Q9RJK5" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q9RJK5" FT /protein_id="CAB58324.1" FT /translation="MENLSVPFDRRVWQEATTLRDAGWDVHVICPRGSKRDTEPEAVVD FT RVHIHRYPLRAATGGPAGYLREYGAALWHTARLARRVGPVDVVHACNPPDLLFLPALWL FT KRRGARFVFDQHDLIPELYLSRFGRGKDLLYRAVCALERWTYRAADVVLATNESYKDVA FT IRRGGRRPDDVFVVRSAPATDRFQPVPPEPELKRGKPHLLCYLGVMGPQDGVDYALRAL FT AKLRDEVGRTDWHAVFVGSGDAFDAMVELSRSLGLDEQVRFTGRIPDADLVRHLSTADV FT CLSPDPRNPLNDVSTMNKVLEYMAMGRPIVSFDLREARVSAGEAALYAPANDEAAFARL FT VARLLDDPDERARMGKIGQERVTGRLSWRNSQAALLAAYAAACRDHTPVSAGAPVRTGF FT KAGKRPRS" FT misc_feature 100910..100912 FT /note="TTA/leucine codon, possible target for bldA FT regulation" FT CDS 101179..102468 FT /transl_table=11 FT /gene="SCO0384" FT /gene_synonym="SCF62.10" FT /product="putative membrane protein" FT /note="SCF62.10, possible membrane protein, len: 429 aa. FT Contains a possible membrane spanning hydrophobic domain FT and a probable coiled-coil from 146 to 176 (31 residues)." FT /db_xref="GOA:Q9RJK4" FT /db_xref="InterPro:IPR002328" FT /db_xref="UniProtKB/TrEMBL:Q9RJK4" FT /protein_id="CAB58325.1" FT /translation="MVGALAGYGVSVLFPPRYTASASVLLPGQWEQRELVTQVEIATSS FT AVVDRAADELRWNGVGRSELRDRVSAETADGNIVKISGTAATPERAQRLSDEVAQQFVT FT YAARIASGTTGADEAAGPEALREQVTRTNRRITDLANAADPGQTVESVQARTELEKLRS FT ALQDAMQKLEEADPANNRAGMVVMGPAARPAGEAPPTRLQLIGGGALLFFVLAVIAHLT FT AARVNRRPRSESEIAAALGTALLGTVDVPGDRRAHRPKARGAQARFRRLLGVDVRWDLP FT TPRSSGDEAGRRLRYRRVRARLRERVPTARRLLVVVPDDDEVARRAAGRLAADAEDDPR FT LRVVEVSVARPIVPDRDTESGALVVLSAGARTAEELAGVAEACADGGHEVVGVVVAGAV FT RARPTASADEPRGDAAAGAAVHDHATGGVA" FT RBS 102453..102460 FT CDS 102465..104030 FT /transl_table=11 FT /gene="SCO0385" FT /gene_synonym="SCF62.11" FT /product="putative membrane protein" FT /note="SCF62.11, possible membrane protein, len: 521 aa. FT Contains possible membrane spanning hydrophobic domains and FT two possible coiled-coils from 144 to 182 (39 residues) FT and from 190 to 221 (32 residues)." FT /db_xref="GOA:Q9RJK3" FT /db_xref="InterPro:IPR000169" FT /db_xref="UniProtKB/TrEMBL:Q9RJK3" FT /protein_id="CAB58326.1" FT /translation="MTTTDTASQPSASAPLLDLQALVVAVRRRRRLWGSLALLGLLLGA FT AVAVLLPPRPTAVTKVLVAHKDDQPNDTGTLIRTDVELLDTTRIAAAALRTLGSRENPE FT DFMRDYRGTGLTNNLLRIDVTADSDAEAVARAKALADTFVADHVRRMREAAEAESKSLL FT DQRDRMRKELAEVNSAIGDRSPDDEPKASASIESLFARRAELDSRIAEFDQRAAEALTG FT TPEVVAGTQIVDAPHAVEHSLPRAVGTDAAIGLALGLVLGLALSAVGAVVADRPVLRRE FT IAANLGASVLAELRRRPRRSARSWRRRRTRAARERLTTTLTRLVRGSAEPVSMLELGCA FT RGTGLIALDVAGALEADGPVVVVDGLPGTRLAGAHRGPGGPTVLSGERATAEGHQGRRL FT GVGSVAPGTAWTDLRYLGSRTVLVVRAGHGSTAWLHTVARQLADQRIAVIGVVLIDPDP FT RDRTDGTLWDGPHLARRVPGERPKRHNGGGTPHAVQAVGEGRLRAERPSMPAATVPDSD FT QEAR" FT RBS 104017..104022 FT CDS 104034..105968 FT /transl_table=11 FT /gene="SCO0386" FT /gene_synonym="SCF62.12" FT /product="putative asparagine synthetase" FT /note="SCF62.12, putative asparagine synthetase, len: 644 FT aa. Highly similar to many e.g. Mycobacterium tuberculosis FT SW:ASNH_MYCTU (EMBL; Z70283) putative asparagine synthetase FT (glutamine-hydrolysing) (EC 6.3.5.4) (652 aa), fasta scores FT opt: 752 z-score: 874.8 E():0 32.8% identity in 655 aa FT overlap. Contains a Pfam match to entry PF00310 GATase_2, FT Glutamine amidotransferases class-II." FT /db_xref="GOA:Q9RJK2" FT /db_xref="HSSP:1CT9" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/TrEMBL:Q9RJK2" FT /protein_id="CAB58327.1" FT /translation="MCGIAGTYHWPDGKAVTDRLTDVLAHRGPDGAGRYSHPAGEGEVH FT LGHRRLAVVDLSTTGAQPMVSEGLALSYNGELYNAPELRTELESAGVRFRGTSDTEVVL FT EAWRRWGTDCLPQLRGMFAFAVFDERTGELVLARDQLGIKPLFLLRRGAGLVFASELKA FT LATATGGKLEVDHAALVASLLYYWVPDSRCALREAEKLPPGSWLRCRPDGRVERGRFWN FT LRDVAAEGRERARSGERPDLAAVVEESTRRHLLSDVPVATFLSGGLDSSYLTALAARDR FT PGISAYTIGFRAEDARFEAMPDDLRYARQVAERFGVDLHEIEIAPNVLDLLPRMTYHLD FT EPIGDPAAINTFLICSAAREAGVKVMLSGMGADELFAGYRKHLANVLALRYQRVPRPLR FT RGVSAAVGRLPVASSRRGYRSVRFAKRFLSFADLPQETAFRRSYTMYDRQELLDLIDPD FT LAGTVEDVLTEHADVYEDNDLDDFVNRMCLADARMFLPGLNLAYTDRSSMAASTEVRVP FT YVDVEVVKAAFAVPGDRKIVGRQGKAVLKEAATSVLPREIVYRPKGLFSAPLRAWMSRD FT LAPLVREVVNDGELVRSGFLRRDALRRLVAEDAAGQRDFSKHLWHVLTLEYWYRGATSG FT SGDHSSSTA" FT misc_feature 104037..104480 FT /note="Pfam match to entry PF00310 GATase_2, Glutamine FT amidotransferases class-II, score 87.90, E-value 2.4e-29" FT RBS 106048..106051 FT CDS 106070..108250 FT /transl_table=11 FT /gene="SCO0387" FT /gene_synonym="SCF62.13" FT /product="putative bi-domain oxidoreductase" FT /note="SCF62.13. possible bi-domain oxidoreductase, len: FT 726 aa. The N-terminus is similar to many Zinc-binding FT dehydrogenases e.g. Sinorhizobium meliloti TR:O31186 (EMBL; FT AF031940) alcohol dehydrogenase (340 aa), fasta scores pt: FT 224 z-score: 241.8 E(): 4.1e-06 25.5% identity in 333 aa FT overlap. The C-terminus is similar to other oxidoreductases FT e.g. Zymomonas mobilis SW:GFO_ZYMMO (EMBL; M97379) FT glucose-fructose oxidoreductase precursor (EC 1.1.99.28) FT (439 aa), fasta scores opt: 243 z-score: 260.3 E(): FT 3.8e-07 26.1% identity in 272 aa overlap. Note this CDS is FT also weakly similar to the C-terminus of the Eukaryotic: FT Cochliobolus heterostrophus TR:Q92217 (EMBL; U68040) FT polyketide synthase (2530 aa), fasta scores opt: 164 FT z-score:0.0 E(): 0.0 25.52% identity in 576 aa overlap. FT Contains a Pfam match to entry PF00107 adh_zinc, FT Zinc-binding dehydrogenases and a Pfam match to entry FT PF01408 GFO_IDH_MocA, Oxidoreductase family. Also contains FT possible membrane spanning hydrophobic domains" FT /db_xref="GOA:Q9RJK1" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RJK1" FT /protein_id="CAB58328.1" FT /translation="MQNYKSGELALLDVPVPGCKPGGVLVRTAYSLISTGTELMKVSEA FT GMSMLGKARSRPDQVAKVVQSVATNGVPATYRKVMGKLDSYTPLGYSLCGVVEQVGEGI FT DDVKAGDLVACAGNEHALHAELNWVPRNLYAPVPDGLAARDAAFGTVGSIALQGVRQGE FT SRLGETALVIGLGLIGQLVVQLLVASGVRVVGADPDAERCELAERLGAAACGDPASPAV FT ESAVVELTDGHGVDQVYLAAGGGSNQPVELAARLCRDRGRVVDIGKCRLDLPWNAYYEK FT ELDVRFSRSYGPGRYDPEYELEGRDYPIGYVRWTERRNLACFLDLVARGRVDVAPLITR FT TADFDDAVETYRSLQDGALKAVAVLFRYPGQPDAEAPAGAPAVTVPGVRRGAGAAAPAR FT AARTPVRLAFVGAGNYATSMLLPHLARREGVELSTVVTTTALSAANAQRKFGFGEATTD FT LDAVLGDASVDAVFVVTRHSSHAELTRKALLAGKAVFVEKPLALTGEELTGVLAAVEES FT GNDRVQVGFNRRFAPLLQEARKRFGARTGPASLRYLVNAGRLDHGSWYLQQGTEGSRFA FT GEGGHFVDTASWLLGADPVSVYALAPSSNEDLQVVLGYPDGSTATLSYVTTGAAGFPKE FT TLDLVADGKVLQLDDFVRSSVYDGRKRWVSSRLPKARDKGQSAELAAFVRAVRTGGPMP FT VPLESLVATTAATLAVRTALAAGAPVGLAEAR" FT misc_feature 106076..107167 FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score -34.50, E-value 6.5e-08" FT misc_feature 107282..107995 FT /note="Pfam match to entry PF01408 GFO_IDH_MocA, FT Oxidoreductase family, score 121.00, E-value 2.2e-32" FT RBS 108238..108242 FT CDS 108253..110214 FT /transl_table=11 FT /gene="SCO0388" FT /gene_synonym="SCF62.14" FT /product="hypothetical protein SCF62.14" FT /note="SCF62.14, unknown, len: 653 aa. Weakly similar to FT Cytophaga heparina TR: Q59289 (EMBL; U27586) heparinase III FT protein precursor (EC 4.2.2.8) (659 aa), fasta scores opt: FT 202 z-score: 229.2 E(): 2.1e-05 22.8% identity in 421 aa FT overlap." FT /db_xref="InterPro:IPR012480" FT /db_xref="UniProtKB/TrEMBL:Q9RJK0" FT /protein_id="CAB58329.1" FT /translation="MTPGSAGWYLRRLSRMGPREVAGRVGDTVRRRRWRSVRPDAPGVS FT GARFTAVLPAGTIAAVPPDAAKRLVAEADRLLAGHVEYFGVRRDDLVEPDWCFDPKTGR FT RAPWGYAFDVPYRDEDAVGDIKQIWEPSRHQYLTVLAAAYAVTGDERYAERVAEHLRSW FT WAANAPLRGVHWVSGIELGIRLLSWVWIRRLLDGWPGAAALFEDNPAALEQIWHHQRWL FT AAFPSRGSSANNHVVAEAAGQLAAACAFGWFPESARWRDDALRSLERHLRGNTFLSGLN FT RELATEYHGLVLELGLAAVAEADAAGVPVPATVRLVLLRMTDALAAVVDDRLRPPRQGD FT ADDGHGLVVDGAGTDRWGSLLATGDAVFGSLPWWPTVTGTDVRTPLLAALVRPYGGDGA FT GRAVTRPARRPAHFADAGLTVLRGPGGIWCRCDGGPHGFLSIAAHAHADALSVEVRHDG FT VDVLADPGTYCYHGQPVWRGYFRSTLGHNTLELDGADQSVSGGPFLWTRHARTRVLAVD FT TSDEKVSRWCAEHDGYGDSVHRRRVELTAASRELRVVDEVRGPRRSVRLAFHLGPAVAA FT DLAGSRAALTWTRDGEERSAVLDLPGALSWRAHRGETDPPLGWYSPGFGRKEPATTLVG FT TGVTDGAQEFTTVLGFRG" FT RBS 110221..110227 FT CDS 110237..111772 FT /transl_table=11 FT /gene="SCO0389" FT /gene_synonym="SCF62.15" FT /product="putative lipoprotein" FT /note="SCF62.15, possible lipoprotein, len: 511 aa. FT Contains a possible N-terminal signal sequence and an FT appropriately positioned Prosite hit to PS00013 Prokaryotic FT membrane lipoprotein lipid attachment site." FT /db_xref="InterPro:IPR006626" FT /db_xref="UniProtKB/TrEMBL:Q9RJJ9" FT /protein_id="CAB58330.1" FT /translation="MGSRRRGGTWSAAASLALALLAAGCTGTPDAKAPEPTAPSSPSGA FT RKVARVCEKPAAGPAKAPAGAVTVDPAVVGDLADKTRNSPANTTFWLRPGKHRLASDRY FT SQVVPKEGNRYLGAPGAVLDGRKTNQYAFGGTARDVTIGHLTVQGFVAPHDEGVVNHDS FT ADGWVIEHATIRRNSGAGLMAGDRQQVRASCLRDNGQYGINAYKGDGVINDLVLEGNEI FT TGNNTGDWERRRPGCGCTGGVKFWAVQGADVRGNWVHHNRGTGLWADTNNNDFLIEDNV FT LEGNDGAALIYETSYNAVVRENTIRRNNWVEGRENTDGGDDFPYATVYISESGGEPRVE FT ARTDKIEIYRNVLEDNWSGITLWENADRFCNSPANTSSGDCTLLVEDVDRCARPAIASA FT PLYADCRWKTQRVDVHDNRFTLDKSVVECTDGCDRMALLANYGTYPDWSPYRGERVAEA FT VTLRQHNRWHDNVYVGPWKFVAHDPSRVLDFGQWRGAPYRQDADSTLRPGGGD" FT misc_feature 110279..110311 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS 111774..113006 FT /transl_table=11 FT /gene="SCO0390" FT /gene_synonym="SCF62.16" FT /product="putative membrane protein" FT /note="SCF62.16, possible membrane protein, len: 410 aa. FT Contains a possible N-terminal signal sequence and multiple FT possible membrane spanning hydrophobic domains." FT /db_xref="UniProtKB/TrEMBL:Q9RJJ8" FT /protein_id="CAB58331.1" FT /translation="METGRTPKLVGTVWGLLILNTLGSTGAETVVPLPRSLIQMVTMGA FT LAVAFSLALALNLRLRVRASAFLFLLTLLLVPSVISSADLESGFGALFRCARLGLFVGT FT LWLLSRWWDGSPTFVRHHIRMYFAVLCTVAAGALVSPGAAMPDLYGGRLVGALWPLTPP FT QIGQYAAVIIGLALLLVLSRQTDRRSAALVIVPSLLLLVLTHTRTATLGLLVGLTLAIG FT SLALTSAAARRFFSWAVLCAAVAAVAFASALHAWFLRGQSEENFSNLTGRAKVWDALLA FT APRTVGEKVFGIGLGDKSFDGLPIDNSWLAVYHEQGLIGIALVATVFVVLGGVALLRPP FT SPARACAIFLISYCALASYTEAGLGDASPYLLHLAVAASLLASPAAATPRVTPEPPRRR FT VPRWARTPEVT" FT RBS 112994..113001 FT CDS 113009..114250 FT /transl_table=11 FT /gene="SCO0391" FT /gene_synonym="SCF62.17" FT /product="putative transferase" FT /note="SCF62.17, possible transferase, len: 413 aa. Similar FT to many including Streptomyces coelicolor TR:Q9Z5B7 FT (EMBL:AL035478) putative transferase SC2G5.06 (406 aa), FT fasta scores opt: 263 z-score: 301.1 E(): 2.1e-09 31.9% FT identity in 385 aa overlap and Erwinia amylovora FT SW:AMSK_ERWAM (EMBL:X77921) amylovoran biosynthesis protein FT AmsK (407 aa), fasta scores opt: 224 z-score: 257.0 E(): FT 5.8e-07 28.4% identity in 232 aa overlap. Contains a Pfam FT match to entry PF00534 Glycos_transf_1, Glycosyl FT transferases group 1" FT /db_xref="GOA:Q9RJJ7" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q9RJJ7" FT /protein_id="CAB58332.1" FT /translation="MHVLVVHNRYNSAQPSGENNVVDQEVALLRAAGHRVGLFERRSDD FT IASRSLLGKVAVPLLVPWNPAVRRELADRLRTERPDVVHVHNVFPLLSPAVLAACADAG FT VPAVATLHNYTQVCPPGTLQRDGRPCTECVGAAPLPAVRHGCYRNSRLATVPLAVGLSV FT NRRRWWSGVERFFCISAAQREVLVGAGLPAERLAVKHNFVPDPEARRAGPGEHLLYLGR FT LAEAKGVRLLMEAWDELAADGGVGVPLVVAGTGPLEREVTAWAAGRDDVRYVGLYDPEQ FT CRRALARSVAVVAPSTWLEAFGLVVVEAMAAGVPAVAAGHGAFAELVDDGVTGLLHRPG FT EAASLASRIRRIAAEPEGNQEMGRAARRRYEQGFSPAVGLERLLEGYRTAIAGRSALAR FT DGDVRAGRGDGGSR" FT misc_feature 113657..114115 FT /note="Pfam match to entry PF00534 Glycos_transf_1, FT Glycosyl transferases group 1, score 71.40, E-value FT 2.6e-19" FT CDS 114247..115497 FT /transl_table=11 FT /gene="SCO0392" FT /gene_synonym="SCF62.18" FT /product="putative methyltransferase" FT /note="SCF62.18, possible methyltransferase, len: 416 aa. FT Similar to several including: Streptomyces peucetius FT TR:O68501 (EMBL; AF048833) daunorubicin/doxorubicin FT biosynthesis enzyme DnrX (403 aa), fasta scores opt: 801 FT z-score: 923.6 E(): 0; 36.7% identity in 403 aa overlap and FT Streptomyces fradiae TR:AAD41823 (EMBL:AF147704) NDP-hexose FT 3-C-methyltransferase TYLCIII (418 aa), fasta scores opt: FT 688 z-score: 793.6 E(): 0; 34.1% identity in 425 aa FT overlap" FT /db_xref="GOA:Q9RJJ6" FT /db_xref="InterPro:IPR013630" FT /db_xref="UniProtKB/TrEMBL:Q9RJJ6" FT /protein_id="CAB58333.1" FT /translation="MTRCRLCGSAAMESVVDLGATPPCESFLAADQLDRPEPAYPLHLR FT VCTDCWLAQIPALITPEETFTQYAYFSSYSSSWVEHARTFVTGAVERLGLGPGSFVVEV FT ASNDGYLLRHMVDRGIRCLGVEPSVNVGAAAREAGVPTLTEFLSPDTGAAVSAEHGPAD FT LVVANNVYAHIPDVVGFTQGLRALVADDGWVSIEVQHLLTLIEENQYDTIYHEHFQYYT FT VASAIRALASGGLALVDVELLPTHGGSIRLWARPAEVAGEPSRRVSDVLDREKAAGLRE FT LSGYTEFSSRVAKVRRDLLRFLIDAAERGDTVVGYGAPGKGNTLLNHCGVRPDLLAYTV FT DRNPYKHGRFTPGTRIPILSPERIAADRPDYVLVLPWNLREELVEQLSFVHEWGGRLVF FT PIPELSVVEAASEKGTA" FT CDS 115494..116303 FT /transl_table=11 FT /gene="SCO0393" FT /gene_synonym="SCF62.19" FT /product="putative transferase" FT /note="SCF62.19, possible transferase, len: 269 aa. Similar FT to many transferases e.g. Streptomyces glaucescens FT TR:Q54266 (EMBL:X82177) alpha-D-glucose-1-phosphate FT cytidylyl-transferase StrQ (fragment) (299 aa), fasta FT scores opt: 554 z-score: 687.3 E(): 6.3e-31 35.0% identity FT in 280 aa overlap." FT /db_xref="GOA:Q9RJJ5" FT /db_xref="InterPro:IPR013446" FT /db_xref="UniProtKB/TrEMBL:Q9RJJ5" FT /protein_id="CAB58334.1" FT /translation="MKVVLFCGGYGMRMREGALDDVPKPMAMVGPRPLIWHVMRYYAHF FT GHKEFILCLGYGAHHIKDFFLNYEETTSNDFVLRGGRTELLSADIADWTITFAQTGIES FT PIGERLRRVRHHLDGDEMFLANYADVLTDAPLPEMIDSFARRDAGASMMVVPPQSSFHC FT VDLGEDGLVGGITAVSDLPLWENGGYFVLRQEVFDHIPENGDLVADGCTQLAKRGRLVA FT HQHRGFWKPTDTVKERAALDAAYARGERPWAVWERDGAMSGAGVRTA" FT RBS 116291..116294 FT CDS 116300..116947 FT /transl_table=11 FT /gene="SCO0394" FT /gene_synonym="SCF62.20" FT /product="hypothetical protein SCF62.20" FT /note="SCF62.20, unknown, len: 215 aa" FT /db_xref="InterPro:IPR003737" FT /db_xref="UniProtKB/TrEMBL:Q9RJJ4" FT /protein_id="CAB58335.1" FT /translation="MIRLGAGSPERIVAVGAHCDDIAIGAGGTLLTVCLARPGVRVDAL FT VLSGGGGEREREERAALAAFCPGADLRLTVLKLPDGRMPAHWEEAKAAVEELRERTEPE FT LVLSPRTDDAHQDHRGLAKLMTTAFRDHLVLRYEIVKWDGDLGRPTAYQPLSEDVAEEK FT VRLLQEHYPSQRHRPWYDREAFLGLARIRGIECHARYAEAFDVAKLTLNLGG" FT CDS 116951..117976 FT /transl_table=11 FT /gene="SCO0395" FT /gene_synonym="SCF62.21" FT /product="putative epimerase/dehydratase" FT /note="SCF62.21, possible epimerase/dehydratase, len: 314 FT aa. Highly similar to Streptomyces glaucescens TR:Q54262 FT (EMBL:X78974) putative protein involved in biosynthesis of FT 5'-hydroxystreptomycin StrP (358 aa), fasta scores opt: FT 1446 z-score: 1656.6 E(): 0 68.4% identity in 342 aa FT overlap. Also similar to Streptomyces griseus SW:STRE_STRGR FT (EMBL:X62567) DTDP-glucose 4,6-dehydratase (EC 4.2.1.46) FT (328 aa), fasta scores opt: 260 z-score: 303.2 E(): 1.6e-09 FT 28.4% identity in 317 aa overlap. Contains a Pfam match to FT entry PF01370 Epimerase, NAD dependent FT epimerase/dehydratase family" FT /db_xref="GOA:Q9RJJ3" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RJJ3" FT /protein_id="CAB58336.1" FT /translation="MRVLLTGHQGYLGTVMAPVLTAAGHEVVGLDSGLFADCVLGPAPD FT DPPGQRVDLRDLTAEHVAGVDAVIHLAALSNDPLGSLAPELTYDINHHASVRLARLARD FT AGVQRFLYASTCSVYGAAGGGDLVTEDAPLRPVTPYAESKVRVEDDLHALSDGDFSPVY FT MRNATAFGFSPRLRADIVLNNLVGHALLSGEVLVLSDGTPWRPLVHAADIARAFAAALV FT APREAVHDRAFNIGSEVNNVTVAEIAEEVAAAVSGSKVVITGETGADPRSYRVDFSRFR FT AAIPGFDCEWTVKQGALELAEAYRKHGLTREDFEQRFTRLAVLRAAAGTGSVDDTLRWR FT R" FT misc_feature 116957..117874 FT /note="Pfam match to entry PF01370 Epimerase, NAD dependent FT epimerase/dehydratase family, score 2.10, E-value 2.2e-12" FT CDS 117973..119247 FT /transl_table=11 FT /gene="SCO0396" FT /gene_synonym="SCF62.22" FT /product="hypothetical protein SCF62.22" FT /note="SCF62.22, unknown, len: 424 aa" FT /db_xref="InterPro:IPR019232" FT /db_xref="UniProtKB/TrEMBL:Q9RJJ2" FT /protein_id="CAB58337.1" FT /translation="MTQAGGEMYALVERLYPLCRSITGDGVRATLDIVDEYIPLHMHEV FT PTGTQVLDWTVPQEWNIRDAYVADATGRRVVDFAASSLHVLGYSVPVSATMPLAELRPH FT LHTLPDHPAWVPYRTSYYRPQWGFCLAQETLDALPEGDYEVRIDSTLADGHLTYAEHVV FT QGQVSDEVIVSCHVCHPSLANDNLAGIAVATFLARELAERNPYYTYRFVFAPGTIGAIT FT WLARNRERVERVKHGLVLACAGDPGQVTYKQSRRGDAEIDRVLRHVLTDSERPHRVVEF FT TPYGYDERQYCSPGFDLGVGSLTRTPYAGYPEYHTSADNLDFVSPAAMADTLAVCREAF FT SVLDRNRRYVNLSPYGEPQLGRRGLYDSLGGRSDAKQAQMAMLWVLSLSDGEHSLLDVA FT EQSGLPFETVVEAADALHGAGLVKA" FT CDS 119253..120542 FT /transl_table=11 FT /gene="SCO0397" FT /gene_synonym="SCF62.23" FT /product="putative integral membrane protein" FT /note="SCF62.23, possible integral membrane protein, FT len:429 aa. Weakly similar to several proteins of undefined FT function e.g. Synechocystis sp. (strain PCC 6803) TR:P72591 FT (EMBL; D90899) iron(III) dicitrate transport system FT permease protein FecD (349 aa), fasta scores opt: 154 FT z-score: 170.4 E(): 0.039 25.4% identity in 334 aa overlap. FT Contains multiple possible membrane spanning hydrophobic FT domains." FT /db_xref="UniProtKB/TrEMBL:Q9RJJ1" FT /protein_id="CAB58338.1" FT /translation="MTVEGEKTTTPAEPARRGVVGRLSWGLADQAASSLSNFVVGIYVA FT RSLGLTAFGVFSLAWVTYGVVLNVSRGLATDPLVVRFSGVPESSWRGAVARASGAALLV FT GAGIGTVSLVAGLAIGGQVGAAFAALGVVLPGLLLQDAWRYSFFAAGVGRKAFVNDVVW FT AVALVPAMVVAARAGSVPAFLLAWGGSAAVAGVYGWFQSGIRPRPAGAREWHRDHRDLG FT YRYLVENVGVSGAGQIRAYGLGAIVGVGAVGVIRGAELLLGPFLAVLMGLSLVTVAEAA FT RVLRQAPRRLGKFCFLLGAGQTVAALLWGAALLLVPDRLGELVLGDVWSGASELIVPVT FT LSVAGAGLGTGAAAGLRALAAARRSLRCQLFASACYVAGGLGGAVAGGTVGSAWGAAAA FT SVCGSVVWWLQLRAALRERDHHSIPEVRTT" FT RBS 120531..120534 FT CDS 120539..121486 FT /transl_table=11 FT /gene="SCO0398" FT /gene_synonym="SCF62.24" FT /product="putative glycosyl transferase" FT /note="SCF62.24, possible glycosyl transferase, len: 315 FT aa. Similar to several e.g. Rickettsia prowazekii TR:Q9ZD96 FT (EMBL:AJ235271) glycosyl transferase (280 aa), fasta scores FT opt: 272 z-score: 326.2 E(): 8.1e-11 29.9% identity in 214 FT aa overlap and Neisseria gonorrhoeae TR:Q50949 FT (EMBL:U14554) glycosyl transferase (337 aa), fasta scores FT opt: 234 z-score: 280.4 E(): 2.9e-08 27.8% identity in 248 FT aa overlap. Contains a Pfam match to entry PF00535 FT Glycos_transf_2, Glycosyl transferases" FT /db_xref="GOA:Q9RJJ0" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q9RJJ0" FT /protein_id="CAB58339.1" FT /translation="MTPHPRLSIGLPVYNGEEYLAESLDALLGQTYENFELVISDNAST FT DGTRDICRRYAAQDSRIRYIRLPRNIGAAPNHNYVFTECRGELFKWASHDDLYARDLLR FT SCVAALDERPEVVLAHAGQAVIDGDGKVKVPYEYGLATDSPRAPERFRSLLFEPGGDDF FT YGVMRSAMLRRVKPHDSYHHADRTFVAEITLHGPFHQVPELLYFRRDHPTRAERANPSK FT RSRCVNLDPRRAGPLHPTPRLLAEYVWGFASAIGRAPLSSADRRACHRHLAAWLTSRVR FT PGVGERVEDRAPVDPDRLTVSVDDLVAGREGRQA" FT misc_feature 120560..121084 FT /note="Pfam match to entry PF00535 Glycos_transf_2, FT Glycosyl transferases, score 57.20, E-value 3.5e-13" FT CDS 121492..122715 FT /transl_table=11 FT /gene="SCO0399" FT /gene_synonym="SCF62.25" FT /product="putative membrane protein" FT /note="SCF62.25, possible membrane protein, len: 407 aa. FT Weakly similar to a several e.g. Erwinia amylovora SW: FT AMSJ_ERWAM (EMBL; X77921) amylovoran biosynthesis protein FT AmsJ (415 aa), fasta scores opt: 107 z-score: 129.1 E(): FT 7.8 21.3% identity in 423 aa overlap and Escherichia coli FT SW:WCAK_ECOLI (EMBL; U38473) colanic acid biosynthesis FT protein WcaK (426 aa), fasta scores opt: 111 z-score: FT 133.6 E():4.3 20.1% identity in 398 aa overlap. Contains a FT possible N-terminal signal sequence and a membrane spanning FT hydrophobic domain. Also contains a TTA leucine codon, FT possible target for bldA regulation and a Prosite hit to FT PS00017 ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q9RJI9" FT /db_xref="InterPro:IPR007345" FT /db_xref="UniProtKB/TrEMBL:Q9RJI9" FT /protein_id="CAB58340.1" FT /translation="MREKPLRIGVFGLFGAGNSGNDGSLEAVLDHLRAAHPDAVVDAMC FT GGPETVATRYGVPATRLNWYRGEYRTASRASAIAAKALGKLVDVFRTAAWVRRHDAVIV FT PGTGVLETTLPLRPWGFPYSLFLLCLTGRLFGTRVALVSVGAGAIGVRPTRVLTRWSTR FT LAAYRSYRDDQSRDAMRAMGVNTARDEVYADLVFALPGPSASEPVETRGPVCVGVMDFH FT GSNDERDVAEEIHRRYLDGTTRFVRALVEEGRPVRLLTGDELDRPVAAAIVDAVGSPLV FT TVAEAASLADLMKETASADTVVATRYHNLVCALKVGTPTLALSYSGKSDALMAEMGMGA FT YCHPAREADADRLLEQFRELERRSGPVRRTLCERNLVVARRVEDQFAALTTALFPATDH FT AHALREAP" FT misc_feature 121507..121509 FT /note="TTA/leucine codon, possible target for bldA FT regulation" FT misc_feature 122455..122478 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 122703..122707 FT CDS 122712..123263 FT /transl_table=11 FT /gene="SCO0400" FT /gene_synonym="SCF62.26" FT /product="putative epimerase" FT /note="SCF62.26, possible epimerase, len: 178 aa. Similar FT to many including: Streptomyces griseus SW:STRM_STRGR FT (EMBL; X62567) dTDP-4-dehydrorhamnose 3,5-epimerase (EC FT 5.1.3.13) (DTDP-4-keto-6-deoxyglucose 3,5-epimerase) FT (DTDP-l-rhamnose synthetase) (200 aa), fasta scores opt: FT 340 z-score:0.0 E(): 0.0 37.78% identity in 180 aa overlap FT and Leptospira borgpetersenii TR:Q9ZGK0 (EMBL; AF078135) FT RmlC (186 aa), fasta scores pt: 432 z-score: 524.9 E(): FT 7.2e-22 42.3% identity in 175 aa overlap. Contains a Pfam FT match to entry PF00908 dTDP_sugar_isom, FT dTDP-4-dehydrorhamnose 3,5-epimerase." FT /db_xref="GOA:Q9RJI8" FT /db_xref="HSSP:1EP0" FT /db_xref="InterPro:IPR014710" FT /db_xref="UniProtKB/TrEMBL:Q9RJI8" FT /protein_id="CAB58341.1" FT /translation="MKATEVPEISGAYLFRPTPHADARGFFCRTFDADVVRSVGLDPAA FT FVQDSVSRSVRGVLRGLHLRSGAGEAKLVRCSNGRIFDAVVDLRADSPTYLGRAFFELS FT GETQTTLYIPAGCAHGFQSLTETSDVSYRIDRAHDPAEDVTIAFDDPDLAIDWPLPVAS FT VSPRDREAPSLADFLKHREG" FT misc_feature 122733..123242 FT /note="Pfam match to entry PF00908 dTDP_sugar_isom, FT dTDP-4-dehydrorhamnose 3,5-epimerase, score 207.70, E-value FT 1.8e-58" FT RBS 123254..123258 FT CDS 123271..124596 FT /transl_table=11 FT /gene="SCO0401" FT /gene_synonym="SCF62.27" FT /product="putative aminotransferase" FT /note="SCF62.27, possible aminotransferase, len: 441 aa. FT Similar to many including Pseudomonas aeruginosa FT SW:GSA_PSEAE (EMBL:X82072) glutamate-1-semialdehyde FT 2,1-aminomutase (EC 5.4.3.8) (glutamate-1-semialdehyde FT aminotransferase) (427 aa), fasta scores opt: 475 z-score: FT 540.8 E(): 9.5e-23 34.8% identity in 434 aa overlap and FT Streptomyces coelicolor TR:CAB39702 (EMBL: AL049485) FT probable aminotransferase SC6A5.18 (461 aa), fasta scores FT opt: 464 z-score: 527.9 E(): 4.9e-22 32.4% identity in 407 FT aa overlap. Contains 2x Pfam matches to entry PF00202 FT aminotran_3, Aminotransferases class-III FT pyridoxal-phosphate" FT /db_xref="GOA:Q9RJI7" FT /db_xref="HSSP:1QJ3" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:Q9RJI7" FT /protein_id="CAB59810.1" FT /translation="MNAEELGLPRSRQANERLHALVPGGAHTYAKGDDQYPENLAPVIS FT HGRGAHVWDVDGNRYVEYGSGLRSVSLGHAHPRVTEAVRRELDRGSNFVRPSIVEVDAA FT ERFLATVPTAEMVKFAKNGSDATTAAVRLARAATGRPRVAVCADHPFFSVDDWFIGTTP FT MSAGIPAATNELTVAFPYGDLAATEDLLARHEGEVACLILEPATHTEPPPGYLAGLREL FT ADRHGCVLVFDEMITGFRWSEAGAQGLYGVVPDLSTFGKALGNGFAVAALAGRRELMEL FT GGLRHSGDRVFLLSTTHGAETHALAAAMAVQGTYVEEGVTARLHALGDRLAAGVREAAA FT SMGVGDHVVVRGRASNLVFATLDENGQPSQRYRTLFLRQLLAGGVLAPSFVVSSALGDA FT DLDHTVDVVAEACAVYRKALDAADPTPWMAGRPVKPVFRRLV" FT RBS 123355..123369 FT misc_feature 123415..123714 FT /note="Pfam match to entry PF00202 aminotran_3, FT Aminotransferases class-III pyridoxal-phosphate, score FT 61.30, E-value 9.5e-21" FT misc_feature 123808..124290 FT /note="Pfam match to entry PF00202 aminotran_3, FT Aminotransferases class-III pyridoxal-phosphate, score FT 80.10, E-value 2.8e-27" FT CDS complement(124654..125406) FT /transl_table=11 FT /gene="SCO0402" FT /gene_synonym="SCF51.01c" FT /gene_synonym="SCF62.28c" FT /product="putative integral membrane protein" FT /note="SCF51.01c, unknown, len: >48 aa" FT /note="SCF62.28c, possible integral membrane protein, FT partial CDS, len: >248 aa. Weakly similar in parts to FT Streptomyces coelicolor TR:O86624 (EMBL: AL031155) putative FT integral membrane protein SC3A7.23C (272 aa), fasta scores FT opt: 189 z-score: 228.1 E(): 2.5e-05 31.6% identity in 190 FT aa overlap. Contains multiple possible membrane spanning FT hydrophobic domains." FT /db_xref="GOA:Q8CK58" FT /db_xref="InterPro:IPR000326" FT /db_xref="UniProtKB/TrEMBL:Q8CK58" FT /protein_id="CAD55440.1" FT /translation="MTGRPGPAVLPSWLRVWFVLMACLAAPVVLVLGAVYADESEPREW FT DMRIFAAVDGVGPPWRHVAVVTDFLGEPAGAVLLVAAVVTGCLLLRHPRAAVFVVTGAG FT LTVGTTTLLKPVVGRTIHGDNLSYPSGHTAFLTAIALMVSLLAAGRLGLGRAAGTAFVF FT AAGLVAGAAMGWAQVALGSHYATDTLGGWCTALAVLPVTAWLVDRTADRLTDRWAGLPA FT HPPDEWTAGPPCDRRAERRADAGRQQGS" FT CDS complement(125609..126226) FT /transl_table=11 FT /gene="SCO0403" FT /gene_synonym="SCF51.02c" FT /product="hypothetical protein" FT /note="SCF51.02c, hypothetical protein, len: 187 aa; FT similar to various hypothetical proteins, e.g. TR:CAB56690 FT (EMBL:AL121596) Streptomyces coelicolor SCF51A.38 FT hypothetical 18.5 KD protein, 169 aa; fasta scores: opt: FT 176 z-score: 225.6 E(): 3.4e-05; 32.9% identity in 173 aa FT overlap" FT /db_xref="InterPro:IPR010852" FT /db_xref="UniProtKB/TrEMBL:Q9RJT3" FT /protein_id="CAB59700.1" FT /translation="MTTGPTLPILAVTGQDGDVDFAFVSGNPALDLTGTVLSRRDEPVD FT LLAVPADLGRWVAACEGLPDRVTATPSAFDAALNLREAVYRLALDRVLDRRFHIPSLEV FT VNAAAAGPLPTVRLGDAGVRMSGGLPAVLTHVARSGIAVLADPGARLKECGRTDCTRVY FT LDRSRGARRAWCGMEECGNRVKAAAYRARRRTSAAPSGRAER" FT RBS 126232..126235 FT CDS 126243..126983 FT /transl_table=11 FT /gene="SCO0404" FT /gene_synonym="SCF51.03" FT /product="putative 2-haloalkanoic acid dehalogenase" FT /note="SCF51.03, possible 2-haloalkanoic acid dehalogenase, FT len: 246 aa; similar to SW:HAD2_PSEPU (EMBL:D17523) FT Pseudomonas putida 2-haloalkanoic acid dehalogenase H-109 FT (EC 3.8.1.2) (L-2-haloacid dehalogenase H-109) FT (halocarboxylic acid halidohydrolase H-109) DehH109, 224 FT aa: fasta scores: opt: 275 z-score: 328.4 E(): 6.4e-11; FT 32.2% identity in 202 aa overlap. Contains a Pfam match to FT entry PF00702 hydrolase, haloacid dehalogenase-like FT hydrolase" FT /db_xref="GOA:Q9RJT2" FT /db_xref="HSSP:1QQ5" FT /db_xref="InterPro:IPR005833" FT /db_xref="UniProtKB/TrEMBL:Q9RJT2" FT /protein_id="CAB59701.1" FT /translation="MVASGRESAEEGVRAGMAGGILGIEVVVFDVLGTLVDEPGGLRAG FT IREAVPAADDAFVDELLALWQGHVEREQRRVVRGRRAYADSGIIDAEAARLVADRAGVG FT DPAAVDRLAGAGRRLPPWSDSAAGLDRLTRRLVVLGLSNASHTAVPRIAAYAGLRWHGA FT LSGETVRAYKPAPEVYRLAVDTAGCPPDRVLMVAAHAWDLRGARAGGMRTAYVRRPGGD FT PPTGSDDFDGRFEALDELADALRL" FT misc_feature 126312..126899 FT /note="Pfam match to entry PF00702 Hydrolase, haloacid FT dehalogenase-like hydrolase, score 27.80, E-value 2.7e-05" FT CDS complement(127015..127833) FT /transl_table=11 FT /gene="SCO0405" FT /gene_synonym="SCF51.04c" FT /product="conserved hypothetical protein SCF51.04" FT /note="SCF51.04, conserved hypothetical protein, len: 272 FT aa; similar to TR:O86540 (EMBL:AL031350) Streptomyces FT coelicolor hypothetical 32.8 kD protein, 300 aa; fasta FT scores: opt: 656 z-score: 793.0 E(): 0; 43.1% identity in FT 246 aa overlap" FT /db_xref="InterPro:IPR006764" FT /db_xref="UniProtKB/TrEMBL:Q9RJT1" FT /protein_id="CAB59702.1" FT /translation="MTGESSSIDSTRPTIARVYDYLLGGKDNYAADREIGDVFKRDLPG FT SVAIAFANRAALTRAVGEIVTRTGVRQFIDLGSGLPTADNVHQVAQRRAPETRVVYVDT FT DPQVLVHGRALLEENDRTRFVPVDVRDPEGIRSHPDTRQLIDFDRPVAVMFSAILHHVN FT DDEDPAAIVRYWRGQVPSGSLFFVSHFRSGNNPETVEAEKVLQETFGRGRWRTDAEIEA FT LLDGLEILEPGIVPASLWRPGTTAGTYDDGGERELTVWERLIAAGMARKP" FT RBS complement(127843..127847) FT CDS 127893..128606 FT /transl_table=11 FT /gene="SCO0406" FT /gene_synonym="SCF51.05" FT /product="hypothetical protein SCF51.05" FT /note="SCF51.05, unknown, len: 237 aa" FT /db_xref="GOA:Q9RJT0" FT /db_xref="InterPro:IPR011989" FT /db_xref="UniProtKB/TrEMBL:Q9RJT0" FT /protein_id="CAB59703.1" FT /translation="MTRSSLAAQEVVPMTMTRQDTDALGAFESLADPSASVRLRAALAV FT GTAPHPRFVEGLVERSAVEPEFFVRDMLTWALTRHPVAATLPPLVREVGSKLPQARSQA FT LHTLSKIGDRRAWPAVTGAALSDADDEVARSAWRAAVVLVPEGEEQALARALAPQLGRG FT DRETQLSLSRALVALGESAGAVLEAAATTAPAPHVRAHALATRRLLRDPDSGFEAAIEE FT AKRVVALGGSGHEGP" FT misc_feature 128610..128675 FT /note="Helix-turn-helix from SCF51.06 score 1170" FT CDS 128610..129614 FT /transl_table=11 FT /gene="SCO0407" FT /gene_synonym="SCF51.06" FT /product="putative transcriptional regulator" FT /note="SCF51.06, possible transcriptional regulator, len: FT 334 aa; similar to SW:TIPA_STRLI (EMBL:S64314) Streptomyces FT lividans transcriptional activator TipA, 253 aa; fasta FT scores: opt: 215 z-score: 237.9 E(): 7e-06; 37.9% identity FT in 103 aa overlap and to TR:O54191 (EMBL:AL021411) FT Streptomyces coelicolor putative transcriptional regulator FT SC7H1.32c, len: 196 aa; fasta scores: opt: 264 z-score: FT 290.9 E(): 7.8e-09; 37.4% identity in 139 aa overlap. FT Contains a Pfam match to entry PF00376 merR, Bacterial FT regulatory proteins, merR family and a prosite match to FT entry PS00552 Bacterial regulatory proteins, merR family FT signature. Contains possible helix-turn-helix motif between FT residues 3351..3416, score 1170 (+3.17 SD)" FT /db_xref="GOA:Q9RJS9" FT /db_xref="HSSP:1JBG" FT /db_xref="InterPro:IPR000551" FT /db_xref="UniProtKB/TrEMBL:Q9RJS9" FT /protein_id="CAB59704.1" FT /translation="MLIGEVARRSGVSARMLRHYESLGLVRPSGRTGSGYREYSRADIR FT RIFHIESLRSLGLSLREIGRALDEPGFAPAALVDDLIRRTRERIAAETELLTRLRRIDA FT AGPAGWEDVLQAVALLQALGSKSADARQRAALSSVQDASVPVEALVDAVLSETDTNVAG FT ALRWALARSGDDAAALLARGLDSPVAEVRARAVRALAELSGVEATARLRHALDGPDAVV FT RGYAALALGSRGAGEAVPTLVDMIVAGRNDTDAADALSVLASDPATADRIAAGLVGRLC FT DGTTDAAARGRLTQALAGIPGTRASSALAELSRDEERAVALTATYLLRLREEP" FT misc_feature 128619..128687 FT /note="PS00552 Bacterial regulatory proteins, merR family FT signature" FT misc_feature 128619..128726 FT /note="Pfam match to entry PF00376 merR, Bacterial FT regulatory proteins, merR family, score 44.50, E-value FT 2.3e-09" FT CDS 129615..130403 FT /transl_table=11 FT /gene="SCO0408" FT /gene_synonym="SCF51.07" FT /product="probable methyltransferase" FT /note="SCF51.07, probable methyltransferase, len: 262 aa; FT some similarity to TR:Q9ZGH6 (EMBL:AF079762) Streptomyces FT venezuelae N,N-dimethyltransferase DesVI 273 aa; fasta FT scores: opt: 165 z-score: 205.9 E(): 0.00043; 28.3% FT identity in 237 aa overlap and to TR:CAB49808 FT (EMBL:AJ248285) Pyrococcus abyssi menaquinone biosynthesis FT methyltransferase, 248 aa; fasta scores: opt: 165 z-score: FT 205.6 E(): 0.00044; 27.3% identity in 183 aa overlap" FT /db_xref="GOA:Q9RJS8" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:Q9RJS8" FT /protein_id="CAB59705.1" FT /translation="MLRQFASRRATWPTVTSSQLWTRETADRYDAEEAESGMGSAAVLG FT PTVDFLAELAGEGRALEFAIGTGRVGVPLRERGVPVAGIELSEHMAAVLRRKAAEETLP FT VTLGDMATTVVPGEFTLVYLVYNTITNLLTQDEQVECFRNAARHLGPGGRFVIELGVPP FT LRFLPPGQVAVPFDVSERHLGFDTFDLVEQILVSNHFTRDPGDGSYRRDNSRHRYAWPA FT ELDLMARIAGLELERRVADWDGAPFTADSAKHISVWRKPA" FT CDS complement(130492..130956) FT /transl_table=11 FT /gene="SCO0409" FT /gene_synonym="sapA" FT /gene_synonym="SCF51.08c" FT /product="spore-associated protein precursor" FT /note="SCF51.08c, sapA spore-associated protein precursor, FT len: 154 aa; N-terminal region identical to SW:SAPA_STRCO FT (EMBL:M20145) Streptomyces coelicolor spore-associated FT protein precursor (fragment) SapA, 120 aa" FT /db_xref="GOA:P12690" FT /db_xref="UniProtKB/Swiss-Prot:P12690" FT /protein_id="CAB59706.1" FT /translation="MQAVGATLTAVGAIGAGLLVTAPAAGAATAGATASYNGVCGSGYK FT VVNSMPIGSTGTVYLTYNSATGKNCTVTIRNTTGTPTYMVAYVRNIESGADQYDEGDYR FT SYAGPVYVSARGACVEWGGVIGNLQAWNYGSNCGALAAKAPQKDWFAGQR" FT RBS complement(130973..130976) FT CDS complement(131071..132321) FT /transl_table=11 FT /gene="SCO0410" FT /gene_synonym="SCF51.09c" FT /product="hypothetical protein" FT /note="SCF51.09c, hypothetical protein, len: 416 aa; FT similar to TR:Q49897 (EMBL:U00021) Mycobacterium leprae FT hypothetical protein MLC1351.13c, 311 aa; fasta scores: FT opt: 288 z-score: 317.7 E(): 2.5e-10; 34.4% identity in 326 FT aa overlap. Contains Pfam match to entry PF01513 DUF15, FT domain of unknown function and prosite PS00339 FT aminoacyl-transfer RNA synthetases class-II signature 2" FT /db_xref="GOA:Q9RJS6" FT /db_xref="InterPro:IPR002504" FT /db_xref="UniProtKB/Swiss-Prot:Q9RJS6" FT /protein_id="CAB59707.1" FT /translation="MMAYRHGTYSVPDARLAGRKREARHVAARPAAGVGEDSVDRGCGS FT TARRQEAVVTIERVGLVVHGGREGAAEAAREVREWCDENAVACTDIDVWSDTGRHSARE FT EVDAAGDPDLVVTLGGDGTFLRGARLAAENDALILGVDLGRVGFLTEVPAPAVRSALDA FT VRDGGLEPESRMLLTLRASRLLEIPAEMEALLRYGRGPLLPPPRVRTDCESGDEWGIAL FT NVTALNDVVLEKLSRDRQISVGVYIAGRLLASYSADALLVATPTGSTAYSFAAGGPVVS FT PRAEALVFTAVAPHMTFDRSVVTAPDEPVGLRILERSGRAAVSIDGQLRGVLDPGDWLG FT VYAAPRRLRAVRLGPMDFYGRLRERMRLTDAPAAVADGTPAPLWPVSTPPPGDLAHLAL FT PVPGAEGASGDLLREQS" FT misc_feature complement(131239..132159) FT /note="Pfam match to entry PF01513 DUF15, Domain of unknown FT function, score 150.90, E-value 2.2e-41" FT misc_feature complement(132136..132165) FT /note="PS00339 Aminoacyl-transfer RNA synthetases class-II FT signature 2" FT CDS 132327..132551 FT /transl_table=11 FT /gene="SCO0411" FT /gene_synonym="SCF51.10" FT /product="hypothetical protein SCF51.10" FT /note="SCF51.10, unknown, len: 74 aa. Contains a prosite FT match to entry PS00017 ATP/GTP-binding site motif A FT (P-loop)" FT /db_xref="UniProtKB/TrEMBL:Q9RJS5" FT /protein_id="CAB59708.1" FT /translation="MTFTEEEMEGVRAAAAAEGKSLKQYMHDLGVREMQRKRFVAGAVS FT WADRLRAEFDEAFPDEIPPSQRGEGVTAA" FT misc_feature 132366..132389 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 132551..132934 FT /transl_table=11 FT /gene="SCO0412" FT /gene_synonym="SCF51.11" FT /product="hypothetical protein SCF51.11" FT /note="SCF51.11, unknown, len: 127 aa" FT /db_xref="UniProtKB/TrEMBL:Q9RJS4" FT /protein_id="CAB59709.1" FT /translation="MSEPLYIDVPWLLDVQDAALDNEDVSVTDYSALVAAVARHKTRMP FT TLAASNPDSAWRAAALLHTVVRLEPLPHRNSLFAAFVTGQYMDQSGEGIDPPYGALSDL FT IRKVRETRLSIYDIADVLRSWRI" FT CDS complement(132962..133564) FT /transl_table=11 FT /gene="SCO0413" FT /gene_synonym="SCF51.12c" FT /product="hypothetical protein SCF51.12c" FT /note="SCF51.12c, unknown, len: 200 aa." FT /db_xref="UniProtKB/TrEMBL:Q9RJS3" FT /protein_id="CAB59710.1" FT /translation="MTTAHDLTIVSLEVPSDYPVERGDLSLALAGAELIDLMEAGTVEL FT DGDLLRPVSRAASGDRLLDEAASLLGGDPAESVTDWLWRRGDGLAARYLAAAGADEGGR FT RRPRRNARGGTGRPAPADPAAHRRATDRWSGADPVLAGFAAAVGVRHESADQVADPEDD FT GVATVLAAVNDVVVELAAIRQRRSIEEAAFDNIWRGM" FT RBS complement(133570..133574) FT CDS complement(133617..134513) FT /transl_table=11 FT /gene="SCO0414" FT /gene_synonym="SCF51.13c" FT /product="putative RNA polymerase sigma factor" FT /note="SCF51.13c, possible RNA polymerase sigma factor, FT len: 298 aa; similar to TR:CAB42013 (EMBL:AL049754) FT Streptomyces coelicolor putative RNA polymerase sigma FT factor SCH10.4c, 294aa; fasta scores: opt: 614 z-score: FT 721.0 E(): 8.7e-33; 41.4% identity in 285 aa overlap and to FT TR:O86856 (EMBL:AJ007313) Streptomyces coelicolor sigma FT factor, SigT, 236aa; fasta scores: opt: 160 z-score: 194.6 FT E(): 0.0018; 31.0% identity in 158 aa overlap" FT /db_xref="GOA:Q9RJS2" FT /db_xref="InterPro:IPR007627" FT /db_xref="UniProtKB/TrEMBL:Q9RJS2" FT /protein_id="CAB59711.1" FT /translation="MGTAGTSTDATVGERRQLINVAYRLLGSLAEAEDAVQEAYARWYA FT LPRSRQEEIVSPGAWLTTVTGRVCLDALGSARARRERYVGAWLPDPLPAHAERGPGHGA FT DPADQMVLDESVTMAFLVVLESMTPAERVAFVLHDVFRYPFADIAGILRRTPAACKQLA FT ASARRRVRGARAPQTPAAVRADVVRQVKEAWQTKDIAALVDLLDPAAVMTADGGGMVGT FT ALRPIEGGARIAQYMAAVADKAPGLELLERSVNGVPGLVARRDGAVMTVAAFDVADGRV FT TRIWVVRNPEKLGPWVG" FT RBS complement(134526..134529) FT CDS 134615..134977 FT /transl_table=11 FT /gene="SCO0415" FT /gene_synonym="SCF51.14" FT /product="putative membrane protei" FT /note="SCF51.14, possible integral membrane protein, len: FT 120 aa. Contains possible hydrophobic membrane spanning FT regions" FT /db_xref="UniProtKB/TrEMBL:Q9RJS1" FT /protein_id="CAB59712.1" FT /translation="MATQATAQHRLSFLRIAIALQTLTIFLQAVSAGLLLTASYGETLH FT SVGARVMYGASMLYVLAAVLAWKPGGGPLRPVRHACGFLVLASVQVVLGIAHVPSVHLP FT LGVLMFGLSVLALARR" FT CDS complement(134984..135589) FT /transl_table=11 FT /gene="SCO0416" FT /gene_synonym="SCF51.15c" FT /product="probable integral membrane protein" FT /note="SCF51.15c, probable integral membrane protein, len: FT 201 aa; similarity to SW:CMLR_STRLI (EMBL:X59968) FT Streptomyces lividans chloramphenicol resistance protein, FT 392aa; fasta scores: opt: 123 z-score: 149.4 E(): 0.6; FT 30.5% identity in 177 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9RJS0" FT /protein_id="CAB59713.1" FT /translation="MRFVPRWVLLSSGCAPVLLIAGWTGAAYAEGASYDPVSQTISVLG FT AYGAAGFWVMTAAFLALGVCHLLTAWGLRPAATAGRVALGGGGLAALVLVALPAPSSGG FT SLRHGAVVVVGFTLLAVWPVLAVNGGPAGPWALRLAPSIAVTTLMAAGGVWFLIEMRQH FT GDAGVAERVVTSLQSLWPFVVAASCLRHARRPGTAPEG" FT CDS complement(135651..136397) FT /transl_table=11 FT /gene="SCO0417" FT /gene_synonym="SCF51.16c" FT /product="conserved hypothetical protein SCF51.16c" FT /note="SCF51.16c, hypothetical protein, len: 248 aa; FT similar to TR:P74164 (EMBL:D90912) Synechocystis sp. FT (strain PCC 6803) hypothetical 33.9 KD protein, 300 aa; FT fasta scores: opt: 361 z-score: 423.5 E(): 3.2e-16; 35.9% FT identity in 259 aa overlap" FT /db_xref="InterPro:IPR014990" FT /db_xref="UniProtKB/TrEMBL:Q9RJR9" FT /protein_id="CAB59714.1" FT /translation="MTTPAQSLRSLARTRASLDGEEVTYWWSGSVFAWAPDEPYERLFG FT FEGVNVARLVHDAEDGPDSYRLLTREAAFYLDPVTGDILETWRDQPVVHVWNDPANQKW FT RPFPVPTTDLGDQVCFSLEIPLAYPSPLPTAQYPRHSAGDMYRALELFQFFARREDLAG FT PDPSVPATMSWTRMSPWVPWMARGGRPGGLTYHCRGRKLGSYTEVPERTRAHIAGHHPR FT FARAPERWSEPNETSWTYFRALNPPV" FT CDS 136456..137103 FT /transl_table=11 FT /gene="SCO0418" FT /gene_synonym="SCF51.17" FT /product="DNA-binding protein" FT /note="SCF51.17, DNA-binding protein, len: 215 aa; similar FT to TR:CAB44405 (EMBL:AL078610) Streptomyces coelicolor FT putative DNA-binding protein, SCH35.22c 215 aa; fasta FT scores: opt: 206 z-score: 233.8 E(): 1.2e-05; 30.9% FT identity in 220 aa overlap and to TR:CAB45035 FT (EMBL:AL078635) Amycolatopsis orientalis hypothetical FT protein CZA382.14c, 202 aa; fasta scores: opt: 305 z-score: FT 340.6 E(): 1.3e-11; 34.0% identity in 212 aa overlap" FT /db_xref="GOA:Q9RJR8" FT /db_xref="InterPro:IPR002734" FT /db_xref="UniProtKB/TrEMBL:Q9RJR8" FT /protein_id="CAB59715.1" FT /translation="MNPGGGPGLPCMTRIIADISISLDGCVTGPDPGPGNGLGTGGEAL FT HTWAFSDDPEERRIVRETTARSGAVVLGRRLFDLVDGPGGWDDTVGYGAAEVGRPPFVV FT VTASPPESVRLTGLDWTFVTTGLPDAVAAARERAEAASADLGRDLDVVLMGGGALIGSA FT LDAGLVEVLSLHLAPVVLGSGTPLFTGGTPHTLVRRSANATPNATHLLYEVL" FT RBS 137215..137218 FT CDS 137235..138224 FT /transl_table=11 FT /gene="SCO0419" FT /gene_synonym="SCF51.18" FT /product="putative zinc-binding oxidoreductase" FT /note="SCF51.18, possible zinc-binding oxidoreductase, len: FT 329 aa; similar to SW:QOR_PSEAE (EMBL:X85015) Pseudomonas FT aeruginosa quinone oxidoreductase (EC 1.6.5.5) FT (NADPH:quinone reductase) qor, 325 aa; fasta scores: opt: FT 420 z-score: 452.5 E(): 7.8e-18; 32.8% identity in 332 aa FT overlap and to TR:CAB45348 (EMBL:AL079345) Streptomyces FT coelicolor putative dehydrogenase SCE68.12c, 318 aa; fasta FT scores: opt: 535 z-score: 574.1 E(): 1.3e-24; 38.6% FT identity in 332 aa overlap. Contains Pfam match to entry FT PF00107 adh_zinc, Zinc-binding dehydrogenases" FT /db_xref="GOA:Q9RJR7" FT /db_xref="HSSP:1IYZ" FT /db_xref="InterPro:IPR013154" FT /db_xref="UniProtKB/TrEMBL:Q9RJR7" FT /protein_id="CAB59716.1" FT /translation="MKAVVQERFGPPDSLRLRDVDRPHAGAGQVLVRVHAAAVNPYDWH FT MLRGDPYVARMLGGMGLTRPKCPVAGLDAAGVVERVGADVRGFGPGDRVLGFCPGAFAE FT YACTTAPMLVPVPEGLTFEQAAALPMAAVTALRGIRTVGRVRSGQRVLVNGAGGGVGTF FT AVQIAAVLDAEVTGVCSAANTDLVRSLGAAHVLDYAREDFTDGRGRYDVVLDNVGNHPL FT RRLRRALTPAGVLVANGGGSPGRVFGAVGAMLRLAAANAVTRQRLRPILPATPDGPVHE FT DLSAVTALVDAGQVTPVVGRTFALADTARALRHVEEGHARGKTVVTVA" FT misc_feature 137253..138215 FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score -9.20, E-value 2.9e-09" FT CDS complement(138253..139287) FT /transl_table=11 FT /gene="SCO0420" FT /gene_synonym="SCF51.19c" FT /product="putative homoserine dehydrogenase" FT /note="SCF51.19c, possible homoserine dehydrogenase, len: FT 344 aa; similar to SW:DHOM_SYNY3 (EMBL:D64001) FT Synechocystis sp. (strain PCC 6803) homoserine FT dehydrogenase (EC 1.1.1.3) (HDH), 433 aa; fasta scores: FT opt: 284 z-score: 307.6 E(): 9.2e-10; 29.0% identity in 335 FT aa overlap and to TR:O26517 (EMBL:AE000826) FT Methanobacterium thermoautotrophicum homoserine FT dehydrogenase homologue MTH417, 340 aa; fasta scores: opt: FT 332 z-score: 359.9 E(): 1.1e-12; 30.1% identity in 335 aa FT overlap. Contains Prosite match to entry PS01042 Homoserine FT dehydrogenase signature" FT /db_xref="GOA:Q9RJR6" FT /db_xref="InterPro:IPR019811" FT /db_xref="UniProtKB/TrEMBL:Q9RJR6" FT /protein_id="CAB59717.1" FT /translation="MNELTGATETTGATTTAVVLAGYGPVGQAFVDRLARDGEALARRH FT GVRPRVAAVRASAAQCRPDAGGSVPPRSRWDPARPLDETFDRTGARVFVQAVPSSPGLR FT ERAAEEALAALRRGIHVVTATKSHLLTHWRDLDAAARAGGSMIRISGATGAALPAGDLS FT RTSLRGLDCRTIRACPNGTATFVLDRLAEGDTLGDAIRAAQLRGIAEADPSADLSGDDA FT ATKVRLLAALAWGWDPAEVRVRAEPVDGTTARRALAAAARSRRLRAVAGAAVAEPGVVR FT VRLEETEAGDPLHALTGPEKAAVFGCPDAGDVTVSGGRSSPVGAALALVKDTVEVTAAR FT TGFH" FT misc_feature complement(138613..138681) FT /note="PS01042 Homoserine dehydrogenase signature" FT RBS complement(139299..139303) FT CDS complement(139329..139988) FT /transl_table=11 FT /gene="SCO0421" FT /gene_synonym="SCF51.20c" FT /product="putative two-component response regulator" FT /note="SCF51.20c, possible two-component response FT regulator, len: 219 aa; similar to TR:CAB51249 FT (EMBL:AL096872) Streptomyces coelicolor putative FT two-component response regulator, SC5F7.36c, 227 aa; fasta FT scores: opt: 815 z-score: 952.9 E(): 0; 61.8% identity in FT 220 aa overlap and to TR:Q53894 (EMBL:U51332) Streptomyces FT coelicolor absA2, 222 aa; fasta scores: opt: 543 z-score: FT 638.7 E(): 3.3e-28; 43.8% identity in 217 aa overlap. FT Contains two Pfam matches to entries PF00196 GerE, FT Bacterial regulatory proteins, luxR family and PF00072 FT response_reg, Response regulator receiver domain and FT Prosite match to entry PS00017 ATP/GTP-binding site motif A FT (P-loop). Contains possible helix-turn-helix motif between FT residues 14157..14222, score 1198 (+3.27 SD)" FT /db_xref="GOA:Q9RJR5" FT /db_xref="HSSP:1FSE" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9RJR5" FT /protein_id="CAB59718.1" FT /translation="MLLADDQALLRATFRILIDSSEDMDVVAEAADGRDAVELTRTHRP FT DIVLMDIRMPGTDGLAATAEICADPALRGTRVLILTTFETDEHVARALRIGASGFLGKD FT VTAEELLDGIRTVAAGDALLSAAATRSLITRFLDSPDPRASPVPPEDLAALTAREREVT FT ALVADGKSDKEIAAELFLSPLTVRTHVQRAKTKLGARDRAQLVAHAYRSGLARPPR" FT misc_feature complement(139338..139535) FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 82.90, E-value FT 6.4e-21" FT misc_feature complement(139416..139481) FT /note="Helix-turn-helix from SCF51.20c score 1198" FT misc_feature complement(139476..139499) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(139647..139988) FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 107.80, E-value 2.1e-28" FT CDS complement(139997..141190) FT /transl_table=11 FT /gene="SCO0422" FT /gene_synonym="SCF51.21c" FT /product="putative two-component sensor kinase" FT /note="SCF51.21c, possible two-component sensor kinase, FT len: 397 aa; similar to TR:CAB51250 (EMBL:AL096872) FT Streptomyces coelicolor putative two-component sensor FT kinase, SC5F7.35c, 416 aa; fasta scores: opt: 841 z-score: FT 875.2 E(): 0; 43.5% identity in 393 aa overlap and to FT TR:Q53893 (EMBL:U51332) Streptomyces coelicolor AbsA1,571 FT aa; fasta scores: opt: 369 z-score: 385.9 E(): 4e-14; 30.5% FT identity in 394 aa overlap. Contains possible hydrophobic FT membrane spanning regions" FT /db_xref="GOA:Q9RJR4" FT /db_xref="InterPro:IPR003594" FT /db_xref="UniProtKB/TrEMBL:Q9RJR4" FT /protein_id="CAB59719.1" FT /translation="MLSSWRRYADSHPHLVETAFLLLVLAVTSRQYVHQGPGWWQGQPL FT ALVATAGLLPRRGHPRAAVLVTAACAAASVALGYLISPLLLLPVLIALYELAVRTPQRT FT AYACYGATVALVVPAALLSARDGRPWMDESVGPVFWILLPVLAGTAVRNRRAHLDAVHT FT RAEHAERTREEEARHRVAEERIRIARELHDVVAHHMALANAQASTAAHLARTHPEQAHE FT ILTHLTGTTASALRELKATVGLLRSPDDTGDTGGPDDLRPPPGLGRLPELVSAFGSAGL FT HVTVTVRGTRRPLPPGVDLTAFRIVQEALTNVTKHTDAGTADVHLAYAHDRLTLTVTDD FT GGASPRPPGPGGGFGLVGMRERAETSGGRLSAGTLADGGFAVTAELPAPPPAREQPS" FT RBS complement(141197..141201) FT stem_loop 141227..141280 FT CDS complement(141282..143579) FT /transl_table=11 FT /gene="SCO0423" FT /gene_synonym="SCF51A.01c" FT /product="putative membrane transport protein" FT /note="SCF51A.01c, putative membrane transport protein, FT len: 765 aa. Similar to many Streptomyces coelicolor FT integral membrane proteins including:TR:Q53902 (EMBL; FT M64683) ORF1-4 (ACTII) (711 aa),fasta scores opt: 291 FT z-score: 295.3 E(): 4.3e-09 27.7% identity in 779 aa FT overlap, TR:Q9Z577 (EMBL; AL035569) SC8D9.14 (748 aa), FT fasta scores opt: 1021 z-score: 1028.4 E(): 0 40.6% FT identity in 773 aa overlap and TR:O88022 (EMBL; AL031107) FT SC5A7.16C (705 aa), fasta scores opt: 639 z-score: 645.0 FT E(): 1.4e-28 37.2% identity in 764 aa overlap. Contains FT multiple possible transmembrane hydrophobic domains." FT /db_xref="GOA:Q9RL63" FT /db_xref="InterPro:IPR000731" FT /db_xref="UniProtKB/TrEMBL:Q9RL63" FT /protein_id="CAB56653.1" FT /translation="MATLLYRLGRGAFRRRRWVTLAWAAVVLGVVLGAMSAGEAGDDSD FT SMPGIESQHAFDLINERFPGAEAEGADARIVLVAPDGRQVTASEYRAAIDTLVAEVADG FT PQVAAVSDPLDAATVSQDGSTAYATVTYEVTEDNVTDAGRADLTAAVERARTSGLTVEA FT GGGAVAGEPPAGIGEFLGIGVAAVVLLITFGSLAAAGLPLITAVVGVALTLASIVALGS FT ALGMSTASGDLAMMIGIAVGVDYALLVVSRYREERAEGHDAREAAGLAVGTAGSAVVFA FT GLTVVIALAGLSVIGVPSLTKMGLAAAGAVVIAVLITLTLVPALCGFWPDALLARRVRK FT GRSAPPARRFRKGRSTPPARRLRGGPGRGAARRTREAGAWSVRWARFVQRRPVPVLLGS FT AVLLGALAVPALDLRLGMPGDEAKPTSTTERRAYDALADGFGPGFNGPLTVVVDARQAD FT DPRSAVAAVSDRLAATAGVVSVAPPRFNAAKDTAVIQAVPATAPTSERTEELVHTIRDE FT RHATESATGATFEVTGTTALNIDVARKMTDALIPYLLVVVGLAFLLLLVVFRSVLVPLK FT AALGFLLSVGASFGALVTIFQNGHGAGLLGVEETGPVMSTMPLMLVGIVFGLAMDYQVF FT LVSRMREAVVHGERPAEAVVTGFRHSGRVVTAAAVIMTSVFAGFMTGGETLLKMVGFGL FT AVAVLFDAFVVRMAFVPAVLVLLGERAWWLPRRLDRLLPRVDVEGEALGRRTPAPALAA FT VPDTDRQDTVRA" FT RBS 143692..143697 FT CDS 143700..144191 FT /transl_table=11 FT /gene="SCO0424" FT /gene_synonym="SCF51A.02" FT /product="hypothetical protein SCF51A.02." FT /note="SCF51A.02, unknown, len: 168 aa." FT /db_xref="UniProtKB/TrEMBL:Q9RL62" FT /protein_id="CAB56654.1" FT /translation="MPGWTAGLPHLPKRPRGHGAGRGDPDGPRVSAVPAAQCVEWGPGR FT RRGGPRTAVATARGPTVRPGPHQFGGGPLEHRQRLGIAVLGGRAEFEEAPGRQVAAARA FT TRACPASGRSAGTRIASVQVPGPARRSRRPGAVVGAAVPGRPHRAAAGRDDVALAARQA FT " FT CDS complement(144293..145243) FT /transl_table=11 FT /gene="SCO0425" FT /gene_synonym="SCF51A.03c" FT /product="hypothetical protein SCF51A.03c" FT /note="SCF51A.03c, unknown, len: 316 aa. Similar to FT Streptomyces coelicolor TR:CAB46385 (EMBL; AL096743) FT hypothetical 30.5 KD protein SCI7.02C (281 aa), fasta FT scores opt: 424 z-score: 490.6 E(): 5.7e-20 36.6% identity FT in 292 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9RL61" FT /protein_id="CAB56655.1" FT /translation="MTLSLTHVHGDRVTVAHGAAGTELFSYVYRPEAAWEAPKPYLHPV FT RTLSGAVVTDYRPNDHRWHKGLQLTASHLSGQNLWGGNTYVHGEGYRALPERVGSMAHV FT SFEEIGAEADHAVIAERLTWHPHGGELWAEEERRIEVRDVDPDTGSWTLTWTSAVTNRR FT AEPLRFGSPTTHGRPAAGYTGLFWRGPRAFRGGRVFTAQSAASAESGEPADAGPMGSSA FT RWLAYVGEHDGRDGHATLVFEHAPSNDHSGEKGTHPAHWFVRSDPFAAVAPSWAFHEEL FT VLPPGETLARAYRVVVADGAWDRARVAAHLAGLAW" FT RBS complement(145248..145253) FT RBS 145428..145430 FT CDS 145441..145671 FT /transl_table=11 FT /gene="SCO0426" FT /gene_synonym="SCF51A.04" FT /product="hypothetical protein SCF51A.04." FT /note="SCF51A.04, unknown, len: 76 aa." FT /db_xref="UniProtKB/TrEMBL:Q9RL60" FT /protein_id="CAB56656.1" FT /translation="MEIPRHLIELRRAVEAADNRYRSNRGENATVALAVWSDATAALAR FT GIAAYADETGVPHREVELAVQRATGRHTPAR" FT RBS 145744..145747 FT CDS 145752..146588 FT /transl_table=11 FT /gene="SCO0427" FT /gene_synonym="SCF51A.05" FT /product="putative hydrolase" FT /note="SCF51A.05, possible hydrolase, len: 278 aa. Similar FT to many e.g. Pseudomonas fluorescens SW:PRXC_PSEFL FT (EMBL:AF031153) non-heme chloroperoxidase (EC 1.11.1.10) FT (chloride peroxidase), fasta scores opt: 243 z-score: 282.1 FT E(): 2.4e-08 28.4% identity in 275 aa overlap and many FT putative hydrolases: Streptomyces coelicolor TR:CAB44393 FT (EMBL; AL078610) putative hydrolase SCH35.34C (269 aa), FT fasta scores opt: 259 z-score: 300.1 E(): 2.3e-09 29.7% FT identity in 269 aa overlap. Contains a Pfam match to entry FT PF00561 abhydrolase, alpha/beta hydrolase fold" FT /db_xref="GOA:Q9RL59" FT /db_xref="InterPro:IPR000073" FT /db_xref="UniProtKB/TrEMBL:Q9RL59" FT /protein_id="CAB56657.1" FT /translation="MTERLAVDGGTIAYEVTGSGPLIVLAHGMGDSRAAYRTVVPQLVA FT AGHRVAAVDLRGCGESSVDWPQWSRTAIAGDLIALIRHLGGPAVVVGHSVSGGAATIAA FT AREPSLVTAVVELAPFTRKQSVRLGDLRVKRFRRGMLRLLGAGAFGSLPLWRSYLDVAY FT PGVKPAHWSERLGRIESLLREPGRMKAMQAMGRSAPTDAGAQLGNVRCPVLVVMGTLDP FT DWADPHAEGSAVVADLPSGLGRLEMIEGAGHYPHDQFPDEVAALVLAFLRSDAARA" FT misc_feature 145893..146564 FT /note="Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold, score 74.40, E-value 2.4e-18" FT RBS 146604..146608 FT misc_feature 146611..146721 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 17.50, E-value FT 0.0041" FT CDS 146611..147144 FT /transl_table=11 FT /gene="SCO0428" FT /gene_synonym="SCF51A.06" FT /product="putative tetR family transcriptional regulator" FT /note="SCF51A.06, possible tetR family transcriptional FT regulator, len: 177 aa. Similar to many putative regulators FT e.g. Streptomyces coelicolor TR:Q9ZBU4 (EMBL; AL034446) FT putative transcriptional regulator SC1A9.08C (189 aa), FT fasta scores opt: 402 z-score: 476.9 E(): 3.3e-19 45.5% FT identity in 165 aa overlap. Contains a Pfam match to entry FT PF00440 tetR, Bacterial regulatory proteins, tetR family FT and a possible helix-turn-helix motif between residues FT 18..39 (+2.91 SD)." FT /db_xref="GOA:Q9RL58" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9RL58" FT /protein_id="CAB56658.1" FT /translation="MVAAGAALADEVGFANLTMGLLAERVGVRTPSLYKHVGGQDDLTR FT RIAVRALNEAADAVGGAVQGYAGRDALAAAARAFRAFVLEHPGRYAATIGQEPSGPDDP FT LAAAGQRLLGAFTAVLRGYDIEDRDVNHALRLLRSLFHGFATLQASDGFQWSTDVDDSF FT EWLIAFTDRGLRTL" FT CDS complement(147214..148161) FT /transl_table=11 FT /gene="SCO0429" FT /gene_synonym="SCF51A.07c" FT /product="putative oxidoreductase" FT /note="SCF51A.07c, possible oxidoreductase, len: 315 aa. FT Weakly similar to many eukaryotic oxidoreductases e.g. FT Hordeum vulgare (Barley) TR:Q42837 (EMBL; Z48360) aldose FT reductase (EC 1.1.1.21) (aldehyde reductase) (320 aa), FT fasta scores opt: 236 z-score: 263.3 E(): 2.6e-07 27.0% FT identity in 296 aa overlap and many other putative FT oxidoreductases e.g. Streptomyces coelicolor TR:CAB42953 FT (EMBL:AL049863) putative oxidoreductase SC5H1.28C (305 aa), FT fasta scores opt: 563 z-score: 617.0 E(): 5.2e-27 39.7% FT identity in 305 aa overlap" FT /db_xref="GOA:Q9RL57" FT /db_xref="InterPro:IPR020471" FT /db_xref="UniProtKB/TrEMBL:Q9RL57" FT /protein_id="CAB56659.1" FT /translation="MTSTGTPSSSRATHGGTPRPGGAGVLAGRTVSRIGYGAMQLERLH FT ADRAAAVALVRRAVERGVDHLDTAQFYGDGFVNEVIRAALRPADDVVVVSKVGAAPDPG FT GPLPLRPAQRPEELRASVEDNLRSLGTDRIPVVNLRRLDTGPGLRAEGDQRVDLDDQLA FT VMTALRDEGKIGAIGLSSVTPDGLRRALPAGIVCVQNAYSVVSRDDEDMLALCSAEGVA FT WVPYFPLGGAFPAMPKVADEPAVHTVANRLGVTPAQVGLAWLLHHAPNVLLIPGTADAG FT HLDANLAVGEIALDASSLAALDAVRSRSADVPLG" FT RBS complement(148172..148176) FT CDS 148185..148868 FT /transl_table=11 FT /gene="SCO0430" FT /gene_synonym="SCF51A.08" FT /product="putative tetR family transcriptional regulator" FT /note="SCF51A.08, possible tetR family transcriptional FT regulator, len: 227 aa. Similar to several putative FT regulators e.g. Streptomyces coelicolor TR:CAB46405 (EMBL; FT AL096743) putative transcriptional regulator SCI7.22c (202 FT aa), fasta scores opt: 428 z-score: 495.6 E(): 3e-20 41.1% FT identity in 202 aa overlap. Contains a Pfam match to entry FT PF00440 tetR, Bacterial regulatory proteins, tetR family FT and a possible helix-turn-helix motif between residues FT 71..92 (+3.86 SD)." FT /db_xref="GOA:Q9RL56" FT /db_xref="InterPro:IPR001647" FT /db_xref="UniProtKB/TrEMBL:Q9RL56" FT /protein_id="CAB56660.1" FT /translation="MTVAEDPPLYDCNTTGGSSALSPDQETSADPGRPDRPAGAERPLR FT AHARRNREKLVAAARAAFTAADDTVPLDGIARAAGVGIGTLYRHFPTREALVEAVYAAE FT LDDVTASASALLDTLPPERALRAWLERYAAFVATKRSILNTLHSGWASGRLVMPATRER FT ITAAIGTMLAQGARAGSLRGDVAPDDVTAMLLGVFLSTAADDEPERTERLLDLVVDALR FT PPGSS" FT misc_feature 148347..148484 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 29.80, E-value FT 1.5e-06" FT CDS complement(148890..150218) FT /transl_table=11 FT /gene="SCO0431" FT /gene_synonym="SCF51A.09c" FT /product="putative secreted protein" FT /note="SCF51A.09c, possible secreted protein, len: 442 aa; FT similar to TR:Q9KZR1 (EMBL:AL353832) Streptomyces FT coelicolor putative secreted protein SCE6.29, 454 aa; fasta FT scores: opt: 614 Z-score: 655.9 E(): 6.7e-29; 31.278% FT identity in 454 aa overlap. Contains a possible N-terminal FT signal sequence" FT /db_xref="GOA:Q9RL55" FT /db_xref="InterPro:IPR001087" FT /db_xref="UniProtKB/TrEMBL:Q9RL55" FT /protein_id="CAB56661.1" FT /translation="MRRLLARVPDPARAPLARGVATALALTLASSVLAASTSTAAAPAG FT TERDGRPGGNAWFTSWAASQQNVAPTPLRDQSMRMITHLSQGGDAVRIRVQNTFGDSPL FT TVDAATVAHSDGKDAATEGRPRPVTFDGRPRVVVPPGGEVWSDSTGLRTAAQDDIAVSL FT SVSGTVAPGRHDSAFRTNYLTPPGSGDHTADPDGTAFTGTTGSTLLVSAVDVRNPRLRG FT SLVAYGSSVVDGTGSTNCGPDCSRPGADLRWTDDLARRITSELPPNRQFAVANAGIGGT FT TSAATCPGTGDSVRGLDAAARLERDVLSLHGVTGVLYYYGTNDLPAGCDAARIEASYRE FT VFQRLRAAGIKVYVTPITPRPGYTDQHNRDRHAVGTFVSKWNSCGGTCDGILPFDQVLE FT DPVRPNSINPPYDTGDGVHANIAGQQALADIVSLPMLAASARR" FT RBS 150501..150504 FT CDS 150515..154252 FT /transl_table=11 FT /gene="SCO0432" FT /gene_synonym="SCF51A.10" FT /product="probable secreted peptidase" FT /note="SCF51A.10, probable secreted peptidase, len: 1245 FT aa. Highly similar to Streptomyces albogriseolus TR:P95684 FT (EMBL; D83672) subtilisin-like protease (1102 aa), fasta FT scores opt: 1572 z-score: 1550.1 E(): 0 34.4% identity in FT 1259 aa overlap. Also similar to the much smaller FT subtilisins e.g. Bacillus sp. (strain TA39) SW:SUBT_BACS9 FT (EMBL; X62369) subtilisin precursor (EC 3.4.21.62) (420 FT aa), fasta scores opt: 485 z-score: 483.5 E(): 1.4e-19 FT 38.2% identity in 304 aa overlap. Contains a Pfam match to FT entry PF00082 Peptidase_S8, Subtilase family and a possible FT N-terminal signal sequence." FT /db_xref="GOA:Q9RL54" FT /db_xref="HSSP:1SUE" FT /db_xref="InterPro:IPR000209" FT /db_xref="UniProtKB/TrEMBL:Q9RL54" FT /protein_id="CAB56662.1" FT /translation="MRRIRLLAAISAGLALAAGAVAPVPALASTPRPDAAAPSADHGTA FT TDHGTATVKLITGDSVTVTRAGDGRQAASVTPGPGRRGVLFRTLEQDGHVTVLPSDADA FT LVAAGRLDRDLFDVTALLAQRYDTAHTDALPLIVERAEGVAASSVNALTDLARDASVRE FT LDSIDARAVRVDEAELGRFWKRLVPAGGQRAKAAAATPRVWLDGRVGASLDRSTAQIGA FT PDVWSAGYRGDGVKVAVLDTGADQSHPDLAGRVAAAKDFSGSSGTNDVFGHGTHVASIV FT GGSGAASGGSRQGVAPAARLLVGKVLGDDGFGSESQVIAGMEWAADQGADVVNMSLGSS FT GATDGTDPMSQALNDLSRRTGTLFVVAAGNEGEQGPRTVGSPGAADAALTVGAVDRDDS FT LAPFSSRGPRLGDDAVKPDVTAPGVGIVAARAAGSAMGDPVDEHYTAASGTSMATPHVA FT GAAALLAQRHPDWTGAQLKDALISTAVTVDGQKVTEQGGGRIDVRAAGLGAVTATGTLV FT MGPFTSRDTEPVTSRVRYTNSSDEDVTLSLAVELATEGGKAPAEGSARLGSDSVRVPAG FT SSAEVPLTVDPARAGQGKFYGYVTATTADGSVAAHTTLSLVVHGPTHRITVRTIDKDGE FT QVADLPTIWGAEGFVGYSDPAAAVAEVEEGVYQLNTSWTTSAEDGEELRHVVLPEVKVT FT KDMTVTLDARKTVPVEIRTPRPAEQRGILSYQTYREIGGRSLTQGTMYFDIAKRLYISP FT TAKVTEGTFEFASRWQLVAPLVEAKVSRTGFDLGAYYMPASPLLPERGATLTAVDAGVA FT ADADFSRARGRVAVVDNPTGAGERALVERAAAAGVSAVILVHFNDTGWTRWRPTGDRNA FT LPTLRIGKGTGAELLARIARGSTSVRFSGTARSPYLYDVMQVSEQQVPRKVVHSVSARN FT SAVVRTTYADNGVTGWASEQRFGWRPYQNTAWLQYTRFVPLGFERTEYVSAGDTAWQHR FT VHHTTTFDVDQPLIAGMRDDPRTYRAGVRPRETWQGAVVRPSIPAGTTTPTVRDGNVLR FT LRVAEFTDSQAGHWSPPSGGDTASAVLYRDGERVDGVGSAWQNVTVPAERARYRLDMET FT SRDSEAWTRGVATSTSWSFESGRTDAAAPLSLLQLDYDVPVDVRNSVRGTRSHHVEVRV FT RTQEGLPVPRGVSVRVEASYDDGRTWSSARTHAHGRNAFRASLTPPARGESWVTLRVTA FT RDAAGDSVRQTVQRAYAVRR" FT misc_feature 151166..152035 FT /note="Pfam match to entry PF00082 Peptidase_S8, Subtilase FT family, score 187.70, E-value 1.8e-52" FT RBS 154359..154363 FT CDS 154370..155374 FT /transl_table=11 FT /gene="SCO0433" FT /gene_synonym="SCF51A.11" FT /product="putative transcriptional regulator" FT /note="SCF51A.11, possible transcriptional regulator, len: FT 334 aa. Similar to Streptomyces coelicolor TR:Q9ZBT5 (EMBL; FT AL034446) putative regulatory protein SC1A9.17C (327 aa), FT fasta scores opt: 494 z-score: 573.8 E(): 1.3e-24 36.9% FT identity in 333 aa overlap. Contains a possible FT helix-turn-helix motif between residues 290..311 (+2.71 FT SD)." FT /db_xref="GOA:Q9RL53" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9RL53" FT /protein_id="CAB56663.1" FT /translation="MVLEIAGLSPDEESVYALLVTFGRAGAADLAERDGMPVERMDRVL FT ESLTAKGLASPTDGVPRLYQAAPPDVALLPRLKRSAEALDLAQHEAARLIESYRDTMRR FT RDAGQLLEVITGAEALRQHLRQIQTSVREEMLWFCKAQYVAMPSGSNTEEFEALARGVR FT YRVLYEKAFFDDEGAVDNVVAGVRAGEVARAVPQLPLRLAIADRAVAVFPLVAGGPHGS FT PEEPTTALVRDSNLLAALIALFERYWEDAVPLDVDDSGELSGTDGPAAPDALAPTDRRL FT LSLLVAGVADKAIASQMQLSRRTVQRRIQGMMERANAATRMQLAWQAARRGWL" FT CDS 155546..157195 FT /transl_table=11 FT /gene="SCO0434" FT /gene_synonym="malX" FT /product="sugar phosphotransferase" FT /note="SCF51A.12, malX, sugar phosphotransferase, len: 549 FT aa. Highly similar to Escherichia coli SW:PTOA_ECOLI (EMBL; FT M60722) PTS system, maltose and glucose-specific II ABC FT component (maltose and glucose-permease II ABC component) FT (phosphotransferase enzyme II, ABC component) (EC 2.7.1.69) FT (523 aa), fasta scores opt: 1852 z-score: 2064.1 E():0 FT 59.5% identity in 543 aa overlap. Contains a Pfam match to FT entry PF00367 PTS_EIIB, phosphotransferase system, EIIB and FT a Prosite hit to PS01035 PTS EIIB domains cysteine FT phosphorylation site signature. Contains multiple possible FT membrane spanning hydrophobic domains" FT /db_xref="GOA:Q9RL52" FT /db_xref="HSSP:1O2F" FT /db_xref="InterPro:IPR018113" FT /db_xref="UniProtKB/TrEMBL:Q9RL52" FT /protein_id="CAB56664.1" FT /translation="MQKTKAALWEFLQGLGKTFMLPVALLAFCGIMLGIGSSLSSDAVT FT DNVAFLKGEGFHLVFTWMANTGLVAFTFLPVLFAMAIPLGLAREDKGVAAFSGFVGFVA FT MNLAVNFYLTAKGVDFEDEKAIEHYGIADVLGVQSIDTGLLGAVAVGIVVSLLHRRFRT FT QRMPDALAFFGGLRFVPIVSALVLSVLGLLIPLVWPTFNGWISAVGRGIGHTGVFGPFF FT FGMGEVLLRPIGLHHILVAMFRFTDVGGSGTVCGDHVSGALNLFYAQLDCSAAPGSAVT FT DATHFLSQGKMAAYLGGLPGAALAMYHCARRRMRPEIKALLVSGVVACVVGGITEPLEF FT LFLFVAPWLYLVHAVLVGLGFLTAAVLGVFIGNTDGNVIDWLVFGVLQGSTTKWYLVPV FT IAAVWFAAYYFLFRWAITRFDLKTPGREDPPADDDHDEHDEHDGAHDAEHAEEQVRAAP FT EPARELVAGKYDAAAMLDAIGGAGNIRSLDNCITRLRMTVADAEAVDEARLKKLGAVGV FT VKLDGHNVQVVIGPQVQSVKDAIATMVPAGRP" FT misc_feature 156956..157060 FT /note="Pfam match to entry PF00367 PTS_EIIB, FT phosphotransferase system, EIIB, score 51.00, E-value FT 3.7e-13" FT misc_feature 156992..157045 FT /note="PS01035 PTS EIIB domains cysteine phosphorylation FT site signature." FT CDS 157192..158397 FT /transl_table=11 FT /gene="SCO0435" FT /gene_synonym="malY" FT /product="aminotransferase" FT /note="SCF51A.13, malY, aminotransferase, len: 401 aa. FT Highly similar to Escherichia coli SW:MALY_ECOLI (EMBL; FT M60722) MalY protein (EC 2.6.1.-) (390 aa), fasta scores FT opt: 1577 z-score: 1814.7 E():0 58.5% identity in 386 aa FT overlap" FT /db_xref="GOA:Q9RL51" FT /db_xref="HSSP:1D2F" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:Q9RL51" FT /protein_id="CAB56665.1" FT /translation="MTAHSAPAAPGPASAPYDFDTPVDRRGTWCTQWDYVQDRFGVPDL FT LPFTISDMDFETAPEVLAALRGRLEHGVLGYSRWRQDDFLSAIVHWYAARHGTAVDPGS FT VVYAPSVVYQVSRLLHLWSRPGDGVVAHTPMYDAFPRTVAASGRRLLECPLDDWPELER FT LLALPDTAVLLLCSPHNPTGRVWSAAELDRMARLCARHGVAVVSDEIHSDLAHAPHLHR FT PWVRHAGDGRWAVVTSASKSFNIPALTGSYGIIGDPASRDAYLRQLKDADGLSSPAVLS FT LVGHIAAYREGAPWLDALRTYLAGNLAMVADRLRAAFPGLDWRPPQAGYLAWIDLRPLG FT VDDEELQRELVEVEKVAVMPGAAYGSPGRVRLNVGCPRSKAEAGVEALVRALGRLTGTQ FT RR" FT RBS 158469..158476 FT CDS 158484..158654 FT /transl_table=11 FT /gene="SCO0436" FT /gene_synonym="SCF51A.14" FT /product="probable 50S ribosomal protein" FT /note="SCF51A.14, possible 50S ribosomal protein L32, len: FT 56 aa. Similar to many including: Helicobacter pylori J99 FT SW:RL32_HELPY (EMBL; AE000540) 50S ribosomal protein L32 FT (48 aa), fasta scores opt: 85 z-score: 146.1 E(): 0.89 FT 30.2% identity in 43 aa overlap and highly similar to the FT N-terminus of Streptomyces coelicolor TR:Q9ZBQ8 (EMBL; FT AL034447) 50S ribosomal protein L32 SC7A1.15 (57 aa), fasta FT scores opt: 165 z-score: 258.9 E(): 4.6e-07 82.1% identity FT in 28 aa overlap." FT /db_xref="GOA:Q9RL50" FT /db_xref="InterPro:IPR002677" FT /db_xref="UniProtKB/Swiss-Prot:Q9RL50" FT /protein_id="CAB56666.1" FT /translation="MAVPKRRMSRSNTRHRRAQWKASTPNLVPVTVDGVTLRVPRHLVP FT AYRRGLLRPEI" FT CDS complement(158670..159695) FT /transl_table=11 FT /gene="SCO0437" FT /gene_synonym="SCF51A.15c" FT /product="conserved hypothetical protein SCF51A.15c" FT /note="SCF51A.15c, hypothetical protein, len: 341 aa; FT similar to TR:Q9A8Z7 (EMBL:AE005797) Caulobacter crescentus FT hypothetical protein CC1198, 331 aa; fasta scores: opt: 855 FT Z-score: 977.0 E(): 8.7e-47; 45.181% identity in 332 aa FT overlap" FT /db_xref="UniProtKB/TrEMBL:Q9RL49" FT /protein_id="CAB56667.1" FT /translation="MPLSTHAARFAQLALANITREYPNFPAHLITSADERPEPRSLHPA FT FYGAYDWHSSVHMHWLLVRLLRRHGGTSALPGTEEAVAALDRHLTPGNLATEAAYLRER FT PSFERPYGWAWLLALAAECRALGGPEGQRWAGALEPAVDAVDALLADWLPKATYPVRHG FT NHPNSAFALGLALDSGELPAGTERAVRERLLSWFADDHDAPAHWEPSGQDFLSPALTEA FT DAMRRVLAPDRLARWLDRFLPGLGTGARCALLEVPVVSDHADPQIGHLLGLTLSRAAAL FT RALADALPDGPVRARLDKAAGAHLTAGLPAVERGDFTTDHWLATFAALALDPVAPPAPR FT H" FT CDS complement(159695..160345) FT /transl_table=11 FT /gene="SCO0438" FT /gene_synonym="pcp" FT /product="pyrrolidone-carboxylate peptidase (EC 3.4.19.3)" FT /note="SCF51A.16c, pcp, pyrrolidone-carboxylate peptidase FT (EC 3.4.19.3), len: 216 aa. Highly similar to many e.g. FT Bacillus subtilis SW:PCP_BACSU (EMBL; X66034) FT pyrrolidone-carboxylate peptidase (EC 3.4.19.3) FT (5-oxoprolyl-peptidase) (pyroglutamyl-peptidase I) (PGP-I) FT (pyrase)(215 aa), fasta scores opt: 741 z-score: 820.9 FT E(): 0 52.3% identity in 214 aa overlap. Contains a Pfam FT match to entry PF01470 Peptidase_C15, Pyroglutamyl FT peptidase and a Prosite hit to PS01334 FT Pyrrolidone-carboxylate peptidase cysteine active site" FT /db_xref="GOA:Q9RL48" FT /db_xref="HSSP:1AUG" FT /db_xref="InterPro:IPR016125" FT /db_xref="UniProtKB/Swiss-Prot:Q9RL48" FT /protein_id="CAB56668.1" FT /translation="MTRVLITGFAPFGGERVNPSWQAASLVAAEPPAGLAVTAAELPCV FT FGESLDALRDAIRADNPDLVLCLGQAGGRPGVTVERVGINVDDARIPDNAGGQPIDEPV FT VPDGPAAYFSTLPVKACVAAMREAGVPAAVSNTAGTFVCNHVAYGLGHLIATEFPHLRG FT GFAHVPWAPEQVPDGTAPALPPATVAHGLRALLAAAARTPAEQDLKVTEGATH" FT RBS complement(159706..159711) FT misc_feature complement(159737..160342) FT /note="Pfam match to entry PF01470 Peptidase_C15, FT Pyroglutamyl peptidase, score 333.00, E-value 3.3e-96" FT misc_feature complement(159914..159961) FT /note="PS01334 Pyrrolidone-carboxylate peptidase cysteine FT active site" FT RBS complement(160352..160356) FT CDS complement(160393..161367) FT /transl_table=11 FT /gene="SCO0439" FT /gene_synonym="SCF51A.17c" FT /product="putative membrane protein" FT /note="SCF51A.17c, possible membrane protein, len: 324 aa. FT Contains a possible N-terminal signal sequence and multiple FT possible membrane spanning hydrophobic domains." FT /db_xref="InterPro:IPR009323" FT /db_xref="UniProtKB/TrEMBL:Q9RL47" FT /protein_id="CAB56669.1" FT /translation="MIKVEWLYWLIGLVFVVMAVQMAMDRSNPKRWTSAAFWGLLGLTF FT PYGTGVANATAGNGGWTLPAEPLGVAVLALIVLAGFNFLGKGVPVTTTGEQREAAAARL FT GNKIFVPALTIPLVAIVCASVLDESGLFETGKATLLGLGLGCVAALVVGMLVTGEKKLS FT VPIHSGRSMLEAMGSALLLPQLLAVLGSIFAAAGVGDQVGDIMNKVLPDDSKYFAVLAY FT CVGMFLFTVIMGNAFAAFPVMTAAIGWPVLIQQMHGNEPAVLAIGMLAGFAGTLCTPMA FT ANFNIVPATLLELKDQYGPIKAQLPTGIALLGCCTVIMALFAF" FT CDS complement(161364..162083) FT /transl_table=11 FT /gene="SCO0440" FT /gene_synonym="SCF51A.18c" FT /product="possible integral membrane protein" FT /note="SCF51A.18c, possible integral membrane protein, len: FT 239 aa. Contains multiple possible membrane spanning FT hydrophobic domains." FT /db_xref="InterPro:IPR010374" FT /db_xref="UniProtKB/TrEMBL:Q9RL46" FT /protein_id="CAB56670.1" FT /translation="MIVLLGVVVVILGFVTRRNPVLVVGVAGIVTGLLGKMNPLEVLAA FT FGRSFADSRSVTVYAIVLPVIGLLERYGLREQARHLIGRLGKLSAGRFLTVYLLVRQVT FT AAFGLNSIGGPAQTVRPLVAPMAEAAAERSTGAKLPDKLREKVRSYSASADTVGVFFGE FT DCFIAIGSILLITGFVNSTYHQDIEPTQLALWAIPLAVCAFLIHGARLLLMDKQLEREM FT AQAAAEHDLPLPEGAEK" FT CDS 162350..163102 FT /transl_table=11 FT /gene="SCO0441" FT /gene_synonym="SCF51A.19" FT /product="conserved hypothetical protein SCF51A.19" FT /note="SCF51A.19, unknown, len: 250 aa. Similar to FT hypothetical proteins e.g. Bordetella pertussis TR:O30444 FT (EMBL; AF006000) hypothetical 26.3 KD protein (252 aa), FT fasta scores opt: 742 z-score: 794.0 E(): 0 47.4% identity FT in 247 aa overlap." FT /db_xref="InterPro:IPR005501" FT /db_xref="UniProtKB/Swiss-Prot:Q9RL45" FT /protein_id="CAB56671.1" FT /translation="MIDLNADLGEGFGRWTLTDDDALLSVVTSANVACGFHAGDPSVMR FT RVCDLAAERGVRIGAQVSYRDLAGFGRRAMDVPSDELAAEVAYQIGALRVFAEAAGAPV FT AYVKPHGALYNRTVHDEGQARAVVAGVRLAGGALPVLGLPGSRLLTAAAEAGLTGVPEA FT FADRAYTAEGSLVPRSEAGSVVTDEDAVVRRALAFAVEGSVEAVDGTAVAVAARSLCVH FT GDTPNAARIAARVREALETAGVGIGAFA" FT CDS 163099..163857 FT /transl_table=11 FT /gene="SCO0442" FT /gene_synonym="SCF51A.20" FT /product="conserved hypothetical protein" FT /note="SCF51A.20, unknown, len: 252 aa. Similar to a number FT of hypothetical proteins e.g. Escherichia coli FT SW:YBGJ_ECOLI (EMBL; AE000174) hypothetical 23.9 KD protein FT in phrB-nei intergenic region (218 aa), fasta scores: opt: FT 477 z-score: 492.1 E(): 4.7e-20 43.5% identity in 214 aa FT overlap" FT /db_xref="InterPro:IPR003833" FT /db_xref="UniProtKB/TrEMBL:Q9RL44" FT /protein_id="CAB56672.1" FT /translation="MTDGRPLTARPAGRHALLVELRDAEHTAAFHAEVLRRRAAGALPP FT VTEVVPGARTVLLDGVPDPDALARRVADWQVPPVADDTGAVVEIPVRYDGPDLADVAAL FT WGVGPDEVGALHRSHAYRVAFCGFAPGFGYLTGLPPRLHVPRRSTPRTRVPAGAVALAG FT PYSAVYPRATPGGWQLIGTMPDPRPLWDPARERAALLTPGTRVRFVTADGTCAGPGTGT FT GTGTETGTGTGTETGSGDDPTAGTSPEAGA" FT RBS 163842..163846 FT CDS 163854..164711 FT /transl_table=11 FT /gene="SCO0443" FT /gene_synonym="SCF51A.21" FT /product="conserved hypothetical protein SCF51A.21" FT /note="SCF51A.21, unknown, len: 285 aa. Similar to a number FT of hypothetical proteins e.g. Mycobacterium tuberculosis FT TR:P95220 (EMBL; Z86089) hypothetical 32.2 KD protein (300 FT aa), fasta scores opt: 714 z-score: 663.0 E(): 1.4e-29 FT 45.3% identity in 289 aa overlap. Also similar in parts to FT Pseudomonas fluorescens TR:CAB48407 (EMBL; AJ243652) urea FT amidolyase homologue (1213 aa), fasta scores opt: 423 FT z-score: 390.1 E(): 2.3e-14 37.7% identity in 289 aa FT overlap" FT /db_xref="InterPro:IPR003778" FT /db_xref="UniProtKB/TrEMBL:Q9RL43" FT /protein_id="CAB56673.1" FT /translation="MTTRLTTVRAGALTTVQDAGRPGHAHLGVPRSGALDAPAMRLANR FT LLGNDPDTAVLETTLTGCALRPDRDVAAVVGGAPCAVTVDGRPAAWGAPVRVPAGSVLD FT VGTATGGVRSYVAVAGGIAAEPVLGSRSTDLLSGLGPTPLRDGDVLAVGAPARPAPPPV FT AAPWPGPPAELVLPVRPGPRADWFTPAALRTLTSAAYRVSPHSNRIGLRTEGPPLQRLS FT TGELPSEGMVLGAVQVPPDGRPVIFLHDHPTTGGYPVVAVVPEPALAAAAQAVAGTPVR FT FTLA" FT CDS complement(164698..165099) FT /transl_table=11 FT /gene="SCO0444" FT /gene_synonym="SCF51A.22c" FT /product="putative integral membrane protein" FT /note="SCF51A.22c, possible integral membrane protein, len: FT 133 aa. Contains possible membrane spanning hydrophobic FT domains." FT /db_xref="UniProtKB/TrEMBL:Q9RL42" FT /protein_id="CAB56674.1" FT /translation="MVSSSRARVAARDDPGRTRSAAAVSAVLVVGAGLALRALAAGEVA FT KYGGDALYTLLLFALVFAAAPRTAPAKAAALALAVSWGVEFLQLSDVPAHLARQSTAAR FT LVLGSTFNAPDLFWYAVGAATGWLAVRRA" FT CDS complement(165207..166502) FT /transl_table=11 FT /gene="SCO0445" FT /gene_synonym="SCF51A.23c" FT /product="putative secreted protein" FT /note="SCF51A.23c, possible secreted protein, len: 405 aa. FT Contains a possible N-terminal signal sequence." FT /db_xref="UniProtKB/TrEMBL:Q9RL41" FT /protein_id="CAB56675.1" FT /translation="MLTPSSRRRGSAPRRRPRTARALTGTVCLLALSGTTLAAAPAPAA FT DPVPPAPVSWRADLSRTGTDDVNVRYDAGALRVRDGSLSPASLGRDRGYASAVLDPHHV FT GRPVDRVTVDLDATVPDAAGVEVDVRGRAADGAWTEWRRAAPGAPAELPREVVDVQARL FT TLWNARGGPTAAVRALTLTADDAGTAPAEPAPATRAAAFSARVYATREGLVGHTTANGH FT VIGANDHFVALPSRRALSPNGSGQYSVQVCGPARCETAPVWDVGPWNTHDDHWNPSAQR FT EQWKDLPQGLPQAQAAYEDGYNGGRDEFGRQVANPAGIDLADGTFYNVGLNDNGWVTVT FT YLWTEGGGDTTSFPTWGTDVSVRQRATTDSTRVASLPGPTTVRVRCQVHGQLVDYDGYS FT NDAWSYLPDYGGYVSNIFIDVADSWLPGVPTC" FT CDS complement(166496..166861) FT /transl_table=11 FT /gene="SCO0446" FT /gene_synonym="SCF51A.24c" FT /product="hypothetical protein SCF51A.24c" FT /note="SCF51A.24c, unknown, len: 121 aa; similar to FT C-terminal of SCF51A.23C TR:Q9RL41 (EMBL:AL121596) putative FT secreted protein from Streptomyces coelicolor (431 aa) FT fasta scores; opt: 408, Z-score: 470.3, E(): 1.4e-18, FT 70.115% identity (70.115% ungapped) in 87 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9RL40" FT /protein_id="CAB56676.1" FT /translation="MTTGVRTTPAIRGRLRRTPRPGPGLGLLHGLARGDDGVTATPFVT FT RETDVSVRQQPTTDSARVARPPGPTSVRVACQVHGGLVEYDGYSNDAWSHLPDHGGYVS FT SIFIDVDDARPPGAPTC" FT RBS complement(166510..166514) FT RBS complement(166869..166874) FT RBS 166984..166988 FT CDS 166990..167436 FT /transl_table=11 FT /gene="SCO0447" FT /gene_synonym="SCF51A.25" FT /product="putative MarR-family regulatory protein" FT /note="SCF51A.25, possible MarR-family regulatory protein, FT len: 148 aa. Similar to many hypothetical proteins with FT similarity to the MarR family of transcriptional regulators FT e.g. Mycobacterium tuberculosis SW: YZ08_MYCTU (EMBL; FT Z73101) hypothetical 15.6 KD protein CY31.08 (143 aa), FT fasta scores opt: 256 z-score: 328.8 E(): 5.9e-11 34.1% FT identity in 135 aa overlap. Contains a Pfam match to entry FT PF01047 MarR, MarR family" FT /db_xref="GOA:Q9RL39" FT /db_xref="InterPro:IPR000835" FT /db_xref="UniProtKB/TrEMBL:Q9RL39" FT /protein_id="CAB56677.1" FT /translation="MSENESPSPSAVQASREVRAVISRLRRRILKASEVEDLTLGQSSV FT LARLSDRGSITASELAAIEGVRHQSMTATVTALASMGLVERRPDPDDGRRLLITLTPEG FT VRRVEEGRQVRTEWLAERLQDRCTEEERRTVIAAMAVLERLNRD" FT misc_feature 167101..167415 FT /note="Pfam match to entry PF01047 MarR, MarR family, score FT 95.90, E-value 8.2e-25" FT CDS 167504..168909 FT /pseudo FT /transl_table=11 FT /gene="SCO0448" FT /gene_synonym="SCF51A.26" FT /product="putative transmembrane efflux protein FT (pseudogene)" FT /note="SCF51A.26, putative transmembrane efflux protein FT pseudogene, len: 86 aa. Similar to Streptomyces coelicolor FT TR:CAB42035 (EMBL; AL049754) putative transmembrane efflux FT protein (484 aa). Sequence contains a likely frame shift, FT within a well sequenced region, between bases FT 26483..26492." FT CDS 169153..170232 FT /transl_table=11 FT /gene="SCO0449" FT /gene_synonym="SCF51A.27" FT /product="possible secreted solute-binding lipoprotein" FT /note="SCF51A.27, possible secreted solute-binding FT lipoprotein , len: 359 aa. Weakly similar to many FT solute-binding proteins e.g. Streptomyces coelicolor FT TR:O69944 (EMBL; AL023862) putative secreted solute binding FT protein SC3F9.04 (348 aa), fasta scores opt: 231 z-score: FT 259.4 E(): 4.3e-07 23.2% identity in 366 aa overlap. FT Contains a possible N-terminal signal sequence and an FT appropriately positioned Prosite hit to, PS00013, a FT prokaryotic membrane lipoprotein lipid attachment site." FT /db_xref="InterPro:IPR013459" FT /db_xref="UniProtKB/TrEMBL:Q9RL38" FT /protein_id="CAB56679.1" FT /translation="MHKTPARRASVLVAAVSSLSLLTAGCGDGDGPVDDDTAANAKNAE FT ASPNAPTKTGLTVGFLPKQVNTPYFAVADRGGERAVESLGSTFKEVGTDQGADASGQVS FT HINGLTEQKADAIAVSALDPDALCDALKKAMAKGVKVVTYDSDTKPECRYAFVSPASAE FT DIAVRQLELLGEQTGYQGDIAILSAAQTATNQNAWISSIKRELEGPRYKEMRLVDVVYG FT DDEAEKSYQKAEELLREHGKLKGIISPTTNGIKAAAKYLSQSEYKGEVKLTGLGAPNDM FT RPYIKDGTVEAFLLWDPAKLGELAGHAAVALASGQITGREGQMFLAGDMGWFQLTGNGV FT ITLGEPTVFDAGNIDDYDF" FT misc_feature 169198..169230 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(170315..171304) FT /transl_table=11 FT /gene="SCO0450" FT /gene_synonym="SCF51A.28c" FT /product="putative integral membrane protein" FT /note="SCF51A.28c, possible integral membrane protein, len: FT 326 aa. Weakly similar to a number of sensory transduction FT histidine kinases e.g. Synechocystis sp. (strain PCC 6803) FT TR:P72791 (EMBL; D90900) (834 aa), fasta scores opt: 172 FT z-score: 187.7 E(): 0.0042 23.7% identity in 317 aa FT overlap. Contains multiple possible membrane spanning FT hydrophobic domains." FT /db_xref="InterPro:IPR007895" FT /db_xref="UniProtKB/TrEMBL:Q9RL37" FT /protein_id="CAB56680.1" FT /translation="MAAVVGIRAWPRPVVLTCATLLLAGCYYAAGRLGLSQQLTADGSV FT VTPIWPPTGLAVACLLLFGPWCVPGIALGALLVIVSLGAPGPEAAGIVVGNTAAPVCAW FT LLLRAVGFRLSLSRLRDGLALVFLGALAAMLISSCTGIGMLLLSGKLPTDHLGIVWLAW FT WVGDAMGVVLVTPLLLLLYRARLPPPSARWPEAAGLTAVVCVLVPLIMYSSVSVLFLAY FT PILIWSALRFQLAGGIPCALFVSVTATVVARQEAGSFGKLTDIETMMKLQAFNGTLGLT FT ALLLSAVISEQLNTRRSVERACHELVEALQHLNAGGSGAPGPPGGDGR" FT CDS complement(171355..172209) FT /transl_table=11 FT /gene="SCO0451" FT /gene_synonym="SCF51A.29c" FT /product="conserved hypothetical protein SCF51A.29c" FT /note="SCF51A.29c, unknown, len: 284 aa. Similar to the FT C-terminus of many hypothetical proteins e.g. Mycobacterium FT tuberculosis SW:Y07S_MYCTU (EMBL; Z75555) hypothetical 69.5 FT KD protein CY02B10.28C (653 aa), fasta scores opt: 390 FT z-score: 451.1 E(): 9.1e-18 33.5% identity in 263 aa FT overlap. In addition to Bacillus subtilis SW:RSBU_BACSU FT (EMBL; L35574) sigma factor SibG regulation protein RsbU FT (335 aa), fasta scores opt: 206 z-score: 243.6 E(): 3.3e-06 FT 24.3% identity in 185 aa overlap." FT /db_xref="GOA:Q9RL36" FT /db_xref="InterPro:IPR010822" FT /db_xref="UniProtKB/TrEMBL:Q9RL36" FT /protein_id="CAB56681.1" FT /translation="MFRKRPAPDGEELLARLASLTTRAKELAELRRSQVELAIALQRDM FT LPADLPAVPGIHLAACYSPAYAGLNVGGDWYDAFALPDGRIGLSVGDVQGHAIDAAAFM FT GQVRVGLRALASVTSEPGDLLACTNELLLSLNKDLFATCTFMRYDPATGLLESARAGHI FT PCVRATADGRAEVCRDEGGPPLGVLEGTEYPVTRYRLATGGVFVLVTDGVVEGPSLSVD FT EGLDRVVRLASLAAAVGMEADALAAAVLKNAELIGHEDDAAVLVVGHDGRGATRGLARG FT VTP" FT RBS complement(172216..172219) FT CDS 172415..173314 FT /transl_table=11 FT /gene="SCO0452" FT /gene_synonym="SCF51A.30" FT /product="putative SIR2-like regulatory protein" FT /note="SCF51A.30, possible SIR2-like regulatory protein, FT len: 299 aa. Similar to several Eukaryotic proteins e.g. FT Homo sapiens TR:AAD40852 (EMBL; AF083109) sirtuin type 4 FT (314 aa), fasta scores opt: 736 z-score: 829.3 E(): 0 FT 46.3% identity in 255 aa overlap. Also similar to several FT Prokaryotic proteins e.g. Archaeoglobus fulgidus TR:O30124 FT (EMBL; AE001098) transcriptional regulatory protein, SIR2 FT family (253 aa), fasta scores opt: 319 z-score: 364.7 E(): FT 5.9e-13 31.9% identity in 257 aa overlap." FT /db_xref="GOA:Q9RL35" FT /db_xref="HSSP:1ICI" FT /db_xref="InterPro:IPR003000" FT /db_xref="UniProtKB/Swiss-Prot:Q9RL35" FT /protein_id="CAB56682.1" FT /translation="MRMRPTLSWTPGADLPPGTTDLAPVADALRAGGVLVLSGAGISTE FT SGIPDYRGEGGSLSRHTPMTYQDFTAHPEARRRYWARSHLGWRTFGRARPNAGHRSVAA FT FGRHGLLTGVITQNVDGLHQAAGSEGVVELHGSLDRVVCLSCGVLSPRRELARRLEEAN FT AGFSPVAAGINPDGDADLTDEQVGDFRVVPCAVCGGVLKPDVVFFGENVPPRRVEHCRE FT LVRGASSLLVLGSSLTVMSGLRFVRQAAEAGKPVLIVNRDATRGDRLAVTRVALPLGPA FT LTTVADRLGLRVGDAATA" FT RBS 173445..173448 FT CDS 173458..174747 FT /transl_table=11 FT /gene="SCO0453" FT /gene_synonym="SCF51A.31" FT /product="probable secreted solute-binding lipoprotein." FT /note="SCF51A.31, probable secreted solute-binding FT lipoprotein, len: 429 aa. Weakly similar to many putative FT solute-binding proteins e.g. Bacillus subtilis FT SW:YURO_BACSU (EMBL; Z99120) hypothetical ABC transporter FT extracellular binding protein YurO (422 aa), fasta scores FT opt: 235 z-score: 270.1 E(): 1.1e-07 19.9% identity in 422 FT aa overlap. Contains a Pfam match to entry PF01547 FT SBP_bacterial_1, an appropriately positioned Prosite hit to FT PS00013, a prokaryotic membrane lipoprotein lipid FT attachment site and also contains a possible N-terminal FT signal sequence." FT /db_xref="GOA:Q9RL34" FT /db_xref="InterPro:IPR017909" FT /db_xref="UniProtKB/TrEMBL:Q9RL34" FT /protein_id="CAB56683.1" FT /translation="MRSSLTRRELLAAGSGLAAAAALPALSGCSSLASADSDPDTLVVH FT TQLGTTAPGSPTYLAAVDRFREENPGVKIKNLVNGDDLAQVYETSRLARKEADVVMVNL FT YDKTLAWTDVGATVDVKPYLDDWGLRGRVLPAALADWTDDEGRVRAFPYFATNWPVAYN FT RALLDRAGVDAIPTTGDQLIAAARKLRAKGIAPVTVGGNDWTGQKLLAQIIQTFLSQDE FT ARHVYSTGDFGVRGARLGIEYFAHLRDAGVFADKAQGLTSDSMTTQFNTEEAAVQSAMS FT SALAKVPEKVAGHTEVGGWPLADGAAHDGPTVIRAYTLIGFWISPNGVRKIEQVEKFLR FT FMYRPDVVARFVTESGRDMALRTDAVSTGFPLVGAAQRLGSEVSQVLLPDVYVPPAAAQ FT PLITATSTSFTRGTSPARVRAALESAYRSV" FT misc_feature 173512..173544 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature 173890..174729 FT /note="Pfam match to entry PF01547 SBP_bacterial_1, , score FT 33.50, E-value 4.7e-06" FT RBS 174837..174840 FT CDS 174848..175789 FT /transl_table=11 FT /gene="SCO0454" FT /gene_synonym="SCF51A.32" FT /product="binding-protein dependent transport protein" FT /note="SCF51A.32, probable binding-protein dependent FT transport protein, len: 313 aa. Similar to many including: FT Streptomyces coelicolor TR:CAB41203 (EMBL; AL049661) FT putative protein SCE134.05C (327 aa), fasta scores opt: FT 479 z-score: 546.7 E(): 4.3e-23 31.4% identity in 315 aa FT overlap. Contains a Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component and a Prosite hit to PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign. Contains multiple possible membrane spanning FT hydrophobic domains." FT /db_xref="GOA:Q9RL33" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9RL33" FT /protein_id="CAB56684.1" FT /translation="MTTLTTTPDGSAARRSVPPPSPAPAAGRRRQGGTVLAVPALVWYL FT VFMVGPLLAIFVIAALHWPGMLQPVSFAGLDNARVVLDDPVFWDAVRNTAVQLAVAVPV FT MIVCAFMLGYYVAQRPPGHRVIRYLLFIPGLISTPAKAMVFYAALSPDGLLNGGLESVG FT LGSLADAWLASPSTALACLIALDIWAGIGFTAVLFAARLGSVPDELGEAAQLDGAGHWR FT TMWSVHFPVIRDYVGVVTMLQFLWTLFGSAQHVLLLTQGGPGTSSTTLSFLVYQKAFIA FT ADLGYSQTVGVLLFLAGLVGLLTIRRVFRQNY" FT misc_feature 175448..175684 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 40.90, E-value 2.8e-08" FT misc_feature 175451..175537 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS 175804..176631 FT /transl_table=11 FT /gene="SCO0455" FT /gene_synonym="SCF51A.33" FT /product="putative binding-protein dependent transport FT protein" FT /note="SCF51A.33, putative binding-protein dependent FT transport protein, len: 274 aa. Similar to many e.g. FT Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) FT TR:O30833 (EMBL; AF018073) sorbitol/mannitol transport FT inner membrane protein (276 aa), fasta scores opt: 452 FT z-score: 556.9 E(): 1.2e-23 32.0% identity in 272 aa FT overlap. Contains a Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component. Contains multiple possible membrane spanning FT hydrophobic domains." FT /db_xref="GOA:Q9RL32" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9RL32" FT /protein_id="CAB56685.1" FT /translation="MKLGKRWLPAHILVWTYAVLLVVPLYYFLASAFKSNDEIFAHPFA FT PPSSLGLGNFRTAFESADLGLAVVNSALVTVFSLALTLLLAIPASFALARSTGRLAGVV FT EKVFSLGFLIPTFAALFPTFLLAAATGLFHTRIFMVLFLPATALPLSVVILVQFMRTIP FT PEMEEAARLDGASTFAVLRHVYTPMCLPGIATVLLLNFLTFWNEYLYSLVIIGPDPAQR FT TVQVALPTLKSITGTDYGVLTAGTVLTLVPVWLVYTLLQKRMQQALVSGAVKM" FT misc_feature 176275..176502 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 49.80, E-value 6e-11" FT CDS 176628..177671 FT /transl_table=11 FT /gene="SCO0456" FT /gene_synonym="SCF51A.34" FT /product="putative LacI family transcriptional regulator" FT /note="SCF51A.34, possible LacI family transcriptional FT regulator, len: 347 aa. Highly similar to several FT including: Escherichia coli SW:CYTR_ECOLI (EMBL; X03683) FT transcriptional repressor CytR (341 aa), fasta scores opt: FT 504 z-score: 574.2 E(): 1.3e-24 31.6% identity in 339 aa FT overlap and Streptomyces coelicolor TR:O86598 (EMBL; FT AL031514) putative transcriptional regulator SC2H4.15 (342 FT aa), fasta scores opt: 807 z-score: 915.3 E(): 0 44.4% FT identity in 333 aa overlap. Contains a Pfam match to entry FT PF00356 lacI, Bacterial regulatory proteins, lacI family, a FT Pfam match to entry PF00532 Peripla_BP_like, Periplasmic FT binding proteins and LacI family and a possible FT helix-turn-helix motif between residues 13..34 (+5.95 SD)." FT /db_xref="GOA:Q9RL31" FT /db_xref="HSSP:1PRU" FT /db_xref="InterPro:IPR001761" FT /db_xref="UniProtKB/TrEMBL:Q9RL31" FT /protein_id="CAB56686.1" FT /translation="MSISTERAGRRPTIKAVAAAAGVSTAAVSQAFNNKGRLSEATRRR FT ILDAALELGWSPSASAAALRNARTRSLALVVRRPTDVLGSDPHFSELITGIEGELAPRG FT YGLLLHLVSGHREENALYERLAAEGRVDGAVLTDARDDDARPALLARLGLPAVLLGSPD FT DTAVVPRVGLRDQGAGIAEAVAHLLGLGHRRVAYVSGPPELQHTRVRRAAFEGALREAG FT LRPFAVLPTDFSERRAVGATEALLDSADGPTAIVYANDSMAVCGIGTAQRAGLAVPRDV FT SVVGYDNLPLGSWLHPRLTTVDQQVQRVGAAAARMLLALCGEEVEDTALAERPRLVVRE FT STGPAPT" FT misc_feature 176655..176738 FT /note="Pfam match to entry PF00356 lacI, Bacterial FT regulatory proteins, lacI family, score 34.10, E-value FT 3.9e-08" FT misc_feature 176829..177566 FT /note="Pfam match to entry PF00532 Peripla_BP_like, FT Periplasmic binding proteins and LacI family., score 85.50, FT E-value 1.1e-21" FT RBS 177731..177735 FT CDS 177738..179672 FT /transl_table=11 FT /gene="SCO0457" FT /gene_synonym="SCF51A.35" FT /product="conserved hypothetical protein SCF51A.35" FT /note="SCF51A.35, unknown, len: 644 aa; " FT /db_xref="GOA:Q9RL30" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:Q9RL30" FT /protein_id="CAB56687.1" FT /translation="MRRHSAQLIHQPDVLPWLGANFWSRTGGPLMWRNYDPAVVREELR FT VLAGHGLNTTRSFFYWPDFHPEPDRVDDELCAWFEDFLDAHVETGMGTIPTFIVGHMSG FT ENWDPVWRGDRDLYEDVWMVGRQAWFVSRMARRFKDHPAVTGWLITNEMPGYGRIYQVD FT PPSTDVVTAWAQAMCNAVRATGATQPVSLGDGAWGIEVTGRDNGFSLRETAEYVDFVGP FT HVYRSDTDRPRQHYRAAFECELASVTGQPVVLEEFGLSTDTVSAANAGIFYRQTLHNSL FT LGGATGWLAWNNTDYDDLWDRSPYDHHPFEMHFGITDSTGAPKEPLRELAAFAGVLKAV FT DFPRCSRTDADAALVVPAFLERGYPYSRPADRPLIFTSLHQGYVTARAADLPVALTREA FT DGMPGEASLYLLPATRQLTTRTRRELARRAAEGATVYLSFCSGEHPVTRGPWFDDLDGL FT FGVELQLSYGVAEPIEDDVLELTFTEDFGDLRAGEVLRFPVAGNEDSRAYLPVEPRAGR FT VVAVDAHGRPALVVHETGAGRTVLSTYPLEHMAARTARVNPDVTQRLYGALAQLAGVRR FT PVTVADPHVSADVLVHADGRRFVWLVSQSPDPLVVRPAAEGKLHDLADGAPVQDVALDA FT YGVAVLELR" FT CDS 179669..181957 FT /transl_table=11 FT /gene="SCO0458" FT /gene_synonym="SCF51A.36" FT /product="Beta-glucosidase (EC 3.2.1.21)" FT /note="SCF51A.36, probable Beta-glucosidase (EC 3.2.1.21), FT len: 762 aa. Highly similar to many e.g. Escherichia coli FT SW:BGLX_ECOLI (EMBL; U15049) periplasmic Beta-glucosidase FT precursor (EC 3.2.1.21) (765 aa), fasta scores opt: 851 FT z-score: 896.9 E(): 0 32.2% identity in 773 aa overlap. FT Contains 2x Pfam matches to entry PF00933 Glyco_hydro_3, FT Glycosyl hydrolase family 3." FT /db_xref="GOA:Q9RL29" FT /db_xref="HSSP:1EX1" FT /db_xref="InterPro:IPR001764" FT /db_xref="UniProtKB/TrEMBL:Q9RL29" FT /protein_id="CAB56688.1" FT /translation="MTLPLYRDPAAPVPDRVRDLLGRMTLAEKVGQVNQRMYGWDAYER FT AGDGHRLTDAFRAEVAAFDGMGALYGLQRADAWSGVGFADGLDARDGARTAAAVQRYVM FT DHTRLGIPVLLVEEMPHGHQALDGTVLPVNLAVGATWDPDLYADAVAGAAAELRARGAH FT IALVSALDLVRDPRWGRSEECFSEDPYLAARMTEALVEGARRAGVAVVLKHFAGQGATV FT GGRNSAATELGPRELHEVHLAAARAGVAAGAAGVMAAYNEFDGLPCVANRYLLTDLLRT FT EWGFEGVVMADGTAVDRLVRLTGDPVSAGALALDAGCDLSLWDASFTRLGEAVERGLVS FT ESALDAAVARVLTLKFRLGLFEQPLPPARSETVELPDPAELGERIARASVTLLAHEGGV FT LPLSRAVRRIAVLGPNADSVAQQIGDYTAPQRPGGGITVLEGIRAAVAAGTEVVHDRGC FT ALVGDDVSGVPAAVALAAGSDVAVLVLGGSSARSPDTVFDANGAAVTGTGTPSGMTCGE FT GVDLADLALPPGQRALLTAVSATGTPVVVVLVQGRPHALTELDAPAAAVLSAWYPGPRG FT GRAVAEVLFGDAEPRGRLPVSVPRSAAQLPVYYNGKDHRYRGYADQSAGPLHAFGHGLS FT YTSVVYGAPRLSQARVGTRAPRLTCRVTVRNTGSRPAEETVQLYVRRLSGGSSWPRVRE FT LRGFVRLTIAPGEEAEAVFEVDRDTLASVGRDLRLAVEPGLVELETGPASDRTTGVRLE FT ITDSESNAT" FT misc_feature 179981..181045 FT /note="Pfam match to entry PF00933 Glyco_hydro_3, Glycosyl FT hydrolase family 3, score 274.20, E-value 6.7e-83" FT misc_feature 181214..181906 FT /note="Pfam match to entry PF00933 Glyco_hydro_3, Glycosyl FT hydrolase family 3, score 199.10, E-value 4.5e-60" FT CDS 182012..182791 FT /transl_table=11 FT /gene="SCO0459" FT /gene_synonym="SCF51A.37" FT /product="hypothetical protein SCF51A.37" FT /note="SCF51A.37, unknown, len: 259 aa. Similar to FT Mycobacterium tuberculosis SW:YX26_MYCTU (EMBL; Z74024) FT hypothetical 30.6 KD protein CY274.26C (283 aa), fasta FT scores opt: 268 z-score: 318.2 E(): 2.3e-10 28.9% identity FT in 263 aa overlap." FT /db_xref="GOA:Q9RL28" FT /db_xref="InterPro:IPR007037" FT /db_xref="UniProtKB/TrEMBL:Q9RL28" FT /protein_id="CAB56689.1" FT /translation="MFRARVVRTRRVSPSMQRVTVTGPGLGGFPWLGYDHWFRLFLQLP FT HQRDLRLPEFTGSQWWQPYLAIPEDERPHCANYSVADYRRAAAELDIDFVVHRGPTGEV FT EGRAAIWACGARPGDALALLDQGVLFDCPRDASEVTVVADETGLPATASIMRSLPEGTV FT GRLIQEIPTDADRRELNAPAGVTVSWVVRRDGTSVPGAAALRELRRLTRADASGYAFVV FT GESTLATEGRRHLHRLGLPKERITFSGFWKHEAMAAA" FT CDS complement(182810..183319) FT /transl_table=11 FT /gene="SCO0460" FT /gene_synonym="SCF51A.38" FT /product="hypothetical protein SCF51A.38" FT /note="SCF51A.38, unknown, len: 169 aa." FT /db_xref="InterPro:IPR010852" FT /db_xref="UniProtKB/TrEMBL:Q9RL27" FT /protein_id="CAB56690.1" FT /translation="MTDRAAEDVLLELLNTTPVVRGSVSDALGTPAEGRAWARGHGGTG FT SDEEAAHLVAVRDALQDVVRGRRDPACLGGFLHGVSRLPVIEDGGLRWVLQVPDAHRLA FT VELVLTWAHVEEARPGRLKPCGNPECRRFLLDRSKPNSARWCSMAECGNRMKARRHYQR FT AKGPQA" FT CDS 183456..184325 FT /transl_table=11 FT /gene="SCO0461" FT /gene_synonym="SCF76.01" FT /gene_synonym="SCF51A.39" FT /product="putative hydrolase" FT /note="SCF76.01, possible hydrolase, partial CDS, len: >228 FT aa. Similar to several hypothetical proteins e.g. from FT Saccharomyces cerevisiae SW:YN93_YEAST (EMBLL:Z71679) (290 FT aa), fasta scores opt: 609 z-score: 749.0 E():0 42.4% FT identity in 229 aa overlap. Also weakly similar to FT Xanthobacter autotrophicus SW:HALO_XANAU (EMBL:M26950) FT haloalkane dehalogenase (EC 3.8.1.5) (310 aa), fasta scores FT opt: 151 z-score: 190.4 E():0.003 22.9% identity in 231 aa FT overlap. Contains a Pfam match to entry PF00561 FT abhydrolase, alpha/beta hydrolase fold" FT /note="SCF51A.39, possible hydrolase, partial CDS, len: FT >113 aa. Highly similar to Saccharomyces cerevisiae (Bakers FT yeast) SW:YN93_YEAST (EMBL; Z71679) hypothetical 32.8 KD FT protein in BIO3-HXT17 intergenic region. In addition to FT being similar to many dehalogenases e.g. Mycobacterium FT tuberculosis SW:YU14_MYCTU (EMBL; Z77163) putative FT haloalkane dehalogenase (EC 3.8.1.5) (300 aa), fasta scores FT opt: 222 z-score: 292.5 E(): 6.2e-09 37.0% identity in 100 FT aa overlap" FT /db_xref="GOA:Q8CK57" FT /db_xref="HSSP:1EHY" FT /db_xref="InterPro:IPR000073" FT /db_xref="UniProtKB/TrEMBL:Q8CK57" FT /protein_id="CAD55442.1" FT /translation="MSVAVHHRTATVDGLDVFYREAGDPRAPAVVLLHGFPTSSHMFRG FT LIPKLADTYHVIAPDMIGFGYSAMPTVDAFDYSFDSLTDVTVGLLDQLGVERFAVYVQD FT YGAPVAWRIATRTPHRVTAIVTQNGNGYTDGFVKDFWDGLFAYTDDPTPETEAPARAAL FT SPGMVRWQYLNGVRDRSLVSPDTWSLDLALLDRPGNDAVQLTLFRDYPTNVGLYPRLQQ FT YFRDTRVPLLAVWGANDEIFGPDGARAFRRDLPDAEIHLLDTGHFALETHLEEITGHMR FT DFLARAGK" FT misc_feature 183639..184307 FT /note="Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold, score 56.90, E-value 4.4e-13" FT CDS complement(184338..185267) FT /transl_table=11 FT /gene="SCO0462" FT /gene_synonym="SCF76.02c" FT /product="putative oxidoreductase" FT /note="SCF76.02c, possible oxidoreductase, len: 305 aa. FT Similar to many hypothetical proteins e.g. Pyrococcus FT horikoshii SW:APBA_PYRHO (EMBL; AP000006) probable FT 2-dehydropantoate 2-reductase (EC 1.1.1.169) (ketopantoate FT reductase) (KPA reductase) (301 aa), fasta scores opt: 359 FT z-score: 419.9 E(): 4.9e-16 26.5% identity in 291 aa FT overlap and Streptomyces coelicolor TR:Q9ZBV6 FT (EMBL:AL034443) putative oxidoreductase SC4B5.12C (323 aa), FT fasta scores opt: 233 z-score: 274.7 E(): 6.1e-08 32.0% FT identity in 322 aa overlap." FT /db_xref="GOA:Q9RJH2" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RJH2" FT /protein_id="CAB56722.1" FT /translation="MRIAVIGAGGVGGYFGARLAAAGNEVTFVARGGHLAAIRRSGLVV FT HSPLGELRTSPDSVVASISELGPTDLVLVAVKLWDTQAVAEELRTSPAHGAPVLSLQNG FT VHKDDVLRGRLTDEQVLGGVCFISAFIEEPGVVRHNGPLQKVVLGPYRSGSTATVRAVL FT AAFRDAGIDAEGSDDIERAIWEKFVFLVGLSATTATVRQPVGVVRANERSRRLLYEVMA FT ETVAVAQASGVRLDSGFAEDRLAFCDTLPAAMTSSMHNDLEKGNRLELPWLSGGVVDLA FT DRLDVPVPRNRTVADILAPYVLGRPAGS" FT CDS 185318..185932 FT /transl_table=11 FT /gene="SCO0463" FT /gene_synonym="SCF76.03" FT /product="conserved hypothetical protein SCF76.03" FT /note="SCF76.03, unknown, len: 204 aa; similar to TR:Q9L1U0 FT (EMBL:AL138851) SCE59.14C hypothetical protein from FT Streptomyces coelicolor (196 aa) fasta scores; opt: 357, FT Z-score: 418.9, E(): 1.1e-15, 37.433% identity (40.230% FT ungapped) in 187 aa overlap." FT /db_xref="InterPro:IPR010852" FT /db_xref="UniProtKB/TrEMBL:Q9RJH1" FT /protein_id="CAB56723.1" FT /translation="MDAVQHQPPRTRVTAQLRALRFDAGTLCLNLVATVGRRPGVPVER FT MGDAERLEAWCRGVGLTLADGYDPRDVLSSLHALRAAAHDIASGALDAHRPRQESVDLV FT NLLARPAPPAPRLEVTADGAWVAEGRRALSKEALLSLVARDLIDLMTDEARRSRLAACA FT SEVCRMLCLDSGGGRPRKWCSMRRCGNRAKAAGRRLRESAP" FT CDS complement(185973..187670) FT /transl_table=11 FT /gene="SCO0464" FT /gene_synonym="SCF76.04c" FT /product="putative integral membrane protein" FT /note="SCF76.04c, possible integral membrane protein, len: FT 565 aa. Similar in parts to many hypothetical proteins e.g. FT Streptomyces lividans TR:O86875 (EMBL; U22894) hypothetical FT 57.9 KD protein (547 aa), fasta scores opt: 689 z-score: FT 806.6 E(): 0 41.7% identity in 439 aa overlap and FT Streptomyces coelicolor TR:O86807 (EMBL; AL031031) putative FT regulatory protein (916 aa), fasta scores opt: 329 z-score: FT 381.2 E(): 7.1e-14 26.5% identity in 582 aa overlap. FT Contains a Pfam match to entry PF01590 GAF, GAF domain and FT possible membrane spanning hydrophobic domains." FT /db_xref="GOA:Q9RJH0" FT /db_xref="InterPro:IPR010822" FT /db_xref="UniProtKB/TrEMBL:Q9RJH0" FT /protein_id="CAB56724.1" FT /translation="MSGIPEGEAGAALRALLTDSVVGLAVWDTGLRCVWVNDALERYDG FT IARERRLGRRPRESLTGDTGELEALVRRVLATGRCVTGREYRVPTAPDSRRDRAFSASF FT VRLHDDGGHILGVCMLMLVVTDRRWAGDRLAVVSEAGTRVGTTLDVMRTAQELADFTVP FT LIADYVTVDLTEAVRLGEEPLDRLGRSQGRVPKFRRAGRASVHAGSPESLWLNGEVVYV FT PETSPFMQVLSSGRPLLHPVLDPSHEAWLADDPARAAKIREFGMHSLLILPIHARGVLL FT GVAVFVRTSNPTPFDDNDRLLAEELVARAALSLDNARRYTREHNTALALQRSLLPRRVH FT GGTAMEVAARYLPADAEEGVGGDWFDVIGLPGGRLALVVGDVVGHGVNAAATMGRLGMA FT IRTLADLDLPPGEVLTRLDRTFIRLTEDEEEGGGEVATMSATCVYAVYDPATRTCALAL FT AGHPPPAVVHRGGDCSFPDLPHGLPLGVGLLPFPTAELELPAGSLLALFTDGLVEERDQ FT DIEVGLRRVGRALTRGASSLEDLGTAVIGTLPATPPPDDVTLLLARGL" FT misc_feature complement(186714..187388) FT /note="Pfam match to entry PF01590 GAF, GAF domain, score FT 38.80, E-value 1.3e-07" FT CDS complement(187684..188514) FT /transl_table=11 FT /gene="SCO0465" FT /gene_synonym="SCF76.05c" FT /product="non-heme chloroperoxidase (chloride peroxidase)" FT /note="SCF76.05c, non-heme chloroperoxidase (chloride FT peroxidase), len: 276 aa. Identical to Streptomyces FT lividans SW:PRXC_STRLI (EMBL; U02635) non-heme FT chloroperoxidase (EC 1.11.1.10) (chloride FT peroxidase)(CPO-L) (chloroperoxidase L) (275 aa), fasta FT scores opt: 1866 z-score: 2162.6 E():0 99.3% identity in FT 275 aa overlap. Contains a Pfam match to entry PF00561 FT abhydrolase, alpha/beta hydrolase fold." FT /db_xref="GOA:Q9RJG9" FT /db_xref="HSSP:1A88" FT /db_xref="InterPro:IPR000639" FT /db_xref="UniProtKB/TrEMBL:Q9RJG9" FT /protein_id="CAB56725.1" FT /translation="MGTVTTSDGTNIFYKDWGPRDGLPVVFHHGWPLSADDWDNQMLFF FT LSHGYRVIAHDRRGHGRSDQPSTGHDMDTYAADVAALTEALDLRGAVHIGHSTGGGEVA FT RYVARAEPGRVAKAVLVSAVPPVMVKSDTNPDGLPLEVFDGFRAALAANRAQFYIDVPS FT GPFYGFNREGATVSQGLIDHWWLQGMMGAANAHYECIAAFSETDFTDDLKRIDVPVLVA FT HGTDDQVVPYADAAPKSAELLTNATLKSYEGLPHGMLSTHPEVLNPDLLAFVKS" FT misc_feature complement(187693..188367) FT /note="Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold, score 124.80, E-value 1.6e-33" FT CDS 188618..189601 FT /transl_table=11 FT /gene="SCO0466" FT /gene_synonym="SCF76.06" FT /product="araC family transcriptional regulator" FT /note="SCF76.06, probable araC family transcriptional FT regulator, len: 327 aa. Highly similar to many including FT the Streptomyces coelicolor hypothetical regulators: FT TR:CAB40696 (EMBL; AL049587) SC5F2A.29 (325 aa), fasta FT scores opt: 857 z-score: 962.2 E():0 45.8% identity in 323 FT aa overlap and TR:CAB46927 (EMBL; AL096822) SCGD3.05 (334 FT aa), fasta scores opt: 617 z-score: 694.7 E(): 2.4e-31 FT 38.6% identity in 332 aa overlap. In addition to FT Streptomyces lividans SW:YCP1_STRLI (EMBL; U02635) FT hypothetical protein in CPOL 5'region (ORF1) (fragment) FT (141 aa), fasta scores opt: 908 z-score: 1024.0 E():0 FT 99.3% identity in 141 aa overlap. Contains a Pfam match to FT entry PF00165 HTH_2, Bacterial regulatory helix-turn-helix FT proteins, araC family. There are two possible FT helix-turn-helix motifs located between residues 237..258 FT (+3.99 SD) and 301..322 (+2.58 SD). Note that the FT translational start site may be 'M' residue 6." FT /db_xref="GOA:Q9RJG8" FT /db_xref="InterPro:IPR018060" FT /db_xref="UniProtKB/TrEMBL:Q9RJG8" FT /protein_id="CAB56726.1" FT /translation="MAEEAMTAGPHRVVVLVFDGMKLLDLSGPAEVFSEANRFGADYRL FT SIVSADGSPVRSSIGMLVPADTDARAAAAHDTLVVVGGDALPGSPVDPVLGAAAKELAE FT RAGRVASVCTGAFVLGAAGLLEGRRATTHWQHTATLARRCPSTRVEADALFVKDGSTYT FT SAGVTAGIDLALALLEEDHGPGLARQVARSLVVYMQRAGGQSQFSASLQGPAPRTPVLR FT LVQEAVQGDPTADHGLEALAARVRVSPRHLTRMFRAELDTTPMKYVELIRFDMAKALLD FT AGHNATEAATRSGFSSYESLRRAFARHLGLSPIRYQQRFATTSRES" FT misc_feature 189320..189577 FT /note="Pfam match to entry PF00165 HTH_2, Bacterial FT regulatory helix-turn-helix proteins, araC family, score FT 50.60, E-value 3.5e-11" FT CDS 189614..190357 FT /transl_table=11 FT /gene="SCO0467" FT /gene_synonym="SCF76.07" FT /product="conserved hypothetical protein SCF76.07" FT /note="SCF76.07, unknown, len: 247 aa; similar to TR:Q98LL0 FT (EMBL:AP002996) MLR0982 protein from Rhizobium loti FT (Mesorhizobium loti) (215 aa) fasta scores; opt: 410, FT Z-score: 484.9, E(): 2.2e-19, 33.178% identity (33.649% FT ungapped) in 214 aa overlap." FT /db_xref="GOA:Q9RJG7" FT /db_xref="InterPro:IPR006674" FT /db_xref="UniProtKB/TrEMBL:Q9RJG7" FT /protein_id="CAB56727.1" FT /translation="MTGSEGFVAIGQRTRSGRPAQGGTDTTGNRPGRTTMTETIAGIGI FT PDSSLAREATELVRDTTPPLIFHHSRRVYLFGSLQAAALGLRPDPELLYVAALFHDTGL FT VPPYRGDDQRFEMDGADQARAFLLAHGVPEADADTVWTAVALHTTPEVPYKLAPEIAAT FT TAGVETDVLGLHLARITRAEIDAVTAAHPRPDFKKQILQAFTDGFGHRPQTTFGTVNAD FT VLEHFLPGFRRTDFVEVIENSAWPE" FT CDS complement(190373..191350) FT /transl_table=11 FT /gene="SCO0468" FT /gene_synonym="SCF76.08c" FT /product="conserved hypothetical protein SCF76.08c" FT /note="SCF76.08c, unknown, len: 325 aa. The N-terminus is FT highly similar to several PIRIN proteins e.g. Alcaligenes FT eutrophus TR: AAD21775 (EMBL; J05278) PIRIN (187 aa), fasta FT scores opt: 446 z-score: 495.3 E(): 3.1e-20 49.7% identity FT in 149 aa overlap. Also similar to several hypothetical FT proteins e.g. Mycobacterium tuberculosis TR:O07425 (EMBL; FT Z97050) hypothetical 26.3 KD protein (244 aa), fasta scores FT opt: 269 z-score: 301.6 E(): 1.9e-09 32.7% identity in 217 FT aa overlap." FT /db_xref="InterPro:IPR003829" FT /db_xref="UniProtKB/TrEMBL:Q9RJG6" FT /protein_id="CAB56728.1" FT /translation="MSNTETHPAEVRCGAGEEGAPAAGVEILTARDVPLGGPRAMTVRR FT TLPQRARTLIGAWCFADHYGPDEVSRSGGMDVAPHPHIGLQTVSWLFSGEIEHRDSVGS FT HALVRPGEVNLMTGGHGISHSEVSTPDTTVLHGVQLWVALPSEHRDTAPAFQHHVPAPV FT ALDGGEARVFLGSLAGDTSPVGTFTPLLGAEVTLAPGATVTLDVDPGFEHGVLVDSGDV FT RLDGTVVRPAELAYAAPGRRTLALTNAASGAARLVVLGGPPFPEEIVMWWNFVGRTHDE FT IAAARADWENEAERFGRVEGYPGDRLPAPALPNATLSPRRNPRP" FT RBS 191437..191441 FT CDS 191451..191972 FT /transl_table=11 FT /gene="SCO0469" FT /gene_synonym="SCF76.09" FT /product="hypothetical protein SCF76.09" FT /note="SCF76.09, unknown, len: 173 aa. Weakly similar in FT parts to Bacillus subtilis TR:P96684 (EMBL; AB001488) YDFG FT protein (147 aa), fasta scores opt: 260 z-score: 329.6 FT E(): 5.3e-11 35.1% identity in 111 aa overlap." FT /db_xref="InterPro:IPR003779" FT /db_xref="UniProtKB/TrEMBL:Q9RJG5" FT /protein_id="CAB56729.1" FT /translation="MTQTPVRADAGAPGSTGSTGERRVFVDKQSPEAYAALRATAEAVR FT GVAEAAGLDRILVELVNIRVSQLNACAYCLNAHTRAALRGGETTQRLGVLPAWRDTELF FT SPRERAALALAEATTHPADAGAQSTAYAEARGVLSDDEISAVIWVAISINAFNRVSVLS FT KHPVRGAPRA" FT CDS 191983..192891 FT /transl_table=11 FT /gene="SCO0470" FT /gene_synonym="SCF76.10" FT /product="putative hydrolase" FT /note="SCF76.10, possible hydrolase, len: 302 aa. Weakly FT similar to hydrolases e.g. the N-terminal, domain of FT Streptomyces coelicolor TR:O86608 (EMBL:AL031155) FT 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone FT decarboxylase (449 aa), fasta scores opt: 387 z-score: FT 428.9 E(): 1.6e-16 33.7% identity in 258 aa overlap. FT Contains a Pfam match to entry PF00561 abhydrolase, FT alpha/beta hydrolase fold." FT /db_xref="GOA:Q9RJG4" FT /db_xref="InterPro:IPR000073" FT /db_xref="UniProtKB/TrEMBL:Q9RJG4" FT /protein_id="CAB56730.1" FT /translation="MRPEPLERGHSYKTRVRHRAHPCGMSQYDARFPHGMHVVDDGPPQ FT APPVLLIHGSGASGASWNRVVPALAEQRRVLRVDLPGCGKSPPTPSYDVPLQAGRLAAL FT LDDLGLRSVTVAGHSSGGYVATALAERRPDLVGALALVSTGPNPDALLPQPMILRLLLA FT PPFGPLLWPRRTDAMLRKAIAATAAGPVEVPAEMVDDVRGISYRSFRTVARGNTAYLAE FT RGVPERLAALTVPVLVLFGAADPRWDPSSAHRYEAVPNARLELLPGVGHLPPLEAPGPT FT GELLLGLTARGADLPAAGPET" FT misc_feature 192199..192849 FT /note="Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold, score 77.30, E-value 3.1e-19" FT CDS 192901..193881 FT /transl_table=11 FT /gene="SCO0471" FT /gene_synonym="SCF76.11" FT /product="putative araC family transcriptional regulator" FT /note="SCF76.11, possible araC family transcriptional FT regulator, len: 326 aa. Weakly similar to the DNA-binding FT domains of other transcriptional regulators e.g. FT Escherichia coli SW:ARAC_ECOLI (EMBL; V00256) arabinose FT operon regulatory protein (292 aa), fasta scores opt: 130 FT z-score: 151.4 E(): 0.45 28.2% identity in 163 aa overlap. FT Contains a Pfam match to entry PF00165 HTH_2, Bacterial FT regulatory helix-turn-helix proteins, araC family. The FT putative helix-turn-helix motif is located between residues FT 197..218 (+2.74 SD). Also contains a possible membrane FT spanning hydrophobic domain." FT /db_xref="GOA:Q9RJG3" FT /db_xref="InterPro:IPR018060" FT /db_xref="UniProtKB/TrEMBL:Q9RJG3" FT /protein_id="CAB56731.1" FT /translation="MLSTETPTDPSAPAPAVAPTGAPPDWSIVDVAVPRPSVRLAGVAM FT AGFSQHVSAFVDMAMVAHPSVTLLIDLSDGDGILYSARDRHGHGSFVVGLAPGDLRAAG FT RVGTCLQIRLEPAVAAAVLGPSAGLGGRVESFEDVWGREAGRVQDELRTAGSWDERFAV FT AADVLRRRTADRPPVDPEVAHTWRTTLAGRGRVRVEGLAEEVGWSRKRLSARFHAQLGI FT TPKRAARLVRFDHAAHLLAAGLAPASVAFESGYADQSHLHREVKAFTGLTPTAVAGAPW FT LAIDDVAWPGSSPARSVSAAGSAPRRMARPGRAWNRGRTAWTDAH" FT misc_feature 193483..193740 FT /note="Pfam match to entry PF00165 HTH_2, Bacterial FT regulatory helix-turn-helix proteins, araC family, score FT 46.50, E-value 5.7e-10" FT CDS complement(194055..195263) FT /transl_table=11 FT /gene="SCO0472" FT /gene_synonym="SCF76.12c" FT /product="putative secreted protein" FT /note="SCF76.12c, possible secreted protein, len: 384 aa. FT Contains a possible N-terminal signal sequence." FT /db_xref="UniProtKB/TrEMBL:Q9RJG2" FT /protein_id="CAB56732.1" FT /translation="MNTSIRNRAVTGTALALAVSAVLTACGGDTSSSDATSKGGGSTPS FT ATPAASVQDPLVATFDGGLYILDGKSLELTRTIDLPGFNRVNPAGDKDHVVVSTDRGFR FT LLNATRQALTDIEYKGAKPGHVVRHAGKTVLFTDGTGEVNVFAPGDLGTGEKPDGRTYR FT SAEAHHGVAIELSDGRLLTTLGDEEKRTGALVVDKDGKEIARSENCPGVHGEAAARGEA FT IALGCEDGVLIYKDGRFTKVDAPDDYGRTGNQAGSDASPVLLGDYKSDPDAELERPTRI FT SLIDTGTAKLRLVELGTSYSFRSLARGPHGEALVLGTDGAIHVIDPDKGTVEKKIPAVG FT QWQEPLDWQQARPTLFVRGHTAYVSEPGKKAVHAIDLESGRKRTSVTLPQGTNELSGTV FT AGH" FT CDS complement(195260..196249) FT /transl_table=11 FT /gene="SCO0473" FT /gene_synonym="SCF76.13c" FT /product="putative solute-binding lipoprotein" FT /note="SCF76.13c, possible solute-binding lipoprotein, len: FT 329 aa. Similar to many e.g. Streptococcus parasanguis FT SW:ADHS_STRPA (EMBL; M26130) adhesin B precursor FT (saliva-binding protein) (309 aa), fasta scores opt: 354 FT z-score: 399.1 E(): 7.2e-15 23.7% identity in 317 aa FT overlap. Contains an appropriately positioned Prosite hit FT to PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site, a Pfam match to entry PF01297 FT Lipoprotein_4, Adhesion lipoprotein and a possible FT N-terminal signal sequence." FT /db_xref="GOA:Q9RJG1" FT /db_xref="InterPro:IPR006127" FT /db_xref="UniProtKB/TrEMBL:Q9RJG1" FT /protein_id="CAB56733.1" FT /translation="MRGTVRTRIRVARLRRLLVGLLALVTAATATACSATDEQPRIVVT FT TNILGDITRQVVGDQAEVTVLMKPNADPHSFGLSAVQAAQLERADLVVFNGLGLEENVL FT RHVDAAREAGVATFEVGRAVDPLTFHSGDDGGPEGESGRPDPHFWTDPDRVRTAAGLIT FT DRVSEHVTGVDHDAIRANAAEYDEQLADLTAFMEKSFDRVPEDRRNLVTNHHVFGYLAD FT RFGFRVIGAVIPSGTTLASPSSSDLRSLTRAMERAGVRTVFADSSRPKRLAEVLSTELG FT DGVRVVELYSESLTAENEGAATYLQMMRANTTALTDGLTVGSPKGTHS" FT RBS complement(195272..195277) FT misc_feature complement(195290..196189) FT /note="Pfam match to entry PF01297 Lipoprotein_4, Adhesion FT lipoprotein, score 134.20, E-value 2.4e-36" FT misc_feature complement(196151..196183) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(196246..197493) FT /transl_table=11 FT /gene="SCO0474" FT /gene_synonym="SCF76.14c" FT /product="putative lipoprotein" FT /note="SCF76.14c, possible lipoprotein, len: 415 aa. FT Contains an appropriately positioned Prosite hit to PS00013 FT Prokaryotic membrane lipoprotein lipid attachment site and FT a possible N-terminal signal sequence." FT /db_xref="UniProtKB/TrEMBL:Q9RJG0" FT /protein_id="CAB56734.1" FT /translation="MEPTVRTHPTRRLPTALVLTAALLATGCSEQSDDGREPAATESSG FT TPHGYVEGAREAAEEQSRLILGDPGTGASRVLDLVTGKVHESEPVTGADGLSTDGRFGF FT FHTDRGTHVVDGGAWTVDHGDHVHYYRAAIRHVGDLPGGRGAEIRSDAAVTAATDPEGR FT TTLYDRTALEKGEVGPARTLDGVHAGAVVPYEEHLVALAGDDESAEVAVYDRSGRRVAS FT PDATCERPAGDAVTRRGVVLGCADGALLVSAEDGTFTAERIPYGQDVPEKERATAFRHR FT AGSDTLTAPAGERAVWVLDVTDRDWTRVRTTGPVLAANTAGEGSPLLVLESDGALHGYD FT IATGRHTARTEPLLTRTAKTPAGAAAPVVEVDRSRAYVNDRTGKRVYEIDYNDALRVAR FT SFDLDIAPGLMAETGR" FT misc_feature complement(197410..197442) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(197508..198359) FT /transl_table=11 FT /gene="SCO0475" FT /gene_synonym="SCF76.15c" FT /product="ABC transporter protein, integral membrane FT subunit" FT /note="SCF76.15c, probable ABC transporter protein, FT integral membrane subunit, len: 283 aa. Similar to many FT e.g. Escherichia coli SW:ZNUB_ECOLI (EMBL; AE000280) FT high-affinity zinc uptake system membrane protein ZnuB (261 FT aa), fasta scores opt: 442 z-score: 483.2 E(): 1.5e-19 FT 32.5% identity in 246 aa overlap. Contains a Pfam match to FT entry PF00950 ABC-3, ABC 3 transport family and multiple FT possible membrane spanning hydrophobic domains." FT /db_xref="GOA:Q9RJF9" FT /db_xref="InterPro:IPR001626" FT /db_xref="UniProtKB/TrEMBL:Q9RJF9" FT /protein_id="CAB56735.1" FT /translation="MDWLTAPFEVTFVQRALWGGILVSAICALAGTWVVLRGMAFLGDA FT MSHGLLPGVALAALLGGNLLLGAVASAAVMAAGVTALGRTPRLSQDTGIGLLFVGMLSI FT GVIIVSRSQSFAVDLTGILFGDVLAVREQDLLVLGGALLVALLVSVLGHRAFLALAFDP FT RKAHTLGLRPRLAHAVLLVLLGLAIVASFHIVGTLLVLGLLIAPPAAALPWARGVRGVM FT ALAALLGVTATFGGLLLSWHLSTAAGATVSAVAVALFFLSHTASGLRHLRTRPATPHPT FT VD" FT misc_feature complement(197562..198335) FT /note="Pfam match to entry PF00950 ABC-3, ABC 3 transport FT family, score 238.20, E-value 1.2e-67" FT RBS 198362..198366 FT CDS 198375..199133 FT /transl_table=11 FT /gene="SCO0476" FT /gene_synonym="SCF76.16" FT /product="ABC transport protein, ATP-binding subunit" FT /note="SCF76.16, ABC transport protein, ATP-binding FT subunit, len: 252 aa. Similar to many e.g. Haemophilus FT influenzae SW:FECE_HAEIN (EMBL; U32720) iron(III) dicitrate FT transport ATP-binding protein FecE homolog (306 aa), fasta FT scores opt: 375 z-score: 413.4 E(): 1.2e-15 37.3% identity FT in 185 aa overlap. Contains a Prosite hit to PS00211 ABC FT transporters family signature and PS00017 ATP/GTP-binding FT site motif A (P-loop)." FT /db_xref="GOA:Q9RJF8" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9RJF8" FT /protein_id="CAB56736.1" FT /translation="MKIMFNKSRPSPPAVPGRASGVRLTELCAGYPGRPVLRQLTCEIP FT ALAVTALVGPNGSGKSTLLGVLAGVIRPTSGDLHRDGERPPAFVPQRGAVADALPLTVR FT QTVEMGRWAERGPWRRLNRRDRLIVDSALDRLGIADLAPRQLGELSGGQRQRALVAQGL FT AQQSDLLLLDEPTTGLDPEARQRITALLTDLVADGVTVVHATHDLEAARSAEACLLLRA FT GTLAGQGRPGRVLTASALAEVWAVAGHAGP" FT misc_feature 198534..198557 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 198819..198863 FT /note="PS00211 ABC transporters family signature" FT RBS 199226..199229 FT CDS 199238..199630 FT /transl_table=11 FT /gene="SCO0477" FT /gene_synonym="SCF76.17" FT /product="conserved hypothetical protein" FT /note="SCF76.17, conserved hypothetical protein, len: 130 FT aa. Highly similar to several including: Bacillus subtilis FT TR:O32161 (EMBL; Z99120) YurT protein (127 aa), fasta FT scores opt: 494 z-score: 605.8 E(): 2.2e-26 58.6% identity FT in 128 aa overlap, Streptomyces coelicolor TR:CAB42950 FT (EMBL; AL049863) hypothetical 14.4 KD protein SC5H1.25C FT (131 aa), fasta scores opt: 221 z-score: 280.0 E(): 3.1e-08 FT 37.2% identity in 129 aa overlap and also weakly similar to FT some lyases e.g. Salmonella typhimurium SW:LGUL_SALTY FT (EMBL; U57364) lactoylglutathione lyase (EC 4.4.1.5) (135 FT aa), fasta scores opt: 101 z-score: 136.7 E(): 2.9 23.1% FT identity in 134 aa overlap" FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/TrEMBL:Q9RJF7" FT /protein_id="CAB56737.1" FT /translation="MKINLTSVFVDDQAHALRFYTETLGFLKKHDVPVGAGGDRWLTVV FT SPEAPDGTELLLEPSGHPAVAPYRTALAQDGIPAASFAVDDVRAEHDRLRSLGVHFTQE FT PMEMGAVTTAVLDDTCGNLIQIMQVR" FT CDS complement(199683..200807) FT /transl_table=11 FT /gene="SCO0478" FT /gene_synonym="SCF76.18c" FT /product="putative membrane protein" FT /note="SCF76.18c, possible membrane protein, len: 374 aa. FT Contains a possible membrane spanning hydrophobic domain." FT /db_xref="GOA:Q9RJF6" FT /db_xref="InterPro:IPR017909" FT /db_xref="UniProtKB/TrEMBL:Q9RJF6" FT /protein_id="CAB56738.1" FT /translation="MREEASETGAPFGRRTFMASAVVAAAASVPAAAPALAAGLPEAAA FT PGCRSVAHLLAVPESGRGVDWLREALQVAVALELATIPPYLCGWWSVGDRTSHVARLIR FT RIIGDEMYHMGVVCNLLVAVGGRPRITDAALAYPGPLPGGVREEVNVYLSGLNRPFVRD FT VMMAIEAPEVPLARGANNSPGIGHFYDGLLRAFRATAPPLSAGGQLSQRIGSDVLEPVT FT DLDGVERAVEIIKEQGEGTASSPEDAFGDDYPAHYYAFGEIYHGRQLRREDDGWRFTGA FT PVPFPDARPMARVPAGGWPGPSQRVGDLLDRFDTAYAKVLGTLEAAWAHGDARTLGSAV FT RTMRALEGPAVELMETGIPGGRGTYGPQFRPPGA" FT CDS complement(200952..201776) FT /transl_table=11 FT /gene="SCO0479" FT /gene_synonym="SCF76.19c" FT /product="putative phosphatase SCF76.19c" FT /note="SCF76.19c, putative phosphatase, len: 274 aa. Almost FT identical to Streptomyces lividans TR:O70034 (EMBL; FT AJ223365) Sbl1 gene (274 aa), fasta scores opt: 1764 FT z-score: 2005.4 E():0 97.1% identity in 274 aa overlap. FT Also weakly similar to many inositol monophosphatases e.g. FT Mycobacterium smegmatis TR:O51845 (EMBL; AF005905) inositol FT monophosphate phosphatase (276 aa), fasta scores opt: 299 FT z-score: 346.7 E(): 6e-12 33.1% identity in 269 aa overlap FT and Escherichia coli SW: SUHB_ECOLI (EMBL; M34828) FT extragenic suppressor protein SuhB (267 aa), fasta scores FT opt: 269 z-score: 313.0 E(): 4.6e-10 30.8% identity in 263 FT aa overlap." FT /db_xref="GOA:Q9RJF5" FT /db_xref="InterPro:IPR017955" FT /db_xref="UniProtKB/TrEMBL:Q9RJF5" FT /protein_id="CAB56739.1" FT /translation="MINLPVPHDETGARHDDTEVAIAAARAGAETVRARYGRRLTRFDK FT GGGDFATDADVAAEEAILGVIRAARPHDAICGEEGGRRGAADAARQWLVDPLCGTLNYA FT AGTMAVAVNVALRGGPAAVADPFGGEVLFTDGETARVRRDGHDTPLAPSAATRLVDVNL FT DPPFPGAPAFRAVDLIAHPGFVRRLRPRVLSTTLALAWVAAGKRAAYVTDGTGLTESVH FT FAAGIALCRAAGCVVTGVDGEPVGPVGRGLVAAADAGTHALLLSLIREGRPR" FT CDS 201780..202412 FT /transl_table=11 FT /gene="SCO0480" FT /gene_synonym="SCF80.01" FT /gene_synonym="SCF76.20" FT /product="hypothetical protein" FT /note="SCF80.01, unknown, partial CDS, len: >193 aa. FT Similar in parts to Streptomyces coelicolor TR:CAB53333 FT (EMBL;AL109974) hypothetical 34.2 KD protein SCF34.22 (326 FT aa), fasta scores opt:opt: 296 z-score: 300.2 E(): 2.4e-09 FT 40.5% identity in 148 aa overlap." FT /note="SCF76.20, unknown, partial CDS, len: >49 aa." FT /db_xref="UniProtKB/TrEMBL:Q8CK56" FT /protein_id="CAD55443.1" FT /translation="MQGNGRSFPGLRSTGPPDLPTSRPPGLPASGPTTPGDPGRGAGLL FT QEVPQEIPARQGRPVRRFPVAPVMTESGRPRVPTGSAMRPSTRSRSMDNRSSSSGVARP FT PAAYGTSPTMVLLYRPGAAWTADPYVLSPGRRSPLTLFAAEHFLGGISGYEAAETTDEN FT PAAHVAVVRRVPLAHLRHTLGVDSTDWTAARRTLAGTAHPLGRLEAE" FT repeat_region 201825..201877 FT /note="degenerate repeat region with 3x CCTCCCGA, 2x FT CCTCCCGG, 1x CCTCCGG." FT misc_feature 202356..203904 FT /note="99% identical to Streptomyces coelicolor FT EMBL:AB017013." FT RBS 202688..202693 FT CDS 202699..203217 FT /transl_table=11 FT /gene="SCO0481" FT /gene_synonym="SCF80.02" FT /product="putative secreted chitin binding protein" FT /note="SCF80.02, possible secreted chitin binding protein, FT len: 172 aa. This CDS has been previously sequenced but was FT unclassified: Streptomyces coelicolor TR:Q9Z9M5 (EMBL; FT AB017013) gene for ChiG, partial CDS (fragment) (172 aa), FT fasta scores opt: 1151 z-score: 1339.7 E():0 99.4% identity FT in 172 aa overlap. This CDS is similar to several e.g. FT Streptomyces reticuli TR:O87962 (EMBL; Y14315) chitin FT binding protein (Chb2) (201 aa), fasta scores opt: 193 FT z-score: 234.7 E(): 1e-05 37.3% identity in 201 aa overlap. FT Contains a possible N-terminal signal sequence." FT /db_xref="GOA:Q9RJF2" FT /db_xref="InterPro:IPR004302" FT /db_xref="UniProtKB/TrEMBL:Q9RJF2" FT /protein_id="CAB57190.1" FT /translation="MHARRKTAALIGAVLAPVVAVSLPASSASAHGYISDPPSRQAQCA FT AGTVSCGDITYEPQSVEGPKGLTSCSGGNSRFAELDDDSKGWQVTPVSKTTTFSWRLTA FT QHATSTWEYYVGGQRIALFDDGGAKPGSVVNHQVDFGGLTGQQKVLAVWNVADTSNAFY FT ACIDVNVGG" FT RBS 203329..203333 FT CDS 203342..204076 FT /transl_table=11 FT /gene="SCO0482" FT /gene_synonym="chiG" FT /gene_synonym="SCF34.01" FT /product="secreted chitinase" FT /note="SCF80.03, secreted chitinase, partial CDS, len:> 187 FT aa. Previously sequenced and characterised. Streptomyces FT coelicolor TR:Q9Z9M4 (EMBL; AB017013) chiG (fragment) (244 FT aa), fasta scores opt: 1238 z-score: 1463.2 E():0 98.9% FT identity in 187 aa overlap. Contains a possible N-terminal FT signal sequence and a Pfam match to entry PF00182 FT Glyco_hydro_19, Chitinases class I." FT /note="SCF34.01, chiG, chitinase, partial CDS, len: >90 aa; FT identical to the C-terminus of TR:Q9Z9M4 (EMBL:AB017013), FT chiG, Streptomyces coelicolor chitinase (fragment) (244 FT aa), fasta scores; opt: 638 z-score: 812.8 E(): 0, 100.0% FT identity in 90 aa overlap. Highly similar to SC5H1.29c FT (EMBL:AL049863), chiF, Streptomyces coelicolor chitinase FT (296 aa) (81.1% identity in 90 aa overlap). Contains Pfam FT match to entry PF00182 Glyco_hydro_19, Chitinases class I" FT /db_xref="GOA:Q8CK55" FT /db_xref="InterPro:IPR000726" FT /db_xref="PDB:2CJL" FT /db_xref="UniProtKB/TrEMBL:Q8CK55" FT /protein_id="CAD55444.1" FT /translation="MQHRKLALLAATGAAAALCTLTMAPSAVAEKSDTRTAAAEFVVSE FT AQFDQMFPSRNSFYTYSGLTAALSAYPGFSNTGSDTVKKQEAAAFLANVGHETGGLVYV FT VEQNTANYPHYCDASQPYGCPAGNDKYYGRGPVQLSWNFNYKAAGDALGIDLLNNPDLV FT QNDSAVAWKTGLWYWNTQTGPGTMTPHDAMVNGAGFGETIRSINGSLECDGGNPGQVQS FT RIDNYERFTQLLGVEPGGNLSC" FT misc_feature 203465..203875 FT /note="Pfam match to entry PF00182 Glyco_hydro_19, FT Chitinases class I, score 195.40, E-value 9.1e-55" FT misc_feature 203804..204073 FT /note="Pfam match to entry PF00182 Glyco_hydro_19, FT Chitinases class I, score 87.60, E-value 7.6e-24" FT misc_feature 203804..204330 FT /note="sequence corresponding to Streptomyces coelicolor FT gene for ChiG, partial cds (EMBL:AB017013) from 1449 to FT 1975" FT CDS complement(204073..204474) FT /transl_table=11 FT /gene="SCO0483" FT /gene_synonym="SCF34.02c" FT /product="putative secreted protein" FT /note="SCF34.02c, putative secreted protein, len: 133 aa; FT unknown function, possible CDS suggested by GC frameplot. FT Contains an Arg-rich region" FT /db_xref="UniProtKB/TrEMBL:Q9RK23" FT /protein_id="CAB53313.1" FT /translation="MDALLPFVLLAGGLAAVLGSFTWLASRVRRRGLAGGAMGAALASY FT EEAFRTTAYASHVEIRAQAERRSPLLSPDDWRWAPAAPDGTGAEAGRTASRGSSRSRRG FT RARWFRRRRGPLATGHSGGHEGAGGPDGS" FT CDS complement(204539..205705) FT /transl_table=11 FT /gene="SCO0484" FT /gene_synonym="SCF34.03c" FT /product="putative monooxygenase" FT /note="SCF34.03c, possible monooxygenase, len: 388 aa; FT similar to SW:TETX_BACFR (EMBL:M37699), TetX, Bacteroides FT fragilis tetracycline resistance protein from transposon FT Tn4351/Tn4400 (388 aa), fasta scores; opt: 582 z-score: FT 637.6 E(): 3.7e-28, 33.9% identity in 351 aa overlap. Also FT similar to monooxygenases e.g. TR:P96555 (EMBL:AB000564) FT Sphingomonas sp. salicylate hydroxylase (395 aa) (27.2% FT identity in 360 aa overlap). Similar to others from FT S.coelicolor e.g. TR:Q9Z4Y6 (EMBL:AL035707) S.coelicolor FT possible salicylate hydroxylase (420 aa) (32.9% identity in FT 340 aa overlap). Contains Pfam match to entry PF01360 FT Monooxygenase, Monooxygenase" FT /db_xref="GOA:Q9RK22" FT /db_xref="InterPro:IPR003042" FT /db_xref="UniProtKB/TrEMBL:Q9RK22" FT /protein_id="CAB53314.1" FT /translation="MNSPTPAAARISIIGAGPGGLTCARVLRRHGIAVTVYDRDPDAAS FT RDQGGSLDLHEEDGQLALREAGLLEEFFALARCESQEERRFDTAGRLLGRRLPDEGETA FT RPEIDRGQLRGLLLESLDAGTVRWGHGLESVSGPAEGPRTLTFTDGSTVETDLVIGADG FT AFSRVRAAVSDAVPRYTGVGFLEAWFDDMESAHPELSELVGRGSAHVADGQRGLFAQRN FT SGGHMRVYVMRRVALDWMTASGLRPDDTDGIRARLLAEYAGWSPRILRMITENDGPYVD FT RPLFALPVPHTWRPTPGVTLLGDAAHLMPPLGVGVNLAMLDGAELALALAASATVDDAV FT RTYEKTMLPRSAEIAGMLEGGAGFLLEEPDAEDLARLGAPGADGGPGE" FT misc_feature complement(204629..205246) FT /note="Pfam match to entry PF01360 Monooxygenase, FT Monooxygenase, score 59.40, E-value 7.7e-14" FT CDS 205854..206465 FT /transl_table=11 FT /gene="SCO0485" FT /gene_synonym="SCF34.04" FT /product="putative tetR-family transcriptional regulator" FT /note="SCF34.04, possible tetR-family transcriptional FT regulator, len: 203 aa; shows weak similarity to FT SW:TCMR_STRGA (EMBL:M80674), TcmR, Streptomyces glaucescens FT tetracenomycin C transcriptional repressor (226 aa), fasta FT scores; opt: 201 z-score: 254.2 E(): 8.4e-07, 32.2% FT identity in 152 aa overlap and to many putative FT transcriptional regulators. Contains Pfam match to entry FT PF00440 tetR, Bacterial regulatory proteins, tetR family. FT Contains probable helix-turn-helix motif at aa 38-59 (Score FT 1212, +3.31 SD)" FT /db_xref="GOA:Q9RK21" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9RK21" FT /protein_id="CAB53315.1" FT /translation="MPDSPTPGRRERKKAATRQAIADAALQLFLEHGFDRVSVRDVAER FT ADVSTTTLFAHFPSKESLVFDREQEVDAALAAAVRERPDGQGVVEALRAHALESWVPIV FT TDPRRARFTALVSDTPALREYSERMWMRHADTLSTVIAEELDREPDDSACAALARFVLE FT IPALTTGRHDPRATVETVFDLLLHGWRSQAGPRPPQADGR" FT misc_feature 205914..206045 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 45.10, E-value FT 8.7e-11" FT CDS complement(206447..207670) FT /transl_table=11 FT /gene="SCO0486" FT /gene_synonym="SCF34.05c" FT /product="putative monooxygenase" FT /note="SCF34.05c, possible monooxygenase, len: 407 aa; FT similar to TR:Q9ZI64 (EMBL:AF039534), NahW, Pseudomonas FT stutzeri salicylate hydroxylase (389 aa), fasta scores; FT opt: 328 z-score: 383.8 E(): 5.1e-14, 27.0% identity in 403 FT aa overlap and to the N-terminal half of some epoxidases FT e.g. SW:ABA2_LYCES (EMBL:Z83835) Lycopersicon esculentum FT zeaxanthin epoxidase precursor (669 aa) (26.8% identity in FT 336 aa overlap). Also similar to many putative FT oxidoreductases e.g. TR:O54177 (EMBL:AL021411) Streptomyces FT coelicolor possible oxidoreductase (397 aa) (56.1% identity FT in 403 aa overlap). Contains Pfam match to entry PF01360 FT Monooxygenase, Monooxygenase" FT /db_xref="GOA:Q9RK20" FT /db_xref="InterPro:IPR002938" FT /db_xref="UniProtKB/TrEMBL:Q9RK20" FT /protein_id="CAB53316.1" FT /translation="MVHTSRPARRVLISGASIAGPALAHWLDRYGFEVTVVEKAAAVRG FT GGYAIDVRGTAREAVDRMGLLPALTEAHVDSQRITFVDAAGETVGSLQPEQLTGGEAGV FT DLEVRRGDLADALYAPLRDRVEFLFEDSIATLDDTGDAVHVVFDSGLRRTFDLVVGADG FT LHSNTRRLVFGPEEPFHRYLGHVFAGFTLPNEFGLAHEAVIWNEPGRSAVLYAHEPAGR FT LHGFLTFTREAPPFDAFRDPRAQRDLVAARFPERVWHLPRLVEGMREADDLFFDIVSQI FT HLRTWSHGRVVLAGDAAHATSFISGQGSSVALVGAYVLAGELAAHADHTEAFAAYERRM FT RPFAERNQALATSGGSAVTPATRQELEARNALLRDPEAAARAMVTTSAREGRAAHSSLE FT LPDYRPSA" FT misc_feature complement(206615..207211) FT /note="Pfam match to entry PF01360 Monooxygenase, FT Monooxygenase, score 95.00, E-value 1.5e-24" FT CDS 207842..208348 FT /transl_table=11 FT /gene="SCO0487" FT /gene_synonym="SCF34.06" FT /product="putative MarR-family transcriptional regulator" FT /note="SCF34.06, possible MarR-family transcriptional FT regulator, len: 168 aa; shows weak similarity to TR:Q53002 FT (EMBL:U51475), MucS, Rhizobium meliloti exopolysaccharide FT synthesis regulatory protein (190 aa), fasta scores; opt: FT 126 z-score: 160.1 E(): 0.15, 24.8% identity in 145 aa FT overlap and to hypothetical transcriptional regulators. FT Contains Pfam match to entry PF01047 MarR, MarR family" FT /db_xref="GOA:Q9RK19" FT /db_xref="InterPro:IPR000835" FT /db_xref="UniProtKB/TrEMBL:Q9RK19" FT /protein_id="CAB53317.1" FT /translation="MTPEAAEPAGPDDPHDDLLTVLPRLTQLSAAFNKGRLTERAAEAA FT GLALDRPAMGVLVTLRAADQPLRIGEIADRMQVVGPHVTRQVQALEKRGLVRRVADPHD FT RRASLIEPTGDGLDAANRYMTSLLGWFAEALADWPPQDREDLTRLLTRLADDVTARLAR FT LDAED" FT misc_feature 207986..208300 FT /note="Pfam match to entry PF01047 MarR, MarR family, score FT 64.20, E-value 2.8e-15" FT CDS 208394..211810 FT /transl_table=11 FT /gene="SCO0488" FT /gene_synonym="SCF34.07" FT /product="putative hydrolase" FT /note="SCF34.07, putative hydrolase, len: 1138 aa; unknown FT function, probable CDS suggested by GC frameplot, FT positional base preference and amino acid composition. FT Similar to TR:Q9S3L0 (EMBL:AJ238748) alfa-L-ramnisidase FT from Clostridium stercorarium (874 aa) fasta scores; opt: FT 554, Z-score: 585.8, E(): 5.4e-25, 27.513% identity FT (30.672% ungapped) in 796 aa overlap." FT /db_xref="GOA:Q9RK18" FT /db_xref="InterPro:IPR006311" FT /db_xref="UniProtKB/TrEMBL:Q9RK18" FT /protein_id="CAB53318.1" FT /translation="MHRIVKRAVETFQAQRRTHMSEETTEGSTEGSTGESTGNGTEGWN FT RRVFLRGTVTTAGVAGVTALTGRGAVAAAGSGTGDGPAKTGTTGTGLRVVRTGVEYTEN FT LLGTDVERPRLSWELAAPGHGARQTAYHVRVTRGSGGRGPRTRTVWDSGKVASDRSVGI FT PYGGPALLPRTRYHWQVRVWDAAGRRSRWSETRWWETSLPADGWRARWIGAEEPPSPPS FT LEGASWIWSPGATASDAPEGERRFRATLTLPAGSVVKRAVVSATADDDFTLYVGGQQVL FT HAPLQTDGWRTGRTADVTEQARSADGAILVAALATNRPGASVNPGGFLARLLVETEDGR FT TRELRTGDGWRTSGTAQEGWERPGFDDGDWEPAAVLAPYGQGPWGGNVTVTGPEAPAPL FT LRRDFTVHGRVARARLHISGLAYYEAEINGRRVGDQVLDPGFTDYDETVLYAVHDVTEL FT LRSGENAIGVAVGRGFYGMTTPNVWNWHRAPWHGEPRLLAQLEIDHPDGTRTTVATDGE FT WRITEGPTLSNSLYAGETYDARRAPEGWSRAGFDDSGWRSAGVREAPGGTLRAQPHDPI FT GIVDTVRPKAVGELRDGVYVVDMGRTMAGWTRLTVRGAAEGTVVRLVHGEKLEDDGSVH FT AETGHVPGRFQTDEYVCAGRDEEVWEPSFSYKGFRYVEVHGLHARPAPEDVLGRLVHSR FT VDEVSSFSCSEPFYEWLDRAMRRTVLNNLHGIPTDTPMYEKNGWTGDAQLGTPVMTYAF FT GMQRFLSKWLGDLADSQNDDGQLPVIVPSGGWGYGDLGPSPEWTTVYPFVVRELYRVYG FT DERAAREHWETLTRYLDWELGRLRDGLAVTALGDYLAPGYGGNPPEDTRLTATAYLYRA FT LLHTAELGEALTGLPGDNDVPGRYRAAAEELRKAFNEAFLGPDGHYRTAKDPDYRQTSN FT AIPLAFGLVPPGARATVLESLVADIEERGNHLNTGALGTSVLLRVLCAHGRPDVAHAVA FT TRRTYPGWGYWHDNGADTMWEMWPLDSRSRDHYFQGTVAQWLYENVAGLRPGDAGWRTF FT TVRPDARTGVEWARTSIRTVRGEAAVAWSAVDGRLRLTVRVPVGSRAEVHVPVSEGGRA FT TVPRGAEFVRSVPGFDILRAGHGSWEFTGDA" FT CDS complement(211823..212035) FT /transl_table=11 FT /gene="SCO0489" FT /gene_synonym="SCF34.08c" FT /product="conserved hypothetical protein" FT /note="SCF34.08c, conserved hypothetical protein, len: 70 FT aa; unknown function, similar to hypothetical proteins from FT several bacteria e.g. SW:MBTH_MYCTU (EMBL:Z95208), MbtH, FT Mycobacterium tuberculosis hypothetical protein (71 aa), FT fasta scores; opt: 329 z-score: 486.3 E(): 9.9e-20, 70.3% FT identity in 64 aa overlap. Also similar to TR:Q9Z388 FT (EMBL:AL035654) Streptomyces coelicolor small conserved FT hypothetical protein (71 aa) (74.2% identity in 62 aa FT overlap)" FT /db_xref="InterPro:IPR005153" FT /db_xref="UniProtKB/TrEMBL:Q9RK17" FT /protein_id="CAB53319.1" FT /translation="MSTNPFDDADGRFLVLVNDEGQHSLWPAFAAVPGGWTTVFEENTR FT DACLAYVEANWTDLRPRSLARTADA" FT CDS 212124..213215 FT /transl_table=11 FT /gene="SCO0490" FT /gene_synonym="SCF34.09" FT /product="putative esterase" FT /note="SCF34.09, possible esterase, len: 363 aa; similar to FT enterochelin esterases e.g. SW:FES_ECOLI (EMBL:J04216), FT Fes, Escherichia coli enterochelin esterase (374 aa), fasta FT scores; opt: 422 z-score: 474.2 E(): 4.7e-19, 32.5% FT identity in 332 aa overlap" FT /db_xref="InterPro:IPR000801" FT /db_xref="UniProtKB/TrEMBL:Q9RK16" FT /protein_id="CAB53320.1" FT /translation="MRWAGADAFAAFGLTAVPGTDAFWDGLTTPRSIPDGDGWTTLFLR FT RGPRAASIVFESWSAPVPLRRWRDTDCWYAEVRMPPRLRVTYRFVVGEEAYADPYNPAG FT AGGERSVAATPDAPAQPHWPLVGAGDVLPLPRVRLRWTSERLGGRRTVRVHPVGGGGPV FT VLLLDGDDWLYLHPATSAFDSAVASGEMPPVTLVFLPAGDRGAEFGCRPALWEAVRDEL FT LPLVAGSGVRADPGRTVVAGQSLGGLSALYAALEFPELVSRVACQSASLWWTPGAADLP FT DPLGGPVGGAIAARLRARPDLSGLRIAFDVGEHERRMLPHCALVESLTEQAGATVRVSR FT SASGHDRAGWRHALLRDVAWALA" FT CDS complement(213302..214924) FT /transl_table=11 FT /gene="SCO0491" FT /gene_synonym="SCF34.10c" FT /product="putative ABC transporter transmembrane protein" FT /note="SCF34.10c, probable ABC-transporter transmembrane FT protein, len: 540 aa; similar to transporters e.g. FT SW:PRTD_ERWCH (EMBL:M60395), PrtD, Erwinia chrysanthemi FT proteases secretion ATP-binding protein (575 aa), fasta FT scores; opt: 433 z-score: 468.5 E(): 9.7e-19, 29.1% FT identity in 413 aa overlap. Similar to TR:O87312 FT (EMBL:AF027770), FxtA, Mycobacterium smegmatis hypothetical FT protein at exochelin locus (574 aa) (39.7% identity in 524 FT aa overlap). Similar to others from S.coelicolor e.g. to FT the N-terminal half of TR:Q9ZBY5 (EMBL:AL034355), CydCD, FT Streptomyces coelicolor probable ABC transporter (1172 aa) FT (29.6% identity in 550 aa overlap). Contains hydrophobic, FT possible membrane-spanning regions. Contains Pfam match to FT entry PF00005 ABC_tran, ABC transporter and PS00211 ABC FT transporters family signature" FT /db_xref="GOA:Q9RK15" FT /db_xref="InterPro:IPR001140" FT /db_xref="UniProtKB/TrEMBL:Q9RK15" FT /protein_id="CAB53321.1" FT /translation="MAWGTLLMGLYQAGETAFPIALGLIVEHTMRDRSPQALGVSVAAL FT AVIITTVSLSWRFGMRILQKANTTEAHRWRVRVAGRGLQPVARDVDLKSGEVLTIATED FT ADQTADIIEVVPLLISSLVAVVIAAVALGLADVRLGLLVIVGTVAILSVLSVMSRRIGS FT STREQQARVARAGAKVADLIIGLRPLHGFGGNHAAFRSYREISTEAKRQSVTVARVSGV FT YAGTALALNAVLAAAVTLTAGWLAFRGRIGIGELVMAVGLAQFVMEPLKLFSEMPKYVM FT IARASAERMALVLAAPPVTTPGTERPAAGGDLEVDGVRHGALRKVRFRVRAGEFVAVAA FT YQPLAAADLAAVLALNVPPDTYEGTVRVGGRDLAELAVEEVREHLLVNPYDGEIFAGTL FT RSNIDPSGTSRTVPEAVEASMLTDVVALHREGLDYAVRDRGANLSGGQRQRLSLARALA FT ADSEVLVLRDPTTAVDAVTEQLIARGVAKLRRDRTTLVITSSPALLDAADRVLVLDEGV FT ITAEDTHRNLLATDEAYCVAVTR" FT misc_feature complement(213377..213880) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 71.90, E-value 1.4e-17" FT misc_feature complement(213554..213598) FT /note="PS00211 ABC transporters family signature" FT CDS complement(214989..225920) FT /transl_table=11 FT /gene="SCO0492" FT /gene_synonym="SCF34.11c" FT /product="putative peptide synthetase" FT /note="SCF34.11c, probable peptide synthetase, len: 3643 FT aa; similar to parts of many antibiotic peptide synthetases FT e.g. the C-terminal half of TR:Q9Z4X6 (EMBL:AL035640) FT Streptomyces coelicolor CDA peptide synthetase I (7463 aa), FT fasta scores; opt: 1948 z-score: 1929.3 E(): 0, 33.7% FT identity in 3723 aa overlap. Also similar to parts of FT putative peptide synthetases from the exochelin FT biosynthesis locus of Mycobacterium smegmatis TR:O87314 FT (EMBL:AF027770), FxbC, putative peptide synthetase (4976 FT aa) (42.3% identity in 3756 aa overlap). Contains 3 Pfam FT matches to entry PF00550 pp-binding, Phosphopantetheine FT attachment site, 3 Pfam matches to entry PF00501 FT AMP-binding, AMP-binding enzyme, 4 Pfam matches to entry FT PF00668 DUF4, Domain of unknown function, 2 PS00455 FT Putative AMP-binding domain signatures, 2 PS00012 FT Phosphopantetheine attachment sites and 1 PS00017 FT ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9RK14" FT /db_xref="HSSP:1AMU" FT /db_xref="InterPro:IPR010071" FT /db_xref="UniProtKB/TrEMBL:Q9RK14" FT /protein_id="CAB53322.1" FT /translation="MMEPTASLVRLSPAQLAGLRRRTGDFSDQVITEACAVALAYWAEG FT RGPAGLDLAPGTLFTDVLGWADSGGTAPTGWGADAGTVTVPGGVVPHEAQLALDDLADF FT PDRPLGTVGPCGPAERLELLAGWNDTDADRARPGLVEMFREQARARPDAVAVVDERRTL FT TYRQVEKLSAQLAHQLLARGLAVEDVVGISLERSAEMVIGLLAVLRAGGAFVPLDPHWP FT AERRAVVIEDAGVVVQLDASGEPAPGEPEAVAVDLGDWRFGDRPTEDTGVTVPGDALAY FT VIFTSGSTGRPKGAMIRHEAISERLLWQIHEILGFGHDDASLFKAPLSFDISINEIFLP FT LVSGGRLVVLRPGGERDPHHLLSVIDEQRVTFTYLVSSMLDVLLEMAGDSGRLDSLRHV FT WCGGEVLTPELYERFRTRLDIPLYHGYGPAETTIGVSHVVYRGAAERLSTSIGRANPNT FT RLYVLDDELRPVPVGVGGELYAGGLLLGRGYVNAPGLTASRFVANPFADDGSRLYRTGD FT LARFAPDGSLDFLGRADNQVKIRGMRLEIEDVEVGLAEHPRVRHTCVVARKNTAGGTYL FT VGYVIPAAGHEDLRADEVKAWAGEHMVEYMVPTHVVVMTEFPLTANGKLDRNALPEPVI FT PAGSSAPPTTDEERTVCAAVAALLQLDRVGVDQDFFQLGGDSILAISLLGRLRDAGLYV FT TARQIFTHSTVGALAAVASREDTTVVDHRDVPTGSVVGSPVVQWLGETTDAIDGFVQSV FT VLNTPADLTADALDLILAAVVRRHPMLRARLVRGERWGFDIPEAEAVPAVALWRESDQP FT LDACLALATGELDPVGGAMLRAVWRREARQLALVVHHVVIDGVSWRVLMDDLATAWRQF FT TSGTAVELPSGGTSFRRWTQLLERAAFDADSAYYRRALPGPDEPLGGRPLRADDTVARE FT RIRTVSIGATATAALLGDTPAKFHTGINDVLVTALAVALARRRHDLGQTQTFAHIELEG FT HGREAAFVAPSAGFEPELSRTVGWFTTLFPVTVDPGTAPDPTAPAYLSAALKAVKEDLA FT RVPDHGVSYGALRHLARVAFDAPAPQVLFNYLGRFDAGSSGDWQLASVNGQLGEQRDPR FT MRLPRALEFNAIAEPDATGAYTLVTAISWPDGMFTDTDITTLGAYYVEALTGLAALENG FT GHSPSDFHPLPLTQADVDALDGPALRDILPLTPLQEGLYFHSVYDGDATGSYVEQQLLT FT LEGEVDPGRLAAAATRLLTLHPNLAARFVPLADGRVVSVLESGREAPFTVLDRPGITDD FT EIRAHAEHDRRAGFDLATGPPMRYTLIRSGPRRHVLVQTVHHIVADGWSVPPMLRTLLA FT EYRAPGSGHALGGFPEHVRRLAARDGAASDRVWDEQLADLPGPSLIAEGHPPSAHFADT FT ATTADTDVDAAARAAGVPLSVAVHGAWALTLGGILHRDDVVFGSTVSGRDADVPGIGDM FT VGLFINTIPLRARWADTTTARELLTAVRAHQAAVLPHQHVSLARIARRAGAGALFDTLV FT VFDVATDVAGLRRPGDPLAVTGIVNEGAPHYPLTLVVERTPDGRPRFNLIHDAELLREP FT EVREILRTFTRTLTHLLTRPEAPVGGLASEGTGRVEPVPPATLGELFDAAARRGPAAAA FT VTQCALDGATRSLTYGELSLAKDELAAVLRAAGVGPGKRVAVAVPRSVEQVVALVAVVG FT AGGAYVPLDLAYPDERLEYVLADSAPQVVLVTPEQRDRFARLLDRANVPARLLVLGEEP FT PPTAAEPGPAARWHDPAYVIYTSGSTGRPKGVVVPHSSVVTLLANTRPVMNFGPDDVWV FT QFHSFSFDFAVWELWGALTHGGELLVPDYGLTRSPVDFHRLVRERGVTVLNQTPSAFHR FT FAEADRHAGEPLPALRRIIFGGEGLDLARLRDWVARHGTESPELVNMYGITETTVHVTH FT RVLTAADFAPGDRAASPIGGPVPGLVTHLLDDRLRPVPPGRVGAIYVAGDQVSLGYLGR FT PGLTAGRFVANPFTADGSRMYHTGDLARRTLDGQLEFAGRADDQVQLKGFRIEPGEVES FT AIRDLDGVVDAAVTVADTDDHLVAHVVGRVPADLTGLLSAKLPAHMVPGRVLPVDALPL FT TVNGKLDRRALAERATRTPSAEPAPHGGNDSVLATLVGLFAETLPGSAPDADTDFFAAG FT GDSIVAITVINRARAAGLPVAPRDVFLLRTPRALAEHLATRTPPPEASPAPTGHQDGPL FT PPTPIMLRQRELGGSLARFAQARTLAAPEGTGFADAERAARAVVGAHPALRLRLRVEHG FT VWSLSTEPAREVAVTRGSGTDVTQTADEAAGRLDPENGDIVAFTWLETSRTLVVAVHHL FT AVDAVSWLILLDDLAAAMRGAVPAPPTTPYAEYARALTHRAAQQTDGLDHWISTLGAPA FT PLPAAGKRRETTVVLAPGVSDRVTRTAPAALGLGLTELLCGALRTALTRVQRTPTDLAI FT DLERHGRVPALDHHDYTRTVGWFTAIAPVRLTAHTDPVAAAREVTARRPDEHAHVAYGG FT LRYLNPQTAPLLGTARPQALFNYLGRGAESDAPRLTGADAGSPYAVEVNAWTDAATGGL FT HAAFTLAEGVPDEITEHWHRALERIADAAATAERTAPVSPLQRGLYFQAQLTGPAGHYV FT AQSYFTFERRLEPDALSRAAACVLARHPATGAGFTTDEDGNPVQVLAAGRRIDVHTVEA FT ATDAEVDALRLGDRERGFDPAEPPLIRLTVVRLPDDRDGLLLSYHLLLWDGWSREIVLR FT DLFDAYRAVLAGEPLDPGPAAPGFEDHARALAARDPAPSERFWARHLAGLSGPTLLAGP FT APALPDDLPRALAHTLTAERSDALRAAARTYGVTLNSVLTGAFGLLLGARTGRADAVFG FT VTVSGREGEGLADIVGVLLNTVPMWTRARPHDTVRAYLTAVQEARVDAMEHEHLGLGEI FT QRASGHDTLFDNLFVLQNFLDLDAFAEMNARHGITSVRADDSTHYPFTWVVTPGDRLTV FT KLEYRDHDTGHARALLDDYLRVLDDLAGRSGAAESRAPIGALPGLAPAPEPAPRTGIGT FT DTVVDRFDRAADREPDRTALVAHGSTMTFAHLRDRSRAVAGVLARRGIGPGATVGLALP FT RSLDSIVALFAVLRTGAAYVPLELDHPDERIAAVVADARPDAVLTVSAVTPRLTGGPDL FT IELDRPLPDAEPCVTFAPDDPDRLRHPAYTIYTSGSTGRPKGVVTEYAGLTNMLVNHRR FT RIFEPVLARHGHRTFRVAHTVSFAFDMSWEELLWLADGHEVHVCDEELRRDAPRLVAYC FT LEHGIDVVNVTPTYAQQLLAEGLLDDPARRPALVLLGGEAVTPALWTRLAATEGTVGYN FT LYGPTEYTINTLGVGTFECPDPVVGVAIDNTDVYVLDPWLRPLPDGVPGELYVAGVGIA FT RGYLGQPAQTAHRFVACPFGAPGERMYRTGDLVVRRPDGNLMYLGRTDQQVKIRGHRVE FT PGEVEAAFAAHPAVRFVAAVAQPDPQVDGAHRLAAYLVLDGADLAEVAAQVGAALPDFL FT RPTHYAQVDRIPLTVNGKADTKALPEARPLGALTTAGERAPRTETETTVCELFAEALDL FT DDDEVSAVSDFVALGGHSMLAVRLTGLLRREYGPVITIRDLFTLRTPEAIARHLDDHS" FT misc_feature complement(215004..215204) FT /note="Pfam match to entry PF00550 pp-binding, FT Phosphopantetheine attachment site, score 58.90, E-value FT 1.2e-14" FT misc_feature complement(215082..215129) FT /note="PS00012 Phosphopantetheine attachment site" FT misc_feature complement(215460..216677) FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 360.70, E-value 1.6e-104" FT misc_feature complement(216951..218081) FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 227.30, E-value 2.2e-64" FT misc_feature complement(218154..219251) FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 4.30, E-value 9.8e-10" FT misc_feature complement(219300..219491) FT /note="Pfam match to entry PF00550 pp-binding, FT Phosphopantetheine attachment site, score 49.80, E-value FT 3.8e-12" FT misc_feature complement(219375..219422) FT /note="PS00012 Phosphopantetheine attachment site" FT misc_feature complement(219729..220967) FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 473.00, E-value 2.4e-138" FT misc_feature complement(220563..220598) FT /note="PS00455 Putative AMP-binding domain signature" FT misc_feature complement(221241..222350) FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 178.50, E-value 1.1e-49" FT misc_feature complement(222552..223745) FT /note="Pfam match to entry PF00668 DUF4, Domain of unknown FT function, score 89.10, E-value 8.7e-23" FT misc_feature complement(223785..223976) FT /note="Pfam match to entry PF00550 pp-binding, FT Phosphopantetheine attachment site, score 62.90, E-value FT 9e-16" FT misc_feature complement(224229..225431) FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 451.90, E-value 5.6e-132" FT misc_feature complement(225042..225077) FT /note="PS00455 Putative AMP-binding domain signature" FT CDS complement(225978..227783) FT /transl_table=11 FT /gene="SCO0493" FT /gene_synonym="SCF34.12c" FT /product="putative ABC-transporter transmembrane protein" FT /note="SCF34.12c, probable ABC-transporter transmembrane FT protein, len: 601 aa; similar to the C-terminal half of FT TR:O85018 (EMBL:AF034152), ExiT, Mycobacterium smegmatis FT ABC-transporter associated with ferric exochelin FT biosynthetic and uptake (possibly involved in exochelin FT secretion) (1122 aa), fasta scores; opt: 1778 z-score: FT 1789.6 E(): 0, 50.4% identity in 585 aa overlap, to FT TR:Q54204 (EMBL:X89010), StrW, Streptomyces glaucescens FT putative ABC-transporter from the hydroxystreptomycin FT production locus (591 aa) (33.1% identity in 577 aa FT overlap) and to many other ABC-transporters. Similar to FT many others from S.coelicolor e.g. to the C-terminal half FT of TR:Q9ZBY5 (EMBL:AL034355) CydCD, S.coelicolor probable FT ABC transporter (1172 aa) (30.3% identity in 574 aa FT overlap). Contains hydrophobic, possible membrane-spanning FT regions. Contains Pfam matches to entry PF00005 ABC_tran, FT ABC transporter and to entry PF00664 ABC_membrane, ABC FT transporter transmembrane region. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9RK13" FT /db_xref="HSSP:1PF4" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9RK13" FT /protein_id="CAB53323.1" FT /translation="MSATDTRVATAPAVLRTATGGESGRWVAAHCREVPWLTAATVLTT FT VAGAALQVLPVLLLGRVVDAVAGGESQDVLVTIGILMVAAALLGAVATAVSTCLIGRLG FT ADLLARLREGAVRAVLAMPSARVEQVGRGDVLSRVGDDVAVISKGIRTAVPTVFSAGVL FT VAIATAGMFGLDWRLGLAGAGALPAYALALRWYLPRSAPLYRKQRVAQADRAQALISGL FT NGIDTVRAYRLEGAFRERVTRESWRVRELGIEVFRFFGRFVGRENRAEFIGLTLIIVVG FT YALLEADAATLGEVSAAPLLFHRLFTPLGAIMFTFDEAQKSGASLTRLVGVLGEDAADR FT LVGDASVGTAAAGAYPVTVRGLTFTYPGADEPVLRDVDLTIPAGGSLALVGATGAGKST FT LAALVAGIGTPQAGSVRVGPADLAELDEAGARALVSILTQETHVFSGPLADDLRLAAPE FT ATDAELLDALRTVGAGQWVDALPDGLDTPVGEGGERLDVTKVAQIALARLVLGRAPVVV FT LDESTAEAGSEGAAELERAVLAACAGRTTLFVAHRLTQAMAADRIAVLDAGRVVEEGTH FT AELVALGGRYARLWRAWREGGRAGC" FT misc_feature complement(226080..226634) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 89.20, E-value 8.1e-23" FT misc_feature complement(226590..226613) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(226857..227675) FT /note="Pfam match to entry PF00664 ABC_membrane, ABC FT transporter transmembrane region., score 93.10, E-value FT 5.7e-24" FT CDS complement(227786..228838) FT /transl_table=11 FT /gene="SCO0494" FT /gene_synonym="SCF34.13c" FT /product="putative iron-siderophore binding lipoprotein" FT /note="SCF34.13c, probable iron-siderophore binding FT lipoprotein, len: 350 aa; similar to TR:Q46023 FT (EMBL:U02617) Corynebacterium diphtheriae FT DtxR/iron-regulated lipoprotein precursor (355 aa), fasta FT scores; opt: 479 z-score: 518.8 E(): 1.5e-21, 34.4% FT identity in 358 aa overlap and SW:FATB_VIBAN (EMBL:J03529), FT FatB, Vibrio anguillarum plasmid pJM1 ferric FT anguibactin-binding protein precursor (322 aa) (26.2% FT identity in 305 aa overlap). Also similar to other FT iron-siderophore binding proteins. Contains an FT appropriately positioned PS00013 Prokaryotic membrane FT lipoprotein lipid attachment site and a possible N-terminal FT signal sequence. Contains Pfam match to entry PF01497 FT Peripla_BP_2. Contains a probable coiled-coil from 189 to FT 219 (31 residues) (Max score: 1.558, probability 0.98)" FT /db_xref="GOA:Q9RK12" FT /db_xref="InterPro:IPR002491" FT /db_xref="UniProtKB/TrEMBL:Q9RK12" FT /protein_id="CAB53324.1" FT /translation="MLLRTTRTKPWRRLAAALSAAALGVGLLAGCGSDSDDPADEAGGG FT TPAAAGAFPVTVEHAFGTTKIDKAPERVVSVGYTDDQTVLAFGIKPVGMVDQYPNPAGQ FT SPDINTQWPWVKDKWGDTKPEVVMKNGDTGPNFEKIAALRPDLIVAVYSEIDQAAYDKL FT SKIAPTVGRTKGEKEPFSAPWQDNALHIAKALGKAEEGEKMVADIQGKLDAAKQAHPEF FT ADKTAVVLSWYKDSVAPFTSTDVRGRLVTGIGFKYETEIDKVAGGDFYTTLSPERVDLV FT DVDRVFVINDKADQDALKKFELFTNLDAVKNGKVSYLLDSEGPAVGAAISQGTLLSMPY FT AVDELVKSAG" FT misc_feature complement(227870..228631) FT /note="Pfam match to entry PF01497 Peripla_BP_2, , score FT 96.40, E-value 5.5e-25" FT misc_feature complement(228746..228778) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(228889..229752) FT /transl_table=11 FT /gene="SCO0495" FT /gene_synonym="SCF34.14c" FT /product="putative iron-siderophore ABC-transporter FT ATP-binding protein" FT /note="SCF34.14c, probable iron-siderophore ABC-transporter FT ATP-binding protein, len: 287 aa; similar to SW:FEPC_ECOLI FT (EMBL:X57471), FepC, Escherichia coli ferric enterobactin FT transport ATP-binding protein (271 aa), fasta scores; opt: FT 946 z-score: 1003.1 E(): 0, 52.3% identity in 262 aa FT overlap and to many other iron-siderophore ATP-binding FT proteins. Similar to many others from S. coelicolor e.g. FT SCI51.25c (EMBL:AL109848) S.coelicolor probable FT iron-siderophore uptake system ATP-binding component (301 FT aa) (58.9% identity in 258 aa overlap). Contains Pfam match FT to entry PF00005 ABC_tran, ABC transporter, PS00211 ABC FT transporters family signature and PS00017 ATP/GTP-binding FT site motif A (P-loop)" FT /db_xref="GOA:Q9RK11" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9RK11" FT /protein_id="CAB53325.1" FT /translation="MVVQSITGTETEVDGASRLAARGVTVGYGTRSVIDGLDVAIPPGV FT ITTIIGPNGCGKSTLLRTLSRLLRPTGGTVVLDGEDIAALRTRDVAKKLGLLPQAPVAP FT EGLTVSDLVARGRHPHQSWLRQWSSDDADVVRQALAMTGVSDLADRPVDSLSGGQRQRV FT WISMTLAQGTDLLLLDEPTTYLDLAHAVDVLDLVDDLHESGRTVVMVLHDLNLAARYSD FT NLVVMREGAILAQGHPRDVITAGLLHEAFGLRAKVIDDPVGDRPLIVPIGRTHVELDRS FT APELLK" FT misc_feature complement(229063..229623) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 196.10, E-value 5.3e-55" FT misc_feature complement(229246..229290) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(229579..229602) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(229791..230897) FT /transl_table=11 FT /gene="SCO0496" FT /gene_synonym="SCF34.15c" FT /product="putative iron-siderophore permease transmembrane FT protein" FT /note="SCF34.15c, probable iron-siderophore permease FT transmembrane protein, len: 368 aa; similar to FT SW:FEPG_ECOLI (EMBL:X57471), FepG, Escherichia coli ferric FT enterobactin transport protein (330 aa), fasta scores; opt: FT 741 z-score: 794.3 E(): 0, 38.7% identity in 326 aa overlap FT and to many other iron-siderophore permeases. Similar to FT others from S. coelicolor e.g. SCI51.26c (EMBL:AL109848) S. FT coelicolor probable iron-siderophore uptake system FT transmembrane component (375 aa) (45.9% identity in 333 aa FT overlap). Contains hydrophobic, possible membrane-spanning FT regions. Contains Pfam match to entry PF01032 FecCD_family, FT FecCD transport family" FT /db_xref="GOA:Q9RK10" FT /db_xref="HSSP:1L7V" FT /db_xref="InterPro:IPR000522" FT /db_xref="UniProtKB/TrEMBL:Q9RK10" FT /protein_id="CAB53326.1" FT /translation="MNGTDMRADGADAAVDVKADVRTSVAPGVRFGGLSFVWRPWVAGV FT TLLLAVAGFLVFCLSIGVGDFPIALPRVVATVFGGGEQVDRFVIMDLRMPRALAGLVVG FT VALGVSGALTQSIARNPLASPDVLGITSGAGAVAVFLVTVSGGAATAVADSVGLSAAAL FT AGGLGTGLLVYFMAWRRGIDGFRLILIGISVNAVMQAITTWLLVTADIRDVARAQAWLV FT GSLDNRSWGEVHVALWCTLVLLVVVASVAFQFKPLHFGDDVAAGLGVRYGTVRAVLLLC FT AVLLAGVAVSAAGPVPFVALVAPQVAMRLARCPTPPLVASGLVGALLLTGSDLLARTAL FT PVSLPVGVVTAAIGGPFLVYLLVRANRR" FT misc_feature complement(229806..230708) FT /note="Pfam match to entry PF01032 FecCD_family, FecCD FT transport family, score 305.20, E-value 8.1e-88" FT CDS complement(230894..231970) FT /transl_table=11 FT /gene="SCO0497" FT /gene_synonym="SCF34.16c" FT /product="putative iron-siderophore permease transmembrane FT protein" FT /note="SCF34.16c, probable iron-siderophore permease FT transmembrane protein, len: 358 aa; similar to FT SW:FEPD_ECOLI (EMBL:X57471), FepD, Escherichia coli ferric FT enterobactin transport protein (334 aa), fasta scores; opt: FT 796 z-score: 833.5 E(): 0, 43.9% identity in 330 aa overlap FT and to many other iron-siderophore permeases. Similar to FT others from S.coelicolor e.g. SCI51.27c (EMBL:AL109848) FT S.coelicolor probable iron-siderophore uptake system FT transmembrane component (348 aa) (46.8% identity in 344 aa FT overlap). Contains hydrophobic, possible membrane-spanning FT regions. Contains Pfam match to entry PF01032 FecCD_family, FT FecCD transport family" FT /db_xref="GOA:Q9RK09" FT /db_xref="InterPro:IPR000522" FT /db_xref="UniProtKB/TrEMBL:Q9RK09" FT /protein_id="CAB53327.1" FT /translation="MYGAMTTTEVERPAPTPRGPTEARRRRVAGLGLLAALLLVAAAAS FT LAVGARALSPAEVWHGLFAAPESDQRLTEIRLIVQTVRVPRTVLAVVAGIALGVAGALI FT QGYTRNPIADTGLLGVNSGASFAVVSGIAAFGFTSPFQYVWFGFAGAAVAGVVVFGLSS FT IGRGAGNPLTLALAGQGVTVFLAAMTTAVALTDKASLNALRFWNAGSLTGVGFDVIGPV FT SAFIAAGLLLALTTLPSVNLLNLGDDVARGLGVNIALTRTVGIVAITLLAGAATAACGP FT IAFLGLMVAHVARYLTGPDYRWLVPYAGLLGAVVLLVCDIVGRLVVRPGELDAGVVVSL FT LGAPFFAVLVWRGKFKSA" FT misc_feature complement(230915..231826) FT /note="Pfam match to entry PF01032 FecCD_family, FecCD FT transport family, score 302.30, E-value 5.8e-87" FT CDS complement(231970..233325) FT /transl_table=11 FT /gene="SCO0498" FT /gene_synonym="SCF34.17c" FT /product="putative peptide monooxygenase" FT /note="SCF34.17c, probable peptide monooxygenase, len: 451 FT aa; similar to monooxygenases/hydroxylases associated with FT peptide siderophore biosynthesis e.g. SW:PVDA_BURCE FT (EMBL:AF013993), PvdA, Burkholderia cepacia L-ornithine FT 5-monooxygenase (444 aa), fasta scores; opt: 982 z-score: FT 1149.4 E(): 0, 43.5% identity in 405 aa overlap and FT SW:IUCD_ECOLI (EMBL:M18968), IucD, Escherichia coli FT L-lysine 6-monooxygenase (425 aa) (31.3% identity in 425 aa FT overlap). Also similar to others from S.coelicolor e.g. FT TR:Q9ZBH9 (EMBL:AL035206) S.coelicolor probable FT oxidoreductase, partial CDS (353 aa) (38.1% identity in 349 FT aa overlap)" FT /db_xref="GOA:Q9RK08" FT /db_xref="InterPro:IPR013027" FT /db_xref="UniProtKB/TrEMBL:Q9RK08" FT /protein_id="CAB53328.1" FT /translation="MSQVLPADSTLVHDLIGIGFGPSNVAMAIAIREHNAQAGGQEELD FT ARFFEQQPRFGWHRGMLIDDATMQVSFLKDLVTLRNPASRYSFLCYLQSRGRLIDFINH FT KNLFPLRVEFHDYFEWAAAKVDDMVSYGHEVVGVAPVVRDGVVDHLEVTVRSGEGLEVH FT RARNLVVGTGLRPLVPEGVERGDRVWHNSELLSRVDTLEGTSPSRFVVVGAGQSAAENV FT AYLHRRFPSAEICAVFARYGYSPADDSAFANRIFDPAAVDDYFTAPDGVKQRLMDYHGN FT TNYSVVDIDLIDDLYRQMYREKVLGTERLRFLNVSRLSDVKETPDRVRATVTSLVTGEE FT SHLDADVVVLATGYGPADPLGLLGEVADRCLRDDEGRVRVERDYRVTTDPALRCGIYLQ FT GGTEHTHGITSSLLSNTAVRVGEILESLLDRGLESASDEVRTVADGTGTGAR" FT misc_feature 233501..233989 FT /note="Pfam match to entry PF00551 formyl_transf, Formyl FT transferase, score 111.20, E-value 6.8e-31" FT CDS 233501..234448 FT /transl_table=11 FT /gene="SCO0499" FT /gene_synonym="SCF34.18" FT /product="putative formyltransferase" FT /note="SCF34.18, possible formyltransferase, len: 315 aa; FT similar to TR:Q50378 (EMBL:U10425), FxbA, Mycobacterium FT smegmatis putative formyltransferase required for exochelin FT biosynthesis (360 aa), fasta scores; opt: 942 z-score: FT 1102.4 E(): 0, 49.5% identity in 309 aa overlap. Also FT similar to many methionyl-tRNA formyltransferases e.g. FT SW:FMT_PSEAE (EMBL:AF073952), Fmt, Pseudomonas aeruginosa FT methionyl-tRNA formyltransferase (314 aa) (30.3% identity FT in 307 aa overlap). Contains Pfam match to entry PF00551 FT formyl_transf, Formyl transferase" FT /db_xref="GOA:Q9RK07" FT /db_xref="HSSP:1NJS" FT /db_xref="InterPro:IPR015518" FT /db_xref="UniProtKB/TrEMBL:Q9RK07" FT /protein_id="CAB53329.1" FT /translation="MRVVMFGYQTWGHRTLRALLDSEHDVVLVVTHPRSEHAYEKIWSD FT SVADLAEEHGVPVLIRNRPDDDELFERLKDADPDIIVANNWRTWIPPRIFGLPRHGTLN FT VHDSLLPKYAGFSPLIWALINGETEVGVTAHMMNDELDAGDIVRQEAVPVGPADTATDL FT FHKTVDLIAPVTVGALGLIASGQTEFTKQDRSRASFFHKRSAEDIRIDWNWPAEDLERL FT VRAQSEPYPSAFTFHRGRRLEILAAVVSEARYGGTPGRIFYREGEDVVIVAGADARRGR FT NHGLAITRVRTEDGRELAATEYFTSMGGYLTARP" FT CDS complement(234534..234773) FT /transl_table=11 FT /gene="SCO0500" FT /gene_synonym="SCF34.19c" FT /product="hypothetical protein SCF34.19c" FT /note="SCF34.19c, unknown, len: 79 aa; unknown function, FT probable CDS suggested by GC frameplot, positional base FT preference, amino acid composition and the presence of a FT potential RBS" FT /db_xref="UniProtKB/TrEMBL:Q9RK06" FT /protein_id="CAB53330.1" FT /translation="MTEESSSQTGSEPAEAEGTALTPDADGQYNLKDKFREALERKRGK FT QAEAAALAANADVAKIRGTHGPAASQRSFRRKSG" FT RBS complement(234779..234784) FT /note="possible RBS" FT CDS complement(234812..236764) FT /transl_table=11 FT /gene="SCO0501" FT /gene_synonym="SCF34.20c" FT /product="putative secreted protein" FT /note="SCF34.20c, putative secreted protein, len: 650 aa; FT unknown function, shows very weak similarity to FT SW:Y0D8_MYCTU (EMBL:Z78020) Mycobacterium tuberculosis FT hypothetical protein (628 aa), fasta scores; opt: 233 FT z-score: 232.7 E(): 1.3e-05, 23.6% identity in 512 aa FT overlap. Contains PS00017 ATP/GTP-binding site motif A FT (P-loop)" FT /db_xref="GOA:Q9RK05" FT /db_xref="InterPro:IPR013736" FT /db_xref="UniProtKB/TrEMBL:Q9RK05" FT /protein_id="CAB53331.1" FT /translation="MIAPHRRAGTSLLDLHHPYHLHPPSKEEHVRPRRAVARTASALVA FT ALALTVGLGGPAVAAHEAEAGPATTGTGSVTHEENDRVPEGSVWTQHYFPSADRSGTRL FT HADVLLPEGLKRKEKVPVILSIGPYFAHAGQTGPEGWSRTGPSARFQDFIEGTDLFDEG FT YAFVMVDLRGFGGSTGCLDWGGPGEQADVKAAIDWAAKQPWSTGAVGMYGKSYDAVTGL FT IGNNLDQRALRAVVAQEPVWDMYQYIYSNGVPRPNVTGTAGAYNSIASMPPMADDDPRY FT QAAARYEESHPECLTENSAGYRISDQRDPHWTSRDLARMARGSDTPLFVTQGFVENNTK FT PEEMEEYLDNHRGPERGWLGQWDHVRGGDRVEDGRLAMGRAGWYDETLSFYDQYLKGTR FT PTVRYPAYAVEDSTGAWRAQRTWPVTERTVTLPLGGGSYVDDGGASARAALTASGSPAP FT KAPPQPAGRWDMENAPATEQPAPAGLAAELAKRQRAGEVASSFFVWSKPLKSTTRVTGT FT PRVSLTARGAGNVMLKLYDVAPDGTAVMFDEQVSLVKSGRMSVDLKATDWTLAAGHVLA FT VEIGSIQTGSWRDTPSGETVEVKGARLGLALDNPADDVATAGDRSPYLDTYLRQYTVSL FT PAGPGTFSVVPGGRS" FT misc_feature complement(236120..236143) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT RBS 236958..236962 FT /note="possible RBS" FT CDS 236974..237408 FT /transl_table=11 FT /gene="SCO0502" FT /gene_synonym="SCF34.21" FT /product="putative membrane protein" FT /note="SCF34.21, possible membrane protein, len: 144 aa; FT unknown function, probable CDS suggested by GC frameplot FT and positional base preference. Contains hydrophobic, FT possible membrane-spanning regions" FT /db_xref="InterPro:IPR019099" FT /db_xref="UniProtKB/TrEMBL:Q9RK04" FT /protein_id="CAB53332.1" FT /translation="MARGVESIRRTALGALGAVLLLIGVALLVLPGPGLLLVFAGVVLL FT ARAVPALDRFVAPVRVRAMRAAEESVSSRWRIAGSVLVGLFLLAAGAAWGLVPELPYSG FT WATGASLIISGFVLFALLGWSHRRVRAARRGSPPASEGTR" FT CDS 237532..238512 FT /transl_table=11 FT /gene="SCO0503" FT /gene_synonym="SCF34.22" FT /product="hypothetical protein" FT /note="SCF34.22, hypothetical protein, len: 326 aa; unknown FT function, shows weak similarity to the N-terminal half of FT SCH10.22C (EMBL:AL049754) Streptomyces coelicolor putative FT lipase/esterase (301 aa), fasta scores; opt: 178 z-score: FT 202.4 E(): 0.00065, 30.1% identity in 163 aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9RK03" FT /protein_id="CAB53333.1" FT /translation="MSAQTHPTDFVPASAPVLSVAPVVLPAPGRPVDLRLRVSAPVTGT FT GLPVILLSHGQGYSNHLSSLDGYAPLATYWAAHGFVVIQPTHLSSRTLALDPGTPGAPL FT FWRSRAEDMTRVLDGLDLLEKAVPQLSGRLDRSRVAVAGHSMGGHTASLLLGARLTDPD FT DGTEVDLTEPRIGAGVLLAAPGRGGDALSESAAESMPFFLSTDFSRMTTPALVVAGDRD FT DSAHLTVSGPEWHTDPYSLSPGPKSLLTLFGAEHGLGGVAGYDVAETTDEDPGRVAAVQ FT RLTWAYLRSTLYPGDTAWQVARDALDSGPDPLGRVESKQAPHPRP" FT CDS 238623..239942 FT /transl_table=11 FT /gene="SCO0504" FT /gene_synonym="SCF34.23" FT /product="putative DEAD-box RNA-helicase" FT /note="SCF34.23, probable DEAD-box RNA-helicase, len: 439 FT aa; similar to many e.g. to TR:O64430 (EMBL:AB010259), FT Drh1, Arabidopsis thaliana DEAD box ATPase/RNA helicase FT protein (619 aa), except where the A.thaliana protein is FT longer at the N-terminus, fasta scores; opt: 806 z-score: FT 892.9 E(): 0, 35.3% identity in 447 aa overlap. Also FT similar to many putative RNA-helicases e.g. SW:RHLE_ECOLI FT (EMBL:L02123), RhlE, Escherichia coli putative FT ATP-dependent RNA helicase (454 aa) (36.4% identity in 451 FT aa overlap) and to TR:O54116 (EMBL:AL021529) Streptomyces FT coelicolor probable DEAD-box RNA-helicase (498 aa) (67.7% FT identity in 424 aa overlap). Contains Pfam matches to entry FT PF00270 DEAD, DEAD/DEAH box helicase and to entry PF00271 FT helicase_C, Helicases conserved C-terminal domain. Contains FT 2 PS00017 ATP/GTP-binding site motif A (P-loop)" FT /db_xref="GOA:Q9RK02" FT /db_xref="HSSP:1QDE" FT /db_xref="InterPro:IPR014021" FT /db_xref="UniProtKB/TrEMBL:Q9RK02" FT /protein_id="CAB53334.1" FT /translation="MNAKPTASFDGLGLPPVLVETMTSLGVTRPFPIQAATLPEALAGR FT DVLGRARTGSGKTLAFGLALLAGTAGRRAEPKRPLALVLVSTRELAQQVSDALAPYARA FT LGVRLTTVVGGLSINRQTQALRDGAEVVVATPGRLTDLVSRRDCHLNQVRITVLDEADQ FT MCDLGFLPQVSGILDQVPSDGQRLLFSATLDGDVDQLVRDHLHDPVPVSVDPASASVST FT MEHHVLTVHPADKYATATEIAARDGRVLMFLDTKAGVDRFTRELRAAGVSAGALHSGKS FT QPQRTHTLARFVEGGVTVLVATNVAARGIHVDDLDLVVNVDPPADAKDYLHRGGRTARA FT GRAGSVVTLVTPDQRREVNRMMSEAGIRPTVTPVRSGEQKLTDLTGAKRPPAGRGKESG FT NAPFRGMGTRPAGAAKGSRKAVEARRAAEARAAARVRKGR" FT misc_feature 238680..239315 FT /note="Pfam match to entry PF00270 DEAD, DEAD/DEAH box FT helicase, score 165.20, E-value 2.6e-51" FT misc_feature 238773..238796 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 239400..239645 FT /note="Pfam match to entry PF00271 helicase_C, Helicases FT conserved C-terminal domain, score 101.10, E-value 2.1e-26" FT misc_feature 239442..239465 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 240123..243131 FT /transl_table=11 FT /gene="SCO0505" FT /gene_synonym="SCF6.01" FT /gene_synonym="SCF34.24" FT /product="putative large, multifunctional secreted protein" FT /note="SCF6.01, possible multi-domain protein, (fragment), FT len: >152 aa. Highly similar to Amycolatopsis orientalis FT TR:CAB45032 (EMBL; AL078635) putative large FT multi-functional protein (987 aa), fasta scores opt: 595 FT z-score: 714.7 E(): 1.9e-32 58.6% identity in 152 aa FT overlap." FT /note="SCF34.24, possible large, multifunctional secreted FT protein, partial CDS, len: >891 aa; contains a region of FT weak similarity to members of the glycosyl hydrolase family FT at approx. aa 700-890 e.g. to part of SW:CTA2_BACCI FT (EMBL:D88360), Cit, Bacillus circulans FT cycloisomaltooligosaccharide glucanotransferase precursor FT (964 aa), fasta scores; opt: 279 z-score: 292.6 E(): FT 6.1e-09, 33.3% identity in 213 aa overlap and region of FT very weak similarity at approx. aa 200-400 to part of a FT dehydrogenase SW:SNDH_ACELI (EMBL:D28511) Acetobacter FT liquefaciens L-sorbosone dehydrogenase (449 aa) (26.2% FT identity in 279 aa overlap). Similar to CZA382.11 FT (EMBL:AL078635) Amycolatopsis orientalis possible large, FT multifunctional protein (987 aa) (63.2% identity in 880 aa FT overlap). Contains a probable N-terminal signal sequence" FT /db_xref="GOA:Q8CK54" FT /db_xref="InterPro:IPR011658" FT /db_xref="UniProtKB/TrEMBL:Q8CK54" FT /protein_id="CAD55445.1" FT /translation="MHPRLFSRARRHLILLLTSAVALGGAWAAPASSAAPADIPPQEPG FT VTLRVFDVQTPLNELCTLKPGQTPNHDKLMPTVDWSTTADFGGIADNFVSQASGYLVAP FT RDGTYVFRLVSDDGSRLALDGATVIDHDGLHGAEPKDGTVELTAGAHPLRIDHFDRGGG FT QQVQLSWMPPGESGFTVVPTEALSTDAGVVRVTAPGRKECEAGRDTPGDGLPLTSVRPD FT LDLTDLRPEGFEPQVTGMDWLPDGRLAISTWGGTDNVAGEVYLLDNVTGETSRDKVTVE FT KVASGLREPMGIKYVDGSLYVSQKHELTRLVDSDGDDVTDEYRTVATWPYGGNFHEFAF FT GLLYRDGYFYVNLSVAIDLGGATTNPQPAPNRGTTYKISKKTGKISPIAGGLRTPNGIG FT WGPGGSLFATDNQGGWLPASKLVQIKQDRFFNHYTEPAGPFEDSPVTEPVLWLPQNEIG FT NSPSTPLYLTKGRFAGQLLIGDVTYGGLQRAYLEKVKGQYQGAVFRYTQGLEAGVNRVS FT MGPDGAIYTGGLGADGNWGQEGKLKFGLQKLTPNGGNTFDVQKMRAVPGGFDLTYTQPV FT SEATAAELASRYEAEQWRYTPTGDYGGPKIAEEELAVRSATLSDDGRTVRLRLDGLKPD FT RVVHVRSPRPFTSASGETLWSTEAWYTLNEMPGKQPPAATLYEAEEARLTGKAGINTDH FT IGYSGSGFVDRYATEGDVTTTFDVTVPRAGTYDVGLRYSNGPDPFEGTKSLSLYAGGKK FT VRQTQLPSTGDWDTWSTRTESVRLRAGHNTVSYRYDPGDTGHVNLDLITVRPHGARVAL FT FDGTAASQEQWQHTDGRKAAWPLAEERSMEVCCGDIRTKDAYQDFKLHVEFRVPLLPDD FT VTGQDRGNSGIYLQDRYELQILDSYGDTTLDTNEAGAIYLKKAPDTNAATAPETWQTYD FT IVFRAARFDENGAKTADARVTVVWNGETVHDDVALDGPTAAGRAETPAAGAIRLQDHGN FT KVRFRDIRVEPLN" FT RBS 243258..243263 FT CDS 243269..244099 FT /transl_table=11 FT /gene="SCO0506" FT /gene_synonym="nadE1" FT /product="NH(3)-dependent NAD(+)synthetase" FT /note="SCF6.02, nadE1, probable NH(3)-dependent FT NAD(+)synthetase, len: 276 aa. Highly similar to many e.g. FT Bacillus subtilis SW: NADE_BACSU (EMBL; M15811) FT NH(3)-dependent NAD(+) synthetase (EC 6.3.5.1) (spore FT outgrowth factor B) (sporulation protein OutB) (general FT stress protein 38) (Gsp38) (272 aa), fasta scores opt: 901 FT z-score: 1027.2 E():0 53.9% identity in 267 aa overlap." FT /db_xref="GOA:Q9RJM5" FT /db_xref="HSSP:1IH8" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/Swiss-Prot:Q9RJM5" FT /protein_id="CAB58266.1" FT /translation="MSEPASIALQKEIVRELEVAETFDAEREIERRVAFLAERLTSTGL FT RALVLGISGGVDSTTAGRLCQLAVERARAAGHEALFYAMRLPHGVQADEDDAQQALSFI FT RPDRVLTVDIKPASDAALDALLAADVAFRDPHHQDFVHGNIKARQRMIAQYAVAGAHGG FT LVVGTDHAAEAVSGFFTKFGDGAADVVPLTGLTKRRVRAVGDALGAPAALVRKVPTADL FT ETLDPGKADEDALGVTYEEIDDFLEGKPVTEQVFETIVTRYRQTDHKRRLPIAP" FT stem_loop 244021..244110 FT /note="possible stem loop consisting of 90 bp with a 28 bp FT inverted repeat." FT CDS complement(244119..244535) FT /transl_table=11 FT /gene="SCO0507" FT /gene_synonym="SCF6.03c" FT /product="hypothetical protein SCF6.03c" FT /note="SCF6.03c, unknown, len: 138 aa. Similar to the FT C-terminus of many hypothetical oxidoreductases e.g. FT Streptomyces coelicolor TR: CAB53280 (EMBL; AL109972) FT putative oxidoreductase SCJ9A.19C (311 aa), fasta scores FT opt: 307 z-score: 331.8 E(): 4.1e-11 44.4% identity in 126 FT aa overlap." FT /db_xref="GOA:Q9RJM4" FT /db_xref="InterPro:IPR002198" FT /db_xref="UniProtKB/TrEMBL:Q9RJM4" FT /protein_id="CAB58267.1" FT /translation="MAFCNQSKFANAVFGQELHRRLAETGSPVRSALAHPGYSATGPQT FT SAPAGMVRMLFGRVPRPLARSAERGALPRLYAAADPGVRGGGFIGPDGPGELRGGPKRV FT RLSPAAADAATGRSLWELSERLTGVGFPPGPATG" FT CDS 244545..245087 FT /transl_table=11 FT /gene="SCO0508" FT /gene_synonym="SCF6.04" FT /product="putative tetR family transcriptional regulator" FT /note="SCF6.04, possible tetR family transcriptional FT regulator, len: 180 aa. Similar to many e.g. Streptomyces FT glaucescens SW:TCMR_STRGA (EMBL:M80674) tetracenomycin C FT transcriptional repressor (226 aa), fasta scores opt: 225 FT z-score: 288.9 E(): 1e-08 34.5% identity in 174 aa overlap. FT Contains a Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family with the possible FT helix-turn-helix motif between residues 13..34 (+3.92 SD)." FT /db_xref="GOA:Q9RJM3" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9RJM3" FT /protein_id="CAB58268.1" FT /translation="MALAGEVVGEEVTTDEIASAAGVSKRTFFRYFASKEDVVVRFLTD FT MGAGIHRELAARPAGERPSLALRSVLSGPLAACADHSDRALRVVRLILRTPALHARLLE FT RQGRWREGLAAELARRPDLGPDHELYPELAAGMALTAFNTVLHRWSDSDGTADPEALTE FT QAFALIAPALDGTRRQT" FT misc_feature 244572..244670 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 33.70, E-value FT 1.3e-07" FT CDS 245194..246717 FT /transl_table=11 FT /gene="SCO0509" FT /gene_synonym="glpK2" FT /product="glycerol kinase 2 (ATP:glycerol FT 3-phosphotransferase) (EC 2.7.1.30)" FT /note="SCF6.05, glpK2, glycerol kinase (ATP:glycerol FT 3-phosphotransferase)(EC 2.7.1.30), len: 507 aa. Highly FT similar to many glycerol kinases e.g. Mycobacterium FT tuberculosis TR: O69664 (EMBL; AL022121) (517 aa), fasta FT scores opt: 2606 z-score: 3028.8 E(): 0 75.3% identity in FT 503 aa overlap and Haemophilus influenzae SW:GLPK_HAEIN FT (EMBL; U32752) (502 aa), fasta scores opt: 1714 z-score: FT 1992.5 E():0 51.1% identity in 503 aa overlap. Contains FT Pfam match to entry PF00370 FGGY, FGGY family of FT carbohydrate kinases and Prosite hits to PS00933 FGGY FT family of carbohydrate kinases signature 1 and PS00445 FGGY FT family of carbohydrate kinases signature 2. Also contains a FT possible membrane spanning hydrophobic domain." FT /db_xref="GOA:Q9RJM2" FT /db_xref="HSSP:1GLC" FT /db_xref="InterPro:IPR005999" FT /db_xref="UniProtKB/Swiss-Prot:Q9RJM2" FT /protein_id="CAB58269.1" FT /translation="MADFIGAVDQGTTSTRFMIFDHGGNEVAKHQLEHEQILPRSGWVE FT HDPVEIWERTNSVMQNALRNGGLSGTDLAAIGITNQRETTVVWDPRTGRPYYNAIVWQD FT TRTDAIAANLERSGRGDVIRRKAGLPPATYFSGGKIQWILENVDGVREAAEQGHAVFGN FT TDSWVLWNLTGGPDGGIHATDVTNASRTMLMNLETLDWDDELLGFFGIPRGMLPTINPS FT SHPEAFGTTRTSRPLRAAVPITGVLGDQHAATVGQVCFSPGEAKNTYGTGNFLVLNTGT FT ELVRSQHGLLTTVAYQFGDNPPVYALEGSIAVTGSAVQWLRDQMKIIKTAAESEELART FT VEDNGGMYFVPAFSGLFAPYWRSDARGAIVGLARYNDNAHLARATLEAICYQSRDVVVA FT MEQDSSVHLDVLRVDGGVTANDLCMQIQADILGVPVSRPVVAETTALGAAYAAGLATGF FT WRHTDELRTHWSESRRWEPQWSEERRAQGYAGWKMAVERTLDWVKVPES" FT misc_feature 245419..246540 FT /note="Pfam match to entry PF00370 FGGY, FGGY family of FT carbohydrate kinases, score 419.50, E-value 3.2e-122" FT misc_feature 245593..245631 FT /note="PS00933 FGGY family of carbohydrate kinases FT signature 1" FT misc_feature 246292..246354 FT /note="PS00445 FGGY family of carbohydrate kinases FT signature 2" FT CDS complement(246740..247147) FT /pseudo FT /transl_table=11 FT /gene="SCO0510" FT /gene_synonym="SCF6.06c" FT /product="putative oxidoreductase (pseudogene)" FT /note="SCF6.06c, putative oxidoreductase, pseudogene, len: FT 83 aa. Similar to parts of Streptomyces lividans FT SW:OXIR_STRLI probable oxidoreductase (EC 1.-.-.-) (297 aa) FT and Streptomyces antibioticus SW:OXIR_STRAT (EMBL; M96551) FT probable oxidoreductase (EC 1.-.-.-) (298 aa). This CDS has FT at least one frame shift in the sequence after residue 35, FT nucleotide position 4371." FT RBS 247341..247345 FT CDS 247358..248116 FT /transl_table=11 FT /gene="SCO0511" FT /gene_synonym="SCF6.07" FT /product="putative dehydrogenase (putative secreted FT protein)" FT /note="SCF6.07, possible dehydrogenase (putative secreted FT protein), len: 252 aa. Highly similar to many e.g. FT Pseudomonas paucimobilis SW:LINX_PSEPA (EMBL; D23722) FT 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase (EC FT 1.1.-.-) (2,5-ddol dehydrogenase) LinX (250 aa), fasta FT scores opt: 532 z-score: 558.4 E(): 9.7e-24 40.0% identity FT in 245 aa overlap. Also similar to many Streptomyces FT coelicolor putative oxidoreductases e.g. TR:O88068 (EMBL; FT AL031541) putative dehydrogenase SCI35.33C (260 aa), fasta FT scores opt: 488 z-score: 438.3 E(): 4.1e-19 38.7% identity FT in 256 aa overlap. Contains a Prosite hit to PS00061 FT Short-chain dehydrogenases/reductases family signature and FT Pfam hits to entry PF00678 adh_short_C2, Short chain FT dehydrogenase/reductase C-terminus and Pfam match to entry FT PF00106 adh_short, short chain dehydrogenase." FT /db_xref="GOA:Q9RJM1" FT /db_xref="HSSP:1E7W" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RJM1" FT /protein_id="CAB58271.1" FT /translation="MRLADRTALVTGATSNIGRAIAEAFAAEGAHVVVSGRSAERGREV FT VDGIRAAGGRADFVHADLDGSAAASRALAREATRVLGGRVDVLVNNAGIYPPGTTTDTD FT EETFDRVYAVNVKAPFFLTAVLAPAMVRAGGGTVINLGSWIARLGVPVGALYSSTKGAV FT ETLTRAWAAEFGARGVRVNAISPGVVQTPPPGEVHPAEVMMRGTPAGRMGTPEAIASAA FT VYLAGDESSFVHGTVLDVDGGRTAAAVIAA" FT misc_feature 247373..247933 FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 217.30, E-value 2.3e-61" FT misc_feature 247784..247870 FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT misc_feature 247985..248077 FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 42.80, FT E-value 7.7e-09" FT CDS complement(248135..248743) FT /transl_table=11 FT /gene="SCO0512" FT /gene_synonym="SCF6.08c" FT /product="putative regulatory protein" FT /note="SCF6.08c, possible regulatory protein, len: 202 aa. FT Similar to many other putative regulatory proteins e.g. FT Streptomyces coelicolor TR:CAB53122 (EMBL; AL109962) FT putative transcriptional regulatory protein SCJ1.04 (207 FT aa), fasta scores opt: 436 z-score: 515.3 E(): 2.5e-21 FT 44.4% identity in 196 aa overlap." FT /db_xref="GOA:Q9RJM0" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9RJM0" FT /protein_id="CAB58272.1" FT /translation="MRGELTAKGRATRRRIVEGAAAVLRERGVASTTLDDIMARTATSK FT SQLFHYFPAGKDELLVEVARFEADQVLEDQQPQLGRLDSWEAWREWRDVVIERYETQGD FT QCPLGSLFLQIGRSTPGTRAIVVELLRQWQESLAAGIRSLQGAGALPADLDVETRAAAL FT LTAIQGGVSILLSTGRSTHLRAALDQGIADLRRAGAAAR" FT RBS complement(248751..248755) FT CDS 248809..249900 FT /transl_table=11 FT /gene="SCO0513" FT /gene_synonym="SCF6.09" FT /product="integral membrane protein" FT /note="SCF6.09, integral membrane protein, len: 363 aa. FT Similar to a number of hypothetical integral membrane FT proteins e.g. Escherichia coli SW:PERM_ECOLI (EMBL; FT AE000335) putative permease PerM (353 aa), fasta scores FT opt: 383 z-score: 425.2 E(): 2.6e-16 27.5% identity in 346 FT aa overlap and Mycobacterium tuberculosis TR:O53656 (EMBL; FT AL021928) hypothetical 38.0 KD protein (367 aa), fasta FT scores opt: 687 z-score: 755.9 E():0 33.5% identity in 340 FT aa overlap. Contains multiple possible membrane spanning FT hydrophobic domains and a Pfam match to entry PF01594 FT DUF20, Putative permease." FT /db_xref="InterPro:IPR002549" FT /db_xref="UniProtKB/TrEMBL:Q9RJL9" FT /protein_id="CAB58273.1" FT /translation="MSAGLSAAKTRAALRTSARVSGELLLILVMLAVTLWVLGRMWSVV FT WPLLVGLLLTTLTWPPARFLRRHGWRPALAATVVTVAFLLVVLGIVALIAVPMSSQTDE FT LTDGVVEGIQRLREWAAGPPLNIGDDEITGAMDSAVARIQDSVGSITTAVATGVGAVVN FT GLITAVLGVFLMFFFLKDGPRFLPWLARQLPGRLATDVPVVALRGWETLGSFVRSQALV FT GLLDAVFIGLGLWILGVPLVLPLAVLTFVSAFVPIVGALFAGFVAVLIALVSNGLTDAL FT IVLAIIVVVQQLEGNVFQPILQSRGLGLHAAVILLAVTLGGSLSGIVGSLLAVPFAALI FT AVVWTYVREQLSERPEATATADG" FT misc_feature 248896..249852 FT /note="Pfam match to entry PF01594 DUF20, Putative FT permease, score 161.60, E-value 1.3e-44" FT CDS 249968..250621 FT /transl_table=11 FT /gene="SCO0514" FT /gene_synonym="SCF6.10" FT /product="hypothetical protein SCF6.10" FT /note="SCF6.10, unknown, len: 217 aa." FT /db_xref="UniProtKB/TrEMBL:Q9RJL8" FT /protein_id="CAB58274.1" FT /translation="MDLFSRSWSALLAAVAGLCDEDFARPSGCAGWLVRDLVCHLVVDA FT QDVLITLATPTADEPTRDAVTYWQVVEPPTGDDPLDALIVRLAAAYEQPGLLKFHLADV FT GSAAGRAAALADPASRVGTQGQVLTAGDYLSAYVLECSLHHLDLIAHLPEAAPPPAAGL FT RRSRELLERVVGTAFPTVFADRDALLIGTGRRAPTPAEEAALGELAARLPFPVG" FT CDS 250850..251458 FT /pseudo FT /transl_table=11 FT /gene="SCO0515" FT /gene_synonym="SCF6.11" FT /product="hypothetical protein SCF6.11 (pseudogene)" FT /note="SCF6.11, unknown, pseudogene, len: 128 aa. Similar FT to Escherichia coli SW:YAHD_ECOLI (EMBL; AE000139) FT hypothetical 21.7 KD protein in BETT-PRPR intergenic region FT (201 aa). The high similarity extends past the last FT possible translational start codon suitable for this CDS." FT CDS 251455..252633 FT /transl_table=11 FT /gene="SCO0516" FT /gene_synonym="SCF6.12" FT /product="putative lipoprotein" FT /note="SCF6.12, possible lipoprotein, len:392 aa. Weakly FT similar to Methylobacterium extorquens TR:O30796 (EMBL; FT AF017434) hypothetical protein MxaE (281 aa), fasta scores FT opt: 205 z-score: 214.7 E(): 0.00014 32.5% identity in 295 FT aa overlap. Contains a possible N-terminal signal sequence FT and an appropriately positioned Prosite hit to PS00013 FT Prokaryotic membrane lipoprotein lipid attachment site." FT /db_xref="InterPro:IPR015943" FT /db_xref="UniProtKB/TrEMBL:Q9RJL7" FT /protein_id="CAB58276.1" FT /translation="MNRRSLAGRLAALAAVTATLGGCAPDGGDDGAASPVSAPPGSTAQ FT RTPGSGGTSARTPQGTLLVTDFGADTVTFVDPAGRGAAADLGSVRVGTAPYGIALGEDG FT TAWVATAEGVAAVDTRTRVRTALVPHRTDTGPVTTGEYRGGGMGIALSPDGSRVYVGVN FT VPGGKGTLEVVDTERREVTRVVPVGRRPFDVDVSRDGRQVYATNHDSFDVSVVDTGDWT FT ARRIEVAPYGTEGGLGSWLKPHYAAVRPSDGALLLPFEGERLAVVDPGTGRVRTEDMTA FT NTHQHGVTAGADGTLYVVGTGPIDPSEDDGPSLTVRTPEGDERVVPLDGPHETVALSAD FT GRTAYVSGGFTRDGYWNGLSAVDVATGRVTRLPVGERPLAVAVLGGQGTGAG" FT misc_feature 251491..251523 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS <252918..>253115 FT /transl_table=11 FT /gene="SCO0517" FT /gene_synonym="SCF6.13" FT /product="hypothetical protein" FT /note="SCF6.13, hypothetical protein, len: 66 aa. Gene FT fragment shares a high level of similarity with FT Streptomyces coelicolor TR:CAB53135 (EMBL; AL109962) FT possible regulator protein SCJ1.17 (190 aa); fasta scores: FT opt: 275 z-score: 356.5 E(): 1.7e-12; 62.1% identity in 66 FT aa overlap" FT /db_xref="UniProtKB/TrEMBL:Q9ADB0" FT /protein_id="CAB58277.2" FT /translation="RVVRVAREVRVAEGTRLFEEGRRAELFRIVRTRTVGLDLRVPGRR FT SPVVETPGHGELVGWCWHFPP" FT CDS 253094..>253351 FT /transl_table=11 FT /gene="SCO0518" FT /gene_synonym="SCF6.14" FT /product="hypothetical protein" FT /note="SCF6.14, hypothetical protein, len: 86 aa. Gene FT fragment that is highly similar to Streptomyces coelicolor FT TR:Q9RI29 (EMBL:AL109989) putative nitrate reductase delta FT chain NarI2 (256 aa); fasta scores: opt: 409 Z-score: 526.8 FT bits: 103.5 E(): 9.3e-22; 74.390% identity in 82 aa FT overlap" FT /db_xref="GOA:Q9ADA9" FT /db_xref="HSSP:1Q16" FT /db_xref="InterPro:IPR003816" FT /db_xref="UniProtKB/TrEMBL:Q9ADA9" FT /protein_id="CAB58278.2" FT /translation="MVLALPAGGGYDYRGTVSVWFRGLFALGPRPEVIAYAPLLFRPHA FT PSACLLFAARPFTRLVHVWSAPVGYLVRPCSVHRRRATPAR" FT CDS complement(253403..254140) FT /transl_table=11 FT /gene="SCO0519" FT /gene_synonym="SCF6.15c" FT /product="putative oxidoreductase" FT /note="SCF6.15c, possible oxidoreductase, len: 245 aa. FT Similar to many e.g. Bacillus megaterium SW:DHG2_BACME FT (EMBL; D90044) glucose 1-dehydrogenase II (EC 1.1.1.47) FT (GLCDH-II) (261 aa), fasta scores opt: 402 z-score: 449.5 FT E(): 1.1e-17 35.1% identity in 228 aa overlap. Also similar FT to many other Streptomyces coelicolor putative FT oxidoreductases e.g. TR:CAB41284 (EMBL; AL049707) (260 aa), FT fasta scores opt: 395 z-score: 365.3 E(): 4.8e-15 37.2% FT identity in 242 aa overlap. Contains a Pfam match to entry FT PF00106 adh_short, short chain dehydrogenase and a Prosite FT hit to PS00061 Short-chain dehydrogenases/reductases family FT signature." FT /db_xref="GOA:Q9RJL6" FT /db_xref="HSSP:1GEE" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RJL6" FT /protein_id="CAB58279.1" FT /translation="MSGIEGKVVAITGASGGIGEASALLLAERGAKVVLGARRPERLAD FT LALRIGRSGGEAAWIRTDVTRREDVAALVALARERFGRLDVLVGNAGVGLISPLDELRV FT EDWERMIDVNLKGVLYGIAEALPVFREQGSGHFVNIVSTAGLRISPLMSVYAGTKNAVR FT TVSEGLRQEAGDSLRVTVVSPGFVHTDFADGIPDAGARAQILDTRDRVAIPPQAVARAV FT AFAVEQPDGVDVGDIVVRPTAQD" FT misc_feature complement(253571..254122) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 199.00, E-value 7.2e-56" FT misc_feature complement(253631..253717) FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT RBS 254262..254267 FT CDS 254277..254861 FT /transl_table=11 FT /gene="SCO0520" FT /gene_synonym="SCF6.16" FT /product="putative tetR family transcriptional regulator" FT /note="SCF6.16, putative tetR family transcriptional FT regulator, len: 194 aa. Weakly similar to many other tetR FT family regulators e.g. Streptomyces sp. TR:O24741 FT (EMBL:AB001683) FarA (221 aa), fasta scores opt: 161 FT z-score: 205.5 E(): 0.00044 28.4% identity in 190 aa FT overlap and Streptomyces coelicolor TR:O86852 FT (EMBL:AJ007731) gamma-butyrolactone binding protein (215 FT aa), fasta scores opt: 149 z-score: 191.2 E(): 0.0028 FT 26.6% identity in 188 aa overlap. Also highly similar to FT Streptomyces coelicolor SCF51A.08 (EMBL; AL121596) putative FT tetR family transcriptional regulator (227 aa), fasta FT scores opt: 479 z-score: 463.7 E(): 1.5e-20 43.7% identity FT in 183 aa overlap. Contains a Pfam match to entry PF00440 FT tetR, Bacterial regulatory proteins, tetR family. The FT possible helix-turn-helix motif lies between residues FT 36..57 (+4.21 SD)." FT /db_xref="GOA:Q9RJL5" FT /db_xref="InterPro:IPR012287" FT /db_xref="PDB:2Q24" FT /db_xref="UniProtKB/TrEMBL:Q9RJL5" FT /protein_id="CAB58280.1" FT /translation="MSDATKRPLRADAQRNRDKILAAAVRVFSEEGLDAHLERIAREAG FT VGSGTLYRNFPTREALIEAAYRNEVARLCDSVPGLLAELPPAEALRAWTRRFIDYATAK FT LGMADALRAVVASGGDPYGDSRQLIQSALTALMDAAAAAGEIRSDIRSTDMFAALAGIA FT LTSSRPDQRAQAERLLDLVLDGLRPTAPRPA" FT misc_feature 254334..254471 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 31.00, E-value FT 7.1e-07" FT CDS 254892..255473 FT /transl_table=11 FT /gene="SCO0521" FT /gene_synonym="SCF11.01" FT /gene_synonym="SCF6.17" FT /product="putative TetR family transcriptional regulator" FT /note="SCF11.01, possible tetR family transcriptional FT regulator, partial CDS, len: >32 aa. Previously annotated FT as Streptomyces coelicolor SCF6.17, possible tetR family FT trasncriptional regulator, len: >193 aa. Similar to several FT e.g. Streptomyces coelicolor TR:CAB56142 (EMBL; AL117669) FT putative transcriptional regulator SCF12.15 (188 aa), fasta FT scores opt:446 z-score: 521.2 E(): 1.2e-21 43.5% identity FT in 184 aa overlap and Streptomyces glaucescens FT SW:TCMR_STRGA (EMBL; M80674) tetracenomycin C FT transcriptional repressor (226 aa), fasta scores opt: 202 FT z-score: 242.5 E(): 3.8e-06 29.3% identity in 164 aa FT overlap." FT /note="SCF6.17, possible tetR family transcriptional FT regulator, len: 193 aa. Similar to several e.g. FT Streptomyces coelicolor TR:CAB56142 (EMBL; AL117669) FT putative transcriptional regulator SCF12.15 (188 aa), fasta FT scores opt:446 z-score: 521.2 E(): 1.2e-21 43.5% identity FT in 184 aa overlap and Streptomyces glaucescens FT SW:TCMR_STRGA (EMBL; M80674) tetracenomycin C FT transcriptional repressor (226 aa), fasta scores opt: 202 FT z-score: 242.5 E(): 3.8e-06 29.3% identity in 164 aa FT overlap. Contains a Pfam match to entry PF00440 tetR, FT Bacterial regulatory proteins, tetR family. The possible FT helix-turn-helix motif lies between residues 29..50 (+2.70 FT SD)." FT /db_xref="GOA:Q9RJL4" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9RJL4" FT /protein_id="CAB58281.1" FT /translation="MGRWEPNARGRLEQAALELYVERGYEQTPVAEITKRAGLTERTFF FT RHFTDKREVLFAGSGRLEELCVAAVAAAPTTASPMEAVAAALDAAAGAFEERGDLVGLR FT QGVIDSNAELRERELIKLASLSGALADALRGRGVAEPAAELTAESAIAVLKVAFRRWID FT GGRERPLRPLLAECFDVLRTLSARGAASAG" FT misc_feature 254925..255056 FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 37.70, E-value FT 1e-08" FT RBS 255627..255630 FT CDS 255649..256440 FT /transl_table=11 FT /gene="SCO0522" FT /gene_synonym="SCF11.02" FT /product="putative oxidoreductase" FT /note="SCF11.02, probable oxidoreductase, len: 262 aa; FT similar to TR:O54197 (EMBL:AJ000671) Streptomyces FT clavuligerus clavulanate-9-aldehyde reductase, 247 aa; FT fasta scores: opt: 501 z-score: 567.7 E(): 3e-24; 39.1% FT identity in 238 aa overlap. Contains Pfam match to entry FT PF00106 adh_short, short chain dehydrogenase and prosite FT match to entry PS00061 Short-chain FT dehydrogenases/reductases family signature. also similar to FT Streptomyces coelicolor SCF6.15c, 245 aa; fasta scores: FT opt: 818 z-score: 805.2 E():0; 56.5% identity in 237 aa FT overlap" FT /db_xref="GOA:Q9RK87" FT /db_xref="HSSP:1FDS" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RK87" FT /protein_id="CAB59579.1" FT /translation="MSRTDSAQQMRTIHRKDIVMTQTSKVVLVTGASSGIGEATALRLA FT ADGHRVFLGARRTERLEKLAARIAEDGGTAGYRRLDVTDAADVRAFVSAAVERWGRLDV FT IVNNAGVMPLSPLSELKVAEWDRMLDVNVRGVLHGIAAALPVMRAQGGGHVVNIASVGA FT YEVVPTAAVYCATKFAVRALSEGLRQESAGDIRVSVVSPGVTESELADSISDPRAREDM FT KTYRSVAVPASAIADAIAFAVSRPAEVDVNEIVVRPAASAQ" FT misc_feature 255721..256272 FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 248.20, E-value 1.2e-70" FT misc_feature 256126..256212 FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT CDS complement(256468..256905) FT /transl_table=11 FT /gene="SCO0523" FT /gene_synonym="SCF11.03c" FT /product="putative transcriptional regulator" FT /note="SCF11.03c, probable transcriptional regulator, len: FT 145 aa; similar to SW:ASNC_ECOLI (EMBL:AE000451) FT Escherichia coli, regulatory protein AsnC, 152 aa; fasta FT scores: opt: 222 z-score: 287.1 E(): 1.3e-08; 26.9% FT identity in 145 aa overlap. Contains Pfam match to entry FT PF01037 ASNC_trans_reg, AsnC family" FT /db_xref="GOA:Q9RK86" FT /db_xref="InterPro:IPR019888" FT /db_xref="UniProtKB/TrEMBL:Q9RK86" FT /protein_id="CAB59580.1" FT /translation="MDEIDRRLIALLQQDATRPYAALGGEVGLSAGAAHERVRKLREQR FT VIRSTTVDVDPEALDRGVLAFVLVDSTAWMGDRAEDFAAVPEIQEAHVIAGSAAVLVKV FT RTATTERLQDVLRRLYAIDGVSGTQATVVLETFFERPLDAG" FT misc_feature complement(256537..256833) FT /note="Pfam match to entry PF01037 ASNC_trans_reg, AsnC FT family, score 52.20, E-value 1.1e-11" FT RBS 256981..256985 FT CDS 256990..257898 FT /transl_table=11 FT /gene="SCO0524" FT /gene_synonym="SCF11.04" FT /product="possible gluconolactonase precursor" FT /note="SCF11.04, possible gluconolactonase, len: 302 aa; FT similar to SW:GNL_ZYMMO (EMBL:X67189) Zymomonas mobilis FT gluconolactonase precursor (EC 3.1.1.17) FT D-glucono-delta-lactone lactonohydrolase; fasta scores: FT opt: 326 z-score: 392.6 E(): 1.7e-14; 28.7% identity in 258 FT aa overlap" FT /db_xref="InterPro:IPR005511" FT /db_xref="UniProtKB/TrEMBL:Q9RK85" FT /protein_id="CAB59581.1" FT /translation="MSTDGPYEILDDRFRTGRCANGDNRLEVLYDGCRWAEGPLYLPAW FT RQLVWSDIPNDRILRWDEATGSVGVFRAPAGHSNGNTLDRQGRLVTCEQGNRRVTRTEP FT DGRVTVLAERFDGRRLNSPNDSVVRSDGTIWFSDPDFGITSDYEGHRAESEIGACNVYR FT IDPVSGQVRLAADGFDGPNGVILTPDERRLFVSDSRAARIHAFDIREDGTLSDGKVFAE FT GRGDVHFDNIRFDDEGRLWAAALHDGVHCYDPDGTLIGRLRVPEPVSNVAFGGPKNNRL FT FITATTSLYSLVMSVTGAPRL" FT CDS 258029..258844 FT /transl_table=11 FT /gene="SCO0525" FT /gene_synonym="SCF11.05" FT /product="conserved hypothetical protein SCF11.05" FT /note="SCF11.05, hypothetical protein, len: 271 aa; similar FT to various hypothetical proteins, e.g. TR:CAB45341 FT (EMBL:AL079345) Streptomyces coelicolor SCE68.05C FT hypothetical 33.1 KD protein, 300 aa; fasta scores: opt: FT 808 z-score: 960.4 E(): 0; 53.2% identity in 250 aa FT overlap" FT /db_xref="InterPro:IPR006764" FT /db_xref="UniProtKB/TrEMBL:Q9RK84" FT /protein_id="CAB59582.1" FT /translation="MSDPSTTPGHTAQQKIDTSVPHSARIWNYWLGGKDNYPVDEQAGD FT AYTAVFPGIVTVARSSRAFLRRNITHLVAEAGIRQFLDIGTGLPTADNTHEVAQRIAPE FT SRIVYVDNDPMVLAHARALLYSTPEGATSYIDSDVLDPDTVLEAAARTLDFDRPIALIL FT SNILGHIPDYDQARSVAARLVDALPSGSYLSINDGSRGIDPEFDRAQDGYNESGAAPYI FT LRTVDQITAFFDGLELVEPGVVPVTRWRPDADTEDPGLIGEHGGLARKP" FT RBS 258868..258872 FT CDS 258882..259715 FT /transl_table=11 FT /gene="SCO0526" FT /gene_synonym="SCF11.06" FT /product="possible oxidoreductase" FT /note="SCF11.06, possible oxidoreductase, len: 277 aa; FT similar to TR:O53622 (EMBL:AL021428) Mycobacterium FT tuberculosis putative oxidoreductase MTV030.21c, 276 aa; FT fasta scores: opt: 276 z-score: 329.4 E(): 5.6e-11; 24.7% FT identity in 267 aa overlap and to SW:PRXC_PSEFL FT (EMBL:AF031153) Pseudomonas fluorescens non-heme FT chloroperodixase (EC 1.11.1.10) (chloride peroxidase) FT (CPO-F) (chloropeorixidase F) Cpo or CpoF; fasta scores: FT opt: 233 z-score: 279.3 E():3.5e-08; 26.1% identity in 283 FT aa overlap. Contains Pfam match to entry PF00561 FT abhydrolase, alpha/beta hydrolase fold" FT /db_xref="HSSP:1EHY" FT /db_xref="InterPro:IPR000073" FT /db_xref="UniProtKB/TrEMBL:Q9RK83" FT /protein_id="CAB59583.1" FT /translation="MSAWPLPEAFTGGSGTVRWNRLGAPDGRPLVLLHGTPFSSYVWRA FT VARSLGRDHQVFVWDMPGYGVSEKSAGQDVSLAAQGRVFTELLEHWGLEEPLVAAHDFG FT GAVALRAHLLHGARYGALALVDPVALAPWGSPFFRLVRDHAEVFEQLPEALHRALVREY FT VGSTGGPGLHPAVLDRLVEPWLGETGQPAFYRQIAQADQRYTDEIQDRYTGIDVPTLIC FT WGEDDAWIPVAKGRELAGLVPGSRWEPIAHAGHLVQEDAPAELTAALLDFFRRVP" FT misc_feature 259041..259700 FT /note="Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold, score 62.30, E-value 1e-14" FT CDS complement(259812..260015) FT /transl_table=11 FT /gene="SCO0527" FT /gene_synonym="scoF" FT /gene_synonym="SCF11.07c" FT /product="cold shock protein" FT /note="SCF11.07c, scoF, cold shock protein, len: 67 aa. FT Identical to SW:CSPF_STRCO (EMBL:X92686) Streptomyces FT coelicolor cold shock protein ScoF and similar to FT SW:CSP7_STRCL (EMBL:X68245) Streptomyces clavuligerus cold FT shock-like protein 7.0, 66 aa; fasta scores: opt: 362 FT z-score: 493.9 E(): 3.8e-20; 74.6% identity in 67 aa FT overlap and to Streptomyces coelicolor SC10A5.26c, 67 aa; FT fasta scores: opt: 383 z-score: 518.2 E(): 1.5e-23; 82.1% FT identity in 67 aa overlap. Contains Pfam match to entry FT PF00313 CSD, 'Cold-shock' DNA-binding domain and Prosite FT match to entry PS00352 'Cold-shock' DNA-binding domain FT signature" FT /db_xref="GOA:P48859" FT /db_xref="HSSP:1CSP" FT /db_xref="InterPro:IPR012340" FT /db_xref="UniProtKB/Swiss-Prot:P48859" FT /protein_id="CAB59584.1" FT /translation="MASGTVKWFNSEKGFGFIAQDGGGPDVFAHYSNINAQGYRELQEG FT QAVTFDITQGQKGPQAENITPA" FT misc_feature complement(259821..259973) FT /note="Pfam match to entry PF00313 CSD, 'Cold-shock' FT DNA-binding domain, score 101.10, E-value 9.5e-27" FT misc_feature complement(259914..259973) FT /note="PS00352 'Cold-shock' DNA-binding domain signature" FT RBS 260336..260340 FT CDS 260346..261098 FT /transl_table=11 FT /gene="SCO0528" FT /gene_synonym="SCF11.08" FT /product="putative lipoprotein" FT /note="SCF11.08, possible lipoprotein, len: 261 aa; similar FT to various hypothetical proteins, e.g. TR:O07236 FT (EMBL:Z96800) Mycobacterium tuberculosis hypothetical 22.5 FT KD protein, 218 aa; fasta scores: opt: 157 z-score: 172.7 FT E(): 0.03; 25.3% identity in 194 aa overlap. Contains a FT Prosite match correctly situated to entry PS00013 FT Prokaryotic membrane lipoprotein lipid attachment site. FT Contains probable N-terminal signal sequence" FT /db_xref="InterPro:IPR005490" FT /db_xref="UniProtKB/TrEMBL:Q9RK82" FT /protein_id="CAB59585.1" FT /translation="MTVRKALALVIGAVMCTGVLATGCAREHAGASSQDAHAPGSSAAP FT RPAPPRSFPRPLPGVGPVMRDRLPDGTRQALVVTGETESSSQAQVVLYEQYPAEGWRAV FT AGPWPAHNGLRGWTDDHEAGDLHTPIGVFGLSDAGGRLPDPGTLLPYDEDPEFSVSGTG FT YLGEPLEGSFDYVVAIDYNRVPGTTPLDKARPLGEDKGGGVWIHVDHDGPTNACVSLSE FT EHMRALLTALDPDKEPVVVMGPREVLMR" FT misc_feature 260385..260417 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(261127..262545) FT /transl_table=11 FT /gene="SCO0529" FT /gene_synonym="SCF11.09c" FT /product="probable oxidoreductase (putative secreted FT protein)" FT /note="SCF11.09c, probable oxidoreductase (putative FT secreted protein), len: 508 aa; similar to TR:P75002 FT (EMBL:Z80356) Zymomonas mobilis glucose-fructose FT oxidoreductase precursor, 433 aa; fasta scores: opt: 270 FT z-score: 301.6 E(): 2e-09; 28.8% identity in 219 aa FT overlap. Contains a Pfam match to entry PF01408 FT GFO_IDH_MocA, oxidoreductase family. Contains possible FT n-terminal region signal sequence peptide" FT /db_xref="GOA:Q9RK81" FT /db_xref="InterPro:IPR017909" FT /db_xref="UniProtKB/Swiss-Prot:Q9RK81" FT /protein_id="CAB59586.1" FT /translation="MSQTPAVSRRLLLGSAAATGALATGIGSAAPVAAAEQAPRRRPGQ FT KSMIGVPFAAHPTVRVAVIGLGNRGGGMITGWAAVPGCTVTAVCDIRADRAERAADRLE FT SKGNPRPAEYGGSADSYARMLRRDDIDLVYIATPWEFHYEHGRAALLSGRHAVVELPVA FT TELRQLWDLVDTSERTRRHLLLSENCNYGRNELAMLKAAHDGLFGDLTNGHGGYLHDLR FT ELLFSDTYYTDSWRRLWHTRSTASFYPMHGLAPIAAAMDVNRGDRMTTLRATTTAPKGL FT ADYRARFVPRDHPSWKETYINGDLVTCMIETAKGRTVRAEHDVSSPRPYSRINTLAGSR FT GIVEDYAGSAPTGARIYVEPDHGGHTWRDFETYRKEYDHWLWQKVGDDAANNGGHGGMD FT YVLQWRTVQLMRAGLVPDIDVYDSAAWCSPVPLSVTSLARGGRPVEIPDFTRGAWRERR FT PGLDSAPTDMPPAG" FT misc_feature complement(261583..262371) FT /note="Pfam match to entry PF01408 GFO_IDH_MocA, FT Oxidoreductase family, score 18.10, E-value 9.1e-06" FT RBS complement(262556..262560) FT CDS complement(262731..263576) FT /transl_table=11 FT /gene="SCO0530" FT /gene_synonym="SCF11.10c" FT /product="putative transcriptional regulator" FT /note="SCF11.10c, possible transcriptional regulator, len: FT 281 aa; similar to SW:FARR_ECOLI (EMBL:X15790) Escherichia FT coli fatty acyl responsive regulator (P30 protein), 240 aa; FT fasta scores: opt: 286 z-score: 325.5 E(): 9.2e-11; 27.7% FT identity in 224 aa overlap. Contains Pfam match to entry FT PF00392 gntR, bacterial regulatory proteins, gntR family FT and Prosite match to entry PS00043 bacterial regulatory FT proteins, gntR family signature. Contains a possible FT helix-turn-helix motif between residues 36..57, score 1211 FT (+3.31 SD)" FT /db_xref="GOA:Q9RK80" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q9RK80" FT /protein_id="CAB59587.1" FT /translation="MEIDAAASGAVLKRERVRDAVLELIEDRRPGDAIPSERTLCAELG FT VSRPTLRAAIDELVVAGLLVREHGRGMFVAAEKITQELLSDRRAFSLPQAAGAWTSRLL FT EVRTLPAGARVGRKLRMSPAAQIHYVARLRLVDGSPMAIEYLHVPADLVSDLTSEELEQ FT GDLYEHLGERHDVRVSEAVQSIEPTVVTRAEADLLDVPELSPALLFERLTTDTRGRPVE FT YVHSLYRGDRYRIVSRLTLGPRDQAPPPGEGHHPGIPPGDFATKDPVTLSTRGVVQGGM FT " FT misc_feature complement(263355..263528) FT /note="Pfam match to entry PF00392 gntR, Bacterial FT regulatory proteins, gntR family, score 78.70, E-value FT 8.7e-23" FT misc_feature complement(263403..263477) FT /note="PS00043 Bacterial regulatory proteins, gntR family FT signature" FT misc_feature complement(263409..263474) FT /note="Helix-turn-helix from SCF11.10c between residues FT 36..57, score 1211 (+3.31 SD)" FT RBS complement(263583..263586) FT RBS 263793..263796 FT CDS 263803..265071 FT /transl_table=11 FT /gene="SCO0531" FT /gene_synonym="SCF11.11" FT /product="putative sugar transporter sugar binding protein" FT /note="SCF11.11, probable sugar transporter sugar binding FT protein, len: 422 aa; similar to TR:P72397 (EMBL:Y07706) FT Streptomyces coelicolor MalE, putative maltose-binding FT protein, 423 aa; fasta scores: opt: 367 z-score: 390.0 E(): FT 2.4e-14; 27.2% identity in 419 aa overlap. Contains Pfam FT match to entry PF01547 SBP_bacterial_1, bacterial FT extracellular solute-binding protein and a prosite match FT correctly situated to entry PS00013 prokaryotic membrane FT lipoprotein lipid attachment site. Contains probable FT N-terminal signal sequence" FT /db_xref="GOA:Q9RK79" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:Q9RK79" FT /protein_id="CAB59588.1" FT /translation="MKYRSLALLSTLVLGAGLAACSSSGGSADGAGDGRTALDVWLMRD FT SVSAQFQKEFETGFEKAHPEIDVKIQIQEWEGIGEKVTAALASNDAPDVIEVGNTQVAQ FT YAQSGGLTDFSGRVAELGGGDWLEGLAEPGAYDGRQYGIPYYAANRVVIHRTDLFEKAG FT IDPSRIRTRDQWIAATRKLNTGGTQGIYLPGQNWYVLSGFVWDEGGDLAVQSGGGWKGG FT LDSPGALRAMDFYRRLQALGKGPKDSDEAQPPQAEVMAKGQVAQIIAVPGGAKVIEEKN FT PELKGKLGFFPVPGKSADGPGAVFTGGSDLVVPAVAAHQEEAFTLIRELTGDAWQKKLA FT VAMSYVPNKTTLAGAVADDPGTAAMAAGAVNGHATPNTPQWAAVEAKNPIKEYMTAVLT FT GEDAGSAAAEASRTITETLGGDS" FT misc_feature 263833..263865 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature 264211..265050 FT /note="Pfam match to entry PF01547 SBP_bacterial_1, FT Bacterial extracellular solute-binding protein, score FT 62.00, E-value 1.2e-14" FT CDS 265141..266049 FT /transl_table=11 FT /gene="SCO0532" FT /gene_synonym="SCF11.12" FT /product="putative sugar transporter membrane protein" FT /note="SCF11.12, probable sugar transporter membrane FT protein, len: 302 aa; similar to TR:CAB55533 (EMBL:Y07706) FT Streptomyces coelicolor inner membrane protein MalF, 300 FT aa; fasta scores: opt: 493 z-score: 600.8 E(): 4.3e-26; FT 32.6% identity in 291 aa overlap. Contains a Pfam match to FT entry PF00528 BPD_transp, binding-protein-dependent FT transport systems inner membrane component and a prosite FT match to entry PS00402 binding-protein-dependent transport FT systems inner membrane component signature" FT /db_xref="GOA:Q9RK78" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9RK78" FT /protein_id="CAB59589.1" FT /translation="MPPGAAGRGTLWPYLLIAPAVLGMLYLLLYPLARAVLISFQDFRL FT RQLILGDADFVGLRNYRTLLGDPEFWEVVRRTFVFMAVGVVAIMVLSTLVALMTERLGR FT AARTVVLSSLVLVWAVPVVAATTVFQWLFHSEFGIVNETLTGLGFESYEGYPWFAHGGA FT AFGIVVVLIVWQSVPFAAITLYSALVTVPAELYESARMDGAGAARVFRSVTFPLIRPIF FT MLVLSLEVIWTFKAFVQIWVMTRGGPGEATTILPVYAVQTALAGQRYDLGSAASMLTVL FT LMSGVLVLYFRQLFRQEGEQP" FT misc_feature 265699..265932 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 55.40, E-value 1.3e-12" FT misc_feature 265702..265788 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS 266046..266903 FT /transl_table=11 FT /gene="SCO0533" FT /gene_synonym="SCF11.13" FT /product="putative sugar transporter membrane protein" FT /note="SCF11.13, possible sugar transporter membrane FT protein, len: 285 aa; similar to TR:CAB46387 FT (EMBL:AL096743) Streptomyces coelicolor putative integral FT membrane transport protein MalG, 296 aa; fasta scores: opt: FT 538 z-score: 675.0 E(): 3.2e-30; 33.7% identity in 279 aa FT overlap. Contains Pfam match to entry PF00528 BPD_transp, FT binding-protein-dependent transport systems inner membrane FT component and prosite match to entry PS00402 FT binding-protein-dependent transport systems inner membrane FT component signature" FT /db_xref="GOA:Q9RK77" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9RK77" FT /protein_id="CAB59590.1" FT /translation="MSTPRPRPPVRRALRRLPLNAAAALTVVVCLFPVYWMVTTAFKPS FT TDIQSYDPRLVPGAWTLEHFRKAVGADGFALFWRNSLLVTLSAVLLALLVALGAAYAVA FT RMRWRGRRQFMLAVFVAQMAPWESLIIPIYIISRDTGMLDRLPTLTLIYFMITLPFTVV FT VLRGFIAGIPPELEEAAQVDGCTRAGAFRRVAFPLLAPGLMATSLFGFITAWNEFTYAN FT FLIIKQQDSRTLPVWLSSFQSTFGTDWGATMAAATLFALPALVIFLALQRHVTAGLASG FT GVKG" FT misc_feature 266547..266774 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 55.20, E-value 1.4e-12" FT misc_feature 266550..266636 FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT RBS 266996..266999 FT CDS 267007..268626 FT /transl_table=11 FT /gene="SCO0534" FT /gene_synonym="SCF11.14" FT /product="putative beta-hexosaminidase (putative secreted FT protein)" FT /note="SCF11.14, possible beta-hexosaminidase (putative FT secreted protein), len: 539 aa; similar to TR:Q9ZH39 FT (EMBL:AF072374) Pseudoalteromonas sp. S9 FT beta-N-acetylglucosaminidase, 783 aa; fasta scores: opt: FT 1097 z-score: 1169.9 E(): 0; 36.6% identity in 527 aa FT overlap and SW:HEX1_VIBFU (EMBL:U41417) Vibrio furnissii FT beta-hexosaminidase (EC 3.2.1.52) FT (N-acetyl-beta-glucosaminidase) FT (beta-N-acetylhexosaminidase) ExoI: fasta scores: opt: 783 FT z-score: 836.7 E(): 0; 34.1% identity in 478 aa overlap. FT Contains Pfam match |