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EBI DbfetchID AL583924; SV 1; linear; genomic DNA; STD; PRO; 342300 BP. XX AC AL583924; XX DT 20-FEB-2001 (Rel. 66, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 4) XX DE Mycobacterium leprae strain TN complete genome; segment 8/10 XX KW . XX OS Mycobacterium leprae OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Corynebacterineae; Mycobacteriaceae; Mycobacterium. XX RN [1] RP 1-342300 RX DOI; 10.1038/35059006 RX PUBMED; 11234002. RA Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R., RA Wheeler P.R., Honore N., Ganier T., Churcher C., Harris D., Mungall K., RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K., RA Duthoy S., Feltwell T., Fraser A., Hamlin N., Holroyd S., Hornsby T., RA Jagels K., Lacroix C., Maclean J., Moule S., Murphy L., Oliver, Quail M.A., RA Rajandream M-A., Rutherford K.M., Rutter S., Seeger K., Simon S., RA Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Taylor K., RA Whitehead S., Woodward J.R., Barrell B.G.; RT "Massive gene decay in the leprosy bacillus"; RL Nature 409(6823):1007-1011(2001). XX RN [2] RP 1-342300 RA Parkhill J.; RT ; RL Submitted (20-FEB-2001) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Mycobacterium leprae sequencing teams, The RL Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, RL UK Unitie de Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du RL Docteur Rouux, 75724, Paris Cedex, France. E-mail: parkhill@sanger.ac.uk XX DR EMBL-CON; AL450380. DR RFAM; RF00005; tRNA. XX CC Notes: CC CC Details of M. leprae sequencing at the Sanger Centre CC are available from http://www.sanger.ac.uk/Projects/M_leprae/ CC A relational datbase containing the M. leprae sequences is available from CC http://genolist.pasteur.fr/Leproma/ XX FH Key Location/Qualifiers FH FT source 1..342300 FT /organism="Mycobacterium leprae" FT /strain="TN" FT /mol_type="genomic DNA" FT /db_xref="taxon:1769" FT CDS 275..430 FT /pseudo FT /transl_table=11 FT /gene="ML1963" FT /product="probable neuraminidase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3463 (Best blastx score 121)" FT CDS 483..1484 FT /transl_table=11 FT /gene="rmlB" FT /gene_synonym="ML1964" FT /product="dTDP-glucose 4,6-dehydratase" FT /note="Similar to M. tuberculosis dTDP-glucose FT 4,6-dehydratase rmlB Rv3464 TR:O06329 (EMBL:Z95390) (331 FT aa); Fasta score E(): 0, 84.0% identity in 331 aa overlap, FT and TR:Q50556 (EMBL:U43540) (329 aa); Fasta score E(): 0, FT 78.2% identity in 331 aa overlap, and to others e.g. FT Streptococcus pneumoniae DTDP-glucose-4,6-dehydratase cpsN FT TR:O54611 (EMBL:AF030364) (349 aa); Fasta score E(): 0, FT 59.9% identity in 334 aa overlap. Contains Pfam match to FT entry PF01370 Epimerase, NAD dependent FT epimerase/dehydratase family." FT /note="Similar to ML0204, ML0751, ML1942 and ML2428" FT /db_xref="GOA:Q9CBH7" FT /db_xref="HSSP:1KEP" FT /db_xref="InterPro:IPR001509" FT /db_xref="InterPro:IPR005888" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9CBH7" FT /protein_id="CAC30919.1" FT /translation="MTMRLLVTGGAGFIGANFVHNAVRDHPDDTVTVLDAMTYAGRHES FT LADVDHAVRLVQGNITDTKLVFRLVAESDVVVHFAAETHVDNALDDPEPFLRTNVIGTF FT TILEAVRHHSVRLHHISTDEVYGDLELDEPTRFTESTPYNPSSPYSATKAAGDMLVRAW FT VRSYGVRATISNCSNNYGPYQHVEKFIPRQITNVLTGRRPKLYGTGVNVRDWIHVDDHN FT SAVWQILEKGQIGRTYLIGAENGHNNLTVLRTLLQMMGRDPNDFDHVTDRVGHDLRYAI FT DPTPLYNELCWAPKHANFDEGLRATIDWYRNNESWWRPLKDAVEARYEERGR" FT misc_feature 495..1424 FT /note="Pfam match to entry PF01370 Epimerase, NAD dependent FT epimerase/dehydratase family, score 470.30, E-value FT 1.6e-137" FT CDS 1486..2094 FT /transl_table=11 FT /gene="rmlC" FT /gene_synonym="ML1965" FT /product="dTDP-4-dehydrorhamnose 3,5-epimerase" FT /note="Similar to M. tuberculosis dTDP-4-dehydrorhamnose FT 3,5-epimerase rmlC Rv3465 TR:O06330 (EMBL:Z95390) (202 aa); FT Fasta score E(): 0, 75.4% identity in 199 aa overlap, and FT to many others e.g. Streptomyces griseus FT DTDP-4-dehydrorhamnose 3,5-epimerase SW:STRM_STRGR (P29783) FT (200 aa); Fasta score E(): 0, 45.6% identity in 193 aa FT overlap. Contains Pfam match to entry PF00908 FT dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase." FT /db_xref="GOA:Q9X7A4" FT /db_xref="HSSP:1EP0" FT /db_xref="InterPro:IPR000888" FT /db_xref="InterPro:IPR011051" FT /db_xref="InterPro:IPR014710" FT /db_xref="UniProtKB/TrEMBL:Q9X7A4" FT /protein_id="CAC30920.1" FT /translation="MNVKELDISGAWEITPTIHSDSRGMFFEWLTASRFSAFTGHRLDV FT RQANCSVSSAGVLRGLHFAQVPPSQAKYVTCVTGSVFDVVVDIRLGSPTFGCWTSITLN FT DSNRKTIYISESLAHGFLALQDNSTVMYLCSAEYNPAREHAICATDPDLAIDWPVVDGV FT DTHLSKRDATAPNLDDIRASGLLPTWDETQNFIANLGSK" FT misc_feature 1492..2025 FT /note="Pfam match to entry PF00908 dTDP_sugar_isom, FT dTDP-4-dehydrorhamnose 3,5-epimerase, score 308.80, E-value FT 6.5e-89" FT CDS 2139..2624 FT /transl_table=11 FT /gene="lpqH" FT /gene_synonym="ML1966" FT /product="possible lipoprotein" FT /note="Similar to M. tuberculosis 19 kDa lipoprotein FT antigen precursor lpqH Rv3763. Contains a possible FT N-terminal signal sequence and a PS00013 Prokaryotic FT membrane lipoprotein lipid attachment site." FT /db_xref="GOA:Q9X7A5" FT /db_xref="InterPro:IPR008691" FT /db_xref="UniProtKB/TrEMBL:Q9X7A5" FT /protein_id="CAC30921.1" FT /translation="MRHKLLAAIYAVTIMAGAAGCSGGTQAPTPSVSKTTNSSPTTVAS FT SIPDAAAGETKVTIGGQPQKVSGPVVCSTTNGKFSIAIGDMITGVIVGLEPDASVVHNA FT GLGTIDGVVIAFTEGVPSENANATKNGNTYQITGTASGVDNTGQQIHKSFEIEVTCR" FT misc_feature 2169..2201 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(4768..4995) FT /pseudo FT /transl_table=11 FT /gene="ML1967" FT /product="PPE family protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog PPE" FT CDS complement(5464..5649) FT /pseudo FT /transl_table=11 FT /gene="ML1968" FT /product="PE family protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog PE" FT repeat_region complement(5661..8043) FT /note="Dispersed repeat, LEPREP, copy 6 " FT CDS complement(5848..5946) FT /pseudo FT /transl_table=11 FT /gene="ML1969" FT /note="Similar to Agrobacterium tumefaciens transposase FT TR:Q44454 (EMBL:Z18270) (366 aa) fasta scores: E(): 0.0002, FT 51.5% id in 33 aa, and to Pseudomonas putida transposase FT tnpa1 TR:Q9R9U9 (EMBL:AJ245436) (355 aa) fasta scores: E(): FT 0.00088, 48.5% id in 33 aa" FT CDS complement(6211..7354) FT /pseudo FT /transl_table=11 FT /gene="ML1970" FT /product="putative group II intron maturase-related FT protein" FT /note="Similar to many e.g. Cryphonectria parasitica FT (Chesnut blight fungus) putative maturase TR:AAF27656 FT (EMBL:AF218567) (778 aa) fasta scores: E(): 7.8e-11, 29.2% FT id in 216 aa" FT stem_loop complement(6674..6727) FT CDS complement(7559..7698) FT /pseudo FT /transl_table=11 FT /gene="ML1971" FT /note="Similar to Pseudomonas putida transposase tnpa1 FT TR:Q9R9U9 (EMBL:AJ245436) (355 aa) fasta scores: E(): FT 3.4e-05, 47.8% id in 46 aa, and to Agrobacterium FT tumefaciens transposase TR:Q44454 (EMBL:Z18270) (366 aa) FT fasta scores: E(): 0.00026, 41.3% id in 46 aa" FT repeat_region complement(8044..8189) FT /note="146 bp sequence found at 5'-end of copies 6 and 7 of FT LEPREP" FT CDS complement(8461..8691) FT /transl_table=11 FT /gene="ML1972" FT /product="hypothetical protein" FT /note="unknown." FT /db_xref="UniProtKB/TrEMBL:Q9CBH6" FT /protein_id="CAC30927.1" FT /translation="MPSRNRDANVVDLTDSHSREAFFNEALGGATKVLVMITEGLVMYL FT DDRDVILLSEVITRSEVTWWVLDLAGPGLKK" FT CDS 9727..10530 FT /pseudo FT /transl_table=11 FT /gene="ML1973" FT /product="glycosyl hydrolase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv0315 (Best blastx score 130)" FT CDS 10602..12320 FT /transl_table=11 FT /gene="ML1974" FT /product="unknown permease" FT /note="Similar to M. tuberculosis probable permease Rv1979c FT SW:YJ79_MYCTU (Q10875) (481 aa); Fasta score E(): 0, 76.8% FT identity in 462 aa overlap, and to e.g. Arabidopsis FT thaliana putative amino acid transporter TR:Q9SQZ0 FT (EMBL:AC011560) (584 aa); Fasta score E(): 2.1e-13, 23.0% FT identity in 508 aa overlap. Contains Pfam match to entry FT PF00324 aa_permeases, Amino acid permease. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop)." FT /note="Similar to ML1304 and ML1305" FT /db_xref="GOA:Q9CBH5" FT /db_xref="InterPro:IPR002293" FT /db_xref="InterPro:IPR004841" FT /db_xref="UniProtKB/TrEMBL:Q9CBH5" FT /protein_id="CAC30929.1" FT /translation="MFLSADVSCIEIVDINCSELRNDRRIPPQLALFCTNAANKAESAV FT TSHGQLPIMANRRWAPHTRRQSGRATSTCSSLMRFSASESRAHSRFECYTLVRWSIRGQ FT GGRAISKLGFWSVVMLGINSIIGAGIFMTPGEVIKIAGPFAPIAYTLAGIFAAVLAIVF FT ATAAKYVKTNGSSYAYTTAAFGHRIGIYVGVTHAITASIAWGVLASSFVSTLLRVAFPE FT KIWADNDELISVKTLTFLVFIAVLLAINIFGNLVIRWANGISALGKIFALSVFIAGGLW FT TIITQHVNNYVTSRSAYQPTTYSLLGVTEIGKSTAASMTLATIVALYAFTGFESIANAA FT EEMNTPDRTLPKAIPLTILTVGVIYILALVVAMLLGSDKIVATNHTVKLAAAVGNNTFR FT TIIVVGALVSMFGINVAASFGAPRLWTALSDGRILPTRLSSKNRFGVPIVAFGITAFLT FT LAFPLSLRFDSLNLTGLAVIARFIQFIIVPIALFALARSRTTNSVYVKRNVFTDKVLPI FT TAVVVSAGLMVSFDYRSIFLTRGGPNYFSISLIAITFIGIPAVAYLHYYRTSGIK" FT misc_feature 10932..12302 FT /note="Pfam match to entry PF00324 aa_permeases, Amino acid FT permease, score -176.40, E-value 4.2e-06" FT misc_feature 11520..11543 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 12942..13199 FT /pseudo FT /transl_table=11 FT /gene="ML1975" FT /product="probable oxidoreductase (pseudogene)" FT CDS complement(13369..13716) FT /transl_table=11 FT /gene="ML1976" FT /product="very hypothetical protein" FT /note="unknown; questionable CDS." FT /db_xref="UniProtKB/TrEMBL:Q9CBH4" FT /protein_id="CAC30931.1" FT /translation="MIMPKSIIPQERCRHHLNLFRRQNCYFNRFDHKNSIARHERLRIA FT LAPLATTKPAIRPEISDASIASRLIYRVYRGAGLLRSIARKTVLALRLGMPMLGRGEET FT LSANIPTSKSR" FT CDS 13984..14561 FT /pseudo FT /transl_table=11 FT /gene="ML1977" FT /product="membrane protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2025c (Best blastx score 209)" FT CDS 14591..15226 FT /pseudo FT /transl_table=11 FT /gene="ephF" FT /gene_synonym="ML1978" FT /product="probable epoxide hydrolase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog ephF FT (Best blastx score 78)" FT CDS complement(16084..16491) FT /transl_table=11 FT /gene="ML1979" FT /product="hypothetical protein" FT /note="unknonwn." FT /db_xref="UniProtKB/TrEMBL:Q9CBH3" FT /protein_id="CAC30934.1" FT /translation="MTVTGFFVLGLFAVVVVVLTLGDYDDTSHDVELALACVLWPIELS FT GAMSVPSADGAALVTAGAVVPVVSRQLGCRPIGSSSVSCVPEPNSFARIIYASVLAPDL FT FDKIIRDRMGRHAERQSICCGVVNLRNTCAR" FT CDS complement(17249..18045) FT /pseudo FT /transl_table=11 FT /gene="fadD31" FT /gene_synonym="ML1980" FT /product="acyl-CoA synthase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT fadD31 (Best blastx score 214)" FT CDS 18241..18610 FT /pseudo FT /transl_table=11 FT /gene="ML1981" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1924c (Best blastx score 169)" FT CDS 18747..19055 FT /transl_table=11 FT /gene="ML1982" FT /product="putative integral membrane protein" FT /note="Some similarity to transport proteins e.g. FT Escherichia coli short-chain fatty acids transporter FT SW:ATOE_ECOLI (P76460) (440 aa); Fasta score E(): 0.064, FT 32.7% identity in 55 aa overlap." FT /db_xref="GOA:Q9CBH2" FT /db_xref="InterPro:IPR006160" FT /db_xref="UniProtKB/TrEMBL:Q9CBH2" FT /protein_id="CAC30937.1" FT /translation="MSHLTRLCVRYVKRFMPDPYLFAAILTIIVVMLTAPLVRDTTAAS FT MFKARYSGVWGSQHIFHLHVTDGAGPSDWATRWPRLPVLSSAIVHIGVNLRIRCKAL" FT CDS 19568..20035 FT /transl_table=11 FT /gene="ML1983" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis gene with weak similarity FT to pollen antigens Rv1919c TR:O53961 (EMBL:AL022020) (154 FT aa); Fasta score E(): 0, 72.8% identity in 151 aa overlap." FT /db_xref="InterPro:IPR019587" FT /db_xref="UniProtKB/TrEMBL:Q9CBH1" FT /protein_id="CAC30938.1" FT /translation="MSNRKFSFEVTRTSSASAAVLFRLVTDGANWAKWAKPIVLQSSWA FT RLGDLRPGGIGAVRKIGIWPILVREETVEYEQDRRHLYKLIGPPNPAKDYLGEVLLAPN FT AAGGTNIHWSGSFTENIPGTGPVMRAALKGAVRCLTVRLVKTAERESDGVQ" FT CDS complement(20257..21285) FT /pseudo FT /transl_table=11 FT /gene="ML1984" FT /product="possible oxidoreductase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv3618 (Best blastx score 108)" FT CDS complement(21952..24348) FT /transl_table=11 FT /gene="aceA" FT /gene_synonym="ML1985" FT /product="isocitrate lyase" FT /note="Previously sequenced as Mycobacterium leprae FT isocitrate lyase SW:ACEA_MYCLE (P46831) (606 aa); Fasta FT score E(): 0, 99.8% identity in 568 aa overlap. Similar to FT M. tuberculosis isocitrate lyase N-terminal and C-terminal FT modules aceAa Rv1915 TR:O07718 (EMBL:Z97193) (367 aa); FT Fasta score E(): 0, 87.1% identity in 295 aa overlap and FT aceAb Rv1916 TR:O07717 (EMBL:Z97193) (398 aa); Fasta score FT E(): 0, 87.9% identity in 397 aa overlap, and to many FT others e.g. Coprinus cinereus isocitrate lyase FT SW:ACEA_COPCI (O13439) (537 aa); Fasta score E(): 0, 38.1% FT identity in 586 aa overlap. Contains 2 Pfam matches to FT entry PF00463 ICL, Isocitrate lyase. Contains PS00161 FT Isocitrate lyase signature." FT /db_xref="GOA:P46831" FT /db_xref="InterPro:IPR000918" FT /db_xref="InterPro:IPR006254" FT /db_xref="InterPro:IPR015813" FT /db_xref="InterPro:IPR018523" FT /db_xref="UniProtKB/Swiss-Prot:P46831" FT /protein_id="CAC30940.1" FT /translation="MAGIPATVVQRCNSTNLDDRLHYSPLGDRAKEERNPMAIMDTNTE FT VHTLFTQEVAATQQYFDDPRFAGIIRLYTARQVVEQRGTIPTDYTVARDAATAFYARLR FT ELFAAGKSVTTFGPYSPGQAVSLKRMGIEAIYLGGWATSAKGSITEDPGPDLASYPLSQ FT VPDDAAVLVRALLAADRNQQYLRLHMTEQQRAATPAYDYRPFIIADADTGHGGDSHVRN FT LIRRFVEIGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGII FT VARTDAEAANLIDSRADERDQPFLLGATNLKIPSYKACFLALVRCFYELGVKELHGHLL FT YALGDGEYAAASAWLDRQGILAQVSGTVNAWQENGKQSIDDLFEQVEYRLLAAWEKDAG FT LMTYGEAVEEMLQFGESEGELIGMSPEEWRRFVGRASLYAAREKAKELGVDPGWDCELA FT KTPEGYYQIRGGIQYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPEQMLA FT YNLSPSFNWDTTGMSDEEMKRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDG FT MLALARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQ FT TEVPKKLLEEWLALWSEHYQLGEKLRVQLRPRRAGSDVLELGIYGNGDEQLANVIVDPI FT KDRRGRSILQVRDQNTFAEKLRQKRLMTLIHFWLVHRFKADTVIYVTPTEDNLYQTSKM FT KSHGIFSEVYQEVGEIIVAEVNHPRLVELLTPDRVALRRLITKEG" FT misc_feature complement(22612..23031) FT /note="Pfam match to entry PF00463 ICL, Isocitrate lyase, FT score 171.30, E-value 1.8e-67" FT misc_feature complement(23419..24192) FT /note="Pfam match to entry PF00463 ICL, Isocitrate lyase, FT score 282.60, E-value 4.1e-111" FT misc_feature complement(23599..23616) FT /note="PS00161 Isocitrate lyase signature" FT CDS complement(24890..25341) FT /pseudo FT /transl_table=11 FT /gene="ML1986" FT /product="ECF subfamily sigma subunit (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog sigC FT (Best blastx score 104)" FT CDS 25577..27877 FT /transl_table=11 FT /gene="ctpA" FT /gene_synonym="ML1987" FT /product="putative cation-transporting ATPase" FT /note="Similar to Mycobacterium tuberculosis FT cation-transporting P-type ATPase A ctpA or Rv0092 or FT MTCY251.11 SW:CTPA_MYCTU (Q10876) (761 aa) fasta scores: FT E(): 0, 77.2% id in 715 aa. Previously sequenced as FT SW:CTPA_MYCLE (P46839). Contains multiple possible membrane FT spanning hydrophobic domains and Pfam match to entry FT PF00122 E1-E2_ATPase, E1-E2 ATPase. Contains PS00154 E1-E2 FT ATPases phosphorylation site." FT /note="Similar to ML0747 and ML2000" FT /db_xref="GOA:P46839" FT /db_xref="InterPro:IPR000579" FT /db_xref="InterPro:IPR001757" FT /db_xref="InterPro:IPR005834" FT /db_xref="InterPro:IPR006121" FT /db_xref="InterPro:IPR006403" FT /db_xref="InterPro:IPR006416" FT /db_xref="InterPro:IPR008250" FT /db_xref="InterPro:IPR017969" FT /db_xref="InterPro:IPR018303" FT /db_xref="UniProtKB/Swiss-Prot:P46839" FT /protein_id="CAC30942.1" FT /translation="MRAPNGWNNLPNKLSDFSTLVNSATRVAAINLSEVTQTAEVCEAV FT RRAALCTDGGEALQRRQADADNARYLLIRLAVAAALFVPLAHLSVMFAVLPSTHFPGWE FT WMLTALAIPVVTWAAWPFHRVAIHNARYHGASMETLISTGITAATIWSLYTVFGHHQST FT EHRGVWRALLGSDAIYFEVAAGITVFVLAGKYYTARAKSHASIALLALAALSAKDAAVL FT QPDGSEMVIPANELNEQQRFVVRPGQTIAADGLVIDGSATVSMSPITGEAKPVRVNPGA FT QVIGGTVVLNGRLIVEAAAVGDETQLAGMVRLVEQAQQQNANAQRLADRIASVFVPCVF FT AVAALTAVGWLIAGSGPDRVFSAAIAVLVIACPCALGLATPTAMMVASGRGAQLGILLK FT GHESFEATRAVDTVVFDKTGTLTTGQLKVSAVTAAPGWQANEVLQMAATVESASEHAVA FT LAIAASTTHREPVANFRAVPGHGVSGTVAERAVRVGKPSWIASRCNSTTLVTARRNAEL FT RGETAVFVEIDGEQCGVIAVADAVKASAADAVAALHDRGFRTALLTGDNPASAAAVASR FT IGIDEVIADILPEDKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVAI FT GAADIILVRDNLDVVPITLDLAAATMRTIKFNMVWAFGYNIAAIPIAAAGLLNPLVAGA FT AMAFSSFFVVSNSLRLRNFGAILSCGTSRHRTVKRWRCPPPTRLRSTACSPVDASPLRP FT VAHRTGVKPPTHR" FT misc_feature 26129..27697 FT /note="Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 FT ATPase, score 763.50, E-value 8.9e-226" FT misc_feature 26822..26842 FT /note="PS00154 E1-E2 ATPases phosphorylation site" FT CDS complement(27855..28568) FT /transl_table=11 FT /gene="ML1988" FT /product="probable integral membrane protein" FT /note="Similar to M. tuberculosis probable integral FT membrane protein Rv0093c SW:Y093_MYCTU (Q10890) E():0 70.3% FT id in 236 aa. Contains possible membrane spanning FT hydrophobic domains. Note lacks the N-terminal 46 aa of the FT M. tuberculosis protein." FT /db_xref="UniProtKB/TrEMBL:Q9CBG8" FT /protein_id="CAC30943.1" FT /translation="MDCEVAREALSARLDGEREAVPSVRVDEHLGECSACRAWFDQVAD FT QARDLRQLVDSRPAITPVDALGIVAPPRRRRPLMTWQRWALLCVGIAQIVLATVQGLGV FT SVGLTHDRAMSFGSYLLHESTAWSASLGVIMMAAVLWPGVAAGLAGVLTVFVGLLTVYV FT VVDVVAGATITLRILMHLPVAIGAVLAIAVWRHSSTPRPTFDDEVDVDLDIVLPRNASR FT GRRRGHLWPTDGSAV" FT CDS complement(28885..29235) FT /transl_table=11 FT /gene="ML1989" FT /product="hypothetical protein" FT /note="unknown." FT /db_xref="UniProtKB/TrEMBL:Q9CBG7" FT /protein_id="CAC30944.1" FT /translation="MARFGDCLFGDRLSGSMAIWRAIAPDVYLHRTVVAIRDCILILFR FT YAGHQNEAAIRAADGNLLLQQMVRLALVWSAKTTSNSPSDDLLHSNPQPEIYSTKSTNY FT VNLSTIGIKLKI" FT CDS complement(29315..29557) FT /transl_table=11 FT /gene="ML1990" FT /product="putative integral membrane protein" FT /note="no database matches. Contains possible membrane FT spanning hydrophobic domains." FT /db_xref="UniProtKB/TrEMBL:Q9CBG6" FT /protein_id="CAC30945.1" FT /translation="MFSVMLFILCIREIYRNPTAITVSMTVIAVGFLAQAAAVSIATNV FT VATGRHNTINFNVDTVGFVNAWSLLFYPPQGWESP" FT CDS 30644..32050 FT /transl_table=11 FT /gene="PPE" FT /gene_synonym="ML1991" FT /product="PPE-family protein" FT /note="Similar to M. tuberculosis PPE-family protein Rv0096 FT SW:Y096_MYCTU (Q10892) (463 aa); Fasta score E(): 0, 58.6% FT identity in 466 aa overlap. Contains Pfam match to entry FT PF00823 PPE, PPE family." FT /note="Similar to ML1828 and ML0539" FT /db_xref="InterPro:IPR000030" FT /db_xref="UniProtKB/TrEMBL:Q9CBG5" FT /protein_id="CAC30946.1" FT /translation="MAIPPEVHSVLLSAGQGAESLLVAATQWQELSKQYTYAAAELTRL FT LTHVQATSWRGTSATRFVAAHGAYLVWLEQTSINNAITAKQHEIAAIAYSSALAAMPTL FT AELTANRATRGFLIATNFFGINTIPIALNEADYVRMWVQAADTMATYQAISEAVTATIL FT PTQVAPPILAPGSATQNVLQSVPDWIVQLLTDILDFIADPYKYFLRFFQRLGFRPAIAV FT VLAIIALQLYDFLWYPYYASYGMLLLPFFAPALSVLGTLSVLWNGQLSAGLPPNPAGSH FT PDNNAGPRIHVGVAPPASATSSGNSYTSNSAPSTSASATTDNPLSSPSIRYAIPGLSPP FT EVSSGPKAGTKSPDTATNTIGITAAARTNSPSARAHRKRGNKTRGGARGYRYEFVEGTA FT TMADTVDAPDHSEPTSHTISNHSAGPIGFAGTVPTTASTPTGMAASTSSSVPLLPTTWI FT TGTSETAVHE" FT misc_feature 30647..31123 FT /note="Pfam match to entry PF00823 PPE, PPE family, score FT 309.10, E-value 5.4e-89" FT CDS 32199..33068 FT /transl_table=11 FT /gene="ML1992" FT /product="putative oxidoreductase" FT /note="Similar to M. tuberculosis hypothetical protein FT Rv0097 SW:Y097_MYCTU (Q10893) (289 aa); Fasta score E(): 0, FT 76.4% identity in 288 aa overlap, and to Escherichia coli FT alpha-ketoglutarate-dependent taurine dioxygenase FT SW:TAUD_ECOLI (P37610) (282 aa); Fasta score E(): 2.6e-10, FT 24.5% identity in 278 aa overlap." FT /db_xref="GOA:Q9CBG4" FT /db_xref="InterPro:IPR003819" FT /db_xref="UniProtKB/TrEMBL:Q9CBG4" FT /protein_id="CAC30947.1" FT /translation="MTLDVKGDGLGAQVTGVDPKNLDSISTAEIRKIVYVNKLVVLKDV FT HPTPEEFIKLGRIIGEIVPYYEPIYRHKDYPEIFVSSTEEGQGVPNTGAFWHVDYIFMP FT EPFAFSMTLPLAMPGHDRGTHFIDLSQVWESLPNAMKDSVRGTYSNHSPRRYIKIRPSD FT VYRPVGEVLAEIEEVTPPQKWPTVIKHPKTGQEILYICEAATVSVEDKNGNLLDPMVLQ FT ELLTASGQLDPDCKSLLIHTQHYEVGDVVLWDNRALVHRAKHGTVSGTLITYRLTLLDG FT LKTPGYAV" FT CDS 33065..33616 FT /transl_table=11 FT /gene="ML1993" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis hypothetiacl protein FT RV0098 SW:Y098_MYCTU (Q10894) (183 aa); Fasta score E(): 0, FT 65.6% identity in 180 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9CBG3" FT /protein_id="CAC30948.1" FT /translation="MSAELAPSLQNAAESTNTFPMAEDLLGSILEPYSYKGCRYLIDAQ FT YRASPDSVFAYGNFGIEESAYIRGTGHFNAVELMLCFNQLGYSAYAQSVVNKDISALRG FT WSIADYCRNQLSGILIKNTSSRFKKLINPQKFSARLHVYDLRIVERTWRYLQLSNTIEF FT WDDNGGSAIGEFEVAILNIP" FT RBS 33626..33630 FT /note="possible RBS" FT CDS 33646..35244 FT /transl_table=11 FT /gene="fadD10" FT /gene_synonym="ML1994" FT /product="acyl-CoA synthase" FT /note="Similar to Mycobacterium tuberculosis putative FT acyl-CoA synthases e.g. Rv0099 or MTCY251.18 TR:Q10878 FT (EMBL:Z74410) (540 aa) fasta scores: E(): 0, 74.6% id in FT 531 aa. Previously sequenced as TR:Q50176 (EMBL:Z46257). FT Contains Pfam match to entry PF00501 AMP-binding, FT AMP-binding enzyme. Contains PS00455 Putative AMP-binding FT domain signature." FT /db_xref="GOA:Q50176" FT /db_xref="HSSP:1LCI" FT /db_xref="InterPro:IPR000873" FT /db_xref="InterPro:IPR020845" FT /db_xref="UniProtKB/TrEMBL:Q50176" FT /protein_id="CAC30949.1" FT /translation="MSHLPPTVLERILKQAHERPEAIALRRSDGTSELRYGQLVAEVNG FT LAAHLSAQSVSQRSRVLVISDNGPETYLSVLACAKLGAIAVMVDGNLPPATISRFSEIC FT DPSAVLVARECRIDSSSLPEILHSIPAITVNTTADATYSACSLDIDYLAGNLNYGTDDP FT LAMTFTSGTTGEPKAVLLPNRTFFAIPDILREKGLAWIDWVVNETTYSPLSATHIGGLW FT WILNCLMHGGLCITGGEHTSSLTEVLNANKVATTCLVPTLLSKLVYELKFGDVVTPPLR FT LIVYGGSRVIAADVRFIEAAGVRTAQFYGLSETGCTALCLPTDNGSISKIEAGAVGRPY FT PGVEVYLADPNGGGPTVADTASSASFGTLWIKSPANMLGYWNNPERTREILVDGWVNTG FT DLVERREDGFFYIKGRSSEMIVSGGVNIVPDEVDRIAESVSGVGEAACYEIPDAHFGAL FT VGLAVIPSAELNESTAIELKRRIAARYRRESESMARPSKIVIVADIPRTQSGKVIRATL FT AAALNGEQLGMVVRD" FT misc_feature 33751..34986 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 41.30, E-value 1e-17" FT misc_feature 34141..34176 FT /note="PS00455 Putative AMP-binding domain signature" FT CDS 35237..35473 FT /transl_table=11 FT /gene="ML1995" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis hypothetical protein FT Rv0100 SW:Y100_MYCTU (Q10895) (78 aa); Fasta score E(): FT 1.1e-18, 69.0% identity in 71 aa overlap. Contains Pfam FT match to entry PF00550 pp-binding, Phosphopantetheine FT attachment site." FT /db_xref="GOA:Q9CBG2" FT /db_xref="InterPro:IPR006163" FT /db_xref="UniProtKB/TrEMBL:Q9CBG2" FT /protein_id="CAC30950.1" FT /translation="MTETARERILTAVCEVLYIAESDLVDGDETDLRDLGLDSVRFTLL FT MKQLGLSQEAEMQSKLMDNFSIANWVRQLESST" FT misc_feature 35255..35383 FT /note="Pfam match to entry PF00550 pp-binding, FT Phosphopantetheine attachment site, score 25.60, E-value FT 1.9e-05" FT CDS 35470..39675 FT /transl_table=11 FT /gene="nrp" FT /gene_synonym="ML1996" FT /product="probable peptide synthase" FT /note="Similar in N-terminus to M. tuberculosis probable FT peptide synthetase nrp Rv0101 TR:Q10896 (EMBL:Z74410) (2512 FT aa); Fasta score E(): 0, 65.7% identity in 1089 aa overlap, FT and to e.g. Streptomyces sp streptothricin peptide synthase FT TR:O33743 (EMBL:Y10293) (481 aa); Fasta score E(): 5.6e-20, FT 31.2% identity in 382 aa overlap. Contains Pfam match to FT entry PF00501 AMP-binding, AMP-binding enzyme. Contains FT PS00455 Putative AMP-binding domain signature. Contains FT PS00017 ATP/GTP-binding site motif A (P-loop)." FT /note="Similar to ML1051 and ML0243" FT /db_xref="GOA:Q50177" FT /db_xref="InterPro:IPR000873" FT /db_xref="InterPro:IPR010080" FT /db_xref="InterPro:IPR013120" FT /db_xref="InterPro:IPR016040" FT /db_xref="InterPro:IPR020845" FT /db_xref="UniProtKB/TrEMBL:Q50177" FT /protein_id="CAC30951.1" FT /translation="MTAPNTRRVDRVPLSRSQQNIYNGMLQDNDPALYFIGKSYRFHQL FT ELSVFLAALEATILKNPGQLCVLEAPSTEGDYPDLVPRLQFGDIVRVRSDEQPQTDSRD FT YDLMHAWSPDILAKPLVRYTVRTDKNGFVARLDVFTHHILVDGGAIRIIEENLAHHLDT FT DNRLEIPCIRQALDKLAEAHRREATKVEESLQRLANVVQRELADEVRNGGYGQVSNDAP FT GNAARGVLHESMIICGKAFDNIIALSETKQVPLNILVATAAVAVDASLRQSTEGLLVHA FT VDNRFGDPYLDVATCLVNSVAHSIRFPPFASVQDVVRTLDRSYVKAIRLRWLREEYYRR FT IYLALNQTSHIEALTLNFIREPCAPGLRPFLSEVPTVTDIGPVEGMTVACVLNEDERTL FT DLSIWNRVDLPQGKSCTRVAKRIAAALELMAAAWDQPIAMIVNEWFGISSDGALCLGNE FT VTQTTRPLAPAWFLDPGGSVHLTVDKRRYVHPWIAWLVRGSVVPGDVLVFTDDNTDKTI FT DLLIACHLAGCGYSVCDTVAEVPLRAKAITDHGGGVSARVIDVAATQLAVTPDNEQSKL FT ADKLIKQAAQDISLADKTAYIMPTSGSTGQPKLVQVSHGSLALFCDAVRNAYGWGAHDT FT ILQCAPLTSDISVEEIFGGAICGSKLVRSTAMKTGDLAELARDIFVQRATVIDLPTAVW FT HLLCDHSDAIDEINRSCLRQIVIGGEAVRPCAVDKWIDSGASQGISLMSTYGPTETTVV FT VTYLPIVCAPMTVESDARLRLGWPIVPNTVFIAFGELVIVGDLVSVGYLGIDSRNFGTV FT TTTDGSCRRAFATADCVILDDEGFPVFSGRKDAVVKISGKRVDTAELIRRISTDPNVSD FT VAVEVYNGRLGVWFETKLTREGVDDAAAATRSRLILASLGVSSFFVVGVPCIPRKPNGK FT IDRDNLLVMPQLVDSVQNYAGSGEGAAGLAEIWSRHLGRAILPDSSLLDEGIGSVDLIR FT ILPDTRRHLGRHLSLLDLISADNAANLTAAQTANVWMDVGTAAEIERDLASLCRQRNAT FT EFSVKQTRNSHQKQAIVVLGASGILGTGFAQAVLDLRQSGVLCPEVVLATRARLPEGDP FT WTALQGVDGVRIERISFENGPGELEALIRDTDAGTLVNGVGNTNMLVPYRELRLANVEL FT VSAIVDICASYSTRLVHLSSFVVNADVTVPQVTDPRETPYPYAASKSLAELVVAGSPSA FT LDFTIVRLPRVLGEDYQLRNSSDILLSIVDACIALRAYPSATVTEEVTTGRAAAKAILG FT VVSALARSGQLGSGISVVRGEAVAYADFLSEFASDELNMAEWKYRLDQSDWAKRNPRRW FT SVIDAWFTLGMMFEMRSYAEYPTMALGVESVAELAAPPESIRALLAHGCSQPLKYTGR" FT misc_feature 35563..35586 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 36922..38091 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score 14.50, E-value 3.2e-16" FT misc_feature 37258..37293 FT /note="PS00455 Putative AMP-binding domain signature" FT CDS complement(39682..40314) FT /transl_table=11 FT /gene="ML1997" FT /product="probable integral membrane protein" FT /note="Similar to M. tuberculosis probable integral FT membrane protein Rv0970 SW:Y970_MYCTU (P71541) (210 aa); FT Fasta score E(): 0, 52.1% identity in 213 aa overlap, and FT to Streptomyces coelicolor putative integral membrane FT protein SCM2.15C. Contains multiple possible membrane FT spanning hydrophobic domains." FT /db_xref="UniProtKB/TrEMBL:Q9CBG1" FT /protein_id="CAC30952.1" FT /translation="MIDDLLLRWVVTGLFVLSAAECGFACLACRRPWTLVPSNGLHFAM FT AIAMAVMAWPRGAQLPTTGTVVFCGLVGAWFVILATVSSRRIAERAAYAYPALMMLAMV FT WMYVIMDSHLHDHWATGHHTSPHTSMLGVDMTTTVVPASGIPGWISIINWLWFAFFCIA FT TVFWTYRSFATSRRNAGFSRYCSLHPSGQAMMSTGMAIMFGVLLFHV" FT CDS 40427..42406 FT /transl_table=11 FT /gene="ML1998" FT /product="possible membrane protein" FT /note="Similar to M. tuberculosis membrane protein Rv0102 FT SW:Y102_MYCTU (Q10897) (661 aa); Fasta score E(): 0, 70.2% FT identity in 662 aa overlap. Contains multiple possible FT membrane spanning hydrophobic domains." FT /db_xref="GOA:P53525" FT /db_xref="InterPro:IPR019108" FT /db_xref="UniProtKB/Swiss-Prot:P53525" FT /protein_id="CAC30953.1" FT /translation="MQTDEPTGTATSAIRIPPLISLRTTLMVAGLLGNVVAVAAYGLFS FT RTERYGAVGNPDPGSFIGVAEPVGYFGASLSSALCLGALIYFVMMVWPQADGLIDAQAF FT RIHLAEERVSIGWLAFALTMVVVQAANDSGVTPAELRTGAALFNAITTSETSRAWIVVT FT ICALLVTLTLRVIIRYSDHFVLLIPAVIGVIATAVTGNAGQGPDHDYATSAVIVFALAI FT AALSGLKITAALTEVTPSRAVLIVQVVCGVLALAYGAELVYLLSPGAAMIDSDFGRLGL FT VAGVLVTLVCFSDCWALVMGRPHSDHRTRLTALAMMAVTAATAAMSVQTAPRFLTHRFT FT AWDVFLGYELPQPPNIVRFFTVWRFDSLIGATAIVLGIGYVAGFVRVRRAGNTWPVGRL FT VAWLTGCVALVFTSSSGVRTYGSAMFSVHMAEHMTLNMFIPVLLVLGGPVTLALRALSA FT AGDGQQPGPREWLTWLMHSSVTAFLSHPVTNFILFVGSPYIVYFTPLFDTLVRYHWGHE FT FMAIHFLLVGYIFYWAIIGIDPGPRRLPYLARIGLLFAVMPFHAFFGIALMTMTSAISA FT EFYRSVNLPWLASIDADQHIGGAIAWSATELPVIIVIVALMAQWARQDHRVAVREDRHA FT DSTYADDDLNAYNAMLRELSRMRR" FT CDS complement(42814..43068) FT /pseudo FT /transl_table=11 FT /gene="ML1999" FT /product="putative carboxyvinyl-carboxyphosphonate FT phosphorylmutase (pseudogene)" FT CDS complement(43467..45719) FT /transl_table=11 FT /gene="ctpB" FT /gene_synonym="ML2000" FT /product="cation-transporting ATPase" FT /note="Similar to M. tuberculosis cation-transporting FT ATPase ctpB SW:CTPB_MYCTU (Q10877) (752 aa); Fasta score FT E(): 0, 77.0% identity in 752 aa overlap, and to many FT others e.g. Bacillus subtilis potential copper-transporting FT ATPase YVGX SW:ATCU_BACSU (O32220) (803 aa); Fasta score FT E(): 0, 39.8% identity in 744 aa overlap. Contains Pfam FT matches to entries PF00403 HMA, Heavy-metal-associated FT domain and PF00122 E1-E2_ATPase, E1-E2 ATPase. Also FT contains Prosite hits to PS00013 Prokaryotic membrane FT lipoprotein lipid attachment site, PS00154 E1-E2 ATPases FT phosphorylation site, PS01047 Heavy-metal-associated domain FT and PS01229 Hypothetical cof family signature 2. Contains FT multiple possible membrane spanning hydrophobic domains." FT /note="Similar to ML1987, ML0747 and ML2671" FT /db_xref="GOA:P46840" FT /db_xref="InterPro:IPR000579" FT /db_xref="InterPro:IPR001757" FT /db_xref="InterPro:IPR005834" FT /db_xref="InterPro:IPR006121" FT /db_xref="InterPro:IPR006403" FT /db_xref="InterPro:IPR006416" FT /db_xref="InterPro:IPR008250" FT /db_xref="InterPro:IPR017969" FT /db_xref="InterPro:IPR018303" FT /db_xref="UniProtKB/Swiss-Prot:P46840" FT /protein_id="CAC30955.1" FT /translation="MTASLVEDTNNNHESVRRIQLDVAGMLCAACASRVETKLNKIPGV FT RASVNFATRVATIDAVDVAVDELRQVIEQAGYRATAHAESAVEEIDPDADYARNLLRRL FT IVAALLFVPLADLSTMFAIVPTNRFPGWGYLLTALAAPIVTWAAWPFHRVALRNARYRA FT ASMETLISAGILAATGWSLSTIFVDKEPRQTHGIWQAILHSDSIYFEVAAGVTVFVLAG FT RFFEARAKSKAGSALRALAARGAKNVEVLLPNGAELTIPAGELKKQQHFLVRPGETITA FT DGVVIDGTATIDMSAITGEARPVHASPASTVVGGTTVLDGRLVIEATAVGGDTQFAAMV FT RLVEDAQVQKARVQHLADRIAAVFVPMVFVIAGLAGASWLLAGASPDRAFSVVLGVLVI FT ACPCTLGLATPTAMMVASGRGAQLGIFIKGYRALETINAIDTVVFDKTGTLTLGQLSVS FT TVTSTGGWCSGEVLALASAVEAASEHSVATAIVAAYADPRPVADFVAFAGCGVSGVVAE FT HHVKIGKPSWVTRNAPCDVVLESARREGESRGETVVFVSVDGVACGAVAIADTVKDSAA FT DAISALCSRGLHTILLTGDNQAAARAVAAQVGIDTVIADMLPEAKVDVIQRLRDQGHTV FT AMVGDGINDGPALACADLGLAMGRGTDVAIGAADLILVRDSLGVVPVALDLARATMRTI FT RINMIWAFGYNVAAIPIASSGLLNPLIAGAAMAFSSFFVVSNSLRLSNFGLSQTSD" FT misc_feature complement(43509..45080) FT /note="Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 FT ATPase, score 778.90, E-value 2e-230" FT misc_feature complement(43740..43808) FT /note="PS01229 Hypothetical cof family signature 2" FT misc_feature complement(44367..44387) FT /note="PS00154 E1-E2 ATPases phosphorylation site" FT misc_feature complement(44517..44549) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature complement(45477..45665) FT /note="Pfam match to entry PF00403 HMA, FT Heavy-metal-associated domain, score 86.40, E-value FT 3.1e-23" FT misc_feature complement(45567..45653) FT /note="PS01047 Heavy-metal-associated domain" FT CDS complement(45806..46428) FT /pseudo FT /transl_table=11 FT /gene="ML2001" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1913 (Best blastx score 204)" FT CDS 47154..47935 FT /pseudo FT /transl_table=11 FT /gene="fadB5" FT /gene_synonym="ML2002" FT /product="3-hydroxyacyl-CoA dehydrogenase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT fadB5 (Best blastx score 327)" FT CDS complement(47936..48336) FT /pseudo FT /transl_table=11 FT /gene="ML2003" FT /product="probable ketoacyl reductase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv3829c (Best blastx score 121)" FT CDS 48558..48815 FT /pseudo FT /transl_table=11 FT /gene="ML2004" FT /product="putative hydrolase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv2715" FT CDS 48912..49608 FT /pseudo FT /transl_table=11 FT /gene="ML2005" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv0021c (Best blastx score 197)" FT CDS 51079..51477 FT /pseudo FT /transl_table=11 FT /gene="ML2006" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv3368c (Best blastx score 130)" FT CDS 52008..52490 FT /pseudo FT /transl_table=11 FT /gene="ML2007" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1907c (Best blastx score 281)" FT CDS 52525..52982 FT /pseudo FT /transl_table=11 FT /gene="furA" FT /gene_synonym="ML2008" FT /product="ferric uptake regulatory protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT furA (Best blastx score 118)" FT CDS 53017..55035 FT /pseudo FT /transl_table=11 FT /gene="katG" FT /gene_synonym="ML2009" FT /product="catalase-peroxidase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT katG (Best blastx score 391)" FT CDS 55123..55584 FT /transl_table=11 FT /gene="ML2010" FT /product="putative lipoprotein" FT /note="Similar to M. tuberculosis hypothetical protein FT Rv1906c TR:O07726 (EMBL:Z97193) (156 aa); Fasta score E(): FT 2.6e-31, 63.2% identity in 155 aa overlap. Contains a FT possible N-terminal signal sequence and a PS00013 FT Prokaryotic membrane lipoprotein lipid attachment site." FT /db_xref="UniProtKB/TrEMBL:O33144" FT /protein_id="CAC30965.1" FT /translation="MWLTAAPAAARFVVASVIAASCAASTGVAGADPQSPSAPKTTIDH FT DGTYAVGTDIAPGTYSSAGPVGNGTCYWKRIDNPDGPIDNAMSKKPKIVQIEASNKAFK FT TTGCQPWQQTSNTTVSTDLPGPIAGIQLESNLGILNGLLASNGQQVPRS" FT misc_feature 55156..55188 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS 55639..56601 FT /transl_table=11 FT /gene="aao" FT /gene_synonym="ML2011" FT /product="D-amino acid oxidase" FT /note="Similar to M. tuberculosis putative D-amino acid FT oxidase aao Rv1905c TR:O07727 (EMBL:Z97193) (320 aa); Fasta FT score E(): 0, 71.4% identity in 318 aa overlap, and to many FT others e.g. Bos taurus D-aspartate oxidase SW:OXDD_BOVIN FT (X95310) (341 aa); Fasta score E(): 7e-24, 30.2% identity FT in 328 aa overlap. Contains Pfam match to entry PF01266 FT DAO, D-amino acid oxidase." FT /db_xref="GOA:Q9RIA4" FT /db_xref="InterPro:IPR006076" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9RIA4" FT /protein_id="CAC30966.1" FT /translation="MASNGQQIVVIGAGVSGLTSAVCLAEAGWPVQLWAAAMPQQTTSA FT VAGAVWAPPRPEERASTSLAWTGHSLQIFRELANDPSTGVRMAPALTVGDLPGANAMGL FT AAKLIPDLRPADLADLPDGFGAGFFGTMPMIDMPQYLDYLTARLAAAGCELETRSVRSL FT AEAADTAPIIVNCTGLGAAALANDDTVRPLFGQHVVLTNPGLQQLFLEVNNGSEWICYF FT PHPLRVVCGGISIPGRWDTTPDPAVTDRILQRCRRIEPRLGEAAVIETITGLRPDRPSP FT RVEVELSGSVRYIHNYGHSSSGVTLSWGCARDVVRLVSD" FT misc_feature 55654..56598 FT /note="Pfam match to entry PF01266 DAO, D-amino acid FT oxidase, score 524.00, E-value 1.1e-153" FT CDS complement(56619..57038) FT /transl_table=11 FT /gene="ML2012" FT /product="putative membrane protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT protein Rv1903 or MTCY180.15C TR:O07729 (EMBL:Z97193) (134 FT aa) fasta scores: E(): 0, 80.6% id in 129 aa and to FT Streptomyces coelicolor putative membrane proteins e.g. FT SCQ11.05C TR:Q9S1M9 (EMBL:AL096823) (125 aa) fasta scores: FT E(): 2.5e-15, 43.0% id in 121 aa. Previously sequenced as FT TR:O33146 (EMBL:AJ000521). Contains hydrophobic, possible FT membrane-spanning regions." FT /db_xref="InterPro:IPR007165" FT /db_xref="UniProtKB/TrEMBL:O33146" FT /protein_id="CAC30967.1" FT /translation="MARSPAVGPFLVRAALTSLALWVVTQFVHGLSFVGGNTTLQRVGI FT IFVVAVIFGLVNAIIKPIVQILSIPLYILTLGLFHVVVNALMLWITARITGNTTHWGLQ FT IDHFWWTAIWAAIVLSIVSWVLSMLIRGAGRRTCD" FT CDS complement(57506..57886) FT /transl_table=11 FT /gene="ML2013" FT /product="hypothetical protein" FT /note="no database matches." FT /db_xref="UniProtKB/TrEMBL:O33147" FT /protein_id="CAC30968.1" FT /translation="MLRDVDREHIDMMVLYPSLGFCILRLDDPDFATRLARFYNQWIGD FT YCAPTNGWLRGGGVTSMERGQVAIDITNGVKELGIAVTLIPPVLNASNLDHPYLGPFYA FT ATVERGMAISIHARYPFAADWC" FT CDS 58192..59430 FT /pseudo FT /transl_table=11 FT /gene="nanT" FT /gene_synonym="ML2014" FT /product="probable sialic acid transporter (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT nanT (Best blastx score 578)" FT CDS complement(59450..60748) FT /transl_table=11 FT /gene="cinA" FT /gene_synonym="ML2015" FT /product="competence damage protein homolog" FT /note="Similar to M. tuberculosis competence damage protein FT homolog cinA Rv1901 TR:O07731 (EMBL:Z97193) (430 aa); Fasta FT score E(): 0, 77.0% identity in 431 aa overlap, and to e.g. FT Streptococcus pneumoniae putative competence-damage protein FT SW:CINA_STRPN (P54184) (418 aa); Fasta score E(): 1.4e-22, FT 31.0% identity in 439 aa overlap." FT /db_xref="GOA:Q9X7D6" FT /db_xref="InterPro:IPR001453" FT /db_xref="InterPro:IPR008135" FT /db_xref="InterPro:IPR008136" FT /db_xref="UniProtKB/Swiss-Prot:Q9X7D6" FT /protein_id="CAC30970.1" FT /translation="MRRLMVVSARAGIVVTGTEILTGRVRDRNGPWLADRLLELGVKLA FT HITICGDCPADIEAQLRFMAEAGVDLIVTSGGLGPTADDMTVEVVARFCNREMVLDVEL FT ENKIAAILNSLMTRFNPGDFEAVRAANRKQAMIPAGSQVLDPIGTAPGLVVPGKPTVMV FT LPGPPSELQPMWRRAVMTAATREAIADRTIYRQQTLRMFGLSESGLAETLRDAQASIPG FT FDALEITTCLRRGEIEMVTRYEPDVVNVYVELTQLLRDRHGHQLYSEDGARVDDLIAHL FT LAGRRIATAESCTAGLLAARLTERPGSSDYVAGALVAYSNEAKVTLLGVDPALIAEHGE FT VSEPVVEAMAAGALQRFDVDTAAAISGIAGPGGGTAEKPIGTVCFTVMLADGGPTLTRT FT LRLPGNRSDIRERSTTVAMHLLRHALSDTDSVP" FT CDS 60778..61965 FT /pseudo FT /transl_table=11 FT /gene="lipJ" FT /gene_synonym="ML2016" FT /product="probable esterase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT lipJ (Best blastx score 394)" FT repeat_region 61944..62096 FT /note="153 bp repeat, 95% identical to region FT 208823..208975 " FT CDS 62175..62645 FT /pseudo FT /transl_table=11 FT /gene="lppD" FT /gene_synonym="ML2017" FT /product="lipoprotein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT lppD (Best blastx score 230)" FT CDS complement(62694..62847) FT /pseudo FT /transl_table=11 FT /gene="ML2018" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1898 (Best blastx score 80)" FT CDS 62933..63352 FT /pseudo FT /transl_table=11 FT /gene="ML2019" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1897c (Best blastx score 256)" FT CDS 63465..64379 FT /transl_table=11 FT /gene="ML2020" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis conserved hypothetical FT protein Rv1896c TR:O07736 (EMBL:Z97193) (303 aa); Fasta FT score E(): 0, 78.0% identity in 300 aa overlap, and to many FT other M. tuberculosis hypothetical proteins e.g. Rv3399 FT SW:YX99_MYCTU (Z77165) (348 aa); Fasta score E(): 0, 41.4% FT identity in 304 aa overlap." FT /note="Similar to ML2640 and ML2539" FT /db_xref="GOA:Q9CBG0" FT /db_xref="InterPro:IPR003455" FT /db_xref="InterPro:IPR011610" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBG0" FT /protein_id="CAC30975.1" FT /translation="MMAATPEFGSLRSDDDHWDIVSSVGYTALLVAGWRALHAVGPQPL FT VRDEYAKYFITASRDPYLMNLLANPGTSLNETAFPRLYGVQTRFFDDFFSSAGDTGIRQ FT AVIVAAGLDSRAYRLKWPNGATVFEIDLPKVLEFKARVLAEQGAIPNAGRSEVAADLRA FT DWPRALKAAGFDPQRSSAWSVEGLLPYLTNDAQSALFTRIGELCAPGSRIAVGALGSRL FT DRKQLAALEATHPGVNISGDVDFSALTYEPKTDSAQWLAAHGWAVEPVRNTLELQTSYG FT MTPPDVDVQMDSFMHSQYITATR" FT CDS 64667..65735 FT /pseudo FT /transl_table=11 FT /gene="ML2021" FT /product="some similarity to dioxygenases (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1894c (Best blastx score 252)" FT CDS complement(65794..66318) FT /transl_table=11 FT /gene="ML2022" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis hypothetical protein FT Rv1893 TR:O07739 (EMBL:Z97193) (72 aa); Fasta score E(): FT 3e-13, 69.4% identity in 72 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9CBF9" FT /protein_id="CAC30977.1" FT /translation="MSGPSSSCRCLPCCPHDRSSQPRCGESLGWQGYGRVYLESPWPFG FT LKQILQILRYGAEYAGKILAQPSKPTDVSSGPRRKTQVFAKATVVPKILQPKETQMTFD FT PKNAVNAARDIATNFVEKASDIVENVSDIIKGDIAGGANDIVQNSIDIATHAVDKAKEI FT FIGKGEYDELE" FT CDS complement(66414..66818) FT /transl_table=11 FT /gene="ML2023" FT /product="putative secreted protein" FT /note="Similar to M. tuberculosis hypothetical protein FT Rv1891 TR:O07741 (EMBL:Z97193) (135 aa); Fasta score E(): FT 0, 79.7% identity in 133 aa overlap. Contains probable FT N-terminal signal sequence." FT /db_xref="UniProtKB/TrEMBL:Q9X7D3" FT /protein_id="CAC30978.1" FT /translation="MIRELLAISAIASGAVNSAPRAAANPHYDGDVPGMSYDASLSAPC FT FSWERYIFGRGPSGQAEACHFPPPNQFPPANTGYWVISYPLYGVQQAGAPCPKTQAAAQ FT SADGLPMLCLGGQGWQPGWFTDKGFFPPAG" FT CDS 67171..68377 FT /pseudo FT /transl_table=11 FT /gene="ML2024" FT /product="cytochrome p450 (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv3545c (Best blastx score 411)" FT CDS 68619..68909 FT /pseudo FT /transl_table=11 FT /gene="ML2025" FT /product="alcohol dehydrogenase (pseudogene)" FT /note="Similar to part of e.g. Emericella nidulans alcohol FT dehydrogenase II SW:ADH2_EMENI (P54202) fasta scores: E(): FT 0.00049, 31.1% in 74 aa" FT CDS 69411..69915 FT /pseudo FT /transl_table=11 FT /gene="ML2026" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1890c (Best blastx score 232)" FT CDS complement(69972..70585) FT /pseudo FT /transl_table=11 FT /gene="ML2027" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1887 (Best blastx score 238)" FT CDS 70770..71753 FT /transl_table=11 FT /gene="fbpB" FT /gene_synonym="ML2028" FT /product="antigen 85A, mycolyltransferase" FT /note="Similar to Mycobacterium kansasii antigen 85-B FT precursor SW:A85B_MYCKA (P21160) fasta scores: E(): 0, FT 85.8% in 324 aa, and to Mycobacterium avium antigen 85-B FT precursor SW:A85B_MYCAV (Q06947) fasta scores: E(): 0, FT 81.2% in 329 aa. Contains Pfam match to entry PF00756 FT Esterase, Putative esterase." FT /note="Similar to ML0097, ML2655 and ML0098" FT /db_xref="GOA:P31951" FT /db_xref="InterPro:IPR000801" FT /db_xref="UniProtKB/Swiss-Prot:P31951" FT /protein_id="CAC30983.1" FT /translation="MIDVSGKIRAWGRWLLVGAAATLPSLISLAGGAATASAFSRPGLP FT VEYLQVPSEAMGRSIKVQFQNGGNGSPAVYLLDGLRAQDDYNGWDINTSAFEWYYQSGL FT SVVMPVGGQSSFYSDWYSPACGKAGCTTYKWETFLTSELPKWLSANRSVKSTGSAVVGL FT SMAGSSALILAAYHPDQFIYAGSLSALMDSSQGIEPQLIGLAMGDAGGYKAADMWGPPN FT DPAWQRNDPILQAGKLVANNTHLWVYCGNGTPSELGGTNVPAEFLENFVHGSNLKFQDA FT YNGAGGHNAVFNLNADGTHSWEYWGAQLNAMKPDLQNTLMAVPRSG" FT misc_feature 70848..71504 FT /note="Pfam match to entry PF00756 Esterase, Putative FT esterase, score 375.10, E-value 7.4e-109" FT CDS 72147..72697 FT /pseudo FT /transl_table=11 FT /gene="ML2029" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1885c (Best blastx score 180)" FT CDS 72797..73270 FT /transl_table=11 FT /gene="ML2030" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT proteins: TR:O07747 (EMBL:Z97193) fasta scores: E(): 0, FT 70.2% in 141 aa and TR:P71755 (EMBL:Z81368) fasta scores: FT E(): 2.8e-20, 47.9% in 121 aa." FT /note="Similar to ML2151 and ML0240" FT /db_xref="GOA:Q9CBF8" FT /db_xref="InterPro:IPR010618" FT /db_xref="UniProtKB/TrEMBL:Q9CBF8" FT /protein_id="CAC30985.1" FT /translation="MDMPGEMLDVRKLCKLFVKSAVVSGIVTASMALSTSTGMANAVPR FT EPNWDAVAQCESGRNWRANTGNGFYGGLQFKPTIWARYGGVGNPAGASREQQITVANRV FT LADQGLDAWPKCGAASDLPITLWSHPAQGVKQIINDIIQMGDTTLAAIALNGL" FT CDS 73301..73756 FT /transl_table=11 FT /gene="ML2031" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT protein TR:O07748 (EMBL:Z97193) fasta scores: E(): 0, 76.2% FT in 151 aa, and to Streptomyces actuosus NSH-OrfB TR:P72384 FT (EMBL:U75434) fasta scores: E(): 2.5e-08, 34.4% in 125 aa." FT /db_xref="InterPro:IPR005031" FT /db_xref="UniProtKB/TrEMBL:Q9CBF7" FT /protein_id="CAC30986.1" FT /translation="MEGSVTVHMAAPADKVWNLIADVRNTGRFSPETFEAEWLDDVTGP FT ALNAKFRGHVRRNEIGPVYWTTCKVTACEPGREFGFTVLLGNKPVNNWHYRLVTSGDGT FT YVTESFRFNRSPLLTVYWLLGGFLRKRRNIRDMTKTLRRIKDVVEAE" FT CDS 73904..74309 FT /pseudo FT /transl_table=11 FT /gene="lppE" FT /gene_synonym="ML2032" FT /product="lipoprotein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT lppE (Best blastx score 135)" FT CDS 74905..76209 FT /pseudo FT /transl_table=11 FT /gene="ML2033" FT /product="Similar to 6-deoxyerythronolide beta hydroxylase FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1880c (Best blastx score 323)" FT CDS 76945..77195 FT /pseudo FT /transl_table=11 FT /gene="ML2034" FT /product="putative methyltransferase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv2675c (Best blastx score 77)" FT CDS complement(77316..77579) FT /transl_table=11 FT /gene="ML2035" FT /product="hypothetical protein" FT /note="no database matches." FT /db_xref="UniProtKB/TrEMBL:Q9CBF6" FT /protein_id="CAC30990.1" FT /translation="MRDVILEGGLYVTEMRCTHALVDGPRPSLPKSIDEGRWDRTDRHV FT HLEVIRQEPNNGLVDPAAASSKPDWNPCSLYVPGRQYRNEPH" FT CDS complement(78888..79894) FT /pseudo FT /transl_table=11 FT /gene="ML2036" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1879 (Best blastx score 279)" FT CDS complement(80107..80406) FT /pseudo FT /transl_table=11 FT /gene="glnA3" FT /gene_synonym="ML2037" FT /product="probable glutamine synthase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT glnA3 (Best blastx score 129)" FT CDS complement(81473..81952) FT /transl_table=11 FT /gene="bfrA" FT /gene_synonym="ML2038" FT /product="bacterioferritin" FT /note="Similar to Mycobacterium tuberculosis FT bacterioferritin SW:BFR_MYCTU (O08465) fasta scores: E(): FT 0, 90.1% in 152 aa, and to Brucella melitensis FT bacterioferritin SW:BFR_BRUME (P49944) fasta scores: E(): FT 8.5e-23, 44.6% in 139 aa. Contains Pfam match to entry FT PF01334 Bacteriofer, Bacterioferritin." FT /db_xref="GOA:P43315" FT /db_xref="InterPro:IPR002024" FT /db_xref="InterPro:IPR008331" FT /db_xref="InterPro:IPR009040" FT /db_xref="InterPro:IPR009078" FT /db_xref="InterPro:IPR012347" FT /db_xref="UniProtKB/Swiss-Prot:P43315" FT /protein_id="CAC30993.1" FT /translation="MQGDPDVLRLLNEQLTSELTAINQYFLHSKMQENWGFTELAERTR FT VESFDEMRHAEAITDRILLLDGLPNYQRIGSLRVGQTLREQFEADLAIEYEVMSRLKPG FT IIMCREKQDSTSAVLLEKIVADEEEHIDYLETQLALMGQLGEELYSAQCVSRPPS" FT misc_feature complement(81491..81931) FT /note="Pfam match to entry PF01334 Bacteriofer, FT Bacterioferritin, score 305.50, E-value 6.3e-88" FT CDS complement(82888..83342) FT /pseudo FT /transl_table=11 FT /gene="ML2039" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1875 (Best blastx score 120)" FT CDS complement(83380..84022) FT /pseudo FT /transl_table=11 FT /gene="ML2040" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1874 (Best blastx score 169)" FT CDS complement(84134..85069) FT /transl_table=11 FT /gene="oxyR" FT /gene_synonym="ML2041" FT /product="probable LysR-family transcriptional regulator" FT /note="Identical to Mycobacterium leprae probable hydrogen FT peroxide-inducible gene activator SW:OXYR_MYCLE (P52678) FT fasta scores: E(): 0, 100.0% in 311 aa and to Escherichia FT coli SW:OXYR_ECOLI (P11721; P22471) fasta scores: E(): FT 8.1e-33, 37.5% in 288 aa. Contains a probable FT helix-turn-helix motif at aa 23-44 (Score 1404, SD +3.97) FT Contains Pfam match to entry PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix protein, lysR family. Contains FT PS00044 Bacterial regulatory proteins." FT /note="Similar to and ML2663" FT /db_xref="GOA:P52678" FT /db_xref="InterPro:IPR000847" FT /db_xref="InterPro:IPR005119" FT /db_xref="UniProtKB/Swiss-Prot:P52678" FT /protein_id="CAC30996.1" FT /translation="MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAA FT LESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGMRLGL FT IPTVAPYVLPTMLTGLTHRLPTLTLRVVEDQTEHLLTALREGALDAAMIALPVETAGIA FT EIPIYDEDFVLALPPGHPLSGKRRVPTTALAQLPLLLLDEGHCLRDQTLDICRKSGVQA FT ELANTRAASLATAVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFR FT SASGRSASYRQIAKIIGELISTEHHVRLVA" FT misc_feature complement(84614..85042) FT /note="Pfam match to entry PF00126 HTH_1, Bacterial FT regulatory helix-turn-helix protein, lysR family, score FT 152.30, E-value 8.2e-42" FT misc_feature complement(84908..85000) FT /note="PS00044 Bacterial regulatory proteins" FT CDS 85179..85766 FT /transl_table=11 FT /gene="ahpC" FT /gene_synonym="ML2042" FT /product="alkyl hydroperoxide reductase" FT /note="Similar to Mycobacterium avium alkyl hydroperoxidase FT C TR:Q57413 (EMBL:U18263) fasta scores: E(): 0, 86.2% in FT 195 aa, and to Streptomyces viridosporus alkyl FT hydroperoxide reductase TR:Q9X5V0 (EMBL:AF127576) fasta FT scores: E(): 0, 58.7% in 189 aa. Contains Pfam match to FT entry PF00578 AhpC-TSA, AhpC/TSA family." FT /db_xref="GOA:Q9CBF5" FT /db_xref="HSSP:1E2Y" FT /db_xref="InterPro:IPR000866" FT /db_xref="InterPro:IPR012335" FT /db_xref="InterPro:IPR012336" FT /db_xref="InterPro:IPR017936" FT /db_xref="UniProtKB/TrEMBL:Q9CBF5" FT /protein_id="CAC30997.1" FT /translation="MSLLSIGQQFPAYQLTALIGGDLSKVDAQQPGDYFTTVSSDSHPG FT KWRVVFFWPKDFTFICPTEIAAFGKLNEEFEGRGAQILGVSIDSEFVHFQWRAQHEDLK FT RLPFPMLSDIKRELSAASGALNADGVADRVTFIVDPDNDIQFVSVTAGSVGRNVEEVLR FT VLDALQSDQLCACNWRKGDPTLNATELLKTSA" FT misc_feature 85194..85667 FT /note="Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA FT family, score 166.10, E-value 6.1e-46" FT CDS 85806..86280 FT /pseudo FT /transl_table=11 FT /gene="ahpD" FT /gene_synonym="ML2043" FT /product="member of AhpC/TSA family (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT ahpD (Best blastx score 150)" FT CDS complement(86518..86739) FT /transl_table=11 FT /gene="ML2044" FT /product="hypothetical protein" FT /note="no database matches." FT /db_xref="UniProtKB/TrEMBL:Q9CBF4" FT /protein_id="CAC30999.1" FT /translation="METIVLPETSVPTPLLCGALRIVFPVHADVIKHAVEQNTQAPAVR FT FGEQLVEVGVVTEPGIDTCSGRWCRSHL" FT CDS 87148..87405 FT /transl_table=11 FT /gene="ML2045" FT /product="hypothetical protein" FT /note="no database matches." FT /db_xref="InterPro:IPR017853" FT /db_xref="UniProtKB/TrEMBL:Q9CBF3" FT /protein_id="CAC31000.1" FT /translation="MSRIASQLGQPEHLTHALIILLTVAGVPSVYAGDEFGFRGLKEER FT YGVDDAVLPEFFSPPMQLDVFGVHAWALHQYLIGLRRRHP" FT CDS 87709..88953 FT /transl_table=11 FT /gene="lldD2" FT /gene_synonym="ML2046" FT /product="L-lactate dehydrogenase" FT /note="Similar to Mycobacterium tuberculosis LLDD2 FT TR:P95143 (EMBL:AQ102036) fasta scores: E(): 0, 85.0% in FT 413 aa, and to Escherichia coli L-lactate dehydrogenase FT SW:LLDD_ECOLI (P33232) fasta scores: E(): 0, 37.3% in 383 FT aa. Contains Pfam match to entry PF01070 FMN_dh, FT FMN-dependent dehydrogenase. Contains PS00557 FMN-dependent FT alpha-hydroxy acid dehydrogenases active site." FT /db_xref="GOA:Q9CBF2" FT /db_xref="HSSP:1AL8" FT /db_xref="InterPro:IPR000262" FT /db_xref="InterPro:IPR008259" FT /db_xref="InterPro:IPR012133" FT /db_xref="InterPro:IPR013785" FT /db_xref="InterPro:IPR017934" FT /db_xref="UniProtKB/TrEMBL:Q9CBF2" FT /protein_id="CAC31001.1" FT /translation="MAAKRRMPRVHDLAPLIQFKRPKFGATKRRLEAALTIQDLRCIAK FT QRTPKAAFDYTDGAAEDELSIKRAQQAFRDIEFHPAILRDVTNVCAGWDVLGHSVLLPF FT GIAPTGFTRLMHTEGEIAGARAAAAAGIPFSLSTLATSAIEDVVAAVPQGRKWFQLYMW FT RDRDRSMALVERAADAGYDALLVTVDVPVAGARLRDTRNGMSIPPALTLRTVFDALPHP FT RWWIDLLTTEPLAFASLDRWSGTVSDYLNTMFDPSVTFDDLAWIKTQWPGKFVVKGIQT FT LDDARAVVERGIDGVVLSNHGGRQLDRAPVPFHLLPTVAREFGKDTEILLDTGIMSGAD FT IVAAIALGARCTLVGRAYLYGLMAGGEAGVRRAIEILESGVIRTMQLLGVTCLEELSPR FT HVTQLQRLGPIEPPA" FT misc_feature 87838..88917 FT /note="Pfam match to entry PF01070 FMN_dh, FMN-dependent FT dehydrogenase, score 448.10, E-value 7.6e-131" FT misc_feature 88603..88623 FT /note="PS00557 FMN-dependent alpha-hydroxy acid FT dehydrogenases active site" FT CDS 89356..89673 FT /pseudo FT /transl_table=11 FT /gene="ML2047" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv1991c (Best blastx score 129)" FT CDS 89955..90212 FT /transl_table=11 FT /gene="ML2048" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT protein TR:P95144 (EMBL:AL204060) fasta scores: E(): FT 4.7e-16, 62.0% in 79 aa, and to Streptomyces coelicolor FT hypothetical protein TR:CAB88434 (EMBL:AL353815) fasta FT scores: E(): 0.0092, 39.3% in 61 aa; truncated at FT C-terminus; may represent a pseudogene." FT /db_xref="UniProtKB/TrEMBL:Q7AQ01" FT /protein_id="CAC31003.1" FT /translation="MTNLWDLKQKVIYSIQWLVVNSLGHQLPRTMLETIRRKTGQPWRT FT AAGVHPVDNQFGMVCENSEYSDYVYNIKANTAVRTHKSKI" FT CDS 90604..91206 FT /pseudo FT /transl_table=11 FT /gene="ML2049" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1870c (Best blastx score 365)" FT CDS 91310..92258 FT /pseudo FT /transl_table=11 FT /gene="ML2050" FT /product="probable reductase (like rhodocoxin reductase) FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1869c (Best blastx score 450)" FT CDS 92259..92594 FT /pseudo FT /transl_table=11 FT /gene="ML2051" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1864c" FT CDS 92570..93238 FT /pseudo FT /transl_table=11 FT /gene="ML2052" FT /product="probable membrane protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1863c (Best blastx score 190)" FT CDS complement(93247..94254) FT /transl_table=11 FT /gene="ML2053" FT /product="putative alcohol dehydrogenase" FT /note="Similar to Mycobacterium tuberculosis adhA or Rv1862 FT or MTCY359.11 TR:P95153 (EMBL:Z83859) (346 aa) fasta FT scores: E(): 0, 84.5% id in 336 aa. Similar to Rhizobium FT meliloti alcohol dehydrogenase adhA SW:ADHA_RHIME (O31186) FT (340 aa) fasta scores: E(): 6.3e-26, 33.1% id in 344 aa and FT many putative alcohol dehydrogenases. Contains Pfam match FT to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. FT Contains PS00059 Zinc-containing alcohol dehydrogenases FT signature." FT /note="Similar to ML1730, ML1784 and ML2025" FT /db_xref="GOA:Q9CBF1" FT /db_xref="HSSP:1NTO" FT /db_xref="InterPro:IPR002085" FT /db_xref="InterPro:IPR002328" FT /db_xref="InterPro:IPR011032" FT /db_xref="InterPro:IPR013149" FT /db_xref="InterPro:IPR013154" FT /db_xref="InterPro:IPR014187" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9CBF1" FT /protein_id="CAC31008.1" FT /translation="MHAWRVRRPGPIQTSPLEWVTTEVPCPEPSELLVAVRACGVCRTD FT LHVAEGDLPVHREHVTPGHEVVGEVLGVGSDVDAAAGFDVGDRVGIAWLRYTCGVCNYC FT RSGTENLCVQSRYTGWDVDGGYAEFTTVPAAFAHHLPSGYSDCELAPLLCAGIIGYRSL FT LRSELPPGGRLGIYGFGGSAHIAAQVALVQGAEVHVMTRGARAQELALELGAASAQGVA FT DLPPVPLDAAIVFAPVGDLVLPACEALNRGGTLAIAGIHLSDIPQLNYQRHLFQERQIR FT SVTSNTRADARAFLDFAAQHHIAVTTPEYPLEQADQALTDLSVGRISGAAVLLA" FT misc_feature complement(93253..94236) FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score 184.40, E-value 1.8e-51" FT misc_feature complement(94024..94068) FT /note="PS00059 Zinc-containing alcohol dehydrogenases FT signature" FT CDS complement(94332..94631) FT /transl_table=11 FT /gene="ML2054" FT /product="integral membrane protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT protein TR:P95154 (EMBL:Z83859) fasta scores: E(): 6.4e-18, FT 58.4% in 101 aa, and to Escherichia coli transglycosylase FT associated protein SW:TAG1_ECOLI (P76011) fasta scores: FT E(): 0.0054, 35.1% in 77 aa." FT /db_xref="GOA:Q9CBF0" FT /db_xref="InterPro:IPR007341" FT /db_xref="UniProtKB/TrEMBL:Q9CBF0" FT /protein_id="CAC31009.1" FT /translation="MDVMAATEYLARSTTLTSVGWIGYIIIGGIAGWIAGKIVQGGGSG FT ILMNIVIGVVGALIGGFLLSFFVNTAAGGWWFTLFTSILGSVILLWVVGRVRKT" FT CDS complement(94791..95654) FT /transl_table=11 FT /gene="modD" FT /gene_synonym="ML2055" FT /product="probable cell surface protein (associated with FT virulence)" FT /note="Previously sequenced Mycobacterium leprae Fap-l FT fibronectin attachment protein important in virulence for FT the efficient invasion of epithelial and Schwann cells, FT TR:Q9R5V6 fasta scores: E(): 0, 100.0% in 287 aa. The FT product of this CDS has also been shown to be highly FT immunogenic, Mycobacterium leprae molybdate uptake protein FT SW:MODD_MYCLE (P46842) fasta scores: E(): 0, 99.3% in 287 FT aa, and highly similar to several proteins involved in the FT uptake of molybdenum in other mycobacteria e.g. FT Mycobacterium tuberculosis molybdate uptake secreted FT protein precursor SW:MODD_MYCTU (Q50906; O08062) fasta FT scores: E(): 0, 66.8% in 298 aa. Contains a possible FT N-terminal signal sequence." FT /db_xref="GOA:P46842" FT /db_xref="InterPro:IPR010801" FT /db_xref="UniProtKB/Swiss-Prot:P46842" FT /protein_id="CAC31010.1" FT /translation="MNQVDLDSTHRKGLWAILAIAVVASASAFTMPLPAAANADPAPLP FT PSTATAAPSPAQEIITPLPGAPVSSEAQPGDPNAPSLDPNAPYPLAVDPNAGRITNAVG FT GFSFVLPAGWVESEASHLDYGSVLLSKAIEQPPVLGQPTVVATDTRIVLGRLDQKLYAS FT AEADNIKAAVRLGSDMGEFYLPYPGTRINQETIPLHANGIAGSASYYEVKFSDPNKPIG FT QICTSVVGSPAASTPDVGPSQRWFVVWLGTSNNPVDKGAAKELAESIRSEMAPIPASVS FT APAPVG" FT CDS complement(95773..96865) FT /pseudo FT /transl_table=11 FT /gene="modC" FT /gene_synonym="ML2056" FT /product="molybdate uptake ABC-transporter (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT modC (Best blastx score 272)" FT CDS complement(96874..97666) FT /pseudo FT /transl_table=11 FT /gene="modB" FT /gene_synonym="ML2057" FT /product="transport system permease, molybdate uptake FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT modB (Best blastx score 427)" FT CDS complement(97696..98468) FT /pseudo FT /transl_table=11 FT /gene="modA" FT /gene_synonym="ML2058" FT /product="molybdate binding protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT modA (Best blastx score 260)" FT CDS 98706..99380 FT /transl_table=11 FT /gene="ML2059" FT /product="short-chain dehydrogenase/reductase family" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 23.2 kda protein TR:P95158 (EMBL:Z83859) fasta scores: E(): FT 0, 80.5% in 220 aa, and to Streptomyces argillaceus FT ketoreductase TR:O86486 (EMBL:AJ007932) fasta scores: E(): FT 0.00044, 24.9% in 201 aa. Contains Pfam match to entry FT PF00678 adh_short_C2, Short chain dehydrogenase/reductase FT C-terminus." FT /db_xref="GOA:O32906" FT /db_xref="InterPro:IPR002198" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:O32906" FT /protein_id="CAC31014.1" FT /translation="MAVDVLVTGGNTDLGRTIAEGFRNDGHKVTLVGPRRADLEVVAKE FT LDVDTIVCNTTDPASLDEARGLFPRHLNTIVNVPTLGFDTGDPRTFSLSDTANAWHNEL FT DATVLSAVLTVQSVGDHLRSGGSIIGVLAENPPAGSVDAAIKAALSSWVAGQAGVFGTR FT GITVNAIACGRSVQAGYEGLSRMPPHVATEITRLALFLTTPASRHITGQTLHVSHGALT FT HF" FT misc_feature 99276..99353 FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 21.30, FT E-value 0.00028" FT CDS 99448..100395 FT /pseudo FT /transl_table=11 FT /gene="ML2060" FT /product="probable monooxygenase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1855c (Best blastx score 359)" FT CDS 100572..101972 FT /transl_table=11 FT /gene="ML2061" FT /product="possible dehydrogenase" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 49.6 kda protein TR:P95160 (EMBL:Z83859) fasta scores: E(): FT 0, 90.2% in 460 aa, and to Corynebacterium glutamicum NADH FT dehydrogenase TR:Q9X710 (EMBL:AJ238250) fasta scores: E(): FT 0, 56.5% in 455 aa. Contains Pfam match to entry PF00070 FT pyr_redox, Pyridine nucleotide-disulphide oxidoreductase." FT /db_xref="GOA:O32907" FT /db_xref="InterPro:IPR001327" FT /db_xref="InterPro:IPR013027" FT /db_xref="UniProtKB/TrEMBL:O32907" FT /protein_id="CAC31016.1" FT /translation="MNAQPAATAAQDRRHQVVIIGSGFGGLNAAKKLKRANVDIKLIAR FT TTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQRNIQVLLGNVTHIDLANQCVVSELL FT GHTYETLYDSLIVAAGAGQSYFGNDQFAEFAPGMKSIDDALELRGRILSAFEQAERSND FT PERREKLLTFTVVGAGPTGVEMAGQIAELADHTLKGAFRRIDSTKARVVLLDAAPAVLP FT PMGEKLGQRAAARLQKMGVEIQLSAMVTDVDRNGITVQDSDGTVRRIESACKVWSAGVS FT ASRLGRDLAEQSLVELDWAGRVKVLPDLSIPGYRNVFVVGDMAAIDGVPGVAQGAIQGA FT KYVANNIKAELGEANPAEREPFQYFDKGSMATVSRFSAVAKIGPLEFSGFIAWLMWLVL FT HLMYLIGFKTKITTLLSWTVTFLSTRRGQLTITEQQAFARTRLEQLAELTAESQSTAAA FT NRATMRAS" FT misc_feature 100620..101540 FT /note="Pfam match to entry PF00070 pyr_redox, Pyridine FT nucleotide-disulphide oxidoreductase, score 125.70, E-value FT 2.3e-36" FT CDS complement(102188..102419) FT /pseudo FT /transl_table=11 FT /gene="ML2062" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1847 (Best blastx score 84)" FT CDS 102806..103234 FT /transl_table=11 FT /gene="ML2063" FT /product="possible regulator" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 15.2 kda protein TR:P95163 (EMBL:AL008609) fasta scores: FT E(): 0, 95.1% in 123 aa, and weakly to Bacillus FT licheniformis penicillinase repressor SW:BLAI_BACLI FT (P06555; P12286) fasta scores: E(): 1.1, 21.7% in 129 aa." FT /db_xref="GOA:O32909" FT /db_xref="InterPro:IPR005650" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:O32909" FT /protein_id="CAC31018.1" FT /translation="MAKLTRLGDLERAVMDHLWSRQEPQTVRQVHEALSARRDLAYTTV FT MTVLQRLAKKNLVSQIRNNRAHRYAPVHGRDELVAGLMVDALDQAEDSDSRQAALVHFV FT ERVGADEADALRRALAELETHQRHVRHLVALQRTTEGD" FT CDS 103239..104189 FT /transl_table=11 FT /gene="ML2064" FT /product="integral membrane protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 32.7 kda protein TR:P95164 (EMBL:Z83859) fasta scores: E(): FT 0, 87.6% in 314 aa, and to Streptomyces coelicolor putative FT integral membrane protein SC10A7.04 TR:Q9XAS1 FT (EMBL:AL078618) fasta scores: E(): 1.8e-19, 32.6% in 328 FT aa." FT /db_xref="GOA:O32910" FT /db_xref="InterPro:IPR001915" FT /db_xref="UniProtKB/TrEMBL:O32910" FT /protein_id="CAC31019.1" FT /translation="MSALAFTILAVLLVGPTPTLVARSTWPLRAPRAAMVLWQTIALAA FT ALSTFSAGIAIASRVLMPGPDGRLTASVIGAAGRLGWPLWAAYVAAFALTVLVGARLIV FT AIVRVAIATRRRRAHHRMVVDLVGVGHNAALAQPCARARDLRVLEVAQPLAYCLPGVRS FT RVVVSEGALTKLNDTEVTAILTHERAHLRARHDLVLEAFTAVHAAFPRLVRSSAALSAV FT RLLVELLADDAAVRAAGRTPLARALVACASGQAPSGALAAGGNTTVLRVRRLSGRSNSA FT VVSAAAYLAAAIVLLVPTVALAVPWLTELQRLFNI" FT CDS 104329..105780 FT /transl_table=11 FT /gene="gnd" FT /gene_synonym="ML2065" FT /product="6-phosphogluconate dehydrogenase" FT /note="Similar to Mycobacterium tuberculosis cosmid gnd FT TR:P95165 (EMBL:AL008609) fasta scores: E(): 0, 86.8% in FT 485 aa and to Bacillus subtilis 6-phosphogluconate FT dehydrogenase, decarboxylating II SW:6PG2_BACSU (P80859; FT P54546) fasta scores: E(): 0, 55.7% in 465 aa. Contains FT Pfam match to entry PF00393 6PGD, 6-phosphogluconate FT dehydrogenases." FT /db_xref="GOA:Q9CBE9" FT /db_xref="HSSP:2PGD" FT /db_xref="InterPro:IPR006113" FT /db_xref="InterPro:IPR006114" FT /db_xref="InterPro:IPR006115" FT /db_xref="InterPro:IPR006183" FT /db_xref="InterPro:IPR006184" FT /db_xref="InterPro:IPR008927" FT /db_xref="InterPro:IPR012284" FT /db_xref="InterPro:IPR013328" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9CBE9" FT /protein_id="CAC31020.1" FT /translation="MSAPESKTAIAQIGVTGLAVMGSNIARNFARHGYTVALHNRSIAK FT TDTLLKEHGSEGNFVRTETIPEFLAALQTPRRVLIMVKAGDATDAVINELADVMEPSDI FT IIDGGNSLFTDTIRREKAMRERGLHFVGAGISGGEEGALNGPSIMPGGPAESYTSLGPL FT LEEISAHVDGVSCCTHIGPGGSGHFVKMVHNGIEYSDMQLIGEAYQLLRDGLGMSAPQI FT ADVFTEWNRGDLNSYLVEITAEVLRQTDIKTGRPLVDVILDKAEQKGTGRWTVQSALDL FT GVPITGIAEAVFARALSGSVLQRKAAIGLASGKLGNKPTDRETFIEDVRQALYASKIVA FT YAQGFNHIQTGSTEFGWNITPGDLATIWRGGCIIRAKFLNRIKEAFDAAPDLASLIVAP FT YFRSAVESAIDSWRRVVSTATQLGIPNPGFSSALSYYDALRTERLPAALTQAQRDFFGA FT HSYGRVDARGKFHTLWSEDRSEVTV" FT misc_feature 104383..105717 FT /note="Pfam match to entry PF00393 6PGD, 6-phosphogluconate FT dehydrogenases, score 815.70, E-value 1.7e-241" FT misc_feature 105850..106125 FT /note="Pfam match to entry PF01574 IMPDH_N, IMP FT dehydrogenase / GMP reductase N terminus, score 34.30, FT E-value 2.6e-07" FT CDS 105850..107286 FT /transl_table=11 FT /gene="guaB1" FT /gene_synonym="ML2066" FT /product="inosine-5'-monophosphate dehydrogenase" FT /note="Previously sequenced as TR:O32912 (EMBL:AL008609) FT fasta scores: E(): 0, 100.0% in 478 aa. Similar to FT Mycobacterium tuberculosis inosine-5'-monophosphate FT dehydrogenase rv1843c SW:YI43_MYCTU (Q50591) fasta scores: FT E(): 0, 86.4% in 478 aa, and to Bacillus subtilis FT inosine-5'-monophosphate dehydrogenase SW:IMDH_BACSU FT (P21879) fasta scores: E(): 0, 37.7% in 472 aa. Contains 2 FT Pfam matches to entry PF00571 CBS, CBS domain. Contains FT Pfam match to entry PF00478 IMPDH_C, IMP dehydrogenase / FT GMP reductase C terminus. Contains Pfam match to entry FT PF01574 IMPDH_N, IMP dehydrogenase / GMP reductase N FT terminus." FT /note="Similar to ML0387 and ML0388" FT /db_xref="GOA:O32912" FT /db_xref="InterPro:IPR000644" FT /db_xref="InterPro:IPR001093" FT /db_xref="InterPro:IPR005991" FT /db_xref="InterPro:IPR013785" FT /db_xref="InterPro:IPR018529" FT /db_xref="UniProtKB/Swiss-Prot:O32912" FT /protein_id="CAC31021.1" FT /translation="MRFLDGHQPRFDLTYKDVFIVPHRSDVASRFDVDLSTYDGSGTTI FT PVVVANMTTVAGQRMAETVARRGGLVILPQDLPIATVQQAVEFVKSRDLVIDTPVLLTP FT NDSVSDATTLIHKRAHGVAVVAFEGRPIGLVRESSCLGVDRFTRVRDVATTDFVTAPVG FT TDPRKIFDLLEHAPIDVAVLTNADGTLAGVLTRTGAIRAGIYTPATDARGRLRIGAAVG FT INGDVAGKAQSLAEAGVDVLVVDTAHGYQVKTLEAIKCVASLNLGVPLVAGNVVSAEGT FT RELLNAGATIVKVGVGPGAMCTTRMMTGVGRPQFSAVLECASAARKLNRHVWADGGVRH FT PRDVALALAAGASNVMIGSWFAGTYESPGDLMRDRHDQPYKESYGMASKRAVVARTVAD FT SSFDRARKALFDEGISTSRMGLDPDHGGVEDLIDHITSGVRSTCTYVGASTLAELHEKA FT VVGVQSAAGFAEGHPLPSGW" FT misc_feature 106126..106284 FT /note="Pfam match to entry PF00571 CBS, CBS domain, score FT 24.00, E-value 0.0034" FT misc_feature 106300..106461 FT /note="Pfam match to entry PF00571 CBS, CBS domain, score FT 33.10, E-value 6.5e-06" FT misc_feature 106546..107223 FT /note="Pfam match to entry PF00478 IMPDH_C, IMP FT dehydrogenase / GMP reductase C terminus, score 231.30, FT E-value 1.4e-65" FT CDS 107541..108843 FT /pseudo FT /transl_table=11 FT /gene="ML2067" FT /product="possible membrane protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1842c (Best blastx score 692)" FT CDS 108843..109790 FT /pseudo FT /transl_table=11 FT /gene="ML2068" FT /product="possible membrane protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1841c" FT CDS 110146..112341 FT /transl_table=11 FT /gene="glcB" FT /gene_synonym="ML2069" FT /product="malate synthase" FT /note="Similar to Mycobacterium tuberculosis probable FT malate synthase g SW:MASZ_MYCTU (Q50596) fasta scores: E(): FT 0, 82.4% in 729 aa, and to Escherichia coli malate synthase FT g SW:MASZ_ECOLI () fasta scores: E(): 0, 56.9% in 731 aa." FT /db_xref="GOA:O32913" FT /db_xref="InterPro:IPR001465" FT /db_xref="InterPro:IPR006253" FT /db_xref="InterPro:IPR011076" FT /db_xref="UniProtKB/Swiss-Prot:O32913" FT /protein_id="CAC31024.1" FT /translation="MTDRVSAGNLRVARVLYDFVNNEALPGTDINPNSFWSGVAKVVAD FT LTPQNQSLLNSRDELQAQIDKWHRHRVIEPFDVDAYRQFLIDIGYLLPEPDDFTISTSG FT VDDEITMTAGPQLVVPVLNARFALNAANARWGSLYDALYGTDTIPETEGAEKGSEYNKI FT RGDKVIAYARKFMDQAVPLASDSWTNATGVSIFDGQLQIAIGTNSTGLASPEKFVGYNR FT QLRSSNWSVLLANHGLHIEVLIDPESPIGKTDPVGIKDVILESAITTIMDFEDSVTAVD FT ADDKVRGYRNWLGLNKGDLTEEVNKDGKTFTRVLNADRSYTTPDGGELTLPGRSLLFVR FT NVGHLTTSDAILVDGGDGQEKEVFEGIIDAVFTGLAAIHGLKTGEANGPLTNSRTGSIY FT IVKPKMHGPAEVAFTCELFSRVEDVLGLPQGTLKVGIMDEERRTTLNLKACIKAAADRV FT VFINTGFLDRTGDEIHTSMEAGPMIRKGAMKNSTWIKAYEDANVDIGLAAGFKGKAQIG FT KGMWAMTELMADMVEQKIGQPKAGATTAWVPSPTAATLHAMHYHQVDVAAVQQELTGQR FT RATVDQLLTIPLAKKLAWAPEEIREEVDNDCQSILGYVVRWVDQGIGCSKVPDIHNVAL FT MEDRATLRISSQLLANWLRHGVITSEDVRASLERMAPLVDQQNAEDPAYRPMAPNFDDS FT IAFLAAQELILSGAQQPNGYTEPILHRRRREFKAQNR" FT CDS 112467..114668 FT /transl_table=11 FT /gene="ML2070" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 69.7 kda protein Rv1836c SW:YI36_MYCTU (Q50597) fasta FT scores: E(): 0, 66.0% in 714 aa." FT /db_xref="InterPro:IPR002035" FT /db_xref="UniProtKB/TrEMBL:Q9CBE8" FT /protein_id="CAC31025.1" FT /translation="MTKLGAEFKPDQTRINRKAANTGMGRHSMPDPEDSIDQPSNQFAA FT SGPDQSDEIDHGYQSRMGYPEPVFEPAATGSPSYRSYPHGAEHPADSTPEALDETIDYQ FT SYWAEDRNEDLFVDGAADDHPDFPPRPAGSSTSSQAPTSLSHLFKASHRSVGKWQGGHR FT SDGGRRGVSIGVIATLVAVVVLVGAVIMWSFLGHILNNRKHQAAARCVGGHQTVAVVAD FT PSIADYLQEFAQSYNASARPVGDHCMMVTVKPVGSEAALTGFNDSWPANLGDKPALWIP FT GSSISAARLAVTADQKTISESHSLVTSPVLLAVRPEFEQALANKGWAALPGLQTNPNSL FT ADLNLPAWGSLRLALPMNGNSDATFLAGEAVATASVPAGAPAIQGVGAVRTLMSAQPKL FT ADSTWAEAMSTLLKPGDVATAPVHAVITTEQQLFQRGQSLSDAKSALGSWLPHGPAPVA FT DYPAVLLNGSWLTQEQAAAASEFARFVQKPDQLAKLAKAGFRVNGVTPPSSSVTSFAAV FT PSTVSVGDDGMRATLVEEMIQPSSGVAATIMLDQSMPTDEGGKTRLANVVAALDDKINA FT MPPTSVMGLWTFDGHKGQTEVTTGQLADPVNGQPRSAALTAALDKQYSSNGGAVSFTTL FT RMIYQEMLANYHVGQTNSVLVITAGPHTDQTLDGARLQDFIRTSADPAKPIAVNVIDFG FT TDPDQATWKAVAQISGGSYQNLSTSASLDLATAINTFLS" FT CDS 114694..115496 FT /pseudo FT /transl_table=11 FT /gene="ML2071" FT /product="similar to 1,3,4,6-tetrachloro-1,4-cyclohexadien FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1833c (Best blastx score 229)" FT CDS complement(115569..118427) FT /transl_table=11 FT /gene="gcvB" FT /gene_synonym="ML2072" FT /product="glycine decarboxylase" FT /note="Similar to Mycobacterium tuberculosis probable FT glycine dehydrogenase [decarboxylating] SW:GCSP_MYCTU FT (Q50601) fasta scores: E(): 0, 84.7% in 942 aa, and to FT Escherichia coli glycine dehydrogenase [decarboxylating] FT SW:GCSP_ECOLI (P33195) fasta scores: E(): 0, 53.5% in 956 FT aa." FT /db_xref="GOA:O32915" FT /db_xref="InterPro:IPR003437" FT /db_xref="InterPro:IPR015421" FT /db_xref="InterPro:IPR015424" FT /db_xref="InterPro:IPR020580" FT /db_xref="InterPro:IPR020581" FT /db_xref="UniProtKB/Swiss-Prot:O32915" FT /protein_id="CAC31027.1" FT /translation="MSVPNSSNKQTCFTARHIGPNSEDVATMLAVIGVESLDDLAAKAV FT PSDILDNVTDTGVAPGLDRLPPPATESETLAELGALARANTVAVSMIGQGYYDTLTPAV FT LSRNILENPAWYTPYTPYQPEISQGRLEALLNFQTLVSDLTGLEIANASMLDEGTAAAE FT AMTLMYRAARSTASRVVVDVDVFAQTVAVFATRAKPLGIDIVVADLREGLPDGEFFGVI FT TQLPGASGRITDWTALIAQAHSRGALVAVGADLLALTLITPPGEIGADVAFGTTQRFGV FT PMGFGGPHAGYLALHTKHARQLPGRLVGVSVDSDGTPAYRLALQTREQHIRRDKATSNI FT CTAQVLLAVMAAMYASYHGAEGLTGIARRVHAQARALAAGLSAAGVEVVHQAFFDTVLA FT RVPGRTVQIQGAAKERGINVWLVDGDHVSVACDEATTDEHITAVLAAFAATPARASFAG FT PDIATRTSAFLTHPTFTKYRTETSMMRYLRALADKDIALDRSMIPLGSCTMKLNAAAEM FT ESITWQEFTRQHPFAPVSDTPGLRRLISDLESWLVQITGYDAVSLQPNAGSQGEYAGLL FT AIHDYHVSRGEPHRNVCLIPSSAHGTNAASAALVGMRVVVVGCHDNGDVDLDDLRIKLS FT EHANRLSVLMITYPSTHGVYEHDIAEICAAVHDAGGQVYVDGANLNALVGLARPGKFGG FT DVSHLNLHKTFCIPHGGGGPGVGPVAVRSHLVSFLPGHPFAPELPQGQPVSSAPYGSAS FT LLPITWAYIRMMGADGLRTASLTAIASANYIARRLDKYFPVLYTGENGMVAHECILDLR FT PITKSVGVTVDDVAKRLADYGFHAPTMSFPVPGTLMVEPTESESLAEIDAFCEAMIAIR FT GEIARVGAGEWSVEDNPLRGAPHTAECLLASDWDHPYTREEAAYPLGKAFRPKVWPPVR FT RIDGVYGDRNLVCSCLPVEAFV" FT CDS complement(118595..119290) FT /transl_table=11 FT /gene="ML2073" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 24.0 kda protein Rv1830 SW:YI30_MYCTU (Q50603) fasta FT scores: E(): 0, 90.0% in 231 aa, and to Streptomyces FT coelicolor hypothetical 19.1 kda protein TR:CAB88877 FT (EMBL:AL353861) fasta scores: E(): 3.7e-30, 64.8% in 145 FT aa." FT /db_xref="GOA:O32916" FT /db_xref="InterPro:IPR000551" FT /db_xref="InterPro:IPR009061" FT /db_xref="UniProtKB/TrEMBL:O32916" FT /protein_id="CAC31028.1" FT /translation="MTHLVTRARSARGNTVSEQPRQGQLDLADYRDTPTATTHGDIGLN FT GPTAVSGPAQPGLFPDDSVPDELVGYRGPSACQIAGITYRQLDYWARTSLVVPSIRGAA FT GSGSQRLYSFKDILVLKIVKRLLDTGISLHNIRVAVDHLRQRGVQDLANITLFSDGTTV FT YECTSAEEVVDLLQGGQGVFGIAVSGAMRELTGVIDDFRGERADGGESIAAPEDELASR FT RKHRDRKIG" FT CDS complement(119523..120017) FT /transl_table=11 FT /gene="ML2074" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 18.1 kda protein Rv1829 SW:YI29_MYCTU (Q50604) fasta FT scores: E(): 0, 95.1% in 164 aa, and to Streptomyces FT coelicolor conserved hypothetical protein TR:CAB88878 FT (EMBL:AL353861) fasta scores: E(): 0, 60.9% in 161 aa." FT /db_xref="InterPro:IPR003729" FT /db_xref="UniProtKB/TrEMBL:O32917" FT /protein_id="CAC31029.1" FT /translation="MGEVRVVGIRVEQPQNQPVLLLREANGDRYLPIWIGQSEAAAIAL FT EQQGIEPPRPLTHDLIRDVIAALGHSLKEVRIVDLQEGTFYADLIFDRNIKVSARPSDS FT VAIALRVGVPIYVEDVVLAQAGLLIPDENDEEVGGAVREDEVEKFKEFLDSVSPDDFKA FT T" FT CDS complement(120134..120889) FT /transl_table=11 FT /gene="ML2075" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 26.4 kda protein Rv1828 SW:YI28_MYCTU (Q50605) fasta FT scores: E(): 0, 87.6% in 251 aa, and to Streptomyces FT coelicolor hypothetical 26.5 kda protein TR:CAB88879 FT (EMBL:AL353861) fasta scores: E(): 1.1e-14, 41.4% in 237 FT aa." FT /db_xref="GOA:O32918" FT /db_xref="InterPro:IPR000551" FT /db_xref="InterPro:IPR009061" FT /db_xref="UniProtKB/TrEMBL:O32918" FT /protein_id="CAC31030.1" FT /translation="MSAPDSPALVGMSIGAVLDLLRSDFPDVTISKIRFLEAEGLVTPQ FT RSASGYRRFTAYDCARLRFILTAQRDHYLPLKVIRAQLDAQPDGELPSFGSPYVAPRLF FT SVTGGPGAGVGSGVGSDIPAVSPAGVRLSREDLLDRSGVADDLLTALLKAGVITTGPGG FT FFDEHAIVILQCARALSEYGVEPRHLRAFRSAADRQSDLIVQIAGPIVKAGKAGARDRA FT DDLAREVAALAITLHTSLIKSAVRGVLHR" FT CDS complement(120886..121374) FT /transl_table=11 FT /gene="ML2076" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 17.3 kda protein Rv1827 SW:YI27_MYCTU (Q50606) fasta FT scores: E(): 0, 87.0% in 161 aa, and to Streptomyces FT coelicolor hypothetical 28.1 kda protein TR:CAB88880 FT (EMBL:AL353861) fasta scores: E(): 1.9e-25, 54.6% in 141 FT aa. Contains Pfam match to entry PF00498 FHA, FHA domain." FT /db_xref="HSSP:1MZK" FT /db_xref="InterPro:IPR000253" FT /db_xref="InterPro:IPR008984" FT /db_xref="UniProtKB/TrEMBL:O32919" FT /protein_id="CAC31031.1" FT /translation="MTDMDSGRQEDQTSDEVTVETTSVFRADFLNELDAPAQAGAESVV FT SGVEGLLAGSALLVVKRGPNAGSRFLLDQAITSAGRHPDSDIFLDDVTVSRRHAEFRLE FT GNEFHVVDVGSLNGTYVNREPVDSAVLANGDEVQIGKFRLVFLIGSKQDDDTGRTAGK" FT misc_feature complement(120955..121146) FT /note="Pfam match to entry PF00498 FHA, FHA domain, score FT 83.90, E-value 3.2e-21" FT CDS complement(121618..122016) FT /transl_table=11 FT /gene="gcvH" FT /gene_synonym="ML2077" FT /product="glycine cleavage system H protein" FT /note="Similar to Mycobacterium tuberculosis probable FT glycine cleavage system H protein SW:GCSH_MYCTU (Q50607) FT fasta scores: E(): 0, 78.4% in 134 aa, and to Escherichia FT coli glycine cleavage system H protein SW:GCSH_ECOLI FT (P23884) fasta scores: E(): 1.5e-22, 49.6% in 129 aa. FT Contains Pfam match to entry PF01597 GCV_H, Glycine FT cleavage H-protein. Contains PS00017 ATP/GTP-binding site FT motif A (P-loop). Contains PS00189 2-oxo acid FT dehydrogenases acyltransferase component lipoyl binding FT site." FT /db_xref="GOA:O32920" FT /db_xref="InterPro:IPR002930" FT /db_xref="InterPro:IPR003016" FT /db_xref="InterPro:IPR011053" FT /db_xref="InterPro:IPR017453" FT /db_xref="UniProtKB/Swiss-Prot:O32920" FT /protein_id="CAC31032.1" FT /translation="MSDIPSDLHYTAEHEWIRRSREDTVRVGLTDFAQSTLGDVVFVQL FT PEVGAELAAGKSFGEVESTKSVSDLYAPVSGTVSAVNTDLEGSPQLVNSDPYGAGWLLD FT VHVSDVGALESAIATLLDAETYRGTLTK" FT misc_feature complement(121627..122010) FT /note="Pfam match to entry PF01597 GCV_H, Glycine cleavage FT H-protein, score 180.80, E-value 2.3e-50" FT misc_feature complement(121783..121872) FT /note="PS00189 2-oxo acid dehydrogenases acyltransferase FT component lipoyl binding site" FT misc_feature complement(121846..121869) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(122044..122735) FT /pseudo FT /transl_table=11 FT /gene="ML2078" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1825 (Best blastx score 286)" FT CDS complement(122901..123225) FT /pseudo FT /transl_table=11 FT /gene="ML2079" FT /product="small basic protein similar SBP_BACSU FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1824 (Best blastx score 359)" FT CDS complement(123308..124234) FT /pseudo FT /transl_table=11 FT /gene="ML2080" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1823 (Best blastx score 305)" FT CDS complement(124237..124857) FT /transl_table=11 FT /gene="pgsA2" FT /gene_synonym="ML2081" FT /product="CDP-diacylglycerol-glycerol-3-phosphate" FT /note="Similar to Mycobacterium tuberculosis putative FT CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl- FT transferase SW:PGSA_MYCTU (Q50611) fasta scores: E(): 0, FT 76.6% in 205 aa, and to Escherichia coli FT CDP-diacylglycerol--glycerol-3-phosphate FT 3-phosphatidyltransferase SW:PGSA_ECOLI (P06978) fasta FT scores: E(): 4.5e-11, 30.5% in 177 aa. Contains Pfam match FT to entry PF01066 CDP-OH_P_transf, CDP-alcohol FT phosphatidyltransferase. Contains PS00379 CDP-alcohol FT phosphatidyltransferases signature." FT /note="Similar to and ML0979" FT /db_xref="GOA:O32921" FT /db_xref="InterPro:IPR000462" FT /db_xref="InterPro:IPR004570" FT /db_xref="UniProtKB/TrEMBL:O32921" FT /protein_id="CAC31036.1" FT /translation="MESVCPPNRVLTVPNLLSAVRLALIPAFVYVLLVMHADGWAVVIL FT VFSGVSDWADGKIARLLDQYSRLGVLLDPAVDRLYMVTIPVVLALSGIVPWWFVVALLA FT RDVLLTATLPLLWSRGLLSLPVTYIGKAATFSLMVGFPFVLLGTWDTLWSRVLGACGWA FT FLIWGTYAYLWAFVLYVVQMTMVVRWMPKIKHQAHRQFAGKAR" FT misc_feature complement(124282..124734) FT /note="Pfam match to entry PF01066 CDP-OH_P_transf, FT CDP-alcohol phosphatidyltransferase, score 169.60, E-value FT 5.4e-47" FT misc_feature complement(124627..124695) FT /note="PS00379 CDP-alcohol phosphatidyltransferases FT signature" FT CDS complement(124919..127255) FT /transl_table=11 FT /gene="secA2" FT /gene_synonym="ML2082" FT /product="SecA, preprotein translocase subunit" FT /note="Similar to Mycobacterium tuberculosis preprotein FT translocase secA 2 subunit SW:SEA2_MYCTU (Q50612) fasta FT scores: E(): 0, 87.0% in 782 aa, and to Bacillus subtilis FT preprotein translocase secA subunit SW:SECA_BACSU (P28366) FT fasta scores: E(): 0, 39.9% in 671 aa. Contains Pfam match FT to entry PF01043 SecA_protein, SecA protein, amino terminal FT region. Contains PS01312 Protein secA signatures." FT /note="Similar to and ML0779" FT /db_xref="GOA:O32922" FT /db_xref="InterPro:IPR000185" FT /db_xref="InterPro:IPR011115" FT /db_xref="InterPro:IPR011116" FT /db_xref="InterPro:IPR011130" FT /db_xref="InterPro:IPR014018" FT /db_xref="UniProtKB/Swiss-Prot:O32922" FT /protein_id="CAC31037.1" FT /translation="MSKTPRTQPGRLSSRFWRLLGASTDKNLNYSSAEVTAAAAYHKEA FT ADLGDEQLRKACGLLNLNDLADSRDVPQFLAIVREASERSTGLRPFDVQLLGALRMLAG FT DVIEMATGEGKTLAGAIAAAGYALAGRHVHVVTINDYLARRDAEWMGPLLEAIGLTVGW FT ITAESTREDRKAAYGCDVTYASVNEIGFDVLRDQLVTDVDDLVSPHPDVALIDEADSVL FT VDEALVPLVLAGATHRETPRLEIIKLVGELSAESDYDTDSDSRNVHLTDVGARKVEKAL FT GGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYIVRDDAVHLVNASRGRIAQLQRWPD FT GLQAAVEAKEGIETTETGEVLDTITVQALINRYATVCGMTGTALAAGEQLRQFYKLGVS FT PIPPNTPNIRDDASDRVYITAAAKNDAIVAHLAEVHETGQPVLVGTRNVAESEELHERL FT LRHGVPAVVLNAKNDAEEARFIAEAGKFGAVTVSTQMAGRGTDIRLGGSDESDHDRVVE FT LGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVIAANLDRNKLPMQTD FT EDGRIISLKTTGLLDHAQRVAEGRLLDVHANTWRYNQLIAQQRAIIVDRRNALLSSATA FT REELAELAPKRYEELAQALPKEEAEERLETICRLIMLYHLDRGWADHLAYLADIRESIH FT LRALGRQSPLDEFHRLAVNAFALLAADAIEAAQQTFETANILDGAPGLDLSKLARPTST FT WTYMVNDAPLSDDTLSPLSLPGVFR" FT misc_feature complement(125744..125791) FT /note="PS01312 Protein secA signatures" FT misc_feature complement(125975..127210) FT /note="Pfam match to entry PF01043 SecA_protein, SecA FT protein, amino terminal region, score 791.90, E-value FT 1.2e-260" FT CDS complement(127363..129009) FT /transl_table=11 FT /gene="ilvG" FT /gene_synonym="ML2083" FT /product="acetolactate synthase II" FT /note="Similar to Mycobacterium tuberculosis probable FT acetolactate synthase SW:ILVG_MYCTU (Q50613) fasta scores: FT E(): 0, 86.1% in 548 aa, and to Bacillus subtilis FT acetolactate synthase large subunit SW:ILVB_BACSU (P37251; FT P94564) fasta scores: E(): 1.2e-32, 28.5% in 543 aa. FT Contains Pfam match to entry PF00205 TPP_enzymes, Thiamine FT pyrophosphate enzymes. Contains PS00187 Thiamine FT pyrophosphate enzymes signature." FT /note="Similar to ML1696, ML2167 and ML0354" FT /db_xref="GOA:O32923" FT /db_xref="HSSP:1OZH" FT /db_xref="InterPro:IPR000399" FT /db_xref="InterPro:IPR011766" FT /db_xref="InterPro:IPR012000" FT /db_xref="InterPro:IPR012001" FT /db_xref="UniProtKB/TrEMBL:O32923" FT /protein_id="CAC31038.1" FT /translation="MSTDPVLTHSIHAGRLVVRRLKASGVDTVFTLSGGHLFSIYDGCR FT SESIRLIDTRHEQTAAFAAEGWSKVTRQPGVAVLTAGPGVTNGMSAMAAAQQNQSPLVV FT LGGRAPALRWGMGSLQEIDHVPFVAPLARFAATAQSADAAGRLVDEALQAAVVAPSGVG FT FVDFPMDYVFSMADDVGGGPGALANLPVAPAANPEALDRAAGLLAAAHRPVIMAGTNVW FT WGHAEAALLRLAEECQIPVLMNGMARGVVPADHPLAFSRARGKALGEADVALVVGVPMD FT FRLGFGKVFGSQTQLVVADRAEPDRDYPRPVAAGLYGDLPAILSALAGVGGTDSQDWIR FT ALRTAETATRDLEKAELDDDRLPLHPMRVYAELASLLDRDAIVVIDAGDFGSYAGRVID FT SYLPGCWLDSGPFGCLGSGPGYALAAKLARPNRQVVLLQGDGAFGFSGMEWDTLVRHNV FT PVVSVIGNNGIWGLEKHPMEALYGYSVVAELRPGTRYDEVVRALGGHGELVSVPGELRP FT ALERAFVTGLPSVVNVLTDPSVAYPRRSNLA" FT misc_feature complement(127411..128949) FT /note="Pfam match to entry PF00205 TPP_enzymes, Thiamine FT pyrophosphate enzymes, score 254.00, E-value 2.4e-78" FT misc_feature complement(127684..127743) FT /note="PS00187 Thiamine pyrophosphate enzymes signature" FT CDS 129103..131019 FT /transl_table=11 FT /gene="ML2084" FT /product="probable multidrug resistance pump" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT ABC transporter ATP-binding protein Rv1819c SW:YI19_MYCTU FT (Q50614) fasta scores: E(): 0, 74.9% in 634 aa, and in FT C-term to Escherichia coli hypothetical ABC transporter FT ATP-binding protein in pqql-hipa intergenic region FT SW:YDDA_ECOLI (P31826; P76133; P76876) fasta scores: E(): FT 0, 29.9% in 551 aa. Contains Pfam match to entry PF00005 FT ABC_tran, ABC transporter. Contains PS00017 ATP/GTP-binding FT site motif A (P-loop). Contains PS00211 ABC transporters FT family signature." FT /note="Similar to ML1089, ML1424, ML0848 and ML0590" FT /db_xref="GOA:O32924" FT /db_xref="InterPro:IPR003439" FT /db_xref="InterPro:IPR003593" FT /db_xref="InterPro:IPR010509" FT /db_xref="InterPro:IPR011527" FT /db_xref="InterPro:IPR017871" FT /db_xref="InterPro:IPR017940" FT /db_xref="UniProtKB/TrEMBL:O32924" FT /protein_id="CAC31039.1" FT /translation="MELRPFYPSVNWGYALPDSLWWIAKAWAISAACVVVLVMLSFITR FT WGRQYWRITRGYFIGPQSVGVWLMLAVLLFSVVISVRLNVLFSYQSKDLYNALQAAFEG FT AGAQNDLVKQSGMHGFWMSLGIFSILAVIFIARVMADIYLTQRFIIAWRMWLTNHLTTD FT WLDQRAYYREQFIDNTIDNPDQRIQQDIDIFTAGAGGTPNGPSNGTGSTLLFGAVESVI FT SVISFTAILWNLSGRLAVFEFEIPRAMFWIVIVYVLLATIITFWIGRPLIGLNFANEKL FT NAAFRYALVRLRDAAEAVAFYRGEEAERKQLEQRFTPIIDNYRRYVSRTIRFLGWNASV FT SQTIVPLPWILQAPRLFAGKINLGDVGQTATAFGNIHDSLSFFRNNYAAFAAFRAAIIR FT LHGLVVANARSRELPHVTAKSTNDGTVHVVAVEVRTSAGEQLIDPLDLQLNCGSSLVIT FT GRSGVGKTTMLRSLAELWPYASGTLSRPDGKNETMFLSQLPYVPLGNLRGVVCYPNAPA FT DIPEDTVRDTLTKVALNPLCDRLDEERDWAKILSPGEQQRIAFARILLTKPKAIFLDES FT TSALDEGLEFALYQMLRSELPDCIIVSVSHRRAVELLHAQQLELLGGGQWRLGPVEKEP FT LHV" FT misc_feature 130456..130974 FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 79.00, E-value 9.9e-20" FT misc_feature 130477..130500 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 130750..130794 FT /note="PS00211 ABC transporters family signature" FT repeat_region 131157..131302 FT /note="146 bp sequence found at 5'-end of copies 6 and 7 of FT LEPREP" FT repeat_region 131303..133685 FT /note="Dispersed repeat, LEPREP, copy 7" FT CDS 131648..131787 FT /pseudo FT /transl_table=11 FT /gene="ML2085" FT /note="Similar to Pseudomonas putida transposase tnpa1 FT TR:Q9R9U9 (EMBL:AJ245436) (355 aa) fasta scores: E(): FT 3.4e-05, 47.8% id in 46 aa, and to Agrobacterium FT tumefaciens transposase TR:Q44454 (EMBL:Z18270) (366 aa) FT fasta scores: E(): 0.00026, 41.3% id in 46 aa" FT CDS 131992..133135 FT /pseudo FT /transl_table=11 FT /gene="ML2086" FT /product="putative group II intron maturase-related FT protein" FT /note="Similar to many e.g. Cryphonectria parasitica FT (Chesnut blight fungus) putative maturase TR:AAF27656 FT (EMBL:AF218567) (778 aa) fasta scores: E(): 7.8e-11, 29.2% FT id in 216 aa" FT stem_loop 132619..132672 FT CDS 133400..133498 FT /pseudo FT /transl_table=11 FT /gene="ML2087" FT /note="Similar to Agrobacterium tumefaciens transposase FT TR:Q44454 (EMBL:Z18270) (366 aa) fasta scores: E(): 0.0002, FT 51.5% id in 33 aa, and to Pseudomonas putida transposase FT tnpa1 TR:Q9R9U9 (EMBL:AJ245436) (355 aa) fasta scores: E(): FT 0.00088, 48.5% id in 33 aa" FT repeat_region 133686..133702 FT /note="17 bp sequence found at 3'-end of copies 2, 3, 4 and FT 8 of LEPREP. NB in the other copies this sequence is 21 bp FT long" FT CDS complement(133694..134998) FT /transl_table=11 FT /gene="ML2088" FT /product="putative cytochrome p450" FT /note="Similar to Streptomyces coelicolor putative FT cytochrome p-450 hydroxylase TR:Q9X8Q3 (EMBL:AL049754) FT fasta scores: E(): 0, 37.4% in 401 aa, and to Mycobacterium FT tuberculosis putative cytochrome p450 rv1880c SW:YI80_MYCTU FT (O08464) fasta scores: E(): 0, 38.0% in 416 aa, and to FT Bacillus subtilis biotin biosynthesis; cytochrome p450-like FT enzyme SW:BIOI_BACSU (P53554) fasta scores: E(): 0, 37.1% FT in 383 aa. Contains Pfam match to entry PF00067 p450, FT Cytochrome P450." FT /db_xref="GOA:Q9CBE7" FT /db_xref="HSSP:1UED" FT /db_xref="InterPro:IPR001128" FT /db_xref="InterPro:IPR002397" FT /db_xref="InterPro:IPR017973" FT /db_xref="UniProtKB/TrEMBL:Q9CBE7" FT /protein_id="CAC31043.1" FT /translation="MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPG FT TRADPFPVYRALIDYGPMQLPGMPLTVFSSFSDCDEALRHPLSASDRLKATLAQQAIAA FT GAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGDIAALVDSLLDKGAAAGQ FT FDVIADLAFPLAVAVICRLLGVPYEDAPEFGRVSALLVQSVDPFITITGEPPEATEERL FT RAGVWLRDYLEQLVKCRRGTPGEDLISRLIELDESGDQLTEEEIIATCGLLLVAGHETT FT VNLIANAVLAMLRNPSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQTT FT LTEGDTMVLLLAAANRDPAVYSRPDEFDPDRPSSRHLAFAVGSHFCLGAALARLEATVT FT LSAISARFPQVQLAGELVYKPNVAMRGMSALPVQV" FT misc_feature complement(133760..134647) FT /note="Pfam match to entry PF00067 p450, Cytochrome P450, FT score 218.30, E-value 1.1e-61" FT CDS complement(135494..137441) FT /pseudo FT /transl_table=11 FT /gene="ML2089" FT /product="probable dehydrase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0939 (Best blastx score 341)" FT CDS complement(137441..139500) FT /pseudo FT /transl_table=11 FT /gene="ML2090" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0938 (Best blastx score 431)" FT CDS 139859..140044 FT /transl_table=11 FT /gene="ML2091" FT /product="hypothetical protein" FT /note="no database matches." FT /db_xref="UniProtKB/TrEMBL:Q9CBE6" FT /protein_id="CAC31046.1" FT /translation="MNRPDLVDIWTGDRCGEQGALALCLAGKARVDIRNFRVVDTVCTS FT DEFMVRLLDGLWGYGL" FT CDS 140374..141006 FT /pseudo FT /transl_table=11 FT /gene="ML2092" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0937c (Best blastx score 333)" FT CDS complement(141281..142195) FT /transl_table=11 FT /gene="pstA1" FT /gene_synonym="ML2093" FT /product="membrane-bound component of phosphate transport" FT /note="Similar to Mycobacterium tuberculosis phosphate FT transport system permease protein pstc2 TR:O86344 FT (EMBL:Z47983) fasta scores: E(): 0, 83.0% in 317 aa, and to FT Escherichia coli phosphate transport system permease FT protein pstc SW:PSTC_ECOLI (P07653) fasta scores: E(): FT 1.7e-30, 33.9% in 304 aa. Contains Pfam match to entry FT PF00528 BPD_transp, Binding-protein-dependent transport FT systems inner membrane component." FT /db_xref="GOA:Q50097" FT /db_xref="InterPro:IPR000515" FT /db_xref="InterPro:IPR005672" FT /db_xref="UniProtKB/Swiss-Prot:Q50097" FT /protein_id="CAC31048.1" FT /translation="MNLDTLDRPVKAVVLRPISVRRRIKNNVATMFFFTSFLIALVPLV FT WLLSVVVARGFYAVTRFDWWTHSLRGVMPEEFAGGVYHALYGSLVQAVVAAIMAVPLGS FT MTAVYLVEYGSGPFVRVTTFMVDVLAGVPSIVAALFIFCLWIATLGFQQSAFAVSLALV FT LLMLPVVVRSTEEILRLVPDELREACYALGIPKWKTIVRIVFPIATPGIISGVLLSIAR FT VIGETAPVLVLVGYSRSINFDIFDGNMASLPLLIYTELTNPEYAGFLRVWGAALTLIIL FT VAGINLFGAAFRFLATRRCSGCR" FT misc_feature complement(141413..141667) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 60.70, E-value 3.1e-14" FT CDS complement(142213..143172) FT /transl_table=11 FT /gene="pstC2" FT /gene_synonym="ML2094" FT /product="membrane-bound component of phosphate transport" FT /note="Similar to Mycobacterium tuberculosis phosphate FT transport system permease protein pstc2 TR:O86344 FT (EMBL:Z47983) fasta scores: E(): 0, 83.0% in 317 aa, and to FT Escherichia coli phosphate transport system permease FT protein pstc SW:PSTC_ECOLI (P07653) fasta scores: E(): FT 1.7e-30, 33.9% in 304 aa. Contains Pfam match to entry FT PF00528 BPD_transp, Binding-protein-dependent transport FT systems inner membrane component. Contains PS00402 FT Binding-protein-dependent transport systems inner membrane FT comp sign.." FT /db_xref="GOA:Q50098" FT /db_xref="InterPro:IPR000515" FT /db_xref="InterPro:IPR011864" FT /db_xref="UniProtKB/Swiss-Prot:Q50098" FT /protein_id="CAC31049.1" FT /translation="MIKPTPAAVGSYVTRRCDRLFKSAAAAAGSTVVAAILLIAIFLLL FT RAVPSLRANHANFFTSAKFDTTGDKNLAFGIRDLFMVTVLSSICALVLAVPVAIGIAVF FT LTQYVPARLSRLFSAMVDLLAAVPSIIFGLWGVFVLAPKLQPIAVFLNHNLGWLFLFKQ FT GNVSLAGGGTIFTSGIVLAVMILPIVTSVSREVFRHTPLIQIEAAQALGATKWEVVQMT FT VLPFGRSGVAAAAMLGLGRALGETLAVLIILRSAARSGNWSLFDGGYTFASKIASAASE FT FSQPLPTGAYIAAGFALFFLTFVVNAVARAISGGRVNG" FT misc_feature complement(142354..142587) FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 25.80, E-value 0.001" FT misc_feature complement(142498..142584) FT /note="PS00402 Binding-protein-dependent transport systems FT inner membrane comp sign." FT CDS complement(143215..144324) FT /transl_table=11 FT /gene="phoS2" FT /gene_synonym="ML2095" FT /product="PstS component of phosphate uptake" FT /note="Similar to Mycobacterium tuberculosis FT phosphate-binding protein 3 precursor TR:O86343 FT (EMBL:Z95209) fasta scores: E(): 0, 77.3% in 370 aa, and to FT Escherichia coli phosphate-binding periplasmic protein FT precursor SW:PSTS_ECOLI (P06128; P76744) fasta scores: E(): FT 4.4e-22, 31.2% in 333 aa. Contains Pfam match to entry FT PF01449 PstS, Phosphate-binding protein. Contains PS00013 FT Prokaryotic membrane lipoprotein lipid attachment site." FT /db_xref="GOA:Q9CBE5" FT /db_xref="InterPro:IPR005673" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBE5" FT /protein_id="CAC31050.1" FT /translation="MKLNQFGAAIGLLATGALLSGCGSDNNAAVGSARTGPSSGQVSCG FT GKPTLKASGSTAQANAMTRFVNAFERSCPGQTLNYTANGSGAGVSEFNGNQTDFGGSDS FT PLSRKEYAAAEQRCGSQAWNLPVVFGPIAITYNVNGLSSLNLDGPTTAKIFNGSIASWN FT DPAIQALNTGVALPAEPIHVVFRNDESGTTDNFQRYLDVASNGEWGKGIGKTFKGGVGE FT GAKGNDGTSAAVKSTEGSITYNEWSFASARKLNTAKIATSADPEPIAISVDSVGKTISG FT ATIIGEGNDLVLDTVSFYKPAQPGSYPIVLATYEIVCSKYPDAQVGRAVKAFLQSTIGG FT GQNGLGDNGYVPIPDSFKSRLSTAANAIA" FT misc_feature complement(143323..144189) FT /note="Pfam match to entry PF01449 PstS, Phosphate-binding FT protein, score 416.50, E-value 2.5e-121" FT misc_feature complement(144259..144291) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS 144666..145440 FT /pseudo FT /transl_table=11 FT /gene="ML2096" FT /product="short-chain alcohol dehydrogenase family FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0927c (Best blastx score 352)" FT CDS 145468..146549 FT /pseudo FT /transl_table=11 FT /gene="ML2097" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0926c (Best blastx score 224)" FT CDS 146652..147932 FT /transl_table=11 FT /gene="mntH" FT /gene_synonym="ML2098" FT /product="probable manganese transport protein" FT /note="Similar to Mycobacterium tuberculosis probable FT manganese transport protein mntH SW:MNTH_MYCTU (O05916) FT fasta scores: E(): 0, 74.8% in 413 aa, and to Bacillus FT subtilis probable manganese transport protein mntH FT SW:MNTH_BACSU (P96593) fasta scores: E(): 0, 44.1% in 415 FT aa, and to Salmonella typhimurium manganese transport FT protein mnth SW:MNTH_SALTY (Q9RPF4) fasta scores: E(): 0, FT 43.1% in 406 aa. Contains Pfam match to entry PF01566 FT Nramp, Natural resistance-associated macrophage protein." FT /db_xref="GOA:Q50103" FT /db_xref="InterPro:IPR001046" FT /db_xref="UniProtKB/Swiss-Prot:Q50103" FT /protein_id="CAC31053.1" FT /translation="MFVNLTCLSEGNGSRGKALAESTQAELKTSWYLLGPAFVAAIAYV FT DPGNVAANVSSGAQFGYLQLWVVVVANVLAGLVQYLSAKLGLVTGQSLPQAISKQMSHP FT FRLGFWLQAELVAMATDVAEIVGGAIAFHILFRVSLLLGGVITGTVSLLLLMVKDRRGQ FT LLFERVITGLLFVIVVGFTSSFFVATPSPEDMVNGLLPRFQGTESVLLAAAIIGATVMP FT HAVYLHSGLALDRHGHPHAGRSRRRLLRVTRLDVILAMTIAGIVNTAMLLVAAINLQHH FT QVTAYIEGTYTAIQDTLGATIAMLFAIGLLASSLASASVGAYAGALIMQGLLQRSIPML FT IRRLITLCPAIAILALGFDPTRALVLSQIVLSFGIPFAVLPLVKLTNNRGLMGNDTNHP FT ATTVLGWAVAILVSLLNVVLIYLTVTS" FT misc_feature 146799..147848 FT /note="Pfam match to entry PF01566 Nramp, Natural FT resistance-associated macrophage protein, score 630.00, FT E-value 1.4e-185" FT CDS complement(148022..148996) FT /pseudo FT /transl_table=11 FT /gene="nrdZ" FT /gene_synonym="ML2099" FT /product="ribonucleotide reductase, class II (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT nrdZ (Best blastx score 274)" FT CDS complement(149070..149290) FT /pseudo FT /transl_table=11 FT /gene="ML2100" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv2302 (Best blastx score 68)" FT CDS 149760..150050 FT /pseudo FT /transl_table=11 FT /gene="ML2101" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv2028c (Best blastx score 91)" FT CDS 150835..151983 FT /pseudo FT /transl_table=11 FT /gene="lipL" FT /gene_synonym="ML2102" FT /product="esterase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog lipL FT (Best blastx score 311)" FT CDS complement(152922..153688) FT /pseudo FT /transl_table=11 FT /gene="ML2103" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2631 (Best blastx score 259)" FT CDS complement(153817..154149) FT /pseudo FT /transl_table=11 FT /gene="ML2104" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2630 (Best blastx score 180)" FT repeat_region complement(154156..154577) FT /note="422 bp repeat, 100% identical to region FT 2504357..2504778" FT CDS complement(154557..155290) FT /pseudo FT /transl_table=11 FT /gene="ML2105" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0574c (Best blastx score 197)" FT CDS 155518..156785 FT /pseudo FT /transl_table=11 FT /gene="ML2106" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0571c (Best blastx score 879)" FT misc_feature 155521..156057 FT /note="Pfam match to entry PF00156 Pribosyltran, FT Phosphoribosyl transferase domain, score 12.50, E-value FT 0.0027" FT repeat_region complement(156507..156928) FT /note="422 bp repeat, 100% identical to region FT 2502006..2502427" FT tRNA 158751..158823 FT /gene="argT" FT /note="tRNA Arg anticodon CCT, Cove score 73.39" FT CDS complement(159255..159581) FT /pseudo FT /transl_table=11 FT /gene="ML2107" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0919 (Best blastx score 197)" FT CDS complement(159676..159970) FT /pseudo FT /transl_table=11 FT /gene="ML2108" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0918 (Best blastx score 147)" FT CDS 162095..163007 FT /pseudo FT /transl_table=11 FT /gene="ML2109" FT /product="lipid transfer protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0914c (Best blastx score 322)" FT CDS 163012..164482 FT /pseudo FT /transl_table=11 FT /gene="ML2110" FT /product="probable dioxygenase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0913c (Best blastx score 498)" FT CDS complement(164689..165123) FT /transl_table=11 FT /gene="ML2111" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 15.4 kda protein TR:O05904 (EMBL:Z95210) fasta scores: E(): FT 0, 69.5% in 141 aa." FT /db_xref="UniProtKB/TrEMBL:Q50121" FT /protein_id="CAC31066.1" FT /translation="MIHRLRLGWLVAFFATIVLISVWIPWLTTKVNDEGWANAIGGTHG FT NLELPSGFGAGQLIVLLSSTLLVAGAMMGRGLSVKVASIAALIISLLIVVIVVWYYQLN FT VNPPVVAECGLYLGAAGAVCAMVCSVWAVIAAVAAGRSSL" FT CDS complement(165222..165950) FT /pseudo FT /transl_table=11 FT /gene="ML2112" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0911 (Best blastx score 142)" FT CDS complement(166020..166565) FT /transl_table=11 FT /gene="ML2113" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 15.8 kda protein TR:O05902 (EMBL:Z95210) fasta scores: E(): FT 0, 83.9% in 143 aa, and to Mycobacterium tuberculosis FT hypothetical 15.3 kda protein Rv1546 SW:YF46_MYCTU (Q10780) FT fasta scores: E(): 1e-19, 38.0% in 142 aa." FT /db_xref="InterPro:IPR019587" FT /db_xref="UniProtKB/TrEMBL:Q50123" FT /protein_id="CAC31068.1" FT /translation="MTSRIKRMAKLTGSIDVPLPPNEAWMCASDLARFGEWLTIHRAWR FT SKLPEVVEKGTVIESYVEVKGMPNRIRWTVVRYKAPEAMTLNGDGVGGVKVKLIAKVSP FT KDDGSVVSFDVHLGGSALFGPIGMIVAVALRTDIRESLQNFVTAFSRPEPGLIRSRALV FT VDQHSRAVVEQRSASAGL" FT CDS complement(166562..166732) FT /transl_table=11 FT /gene="ML2114" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 6.4 kda protein TR:O05901 (EMBL:Z95210) fasta scores: E(): FT 1.8e-07, 61.9% in 42 aa, and to Streptomyces coelicolor FT hypothetical 9.9 kda protein TR:O69965 (EMBL:AL022268) FT fasta scores: E(): 0.038, 41.3% in 46 aa." FT /db_xref="UniProtKB/TrEMBL:Q9CBE3" FT /protein_id="CAC31069.1" FT /translation="MLDKAKDILVQNADKVETVLDKAGEFVDEKAKGKYTDTIYQVAEE FT TKKAASFDTFG" FT CDS complement(166880..168851) FT /pseudo FT /transl_table=11 FT /gene="ctpE" FT /gene_synonym="ML2115" FT /product="probable cation transport ATPase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT ctpE (Best blastx score 568)" FT CDS complement(168848..169710) FT /pseudo FT /transl_table=11 FT /gene="ML2116" FT /product="probable penicillin binding protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0907 (Best blastx score 178)" FT CDS complement(169802..170786) FT /pseudo FT /transl_table=11 FT /gene="ML2117" FT /product="probable membrane protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0906 (Best blastx score 599)" FT CDS complement(170920..171663) FT /transl_table=11 FT /gene="echA6" FT /gene_synonym="ML2118" FT /product="enoyl-CoA hydratase/isomerase superfamily member" FT /note="Similar to Mycobacterium tuberculosis probable FT enoyl-coa hydratase echa6 SW:ECH6_MYCTU (Q10533) fasta FT scores: E(): 0, 85.8% in 247 aa, and to Escherichia coli FT probable enoyl-coa hydratase paaf SW:PAAF_ECOLI (P76082; FT P78288; O53014) fasta scores: E(): 3.1e-18, 32.1% in 252 FT aa. Contains Pfam match to entry PF00378 ECH, Enoyl-CoA FT hydratase/isomerase family." FT /db_xref="GOA:Q50130" FT /db_xref="InterPro:IPR001753" FT /db_xref="InterPro:IPR018376" FT /db_xref="UniProtKB/Swiss-Prot:Q50130" FT /protein_id="CAC31073.1" FT /translation="MIGITQAEGVMTIELQRPERRNALNSQLIEKLREAVQKASSADSE FT VSTRVIVLTGQGTVFCAGADLSGDAFAADYPDRLIELHRVMDAVPMPVIGAINGPAIGA FT GLQLAMQCDLRVVAPDAYFQFPTSKYGLALDNWSIRRLSSLVGHGRARAMLLTAEKLTA FT DIALQTGMANRIGALADAQAWAAEVTGLAPLAIQHAKRVLNDDGSIEEAWPEHKKLFDK FT AWTSQDVIEAQVARVEKRPPKFQGA" FT misc_feature complement(171133..171633) FT /note="Pfam match to entry PF00378 ECH, Enoyl-CoA FT hydratase/isomerase family, score 104.70, E-value 1.8e-27" FT CDS 171690..173005 FT /pseudo FT /transl_table=11 FT /gene="accD3" FT /gene_synonym="ML2119" FT /product="acetyl/propionyl CoA carboxylase [beta] subunit FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT accD3 (Best blastx score 1142)" FT CDS 173170..173517 FT /pseudo FT /transl_table=11 FT /gene="ML2120" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv1482c (Best blastx score 90)" FT CDS complement(173690..174100) FT /transl_table=11 FT /gene="ML2121" FT /product="conserved hypothetical protein" FT /note="Similar to Streptomyces coelicolor putative FT tetr-family regulator SC5F8.13 TR:CAB93741 (EMBL:AL357613) FT fasta scores: E(): 4.6e-12, 48.5% in 97 aa." FT /db_xref="UniProtKB/TrEMBL:O33072" FT /protein_id="CAC31076.1" FT /translation="MYGGRLHPRGVLLAVRSPRGIVLRALRPARDHNHRTAQPAIAGAG FT ESADLVELVDRVAATLLLDPDWLLVKTDFLMHAGCHPDLIQCLVAQRAKLRVAIEDRFS FT SAIELPNAIGTMGNAACVVVAAYDGVSIQPAR" FT CDS 174346..175947 FT /pseudo FT /transl_table=11 FT /gene="ML2122" FT /product="putative dehydrogenase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv0785 (Best blastx score 219)" FT CDS 176300..177001 FT /transl_table=11 FT /gene="ML2123" FT /product="two-component response regulator" FT /note="Similar to Mycobacterium tuberculosis probable FT transcriptional activator protein cy31.31c TR:Q10531 FT (EMBL:Z73101) fasta scores: E(): 0, 95.7% in 233 aa, and to FT Pseudomonas syringae transcriptional activator protein copr FT SW:COPR_PSESM (Q02540) fasta scores: E(): 2.5e-32, 43.6% in FT 225 aa. Contains Pfam match to entry PF00486 trans_reg_C, FT Transcriptional regulatory protein, C terminal. Contains FT Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain." FT /db_xref="GOA:Q50136" FT /db_xref="InterPro:IPR001789" FT /db_xref="InterPro:IPR001867" FT /db_xref="InterPro:IPR011006" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/Swiss-Prot:Q50136" FT /protein_id="CAC31078.1" FT /translation="MDTGVSSPRVLVVDDDSDVLASLERGLRLSGFEVSTAIDGAEALR FT NATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADD FT YLVKPFVLAELVARVKALLRRRGATATSSSETIAVGPLEVDIPGRRARVNGVDVDLTKR FT EFDLLAVLAEHKTTVLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEANSGPRLLHT FT VRGVGFVLRMQ" FT misc_feature 176321..176656 FT /note="Pfam match to entry PF00072 response_reg, Response FT regulator receiver domain, score 131.40, E-value 1.6e-35" FT misc_feature 176765..176980 FT /note="Pfam match to entry PF00486 trans_reg_C, FT Transcriptional regulatory protein, C terminal, score FT 107.00, E-value 1.1e-30" FT CDS 177019..178359 FT /transl_table=11 FT /gene="ML2124" FT /product="sensor histidine kinase" FT /note="Similar to Mycobacterium tuberculosis probable FT sensor-like histidine kinase rv0902c SW:Y902_MYCTU (Q10560) FT fasta scores: E(): 0, 92.4% in 446 aa, and to Escherichia FT coli sensor protein cpxa SW:CPXA_ECOLI (P08336) fasta FT scores: E(): 7e-14, 28.9% in 301 aa. Contains Pfam match to FT entry PF00672 DUF5, Domain found in bacterial signal FT proteins. Contains Pfam match to entry PF00512 signal, FT Histidine kinase." FT /db_xref="GOA:O33071" FT /db_xref="InterPro:IPR003594" FT /db_xref="InterPro:IPR003660" FT /db_xref="InterPro:IPR003661" FT /db_xref="InterPro:IPR004358" FT /db_xref="InterPro:IPR005467" FT /db_xref="InterPro:IPR009082" FT /db_xref="UniProtKB/Swiss-Prot:O33071" FT /protein_id="CAC31079.1" FT /translation="MNILSRIFARTPSLRTRVVVATAIGAAIPVLIVGTVVWVGITNDR FT KERLDRKLDEAAGFAIPFVPRGLDEIPRSPNDQDAIITVRRGNLVKSNFDITLPKLTND FT YADTYLRGVRYRVRTVEIPAPEPTSIAVGATYDATVAETNNLHRRVLLICGFAIAAAAV FT FAWLLAAFAVRPFKQLAQQTRSVDAGGEAPRVEVHGATEAVEIAEAMRGMLQRIWNEQN FT RTKEALASARDFAAVSSHELRTPLTAMRTNLEVLATLDLADDQRKEVLGDVIRTQSRIE FT ATLSALERLAQGELSTSDDHVPVDITELLDRAAHDATRSYPELKVSLVPSPTCIIVGLP FT AGLRLAVDNAVANAVKHGGATRVQLSAVSSRAGVEIAVDDNGSGVPEDERQVVFERFSR FT GSTASHSGSGLGLALVAQQAQLHGGTASLETSPLGGARLLLRISAPS" FT misc_feature 177466..177675 FT /note="Pfam match to entry PF00672 DUF5, Domain found in FT bacterial signal proteins, score 51.60, E-value 1.7e-11" FT misc_feature 177736..178347 FT /note="Pfam match to entry PF00512 signal, Histidine FT kinase, score 106.50, E-value 5e-28" FT CDS complement(178387..178773) FT /pseudo FT /transl_table=11 FT /gene="ML2125" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0901 (Best blastx score 154)" FT CDS complement(178960..179932) FT /pseudo FT /transl_table=11 FT /gene="ompA" FT /gene_synonym="ML2126" FT /product="member of OmpA family (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT ompA (Best blastx score 201)" FT CDS 180219..181566 FT /pseudo FT /transl_table=11 FT /gene="ML2127" FT /product="possible oxidoreductase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0897c (Best blastx score 236)" FT CDS complement(181577..182694) FT /pseudo FT /transl_table=11 FT /gene="PPE" FT /gene_synonym="ML2128" FT /product="PPE-family protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog PPE FT (Best blastx score 182)" FT CDS complement(182837..182998) FT /transl_table=11 FT /gene="ML2129" FT /product="PE-family protein (pseudogene)" FT /note="Similar to Mycobacterium tuberculosis PE-family FT protein TR:O53690 (EMBL:AL021930) fasta scores: E(): FT 1.6e-05, 60.7% in 56 aa." FT /protein_id="CAC31084.1" FT /translation="MVTLCVLPEGLAAAGAAVQAPPARLVAAHVAAASVVSSAADLVSV FT QTAVQFSA" FT CDS complement(183764..185059) FT /transl_table=11 FT /gene="gltA2" FT /gene_synonym="ML2130" FT /product="citrate synthase 1" FT /note="Similar to Mycobacterium tuberculosis citrate FT synthase 1 SW:CISY_MYCTU (Q10530) fasta scores: E(): 0, FT 91.0% in 431 aa, and to Corynebacterium glutamicum citrate FT synthase SW:CISY_CORGL (P42457) fasta scores: E(): 0, 62.7% FT in 432 aa. Contains Pfam match to entry PF00285 FT citrate_synt, Citrate synthase. Contains PS00480 Citrate FT synthase signature." FT /db_xref="GOA:O33066" FT /db_xref="HSSP:1K3P" FT /db_xref="InterPro:IPR002020" FT /db_xref="InterPro:IPR010953" FT /db_xref="InterPro:IPR016141" FT /db_xref="InterPro:IPR016142" FT /db_xref="InterPro:IPR019810" FT /db_xref="UniProtKB/TrEMBL:O33066" FT /protein_id="CAC31085.1" FT /translation="MADTDDTVTLKYPGGEIDLQIVRATEGNDGIAIVPVLAKTGYTTF FT DVGYGNTASTKSSITYIDGDAGILRYRGYPIEQLAEKSTFIEVCYLLIYGELPATDQLA FT EFTHRIQRHTMLHEDLKRFYDGFPRNAHPMPVLSSVVNALSAYYQDALDPMDNGQVELS FT TIRLLAKLPTIAAYAYKKSVGQPFLYPDNAFSLVENFLRMTFGLPAEPYEPDPEVVRAL FT DMLFILHADHEQNCSTSTVRLVGSSRANLFTSISGGINALWGPLHGGANQAVLEMLEGI FT RESGDDVGGFVQKVKNCQAGVKLMGFGHRVYKNYDPRARIVKEQADKILVKLGGDDDLL FT NIAKGLEEAALTDDYFIERKLYPNVDFYTGLIYRALGFPTRMFTVLFALGRLPGWIAHW FT REMHDEGDSKIGRPRQIYTGYTERDYTAIETR" FT misc_feature complement(183821..184918) FT /note="Pfam match to entry PF00285 citrate_synt, Citrate FT synthase, score 640.50, E-value 4.6e-201" FT misc_feature complement(184106..184144) FT /note="PS00480 Citrate synthase signature" FT CDS complement(185308..185928) FT /transl_table=11 FT /gene="pdxH" FT /gene_synonym="ML2131" FT /product="pyridoxamine 5'-phosphate oxidase" FT /note="Similar to Mycobacterium tuberculosis pyridoxamine FT 5'-phosphate oxidase SW:PDXH_MYCTU (O06207) fasta scores: FT E(): 0, 69.3% in 205 aa, and to Escherichia coli FT pyridoxamine 5'-phosphate oxidase SW:PDXH_ECOLI (P28225) FT fasta scores: E(): 9.8e-27, 43.3% in 171 aa. Contains Pfam FT match to entry PF01243 Pyridox_oxidase, Pyridoxamine FT 5'-phosphate oxidase. Contains PS01064 Pyridoxamine FT 5'-phosphate oxidase signature." FT /db_xref="GOA:O33065" FT /db_xref="InterPro:IPR000659" FT /db_xref="InterPro:IPR009002" FT /db_xref="InterPro:IPR011576" FT /db_xref="InterPro:IPR012349" FT /db_xref="InterPro:IPR019576" FT /db_xref="InterPro:IPR019740" FT /db_xref="UniProtKB/Swiss-Prot:O33065" FT /protein_id="CAC31086.1" FT /translation="MEYGSVEKDGSPDLDTDWLYDGWLTLFCKWIDDAERAGVAEPNAM FT VLATVANGRPVSRSVLCKGADEAGIIFFTNYDSDKGDDLAATPYASVTFPWYQLGRQVH FT IRGPVSTVDPQVSEDYWSKRPRGSQLGAWASHQSRPIASRTALLDQLLEVTVRFADSEL FT IPLPPNWGGYLIVPEVVEFWQGRENRVHNRIRVTGGCIERLQP" FT misc_feature complement(185311..185928) FT /note="Pfam match to entry PF01243 Pyridox_oxidase, FT Pyridoxamine 5'-phosphate oxidase, score 198.40, E-value FT 1.1e-55" FT misc_feature complement(185350..185391) FT /note="PS01064 Pyridoxamine 5'-phosphate oxidase signature" FT CDS 186106..187151 FT /pseudo FT /transl_table=11 FT /gene="citA" FT /gene_synonym="ML2132" FT /product="citrate synthase 2 (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT citA (Best blastx score 650)" FT CDS 187502..187940 FT /pseudo FT /transl_table=11 FT /gene="ML2133" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0887c (Best blastx score 221)" FT CDS complement(187963..189630) FT /transl_table=11 FT /gene="fprB" FT /gene_synonym="ML2134" FT /product="ferredoxin, ferredoxin-NADP reductase" FT /note="Similar to Mycobacterium tuberculosis probable FT ferredoxin/ferredoxin--NADP reductase SW:FPRB_MYCTU FT (Q10547) fasta scores: E(): 0, 76.6% in 560 aa, and to Homo FT sapiens NADPH:adrenodoxin oxidoreductase precursor FT SW:ADRO_HUMAN (P22570; Q13716) fasta scores: E(): 2.9e-30, FT 37.4% in 484 aa. Contains 2 Pfam matches to entry PF00037 FT fer4, 4Fe-4S binding domain. Contains PS00198 4Fe-4S FT ferredoxins." FT /db_xref="GOA:O33064" FT /db_xref="InterPro:IPR000759" FT /db_xref="InterPro:IPR001450" FT /db_xref="InterPro:IPR013027" FT /db_xref="InterPro:IPR016040" FT /db_xref="InterPro:IPR017896" FT /db_xref="InterPro:IPR017900" FT /db_xref="UniProtKB/Swiss-Prot:O33064" FT /protein_id="CAC31089.1" FT /translation="MPYIITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPVA FT CVDCGACVSACPVGAIASDTRLAPKQLPFIEINASYYPARPIDLKLPPTSKLAPVIPAA FT QVHVRRRPLTVAIVGSGPAAMYAADELLTQPGVWVNVFEKLPTPYGLVRAGLAPDHQNT FT KKVTELFDRVAEHRRFRFFLNVEIGRHLSHDELLAHHHAVLYAVGAPDDRRLNIDGMGI FT PGTGTATELVAWINAHPDFAYLPVDLSHERVVVIGNGNVALDVARLLTADPDNLARTDI FT SEFALHVLGGSAVREVVVAARRGPAHSAFTLPELIGLKATSEVVLDAGDRKLVEGDFAT FT VSDSLTRKKLEVLSSLVDSSKPTSRRRIRLAYQLTPKRVLGNQRATGVEFSVTGTEESR FT RFDAGLVLTSVGYRGKRIRDLPFDEEAAVIPNDGGRVVDPSRGRPMPGAYVAGWIKRGP FT TGFIGTNKLCSVQTVQAVVADFNAGWLTDPVAEPAELAKLVHARQPDTVDSVGWRAIDA FT AEIAQGSTEGRPRRKFTDVADMLAVAAGAPPLRLRALS" FT misc_feature complement(189445..189516) FT /note="Pfam match to entry PF00037 fer4, 4Fe-4S binding FT domain, score 34.60, E-value 2.2e-06" FT misc_feature complement(189460..189495) FT /note="PS00198 4Fe-4S ferredoxins" FT misc_feature complement(189556..189627) FT /note="Pfam match to entry PF00037 fer4, 4Fe-4S binding FT domain, score 19.30, E-value 0.0026" FT CDS complement(189646..190671) FT /transl_table=11 FT /gene="ML2135" FT /product="possible transmembrane protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 39.8 kda protein rv0885 SW:Y885_MYCTU (Q10546) fasta FT scores: E(): 0, 83.9% in 341 aa, and to Streptomyces FT coelicolor putative membrane protein TR:Q9XAE8 FT (EMBL:AL079356) fasta scores: E(): 1.5e-13, 27.1% in 255 FT aa. Contains possible membrane spanning hydrophobic FT domains." FT /db_xref="GOA:O33063" FT /db_xref="UniProtKB/TrEMBL:O33063" FT /protein_id="CAC31090.1" FT /translation="MARTRMVRRWRNNMEVRDDTDYVGMLTTLSEGSVRRNFNPYTDID FT WESPAFAVKDNDPRWILPDTDPLGRHPWYLAQPEQRKIEIGMWRQANVAKVGLHFESIL FT VRGLMNYTFWMPNGSPEYRYCLHECVEECNHTMMFQEMVNRVGADVPGMPRRLRWLSPL FT VPLVAGPLPVAFFIGVLAGEEPIDHMQKNVLREGKSLHPIMERVMAIHVAEEARHISFA FT HEFLRKRLTHLTKRQLFWVSLYYPLTMRVLCNAIMVPPKAFWQEFNIPREVKKELFFRS FT PESRKLLRDIFADVRMLAYDTRLMETRSARLMWHICKIDGQPSRYRGEPQRQHPATTSA FT A" FT CDS 190885..192015 FT /transl_table=11 FT /gene="serC" FT /gene_synonym="ML2136" FT /product="putative phosphoserine aminotransferase" FT /note="Similar to Mycobacterium tuberculosis putative FT phosphoserine aminotransferase SW:SERC_MYCTU (Q10534) fasta FT scores: E(): 0, 87.5% in 376 aa, and to Methanosarcina FT barkeri phosphoserine aminotransferase SW:SERC_METBA FT (P52878) fasta scores: E(): 4.5e-12, 24.7% in 369 aa." FT /db_xref="GOA:O33062" FT /db_xref="InterPro:IPR000192" FT /db_xref="InterPro:IPR006272" FT /db_xref="InterPro:IPR015421" FT /db_xref="InterPro:IPR015424" FT /db_xref="UniProtKB/Swiss-Prot:O33062" FT /protein_id="CAC31091.1" FT /translation="MADQLTPSLDIPAALKPRDGRFGSGPSKVRPEQLQALTNTAATLF FT GTSHRQAPVKNLVGRVRAGLAELFSLPDGYQVILGNGGATAFWDAAAFGLIDKRSLHLT FT YGEFSSKFASAVAKNPFIDEPIVIKSDPGSAPKPTGDPSVDVIAWAHNETSTGVAVPVR FT RPTGSGGALIAIDATSGAGGLPVDIAQTDAYYFAPQKNFASDGGLWLAIMSPAALARVD FT SITASGRWVPDFLSLPIAVENSLKNQTYNTPAICTLALLAEQLDWLLGNGGLEWAVKRT FT ADSSQRLYAWAEDRPYTTPFVVDPALRSQVVGTIDFTDDVDAAAVAKILRANGIIDTEP FT YRKLGRNQLRVAMFPAVEPDDVRALTECVDWIVERL" FT CDS 192133..192888 FT /transl_table=11 FT /gene="ML2137" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 27.4 kda protein rv0883c SW:Y883_MYCTU (Q10545) fasta FT scores: E(): 0, 79.4% in 253 aa, and to Streptomyces FT coelicolor hypothetical 39.0 kda protein TR:O50529 FT (EMBL:AL009204) fasta scores: E(): 2.2e-19, 36.0% in 247 FT aa." FT /db_xref="UniProtKB/TrEMBL:O33061" FT /protein_id="CAC31092.1" FT /translation="MRELKVVGLDPDSKTILCEGDIPGERFKLPADDRLRAAVRGDTTL FT LDQPQLDIQVTNMLSPKEIQARIRAGASVEQVAMASGSDIARIRRFAHPVLLERSRAAE FT LATAAHPVLADGPAVLTLLETVSAALVKRGLEPDKLSWDAWRNEDSRWTVQLMWHAGRS FT DNLAHFCFTPGAHGGTVTASDDAANELIDPDFNRPLRPLARVAHLDFVEPATPATVTPD FT NQLVSSRRGKPTIPAWEDVLLGVRSAGQR" FT CDS complement(192991..193188) FT /pseudo FT /transl_table=11 FT /gene="ML2138" FT /product="unknown hydrophobic protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0882 (Best blastx score 124)" FT CDS complement(193300..194099) FT /pseudo FT /transl_table=11 FT /gene="ML2139" FT /product="possible rRNA methyltransferase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0881 (Best blastx score 255)" FT CDS complement(194135..194566) FT /transl_table=11 FT /gene="ML2140" FT /product="putative MarR-family protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 15.6 kda protein Rv0880 SW:Y880_MYCTU (Q10542) fasta FT scores: E(): 0, 90.2% in 143 aa, and to Streptomyces FT coelicolor putative marR-family protein TR:CAB93410 FT (EMBL:AL357524) fasta scores: E(): 1.6e-13, 39.6% in 134 FT aa. Contains Pfam match to entry PF01047 MarR, MarR FT family." FT /note="Similar to ML2696 and ML0550" FT /db_xref="GOA:O33060" FT /db_xref="InterPro:IPR000835" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/Swiss-Prot:O33060" FT /protein_id="CAC31095.1" FT /translation="MLDSDARLASDLSLAVMRLARQLRFRNPQSPVSLSQLSALTTLAN FT EGAMTPGALAIRERVRPPSMTRVIASLADMGFVDREPHPVDGRQVLVSVSQSGAELVKA FT ARRARQEWLVERLMTLNSDKRDILRNAADLILELIDESP" FT misc_feature complement(194162..194473) FT /note="Pfam match to entry PF01047 MarR, MarR family, score FT 109.80, E-value 5.1e-29" FT CDS 194770..195045 FT /transl_table=11 FT /gene="ML2141" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 9.5 kda protein Rv0879c SW:Y879_MYCTU (Q10541) fasta FT scores: E(): 6.6e-25, 76.9% in 91 aa." FT /db_xref="InterPro:IPR019681" FT /db_xref="UniProtKB/TrEMBL:O33059" FT /protein_id="CAC31096.1" FT /translation="MLVEPDRSREPPPLPSMLLEVWPVIMVGALAWLIAVVAAFVVSSL FT QSWRPVALAGLVVGLFGTGIFVWQLAAARRGARGAQGGLETYLDPR" FT CDS complement(195157..195966) FT /transl_table=11 FT /gene="ML2142" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 27.5 kda protein rv0877 SW:Y877_MYCTU (Q10539) fasta FT scores: E(): 0, 80.5% in 257 aa, and to Streptomyces FT coelicolor hypothetical 32.2 kda protein TR:CAB93404 FT (EMBL:AL357524) fasta scores: E(): 2.5e-19, 43.3% in 270 FT aa." FT /db_xref="UniProtKB/TrEMBL:O33058" FT /protein_id="CAC31097.1" FT /translation="MTGPVEDSAVATVAEWPEELAAVLTNAADDARAAIEEFSGSVTVG FT DYLGVGYEDPNAATHRFLAHLPGYQGWQWAVVVAAYPGAEHATVSEVVLVPGPTALLAP FT EWVPWEQRVRPGDLGPGDLLAPTSEDLRLVPGYNASGDPAVDEIAAEIGLGRRWVMSVW FT GRSAAAERWHGGDYGPDSPMARSTKRVCRDCGFFLSLVGSLGAMFGVCGNEMSADGHVV FT DKLYGCGAHSDTPAPAGSGSSVYEPYDDGVLDILEPSTVQLPESPAD" FT CDS 196076..197815 FT /transl_table=11 FT /gene="ML2143" FT /product="possible membrane protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 57.9 kda protein rv0876c SW:Y876_MYCTU (Q10564) fasta FT scores: E(): 0, 81.2% in 568 aa, and to Streptomyces FT coelicolor putative integral membrane protein TR:CAB93403 FT (EMBL:AL357524) fasta scores: E(): 5.3e-16, 38.8% in 448 FT aa. Contains possible membrane spanning hydrophobic FT domains." FT /db_xref="GOA:O33057" FT /db_xref="InterPro:IPR016196" FT /db_xref="UniProtKB/Swiss-Prot:O33057" FT /protein_id="CAC31098.1" FT /translation="MSGRRRNHPGRLASIPGLRTRTGSRNQHPGIANYPADSSDFRPAQ FT QRRALEQREQQAGQLDPARRSPSMPSANRYLPPLGQQQSEPQHNSAPPCGPYPGERIKV FT TRAAAQRSREMGYRMYWMVQRAATADGADKSGLTALTWPVVTNFAVDSAMAVALANTLF FT FAAASGESKSKVALYLLITIAPFAVIAPLIGPALDRLQHGRRVALATSFVLRTGLATLL FT IMNYDGATGSYPSMVLYPCALAMMVLSKSFSVLRSAVTPRVMPPSIDLVRVNSRLTVFG FT LLGGTIAGGAIAAGVEFVCAHLFKLPGALFVVAAITISGALLSMRIPRWVEVTAGEIPA FT TLSYRLHRKPLRQSWPEEVKKVSGRLRQPLGRNIITSLWGNCTIKVMVGFLFLYPAFVA FT KEHQANGWVQLGMLGLIGTAAAIGNFAGNFTSARLQLGRPAVLVVRCTIAVTVLALAAS FT VAGNLLMTTIATLITSGSSAIAKASLDASLQNDLPEESRASGFGRSESTLQLAWVLGGA FT LGVMVYTDLWVGFTAVSALLILGLAQTVVSFRGDSLIPGLGGNRPVMIEQESMRRAAAV FT SPQ" FT CDS 197823..198311 FT /transl_table=11 FT /gene="ML2144" FT /product="possible exported protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 17.8 kda protein Rv0875c precursor SW:Y875_MYCTU (Q10537) FT fasta scores: E(): 0, 73.5% in 155 aa. Contains a possible FT N-terminal signal sequence." FT /db_xref="UniProtKB/TrEMBL:O33056" FT /protein_id="CAC31099.1" FT /translation="MQRRVTVLLPAVVMLLAAAAGFGVWLLVREPDPQRPEISVYSHGH FT LTRVGPYLHCNMLNLDECQTPQAQGVLSADEHNPVQLSVPETISRAPWRLLRIYEDPTG FT TTSTLYRPNTRLAVTIPTLDPHRGRLTGIVVQLLTLVVDPAGEVHDVPHTEWLVRLTF" FT CDS 199529..200828 FT /pseudo FT /transl_table=11 FT /gene="cycA" FT /gene_synonym="ML2145" FT /product="transport of D-alanine, D-serine and glycine FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog cycA FT (Best blastx score 255)" FT CDS complement(200973..202842) FT /pseudo FT /transl_table=11 FT /gene="fadE10" FT /gene_synonym="ML2146" FT /product="acyl-CoA dehydrogenase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT fadE10 (Best blastx score 502)" FT CDS complement(204161..204571) FT /transl_table=11 FT /gene="cspB" FT /gene_synonym="ML2147" FT /product="probable cold shock protein" FT /note="Similar to Mycobacterium tuberculosis cold shock FT protein b TR:O53883 (EMBL:AL022004) fasta scores: E(): 0, FT 86.0% in 136 aa, and to Bacillus cereus cold shock-like FT protein cspc SW:CSPC_BACCE (Q45098) fasta scores: E(): FT 5.2e-08, 54.4% in 57 aa. Contains Pfam match to entry FT PF00313 CSD, 'Cold-shock' DNA-binding domain." FT /note="Similar to and ML0198" FT /db_xref="GOA:O33052" FT /db_xref="HSSP:1MJC" FT /db_xref="InterPro:IPR002059" FT /db_xref="InterPro:IPR011129" FT /db_xref="InterPro:IPR012340" FT /db_xref="InterPro:IPR016027" FT /db_xref="UniProtKB/TrEMBL:O33052" FT /protein_id="CAC31102.1" FT /translation="MPTGKVKWYDADKGFGFLSQEDGEDVYVRSSALPAGVEGLKAGQR FT VEFGVASGRRGPQALSLKLIDPPPSFARQVRREALAEHRHSPDELHGMVEDMITLLEST FT VQPELRKGRYPDRKTARRVSEVVKAVAREFDA" FT misc_feature complement(204377..204571) FT /note="Pfam match to entry PF00313 CSD, 'Cold-shock' FT DNA-binding domain, score 86.90, E-value 4.8e-23" FT CDS 204745..205095 FT /pseudo FT /transl_table=11 FT /gene="ML2148" FT /product="unknown hydrophobic protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0870c (Best blastx score 300)" FT CDS 205254..206191 FT /pseudo FT /transl_table=11 FT /gene="moaA2" FT /gene_synonym="ML2149" FT /product="molybdenum cofactor biosynthesis, protein A FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT moaA2 (Best blastx score 272)" FT CDS 206211..206464 FT /pseudo FT /transl_table=11 FT /gene="moaD2" FT /gene_synonym="ML2150" FT /product="molybdopterin converting factor subunit 1 FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT moaD2 (Best blastx score 134)" FT CDS 206895..207419 FT /transl_table=11 FT /gene="ML2151" FT /product="conserved hypothetical protein" FT /note="Similar to C-terminus of Mycobacterium tuberculosis FT hypothetical 40.0 kda protein TR:O53879 (EMBL:AL022004) FT fasta scores: E(): 4.8e-29, 63.0% in 200 aa. Contains FT N-terminal signal sequence." FT /note="Similar to ML0240 and ML2030" FT /db_xref="GOA:O33049" FT /db_xref="InterPro:IPR010618" FT /db_xref="UniProtKB/TrEMBL:O33049" FT /protein_id="CAC31106.1" FT /translation="MSESYRKLTTSSIIVAKITFTGAMLDGSIALAGQASPATDSEWDQ FT VARCESGGNWSINTGNGYLGGLQFSQGTWASHGGGEYAPSAQLATREQQIAVAERVLAT FT QGSGAWPACGHGLSGPSLQEVLPAGMGAPWINGAPAPLAPPPPAEPAPPQPPADNFPPT FT PGDVPSPLARP" FT CDS complement(207566..207894) FT /pseudo FT /transl_table=11 FT /gene="moaE2" FT /gene_synonym="ML2152" FT /product="molybdopterin-converting factor subunit 2 FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT moaE2 (Best blastx score 146)" FT CDS complement(207903..208291) FT /pseudo FT /transl_table=11 FT /gene="mog" FT /gene_synonym="ML2153" FT /product="molybdopterin biosynthesis (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT mog (Best blastx score 218)" FT CDS complement(208316..208708) FT /pseudo FT /transl_table=11 FT /gene="moaC2" FT /gene_synonym="ML2154" FT /product="molybdenum cofactor biosynthesis, protein C FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT moaC2 (Best blastx score 177)" FT CDS complement(208866..209090) FT /transl_table=11 FT /gene="ML2155" FT /product="hypothetical 10.1 kda protein" FT /product="conserved hypothetical protein" FT /note="Similar to C-terminus of Mycobacterium tuberculosis FT hypothetical 10.1 kda protein TR:O53875 (EMBL:AL022004) FT fasta scores: E(): 1.5e-21, 74.0% in 73 aa." FT /db_xref="UniProtKB/TrEMBL:Q9CBE2" FT /protein_id="CAC31110.1" FT /translation="MKSVNYYVVADIAKSKAHKSRYVDNGWPTTDPDHHAVSELVTDCA FT GALSPFGDLVFPVPADDLPYVHPVTVVNR" FT CDS 209188..211449 FT /transl_table=11 FT /gene="ML2156" FT /product="possible DNA-binding protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 79.7 kda protein TR:O53874 (EMBL:AL022004) fasta scores: FT E(): 0, 77.6% in 753 aa, and to Streptomyces coelicolor FT hypothetical 90.4 kda protein TR:CAB93395 (EMBL:AL357524) FT fasta scores: E(): 3.9e-27, 34.6% in 856 aa. Contains a FT probable helix-turn-helix motif at aa 277-298 (Score 1075, FT SD +2.85)" FT /db_xref="GOA:Q9CBE1" FT /db_xref="UniProtKB/TrEMBL:Q9CBE1" FT /protein_id="CAC31111.1" FT /translation="MTDNTPDIPLGSWLADLSDERLIQLLELRPDLAQPPPGSIAALAA FT RAQARQSIKAATDELNFLQFAVIDALLVLQADSTPVPTTKLKALIGDRAPQADVVSALD FT NLRQRALAWGETTVRIAAAAAAALPWHPGQVTLEDISSTGEQIAELIARLSQTQRDVLQ FT KLLEGSPLGRTRDAAPGAPPDRPVPQLLAMGLLRRIDADTVILPRRVGQVLRGEQSGPT FT QLTQPYPVVSVTTPNDADAEAAGAVIEALHELDVLLETLGSAPVYELRNGGLGVREFKR FT LAKATGINEPRLGLLLEVTAAAGLIASGIPDPEPATGDSPYWAPTVATDRFTAMPPAER FT WHLLASTWLDLQCRPALIGSRGPDAKSYGALSNSLYSTAAPLDRRLLLGMLAELPAGVG FT VEAAEASAALIWRRPRWARRLQPGPVADMLAEGHTMGLVGRGAISTPGRALLDEAIASA FT DPAIAVAAMTRALPEPIDHFLVQADLTVVVPGPLQRNLAKELGTVATVESAGTAMVYRI FT SEQSIRHALDIGKTRDWMHALFTNHSKTPVPQRLTYLINDVARRHGQLRIGMAASFVRC FT EDPALLTQTVAAAEELQLRALAPTVAVSPAPIAEVLVTLQSAGFAPAAEDSSGSIVDVR FT PRRARLPTPQHRRPYRPLQRPNLETLNAVIAVLRKVAATPFGGIRVDPTVTMSLLQRAT FT KEKTTLVIGYLDAAGIATQRMVSPIAIRGGQLVAFDPGTGRLRDFVIHRITSVVSSDSQ FT " FT CDS 211486..213135 FT /transl_table=11 FT /gene="ML2157" FT /product="probable DNA helicase" FT /note="Similar to Mycobacterium tuberculosis putative DNA FT helicase TR:O53873 (EMBL:AL022004) fasta scores: E(): 0, FT 91.1% in 542 aa, and to Saccharomyces cerevisiae DNA repair FT helicase RAD25 SW:RA25_YEAST (Q00578) fasta scores: E(): 0, FT 29.3% in 611 aa. Contains Pfam match to entry PF00271 FT helicase_C, Helicases conserved C-terminal domain." FT /db_xref="GOA:Q9CBE0" FT /db_xref="InterPro:IPR001161" FT /db_xref="InterPro:IPR001650" FT /db_xref="InterPro:IPR006935" FT /db_xref="InterPro:IPR014001" FT /db_xref="InterPro:IPR014021" FT /db_xref="UniProtKB/TrEMBL:Q9CBE0" FT /protein_id="CAC31112.1" FT /translation="MTDGPLIVQSDKTVLLEVNHKLADAARAAIAPFAELERAPEHVHT FT YRITPLALWNARAAGHDAEQVVDTLISHARYAVPQPLLVDIVDTMARYGRLQLVKNPAH FT GLTLVSLDRTVLEEVLHNKKIAPMVGGRIDDDTVVVHPSERGRIKQLLLKIGWPAEDLA FT GYVDGEAHPIILHQDGWQLRDYQRLAADSFWSGGSGVVVLPCGAGKTLVGAAAMAKTGA FT TTLILVTNIVVARQWKRELITHTSLTEDEIGEYSGERKEIRPVTISTYQMITHRTKGEY FT RHLELFNSRDWGLIIYDEVHLLPAPVFRMTADLQSKRRLGLTATLIREDGREGDVFSLI FT GPKRYDTPWKDLEEQGWIAPAKCVEVRVTLTNNERMTYATAEPEERYRVCSTAHSKIAV FT VKSVLSRHPGEQTLVIGAYLDQLNELGSELNAPIIQGSTRTKEREALFDAFRRGEVFTL FT VVSKVANFSIDLPEAAVAVQVSGTFGSRQEEAQRLGRLLRPKADGGGAIFYSVVARDSL FT DAEYAAHRQRFLAEQGYSYIIRDADDLLGPAI" FT misc_feature 212752..212985 FT /note="Pfam match to entry PF00271 helicase_C, Helicases FT conserved C-terminal domain, score 32.10, E-value 1.3e-05" FT CDS complement(213247..213639) FT /transl_table=11 FT /gene="ML2158" FT /product="hypothetical protein" FT /note="no database matches." FT /db_xref="UniProtKB/TrEMBL:Q9CBD9" FT /protein_id="CAC31113.1" FT /translation="MCSVASRFLRTRSLTQCMFCALNKGAFAVIVCLGDIAHKFTDKTV FT HVHVTEIRTRRYGAYEVHATFAPLVEDASPKRCTIAKAVYRGRQASDLRTSTSPSCRTS FT VPAPEVIQMDETVLCADGEQEKLASW" FT CDS complement(215082..215777) FT /pseudo FT /transl_table=11 FT /gene="ML2159" FT /product="possible cytochrome P450 (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv0764c (Best blastx score 82). See also ML0447" FT repeat_region 215086..215825 FT /note="740 bp repeat, 100% identical to region FT 547230..547967" FT CDS 220893..221212 FT /pseudo FT /transl_table=11 FT /gene="ML2160" FT /product="probable oxidoreductase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv1260 (Best blastx score 80)" FT CDS complement(221311..223455) FT /transl_table=11 FT /gene="fadB" FT /gene_synonym="ML2161" FT /product="putative fatty oxidation complex alpha subunit" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 76.1 kda protein TR:O53872 (EMBL:AL022004) fasta scores: FT E(): 0, 88.6% in 719 aa, and to Escherichia coli fatty FT oxidation complex alpha subunit SW:FADB_ECOLI (P21177) FT fasta scores: E(): 0, 33.0% in 684 aa. Contains Pfam match FT to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase. FT Contains Pfam match to entry PF00378 ECH, Enoyl-CoA FT hydratase/isomerase family." FT /note="Similar to ML1724, ML2402, ML2401, ML1241 and FT ML2118" FT /db_xref="GOA:Q9CBD8" FT /db_xref="HSSP:3HDH" FT /db_xref="InterPro:IPR001753" FT /db_xref="InterPro:IPR006108" FT /db_xref="InterPro:IPR006176" FT /db_xref="InterPro:IPR008927" FT /db_xref="InterPro:IPR013328" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9CBD8" FT /protein_id="CAC31116.1" FT /translation="MADTAIQWSKDADGIVTLTMNDPSRSANVMNEIYIESMGNAVDRI FT VAEKDSITGVVITSAKRTFFAGGDLTAMINTGSEEAGQCFDTVETVKKQLRTLETLGKP FT VVAAINGAALGGGLEIALACHHRIAADVKGSQLGLPEVTLGLLPGGGGVTRTVRMFGIQ FT NAFVNILSQGTRFKPAKAKEIGLVDELLSTVEELVPAAKAWIKANPEAHEQPWDKKSYE FT MPGGTPTSPGLAAILPSFPSLLRKQLKGAPMPAPRAILAAAVEGAQVDFDTASRIESRY FT FVSLVTGQVAKNMIQAFFLDLQHINSGGSRPDGIGKTPIKKIGVLGAGMMGAGIAYVSA FT KAGYNVVLKDVSLEAAQKGKSYSEKLEAKALERGRTTQEKSDVLLACIAPTGDPTDLKG FT VDFVIEAVFENQELKHKVFQEIEDIVDPNAVLGSNTSTLPITGLATGVKRQEDFIGIHF FT FSPVDKMPLVEIIKGEKTSDEALARVFDYALAIGKTPIVVNDSRGFFTSRVIGTFVNEA FT LAMLGEGVEPSSIEQAGAQAGYPAPPLQLSDELNLELMHKIAIATRKGVEDAGGMYESH FT PAETVVEKMIKLGRSGRLKGAGFYEYVDGKRSGLWLGLRETFKSGSSQPPLQDMIDRML FT FAEALETQKCLDENVLTSTADANIGSIMGIGFPPWTGGSAQFIAGYSGPAGTGQQAFVS FT RARELVAKYGDRFLPPESLL" FT misc_feature complement(221650..222489) FT /note="Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA FT dehydrogenase, score 297.50, E-value 1.7e-85" FT misc_feature complement(222880..223410) FT /note="Pfam match to entry PF00378 ECH, Enoyl-CoA FT hydratase/isomerase family, score 142.40, E-value 7.8e-39" FT CDS complement(223460..224671) FT /transl_table=11 FT /gene="fadA" FT /gene_synonym="ML2162" FT /product="putative beta-ketoadipyl CoA thiolase" FT /note="Similar to Mycobacterium tuberculosis putative FT beta-ketoadipyl CoA thiolase TR:O53871 (EMBL:AL022004) FT fasta scores: E(): 0, 94.5% in 403 aa, and to Escherichia FT coli acetyl-coa acetyltransferase TR:O53017 (EMBL:X97452) FT fasta scores: E(): 0, 44.1% in 422 aa, and to Acinetobacter FT calcoaceticus beta-ketoadipyl coa thiolase SW:PCAF_ACICA FT (Q43974) fasta scores: E(): 0, 40.9% in 425 aa. Contains FT Pfam match to entry PF00108 thiolase, Thiolase. Contains FT PS00017 ATP/GTP-binding site motif A (P-loop). Contains FT PS00098 Thiolases acyl-enzyme intermediate signature. FT Contains PS00099 Thiolases active site. Contains PS00737 FT Thiolases signature 2." FT /note="Similar to ML1158 and ML2564" FT /db_xref="GOA:Q9CBD7" FT /db_xref="HSSP:1AFW" FT /db_xref="InterPro:IPR002155" FT /db_xref="InterPro:IPR016038" FT /db_xref="InterPro:IPR016039" FT /db_xref="InterPro:IPR020610" FT /db_xref="InterPro:IPR020613" FT /db_xref="InterPro:IPR020615" FT /db_xref="InterPro:IPR020616" FT /db_xref="InterPro:IPR020617" FT /db_xref="UniProtKB/TrEMBL:Q9CBD7" FT /protein_id="CAC31117.1" FT /translation="MSEEAFIYEAIRTPRGKQKNGSLHEVKPVSLVVGLVEELRKRNPD FT LDENLISDVILGCVSPVGDQGGDIARATVLAAGLPVTAGGVQLNRFCASGLEAVNTAAQ FT KVRSGWDDLVLAGGVESMSRVPMGSDGGAMGLDPATNYDVMFVPQGIGADLIATIEGFS FT RDDVDVYALRSQEKAAAAWSGGYFAKSVVPVRDQNGLLILDHDEHMRPDTSKEGLAKLK FT PAFEGLAAMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSEAVGKSQGLT FT PRARMVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASVVLKFQKD FT LNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERCNARRALVTLCIGAGMGVATI FT IERV" FT misc_feature complement(223463..224668) FT /note="Pfam match to entry PF00108 thiolase, Thiolase, FT score 409.80, E-value 2.5e-119" FT misc_feature complement(223481..223522) FT /note="PS00099 Thiolases active site" FT misc_feature complement(223577..223627) FT /note="PS00737 Thiolases signature 2" FT misc_feature complement(223841..223864) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(224354..224410) FT /note="PS00098 Thiolases acyl-enzyme intermediate FT signature" FT CDS 224876..225907 FT /pseudo FT /transl_table=11 FT /gene="ML2163" FT /product="possible aminotransferase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0858c (Best blastx score 361)" FT CDS complement(226155..226418) FT /pseudo FT /transl_table=11 FT /gene="ML2164" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0857 (Best blastx score 152)" FT CDS complement(226604..227598) FT /pseudo FT /transl_table=11 FT /gene="far" FT /gene_synonym="ML2165" FT /product="fatty acyl-CoA racemase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT far (Best blastx score 434)" FT CDS complement(227838..228051) FT /pseudo FT /transl_table=11 FT /gene="ML2166" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0854)" FT CDS 228115..229824 FT /transl_table=11 FT /gene="pdc" FT /gene_synonym="ML2167" FT /product="pyruvate (or indolepyruvate) decarboxylase" FT /note="Similar to Mycobacterium tuberculosis putative FT pyruvate/indole-pyruvate carboxylase TR:O53865 FT (EMBL:AL022004) fasta scores: E(): 0, 79.2% in 543 aa, and FT to Enterobacter cloacae indole-3-pyruvate decarboxylase FT SW:DCIP_ENTCL (P23234) fasta scores: E(): 0, 47.8% in 550 FT aa, and to Saccharomyces cerevisiae pyruvate decarboxylase FT isozyme 3 SW:DCP3_YEAST (P26263) fasta scores: E(): 0, FT 38.1% in 557 aa. Contains Pfam match to entry PF00205 FT TPP_enzymes, Thiamine pyrophosphate enzymes. Contains FT PS00017 ATP/GTP-binding site motif A (P-loop). Contains FT PS00013 Prokaryotic membrane lipoprotein lipid attachment FT site." FT /note="Similar to ML1696 and ML2083" FT /db_xref="GOA:Q9CBD6" FT /db_xref="HSSP:1PVD" FT /db_xref="InterPro:IPR011766" FT /db_xref="InterPro:IPR012000" FT /db_xref="InterPro:IPR012001" FT /db_xref="InterPro:IPR012110" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBD6" FT /protein_id="CAC31122.1" FT /translation="MTAPKIEAVYTVGAYLLDRLAELGVTEIFGVPGDYTLEFLDHIVA FT HPTIRWVGNANELNAGYAADGYGRLRGISALVTTFGVGELSAANAIAGSYAEHVPVVHI FT VGAPPKDAQSTHRALHHSLGDGDFEHFIRISSEITCSQANLTTATACKEIDRVLSEVRK FT HKRPGYILLSTDVARFPTEPPAAPLPGHTDGTSPRALSLFIDAATKLIADKRMTVLADL FT LVHRLQVVKELETLLTADVVPYATLMWGKSLLDESSPNFLGIYAGAASTEAVRAAIEQA FT PVLVTAGVVFTDMVSGFFSQRIDPARTIDVGQYQSSVADKVFTPLEMGDALEALASILV FT RRGVSSPPVELPPGNPTADTPSPTQRLTQQILWDRLCAALTPGNVVLADQGTAFYGMVE FT HRLPRGVTFIGQPLWGSIGYTLPAALGAGLAHRNRRTVLLLGDGAAQLTIQELGSFYRE FT GLSPVIVVVNNDGYTIERAIHGATAPYNNIARWRWTDIPGALGVANHSSFRAETYGELD FT EAFAVAAELKDQMVFVEVIVPKLDLPSLLTALTRPAQDSNRIFQLPNPGWDN" FT misc_feature 228172..229719 FT /note="Pfam match to entry PF00205 TPP_enzymes, Thiamine FT pyrophosphate enzymes, score 351.90, E-value 8.6e-109" FT misc_feature 228535..228567 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature 228847..228870 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(229871..230885) FT /pseudo FT /transl_table=11 FT /gene="ML2168" FT /product="acyl-CoA synthase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT fadD16 (Best blastx score 254)" FT CDS complement(230448..230885) FT /pseudo FT /transl_table=11 FT /gene="fadD3" FT /gene_synonym="ML2169" FT /product="acyl-CoA synthase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT fadD3 (Best blastx score 124)" FT CDS complement(231359..231583) FT /transl_table=11 FT /gene="ML2170" FT /product="hypothetical protein" FT /note="no database matches." FT /db_xref="UniProtKB/TrEMBL:Q9CBD5" FT /protein_id="CAC31125.1" FT /translation="MMDDCGVRFAHLGCNVGFGQYQVQSAETIDIICCSGEKVVMIEKI FT FLRKDCADHTDMVAIDVESKFLASGSSFE" FT CDS 233431..234828 FT /pseudo FT /transl_table=11 FT /gene="ML2171" FT /product="similar to several L-ascorbate oxidases FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0846c (Best blastx score 209)" FT CDS 235397..235753 FT /transl_table=11 FT /gene="ML2172" FT /product="hypothetical protein" FT /note="no database matches." FT /db_xref="UniProtKB/TrEMBL:Q9CBD4" FT /protein_id="CAC31127.1" FT /translation="MLKNTHIINSTVSFAITVNGTSTAFRIDDAFTCWMYSKGDRLEHN FT LPNSGWDCARSALSDLVYRALSAGMVVDDTGMKFNVHGHTDGAGFLIRIQRHCRPSALG FT GPDQRTTRTALATQ" FT repeat_region 235964..235990 FT /note="9 copies of GTA triplet repeat" FT CDS 236531..236734 FT /pseudo FT /transl_table=11 FT /gene="ML2173" FT /product="possible oxidoredutase (pseudogene)" FT CDS 238291..238695 FT /transl_table=11 FT /gene="cdd" FT /gene_synonym="ML2174" FT /product="cytidine deaminase" FT /note="Similar to Mycobacterium tuberculosis cytidine FT deaminase TR:O53367 (EMBL:AL021841) fasta scores: E(): FT 3e-28, 56.8% in 132 aa, and to Mus musculus cytidine FT deaminase SW:CDD_MOUSE (P56389) fasta scores: E(): 5.2e-12, FT 39.8% in 118 aa. Contains Pfam match to entry PF00383 FT dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase FT zinc-binding region. Contains PS00903 Cytidine and FT deoxycytidylate deaminases zinc-binding region signature." FT /db_xref="GOA:Q9CBD3" FT /db_xref="HSSP:1MQ0" FT /db_xref="InterPro:IPR002125" FT /db_xref="InterPro:IPR006262" FT /db_xref="InterPro:IPR016192" FT /db_xref="InterPro:IPR016193" FT /db_xref="UniProtKB/TrEMBL:Q9CBD3" FT /protein_id="CAC31129.1" FT /translation="MGDVNWDTLQKAAVAARANSYAPYSNFPVGVAGFVNDGRLITGVN FT VENASYGLALCAECSMISALYATGGGRLVAVYCVDGNGDSLMPCGRCRQLLYEHGGPEL FT KIMTPKGVQTMAQLLPQAFNPQERIFGNDE" FT misc_feature 238354..238602 FT /note="Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine FT and deoxycytidylate deaminase zinc-binding region, score FT 62.30, E-value 1e-14" FT misc_feature 238456..238578 FT /note="PS00903 Cytidine and deoxycytidylate deaminases FT zinc-binding region signature" FT CDS 238727..239150 FT /pseudo FT /transl_table=11 FT /gene="ML2175" FT /product="possible sugar transporter (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3728 (Best blastx score 74)" FT CDS 240337..240594 FT /transl_table=11 FT /gene="ML2176" FT /product="hypothetical protein" FT /note="no database matches." FT /db_xref="UniProtKB/TrEMBL:Q9CBD2" FT /protein_id="CAC31131.1" FT /translation="MSGPVYDPSVVKLLAFAVSHGDEQLNQAIEFCHGDEPTVDLLRVI FT AEQRPVKVLSCVLTDAEEIVLNTSIATTPYTSEPVCSTQS" FT CDS complement(240747..241700) FT /transl_table=11 FT /gene="ML2177" FT /product="probable uridine phosphorylase" FT /note="Similar to Mus musculus uridine phosphorylase FT SW:UDP_MOUSE () fasta scores: E(): 1.9e-21, 34.0% in 268 FT aa, and to Homo sapiens uridine phosphorylase SW:UDP_HUMAN FT () fasta scores: E(): 2.2e-19, 32.4% in 275 aa. Contains FT PS01232 Purine and other phosphorylases family 1 FT signature." FT /db_xref="GOA:Q9CBD1" FT /db_xref="InterPro:IPR000845" FT /db_xref="InterPro:IPR010059" FT /db_xref="InterPro:IPR018016" FT /db_xref="InterPro:IPR018017" FT /db_xref="UniProtKB/TrEMBL:Q9CBD1" FT /protein_id="CAC31132.1" FT /translation="MRRFPCVRRIGEVEVKTENINYAFLDGVLDGSHEDVYYHFGIASS FT DPALDELRDVKAVILAGTRERITTFADRWSELNGGSKVSRVIAFSKEDRFVTRYTAGVL FT FASHGMGMASASIALQELMRLVFFLKRGDLEALDKVFWCRVGTSGGIGLPSGTVVVSSE FT GLMADLQPYRLLRGGDSEYWFDGCFPAGTHNAIIAANEGIDDLAMVSGRTVSGNEFFLE FT QFRLDGAVCFETPTTKMAWLRWLDENGVRNIEMEGAMIAGYLNHWGFPKFAMICCTLLN FT RLEGDQVTATPVQLHKFSEDLGAALFNYLKVSLLNA" FT misc_feature complement(241335..241382) FT /note="PS01232 Purine and other phosphorylases family 1 FT signature" FT CDS complement(241941..242192) FT /transl_table=11 FT /gene="ML2178" FT /product="hypothetical protein" FT /note="no database matches." FT /db_xref="UniProtKB/TrEMBL:Q9CBD0" FT /protein_id="CAC31133.1" FT /translation="MSWEKFASDGKRHSGGPPLHCTYCARHLIDALLPKIPKSIDDSDW FT IIDVGERGWVVITNYKRIRISSIEVQMLIEHHLKVVHL" FT CDS complement(242243..242906) FT /pseudo FT /transl_table=11 FT /gene="ML2179" FT /product="putative transcriptional regulator (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2308 (Best blastx score 240)" FT tRNA complement(246728..246804) FT /gene="pheU" FT /note="tRNA Phe anticodon GAA, Cove score 79.14" FT tRNA complement(246833..246909) FT /gene="aspT" FT /note="tRNA Asp anticodon GTC, Cove score 87.88" FT tRNA complement(246940..247012) FT /gene="gluT" FT /note="tRNA Glu anticodon TTC, Cove score 65.04" FT tRNA 247136..247208 FT /gene="lysT" FT /note="tRNA Lys anticodon TTT, Cove score 79.95" FT CDS 247404..247839 FT /pseudo FT /transl_table=11 FT /gene="ML2180" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0831c (Best blastx score 117)" FT CDS complement(247981..248561) FT /pseudo FT /transl_table=11 FT /gene="ML2181" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0830" FT CDS 248931..249273 FT /pseudo FT /transl_table=11 FT /gene="ML2182" FT /product="transcriptional regulator (ArsR family) FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0827c (Best blastx score 201)" FT CDS complement(249422..250446) FT /pseudo FT /transl_table=11 FT /gene="ML2183" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0826 (Best blastx score 263)" FT repeat_region 249885..249918 FT /note="17 copies of AT repeat" FT CDS 250520..251167 FT /pseudo FT /transl_table=11 FT /gene="ML2184" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0825c (Best blastx score 227)" FT CDS 251366..252382 FT /transl_table=11 FT /gene="desA1" FT /gene_synonym="ML2185" FT /product="acyl-[ACP] desaturase" FT /note="Similar to Mycobacterium tuberculosis protein desA1 FT TR:Q50824 (EMBL:U49839) fasta scores: E(): 0, 79.9% in 338 FT aa, and to Oryza sativa acyl-[acyl-carrier protein] FT desaturase precursor SW:STAD_ORYSA (Q40731) fasta scores: FT E(): 2e-19, 28.3% in 300 aa." FT /note="Similar to and ML1952" FT /db_xref="GOA:Q50050" FT /db_xref="InterPro:IPR005067" FT /db_xref="InterPro:IPR009078" FT /db_xref="InterPro:IPR012348" FT /db_xref="UniProtKB/TrEMBL:Q50050" FT /protein_id="CAC31140.1" FT /translation="MSAELTDLQLLHELEPVVEKYMNRHERLHKNWNPHDYIPWSDGKN FT FYALGGQDWDPEQSQLSDVAQVAMVQNLVTEDNLPSYHREIAMTMGMDGAWGQWVNRWT FT AEENRHGIALRDYLVVTRAVDPVELEKLRIEVVNRGFSPGQNHQGGLFADTLFDSILYV FT TFQELATRVSHRNTGKACNETIADQLLAKISSDENLHMIFYRDVSEAGIELAPNLAIKA FT LHKILHNFKMPGFLVPEFRRKAVIIAVGGVYDIRIHLDEVVMPVLKKWRILEREDFSGE FT GTRLRDEIGEHLTELEAACDKFEVSKQRYIEREARRTEKITARKVLSTEGTLRMSGR" FT misc_feature 252426..253463 FT /note="Pfam match to entry PF01207 UPF0034, Uncharacterized FT protein family UPF0034, score 518.10, E-value 6.4e-152" FT CDS 252426..253580 FT /transl_table=11 FT /gene="ML2186" FT /product="transcriptional regulator (NifR3/Smm1 family)" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 41.4 kda protein rv0823c SW:Y823_MYCTU (O53835) fasta FT scores: E(): 0, 82.8% in 396 aa, and to Rhodobacter FT capsulatus nitrogen regulation protein NifR3 SW:NIR3_RHOCA FT (Q08111) fasta scores: E(): 2.6e-28, 34.0% in 332 aa. FT Contains Pfam match to entry PF01207 UPF0034, FT Uncharacterized protein family UPF0034. Contains PS01136 FT uncharacterized protein family UPF0034 signature." FT /db_xref="GOA:Q50049" FT /db_xref="InterPro:IPR001269" FT /db_xref="InterPro:IPR004652" FT /db_xref="InterPro:IPR013785" FT /db_xref="InterPro:IPR018517" FT /db_xref="UniProtKB/Swiss-Prot:Q50049" FT /protein_id="CAC31141.1" FT /translation="MLAPMAGVTNVTFRTLCREFGSTRGNLLRPAPPHLRSPLEQSQVG FT TISGLYVCEMVTARALVERNAVTIHMTTFAPDESPRSLQLYTVDPATTYTAAKMVADEG FT LADHIDMNFGCPMPKVTRRGGGAALPYKRRLFGQIVAAAVRATEGTKIPVTVKFRIGID FT DEHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWAQIAQLKQQVRTIPVLGNGDI FT YDASDALAMMAVTGCDGVVIGRGCLGRPWLFAELSAAFTGRPAPAPPTLGEVAEIVRRH FT GKLLVAHFGEDKGMRDIRKHIAWYLHGFPAGSELRNALALVKTLDELDCLLNRLDGAVP FT FPDAAIGPRGRQGSPAWVALPDSWLTDPDDCTVPIGADIMESGG" FT misc_feature 252750..252806 FT /note="PS01136 Uncharacterized protein family UPF0034 FT signature" FT CDS 254262..255665 FT /pseudo FT /transl_table=11 FT /gene="ML2187" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0822c (Best blastx score 723)" FT CDS 255728..256396 FT /transl_table=11 FT /gene="phoY1" FT /gene_synonym="ML2188" FT /product="phosphate transport system regulator" FT /note="Similar to Mycobacterium tuberculosis phosphate FT transport system regulatory protein TR:O53833 FT (EMBL:AL022004) fasta scores: E(): 0, 93.0% in 213 aa, and FT to Rhizobium meliloti phosphate transport system regulatory FT protein SW:PHOU_RHIME (Q52989) fasta scores: E(): 1.5e-15, FT 30.1% in 216 aa." FT /db_xref="GOA:Q50047" FT /db_xref="InterPro:IPR008170" FT /db_xref="UniProtKB/Swiss-Prot:Q50047" FT /protein_id="CAC31143.1" FT /translation="MRTAYHEQLSELSERLSEMCGLAGIAMERATQALLQADLMLAEQV FT ITDHEKIATRSARAEESAFVLLALQAPVAGDLRAIVSAIQMVAAIDRMGALALHVAKTA FT RRRHPQHVLPEEVNGYFAEIGRVAVELGNGAQEVVLSRDPEKAAQIREKDDAMDELHRH FT LFSVLMDREWKHGVAAAVDVTLLGRFYERFADHAVEVARRVIFQATGSFPEDDTVPGSR FT " FT CDS complement(256423..257199) FT /transl_table=11 FT /gene="phoT" FT /gene_synonym="ML2189" FT /product="phosphate transport system ABC transporter" FT /note="Similar to Mycobacterium tuberculosis phosphate FT transport system ATP-binding protein TR:O53832 FT (EMBL:AL022004) fasta scores: E(): 0, 91.5% in 258 aa, and FT to Escherichia coli phosphate transport ATP-binding protein FT pstb SW:PSTB_ECOLI (P07655) fasta scores: E(): 0, 52.9% in FT 255 aa. Contains Pfam match to entry PF00005 ABC_tran, ABC FT transporter. Contains PS00017 ATP/GTP-binding site motif A FT (P-loop). Contains PS00211 ABC transporters family FT signature." FT /note="Similar to ML1892, ML1114, ML1113, ML1122, ML1089, FT ML1424, ML0336, ML2352, ML1726, ML0669, ML0590 and ML1816" FT /db_xref="GOA:Q50046" FT /db_xref="InterPro:IPR003439" FT /db_xref="InterPro:IPR003593" FT /db_xref="InterPro:IPR005670" FT /db_xref="InterPro:IPR015850" FT /db_xref="InterPro:IPR017871" FT /db_xref="UniProtKB/Swiss-Prot:Q50046" FT /protein_id="CAC31144.1" FT /translation="MAKRLDLKGVNIYYGSFQAVLDVSLAVLPRSVTAFIGASGCGKTT FT VLRTLNRMHEVVPGARVEGTVLLDDEDIYAPGIDPVGVRRAIGMVFQRPNPFPAMSIRD FT NVVAGLKLQGVRNRKVLDDTAEYFLRGTNLWDEVKDRLDKPGGGLSGGQQQRLCIARAI FT AVQPDVLLMDEPCSSLDPISTMAIEELIGELKQEYTIVIVTHNMQQAARVSDQTAFFNL FT EAVGRPGRLVEIDDTEKIFSNPTEKATEDYISGRFG" FT misc_feature complement(256531..257112) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 197.30, E-value 2.4e-55" FT misc_feature complement(256711..256755) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(257068..257091) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(257279..257899) FT /pseudo FT /transl_table=11 FT /gene="pstA3" FT /gene_synonym="ML2190" FT /product="PstA component of phosphate uptake (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT pstA2 (Best blastx score 279). Note M. tuberculosis does FT not have pstA3 gene" FT CDS complement(258092..258848) FT /pseudo FT /transl_table=11 FT /gene="pstC3" FT /gene_synonym="ML2191" FT /product="membrane-bound component of phosphate transport FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT pstC3 (Best blastx score 327). Note M. tuberculosis does FT not have pstC3 at this location" FT CDS complement(258981..260270) FT /transl_table=11 FT /gene="phoS3" FT /gene_synonym="ML2192" FT /product="phosphate-binding protein 3 precursor" FT /note="Similar to Mycobacterium tuberculosis FT phosphate-binding protein 3 precursor TR:O86343 FT (EMBL:Z95209) fasta scores: E(): 0, 46.5% in 372 aa, and to FT Mycobacterium tuberculosis protein antigen B precursor FT SW:PAB_MYCTU (P15712; O05868) fasta scores: E(): 1.4e-24, FT 33.1% in 369 aa, and to Escherichia coli phosphate-binding FT periplasmic protein precursor SW:PSTS_ECOLI (P06128; FT P76744) fasta scores: E(): 1.3e-20, 27.9% in 344 aa. FT Contains Pfam match to entry PF01449 PstS, FT Phosphate-binding protein. Contains PS00013 Prokaryotic FT membrane lipoprotein lipid attachment site. Note M. FT tuberculosis does not have phoS3 at this location" FT /note="Similar to ML2095" FT /db_xref="GOA:Q50043" FT /db_xref="InterPro:IPR005673" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:Q50043" FT /protein_id="CAC31147.1" FT /translation="MTERKPSFMQYSPVLFTPIAMFLGSCGAYFPGDQATLRSASGAGV FT RRKCAEKARSVNHDKVCRAFAMVLTTAVTAGVLSACGSDVNRGHTATTSISGKSADTAA FT CGGKRTMTAEGSTAQQNAIALFNQIWGKLCPDKTVSYNPTGSGAGREQFIAGRIDFAGS FT DSPLLADQLGPAAKRCKGNPAWDLPLVFGPVALVYNLPGVQMLTVNSDVLAKIFSGVIT FT TWNDGILAALNPGVVLPNLRIMPIYRADASGTTDNLQKYLTTDAPQSWAKGVGAEFQGG FT VGEGVQKSAGVIQAVQTTPGAFGYVEKSFADRAGLPFAQIDTGSGGVPLTDDTARNGIN FT AANFVSVGNDLVLDLNAMYSTEQSNAYPLVLATYEIVCSKGYDPDTFAAIKSFLTVAAN FT DGQAGLAAVGYVPLPDTIKKRLVSAINAMQ" FT misc_feature complement(259089..259952) FT /note="Pfam match to entry PF01449 PstS, Phosphate-binding FT protein, score 393.80, E-value 1.7e-114" FT misc_feature complement(260193..260225) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(260263..261198) FT /transl_table=11 FT /gene="ML2193" FT /product="putative acetyltransferase" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 33.6 kda protein TR:O53831 (EMBL:AL022004) fasta scores: FT E(): 0, 75.2% in 314 aa. Contains Pfam match to entry FT PF00583 Acetyltransf, Acetyltransferase (GNAT) family." FT /db_xref="GOA:Q9CBC9" FT /db_xref="HSSP:1P0H" FT /db_xref="InterPro:IPR000182" FT /db_xref="InterPro:IPR016181" FT /db_xref="InterPro:IPR017813" FT /db_xref="UniProtKB/TrEMBL:Q9CBC9" FT /protein_id="CAC31148.1" FT /translation="MVLNWRFALSADEQRLVREIISAATEFDEVSPVGEQVLRELGYDR FT TEHLLVTDSRPYAPIIGYLNLSSPRDAGVAMAELVVHPRERRRGVGAAMVRAALAKTGG FT RNRFWAHGTLASARATASVLGLVPVRELVQMQRSLRTIPDPMVPDQLGVWVRTYVGTVD FT DAELLRVNNAAFAGHPEQGGWTATQLAERRSEPWFDPAGLFLAFGDSSSNQPGKLLGFH FT WTKVHAAHPGLGEVYVLGVDPSAQGRGLGQMLTSIGIASLAQRLVGPSAEPTVMLYVES FT DNVAAARTYERLGFTTYSVDTAYALARIDD" FT misc_feature complement(260311..260724) FT /note="Pfam match to entry PF00583 Acetyltransf, FT Acetyltransferase (GNAT) family, score 10.60, E-value 0.09" FT CDS complement(261201..261968) FT /pseudo FT /transl_table=11 FT /gene="ML2194" FT /product="two-component response regulator (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0818 (Best blastx score 209)" FT CDS 262115..262966 FT /transl_table=11 FT /gene="ML2195" FT /product="probable exported protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 28.6 kda protein TR:O53829 (EMBL:AL022004) fasta scores: FT E(): 0, 73.0% in 270 aa. Contains a possible N-terminal FT signal sequence." FT /db_xref="UniProtKB/TrEMBL:Q50040" FT /protein_id="CAC31150.1" FT /translation="MVKDATCIKVRHNMRMRKVLTSVIATVVTMAVLVVGVLGIDYGTS FT IYAEYLLSVNVRNAANLGSDPFVAILAFPFIPQAMRDHYTELEIKANAVDHAMVGKASL FT EATMYSIDLTYASWLIKPDAKLPVDRLESRIIIDSMHLGQYLGISDLMVEAPHRETNNA FT TGGTTESGISSGHGLVLSGTPKSANFDHRVSVLVDLSIAPEDQATLVFTPTGIATGPDT FT ANQPVPDDKRNPVLRAFSARMSDQRLPFGVAPTSEGARGSDVIIEGITQGVTITLDGFK FT QS" FT CDS 263059..263481 FT /transl_table=11 FT /gene="thiX" FT /gene_synonym="ML2196" FT /product="thiredoxin" FT /note="Similar to Mycobacterium tuberculosis putative FT thioredoxin TR:O53828 (EMBL:AL022004) fasta scores: E(): FT 1.1e-30, 63.8% in 141 aa, and to Anacystis nidulans FT thioredoxin 1 SW:THI1_ANANI (P12243) fasta scores: E(): FT 9e-07, 37.6% in 93 aa. Contains PS00194 Thioredoxin family FT active site." FT /note="Similar to and ML2703" FT /db_xref="GOA:Q9CBC8" FT /db_xref="InterPro:IPR012335" FT /db_xref="InterPro:IPR012336" FT /db_xref="InterPro:IPR013766" FT /db_xref="InterPro:IPR015467" FT /db_xref="InterPro:IPR017936" FT /db_xref="InterPro:IPR017937" FT /db_xref="UniProtKB/TrEMBL:Q9CBC8" FT /protein_id="CAC31151.1" FT /translation="MMTAIVATITVGMLTAFTGRWLTRHSGNVHEICSGPGQGTGTDTA FT DLGLSRTGPTIVHFSAPWCGPCDRVRRVVYQVCKDLPDVAHIEIDLDTNPAAVRRFSVL FT SLPTTLIFDTDGQQRYRTSGVPKAFDLLSTLEPLLA" FT misc_feature 263224..263280 FT /note="PS00194 Thioredoxin family active site" FT CDS 263694..264179 FT /transl_table=11 FT /gene="ML2197" FT /product="integral membrane protein" FT /note="Similar to Saccharopolyspora erythraea hypothetical FT 16.0 kda protein TR:Q54082 (EMBL:M29612) fasta scores: E(): FT 4.9e-15, 43.9% in 139 aa. Contains possible membrane FT spanning hydrophobic domains." FT /db_xref="UniProtKB/TrEMBL:Q50037" FT /protein_id="CAC31152.1" FT /translation="MTINNTTTGVEVVDVRGPRFAAWVTAAVLQTVLIISVVSPLAAAL FT LLVLQAVVFATGTLGGPRRHPYGRVFAALVAPRLGPVKEREPVPPLKFAQLLGFVFVVC FT GVTGFAAGAFLVGVIATAAALVAAFLNAAFGICLGCQLYPVVVWFRRTAAPRNRNPG" FT CDS 264211..265044 FT /transl_table=11 FT /gene="cysA3" FT /gene_synonym="ML2198" FT /product="thiosulfate sulfurtransferase" FT /note="Similar to Mycobacterium tuberculosis putative FT thiosulfate sulfurtransferase SW:THTR_MYCTU (O05793) fasta FT scores: E(): 0, 85.2% in 277 aa, and to Saccharopolyspora FT erythraea putative thiosulfate sulfurtransferase FT SW:THTR_SACER (P16385) fasta scores: E(): 0, 74.1% in 274 FT aa, and to Corynebacterium glutamicum thiosulfate FT sulfurtransferase SW:THTR_CORGL (P71121) fasta scores: E(): FT 0, 44.5% in 218 aa. Contains 2 Pfam matches to entry FT PF00581 Rhodanese, Rhodanese-like domain. Contains PS00683 FT Rhodanese C-terminal signature." FT /note="Similar to and ML0728" FT /db_xref="GOA:Q50036" FT /db_xref="InterPro:IPR001307" FT /db_xref="InterPro:IPR001763" FT /db_xref="UniProtKB/Swiss-Prot:Q50036" FT /protein_id="CAC31153.1" FT /translation="MARSDVLVSADWAESNLDSANIVFVEVDEDTSTYDGDHIAGAIKL FT DWRADLQDPIKRDFIDTQQFSKLLGDRGISNDNTVILYGGNNNWFAAYAYWYFKLYRHD FT KVKLLDGGRKKWELDGRPLSTDTVTRPATSYAAAAPDNTIRAFRDEVIASIKIKNLVDV FT RSPDEFSGKLLAPAHLPQEQSQRPGHIPSAINIPWSKAANEDGTFKSDEQLAKLYADAG FT LDRLKETIVYCRIGERSSHTWFVLRELLGYQNVKNYDGSWTEYGSLVGVPIELGS" FT misc_feature 264235..264567 FT /note="Pfam match to entry PF00581 Rhodanese, FT Rhodanese-like domain, score 77.30, E-value 3.2e-19" FT misc_feature 264649..265014 FT /note="Pfam match to entry PF00581 Rhodanese, FT Rhodanese-like domain, score 98.70, E-value 1.1e-25" FT misc_feature 264973..265005 FT /note="PS00683 Rhodanese C-terminal signature" FT CDS 265046..265348 FT /transl_table=11 FT /gene="ML2199" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 10.2 kda protein TR:O05794 (EMBL:Z95150) fasta scores: E(): FT 6.5e-33, 84.0% in 100 aa, and to Saccharopolyspora FT erythraea hypothetical 10.2 kda protein TR:Q54084 FT (EMBL:M29612) fasta scores: E(): 2.7e-16, 53.0% in 100 aa." FT /db_xref="InterPro:IPR008969" FT /db_xref="InterPro:IPR010814" FT /db_xref="UniProtKB/TrEMBL:Q9CBC7" FT /protein_id="CAC31154.1" FT /translation="MCSEPKQRLALPANVNLEKETVITGRVVDRKGQAVGGAFVRLLDS FT SNEFTAEVVTSATGDFRFFAAPGSWTLRALSSVGNGDAMMSPSGTGIHKVDVKIT" FT CDS 265607..266293 FT /transl_table=11 FT /gene="ML2200" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 23.9 kda protein TR:O53827 (EMBL:AL022004) fasta scores: FT E(): 0, 78.9% in 223 aa, and to Streptomyces coelicolor FT hypothetical 21.7 kda protein TR:CAB94083 (EMBL:AL358692) FT fasta scores: E(): 4.4e-11, 30.5% in 167 aa." FT /db_xref="GOA:Q9CBC6" FT /db_xref="InterPro:IPR014878" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBC6" FT /protein_id="CAC31155.1" FT /translation="MTSDEVRDGAGSPADSSKGNKCTAAGMFQAAKRSTVSAARNIPAF FT DDLPVPSDTANLREGANLNSTLLALLPLVGVWRGEGEGRGPNGDYHFGQQIVVSHDGGN FT YLNWEARSWRLNDAGEYQETSLRETGFWRFVSDPYDPTESQAIELLLAHSAGYVELFYG FT RPRNASSWELVTDALACSKSGVLVGGAKRLYGIVEGGDLAYVEERVDADGGLVPNLSAR FT LYRFAG" FT CDS complement(267598..267837) FT /transl_table=11 FT /gene="ML2201" FT /product="hypothetical protein" FT /note="no database matches." FT /db_xref="UniProtKB/TrEMBL:Q9CBC5" FT /protein_id="CAC31156.1" FT /translation="MVDLGSGAIGHVVSKPQYAQELADIASNAGVIAVLDKSDREFDQQ FT LNLLLRVESFFRQSVTQPRFCSKRHRRLVGQLVR" FT CDS complement(268918..269788) FT /pseudo FT /transl_table=11 FT /gene="pabC" FT /gene_synonym="ML2202" FT /product="aminodeoxychorismate lyase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT pabC (Best blastx score 299)" FT CDS 269999..271120 FT /transl_table=11 FT /gene="ML2203" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 39.4 kda protein RV0811C TR:O53825 (EMBL:AL022004) fasta FT scores: E(): 0, 77.4% id in 367 aa, and to Corynebacterium FT ammoniagenes orf4 TR:Q9RHX9 (EMBL:AB003158) fasta scores: FT E(): 1.5e-13, 40.5% id in 373 aa." FT /db_xref="GOA:Q9CBC4" FT /db_xref="InterPro:IPR006222" FT /db_xref="InterPro:IPR017703" FT /db_xref="UniProtKB/TrEMBL:Q9CBC4" FT /protein_id="CAC31158.1" FT /translation="MRGRATHVNAVLAPDPGPDAGAIWHFGDPLGEQRSAETDAVLVDR FT SHRATLTLIGSDRQTWLHSISTQHVSALPDGASTQNLSLDSQGRVEDHWIQTELGGTTY FT LDTEPWRGEPLLEYLRKMVFWSEVTPGSADMAMLSLLGPRLTEQAVHNALYLDALPDES FT TAVPLTAGSFVRRIPGAPAGQIELDLLVPRRESADWQSRLAGVGVRSAGMWAYEAHRVA FT ALRPRLGVDTDQRTIPHEVGWIGGPGEGAVHLDKGCYRGQETVARVQNLGKPPRMLVLL FT HLDGSVERTSTGDAVLANSGAVGRLGTVVEHVDLGPVALALLKRGLPTDTELTIELEGP FT QDGSVAAVIDPDSLPAADEIGVGRLAIERLRGR" FT CDS 271289..271477 FT /transl_table=11 FT /gene="ML2204" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 6.9 kda protein RV0810C TR:O53824 (EMBL:AL022004) fasta FT scores: E(): 9.9e-17, 77.8% id in 63 aa, and to FT Streptomyces coelicolor hypothetical 9.3 kda protein FT SCD25.24C TR:Q9RKJ8 (EMBL:AL118514) fasta scores: E(): FT 1.3e-06, 46.8% id in 62 aa." FT /db_xref="UniProtKB/TrEMBL:Q9CBC3" FT /protein_id="CAC31159.1" FT /translation="MGRGRAKAKQTKVARELKYSSPQTDFQRLQRELSSTGAADPGQLD FT GDDRVSEDSWDEDAWRR" FT CDS complement(271571..272665) FT /transl_table=11 FT /gene="purM" FT /gene_synonym="ML2205" FT /product="5'-phosphoribosyl-5-aminoimidazole synthase" FT /note="Similar to Mycobacterium tuberculosis FT 5'-phosphoribosyl-5-aminoimidazole synthetase RV0809 FT TR:O53823 (EMBL:AL022004) fasta scores: E(): 0, 87.1% id in FT 364 aa, and to Bacillus subtilis FT phosphoribosylformylglycinamidine cyclo-ligase PURM FT SW:PUR5_BACSU (P12043) fasta scores: E(): 0, 46.4% id in FT 334 aa. Contains Pfam match to entry PF00586 AIRS, AIR FT synthase related protein." FT /db_xref="GOA:Q9CBC2" FT /db_xref="HSSP:1CLI" FT /db_xref="InterPro:IPR000728" FT /db_xref="InterPro:IPR004733" FT /db_xref="InterPro:IPR010918" FT /db_xref="InterPro:IPR016188" FT /db_xref="UniProtKB/TrEMBL:Q9CBC2" FT /protein_id="CAC31160.1" FT /translation="MMDPGKSPGGQLGNHGITYASTGVDIEAGDRSVELFKPMAVKAIR FT TEVLGGLGGFAGLFALRSGYREPVLAASTDGVGTKLAVAQAMDKHDTVGLDLVAMVVDD FT LVVCGAEPLFLQDYIAVGRTVPERLSAIVDGIAEGCMLAGCALLGGETAEHPGLMEVDH FT YDIAATGVGVVEADDTLGPDRVKPGDVIIALRSSGLHSNGYSLARSVLLEIDRMNLAGY FT VEEFGRTLGEELLEPTRIYAKDCLALAAETHVRTFCHVTGGGLAGNLQRVIPHGLVAEV FT DRGTWTPAPVFAMIAQRGRVAREEMEKTFNMGVGMIAVVAPEDTDRALAILTARHLDCW FT VLGTVCKGSKVGPRAKLVGQHPRF" FT misc_feature complement(271625..272572) FT /note="Pfam match to entry PF00586 AIRS, AIR synthase FT related protein, score 391.30, E-value 9.3e-114" FT CDS complement(272765..274435) FT /transl_table=11 FT /gene="purF" FT /gene_synonym="ML2206" FT /product="amidophosphoribosyltransferase" FT /note="Similar to Mycobacterium tuberculosis FT amidophosphoribosyltransferase precursor RV0808 FT SW:PUR1_MYCTU (O06626) fasta scores: E(): 0, 91.3% id in FT 518 aa, and to Bacillus subtilis FT amidophosphoribosyltransferase precursor PURF SW:PUR1_BACSU FT (P00497) fasta scores: E(): 0, 45.1% id in 470 aa. Contains FT 2 Pfam matches to entry PF00310 GATase_2, Glutamine FT amidotransferases class-II. Contains Pfam match to entry FT PF00156 Pribosyltran, Phosphoribosyl transferase domain. FT Contains PS00103 Purine/pyrimidine phosphoribosyl FT transferases signature." FT /db_xref="GOA:Q50028" FT /db_xref="InterPro:IPR000583" FT /db_xref="InterPro:IPR000836" FT /db_xref="InterPro:IPR005854" FT /db_xref="InterPro:IPR017932" FT /db_xref="UniProtKB/Swiss-Prot:Q50028" FT /protein_id="CAC31161.1" FT /translation="MCLAVGVGVRAPKHVPQIRRLGRAGRRLRCVTNCALGSCPIVTVQ FT QPGRDFSSPREECGVFGVWAPGELVAKLTYFGLYALQHRGQEAAGIAVADGSQVLVFKD FT LGLVSQVFDEQTLAAMEGHVAIGHCRYSTTGDTTWENAQPVFRNIAAGSGVALGHNGNL FT VNTAELAARARDAGLIAKRCPAPATTDSDILGALLAHGAADSTLEQAALELLPTVRGAF FT CLTFMDENTLYACRDPYGVRPLSLGRLDRGWVVASETAGLDIVGASFVRDIEPGELLAI FT DADGVRSTRFANPTPKGCVFEYVYLARPDSTLAGRSVHGTRVEIGRRLARECPVEADLV FT IGVPESGTPAAVGYAQESGISYGQGLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVI FT RGKRLIVVDDSVVRGNTQRALVRMLREAGAVELHVRIASPPVKWPCFYGIDFPSPAELI FT ANVVADEEEMLEAVRQGIGADTLGYISLRGMIAASEQPASRLCYACFDGRYPIELPSEA FT MLGKNVIEHMLANAARGAGLRDLAADQVPVDADENCVWR" FT misc_feature complement(273044..273511) FT /note="Pfam match to entry PF00156 Pribosyltran, FT Phosphoribosyl transferase domain, score 22.90, E-value FT 0.00029" FT misc_feature complement(273188..273226) FT /note="PS00103 Purine/pyrimidine phosphoribosyl FT transferases signature" FT misc_feature complement(273695..273871) FT /note="Pfam match to entry PF00310 GATase_2, Glutamine FT amidotransferases class-II, score 34.80, E-value 3.1e-11" FT misc_feature complement(273929..274264) FT /note="Pfam match to entry PF00310 GATase_2, Glutamine FT amidotransferases class-II, score 99.70, E-value 2.2e-33" FT CDS complement(274447..274842) FT /transl_table=11 FT /gene="ML2207" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT protein Rv0807 or MTCY07H7A.02C TR:O06627 (EMBL:Z95618) FT (129 aa) fasta scores: E(): 0, 73.4% id in 128 aa. Similar FT to Corynebacterium ammoniagenes ORF3 TR:Q9RHY2 FT (EMBL:AB003158) (132 aa) fasta scores: E(): 4.4e-22, 51.2% FT id in 125 aa and to Streptomyces coelicolor hypothetical FT protein SCD25.20 TR:Q9RKK0 (EMBL:AL118514) (202 aa) fasta FT scores: E(): 6.6e-16, 52.5% id in 101 aa. Previously FT sequenced as TR:O05761 (EMBL:Z95151)." FT /db_xref="UniProtKB/TrEMBL:O05761" FT /protein_id="CAC31162.1" FT /translation="MAVCDRADPAKTRQAVLALADWLKDRTLPAPDRDAVATAVRLTVR FT TLATLAPGASVEVRIPPYVAVQCVSGPSHTRGTPPNVVETDSRTWLLVATGLMQLVEAV FT ATGALRMSGSRAGDIEVWMPLINLRCT" FT CDS 274895..276009 FT /pseudo FT /transl_table=11 FT /gene="mce1" FT /gene_synonym="ML2208" FT /product="cell invasion protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT mce1 (Best blastx score 226)" FT CDS 276474..278102 FT /transl_table=11 FT /gene="cpsY" FT /gene_synonym="ML2209" FT /product="probable UDP-glucose-4-epimerase" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 60.3 kda protein RV0806C TR:O06628 (EMBL:Z95618) fasta FT scores: E(): 0, 82.3% id in 530 aa, and to Neisseria FT meningitidis capsule gene complex upd-glucose-4-epimerase FT TR:Q51151 (EMBL:L09188) fasta scores: E(): 9.2e-26, 30.0% FT id in 317 aa." FT /db_xref="GOA:Q50025" FT /db_xref="UniProtKB/Swiss-Prot:Q50025" FT /protein_id="CAC31164.1" FT /translation="MSKIVSCEDDRPVRRTLEPIIVTRQGKVARLESSLTPHEAQIEDL FT IFLRKALNRADIPFLFIRNHKNRPVLAINIKLRPAVERALVTACASEPMYAKTIDERGL FT SPVLVAKGQLSQSIDPRIVRLYRRRIAPGGFRFGSRFGVELQFWSFEETLIRCPVENSL FT TRKVLPRKEVTPATIKLYGYKWHTIEGMFTPHASDVTFDIDLVFSWVDGSDPEFRARRA FT AEMSHHVVGEGDDADARIRQIDELKYALRSVNMFAPWIRRIFIATDSIPPSWLADHPMI FT TIVPAEDHFSDRSALPTYNSHAVESQLHRIPDLSEHFLYSNDDMFFGRPLKASMFFSPG FT GVTRFIEAKTRIGLGTNDPTRSGFENAARVNRQLLLRRFGQLITRHLEHTTVPLRKSVL FT FEMEQEFPEEFARTQESVFRSGTDISVTNSLYHYYALITGRAVQQEKAKVLYVDTTSYT FT GLNLLPELRKRRNYDFFCLNDGSFPEVPATERAERVVSFLERYFPIPAPWEKVATDFNR FT QDFASPTVSAPLEDGQTANPAQTAR" FT CDS complement(278017..278970) FT /transl_table=11 FT /gene="ML2210" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 34.2 kDa protein RV0805 TR:O06629 (EMBL:Z95618) fasta FT scores: E(): 0, 82.5% id in 315 aa, and to Escherichia coli FT IcC protein ICC SW:ICC_ECOLI (P36650) fasta scores: E(): FT 1.2e-12, 30.7% id in 215 aa." FT /db_xref="GOA:Q50024" FT /db_xref="InterPro:IPR004843" FT /db_xref="UniProtKB/TrEMBL:Q50024" FT /protein_id="CAC31165.1" FT /translation="MHRLRAAEHPRPDYVLLHISDTHLISDGSLYGAVDADSRLGELLE FT QLKHSQLRPDAIIFTGDLADRGEPEAYRKLRCLVESFATELDAELFWVMGNHDNRVALR FT TLLLDEAPSMAPLDGVRRVDGLRVITLDTSVPGRHYGEISASQLDWLADELTTSAPDGT FT ILALHHPPIPSVLDMAVTVELRDQASLGRVLKGSDIRAILAGHLHYSTNATFVGIPVSV FT ASATCYTQDLTVVAGGARGRDGAQGCNLVHVYQDTVVHSVIPLGIGNMVGTFVSPAQAR FT RDIAESGLFIEPSGRDSLFAHPPMVLTPSVTQSLGD" FT CDS complement(279103..281367) FT /transl_table=11 FT /gene="purL" FT /gene_synonym="ML2211" FT /product="phosphoribosylformylglycinamidine synthase II" FT /note="Similar to Mycobacterium tuberculosis FT phosphoribosylformylglycinamidine synthase ii PURL OR FT RV0803 OR MTCY07H7A.06C SW:PURL_MYCTU (P54876; O06631) FT fasta scores: E(): 0, 90.3% id in 754 aa, and to Bacillus FT subtilis phosphoribosylformylglycinamidine synthase ii PURL FT SW:PURL_BACSU (P12042) fasta scores: E(): 0, 43.0% id in FT 739 aa. Contains 2 Pfam matches to entry PF00586 AIRS, AIR FT synthase related protein." FT /db_xref="GOA:Q50023" FT /db_xref="InterPro:IPR000728" FT /db_xref="InterPro:IPR010074" FT /db_xref="InterPro:IPR010918" FT /db_xref="InterPro:IPR016188" FT /db_xref="UniProtKB/Swiss-Prot:Q50023" FT /protein_id="CAC31166.1" FT /translation="MIDTVEYAATTPDQPQPFAELGLREDEYQRVREILGRRPTDTELA FT MYSVMWSEHCSYKSSKVHLRYFGETTTEEMRTGMLAGIGENAGVVDIGDGWAVTFKVES FT HNHPSYVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADALDTRRVLDGVVRGI FT GGYGNSLGLPNIGGETVFDSCYDGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGAC FT TGLDGIGGVSVLASDTFDAEGARKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDL FT GGAGLSCATSELASAGDVGMAIQLDTVPRRAKDMTPAEVFCSESQERMCAVVAPENVDA FT FLAVCRKWEVLATVIGEVTDGDRLRITWHGETVVDVPPRTVAHEGPVYQRPVSRPESQE FT ALNADSSKGLPRPVSGDELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEHADAG FT VLRIDESTGRGIALSTDASGRYTRLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFG FT SPEDPGVMWQFAQAVRGLADGCAALKIPVTGGNVSFYNQTGAVAILPTPVVGVLGVLDN FT VARRIHTSLGTEPGEILMLLGDTYDEFDGSVWAQVMAGHLGGLPPMVDLAREKLLAEVL FT SSASRDELVSAAHDLSEGGLAQAIVESALAGETGCRIALPEDADPFVMLFSESAGRVLV FT AVPRPEESRFRSMCEARGLPAMRIGVVDQGSDSIEVRGQFTVSLAELRMTFEAVLPRFF FT G" FT misc_feature complement(279199..280071) FT /note="Pfam match to entry PF00586 AIRS, AIR synthase FT related protein, score 256.50, E-value 3.7e-73" FT misc_feature complement(280288..281181) FT /note="Pfam match to entry PF00586 AIRS, AIR synthase FT related protein, score 319.90, E-value 3.1e-92" FT CDS 281495..282077 FT /pseudo FT /transl_table=11 FT /gene="ML2212" FT /product="acetyltransferase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0802c (Best blastx score 180)" FT CDS complement(282219..283550) FT /transl_table=11 FT /gene="pepC" FT /gene_synonym="ML2213" FT /product="aminopeptidase I" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 46.0 kda protein RV0800 OR MTCY07H7A.09C TR:O06634 FT (EMBL:Z95618) fasta scores: E(): 0, 78.3% id in 433 aa, and FT to Saccharomyces cerevisiae vacuolar aminopeptidase I FT precursor ApE1 SW:AMPL_YEAST (P14904; P22060) fasta FT scores: E(): 5.7e-22, 31.5% id in 454 aa. Contains Pfam FT match to entry PF02127 Peptidase_M18, Aminopeptidase I zinc FT metalloprotease (M18)." FT /db_xref="GOA:Q50022" FT /db_xref="InterPro:IPR001948" FT /db_xref="UniProtKB/Swiss-Prot:Q50022" FT /protein_id="CAC31168.1" FT /translation="MPTLASTTSSPTAMMLGMPASAADLCEFINASPSPFHVCATVAGR FT LLDAGYAELSEVERWPDHPGRYFIVRAGSLVAWSAGQGVKAHAPFRIVGAHTDSPNLRV FT KQHPDLLVAGWRVVALQPYGGAWLNSWLDRDLGVSGRLSVRSAGKGSEITDRLVRIDDP FT ILRVPQLAIHLAEDRKSLTLDPQRHVNAVWGVGDKAGSLLEYVAERTGVAVADVLAVDL FT MTHDLVPSMVIGADANLLSAPRLDNQVSCYAGMEALLASVPHDCLPVLALFDHEEVGST FT SDRGARSNLLSTVLERIVLAAGGGRDDYLRRLPASLLVSADMAHATHPNYPECHEPSHL FT IEVNAGPVLKVHPNLRYATDGRTAAAFEVACQQAGVRLQRYEHRADRPCGSTIGPLASA FT RTGIPTVDVGAAQLAMHSARELMGAHDVAVYSAALQAFFSADLF" FT misc_feature complement(282237..283469) FT /note="Pfam match to entry PF02127 Peptidase_M18, FT Aminopeptidase I zinc metalloprotease (M18), score 831.10, FT E-value 3.9e-246" FT CDS 283570..284215 FT /pseudo FT /transl_table=11 FT /gene="ML2214" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0799c (Best blastx score 233)" FT CDS 284840..285905 FT /pseudo FT /transl_table=11 FT /gene="ML2215" FT /product="probable penicillin binding protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv3627c (Best blastx score 258)" FT CDS complement(286681..286924) FT /pseudo FT /transl_table=11 FT /gene="lpdB" FT /gene_synonym="ML2216" FT /product="dihydrolipoamide dehydrogenase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT lpdB (Best blastx score 153)" FT CDS 286904..287436 FT /pseudo FT /transl_table=11 FT /gene="ML2217" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0790c (Best blastx score 295)" FT CDS 287504..288078 FT /pseudo FT /transl_table=11 FT /gene="ML2218" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0789c (Best blastx score 122)" FT CDS complement(288155..288829) FT /transl_table=11 FT /gene="purQ" FT /gene_synonym="ML2219" FT /product="phosphoribosylformylglycinamidine synthase I" FT /note="Similar to Mycobacterium tuberculosis putative FT phosphoribosylformylglycinamidine synthase I RV0788 OR FT MTCY369.32 TR:P71841 (EMBL:Z80226) fasta scores: E(): 0, FT 88.7% id in 222 aa, and to Bacillus subtilis FT phosphoribosylformylglycinamidine synthase I PURQ FT SW:PURQ_BACSU (P12041) fasta scores: E(): 0, 47.2% id in FT 214 aa. Contains PS00442 Glutamine amidotransferases FT class-I active site." FT /db_xref="GOA:O05756" FT /db_xref="InterPro:IPR010075" FT /db_xref="InterPro:IPR011698" FT /db_xref="InterPro:IPR017926" FT /db_xref="UniProtKB/Swiss-Prot:O05756" FT /protein_id="CAC31174.1" FT /translation="MNARIGVITFPGTLDDVDAARAARHVGAEAVSLWHADADLKGVDA FT VVVPGGFSYGDYLRAGAIARLSPIMTEVVDAVQRGMPVLGICNGFQVLCEAGLLPGALI FT RNVGLHFICRDVWLRVISTSTAWTSRFEPETDLLVSLKSGEGRYVASENVLDELDGEGR FT VVFRYHDNINGSLRDIAGISSANGRVVGMMPHPEHAIEVLTGPSDDGLGLFYSALDSVL FT AS" FT misc_feature complement(288551..288586) FT /note="PS00442 Glutamine amidotransferases class-I active FT site" FT CDS complement(288826..289065) FT /transl_table=11 FT /gene="ML2219A" FT /product="conserved hypothetical protein" FT /note="Unknown but orthologue of M. tuberculosis Rv0787A FT and same as M.leprae MLCB5.24. sp|O05755|Y524_MYCLE FT HYPOTHETICAL 8.6 KDA PROTEIN MLCB5.24 (79 aa) E(): 4.7e-2 FT 8; 98.734% identity in 79 aa overlap. Similar to various FT hypothetical proteins e.g. Streptomyces coelicolor FT hypothetical protein SCD25.13 (AL118514)" FT /db_xref="GOA:O05755" FT /db_xref="InterPro:IPR003850" FT /db_xref="UniProtKB/Swiss-Prot:O05755" FT /protein_id="CAC31175.1" FT /translation="MARAVVHVMLRAEILDPQGQAIAGALGRLGHTGISDVRQGKRFEL FT EIDDTVDDSELAMIAESLLANTVIEDWTITRESQ" FT CDS complement(289202..289439) FT /pseudo FT /transl_table=11 FT /gene="ML2220" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0787 (Best blastx score 111)" FT CDS 289477..289866 FT /pseudo FT /transl_table=11 FT /gene="ML2221" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0786c (Best blastx score 194)" FT CDS complement(289935..291450) FT /pseudo FT /transl_table=11 FT /gene="ML2222" FT /product="putative dehydrogenases (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0785 (Best blastx score 559)" FT CDS complement(291533..292080) FT /pseudo FT /transl_table=11 FT /gene="ML2223" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0784 (Best blastx score 251)" FT CDS 292380..293922 FT /pseudo FT /transl_table=11 FT /gene="ML2224" FT /product="multidrug resistance protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0783c (Best blastx score 460)" FT CDS complement(294060..294311) FT /pseudo FT /transl_table=11 FT /gene="ML2225" FT /product="transcriptional regulator, tetr family FT (pseudogene)" FT /note="Similar to Deinococcus radiodurans transcriptional FT regulator, tetr family DR0720 TR:Q9RWE9 (EMBL:AE001928) FT fasta scores: E(): 1.8, 28.9% id in 83 aa" FT CDS complement(295010..297184) FT /transl_table=11 FT /gene="ptrB" FT /gene_synonym="ML2226" FT /product="protease II" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 60.9 kda protein cy369.26 RV0782 OR MTCY369.26 TR:P71835 FT (EMBL:Z80226) fasta scores: E(): 0, 77.8% id in 519 aa, and FT to Escherichia coli protease ii PTRB OR TLP SW:PTRB_ECOLI FT (P24555; P78068) fasta scores: E(): 0, 38.2% id in 702 aa. FT Contains Pfam match to entry PF00326 Peptidase_S9, Prolyl FT oligopeptidase family." FT /db_xref="GOA:O05748" FT /db_xref="InterPro:IPR001375" FT /db_xref="InterPro:IPR002470" FT /db_xref="InterPro:IPR004106" FT /db_xref="UniProtKB/TrEMBL:O05748" FT /protein_id="CAC31182.1" FT /translation="MTKTSRGTPVPPIAKRVETRRERHGDVFFDPYEWLRDNNNPEVVA FT YLDAENDYVNQMTAHLEPLQQKIFNEIKARTKENDLSVPTRQANWWYYSRTFEGKQYRV FT QCRCPVASPDDWTPPALYENTEISGEQVLLDSNAEAEGHAFFALGTFMVSLDSNLLAYS FT VDFVGDERYTLRFKDLRTGERYPDEIVGIGAGATWAADNRTVYYLTLDESRRPDTVWRC FT RLGSGQPSEQVYHEADERFWLAVGLSRSEAYIFIAAGSAITSEWRYADSTNPDAQFTVV FT LPRRDGIEYSVEHAPSGLVGGQDRFLILHNDGAVNFTLVESPVSNPEQQRTLIPHRDDV FT RLDSADAFAGYLVVSYRREALPRVQLWPIDPDGSYGEPEEISFESELMWVSLEANSNWV FT SPKLRIRAGSFVTPVRVYDVDLATGERTLLREQPVLGGYKHEDYVERREWAQADDGTWI FT PVSIVHRAAIRFPAPAVLYGYGAYEICVDPSFSIPRLSLLDRGMMFVIAHVRGGGEMGR FT LWYEHGKLLEKKNTFTDFISVAKHLVDSGQTRSQELVALGGSAGGLLMGVVANIAPDLF FT TGILAQVPFVDPLTTMLDPSLPLTVTEWDEWGNPLIDSDFYSYIKSYSPYENVEAKQYP FT AILAMTSLHDTRVHYVEPAKWIAALRHTKSDGNPVLLKTQMAAGHAGISGRYKAWQETA FT FQYAWLLAAVDVDQYGTATEVDDLGGGAQG" FT misc_feature complement(295493..295732) FT /note="Pfam match to entry PF00326 Peptidase_S9, Prolyl FT oligopeptidase family, score 93.20, E-value 1.5e-27" FT CDS complement(297181..298074) FT /transl_table=11 FT /gene="purC" FT /gene_synonym="ML2227" FT /product="phosphoribosylaminoimidazole-succinocarboxamide" FT /note="Similar to Mycobacterium tuberculosis FT phosphoribosylaminoimidazole-succinocarboxamide synthase FT PURC OR RV0780 OR MTCY369.24 SW:PUR7_MYCTU (Q59566; P77904) FT fasta scores: E(): 0, 81.5% id in 297 aa, and to FT Haemophilus influenzae putative FT phosphoribosylaminoimidazole-succinocarboxamide synthase FT PURC OR HI1726 SW:PUR7_HAEIN (P43851) fasta scores: E(): 0, FT 46.0% id in 287 aa, and to Candida maltosa FT phosphoribosylamidoimidazole-succinocarboxamide synthase FT ADE1 SW:PUR7_CANMA (P27602) fasta scores: E(): 0, 45.1% id FT in 288 aa. Contains Pfam match to entry PF01259 FT SAICAR_synt, SAICAR synthetase. Contains PS01057 SAICAR FT synthetase signature 1. Contains PS01058 SAICAR synthetase FT signature 2." FT /db_xref="GOA:O08361" FT /db_xref="InterPro:IPR001636" FT /db_xref="InterPro:IPR013816" FT /db_xref="InterPro:IPR018236" FT /db_xref="UniProtKB/Swiss-Prot:O08361" FT /protein_id="CAC31183.1" FT /translation="MRPALFDYRHLASGKVREIYRIDDEHLLMVASDRISAFDYVLDST FT IPDKGRILTAMSVFFFSFVDAPNHLAGPPDDPRIPEEVLGRALVVRQLDMLPMECVARG FT YLTGSGLLDYQATGKVCGIPLPPGLVEASRFAAPLFTPAMKAVLGEHDENISFSRMIEM FT VGVVRANQLRDRTLQIYLQAADHALKTGIIIADTKFEFGIDRDGNLLLADEIFTPDSSR FT YWSVDDYRVGVVQRSFDKQFVRNWLVSPESGWVRAGALSPPSLPDDIIEATRLCYVEVY FT ERISGMSFDDWIGPGA" FT misc_feature complement(297268..298056) FT /note="Pfam match to entry PF01259 SAICAR_synt, SAICAR FT synthetase, score 535.90, E-value 2.7e-157" FT misc_feature complement(297469..297495) FT /note="PS01058 SAICAR synthetase signature 2" FT misc_feature complement(297748..297792) FT /note="PS01057 SAICAR synthetase signature 1" FT CDS 298140..298760 FT /transl_table=11 FT /gene="ML2228" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 21.6 kda protein cy369.23c precursor RV0779C OR MTCY369.23C FT TR:P71833 (EMBL:Z80226) fasta scores: E(): 0, 67.2% id in FT 204 aa." FT /db_xref="UniProtKB/TrEMBL:O05747" FT /protein_id="CAC31184.1" FT /translation="MNSRFLPYATSPGRLTIQLLSDIAVVMWTTFWVLVGIAVYNTIST FT IADTGAQVESGAHGIADNLASASHGMQLIPVLGNAVSKPLTLTSAAALDIADAGHSLNT FT TASWLAVLLALAVIALPILVAVVPWLVLRFWFFRHKWTVTTLAATPAGKQLLALRALTL FT RSPSKLAAVSADPVGGWRREDPGTIRGLAALELQSSGITLRVH" FT CDS complement(298764..299633) FT /pseudo FT /transl_table=11 FT /gene="ML2229" FT /product="similar linalool 8-monooxygenase, cytochrome FT p-450 (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0778 (Best blastx score 305)" FT CDS complement(299673..301091) FT /transl_table=11 FT /gene="purB" FT /gene_synonym="ML2230" FT /product="adenylosuccinate lyase" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 51.0 kda protein cy369.21b RV0777 OR MTCY369.21B TR:P71832 FT (EMBL:Z80226) fasta scores: E(): 0, 86.4% id in 472 aa, and FT to Saccharomyces cerevisiae adenylosuccinate lyase ADE13 OR FT YLR359W OR L8039.12 SW:PUR8_YEAST (Q05911) fasta scores: FT E(): 0, 34.5% id in 449 aa. Contains Pfam match to entry FT PF00206 lyase_1, Lyase. Contains PS00163 Fumarate lyases FT signature." FT /db_xref="GOA:Q9CBC1" FT /db_xref="HSSP:1DOF" FT /db_xref="InterPro:IPR000362" FT /db_xref="InterPro:IPR004769" FT /db_xref="InterPro:IPR008948" FT /db_xref="InterPro:IPR019468" FT /db_xref="InterPro:IPR020557" FT /db_xref="UniProtKB/TrEMBL:Q9CBC1" FT /protein_id="CAC31186.1" FT /translation="MSIPNVLAARYASAELVAIWSPEARVIAERQLWLAVLRAQAELSV FT PMPVKAIADYERVLGEVDLASIAARERVLRHDVKARIEEFNALAGHEQVHKGMTSRDLT FT ENVEQLQIRRSLELVFCHGVAVVARLAECAVSYRDLVMAGRSHNVAAQATTLGKRFASA FT TQETLIALTRLRELIDRYPLRGIKGPMGTGQDMLDLLGGDAAALAELEQRIAEFLGFTK FT VLASVGQVYPRSLDHDVISALVQLGAGSSSLAHTIRLMAGHELVTEGFAPGQVGSSAMP FT HKMNSRSCERVNGLQVVLRGYAAMAAELAGAQWNEGDVFCSVVRRVALPDSFFAIDGQI FT ETFLTVLDEFGAYPAVIRRELDRYLPFLATTKVLIAAVRAGMGREAAHHVIREHAVATA FT LAMRECGAEPDLLDRLAADGRLPLDRAALDAALADKKAFTGAAADQVDEVVAMVDKLVG FT RYPEAAKYTPGAIL" FT misc_feature complement(299820..300893) FT /note="Pfam match to entry PF00206 lyase_1, Lyase, score FT 53.50, E-value 4e-14" FT misc_feature complement(300237..300266) FT /note="PS00163 Fumarate lyases signature" FT CDS 301170..301935 FT /pseudo FT /transl_table=11 FT /gene="ML2231" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0776c (Best blastx score 364)" FT CDS complement(302075..302700) FT /pseudo FT /transl_table=11 FT /gene="ML2232" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0775 (Best blastx score 161)" FT CDS 302736..303655 FT /pseudo FT /transl_table=11 FT /gene="ML2233" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0774c (Best blastx score 391)" FT CDS 303877..305356 FT /pseudo FT /transl_table=11 FT /gene="ggtA" FT /gene_synonym="ML2234" FT /product="putative [gamma]-glutamyl transpeptidase FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT ggtA (Best blastx score 208)" FT CDS complement(305487..306755) FT /transl_table=11 FT /gene="purD" FT /gene_synonym="ML2235" FT /product="phosphoribosylamine-glycine ligase" FT /note="Similar to Mycobacterium tuberculosis FT phosphoribosylamine--glycine ligase PurD OR RV0772 OR FT MTCY369.17 SW:PUR2_MYCTU (P71827) fasta scores: E(): 0, FT 81.8% id in 418 aa, and to Salmonella typhimurium FT phosphoribosylamine--glycine ligase PurD SW:PUR2_SALTY FT (P26977) fasta scores: E(): 0, 43.2% id in 426 aa. Contains FT Pfam match to entry PF01071 GARS, Phosphoribosylglycinamide FT synthetase (GARS). Contains PS00184 FT Phosphoribosylglycinamide synthetase signature." FT /db_xref="GOA:Q50144" FT /db_xref="InterPro:IPR000115" FT /db_xref="InterPro:IPR011054" FT /db_xref="InterPro:IPR011761" FT /db_xref="InterPro:IPR013815" FT /db_xref="InterPro:IPR013816" FT /db_xref="InterPro:IPR013817" FT /db_xref="InterPro:IPR016185" FT /db_xref="InterPro:IPR020559" FT /db_xref="InterPro:IPR020560" FT /db_xref="InterPro:IPR020561" FT /db_xref="InterPro:IPR020562" FT /db_xref="UniProtKB/Swiss-Prot:Q50144" FT /protein_id="CAC31191.1" FT /translation="MRVLVIGSGAREHALLLALSRDPQVKGLVVAPGNAGTARLAEQYD FT VDISSGEDIVALARDVRADMVVIGPELPLVLGVADAVRAAGIVCFGPSKDAARIEGSKA FT FAKEVMAAAGVRTSRSEIVNSPARLDAALDRFGPPVGDLSWVVKDDRLAAGKGVVVTSD FT RDVARTHAAGLLEAGHPVLLESYLDGPEVSLFCVVDGRTVLPLLPAQDFKRVGEGDTGP FT NTGGMGAYAPLPWLPDEVCQQALTSIVEPVAAELVQRGSPFRGLLYVGLAVTASGPAVV FT EFNCRFGDPETQVVLALLDSPLGQLLYAAGTGSLADFGELHWRSGAAVAVVLAAENYPR FT RPRVGDIVFGSEIEGVLHAGTTRRDDGVIVSSGGRVLSVVATGDDLSAARSQAYRIIGS FT IRLLGSHFRKDIGFSAAKGRIHI" FT misc_feature complement(305508..306743) FT /note="Pfam match to entry PF01071 GARS, FT Phosphoribosylglycinamide synthetase (GARS), score 799.80, FT E-value 1e-236" FT misc_feature complement(305877..305900) FT /note="PS00184 Phosphoribosylglycinamide synthetase FT signature" FT repeat_region complement(307750..308502) FT /note="753 bp repeat, 100% identical to region FT 1293273..1294025" FT CDS 307752..308506 FT /pseudo FT /transl_table=11 FT /gene="ML2236" FT /product="REP13E12-family protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv0094c (Best blastx score 229)" FT CDS 308596..309000 FT /transl_table=11 FT /gene="ML2237" FT /product="conserved hypothetical protein (HIT family)" FT /note="Similar to Mycobacterium leprae hypothetical 14.7 FT kda protein MLCB5.04C TR:Q9R734 (EMBL:Z95151) fasta scores: FT E(): 0, 100.0% id in 134 aa, and to Borrelia burgdorferi FT hypothetical 15.9 kda hit-like protein PKCI OR BB0379 FT SW:YHIT_BORBU (P94252) fasta scores: E(): 5.2e-11, 42.3% id FT in 111 aa. Contains Pfam match to entry PF01230 HIT, HIT FT family. Contains PS00892 HIT family signature." FT /db_xref="GOA:P49774" FT /db_xref="InterPro:IPR001310" FT /db_xref="InterPro:IPR011146" FT /db_xref="InterPro:IPR011151" FT /db_xref="InterPro:IPR019808" FT /db_xref="UniProtKB/Swiss-Prot:P49774" FT /protein_id="CAC31193.1" FT /translation="MATIFTKIINRELPGRFVYEDDDVVAFLTIEPMTQGHTLVVPCAE FT IDQWQNVDPAIFGRVIAVSQLIGKGVCRAFNAERAGVIIAGFEVPHLHIHVFPTHSLSN FT FSFANVDRNPSPESLDAAQDKIKAALTQLA" FT misc_feature 308602..308892 FT /note="Pfam match to entry PF01230 HIT, HIT family, score FT 156.50, E-value 4.6e-43" FT misc_feature 308833..308889 FT /note="PS00892 HIT family signature" FT CDS complement(309079..310421) FT /pseudo FT /transl_table=11 FT /gene="phoR" FT /gene_synonym="ML2238" FT /product="sensor histidine kinase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT phoR (Best blastx score 378)" FT CDS complement(310488..311194) FT /pseudo FT /transl_table=11 FT /gene="phoP" FT /gene_synonym="ML2239" FT /product="two-component response regulator (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT phoP (Best blastx score 386)" FT CDS 311376..311810 FT /pseudo FT /transl_table=11 FT /gene="ML2240" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0756c (Best blastx score 180)" FT tRNA 311842..311916 FT /gene="thrV" FT /note="tRNA Thr anticodon TGT, Cove score 85.47" FT CDS complement(311952..312987) FT /pseudo FT /transl_table=11 FT /gene="PE_PGRS" FT /gene_synonym="ML2241" FT /product="PE_PGRS-family protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT PE_PGRS (Best blastx score 185)" FT CDS complement(313194..313925) FT /transl_table=11 FT /gene="ML2242" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium fortuitum plasmid pAL5000 FT hypothetical 26.6 kda protein TR:Q52145 (EMBL:M23557) fasta FT scores: E(): 9.9e-05, 27.2% id in 250 aa." FT /db_xref="GOA:Q50153" FT /db_xref="InterPro:IPR009003" FT /db_xref="UniProtKB/TrEMBL:Q50153" FT /protein_id="CAC31198.1" FT /translation="MRSIYWFTGETCATVRWLRGLGLASAAVIAPKVFASMVLAEYAPS FT PGLRLCDESSICTAACVARGNDGSSYLLTIGHCDAYDGSVWPYGPDVPLGKRTVSENEG FT DRKDAAIILLDLSQGYSSGDVYSQLLRNVLSENEIQLGMLFCKVGAITGETCGTIKSMD FT GDVVEASVYSLSAGSGSPGFVKNVDGIVSAVGILMSSPEGDDHTTYFVPMPPLLEKRGL FT QSFPEVLKRLSPRLVGWGSGS" FT CDS complement(318857..319144) FT /pseudo FT /transl_table=11 FT /gene="ML2243" FT /product="PPE-family protein (pseudogene)" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT PPE-family protein rv3425 RV3425 OR MTCY78.04C FT SW:YY25_MYCTU (Q50703) fasta scores: E(): 1.3, 30.7% id in FT 101 aa" FT CDS complement(319373..319714) FT /transl_table=11 FT /gene="ML2244" FT /product="hypothetical protein" FT /note="no database matches." FT /db_xref="UniProtKB/TrEMBL:Q9CBC0" FT /protein_id="CAC31200.1" FT /translation="MSFVVVNTSALCQSAFDLKNFSEEMREIKDTAIIGLVLLANDCVS FT KLVASSLHEHFTQQNPLRSRRFLTCSDLNLLLRVEAYEDPRTTRPKTSTDVTEDDTGIA FT NIDTSAGSR" FT CDS complement(319940..320533) FT /pseudo FT /transl_table=11 FT /gene="ML2245" FT /product="sarcosine oxidase (pseudogene)" FT /note="Similar to Streptomyces sp sarcosine oxidase FT SW:SAOX_STRSQ (P40854) fasta scores: E(): 4e-14, 34.8% id FT in 204 aa" FT CDS complement(321482..322152) FT /pseudo FT /transl_table=11 FT /gene="ML2246" FT /product="unknown membrane protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3482c (Best blastx score 128)" FT CDS 322472..324022 FT /transl_table=11 FT /gene="cpsA" FT /gene_synonym="ML2247" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis cpsa CPSA OR FT RV3484 OR MTCY13E12.37 TR:O06347 (EMBL:Z95390) fasta FT scores: E(): 0, 74.9% id in 518 aa, and to Streptococcus FT agalactiae cpsx protein CPSX TR:Q9S2Z3 (EMBL:Y17241) fasta FT scores: E(): 1.9e-09, 26.0% id in 254 aa, and to FT Streptomyces coelicolor putative transcriptional regulator FT SC6G4.33 TR:O86796 (EMBL:AL031317) fasta scores: E(): FT 4.6e-09, 27.2% id in 327 aa." FT /db_xref="InterPro:IPR004474" FT /db_xref="UniProtKB/TrEMBL:Q50160" FT /protein_id="CAC31203.1" FT /translation="MARSHNPRHRHRAIHKPSRIRIALTRSFMTLTSFVAVLLTGAGYW FT VAHRALEDITVSQALTTDDPRSTDNNINILLIGLDSRKDQQGNDLPWSILKQLHAGDSN FT DGGYNTNTLILVHVGADNKAVAFSIPRDDWVPFSDVPGYNHIKIKEAYGLTKQYVTQKL FT IDQGVTDQKELETQGREAGRAATLRIVRSLTGVSIDYFAEVNLAGFYDLTHTLGGVEVC FT LNHAVYDSYSGADFPAGRQRLDASEALAFVRQRHGLDNGDLDRTHRQQAFISSVMRELG FT DTGTFTNLDKLRSLMAVARKDVVLSAGWNEDLIQRLGTLANDVGENRTQFRTLPVVRYD FT NINGQAVNIIDPVAIKAEVASTIGTASPATATPSKPNPSTVVDVINAGRLTGLASEVFQ FT TLKKHGYTAGQVRDRSSGEPTTTSIQYGAGADTDAQNVATLLSIDAPNQADPKLASGHI FT RVIVDTNYSLPADEDSTMDETITSQKVGTYPPYSYNTSPYPTPDQGKPIDGGGIPCVN" FT CDS complement(324287..324835) FT /pseudo FT /transl_table=11 FT /gene="ML2248" FT /product="probable fatty-acyl CoA reductase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv1543 (Best blastx score 301)" FT CDS complement(324870..325187) FT /transl_table=11 FT /gene="ML2249" FT /product="hypothetical protein" FT /note="no database matches." FT /db_xref="UniProtKB/TrEMBL:Q9CBB9" FT /protein_id="CAC31205.1" FT /translation="MLDEIIGWRQGLAKFTILSWPNAMSSTGPIVGEHRENNRTTAGFG FT CVPPSRLAERGIPPLSGEPVVDGDLVTGFQQLGSHAAAHAPQADKLDVHVIHHAGFSEA FT W" FT CDS complement(325799..326575) FT /pseudo FT /transl_table=11 FT /gene="ML2250" FT /product="short-chain alcohol dehydrogenase family FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3485c (Best blastx score 284)" FT CDS complement(326724..327492) FT /pseudo FT /transl_table=11 FT /gene="echA13" FT /gene_synonym="ML2251" FT /product="enoyl-CoA hydratase/isomerase superfamily FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT echA13 (Best blastx score 169)" FT CDS complement(327917..328153) FT /transl_table=11 FT /gene="ML2252" FT /product="hypothetical protein" FT /note="no database matches." FT /db_xref="UniProtKB/TrEMBL:Q50165" FT /protein_id="CAC31208.1" FT /translation="MTRAVSAWVAKRVNFASHRKEGRTIASVHDRYDMERMAIRVVADT FT LGNTIPETGYERLCRSDIDNDGSAVASEQILPN" FT CDS complement(328469..328684) FT /transl_table=11 FT /gene="ML2253" FT /product="antigen 84 homolog" FT /note="Similar to Mycobacterium tuberculosis antigen 84 FT AG84 OR WAG31 OR RV2145C OR MTCY270.23 SW:AG84_MYCTU FT (P46816) fasta scores: E(): 2.2e-05, 50.0% id in 54 aa, and FT to Mycobacterium leprae antigen 84 AG84 SW:AG84_MYCLE FT (P46815) fasta scores: E(): 5.4e-05, 48.1% id in 54 aa." FT /db_xref="UniProtKB/TrEMBL:Q50166" FT /protein_id="CAC31209.1" FT /translation="MPNNIAFSRSYIGKRCYSEQEVGVFIDLAEQERTRHIEEDVEFRN FT RNAELRNQDGAPQPRSCADRARNCHV" FT CDS 329413..330909 FT /transl_table=11 FT /gene="otsA" FT /gene_synonym="ML2254" FT /product="probable trehalose-phosphate synthase" FT /note="Similar to Mycobacterium tuberculosis otsA or Rv3490 FT or MTCY13E12.43 TR:O06353 (EMBL:Z95390) (500 aa) fasta FT scores: E(): 0, 80.3% id in 497 aa. Similar to Candida FT albicans alpha,alpha-trehalose-phosphate synthase FT [UDP-forming] tps1 SW:TPS1_CANAL (Q92410) (478 aa) fasta FT scores: E(): 0, 37.8% id in 473 aa. Previously sequenced as FT TR:Q50167 (EMBL:U15187). Contains Pfam match to entry FT PF00982 TrehaloseP_syn, Trehalose-6-phosphate synthase FT domain." FT /db_xref="GOA:Q50167" FT /db_xref="HSSP:1GZ5" FT /db_xref="InterPro:IPR001830" FT /db_xref="UniProtKB/Swiss-Prot:Q50167" FT /protein_id="CAC31210.1" FT /translation="MTSRGNHGSKTSSDKHLGDSDFVVVANRLPVDQVRLPDGTAIWKR FT SPGGLVTALEPLLRQRRGAWVGWPGVINDNVDLDLTIKSIVQDGLTLYPVRLNTHDVAE FT YYEGFSNATLWPLYHDVIVKPIYHCEWWERYVDVNRRFAETTSRTAAYGGTVWVQDYQL FT QLVPKMLRIMRPDLTIGFFLHIPFPPVELFMQIPWRTEIIEGLLGADLVGFHLTSGAQN FT FLFLSRHLLGANTSRGLVGVRSRFGEVQLKSHTVQVGAFPISIDSKEIDQATRDRNVRR FT RAREIRAELGNPRKILLGVDRLDYTKGIDVRLRAFAELLAEGRAKRDDTVLVQLATPSR FT ERVESYKILRNDIERQVGHINGEYGEVGHPVVHYLHRPIPRDELIAFYVASDVMLVTPL FT RDGMNLVAKEYVACRNDLGGALVLSEFTGAAAELRQAYLVNPHDLEGVKDTIEAALNQL FT AEEARRRMRSLRRQVLAHDVDRWARSFLDALAEAPARDAT" FT misc_feature 329470..330885 FT /note="Pfam match to entry PF00982 TrehaloseP_syn, FT Trehalose-6-phosphate synthase domain, score 771.20, FT E-value 4.1e-228" FT CDS 331013..331572 FT /pseudo FT /transl_table=11 FT /gene="ML2255" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3491 (Best blastx score 304)" FT repeat_region complement(331612..332458) FT /note="Dispersed repeat, RLEP, copy 34 " FT CDS complement(332474..333471) FT /pseudo FT /transl_table=11 FT /gene="ML2256" FT /product="unknown membrane protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0541c (Best blastx score 212)" FT CDS complement(333527..334633) FT /transl_table=11 FT /gene="menE" FT /gene_synonym="ML2257" FT /product="o-succinylbenzoic acid-CoA ligase" FT /note="Similar to Mycobacterium tuberculosis MenE or FT RV0542C or MTCY25D10.21C TR:O06408 (EMBL:Z95558) fasta FT scores: E(): 0, 78.3% id in 359 aa, and to Escherichia coli FT o-succinylbenzoic acid--coa ligase MENE SW:MENE_ECOLI FT (P37353; P78253; P78178) fasta scores: E(): 7e-18, 30.0% id FT in 377 aa. Contains Pfam match to entry PF00501 FT AMP-binding, AMP-binding enzyme. Contains PS00455 Putative FT AMP-binding domain signature." FT /db_xref="GOA:Q9CBB8" FT /db_xref="InterPro:IPR000873" FT /db_xref="InterPro:IPR020845" FT /db_xref="UniProtKB/TrEMBL:Q9CBB8" FT /protein_id="CAC31213.1" FT /translation="MLLPTLERILDGRAPAMVVVPAQHEPIAALRALRVGEEIDDDVAL FT VATTSGTTGVPKGALLTAAALTASASATHDRLGGPGSWLLALPPYHIGGLQVLVRSVLA FT GSVPIELDISAGFDLAKLPDAVGRLGTGRRYTSLVATQLAKALTDSTATAVLAELDAVL FT VGGGPAPRPILDAATSAGIMVVGTYGMSETAGGCVYDGVPLDGVCIRVLVNGHVAIGGA FT TLAKGYRNPIVPDPFAESGWFHTDDLGTVDGSGVLTVLGRADDAISTGGLTVLPGPVEA FT ALCTHPAVSDCAVFGLTDDRLGQRVVAAVVLTDGYATPTLSMLRAHVTRRLDAMAAPRE FT LHIVDTLPRRGIGKVDRTALVRRFAKSG" FT misc_feature complement(333752..334633) FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score -134.30, E-value 6.3e-08" FT misc_feature complement(334463..334498) FT /note="PS00455 Putative AMP-binding domain signature" FT CDS complement(334678..334980) FT /transl_table=11 FT /gene="ML2258" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 11.3 kda protein RV0543C OR MTCY25D10.22C TR:O06409 FT (EMBL:Z95558) fasta scores: E(): 1.4e-27, 73.5% id in 98 FT aa, and to Mycobacterium tuberculosis hypothetical 13.4 kda FT protein RV3046C OR MTV012.61C TR:O53292 (EMBL:AL021287) FT fasta scores: E(): 6.8e-07, 35.9% id in 103 aa." FT /db_xref="UniProtKB/TrEMBL:Q50171" FT /protein_id="CAC31214.1" FT /translation="MNRFLTSIVSWLRAGYPEGIPATDTFAVLALLARRLTNDEVKLVA FT RELIRRGEFDKIDIGVMISHLTDELPSPQDIERVRTRLNAKGWLLDNARDNGEPT" FT CDS complement(335010..335300) FT /transl_table=11 FT /gene="ML2259" FT /product="possible membrane protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 9.7 kda protein RV0544C OR MTCY25D10.23C TR:O06410 FT (EMBL:Z95558) fasta scores: E(): 3.3e-22, 64.6% id in 96 FT aa. Contains possible membrane spanning hydrophobic FT domains." FT /db_xref="UniProtKB/TrEMBL:Q9CBB7" FT /protein_id="CAC31215.1" FT /translation="MSPWFNYEATLKILLFSTLAGAALPGLFALGIRLQVNDAGDASTN FT NATPHRKPILVTLAWVIYALVLMVVILGVLYIVSRDFIAHHTHYPFLGIKP" FT CDS complement(335297..336541) FT /transl_table=11 FT /gene="pitA" FT /gene_synonym="ML2260" FT /product="low-affinity inorganic phosphate transporter" FT /note="Similar to Mycobacterium tuberculosis probable FT low-affinity inorganic phosphate transporter PIT OR PITA OR FT RV0545C OR MTCY25D10.24C SW:PIT_MYCTU (O06411) fasta FT scores: E(): 0, 76.3% id in 418 aa, and to Bacillus FT subtilis probable low-affinity inorganic phosphate FT transporter PIT SW:PIT_BACSU (O34436) fasta scores: E(): 0, FT 43.9% id in 312 aa. Contains Pfam match to entry PF01384 FT PHO4, Phosphate transporter family. Contains possible FT membrane spanning hydrophobic domains." FT /db_xref="GOA:Q50173" FT /db_xref="InterPro:IPR001204" FT /db_xref="UniProtKB/Swiss-Prot:Q50173" FT /protein_id="CAC31216.1" FT /translation="MNINLFLLIIVVITALAFDFTNGFHDTGNAMATSIASGALAPKVA FT VFFSAILNLVGAFLSTAVAATIAKDLIEADLVTLELVFAGLVGGIVWNLLTWLLGIPSS FT SSHALIGGIVGARIAAVGGHGVIWSGVISKVIIPAIIAALLAIVVGAVATWLVYAITRS FT VPAMSTDTRFRRGQIGSASLVSLAHGTNDAQKTMGVIFLALMSYGTVSKTASTPPLWVI FT VCCAIAIAAGTYLGGWRIIRTLGKGMVEIKPPQGMAAESSSAAVILLSAHFGYALSTTQ FT VCTGSVLGSGLGKPGGEVRWGVAGRMATAWLVTLPLAGSVGAVTYWIVHLIGGYPGAVI FT GFSLLVAASVAIYIRSRKVKVDHKNVNENWEGSLTAGLDGSDEHKPHSDVGPKLSATLP FT RYRSSHHTVGVRNAS" FT misc_feature complement(335576..336478) FT /note="Pfam match to entry PF01384 PHO4, Phosphate FT transporter family, score 90.40, E-value 3.6e-23" FT CDS complement(336639..337055) FT /transl_table=11 FT /gene="ML2261" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT 14.3 kda protein RV0546C OR MTCY25D10.25C TR:O06412 FT (EMBL:Z95558) fasta scores: E(): 0, 84.7% id in 131 aa. FT Also some similarity to Haemophilus influenzae FT lactoylglutathione lyase GLOA OR HI0323 SW:LGUL_HAEIN FT (P44638) fasta scores: E(): 0.084, 29.1% id in 127 aa." FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/TrEMBL:Q9CBB6" FT /protein_id="CAC31217.1" FT /translation="MEILASRMLLRPTDYQRSLSFYRDQIGLAIAREYGTGTVFFAGQS FT LLELAGYVIQGAPDHSRGAFPGALWLQVRDIAVTQADLEGRGVSITREPRREPWGLHEM FT HVTDPDEITLIFVEVPANHPLRRDTRSERPRTPD" FT CDS complement(337803..338616) FT /pseudo FT /transl_table=11 FT /gene="ML2262" FT /product="putative oxidoreductase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0547c (Best blastx score 587)" FT CDS complement(338709..339611) FT /transl_table=11 FT /gene="menB" FT /gene_synonym="ML2263" FT /product="naphthoate synthase" FT /note="Similar to Mycobacterium tuberculosis MenB or FT RV0548C or MTCY25D10.27C TR:O06414 (EMBL:Z95558) fasta FT scores: E(): 0, 91.9% id in 308 aa, and to Bacillus FT subtilis naphthoate synthase MENB SW:MENB_BACSU (P23966) FT fasta scores: E(): 0, 50.4% id in 270 aa. Contains Pfam FT match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase FT family." FT /db_xref="GOA:Q9CBB5" FT /db_xref="HSSP:1MJ3" FT /db_xref="InterPro:IPR001753" FT /db_xref="InterPro:IPR010198" FT /db_xref="UniProtKB/TrEMBL:Q9CBB5" FT /protein_id="CAC31219.1" FT /translation="MSNNPFDAKLWRLIDGFGDLTDITYHRYVNGATVRVAFNRPEVRN FT AFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPRDGVWAFCSGGDQRIRGRSGYQYA FT SGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVICDLTLASRE FT HARFKQTDADVGSFDGGYGSAYLARQIGQKFAREIFLLGRAYTAEQMHHMGAVNAVAEH FT ANLETMGLEWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEG FT RDAFLQKRAPDWSSFPRYF" FT misc_feature complement(338949..339512) FT /note="Pfam match to entry PF00378 ECH, Enoyl-CoA FT hydratase/isomerase family, score 128.40, E-value 1.3e-34" FT CDS complement(339608..340219) FT /transl_table=11 FT /gene="ML2264" FT /product="hypothetical protein" FT /note="Unknown function." FT /db_xref="UniProtKB/TrEMBL:Q9CBB4" FT /protein_id="CAC31220.1" FT /translation="MRKVSDRAAHLPQLAWPSARSTISTATTARTRYELSLLWCWRCQP FT NRWCHHPRGANIDVQMSSARPIPMRTWVISTQNDGGHQIIDSHGRGARLYTFVDYRLQT FT VVDTLAAPFLFFLQNVRYRSIGVNYRDLGGDRQLVGLQALEKTSQWTVRRTTIDLAGTL FT ASISRSDTVTTTSAHDAVVTSAQTISCGDLTTNQDGVQEP" FT CDS complement(340212..340433) FT /transl_table=11 FT /gene="ML2265" FT /product="hypothetical protein" FT /note="Unknown function." FT /db_xref="UniProtKB/TrEMBL:Q9CBB3" FT /protein_id="CAC31221.1" FT /translation="MPSLDQHTWTLPDGGADAEDAKPLLRVWPSEVPTGVGCMKQFKLV FT NGGLTEKVEMLTGICPVVRFDSARFFFA" FT CDS complement(340725..342228) FT /pseudo FT /transl_table=11 FT /gene="fadD8" FT /gene_synonym="ML2266" FT /product="acyl-CoA synthase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT fadD8 (Best blastx score 345)" XX SQ Sequence 342300 BP; 78514 A; 102180 C; 92490 G; 69116 T; 0 other; tcccagtctg gataccctga tcggcgcaac attcactcca aaacttataa cgtgagccga 60 taactggaaa ttccagaact gaacacgcaa aaagtcgtcg cgatgaagca ccgtttgccc 120 tacaataccc cgtcattcgg cttcaccaaa attgtcgcta aatgcacggc accgggtgga 180 ataggaccgg agtaagggca gcatgccgtc gggtggtgtc caccatgacc gactctagat 240 acccgtgctc gtgccagtgt taaagccaac aatactagtc tacgccgtgg tcgcctatga 300 cactccgtac gcgatcgcag tgcatcggcg ccagcacttc gagaccagcg ccgaccacgt 360 ccctgtttaa gtcctcacct aaaaggagga tcacctggct tcagcactgg ccgaactgac 420 agggccgctc tgactgattc acctgtgacc aggcccttac ctggttaacg ttccgctagg 480 gtttgaccat gcggttattg gtcaccggcg gagcgggctt tatcggagcc aattttgtgc 540 ataacgcggt gcgcgaccat cccgacgata cggtgacggt gctagacgcc atgacttacg 600 caggcagaca cgagtcgctg gccgatgtcg accatgctgt caggctggtg caaggcaata 660 tcaccgacac caagctggtt ttccgactgg tcgccgagtc cgacgtggtt gtgcatttcg 720 ccgccgaaac ccatgtggac aacgcgctcg acgacccaga accgttccta cgcaccaacg 780 tcatcgggac gttcaccatc ctggaggcag tgcgacacca cagtgtgcgg ctgcaccaca 840 tctcgaccga cgaagtctat ggcgacctag agctcgacga accaacaagg tttactgagt 900 caacgcccta caacccgtcg agtccgtact cggcaaccaa agccgccggc gacatgttgg 960 tccgggcttg ggtgcgctcc tacggcgtgc gtgcgacgat ttccaactgc tccaacaact 1020 acggaccata ccagcacgtc gaaaagttca ttccgcgcca aatcaccaat gtgctcaccg 1080 gccgccggcc caagttatac ggcaccggcg tcaacgtccg cgactggatc cacgtcgacg 1140 accacaacag cgccgtctgg caaatcctcg agaaaggcca gataggccgc acttacctca 1200 tcggagccga aaacgggcat aacaacctga ccgtgttgcg cacactgcta cagatgatgg 1260 gccgagaccc caacgatttc gaccatgtca ccgaccgcgt cggccacgac ttacggtacg 1320 cgatcgaccc aacaccgctg tacaacgaat tatgctgggc tccaaagcac gccaacttcg 1380 acgagggatt gcgcgccacc attgactggt atcggaacaa cgaatcgtgg tggagaccgt 1440 tgaaggacgc cgtggaagcg cgctacgaag aacgaggtcg gtgaaatgaa cgtcaaagaa 1500 ctggatatct cgggcgcctg ggagatcacc cctactattc atagcgattc ccgcggaatg 1560 tttttcgaat ggctcacagc cagtaggttc agcgcattca ccggtcaccg cttagacgtc 1620 cggcaagcca actgctcggt gtcctcggcc ggtgtgttgc ggggcctgca tttcgctcaa 1680 gtgccaccga gccaggccaa atatgttacc tgcgtgaccg gttcggtgtt cgatgtcgta 1740 gtcgatatcc gtttaggatc accaacattc ggctgttgga cctcaattac gctcaacgac 1800 tccaaccgga agaccattta tatctccgag agtctcgcac acggattcct tgcactgcaa 1860 gataattcta cagttatgta cctatgctct gctgaataca accctgcgcg cgaacacgcc 1920 atctgcgcca cggatccgga cctggcaatc gactggccgg tggtcgacgg tgttgacacg 1980 cacttgtcca agcgtgatgc cacagccccc aatcttgatg acatacgcgc gtctggacta 2040 ctgccgacct gggatgaaac gcagaatttt atcgccaacc tcggcagcaa atagcaacgc 2100 ggccatcaca agttactacc gacataagga gaattttggt gaggcataag ttattggccg 2160 ccatctacgc cgtcacgatc atggccggcg cggcgggctg cagcgggggc acgcaggctc 2220 ccaccccttc ggtgagcaaa accacaaact ccagccccac aaccgtagcg agcagcattc 2280 ccgacgcagc agccggagaa acgaaggtca ccatcggcgg ccagccacaa aaagtcagtg 2340 gcccggtcgt gtgctcaact acaaacggca agttctcgat cgcgatcggt gacatgatca 2400 ccggagtcat cgttggcttg gagccggacg catcggtggt ccataacgcc ggcctcggca 2460 ccatagacgg tgtggtcata gccttcaccg agggcgtccc cagcgagaac gccaatgcca 2520 ccaaaaacgg caacacatac caaatcaccg gtacagccag cggtgtagac aataccggcc 2580 agcagatcca taagtctttc gaaatcgaag tcacctgccg ctaacaccgg ttgccgaacc 2640 tcgccacctg gtcaccaacc ggccggcccc tgagcaaatt tgtgcccgtt atcgatctac 2700 ctgggcacga gggcggtgcc ccgggtacac tctcagagag ccacttcaga tcgactccgc 2760 aagatgcccg aaaagttcgg ccatggcagc cgatgtccat gcaggtccaa ttcacgaaca 2820 acagagcaag ccgcacatgg ggctaatcgt tcctaccggc caaccacagc aatagaatga 2880 aaactatact ggcattaggc gacaacgtat tagccttttc gaccacacgg cacgtgtgtg 2940 tatcacgatg tagagctgcg acaacacctt gactgctaag tcgccgaatt tctttatctc 3000 cctatgattt tcatagggag aatgccacag gcgattcatg gcttgctgca tcggtaacca 3060 taagaccttc ggagtcttga tgccaacctg cgcggctgcc gcaccgcttc agagtgcacc 3120 ggtgtaatta cggtatcaac caccgtgaca gttctcacct ggctacacca ccacggcatc 3180 gataccagta tcgtgcgcgt tctcgcatgc cgattaactc accgatctac cggctaccga 3240 aaagacactg ggtcagttaa ggctgtggaa tcaactcaag tatccgcgtt gtcgacggaa 3300 ccaccagcat gactgcttgt tctccttacc agtttgacac caatgacatt ataaccacca 3360 tgcgcgatac ttagctctca agtatattct agcgtcttcg gaggtagtgg gatacatgcc 3420 cgaaatgcta tcaccacatt gagaaagcaa ttccctgggc aggggttgta catgtcgaat 3480 tcgtgtgcag tgtagtggct ttgactcacg ttggatgacc caaaaccatt agcgggtttg 3540 tgataaaccc aatacgcggt tgtcgtagac gcaagctcga gggcactgtt agcactgcta 3600 ctggccaaga gtaacatcgc cgttaccctc gtgaagcacg acgacaagct gattatagca 3660 gccgaagcgt ccacctctca tccatcaacg ttgaatctcc ttagaacact cgtacctgag 3720 cgcacttccg acacctaggc catcaccgtg acctaagtgc agtggcgcta caaccgcaga 3780 gacattcgcg cggaacttga ttaccggtta ctcgccatag tgcaatacta acagcccggg 3840 ttaaacggcc aggaaatcga cattcatggt ctgatagccg ccagcatcgc tacatccttg 3900 cggacgctct cagtggaggt tcctgtagca gtatgctatc aaatcaatta tagtgcaaat 3960 gcttgggcga aaatggtcac taacgttgcg gaaccgcaag cgatagcgtc ggccagccac 4020 aatgtcaggc gctgactgat gtagcatcca ttgcgaacgg agtgcctttg atggtccaga 4080 tgttgaactc attgctgtcg acggtgcttt tctcgatgag catgtcaata acgtaatcga 4140 tcggcgggac gatacggtcc ggtggtggtg acaacggctg ggggcgtggg cgccgcaacg 4200 actagtatat tcgacgacaa tacccatgcc tgcttgatga tcctcgtcgg aaaggtaccc 4260 aagatccagt taccggaatt actcatttcc tttccacgat cgcaggagat gcgttcggta 4320 gcgaccagcc acaacgcttg caccgtaacg ggtttagtca ccaggttgcc atcgagtcat 4380 tatcacggca acggtaaaag gtgtgcctag acagggcaag actgcagttt tcggtggcgc 4440 tgccattgag cacgtgcatc agaacccgct gtcctgattg atacacggat cagatcgcca 4500 tggccaagac tacgaccatt gacggtaaag ggtgtcgtag ccaatctcgt agccgtgcgg 4560 tgttcccaaa gccaacgagt ggccatggcc cactccacgt cgtagcgcaa ctctgtgatc 4620 agggcactaa cgagaaaaaa gctgggcata tcgctggccc agcttgggcc cgaactcctt 4680 aagagttagg aacactttaa ctagtcgtaa gcgctcaact gctccgtttg cgtaaatcac 4740 gtctatgaac gagccgaact ggcatcacct ggctggccgg ctagactgcg gcaaacccct 4800 gaaccaaccc ggtcttatag tgatttccgg cgacttaggc cacgaagtca ccttcgacaa 4860 catattcaac acgtcaattg cataggtgcc cattgcctta gcattccagg cccagaactg 4920 cgtatattgc gcctcgcggg ctacgatcgc caaagcgttc tctccgaaca ggtcggactg 4980 gaccagcccc tgcaatctgg cgcggttact aggcgatcac ctctggagac accacagttt 5040 tacacgctaa aaagcaggcc gcccaccagg cggaaggctt gtttagcggt ccgaaagctt 5100 tcgtggacga acgtatacaa ccattcctga tagaagcaca aacacctcga ccagccggtc 5160 cgctgactga cctgaccacc ccgcattcag cttcgtgagc aattcctgaa caactttagg 5220 ggtgcgagcc atctagttaa acaactactt ccctttttcg gtcgacggca aacagtttgt 5280 taggccccat gccagtatac aggtcgtctc cgacgataac gcctcgaatg cgaaaacatc 5340 tctttgttcg ttattcctta ccgaccggta acgactgctg ctggtatcga agtctgcggt 5400 gcaggtatcg ccttaagtga gatcagacta aaggtttcag cgtgggcttc ccgaggcaat 5460 ttaatatgca gtggagttta tcgccaagac ctctgaaaac tggttaagaa tcgccatgca 5520 tcgagccaga gtctgctgat actgttcggc gtatatcctc aggtaagctc ccgccttctg 5580 caacaacgcg tctatagctg cggccgtaac accgttcaga tccgggaaca cctgggtaat 5640 tagactcaac tacaggagtt ctagtgttgt gtgttggtga ttgttttaac gtttgatttt 5700 gttgaggggg tgtctgcggt ctgggttcag gtgaacggtg tggtgtgttc gttgtaggtg 5760 gggatcgcgg tttcgaggtt gttgatatcg gtgaacgtgt tgtggcgggt gatggtggtg 5820 aagaagattt tggttatgtg tcagctatga gcagcttgtc ggtgtgaagt gcagtgtggc 5880 ttgctggtta tcctgtagcc aggatcggct gctgggggtt tgtgggttgg cgtagttgtc 5940 gcagattggg gcatgcctgt atgtgtgggt gtgttttggt ggcgagtttg aaggtagtgg 6000 cagaatcggt ttgggtgtga tccagctgct tgggtctggg gcttcattgt cgacgctaga 6060 gcataatcgc ggccgcgggt tgagtaggcc tggggcgcgg tgtgggtgta ttactttcgg 6120 tccgtttccc agactggtcg ccgatcctgg tgtgcgcgtc tttgcgcacc gggcttttca 6180 tggtcactac cgttaggcgg tgggaatact ggtccaaggg ttgggtattg tggtgatttg 6240 gtagcggtac cgggtgaccg gtatcgaggt cgggttcaat agggtggtct cttctgcgtc 6300 aatcggtttt caccgttttt cggaggtggt gaactgccgg cgaatgtctt tccatctccg 6360 gcgatacagt gctcgaaacc accgatggtt gatctgtgcc agcacggccc ccggattgcg 6420 ctgtgatttc ctgtttgcca gggcacggat cttggctttg accgaccgtc gtgcccggtc 6480 ggcgatacaa gtcctagaca tgcccacgtg gtcgttgcct tcttgggtgt ccacccggtg 6540 tggaagccgc gaaagtccat accagttacc gaagtgcgcg gtctttgtct ttgcagtcga 6600 cagctgcaga cctagaggcg taagcatcga gtttatttcg ttttgcaggc ctctggcgtg 6660 tctggtcgcc atgtgctgag tacaacgcag tcgtccgcta cgcgggacga ctgcgttgta 6720 ctcagcaggc ctgtgacgcg gcgccgacta ggcaggtaag cagtggacat cgagccgcac 6780 ggtttccatg gctgcatccg atactcatcg agcccaggca aggcgatgtt ggtcagcacc 6840 ggcgacaaga tattgccctg agacgttccg gtgtgagtgt tctggtgctc accagactcg 6900 gtgagcacac cggccttaga aaacgccttc accaggacca agtacgcgtt tatccttgac 6960 tggcaatagc atccgctcca acagagcaga atgtgagata gagtcacagc gcacctcaat 7020 gtctgcatac agcacccacc gatagcttgt agtgctgtat tggtgaattt cggcgatcgt 7080 gtccctgaga tcgccgcttg ggggcggaat ccaggggaga tcggctcgaa agcggcctcg 7140 acgacaggct ccaacaccag cttcaacgca gcctgaacga ctcgatccgc agattgtcca 7200 acaacccgct acctcgacga tttcctcaac atgggctccg gtccgggcgt ccacaccagc 7260 agtattcgcc ccatagttgc ccgtgaccca gtcaaacgcc accaacaatg ttcgccgggt 7320 cacacacgag attgaacagg tcatcaaacc tgcggccacg atcgaccgac gatgacccca 7380 acccgataaa tcgtgttggc cacacaacac ccaagcagga cctaggacga ttcctcccct 7440 tcccgacgcc acccaaggcc aaggtgcccc cgcttcaccg ttcctgctgc gacaggcccg 7500 gcggcgaaga tctctcacct tcactgccat gccaatcatc agcacttcgt gacgcacgtg 7560 gatccaggtc gagcccgacc acatcacgcc gtttggtctc ccacgtcggg gtcggtaacg 7620 aacttgaagg tcttcacgcg atgcgactgg atgcccccac ttatgccaga tccgcgcggc 7680 caaggaaaac gaaatccccc acagccatca actgctccgg tgacgggccg ctccgacgct 7740 gaacggccga ttcgcataac atcgccgacc aacgtctcta cgagcaccat gacctcatcg 7800 atcaccgaag cacgtcccgt ccccggcgta cccgaaccgc gatatcagta tctagccact 7860 ccatcggaca ccaaccacac aatccacgcc cgtgtcacct gccccaccag cacccacaac 7920 accctcgtca accaccccag ccgaccccgg tcgccatcgc gcaactccaa gacagcaacc 7980 acatacaccg cccacttacc tcaaccaacc acacctaaac gcctcaaaac cacccaccac 8040 tagagcgcct gaattgccta ccgcgtgcga gaaatggttt gaggtgaaga aagtaacgaa 8100 agatcgacgc gactgactat gcccgaacct gtcgggcgtg gcttgcatgt ttgcacaccc 8160 acgaatcacc ggcggaccgc gatttcctcg accatgagcg atccacgtac ggtgggctat 8220 cccgtctcaa caggtggagg gcaaccgcac tccatgccct gctaccagga tgacgcggat 8280 ccagttgagg aagccaagca ggtgcatgaa cgttagtaat cgatggaacc tgtgagcagc 8340 tgtaacatag tgattccgcc tctacgacgt gccagccgaa atcttcgaaa gataataatt 8400 cgttttcggg tgcgaacttg aacggcgcat tctgcaacat gccagccatc ttcttattca 8460 tcattttttg aggcctgggc cggctaaatc gagcacccac caggtgactt cggatcgtgt 8520 aatcacctca gataaaagga tgacgtcacg gtcatcgagg tacataacca gaccctcggt 8580 gatcatcacc aacactttcg tagcgccgcc cagtgcttcg ttgaagaacg cttcgcggga 8640 gtgcgagtcg gtcaggtcaa ccacattggc atcgcggttc ctgctcggca agcaagtggt 8700 tcttctccgt aagcaacttc ggtagatcgt cctccaacca tgttaagcca gcctaaagat 8760 tcaaaagata cggccgggta gccaaaccag cggacaggtt aagcactcag tcacagcagc 8820 cggcaatcac ttcgacaatg gcgtcgtcga tgatcttggt acatgcgacg agccaccaaa 8880 ccgctgagac tcatccgtgg cactcgggcg acgatggcac gtctctgttc gccggcaaga 8940 cgtgtggcga gcggatcact gaacaaccca tcctgacgtg ccgactcggt tgcccgatac 9000 aacgccgtcc agcgagttgt atcggaaacg tgggtagtgt gcccggtgta taatgtattt 9060 tgcgtcatag cattgctgcc tgcattatgc gcgcacgtac acaggctcgt cgatagtagc 9120 tttgatccgg tagcggctgg taacgaagga gaatccgggt atgaatctga gtctgtatcc 9180 aatcaaggaa cccacagatc gggatcctgc ccagcgaacc ggtccagccc gagaacgacg 9240 atctgtgcgc agcggatatc ggacagttac gaatcactaa attcaccaga atgataattc 9300 aaaaaatttg aagctcaaga ctccggacat acgtgccact aaaatagtga catgcatcct 9360 cagacggaat agagaagaat cactaagcta agcgcgatag atctgcccgg taaccttatg 9420 cagtaagggt attaagcagg ctgggtggaa tggctacgac attttaattt aataacgtct 9480 aatgactcct gaagctaaga agacgactaa acggttcgga ggtgcgtgtc cagtggcaca 9540 cccgtggtca tacaaatgat tcggtcccac cgctagagtg cctattacgg gtggaatggt 9600 gatcgtcggt tgcagtggaa gccttgaact gctacgttgc gacggtcaat tgcttgtgag 9660 gcaccatcaa gacgttcgcg ctgtcacgtt tcaatgctgt acgtcctggg caaccatcat 9720 cctttcctta tgcctggtat gaatcgtctc ggcatgatgt tgacgacagg gatcaggcat 9780 cctaggcagc atgcgatccc tgtctcagcg gcctgggctc acccatctcg acaggagacg 9840 tgggcaggtc aactccctcc gccagccgca cagtccgatc aaaccaggat ttaccttcgc 9900 ccaacccgtg gaagtagacc gttgcgcgag cccgcgcgca aattaagaac ccgacatatt 9960 ggaaaagacc ggagaacgtc gtgcggtcct gtgatgatag cctaaatatg ttcccctacg 10020 cggtaagtcc aaccttgtac tctgtgcagc gaaagaagac cccgagtaat acagcaacaa 10080 gattcaaagt cactggcggg gcggcgtcgg ccacatctag aaagcccaga tcaaacttga 10140 tacctgactg ccgatagttg gtccaccttc tggctgagca atcaggatca gggcgaagtc 10200 gacatacttg agcaacagca accggccctc cgccactatc gtccccgcaa aagcaaacgg 10260 caatgcgtga aagacccgca acataacagc ggacagctgc tggcatacgt ggcgatgtca 10320 tgttggatga ggtcggtgtc cgtttctgga aagaccatgt tgacggcgca caaccatact 10380 ttgatgtacc gacaagctct ctactaaatg gccgcttaac accccccggc tacaccgttt 10440 tcccggtgct gaatcttgcg gttgccggtt tcgggtggcg gcgatactgg accgggagcc 10500 tatcccacgg acatgctcta tacgtatcta acgtatttgt taaagacgca gcccacgaaa 10560 ccagctaacc acatacgtta tggttctgtc accttgaccc ggtgtttcta agcgctgacg 10620 tcagttgcat tgagattgtg gacatcaatt gttccgagct gcgcaacgat cgacgcatac 10680 caccacagtt agcactcttc tgcacgaacg ccgccaataa ggcagaatcg gctgtgacga 10740 gtcatggtca actaccgatt atggcaaacc gtcgctgggc tccgcatact agaagacaga 10800 gtggtcgcgc tacctcaact tgctcgtcac tcatgagatt ctcagcaagt gaatctagag 10860 cacattcaag gtttgagtgc tacacccttg tgagatggtc gatccgcgga caaggaggac 10920 gtgcgattag caagcttggt ttctggagtg ttgttatgct tggtatcaac tcgataatcg 10980 gagcgggtat cttcatgact cccggtgaag tgatcaagat tgctggaccg ttcgccccga 11040 tcgcatatac tcttgcagga attttcgcag ccgtactggc aatcgtcttt gcgacagcgg 11100 ccaagtatgt caagacgaac ggttcctcct atgcctacac tacagctgca tttgggcacc 11160 gaatcggtat ctatgtcggt gtcacccatg caattaccgc ctctatcgca tggggggttc 11220 tggcttcctc gtttgtctca acactgttga gagtggcttt ccccgaaaag atttgggccg 11280 ataacgacga acttatcagc gtgaagacac tcacgttcct cgtctttatc gcagttttat 11340 tagcaataaa catatttgga aacctcgtga tccggtgggc caacggaatc tcagcgctgg 11400 gaaagatttt cgcgctatca gtcttcatcg ccggaggatt gtggacaatc ataacacagc 11460 acgtgaacaa ctacgtgacg tcccgatcag cgtaccaacc cacaacgtac tcgttgctcg 11520 gtgtcaccga gatcggtaag agcaccgcag cgagtatgac actcgcaacg atcgtcgcgt 11580 tgtacgcatt cactggtttc gaatctatcg ctaacgccgc agaagagatg aacacaccgg 11640 accgcaccct tcccaaagcc ataccactga caatcctcac tgtcggcgtc atctatatac 11700 tcgccttagt cgtcgcaatg ctgctgggat cggacaaaat tgtcgctact aaccacaccg 11760 tgaaattggc cgcggccgtc ggaaacaata ctttccgcac catcatcgtt gttggagctt 11820 tagtatctat gtttggcatc aacgtagcgg catcgttcgg tgctccccgg ctctggaccg 11880 cgttgtcgga cggtagaatt ctgccaacaa ggctgtcgag caagaatcga ttcggcgttc 11940 ccatagttgc ctttggaatc acggcgtttc taacgctcgc cttcccactg tcgcttcgat 12000 tcgacagcct gaacctcacc ggtctggcag tgatcgctcg attcatccaa ttcataatcg 12060 taccgatcgc gctcttcgcg ttggcacgtt cccggacaac gaattctgta tatgtgaagc 12120 gaaatgtgtt tactgacaag gtgttgccga tcactgcagt tgtggtctcg gccgggctga 12180 tggtatcgtt tgactaccgg tccatttttc tcacgcgcgg aggccctaat tacttttcga 12240 tttctttgat tgcgattacg tttatcggca taccggcagt cgcctacctt cactattaca 12300 gaaccagtgg aattaagtga cccaacgtca gtcgagcatc gccgagtagg attttgccta 12360 taacttaatg actattaaaa tgtaatctac atagatatta aataatgtgt ggctcaattt 12420 ttgagctaat agtcgtgatt caggaaagtt aagcattgaa tatcttctgg cactggaaga 12480 gtatagcgag acggcattgt ccttgaccat ttcggccgcg ccccgagaca acagcaagat 12540 caccaccctc atcgctcgga ctaaactcac gaccctagga ggatttcgag cagctaacga 12600 cagcgatcaa catgttgttc gacgataaga taccttgaca agttgattgt caagacgtcc 12660 gtggatggag gacagctgcg cggtgagttc cagcggaccc tgacccgctg gtccttgtca 12720 gtcactgtga cggcagcctt tatggtgcgg tgattggtat cattgcgacg gtcgcggcca 12780 tttggtgtga cggttgccaa aggacctcag acacactgcg caggtgtata ttccgaatag 12840 actttcacgg caggacaccc cttcatcacc ggagcaactg aaagctttgg gcaggcgatc 12900 acgaaagact agcattactc gaagataaac tcgtcttcag cttgtgtaag gccgaggact 12960 tggatcaact cgcaggctcg ctctcggatg tggcccacga ggaggtagtt tgtgacttaa 13020 tctcggaagg cgcggtgttt gagttgctcg agcaggttgg tgatattgat gtgttggtcc 13080 ccaatgccgg ttttcctaag tcgggcctcc tggagggttc caagcacgac gagatcaacc 13140 gcacgtttcg tgtcaatctt gaagcatcgg ttcgcatgac acgtgatctg ttgctcggct 13200 gacaggggct cgatagtggg taccttgtgt tcattttgtt gatctcggtg gtaaccgtta 13260 tgctacgggc atccggatag gctgcgacga agttcaggct acggtgattc gctctcaatt 13320 tgcgagaata cttgtggggc ggcgtggtcg gcgtttcggt tatttctcct agcgcgattt 13380 cgaggtcggg atgttcgcgg atagcgtctc ctcgccccgc ccgagcatag gcatacccaa 13440 gcggagggcc aacactgtct tacgggcgat cgagcgcagc aagccggctc cccgatagac 13500 tctatatatc aacctgctcg ctatgctcgc gtccgagatt tccggtcgaa tcgctggctt 13560 cgttgttgct aaaggcgcca aggcgattct aaggcgctcg tgtctggcga tactgttctt 13620 gtgatcgaaa cgattgaagt aacagttttg ccttctaaac agattcaagt gatgcctgca 13680 tcgttcttga ggtataattg atttcggcat tatcatccat cgtctccacg acagagaaca 13740 gctcgtctcg ccgcaccact tacaaacggt ccgcggggtg gattggcacc cgttgccacg 13800 gctgaatcac gagtgcgtgt caattgctct ttcttcttcg ctgttgcgtc aatagagcga 13860 cgaaatacta tatacgcgac aaaaccctcg ttgcgccaga taggatgcgt gtcagcaacg 13920 ggtgaatcca catccgtctt gtagattccc caccccgcga catagcttgg tgcggtagat 13980 tgccgtccta actatgggtt cggctgtgct aagaacctgg ctaggttgtt tgtggttaca 14040 ctgatcggac tgtcggcaat cgttgccgcg gctaagaagc ggttcttcga ctaaaccatc 14100 ctcaatagat ggaacacatc ggttgggtcg cgctggagag atatatcgga ttttattggc 14160 aacaaatgag tgaactgcac tgcattgggg ggtcgagcgt cgcatcggct cagccgcgtt 14220 gattgccggc ggtcggcata cccgcaccga agtgttcact tccctgatgg tgctgttctc 14280 cactagcgtt gtcgtgcttg agtttccact ggccgatccc ataatcggca ttgttatcat 14340 cgtagccatc ctgaccgtgc tgagcaccgc agcacgtgac gtgtgctgtc ggttggtcga 14400 cgaaatgaac ccggccaatg gtcgacgccg ccgagtaagc gttggcggcc taacccgggg 14460 tgcaggcggt gcgcagcgtg cggatgcgtt gaatcggtca cctccggcac actgatgtga 14520 aaattcatat cgatctcacc ttacatttcg tcgacgcgaa cgggctcaga ttcgcctaat 14580 ttctaggaag gctcgggggc aacttgtgcg catgctgcat ggctttccgg aacggccgca 14640 ctcctgggac gattttcgtc cacggatcgc cgcgcaaggg tacccgcgcg gtcagcccgt 14700 ttgtgcgccg ggcaccatcc cacaaaaatc cctgatcgcg agacaaatca aaatatccta 14760 gcgcgatctg cttgccttga tcgaagcgtt cggcgcccgc gatgtcacca tcattggaca 14820 cgattggggc gcctcggccg gatacggcgc catgacgctc gatcgagatc gagtgaaaaa 14880 actctttgtt atcgacattc cgcacccagc agcgctcaaa ccctcgccaa tgaagtgtta 14940 gggagtgttc agcactttcg ttgacatacc agcggccggt agctccaaac ctattcgcga 15000 gctatgactt cgcggtgcta cctaccacct atcggatatg gtccaccaag gtggaacccg 15060 aatccaatca agtttgacgc cgtacgtgcc agtttctcaa aaccccggcg agcgtaaacg 15120 cggcgttcgg ctactatcaa aagctctccc ctatactcaa ccacatcgct gaaaagcgca 15180 gatcaccctg ccagtggtcg cgtttgcggg cttcggtggt ccgattgccg aaacacacgg 15240 accaccgggg cgccgctcag atggtcgaaa ataagtacgt catcgaggaa gtccttgggc 15300 atttagcatt ccgaggcgtt tgtcaagcgg attttggttc atctgtgagc tcagatcggc 15360 actgcaccgc ttcaccataa gccggaatcg ccctcgaatc gcaaccggac tttcgcacat 15420 tttgctcaac agcgaccagg ttcgtggcct atcagaatgg acggacatga gtctcacgtg 15480 acgatcacga ggcagggaag cttgacgacc catcatgttg ccatgccagc gtgcgatcca 15540 tctgctgtgt tcgatgtgtc gacctcacgt acactagggg ccgcggtggc gcgacccggc 15600 tcagagcgca gccaggatgt aagactacat gttccaatcg accacagaac gtggatccat 15660 tttcaggtgc ttcatcggtt gcggcgtttt ctgttagact tctagaatct ggtcgactgg 15720 agttgactcc atcgctcagc gaagctgaac ttcaagtcct cggtggtaaa cccgtcacgg 15780 tgcagggtgc gttgaggtga caacgcacgc acgttttacg tacgcttgca agtatgcaag 15840 agcagtacat aaatgaaatc cataggccat aatccggcct ctagaaaggt tagttcataa 15900 ctagccgaca tcgctgggca agacccggac cttggtgctt cggtgttatt cgctaatacc 15960 agcgggcagt gaagaagtgt cgatgcagga tgcactagcg cccatctaac gataccacat 16020 agatgttggc ttccaatagc tctgcgcaac aagaactctt gcaaaccgac atggtgttga 16080 taactatctc gcgcacgtat ttcgcaggtt gacgacaccg caacagatac tttgccgttc 16140 ggcgtggcga cccatgcggt ctcgaatgat tttgtcgaat agatcgggcg caagcacgga 16200 cgcgtatatg atgcgcgcga aagagttagg ttccggcacg cacgacaccg atgatgagcc 16260 aattggtcga caccccagtt gccgggagac aacaggaacg actgcccctg cagtcaccaa 16320 cgctgcaccg tcggcgcttg gcaccgacat tgccccactg agctcgatgg gccagagcac 16380 acaagcgagc gccagctcca catcatggct agtgtcgtcg tagtcgccca aggtcaggac 16440 gactacgacg acagcgaaga gcccgaggac gaagaagccg gttacggtca catgctgtat 16500 cagccttctg cacaggaaga ctcgctagaa tttggtgggg atgatcagcg tcctcaacct 16560 tgcccggtaa gtttcatcgt ctgggcggtg ccgtgctcct actcgacagc ggtggcgggg 16620 ttccggcgta ttcatacgtc tccgctcaaa gcaacatcat aggcaactgt tgcaccggta 16680 accattggcg gcaagcaccc gtcaagaagt agcaaccgat gtgctcatcc ctggacccga 16740 agcgtctctt acgcttgctc tgctactcga atggcaaagg agatgccgtg accaatcccg 16800 cactggccac aaatgttgcg caacatgatg gtcccggacc gcatgactgg gtagccagga 16860 gctctgtgcc ttcttgctca agcactcaga gaatgcgcca atgagcacag acgaacttca 16920 gcaattgaaa gggttgatcc tcatttcgcg cctagagatg gttaacaccc ttggtgtagt 16980 agcggaaaag cagaaggtgg tttagctccg gacgagaatc cgtcccgatt tacagcccgt 17040 aataaacctg ccaaccacga gtttcctagc ctatcgctca ctcgctgtgg gtgaacaagc 17100 cgaggagtaa tccagaaaac acttcactat tcgagactat cgatggttta acgacagctg 17160 tgtcaagctc gcaaaactgc gctatgtgcg gcgcgtggcc agcgccgctt tatattgccg 17220 tcggcgtcaa taaccacgac agctcgtgcc agaaaaccga acatcgggct atcggcgatg 17280 gtgacagcat ggagtgccca ctgtatactg cagaaagccg atcatcgata ggactctggc 17340 tggtagagtg ataaccactt gataacgtgg atattccgag tcagtaggtt gatcgacagg 17400 atcatctgca ccagatcggc acagaccgtt cgatgggtaa tatccactcg taccgaggat 17460 cgggtagagc ccgagatgta tttgcaagtg ggaaatatcg ttgctgtcta gcttgacagg 17520 gatgaagcgt tcccccgtaa agtctgacat ctgattgatt acggtgattt acggcctccg 17580 taggtgtggg aggctcatca gaaaaatctt caaccgcgtc ttttggctgc tgcggtcgta 17640 agtacagcgg cgagctcgcg atcgcgcagc acggcatcga actgttcagc gtggcgcaga 17700 cagctctggc gtgaacaacg gcaccactat ggtgcccgcc ttgaccgcta cgtagaaccc 17760 ggcaacgtag tcgatgcttt gcggcgcaca ggatgataac ccgatcgtcg tgacctgtga 17820 attgttggat atgtacaccg atggtttgca gtcgggcacc gcattaggcc caagttaatt 17880 caatggcctg tccgatcagc gcggacgtaa tccaggtacc cgatacgctg tcgcgtcacc 17940 tacatctgcc acgttcagcg ttcgatgaga gagatcagcg tggtgtcagg cgaccaacac 18000 aacactacca tcggcatcca aacagtcctc gatcactaac aggccttttg gagccacgga 18060 gtcctgcccg gtaaccgtaa tctatagacg caactataaa acccgccaat gagacgctaa 18120 ctgttacgcg acagacttga aacttgtttc gtgtattcga gtttcgagat ccagccgaac 18180 agagccagtg ccaaacccac cacaaaatcg gcttcagatg gacgccaagc aggagcatct 18240 gtggacccta acgaccacaa catctcaacc acgaccaccg aaagcgcgca ggcttgggta 18300 ctcacctacc gcgagctgta tcggtccaag ctagtgcaag caatcctcac cgttcttggt 18360 gacgtgctgc tcgttgcctc aattccgatg atcgtactgc ttcccgaatt aggcatatac 18420 cggtgctgtt ggtggcgctt cgctttccta cactctaagc tgattcagtc acgcgcctat 18480 gcgtggacgg attggtgctt catccagctg cagtaactgg ctccaccggc aatcacaacg 18540 tgtccgcgtg gcaatcctga tcgggttgct cattgcagcc gcacttgtgt ggttgatcgt 18600 ctaccagttt gtccaatgtc gtaggttggt tgatctccct aagacaagat gtcacccatc 18660 cagagactcc atcatagcgc aagaaagacg gcagggtagt caacctgacg aggagacagg 18720 cccgacagta cacacgacac gacctaatgt cgcacctcac caggctatgt gtccgctacg 18780 tcaaacgctt tatgccagat ccgtacttat tcgctgccat ccttaccatc attgtggtga 18840 tgcttaccgc gccgctcgtc agagacacga cggccgccag catgttcaaa gcgcggtaca 18900 gcggagtatg gggatcgcag catatcttcc accttcacgt tacagatggt gcgggtccta 18960 gtgactgggc tacacgctgg cctaggctac ctgttctgag tagcgccatc gtccatatcg 19020 gagtaaactt aagaattagg tgcaaggcac tctaacctgc gtttcgccct caacgccgcc 19080 cttttcttgc tgaaccgagg acttggtctc gtatcgggta ctctagtcgc ccaccaggtc 19140 gcgaagcgac tagtgggcgc catttcagct atctcatcac agcggcattt atgggcagca 19200 gtggtcttcg tatgcgctct ggctccgtac atcgacattt aatggtgaac cgttcgcggc 19260 acgggaagat gcagtggacg acgtagccaa catgtgaata ttattcacac ggctgaagag 19320 agacggctac accatactgt gaatagatta catctagggt tcaactacct tactgcagtg 19380 gtgttttaag tagaattcta gctatgttcc gacgattcgt cccgacattg tgatgccagc 19440 attgcaaccg tggcagcgtg attcgcctgg tgagtatgca cgtggcataa ccccgccagg 19500 ttcacacacg atttccgaag taagttaccc agcaacacca ttcagctttc tcaccaggga 19560 gaaagacatg tcgaatcgga aattctcatt cgaggtgacc cgtactagta gcgcttctgc 19620 cgcagtctta ttccgacttg tgacggatgg cgccaactgg gcgaagtggg ccaagccgat 19680 agtccttcaa tcaagttggg cacgccttgg tgatctgaga ccaggcggca tcggagcagt 19740 ccgcaagata gggatatggc ccatactggt acgcgaggag accgtcgaat acgagcagga 19800 tcgtcggcac ctctacaagc tgatcggacc tccgaaccca gccaaggact acctcggcga 19860 ggtactttta gcgccgaatg cagcaggtgg taccaacatc cactggagtg gttcgtttac 19920 cgagaacatt cctggaacag ggccggtgat gcgggcagcg ctaaagggtg cggttcggtg 19980 tttaacggtc cggttggtaa agacggctga acgcgagtcg gacggtgttc agtaacttta 20040 ataccttcag gatcaaggtt tttcgtttcg ctagtcttgg taaccaagat aaaaggtcgt 20100 cacattcgtt tggctcagtc gccgatcaag ctcgttggga tctgagggaa ttgcgccagc 20160 agtggtgcaa catttgagca gttacgtgca gccaacctag tactggtatt tcttggtcat 20220 gtgctcgatg acctgtagct acgattgcgc tcagttatcc cgtgcctggt tggctcgcat 20280 agcggcatca cgtgccggtt gagcctggcc ctgaaagtgc gacatcattt cagtggcgaa 20340 caactcgaca gaccatttgt atgctgtcga tgggctgcgt gtgggccatc gacagcatac 20400 aaccgaatcc gccagactgt atcctacagc cgctgtaccg acacaagtac ccgccccagg 20460 gtacatgaca acggttaccc gattaattca ttattgatga tgtcgatcac ttcgtcgagc 20520 taatcacccg acatagtcat ctgcgggcat gcagttacta ttctgtaagt gccgaaacca 20580 cgcctcgaag ccgaatttca cgtaggctcg agcctactca tccgtctcgg cgatatgaaa 20640 aagactgact agaggaccag ttcgtgctgt cgattttcgt cccaaaagct gcggcgcact 20700 cttcgacgac gccccagtgg taggcgagca cgtagaaact ttcaattatc aatgttgttc 20760 tgatggacaa cagaccgata ccgtgcttgc ccgccacccg cataccggtc agtgaggcga 20820 ctacagcaac cggccactgg aatcccgccg ctggagtacg cagcgaactg cagctgagca 20880 tcgaataact gattgtgtgg cggtcttggc agtaacagtt tccccggcca ggagaccaca 20940 cgagaatgtc ccttggttgg tttcgaaaaa ttcatgctta tcaatggaag ttaacccgat 21000 ccagcagtat caaccggtcg actacccaga actggttacg gtacacgaac gagatgaccc 21060 cagtacccag gccggaccag cttggcccgt tgctcagcgg cagcgatgaa gcctcgggta 21120 cactaatgat ctcgctaccg gccgtgtgat gctcacccgt aatacttcgt cgaagccgat 21180 agacgcaaga cgctctatga actccaagtc acattggagc gcgaaagtgg gatttgtgcc 21240 cgcgcggtgg aatgaggcga tgaaatattc aaactcgagc ttggccactg cggtcccccg 21300 cactctaagt gacaaaacat aaccccaaca caacggccag accaatgcaa cggctagact 21360 ttagagtccg acagccgacc tcatggtgtg ctcagccacg agcaaacagt tgccgagtgg 21420 gtatgcctaa cgatatcgac acatcgcacc cttatgtacc agccgtcaca cacgttggca 21480 atgcgaccga ccgccaccga cgccaagggt ggtgcccagc ctccgccatt ggggccacca 21540 gcttctgacg ttgtggatgg tgtcggcaca gctctagaag acaaaacgtc gccgtagttg 21600 ttggcgctgt ggtgctgctt gacgccttat taccgtcacc accgcatcca gaaccccgct 21660 accaaccgag cgtgactaca ctggaaagaa gtacgaacgc catcataggc tgatgtgccc 21720 accaaaccca tttccgttcc gcctgctttt cccaccccca taatgaacgt gagcaaacgg 21780 attgtgggct actacagaag acaagcaact ggtataggca tttttcaaat cgaggcgacc 21840 tagtatcact cacctagcac cgctatcgca agttccaata ctccaatata atattcaata 21900 tttctccgat attccgcttg gccttccccg accggcggtc agcggtgtcc tttacccctc 21960 cttggtgatc aaccgccgca gcgcgacgcg atcgggggta agcagctcaa caagccgcgg 22020 gtggttcacc tcagcgacga tgatctcgcc cacctcctga taaacctcgc tgaagatgcc 22080 gtgagatttc atcttggaag tctgatagag attatcctcg gttggagtga cgtaaatcac 22140 cgtgtcagcc ttgaagcggt gcaccagcca gaaatggatc aaggtcatca gtcgcttctg 22200 gcgaagcttt tcggcgaagg tgttctggtc gcgcacttga aggatgctgc ggccgcggcg 22260 atccttgatc ggatcaacga tgacgttggc cagctgctcg tcaccgttgc cgtagatccc 22320 gagttcgagc acatccgagc cggcgcggcg tggccgcagt tgcacgcgga gtttctcgcc 22380 aagctggtag tgctcactcc acaatgccag ccattcctct agcagcttct tcggcacctc 22440 ggtctgcaca agatgctggt gctgggtcga acctttgccc atggccttgg ttgtcgccgt 22500 acgtccggag gacgcagcca gcgctgcatc gctacgcggg ccgccgacca gggtctgcgg 22560 tgtgcggtag ggcgattcga ccaggcgcat cttgcgttgc aaccgagcca acgccagcat 22620 gccgtcctgc cgcagcgcgg tggcgaactc ctcggcagcg acgccgtcga tctgatgtcc 22680 gccataggta atgaagttga agacgaagcc cattttccca agctcttcgg gaaagcgctt 22740 catctcctca tcactcatac cggtggtatc ccagttgaac gacggcgaga gattgtaagc 22800 cagcatttgc tctgggaact cggcgtggat cgcctcggcg aactgccggg cgtcggccaa 22860 atcagcggtc ttggtctcca tccaaaggat gtcggcgaac ggcgctgccg ctaacgactt 22920 ggctatcgca tactgaatac cgccgcggat ttggtagtag ccttctggag tcttcgccag 22980 ctcgcaatcc caaccggggt cgacacccaa ttccttggcc ttttcgcgtg cagcgtacag 23040 agacgcccgc ccaacaaatc gccgccactc ctcggggctc atgccgatca gctcgccttc 23100 gctctcgccg aattggagca tttcttccac ggcttcgccg taggtcatca gcccggcgtc 23160 cttctcccaa gcggccaata accgatattc aacttgttcg aagagatcgt cgatcgattg 23220 ctttccgttt tcctgccaag cattgacggt accggagacc tgggccagaa tcccttggcg 23280 atcaagccac gcgctcgcag cagcatattc gccatcgcct aacgcgtaga ggagatggcc 23340 atggagttcc ttaactccca gctcgtagaa acaccgcacc aacgccagga aacaagcctt 23400 gtaagaagga atcttcagat tggtggcgcc cagcaagaac ggctggtctc gctcatcggc 23460 gcgactgtcg atcaagttgg ccgcctcggc atctgtacgc gcgacgatga tgccgggcac 23520 ccgcataatg tcgagctgga agcgggcggc gttgaggcgc ttgatttgtt cgtccgaagg 23580 cactagaacc ttcccgccct gatggccaca cttcttggta cccgggcgct ggtcctcgat 23640 gtggtatcct ggaacgccga tctcaacaaa tcggcggatc aggttgcgta cgtgcgagtc 23700 accgccatgt cccgtgtcgg cgtcggcgat gatgaatggg cggtagtcat acgccggagt 23760 ggcggcacgc tgctgttcag tcatgtgtaa ccgcaggtac tgctgattgc ggtcagcagc 23820 cagcagggcg cgcaccagta ccgcggcatc atctggcacc tggctcaggg ggtagctggc 23880 gagatcagga ccgggatctt cggtgatgga acccttagct gaggttgccc agccgcctag 23940 atagatcgcc tcgatgccca tccgcttaag gctgactgct tgccctggcg aataggggcc 24000 gaacgtcgta acgctcttgc cggccgcgaa tagctcgcgc aagcgagcgt agaaagctgt 24060 cgcggcgtct cgtgccacgg tgtaatcggt ggggatggtg ccgcgttgtt ctacgacctg 24120 gcgggctgta taaaggcgaa taatcccggc aaaccgtggg tcgtcaaagt attgctgcgt 24180 tgcggcgact tcctgcgtaa acagtgtgtg gacctcggtg ttcgtgtcca tgatggccat 24240 gggattgcgc tcctccttag cccggtcccc taacggagag tagtgtagtc tatcgtccag 24300 gttagttgag ttacatcgct ggacgaccgt ggccggtatg cctgccaatc gacatcgggg 24360 gcattcccgc ggactactcc atcacgttgg ttgccagagt gataggaagg cgggttgcta 24420 gacaacgaca cccggactgt tgatgcacca acggttccca atttccagtg cttaaagttt 24480 atagactcga caagcgctaa gacgcactgt ctgagaactg gtattttgaa cggcaacaac 24540 ggatttccag tgggtgtcag tgcgcatgcg gccagctgca ccctgctttt ctcgccaggc 24600 aatgttgctg gccggtagtc ggtgcggtgc gccatatcca ccttcgaggt tggtcggctg 24660 caacactggt ctggaagtct cctctagcac gggtttcggc aaccataaac acatgggctt 24720 cctctgtcca ggccgaacca gaacatcatg tggatggcgc ctgccatcgg ccgtgacatg 24780 aatgaaaaaa tttccaaggc gcagggcgcg cgctacgctg actcggagta gacttcgtag 24840 ttgatcgccg gcagtagatt atcgcgaacg cgtgccaccc aggaacgacc acccggcagt 24900 gaatggcgcc gacggggcac ccacagaccg cgaccggctt cggtataggt acagacccag 24960 cacctgcgtg agaaccagcg cttcgcgaca ctcccacccc agcccatcaa gcagaatgcg 25020 gatttccgca gtgttctcga cctgaccccc gtgacagccc agcccaagcg ggtcgtcgag 25080 atcggccacg tgcgcggttc gtgatctgct tgcgttgtag cagatctgat caacgactgc 25140 gcggcgggca atcgacaaca gctgtccgag ccgtcgaccg tcctgcgaaa caggagcagg 25200 aaacagaatg cctacagaaa cgtttcctgg gttaggtcat cggcgctgtc gtaatcggta 25260 aaaattggtc accatacgcc acacatcgcg ctgtgtggca gggatcagct atgacaatgt 25320 ggcccgatag ccctgtccgg cagggtttgg cgaaccgagt aatattgtcg tcatctatcg 25380 acatgcatag cgcgtaagcc acgcgtcccg gaaacttgtg gataggtcgt gacgacctta 25440 tttctgggta gagtcttcca ggaaaatagt gtgcaggagg tgaaaagcta tgatgtcggt 25500 gacgaccacc gcaattgggg gagaaccctt tgcctgtgca gcggatacag ctgaacatca 25560 ccgggatgtc ctgtagttgc gtgcgccaaa cgggtggaat aacttgccca acaagctgtc 25620 ggacttttcg acgttagtta attccgccac ccgagtggcg gcgattaacc tcagcgaggt 25680 cacccagacc gctgaggtat gtgaggcggt ccgtcgagca gcactgtgca cagatggcgg 25740 tgaggccttg caacgcaggc aagccgacgc cgataacgca cgatatctac tgattcggtt 25800 agcggtcgct gccgcactct tcgtgcccct agcccacctg tcggtgatgt tcgctgtgct 25860 gcccagcacc cacttccccg gctgggaatg gatgctgacc gcgctggcca ttccggtcgt 25920 gacttgggcg gcgtggccat ttcatcgagt agcgatacac aacgcacgct atcacggtgc 25980 ttccatggag acactcatct cgaccgggat caccgccgcc acgatatggt cgctctacac 26040 cgtgttcggc catcaccagt ccacagagca ccgcggcgtt tggcgggcac tgctgggcag 26100 cgacgccatc tacttcgaag tcgccgcagg catcacggta ttcgtgctgg caggtaagta 26160 ttatacggct cgtgccaagt cacacgcgag cattgcgctg ctggccctgg cagcgctgag 26220 cgccaaggac gccgctgttc tgcagcctga cggttcagaa atggtcattc cggccaacga 26280 actcaatgag cagcagcgtt tcgtggtgcg ccccgggcaa acgatcgccg cagacgggct 26340 agtcatcgac gggtcggcca ccgtcagcat gagcccgatc accggagaag ccaagccagt 26400 ccgggtgaac ccaggcgcac aagtcatcgg tggcaccgtg gtgcttaatg ggaggctgat 26460 tgtggaggcc gccgcagtag gtgacgagac acagctcgcc ggcatggtcc gtctggtcga 26520 gcaggcacaa caacagaatg ccaacgccca gcggctggct gaccgcatcg cttcagtttt 26580 tgtaccctgc gtgttcgctg tcgcggcctt gaccgctgtt ggatggctga tcgccgggag 26640 cggacccgac cgagtgttct cggccgcaat tgccgttctc gtcatcgctt gcccgtgcgc 26700 actgggactg gcgaccccta ccgccatgat ggtggcctcc ggccgcggcg cccaactggg 26760 aatattactc aagggccatg agtcgttcga ggccacccgc gctgtggaca ctgtcgtgtt 26820 cgacaagacc ggtacgctga caacgggcca attgaaggtc agcgctgtga cagctgcacc 26880 gggctggcag gctaacgaag tcctccaaat ggcggcgaca gttgaatcgg cgtccgagca 26940 cgccgtcgcg ctcgcgatcg ccgcgtcaac gactcatcga gaaccagtcg ccaacttccg 27000 tgcagtaccc ggccacggag tcagcggcac cgtggccgag cgggcagtgc gggttggcaa 27060 accatcatgg atcgcttcgc ggtgcaactc gaccacgcta gtcacggccc gacgtaacgc 27120 cgaattgcgc ggcgaaacag cggtttttgt cgaaatcgac ggtgaacaat gcggtgtcat 27180 cgcggtcgcc gacgccgtga aagcttcggc ggcagacgct gtcgccgcac tccacgatcg 27240 tggttttcgg accgcgttgt tgaccggcga caatccagca tcagcggccg ctgtggcttc 27300 ccgtataggt atcgacgagg tgatcgccga catcctaccc gaagacaagg tcgacgttat 27360 tgagcagctg cgcgaccgcg ggcacgtggt tgccatggtc ggtgacggca tcaacgacgg 27420 gcctgcactc gcacgcgccg atctcggtat ggccatcggc cgtgggaccg acgtcgcgat 27480 tggtgccgcc gacatcatct tggtccgcga caatctcgac gtcgtaccca taacactcga 27540 cctggccgct gcaacgatgc gcactatcaa attcaacatg gtatgggcat tcggctacaa 27600 catagccgcc ataccaattg ccgccgctgg attgctcaac ccactagtag ccggtgcggc 27660 catggcgttc tcatcgtttt ttgtcgtctc aaacagcctg cgattgcgga acttcggggc 27720 catactgagc tgcggcacta gtcggcatcg gacagtcaaa cgatggcgtt gtccaccgcc 27780 cactcggctc cgttcaactg cgtgtagtcc tgtggacgct tccccattgc gacccgtcgc 27840 acacaggacg ggggttaaac cgccgaccca tcggtaggcc atagatgacc gcgtcgtcgc 27900 ccacgagagg cgttccgggg caacacaata tcgagatcga cgtcgacttc atcatcgaat 27960 gtcggccgtg gagtcgaact gtgtcgccac actgcgatag caaggaccgc accgatcgcc 28020 accggcagat gcatcagaat tcgcagcgtg atggtggcac cggcgactac atctacgacg 28080 acgtagactg tcaacaaacc gacgaacacc gtcaaaacgc ccgcaagccc ggcagcgaca 28140 cccggccaca gaaccgctgc catcatgatc acaccgagcg aagccgacca cgccgttgac 28200 tcgtggagca ggtaactccc gaaactcatc gcgcgatcgt gtgtcagtcc gacgcttacg 28260 ccgagcccct gcacagttgc caggacgatt tgtgcgatgc ccacgcaaag caacgcccag 28320 cgctgccacg tcattaatgg acgtcgccgc cgcggcggcg ccacgatccc gagagcatca 28380 acaggtgtga tagcaggccg ggagtcgacc agctgacgca ggtcgcgtgc ttggtcagct 28440 acctgatcaa accacgcacg acacgcactg cactcaccaa ggtgctcatc gacacgcacc 28500 gatggcacgg cctctctctc gccatcaagt cgggccgaca atgcttctcg ggccacctcg 28560 caatccatac ccctatcgtc gcgcatacgc caacggaatg tcctgtcggt gctcatgtcg 28620 acgcgcaaga tgctaatgag acggcaggag cgttccgccg aatttcattc ggcctaatcc 28680 ccgaatcgtc ggttgaagtg actgctcacc ccggactgat gctcaccacc gcatccactg 28740 cgattgcacc gaccatacca gcgtaatcac atccataggc caaaaccacc atcgtgccgg 28800 tagcaccaga tccaattcca cctggggtcg tgctgtgcta gttaggtcat tatgttgcga 28860 cagttgaata ggcaacgtcg acaactatat ttttagcttt attccaatgg tcgacaaatt 28920 tacgtaattt gtggatttcg tcgagtagat ctctggctgc ggattgctgt gcagcaaatc 28980 gtcggatggg ctgttgctgg tggttttcgc tgaccatacc aacgcgagcc taaccatttg 29040 ttgaagcagc agattgccgt cagctgcgcg gatagcagct tcgttttgat ggccagcgta 29100 gcggaacaga atcaggatgc agtcgcgaat cgctacgacg gtccggtgca agtaaacgtc 29160 gggagcgatt gctcgccaga ttgccatact cccagataaa cgatctccga acaagcagtc 29220 gccaaatcgc gccacagcgg cagcaatctg cggcgctgga gggagaatct gtcgagaagc 29280 agttcctcaa gtagccgtgt gtatgcggaa acaactatgg actctcccac ccctgtgggg 29340 ggtagaacag caagctccat gcgttgacga atccgacagt gtcaacatta aaattaatag 29400 tgttgtgtcg tccggttgct actacattgg tagcaatgga aaccgctgcg gcctgtgcga 29460 gaaatccgac agcgataact gtcatgctga cagttatcgc tgtcggattt ctgtatattt 29520 ctcgaatgca tagaatgaaa agcattacgg aaaacaaata tcagaggagc gagttgtagg 29580 agatcgccgc cttcacagtg gcttccgatg aactggaaca tgaattctgg cctagcctag 29640 ctggatggct ggatacgcca cattacgatc acgcatccca ctgcaaaatt agatcgacga 29700 ttgtgctcac agtcacggta gaataagtta acaagctcac cttagttaga taacgagaca 29760 tcggatcgct tgagccaaat gtacgccacg agaaaaagga tgtcgcggtc gaacattgct 29820 gcgagttcgc cgcgtgcata tagcagctta ggtctatagc cgtgacagcg accaattgat 29880 gattgccgtc tatactgctc ggttttgaag agcacagctt gccaccacaa actcagcaag 29940 ctattgagcc gtttgtcctt cacaatcaaa ttcagtagcg caaatcgcag aatcaaagaa 30000 atgagcaaaa aataaaagaa atacgctcaa caacaaagcg gcaatcgctg aattcgtgcc 30060 acctgtaatt gtggctcggc atgcgattta acgtgtgaag tagtgtagca cggtcgatag 30120 cagatagcaa cccctagggt cgacgctgca tcaccagaat caagaccagt agggtgttca 30180 agcaacgggt gcccgaggcc gcgcaaaatg agcaaagtga tttgttgaac atggcaatcc 30240 aaagtggagt tagttgcgtc cgcgaggcga cggtctccaa cgagttctgc cgactccagt 30300 tgctagacgc acaggtgcag ccgcaccctg gccggtgttt tcatcgatct actttaagac 30360 tttaggccgg gaatgcgctg gcgcctcagg ctgcccccgc ccagctgcgg cgactgagcg 30420 ttatcaatat cagccgcagc cataggtcga tggcgagtgt cagcgcgccc ccgcagacaa 30480 tcgagtgctg ggcatcacat acgttattcc taggcagggg gaactttttg cgcgctttcg 30540 ccgaccaaca ccgggaagtg acggcaaagc catgctttga gtgcatacag tcgagcgctc 30600 tacacccatg aaaggaggtg aagctctgac aggcccgatg tggatggcca tacctccgga 30660 ggtgcactcg gttctgttaa gtgctggaca gggggctgaa tcattgcttg ttgccgctac 30720 tcagtggcag gagcttagca aacaatacac ttacgcagct gccgagctga ctcggctgct 30780 gactcatgtt caggccacca gctggcgggg aaccagcgcc acacggtttg tggcggcgca 30840 tggtgcctat ctggtctggc tcgaacaaac ttcaatcaac aacgcaatca ccgctaaaca 30900 gcatgaaatc gcggcaatcg cttacagcag cgcgctagcc gccatgccca cgttggcaga 30960 acttaccgct aaccgcgcaa ctcgtggttt cttgattgcc accaacttct tcggcatcaa 31020 taccattccc attgccctca acgaagccga ctacgttcgg atgtgggtgc aagccgccga 31080 cactatggcg acctaccagg ccatcagcga ggcggtgacg gcaacaatac tacctaccca 31140 agtagcgcca cctatccttg cgccgggcag cgcaacccaa aacgtcctgc agtccgtacc 31200 ggattggatt gttcaactac tgacggacat cttggatttt atcgcagatc catacaaata 31260 ttttctaaga tttttccaac gattgggatt cagacccgct attgctgttg tccttgccat 31320 tattgctttg caattgtacg actttctttg gtatccctat tatgcctcgt acggaatgct 31380 cttgcttccc tttttcgcgc cggcattgag cgtcctgggt acactgtccg tgttgtggaa 31440 cggacagctt tcagccggac tgcctcccaa tcccgcagga tctcacccag acaataacgc 31500 tggcccacgc atccacgttg gagtcgcgcc acctgcctcg gctacttcca gtggaaactc 31560 atacacgagc aactccgcac ccagcacatc cgcatcggct acgactgaca accccctatc 31620 ttcacccagc atcagatacg ccatacccgg cttgtcgcca ccagaggtca gctctggccc 31680 caaagccggc acaaagtcac ctgacactgc caccaacacg atcgggatca ctgccgcggc 31740 aagaacaaac tcgccttccg cccgggcgca ccgtaaacga ggaaacaaga ccagaggtgg 31800 cgcacgcggt taccgttacg aattcgttga aggaaccgcc accatggccg atactgtcga 31860 cgcccccgac cactccgaac ccacgtcgca cacaataagt aaccacagcg ccggccccat 31920 cggctttgcc ggcaccgtgc cgacaaccgc cagcactccc accggaatgg ctgccagtac 31980 aagcagtagc gtcccactgc tccccactac ctggataact ggcaccagcg aaacggcagt 32040 acacgaatag agaaactttc actagcttgt ccgactgctt actcttcgca tgagcaaaat 32100 gcaaccgatt tttcatcaag gaggtatgga tcgtgacggc gagagatgct caaagatgtg 32160 gaccaaaaac agtaagtaaa tgaggagaaa aagaatcaat gacgctcgat gtgaaaggtg 32220 atggacttgg tgcacaggtc acaggggttg accccaaaaa cttagacagt atatccaccg 32280 ccgaaatccg caaaatagtt tatgtcaata agcttgttgt tttaaaagac gtccacccaa 32340 ctccagaaga atttataaaa cttggcagga taatcggaga aatcgttcct tattacgaac 32400 ctatttatcg ccataaagat tatcctgaaa tatttgtttc ttctaccgag gaagggcagg 32460 gtgttccgaa caccggcgcc ttctggcatg tcgactatat attcatgccg gaaccttttg 32520 cattttctat gactctgcct cttgcgatgc ccggacacga ccgcgggact cattttatcg 32580 acctcagcca ggtttgggaa tcgcttccca acgctatgaa agactcggtg cggggaacgt 32640 atagtaatca ttctcctcgg cgctatatca aaatacgccc aagcgatgtt taccgacctg 32700 taggagaagt cctagccgag atcgaagagg tcactccccc gcagaagtgg cctacagtga 32760 tcaagcaccc gaagaccggg caggaaatcc tttacatttg cgaagcagcc accgtttcgg 32820 tcgaggacaa aaacggaaat ctacttgacc cgatggtgct gcaagagctc ctaaccgcgt 32880 cgggccagct tgaccccgac tgcaaatcgc tgcttataca tactcaacac tacgaggttg 32940 gtgacgtcgt cttgtgggat aaccgggctc ttgtgcaccg ggcgaaacac ggcacggtct 33000 cgggcacctt aatcacgtac cgtctgacct tgctggatgg cctcaagaca ccgggatatg 33060 ccgtatgagc gccgagttgg ccccttctct gcagaacgcg gcggaatcca caaacacctt 33120 tcctatggca gaagatttgc ttggcagcat actggaaccc tactcttaca agggatgccg 33180 ctacctcatt gacgcacagt acagagccag ccctgattcg gtcttcgctt atggcaattt 33240 cgggattgaa gagtccgctt acattcgagg tacaggccac ttcaatgcgg tggagctgat 33300 gctgtgtttc aatcagttag gttacagcgc gtacgctcaa agtgtcgtca acaaggatat 33360 ttccgcactt cgaggttggt caatcgcaga ttattgcagg aaccagcttt ccggcatatt 33420 gattaaaaac acatcatcgc gatttaaaaa gctgatcaac cctcaaaaat tttctgcacg 33480 tttgcatgta tatgatctcc gcatcgtcga acgaacatgg cgctatctcc agttatcgaa 33540 caccatcgaa ttttgggacg ataacggagg gtctgcgata ggggaattcg aggtcgcgat 33600 acttaacatc ccgtaattta cttgtaggag attcgcttta cagctatgtc gcacttaccg 33660 cctacagtcc tggaacggat actgaagcag gcacacgagc gtccggaggc aatcgccttg 33720 cgtcgcagcg acgggacaag cgagctgcgg tacggtcagc ttgttgccga agtcaatggg 33780 cttgccgcgc atcttagtgc tcagtcggtt tctcaaagat cccgggttct cgtcatttcg 33840 gacaacggtc ccgagacata cctgtcggtg ctggcttgcg cgaagctcgg agcgatcgca 33900 gtcatggtgg acggcaatct tccgcccgca accatcagtc gtttcagcga aatctgtgac 33960 cccagtgcgg tccttgtcgc gcgagagtgc agaatagact cttcctcgct gccggaaata 34020 ctacactcaa taccggccat aacggtcaat accaccgctg atgcaacgta ttccgcttgc 34080 tcgttggata tagattattt agccggtaac ctaaactacg gcaccgatga cccgttggcg 34140 atgaccttca ccagcggtac aaccggcgag ccaaaggccg tgctgctacc caatcgcacc 34200 ttctttgcta ttccagacat tttacgggaa aaaggtctgg cctggatcga ttgggtcgtc 34260 aacgaaacca cctactcacc tctgtcggcg acgcatatcg gcggcctctg gtggatactc 34320 aactgtttaa tgcatggagg gttatgtatc accggcggtg agcacacgtc gtcgttaacg 34380 gaggttctta acgcgaataa agtcgcaaca acatgcctag ttccaaccct tctttcgaaa 34440 ctggtttacg aactgaagtt cggcgatgtg gtgactccgc cgttgcgact aattgtttac 34500 ggtggttcgc gggtaattgc agctgatgtg cgatttattg aagctgcggg tgtgcgcacc 34560 gcacagttct acggtttgag cgaaacgggc tgcaccgcct tgtgtttacc aaccgataat 34620 ggatcaatct ccaaaatcga ggctggcgct gttggacgtc cataccctgg tgtggaagtg 34680 tatctggcag atccaaatgg tggcggaccc actgtcgcag acactgcttc ttccgcatcc 34740 ttcggcacgc tgtggattaa atcaccagca aacatgttag ggtactggaa taatccggaa 34800 cgcacccgag aaattctagt tgacgggtgg gtgaacaccg gcgaccttgt ggagcgacgc 34860 gaggacggtt tcttctatat caaaggaaga tcctcggaga tgatcgtctc cggtggagtc 34920 aacattgtgc ccgatgaggt tgatcgcatc gccgaaagcg tttcgggcgt tggtgaggcc 34980 gcatgctacg aaatacccga tgcgcatttc ggagcgctag tcggtttggc cgtaatccca 35040 tcggcagagc tgaacgagtc aacagcgatc gagctcaaac gaaggattgc ggctcgttat 35100 cggcgtgagt cggaatcgat ggcgcgcccg tctaagatcg tgatcgttgc ggatattcct 35160 cgcacgcagt ccggcaaagt catccgtgca acactagcag cagcgctgaa cggagagcaa 35220 ctcggaatgg tcgttcgtga ctgagacagc acgggaaagg attctcacgg ctgtctgtga 35280 ggtgttgtac atagcagaat cagatttggt tgacggcgat gaaaccgatc ttcgcgacct 35340 cgggctagac tctgttcggt tcacgctctt aatgaagcaa ctcggtctga gccaagaagc 35400 tgagatgcaa tccaaattga tggacaattt ttcgattgca aactgggttc gccagctgga 35460 gagttctacg tgacggcgcc aaacacacgt cgcgtcgatc gtgttccctt gagtcgatct 35520 cagcagaaca tttacaacgg aatgttgcag gacaacgatc ccgctttgta ttttatcggt 35580 aaaagctatc gattccacca gctggagctg tcggtgttcc tggcggctct ggaagcaacg 35640 atcctcaaaa accctgggca actttgcgtt cttgaggcgc cctcgacaga gggtgactat 35700 ccggatctcg tgccgaggct gcagttcggc gacatcgtgc gcgtgcggtc cgacgaacag 35760 ccgcagacag acagtcgtga ctacgacctt atgcacgcct ggtctcctga catcctcgcc 35820 aagccactcg tgcggtacac cgtgcggacc gacaagaacg gctttgtggc acgtctcgat 35880 gtcttcaccc atcacatact ggttgatggc ggcgcgatta ggatcattga ggaaaatttg 35940 gcacatcacc ttgacaccga taatcgactc gagatccctt gtatccgaca agctctggac 36000 aaacttgcag aagcacaccg tcgtgaggcg accaaggtgg aggaatcgct acagcgtctg 36060 gccaatgtcg tgcaacgtga gctagccgac gaagtgcgta acggtgggta tggtcaagtc 36120 tcaaacgacg cccccgggaa cgctgcccgg ggagtgcttc acgaatcaat gataatctgc 36180 ggtaaggcat ttgataatat tatcgccttg tcagagacta aacaggtgcc acttaacata 36240 ttggtggcca cggcggcagt agcagtggac gctagcctta ggcagagcac cgagggcctg 36300 ctggttcacg ctgtggacaa ccgcttcgga gatccctatc tggacgttgc tacatgcctg 36360 gtcaattcgg ttgcacactc gatccgtttt cctccatttg cgtcggtgca agatgtcgtc 36420 cgaacacttg accggtccta cgtcaaggca attagactcc gctggcttcg cgaggaatat 36480 taccgacgaa tatatttggc gctcaaccag acatctcaca ttgaggcttt gacgctcaat 36540 ttcatacgcg agccatgcgc gcccggcctt cgccctttct tgtcggaagt accgacggtg 36600 acggatatcg gtccggtcga gggcatgacc gtggcttgtg ttctgaacga agacgagcgc 36660 acacttgatc tgtcgatctg gaacagagta gatctgcccc agggaaagtc atgtacccgt 36720 gtcgcaaaac gaatcgctgc agcgttggaa ttgatggcag cggcgtggga tcagccgatc 36780 gccatgattg tcaacgaatg gtttgggatc agttcagacg gtgccctctg cctaggtaat 36840 gaagttaccc agacaacgcg accactggct ccggcatggt ttctggaccc tgggggaagc 36900 gttcacctga ctgttgacaa acgtcgctac gtccatccat ggattgcctg gctggtaagg 36960 ggcagcgtcg tgccaggtga cgtgctggtg ttcactgacg acaacacgga caagaccatc 37020 gacctcttga tcgcgtgcca tcttgcgggc tgcggctaca gtgtctgtga cactgtagcc 37080 gaggttccct tgcgggcgaa ggcgattacc gaccacggtg gtggtgtctc tgcccgcgtg 37140 atcgatgtgg ctgctaccca gctcgcagtg accccggata acgagcaaag caagctcgct 37200 gacaagctta ttaagcaagc agcacaagat atttcactag cagacaaaac cgcgtacatc 37260 atgccgacat caggttcaac cgggcagccc aaactcgtcc aagtttcaca cgggtcgctt 37320 gcgctctttt gtgacgcggt gagaaacgca tatgggtggg gagcacacga caccatactc 37380 cagtgcgcgc cattgacatc ggacatcagt gtcgaggaga tctttggtgg agcgatttgt 37440 ggatcgaagt tggtccgatc caccgccatg aaaactggtg atctagcgga actcgcacga 37500 gatatcttcg tgcagagggc aacagtcatc gacctaccga ccgcagtgtg gcatttgctg 37560 tgcgaccaca gcgacgcgat tgacgagatc aaccgttctt gccttcgaca gatcgtcatt 37620 gggggtgaag ccgttcgtcc ctgcgctgtc gacaagtgga ttgattccgg tgcttcacaa 37680 ggtatttcac ttatgtcgac ctatggaccg acagagacta cggtcgttgt cacgtatttg 37740 ccgatcgtct gcgctccgat gaccgtcgag agtgacgctc gcctcaggct gggctggccg 37800 atagtgccca acacggtgtt catcgccttc ggcgaactcg ttatcgttgg tgatttggtc 37860 tctgttggct atctcgggat cgatagccgc aacttcggca ctgtgaccac cacggacggt 37920 tcgtgccgtc gcgcgtttgc tactgccgac tgtgtgatcc tcgatgacga gggttttccg 37980 gtgttctccg gacgcaaaga cgccgtcgtc aaaatctccg gcaagcgtgt cgacaccgcc 38040 gagttaattc ggcgtatctc cacggaccct aacgtctccg atgttgctgt cgaagtttac 38100 aacggtcgtc tcggagtgtg gttcgagacg aagctgaccc gcgaaggcgt cgacgatgct 38160 gcggcagcga cacggagcag gctaattctt gcgagcttgg gagtgtcctc gtttttcgtg 38220 gtaggcgtgc cgtgtattcc gcggaagcct aacgggaaaa ttgaccgcga caacctgctg 38280 gtgatgcccc agcttgtcga ctctgtacaa aactatgccg ggtcgggtga gggggcagcc 38340 ggtctcgcgg aaatctggag tcggcaccta ggcagggcta tcctcccgga ctcatcgcta 38400 ctcgatgagg ggatcggctc ggtggatctc atcaggatac ttcccgacac tcgtagacat 38460 ctgggtcggc acctctcgct tctggatcta atcagcgccg ataacgccgc caacctgact 38520 gccgcgcaga cagccaatgt atggatggac gtcggcaccg ccgccgagat agaacgtgat 38580 cttgcttcac tgtgcaggca acgaaacgct acggagttca gcgtcaaaca gacccggaat 38640 agccaccaaa aacaggcgat cgtcgtgctg ggcgcgtcgg gaattttggg cactggcttt 38700 gcccaagcag tcctcgatct aagacagtca ggagtgttgt gtcccgaggt ggtcttggct 38760 acgagggcga gactccccga aggcgatcca tggacagcgc tgcaaggcgt tgatggggtt 38820 cggatcgaac gtatctcttt tgagaatggc cctggagagc tggaggcact aatacgtgac 38880 actgacgccg gaaccctggt gaacggtgtc ggcaatacca acatgctagt gccataccgt 38940 gaactgcggc tggccaacgt agagctggtt tccgcgatag tcgatatatg cgcgagttat 39000 agtaccaggt tggtacattt gtcgtcattc gtcgtcaatg cggatgtcac tgtgcctcag 39060 gtcaccgatc cccgtgaaac gccttatccg tatgcggcat ccaagtcact cgcggagcta 39120 gtcgttgccg gatcaccatc tgcgctcgat ttcaccatcg tgcgcctgcc ccgggtactt 39180 ggcgaagact atcaattacg caattcctct gacattctac tctcgattgt tgatgcctgt 39240 attgcgttgc gcgcctaccc ttccgcaaca gtgacggaag aagtcactac cggccgagcc 39300 gcggcgaagg cgatcttggg cgtggtgtcg gcgttagcta gatcgggtca gctggggagc 39360 ggaatttccg tggtacgtgg cgaggcggtg gcatacgcgg attttctcag tgagttcgct 39420 agcgatgaac tcaatatggc ggagtggaag tatcgactgg atcaaagcga ctgggcgaag 39480 agaaatccac gaaggtggtc ggtgatcgat gcgtggttca ccttgggtat gatgttcgag 39540 atgcgatcct acgcagaata tccgaccatg gccctcggcg tcgagtccgt cgccgagctt 39600 gccgcgccac cagagtcgat tcgagcccta ctagcgcacg gatgttcaca gccactgaaa 39660 tatactggca gatagcaact gctaaacgtg aaacagcaga acaccgaaca taatagccat 39720 cccggtcgac atcatagcct gacctgaggg atgcagcgaa caatagcgac tgaagcctgc 39780 attccttcgc gatgtcgcga aagaacggta cgtccagaag actgtcgcga tacagaagaa 39840 cgcgaaccag agccagttta taatactgat ccatccaggt attccgcttg ccggcaccac 39900 cgttgtagtc atgtccacgc ccagcatcga cgtatggggc gatgtatgat ggccagtggc 39960 ccaatggtcg tgaagatgac tgtccatgat gacgtacatc cagaccatag ccagcatcat 40020 gagagccgga tatgcatatg ccgcccgttc agcgatcctt cgggacgaaa cggtggccaa 40080 gatcacgaac cacgccccaa ctagcccgca aaacaccacg gtccctgtcg ttggtagctg 40140 agcaccccgc ggccaggcca tcactgccat cgcgattgcc atcgcaaaat gcaatccatt 40200 gctcggaacc agtgtccacg gccggcggca ggccaaacac gcgaagccac attcggcagc 40260 gctcagcacg aacagcccgg tgacaaccca acgcagcagt aagtcatcaa tcatgcgagg 40320 tgtcgccgct cggagggagg catctggcta ctgtaggttg gcgttgacca accgacgctt 40380 gccggccacc tacgtggtct gctgttagca tccgtaagct caagcaatgc agactgacga 40440 gccgaccgga acagcgacgt cagctatacg gattcccccg ctgatctcct tgagaaccac 40500 actgatggtg gctggcctgc tgggtaacgt ggtcgccgtt gccgcctacg gactgttttc 40560 gcgaactgag cgttatggcg ctgtcggcaa tccggatccc ggaagtttca tcggcgttgc 40620 cgaacccgtg gggtacttcg gtgcgtcgct gtcaagtgcg ctgtgtcttg gagcattgat 40680 ttacttcgtg atgatggtct ggccgcaagc agacggcttg atcgatgctc aggcttttcg 40740 gattcacctt gctgaagagc gtgtttcgat cggctggctg gcgtttgcac tgacgatggt 40800 ggtggttcag gctgctaacg actccggtgt aacaccggct gagcttcgaa ctggcgcagc 40860 actattcaat gccattacaa cttcggagac ctcacgggct tggatcgttg tgacgatctg 40920 tgcgttgctt gttacgttga cgctgcgagt catcatccga tactccgacc actttgtgct 40980 gctgatcccc gcagtgattg gtgttatcgc gaccgcggtg accggtaacg cagggcaggg 41040 accggaccat gactacgcca ccagcgctgt gattgtcttc gcactcgcca ttgccgcatt 41100 gagcgggctc aagattaccg ctgcgctgac ggaggtgacg ccaagccgcg ctgtgctgat 41160 tgtgcaagtt gtgtgtgggg tgctcgcgct agcgtatgga gccgagctgg tctatctact 41220 tagcccgggc gcggcgatga tcgattcgga cttcggtcgg ctcggtctgg tggccggagt 41280 gctggtgacc ttggtgtgct tctctgactg ctgggcgttg gtcatgggtc ggccgcactc 41340 ggatcaccgg acacgtctta ccgcactggc catgatggcc gtcacggcgg cgacggcggc 41400 aatgtctgtt caaactgcgc cgcgattcct cacccacagg ttcacagcct gggacgtttt 41460 tctgggctac gagctgccgc agccacctaa cattgttagg tttttcaccg tgtggcggtt 41520 cgacagcctc attggagcta ctgccatcgt cctcgggatc ggatatgtag cgggctttgt 41580 ccgtgtgcgg cgtgccggca acacttggcc agtggggaga ctggtggcgt ggttgactgg 41640 gtgtgtcgca ctggtattca ccagtagctc aggcgtgcga acgtacggtt cggcgatgtt 41700 cagcgtgcac atggccgaac atatgacgtt gaatatgttc atcccggtcc tccttgttct 41760 gggcggtccg gtcaccttgg cgcttcgtgc tttgtccgcg gctggtgatg gacaacaacc 41820 cggaccacgt gaatggctaa catggctaat gcactcctcc gttacggcct ttctttccca 41880 cccggtcaca aacttcatcc tgttcgtggg gtcgccgtac atcgtttact tcacaccgct 41940 gttcgatacc ctggttcgct atcactgggg acacgaattc atggccatcc acttcttgct 42000 ggtaggatat atcttctact gggcaataat tggtatcgat ccagggcccc gacgactccc 42060 ctatctggca cgaattggat tgttgtttgc agtgatgcca ttccacgcct tcttcgggat 42120 agcgttaatg acaatgacat cggcaatcag tgccgaattc taccgctccg tcaatctgcc 42180 ctggctggca agcattgacg ctgaccagca tataggtgga gcgatcgcct ggagcgcaac 42240 ggaattacct gtaatcatcg tcatagtggc gctgatggcc cagtgggcac gccaggacca 42300 tagagtcgcc gtccgtgaag accggcatgc ggacagcacc tacgccgatg acgacctaaa 42360 tgcatacaac gcgatgctac gagagttgtc ccggatgcgt cgatagacaa gaccacccgt 42420 tgtcgatgat acgacctgac gcccaggcat gtggtagtca ttgtcgagga tgtgactgtc 42480 ctggtcaggt ccaagattgc ggattaaaac gttgcaggcg tattgccctc cacgaagtag 42540 tgggaaaaat cctcaaggta acatgtataa tcgaaggcag gtaccaggcg gtaggctaac 42600 actttggcgc cgaggtcagc gaactgacgt gacgttaact aaaggtcttt ctctggcagc 42660 tgcgttaaaa acatgttatg ggcacatcaa taacctgaac tgcggggttt cgatctcctc 42720 cggcgtttgt agcatctcgt atcacaatca ggtagccgcc agcgtaggcg tagtagcggg 42780 ctcagtgcag aaccttgtcc aacccgctgt tcaaccaggc atcaatgcga ccaagttatc 42840 aagaaactcg gcactactac gcgcggcggt catggcttga atcttggtgg cgtgatcttc 42900 agcggaggtc aattcgattc tacccattgc accgcgcaac ttagagaaga ccgtatcatc 42960 cagatagatc acggccacgc cactggctcc gtactctcgc acagtacgcg caccattgtt 43020 gcggttgccg tagccgatgt cagcatcggc gatcactggc acctgcaccg tccgaaaacc 43080 ggaccgctga aaattctggc agccaaacca tcatggaaac cggttaccat cagcagatcc 43140 tcacacacca acagcgactt caaactttcc accgcataac gacaattagc atgccctggc 43200 atgacctgac cgaagtaatt acagaagctc atattcgaag tctttacttc gcactttggc 43260 catcacgaag gcaaagattg ctacctcctg cagtggggag agtccgcgct gcaggagcga 43320 tcacgcggtc cttacagcta gccaccttag ccaactaccg aaaaattgct gtttagctcg 43380 atattcgtgc aaatccttat ggtcgagaag gtcaaggcat ggctacgcat ctctggcagt 43440 ggaatccctt gataaaagaa gtttgttcag tctgacgttt gggaaagacc aaaattactt 43500 agccgcaagc tgtttgacac cacgaaaaac gacgaaaacg ccatggcagc accggcgatc 43560 aaaggattga gcagaccact ggaggcgatg gggattgccg caacgttgta gccgaacgcc 43620 cagatcatat taatccgaat tgtccgcatg gtagcacgtg ccagatccaa tgccaccgga 43680 acaacaccca ggctgtcgcg gaccagaatg agatcggcgg cgccgatcgc gacatcagta 43740 ccgcgcccca tcgccaagcc taaatcggca catgccaaag cggggccgtc gttgatgccg 43800 tctccgacca tcgcgacggt gtgcccctga tcacgcagtc gttgaataac gtcgacctta 43860 gcttcgggca gcatatcggc gataacggtg tcgattccta cctgtgctgc aaccgcacgc 43920 gcggcggcct gattatcacc ggtgagcaaa attgtgtgca acccgcggct gcacagtgct 43980 gagatggcgt cggctgctga atccttgacg gtgtcggcga tcgcgacagc tccacatgca 44040 acaccatcta ccgatacgaa aactactgtc tctccccgtg attcgccttc tctccgtgcg 44100 gattcgagaa cgacgtcgca tggcgcattc cgggttaccc aggacggctt gccaattttg 44160 acatggtgct cagcaacaac tcccgataca ccgcatccgg caaacgcgac gaagtcggca 44220 accggacgtg gatctgcata agcggccaca atagccgttg ccaccgaatg ttcagaggcc 44280 gcttcgactg cggaggcgag cgccagaact tccccagaac accacccgcc ggttgacgtt 44340 accgtgctaa cgctcagctg cccaagtgtc aacgtgccgg tcttgtcgaa gaccacggtg 44400 tcaatcgcgt tgatagtttc cagcgctcgg taacccttga tgaaaatccc caattgagcg 44460 cctctgccgg aggcaaccat catagcggtg ggggtagcaa gcccgagcgt acatggacat 44520 gcaatcacca agaccccgag caccacagag aaagcgcgat ctgggctggc tccagccaac 44580 agccaagagg cacccgccaa tcctgcgatg acaaagacca tcggcacgaa cacggccgcg 44640 atgcgatcgg cgaggtgctg cacacgggcc ttctgtacct gtgcgtcctc gacgagacgg 44700 accatcgccg caaattgagt atcgccaccg actgcggtag cctcgatcac taagcggccg 44760 tcaagcactg tggtgccgcc caccacggtg cttgccggcg acgcgtgtac tggtctggcc 44820 tcgccagtga tagcgctcat atcgatcgtc gcagtgccat cgatgaccac accgtcggca 44880 gtaatggtct caccgggcct taccagaaag tgctgttgct ttttgagctc tccagccggt 44940 atagtaagtt ctgctccatt gggcaacaag acctccacat ttttggcacc ccgagcagcg 45000 agcgctcgta atgcactacc agccttggac ttggcgcgag cctcaaagaa ccgacccgca 45060 agaacaaaga cggtgactcc cgcagcaacc tcaaagtaga tcgagtcgct gtgcaggata 45120 gcctgccaaa ttccatgagt ctgccgtggc tctttgtcga cgaagatcgt cgacaaagac 45180 caaccggtgg ccgctaggat accagccgaa atcaacgttt ccatggatgc tgcccgataa 45240 cgcgcgttgc gcaacgcaac acggtggaaa ggccacgcag cccatgtcac gatcggggct 45300 gctaacgcgg taagcaggta tccccagccg gggaatctgt tcgtcggcac aatcgcaaac 45360 atggtcgaca aatcggccaa cggcacgaac agcagcgcag cgacaatgag ccgccgcagc 45420 aggttgcggg catagtcggc gtcaggatca atttcttcga cggcagactc cgcgtgcgca 45480 gtagcacgat atccagcctg ttcaatcacc tgacgcagct catcaaccgc cacgtcgacg 45540 gcatcgatgg tcgcaactcg ggtagcgaag ttgactgatg cgcggacacc gggaatcttg 45600 ttcagcttcg tttcaacccg gctcgcacat gccgcgcaca gcatgcctgc aacatccagc 45660 tgaatacgtc gcacggactc atgattatta ttagtgtcct ccacaagcga agctgtcacg 45720 accttacctc aaatcggcgt tggagcaccc tactagctta caagtgcaac cgcaggcggc 45780 tttgacaaag cacccgcagt tagccgggcc cgcggtccgc gcgttcccgc aaccactccc 45840 gctggcgaag gacaatgccg catcgacgac atgcccatga cctggtacgt agatggaatc 45900 gaggccacca gttacgacta atcgttcaac gttgccggcc acgcggctac atcggaatcg 45960 gcgtcgactg cggggtcgac ggactcctcg accagatcac cggtaaaaca ccacaaccgc 46020 gccgctgtcc gcgtccatgc gaggtaccac cgcaactaga tccgaagtgg tgtgtccacg 46080 gccccaatga tgagcaatgg tcacactccg gtcgccgaaa ttgatgacag cgtcgtagag 46140 tccgtggtgt ggcgggagca tcgccgcata gcgggtcggt agtcgacgac aggtattcga 46200 cccacctgag gtgcacagtg catttcaact ccgacacaaa cagaatcgcc taggatgttg 46260 tcgaagttct tgtgcgtcaa cacaacacgg aagatcggac tgctgacaag ctgccaaacg 46320 tcggtgtcga tcgcagccgc ttcggcgagc gtggtgctcg tgtcgaccag cactgcaccg 46380 gcatggcacg cacagcatca gcccgactgt gatgtcgcag acggaaagag tcgatatgtc 46440 gggtgtttcc gacgtcgtgt acacatctcg cggcatcttg accaggcagc cgttgtccac 46500 ggaggctggt ggctgacgaa ccgcagaacc gtcaacacat ctaccagctg accgctgaac 46560 tgtcgacgga gctaggtgaa tggttacatc tgttagaaac agtttctggc agacaggact 46620 ggatgtactc accgagacat caaagcctgt tacgatcctt agtagaccaa attcatggcg 46680 gctccgctgg cgaaggcgtg gcggctgcta accgaaccgg tgttacgaga ctctagatgg 46740 gcagcgggtg aggtggctac ggcgtttggc caccaattta ccctcgacag aaccggttac 46800 ggcaaacaac cctagcaaag tgcttgaagt ggatccaccc caccgctttg tgtacacttt 46860 cactccaagc ctagacgctc acctggcacc ttgccacgga aggtgctgat accagaagta 46920 tttctgaaac aaacggtacg ggctttgatt tggatgacaa acgtatgact acggccttca 46980 agcgcatggg ccctgggtag cgcgacgtcg tcctctcccg tcttgccgag gctgctttcg 47040 caggccgttg caagggccac ttggaaaatc aactgaccgc tgcttgctgt acaacgcgac 47100 gcgtgtgcaa cgatcaccag gtgatcctgc tagcagtatc cgggtaggaa acgatgctcg 47160 cagtcgccat caccaagcac ggcaattcat cggtcttaca ggtgccgcag cggcccaatc 47220 cacccccccg ccgggacagg ccagcgcggg tcactgtacg tgccgctgga gtaaattttg 47280 ctaacaacct catccgcatc ggcctatata cagacgcagc aaaactgccg tcagtagtcg 47340 gttacaaagt cgccaggtcg gtgtaagcca tttagagacg gcgtcgatga aaaccttgtc 47400 ggagaaagag tcttggccgg tacacaattc gtcggctacg cggaaatcgt caacgttccg 47460 gcgagcgaca cgacacgata gtgttccccg acggggtgag ctggcgcata gggagccagc 47520 gatcccggtt aactacgcga ctgcataagc agcgctgcta acgctacgag tcctgtgtgc 47580 cgttgagcaa gtactaattt cacgcagcgt cgggtagtgt cagcatcgtg gccgttcgac 47640 tcactaaggt cgccagcgcc gaagtgcacg gcaccgcgtc gccaggaaag caccagaaac 47700 ttgctgagtt ggatgtgaac cggggcgcca tcaactaccg ccgcaacgac ttgatggaaa 47760 ggcctcagcc cctatgatct tgttctcgac gcacttggtg acacctcgct gcggcattct 47820 tatggatctg ctgcgcgctg aaggaaggct tgtcggttat gggatttctg cgatacagca 47880 gaacgagaag cgttcgctgc tcagggtggc tccacacacg tagtcgatgc taaaatcgat 47940 catagagtgc ttaataggcg gcgttgtgac cgggcatgac ggtagtgact tggactccat 48000 ggcatccctc accaccgagg tggtagccgc gcattggaat aggaagatca aagaagcctt 48060 tggagccaag gcgatttttt agtgaccacc agattctggc gcaatagacc ataacaagca 48120 atcaccagtg gaaacagata acatggcttg catacggtaa ggagcaaatg tgatgtaccg 48180 taacatggta tctttgaaat tggtgacgaa tctgactaca gtttcgatga aactttgttt 48240 catatcgttt ttaagttgtt ccgtgctgct agcgactggc ttcggtggga aagtgtaagc 48300 aaacacattt gcggcgtgct taccgggagg agtcaatacc tgtctcattc aacaactcat 48360 gagagtggag tgcattcggt taacccatcc aggaccaaga ggatctgcac gaaggaggca 48420 cggtgatcac ggcaggacac atgcaagagc agttccacag aggcatgttc gggaaccgat 48480 gagctcggtc agaacaacgt ccggcgctag gttggacacc acggtttaac cttggcacgg 48540 aatctgatcc cgctgctgtg gtgcagtttc actacgcccg agtgcgatct gtgcagtcgt 48600 actcccgcgc tgtctacgcc cacgctcatc gtgtcgtgtg ggggaagaaa gacatcgtga 48660 tcccactaag cgctgggagc gccacccatg acgcgattgc tagatctcgg ctcgagatcc 48720 tcgagactgg ccatatgttt ttcttgtcag atccgtacgg cttcttcgcg gtcgtcgagc 48780 agtttctgca atcggtggtg ctgcaaccat cctcttgatc gctgatgcgt tcaaactttc 48840 agctctcatg cgcctgagtg gctagctcag cccaggatca gcggagagcc gacgtgagga 48900 tagcgatgcc gcttaacacc cctcttacac aattcttcta gatcgaacac cccgtcctgc 48960 ttgcaccgat gaccgaggtg tccggggacc ggttggccgc gatcgtgacc gcggccggcg 49020 acctcggtct catcggcgga gactacggcg acgcaaactg gctgcagcac taatccggcg 49080 aagcgcagca ggaaaaggtc gaaatcggat ttcatcacat gcagcctcgc ccttaaccct 49140 gagcgctaaa cgcgatacta gcgcggcaac cagcaacgct ccatgttgtc tttcactgat 49200 ccagaggcat tcgccgtccg tattcaccaa gctaatattc cactctcatc tgccaagtgc 49260 agacactcaa gcaggcacgc tttgaacacc gaagcggaca tagtcatagc ccaaggcggc 49320 gatacaggtt ggcatgaaat aggaggtcgt tcagccttca ccctggtgcc cgacgtcgtc 49380 gacctcgtcg cctaacagtc ggccaaaacg cttgtgttgg ccacaggcgg tatcgccgat 49440 ggtcgtgacg tcaagaccgc accgaccttc ggtgactatg gtacgccggt cgggagccga 49500 ttataatcca gcactgagac gccggttatg ccacaagctc aatagccaat tatccaggac 49560 aacagagaag acagtgcccg gacctgagtc tatggcattg tgcggcaacg gaatttatcc 49620 gaaattacta cgcgcagctg gttattaacc cgttgatcca agcatggcat ggcaatgagg 49680 atggactgtt tggcgttcct accggagacg gtgagcgcct ttgagaaagc gttcgtcgag 49740 tcaggactgc gatgtcgcca cttcactagt tggcgagact ataggactca ttcacgaagt 49800 tcgcaccgcc gcactgctgt cgctagctcg ccatagttga tcaaccgctc gtcgattatt 49860 agcccgaccc gggcgagata gccagccgcg gctgcgtcga ggaccgttcc cgtgtttatt 49920 gcggcacagt atccttcaat aacaccttaa tgcagaggta aatcactcgg aggttagcaa 49980 caaccggatg gtcgcctact aaatgcgctg aataagaatc acctcacaac ggcacgtagc 50040 tgcctaggat gggctgtaat gcagcgtgca ttgtcagcat ggacatcagc tcgaagctcg 50100 tgggtgcacg tcgccgcatc tgaccatgta ttcctcgcac ttgtcctcat agggccacat 50160 ggcgccttcc acgcaaagac ttatctcgtg ctctcgtcca tcgaccgaca tctcatcgaa 50220 cagatttcaa acagtggcga caacggaagt gctaccagca gcttcgcctc cacctgatgg 50280 cgaagggtgt tcaggtctcg cgtctactcc cggagatcac ctttctggac ccaccgggta 50340 caagcactcc catgccattc cgtcacgaac cacggttacc gtgatcacgg tgtaggcggg 50400 gccgctgccg tgcgcttgat tggtgtacca caccagccgg gcttcgtcgc cctcgaccaa 50460 cataggcatc cagcattctc gaaatgcgtt ctcgaactca ccttccgcgc acccgccgta 50520 ccttgtgcat gaacagcacg ctgtgacctc ccaccccctg acgctggaac cggagaacac 50580 catcgttcaa acggacgtta tatgccaacc gtttttggtt tcaacgctgg gtctacatat 50640 gcacaacaat gcccagtggt gacctagacc ggtgcgttga gaatctgatt tcctcaagta 50700 ggtaaaaatc ttcacgtaac agacgttcct catggctcga ctcgacgtgc ccgacgtcct 50760 cggtggcgaa gccgtcatga tctggacact acggctgcaa ctcggtggca tgatcgaacg 50820 gatgatccgc ggcacatacc agcaaaatag ccctgccggc cggcgaacgc gagttagccg 50880 taaggcgaat cgcgcagatc aaccactgcg tcgcgtactc tagctttcgg gaccaattgg 50940 tactggacag ccgatgtctc agcggggctt tacgccaacg tcgcctcgat ggacaaaacg 51000 ttcttcgtgc gtctacggga cctgtcctcc aatgaggaaa ttctcgatct cacgcttgtg 51060 cgtcgcggta tagattgcgt gaacatcgcc atcggtcgac gaactgctag ccaccacacg 51120 gttggtgcgc aaacgccttg acccgaccca gccggtcgca acgtcgtcct cgagtgcgcg 51180 cgccgggcga tgcaagcccc caccgcaagc aacgcacaag atcggcgctg gctggtgatc 51240 accgatgccg acaaacgtgc ggcgatcgcc gagatctagg gcagtgtcga cgctgagtac 51300 atcactacaa ccgctaaaac cttctcagat cagcagacct gacgcgagta tagcaacatg 51360 gtgagtctga ccaaaacgct ggaccacgtt tccgtacaca tcatcccttg cctgcagtgc 51420 cgtttccatg acgccgatcc gctgttcgag cgtggcggga tcacctattg ggacagctgg 51480 atagaaagct gatgcaatcc agcacagtgc gattccacat ctacgcatcc acgaagaaaa 51540 gtgggcaggt actgcgtcca ccggcgccgc caaacgcacc acggccacgg gtcctcaagt 51600 ggccaaataa gagcatgtaa aatcctgaaa gaaggcaact aggcgggtga ggtctagtcc 51660 gcacttgcat cttcgaaatg cccaagtact tgctgtccgg cggcaagagg cggtcgtggg 51720 aaactcgttc ctgaagcgga gatcaacaag ctgtcacgat atgtggcggt cagcgcgcca 51780 gtgttgtccg gtgccggagg gctattacca attcgaagag tagctctacg gcatcacgac 51840 gctgaccttc aacgagacct atgagcgcag gcttggctac gccggcaacg tgcggcggct 51900 gacctagacg tcagaactgc acgccgtctt agttgtgcct gttctcacaa caggtttctt 51960 cgcacagctg tacgcagcaa ccgtcgtcgg tgaaatagca gattttacag gcaaggtggt 52020 gtcagcacga tgaccgccac atgaaaggaa caacaatgtg ctggatatgt gaccatcagg 52080 gcaacaccaa agacaattac tggacgatgt tgtaatacgt ggaaaacgac cgagtgctct 52140 acacgtatat agtcgtcctg acccatcatg ggttgcccga attcttggtg actggcgtct 52200 aaccccagca aactgcgcga atgttgggcg gcgttgcccg atcagctccc gttcttcgcc 52260 caccgaatcg cggtgaataa ctaaggttaa gcgtcagcac cgtggtggaa gtcgtcgcga 52320 ttgagtatcc cgacgcgcac atggacaccg cgactgtgat ttacagcagc acagtcaaag 52380 cattgcagct ggtgtggact tacagacgta gtcgctggcc ctgggaaccg ggcttcaacg 52440 atggtcgaag tatccagccg gtgctaggcg tacggtccac accaaactct tgatctgctc 52500 cagaaaagtc tagagtcata tcggtccgtg ttgtccccga tgtcgaacta cgcaaagcag 52560 ttgcgcatgg cttatttgcg tgtgacccgt ccacaaatcg ccgtgtccga agcagtgcac 52620 acgcccccgc acgccaacat taaaacgagc cgtaatgccg ttccgtgttg aactgcccgc 52680 agtgtcccgg caaaccgtgt acgacgtact gcaatggcct gactaccaca agtctggtaa 52740 ggagcgaatc tctggtaagg agcgaatcca gtcctcgggt tcggttgctt gctacgagtt 52800 acaggccgga aagaaccacc atcacattgt gtgccaatac tgcagagcgc aatcgcagac 52860 gctaattata cgaccggtga ggcgccgtgt ctctgactac ctcagaccct aacagcttcc 52920 ctattaagga ggctgaagtc atctactggg tcctatgccc ggactgttcg acatcagaca 52980 ctcccgaaag gaatgccgta ctcgaggaac acccgcccat taatgaagcc aacacggaaa 53040 acgttgagag cggcggcccc ggttatcggt cacatcaaat gccccgtcca gaaagataaa 53100 gatcccgtcg agggcgacag gaaccaggac tggtggccga acaagctcaa ttctcaagat 53160 tctgcatcaa catcccaccg tagccggccc tatgggcgtt gttcatccgg atggcgtgac 53220 acgcacctta gacacctacc gcatcaaagt taaggccgcg gcgcaccggg gccggtaggc 53280 agcggttcgc gtggctcaac agctggcccg acaacgccag cctaaacaag gctcgccggc 53340 tgctgtggcc ggtcaagaag aaaatacagc aagaagcttc tcgtgggccg acctgatcgt 53400 cttagccggc aactgcgcac tggaatccat gcgcctcaag agagctttaa ttttcggcgc 53460 agtctaattt acgtgaaccc gaagggtccc aacgacaatc cggactcgat cgccgcggcg 53520 gtgggtatcc gcgagacatt cggccgcatt gcgatgaatg aagtctaaac ggctgcgctg 53580 accttcgaaa gccacacgtt cggaaagacc cacgacgccg gcgacgccaa actggttggc 53640 cccaagcccg aggccgctcc gttggaggag atgggcctca actggaagag ttcctttagc 53700 accggtgtga acaaggacgc gatcaccagc ggcatcgaga tgagtgtgtt acatccactc 53760 cgacgaagtg agacaacagc ttcctttaga tccttgtacg gcaacaagta tggagttgac 53820 gaaaagtcac gctggggcct ggcagtacag cgtaagggac ggtgccggtg cggcaccatt 53880 cccgacctaa ttcaactcat cccagcagcg tggcaacgta cccccagcca tgctgacgac 53940 cgacctgtcg atgcggttcg acccgatcta cgaatgaatt atacgctgct ggttggagca 54000 tcgtaggaat tggccgacaa gttcgccaag acctagcata tgctgatcca ccgaggcatg 54060 gggccggtcg tccgctacct cagaccggct agctcccaag aaagtcctgt tgcggcaaga 54120 ccccatccct accatcatgt acgacctcat ctatgcagcc gacatagccg ccctaaagag 54180 ccagatcctg tcgtcgggtt tgattgtttc gcaactggtt tccaccacat gggcagctgc 54240 gtcgttccgc agtagcgata accgcggcgg tgccaacggc gatcgtatcc tcctgcagca 54300 acaagctggg tgggagatct atgagcccga caaactagca cgtatgatac gcaccctggt 54360 aagggattca aaaatctttc aattcctctg cgaccggtaa taccaaggtg ttattcgctg 54420 gccttatcgt gctcggcggg tacaccacaa tgaagaaggt ggcattaacc actggacccc 54480 cgttatttat ggtgctcttc cggctgagcc gcgcggatgc gtcgcaagaa cagaccgatg 54540 tggaatcctt tgccatactc gagccgaagg caaatgactt ccacaactac ctcagaataa 54600 ggtaacccgt tgccggcgga acacatgcta atcgacaagg ctaaatctta atctcttgac 54660 gcttagcact cccgagatga cggtgttctt tgggttttgc acgtacgcgg tacgaactac 54720 aagcactcgc ctttagacgt gttcaccaag acctctgggt cctcaaaagt cgccttgacc 54780 aacgacttct tcgtgaattt gctcgacatg agcacgacgt gttcgccgtc ggcaaccgac 54840 gacggaagtt acgagagcaa ggatgccaac ggaaacgtgc attgacgggc agccgcgtgg 54900 acctggcatt cgggtgaaat tcagagttgc gcgcgatttc cgaagtctat ggcgctgatg 54960 acgcgcagca gaagttgtgt gcaggacttc atcgctgcgt gcaacaaggt gatgaatgct 55020 gaccggttcg atctggcctg acggccacac ggcaccgcag caaactgagc ccggcgtccc 55080 agcggttcga aatcccccgc acaccaggta cgctggggtg ctatgtggtt gacagcagca 55140 cctgctgcgg cgagatttgt cgttgcgagt gtgatagctg cgagttgcgc tgcgtcgacg 55200 ggtgttgccg gcgccgatcc gcagtcgccg tctgcaccga agacaaccat cgaccacgat 55260 ggcacatatg cggtgggaac cgatatcgcg cccggcacgt acagctccgc cggacctgtc 55320 ggcaacggga catgttattg gaagcggatc gacaaccccg atggccctat cgataacgcc 55380 atgagcaaaa agccgaagat tgtgcagatt gaagcgagta acaaagcatt caagaccacc 55440 ggctgccagc cctggcagca aacgagtaac accaccgtat caacggatct ccccgggccg 55500 atcgcaggaa tccaactgga aagcaatctc gggatcctca atgggctgct cgcctcaaac 55560 ggccagcaag tgccgcggtc ctgatcgcta ctggccacac ccagacaact gaaccggttt 55620 ctcggttacg gtgctgccat ggcaagtaac gggcaacaaa ttgtcgtcat tggtgccggc 55680 gtgagtggct taacatcggc cgtctgtctg gccgaagcgg gatggccggt gcagctgtgg 55740 gctgccgcaa tgccacagca gacgacctcc gcggtggcgg gggcggtatg ggcaccgcca 55800 cggccagagg aacgtgcctc tacatcgctg gcttggacag gacactcact gcagatattt 55860 cgtgaactgg ctaacgaccc cagcaccggg gtgcgtatgg cgccagcgtt gaccgttggc 55920 gatttacccg gggcgaacgc gatggggctt gctgccaagc tgatccccga cctgcggccg 55980 gcggacctgg ccgatctccc tgacggcttc ggtgccgggt ttttcggcac catgccaatg 56040 atcgatatgc cccaatacct cgattacctg acagcgcgac tggcggcagc cggctgcgaa 56100 ctcgaaactc gttcagtacg gtcgctagct gaggccgcag acactgcacc gataattgtt 56160 aactgcactg gtctcggcgc agcagccctc gcgaacgatg acacggtgcg tccattgttt 56220 ggtcaacacg tagtcctcac aaatcccggt ctgcagcaac tctttttgga agtcaataac 56280 ggttcggaat ggatctgcta cttcccccac cctctgcgcg tggtgtgcgg cggcatcagt 56340 atccccggcc gctgggatac caccccagac cccgcggtga ctgaccgaat cctgcaacgc 56400 tgccgaagaa tcgaaccacg gctcggcgag gccgcggtga tcgagacaat taccgggttg 56460 cggccagacc gtccgtcgcc gcgggtggag gttgagctga gtgggtccgt gcggtacatc 56520 cacaactacg gccacagcag cagcggcgtg accttatcgt gggggtgcgc acgcgacgtg 56580 gtgcgccttg tcagcgactg atcattgacc ccgagttctc agtcgcaagt gcggcgccca 56640 gcacctcgaa tcagcatcga cagcacccag ctcacaattg acaacacgat cgcagcccag 56700 attgcagtcc accagaagtg gtcgatttgc aatccccagt gggtggtgtt ccccgtgatt 56760 cgggccgtta tccacagcat caacgcgtta acgacgacgt gaaacaagcc gagggtcaaa 56820 atgtacaacg ggatcgacaa aatttgcacg attggcttaa tgatcgcgtt gaccaaaccg 56880 aagatcaccg ccaccacgaa gatgatgcct actctctgca aggtcgtgtt gccaccgaca 56940 aagctcaggc cgtggacgaa ctgggtgacc acccacaacg ccaaactggt caacgcagcg 57000 cgaacaagaa aaggacccac ggcgggagat cttgccatcg aacgctctaa tacagagcgt 57060 agaaacgctg cacattcaac cagccaatct ttacgcgcgc ctcgtagctg attcggtgcg 57120 ggtacgcagc agcttggtgc tttccggcca ttcgcagttc caatacgggt agtagctggc 57180 gaacatgatt aagtcggaac tgagcacgtc gaccacgctg ggcaggatcg gctctctcag 57240 ctcacaggta acccagatgt tgccttcggt cagataaccg cgcggatcac agcgccaacc 57300 gctctcaacc tagttttccc acttcatcgt aatgatcgtt caggcgatca atgaagaatg 57360 ggaccaaccc gcaccgactt ccatgaaaac gactcgcaac tgcgtatggc gctcgaccac 57420 tccgtttgag acgagcgcag taatcgccgt cacccagtct aacggaaagc taatgcaggg 57480 cacctagatg tagttcttga atcggtcaac accaatctgc ggcaaatgga taccgggcgt 57540 gaatgctgat cgccatccca cgctctacgg tggctgcgta aaacgggccg aggtaggggt 57600 ggtcgaggtt gctagcgttc agaaccggcg ggatcaaagt cacagcgatc ccaagttcct 57660 tgaccccgtt cgtgatgtcg atagccacct ggccgcgttc catggaggtc acaccaccac 57720 cacgcaacca accgtttgtc ggcgcgcaat aatccccgat ccactggttg tagaatcggg 57780 ctaatctggt agcgaaatca gggtcatcga gtctgagtat gcagaacccg aggctgggat 57840 acaacaccat catgtcgatg tgctcgcggt ccacatctct cagcacaccc tcggccgacc 57900 tgcagttgat atcgggtacc ttgataattt cgtgctcggg ctggcaacca gcgctggagc 57960 ctctggtctt caggggtagt tgcggccttc gagggtcaac cgcagccgcc tgtcggtact 58020 gggtttcacg ctattaagtc aacgcttgat ggcttaatca ccagtgaaga attctcggcc 58080 gacgtgtccg tcgacatcca tgattctcat gtatccgaaa cgtactcggg caagtcgcgc 58140 atgcgccatc gcttcgtgta cgcaacgatg cttccgtgac aattcaacgt gatcactggt 58200 gatccacgta actcgttcat tgcggcaatg ttgggccatg ctacggatgg cttcgattac 58260 ttcatcgtgg tgttcgtcta tgacgacatc gcaaataatg tctaccacag caaggccgaa 58320 gtcgcgttca ctaccacggc caccctgatc atgcgtccgg tgggcgcatt gttgtttggg 58380 ctctgggctg accagaccgg tcggcaactc ccgctgatgt tggacgtgat gttctattcc 58440 gtggtgagat tcttatgcac gttctcgcca aacttcaccg tgctggtgat cctgcggttg 58500 ctccacggca ttggtatggg cggcgaatgg gggctgggtg cagcgcttgc gatggagaag 58560 gttctcgtcg aacgtcgggg ctttttctcc ggactgctgc aggaagacag cgcgtttggc 58620 tgtttgctgg taagtatggc atcgctggtg gtgatggatt gattgcactt aaccatggcg 58680 atggttgttc ggcctaagca tcatcccggc cctgattagc ctggtcatcc gttaccaggt 58740 gcaggaatcc gaggtatgag aagccgtcca ggccggatac agctgactac tgactaacac 58800 cagaatccgt aacgtgcctc gctgcgaggc gatcgtctgc cggttcacct atctggtgct 58860 gctgatgatc gcatccagcc tggatgagcc acggcaccca gtacatctac ccaacatttt 58920 ggtagcagct tccaaccacg gtgccgtcct gtccagctcg accgtcaagt ggatcgtgat 58980 ggtctacaac atcggcacca tcatcggccg attacacttc ggcacgctgt cacagcggtt 59040 cagccgacgc aataccgtcg tgttctgcgc gctgctagca ctgcctatcg tgccgctctt 59100 cgcctactta cacgccgcgg tgatcgtggt gatgttgtgc ctcggctcct tcctgatgca 59160 agtcagtgtg cagggtgcgt ggagtgtcta tccccgcgca cctgaccgag atgtcgcagg 59220 acgccattag tggccctcta cactggcgtc acctaccagc tcggcaattt gctcgcggcg 59280 ttcaagctgc ccatccaggc acacctggcc gagccccacg gctacccttt cgcgttgacc 59340 ggtacgatag tgtcagtttt acttgccgtc gcgatactga cgctgaccag caaagacgcg 59400 actggaatcc actttggtac tgccaaaacc acttctgtcc caaccgaagt cacggtaccg 59460 aatcggtatc gctgagcgca tggcgcagga gatgcatcgc cacggtcgtc gaacgctcac 59520 ggatgtcgga ccggttcccg ggtagccgta gtgtccgagt gagcgtcgga cctccgtcgg 59580 caagcatcac ggtgaagcag acagttccaa ttggcttttc cgcagtcccc cctcccggac 59640 cagcaattcc gctgatcgcg gcggccgtat cgacatcgaa gcgctgcagc gcacccgccg 59700 ccatcgcttc gaccaccggc tcggacacct ccccatgctc cgcaatcagc gccgggtcga 59760 cgccgagtaa cgtaactttg gcctcattgg agtaggcaac caaggcaccc gccacatagt 59820 cagatgagcc aggccgctcg gtcagccgtg ccgccagcag ccctgcagta catgattcgg 59880 ctgtcgcgat cctccggccg gccagtaggt gggcgatcag atcatccaca cgagcaccat 59940 cttcggaata gagctgatgt ccgtgccggt cacgcaataa ctgcgttaac tccacataga 60000 cgttgacgac gtccggttcg tagcgcgtca ccatttcgat ctccccgcgc cgcaagcagg 60060 tggtgatctc gagcgcatca aagccaggga tggaggcctg cgcatcacgc agcgtctcgg 60120 cgagccccga ctcggaaagg ccgaacatcc gcagggtctg ctgccggtaa atggttcggt 60180 cggcgatcgc ttcccgcgtg gctgcggtca tgaccgcgcg acgccacatc ggttgcagct 60240 cacttggcgg tccgggaagc accatcaccg tcggcttacc cggcactacc aaacccggcg 60300 cagtgccaat cgggtcaagc acctgcgaac cggcgggaat catcgcctgc ttgcggttgg 60360 cggcgcgcac cgcctcaaag tcaccgggat tgaagcgcgt catcagtgaa ttgagaatgg 60420 cggcaatttt gttctcgagc tcgacatcca acaccatctc acgattacaa aaacgtgcca 60480 ctacctcgac tgtcatgtcg tcggcggtgg gtcccaggcc gccgctagta acgatcaggt 60540 ctacgcctgc ctctgccatg aagcgcagct gcgcctcgat gtcagcaggg caatcaccac 60600 agattgtaat gtgtgcgagc ttgacgccta gctcgagtag ccgatctgcg agccaagggc 60660 catttctgtc tcggacacgg ccggtgagga tttccgttcc agtgaccacg atgcctgcac 60720 gtgcgctcac caccattagc ctacgcatga actagcctgg ggccgtggcg aatgcgcccc 60780 gaagtgacag aattcgctat gacaaagtgc ggcgacatgg acaccgccta ctagatcctt 60840 ggtggcggtc cgaccgacct tctggtcatg tcggagccgt tcgccccgat cgactcggtc 60900 gacgatgagc cgccaatgta tgattttaca tcgacgccta gcctcgttca gcgaggcaga 60960 tccagttaac catcgcggag tcggtctctc gtcgcggctt ccttcgatga acctgtcaag 61020 atcgacgttt tgggccgaga acgcgatcgc tgtgatgaac gcagttggat gccagcaggc 61080 aacgatcttc gcgctgaggt ttccctgcga tgaacgaact tgtgctcgac gctgacgctc 61140 acgagtgggt gcgcaacttg gcggtcgtca acagtgctgc acacactggg ggcgccttac 61200 tacccggtcg gcgcccaggc cgcatcgtgc tactccgttc acgacggtag cgctcgaacc 61260 cgattcgttg gaacagggtt tcgacatgtt ggcgaccatc gcaccgagtt ttgctcacga 61320 cggcgctcca cgcctgggtg agatctggcc agcaaccgta cggggccacc tagcatggct 61380 agcgccgtct cctaagatcg tgaccagaag gtgacatacg agaaaaccct cgggcgcact 61440 agcgtcccga tcttgatccg tcatcgtgtc ggttcgactt gcattcccgt tgggcacggt 61500 ctttacctgg ccaagcagat tgctagatcc cgcttcgtcc aagctaccgg gcgccgatgc 61560 cctcatatac ttgggtggcg acaccgcgtt gatgcttgac gagatcgaag agttcatcac 61620 tggtgtgcgg ggcggattcg aggtcgaacg cgtactgagc accattgtgt tcaccgacat 61680 cgttggcgtc actgaacgcg ccatgctgct cggtgataaa tcagtggcgc ggcctgctgg 61740 acaaccacaa catccatggt gcgacacgaa tcgcagtggt tcggcggtca cgaagtcaac 61800 accaccggcg actgaggcaa ctgatgtgtt gcgaggttcg ctagtaccag tgccgcgatc 61860 gcctgagcaa acaaaatcgt gaacgctatc ggtgtgctgg acatcgagat gcggatggtt 61920 attcatgtag gcgaagttga ggtgcgcggc gtggttaacg atacgctttt tcctgccgag 61980 cgatcaccgt tgtgcgacag tgcgagggtc ggtcagttag gggaagtatg gatatccttt 62040 ctgatcgtgg cgccgaagta cgtagcctcg gtggcaactg atttggcggc tgtatgcgtt 62100 taatccacac tcgctcccgc ttaagctgat cccgggcgcc ggtctgcgag acaatgtggt 62160 gataatcaag tagtaaggtg cggcaagcta acgtgagcaa gctcgatgcg atcgccaacg 62220 cagccaatcc cagctgcgcc acggtggcgg cgttgccacg gcaatcgctc gcgccggcag 62280 gccgtaactg cagcaggagt cgattcggaa ggcgccgatc gaactcggaa aagcggtgaa 62340 gaccacagca cgcgaaatgc cgacacacta cgtgattcac acagtgacga tcgaggtagg 62400 aggtctgccc gcagccgaaa tcatcacctg ggctaccggt tcgaccttgc gcaagggcca 62460 atgagctcgt ttgacgctcg cgggcgctgg tggcgtttgg cactggtgtc ggcagcttcc 62520 cgctcgaaga cacggggcgg ctgatgatca acgctgttcg acagcatcag gccagttcgc 62580 tgcagggaat ggtgttcacc atgcacggtg gcaaaactga gcaggcgttc cgggccgtca 62640 tacagggtat agcgtcgatc ggatgttgcg ggtcgatcgc cgacgactta ggacagataa 62700 cgctcgatga aatccacctt ttgcggcata acactcggca accccggacg cgggtcgacc 62760 ttgattactg cggtgcacaa gcagccacgg cctccaccgc acgctgcacc accccatgac 62820 ttgctcccag atatcacctt cgatcatacg gccagcacag agacctaatg acctacccag 62880 taaccctgta ctcggcttga ggaaggcctg gcagtattcg agcactatgt gggttctggt 62940 acaacgcatg tcgtcagcag cgatgtagtt cgattgccag gtggtcggag ctatccagcc 63000 cgacctccaa aaccttttca cgttcgtgga tttcacccac agcgacgatg gcgatcgtca 63060 ggaccgccag cacggcgact acggatggca gataagctct ggaatccacg gattctcgct 63120 gacgaacagt ccgctgccga cgttaacgca ccgatcctgg tggtgagtta cttcaccctc 63180 tacgctgata ctgtagtagg gccgtcggcc gtcatggaac acagccgctc tgggtgctgc 63240 cgctgagcca ttgatttcgt ctgtcgctgc gacattacgg gcactgggtg ctcaggtgga 63300 aattggtgtg ttcggcgccg acatgcaggt cgaattggtc aacaacagtc cgtccccctg 63360 ttgctggagc tgtgaccgta ccttaccgtt ggaggcgttg gtgaatacgt ggagagaagg 63420 ccaaaggttg ctagacacta gaaacttgtc ccggtggtca agggttgatg gcagccacac 63480 ctgaatttgg gtcacttcgt tccgacgacg accattggga catcgtcagc agtgtgggtt 63540 acaccgctct actggtggca ggctggcgcg cactgcacgc ggtagggccg caaccattgg 63600 ttcgcgacga atacgcgaag tatttcatta ccgcttcacg agacccgtat ttgatgaatc 63660 tgctggccaa cccgggaact tccctcaatg agaccgcgtt tcctcgcctt tacggcgtgc 63720 aaactcggtt cttcgacgac ttcttcagct ccgctggtga cacaggtata cgacaggcgg 63780 tgatcgtcgc tgccgggtta gactctcgag catatcgcct caaatggcca aacggtgcaa 63840 cggttttcga aatcgatcta ccgaaagtcc tcgaattcaa agctcgcgtg ctagccgagc 63900 aaggcgctat acccaacgcc ggtaggagcg aggtagcagc cgacctgcgc gccgattggc 63960 ccagagcatt gaaagcagcc ggcttcgatc cgcaaagatc cagcgcctgg tcagtcgagg 64020 ggctgttgcc ctacttgacc aacgacgcgc aaagcgccct attcactcgg atcggcgagt 64080 tgtgcgcacc gggcagccga attgccgtag gcgctttggg gtcgcgttta gaccgcaaac 64140 aactcgccgc gctggaagcg acccatccgg gggtgaatat ttctggtgac gtagacttct 64200 ccgctctcac ctatgagcca aagactgact cggcgcaatg gttggctgcg cacggatggg 64260 ccgtagagcc cgttcgtaac accctggagc tgcagactag ctatggaatg actccgccgg 64320 acgtggatgt gcagatggac agtttcatgc actcccaata cataacggca actcgatgac 64380 gaagtttccc ccaccgttag ggtcctttat catagattgc ttaggagttc aggctgttcg 64440 tggtcaggat ccaggccacc ggtttgaccg ggataccgca atctacagtc cgcctgacca 64500 aacccggttt gagcatacct ccggtgattt gacgcagccc cagatgacta gggccatagc 64560 gcttgacaca ctggaacaaa aatcactggc cccgtcagga cactccatat tcaactagaa 64620 cgtgtttcag ttcagttagc atcgatccaa cgccccaggg gcaggcatgc acactgccat 64680 tggtgacaaa ctcggtatcg aatttcgaat ttgctcctcc acccactgcc acaatgtcgt 64740 cgctgtcagc aaggtcgacg gtttcgtgat gcttggggcg gtcagtttca cactcgaaca 64800 actaaagtcc gagctcaact ggattgatga gcacgtccgc aaccatcccc tactgggtcg 64860 cgatatcgtc accccgaaca agtaggagag catggattcc cacctttcgc cgaatgaacg 64920 ctgcgctcga tgatgtcgca aggacatttg gattttacac gcaaaatgct cgcagatcat 64980 ggtgtcccag tcaaagatag tgacaaggac agtttgcagc tgctcggctg gaccgaggcg 65040 atcgccattc cccaggtcga aaaatgacgt tgcggcaccc gaagatgacg atggttgcca 65100 acgcgcccgg taccccaacc accgacatga tcaagcacat tgacgactct agtcgcaaag 65160 tagccgcatt atgcggcttc cccacgtaga ctcaaaaaca cgtcgacatc atcatcgcct 65220 agaacagcga gacgggttgg acactgcggt gaagtggact caaattgtgc tgtagccaca 65280 agtcgtcaag gagatcgctt caagatcgat gttggctgcg tgtggtatcg acagccgcca 65340 acagatcgct gcggacctgg tcctgtaggg cacctaagac gcgtggacgg gctcacagta 65400 gctgatggtt ggggaacccg cgaacaccct aatccagcaa acggcataat ataaaaatat 65460 ataaagacca ccagctacga caccgtcaac agctgttctt tcaccgacaa accgactcgg 65520 atgctgctca acgactggac cgaggcctgg aacacccgca gccgctcgtg tattccacta 65580 ccagtgcatg gtttccgata tggccgttaa gaccacgcac aatatacacg aacgaaatcg 65640 tcggcgtggc gttcaagcca gtcaggcagg tcatcggaca attcaccaag gtggagaaga 65700 cgaccacagt catcacgcgg tgggttaagg agtacccggt agactacgat gagggtggac 65760 gaactcaatg tcgccactgc cgccgtctat cagctactct aattcgtcgt attcaccttt 65820 gccgatgaag atttctttcg ccttgtcgac cgcgtgagtg gcgatgtcaa tagagttctg 65880 gacgatatcg ttggcgccac ccgcgatgtc acctttgatg atgtcactaa cgttttcgac 65940 aatgtccgaa gccttctcga cgaaattagt cgcaatgtcc ctggccgcgt tgactgcgtt 66000 tttaggatcg aaggtcatct gcgtctcctt tggctgcaag atcttcggta cgactgtagc 66060 tttggcaaag acctgggttt ttcggcgcgg tccggagctg acatcagtgg gtttgctagg 66120 ttgcgccagt atttttccgg catactcggc accgtagcgc aagatttgca atatttgttt 66180 cagcccgaac ggccatggcg attccaagta aactcgacca taaccctgcc agcccaatga 66240 ctccccacaa cgtggctgtg acgatcggtc atggggacaa cacggcaagc atcgacacga 66300 agaagatggc cccgacatac cacgccaaac tagatcaatc agacaccagc acaaagcgca 66360 gccatctcgg gatcggtgaa ccgttgcgca tatctccaaa aataggctgg tcgttagcct 66420 gcaggcggaa aaaacccttt gtcggtgaac cagcccggtt gccacccttg accacccaga 66480 cagagcatgg gcagaccgtc agctgactgt gccgctgctt gggtcttcgg gcacggcgct 66540 ccagcttgct ggactccgta taacgggtat gaaatcaccc agtatccggt gtttgctggc 66600 gggaactggt tgggaggagg gaaatgacac gcttcggcct ggccgctggg gcctcgtcca 66660 aaaatatatc gctcccagct aaaacacgga gcgctcagcg aagcatcata actcatgccc 66720 ggtacgtcgc catcgtaatg cggattagcc gccgcgcgcg gcgccgaatt gaccgcgcca 66780 ctcgcgatcg cagagatggc gagtagttcg cgaatcatgc ttccaccctt cgcactaatg 66840 tcacctgacc cccaccaagc cggcggtggc gtgcaccaag catatcgagt gcgccgcaca 66900 ccacaagacc gacttgtaga accgggtcac cggcacaacg acgtcggtag gcggggtggt 66960 gctgttaact agcttttcta tgcatacgga gaatacggac gacgtaccca aaaatcaccg 67020 gcaacgcttg tcatttgctt tggtagtctt gctctgatgc ttgccagccg ggtataacaa 67080 tagatttatt ggcataagaa ttgttctatc gataagtggg ctatactatc aacccaagta 67140 atccacccaa ccaattcctc aacttaatct cccggattcg attttcctga cccagaaatc 67200 tacaccgaac agctgtcggt gtaggaaccc gccgagatgt gccaagccga aacgatttaa 67260 tgaaacgagc agccaatcgg aaggagcggg ttttatgacg atgattattg acgtggtgtc 67320 caagcacaag gacgtttcac tgtcacagcg gcaccttctc caacctggaa aagaccgccc 67380 tggcctgcta ccaagaaggc atgaacgacg agcaaatcag caggggcaag ttggttctgc 67440 tcaacataga cgcctcgcag tacactcggc tgcacaaaat catctcgccc ggtttcattc 67500 cctgagccgc tgagcaactg cgtgatgacc tgactcgagt gggcctgccg catcgtcgcg 67560 gctacggcat ctgtagagtt ccggcgactt cgttgaacat gtgtcttgcg aattgtcacg 67620 gcaagccgca atcgccggcc tgccgagtgg taccccagga agactgcaag aaactattcc 67680 attggtcaaa ccagacagtt ggtgcccagg atcccaagtt cgccacgaat gaccccatgg 67740 tcacatcggt gaaattgatt atgtaagcga tgcagatcgc cgccgatagg gccaagcctc 67800 tcggtcaggt catcgtgacc aacctggttg aggccgatat cgagggccac aagctctcca 67860 aagacgagtt tggctccttt cagtcattat gctgacggcg gccggtaaag agaacaccag 67920 aaattgcatc atgcagagca tgatgcaatt taccaacttc cctgattagt gggagctgta 67980 caagcaagaa agcccccggc accacggccg acaagatcat ccgacaggcc accctggtca 68040 tgtctttcca gcgaacggtg ctaaagtagt acgagttatc cagcgtatcg atcaagaagg 68100 gccagcgagt ggttgtgatt taccgctcag ccaacttcga tgagaaagtg ttgacgatcc 68160 gtttgccttg tagcatcatg cgtaatccca cccccacgcg ggatttaatg acaccaacgt 68220 gcattactgc atcgggatca acctagcacg tatgaccatt gaccggatgt tccatgcgat 68280 cgccgagtcc atgccgaatc tgtaatcgac cggcaaaccc aagtagctgc ggtcgggctg 68340 gctcaatggg gtcaagcatt ggcaagtcga ctaaaccata gccaagatta aactataata 68400 ccctgtagcc cattaggaca tagacttaaa caggcgagtt gatggctaac tctaaggctg 68460 tccacataca gactgctagc gcgcccttgc ggttggcctg atgtcgaaat gctgtcaccg 68520 ggtcgagacg aagttcagct aactgtctcg gtgtgtagca tctgtgtccg ttaaccaccg 68580 ggaacgaaat cgctttaacc atagaagaat tcgacgatgt ggtagaagat ttcacggttg 68640 gcgaccacgt cactgtcgac tggctcggag gacactgcaa ccactgcccc ccctaccgca 68700 aagacatttg catctgctat gcgaacataa agatacctag ctggcatgaa cccggcggat 68760 atgcggagtc ggtgacagta cccgccaatg cgctggctcg gatcccgacc aaacgatcct 68820 ttgtcgaagc cactccgatg ggctactccg gccttcacca cttgctacgc gctgcgcaag 68880 accaaagcat tgaccggttg gccgggttat aatacttaac gttggtgtac tcgaccatct 68940 tggtgtgcag tttgcccggg caatgggctc gagaccattg cggtcgctcg cgacgctgac 69000 aaagctgtgg aggctaggaa actgggcacg cataaactac atcgactcca ccattacgac 69060 gtcgccgaag ccatgcgcac cttggcgaag cagcggtaat tctgaacgtt gggcactgcc 69120 ggtaattcca tggcaataac agacacaatc ggcgacttac taccccaaga cgaactcgtc 69180 gccatcgatg tcacaatgta cccgctgccg atcagtcccg tgtagctgat catgccggag 69240 ctcagcgtta ccggccatcc ctcctgaacg gcgcgcgatg tcaaagcggc catgaatttc 69300 gccgtcgtgt cgggcatgga attaaagttt cgtgcgatac caaacacagt ccggtctgtg 69360 acccacagag ttaacggtgt aatgtaaatt atggacgcat ccgacggtga ttgctagttt 69420 ggacctgcgt caccggaaaa gttgcgcagc tgggtcatag tctcaccatt gcgatgacgc 69480 gctggcgggt cacggtagac tggaccagtg ccaaaccggt agccgcggaa cttacggtcg 69540 aaacgaattc gttcgagatg ctgcacagcg cagggtgggg tcaaaaggct gtctgggccg 69600 gcaaaagctc cggttcgggc aaaccgctga ggtcactgaa cgccggccgc tttccccaga 69660 tccgctttgt tgctgaccac tagcgacaag attgtcaaga tcggcaacag ctaccgtctc 69720 accgggagac tgtatgtgcg ggagaaatag cgggagcacg taaccgattt gcgcacagaa 69780 gagctcggca actcataacg aatgttctcc cagtccacgg ttcgccaatc cgaccatagc 69840 atcaagcccg attcgttatt aatgagctca atacagatag ctgaggaatt gacggtatgc 69900 tttgccgccg ttcgagtctg tactcagact tacaggtttt tgtcgggtcg tctgtcgctt 69960 gatcgcggta aactaccggg gatgtgctta agaactctcg ttatgtacgg tggctgacca 70020 tttggatcca gttcgggatc acacagtaac gcgctttgct gttccagcag cgcagtgggt 70080 tctgttcccg attcaacggt tctgttcccg attcaacgga ggcgaggctg atcaacggct 70140 gcacctatga cacggattga tgtgctggac gccaccgcct ggcgaacgct ggtatggcag 70200 acacagcagc ttctgcaatc tgtggcagcg acttaacgca tcgcgcgtgc ttaggtgcag 70260 tggaattcgc acccgaagcc agctggcaag cccactgcta gtgtacagca aagttacgta 70320 aaataaccgc ggcggcggcc aaagcggtaa cagccccggc gtaagacaac cgctgaggcc 70380 gtgccggcat ggtgggttag ctggtggatg ccaccagccg ctcgtcggtg aactcgatgc 70440 tctgaaccgc cgccagagcg gcacctcgtg cgatcgtaac ctgcgccatg gtccgcggaa 70500 aaaccggcac cagcaaagct ttttcgagtt gccatgacaa tccatcaaag ccgatatgtg 70560 cgcctacacg ttcgacgcaa atgggcccac atcgaacaag aatccgctgg taggaacggc 70620 ttccgtgcgt cgaccaaacg gttgcggtat ccgtgacggg taaccgatac agaactgaga 70680 tcgcttcgcg tctcgatcga catctgggct attcgcaggg taaattctgc cgagagcacc 70740 gacaacatac gataaggggt attaggttta tgattgacgt gagcgggaag atccgagcct 70800 gggggcgctg gcttttggtg ggtgcagctg cgactctgcc gagcctaatc agccttgctg 70860 gcggagcggc gaccgcaagc gcgttctcac gaccaggcct acccgtcgag tacctacagg 70920 tgccgtcgga ggcgatgggg cgcagcatca aggtgcagtt tcaaaacggc ggaaacggct 70980 ctccggcggt gtatctgctg gatggtttgc gtgcgcagga cgactataac ggctgggaca 71040 tcaacacctc cgcattcgag tggtactatc agtcgggact ctcggtcgtg atgccggtcg 71100 gtgggcaatc cagcttctac agcgactggt acagcccagc gtgcggcaag gcaggttgca 71160 cgacctacaa gtgggaaaca ttccttacta gcgagctgcc taaatggcta tccgccaata 71220 ggagtgtcaa atccaccggc agcgccgtgg tcggcctctc gatggccggt tcctcggccc 71280 taatactggc agcttatcac cccgatcagt tcatctatgc tggctcgttg tcggcgctga 71340 tggactcctc ccaggggata gaaccccagc taatcggctt ggcgatgggt gatgctggtg 71400 gctacaaggc cgcggacatg tggggaccac caaatgaccc ggcctggcaa cgaaacgacc 71460 ccattctgca ggctgggaag ctggtcgcca acaacaccca cctatgggtt tactgtggta 71520 acggcacacc gtcagagttg ggtggaacca acgtacccgc ggaattcctg gagaacttcg 71580 tgcacggcag caacctaaag ttccaggacg cctacaacgg tgctggtggc cacaacgctg 71640 tgttcaacct caatgccgac ggaacgcaca gctgggagta ctggggagcc cagctcaacg 71700 ccatgaagcc cgacctacag aacaccttga tggctgtacc ccgcagcggt tagcctggcc 71760 ctgtctgttg gtccttgcac cgatcgcccg cccaactagt cgcccggaat ttacccgtga 71820 tatcaatcca tccggttgtg ttgttggcat ggcgctggtt gttcatgctc cgacactgga 71880 ctgtagagac gtaccactca cacgttcgga tcattgctcg cgtttgccgt taatgtcggc 71940 gcgactgcag tgtctacata tccgtatgtc agtcaagcta gctctcctac aacggatcct 72000 gcacggtccc gggtcacgct caacagagtt tggccatccg ggccagaatc acaatcacaa 72060 ggagccaacg atactgatgg gcagcactag taatcgcatt taccgagatc gacgctgcgc 72120 cgtttgggcc acttcgcccg aagtgcttgg gcacgctggc cgtgctagtc gtaacgctga 72180 ttgccaactc accgcaggcg agcaccggtg gcggtaacct gctgatcgaa ttgaccgacg 72240 gcgccgcaca gcggttggtg gtcgccgagc cggccggcca ccttgaaatg gatcaagcac 72300 ggcgacattg aagatccaag ccacgtccag caagtactcg ccaaaatgcg cggcgaagac 72360 gtgactgcca gcgatccgga gtacattgca cggaccttcg gtgaccagat caacgctacc 72420 aaggccgtcg aatacagccg gtgatggatt gagaagttca atccatccag tgcgccaacc 72480 acgtcaccgg agccttcaac gtcgcgatcg ttgatcgatg ttttcaacga aacgaatacc 72540 gacccagata gcgctcaact ggtacttgct gtattcgcca gcatgcgtca tccaactcga 72600 tgccgctcga aacgacgtca tccggaatag ccaactcgcc ggcctctatc agcaaaccct 72660 ctcgttggcg actcagtcgc attgttaggg ctccccgctg acctgatgca cgggccacct 72720 ctcgttgagc tgcttacggt gccgatcccg gttcgatata taagctatct cacaagcttt 72780 gcaaaggggt aacgttttgg acatgccggg agaaatgctg gacgtgagaa aactttgtaa 72840 gctgttcgtg aagtccgccg tggtcagcgg gatagttacg gcgtcgatgg cactatccac 72900 atccactggt atggcgaacg ccgttcctag ggaacctaac tgggatgcgg tcgcgcagtg 72960 cgagtccggc agaaactggc gagctaacac cggaaacggc ttttacggtg gactgcaatt 73020 taagccaacc atctgggccc gatacggcgg tgtcggcaat cctgccggcg cgtccagaga 73080 gcaacaaatc acggtggcca accgagtttt agctgatcaa gggctagacg catggccgaa 73140 atgcggtgcc gcctctgacc tgccgatcac gctgtggtcg catcccgcac agggcgtgaa 73200 gcagatcatc aacgacatca tccaaatggg cgataccaca ctagcggcga tcgctctcaa 73260 cggcctatga acgaacagaa aactgtgttt agatcaagcc atggaaggtt cggtgaccgt 73320 tcatatggcg gcacccgcgg acaaggtctg gaatctaatc gcggacgtcc gcaacaccgg 73380 acggttctct ccggagactt ttgaggccga gtggctggac gatgtgactg gcccagccct 73440 caacgccaaa ttccgtggtc atgttcgacg aaatgaaatc ggacccgtgt attggacaac 73500 atgcaaggtg accgcgtgcg aacccggccg tgagttcggc ttcacggtcc tgttgggcaa 73560 caaaccggta aacaattggc actaccgatt ggtgacgtct ggcgatggca catacgtgac 73620 cgagtcattt cggttcaacc gttcgccact gctcaccgtg tattggttgc ttggcggttt 73680 tctgcggaag cgccgcaaca tccgtgatat gaccaagacg ctgcggcgca tcaaagacgt 73740 ggtcgaggcg gagtgacggt ccgtccgaca gcaagtagcg tccgctggat cgaccagctc 73800 gaggctctag cccggaattg gtgcataacc gtattgccac gtccgtacct acgcttatgc 73860 caaatgccaa aaaggccgta atgtgtcgga attgagacga gctggtgcag aactaatagt 73920 ccagagtagt cgaggtactt gtggttatca tcgccctcgc cttggcgtgc gcggaatccc 73980 cctcccccga cgagctacac aactgaccat cgacgacaac gttcattcga cgcattccgt 74040 tgcatgcagc taaagccatc ctagcggacg atcaatatcc gcgaaagcag cagccaagtc 74100 aaagccgtag agcttgttca gtgccggcaa ggcaacttcc tcaataggtc aagatccgca 74160 acgtcgacgg attcactggc agcttctggg cagacggagt gggagacgca aacgccgagg 74220 gttgccaaac acgtacatta tcacccgcta gtgcctccga catcaacagc agtgatctca 74280 acaaagtcgt aaccacagag ttcaagatca cctgctgtag cgctgagccc gccacattct 74340 tgctgctgcc accctgactg gggctgtcag ggtgggccaa ttggcgcgcc aacaaagcgg 74400 caccggccac actcaaagcc gctttgagaa cgacgattcc gtttgtcgac tcatcccaca 74460 ctcacagcag gttcggcttc cgtaggcaag attgacttca acaaacgcaa ccttagcggc 74520 ttgatcctta taactcaaaa accggcctag ttgcgcgaat gcctaaaaaa gcacctcagc 74580 tcgtttgggg cgtacccgag cccggagccc cgtcaggtct tcaacggcaa tactgcgcct 74640 ggtgggttga gcctcggcca cgatacgttg ggcaatctgg tggttgacaa tcggcagcga 74700 accactgctt acttgcgacg acgtttgttt aacagtaacc acgccggcgg agaggtagaa 74760 ccacccagac aaaaactcaa gagcggccag ctaacgcggg ccgagcagac gggatcggct 74820 tcttcccgac cgcaaatggt cgggattcca ctgaagaaag ctggtgaatt agcatctgta 74880 gtccggccga ctgatggagg atctgtacgg cagcgtttgc actggttcgc acaatatgga 74940 ttcatccgcg gtatcgcggc aactcaccac ccggcgaagt gacccgttgg cccgcttgga 75000 tatcgctctg gccatcaagg cgaatcccgt gcccttactg ccacaaaccg cgtccccgac 75060 gcccgttagt gcagagccgc atcagctatt tgaccgccaa ccgtgcaatc acacatgaac 75120 tgctgcaatc agaggacttc cacgtgttct ggcttaacgt aaccttgccg gcgccgtcgc 75180 actggctata gaaccagcag ccaatacaat ttgttgcatc cgttgctggc tattcaatga 75240 gcctatcaca tccactaccg caagacggta tcgccgctgt tcgcgcccaa ggcagtcgcc 75300 acgttacggg atcggatcga gcagaccaca ttagccctat tggatcaact cgcccaccaa 75360 catgacgtcg ttgacgtggt caaccggtat tgttcgcagc ttccggtcgc ggtgatcagc 75420 gatattttag ggtacccgat cgcgaccgaa gccacattct taagttcggc gaactggtcg 75480 cacccagctt ggacgttgaa ctgacatagc aatagtacca gcaggcataa cgagaggtag 75540 cgggtttcaa cttttggctc tcaaacactt accgcagttg caacgtaccc caggcgataa 75600 tctggtacgt cacctgagtc actaggaaga caacaaacct accgaaatat ctctcagcaa 75660 aagcaaactt caggcaatct ccggggctgg tgttggctac cgggggtgaa accacggtga 75720 acctgctagg caggggtatt attcgtaata ttattgctgg atacacctga gcatatggtg 75780 atgctacagg cgtgccccga gccggggcac aaacgcggtt aagagatcct gcggctcgat 75840 tcgccgattc agatggccgc tcgggtagcg cgcaaggacg tcgacctagc aggtagcacg 75900 atcaagcgca gccaggtagt ggtgctttat tttggccgca gccaaccagg acccgtccgt 75960 ctttgccgat ccagataggt tcaacatcga acgcctcaat gcgggaagga atctcgcatt 76020 ttccggtgac aggaattttg tttggaaaat gctcttaccc gcgcctacaa tgcagtgggg 76080 ctgcgagcct tcttcgacca cttaccgtag acgcgggcag ctggtaccag aagtaggctg 76140 gacacgcggg tgctgagagg ttggtcgaca ctgccgatag cgttgggacc gacacggtcg 76200 atggtatctt aagtgatcga cgaattctgt gagtctcatg gtgtcgcgcc tggtgaacag 76260 gccagcggcg ccttttgaca tcggtacaac aaccgaatgt tattggccac tatgcgagac 76320 gactcctagg tcgccgtccg agatgtccta ctcgagcttt gacaggcact ttggcgtcgc 76380 gactaggagg cagtaaaacg ttcttaccgg ccgactgtat ctatgccgac cttccggttg 76440 gtccaacttt ggcagctcgg ggcctaacga tatcgtgaag cggctccagt tcggaactcg 76500 aatctgctta gctgagaata ccaaaatcac gacagcccgc tggtgtgcaa cggcgccgac 76560 gccatgtctc ggttcacctg gtagccgaaa acagcagtgc gcaggtcgca ctgtggaagg 76620 actatttggg acacggccag catggccgct caaagcaccg tggacctact tagcggagct 76680 cgccgcagcc gacacgtctt gggtgctcaa cgtgacaggt ctgaatctaa gtcggctgtc 76740 atttaaaaac caaagcagcg gaaacgccag cgacgattca ctcaactagt agaagctagc 76800 attctcgaat tgaagatgtt acgcacggga tactttaaga aagtaaagca caaagtctac 76860 aaaagaggca actcatgacc aatcagaccg accatggctt tcgaggctct cactatagag 76920 agtccgagcg ggaaatagtt ccgttgggat atcggtagtt cgcagccggt agtgcaacag 76980 ctggtggcct tcggcggtca agcaggctag gcataaagct gacagagtca gggtcaattt 77040 tcagataggc ttacactaca aaactagaca acaggcttga gagttaattt gacgcgttgg 77100 ccgagaatgt attctaccac gtgttcctcg acgaggaaga gacccattac gtgcatgccc 77160 tgcaccttgc cgctcggcca gcggcgcgcc tatataatat ccaaattcgg atggcacaat 77220 gttaacgacg tacagtggga agggttgcca tccaacagct tcgaacggag gttcaccgct 77280 ggagagcggc ttctgaacta cctggagacc tcgacctagt gtggctcgtt tcggtactga 77340 cgccctggca catatagaga acatgggttc caatccggct tggaagaagc tgctgcagga 77400 tcaactaggc cgttattggg ctcctgccga atgacttcca ggtgcacatg ccgatctgtg 77460 cggtcccagc gaccctcgtc gattgactta ggcagcgatg gccgcgggcc gtctaccagt 77520 gcatgcgtac agcgcatctc ggtgacgtac aagccgccct cgaggatcac atcacgcacc 77580 taacttggtc gcgctaacag cgttcaaatc tatcagacac actagttgcg agctctacgc 77640 acaggagcac tcaccattgc acactcggca actaggggca gcttgaccga tcaggcgcat 77700 agaccgcaga tttggcgtag ctgcccgatc ataacaaaag caggacgctc acgagcagta 77760 ggatggcttc atcaccgcac ctggcctcga tcgtggtcac gctgaccgcc ttcttagtga 77820 acagcaaagt tttttcctct actgtaggag atcggcagat cttcagctcg ggtgattcca 77880 ccgggagcgc tgtgtctata tctcggcatc ttgcttagtc tggcacatct aagtgcgcga 77940 agagcattgc tgatcaaggg cttctgacta tgtgccgctt gccgtgctct agactggaca 78000 tcccacgaca cgccaggact ccgctatttg atgtaccgac taccccaaga atgcagacta 78060 tcgtaatagc cgcaggtgca acgtttgacg aagtgttcgc cgcggtggcg gcccacgtgg 78120 tgctattcta tggctatagg gatctatggc tatagggagc cttgcgcgtg cagccatggc 78180 cggcgacctc caaatccagc cggtccgagc aagcagcaat gctgatcctc atccttgatg 78240 aggatcagca ggaactccac aaagcgtggg aagcaccaac ctacaatcga tgaggttcaa 78300 ccgaagtcgg gttacatgca gtcggatgcg gacgcggtca aggactgcga ctggacagct 78360 gcgagtgcga agtcgtcctt gatcgtgtcg acaacaattg ccgacgggtt ggctccgacg 78420 aaccagtagc ccgcacaccc gctaccagac taagtaacca gaacttctcg tttatccgct 78480 acaaccttgg caatcgagtt atatcgtcga ccggccagtg caacttatgc tagcggttta 78540 gcacggattt ccgatatcgg taggctccgc aaatcagact tctgctacgg gataacgacg 78600 gtgccggaga tggtgtttcg tcacgcttta gacactggtc tcgtatgtca gatatagcat 78660 gccaatcatg ccgccgtcgg aaccggcatt atcgtagtat aggtgaaccg gatccggacg 78720 tgttgtcttc atcgctgatt gccacgccgc tacggtggga gttgtcgtaa cagacgatcc 78780 agattcaatt ggccgacagt ccgcaacacc atcagatcgg tagcaagctg cgtcggttca 78840 tctcttttca gtcgatcttt ttgtcaaggc ggtagaagtg ggcgattgcc atgagcaaca 78900 gccggcaacg cctcaatggt gttggccccg ctccagtcac cgtcctaggc aaatacacgc 78960 agtaagtggt gcatgccggt gcgccacagc gctgtaccca gaaagtagag ttccgcggga 79020 ccgaacccgt acgacgggta caggatcctg caaaaagacg ccatctcaat cacccaggcg 79080 ataaatgttg gtggccgagc ctctaggtaa ttcattctca actcaccgtc gagatagaaa 79140 ttgttaaaat ccttttccag atagcaagat tcacattgat agaagtagca atacagaaaa 79200 attattgagt ttcccagact gtcgaagaaa gtcaagaata tacagtggat tgctcttgta 79260 taaaccacag tctcggtctt cgaaaccgaa atggaattga agcagcttgc caagtcgcaa 79320 cgcttgctgt agcacaaaac gcagcagcct cctatacgca tagacaaaca ctaccggtat 79380 agcgcaccac gcggcttgcg ttctcaacag cttgtgatac ttatggctcg gtcaagtggc 79440 cgtcacacct ggcccagtag gccaggatag acttggaaac taccgaggta gctcagctcc 79500 ggatgcaaaa tccccctccc gaacaccgat gcgtaggcac cggacatcta cgcggcctgc 79560 tcggctacct actcaagaca aatcacctag tgcacagaac ctccaaacag tgcgttcaga 79620 tcaaaagcat cggctatacc ctcgccgatt ccggtgtcga tcagtcagtc attcactcta 79680 gcggttggca aaacagccga gtcaattcga cttcgctgaa ctggcagtgt agatccaata 79740 caacctggag atcaatgtgt ttaaccagat ctaggatggg gctgcagggg gtgcaaacaa 79800 cgaaaccgat ccatgaattg gacgtagagt cgaactttgc aagcggttcg gtgggttcgg 79860 tgttagtctc gttgaaagca ttttcgaatc gtctttagtc cctgcgggaa attagcagcc 79920 ttagacacac tgatcaatga acaccacttc gccgacatgt tgcgctaaga ccaatacatc 79980 aaacaccacg acaagttccc agaccataca gccagaatga tacgccagct gctcgggact 80040 caggagcatg tagcgctcct gccctataag acgaacgcaa ccaccatgtc tattgcagga 80100 tcgccgatgc atatctcgca ttaactgcga attatcaagt gcagcaatca cttaatcccg 80160 aaactcgaga agaccgtact acaaccaccc tgctgacggc agccggccac cgcctggatc 80220 tactagcagg aattcgattt ctcgaccaat caccgcgtcg attcctgctg caacaagcag 80280 cagcctcaac ccggctcaac gtcacgcggc tgcacgcgga aatagttacg tcgtcctact 80340 cgaaaaacgc ggcgggcgcc cccagacaaa cctgtcgccg atgatgcgta gtgcggatag 80400 gtctatggcg gtggcgacac ttctgtattc agtggggcga caagctctgc agcagcgagc 80460 gagttaacct gtcatagcgg ccattctgca gcaccaactg gctgcagcac caactggcca 80520 ctccatgctg acgacaggta gtgcgggtca caccaccctg gctgggcaag gtcagcttgc 80580 aggactgcct taatatccct tatatccaga gtccgcagaa cccgccccgg gccgatacac 80640 agcgtgtacg atatagtcat agtcaggaca acgaacaact cgtcggagaa gtacttgtgg 80700 cgaactggtg ggcggcctcg gcggtcaacc cctcccgtcc actgtaaccg gaccaggtaa 80760 gccactccat cacgcggccg tacaactctt catcatcaac cccttcggca gcactttctg 80820 catcgtgcag tgtttacgca aacgacgcat tcgtcgtcgt gggcgatcac cgctcgtgcc 80880 agttcgcgtg cgtgtcaaca gccagtgctt ggtgtagact gcctctagac tgaacccggg 80940 caacgcggcc aagatcgggc aaatgcagaa tccaacccgt caaatcgtca tccgcaaatg 81000 taccgattcg gctcatggcg tgatattacc ccgcacattt ccgcagaatc gttttgcgac 81060 tgctgcctgt gagcacccga gagccatagt caacgaatca tcgtgccaac cacgttggac 81120 cataacccga tgcacgaagc gttgcagggc agcttcgacc tcacggtagc ccggccgacc 81180 ctggtagctg atcgaggcgg accagcttgt cgacaatcca ggccagcagc agcgagcaca 81240 cgtagttcaa tggtcacatc cctagctggg ggaagccaca attagtcggc gtcgtacagc 81300 ggctagccag agtggtccga caaccacata acagcacgac cgtcaccgca gcccgatcag 81360 cgcgctaccg aacgcaggat gcacggtggg tgagcctcga ctaggtccgc ggtccgctgc 81420 tcgcgggtac gttatactta ccagtggact agcgaggtta gcctcgggct ggttaactcg 81480 gcggccggga gacgcattgc gccgagtaca actcctcccc tagctgcccc ataagcgcta 81540 gttgcgtttc caagtagtcg atgtgttctt cctcgtcagc cacgattttc tccaacagta 81600 cagcgctggt gctgtcctgc ttttcccggc acatgatgat tccgggcttg agccgactca 81660 tcacctcgta ttcgatcgcc aggtctgcct cgaattgctc acgcagcgtc tgaccaacgc 81720 gcaacgaccc tatgcgctgg taattcggca agccgtccag aagcaagatg cgatcggtaa 81780 tcgcctcggc gtgccgcatt tcgtcgaagg actccacgcg ggtgcgctct gctaactcgg 81840 taaagcccca gttttcttgc atctttgaat gcaggaaata ctggttgata gcggtgagct 81900 cactggtcag ttgctcgtta agcaagcgca agacatccgg atcaccttgc atgaacactc 81960 ctataacgtg ggtaagagat catgtcgaac cgctaaaggt ggaccgaagc acacctcggc 82020 tttagtttat cctcacaaat aacaatacac tatggtaaca atacactata gccgggcctg 82080 ggtcagatct agtacagcag gtacgggtca gtgtgggatt ttagtgcact gtcggcgcat 82140 cacgtgcaag ccaccatatc aatcgcaggt cactacgtta aattttagac gagactgcac 82200 taaaaaccta cttaggccta cttaggttag actccactaa tatgcgacct gtttgcccga 82260 cggcatcgcc tgggtttcta atcaagcgag atacgatgag cgcgcatcta gtgaggcatg 82320 tcacctgcgg tcgggaactt tgctgatgta cgtctgtctg tgtgccggtg ccaccaacca 82380 aactgtgtgc gatgtcgtcg cacgtggtgc gacgacgtcc aaggagatag cagccgcttg 82440 cggagcgggc agtgactgcg gacgctgccg acgcacattg cgggcgatca tcgccgcctc 82500 aaacccgact gtgaagcctg acttaacccg accagctaaa caatatgtca aattgcgtgg 82560 cggtcggtga agtccactca agctacggcg gtggcctgaa cgcccataca gatcagcgaa 82620 gtgaggactt cctcgcacgg gtcgctgcgg cgatctcagc acagatcggt tcgatcctcg 82680 tggtgcttga ctgccatcca acttgaaatt ggcctggagg caaggattcg gcatgtcggc 82740 aggcttcaga cagcagaact tccgggtcgc acacccgcca gaccagcccc atgggcaacg 82800 cttcgtaggc gtgaatccat ctcccgaggg catcaacagc caggcagccc gccgaccccg 82860 tcactaggtc tctcgctgtg atgtttaacc gttgccgtgc atccgcgttc gcgcgatcaa 82920 caccacacag cacaccgttc ctttggccat cattcggtcg tactcttgcc agctgtcatt 82980 gctgccgctc gtagcggtaa aaaccttatt accttgaact taaattttta gagtacaaag 83040 ctgtaattag tcggcatcgg ccagtcacgg ctgtgtctca tccgacccgc tccgtgcagt 83100 catcgacagt cccccactgc cattcgctgg ggaaggttat gaccagctac gaccgggcct 83160 gcagattggc gattttcact ttcctccagg cggtagaacc tataaaaaga ggattcgcca 83220 ctggcggggt ttggcaacag gacgacatta actaacgaag tctgcaccgt ttcgccagag 83280 tgaaccgtgg agaccaccgc tagatcgttt tctatcgctg cgaacgccac agtattagtt 83340 aaatgttgtt tagtatcctc ctaggaggtc ctcgctcatc tgaaacggtg acttgaacat 83400 gtagcagcta gttggaacaa cgtcaatatt tttgttcacg ccaaatgcag ttgtgctaag 83460 taattgctca gcttagccca tgttgcagat cgttgtcgta ggtgtcctcg aagaaagcct 83520 tcagaccgat gatcgcctcc gctaggaaca actctttgac ggtacccgtg cttcccggcg 83580 agtgtgaagt gagagtacgt acgaccccag cctggatgta cccaaatgtc agctatatct 83640 caatgatcac ctacgtgtgg ccacgttgcc aacgacccag tcaagtcccc ctgttctagg 83700 ggaatgaact ggcatggcag aacaatgttt cctaaacacg ttgtacgaat acatgattca 83760 gtaacaatcg gcgtcagtgg gatcgattct gtcatcaaat acacgccgag ttgatcgcac 83820 tcctaagcca gccacttaag tgctatcgcc gtctgatcag cagagcattg ctgagtccac 83880 agagtcacca ccagcagcaa cgttgtaaac gtcatgaatt tgagtggcga accgcgctat 83940 tatgtggacg tcgatcaaga acccgggaaa ccgaacccaa cagcgcatcg gcgaccgcgc 84000 ccccctggga gcgtaccaac catcatcgga ctcagcacgc ataagcaggg cgattatctt 84060 ttcctactag ggcgagctta ccgtcgctgg catgggcatg aggacgatct ctggtttgcc 84120 ggtacccgaa ctgctatgcg accagccgca catgatgctc tgtactaatc aactcaccaa 84180 tgatcttggc aatctgccga taggaagcac tgcgaccgct agcggagcgg aaagccagac 84240 caatccgtct cccggggcag ggggcagcga actgggcaag tccaagtttg ctacgcaccg 84300 actcgacagg cgcagcactc tgcgggagca gcgtcacccc caacccgccg gtcacgcatt 84360 gcacagcggt cgccaacgac gctgcgcggg tgttagccag ctcggcctgc actcccgatt 84420 tccggcagat atcgagggtc tggtctcgca agcaatgacc ctcatccaac aacaacagcg 84480 gcaattgcgc cagtgccgtt gtcggcaccc ggcgcttgcc ggaaagcgga tgccctgggg 84540 gtagcgcgag gacaaaatcc tcatcataga ttggtatctc ggcaatcccg gcagtttcaa 84600 ccggtaaggc gatcattgca gcatctaatg ccccctcacg caacgcggtc agcaggtgct 84660 ctgtctggtc ctcgaccact cgcaaggtta acgtcggcag ccgatgggtg agtccagtca 84720 acatcgtcgg cagcacatac ggcgccacgg tgggaatcag tccaaggcgc atgccacctc 84780 gcagcggatc cgattcgccg gcagctgctg cggtgaacgc gtccatcgcc tcgatcgcag 84840 cctgggcgcg tggtagtagg tgcctaccct gcgtcgtcac gaaaacccgt cgggtagaac 84900 gttcgatcag ctgcacacca agtccggact ccagcgccgc taacgcctgc gacaacgtcg 84960 actgcctcac gccgagaaag cttgccgcgg cgctgaagtg acccttctca accactgcga 85020 caaaggcgcg aagcccagcg atggtgggct gataactctt atcactcata ccgataagta 85080 tagtgtgata tatcaccttt acttcagacc aaactcacgg caaccttgaa ggatagtgta 85140 aaaatctgat tttgaatcaa tccaaacaag gatcggatat gtcattgcta tcaattggcc 85200 aacagttccc cgcctaccaa ctcaccgcgc tgatcggcgg cgacttatca aaggttgacg 85260 cacagcagcc tggtgactac ttcaccaccg tctccagtga cagccaccca ggcaagtggc 85320 gcgtagtgtt cttctggccg aaggacttca ccttcatttg tccgaccgaa atcgcggcgt |