 |
|
EBI DbfetchID AL583923; SV 1; linear; genomic DNA; STD; PRO; 348950 BP. XX AC AL583923; XX DT 20-FEB-2001 (Rel. 66, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 3) XX DE Mycobacterium leprae strain TN complete genome; segment 7/10 XX KW . XX OS Mycobacterium leprae OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Corynebacterineae; Mycobacteriaceae; Mycobacterium. XX RN [1] RP 1-348950 RX DOI; 10.1038/35059006 RX PUBMED; 11234002. RA Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R., RA Wheeler P.R., Honore N., Ganier T., Churcher C., Harris D., Mungall K., RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K., RA Duthoy S., Feltwell T., Fraser A., Hamlin N., Holroyd S., Hornsby T., RA Jagels K., Lacroix C., Maclean J., Moule S., Murphy L., Oliver, Quail M.A., RA Rajandream M-A., Rutherford K.M., Rutter S., Seeger K., Simon S., RA Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Taylor K., RA Whitehead S., Woodward J.R., Barrell B.G.; RT "Massive gene decay in the leprosy bacillus"; RL Nature 409(6823):1007-1011(2001). XX RN [2] RP 1-348950 RA Parkhill J.; RT ; RL Submitted (20-FEB-2001) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Mycobacterium leprae sequencing teams, The RL Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, RL UK Unitie de Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du RL Docteur Rouux, 75724, Paris Cedex, France. E-mail: parkhill@sanger.ac.uk XX DR EMBL-CON; AL450380. DR GOA; P68998. DR InterPro; IPR001383; Ribosomal_L28. DR RFAM; RF00174; Cobalamin. DR UniProtKB/Swiss-Prot; P68998; RL28_MYCLE. XX CC Notes: CC CC Details of M. leprae sequencing at the Sanger Centre CC are available from http://www.sanger.ac.uk/Projects/M_leprae/ CC A relational datbase containing the M. leprae sequences is available from CC http://genolist.pasteur.fr/Leproma/ XX FH Key Location/Qualifiers FH FT source 1..348950 FT /organism="Mycobacterium leprae" FT /strain="TN" FT /mol_type="genomic DNA" FT /db_xref="taxon:1769" FT repeat_region 95..794 FT /note="Dispersed repeat, RLEP, copy 27" FT CDS complement(1041..1889) FT /transl_table=11 FT /gene="fpg" FT /gene_synonym="ML1658" FT /product="formamidopyrimidine-DNA glycosylase" FT /note="Highly similar to many formamidopyrimidine-DNA FT glycosylases (EC 3.2.2.23) thought to be involved in DNA FT repair after exposure to alkylating agents e.g. Escherichia FT coli SW:FPG_ECOLI (P05523) (215 aa); BlastP Expect 8.7 and FT Mycobacterium tuberculosis SW:FPG_MYCTU (Q10959) (289 aa); FT Fasta score E(): 0, 80.6% identity in 289 aa overlap. FT Contains Pfam match to entry PF01149 Fapy_DNA_glyco, FT Formamidopyrimidine-DNA glycosylase." FT /db_xref="GOA:O69470" FT /db_xref="HSSP:1K82" FT /db_xref="InterPro:IPR012319" FT /db_xref="UniProtKB/Swiss-Prot:O69470" FT /protein_id="CAC30611.1" FT /translation="MPELPEVEVVRRGLQDYIVGKTITAVRVHHPRAVRRHVAGPTDLT FT NRLLGTRINGIDRRGKYLWFLLDTDIALVVHLGMSGQMLLGTVPRVDHVRISALFDDGT FT VLNFTDQRTLGGWLLADLMTVDGSVLPVPVAHLARDPFDPRFDVEAVVKVLRCKHSELK FT RQLLDQQTVSGIGNIYADEALWRAEVHGARIAATLTRRQLAAVLDAAADVMRDSLAKGG FT TSFDSLYVNVNGESGYFDRSLDAYGREGEGCRRCGAVMHREKFMNRSSFYCPRCQPRPR FT R" FT misc_feature complement(1059..1889) FT /note="Pfam match to entry PF01149 Fapy_DNA_glyco, FT Formamidopyrimidine-DNA glycosylase, score 531.10, E-value FT 7.8e-156" FT CDS complement(1944..2660) FT /transl_table=11 FT /gene="rnc" FT /gene_synonym="ML1659" FT /product="RNAse III" FT /note="Highly similar to many ribonucleases involved in the FT digestion of double stranded RNA e.g. Escherichia coli FT SW:RNC_ECOLI (P05797) (226 aa); Fasta score E(): 1e-24, FT 41.8% identity in 213 aa overlap and Mycobacterium FT tuberculosis RV2925C SW:RNC_MYCTU (Q10962) (240 aa); Fasta FT score E(): 0, 86.8% identity in 235 aa overlap. Contains FT Pfam match to entry PF00035 dsrm, Double-stranded RNA FT binding motif. Contains Pfam match to entry PF00636 FT Ribonuclease_3, RNase3 domain.. Contains PS00517 FT Ribonuclease III family signature." FT /db_xref="GOA:O69469" FT /db_xref="HSSP:1DI2" FT /db_xref="InterPro:IPR011907" FT /db_xref="UniProtKB/Swiss-Prot:O69469" FT /protein_id="CAC30612.1" FT /translation="MTQPRQALLDAFGVDLPDELLSLALTHRSYAYEHGGLPTNERLEF FT LGDAVLSLTITDELFHRHPDRSEGDLAKLRASVVNTQALAYVARNLSDGGLGVYLLLGR FT GETNTGGADKSSILADGMESLLGAIYLHHGIEVARQVILRLFGTLLDAAPTLGAGLDWK FT TSLQELTAARGMGVPSYVVTSTGPDHDKEFTAVVVVMDTEYGSGIGHSKKEAEQKAASA FT AWKALDVLGGVGKTSV" FT misc_feature complement(1980..2177) FT /note="Pfam match to entry PF00035 dsrm, Double-stranded FT RNA binding motif, score 84.20, E-value 2.7e-21" FT misc_feature complement(2259..2540) FT /note="Pfam match to entry PF00636 Ribonuclease_3, RNase3 FT domain., score 155.60, E-value 8.2e-43" FT misc_feature complement(2514..2540) FT /note="PS00517 Ribonuclease III family signature" FT CDS complement(2657..3310) FT /transl_table=11 FT /gene="ML1660" FT /product="conserved hypothetical protein" FT /note="Similar to several proteins of undefined function FT e.g. Mycobacterium tuberculosis RV2926C TR:YT26_MYCTU." FT /db_xref="InterPro:IPR003772" FT /db_xref="UniProtKB/Swiss-Prot:O69468" FT /protein_id="CAC30613.1" FT /translation="MTVALALRDGCRRISTMTRQYGVTTQRHLISPVVFDITPLGRRPG FT AIIALQKTVPSLARIGLELVVIEWGAPINLDLRVESVSEDVLVAGTVTAPTVSECVRCL FT TAVHGHVQVTLNQLFAYPYSATKVTTEEDAVGHVVDGTIDLEQSIIDAVGIELPFAPMC FT RSDCPGLCAECGTSLVVEPGHPHDRIDPWWAKLTDMLAPDVPQTSETDGSRSEW" FT CDS complement(3344..4087) FT /transl_table=11 FT /gene="ML1661" FT /product="conserved hypothetical protein" FT /note="Similar to several proteins of undefined function FT e.g. Mycobacterium tuberculosis RV2927C TR:YT27_MYCTU." FT /db_xref="UniProtKB/Swiss-Prot:Q9CBS6" FT /protein_id="CAC30614.1" FT /translation="MAVYRVFEALDELGAIVEEARGVPMTAGCVVPRGDVLELIDDIKD FT AIPGELDDAQDVLDARDAMLNDAKAHADSMVSSATTESESLLSHARAEADRILSDAKSQ FT VDRMASEARQHSERMLGDAREESIRIATVAKREYEASLNRAQSECDRLIENGNISYEKA FT IQEGIKEQQRLVSQNEVVQAANAESTRLIDTAHAEADRLRGECDIYVDNKLAEFEEFLN FT GTLRSVGRGRHQLRTAAGTHDYVTR" FT RBS complement(4090..4095) FT CDS 4317..4897 FT /pseudo FT /transl_table=11 FT /gene="ML1662" FT /product="integral membrane protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2963 (Best blastx score 136)" FT repeat_region 4905..6083 FT /note="1179 bp 100% identical to region 545582..544404" FT CDS complement(6182..6655) FT /transl_table=11 FT /gene="coaD" FT /gene_synonym="ML1663" FT /product="probable phosphopantetheine adenylyltransferase" FT /note="Highly similar to many phosphopantetheine FT adenylyltransferases (EC 2.7.7.3) involved in coenzyme A FT biosynthesis, including: Escherichia coli SW:COAD_ECOLI FT (P23875) (159 aa); Fasta score E(): 5.9e-25, 43.5% identity FT in 154 aa overlap and Mycobacterium tuberculosis RV2965C FT SW:COAD_MYCTU (Q50452) (161 aa); Fasta score E(): 0, 85.6% FT identity in 153 aa overlap. Contains Pfam match to entry FT PF01467 Cytidylyltransf, Cytidylyltransferase." FT /db_xref="GOA:O69466" FT /db_xref="HSSP:1QJC" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/Swiss-Prot:O69466" FT /protein_id="CAC30616.1" FT /translation="MVCPGSFDPVTLGHIDVFERAAAQFDEVVVAILINPVKKGMFDLD FT ERIAMINESTMHLPNLRVEAGEGLVVALVRSRGMTAIVKGLRTGVDFEYELQMAQMNKH FT IAGVDTFFVATAPRYSFVSSSLVKEVAMLGGDVSELLPESVNRRFREKMSGTS" FT misc_feature complement(6257..6652) FT /note="Pfam match to entry PF01467 Cytidylyltransf, FT Cytidylyltransferase, score 157.90, E-value 1.7e-43" FT CDS complement(6687..7160) FT /transl_table=11 FT /gene="ML1664" FT /product="conserved hypothetical protein" FT /note="Similar to several proteins of undefined function FT including: Neisseria meningitidis possible DNA methylase FT TR:CAB83466 (EMBL:AL162752) (189 aa); Fasta score E(): FT 3.6e-07, 39.6% identity in 96 aa overlap and Mycobacterium FT tuberculosis Rv2966c TR:P95128 (EMBL:Z83018) (188 aa); FT Fasta score E(): 0, 72.9% identity in 155 aa overlap. FT Contains PS00092 N-6 Adenine-specific DNA methylases FT signature." FT /db_xref="InterPro:IPR016065" FT /db_xref="UniProtKB/TrEMBL:Q9CBS5" FT /protein_id="CAC30617.1" FT /translation="MRESLFNIVAAQRELTGLAVLDLYAGSGALGLEALSRGAASTLFV FT ESDKRTVAVIERNVTALGLVGARPRCGPVATVLAAGTASPMDLVLADPPYAIDTAEVEA FT VLATLTTYGWARPGTVAVIERGAASVPLTWPAGWSSWQSRGYGDTRLELAELT" FT misc_feature complement(6876..6896) FT /note="PS00092 N-6 Adenine-specific DNA methylases FT signature" FT CDS complement(7241..10625) FT /pseudo FT /transl_table=11 FT /gene="pca" FT /gene_synonym="ML1665" FT /product="pyruvate carboxylase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT pca (Best blastx score 873)" FT CDS complement(10651..11295) FT /transl_table=11 FT /gene="ML1666" FT /product="conserved integral membrane protein" FT /note="Similar to several proteins of undefined function FT including: Streptomyces coelicolorputative integral FT membrane protein TR:CAB93387 (EMBL:AL357523) (240 aa); FT Fasta score E(): 3.6e-25, 36.1% identity in 191 aa overlap FT and Mycobacterium tuberculosis Rv2968c TR:P95126 FT (EMBL:Z83018) (210 aa); Fasta score E(): 0, 72.4% identity FT in 214 aa overlap. Contains possible membrane spanning FT hydrophobic domains." FT /db_xref="InterPro:IPR012932" FT /db_xref="UniProtKB/TrEMBL:O69464" FT /protein_id="CAC30619.1" FT /translation="MSAQPVERPGDLKPAPASVLPMPVPTAWWVLIAGVIGLVASMMLT FT VEKIRILLNSAYVPSCNVNPIVACGSVMSTPQASVLGFPNPLLGIVGFTLVTVTGVLSV FT AEVSLPQWYWIGLAVGTLAGVGFVHWLIFQSLYRIGALCAYCMVIWAVSVSLLVVVTAI FT VFRPLLEVLPGRTSAIARGIYQWRWSIATLWFITVFLLIMVRFWNYWQTLL" FT CDS complement(11304..12098) FT /transl_table=11 FT /gene="ML1667" FT /product="possible conserved membrane protein" FT /note="Similar to several proteins of undefined function FT e.g. Mycobacterium tuberculosis RV2969C TR:O33272 FT (EMBL:Z83018) (255 aa); Fasta score E(): 0, 65.5% identity FT in 258 aa overlap. Contains a possible membrane spanning FT hydrophobic domain." FT /db_xref="UniProtKB/TrEMBL:Q9CBS4" FT /protein_id="CAC30620.1" FT /translation="MRISEPVADNRKRLQRFDLKSVDGRSGRAVVIAGTVIVAIFAVVV FT VFAVMKSQHAKQDGAAPLTGSGDTVRVTSSKLVTQPGTHDPKVVMSFYEDFLCPGCGDF FT ERNFGPTVSKLIDIGAIAADYSVVSILDHPRNHNYPSRAGAASLCVADESMDAYRRFRA FT ALYSRSFQPSELASSFPENAKLIEIAREAGVVGKVPDCINSGKYLAKVTAEAALAKISA FT TPTIKINGDEYDPLTPEALVAKIKAIVGAVPGIDVAVTATTT" FT CDS complement(12342..13124) FT /pseudo FT /transl_table=11 FT /gene="lipN" FT /gene_synonym="ML1668" FT /product="probable lipase/esterase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT lipN (Best blastx score 135)" FT CDS 14106..14954 FT /transl_table=11 FT /gene="ML1669" FT /product="possible oxidoreductase of Aldo/keto reductase FT family" FT /note="Highly similar to many putative oxidoreductases FT including: Escherichia coli SW:YQHE_ECOLI (Q46857) (275 FT aa); Fasta score E(): 0, 46.1% identity in 271 aa overlap FT and Mycobacterium tuberculosis RV2971 TR:P95124 FT (EMBL:Z83018) (282 aa); Fasta score E(): 0, 79.8% identity FT in 282 aa overlap. Contains Pfam match to entry PF00248 FT aldo_ket_red, Aldo/keto reductase family. Contains PS00062 FT Aldo/keto reductase family signature 2." FT /db_xref="GOA:O69462" FT /db_xref="HSSP:1HW6" FT /db_xref="InterPro:IPR018170" FT /db_xref="UniProtKB/Swiss-Prot:O69462" FT /protein_id="CAC30622.1" FT /translation="MMPSTPRTSIPSITLNDENTMPLLGLGVAELSEDETERAVLAALE FT IGCRLIDTAAAYGNEAAVSRAIAASGIPRAQLFVTTKLATPDQGFTKSQDACNASLDRL FT GMDYVDLYLIHWPAPPVGQYVDAWGGMIQSRGEGHARSIGVCNFTEEHLSAIIDLTFVT FT PAVNQIELHPLLNQDEMRKSNAQHNVITQSYTPLVLGRLMDNSTLTAIAAEYGKTPAQV FT LLRWNLQLGNAVVFRSAKAEHIASNFDVFDFELAVNHMDAMNELHDGTRLRPDPETYAG FT S" FT misc_feature 14148..14918 FT /note="Pfam match to entry PF00248 aldo_ket_red, Aldo/keto FT reductase family, score 448.60, E-value 5.4e-131" FT misc_feature 14496..14549 FT /note="PS00062 Aldo/keto reductase family signature 2" FT CDS complement(15025..15682) FT /pseudo FT /transl_table=11 FT /gene="ML1670" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2972c (Best blastx score 445)" FT CDS complement(15773..18004) FT /transl_table=11 FT /gene="recG" FT /gene_synonym="ML1671" FT /product="ATP-dependent DNA helicase" FT /note="Highly similar to many ATP-dependent DNA helicases FT including: Staphylococcus aureus SW:RECG_STAAU (O50581) FT (686 aa); Fasta score E(): 2e-24, 35.7% identity in 701 aa FT overlap and Mycobacterium tuberculosis RV2973C FT SW:RECG_MYCTU (P95122) (737 aa); Fasta score E(): 0, 79.4% FT identity in 744 aa overlap. Contains Pfam match to entry FT PF00271 helicase_C, Helicases conserved C-terminal domain. FT Contains Pfam match to entry PF00270 DEAD, DEAD/DEAH box FT helicase. Contains PS00017 ATP/GTP-binding site motif A FT (P-loop)." FT /db_xref="GOA:O69460" FT /db_xref="HSSP:1GM5" FT /db_xref="InterPro:IPR004365" FT /db_xref="UniProtKB/Swiss-Prot:O69460" FT /protein_id="CAC30624.1" FT /translation="MVSLSDRLDYIVGAKAADSLDEVFGIRTVDDLLRHYPRSYTKGAT FT VRGAQDERPEAGEHITIVDVITEAVTLPMKKDSKKKYLRLTVGSGRNKVIATFFNAGYI FT SKGLTKDTRVMLSGEVGFFRGVMQLTHPAFLILDSPDGRNRGSSSLRRIADASQAVSGE FT VLMSAFERRFFPIYPASTKLQSWDIYACVRQVLEVLDPVADPLPADLRAKHGLVSEDEA FT LRAIHLAESESDRRRARERLTFDEAVGLQWALVTRRHGELSESGPSAPPRSDGLMAELM FT RRLPFELTEGQREVRDVLSDGLAATRPLNRLLQGEVGSGKTIVAVLAMLQMIDAGYQCV FT LLAPTEVLAAQHLLSIRDVLGPLGMGCQLGGAENATQVALLTGSMTMAQKKKVRADIFS FT GQTGIVIGTHALLQDAIEFHNLGMVVVDEQHRFGVEQRDQLRTKARTGIMPHLLVMTAT FT PIPRTVALTVYGDLEMSTLRELPRGRQPITSNVIFVKDKPGWLDRAWQRILEEVAAGRQ FT AYVVAPRIDETEDPQKGGQNSRPSETADGLYARLRSGELANVRLALMHGRLSADEKDAA FT MMAFRAGEIDVLVCTNVIEVGVDVPNATIMLVMDADRFGISQLHQLRGRIGRGTHPSLC FT LLASWVSPGSPAGRRLCAVAETMDGFALADLDLKERREGDVLGRNQSGKAITLRMLSLA FT EHQVFIEAARDFCTRAYEYPHLGLAPHPGLADLAARFIDTDRIEYLGKS" FT misc_feature complement(16115..16372) FT /note="Pfam match to entry PF00271 helicase_C, Helicases FT conserved C-terminal domain, score 65.00, E-value 1.5e-15" FT misc_feature complement(16484..17173) FT /note="Pfam match to entry PF00270 DEAD, DEAD/DEAH box FT helicase, score 102.20, E-value 2.2e-31" FT misc_feature complement(17039..17062) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(18010..19441) FT /pseudo FT /transl_table=11 FT /gene="ML1672" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2974c (Best blastx score 719)" FT CDS complement(19492..19692) FT /pseudo FT /transl_table=11 FT /gene="ML1673" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2975c (Best blastx score 88)" FT CDS 19956..20222 FT /pseudo FT /transl_table=11 FT /gene="rpmB" FT /gene_synonym="ML1674" FT /product="50S ribosomal protein L28 (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT rpmB (Best blastx score 125)" FT CDS complement(20327..21010) FT /transl_table=11 FT /gene="ung" FT /gene_synonym="ML1675" FT /product="uracil-DNA glycosylase" FT /note="Highly similar to many uracil-DNA glycosylases FT including: Streptococcus pneumoniae SW:UNG_STRPN (P23379) FT (123 aa); BlastP Expect 8.6 and Mycobacterium tuberculosis FT SW:UNG_MYCTU (P95119) (227 aa); Fasta score E(): 0, 88.5% FT identity in 227 aa overlap. Contains Pfam match to entry FT PF00315 UNG, Uracil-DNA glycosylase. Contains PS00130 FT Uracil-DNA glycosylase signature." FT /db_xref="GOA:Q9CBS3" FT /db_xref="HSSP:1FLZ" FT /db_xref="InterPro:IPR005122" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBS3" FT /protein_id="CAC30628.1" FT /translation="MTARPLSELVEQGWAAALEPVVDQVAEMGRFLRAEIAAGRRYLPA FT GHSVLRAFTYPFDNVRVLIVGQDPYPTPGHAVGLSFSVAPDVRPLPRSLANVFDEYTAD FT LGYPLPVCGDLTPWAQRGVLLLNRVLTVRPSNPASHRGKGWEVITECAIRALAARSEPM FT VAILWGRDAATLKPLLTVDNCVVIESPHPSPLSASRGFFGSRPFSRTNEILVGMGAGPI FT NWRLP" FT misc_feature complement(20339..20881) FT /note="Pfam match to entry PF00315 UNG, Uracil-DNA FT glycosylase, score 210.30, E-value 2.8e-59" FT misc_feature complement(20801..20830) FT /note="PS00130 Uracil-DNA glycosylase signature" FT CDS complement(21124..22101) FT /transl_table=11 FT /gene="thiL" FT /gene_synonym="ML1676" FT /product="probable thiamine-monophosphate kinase" FT /note="Similar to several thiamine-monophosphate kinases FT (EC 2.7.4.16) including: Escherichia coli SW:THIL_ECOLI FT (P77785) (325 aa); Fasta score E(): 1.1e-18, 35.3% identity FT in 278 aa overlap and Mycobacterium tuberculosis RV2977C FT TR:P95118 (P95118) (333 aa); Fasta score E(): 0, 80.9% FT identity in 314 aa overlap. Contains Pfam match to entry FT PF00586 AIRS, AIR synthase related protein." FT /db_xref="GOA:Q9CBS2" FT /db_xref="InterPro:IPR000728" FT /db_xref="UniProtKB/TrEMBL:Q9CBS2" FT /protein_id="CAC30629.1" FT /translation="MCNHECGALGESVTLEQLGEFAVIDRLVRGRRQPAVVALGPGDDA FT AVVTASDGRIVVSTDVLVQDRHFRLDWSTPHDVGRKAIAQNAADIEAMGARATTFVVGL FT GAPGDTPVAQVDALVDGLWDEAGRIGAGIVGGDLVSCPQWVLSVTVLGDLDGRAPVLRS FT GAKNGSMVAVAGALGRSAAGYALWHKGIDGFDDLRRRHLVPEPPYGKGVAAAACGAQAM FT IDVSDGLIADLRHVARASGVSIDLSTAALAADHAALIAAATAVGGDPWPWVLGGGEDHA FT LVACFAGTALSGWRIIGRVFDGPARVLVDGQEWRGHAGWQSFGG" FT misc_feature complement(21196..22044) FT /note="Pfam match to entry PF00586 AIRS, AIR synthase FT related protein, score -13.40, E-value 5.4e-06" FT CDS 22285..22860 FT /transl_table=11 FT /gene="ML1677" FT /product="possible secreted protein" FT /note="Highly similar to Mycobacterium tuberculosis FT hypothetical protein Rv2980 TR:P95115 (EMBL:Z83018) (181 FT aa); Fasta score E(): 0, 67.2% identity in 177 aa overlap. FT Contains a possible N-terminal signal sequence." FT /db_xref="UniProtKB/TrEMBL:Q9CBS1" FT /protein_id="CAC30630.1" FT /translation="MTSNSDAGSAVDAGGPPRTVIIAAVVLTAATIGTILVLAATLHEP FT PQPVVITAVPAPQATTAACRSLTQALPQRLGDYERAPVAQPAPDAVAAWRTGSDTEPVV FT LRCGLDGPAEFVVGSPIQAVDQVQWFEVDAKPKPAIDAGRSTWYTVDRPVYVALTLPSG FT SGPTPIQELSDVIDRTLAAIPISPAQSH" FT CDS complement(22869..24023) FT /transl_table=11 FT /gene="ddlA" FT /gene_synonym="ML1678" FT /product="D-alanine-D-alanine ligase A" FT /note="Highly similar to D-alanine--D-alanine ligase A (EC FT 6.3.2.4) from many including: Salmonella typhimurium FT SW:DDLA_SALTY (P15051) (363 aa); Fasta score E(): 0, 43.5% FT identity in 368 aa overlap and Mycobacterium tuberculosis FT SW:DDL_MYCTU (P95114) (373 aa); Fasta score E(): 0, 81.7% FT identity in 367 aa overlap. Contains Pfam match to entry FT PF01820 Dala_Dala_ligas, D-ala D-ala ligase. Contains FT PS00844 D-alanine--D-alanine ligase signature 2. Contains FT PS00843 D-alanine--D-alanine ligase signature 1." FT /db_xref="GOA:Q9CBS0" FT /db_xref="HSSP:1E4E" FT /db_xref="InterPro:IPR013817" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBS0" FT /protein_id="CAC30631.1" FT /translation="MNVYQRPLMPWLPSGGRVRVAVVFGGRSNEHAVSCLSAGSILRNL FT DRQRFDVVAVGITPEGTWMLTDPNPDALAIANRQLPAVSCESGIELTLPADPRRSGQLV FT SLSHGAGLGAGEVLTSVDVVFPVLHGPYGEDGTIQGLLELARVPYVGAGVLASAAGMDK FT EFTKKLFAAEGLPLSAYTVLRPLRPTLHRQECERLSLPVFVKPARGGSSIGISRVSSWG FT QLPSAIAYARRHDPKVIVEAAVNGRELECGVLEMPDGTVAASAVGEIRVAGVSGSEDSF FT YDFTTKYLDDAAELDVPAKVDDDVADEVRQLAIQAFRAIDCQGLARVDFFLTDDGPVIN FT EINTMPGFTMTSMYPKLWAVSSVDYPTLLATMVDTALARGVGMR" FT misc_feature complement(22902..23972) FT /note="Pfam match to entry PF01820 Dala_Dala_ligas, D-ala FT D-ala ligase, score 565.30, E-value 3.9e-166" FT misc_feature complement(22983..23066) FT /note="PS00844 D-alanine--D-alanine ligase signature 2" FT misc_feature complement(23604..23639) FT /note="PS00843 D-alanine--D-alanine ligase signature 1" FT CDS complement(24135..25190) FT /transl_table=11 FT /gene="gpdA" FT /gene_synonym="ML1679" FT /product="glycerol-3-phosphate dehydrogenase" FT /note="Highly similar to many glycerol-3-phosphate FT dehydrogenases (EC 1.1.1.8) including: Escherichia coli FT SW:GPDA_ECOLI (P37606) (339 aa); Fasta score E(): 0, 39.9% FT identity in 341 aa overlap and Mycobacterium tuberculosis FT RV2982C TR:P95113 (EMBL:Z83018) (334 aa); Fasta score E(): FT 0, 77.9% identity in 349 aa overlap. Contains Pfam match to FT entry PF01210 NAD_Gly3P_dh, NAD-dependent FT glycerol-3-phosphate dehydrogenase." FT /db_xref="GOA:Q9CBR9" FT /db_xref="HSSP:1EVY" FT /db_xref="InterPro:IPR006109" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBR9" FT /protein_id="CAC30632.1" FT /translation="MEMAGIVVRSESAVAVMGAGAWGTALAKVLIDAGGPEAGVVLWAR FT RPDVAERINTTRCNRAYLPGTLLPPGIRATADPADALRGASTVLLGVPAQRMRANLERW FT GGLVADGATLVSLAKGIELGTLMRMSQVIVSVTGVDPAQVAVLSGPNLASEIAQCQPAA FT TVIACSDLGRAVALQRMLSSGYFRPYTNSDVVGTEIGGVCKNVIALACGMAAGVGFGEN FT TAATIITRGLAEIIRLGMALGAQVTTLAGLAGVGDLVATCTSPHSRNRSLGERLGRGEI FT MQSILHGMDGSDGGDGYVVEGVTSCASVLALASSYDVEMPLTDAVHRVCHKGLSVEKAM FT ALLLGRSTKSE" FT misc_feature complement(24162..25163) FT /note="Pfam match to entry PF01210 NAD_Gly3P_dh, FT NAD-dependent glycerol-3-phosphate dehydrogenase, score FT 273.70, E-value 2.5e-78" FT CDS 25731..26381 FT /transl_table=11 FT /gene="ML1680" FT /product="conserved hypothetical protein" FT /note="Highly similar to several proteins of undefined FT function including: Mycobacterium tuberculosis RV2983 FT TR:P95112 (EMBL:Z83018) (214 aa); Fasta score E(): 0, 79.1% FT identity in 215 aa overlap and Streptomyces coelicolor FT TR:Q9ZBS2 (EMBL:AL034447) (212 aa); Fasta score E(): FT 1.2e-17, 41.1% identity in 207 aa overlap. Contains Pfam FT match to entry PF01983 DUF121, Protein of unknown FT function." FT /db_xref="InterPro:IPR002835" FT /db_xref="UniProtKB/TrEMBL:O33128" FT /protein_id="CAC30633.1" FT /translation="MSGTRAGGTADVGLIIAVKRLAAAKTRLGPVFSTRTRENVVLAML FT VDTLTAAAPVSALRSITVITPDEAAAAAAAEFGAEILADPTPDGHGDPLNNAIAAAEHA FT IAGSFSNIVVLQGDLPALQTQELSEAIAAARHHQRSFVADRLGSGTAALCTFGTALNPQ FT FGPDSSAQHRRSGAIELTGPWPGLRCDVDTPADLAAARRLGIGAATTRVVAHL" FT misc_feature 25764..26378 FT /note="Pfam match to entry PF01983 DUF121, Protein of FT unknown function, score -39.30, E-value 0.00041" FT CDS 26465..28684 FT /transl_table=11 FT /gene="ML1681" FT /product="possible polyphosphate kinase" FT /note="Highly similar to many polyphosphate kinases (EC FT 2.7.4.1) including: Escherichia coli SW:PPK_ECOLI (P28688) FT (687 aa); Fasta score E(): 0, 34.4% identity in 655 aa FT overlap and Mycobacterium tuberculosis RV2984 TR:P95111 FT (EMBL:Z83018) (742 aa); Fasta score E(): 0, 87.9% identity FT in 742 aa overlap." FT /db_xref="GOA:O33127" FT /db_xref="InterPro:IPR003414" FT /db_xref="UniProtKB/Swiss-Prot:O33127" FT /protein_id="CAC30634.1" FT /translation="MMSNDLLVTDIEAEARTEENIWHSDNSALAAPPAATTSASQDQLP FT DDRYLNRESSWLDFNARVLALAADNSLPLLERAKFLAIFASNLDEFYMVRVAGLKRRDE FT MDLSVRSADGLTPREQLSRIGEQTQWIASRHARVFLDSVLPALGEEGIYIVTWTDLDQA FT ERDQLSTYFNEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVTVKQPEDGTQHFARVKVPN FT NVDRFVELANRGAVRDTSAGDEGQLIHRFLPMEELIAAFLPVLFPGTEIVEHHAFRITR FT NADFEVEEDRDEDLLQALERELARRRFGSPVRLEIADDMTESMLELLLRELDVHPSDVI FT EVPGLLDLSSLWQIYGLDRPALKDRAFIPDTHPAFAERETPKSIFATLREGDVLVHHPY FT HSFATSVQRFIEQATADPDVLAIKQTLYRTSGDSPIVLALIEAAEAGKQVVALVEIKAR FT FDEQANIRWARALEHAGVHVVYGIVGLKTHCKTCLVVRREGPTIRRYCHIGTGNYNSKT FT ARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKLAYRNLLVAPYGIRRGIIERVEREVA FT AHRESGPQTGKGLIRLKMNALVDEQVIDALYRASQAGVRVEVVVRGICALRPGTEGFSE FT NIFVRSILGRFLEHSRIIHFRAIDEFWIGSADMMHRNLDRRVEVLAQVKDSRLTAQLDE FT LLKSALDPFTRCWELRPDGQWTASPQKGQQVRDHQESLMERHRSR" FT CDS 28763..29698 FT /transl_table=11 FT /gene="ML1682" FT /product="conserved hypothetical protein" FT /note="Similar to several proteins of undefined function FT e.g. Mycobacterium tuberculosis TR:P95110 (EMBL:Z83018) FT (317 aa); Fasta score E(): 0, 71.5% identity in 316 aa FT overlap and Streptomyces coelicolor putative MutT-like FT protein TR:CAB88476 (EMBL:AL353816) (142 aa); Fasta score FT E(): 2.6e-17, 47.7% identity in 128 aa overlap. Contains FT Pfam match to entry PF00293 mutT, Bacterial mutT protein. FT Contains PS00893 mutT domain signature." FT /db_xref="GOA:Q9CBR8" FT /db_xref="HSSP:1KT9" FT /db_xref="InterPro:IPR020084" FT /db_xref="UniProtKB/TrEMBL:Q9CBR8" FT /protein_id="CAC30635.1" FT /translation="MAIWNSSCQWPKSQIVYAAGAVLWRPGNSDPAVEIAVIHRPRYDD FT WSLSKGKVDPGETAPMAAVREVFEETGHHATLGARLVVVNYPIGQHVKKVYYWAARSIE FT GQFVPGSEVDELLWLPVVDAMKKLDYVQDRKVLRQFAKQPAYTRTVLIVRHGTAGRKSR FT LSEDDTKRPLDKQGRAQAEALIGQLLAFGATDVYAADQLHCHQTVEPLAAELGVPIHNE FT PSLTKEAFAKNPKRGLHRVLRIAAQSGTPVICLQGKIIPDLIAWWCERDGVRPKKSHNY FT KGSTWVLSLLAGQLVAVDHVGSTLAANVQP" FT misc_feature 28865..28981 FT /note="Pfam match to entry PF00293 mutT, Bacterial mutT FT protein, score 42.70, E-value 9.3e-11" FT misc_feature 28913..28972 FT /note="PS00893 mutT domain signature" FT CDS complement(29767..30369) FT /transl_table=11 FT /gene="ML1683" FT /product="probable histone-like protein" FT /note="The N-terminus of the predicted product of this CDS FT is highly similar to many bacterial histone-like FT DNA-binding proteins e.g. Bacillus stearothermophilus FT SW:DBH_BACST (P02346) (90 aa); Fasta score E(): 2e-09, FT 48.3% identity in 89 aa overlap Similar over the whole FT range to Mycobacterial histone-like proteins e.g. FT Mycobacterium smegmatis TR:Q9ZHC5 (EMBL:AF068138) (269 aa); FT BlastP Expect 0.0014 and Mycobacterium tuberculosis RV2986C FT SW:DBH_MYCTU (P95109) (214 aa); Fasta score E(): 0, 80.1% FT identity in 216 aa overlap. Note that the C-terminus is FT rich in the amino acids Ala, Val and Lys. Contains Pfam FT match to entry PF00216 Bac_DNA_binding, Bacterial FT DNA-binding protein. Contains PS00045 Bacterial FT histone-like DNA-binding proteins signature." FT /db_xref="GOA:O33125" FT /db_xref="HSSP:1HUU" FT /db_xref="InterPro:IPR000119" FT /db_xref="UniProtKB/Swiss-Prot:O33125" FT /protein_id="CAC30636.1" FT /translation="MNKAELIDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTIT FT GFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFRPGAQFKAVVAGAQRLPLEGPAVKR FT GVATSAAKKAAIKKAPVKKALAKKAATKAPAKKAVKAPAKKITTAVKVPAKKATKVVKK FT VAAKAPVRKATTRALAKKAAVKKAPAKKVTAAKRGRK" FT misc_feature complement(30100..30369) FT /note="Pfam match to entry PF00216 Bac_DNA_binding, FT Bacterial DNA-binding protein, score 121.40, E-value FT 9.5e-34" FT misc_feature complement(30175..30234) FT /note="PS00045 Bacterial histone-like DNA-binding proteins FT signature" FT RBS complement(30376..30380) FT CDS complement(30583..31179) FT /transl_table=11 FT /gene="leuD" FT /gene_synonym="ML1684" FT /product="3-isopropylmalate dehydratase small subunit" FT /note="Highly similar to many 3-isopropylmalate dehydratase FT small subunits (EC 4.2.1.33) involved in leucine FT biosynthesis, including: Escherichia coli SW:LEUD_ECOLI FT (P30126) (201 aa); Fasta score E(): 1.2e-28, 42.1% identity FT in 197 aa overlap and Mycobacterium tuberculosis RV2987C FT SW:LEUD_MYCTU (O53236) (198 aa); Fasta score E(): 0, 87.8% FT identity in 196 aa overlap. Contains Pfam match to entry FT PF00694 Aconitase_C, Aconitase C-terminal domain." FT /db_xref="GOA:O33124" FT /db_xref="InterPro:IPR000573" FT /db_xref="UniProtKB/Swiss-Prot:O33124" FT /protein_id="CAC30637.1" FT /translation="MQAFRVHTGIGVPLRRSNVDTDQIIPAVFLKRVTRNGFEDGLFAT FT WRVDPSFVLNLSPFDRGSVLVVGPDFGIGSSREHAVWALMDYGFRVVISSRFGDIFHGN FT AGKAGLLAAQVAQDDVEFLWKLIEQKPGLEITVNLQDRNINAATVVLPFKIDDYTAWRL FT LEGLDDIALNLRKLDEIEAFESARPAWKPRTLPTT" FT misc_feature complement(30694..31179) FT /note="Pfam match to entry PF00694 Aconitase_C, Aconitase FT C-terminal domain, score 113.60, E-value 3.6e-30" FT RBS complement(31187..31191) FT CDS complement(31222..32679) FT /transl_table=11 FT /gene="leuC" FT /gene_synonym="ML1685" FT /product="3-isopropylmalate dehydratase large subunit" FT /note="Highly similar to many 3-isopropylmalate dehydratase FT large subunits (EC 4.2.1.33) involved in leucine FT biosynthesis, including: Escherichia coli SW:LEU2_ECOLI FT (P30127) (465 aa); Fasta score E(): 0, 61.3% identity in FT 463 aa overlap and Mycobacterium tuberculosis RV2988C FT SW:LEU2_MYCTU (O53237) (473 aa); Fasta score E(): 0, 88.7% FT identity in 471 aa overlap. Contains Pfam match to entry FT PF00330 aconitase, Aconitase family (aconitate hydratase). FT Contains PS01244 Aconitase family signature 2. Contains FT PS00450 Aconitase family signature 1." FT /db_xref="GOA:O33123" FT /db_xref="InterPro:IPR015936" FT /db_xref="UniProtKB/Swiss-Prot:O33123" FT /protein_id="CAC30638.1" FT /translation="MEMDNERKQVGGARKPRTLAEKVWDDHVVVAGQGYHQDRGPDLIY FT IDLHLVHEVTSPQAFDGLRLAGRWVRRPDLTVATEDHNVPTVDIDKPIADPVSRIQVET FT LRRNCAEFGVRLHPMGDIEQGIVHVVGPQLGLTQPGMTIVCGDSHTSTHGAFGAIAMGI FT GTSEIEHVLATQTLPLRPFKTMAVTVDGRLPAGVTAKDIILALIAKIGTGGGQGYVLEY FT RGSVIESMSMEGRMTICNMSIEAGARAGMVAPDETTYEFLRDRPHAPTGKQWDAAVAYW FT QQLRTDDDAVFDTEVYLDATSLSPFVTWGTNPGQGVPLAASVPDPELMIDDVARQAAEK FT ALAYMDLRPGTPMRDIAVDAVFVGSCTNGRIEDLRLVADVLRGHKVADGVRMLIVPGSM FT RVRAQAEAEGLGEIFITAGAQWRQPGCSMCLGMNPDQLAPGERCAATSNRNFEGRQGKG FT GRTHLVSPAVAAATAVRGTFSAPADLN" FT misc_feature complement(31252..32628) FT /note="Pfam match to entry PF00330 aconitase, Aconitase FT family (aconitate hydratase), score 754.90, E-value FT 3.9e-230" FT misc_feature complement(31387..31428) FT /note="PS01244 Aconitase family signature 2" FT misc_feature complement(31558..31608) FT /note="PS00450 Aconitase family signature 1" FT CDS 32757..33464 FT /pseudo FT /transl_table=11 FT /gene="ML1686" FT /product="transcriptional regulator (IclR family) FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2989 (Best blastx score 788)" FT CDS 33749..33880 FT /pseudo FT /transl_table=11 FT /gene="ML1687" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2991" FT tRNA complement(34156..34231) FT /gene="gluU" FT /note="tRNA Glu anticodon CTC, Cove score 62.17" FT tRNA complement(34319..34393) FT /gene="glnU" FT /note="tRNA Gln anticodon CTG, Cove score 56.59" FT CDS complement(34634..36142) FT /transl_table=11 FT /gene="gltS" FT /gene_synonym="ML1688" FT /product="glutamyl-tRNA synthase" FT /note="Highly similar to many glutamyl-tRNA synthetases (EC FT 6.1.1.17) including: Bacillus subtilis SW:SYE_BACSU FT (P22250) (483 aa); Fasta score E(): 0, 37.4% identity in FT 486 aa overlap and Mycobacterium tuberculosis RV2992C FT SW:SYE_MYCTU (O53241) (490 aa); Fasta score E(): 0, 81.4% FT identity in 488 aa overlap. Contains Pfam match to entry FT PF00749 tRNA-synt_1c, tRNA synthetases class I (E and Q)." FT /db_xref="GOA:O33120" FT /db_xref="HSSP:1J09" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/Swiss-Prot:O33120" FT /protein_id="CAC30641.1" FT /translation="MTAVTSDGTPQAAKVRVRFCPSPTGVPHVGMVRTALFNWAYARHT FT GGTFVLRIEDTDADRDSEESYLALLDALRWLGLNWDEGPEVGGPYGPYRQSQRTDIYRE FT VVAKLLATGEAYYAFSTPEEVENRHLAAGRNPKLGYDNFDRDLTDAQFSAYLAEGRKPV FT VRLRMPDEDISWDDLVRGTTTFAVGTVPDYVLTRASGDPLYTLVNPCDDALMKITHVLR FT GEDLLSSTPRQVALYQALIRIGMAERIPEFGHFPSVLGEGTKKLSKREPQSNLFAHRDR FT GFIPEGLLNYLALLGWAIADDHDLFSLDEMVAAFDVVDVNSNPARFDQKKADAVNAEHI FT RMLDSEDFAGRLRDYFTTHGYHIALDPANYEAGFVAAAQLVQTRIVVLGDAWDLLKFLN FT DDEYSIDSKAAAKELDADAGPVLDVACAVLDSLVDWTTASIEDVLKVALIEGLGLKPRK FT VFGPIRVAATGALVSPPLFESLELLGRARSLQRLSAARARVTSA" FT misc_feature complement(34655..36103) FT /note="Pfam match to entry PF00749 tRNA-synt_1c, tRNA FT synthetases class I (E and Q), score 379.80, E-value FT 2.7e-110" FT CDS complement(36139..36867) FT /transl_table=11 FT /gene="ML1689" FT /product="possible hydrolase" FT /note="Similar in parts to several putative FT 2-hydroxyhepta-2,4-diene-1,7-dioate isomerases including: FT Methanobacterium thermoautotrophicum TR:O27551 FT (EMBL:AE000911) (260 aa); Fasta score E(): 0, 51.9% FT identity in 216 aa overlap and Mycobacterium tuberculosis FT RV2993C TR:O53242 (EMBL:AL021287) (239 aa); Fasta score FT E(): 0, 85.9% identity in 241 aa overlap. Contains Pfam FT match to entry PF01557 FAA_hydrolase, Fumarylacetoacetate FT (FAA) hydrolase family." FT /db_xref="GOA:O33119" FT /db_xref="HSSP:1GTT" FT /db_xref="InterPro:IPR018833" FT /db_xref="UniProtKB/TrEMBL:O33119" FT /protein_id="CAC30642.1" FT /translation="MFARELAEYPFGELTFTGRSWPLADVRLLAPMLASKVVCIGKNYA FT DHIVEMGGQTGLASADPVIFLKPNTAIIGPNVPIRLPANASPVHFEGELALVVGRSCKD FT VPAVQAVDCILGYTIGNDMSARDQQRADGQWTRAKGHDTFCPVGPWIVTDLGPLDPADL FT ELRTAVNGEVKQHSRTSLMIHGIGAIMEWISAVMTLLPGDLILTGTPAGVGPVEDGDIV FT SITVEGIGTLTNPVVRKGKS" FT misc_feature complement(36214..36717) FT /note="Pfam match to entry PF01557 FAA_hydrolase, FT Fumarylacetoacetate (FAA) hydrolase family, score 338.60, FT E-value 6.8e-98" FT CDS 37048..38350 FT /pseudo FT /transl_table=11 FT /gene="ML1690" FT /product="probable fluoroquinolone efflux protein FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2994 (Best blastx score 382)" FT CDS complement(38205..39215) FT /transl_table=11 FT /gene="leuB" FT /gene_synonym="ML1691" FT /product="3-isopropylmalate dehydrogenase" FT /note="Highly similar to 3-isopropylmalate dehydrogenases FT (EC 1.1.1.85), involved in leucine biosynthesis, from FT Mycobacterium bovis SW:LEU3_MYCBO (P94929) (336 aa); Fasta FT score E(): 0, 83.9% identity in 336 aa overlap and FT Mycobacterium tuberculosis RV2995C SW:LEU3_MYCTU (P95313) FT (336 aa); Fasta score E(): 0, 83.9% identity in 336 aa FT overlap. Contains Pfam match to entry PF00180 isodh, FT Isocitrate and isopropylmalate dehydrogenases." FT /db_xref="GOA:O33117" FT /db_xref="HSSP:1XAA" FT /db_xref="InterPro:IPR001804" FT /db_xref="UniProtKB/Swiss-Prot:O33117" FT /protein_id="CAC30644.1" FT /translation="MKLAIIGGDGIGPEVVAQAVKILDVVLPGVQKTTYDLGARRYHTT FT GELLPESVLAELREHDAILLGAVGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPG FT VNSLLAGKPDIDFVVVREGTEGPYTGTGGAIRVGTPNEVATEVSVNTAFGVRRVVQDAF FT ERARQRRKHLTLVHKNNVLTYAGTLWCRIVQEVGEKYPDVEVVYQHIDAATIYLVTEPS FT RFDVIVTDNLFGDIITDLAAAVCGGIALAASGNIDATRTNPSMFEPVHGSAPDIAGQGI FT ADPTAAIMSLALLLAHLGEDEPAARLDQAVASYLATRGNGRFSTGEVGERIAAAL" FT misc_feature complement(38220..39212) FT /note="Pfam match to entry PF00180 isodh, Isocitrate and FT isopropylmalate dehydrogenases, score 298.90, E-value FT 1.6e-88" FT CDS complement(39265..40851) FT /transl_table=11 FT /gene="serA" FT /gene_synonym="ML1692" FT /product="D-3-phosphoglycerate dehydrogenase" FT /note="Highly similar to many D-3-phosphoglycerate FT dehydrogenases (EC 1.1.1.95) involved in serine FT biosynthesis including: Bacillus subtilis SW:SERA_BACSU FT (P35136) (525 aa); Fasta score E(): 0, 36.1% identity in FT 527 aa overlap and Mycobacterium tuberculosis RV2996C FT SW:SERA_MYCTU (O53243) (528 aa); Fasta score E(): 0, 89.6% FT identity in 528 aa overlap. Contains Pfam match to entry FT PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid FT dehydrogenases. Contains Pfam match to entry PF01842 ACT, FT ACT domain. Contains PS00065 D-isomer specific FT 2-hydroxyacid dehydrogenases NAD-binding signature. FT Contains PS00670 D-isomer specific 2-hydroxyacid FT dehydrogenases signature 2. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop). Contains PS00671 FT D-isomer specific 2-hydroxyacid dehydrogenases signature FT 3." FT /db_xref="GOA:O33116" FT /db_xref="HSSP:1HKU" FT /db_xref="InterPro:IPR015508" FT /db_xref="UniProtKB/Swiss-Prot:O33116" FT /protein_id="CAC30645.1" FT /translation="MDLPVVLIADKLAQSTVAALGDQVEVRWVDGPDRTKLLAAVPEAD FT ALLVRSATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAE FT HALALLLAASRQIAEADASLRAHIWKRSSFSGTEIFGKTVGVVGLGRIGQLVAARIAAF FT GAHVIAYDPYVAPARAAQLGIELMSFDDLLARADFISVHLPKTPETAGLIDKEALAKTK FT PGVIIVNAARGGLVDEVALADAVRSGHVRAAGLDVFATEPCTDSPLFELSQVVVTPHLG FT ASTAEAQDRAGTDVAESVRLALAGEFVPDAVNVDGGVVNEEVAPWLDLVCKLGVLVAAL FT SDELPASLSVHVRGELASEDVEILRLSALRGLFSTVIEDAVTFVNAPALAAERGVSAEI FT TTGSESPNHRSVVDVRAVASDGSVVNIAGTLSGPQLVQKIVQVNGRNFDLRAQGMNLVI FT RYVDQPGALGKIGTLLGAAGVNIQAAQLSEDTEGPGATILLRLDQDVPGDVRSAIVAAV FT SANKLEVVNLS" FT misc_feature complement(39271..39492) FT /note="Pfam match to entry PF01842 ACT, ACT domain, score FT 44.00, E-value 3.4e-09" FT misc_feature complement(40015..40629) FT /note="Pfam match to entry PF00389 2-Hacid_DH, D-isomer FT specific 2-hydroxyacid dehydrogenases, score 257.90, FT E-value 2.7e-105" FT misc_feature complement(40141..40191) FT /note="PS00671 D-isomer specific 2-hydroxyacid FT dehydrogenases signature 3" FT misc_feature complement(40210..40278) FT /note="PS00670 D-isomer specific 2-hydroxyacid FT dehydrogenases signature 2" FT misc_feature complement(40339..40422) FT /note="PS00065 D-isomer specific 2-hydroxyacid FT dehydrogenases NAD-binding signature" FT misc_feature complement(40423..40446) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 40972..42216 FT /pseudo FT /transl_table=11 FT /gene="ML1693" FT /product="putative dehydrogenase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2997 (Best blastx score 314)" FT repeat_region 42777..43790 FT /note="REPLEP region 11, 5-end most similar to REPLEP 2, 5 FT and 6; 3'-end most similar to REPLEP 2" FT repeat_region 42845..43724 FT /note="Dispersed repeat, REPLEP, copy 11" FT repeat_region 43725..43752 FT /note="28 bp subsequence of 45 bp REPLEP-associated FT sequence" FT CDS complement(43770..44771) FT /transl_table=11 FT /gene="ilvC" FT /gene_synonym="ML1694" FT /product="ketol-acid reductoisomerase" FT /note="Highly similar to many ketol-acid reductoisomerases FT (EC 1.1.1.86) involved in valine and isoleucine FT biosynthesis, including: Mycobacterium avium SW:ILVC_MYCAV FT (Q59500) (333 aa); Fasta score E(): 0, 89.2% identity in FT 333 aa overlap and Mycobacterium tuberculosis RV3001C FT SW:ILVC_MYCTU (O53248) (333 aa); Fasta score E(): 0, 86.2% FT identity in 333 aa overlap. Contains Pfam match to entry FT PF01450 IlvC, Acetohydroxy acid isomeroreductase." FT /db_xref="GOA:O33114" FT /db_xref="HSSP:1NP3" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/Swiss-Prot:O33114" FT /protein_id="CAC30647.1" FT /translation="MFYDDNADLSIIQRRKVGVIGYGSQGYAHSLSLRDSGVQVRVGLP FT EGSKSRPKAFEQGLDVDTPAEVAKWADVIMLLVPDTAQADVFENDIEPNLQPGDALFFG FT HGLNIHFELVKPSGDVTVAMVAPKGPGYLVRRQFVDGKGVPCLIAVNQDPTGTGEALAL FT SYAKAIGGTRAGVIKTTFKDETETDLFGEQAVLCGGTEELVKAGFDVMVEAGYPPEMAY FT FEVLHELKLIVDLMYEGGIARMNYSVSDTAEFGGYLSGPRVIDADTKERMRGILRDIQD FT GSFVKKLVANVEGGNKQLEVLRKENAEHPIEVTGKKLRDLMSWVDRQSTETA" FT misc_feature complement(43797..44771) FT /note="Pfam match to entry PF01450 IlvC, Acetohydroxy acid FT isomeroreductase, score 716.00, E-value 1.8e-211" FT CDS complement(44824..45333) FT /transl_table=11 FT /gene="ilvN" FT /gene_synonym="ML1695" FT /product="acetolactate synthase I small subunit" FT /note="Highly similar to many acetolactate synthases, small FT subunit, (EC 4.1.3.18) involved in valine and isoleucine FT biosynthesis, including: Mycobacterium avium SW:ILVH_MYCAV FT (Q59499) (167 aa); Fasta score E(): 0, 78.9% identity in FT 166 aa overlap and Mycobacterium tuberculosis RV3002C FT SW:ILVH_MYCTU (O53249) (168 aa); Fasta score E(): 0, 83.5% FT identity in 164 aa overlap. Contains Pfam match to entry FT PF01842 ACT, ACT domain." FT /db_xref="GOA:O33113" FT /db_xref="InterPro:IPR002912" FT /db_xref="UniProtKB/Swiss-Prot:O33113" FT /protein_id="CAC30648.1" FT /translation="MVGLPTHTLSVLVEDTPGVLARVAALFSRRGFNIESLAVGATECK FT TMSRMTIVVSAEETPLEQVTKQLHKLINVIKVVEQEADNSLSRELALIKVRAEAGTRSQ FT VIEAVHLFRARVIDVSLESLTVEATGDCSKIEALLRVLEPFGVREIVQSGVVSLSRGPR FT GIGTVR" FT misc_feature complement(45094..45315) FT /note="Pfam match to entry PF01842 ACT, ACT domain, score FT 79.90, E-value 5.2e-20" FT CDS complement(45385..47262) FT /transl_table=11 FT /gene="ilvB" FT /gene_synonym="ML1696" FT /product="acetolactate synthase I large subunit" FT /note="Highly similar to many acetolactate synthases, large FT subunit, (EC 4.1.3.18) involved in valine and isoleucine FT biosynthesis, including: Mycobacterium avium SW:ILVB_MYCAV FT (Q59498) (621 aa); Fasta score E(): 0, 82.7% identity in FT 624 aa overlap and Mycobacterium tuberculosis RV3003C FT SW:ILVB_MYCTU (O53250) (618 aa); Fasta score E(): 0, 87.1% FT identity in 627 aa overlap. Contains Pfam match to entry FT PF00205 TPP_enzymes, Thiamine pyrophosphate enzymes. FT Contains PS00187 Thiamine pyrophosphate enzymes signature." FT /db_xref="GOA:O33112" FT /db_xref="HSSP:1N0H" FT /db_xref="InterPro:IPR012000" FT /db_xref="UniProtKB/Swiss-Prot:O33112" FT /protein_id="CAC30649.1" FT /translation="MSAPTKPHARPQGAGNSVPNTVKPATQFPSKPAVAKLERVSPEQL FT TGAQSVIRSLEELDVEVIFGIPGGAVLLVYDPLFYSKKLRHVLVRHEQGAGHAASGYAH FT VTGKVGVCMATSGPGATNLVTPLADAQMDSVPVVAITGQVGRSLIGTDAFQEADISGIT FT MPITKHNFLVRAGDDIPRVLAEAFHIASSGRPGAVLVDIPKDVLQGQCKFSWPPKMDLP FT GYKPNTKPHNRQIRAAAKLIADARKPVLYVGGGVIRGEATEQLRDLAELTGIPVVSTLM FT ARGAFPDSHHQNLGMPGMHGTVAAVAALQRSDLLIALGTRFDDRVTGKLDSFAPDAKVI FT HADIDPAEIGKNRHADVPIVGDVKAVIVELIAMLRHYEVPGNIEMTDWWSYLDGVRKTY FT PLSYSPQSDGTLSPEYVIEKLGEIVGPEAVYVAGVGQHQMWAAQFISYEKPRTWLNSGG FT LGTMGFAIPAAMGAKIARPEAEVWAIDGDGCFQMTNQELATCAIEGAPIKVALINNGNL FT GMVRQWQALFYQERYSQTDLATHSHRIPDFVKLAEALGCVGLRCECEEDVVDVINQARA FT INNRPVVIDFIVGADAQVWPMVAAGASNDEIQAARGIRPLFDDESEGHV" FT misc_feature complement(45505..47100) FT /note="Pfam match to entry PF00205 TPP_enzymes, Thiamine FT pyrophosphate enzymes, score 876.10, E-value 9.5e-272" FT misc_feature complement(45796..45855) FT /note="PS00187 Thiamine pyrophosphate enzymes signature" FT CDS 47629..47993 FT /pseudo FT /transl_table=11 FT /gene="ML1697" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3004 (Best blastx score 93)" FT CDS complement(48034..48867) FT /transl_table=11 FT /gene="ML1698" FT /product="conserved membrane protein" FT /note="Highly similar to Mycobacterium tuberculosis FT hypothetical protein RV3005C TR:O53252 (EMBL:AL021287) (279 FT aa); Fasta score E(): 0, 68.7% identity in 278 aa overlap. FT Contains possible membrane spanning hydrophobic domains." FT /db_xref="InterPro:IPR011637" FT /db_xref="UniProtKB/TrEMBL:O33110" FT /protein_id="CAC30651.1" FT /translation="MTGQSHDEHWRRPGECPEPIPGRPASASLVDPEDDLTPVGYPGDF FT GTTTVIPYSDPDHLKGPGGTGYNLLDQQEPLPYVQPQARHAVAEPTEIDSDQDNERLHT FT VGRRGTQHLGLLVLRVGLGVVLAAQGLHKLFGWWGGQGLTGFKNSLTQVGYQHADILAY FT VSAGGEAVAGVLLVLGLFAPVVAAGALAFLINGLLAAWPHSPLFSFFLPDGNEHQITLI FT VMDVTVILCGPGRYGLDAGRRWAYRPFIGSFIVLIAGIAAGIAVWVLLNGVNPLA" FT CDS 49110..50228 FT /transl_table=11 FT /gene="ML1699" FT /product="putative lipoprotein" FT /note="Highly similar to Mycobacterium tuberculosis FT hypothetical protein RV3006 TR:O53253 (EMBL:AL021287) (373 FT aa); Fasta score E(): 0, 87.1% identity in 373 aa overlap. FT Contains possible membrane spanning hydrophobic domains. FT ontains a possible N-terminal signal sequence and an FT appropriately positioned Prokaryotic membrane lipoprotein FT lipid attachment site. Contains PS00013 Prokaryotic FT membrane lipoprotein lipid attachment site." FT /db_xref="GOA:O33109" FT /db_xref="InterPro:IPR011042" FT /db_xref="UniProtKB/TrEMBL:O33109" FT /protein_id="CAC30652.1" FT /translation="MRIGRSVRSGFTALCAALLILSSCARFNNTQSQPFTTKPELRPQP FT SSIPPPPPLPLTPFPKQCPAPGVMQGCLESTSGLIMGIDNKTALVAERTTGAVKEISVS FT AEPKVKTVVSVDSSGDGGLMDIVLSPTYQQDRLMYAYISTPTDNRVIRVADGDIPKNIL FT TGIPKGAVGNTGALIFTSPTTLVVLTGDVDNPAMAADPKSLAGKLLRIEQPTTIGQAPP FT TTALSSIGSGGGLCTDPVDDSLYVTDRTPTADRLQRITKNSKVSTVWTWPDKPGVAGCA FT AMDGTVLVNLISPKLTVAVRLAPSTGAVTGEPDVVRKDTHVHAWALRMSPDGNVWGATI FT NKTAGDAEKLDDVVFPLFPRGGGFPRNNDDKT" FT misc_feature 49149..49181 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(51170..52699) FT /transl_table=11 FT /gene="gatB" FT /gene_synonym="ML1700" FT /product="glutamyl-tRNA(Gln) amidotransferase, subunit B" FT /note="Highly similar to many glutamyl-tRNA(Gln) FT amidotransferases (subunit B) including: Bacillus subtilis FT SW:GATB_BACSU (O30509) (269 aa); BlastP Expect 8.6 and FT Mycobacterium tuberculosis SW:GATB_MYCTU (O53256) (509 aa); FT Fasta score E(): 0, 88.4% identity in 509 aa overlap. FT Contains Pfam match to entry PF01162 PET112, PET112 family. FT Contains PS01234 PET112 family signature." FT /db_xref="GOA:O33107" FT /db_xref="InterPro:IPR017958" FT /db_xref="UniProtKB/Swiss-Prot:O33107" FT /protein_id="CAC30653.1" FT /translation="MTVVSGASKASGADLLDYDVVVARFDPVFGLEVHVELSTVTKMFC FT GCATTFGAEPNTQVCPVCLGLPGSLPVLNRAAVQSAIRIGLALNCEIVPWCRFARKNYF FT YPDVPKNYQISQYDEPIAINGYLEVPLEDDTTWRVEIERAHMEEDTGKLTHLGSETGRI FT YGATTSLIDYNRAGVPLIEIVTKPIEGAGVRAPQIARAYVKALQDLLRTLDVSDVRMDQ FT GSMRCDANVSLKPIGTVEFGTRSEIKNVNSLKSVEMAVRYEMQRQGAILVSGGRIAQET FT RHFHEDGYTSPGRAKETAQDYRYFPDPDLEPVAPSRELVEQLRQTIPELPWLSRKRIQQ FT EWGISDEVMRDLVNAGAVELVAATVKNGASSEQARAWWGNFLVQKANEANITLDELAIT FT PAQVAVVVALVDEGKLSIRLARQVVEGVLAGEGEPEQVMVDRDLALVRDDSVMQAAVDE FT ALAADPDVAEKIRGGKVAAAGAIVGAVMKTTRGQADAARVRELVLAICGQG" FT misc_feature complement(51176..52444) FT /note="Pfam match to entry PF01162 PET112, PET112 family, FT score 340.60, E-value 1.7e-98" FT misc_feature complement(52139..52186) FT /note="PS01234 PET112 family signature" FT RBS complement(52708..52711) FT CDS complement(53048..54079) FT /transl_table=11 FT /gene="pfkA" FT /gene_synonym="ML1701" FT /product="6-phosphofructokinase" FT /note="Highly similar to many 6-phosphofructokinases (EC FT 2.7.1.11) including: Streptomyces coelicolor SW:K6PF_STRCO FT (O08333) (342 aa); Fasta score E(): 0, 56.5% identity in FT 345 aa overlap and Mycobacterium tuberculosis RV3010C FT SW:K6PF_MYCTU (O53257) (343 aa); Fasta score E(): 0, 90.4% FT identity in 343 aa overlap. Contains 2 Pfam matches to FT entry PF00365 PFK, Phosphofructokinase. Contains PS00433 FT Phosphofructokinase signature." FT /db_xref="GOA:O33106" FT /db_xref="HSSP:3PFK" FT /db_xref="InterPro:IPR015912" FT /db_xref="UniProtKB/Swiss-Prot:O33106" FT /protein_id="CAC30654.1" FT /translation="MRIGILTGGGDCPGLNAVIRAIVRTCDARYGSSVVGFQDGWRGLL FT ENRRMQLCNDDRNDRLLAKGGTMLGTAHVHPDKLRAGLHQIKQTLDDNGIDVLIPIGGE FT GTLTAAHWLSQEDVPVVGVPKTIDNDIDCTDVTFGHDTALTVATEAIDRLHSTAESHQR FT VMLVEVMGRHAGWIALSSGLASGAHMTLIPEQPFDVEEVCCLVKRRFQRGDSHFICVVA FT EGAKPVPGSITLRQGGMDEFGHERFTGVAAQLGAEVEKRINKDVRVTVLGHVQRGGTPT FT AFDRVLATRFGVNAADASHAGEYGQMVSLRGQDIGRVPLEDAVRQLKLVPESRYDDAAA FT FFG" FT misc_feature complement(53177..53338) FT /note="Pfam match to entry PF00365 PFK, FT Phosphofructokinase, score 68.20, E-value 1.3e-24" FT misc_feature complement(53225..53281) FT /note="PS00433 Phosphofructokinase signature" FT misc_feature complement(53405..54076) FT /note="Pfam match to entry PF00365 PFK, FT Phosphofructokinase, score 234.30, E-value 1.9e-85" FT CDS complement(54167..55660) FT /transl_table=11 FT /gene="gatA" FT /gene_synonym="ML1702" FT /product="glutamyl-tRNA(Gln) amidotransferase, subunit A" FT /note="Highly similar to many glutamyl-tRNA(Gln) FT amidotransferases (subunit A) including: Bacillus subtilis FT SW:GATA_BACSU (O06491) (485 aa); Fasta score E(): 0, 50.8% FT identity in 476 aa overlap and Mycobacterium tuberculosis FT RV3011C SW:GATA_MYCTU (O53258) (494 aa); Fasta score E(): FT 0, 88.5% identity in 494 aa overlap. Contains Pfam match to FT entry PF01425 Amidase, Amidase. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:O33105" FT /db_xref="HSSP:1M21" FT /db_xref="InterPro:IPR004412" FT /db_xref="UniProtKB/Swiss-Prot:O33105" FT /protein_id="CAC30655.1" FT /translation="MIGSLHEIIRLDASTLAAKIVAKELSSVEITQACLDQIEATDDTY FT RAFLHVAAEKALSAAAAVDKAVAAGGQLSSTLAGVPLALKDVFTTVDMPTTCGSKILQG FT WHSPYDATVTTRLRAAGIPILGKTNMDEFAMGSSTENSAYGPTRNPWNVDRVPGGSGGG FT SAAALAAFQAPLAIGSDTGGSIRQPAALTATVGVKPTYGTVSRYGLVACASSLDQGGPC FT ARTVLDTALLHAVIAGHDARDSTSVEAAVPDIVGAAKAGESGDLHGVRVGVVRQLRGEG FT YQSGVLASFQAAVEQLIALGATVSEVDCPHFDYALAAYYLILPSEVSSNLARFDAMRYG FT LRVGDDGSRSAEEVIALTRAAGFGPEVKRRIMIGAYALSAGYYDSYYSQAQKVRTLIAR FT DLDKAYRSVDVLVSPATPTTAFSLGEKADDPLAMYLFDLCTLPLNLAGHCGMSVPSGLS FT SDDDLPVGLQIMAPALADDRLYRVGAAYEAARGPLPSAI" FT misc_feature complement(54221..55576) FT /note="Pfam match to entry PF01425 Amidase, Amidase, score FT 658.70, E-value 3e-194" FT misc_feature complement(55277..55300) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(55657..55956) FT /transl_table=11 FT /gene="gatC" FT /gene_synonym="ML1703" FT /product="glutamyl-tRNA(Gln) amidotransferase, subunit C" FT /note="Highly similar to many glutamyl-tRNA(Gln) FT amidotransferases (subunit C) including:Bacillus subtilis FT SW:GATC_BACSU (O06492) (96 aa); Fasta score E(): 6.9e-08, FT 37.9% identity in 95 aa overlap and Mycobacterium FT tuberculosis RV3012C SW:GATC_MYCTU (O53259) (99 aa); Fasta FT score E(): 3.1e-28, 74.7% identity in 99 aa overlap." FT /db_xref="GOA:O33104" FT /db_xref="InterPro:IPR003837" FT /db_xref="UniProtKB/Swiss-Prot:O33104" FT /protein_id="CAC30656.1" FT /translation="MSPISRDEVLHLARLTRLVLTDTELASFSSQLDVILAHVSQIQAV FT DVTGVEPTDNPLKYVNITRPDETVPCLTQQQALAEAPEAIYGRFVVPQILGDNK" FT CDS 56093..56791 FT /transl_table=11 FT /gene="ML1704" FT /product="conserved hypothetical protein" FT /note="Highly similar to Mycobacterium tuberculosis FT hypothetical protein RV3013 TR:O53260 (EMBL:AL021287) (218 FT aa); Fasta score E(): 0, 84.3% identity in 216 aa overlap." FT /db_xref="GOA:Q9CBR7" FT /db_xref="InterPro:IPR002912" FT /db_xref="UniProtKB/TrEMBL:Q9CBR7" FT /protein_id="CAC30657.1" FT /translation="MEMPLTQRYATVLAVPSYLLRIELADRPGSLGSLAVALGSVGGDI FT LSLDVVERSGGYAIDDLVIEVPSGAMPDKLITAFESLPGVRVDSVRPHSGLLEAHRELE FT LLDQVAAADDNASKLQVLADEAPKVLRVSWCTVLRSSQGKLLRLAASVGAPETRANSAP FT WLPIERAAPLDGTAEWVPQSLRDMNTTMIAAPLGDPHTAVVLGRPGPEFRPSEVARLGY FT LAGIVATMLR" FT CDS complement(56794..58878) FT /transl_table=11 FT /gene="ligA" FT /gene_synonym="ML1705" FT /product="DNA ligase" FT /note="Highly similar to many DNA ligases (EC 6.5.1.2) FT essential for DNA replication and repair, including: FT DNLJ_ECOLI and Mycobacterium tuberculosis RV3014C FT SW:DNLJ_MYCTU (O53261) (691 aa); Fasta score E(): 0, 84.7% FT identity in 687 aa overlap. Contains Pfam match to entry FT PF01653 DNA_ligase_N, NAD-dependent DNA ligase. Contains FT Pfam match to entry PF00533 BRCT, BRCA1 C Terminus (BRCT) FT domain. Contains PS01055 NAD-dependent DNA ligase signature FT 1." FT /db_xref="GOA:O33102" FT /db_xref="HSSP:1B04" FT /db_xref="InterPro:IPR004149" FT /db_xref="UniProtKB/Swiss-Prot:O33102" FT /protein_id="CAC30658.1" FT /translation="MSSPEADPIGPEVLQQWRKLTEEVREHQFRYYVRDAPIISDAEFD FT ALLDRLTVLEEQHPELCTPDSPTQLVGGAGFMTDFVATEHLERMFSLDNAFSGDELNAW FT VTRIRAEIGNDAHYLCELKIDGVALSLVYRDGRLTRATTRGDGRTGEDVTLNARTIEDV FT PERLTVSDIYPLPEVLEVRGEVFFRVVDFQALNTSLVEEGKNPFANPRNSAAGSLRQKD FT PAVTAHRKLRMICHGLGHIEGFRPATQHQAYLALRDWGLPVSEHTTLVNDIAGVQGCIA FT YWAEHRHEVDHEIDGIVVKIDEVTLQRRLGSTSRAPRWAIAYKYLPEEAQTKLLDIRVN FT VGRTGRVTPFAFMTPVKVAGSTVGQATLHNPSEVKRKGVLIGDTVVIRKAGDVIPEVLG FT PVVDLRDGSEREFVMPTTCPECGTTLAPEKEGDADIRCPNARSCPGQLRERVFHVASRS FT ALDIQGLGYEAGVALLAAQVITSEGDLFTLTEKALLRTELFRNKAGELSANGKRLLVNV FT DKAKTAPLWRVLVALSIRHVGPTAARALATEFGSVDAILAASPEQLAAVEGVGTTIAAA FT VTEWFTVDWHRVIVNKWRAAGVRMVDERDTSVLPTCEGLTIVVTGSLAGFSRDDAKEAI FT VARGGKVAGSVSKKIAYVVVGDLPGYKYDKAVELGVPILNEDGFRLLLEQGPPVQQVVD FT " FT misc_feature complement(56803..57060) FT /note="Pfam match to entry PF00533 BRCT, BRCA1 C Terminus FT (BRCT) domain, score 20.90, E-value 0.031" FT misc_feature complement(57502..58848) FT /note="Pfam match to entry PF01653 DNA_ligase_N, FT NAD-dependent DNA ligase, score 986.60, E-value 5.9e-293" FT misc_feature complement(58423..58512) FT /note="PS01055 NAD-dependent DNA ligase signature 1" FT CDS complement(58937..59950) FT /transl_table=11 FT /gene="ML1706" FT /product="conserved hypothetical protein" FT /note="Highly similar to proteins of undefined function FT from Streptomyces coelicolor TR:Q9Z586 (EMBL:AL035569) (331 FT aa); Fasta score E(): 0, 38.6% identity in 337 aa overlap FT and Mycobacterium tuberculosis RV3015C TR:O53262 FT (EMBL:AL021287) (337 aa); Fasta score E(): 0, 78.3% FT identity in 337 aa overlap." FT /db_xref="GOA:Q9CBR6" FT /db_xref="InterPro:IPR002629" FT /db_xref="UniProtKB/TrEMBL:Q9CBR6" FT /protein_id="CAC30659.1" FT /translation="MSVFATASGVGSWPGSSPYPAAKVVVGELAGALAHIVELPARGVG FT ADMLGRAGALLIDVAIDTVPRGYRIAARPGAVTRRAFSLLDEDMDAFEAAWEMAGLRGR FT GRVVKVQAPGPITLAAGLELANGHRAITDSCAVRDLAESLAEGVAAHRAALARRLDTQV FT VVQFDEVSLPAALGGLLTGVTAFSPVAPLDETLAATLFDSCVATVGADVLLHSCAAELP FT WNFLQRSAIRAVSVDVNVLRTGDLDGIAAFVESGRTVVLGVVPATAPQRLPSVEQVAAA FT VVGVTDRLGFGRSALRDRIGVSPACGLAGATPHWACTAIELARKTAEAFAQDPDAI" FT CDS complement(60866..61942) FT /transl_table=11 FT /gene="ML1707" FT /product="probable tRNA FT (5-methylaminomethyl-2-thiouridylate)-methyltransferase" FT /note="Highly similar to many proposed tRNA FT (5-methylaminomethyl-2-thiouridylate) -methyltransferases FT including: Escherichia coli SW:TRMU_ECOLI (P25745) (368 FT aa); Fasta score E(): 0, 35.6% identity in 362 aa overlap FT and Mycobacterium tuberculosis RV3024C SW:TRMU_MYCTU FT (O53271) (367 aa); Fasta score E(): 0, 85.2% identity in FT 357 aa overlap." FT /db_xref="GOA:O33099" FT /db_xref="InterPro:IPR018318" FT /db_xref="UniProtKB/Swiss-Prot:O33099" FT /protein_id="CAC30660.1" FT /translation="MKVLAAMSGGVDSSVAAARMVDAGHDVVGVHLALSTVSGTLRTGS FT RGCCSKEDVSDARRVADVLGIPFYVWDFAEKFQEDVIDNFVSAYARGETPNPCVQCNQR FT IKFSALSVRALMLGFDTVATGHYARLSGGRLRRAVDRGKDQSYVLAVLTAQQLRHAAFP FT IGDTLKRQVRAEAARRGLLVADKPDSHGICFIPSGNTRAFLSECIGIRRGSVVDADGTV FT LAEHDGVHGFTVGQRKGLGIVGPGPNGRPRYVTAIDADTATVYVGDAADLGVHTLIGRA FT PVFTAGAAPLGPVQCVVQIRAHGETAVAVVELIGDELFVRLCEPLRGVARGQTLVLYRL FT DPDGDEVLGSATIASMSA" FT CDS complement(61939..63171) FT /transl_table=11 FT /gene="ML1708" FT /product="putative aminotransferase" FT /note="Highly similar to many aminotransferases resembling FT NifS, a protein of unknown function located within many FT nitrogen fixation gene clusters e.g. Azotobacter vinelandii FT SW:NIFS_AZOVI (P05341) (402 aa); Fasta score E(): 0, 39.1% FT identity in 394 aa overlap. Also highly similar to FT Mycobacterium tuberculosis NifS-like protein RV3025C FT TR:O53272 (EMBL:AL021287) (393 aa); Fasta score E(): 0, FT 84.9% identity in 391 aa overlap. Contains Pfam match to FT entry PF00266 aminotran_5, Aminotransferases class-V." FT /note="Similar to ML0596" FT /db_xref="GOA:Q9CBR5" FT /db_xref="HSSP:1P3W" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/TrEMBL:Q9CBR5" FT /protein_id="CAC30661.1" FT /translation="MIRQAPIAGILKCVMAYLDHAATTPMHPAAIEAMTTALGTVGNAS FT SLHTSGRVARRRIEESRELIADKLAARPSEVIFTAGGTESDNLAVKGIYWARRDAQPCH FT RRIVTTEVEHHAVLDSVNWLVEHEGAEVTWLPTAADGSVSAFGLREALQQHNDVALVSV FT MWANNEVGTVMPVVELAAVAAEFGVPMHSDAIQAVGQLPVKFGVSGLSAMSVAAHKFGG FT PPGVGALLLRRDISCVPLLHGGGQERDIRSGTPGVASVVGMAAAAQIAVDGLEINSIRL FT QVLRDRLIEGVLATIDDVALNGARDRMRLPGNAHFIFRGCEGDVLLMLLDANGIECSTG FT SACTSGVPQPSHVLIAMGADPASARGSLRLSLGHNSVEVDVEEVLRVLPGAVDRARRAS FT LAAAGAGGVGV" FT misc_feature complement(62020..63096) FT /note="Pfam match to entry PF00266 aminotran_5, FT Aminotransferases class-V, score 224.20, E-value 1.9e-63" FT CDS complement(63192..63892) FT /pseudo FT /transl_table=11 FT /gene="ML1709" FT /product="some similarity to acyltransferase Q59601 FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3026c (Best blastx score 316)" FT CDS complement(64067..64764) FT /pseudo FT /transl_table=11 FT /gene="ML1710" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3027c (Best blastx score 295)" FT CDS complement(65125..66081) FT /transl_table=11 FT /gene="eftA" FT /gene_synonym="ML1711" FT /product="electron transfer flavoprotein [alpha] subunit" FT /note="Highly similar to many electron transfer FT flavoprotein alpha-subunits, including: Paracoccus FT denitrificans SW:ETFA_PARDE (P38974) (307 aa); Fasta score FT E(): 0, 43.3% identity in 307 aa overlap and Mycobacterium FT tuberculosis RV3028C SW:ETFA_MYCTU (O53275) (318 aa); Fasta FT score E(): 0, 89.3% identity in 318 aa overlap. Contains FT Pfam match to entry PF00766 ETF_alpha, Electron transfer FT flavoprotein alpha subunit. Contains PS00696 Electron FT transfer flavoprotein alpha-subunit signature." FT /db_xref="GOA:O33096" FT /db_xref="HSSP:1O97" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/Swiss-Prot:O33096" FT /protein_id="CAC30664.1" FT /translation="MAEALVLVEHTEGALKKVSAELITAARVLGEPAAVVVGTPGTSAP FT LVDGLKTAGAAKIYVAESDAADKYLITPVVDVLAALAESSAPAAVLLAATADGKEIGGR FT LAARIGSGLLVDVVDVREGAVGVHSVFGGVFIVEAQANGDTPVITVRAGAVEAQPAEGA FT GEQVSVEVPAPAENATKITARAPAVVDNRPDLTEATVVVSGGRGVGSADNFSVVEALAD FT SLGAAVGASRAAVDSGYYPGQFQIGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVA FT VNKDEEAPIFEIADFGVVGDLFKVAPQLTDGIKARKG" FT misc_feature complement(65233..65313) FT /note="PS00696 Electron transfer flavoprotein alpha-subunit FT signature" FT misc_feature complement(65251..66078) FT /note="Pfam match to entry PF00766 ETF_alpha, Electron FT transfer flavoprotein alpha subunit, score 434.20, E-value FT 1.2e-126" FT CDS complement(66130..66930) FT /transl_table=11 FT /gene="eftB" FT /gene_synonym="ML1712" FT /product="electron transfer flavoprotein [beta] subunit" FT /note="Highly similar to many electron transfer FT flavoprotein beta-subunits, including: Megasphaera elsdenii FT SW:ETFB_MEGEL (O85691) (270 aa); Fasta score E(): 1.5e-25, FT 36.1% identity in 274 aa overlap and Mycobacterium FT tuberculosis RV3029C SW:ETFB_MYCTU (O53276) (266 aa); Fasta FT score E(): 0, 95.1% identity in 266 aa overlap. Contains FT Pfam match to entry PF01012 ETF_beta, Electron transfer FT flavoprotein beta subunit." FT /db_xref="GOA:O33095" FT /db_xref="HSSP:1O95" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/Swiss-Prot:O33095" FT /protein_id="CAC30665.1" FT /translation="MTNIVVLIKQVPDTWSERKLTDGDFTLDREAADAVLDEINERAVE FT EALQIREKEAVDGIKGSVTVLTAGPERATEAIRKALSMGADKAVHLKDDGMHGSDVIQT FT GWALARALGTIEGTELVIAGNESTDGVGGVVPAIIAEYLGLPQLTHLRTISVEGGKITG FT ERETDEGVFTLEAVLPAVVSVNEKINEPRFPSFKGIMAAKKKEVTVLTLAEIGVEVDEV FT GLANAGSKVLVSTPKPAKTAGEKITDEGDGGNQIVQYLVAQKII" FT misc_feature complement(66163..66927) FT /note="Pfam match to entry PF01012 ETF_beta, Electron FT transfer flavoprotein beta subunit, score 397.40, E-value FT 1.3e-115" FT CDS 67158..68000 FT /transl_table=11 FT /gene="ML1713" FT /product="conserved hypothetical protein" FT /note="Highly similar to several proteins of unknown FT function including: Mycobacterium tuberculosis RV3030 FT TR:O53277 (EMBL:AL021287) (274 aa); Fasta score E(): 0, FT 78.2% identity in 280 aa overlap." FT /db_xref="GOA:O33094" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:O33094" FT /protein_id="CAC30666.1" FT /translation="MSAFVPDVPNRIPDDPSSIDSTAFHGMLTLTGERTIPDLDIENYW FT FRRHQVVYQWLAQRCTGCEVLEAGCGEGYGADLIVDVAYRVIAVDYDEATVAHVRSRYP FT RVQVMQANLIELPLADASVDVVVNFQVIEHLWNQAQFVSECARVLRPSGLLMVSTPNRI FT TFSPGRDTSINPFHTRELNADELTQLLITADFSEVAMYGLFHGPRLKEMDARHGGSIID FT AQIARAVSNAPWPPELVADVAAVTAADFDIIEASAGPEASDGRDVDESLDLIAIAVRR" FT CDS 67997..69565 FT /transl_table=11 FT /gene="ML1714" FT /product="conserved hypothetical protein" FT /note="Highly similar to several proteins of unknown FT function including: Mycobacterium tuberculosis hypothetical FT protein RV3031 TR:O53278 (EMBL:AL021287) (526 aa); Fasta FT score E(): 0, 86.3% identity in 526 aa overlap and FT Pyrococcus abyssi TR:Q9V0M7 (EMBL:AJ248285) (602 aa); Fasta FT score E(): 2.7e-22, 30.0% identity in 556 aa overlap." FT /db_xref="GOA:Q9CBR4" FT /db_xref="InterPro:IPR015293" FT /db_xref="UniProtKB/TrEMBL:Q9CBR4" FT /protein_id="CAC30667.1" FT /translation="MNTSANPVPGLFTLVLHTHLPWLAHHGRWPVGEEWLYQSWAAAYL FT PLLQVLHTLADENRHRLITLGVTPVVNAQLDDPYCLDGMHHWLANWRLRATEAASVRSG FT SESKPACAPQALRAFGARECIEAQRALEYFATLWRHGGSPLLRSLIDAGTVELLGGPLA FT HPFQPLIAPRLREFALHEGLDDAWLRLAHRPTGIWAPECAYAPGMEHDYSAAGITHFMV FT DGPSLHGDTALGRPVGDTAVVAFGRDLQVSYRVWSPKSGYPGHAAYRDFHTYDHLTGLK FT PARVTGCNVPSEAKAPYDPDHADKVVDAHVDDFVGVVRNRLFTESERIGRPAHVVAAFD FT TELFGHWWYEGPIWLQRVLRALPTAGVRVGTLSDALAGGFVGNTVTLPPSSWGSGKDWQ FT VWAGDKVADLVQLNNEVVDTALTTVDKVLAQTTSLDGLLPRNHVADQLLRETLLTVSSD FT WPFMVSKDSAADYARYRAHLHAHATREIAGALASGRRDTAAQLADGWNRADGLFGALDA FT RRLPR" FT CDS 69591..70907 FT /transl_table=11 FT /gene="ML1715" FT /product="putative transferase" FT /note="Highly similar to several proteins of undefined FT function including: Mycobacterium tuberculosis hypothetical FT protein RV3032 TR:O53279 (EMBL:AL021287) (414 aa); Fasta FT score E(): 0, 87.9% identity in 414 aa overlap. Also FT similar to a putative transferase from Streptomyces FT coelicolor TR:Q9Z5B7 (EMBL:AL035478) (406 aa); Fasta score FT E(): 2.8e-22, 30.1% identity in 415 aa overlap. Contains FT Pfam match to entry PF00534 Glycos_transf_1, Glycosyl FT transferases group 1." FT /db_xref="GOA:Q9CBR3" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q9CBR3" FT /protein_id="CAC30668.1" FT /translation="MFIQRHAVVRGIFGTFAPAEGTTLMKILIVSWEYPPVVIGGLGRH FT VHHLSTALAAAGHDVVVLSRRPSGTDPCTHPTSDEISEGVRVIAAAQDPHEFTFSNDMM FT AWTLAMGHAMIRTGLSLTRHSSDLPWRPDVVHAHDWLVAHPAITLAQFYDVPMVSTIHA FT TEAGRHSGWVSGALSRQVHAVESWLVRESDSLITCSASMCNEIIELFGPGLAEITVIRN FT GIDPARWPFAARRARTGPAELLYVGRLEYEKGVHDVIAALPRIRRSYPGTTLTIAGEGT FT QQDWLVDQARKYKVIKATRFVGHLNHNELLAALQRADAAVLPSHYEPFGLVALEAAAAG FT TPLVTSNIGGLGEAVINGQTGVSCPPRDIAELAAMVCTVLEDPDAAQQRALAARERLTS FT DFDWQTVAQQTAQVYLAAKRRERQPQPRLPIVEHALPDR" FT misc_feature 70266..70778 FT /note="Pfam match to entry PF00534 Glycos_transf_1, FT Glycosyl transferases group 1, score 174.40, E-value FT 1.9e-48" FT CDS 71100..72163 FT /pseudo FT /transl_table=11 FT /gene="ML1716" FT /product="unknown putative membrane protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1490 (Best blastx score 164)" FT CDS complement(72403..72696) FT /transl_table=11 FT /gene="ML1717" FT /product="doubtful CDS" FT /note="unknown function." FT /db_xref="UniProtKB/TrEMBL:Q9CBR2" FT /protein_id="CAC30670.1" FT /translation="MRNSLELVDQAFGVRDDHRQRRVVVQLQDAVDPGLKCMQTPACAL FT VPEVSPSSMNDNRGPRLVYYTVGGGDMDVANTGWWGLDTKWSVADDELTVVG" FT CDS 74527..75034 FT /pseudo FT /transl_table=11 FT /gene="ML1718" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2993c (Best blastx score 104)" FT CDS complement(75974..76711) FT /transl_table=11 FT /gene="ML1719" FT /product="conserved hypothetical protein" FT /note="The C-terminus of this protein is weakly similar to FT several including: Escherichia coli putative FT lipopolysaccharide biosynthesis O-acetyl transferase FT SW:WBBJ_ECOLI (P37750) (196 aa); Fasta score E(): 4.3e-09, FT 35.8% identity in 134 aa overlap. Also highly similar to FT Mycobacterium tuberculosis RV3034C TR:O53281 FT (EMBL:AL021287) (300 aa); Fasta score E(): 0, 90.6% FT identity in 244 aa overlap." FT /db_xref="GOA:Q9CBR1" FT /db_xref="UniProtKB/TrEMBL:Q9CBR1" FT /protein_id="CAC30672.1" FT /translation="MTTMWGAPLHRRWCGSRLRDPLQAKFLTLASLKWVLANRAYTPWY FT LVRYWRLLKFKLANPHIITRGMVFLGKGVEIHATPELAQLEIGRWVHIGDKNTIRAHEG FT SLRFGDKVVLGRDNVINCYLDIELGSSALMADWCYVCDFDHRMDDINIPIKDQGIVKSP FT VRIGPDTWMAAKVTVLRGTSVGRGCVLGAHAVVRGVIPDYSVAVGAPAKVVNNRKLSWE FT QSAAQRAELAAALADIERKKAAH" FT CDS 77151..78245 FT /transl_table=11 FT /gene="ML1720" FT /product="conserved hypothetical protein" FT /note="Highly similar to Mycobacterium tuberculosis FT hypothetical protein RV3035 TR:O53282 (EMBL:AL021287) (360 FT aa); Fasta score E(): 0, 75.8% identity in 363 aa overlap." FT /db_xref="InterPro:IPR002372" FT /db_xref="UniProtKB/TrEMBL:Q9CBR0" FT /protein_id="CAC30673.1" FT /translation="MAAGPALSARGYLAMNAQTQAGCSLMEWENNDNGRQRWCVRLVQG FT GGFGGPLFDGFENLYVGEPGTIFSFPMTQWTRWRQPVIGMPSTPRFLGNGQLLVTTHLG FT QVLVFDAHRGMVVGSPLDLVDGVNPTDPTRGLADCVSAQRGCPVASAPAYSPASQTVVL FT DIWQPGAPTAGLIGLKYHSRQTPLLARAWTSDAIGAGVLASPVLSADGSTVYVNGRDQH FT LWALHAANGKPKWSVPLEFLAQTPPTVTPQGLIVSGGGPDTRLAAFKDAGDHAQQIWRR FT DDLTPLSTSSLAGVSVGYTVVSSSPAADAPGMSLLAFDPRNGHTLNSYPLPAATGYPVG FT VSIANNRRVITVTSDGQLYSFAPT" FT CDS complement(78249..78947) FT /pseudo FT /transl_table=11 FT /gene="ML1721" FT /product="probable secreted protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3036c (Best blastx score 382)" FT CDS complement(79032..80697) FT /pseudo FT /transl_table=11 FT /gene="ML1722" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3037c (Best blastx score 298). Similarity to Rv3037 FT appears to have been intersected by the repeat element." FT repeat_region complement(79621..80446) FT /note="Dispersed repeat, RLEP, copy 28" FT CDS complement(80825..81808) FT /transl_table=11 FT /gene="ML1723" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT protein RV3038C TR:O53285 (EMBL:AL021287) (327 aa); Fasta FT score E(): 0, 80.7% identity in 327 aa overlap." FT /db_xref="GOA:Q9CBQ9" FT /db_xref="HSSP:1L3I" FT /db_xref="InterPro:IPR013216" FT /db_xref="UniProtKB/TrEMBL:Q9CBQ9" FT /protein_id="CAC30676.1" FT /translation="MTRSTEISANAVPNPHATAEQVAAARKDSKLAQVLYHDWEAENYD FT EKWSISYDQRCVDYVRHCFDAIVPDELFTELPYDCALELGCGTGFFLLNLIQSGVARRG FT SVTDLSPGMVKIATRNGQSLGLDINGRVADAEGIPYDDNTFDLVVGHAVLHHIPDVELS FT LREVLRVLKPGGRFVFAGEPTDVGNRYARVFADLTWKVTIRVVQLPGLSAWRRTQVEID FT ENSRAAALEWVVDLHTFEPKVLETMATNAGAVQVKTVTEEFTAAMLGWPLRTFESTMPP FT SKLGWGWARFAFTSWKTLSWVDANVWRRVIPKSWFYNIIITGVKPS" FT CDS complement(81841..82599) FT /transl_table=11 FT /gene="ML1724" FT /product="putative enoyl-CoA hydratase/isomerase" FT /note="Similar to several proposed enoyl-CoA hydratases (EC FT 4.2.1.17) including: Rhizobium meliloti SW:ECHH_RHIME FT (Q52995) (257 aa); Fasta score E(): 1.8e-19, 34.7% identity FT in 225 aa overlap, Clostridium acetobutylicum SW:CRT_CLOAB FT (P52046) (261 aa); Fasta score E(): 1.7e-17, 27.9% identity FT in 240 aa overlap and Mycobacterium tuberculosis RV3039C FT TR:O53286 (EMBL:AL021287) (254 aa); Fasta score E(): 0, FT 85.6% identity in 243 aa overlap. Contains Pfam match to FT entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family." FT /note="Similar to ML2402" FT /db_xref="GOA:Q9CBQ8" FT /db_xref="HSSP:1HZD" FT /db_xref="InterPro:IPR005829" FT /db_xref="UniProtKB/TrEMBL:Q9CBQ8" FT /protein_id="CAC30677.1" FT /translation="MSEFVNIVVSDGSQDAGLAILLLSRPPTNAMTRQFYREIAMAADE FT LGRRDDVAAVILFGGHDIFSAGDDMQELRTLTAVEAGVAAEVRRQAVDAVATIPKPTVA FT AITGYALGAGLTLALAADWRVSGDNVKFGATEILADLVPDGDGLARLTRVAGVSRAKDL FT VFSGRFFDAAEALALGLIDDMVAPDDVYDIAAAWARRFLDGLPHALAAAKAGINEVFDL FT EPAERIAAERRRYVEVFAAAQPSLLLGGCD" FT misc_feature complement(82042..82545) FT /note="Pfam match to entry PF00378 ECH, Enoyl-CoA FT hydratase/isomerase family, score 116.50, E-value 5.2e-31" FT CDS complement(82667..83507) FT /pseudo FT /transl_table=11 FT /gene="ML1725" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3040c (Best blastx score 838)" FT CDS complement(83471..84388) FT /transl_table=11 FT /gene="ML1726" FT /product="putative ABC transporter protein, ATP-binding FT component" FT /note="Highly similar to many putative ABC transport, FT ATP-binding proteins including:Streptomyces coelicolor FT TR:CAB76322 (EMBL:AL158060) (279 aa); Fasta score E(): 0, FT 44.4% identity in 277 aa overlap and Mycobacterium FT tuberculosis RV3041C TR:O53288 (EMBL:AL021287) (287 aa); FT Fasta score E(): 0, 83.4% identity in 289 aa overlap. FT Contains Pfam match to entry PF00005 ABC_tran, ABC FT transporter. Contains PS00017 ATP/GTP-binding site motif A FT (P-loop)." FT /db_xref="GOA:Q9CBQ7" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9CBQ7" FT /protein_id="CAC30679.1" FT /translation="MATWSRLPGNRRSIAVRHDVRVSQLGPETGSDAADPDLLIDFKDV FT SLRCEGRVLVGPLDWAVELDERWVIIGPNGAGKTSLLRIAAAADHPSTGVAYVLGERLG FT RIDISELRARIGLSSSVLTQRVPSNEVVRDLVVSAGYAVLGRWRERYEGVDYQRAVDML FT ESMGAEHLADRTFGTLSEGERKRVLIARALMTDPELLLLDEPAASLDLGAREELVSRLA FT DLAADAYAPALVLVTHHVEEVPPGFSHCLLLSEAKVVAAGLLSDVLTAENLSTAFGQSI FT ALDVIDGRYFARRVRARAAHRRQL" FT misc_feature complement(83621..84196) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 119.00, E-value 8.9e-32" FT misc_feature complement(84152..84175) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(84398..85633) FT /transl_table=11 FT /gene="ML1727" FT /product="putative phosphoserine phosphatase" FT /note="Similar in the C-terminus to many phosphoserine FT phosphatases (EC 3.1.3.3) including: Escherichia coli FT SW:SERB_ECOLI (P06862) (322 aa); Fasta score E(): 1.7e-29, FT 38.5% identity in 309 aa overlap and Mycobacterium FT tuberculosis RV3042C TR:O53289 (EMBL:AL021287) (409 aa); FT Fasta score E(): 0, 86.3% identity in 408 aa overlap. FT Contains Pfam match to entry PF00702 Hydrolase, haloacid FT dehalogenase-like hydrolase." FT /db_xref="GOA:Q9CBQ6" FT /db_xref="HSSP:1L7O" FT /db_xref="InterPro:IPR004469" FT /db_xref="UniProtKB/TrEMBL:Q9CBQ6" FT /protein_id="CAC30680.1" FT /translation="MNTPPKVSVLITVTGVDQPGVTSALFAVLSRHGGELLNVEQVVIR FT GRLTLGVLVLCPPEVAAYTALRDDVQAAIRRVGLDVTIERSDDLPIIREPSTHTIFVLG FT RPITARAFGAVAREVAALDVNIDVIRGISDYPVTGLELRVSAPLEAAGSLRTALNRVAT FT EEHVDVAVEGYGLARRIKRLIVFDVDSTLVQGEVIEMLAARAGAQGTVAAITEAAMRGE FT LDFAESLQQRVATLAGLPVTVVDEVANQLQLMPGARTTLRTLRRLGFRCGVVSGGFRRI FT IEPLAHELMLDFVAANELEIVDGILTGRVVGTIVDRPGKAKALRYFSEQAGVPMEQTVA FT VGDGANDIDMLTAAGLGIAFNAKPALRAVADASLSHPYLDTVLFVLGVTRGEIEAADAA FT DGGVRRVEIPPD" FT misc_feature complement(84542..85093) FT /note="Pfam match to entry PF00702 Hydrolase, haloacid FT dehalogenase-like hydrolase, score 15.00, E-value 0.00037" FT CDS complement(85673..87397) FT /transl_table=11 FT /gene="ML1728" FT /product="cytochrome C oxidase, polypeptide I" FT /note="Highly similar to many cytochrome C oxidases (EC FT 1.9.3.1) including: Bacillus firmus SW:COX1_BACFI (Q04440) FT (624 aa); Fasta score E(): 0, 51.9% identity in 522 aa FT overlap and Mycobacterium tuberculosis SW:COX1_MYCTU FT (O53290) (573 aa); Fasta score E(): 0, 95.4% identity in FT 566 aa overlap. Contains Pfam match to entry PF00115 COX1, FT Cytochrome C and Quinol oxidase polypeptide I. Contains FT PS00077 Heme-copper oxidase catalytic subunit." FT /db_xref="GOA:Q9CBQ5" FT /db_xref="HSSP:1FFT" FT /db_xref="InterPro:IPR014241" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBQ5" FT /protein_id="CAC30681.1" FT /translation="MTAEALSSGELKAIRPYPARTGPKGNLVYKLITTTDHKMIGIMYC FT VACFIFFFVGGLLALLMRTELAAPGLQFLSNEQFNQLFTMHGTIMLLFYATPIVFGFAN FT LVLPLQIGAPDVAFPRLNAFSFWLFLFGAAIGMAGFITPGGAADFGWTAYTPLTDAIHS FT PGVGGDLWIMGLIVAGLGTILGAVNMITTVVCLRAPGMTMFRMPIFTWNILVTSILVLI FT AFPLLTAALFGLAADRHLGAHIYDAANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEI FT FPVFSRKPIFGYTTLVYATLSIAALSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGIK FT FFNWVGTMWKGQLTFETPMLFSVGFAVTFLLGGLTGVLLASPPLDFHVTDSYFVVAHFH FT YVLFGTIVFSTFAGIYFWFPKMTGRLLDEQLGKLHFWLTFIGFHTTFLVQHWLGDMGMP FT RRYADYLPTDGFQGLNVVSTIGSFILGASMFPFVWNVFKSWRYGEVVTVDDPWGYGNSL FT EWATSCPPPRHNFTELPRIRSERPAFELHYPHMVERLRDEAYVGRRHAEELVEVSLH" FT misc_feature complement(85946..87310) FT /note="Pfam match to entry PF00115 COX1, Cytochrome C and FT Quinol oxidase polypeptide I, score 756.40, E-value FT 1.2e-223" FT misc_feature complement(86456..86620) FT /note="PS00077 Heme-copper oxidase catalytic subunit" FT RBS complement(87398..87405) FT CDS 87612..88706 FT /transl_table=11 FT /gene="fecB" FT /gene_synonym="ML1729" FT /product="putative FeIII-dicitrate transporter lipoprotein" FT /note="Highly similar to several proteins involved in iron FT transport including: Mycobacterium avium FecB precursor FT TR:AAF73189 (EMBL:AF151098) (364 aa); Fasta score E(): 0, FT 67.4% identity in 362 aa overlap and Mycobacterium FT tuberculosis RV3044 TR:O53291 (EMBL:AL021287) (359 aa); FT Fasta score E(): 0, 75.6% identity in 357 aa overlap. FT Contains a possible N-terminal signal sequence and an FT appropriately positioned Prokaryotic membrane lipoprotein FT lipid attachment site. Contains Pfam match to entry PF01497 FT Peripla_BP_2, Periplasmic binding protein. Contains PS00013 FT Prokaryotic membrane lipoprotein lipid attachment site." FT /db_xref="GOA:Q9CBQ4" FT /db_xref="InterPro:IPR002491" FT /db_xref="UniProtKB/TrEMBL:Q9CBQ4" FT /protein_id="CAC30682.1" FT /translation="MLPTRAIVTVAAAVIAVGSGCGSGQPGSKPSSPTRSLLTPTTQIA FT GATVIGNERRPDQACAPEPATVDPGPPTRPAHNVAGVKPDVVQVPAEAQRIVVLAGDQL FT DALCALGLQYRVAAAALPNDSVSQPSYLGKTVHGLPGVGTRRAPDLSAIAATQPDLILG FT SQELTPQLYPQLTAIAPTVFTAAAPGATWEDNLRGVGAATARNDAVETLINGFSQRATQ FT IGATHDATHYQVSIVQLTTNTMRVYGSNNFPARVLTAVGVDRPTSQRFTDQAYIQSGIT FT DADLAKEPDFSAVDADIIYVSCTSPAVAKRAATVLDSGPWRKLSANHDNRIFIVNDEVW FT QTGEGLIAARGIVDDLRWINAPIN" FT misc_feature 87642..87674 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT misc_feature 87888..88628 FT /note="Pfam match to entry PF01497 Peripla_BP_2, FT Periplasmic binding protein, score 193.50, E-value 3.2e-54" FT CDS 88966..90054 FT /transl_table=11 FT /gene="adhA" FT /gene_synonym="ML1730" FT /product="alcohol dehydrogenase" FT /note="Highly similar to many Prokaryotic and Eukaryotic FT dehydrogenases including: Mycobacterium tuberculosis RV3045 FT SW:ADH_MYCTU (P31975) (346 aa); Fasta score E(): 0, 85.8% FT identity in 346 aa overlap and Arabidopsis thaliana FT SW:CAD1_ARATH (P42734) (360 aa); Fasta score E(): 0, 48.8% FT identity in 344 aa overlap. Contains Pfam match to entry FT PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains FT PS00059 Zinc-containing alcohol dehydrogenases signature." FT /note="Similar to ML2053" FT /db_xref="GOA:Q9CBQ3" FT /db_xref="HSSP:1UUF" FT /db_xref="InterPro:IPR013154" FT /db_xref="UniProtKB/TrEMBL:Q9CBQ3" FT /protein_id="CAC30683.1" FT /translation="MKSHVSKHRRKRRLGAMTTVSAYAATSATEPLTKVTINRRAPGPH FT DVAIQIKFAGICHSDIHTVKAEWGQPNYPVVPGHEIAGVVTAVGTEVTKHKVGDRVGVG FT CMVGSCGECSSCLAGIEQYCKRGATFTYNSIGTDGQSTQGGYSQAIVVDENFVVHIPDA FT LPLDAAAPLLCAGITLYSPLRHWNAKPGTRLAIIGLGGLGHMGVKLGRKMGCEVTVLSQ FT SLKKMEDGLQLGASNYYATADPDTFRKLRGSFDLILNTVSANLDLGKYLNLLDVNGTLV FT ELGIPEHPMLVPAFALALMRRSLAGSNIGGITETQEMMNFSAEHSVTPEIELIEPDYIN FT EAYERVLASDVRYRFVINISSL" FT misc_feature 89035..90039 FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score 430.50, E-value 1.5e-125" FT misc_feature 89197..89241 FT /note="PS00059 Zinc-containing alcohol dehydrogenases FT signature" FT CDS complement(91663..92640) FT /transl_table=11 FT /gene="nrdF" FT /gene_synonym="ML1731" FT /product="ribonucleotide reductase small subunit" FT /note="Highly similar to many ribonucleoside-diphosphate FT reductase 2 beta chains (EC 1.17.4.1), involved in DNA FT replication, including: Escherichia coli SW:RIR4_ECOLI FT (P37146) (319 aa); Fasta score E(): 0, 71.6% identity in FT 320 aa overlap and Mycobacterium tuberculosis RV3048 FT TR:Q50549 (EMBL:AL021287) (324 aa); Fasta score E(): 0, FT 93.5% identity in 324 aa overlap. Contains Pfam match to FT entry PF00268 ribonuc_red, Ribonucleotide reductases. FT Contains PS00368 Ribonucleotide reductase small subunit FT signature." FT /db_xref="GOA:Q9CBQ2" FT /db_xref="HSSP:1KGN" FT /db_xref="InterPro:IPR000358" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBQ2" FT /protein_id="CAC30684.1" FT /translation="MLTGKMKLIDRVSAINWNWLQDDKDAEVWDRLTGNFWLPEKVPVS FT NDLPSWGTLTASEKQLTMRVFTGLTLLDTIQGTVGAVSLIPDALTPHEEAVYTNIAFME FT SVHAKSYSSIFSTLCSTAEIDEAFRWSEENNNLQRKAKIVMEYYRGDEPLKRKVASTLL FT ESFLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKFQRGLVLVDDARRA FT ELKEYTYELLFELYDNEVEYTQDLYDRVGLTEDVKKFLRYNANKALMNLGYEALFPRDE FT TDVNPAILSALSPNADENHDFFSGSGSSYVIGKAVVTEDEDWDF" FT misc_feature complement(91711..92532) FT /note="Pfam match to entry PF00268 ribonuc_red, FT Ribonucleotide reductases, score 271.30, E-value 1.5e-92" FT misc_feature complement(92284..92334) FT /note="PS00368 Ribonucleotide reductase small subunit FT signature" FT CDS complement(92803..94285) FT /pseudo FT /transl_table=11 FT /gene="ML1732" FT /product="Probable monooxygenase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3049c (Best blastx score 1312)" FT CDS complement(94500..95327) FT /transl_table=11 FT /gene="ML1733" FT /product="putative TetR-family transcriptional regulator" FT /note="Similar to Mycobacterium tuberculosis RV3050C FT TR:O53295 (EMBL:AL021287) (246 aa); Fasta score E(): 0, FT 86.6% identity in 238 aa overlap. Contains a probable FT helix-turn-helix motif at aa 79-100 (Score 1407, SD +3.98) FT Contains Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family." FT /db_xref="GOA:Q9CBQ1" FT /db_xref="InterPro:IPR012287" FT /db_xref="UniProtKB/TrEMBL:Q9CBQ1" FT /protein_id="CAC30686.1" FT /translation="MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVK FT IDARSERWREHRKKVRGEIVDAAFRALDRLGPEVSVREIAEEAGTAKPKIYRHFTDKSD FT LFEAIGIRLRDMLWAAIFPAIDLATDSAREIIRRSVDEYVSLVDKHPNVLRVFIQGRFS FT AQSEATVRTLDEGREITLTMAEMFNNELREMELNRAASELAAFAAFGSVASATEWWLGP FT EPDSPRRMPREQFVAHLTIIMMAVIVGTAETLGISMNPDRPIHDAVPLDRSAS" FT misc_feature complement(95001..95138) FT /note="Pfam match to entry PF00440 tetR, Bacterial FT regulatory proteins, tetR family, score 61.90, E-value FT 1.3e-14" FT CDS complement(95374..97455) FT /transl_table=11 FT /gene="nrdE" FT /gene_synonym="ML1734" FT /product="ribonucleoside diphosphate reductase [alpha] FT chain" FT /note="Highly similar to Mycobacterium tuberculosis FT ribonucleoside-diphosphate reductase alpha chain (EC FT 1.17.4.1) RV3051C SW:RIR1_MYCTU (P50640) (693 aa); Fasta FT score E(): 0, 93.2% identity in 693 aa overlap. Contains FT Pfam match to entry PF00317 ribonucleo_red, Ribonucleotide FT reductase. Contains PS00089 Ribonucleotide reductase large FT subunit signature." FT /db_xref="GOA:Q9CBQ0" FT /db_xref="InterPro:IPR013554" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBQ0" FT /protein_id="CAC30687.1" FT /translation="MLNLYDADGKIQFDKDVLAARQFFLQHVNQNTVFFHNQDEKLDYL FT IRENYYEREVLDQYSRNFVKSLLDRAYAKKFRFSTFLGAFKYYTSYTLKTFDGKRYLER FT LEDRVCMVALTLAAGDTGLAEKLVDEIIDGRFQPATPTFLNSGKKQRGEPVSCFLLRIE FT DNMESIGRSVNSALQLSKRGGGVALLLSNIREHGAPIKNIEHQSSGVIPIMKLLEDAFS FT YANQLGARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVIIPDITFELAKR FT NEDMYLFSSYDVERVYEVPFADISVTEKYYEMLDDARIRKTKIKAREFFQKLAELQFES FT GYPYVMFEDTVNRANPIEGKITHSNLCSEILQVSTPSLFNDDLSYAKVGKDISCNLGSL FT NIAKTMDSPDFAQTVEVAIRALTAVSDQTHIKSVPSIEQGNNDSHAIGLGQMNLHGYLS FT REGIFYGSEEGVDFTNIYFYTVLFHVLLASNSIAIERGTFFKGFERSKYASGEFFDKYI FT EQTWEPKTDKVRQLFAEAAIRIPTQNDWKRLKELVVAHGIYNQNLQAVPPTGSISYINH FT STSSIHPIVSKVEIRKEGKIGRVYYPAPYMTNDNLQYYQDAYEIGYQKIIDTYAAATQH FT VDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVEGCVSCTL" FT misc_feature complement(95440..97251) FT /note="Pfam match to entry PF00317 ribonucleo_red, FT Ribonucleotide reductase, score 717.40, E-value 1.5e-268" FT misc_feature complement(95755..95823) FT /note="PS00089 Ribonucleotide reductase large subunit FT signature" FT CDS complement(97540..97956) FT /transl_table=11 FT /gene="nrdI" FT /gene_synonym="ML1735" FT /product="NrdI-family protein" FT /note="Highly similar to many NrdI-family proteins, the FT function of which are unknown but thought to be involved FT with ribonucleoside reductase functioning, including: FT Escherichia coli SW:NRDI_ECOLI (Q47415) (136 aa); Fasta FT score E(): 2.7e-31, 59.3% identity in 135 aa overlap and FT Mycobacterium tuberculosis RV3052C SW:NRDI_MYCTU (P95107) FT (150 aa); Fasta score E(): 0, 79.7% identity in 138 aa FT overlap." FT /db_xref="InterPro:IPR004465" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBP9" FT /protein_id="CAC30688.1" FT /translation="MQAHNLVYFSSVSENTHRFVQKLGVPAMRIPLHSRIEVSDPYVLV FT LPTYGGGRTAPDLQAGGYVPKQVIAFLNNEYNRALICGVVAAGNTNFGAEFCYAGDVVA FT RKCGVPYLYRFELMGTEDDVTAVRAGLANLWKEH" FT RBS complement(97961..97966) FT CDS complement(97985..98227) FT /transl_table=11 FT /gene="nrdH" FT /gene_synonym="ML1736" FT /product="glutaredoxin electron transport component of FT NrdEF" FT /note="Highly similar to many glutaredoxin-like proteins FT involved in electron transport for the ribonucleotide FT reductase system NrdEF, including: Escherichia coli FT SW:NRDH_ECOLI (Q47414) (81 aa); Fasta score E(): 1.1e-11, FT 44.0% identity in 75 aa overlap and Mycobacterium FT tuberculosis RV3053C TR:P95106 (EMBL:Z83866) (79 aa); Fasta FT score E(): 7.7e-31, 91.1% identity in 79 aa overlap." FT /db_xref="GOA:Q9CBP8" FT /db_xref="HSSP:1H75" FT /db_xref="InterPro:IPR012335" FT /db_xref="UniProtKB/TrEMBL:Q9CBP8" FT /protein_id="CAC30689.1" FT /translation="MMNITVYTKPACVQCSATYKALDKQGIPYQTVDISLDSEARDYVM FT ALGYLQAPVVVAGNNHWSGFRPDRIKALAGAVLTA" FT CDS complement(98697..99209) FT /pseudo FT /transl_table=11 FT /gene="ML1737" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3054c (Best blastx score 267)" FT CDS 99372..99961 FT /pseudo FT /transl_table=11 FT /gene="ML1738" FT /product="putative transcriptional regulator (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3055 (Best blastx score 428)" FT CDS 99983..100991 FT /pseudo FT /transl_table=11 FT /gene="dinP" FT /gene_synonym="ML1739" FT /product="DNA-damage-inducible protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT dinP (Best blastx score 362)" FT CDS complement(101031..101969) FT /transl_table=11 FT /gene="ML1740" FT /product="possible short chain reductase" FT /note="Similar to several including: Thermotoga maritima FT 3-oxoacyl-[acyl-carrier protein] reductase SW:FABG_THEMA FT (Q9X248) (246 aa); Fasta score E(): 1.4e-18, 33.2% identity FT in 193 aa overlap and Mycobacterium tuberculosis possible FT ketoacyl reductase RV3057C TR:P95101 (EMBL:Z83866) (287 FT aa); Fasta score E(): 0, 81.8% identity in 280 aa overlap. FT Contains Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase. Contains PS00061 Short-chain FT dehydrogenases/reductases family signature." FT /db_xref="GOA:Q9CBP7" FT /db_xref="HSSP:1JTV" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9CBP7" FT /protein_id="CAC30693.1" FT /translation="MVKTAQYFVGKRCFVTGAASGIGRATALRLAAYGAELYLTDRHCD FT GLAQTVSEARALGAQVPEYRALDISDYDEVAAFGADIHARHPSMDIVMNIAGVSVWGTV FT DRLTHDQWSNVVAINLMGPIHIIETFVPAILAAGRGGHLVNVSSAAGLVALPWHAAYSA FT SKYGLRGLSEVLRFDLARYRIGVSVVVPGAVRTPLVDTIEIAGVDRQDPRFSRWVDRFR FT GHAVSAERAAEKILAGVAKNRYLIYTSHDIRVLYGFKRLAWWPYGVVMKQVNVVFTRAL FT RPSPATMRCVEPIKVGVYSQPRSGEGGKSGN" FT misc_feature complement(101379..101939) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 191.90, E-value 9.8e-54" FT misc_feature complement(101442..101528) FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT CDS complement(101979..102588) FT /pseudo FT /transl_table=11 FT /gene="ML1741" FT /product="putative transcriptional regulator (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3058c (Best blastx score 207)" FT CDS 102813..104188 FT /pseudo FT /transl_table=11 FT /gene="ML1742" FT /product="possible lanosterol 14-alpha-demethylases FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3059 (Best blastx score 393)" FT CDS complement(104854..105058) FT /pseudo FT /transl_table=11 FT /gene="PE" FT /gene_synonym="ML1743" FT /product="PE-family protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue PE FT (Best blastx score 79)" FT CDS complement(106066..106718) FT /pseudo FT /transl_table=11 FT /gene="ML1744" FT /product="transcriptional regulator (GntR family) FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3060c (Best blastx score 270)" FT CDS complement(107729..109896) FT /pseudo FT /transl_table=11 FT /gene="fadE22" FT /gene_synonym="ML1745" FT /product="acyl-CoA dehydrogenase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT fadE22 (Best blastx score 1078)" FT CDS complement(110225..110592) FT /pseudo FT /transl_table=11 FT /gene="ML1746" FT /product="short-chain alcohol dehydrogenase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1144 (Best blastx score 107)" FT CDS 110708..111177 FT /pseudo FT /transl_table=11 FT /gene="ligB" FT /gene_synonym="ML1747" FT /product="DNA ligase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT ligB (Best blastx score 120)" FT CDS 111160..112100 FT /pseudo FT /transl_table=11 FT /gene="cstA" FT /gene_synonym="ML1748" FT /product="starvation-induced stress response protein FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT cstA (Best blastx score 200)" FT repeat_region 114373..115633 FT /note="1261 bp repeat, 100% identical to FT complement(2207445..2208705)" FT CDS complement(114940..115554) FT /pseudo FT /transl_table=11 FT /gene="ML1749" FT /note="Possible transposase pseudogene which is similar to FT Mycobacterium smegmatis putative IS1549 transposase FT TR:070063." FT repeat_region complement(115661..115681) FT /note="21 bp sequence found at 3'-ends of copies 2, 3, 4 FT and 6 of LEPREP" FT repeat_region complement(115682..115975) FT /note="Dispersed repeat, LEPREP, copy 4, truncated at FT 5'-end" FT CDS complement(116171..118042) FT /transl_table=11 FT /gene="ML1750" FT /product="conserved hypothetical protein" FT /note="The C-terminus of this protein is highly similar to FT many including several hypothetical proteins and putative FT phosphodiesterases e.g. Mycobacterium tuberculosis RV1354C FT SW:YD54_MYCTU (Q11024) (623 aa); Fasta score E(): 0, 63.3% FT identity in 605 aa overlap and Streptomyces coelicolor FT TR:Q9Z584 (EMBL:AL035569) (746 aa); Fasta score E(): 0, FT 40.0% identity in 455 aa overlap. Contains Pfam match to FT entry PF00990 DUF9, Domain of unknown function. Contains FT Pfam match to entry PF00563 DUF2, Domain of unknown FT function 2. Contains Pfam match to entry PF01590 GAF, GAF FT domain." FT /note="The C-terminus of the predicted product of this CDS FT is similar to ML1752" FT /db_xref="InterPro:IPR001633" FT /db_xref="UniProtKB/TrEMBL:Q9CBP6" FT /protein_id="CAC30703.1" FT /translation="MTRSLDELVTRVASKLMAATAATAVTISEGVLAILVEHFGVDVSF FT LRHNNHDIHATKLIVEWPPRDYVPDPDPIGVVYFADADPVFAMAEYLKEPAVLRPEPAN FT ADYQRRIEEGASVPAVSLACVPLLSGEITTGVLGFVKYGDREWHDDELRALQAIATLFA FT QLQARIVAEEQLRYLAEHDDLTGLLNRRALIAHLDERLADGQRGPVTLLFLGLDRLKAV FT NDYLGHNAGDRLIEVFADRLREAAESLTVIARFGGDEFVVVPAESVSVDVAESFAHRLQ FT TRLQKQVVIDGEILTRTVSIGVATGLPGRDTTSDLLRWADHAALSAKSDGSKVVVLDHG FT ISAQHTLRTEVELHLAGMIDTDLVLHYLPEVDMSTGKVLGTEALVRWQHPTRGLLFPDS FT FIPVAESINLAGKLGRMVMHSACAEFSRWRSAGVGLDALLRINVSPVQLVAEGFVDNVA FT GTLDEFGLDGSMVCLEITENVVVQNIDATRKTLAGLKEVGVHLAIDDFGTGYSVLTHLK FT SLPVDTIKIDKSFVAELGSNASDLAIVRAIMALAKEFELEVVAEGVETAVAAQVLLELG FT CNRAQGFLLSRPVDGAAMESLLAKGVIPMALGTCQSPEPSEHQIHRS" FT misc_feature complement(116264..117004) FT /note="Pfam match to entry PF00563 DUF2, Domain of unknown FT function 2, score 321.50, E-value 9.5e-93" FT misc_feature complement(117044..117529) FT /note="Pfam match to entry PF00990 DUF9, Domain of unknown FT function, score 155.50, E-value 9.4e-43" FT misc_feature complement(117530..117976) FT /note="Pfam match to entry PF01590 GAF, GAF domain, score FT 57.90, E-value 2.2e-13" FT CDS complement(118060..120225) FT /transl_table=11 FT /gene="ML1751" FT /product="conserved hypothetical protein" FT /note="Similar to several proteins of undefined function FT e.g. Mycobacterium tuberculosis SW:YD55_MYCTU (Q11025) (715 FT aa); Fasta score E(): 0, 57.3% identity in 705 aa overlap. FT Contains Pfam match to entry PF00899 ThiF_family, ThiF FT family." FT /db_xref="GOA:Q9CBP5" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9CBP5" FT /protein_id="CAC30704.1" FT /translation="MAYGCNPRGAARVSDERDVSPYARVLALDDPADAAVLQRLRADSK FT VDFVDHHERQLQELLSLLPTPDPQLIAEPCRWVYYPWRHVVVSMLGPRGFRAVRLDRNR FT NEITAEEQVALGRLHIGVAGLSVGHVIAHTLAAQGLCGQLRLADFDRLELSNLNRVPAT FT VFDLGLNKAEVAARRIAELDPYLTVRVFDNGLTFDTVDQFLEGLDVVVEQCDSLDIKAL FT LREGARSHGIPVLMATSDRGLIDVERFDLEPRRSILHGLLGELDIRLLPEMSNREKIPY FT ILRFLEAERLSPRTATTLVEIDRSLSTWPQLAGDVALGATAVAEAVRRIGLGEELRSGR FT ARIDVASALNQLTEPDMARHRPANPTQCSELALSGIEGVIATAAIRAPSGGNLQPWHID FT AGPDALVIRIAPEHTDSLDVGFRGSAVAVGAALFNARVAAAAHGVLGPVSLAENVDGAP FT LRVTLSLGDGWNPDLAAVYEPMLVRETNRNHGKPTMVLTETIDVLHAAAVAEGARLHLL FT TARDDIVRAATILAAADRSRYLTPRLHEEMISELRWPGDSFPDTGIDVRSLEMDWHQLA FT AFDVLRRTDVMELLAQWNVGAALGQDTHDRVVASSALAVISVPGHALADYARGGSAVEA FT IWVAAQRYGFAVQPISPVFLYAHSVDELHALSAQFADELGQLGKDFRSLARIPADNSLV FT LVLRLTVAGPASVRSRRSFERIRLLSG" FT misc_feature complement(119467..119880) FT /note="Pfam match to entry PF00899 ThiF_family, ThiF FT family, score 113.20, E-value 4.9e-30" FT CDS complement(122369..123277) FT /transl_table=11 FT /gene="ML1752" FT /product="conserved hypothetical protein" FT /note="Similar to many including the C-terminus of several FT putative phosphodiesterases e.g. Streptomyces coelicolor FT TR:Q9Z584 (EMBL:AL035569) (746 aa); Fasta score E(): FT 2.5e-32, 38.4% identity in 305 aa overlap as well as FT several proteins of undefined function e.g. Mycobacterium FT tuberculosis RV1357C SW:YD57_MYCTU (Q11027) (307 aa); Fasta FT score E(): 0, 73.9% identity in 261 aa overlap. Contains FT Pfam match to entry PF00563 DUF2, Domain of unknown FT function 2." FT /note="Similar to the C-terminus of ML1750" FT /db_xref="InterPro:IPR001633" FT /db_xref="UniProtKB/TrEMBL:Q9CBP4" FT /protein_id="CAC30705.1" FT /translation="MPIEGAMRSSSLPDGCSDRSADSRGSGEVKDRSSGWFYGHHDREQ FT RSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFIS FT LAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVL FT GETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLP FT VDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDF FT GCDAAQGWHFAKALPADFFTE" FT misc_feature complement(122381..123145) FT /note="Pfam match to entry PF00563 DUF2, Domain of unknown FT function 2, score 404.00, E-value 1.5e-117" FT CDS complement(124818..128138) FT /transl_table=11 FT /gene="ML1753" FT /product="possible transcriptional regulator" FT /note="Highly similar to many from Mycobacterium FT tuberculosis e.g. probable transcriptional regulatory FT protein RV1358 TR:Q11028 (EMBL:Z75555) (1159 aa); Fasta FT score E(): 0, 58.1% identity in 1084 aa overlap. Contains a FT probable helix-turn-helix motif at aa 1063-1084 (Score FT 1080, SD +2.87) Contains Pfam match to entry PF00196 GerE, FT Bacterial regulatory proteins, luxR family. Contains FT PS00017 ATP/GTP-binding site motif A (P-loop). Contains FT PS00622 Bacterial regulatory proteins." FT /db_xref="GOA:Q9CBP3" FT /db_xref="HSSP:1FSE" FT /db_xref="InterPro:IPR000792" FT /db_xref="UniProtKB/TrEMBL:Q9CBP3" FT /protein_id="CAC30706.1" FT /translation="MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFL FT GDVEGLAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFARASDA FT TACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGLLDLACGGQTVLSS FT ITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLCHRNLRRNLHELGIRTVPGGPSL FT PVPLTTFVGRAAQIKELQELLTEKRLLTLVGPGGVGKTRLALQVVARVADEFSGELSYF FT DLAPDTDHDIFPITVLDNLRRCIGDRRMLMVLDNCEYLLDVCANVMTTLLGACPSLTIL FT ATSREPIGVAGEVIWRVSMLSPADEAVELFTERAALVQPGFSVTDGNRQIVTEICQRLD FT GMPLAIELAAARIRTLSLTEIADGLDDRFRLLTGGARTAVRRQQTLRASMDWSYALLTE FT SERALFRRLSAISGTFDLKVAYAVGHDDLEEPDQVFDRLTMLIDKSLVIVEGRQGGSRY FT RLLETVRQYAMKKLEESNEVDLVLARHRDHYMALGALLDTPGDIDHEQLVEQVETELDN FT LRSAFAWSRETGDIAGALQLASSLQPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEV FT LARAVANKVMLHAILASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYD FT TEVARPYFAEAVELARTQGDKWTLSQIRLWGVVGFCVSGDPVALRAAAEAADDLAQEIG FT DRFVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTFGLYVQTRALVHR FT DVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAAVEASEACRPHLGADH FT GLVAIHLELMAAVALARGDVIVARRLADNSVSATTGWHQMAALTTRARIAMAQGEPELA FT RADIHAALACGADIQASLGISDSMELLAELISQGDNHRQAGRLFGAASAQREKTGEVRF FT KVWDAGYESAVAVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESL FT TPAEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARHN" FT misc_feature complement(124821..125006) FT /note="Pfam match to entry PF00196 GerE, Bacterial FT regulatory proteins, luxR family, score 60.20, E-value FT 4.4e-14" FT misc_feature complement(124872..124955) FT /note="PS00622 Bacterial regulatory proteins" FT misc_feature complement(127359..127382) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 129473..129841 FT /pseudo FT /transl_table=11 FT /gene="ML1754" FT /product="PPE-family protein (pseudogene)" FT /note="Possible pseudogene similar to M. tuberculosis FT orthologue Rv1361c, PPE-family protein" FT CDS complement(130707..132083) FT /transl_table=11 FT /gene="sdaA" FT /gene_synonym="ML1755" FT /product="L-serine dehydratase" FT /note="Highly similar to many L-serine dehydratases (EC FT 4.2.1.13) including: Escherichia coli SW:TDCG_ECOLI FT (P42630) (454 aa); Fasta score E(): 0, 53.2% identity in FT 457 aa overlap and Mycobacterium tuberculosis RV0069 FT SW:SDHL_MYCTU (O53614) (461 aa); Fasta score E(): 0, 69.2% FT identity in 461 aa overlap." FT /db_xref="GOA:Q9CBP2" FT /db_xref="InterPro:IPR005131" FT /db_xref="UniProtKB/TrEMBL:Q9CBP2" FT /protein_id="CAC30708.1" FT /translation="MTISVFDLFTIGIGPSSSHTVGPMRAAARFVDGLAANGLLEDVCD FT IRVELFGSLAATGAGHGTMSAILLGLEGEHPERLDADDMVTRLACMRAAGTICLGGLIV FT IKFTEADVVLRPQTVLDRHPNAMTIVALARDGTKLAAETYYSVGGGFVVAHGDPPEGAE FT WTTGGVSFGSAGELLELAATRGMSICELMAEYEQSLRSEQEVRAGLLNIRDVMTQSVQR FT GIAQGGYLPGGLKVRRRAHSWHERLCAEDPNRDPVFAEDWVNLVALAVNEENAVGGRVV FT TAPTNGAAGIIPAVLHYAQHYCPAGRADPDDTSVRFLLTAGAIGSLYKELASISGAEVG FT CQGEVGSAASMAAAGLAEILGGTPAQVENAAEIAMEHSLGLTCDPIAGLVQIPCIERNA FT ISAGKAINAARMAMRGDGTHRVSLDEVIATMRATGRDMNFKYKETAAGGLALAVNIVEC FT " FT misc_feature 132341..132622 FT /note="Pfam match to entry PF00893 DUF7, Integral membrane FT protein, score 124.50, E-value 1.9e-33" FT CDS 132341..132664 FT /transl_table=11 FT /gene="ML1756" FT /product="probable multidrug resistance protein." FT /note="Highly similar to several multidrug resistance FT proteins e.g. Escherichia coli quaternary ammonium FT compound-resistance protein SW: QACE_ECOLI and FT Mycobacterium tuberculosis SW:YU65_MYCTU (P95094) (107 aa); FT Fasta score E(): 1e-31, 79.0% identity in 105 aa FT overlap.Contains multiple possible membrane spanning FT hydrophobic domains. Contains Pfam match to entry PF00893 FT DUF7, Integral membrane protein." FT /db_xref="GOA:Q9CBP1" FT /db_xref="HSSP:1S7B" FT /db_xref="InterPro:IPR000390" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBP1" FT /protein_id="CAC30709.1" FT /translation="MAYLFLFCAIFVEVVATTLLKSTEGFTRLVPTLACLAGYAVTFTL FT LALSISRGMKTDVAYALWSAIGTAAIVLIAVLFLDSPVSVAKVVGVALIIVGVITLNLA FT DAH" FT CDS 132661..133217 FT /pseudo FT /transl_table=11 FT /gene="ML1757" FT /product="putative transcriptional regulator (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3066 (Best blastx score 163)" FT CDS complement(133636..133979) FT /pseudo FT /transl_table=11 FT /gene="ML1758" FT /product="probable oxidoreductase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2776c (Best blastx score 219)" FT tRNA complement(134894..134969) FT /gene="alaU" FT /note="tRNA Ala anticodon GGC, Cove score 82.89" FT CDS complement(135040..136012) FT /pseudo FT /transl_table=11 FT /gene="pgmA" FT /gene_synonym="ML1759" FT /product="phosphoglucomutase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT pgmA (Best blastx score 432)" FT repeat_region complement(136010..136385) FT /note="Dispersed repeat, RLEP, copy 29" FT tRNA complement(136544..136617) FT /gene="metV" FT /note="tRNA Met anticodon CAT, Cove score 90.06" FT CDS complement(136652..136895) FT /pseudo FT /transl_table=11 FT /gene="ML1760" FT /product="integrase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2309c (Best blastx score 88)" FT CDS complement(137077..137421) FT /transl_table=11 FT /gene="ML1761" FT /product="hypothetical protein" FT /note="unknown function." FT /db_xref="UniProtKB/TrEMBL:Q9CBP0" FT /protein_id="CAC30714.1" FT /translation="MIEADYAAWLKERWEHFEHHTPLRVVNCPDYHLIRVAHELIAQVL FT NEHLDSKVTVLLFRRKYSPFLCQLLHDRTTDKMVRAVGLIRDAIALIMLDDIESRISRL FT VNSEGSSSAE" FT CDS complement(137929..138992) FT /pseudo FT /transl_table=11 FT /gene="ML1762" FT /product="possible transport protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2690c (Best blastx score 105)" FT CDS 139813..140028 FT /transl_table=11 FT /gene="ML1763" FT /product="hypothetical protein" FT /note="unknown function." FT /db_xref="UniProtKB/TrEMBL:Q9CBN9" FT /protein_id="CAC30716.1" FT /translation="MVARLASEVLRETVADDDRSSAIFDVAAPATSVFVETFLGRTTHP FT VGAAGIEFMALAPKQSRDVTLREIYH" FT CDS 140597..140923 FT /pseudo FT /transl_table=11 FT /gene="ML1764" FT /product="putative transport protein (pseudogene)" FT /note="Possible pseudogene fragment; similar to part of FT several trkA (potassium transport) genes e.g. SW:TRKA_METTH FT (O27333) (216 aa); Fasta score E(): 1.3, 33.8% identity in FT 71 aa overlap." FT CDS complement(141275..141677) FT /pseudo FT /transl_table=11 FT /gene="ML1765" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2313c (Best blastx score 125)" FT CDS complement(141770..142792) FT /pseudo FT /transl_table=11 FT /gene="ML1766" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2314c (Best blastx score 286)" FT CDS complement(142888..144263) FT /pseudo FT /transl_table=11 FT /gene="ML1767" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2315c (Best blastx score 309)" FT CDS 144326..145312 FT /transl_table=11 FT /gene="uspA" FT /gene_synonym="ML1768" FT /product="sugar transport integral membrane protein" FT /note="Similar to M. tuberculosis Rv2316 TR:P71896 FT (EMBL:Z79702) (290 aa); Fasta score E(): 0, 82.4% identity FT in 289 aa overlap probable sugar transport protein uspA, FT and to many others e.g. Thermococcus litoralis maltore FT transporter malF TR:O51924 (EMBL:AF012836) (300 aa); Fasta FT score E(): 4.7e-28, 33.6% identity in 283 aa overlap. FT Contains Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component." FT /note="Similar to ML1426, ML1087, ML1425 and ML1088" FT /db_xref="GOA:Q9CBN8" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9CBN8" FT /protein_id="CAC30721.1" FT /translation="MCAHFNTSMTNTGDDTEQSDEVGSISRLRGRKTHRTRALTKNHPR FT SIALAYALLAPSLFGVVTFLLLPIIVVIWLSLFRWDLLGPLHYVGLANWRSVLTDPNFA FT NSLIVTAVFVAIVVPTQTMLGLLIATMLARQLPGTGVFRTLYVLPWICAPLAIAVLWRW FT LLAPTDGAFSMVLRHRIEWLSDPSLALPVVSAVVVWTNVGYVSLSFLAGLLSIPEDINA FT AARTDGADAWQRFWRITLPMLRPTMFFVLVTGIVSTAQVFDTVYALTDGGPKSRTDLVA FT HRIYAEAFGSAAIGRASVMAVLLFVVLFGVTVVQHLYFQRRISYELT" FT misc_feature 144959..145192 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 51.90, E-value 1.4e-11" FT CDS 145299..146123 FT /transl_table=11 FT /gene="uspE" FT /gene_synonym="ML1769" FT /product="sugar transport integral membrane protein" FT /note="Similar to M. tuberculosis Rv2317 TR:P71895 FT (EMBL:Z79702) (274 aa); Fasta score E(): 0, 85.0% identity FT in 274 aa overlap probable sugar transport protein uspE, FT and to many others e.g. Thermomonospora fusca cellobiose FT transport permease bglB TR:AAF37729 (EMBL:AF086819) (305 FT aa); Fasta score E(): 1.9e-24, 30.2% identity in 275 aa FT overlap. Contains Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component." FT /note="Similar to ML1425 and ML1088" FT /db_xref="GOA:Q9CBN7" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9CBN7" FT /protein_id="CAC30722.1" FT /translation="MSSPSRLSNAVTYAGLTLGALITVAPFALGLLTSFTSAHQFTTGT FT PLQLPRPPTLANYAGLSGAGFLRATAVTALMTAVILLGQLTFSVLAGYAFARLRFPGRD FT TLFWAYIMTLMVPATVTVVPMYMMMAQVGLRNTFWALVLPFMFGSPYAIFLLREHFRII FT PNDLINAARLDGANTLDVIVHVVIPSNRSVLAALTLITVVSQWNNFMWPLVITSGNKWR FT VLTVATADLQSRFNAQWTLVMAATTVAIVPLIVLFVGFQRHIIPSIVVSGLK" FT misc_feature 145773..146003 FT /note="Pfam match to entry PF00528 BPD_transp, FT Binding-protein-dependent transport systems inner membrane FT component, score 47.50, E-value 2.9e-10" FT CDS 146215..147555 FT /transl_table=11 FT /gene="uspC" FT /gene_synonym="ML1770" FT /product="sugar transport periplasmic binding protein" FT /note="Similar to M. tuberculosis RV2318 TR:P71894 FT (EMBL:Z79702) (440 aa); Fasta score E(): 0, 74.7% identity FT in 446 aa overlap probable sugar transport periplasmic FT binding protein uspC and to many others e.g. FT Alicyclobacillus acidocaldarius maltose binding protein FT precursor TR:Q9RHZ6 (EMBL:AJ252161) (427 aa); Fasta score FT E(): 3.8e-05, 22.2% identity in 347 aa overlap. Contains FT probable signal sequence. Contains Pfam match to entry FT PF01547 SBP_bacterial_1, Bacterial extracellular FT solute-binding protein." FT /note="Similar to ML1427" FT /db_xref="GOA:Q9CBN6" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:Q9CBN6" FT /protein_id="CAC30723.1" FT /translation="MTRPRYSTLVAEALALATVLLTATAMLMGWSGGQLRGGKVVVTMR FT LWADQISTAYSQSFQAFTRTHPDIEVHTNVVAYSKYFNTLRTDVAGGSADDIFWLSSAY FT LAAYADNGRLINISNSLGQRATSDWEPAVVDQFTRAGALWGVPQLTDAGIAVFYNADLL FT TAAGIDPVQLNRMQWTSNDDDTLRPLLTQLTLDTNGHVAKTPGFDSRRVRQWGYNAAND FT PQAIYLNYIGSAGGVFQRGDEFAFDNPSAVEAFRYLVGLINNDHVAPPASETNNNGDFS FT RNQFLSGRMALFQSGTYNLALIAREARFHWGIAMMPTGPQGRVSVTNGIAVAGNSATKH FT PDAVRQVLAWMGSREGNAYLGRHGAAVPAVRSAQSVYFDYWAAKGIDVTPFFSVLDGPH FT IPAPGGAGFPAGDDALQSYFDEMFLGHGDVEKILCQAQAAANTAAHR" FT misc_feature 146632..147540 FT /note="Pfam match to entry PF01547 SBP_bacterial_1, FT Bacterial extracellular solute-binding protein, score FT 175.30, E-value 1e-48" FT CDS complement(147564..148386) FT /pseudo FT /transl_table=11 FT /gene="ML1771" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2319c (Best blastx score 252)" FT CDS complement(148463..149664) FT /pseudo FT /transl_table=11 FT /gene="rocE" FT /gene_synonym="ML1772" FT /product="arginine/ornithine transporter (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT rocE (Best blastx score 518)" FT CDS complement(149803..150274) FT /pseudo FT /transl_table=11 FT /gene="rocD2" FT /gene_synonym="ML1773" FT /product="ornithine aminotransferase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT rocD2 (Best blastx score 246)" FT CDS complement(150299..150919) FT /pseudo FT /transl_table=11 FT /gene="rocD1" FT /gene_synonym="ML1774" FT /product="ornithine aminotransferase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT rocD1 (Best blastx score 214)" FT CDS complement(150970..151587) FT /pseudo FT /transl_table=11 FT /gene="ML1775" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2323c (Best blastx score 122)" FT CDS 151679..152127 FT /pseudo FT /transl_table=11 FT /gene="ML1776" FT /product="transcriptional regulator (Lrp/AsnC family) FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2324 (Best blastx score 201)" FT repeat_region 153302..154119 FT /note="Dispersed repeat, RLEP, copy 30" FT CDS complement(154111..155542) FT /pseudo FT /transl_table=11 FT /gene="glpD1" FT /gene_synonym="ML1777" FT /product="glycerol-3-phosphate dehydrogenase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT glpD1 (Best blastx score 420)" FT CDS complement(155565..156203) FT /pseudo FT /transl_table=11 FT /gene="ML1778" FT /product="putative transcriptional regulator (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2250c (Best blastx score 307)" FT CDS 156482..157768 FT /pseudo FT /transl_table=11 FT /gene="ML1779" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2251 (Best blastx score 327)" FT CDS 157768..158709 FT /pseudo FT /transl_table=11 FT /gene="ML1780" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2252 (Best blastx score 590)" FT CDS complement(158723..159235) FT /transl_table=11 FT /gene="ML1781" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis Rv2256c TR:O53530 FT (EMBL:AL021925) (177 aa); Fasta score E(): 0, 93.5% FT identity in 170 aa overlap, and to other hypothetical FT preoteins e.g. TR:Q54209 (EMBL:L43074) (164 aa); Fasta FT score E(): 3.8e-27, 46.9% identity in 162 aa overlap FT unknown ORF downstream of Streptomyces glaucescens fabB." FT /db_xref="UniProtKB/TrEMBL:Q9CBN5" FT /protein_id="CAC30734.1" FT /translation="MRASNQFADATAGVVYVHASPAAVCPHVEWALSSTLQTKANLVWT FT PQPAMPGQLRAVTNWTGPVGTGARLANALRSWSVLRFEVTEDPSPGVDGQRFSHTPQLG FT LWSGSMSANGDIMVGEMRLRAMMAHGADTLAAELDSVLGTAWDDALEVYRDGGDVGEVT FT WLSRGVG" FT CDS complement(159374..160195) FT /transl_table=11 FT /gene="ML1782" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis Rv2257c TR:O53531 FT (EMBL:AL021925) (272 aa); Fasta score E(): 0, 76.4% FT identity in 271 aa overlap, and to Streptomyces coelicolor FT SC4A7.08 TR:Q9RDQ4 (EMBL:AL133423) (273 aa); Fasta score FT E(): 0, 53.2% identity in 269 aa overlap." FT /db_xref="InterPro:IPR001466" FT /db_xref="UniProtKB/TrEMBL:Q9CBN4" FT /protein_id="CAC30735.1" FT /translation="MVALDALDDWPVPTTAAAVVGPTGVLAARGDTEQVFPLASVTKPL FT VARAVQIAIEEGVVDLDTVAGPPGSTIRHLLAHASGLAMHSKYVMAPPGTRRIYSNYGF FT RVLAETVQREAGIGFSRYLTEAVLEPLAMTATKLEDGTWAAGFGATSTVADLAAFANDL FT LRPATVSAQIHAEATSVQFPDLDGVLPGHGVQRPNDWGLGYEIKNSKLPHWTGTLNSAR FT TYGHFGQSGGFIWADPEAELALVVLTDRDFGEWALQLWPAISDAVISEYAR" FT CDS complement(160195..161163) FT /transl_table=11 FT /gene="ML1783" FT /product="putative transcriptional regulator" FT /note="Similar to M. tuberculosis Rv2258c TR:O53532 FT (EMBL:AL021925) (353 aa); Fasta score E(): 0, 65.2% FT identity in 273 aa overlap but shorter at N-terminus and FT frameshifted near C-terminus. Also similar to some C. FT elegans proteins e.g. TR:O01593 (EMBL:U97004) (365 aa); FT Fasta score E(): 7.5e-17, 25.1% identity in 303 aa overlap. FT Contains a probable helix-turn-helix motif at aa 7-28 FT (Score 1191, SD +3.24)" FT /db_xref="InterPro:IPR013217" FT /db_xref="UniProtKB/TrEMBL:Q9CBN3" FT /protein_id="CAC30736.1" FT /translation="MVGLSLVTSTQIAYVAGLNERYVREWLGDMTTGHVVDYYAETGTY FT SLSVHRVAVLVWATGTNNLASVAQFIPLFSGFEQQFIGGFCDDVGGPYSEFPRFYSLMA FT EMSGAMFDAAFVDVVLPLANGLPERLRSGAGVADFDCGSGHVVNVLVRAFPASWFIGID FT FSNEAVAIHTAEEDRLGLGTVTFESHNLARLDKAAAYDVITVFDASHDHAQPVRVLENI FT YQALRPGDVLLMASIKVSSQLEDNVDVLMSIYLYTASLMHCMTVSLALQGAPDWMRCGE FT GGWPPRCSATRDWTTCGWSISSPTRSTTTYIYIATKLPRLT" FT CDS 161325..162410 FT /transl_table=11 FT /gene="adhE2" FT /gene_synonym="ML1784" FT /product="putative alcohol dehydrogenase (Zn dependent)" FT /note="Similar to M. tuberculosis adhE2 Rv2259 TR:O53533 FT (EMBL:AL021925) (361 aa); Fasta score E(): 0, 88.9% FT identity in 361 aa overlap, and to other alcohol FT dehydrogenases e.g. Amycolatopsis methanolica FT NAD/mycothiol-dependent formaldehyde dehydrogenase FT SW:FADH_AMYME (P80094) (360 aa); Fasta score E(): 0, 80.4% FT identity in 358 aa overlap. Contains Pfam match to entry FT PF00107 adh_zinc, Zinc-binding dehydrogenases. Contains FT PS00190 Cytochrome c family heme-binding site signature. FT Contains PS00059 Zinc-containing alcohol dehydrogenases FT signature." FT /note="Similar to ML1730 and ML2053" FT /db_xref="GOA:Q9CBN2" FT /db_xref="HSSP:1CDO" FT /db_xref="InterPro:IPR017816" FT /db_xref="UniProtKB/TrEMBL:Q9CBN2" FT /protein_id="CAC30737.1" FT /translation="MSQTVRGVISRKKDEPVELVDIVIPDPGPGEAVVDVTACGVCHTD FT LTYREGGINDRYPFLLGHEAAGTVEVVGPGVTAVEPGDFVILNWRAVCGQCRACKRGRP FT SYCFDTFNAQQKMTLIDGTELTPALGIGAFADKTLVHSGQCTKVDPAADPAVAGLLGCG FT VMAGLGAAINTAAVSRDDTVAVIGCGGVGDAAISGAALVGANRIIAVDIDDTKLEWART FT FGATHTVNALELEVVKTIQDLTSGFGVDVVIDTVGRPETWKQAFYARDLAGTVVLVGVP FT TPDMRLDMPLLDFFSHGGSLKSSWYGDCLPERDFPTLVDLYLQGRLPLGKFVSERIGLG FT DVEEAFHKIHGGKVLRSVVML" FT misc_feature 161343..162404 FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding FT dehydrogenases, score 293.40, E-value 2.9e-84" FT misc_feature 161439..161456 FT /note="PS00190 Cytochrome c family heme-binding site FT signature" FT misc_feature 161508..161552 FT /note="PS00059 Zinc-containing alcohol dehydrogenases FT signature" FT CDS 162407..162648 FT /pseudo FT /transl_table=11 FT /gene="ML1785" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2260 hypothetical protein Rv2260" FT repeat_region 162625..163049 FT /note="Dispersed repeat, REPLEP, copy 12, truncated at FT 5'-end" FT repeat_region 162625..163169 FT /note="REPLEP region 12, 3'-end most similar to REPLEP 7" FT repeat_region 163050..163087 FT /note="38 bp subsequence of 45 bp REPLEP associated FT sequence" FT repeat_region 163088..163169 FT /note="38 bp subsequence of 45 bp REPLEP associated FT sequence" FT CDS complement(163579..163880) FT /pseudo FT /transl_table=11 FT /gene="ML1786" FT /product="apolipoprotein N-acyltransferase-a (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2261c (Best blastx score 202)" FT CDS 164145..164430 FT /pseudo FT /transl_table=11 FT /gene="ML1787" FT /product="Probable cytochrome P-450 (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2266 (Best blastx score 246)" FT CDS complement(164405..164869) FT /transl_table=11 FT /gene="ML1788" FT /product="very hypothetical protein" FT /note="questionable CDS (possible pseudogene?)." FT /db_xref="UniProtKB/TrEMBL:Q7AQ24" FT /protein_id="CAC30741.1" FT /translation="MHDLSDSAAGPQSGPELGWAFQHQLSHAGQAQFNGQYQTGELGAH FT DDHLGMHYLPSFTTPFAQLLVLASMPQGLPQVLGTLYVENEKRRKLASTLRIRFLLAAD FT LPAIGQRRAHRQVSSTEPITLPISMFPWKTGVSANADIMLRGESRRPSDF" FT CDS 165194..165544 FT /pseudo FT /transl_table=11 FT /gene="ML1789" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2272 (Best blastx score 221)" FT CDS 165565..165863 FT /pseudo FT /transl_table=11 FT /gene="ML1790" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2273 (Best blastx score 80)" FT CDS complement(166670..167113) FT /transl_table=11 FT /gene="ML1791" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis hypothetical protein FT Rv1976c TR:O53977 (EMBL:AL022073) (135 aa); Fasta score FT E(): 3.5e-28, 65.3% identity in 124 aa overlap, and to FT Streptomyces coelicolor hypothetical protein SC1C3.03C FT TR:O69845 (EMBL:AL023702) (125 aa); Fasta score E(): FT 4.3e-06, 36.6% identity in 112 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9CBN1" FT /protein_id="CAC30744.1" FT /translation="MGKIFIMLPTVTHQAITCTVRRVRWIVDAMNVIGTRPDCWWKDRR FT GAMVRLVGKLERWASTERNHVTVVFERPPSPSIRSSVIVIAHAPKAFPDSADDEIVRLV FT QADPEPQGICVVTSDSALTDRVQEVGALAYPAARFRKHIDSID" FT CDS 167797..169386 FT /pseudo FT /transl_table=11 FT /gene="yjcE" FT /gene_synonym="ML1792" FT /product="probable Na+/H+ exchanger (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT yjcE (Best blastx score 885)" FT CDS 170063..170368 FT /transl_table=11 FT /gene="ML1793" FT /product="hypothetical protein" FT /note="unknown." FT /db_xref="UniProtKB/TrEMBL:Q9CBN0" FT /protein_id="CAC30746.1" FT /translation="MNATAPARPPQGDTRTPVLADDNSDLAAAIRRSSSQDSMSGDSPS FT RTHSMRATVSVVIHDGLFDLQLQQHEMLRAAELYDGTLRFLLWTAALFSALALSLI" FT CDS 172562..173770 FT /transl_table=11 FT /gene="ML1794" FT /product="aminotransferase" FT /note="Similar to M. tuberculosis predicted FT aminotransferase Rv2294 SW:YM94_MYCTU (Q50672) (407 aa); FT Fasta score E(): 0, 76.5% identity in 404 aa overlap, and FT to many others e.g. Escherichia coli MalY protein FT SW:MALY_ECOLI (P23256) (390 aa); Fasta score E(): 5.8e-27, FT 31.2% identity in 385 aa overlap." FT /note="Similar to and ML2502" FT /db_xref="GOA:Q9CBM9" FT /db_xref="HSSP:1GC0" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBM9" FT /protein_id="CAC30747.1" FT /translation="MTSNPLEQLTIEQLQCRTSMKWRAHPEDVLPLWVAEMDVLLAPTV FT AEAVHRAVDNGDTGYPYGTTFAEAISEFASQRWQWHDLDVSRTAIVPDVMLGVVEMLRL FT ITDRGDGVIVSPPVYPPFYAFVTHDGRRVLEAPLGRDGRLDLAALQDAFSRARRSSGPN FT GKVAYLLCNPHNPTGSVHTVAELHGVAELARRFGVRVISDEIHAPLVLSGARFTPYLSI FT PGAENAFALMSATKGWNLCGLKAAIAIAGREAAADLRRIPKEVSHGPSHLGIIAHTAAF FT RTGSSWLDALLQGLEANRALLRDLVTKHLPGVRYQRPQGTYLTWLDCRHLGFDEQINEG FT LAAISDLSGPARWFLDHSRVALTSGHAFGTGGVGHVRVNFATSQAILIEALSRMGRALV FT NFR" FT CDS 175347..175793 FT /transl_table=11 FT /gene="hsp18" FT /gene_synonym="ML1795" FT /product="18 KDA antigen (HSP 16.7)" FT /note="previously sequenced as SW:18KD_MYCLE (P12809) (148 FT aa); Fasta score E(): 0, 100.0% identity in 148 aa overlap; FT similar to other mycobacterial antigens e.g. Mycobacterium FT intracellulare SW:18K1_MYCIT (P46730) (149 aa); Fasta score FT E(): 0, 78.7% identity in 150 aa overlap, and small heat FT shock proteins e.g. Streptomyces albus hsp18 SW:HS18_STRAL FT (Q53595) (143 aa); Fasta score E(): 4.1e-26, 55.0% identity FT in 140 aa overlap. Contains Pfam match to entry PF00011 FT HSP20, Hsp20/alpha crystallin family." FT /db_xref="InterPro:IPR002068" FT /db_xref="UniProtKB/Swiss-Prot:P12809" FT /protein_id="CAC30748.1" FT /translation="MLMRTDPFRELDRFAEQVLGTSARPAVMPMDAWREGEEFVVEFDL FT PGIKADSLDIDIERNVVTVRAERPGVDPDREMLAAERPRGVFNRQLVLGENLDTERILA FT SYQEGVLKLSIPVAERAKPRKISVDRGNNGHQTINKTAHEIIDA" FT misc_feature 175419..175733 FT /note="Pfam match to entry PF00011 HSP20, Hsp20/alpha FT crystallin family, score 108.20, E-value 7.9e-29" FT CDS 176352..176765 FT /transl_table=11 FT /gene="ML1796" FT /product="hypothetical protein" FT /note="previously sequenced as SW:Y15K_MYCLE (P13733) (137 FT aa); Fasta score E(): 0, 100.0% identity in 137 aa FT overlap." FT /note="Similar to and" FT /db_xref="UniProtKB/Swiss-Prot:P13733" FT /protein_id="CAC30749.1" FT /translation="MSSLTTDLMLTHRHLNDRGQVAATIDEILNTHKLFSTRHRIIDTS FT ENVDNVIVIADQLFDDRGATIGTYDFYIDVSALPEQVHEGIVIARLAKSTQNRAGIEQT FT KSMLMLIDGITYDTPFNLLKYAVPGNQHQAAAG" FT CDS complement(177460..177828) FT /pseudo FT /transl_table=11 FT /gene="lipL" FT /gene_synonym="ML1797" FT /product="probable esterase (pseudogene)" FT /note="Possible pseudogene similar to M. tuberculosis FT orthologue lipL (Best blastx score 94)" FT CDS complement(177969..178952) FT /transl_table=11 FT /gene="ML1798" FT /product="putative kinase" FT /note="Similar to M. tuberculosis Rv1496 SW:YE96_MYCTU FT (P71777) (334 aa); Fasta score E(): 0, 83.0% identity in FT 323 aa overlap and to other members of the argK family e.g. FT SW:ARGK_ECOLI (P27254) (331 aa); Fasta score E(): 0, 44.9% FT identity in 321 aa overlap LAO/AO transport system kinase. FT Contains PS00017 ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q9CBM8" FT /db_xref="InterPro:IPR005129" FT /db_xref="UniProtKB/TrEMBL:Q9CBM8" FT /protein_id="CAC30751.1" FT /translation="MAGDSTVDRLVAAVRSGDRVALPRAITLVESTRSDHREQAQQLLL FT ALQPDAGNAHRVGITGVPGVGKSTAIEALGMHLIERGHRVAVLAVDPSSVRTGGSILGD FT KTRMARLAVHPDAYIRPSPTSGTLGGVTKATRETVVLLEAAGFDVILIETVGVGQSEVA FT VANMVDTFVLLALARTGDQLQGIKKGVLELADIVVVNKADGEHLRDARLAARDLSSALR FT LIYTHEKIWRPKVFTISATEGTGLTQMWEAVECHRQVLTASGEFENRRLAQQVEWAWQM FT VRDAVLDRVLSNPAVREIRAELECQVRAGELTPAMAAQQILQAASC" FT misc_feature complement(178749..178772) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(178953..181229) FT /transl_table=11 FT /gene="mutB" FT /gene_synonym="ML1799" FT /product="methylmalonyl-CoA mutase, [alpha] subunit" FT /note="Similar to M. tuberculosis mutB SW:MUTB_MYCTU FT (P71774) (750 aa); Fasta score E(): 0, 88.9% identity in FT 748 aa overlap, and many other methylmalonyl-CoA mutase FT alpha-subunit e.g. Streptomyces cinnamonensis SW:MUTB_STRCM FT (Q05065) (733 aa); Fasta score E(): 0, 74.7% identity in FT 726 aa overlap. Contains Pfam match to entry PF01642 FT MM_CoA_mutase, Methylmalonyl-CoA mutase. Contains PS00544 FT Methylmalonyl-CoA mutase signature." FT /note="Similar to and ML1800" FT /db_xref="GOA:Q9CBM7" FT /db_xref="HSSP:1REQ" FT /db_xref="InterPro:IPR006098" FT /db_xref="UniProtKB/TrEMBL:Q9CBM7" FT /protein_id="CAC30752.1" FT /translation="MTVRDVGGQQDRETTFVVGSFADIPLRSDRVVWPPSEAAVEKHVF FT SAASAHGYTVDQLHWHTPEGIDVKPVYIAADRAAAEAGGYPLHSFPGEPPYLRGPYPTM FT YVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLATHRGYDSDHPRVQGDVG FT MAGVAIDSILDMRQLFDGIDLSAVSVSMTMNGAVLPILALYVVAAEEQGVPPEKLAGTI FT QNDILKEFMVRNTYIYPPEPSMRIISDIFAYTSAKMPKFNSISISGYHIQEAGATADLE FT LAYTLADGVDYIKAGLDAGLDIDTFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAK FT FGPQSPKSLSLRTHSQTSGWSLTAQDPFNNVARTCIEAMAATQGHTQSLHTNALDEALA FT LPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHQLAARARTHIAEVAEHGG FT MAAAISDGIPKLRIEEAAARTQARIDSGRQPVVGVNKYQVDQDHEIEVLKVENSRVRAE FT QVAKLQQLRANRDQLAVDAALAELSGAAGAHGRAGDNLLALAINAARVQATVGEISDAL FT ERVYGRHQAKIRTITGVYRREVGEAGKATDIANATELVKKFAEADGRRPRILVAKMGQD FT GHDRGQKVVATAFADLGFDVDVGSLFSTPEEVARQAADNDVHVIGVSSLAAGHLTLVPA FT LRDALADVGRPDIMIVVGGVIPPDDFDELYAAGATAIFPPGTVIAYAAIGLLHKLAGRL FT GYTLT" FT misc_feature complement(179463..180929) FT /note="Pfam match to entry PF01642 MM_CoA_mutase, FT Methylmalonyl-CoA mutase, score 1090.80, E-value 0" FT misc_feature complement(179934..180011) FT /note="PS00544 Methylmalonyl-CoA mutase signature" FT CDS complement(181235..183145) FT /transl_table=11 FT /gene="mutA" FT /gene_synonym="ML1800" FT /product="methylmalonyl-CoA mutase, [beta] subunit" FT /note="Similar to M. tuberculosis mutA SW:MUTA_MYCTU FT (P71773) (615 aa); Fasta score E(): 0, 75.3% identity in FT 636 aa overlap, and many other methylmalonyl-CoA mutase FT beta-subunit e.g. Streptomyces cinnamonensis FT SW:SW:MUTA_STRCM (Q05064) (616 aa); Fasta score E(): 0, FT 42.7% identity in 626 aa overlap. Contains Pfam match to FT entry PF01642 MM_CoA_mutase, Methylmalonyl-CoA mutase. FT Contains PS00544 Methylmalonyl-CoA mutase signature." FT /note="Similar to and ML1799" FT /db_xref="GOA:Q9CBM6" FT /db_xref="HSSP:2REQ" FT /db_xref="InterPro:IPR004608" FT /db_xref="UniProtKB/TrEMBL:Q9CBM6" FT /protein_id="CAC30753.1" FT /translation="MFVDVPEFAELEQIRGRWRRAVAGVLSRSMRRDPATFGDQPERLL FT DTATYDGFAIRPLYTVFDELPESSLPGEWPYRRGGDALRDVHSGWKVTEVFPVDPATAG FT VAADEGTASNATILAALAEGVSALRIRVGQSGVAPGQLDSLLLGVYVDLVPVILDAGAD FT YVEACDAVLALLARLDSSRRTMLSIDLGADPLTASLSGRPAPSIDQVVAVAARVAGDRG FT VRAITVDGPAFHNLGASATWELAAAIAAAVTYLRVLTESKMPVSEALRQISFRLAADDD FT QFLTIAKIRAVRQLWARIAEVAGDPEGGAAVVHAETSLPMMTQRDPWVNMLRGTLAAFG FT AGVGGADTVLVFPFDVAIPGGFLGMAASFARRIARNTQLLLLEESHVGRVLDPAGGSWF FT VENLTEQLAQQAWQHFQAIETYGGFVDAGDYLAGQIHETAARRTDDIAHRRTAITGVNE FT YPNLAEPALLHGGSPVVATAAGNLLRYAAGFEALRDRSDAYLARTGARPQVLLLPLGPL FT AEHNIRATFATNLLASGGIAAINLGSVDAPGVVQAVAQAGFMAGSSMVVVICGTDLRYR FT DEAADVVEAARGAGVSWVYLAGPEKALGDINNAKSRPDEYITAKINAVEALSNLLTRLG FT A" FT misc_feature complement(181517..182971) FT /note="Pfam match to entry PF01642 MM_CoA_mutase, FT Methylmalonyl-CoA mutase, score 552.10, E-value 3.6e-162" FT misc_feature complement(181955..182032) FT /note="PS00544 Methylmalonyl-CoA mutase signature" FT CDS 183335..184020 FT /pseudo FT /transl_table=11 FT /gene="ML1801" FT /product="probable membrane protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1491c (Best blastx score 268)" FT CDS complement(184245..185369) FT /transl_table=11 FT /gene="ML1802" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis Rv1488 SW:YE88_MYCTU FT (P71768) (381 aa); Fasta score E(): 0, 89.8% identity in FT 373 aa overlap, and to many others members of the BAND 7 / FT MEC-2 family e.g. Streptomyces coelicolor conserved FT hypothetical protein SCI5.04C TR:Q9X9Z6 (EMBL:AL079332) FT (319 aa); Fasta score E(): 0, 54.7% identity in 311 aa FT overlap. Contains Pfam match to entry PF01145 Band_7, SPFH FT domain / Band 7 family. Contains PS00024 Hemopexin domain FT signature. Contains PS01270 Band 7 protein family FT signature." FT /db_xref="GOA:Q9CBM5" FT /db_xref="InterPro:IPR018080" FT /db_xref="UniProtKB/TrEMBL:Q9CBM5" FT /protein_id="CAC30755.1" FT /translation="MQGVVAGLVLLAVLTIFAIVVVAKSIVLIPQAEAAVVERLGRYGR FT TVSGQLTLLVLFIDRVRARVDLRERVVSFPPQPVITEDNLTLNIDTVVYFQVTVPQAAV FT YEISNYIVGVEQLTTTTLRNVVGGMTLEQTLTSRDQINAQLRGVLDEATGRWGLRVARV FT ELRSIDPPPSIQTSMEKQMKADREKRAMILTAEGTREAAIKQAEGNKQAQILAAEGAKQ FT AVILAAEADRQSRMLRAQGKRAAAYLQAQGQAKAIEKTFAAIKAGRPTPEMLAYQYLQI FT LPQMARGDANKVWVVPSDFSTALQGFTKLLGAPGEDGVFRFQPSPVDSSDQVVKHAADE FT DDAEVADWFSVETDPAIAQAVAKAEAMVYQPVDE" FT misc_feature complement(184458..184502) FT /note="PS00024 Hemopexin domain signature" FT misc_feature complement(184767..185339) FT /note="Pfam match to entry PF01145 Band_7, SPFH domain / FT Band 7 family, score 329.50, E-value 3.8e-95" FT misc_feature complement(184872..184958) FT /note="PS01270 Band 7 protein family signature" FT CDS complement(185406..185837) FT /transl_table=11 FT /gene="ML1803" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis Rv1487 TR:P71767 FT (EMBL:Z79701) (144 aa); Fasta score E(): 0, 74.8% identity FT in 143 aa overlap, and to many others e.g. Streptomyces FT coelicolor putative integral membrane protein SCI5.05C FT TR:Q9X9Z5 (EMBL:AL079332) (143 aa); Fasta score E(): FT 1.3e-12, 42.3% identity in 137 aa overlap." FT /db_xref="InterPro:IPR002810" FT /db_xref="UniProtKB/TrEMBL:Q9CBM4" FT /protein_id="CAC30756.1" FT /translation="MPVALVWLIFALVLACAEALTGDMFLLMLGGGALASAVSGWLTDW FT PIWVDGTVFLIVSVLLLTLVRPAVRRLTPALGTQLGIKALEGKAALVLDRVARNEGQVK FT LDGQVWTARTLSDDDVYEAGESVIVVHIDGATAMVFRNG" FT CDS 185895..186791 FT /transl_table=11 FT /gene="ML1804" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis Rv1486c SW:YE86_MYCTU FT (P71766) (302 aa); Fasta score E(): 5.1e-25, 76.7% identity FT in 300 aa overlap, and to Mycobacterium avium hypothetical FT protein MAV321 SW:YE86_MYCAV (O07402) (320 aa); Fasta score FT E(): 0, 62.9% identity in 315 aa overlap." FT /db_xref="UniProtKB/Swiss-Prot:Q9CBM3" FT /protein_id="CAC30757.1" FT /translation="MWCPSVSLSVWANAWLAGKAAPDDLLDALSLWTPMQSVAAYDAVA FT AGHTGLPWPDIHDAGTVSLLQTLRTAVGRPTKSTPNDPHRLRGTINVVLPVPGDVHGLV FT TGTQFEHDALAASEAVIITNPHDSSTAVGLVPEYSYSNPEQYTNSEETRLSELSALSWV FT VYSLPGVPLFDHHELGDAEYALRSAVRSAADALGTIELNSATADITDPRGLVEQLLESS FT RQHRVPDHAPSRALRVLENAAHVDAIISVSTGLTPIGTHSLSDIEIASNALRPLTAVVR FT SARMAAVNAILHSAWPD" FT CDS complement(186828..187838) FT /transl_table=11 FT /gene="hemZ" FT /gene_synonym="ML1805" FT /product="ferrochelatase" FT /note="Similar to M. tuberculosis hemZ SW:HEMZ_MYCTU FT (P71765) (344 aa); Fasta score E(): 0, 76.8% identity in FT 336 aa overlap, and to many others e.g. Propionibacterium FT freudenreichii shermanii ferrochelatase SW:HEMZ_PROFR FT (P72183) (352 aa); Fasta score E(): 0, 38.9% identity in FT 311 aa overlap. Contains Pfam match to entry PF00762 FT Ferrochelatase, Ferrochelatase. Contains PS00534 FT Ferrochelatase signature." FT /db_xref="GOA:Q9CBM2" FT /db_xref="HSSP:1DOZ" FT /db_xref="InterPro:IPR019772" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBM2" FT /protein_id="CAC30758.1" FT /translation="MLFDAALLLSFGGPDGPEQVRPFLENVTRGCNVPPERLDEVTKHY FT LHFGGVSPINGINLALVNELQVELDLPVYFGNRNWEPYIEDSVVTMRDDGIRCAAVFIT FT SAWSGYSSCTRYVEAIARARRRAGTGAPNLVKLRPYFDHPLFVEMFVDAITAAAASLPA FT ALRSEARLVFTAHSVPVATDRRCGPALYSRQVGYAARLVAAGAGYADYDLTWQSRSGPP FT YVPWLAPDVGDQLMTLASAGTKAVIVCPIGFVADHIEVVWDLDHELRSQADAAGVAFAR FT AATPNADRRFARLAASLIDELTHDRVPVRVNGSDPVPGCLASINGVPCDLPHCVA" FT misc_feature complement(186927..187820) FT /note="Pfam match to entry PF00762 Ferrochelatase, FT Ferrochelatase, score 92.30, E-value 9.9e-24" FT misc_feature complement(187266..187328) FT /note="PS00534 Ferrochelatase signature" FT CDS complement(187845..188654) FT /transl_table=11 FT /gene="inhA" FT /gene_synonym="ML1806" FT /product="enoyl-[ACP] reductase" FT /note="Similar to M. tuberculosis inhA Rv1484 SW:INHA_MYCTU FT (P46533) (269 aa); Fasta score E(): 0, 90.3% identity in FT 269 aa overlap, and to many others e.g. Escherichia coli FT enoyl-[acyl-carrier-protein] reductase [NADH] SW:FABI_ECOLI FT (P29132) (261 aa); Fasta score E(): 1.2e-17, 33.2% identity FT in 268 aa overlap." FT /note="Similar to and ML1807" FT /db_xref="GOA:Q9CBM1" FT /db_xref="InterPro:IPR016040" FT /db_xref="PDB:2NTV" FT /db_xref="UniProtKB/TrEMBL:Q9CBM1" FT /protein_id="CAC30759.1" FT /translation="MAGLLEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLR FT LIQRIADRLPDKAPLIELDVQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMG FT TNQFFDAPYEDVSKGIHISTYSYASLAKALLLIMNSGGSIVGMDFDPTRAMPAYNWMTV FT AKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGW FT DQRAPIGWNMKDPTPVAKTVCALLSEWLPATTGSIIYADGGASTQLL" FT CDS complement(188684..189445) FT /transl_table=11 FT /gene="fabG1" FT /gene_synonym="ML1807" FT /product="3-oxoacyl-[ACP] reductase (aka MabA)" FT /note="Similar to M. tuberculosis fabG Rv1483 SW:FABG_MYCTU FT (Q48930) (247 aa); Fasta score E(): 0, 68.6% identity in FT 245 aa overlap, and to many others e.g. Escherichia coli FT fabG 3-oxoacyl-[acyl-carrier protein] reductase FT SW:FABG_ECOLI (P25716) (244 aa); Fasta score E(): 0, 47.3% FT identity in 241 aa overlap. Contains Pfam match to entry FT PF00678 adh_short_C2, Short chain dehydrogenase/reductase FT C-terminus. Contains Pfam match to entry PF00106 adh_short, FT short chain dehydrogenase. Contains PS00061 Short-chain FT dehydrogenases/reductases family signature." FT /note="Similar to ML1806, ML2565, ML1740, ML1094, ML0862, FT ML0135, ML0135, ML0429, ML2357, ML0108 and ML2059" FT /db_xref="GOA:Q9CBM0" FT /db_xref="HSSP:1Q7B" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9CBM0" FT /protein_id="CAC30760.1" FT /translation="MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADG FT HRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVANAGITSDMLIM FT RMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRYIFMGSVVGLSGVPGQANYAASK FT SGLIGMARSLARELGSRSITANVVAPGFIDTEMTRAMDSKYQEAALQAIPLGRIGAVEE FT IAGAVSFLASEDAGYISGAVIPVDGGLGMGH" FT misc_feature complement(188711..188803) FT /note="Pfam match to entry PF00678 adh_short_C2, Short FT chain dehydrogenase/reductase C-terminus, score 51.30, FT E-value 6.7e-13" FT misc_feature complement(188861..189382) FT /note="Pfam match to entry PF00106 adh_short, short chain FT dehydrogenase, score 202.20, E-value 8e-57" FT misc_feature complement(188924..189010) FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature" FT CDS complement(189518..190525) FT /transl_table=11 FT /gene="ML1808" FT /product="possible membrane protein" FT /note="Similar to M. tuberculosis Rv1481 SW:YE81_MYCTU FT (P71762) (335 aa); Fasta score E(): 0, 91.0% identity in FT 335 aa overlap. Contains Pfam match to entry PF00092 vwa, FT von Willebrand factor type A domain." FT /note="Similar to and ML0701" FT /db_xref="GOA:Q9CBL9" FT /db_xref="InterPro:IPR002035" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBL9" FT /protein_id="CAC30761.1" FT /translation="MTLPLLGPMSLSGFEHSWFFLFIFIVFGLAAFYVMMQVARQRRML FT RFANMELLESVAPNRPVQWRHVPAILLMLALLLFTIAMAGPTNDVRIPRNRAVVMLVID FT VSQSMRATDVEPNRMAAAQEAAKQFAGELTPGINLGLIAYAGTATVLVSPTTNRYATKN FT ALDKLQFADRTATGEAIFTALQAIATVGAVIGGGEMPPPARIVLFSDGKETMPTNPDNP FT KGAYTAARTAKDQGVPISTISFGTVYGFVEINGQRQPVPVDDETMKKVAQLSGGNSYNA FT ATLAELKAVYASLQQQIGYETIKGDASAGWLRLGVLVLALAALTALLINRRLPT" FT misc_feature complement(189707..190231) FT /note="Pfam match to entry PF00092 vwa, von Willebrand FT factor type A domain, score -9.70, E-value 0.0049" FT CDS complement(190569..191531) FT /transl_table=11 FT /gene="ML1809" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis Rv1480 SW:YE80_MYCTU FT (P71761) (317 aa); Fasta score E(): 0, 87.5% identity in FT 311 aa overlap. Contains Pfam match to entry PF01882 DUF58, FT Protein of unknown function." FT /db_xref="InterPro:IPR002881" FT /db_xref="UniProtKB/TrEMBL:Q9CBL8" FT /protein_id="CAC30762.1" FT /translation="MIDPNPAAKPGVFHPPSMQRGQIDDPKLSAALRTLELTVKRKLDG FT VLHGDHLGLISGPGSEPGESRVYQPGDDVRRMDWAVTARTTHPHVRQMIADRELETWMV FT IDMSASLDFGTTICEKRDLAVAAAAAITFLNSGGGNRLGALICNGARMTRVPARSGRQH FT EQTLLRTIATTPKAPVGVRGDLTVAIDALRRPERRRGMAVIISDFLGPINWMRPLRAIA FT ARHEVLGIEVLDPRDVALPDIGEVVLQDAETGVTREFTIDAALRDDFARAAAAHCADVS FT RSLRNCGAPLMSLRTDRDWIADIVRFVESRRRGALAGRQ" FT misc_feature complement(190995..191510) FT /note="Pfam match to entry PF01882 DUF58, Protein of FT unknown function, score 169.50, E-value 5.4e-47" FT CDS complement(191528..192661) FT /transl_table=11 FT /gene="moxR" FT /gene_synonym="ML1810" FT /product="MoxR homolog" FT /note="Similar to M. tuberculosis moxR Rv1479 TR:O53170 FT (EMBL:AL021184) (377 aa); Fasta score E(): 0, 90.2% FT identity in 377 aa overlap, to many other moxR homologs and FT to e.g. Pyrococcus abyssi MOXR-3 TR:Q9UZ67 (EMBL:AJ248287) FT (314 aa); Fasta score E(): 0, 46.6% identity in 313 aa FT overlap. Contains Pfam match to entry PF01078 Mg_chelatase, FT Magnesium chelatase, subunit ChlI." FT /db_xref="GOA:Q9CBL7" FT /db_xref="InterPro:IPR016366" FT /db_xref="UniProtKB/TrEMBL:Q9CBL7" FT /protein_id="CAC30763.1" FT /translation="MTSAGGLPVGADGCSGPGGQSGPRAHEAPPGGADGLVAEVHTLER FT AIFEVKRVIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVGGTFARIQF FT TPDLVPTDIIGTRIYRQGKEEFDTELGPVVVNFLLADEINRAPAKVQSALLEVMQERHV FT SIGGKTFPLPNPFLVMATQNPIEHEGVYLLPEAQRDRFLFKINVGYPSPEEEREIIYRM FT GVTPPVPKQILNAGDLLRLQEISANNFVHHALVDYVVRVVTATRHPEQLGMNDVKTWIS FT FGASPRASLGIIKASRSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYNALADEISPEI FT VINRVLQTVALPQVNSFPQQGHSVPSVTQAAAAASGR" FT misc_feature complement(191612..192541) FT /note="Pfam match to entry PF01078 Mg_chelatase, Magnesium FT chelatase, subunit ChlI, score -20.80, E-value 3.2e-07" FT CDS complement(192896..193621) FT /transl_table=11 FT /gene="ML1811" FT /product="putative exported p60 protein homologue" FT /note="Similar to M. tuberculosis Rv1478 TR:O53169 FT (EMBL:AL021184) (241 aa); Fasta score E(): 0, 77.1% FT identity in 240 aa overlap, and to Listeria innocua protein FT p60 precursor (invasion-associated protein) SW:P60_LISIN FT (Q01836) (481 aa); Fasta score E(): 4.2e-07, 31.0% identity FT in 200 aa overlap. Contains Pfam match to entry PF00877 FT NLPC_P60, NLP/P60 family." FT /note="Similar to ML1812, ML1214 and ML0885" FT /db_xref="InterPro:IPR000064" FT /db_xref="UniProtKB/TrEMBL:Q9CBL6" FT /protein_id="CAC30764.1" FT /translation="MRHKNFRLINLAGLTAMVAGLIIVVTIPATADPGQWDPTLPAAVS FT AGAPGDPLAVANASLQVTAQATQTTLDLGKQFLGRLGINFGGDPSNAATTSSNPGGRIP FT RVYGGQAIEYVIKRGGAQIGVPYSWGGGSLQGPSKGVGDGANITGFDCSGLMRYAFAGV FT GVLIPRFSGDQYNAGRHLTPDQAKRGDLIFYGPGGGQHVTMYLGNGQMLEASSSVGKVT FT VSSVRKAGMTPFVTRIIES" FT misc_feature complement(192899..193267) FT /note="Pfam match to entry PF00877 NLPC_P60, NLP/P60 FT family, score 202.10, E-value 8.7e-57" FT CDS complement(193648..195087) FT /transl_table=11 FT /gene="ML1812" FT /product="putative exported p60 protein homologue" FT /note="Similar to M. tuberculosis Rv1477 TR:O53168 FT (EMBL:AL021184) (472 aa); Fasta score E(): 0, 78.8% FT identity in 480 aa overlap and to Listeria innocua protein FT p60 precursor (invasion-associated protein) SW:P60_LISMO FT (P21171) (484 aa); Fasta score E(): 1e-06, 23.8% identity FT in 491 aa overlap. Contains Pfam match to entry PF00877 FT NLPC_P60, NLP/P60 family." FT /note="Similar to ML1811, ML1214 and ML0885" FT /db_xref="InterPro:IPR000064" FT /db_xref="UniProtKB/TrEMBL:Q9CBL5" FT /protein_id="CAC30765.1" FT /translation="MKRPRRGSVSRPTARFVRPAIPSLVSAALLVSLPVLATADPDGDN FT LGTLIADVAKVNQRLEDLGAAIETEEQSVNKAMVSVEMARDNAVAAEHDCEVSQQSVKD FT ANTAINAAQHRFDSFAAATYMNGPSGSYLTATSPDDIIATATAARTLTASSQAVMANLQ FT RARTEQVNKESAARLAKQKADKAADDAKASMDAAVAALTASKRKFDEQRDEVNRLAAER FT DEAQARLEVAQIAAATWVPGMGGHGTPPFGDRWEPGSPASAGPAGGRKWDGWDPTLPQV FT PSANVPGDPIAVINQVLGYAATSTQVTASMGRNFLQQLGILKPNDTGITNAPIGSTQGR FT IPRVYGRQASEYVIRRGISQIGVPYSWGGGNAAGPSRGIDSGAGITGFDCSGLVLYSFA FT GVGIRLPHYSGSQYNLGRKIPSAQMRRGDVIFYGPGGSQHVTIYLGHGQMLEAPDIGLR FT VRVAPVRTSGMTPYVVRYIEY" FT misc_feature complement(193651..194019) FT /note="Pfam match to entry PF00877 NLPC_P60, NLP/P60 FT family, score 189.30, E-value 6.1e-53" FT CDS complement(195327..195899) FT /transl_table=11 FT /gene="ML1813" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis hypothetical protein FT Rv1476 TR:O53167 (EMBL:AL021184) (186 aa); Fasta score E(): FT 0, 78.7% identity in 178 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9CBL4" FT /protein_id="CAC30766.1" FT /translation="MTGQDVVVQQPQTIPMLPIYIPQDVDMTVVKSEVAAAGVSASPAA FT MPGLLEVVSHAQAEGINLKIVLLDHNLPNDTPLRDIATVVGADYPDVTVLTLSPNYVGS FT YSTHYPRVTLEAGEDISKTGNPVQSAQNFLGELNVPEFPWTVLTIVLLIGVLVAAIGTR FT FMQLRSKRLATSLDAAGILAEDVNRAD" FT CDS 196182..199016 FT /transl_table=11 FT /gene="acn" FT /gene_synonym="ML1814" FT /product="aconitate hydratase" FT /note="Similar to M. tuberculosis aconitate hydratase FT Rv1475c TR:O53166 (EMBL:AL021184) (943 aa); Fasta score FT E(): 0, 86.8% identity in 948 aa overlap, and to many FT others e.g. Bacillus subtilis aconitate hydratase FT SW:ACON_BACSU (P09339) (908 aa); Fasta score E(): 0, 51.1% FT identity in 940 aa overlap. Contains 2 Pfam matches to FT entry PF00330 aconitase, Aconitase family (aconitate FT hydratase). Contains Pfam match to entry PF00694 FT Aconitase_C, Aconitase C-terminal domain. Contains PS01244 FT Aconitase family signature 2. Contains PS00450 Aconitase FT family signature 1." FT /note="Similar to and ML1685" FT /db_xref="GOA:Q9CBL3" FT /db_xref="InterPro:IPR018136" FT /db_xref="UniProtKB/TrEMBL:Q9CBL3" FT /protein_id="CAC30767.1" FT /translation="MISSKDSVNSFSARDTLKIGDNSYQIYRLDAVSNTKRLPYSLKVL FT AENLLRNEDGKNITKDHIEAIANWDRQAEPSIEIQYTPARIVMQDFTGVPCIVDLATMR FT EAIGDLGGNPEKVNPLARVDLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWG FT QGAFNDFKVVPPGTGIVHQVNIEYLASVVMTQENTQGTVVAYPDTCVGTDSHTTMVNGL FT GVLGWGVGGIEAEAAMLGQPVSMLIPWVVGFKLSGEIQPGVTATDVVLTVTEMLRRHGV FT VGKFVEFYGEGVAEVPLANRATLGNMSPEFGSTAAIFPIDEETINYLRFTGRTPEQVAL FT VEGYAKEQGMWHDPKNEPTFSEYLELNLSDVVPSISGPKRPQDRICLAQAKSTFRAQIP FT KYVDGSSLHNQHSKLDEVVEETCPASDPGKLSFTNNDEVVMQSAAAHANGRVSNPVRIK FT TQELGEFVLDHGAVVIAAITSCTNTSNPEVMLCAALLARNAVEKGLASKPWVKTTMAPG FT SQVVNDYYDRSGLWPYLEKLGFYLVGYGCTTCIGNSGPLPEEISKAINYNNLSVTAVLS FT GNRNFEGRINPDVKMNYLASPPLVIAYALAGTMDFDFESQPLDTDKNGKAVYLKDIWPS FT QKDVTDTIASAINQEMFTKNYADVFKGDERWRNLPTPSGNTFDWEQNSTYVRKPPYFEG FT MSVEPKPVRNITGARVLALLDDSVTTDHISPASTIKPGTPAAQYLDTHGVDRKDYNSFG FT SRRGNHEVMIRGTFANIRLRNMLLNGVAGGYTRDFTKPGAPQAFIYDAAQNYAAENIPL FT VVLSGKEYGSGSSRDWAAKGTLLLGVRAVIAESFERIHRSNLIGMGVIPLQFPQGESAS FT SLGLDGTEVFEINGIDVFNNGKTPKTVHVKASKASGTTVTFDALVRIDTPGEADYYRNG FT GILHYVLRNILKSN" FT misc_feature 196350..197363 FT /note="Pfam match to entry PF00330 aconitase, Aconitase FT family (aconitate hydratase), score 504.40, E-value FT 1.5e-153" FT misc_feature 197571..198002 FT /note="Pfam match to entry PF00330 aconitase, Aconitase FT family (aconitate hydratase), score 220.10, E-value FT 1.3e-66" FT misc_feature 197595..197645 FT /note="PS00450 Aconitase family signature 1" FT misc_feature 197793..197834 FT /note="PS01244 Aconitase family signature 2" FT misc_feature 198384..198917 FT /note="Pfam match to entry PF00694 Aconitase_C, Aconitase FT C-terminal domain, score 199.70, E-value 4.7e-56" FT CDS 199031..199587 FT /pseudo FT /transl_table=11 FT /gene="ML1815" FT /product="transcriptional regulator (TetR/AcrR family) FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1474c (Best blastx score 442)" FT CDS complement(200005..201642) FT /transl_table=11 FT /gene="ML1816" FT /product="ABC transporter ATP-binding protein, possibly in FT EF-3 subfamily" FT /note="Similar to M. tuberculosis Rv1473 TR:O53164 FT (EMBL:AL021184) (542 aa); Fasta score E(): 0, 87.9% FT identity in 545 aa overlap, and to many others e.g. FT Haemophilus influenzae hypothetical ABC transporter FT ATP-binding protein SW:YHES_HAEIN (P44808) (638 aa); Fasta FT score E(): 1.4e-30, 31.5% identity in 518 aa overlap. FT Contains 2 Pfam matches to entry PF00005 ABC_tran, ABC FT transporter. Contains 2 x PS00017 ATP/GTP-binding site FT motif A (P-loop). Contains 2 x PS00211 ABC transporters FT family signature." FT /note="Similar to ML1248, ML0669, ML0848, ML2189, ML1122, FT ML0114 and ML0336" FT /db_xref="GOA:Q9CBL2" FT /db_xref="HSSP:1US8" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9CBL2" FT /protein_id="CAC30769.1" FT /translation="MITATDLEVRAGARILLSSDGPDLRVQPGDRIGLVGRNGAGKTTT FT LRILAGATEPYAGSVTWTGEIGYLPQDPKVGNLDVLARDRVLSARGLDVLLTDLEKQQA FT LMAEVADDDARDRAIRRYGQLEERFLALGGYSAESEAGRICASLGLPERVLVQQLCTLS FT GGQRRRVELARILFAASRAGTGASGSGTTLLLDEPTNHLDADSLGWLRDFLRSHTGGLV FT VISHNVELIAAVVNRVWFLDAVLGKVDVYNMGWYKYLDSRATDEQRRRRERVNAERKAT FT ALRTQAAKMGAKATKAVAAQNMLRRADRMMAALDEERVIEKVAQIKFPTPAACGRTPLV FT AKGLSKTYGSLEVFTGVNLAIDRGSRVVVLGLNGAGKTTLLRVLAGAEKPDVGRLEPGH FT GLRIGYFAQEHDTLDNEDTVWQNIRHTAPEFGEQDLRGLLGAFMFSGPQLDQLAGTLSG FT GEKTRLALAGLVASTANVLLLDEPTNNLDPASRKQVLDALRNYQGAVVLVTHDPGAAKA FT LDPQRVVLLPDGTEDYWSDEYRDLIELA" FT misc_feature complement(200056..200553) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 160.90, E-value 2.2e-44" FT misc_feature complement(200233..200277) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(200509..200532) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(200911..201558) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 143.50, E-value 3.8e-39" FT misc_feature complement(201115..201159) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(201514..201537) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(201679..202500) FT /pseudo FT /transl_table=11 FT /gene="echA12" FT /gene_synonym="ML1817" FT /product="enoyl-CoA hydratase/isomerase superfamily FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT echA12 (Best blastx score 581)" FT CDS complement(202571..202963) FT /transl_table=11 FT /gene="trxB" FT /gene_synonym="ML1818" FT /product="thioredoxin" FT /note="Similar to M. tuberculosis thioredoxin trxB Rv1471 FT TR:O53162 (EMBL:AL021184) (123 aa); Fasta score E(): FT 2.4e-25, 65.4% identity in 107 aa overlap, and M. FT tuberculosis thioredoxin trxA Rv1470 TR:O53161 FT (EMBL:AL021184) (124 aa); Fasta score E(): 1.6e-17, 47.0% FT identity in 117 aa overlap. Also similar to Escherichia FT coli thioredoxin 2 SW:THI2_ECOLI (P33636) (139 aa); Fasta FT score E(): 1.7e-07, 37.1% identity in 89 aa overlap. FT Contains Pfam match to entry PF00085 thiored, Thioredoxin." FT /note="Similar to and ML2703" FT /db_xref="GOA:Q9CBL1" FT /db_xref="HSSP:1NSW" FT /db_xref="InterPro:IPR013766" FT /db_xref="UniProtKB/TrEMBL:Q9CBL1" FT /protein_id="CAC30771.1" FT /translation="MVREHGVGVRRWTRRDLIAEQLNETINVNNMVLVAFWASWCGPDR FT LFVPTFHASSNKHSDVVHLNVDTKAERQLALAAQIRSIPTLVAFKKGKPLLSQAGDLTP FT AVPGYLVQQIKAFDVSDDGVVPDEQV" FT misc_feature complement(202682..202870) FT /note="Pfam match to entry PF00085 thiored, Thioredoxin, FT score 38.40, E-value 3e-10" FT CDS complement(202980..203337) FT /pseudo FT /transl_table=11 FT /gene="ctpD" FT /gene_synonym="ML1819" FT /product="cation-transporting ATPase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1469" FT CDS 204089..205056 FT /pseudo FT /transl_table=11 FT /gene="ML1820" FT /product="similar at C-term to adenylate cyclases FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv1319c (Best blastx score 265)" FT repeat_region 205033..205616 FT /note="LEPRPT, copy 5, 605 bp identical to 3' part of FT LEPRPT. Last 50 bp only present in this copy and in one FT other at 1539935..1539886" FT repeat_region 205567..205616 FT /note="50 bp repeat, associated with only 2 copies of FT LEPRPT" FT CDS complement(205776..206129) FT /transl_table=11 FT /gene="ML1821" FT /product="very hypothetical protein" FT /note="questionable CDS." FT /db_xref="UniProtKB/TrEMBL:Q9CBL0" FT /protein_id="CAC30774.1" FT /translation="MVVSYRLSNRLSHQTRFALVLAGDTRCLPRNGGVWAGHNDGYVGV FT YGCGELSAKLAVLWFPNQGSEDVHRPIDAGVDGQSRSVRLTKYPLSTASDPHGLTTTWF FT DDRCKAKSSGSLP" FT CDS 206631..207278 FT /pseudo FT /transl_table=11 FT /gene="ML1822" FT /product="probable cutinase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv2301 (Best blastx score 415)" FT CDS complement(208154..209676) FT /pseudo FT /transl_table=11 FT /gene="ML1823" FT /product="putative transposase (pseudogene)" FT repeat_region complement(208495..209755) FT /note="1261 bp repeat, 100% identical to region FT 2113323..2114583" FT repeat_region complement(209758..211863) FT /note="Dispersed repeat, LEPREP, copy 5. Truncated at FT 3'-end " FT CDS complement(210031..211174) FT /pseudo FT /transl_table=11 FT /gene="ML1824" FT /product="putative group II intron maturase-related FT protein" FT /note="Similar to many e.g. Cryphonectria parasitica FT (Chesnut blight fungus) putative maturase TR:AAF27656 FT (EMBL:AF218567) (778 aa) fasta scores: E(): 7.8e-11, 29.2% FT id in 216 aa" FT stem_loop complement(210494..210547) FT CDS complement(211379..211518) FT /pseudo FT /transl_table=11 FT /gene="ML1825" FT /note="Similar to Pseudomonas putida transposase tnpa1 FT TR:Q9R9U9 (EMBL:AJ245436) (355 aa) fasta scores: E(): FT 3.4e-05, 47.8% id in 46 aa, and to Agrobacterium FT tumefaciens transposase TR:Q44454 (EMBL:Z18270) (366 aa) FT fasta scores: E(): 0.00026, 41.3% id in 46 aa" FT CDS complement(212611..212812) FT /pseudo FT /transl_table=11 FT /gene="cobU" FT /gene_synonym="ML1826" FT /product="cobinamide kinase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT cobU (Best blastx score 185)" FT CDS complement(212887..213523) FT /pseudo FT /transl_table=11 FT /gene="cobQ" FT /gene_synonym="ML1827" FT /product="cobyric acid synthase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT cobQ (Best blastx score 336)" FT CDS complement(213498..215216) FT /transl_table=11 FT /gene="PPE" FT /gene_synonym="ML1828" FT /product="PPE-family protein" FT /note="Similar to Mycobacterium tuberculosis PPE-family FT proteins e.g. Rv0256c or MTV034.22C TR:O53678 FT (EMBL:AL021929) (556 aa) fasta scores: E(): 0, 63.5% id in FT 564 aa. Previously sequenced as TR:O33009 (EMBL:Z98756). FT Contains Pfam match to entry PF00823 PPE, PPE family." FT /db_xref="InterPro:IPR000030" FT /db_xref="UniProtKB/TrEMBL:O33009" FT /protein_id="CAC30781.1" FT /translation="MSAPIWMASPPEVHSALLSRGPGSGPLLVAAEAWRSLSSVYAEMA FT DELVALLVVVPVSSWDGSAAEAYVIAYLPYLGWLRQASVDSAVMAAHYETMATAYITTL FT AMMPTLAELAANRTAHTVLVTTNFFGINTIPIARNEIDYVRMWVEAAIAMGTYQEVSTV FT VVDSAPEAIAAPQIMASDALEASSDQPSPTAPSQSPQVQNWLQWLQKIGYTDFYNTLVQ FT PLITSLTNHPFFQGMFSGFDPWLPSLGNPLSFLSPFNIAFALGTPMDIGSYVGYLSQTF FT AFIGADLAAAFASGNPVTIGFTLLFTTIEAIGTIITDTIALVKTMIEQSFVLLPMILPL FT LTAPLAVATAGAAGSFAGLSELAGLVGVAPPGLPSAPPVAAVAPVVPPSMPTLASIPTP FT TPMPAPAASTAPVVTPPGPPPVTAPPSVTGAGVESFGYLVGRLPSTARGVVGTSVRQQS FT SAPDRIEAPDAAATPQEQARSRWRRRAKVTPFDSSGSPNPKAAPTASDQGAGTLGLAGT FT ARQASSGPATGLVTLSNGTFSDSPRAPMLPRTWGADPTFCYNAADIGPAGGWDDE" FT misc_feature complement(214719..215195) FT /note="Pfam match to entry PF00823 PPE, PPE family, score FT 303.90, E-value 1.9e-87" FT CDS 215347..215550 FT /pseudo FT /transl_table=11 FT /gene="ML1828A" FT /product="conserved hypothetical protein (pseudogene)" FT /note="ML1828A. Unknown but orthologous to M. tuberculosis FT Rv0257 (124 aa). BLASTP score: 1e-15 Identities = 38/46 FT (82%). Probably pseudogene as Rv0257 is longer" FT /db_xref="PSEUDO:CAC30782.1" FT CDS 215863..216240 FT /transl_table=11 FT /gene="ML1829" FT /product="hypothetical protein" FT /note="Unknown function." FT /db_xref="UniProtKB/TrEMBL:Q9CBK9" FT /protein_id="CAC30783.1" FT /translation="MRCSASAPGLTGDLAHGQQITVPVTRPYSASTTHLGMITTLKQTA FT GVADTGDTVTPRIRQRVTVGKITEYTPGQQVNVAAVITDHPDMMVTTAPTICIMPFGVD FT NHVDAEWLKLTSLGLRPRAIR" FT CDS complement(217101..217918) FT /pseudo FT /transl_table=11 FT /gene="ML1830" FT /product="putative aminotransferase (pseudogene)" FT CDS complement(220452..221252) FT /transl_table=11 FT /gene="mapA" FT /gene_synonym="ML1831" FT /product="probable methionine aminopeptidase" FT /note="Similar to M. tuberculosis methionine aminopeptidase FT map' Rv0734 TR:O53797 (EMBL:AL021958) (266 aa); Fasta score FT E(): 0, 84.0% identity in 262 aa overlap, and to many FT others e.g. Bacillus subtilis methionine aminopeptidase FT SW:AMPM_BACSU (P19994) (248 aa); Fasta score E(): 0, 43.3% FT identity in 245 aa overlap. Contains Pfam match to entry FT PF00557 Peptidase_M24, metallopeptidase family M24." FT /note="Similar to ML1576 and ML0521" FT /db_xref="GOA:O33008" FT /db_xref="HSSP:1O0X" FT /db_xref="InterPro:IPR002467" FT /db_xref="UniProtKB/TrEMBL:O33008" FT /protein_id="CAC30785.1" FT /translation="MGALTRLRSRRVVPQRSVGELDAMAAAGAVVAAALHAVRDAAGPG FT VSSLSLDEIAESVIREAGATPSFLRYHGYPATICTSVNDRVIHGIPSAVEILAPGDLVS FT IDCGAVLDGWHGDAAITFGVGTLTSVDEALSQATRESLEAGIAAMIVNNRLTDVAHAIE FT VSTRTSEIRYRLTFGIVQGYGGHGIGRHMHMDPFLPNEGAPGRGPLLVPGSVLAIEPML FT TLGTGKTIVLDDEWTVTTADGSRAAHWEHTVAVTEDGPRVLTLA" FT misc_feature complement(220470..221213) FT /note="Pfam match to entry PF00557 Peptidase_M24, FT metallopeptidase family M24, score 153.70, E-value 3.2e-42" FT CDS complement(221264..221809) FT /transl_table=11 FT /gene="adk" FT /gene_synonym="ML1832" FT /product="probable adenylate kinase" FT /note="Similar to M. tuberculosis adenylate kinase adk FT Rv0733 SW:KAD_MYCTU (O53796) (181 aa); Fasta score E(): 0, FT 83.4% identity in 181 aa overlap, and to many thers e.g. FT Bacillus subtilis adenylate kinase SW:KAD_BACSU (P16304) FT (217 aa); Fasta score E(): 2.9e-20, 39.3% identity in 211 FT aa overlap. Contains Pfam match to entry PF00406 FT adenylatekinase, Adenylate kinase. Contains PS00113 FT Adenylate kinase signature." FT /db_xref="GOA:O33007" FT /db_xref="HSSP:1ZIN" FT /db_xref="InterPro:IPR000850" FT /db_xref="UniProtKB/Swiss-Prot:O33007" FT /protein_id="CAC30786.1" FT /translation="MRVVLLGPPGAGKGTQAQRLAEKLGIPQISTGELFRRNIEKDTKL FT GHEAKKYLDAGDLVPADLTNQLVDDRLNKSDTVDGFILDGYPRSLEQAKALHEMLERRG FT TDIDAVLEFRVSQAVVLERLKGRGRADDTDDVVINRMNIYRDETASLLEYYSSELKTID FT AIGTMDEVFARALHALGK" FT misc_feature complement(221330..221797) FT /note="Pfam match to entry PF00406 adenylatekinase, FT Adenylate kinase, score 238.10, E-value 1.2e-67" FT misc_feature complement(221534..221569) FT /note="PS00113 Adenylate kinase signature" FT CDS complement(221806..223122) FT /transl_table=11 FT /gene="secY" FT /gene_synonym="ML1833" FT /product="SecY subunit of preprotein translocase" FT /note="Similar to M. tuberculosis preprotein translocase FT secy subunit RV0732 SW:SECY_MYCTU (P94926) (441 aa); Fasta FT score E(): 0, 91.6% identity in 441 aa overlap, and to many FT others e.g. Bacillus subtilis SW:SECY_BACSU (P16336) (431 FT aa); Fasta score E(): 0, 42.7% identity in 445 aa overlap. FT Contains Pfam match to entry PF00344 secY, eubacterial secY FT protein. Contains PS00017 ATP/GTP-binding site motif A FT (P-loop). Contains PS00756 Protein secY signature 2." FT /db_xref="GOA:O33006" FT /db_xref="InterPro:IPR002208" FT /db_xref="UniProtKB/Swiss-Prot:O33006" FT /protein_id="CAC30787.1" FT /translation="MLSAFISSLRTVDLRRKILFTLGILVLYRVSAALPSPGVNYRHVQ FT QCIQEATAGEAGEIYSLINLFSGGALLKLTVGVMPYITASIIVQLLTVVIPRFEELRKE FT GQAGQAKMTQYTRYLAIALAVLQATSIVALAANGGLLQGCQEDIISDQSIFSLVVIVLV FT MTGGAALVMWMGELITERGIGNGMSLLIFVGIAARIPAEGKQILDSRGGVIFAAVCLAA FT LVIIVGVVFVEQGQRRIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYI FT PHLITQLVRSGSGGVGKSWWDKFVGTYLSDPADPVYINIYFGLIIFFTYFYVSVTFNPD FT ERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGSIYLGAIAVLPNLFLQIGNGGE FT VQNLPFGGTAVLIMIGVGLDTVKQIESQLMQRNYEGFLK" FT misc_feature complement(221854..222903) FT /note="Pfam match to entry PF00344 secY, eubacterial secY FT protein, score 591.10, E-value 7e-174" FT misc_feature complement(222226..222249) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(222550..222606) FT /note="PS00756 Protein secY signature 2" FT CDS 223503..224170 FT /pseudo FT /transl_table=11 FT /gene="ML1834" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0731c (Best blastx score 125)" FT CDS complement(224266..224949) FT /transl_table=11 FT /gene="ML1835" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis hypothetical protein FT Rv0730 TR:O53794 (EMBL:AL021958) (242 aa); Fasta score E(): FT 0, 83.5% identity in 218 aa overlap." FT /db_xref="UniProtKB/TrEMBL:O33005" FT /protein_id="CAC30789.1" FT /translation="MTDHDQTAARRETADALLKALERRHEIADAVVEAENKPAAVEAIV FT KLLDTSRLAAEAVMSMSFDRLTKDSRKKILAELEDLNKQLSFTLQERPASLGESLELRP FT FSGEDDRDIFAARTAEINSAGDGSGGPAGSIDDEIRAALVRVADEEAAWFVAVDSGAKV FT GMVFGELVHGEVDVRVWICPDHRKKGYGTAALRKSRSEMAYCFPAVPMVARAPAADLHS FT RITAD" FT CDS complement(225043..226043) FT /pseudo FT /transl_table=11 FT /gene="xylB" FT /gene_synonym="ML1836" FT /product="xylulose kinase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT xylB (Best blastx score 417)" FT CDS 226078..227059 FT /pseudo FT /transl_table=11 FT /gene="ML1837" FT /product="similar to D-3-phosphoglycerate dehydrogenases FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0728c (Best blastx score 581)" FT CDS 227139..227496 FT /pseudo FT /transl_table=11 FT /gene="fucA" FT /gene_synonym="ML1838" FT /product="L-fuculose phosphate aldolase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT fucA (Best blastx score 229)" FT CDS complement(227986..229794) FT /transl_table=11 FT /gene="sppA" FT /gene_synonym="ML1839" FT /product="protease IV, signal peptide peptidase" FT /note="Similar to M. tuberculosis protease IV, signal FT peptide peptidase Rv0724, TR:P95072 (EMBL:Z84395) (623 aa); FT Fasta score E(): 0, 80.2% identity in 602 aa overlap, and FT to many others e.g. Escherichia coli protease IV FT SW:SPPA_ECOLI (P08395) (618 aa); Fasta score E(): 2.3e-24, FT 33.1% identity in 531 aa overlap. Contains 2 Pfam matches FT to entry PF01343 Peptidase_U7, Peptidase family U7." FT /db_xref="GOA:O33003" FT /db_xref="InterPro:IPR005479" FT /db_xref="UniProtKB/TrEMBL:O33003" FT /protein_id="CAC30793.1" FT /translation="MSAFLPPFPGIDDVRALANRVNTARHHGIPNGCVLEVNLRSLPPE FT TTSFDPFTIITRGGRPMALREAVAAIHRAAADPRVAGMIARVQLGASPPAAVQELREAV FT ATFSAVKPSLAWAETYPGTLSYYLASAFGEVWMQPSGSVGLVGFASNATFLRDVLAKVG FT IEAQFVARGEYKSAANLFTEGGFTDAHREAVSRMLESLQGQVWQGIAESRRIDPAALNP FT LADRAPLLRDDAVASGLVDRIGFRDEAYARIAELVGAESITPNSSEPQARTEANDGLPR FT LYLSRYASAGRSRLMPPMPLIPGRRSKPTVVVVTLEGPIVNGRGGPQFLPFGISTGGGD FT TIAAALREVAADDSVSAIVLRVNSPGGSVTASETIWREVKRARDRGKPVVVSMGAVAAS FT GGYYVSVGADEIVANPGTITGSIGVITGKLVIRDLKGRLGVGSDTVRTNANADAWSANV FT PFTPEQHTHREAEADLCYADFLERVAEGRGMTTDAVDDVARGRIWTGADALERGLVDEL FT GGLVTAVRRAKVLAGLDADVDVRIVSYPGSSLLDMVRPRASSQPGAASLPDAVATLLGR FT SVAGILEQVEQALSGVRVLWLGEYRF" FT misc_feature complement(228193..228654) FT /note="Pfam match to entry PF01343 Peptidase_U7, Peptidase FT family U7, score 234.70, E-value 1.3e-66" FT misc_feature complement(229015..229482) FT /note="Pfam match to entry PF01343 Peptidase_U7, Peptidase FT family U7, score 188.70, E-value 9e-53" FT CDS complement(230030..230470) FT /transl_table=11 FT /gene="rplO" FT /gene_synonym="ML1840" FT /product="50S ribosomal protein L15" FT /note="Similar to M. tuberculosis 50S ribosomal protein L15 FT Rv0723 SW:RL15_MYCTU (P95071) (146 aa); Fasta score E(): 0, FT 81.5% identity in 146 aa overlap. Contains Pfam match to FT entry PF00256 L15, Ribosomal protein L15. Contains Pfam FT match to entry PF01305 Ribosomal_L15, Ribosomal protein L15 FT amino terminal region. Contains PS00017 ATP/GTP-binding FT site motif A (P-loop). Contains PS00475 Ribosomal protein FT L15 signature." FT /db_xref="GOA:O33002" FT /db_xref="InterPro:IPR005749" FT /db_xref="UniProtKB/Swiss-Prot:O33002" FT /protein_id="CAC30794.1" FT /translation="MTIKLHDLQPARGSKTTRTRVGRGEASKGKTAGRGTKGTKARKQV FT PVTFEGGQMPIHMRLPKLKGFRNRLRTEYAVVNVGDISRLFPEGGTISVNDLVAKKAIR FT KNSLVKILGDGKLTVKVTLSAHKFSGSARHKITVAGGSVTEL" FT misc_feature complement(230048..230143) FT /note="Pfam match to entry PF00256 L15, Ribosomal protein FT L15, score 43.00, E-value 2.9e-14" FT misc_feature complement(230051..230143) FT /note="PS00475 Ribosomal protein L15 signature" FT misc_feature complement(230162..230464) FT /note="Pfam match to entry PF01305 Ribosomal_L15, Ribosomal FT protein L15 amino terminal region, score 209.60, E-value FT 4.8e-59" FT misc_feature complement(230378..230401) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(230471..230686) FT /transl_table=11 FT /gene="rpmD" FT /gene_synonym="ML1841" FT /product="50S ribosomal protein L30" FT /note="Similar to M. tuberculosis 50S ribosomal protein L30 FT Rv0722 SW:RL30_MYCTU (Z84395) (65 aa); Fasta score E(): FT 1.1e-21, 89.2% identity in 65 aa overlap. Contains Pfam FT match to entry PF00327 Ribosomal_L30, Ribosomal protein FT L30p/L7e." FT /db_xref="GOA:O33001" FT /db_xref="InterPro:IPR000517" FT /db_xref="UniProtKB/Swiss-Prot:O33001" FT /protein_id="CAC30795.1" FT /translation="MASLKITQVRSTIGVRWKQRESLRTLGLRRIRHSVIREDNLQTRG FT LIAVVRHLVEVEPATGGSTPVGGGRD" FT misc_feature complement(230525..230683) FT /note="Pfam match to entry PF00327 Ribosomal_L30, Ribosomal FT protein L30p/L7e, score 59.00, E-value 2e-16" FT CDS complement(230689..231342) FT /transl_table=11 FT /gene="rpsE" FT /gene_synonym="ML1842" FT /product="30S ribosomal protein S5" FT /note="Similar to M. tuberculosis 30S ribosomal protein S5 FT Rv0721 SW:RS5_MYCTU (P95069) (220 aa); Fasta score E(): 0, FT 87.9% identity in 190 aa overlap. Contains Pfam match to FT entry PF00333 Ribosomal_S5, Ribosomal protein S5. Contains FT PS00585 Ribosomal protein S5 signature." FT /db_xref="GOA:O33000" FT /db_xref="HSSP:1PKP" FT /db_xref="InterPro:IPR018192" FT /db_xref="UniProtKB/Swiss-Prot:O33000" FT /protein_id="CAC30796.1" FT /translation="MAAQSAGLLGDSREGRSRREGGSRGGRDRDRDGEKGNYLERVVAI FT NRVSKVVKGGRRFSFTALVIVGDGHGMVGVGYGKAKEVPAAIAKGVEEARKSFFRVPLI FT DGTITHPVQGEAAAGVVLLRPASPGTGVIAGGAVRAVLECAGVHDILAKSLGSDNAINV FT VHATVAALKLLQRPDEVAARRGLRSGMLPRSWDPAGVAGERSVDRPVGRVREQA" FT misc_feature complement(230833..231219) FT /note="Pfam match to entry PF00333 Ribosomal_S5, Ribosomal FT protein S5, score 248.40, E-value 1e-70" FT misc_feature complement(231082..231180) FT /note="PS00585 Ribosomal protein S5 signature" FT CDS complement(231371..231736) FT /transl_table=11 FT /gene="rplR" FT /gene_synonym="ML1843" FT /product="50S ribosomal protein L18" FT /note="Similar to M. tuberculosis 50S ribosomal protein L18 FT Rv0720 SW:RL18_MYCTU (P95068) (122 aa); Fasta score E(): 0, FT 87.5% identity in 120 aa overlap. Contains Pfam match to FT entry PF00861 Ribosomal_L18p, Ribosomal L18p/L5e family." FT /db_xref="GOA:O32999" FT /db_xref="HSSP:1ILY" FT /db_xref="InterPro:IPR004389" FT /db_xref="UniProtKB/Swiss-Prot:O32999" FT /protein_id="CAC30797.1" FT /translation="MQSVSAIRRVSRLRRHARLRKKVSGTSERPRLVVNRSARHIHVQL FT VNDVTGTTVAAASSIEADVRGLQGDKKVRSVRVGQLIAERAKAAGINTVVFDRGGYTYG FT GRIAALADSVRENGLNF" FT misc_feature complement(231374..231718) FT /note="Pfam match to entry PF00861 Ribosomal_L18p, FT Ribosomal L18p/L5e family, score 178.40, E-value 1.2e-49" FT CDS complement(231742..232281) FT /transl_table=11 FT /gene="rplF" FT /gene_synonym="ML1844" FT /product="50S ribosomal protein L6" FT /note="Similar to M. tuberculosis 50S ribosomal protein L6 FT Rv0719 SW:RL6_MYCTU (P95067) (179 aa); Fasta score E(): 0, FT 90.5% identity in 179 aa overlap. Contains Pfam match to FT entry PF00347 Ribosomal_L6, Ribosomal protein L6. Contains FT PS00525 Ribosomal protein L6 signature 1." FT /db_xref="GOA:O32998" FT /db_xref="HSSP:1C04" FT /db_xref="InterPro:IPR019906" FT /db_xref="UniProtKB/Swiss-Prot:O32998" FT /protein_id="CAC30798.1" FT /translation="MSRIGKQPIPVPAGVDITIDGQNVLVKGPKGTLDLTVAEPIMLAR FT NDEGAIVVTRPDNERRNRSLHGLSRTLVSNLVTGVTQGYTVSMEIFGVGYRAQLKGSNL FT EFALGYSHPVVIEAPEGITFAVQSPTKFTITGIDKQKVGQISANIRRLRRPDPYKGKGV FT RYEGEQIRRKVGKTGK" FT misc_feature complement(231745..232251) FT /note="Pfam match to entry PF00347 Ribosomal_L6, Ribosomal FT protein L6, score 284.80, E-value 8.8e-82" FT misc_feature complement(231793..231819) FT /note="PS00525 Ribosomal protein L6 signature 1" FT CDS complement(232307..232705) FT /transl_table=11 FT /gene="rpsH" FT /gene_synonym="ML1845" FT /product="30S ribosomal protein S8" FT /note="Similar to M. tuberculosis 30S ribosomal protein S8 FT RV0718 SW:RS8_MYCTU (P95066) (132 aa); Fasta score E(): 0, FT 93.9% identity in 132 aa overlap. Contains Pfam match to FT entry PF00410 Ribosomal_S8, Ribosomal protein S8. Contains FT PS00053 Ribosomal protein S8 signature." FT /db_xref="GOA:O32997" FT /db_xref="HSSP:1SEI" FT /db_xref="InterPro:IPR000630" FT /db_xref="UniProtKB/Swiss-Prot:O32997" FT /protein_id="CAC30799.1" FT /translation="MTMTDPIADFLTRLRNANSAYHDEVTVPHSNIKANIAQILKNEGY FT IRDFRTEDARVGKSLIIQLKYGPSRERSIAGLRRVSKPGLRVYAKSINLPRVLGGLGVV FT IISTSSGLLTDRQAARQGVGGEVLAYVW" FT misc_feature complement(232310..232693) FT /note="Pfam match to entry PF00410 Ribosomal_S8, Ribosomal FT protein S8, score 233.40, E-value 1.3e-70" FT misc_feature complement(232349..232402) FT /note="PS00053 Ribosomal protein S8 signature" FT CDS complement(232788..232973) FT /transl_table=11 FT /gene="rpsN" FT /gene_synonym="ML1846" FT /product="30S ribosomal protein S14" FT /note="Similar to M. tuberculosis 30S ribosomal protein FT S14-1 Rv0717 SW:R14A_MYCTU (P95065) (61 aa); Fasta score FT E(): 1.8e-25, 91.8% identity in 61 aa overlap. Contains FT Pfam match to entry PF00253 Ribosomal_S14, Ribosomal FT protein S14p/S29e. Contains PS00527 Ribosomal protein S14 FT signature." FT /db_xref="GOA:O32996" FT /db_xref="InterPro:IPR018271" FT /db_xref="UniProtKB/Swiss-Prot:O32996" FT /protein_id="CAC30800.1" FT /translation="MAKKALVNKAARKPKFTVRGYTRCSKCGRPRAVFRKFGLCRICLR FT EMAHAGELPGVQKSSW" FT misc_feature complement(232791..232973) FT /note="Pfam match to entry PF00253 Ribosomal_S14, Ribosomal FT protein S14p/S29e, score 98.60, E-value 3.3e-29" FT misc_feature complement(232839..232907) FT /note="PS00527 Ribosomal protein S14 signature" FT CDS complement(232979..233542) FT /transl_table=11 FT /gene="rplE" FT /gene_synonym="ML1847" FT /product="50S ribosomal protein L5" FT /note="Similar to M. tuberculosis 50S ribosomal protein L5 FT Rv0716 SW:RL5_MYCTU (P95064) (187 aa); Fasta score E(): 0, FT 91.4% identity in 187 aa overlap. Contains Pfam match to FT entry PF00281 Ribosomal_L5, Ribosomal protein L5. Contains FT Pfam match to entry PF00673 Ribosomal_L5_C, ribosomal L5P FT family C-terminus." FT /db_xref="GOA:O32995" FT /db_xref="HSSP:1MJI" FT /db_xref="InterPro:IPR002132" FT /db_xref="UniProtKB/Swiss-Prot:O32995" FT /protein_id="CAC30801.1" FT /translation="MSTAEKVQPRLKQRYRSEIREALNKQFSYGNVMQIPTVVKVVVNM FT GVGDAARDAKLINGAVSDLALITGQKPEVRKARKSIAQFKLREGMPIGVRVTLRDDRMW FT EFLDRLTSIALPRIRDFRGLSPKQFDGVGNYTFGLAEQSVFHEIDVDKIDRVRGMDINV FT VTSATTDDEGRALLRALGFPFKEN" FT misc_feature complement(232988..233272) FT /note="Pfam match to entry PF00673 Ribosomal_L5_C, FT ribosomal L5P family C-terminus, score 182.90, E-value FT 5e-51" FT misc_feature complement(233282..233452) FT /note="Pfam match to entry PF00281 Ribosomal_L5, Ribosomal FT protein L5, score 98.60, E-value 1.3e-25" FT CDS complement(233543..233860) FT /transl_table=11 FT /gene="rplX" FT /gene_synonym="ML1848" FT /product="50S ribosomal protein L24" FT /note="Similar to M. tuberculosis 50S ribosomal protein L24 FT Rv0715 SW:RL24_MYCTU (P95063) (105 aa); Fasta score E(): 0, FT 93.3% identity in 105 aa overlap. Contains Pfam match to FT entry PF00467 Ribosomal_L24, KOW motif. Contains PS01108 FT Ribosomal protein L24 signature." FT /db_xref="GOA:O32994" FT /db_xref="InterPro:IPR014723" FT /db_xref="UniProtKB/Swiss-Prot:O32994" FT /protein_id="CAC30802.1" FT /translation="MKVHKGDTVLVIAGKDKGAKGKVLQAYPARNRVLVEGVNRIKKHT FT AISANQRGAQAGGIVTQEAPIHVSNVMVVDSDGKPTRIGYRVDEETDKRVRISKRNGKD FT I" FT misc_feature complement(233675..233854) FT /note="Pfam match to entry PF00467 Ribosomal_L24, KOW FT motif, score 94.60, E-value 2e-24" FT misc_feature complement(233792..233845) FT /note="PS01108 Ribosomal protein L24 signature" FT CDS complement(233861..234202) FT /transl_table=11 FT /gene="rplN" FT /gene_synonym="ML1849" FT /product="50S ribosomal protein L14" FT /note="Similar to M. tuberculosis 50S ribosomal protein L14 FT Rv0714 SW:RL14_MYCTU (P95062) (122 aa); Fasta score E(): 0, FT 96.5% identity in 113 aa overlap. Contains Pfam match to FT entry PF00238 Ribosomal_L14, Ribosomal protein L14p/L23e. FT Contains PS00049 Ribosomal protein L14 signature." FT /db_xref="GOA:O32993" FT /db_xref="HSSP:1WHI" FT /db_xref="InterPro:IPR019972" FT /db_xref="UniProtKB/Swiss-Prot:O32993" FT /protein_id="CAC30803.1" FT /translation="MADNTGAKEILCIRVLGGSSRRYASIGDVIVGTVKDAIPGGNVKR FT GDVVKAVVVRTAKECRRPDGSYIKFDENAAVIIKPDNDPRGTRIFGPVGRELREKRFMK FT IISLAPEVL" FT misc_feature complement(233864..234202) FT /note="Pfam match to entry PF00238 Ribosomal_L14, Ribosomal FT protein L14p/L23e, score 238.10, E-value 1.2e-67" FT misc_feature complement(233972..234052) FT /note="PS00049 Ribosomal protein L14 signature" FT repeat_region complement(234447..235500) FT /note="1054 bp repeat, 100% identical to bases FT 1538642..1539695" FT CDS complement(234502..235498) FT /pseudo FT /transl_table=11 FT /gene="ML1850" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv0336" FT CDS complement(235794..236660) FT /pseudo FT /transl_table=11 FT /gene="ML1851" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0712 (Best blastx score 304)" FT CDS complement(236798..237079) FT /pseudo FT /transl_table=11 FT /gene="ML1852" FT /product="integral membrane protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0713" FT CDS complement(237270..238513) FT /pseudo FT /transl_table=11 FT /gene="atsA" FT /gene_synonym="ML1853" FT /product="arylsulfatase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT atsA (Best blastx score 344)" FT CDS complement(239399..239782) FT /transl_table=11 FT /gene="rpsQ" FT /gene_synonym="ML1854" FT /product="30S ribosomal protein S17" FT /note="Similar to M. tuberculosis 30S ribosomal protein S17 FT Rv0710 SW:RS17_MYCTU (P95058) (136 aa); Fasta score E(): FT 1.5e-29, 77.2% identity in 136 aa overlap. Contains Pfam FT match to entry PF00366 Ribosomal_S17, Ribosomal protein FT S17. Contains PS00056 Ribosomal protein S17 signature." FT /db_xref="GOA:O32990" FT /db_xref="HSSP:1RIP" FT /db_xref="InterPro:IPR019979" FT /db_xref="UniProtKB/Swiss-Prot:O32990" FT /protein_id="CAC30808.1" FT /translation="MMAAEAKTSAKAAPSATTAAPKGGAVKGGVSKDKGPKHTPSIPKV FT RGGRKMRIGYVVSDKMQKTIVVELEDRMRHPLYGKIIRTTKKVKAHDENSVAGIGDRVS FT LMETRPLSATKRWRLVEILEKAK" FT misc_feature complement(239417..239623) FT /note="Pfam match to entry PF00366 Ribosomal_S17, Ribosomal FT protein S17, score 124.50, E-value 9.3e-36" FT misc_feature complement(239447..239485) FT /note="PS00056 Ribosomal protein S17 signature" FT CDS complement(239779..240024) FT /transl_table=11 FT /gene="rpmC" FT /gene_synonym="ML1855" FT /product="50S ribosomal protein L29" FT /note="Similar to M. tuberculosis 50S ribosomal protein L29 FT Rv0709 SW:RL29_MYCTU (P95057) (77 aa); Fasta score E(): FT 2.5e-25, 91.9% identity in 74 aa overlap. Contains Pfam FT match to entry PF00831 Ribosomal_L29, Ribosomal L29 FT protein." FT /db_xref="GOA:O32989" FT /db_xref="InterPro:IPR018254" FT /db_xref="UniProtKB/Swiss-Prot:O32989" FT /protein_id="CAC30809.1" FT /translation="MMAVGISPGELRELTDEELIERLRESKEELFNLRFQMATGQLNNN FT RRLRTVRHEIARVYTVLRERELGLASGPGGANGEES" FT misc_feature complement(239815..240003) FT /note="Pfam match to entry PF00831 Ribosomal_L29, Ribosomal FT L29 protein, score 106.30, E-value 5.7e-28" FT CDS complement(240021..240437) FT /transl_table=11 FT /gene="rplP" FT /gene_synonym="ML1856" FT /product="50S ribosomal protein L16" FT /note="Similar to M. tuberculosis 50S ribosomal protein L16 FT RV0708 SW:RL16_MYCTU (P95056) (138 aa); Fasta score E(): 0, FT 96.4% identity in 138 aa overlap. Contains Pfam match to FT entry PF00252 Ribosomal_L16, Ribosomal protein L16. FT Contains PS00701 Ribosomal protein L16 signature 2." FT /db_xref="GOA:O32988" FT /db_xref="InterPro:IPR000114" FT /db_xref="UniProtKB/Swiss-Prot:O32988" FT /protein_id="CAC30810.1" FT /translation="MLIPRKVKHRKQHHPRQRGIASGGTKVNFGDYGIQALEHAYVTNR FT QIESARIAINRHIKRGGKVWINIFPDRPLTKKPAETRMGSGKGSPEWWVVNVKPGRVLF FT ELSYPNEQTARAALTRAIHKLPIKARIVTREEQF" FT misc_feature complement(240042..240437) FT /note="Pfam match to entry PF00252 Ribosomal_L16, Ribosomal FT protein L16, score 242.20, E-value 7e-70" FT misc_feature complement(240159..240194) FT /note="PS00701 Ribosomal protein L16 signature 2" FT CDS complement(240441..241286) FT /transl_table=11 FT /gene="rpsC" FT /gene_synonym="ML1857" FT /product="30S ribosomal protein S3" FT /note="Similar to M. tuberculosis 30S ribosomal protein S3 FT RV0707 SW:RS3_MYCTU (P95055) (273 aa); Fasta score E(): 0, FT 95.0% identity in 259 aa overlap. Contains Pfam match to FT entry PF00417 Ribosomal_S3_N, Ribosomal protein S3, FT N-terminal domain.. Contains Pfam match to entry PF00013 FT KH-domain, KH domain. Contains Pfam match to entry PF00189 FT Ribosomal_S3_C, Ribosomal protein S3, C-terminal domain.. FT Contains PS00548 Ribosomal protein S3 signature." FT /db_xref="GOA:O32987" FT /db_xref="InterPro:IPR008282" FT /db_xref="UniProtKB/Swiss-Prot:O32987" FT /protein_id="CAC30811.1" FT /translation="MGQKINPHGFRLGITTGWKSRWYADKQYAEYVKEDVAIRRLLSTG FT LERAGIADVEIERTRDRVRVDIHTARPGIVIGRRGTEADRIRADLEKLTCKQVQLNILE FT VKNPESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMS FT RSEFYREGRVPLHTLRADIDYGLHEAKTTFGRIGVKVWIYKGDIVGGKREVTAVAPAGA FT ERARRERPSGTRPRRSGAAGTTVTGTDAGRAVGGEESAATNIGHSDDSVVTHEPQIAES FT " FT misc_feature complement(240681..240935) FT /note="Pfam match to entry PF00189 Ribosomal_S3_C, FT Ribosomal protein S3, C-terminal domain., score 161.40, FT E-value 1.3e-49" FT misc_feature complement(240696..240800) FT /note="PS00548 Ribosomal protein S3 signature" FT misc_feature complement(241011..241097) FT /note="Pfam match to entry PF00013 KH-domain, KH domain, FT score 19.30, E-value 0.00022" FT misc_feature complement(241104..241283) FT /note="Pfam match to entry PF00417 Ribosomal_S3_N, FT Ribosomal protein S3, N-terminal domain., score 87.60, FT E-value 4.7e-27" FT CDS complement(241286..241813) FT /transl_table=11 FT /gene="rplV" FT /gene_synonym="ML1858" FT /product="50S ribosomal protein L22" FT /note="Similar to M. tuberculosis 50S ribosomal protein L22 FT Rv0706 SW:RL22_MYCTU (P95054) (197 aa); Fasta score E(): 0, FT 76.3% identity in 190 aa overlap. Contains Pfam match to FT entry PF00237 Ribosomal_L22, Ribosomal protein L22p/L17e. FT Contains PS00464 Ribosomal protein L22 signature." FT /db_xref="GOA:O32986" FT /db_xref="HSSP:1BXE" FT /db_xref="InterPro:IPR005727" FT /db_xref="UniProtKB/Swiss-Prot:O32986" FT /protein_id="CAC30812.1" FT /translation="MTTTEFPSAIAKARFVRVSPRKARRVIDLVRGRSVADALDILRWA FT PQAASEPVARVIASAAANAQNNNGLDPETLVVATVYAGEGPTAKRIRPRAQGRAFRIRR FT RTSHITVVVESRPVKDQRSAASTKARRAEASKTAGRAPAKKAGASSGATKMPPKKASVK FT TSEASETKGGSD" FT misc_feature complement(241469..241783) FT /note="Pfam match to entry PF00237 Ribosomal_L22, Ribosomal FT protein L22p/L17e, score 165.10, E-value 1.2e-45" FT misc_feature complement(241475..241549) FT /note="PS00464 Ribosomal protein L22 signature" FT CDS complement(241810..242091) FT /transl_table=11 FT /gene="rpsS" FT /gene_synonym="ML1859" FT /product="30S ribosomal protein S19" FT /note="Similar to M. tuberculosis 30S ribosomal protein S19 FT Rv0705 SW:RS19_MYCTU (P48947) (93 aa); Fasta score E(): 0, FT 96.8% identity in 93 aa overlap. Contains Pfam match to FT entry PF00203 Ribosomal_S19, Ribosomal protein S19. FT Contains PS00323 Ribosomal protein S19 signature." FT /db_xref="GOA:O32985" FT /db_xref="HSSP:1FJG" FT /db_xref="InterPro:IPR005732" FT /db_xref="UniProtKB/Swiss-Prot:O32985" FT /protein_id="CAC30813.1" FT /translation="MPRSLKKGPFVDDHLLKKVDVQNEKNTKQVIKTWSRRSTIIPDFI FT GHTFAVHDGRKHVPVFVTEAMVGHKLGEFAPTRTFKGHIKDDRKAKRR" FT misc_feature complement(241843..242085) FT /note="Pfam match to entry PF00203 Ribosomal_S19, Ribosomal FT protein S19, score 179.40, E-value 2.1e-51" FT misc_feature complement(241861..241935) FT /note="PS00323 Ribosomal protein S19 signature" FT CDS complement(242115..242957) FT /transl_table=11 FT /gene="rplB" FT /gene_synonym="ML1860" FT /product="50S ribosomal protein L2" FT /note="Similar to M. tuberculosis 50S ribosomal protein L2 FT Rv0704 SW:RL2_MYCTU (P95052) (280 aa); Fasta score E(): 0, FT 92.1% identity in 280 aa overlap. Contains Pfam match to FT entry PF00181 Ribosomal_L2, Ribosomal Proteins L2. Contains FT PS00467 Ribosomal protein L2 signature." FT /db_xref="GOA:O32984" FT /db_xref="HSSP:1RL2" FT /db_xref="InterPro:IPR014722" FT /db_xref="UniProtKB/Swiss-Prot:O32984" FT /protein_id="CAC30814.1" FT /translation="MAIRKYKPTTSGRRGASVSDFTDITRTKPEKALMRSLHGHGGRNV FT HGRITTRHKGGGHKRAYRLIDFRRNDTDGVNAKVAHIEYDPNRTANIALLHFLDGKKRY FT ILAPQGLSQGDVVESGANADIKPGNNLPLRNIPAGTLIHAVELRPGGGAKLARSAGSSI FT QLLGKESSYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRMRWKGKRPSVR FT GVVMNPVDHPHGGGEGKTSGGRHPVSPWGKPEGRTRKPNKSSNKLIVRRRRTGKKHAR" FT misc_feature complement(242136..242834) FT /note="Pfam match to entry PF00181 Ribosomal_L2, Ribosomal FT Proteins L2, score 406.20, E-value 3.2e-118" FT misc_feature complement(242268..242303) FT /note="PS00467 Ribosomal protein L2 signature" FT CDS complement(242987..243289) FT /transl_table=11 FT /gene="rplW" FT /gene_synonym="ML1861" FT /product="50S ribosomal protein L23" FT /note="Similar to M. tuberculosis 50S ribosomal protein L23 FT Rv0703 SW:RL23_MYCTU (P95051) (100 aa); Fasta score E(): 0, FT 85.0% identity in 100 aa overlap. Contains Pfam match to FT entry PF00276 Ribosomal_L23, Ribosomal protein L23. FT Contains PS00050 Ribosomal protein L23 signature." FT /db_xref="GOA:O32983" FT /db_xref="InterPro:IPR013025" FT /db_xref="UniProtKB/Swiss-Prot:O32983" FT /protein_id="CAC30815.1" FT /translation="MATIADSRDIILAPVISEKSYGLLDDNVYTFVVHPDSNKTQIKIA FT IEKIFSVKVASVNTSNRKGKCKRTRTGFGRRKNTKRAIVTLAPGSKSIDLFGTPA" FT misc_feature complement(242993..243268) FT /note="Pfam match to entry PF00276 Ribosomal_L23, Ribosomal FT protein L23, score 117.30, E-value 1.2e-33" FT misc_feature complement(243005..243052) FT /note="PS00050 Ribosomal protein L23 signature" FT CDS complement(243289..243981) FT /transl_table=11 FT /gene="rplD" FT /gene_synonym="ML1862" FT /product="50S ribosomal protein L4" FT /note="Similar to M. tuberculosis 50S ribosomal protein L4 FT Rv0702 SW:RL4_MYCTU (P95050) (223 aa); Fasta score E(): 0, FT 86.7% identity in 218 aa overlap. Contains Pfam match to FT entry PF00573 Ribosomal_L4, Ribosomal protein L4/L1 FT family." FT /db_xref="GOA:O32982" FT /db_xref="InterPro:IPR002136" FT /db_xref="UniProtKB/Swiss-Prot:O32982" FT /protein_id="CAC30816.1" FT /translation="MAAKVENGSNIRKIDVKTPDGKVDGTIELPAELFDAPANIALMHQ FT VVTAQRAAARQGTHSTKTRGDVSGGGRKPYRQKGTGRARQGSMRAPQFTGGGIVHGPKL FT RDYSQRTPKKMIAAALRGALSDRARNGRIHAVTELVVGKTPSTKSAKEFLGTLTDRKQV FT LVVIGRSDETGAKSVRNLPGVHLLSPDQLNTYDVLRADDLVFSVEALNSYIAAQQAAGT FT STPEKVSA" FT misc_feature complement(243334..243906) FT /note="Pfam match to entry PF00573 Ribosomal_L4, Ribosomal FT protein L4/L1 family, score 271.30, E-value 1.3e-77" FT CDS complement(243981..244637) FT /transl_table=11 FT /gene="rplC" FT /gene_synonym="ML1863" FT /product="50S ribosomal protein L3" FT /note="Similar to M. tuberculosis 50S ribosomal protein L3 FT Rv0701 SW:RL3_MYCTU (P95049) (217 aa); Fasta score E(): 0, FT 93.5% identity in 217 aa overlap. Contains Pfam match to FT entry PF00297 Ribosomal_L3, Ribosomal protein L3. Contains FT PS00474 Ribosomal protein L3 signature." FT /db_xref="GOA:P30762" FT /db_xref="InterPro:IPR019926" FT /db_xref="UniProtKB/Swiss-Prot:P30762" FT /protein_id="CAC30817.1" FT /translation="MMARKGILGTKLGMTQVFDENNRVVPVTVVKAGPNVVTRIRTLER FT DGYSAVQLAYGEISPRKVNKPVTGQYNSAGVNPRRYLAELRLDHPDAAAEYEVGQELTA FT EIFADATYVDVTGTSKGKGFSGTMKRHGFRGQGASHGAQAVHRRPGSIGGCATPARVFK FT GTRMAGRMGNDRVTVQNLLVHKVDTENGVLLIKGAVPGRTGGLVMVRSAIKRGEK" FT misc_feature complement(244008..244607) FT /note="Pfam match to entry PF00297 Ribosomal_L3, Ribosomal FT protein L3, score 273.60, E-value 2.3e-78" FT misc_feature complement(244248..244319) FT /note="PS00474 Ribosomal protein L3 signature" FT CDS complement(244650..244955) FT /transl_table=11 FT /gene="rpsJ" FT /gene_synonym="ML1864" FT /product="30S ribosomal protein S10" FT /note="Similar to M. tuberculosis 30S ribosomal protein S10 FT RV0700 SW:RS10_MYCTU (P95048) (101 aa); Fasta score E(): 0, FT 97.0% identity in 101 aa overlap. Contains Pfam match to FT entry PF00338 Ribosomal_S10, Ribosomal protein S10p/S20e. FT Contains PS00361 Ribosomal protein S10 signature." FT /db_xref="GOA:P30765" FT /db_xref="HSSP:1J5E" FT /db_xref="InterPro:IPR018268" FT /db_xref="UniProtKB/Swiss-Prot:P30765" FT /protein_id="CAC30818.1" FT /translation="MAGQKIRIRLKAYDHEAIDASARKIVETVVRTGANVVGPVPLPTE FT KNVYCVIRSPHKYKDSREHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ" FT misc_feature complement(244656..244943) FT /note="Pfam match to entry PF00338 Ribosomal_S10, Ribosomal FT protein S10p/S20e, score 220.60, E-value 2.3e-62" FT misc_feature complement(244824..244871) FT /note="PS00361 Ribosomal protein S10 signature" FT CDS complement(245721..246199) FT /pseudo FT /transl_table=11 FT /gene="ML1865" FT /product="PE-family protein (pseudogene)" FT /note="Possible pseudogene similar to M. tuberculosis FT PE-family proteins (Best blastx score 125)" FT CDS complement(246559..247954) FT /pseudo FT /transl_table=11 FT /gene="ML1866" FT /product="gmc-type oxidoreductase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0697 (Best blastx score 550)" FT CDS complement(247961..249173) FT /pseudo FT /transl_table=11 FT /gene="ML1867" FT /product="glycosyltransferase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0696 (Best blastx score 202)" FT CDS complement(249244..249762) FT /pseudo FT /transl_table=11 FT /gene="ML1868" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0695 (Best blastx score 251)" FT CDS complement(249795..250926) FT /pseudo FT /transl_table=11 FT /gene="lldD1" FT /gene_synonym="ML1869" FT /product="L-lactate dehydrogenase (cytochrome) FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT lldD1 (Best blastx score 506)" FT CDS complement(251020..252099) FT /pseudo FT /transl_table=11 FT /gene="pqqE" FT /gene_synonym="ML1870" FT /product="coenzyme pqq synthesis protein E (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT pqqE (Best blastx score 555)" FT CDS complement(252179..252439) FT /pseudo FT /transl_table=11 FT /gene="ML1871" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0692 (Best blastx score 123)" FT CDS 252637..253126 FT /pseudo FT /transl_table=11 FT /gene="ML1872" FT /product="transcriptional regulator (TetR/AcrR family) FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0691c (Best blastx score 122)" FT CDS 253307..253787 FT /pseudo FT /transl_table=11 FT /gene="ML1873" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0690c (Best blastx score 169)" FT CDS complement(254053..254869) FT /pseudo FT /transl_table=11 FT /gene="ML1874" FT /product="putative oxidoreductase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0688 (Best blastx score 266)" FT CDS complement(254929..255619) FT /pseudo FT /transl_table=11 FT /gene="ML1875" FT /product="putative dehydrogenase, SDR family (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0687 (Best blastx score 122)" FT CDS complement(255893..256561) FT /pseudo FT /transl_table=11 FT /gene="ML1876" FT /product="potential membrane protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0686 (Best blastx score 157)" FT CDS complement(256840..258030) FT /transl_table=11 FT /gene="tuf" FT /gene_synonym="ML1877" FT /product="elongation factor EF-Tu" FT /note="Similar to M. tuberculosis elongation factor TU FT Rv0685 SW:EFTU_MYCTU (P31501) (396 aa); Fasta score E(): 0, FT 94.9% identity in 396 aa overlap, and to many others e.g. FT Escherichia coli SW:EFTU_ECOLI (P02990) (393 aa); Fasta FT score E(): 0, 74.9% identity in 395 aa overlap. Contains FT Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu FT family. Contains PS00301 GTP-binding elongation factors FT signature. Contains PS00017 ATP/GTP-binding site motif A FT (P-loop)." FT /note="Similar to ML1498, ML1556, ML0611 and ML1878" FT /db_xref="GOA:P30768" FT /db_xref="HSSP:1ETU" FT /db_xref="InterPro:IPR004160" FT /db_xref="UniProtKB/Swiss-Prot:P30768" FT /protein_id="CAC30831.1" FT /translation="MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKFPNLNE FT SRAFDQIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQMDGA FT ILVVAATDGPMPQTREHVLLARQVGVPYILVALNKSDAVDDEELLELVEMEVRELLAAQ FT EFDEDAPVVRVSALKALEGDAKWVESVTQLMDAVDESIPAPVRETDKPFLMPVEDVFTI FT TGRGTVVTGRVERGVVNVNEEVEIVGIRQTTTKTTVTGVEMFRKLLDQGQAGDNVGLLL FT RGIKREDVERGQVVIKPGTTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDV FT TGVVTLPEGTEMVMPGDNTNISVTLIQPVAMDEGLRFAIREGGRTVGAGRVVKIIK" FT misc_feature complement(256903..258003) FT /note="Pfam match to entry PF00009 GTP_EFTU, Elongation FT factor Tu family, score 537.80, E-value 7.3e-158" FT misc_feature complement(257827..257874) FT /note="PS00301 GTP-binding elongation factors signature" FT misc_feature complement(257953..257976) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(258139..260244) FT /transl_table=11 FT /gene="fusA" FT /gene_synonym="ML1878" FT /product="elongation factor G" FT /note="Similar to M. tuberculosis elongation factor G FT RV0684 SW:EFG_MYCTU (O53790) (701 aa); Fasta score E(): 0, FT 90.3% identity in 701 aa overlap, and to many others e.g. FT Escherichia coli SW:EFG_ECOLI (P02996) (703 aa); Fasta FT score E(): 0, 59.2% identity in 703 aa overlap. Contains FT Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu FT family. Contains Pfam match to entry PF00679 EFG_C, FT Elongation factor G C-terminus. Contains PS00301 FT GTP-binding elongation factors signature. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop)." FT /note="Similar to ML1498, ML0611, ML1877 and ML1556" FT /db_xref="GOA:P30767" FT /db_xref="HSSP:1FNM" FT /db_xref="InterPro:IPR004161" FT /db_xref="UniProtKB/Swiss-Prot:P30767" FT /protein_id="CAC30832.1" FT /translation="MAQKDVLTDLTKVRNIGIMAHIDAGKTTTTERILYYTGISYKIGE FT VHDGAATMDWMEQEQERGITITSAATTCFWNDNQINIIDTPGHVDFTVEVERSLRVLDG FT AVAVFDGKEGVEPQSEQVWRQADKYEVPRICFVNKMDKIGADFYFSVRTMQERLGANVI FT PIQLPVGSEGDFEGVVDLVEMKAKVWSTEAKLGEKYDVVGIPTDLQEKAEEYRTNLLET FT VAETDEALLEKYFSGEELTVAEIKGAIRKLTISSEAYPVLCGSAFKNKGVQPMLDAVID FT YLPSPLDVPAAIGHVPGKEDEEIVRKPSTDEPLSALAFKVATHPFFGKLTYVRVYSGKV FT DSGSQVINATKGKKERLGKLFQMHSNKENPVETASAGHIYAVIGLKDTTTGDTLADPNN FT QIVLESMTFPDPVIEVAIEPKTKSDQEKLSLSIQKLAEEDPTFKVHLDSETGQTVIGGM FT GELHLDILVDRMRREFKVEANVGKPQVAYKETIRRVVETVEYTHKKQTGGSGQFAKVII FT KLEPFSGENGATYEFENKVTGGRIPREYIPSVEAGARDAMQYGVLAGYPLVNLKVTLLD FT GAYHDVDSSEIAFKIAGSQVLKKAAAQAQPVILEPIMAVEVTTPEDYMGDVIGDLHSRR FT GQIQAMKERAGTRVVRAHVPLSEMFGYVGDLRSKTQGRANYSMVFNSYSEVPANVSKEI FT IAKATGE" FT misc_feature complement(258175..258690) FT /note="Pfam match to entry PF00679 EFG_C, Elongation factor FT G C-terminus, score 372.60, E-value 4e-108" FT misc_feature complement(258769..260214) FT /note="Pfam match to entry PF00009 GTP_EFTU, Elongation FT factor Tu family, score 664.00, E-value 7.5e-196" FT misc_feature complement(260038..260085) FT /note="PS00301 GTP-binding elongation factors signature" FT misc_feature complement(260164..260187) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(260338..260808) FT /transl_table=11 FT /gene="rpsG" FT /gene_synonym="ML1879" FT /product="30S ribosomal protein S7" FT /note="Similar to Mycobacterium tuberculosis 30s ribosomal FT protein S7 rpsG or rps7 or Rv0683 or MTV040.11 SW:RS7_MYCTU FT (P41194) (155 aa) fasta scores: E(): 0, 98.1% id in 155 aa FT and to Mycobacterium smegmatis 30s ribosomal protein S7 FT rpsG SW:RS7_MYCSM (P41193) (155 aa) fasta scores: E(): 0, FT 95.5% id in 155 aa. Previously sequenced as SW:RS7_MYCLE FT (P30764). Contains Pfam match to entry PF00177 FT Ribosomal_S7, Ribosomal protein S7p/S5e. Contains PS00052 FT Ribosomal protein S7 signature." FT /db_xref="GOA:P30764" FT /db_xref="HSSP:1HUS" FT /db_xref="InterPro:IPR005717" FT /db_xref="UniProtKB/Swiss-Prot:P30764" FT /protein_id="CAC30833.1" FT /translation="MPRKGPAPKRPLVNDPVYGSQLVTQLVNKILLKGKKSLAERIVYG FT ALEHARDKTGTDPVITLKRALDNVKPALEVRSRRVGGATYQVPVEVRPDRSTTLALRWL FT VGFSRQRREKTMIERLANEILDASNGLGASVKRREDTHKMAEANRAFAHYRW" FT misc_feature complement(260341..260808) FT /note="Pfam match to entry PF00177 Ribosomal_S7, Ribosomal FT protein S7p/S5e, score 329.10, E-value 4.9e-95" FT misc_feature complement(260671..260751) FT /note="PS00052 Ribosomal protein S7 signature" FT CDS complement(260808..261182) FT /transl_table=11 FT /gene="rpsL" FT /gene_synonym="ML1880" FT /product="30S ribosomal protein S12" FT /note="Similar to M. tuberculosis 30S ribosomal protein S12 FT RPS12 SW:RS12_MYCTU (P41196) (124 aa); Fasta score E(): 0, FT 97.6% identity in 123 aa overlap. Contains Pfam match to FT entry PF00164 Ribosomal_S12, Ribosomal protein S12. FT Contains PS00055 Ribosomal protein S12 signature." FT /db_xref="GOA:P30766" FT /db_xref="HSSP:1J5E" FT /db_xref="InterPro:IPR005679" FT /db_xref="UniProtKB/Swiss-Prot:P30766" FT /protein_id="CAC30834.1" FT /translation="MPTIQQLVRKGRRDKIGKVKTAALKGNPQRRGVCTRVYTSTPKKP FT NSALRKVARVKLTSQVEVTAYIPGEGHNLQEHSMVLVRGGRVKDLPGVRYKIIRGSLDT FT QGVKNRKQARSRYGAKKEKS" FT misc_feature complement(260814..261182) FT /note="Pfam match to entry PF00164 Ribosomal_S12, Ribosomal FT protein S12, score 265.90, E-value 5.5e-76" FT misc_feature complement(261033..261056) FT /note="PS00055 Ribosomal protein S12 signature" FT CDS complement(262503..263288) FT /pseudo FT /transl_table=11 FT /gene="ML1881" FT /product="glycosyltransferase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv2952 (Best blastx score 305)" FT CDS complement(263469..263741) FT /pseudo FT /transl_table=11 FT /gene="ML1882" FT /product="transcriptional regulator (TetR/AcrR family) FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0681 (Best blastx score 194)" FT CDS 264128..264422 FT /pseudo FT /transl_table=11 FT /gene="ML1883" FT /product="possible membrane protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0680c (Best blastx score 154)" FT CDS 264605..264954 FT /pseudo FT /transl_table=11 FT /gene="ML1884" FT /product="possible membrane protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0679c (Best blastx score 155)" FT CDS complement(264990..265750) FT /pseudo FT /transl_table=11 FT /gene="echA5" FT /gene_synonym="ML1885" FT /product="enoyl-CoA hydratase/isomerase superfamily FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT echA5 (Best blastx score 338)" FT CDS complement(265758..266518) FT /pseudo FT /transl_table=11 FT /gene="ML1886" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0674 (Best blastx score 207)" FT repeat_region 265830..266139 FT /note="310 bp repeat. Identical to region FT complement(2887367..2887676)" FT CDS complement(266654..267606) FT /pseudo FT /transl_table=11 FT /gene="echA4" FT /gene_synonym="ML1887" FT /product="enoyl-CoA hydratase/isomerase superfamily FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT echA4 (Best blastx score 408)" FT CDS complement(267621..269117) FT /pseudo FT /transl_table=11 FT /gene="fadE8" FT /gene_synonym="ML1888" FT /product="acyl-CoA dehydrogenase (aka aidB) (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT fadE8 (Best blastx score 347)" FT CDS complement(269237..269995) FT /transl_table=11 FT /gene="ML1889" FT /product="putataive endonuclease IV (apurinase)" FT /note="Similar to Mycobacterium tuberculosis probable FT endonuclease IV nfo or end or Rv0670 or MTCI376.04C FT SW:END4_MYCTU (O86366) (252 aa) fasta scores: E(): 0, 85.6% FT id in 250 aa. Similar to amny putative endonucleases. FT Previously sequenced as SW:END4_MYCLE (P30770). Contains FT Pfam match to entry PF01261 AP_endonulease2, AP FT endonuclease family 2. Contains PS00730 AP endonucleases FT family 2 signature 2. Contains PS00731 AP endonucleases FT family 2 signature 3. Contains PS00729 AP endonucleases FT family 2 signature 1." FT /db_xref="GOA:P30770" FT /db_xref="InterPro:IPR012307" FT /db_xref="UniProtKB/Swiss-Prot:P30770" FT /protein_id="CAC30843.1" FT /translation="MLIGSHVSSTDPLAAAEVEGADVVQIFLGNPQSWKAPTLRSDADV FT LKATALPVYVHAPYLINVASANSRVRIPSRKILQQTCDAAADIGAAAVVVHGGYVADDN FT DLEDGFQRWRKALDQLQTDVPVYLENTAGGDHAMARRFDTIARLWDVIGETGIGFCLDT FT CHAWAAGEGLIHVVDRIKAITGRIDLVHCNDSKDEAGSGRDRHANLGSGQIDAELLVAA FT VKVAGAPVICETAEEGRKDDIAFLREKTSG" FT misc_feature complement(269240..269977) FT /note="Pfam match to entry PF01261 AP_endonulease2, AP FT endonuclease family 2, score 448.90, E-value 4.4e-131" FT misc_feature complement(269384..269428) FT /note="PS00731 AP endonucleases family 2 signature 3" FT misc_feature complement(269501..269524) FT /note="PS00730 AP endonucleases family 2 signature 2" FT misc_feature complement(269804..269830) FT /note="PS00729 AP endonucleases family 2 signature 1" FT CDS complement(270320..274270) FT /transl_table=11 FT /gene="rpoC" FT /gene_synonym="ML1890" FT /product="[beta]' subunit of RNA polymerase" FT /note="Similar to M. tuberculosis DNA-directed RNA FT polymerase beta' chain Rv0668 SW:RPOC_MYCTU (P47769) (1316 FT aa); Fasta score E(): 0, 95.6% identity in 1316 aa overlap, FT and to many others e.g. Escherichia coli SW:RPOC_ECOLI FT (P00577) (1407 aa); Fasta score E(): 0, 42.5% identity in FT 1461 aa overlap. Contains Pfam match to entry PF00623 FT RNA_pol_A, RNA polymerase alpha subunit. Contains Pfam FT match to entry PF01854 RNA_pol_A2, RNA polymerase A/beta'/A FT subunit." FT /db_xref="GOA:P30761" FT /db_xref="HSSP:1HQM" FT /db_xref="InterPro:IPR012754" FT /db_xref="UniProtKB/Swiss-Prot:P30761" FT /protein_id="CAC30844.1" FT /translation="MLDVNFFDELRIGLATAEDIRQWSYGEVKKPETINYRTLKPEKDG FT LFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHI FT WYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITTVDEEMRHNELSTLEAEMMVERKSVE FT DQRDADLEARAQKLEADLAALEAEGAKADARRKFRDGGEREMRQLRERAQRELDRLEDI FT WSTFTKLAPKQLIVDENLYRELVDRYGEYFTGAMGAESIQKLMQDFDIEAEAESLREVI FT RNGKGQKKLRALKRLKVVAAFQQSGNSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDL FT NDLYRRVINRNNRLKRLIDLGAPDIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPL FT KSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMK FT RLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPMLV FT EGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGRPLAM FT PRLDMVTGLYYLTTAVDGDTGAYRPAAEDRPESGVYSSPAEAIMAADRGVLSVRAKIKV FT QLTQVRPPADIEARWFGANGWRPGDPWIADTTLGRVMFNELLPLGYPFVNKQMHKKVQA FT AIINDLAERYPMIVVAQTVDKLKDAGFYWATRSGVTVSMADVLVPPRKKEILDHYEERA FT DKVEKQFQRGALNHDERNEALVEIWKEATDEVGQALRDHYPVDNPIITIVDSGATGNFT FT QTRALAGMKGLVTNPKGEFIPRPVKSSFREGLTVLEYFINTHGARKGLADTALRTADSG FT YLTRRLVDVSQDVIVREHDCQTERGIVVELAVRVPDGSLIRELYIETSAYARTLGANAV FT DEAGNVIVARGEDLGDPEIDALLAAGITQVKVRSVLTCTTGTGVCATCYGRSMATGKLV FT DIGEAVGIVAAQSIGEPGTQLTMRTFHQGGVGEDITGGLPRVQELFEARVPRGKAPIAD FT VTGRVRLEDGERFYKITIVPDDGGEEVVYDKLSKRQRLRVFKHADGSERVLSDGDYVEV FT GQQLMEGSADPHEVLRVQGPREVQIHLVREVQEVYRAQGVSIHDKHIEVIVRQMLRRVT FT IIDSGSTEFLPGSLIDRAEFESENRRVVAESGEPAAGRPVLMGITKASLATDSWLSAAS FT FQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAGTGINRYRNIQVQPTEEARASAYT FT IPSYEDQYYSPDFGQATGAAVPLDDYGYSDYR" FT misc_feature complement(270473..271375) FT /note="Pfam match to entry PF01854 RNA_pol_A2, RNA FT polymerase A/beta'/A subunit, score -67.30, E-value FT 5.4e-06" FT misc_feature complement(271547..273343) FT /note="Pfam match to entry PF00623 RNA_pol_A, RNA FT polymerase alpha subunit, score 928.10, E-value 0" FT CDS complement(274319..277855) FT /transl_table=11 FT /gene="rpoB" FT /gene_synonym="ML1891" FT /product="[beta] subunit of RNA polymerase" FT /note="Similar to M. tuberculosis DNA-directed RNA FT polymerase beta chain RV0667 SW:RPOB_MYCTU (P47766) (1178 FT aa); Fasta score E(): 0, 94.9% identity in 1178 aa overlap, FT and to many others e.g. Synechocystis sp. SW:RPOB_SYNY3 FT (P77965) (1102 aa); Fasta score E(): 0, 55.0% identity in FT 1129 aa overlap. Contains Pfam match to entry PF00562 FT RNA_pol_B, RNA polymerase beta subunit. Contains PS01166 FT RNA polymerases beta chain signature." FT /db_xref="GOA:P30760" FT /db_xref="HSSP:1HQM" FT /db_xref="InterPro:IPR007641" FT /db_xref="UniProtKB/Swiss-Prot:P30760" FT /protein_id="CAC30845.1" FT /translation="MLEGCILPDFGQSKTDVSPSQSRPQSSPNNSVPGAPNRISFAKLR FT EPLEVPGLLDVQTDSFEWLIGSPCWRAAAASRGDLKPVGGLEEVLYELSPIEDFSGSMS FT LSFSDPRFDEVKAPVEECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEK FT GTFIINGTERVVVSQLVRSPGVYFDETIDKSTEKTLHSVKVIPSRGAWLEFDVDKRDTV FT GVRIDRKRRQPVTVLLKALGWTSEQITERFGFSEIMRSTLEKDNTVGTDEALLDIYRKL FT RPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHAGELITSSTLTEEDVVA FT TIEYLVRLHEGQSTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERV FT VRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSAL FT GPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIGLIGSLSVYARVNPFGFIETPYR FT KVVDGVVSDEIEYLTADEEDRHVVAQANSPIDEAGRFLEPRVLVRRKAGEVEYVASSEV FT DYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAA FT IDAGHVVVAEKSGVIEEVSADYITVMADDGTRRTYRMRKFARSNHGTCANQSPIVDAGD FT RVEAGQVIADGPCTENGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIE FT EHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAEVRDGDILVGKVTPKGET FT ELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSHEDDDELPAGVNELVRV FT YVAQKRKISDGDKLAGRHGNKGVIGKILPAEDMPFLPDGTPVDIILNTHGVPRRMNVGQ FT ILETHLGWVAKSGWKIDVAGGIPDWAVNLPEELLHAAPNQIVSTPVFDGAKEEELQGLL FT SSTLPNRDGDVMVGGDGKAVLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARSTGP FT YSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIV FT KGENIPEPGIPESFKVLLKELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINL FT SRNESASIEDLA" FT misc_feature complement(274565..277513) FT /note="Pfam match to entry PF00562 RNA_pol_B, RNA FT polymerase beta subunit, score 1756.50, E-value 0" FT misc_feature complement(275174..275212) FT /note="PS01166 RNA polymerases beta chain signature" FT CDS complement(278310..279326) FT /transl_table=11 FT /gene="ML1892" FT /product="ABC transporter ATP-binding protein" FT /note="Similar to M. tuberculosis ABC transporter Rv0655 FT SW:MKL_MYCTU (O06784) (359 aa); Fasta score E(): 0, 93.2% FT identity in 336 aa overlap, and to many others e.g. FT Escherichia coli hypothetical ABC transporter ATP-binding FT protein SW:YRBF_ECOLI (P45393) (269 aa); Fasta score E(): FT 2.4e-32, 38.9% identity in 252 aa overlap. Contains Pfam FT match to entry PF00005 ABC_tran, ABC transporter. Contains FT PS00017 ATP/GTP-binding site motif A (P-loop). Contains FT PS00211 ABC transporters family signature." FT /note="Similar to ML0669, ML1424, ML1089, ML2352, ML2189, FT ML0336, ML1122, ML1113, ML0595, ML1114, ML0590, ML1726 and FT ML1816" FT /db_xref="GOA:P30769" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/Swiss-Prot:P30769" FT /protein_id="CAC30846.1" FT /translation="MPMGVAIEVKGLTKSFGSSRIWEDVTLDIPAGEVSVLLGPSGTGK FT SVFLKSLIGLLRPERGSILIDGTDIIECSAKELYEIRTLFGVLFQDGALFGSMNLYDNT FT AFPLREHTKKKESEIRDIVMEKLQLVGLGGDEKKFPGEISGGMRKRAGLARALVLDPQI FT ILCDEPDSGLDPVRTAYLSQLIMDINAQIDATILIVTHNVNIARTVPDNMGMLFRKHLV FT MFGPREVLLTSDEPVVRQFLNGRRIGPIGMSEEKDESTMAEEAALLEAGHYAGGAEEVE FT GVPPQITVTPGMPKRKAVARRQARVRAMLPTLPKGAQAAILDDLEGAHNYQAHEFGD" FT misc_feature complement(278676..279233) FT /note="Pfam match to entry PF00005 ABC_tran, ABC FT transporter, score 164.90, E-value 1.4e-45" FT misc_feature complement(278856..278900) FT /note="PS00211 ABC transporters family signature" FT misc_feature complement(279189..279212) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(279491..280806) FT /pseudo FT /transl_table=11 FT /gene="ML1893" FT /product="putative dioxygenase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0654 (Best blastx score 240)" FT CDS 280926..281394 FT /pseudo FT /transl_table=11 FT /gene="ML1894" FT /product="putative transcriptional regulator (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0653c (Best blastx score 142)" FT CDS complement(281485..281877) FT /transl_table=11 FT /gene="rplL" FT /gene_synonym="ML1895" FT /product="50S ribosomal protein L7/L12" FT /note="Similar to M. tuberculosis 50S ribosomal protein FT L7/L12 rplL Rv0652 SW:RL7_MYCTU (P37381) (130 aa); Fasta FT score E(): 0, 88.5% identity in 130 aa overlap. Contains FT Pfam match to entry PF00542 Ribosomal_L12, Ribosomal FT protein L7/L12 C-terminal domain." FT /db_xref="GOA:P30763" FT /db_xref="HSSP:1CTF" FT /db_xref="InterPro:IPR013823" FT /db_xref="UniProtKB/Swiss-Prot:P30763" FT /protein_id="CAC30849.1" FT /translation="MSKLSSDELLDVFKEMTLLELSDFVKKFEETFEVTAAAPVSVAVA FT GAPAAGEAGEAAEEQSEFDVILESAGDKKIGVIKVVREIVSGLGLKEAKDLVDGVPKLL FT LEKVAKEAADDAKAKLEATGATVSVK" FT misc_feature complement(281488..281694) FT /note="Pfam match to entry PF00542 Ribosomal_L12, Ribosomal FT protein L7/L12 C-terminal domain, score 130.70, E-value FT 2.7e-35" FT CDS complement(281913..282446) FT /transl_table=11 FT /gene="rplJ" FT /gene_synonym="ML1896" FT /product="50S ribosomal protein L10" FT /note="Similar to M. tuberculosis 50S ribosomal protein L10 FT rplJ OR Rv0651 SW:RL10_MYCTU (P96940) (178 aa); Fasta score FT E(): 0, 89.3% identity in 178 aa overlap. Contains Pfam FT match to entry PF00466 Ribosomal_L10, Ribosomal protein FT L10." FT /db_xref="GOA:Q9CBK7" FT /db_xref="InterPro:IPR002363" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBK7" FT /protein_id="CAC30850.1" FT /translation="MARADKATAVANIAEQFKAATAALITEYRGLTVANLAELRRSLTG FT SASYAVAKNTLIKRAASEVGIEGLDELFAGPTAIAFVTGEPVDAAKAIKTFAKEHKALV FT IKGGYMDGHPMTVAEVERIADLESREVLLAKLAGAMKGTFAKAIGLFNAPTSQMARLTA FT ALQEKKAFEPASAE" FT misc_feature complement(282153..282446) FT /note="Pfam match to entry PF00466 Ribosomal_L10, Ribosomal FT protein L10, score 142.90, E-value 5.8e-39" FT CDS complement(282731..283002) FT /pseudo FT /transl_table=11 FT /gene="ML1897" FT /product="transcriptional regulator (ROK family) FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0650 (Best blastx score 139)" FT CDS 283338..284684 FT /transl_table=11 FT /gene="ML1898" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis conserved hypothetical FT protein Rv0647c SW:Y647_MYCTU (P96936) (488 aa); Fasta FT score E(): 0, 85.3% identity in 448 aa overlap, and to FT others e.g. Synechocystis sp. SW:YH70_SYNY3 (P73627) (585 FT aa); Fasta score E(): 0, 30.9% identity in 401 aa overlap." FT /note="Similar to and ML0640" FT /db_xref="GOA:Q9CBK6" FT /db_xref="InterPro:IPR004147" FT /db_xref="UniProtKB/TrEMBL:Q9CBK6" FT /protein_id="CAC30852.1" FT /translation="MSSTNNHQVVKLDRVPLPVEAARIAATYWQITRAAARVATKLAGK FT GPWQQKVIREIPQTFANLGPTYVKFGQIIASSPSAFGESLAREFRGLLDQVPPADTNEV FT HKLFVEELGDAPSKLFASFSEEPFASASIAQVHSAILHSGEHVVVKIQRPGIRRRVAAD FT LQILKRFAQAVELAKLGRRLSAQDVVADFSDNLAEELNFRLEAQSMEAWGSYLHTSPLG FT KNIRVPKVHWEFTGERVLTMEQVHGIRIDNADAIRKSGFDGVELVKALLFSVFEGGLRH FT GLFHGDLHAGNLHVDDQGRIVFFDFGIMGRIDPRTRWLLRELVFALLVKKDHAAAGKIV FT VLMGAVGTVKPEARAAKDLENFTTPLAMKTLGDMSYTDIGRQLSALSDAYNVKLPRELV FT LIGKQFLYVERYMKLLAPEWQIMLDPELTGYFANFMVEVSREHQSDVEI" FT CDS 284684..285598 FT /transl_table=11 FT /gene="lipG" FT /gene_synonym="ML1899" FT /product="probable hydrolase" FT /note="Similar to M. tuberculosis putative hydrolase FT Rv0646c TR:P96935 (EMBL:Z92772) (301 aa); Fasta score E(): FT 0, 71.3% identity in 303 aa overlap, and to others e.g. FT Escherichia coli macrolide 2'-phosphotransferase II FT TR:P77026 (EMBL:D85892) (279 aa); Fasta score E(): 1.3e-15, FT 31.3% identity in 291 aa overlap, and Streptomyces FT peucetius 10-carbomethoxy-13-deoxycarminomycin esterase FT TR:Q54809 (EMBL:L40425) (298 aa); Fasta score E(): 1e-09, FT 28.6% identity in 301 aa overlap. Contains Pfam match to FT entry PF00561 abhydrolase, alpha/beta hydrolase fold." FT /note="Similar to and ML0862" FT /db_xref="GOA:Q9CBK5" FT /db_xref="InterPro:IPR000073" FT /db_xref="UniProtKB/TrEMBL:Q9CBK5" FT /protein_id="CAC30853.1" FT /translation="MEVRSGYATSGDLKLYYEDMGNVDDPPVLLIMGLGAQLVLWRTAF FT CEKLVAQGLRVVRYDNRDVGLSSRTDSTEQPCPSQPLTARLIRFWLGQRNACAYTLEDM FT TDDAVALLDHLSIERAHIVGASMGGMIAQIFAARFPTRTRSLAVFFSSNNRPFLPPPAP FT RALLALLTGPPTGSRRDVVVDNVVRVTKITGSPLYRMPEEQVRTNAAEIYDRSFYPLGV FT SRQFSAILGSGSLLHYNQRIIAPTVVIHGRADKLVRPSSGRAVARAITGARLVLFDGMG FT HDLPQQLWDQAVGVLMSNFAKAS" FT misc_feature 284843..285586 FT /note="Pfam match to entry PF00561 abhydrolase, alpha/beta FT hydrolase fold, score 62.80, E-value 7.1e-15" FT CDS 285656..286516 FT /transl_table=11 FT /gene="mmaA1" FT /gene_synonym="ML1900" FT /product="methyl mycolic acid synthase 1" FT /note="Similar to M. tuberculosis methyl mycolic acid FT synthase 1 Rv0645C TR:P94922 (EMBL:U77466) (286 aa); Fasta FT score E(): 0, 87.4% identity in 286 aa overlap, and to many FT others e.g. M. tuberculosis FT cyclopropane-fatty-acyl-phospholipid synthase 1 FT SW:CFA1_MYCTU (Q11195) (287 aa); Fasta score E(): 0, 54.9% FT identity in 284 aa overlap." FT /note="Similar to ML2459, ML2426 and ML2334" FT /db_xref="GOA:Q9CBK4" FT /db_xref="HSSP:1KP9" FT /db_xref="InterPro:IPR003333" FT /db_xref="UniProtKB/TrEMBL:Q9CBK4" FT /protein_id="CAC30854.1" FT /translation="MAKLRPYYEESQSAYDISDDFFALFLDPTWVYTCAYFERDDMTLE FT EAQLAKLDLALDKLNLAPGMTLLDVGCGWGGALVRAVEKYDVNVIGLTLSRNHCARSKA FT RLAEILTKRHAEARLQGWEEFEEKVDRIVSFEALDAFKKERYPAFFERSYNILPDDGRM FT LLHSLFTYDRRWLHEQGIPLTMGDLRFLKFLRESIFPGGELPSQPDIVDNAEAAGFSVE FT QIQLMQPHYARTLDMWATNLAAARDHALAIQPEEIYDNFMHYLTGCADRFRRGLINVAQ FT FTLTK" FT CDS 286675..287542 FT /pseudo FT /transl_table=11 FT /gene="ML1901" FT /product="methyl mycolic acid synthase 2 (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT mmaA2" FT repeat_region 286721..286781 FT /note="61 bp repeat. 86% identical to positions FT 2932108..2932168 (53/61)" FT CDS 287701..288583 FT /pseudo FT /transl_table=11 FT /gene="ML1902" FT /product="methyl mycolic acid synthase 3 (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT mmaA3" FT RBS 288664..288668 FT /note="possible RBS" FT CDS 288681..289577 FT /transl_table=11 FT /gene="mmaA4" FT /gene_synonym="ML1903" FT /product="methyl mycolic acid synthase 4" FT /note="Similar to M. tuberculosis methyl mycolic acid FT synthase 4 Rv0642C TR:P72028 (EMBL:U66108) (301 aa); Fasta FT score E(): 0, 87.5% identity in 296 aa overlap, and to many FT others e.g. M. tuberculosis FT cyclopropane-fatty-acyl-phospholipid synthase 1 FT SW:CFA1_MYCTU (Q11195) (287 aa); Fasta score E(): 0, 57.0% FT identity in 286 aa overlap." FT /note="Similar to ML2459, ML2426 and ML2334" FT /db_xref="GOA:Q9CBK3" FT /db_xref="HSSP:1KP9" FT /db_xref="InterPro:IPR003333" FT /db_xref="UniProtKB/TrEMBL:Q9CBK3" FT /protein_id="CAC30857.1" FT /translation="MTEQPTGPTKTRTRSEDIQAHYDLSNEFFALFQDPTRTYSCAYFE FT PPDLTLEEAQYAKIDLNLNKLDLKPGMTLLDIGCGWGTTMRRAVEKYDVKVIGLTLSKN FT QHARCEQVLTALESNRSRQVRLQGWEDFTEPVDRIVSIEAFEHFGHENYDDFFKRCFNI FT MPSDGRMTVQSSVSYHPFDMAARGKKLSFETARFIKFIITEIFPGGRLPSTKMMVEHGE FT KAGFTVSEPLSLQSHYVKTLRIWGDTLESNRAKAIEVTSEAVYNRYMKYLRGCAHYFSD FT EMLDCSLVTYLKPGALD" FT CDS complement(291359..292066) FT /transl_table=11 FT /gene="rplA" FT /gene_synonym="ML1904" FT /product="50S ribosomal protein L1" FT /note="Similar to M. tuberculosis 50S ribosomal protein L1 FT RV0641 SW:RL1_MYCTU (P96932) (235 aa); Fasta score E(): 0, FT 93.6% identity in 235 aa overlap. Contains Pfam match to FT entry PF00687 Ribosomal_L1, L1P family of ribosomal FT proteins." FT /db_xref="GOA:Q9CBK2" FT /db_xref="HSSP:1AD2" FT /db_xref="InterPro:IPR016094" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBK2" FT /protein_id="CAC30858.1" FT /translation="MSKSSKAYRAAAVKVDRTNLYTPLQAAKLAKETSSTRQDATVEVA FT IRLGVDSRKADQMVRGTVNLPHGTGKTARVAVFAVGEKADVAVAAGADVVGSDDLIEKI FT QGGWLEFDAAVATPDQMAKVGRIARVLGPRGLMPNPKTGTVTPDVAKAVADIKGGKINF FT RVDKQANLHFVIGKASFDEKRLAENYGAALEEVLRLKPSSSKGRYLKKVTVSTTMGPGI FT PVDPSITRNFTEE" FT misc_feature complement(291404..292024) FT /note="Pfam match to entry PF00687 Ribosomal_L1, L1P family FT of ribosomal proteins, score 386.20, E-value 3.2e-112" FT CDS complement(292198..292626) FT /transl_table=11 FT /gene="rplK" FT /gene_synonym="ML1905" FT /product="50S ribosomal protein L11" FT /note="Similar to M. tuberculosis 50S ribosomal protein L11 FT Rv0640 SW:RL11_MYCTU (P96931) (142 aa); Fasta score E(): 0, FT 92.3% identity in 142 aa overlap. Contains Pfam match to FT entry PF00298 Ribosomal_L11, Ribosomal protein L11. FT Contains PS00359 Ribosomal protein L11 signature." FT /db_xref="GOA:Q9CBK1" FT /db_xref="HSSP:1MMS" FT /db_xref="InterPro:IPR006519" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBK1" FT /protein_id="CAC30859.1" FT /translation="MATKKKVAGLIKLQIQAGQANPAPPVGPALGQHGVNIMEFCKAYN FT AATENQRGQVIPVEITVYEDRSFTFALKTPPAAKLLLDAAGVGKGVAEPHKTKVVKVSW FT DQVREIAETKKADLNANDIDAAAKIIAGTARSMGITVE" FT misc_feature complement(292201..292245) FT /note="PS00359 Ribosomal protein L11 signature" FT misc_feature complement(292201..292596) FT /note="Pfam match to entry PF00298 Ribosomal_L11, Ribosomal FT protein L11, score 286.40, E-value 3.7e-82" FT CDS complement(292654..293340) FT /transl_table=11 FT /gene="nusG" FT /gene_synonym="ML1906" FT /product="transcription antitermination protein nusG" FT /note="Similar to M. tuberculosis transcription FT antitermination protein nusG Rv0639 TR:P96930 (EMBL:Z92772) FT (238 aa); Fasta score E(): 0, 93.4% identity in 211 aa FT overlap, and to many others e.g. Streptomyces griseus. FT Contains PS01014 Transcription termination factor nusG FT signature." FT /db_xref="GOA:Q9CBK0" FT /db_xref="HSSP:1M1G" FT /db_xref="InterPro:IPR014722" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBK0" FT /protein_id="CAC30860.1" FT /translation="MQEAGIDEFAAGGGHVEPAAEVDPAAALKAELRSKPGDWYVIHSY FT AGYENKVKANLETRVQNLDVGDCIFQVEVPTEEVTEIKNGQRRLVNRKVLPGYILVRMD FT LTDDSWAAVRNTPGVTGFVGATSRPSALALDDVVKFLLPSGSAKKDAKGAVSTAAAAEA FT GGLERSIIEVDYEVGESVTVMDGPFATLPATISEVNAEQQKLKVLVSIFGRETPVELTF FT SQVSKI" FT misc_feature complement(292681..292710) FT /note="PS01014 Transcription termination factor nusG FT signature" FT CDS complement(293418..293858) FT /transl_table=11 FT /gene="secE" FT /gene_synonym="ML1907" FT /product="SecE preprotein translocase" FT /note="Similar to M. tuberculosis preprotein translocase FT SECE subunit RV0638 SW:SECE_MYCTU (P96929) (161 aa); Fasta FT score E(): 2.2e-19, 61.3% identity in 160 aa overlap, and FT to many others e.g. Streptomyces virginiae SW:SECE_STRVG FT (P36691) (93 aa); Fasta score E(): 7.9e-08, 41.0% identity FT in 78 aa overlap. Contains Pfam match to entry PF00584 FT SecE, SecE/Sec61-gamma subunits of protein translocation FT complex. Contains PS01067 Protein secE/sec61-gamma FT signature." FT /db_xref="GOA:Q9CBJ9" FT /db_xref="InterPro:IPR005807" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBJ9" FT /protein_id="CAC30861.1" FT /translation="MSDERYAASDGGGTEVGSGTRGRTTVVTKPATRPQRPTGKRSRQR FT AANASNTGANVEVEESSTQAAIAKEGKVKKPKKSADRSANPIVFIYNYLKQVVGEMRKV FT IWPNRKQMLTYTSVVLAFLAFMVALVGLADFGLAKLVLLVFG" FT misc_feature complement(293424..293594) FT /note="Pfam match to entry PF00584 SecE, SecE/Sec61-gamma FT subunits of protein translocation complex, score 64.80, FT E-value 1.8e-15" FT misc_feature complement(293496..293582) FT /note="PS01067 Protein secE/sec61-gamma signature" FT tRNA complement(293951..294023) FT /gene="trpT" FT /note="tRNA Trp anticodon CCA, Cove score 79.38" FT CDS complement(294194..294694) FT /transl_table=11 FT /gene="ML1908" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis hypothetical protein FT Rv0637 TR:P96928 (EMBL:Z92772) (166 aa); Fasta score E(): FT 0, 88.6% identity in 166 aa overlap, and to others e.g. FT Streptomyces coelicolor SCD82.07 TR:CAB77410 FT (EMBL:AL160431) (150 aa); Fasta score E(): 4.7e-11, 29.3% FT identity in 150 aa overlap." FT /note="Similar to ML1910 and ML2425" FT /db_xref="InterPro:IPR016709" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBJ8" FT /protein_id="CAC30862.1" FT /translation="MALKTDIRGMVWRYSDYFIVGREQCREFARAIKCDHPAYFSEDAA FT AELGYDAIVAPLTFVTIFAKYVQLDFFRNVDVGMETMQIVQVDQRFVFHKPVLVGDKLW FT ARMDIHSVSERFGADIVVTKNSCTSDDGELVMEAYTTLMGQQGDNSSQLKWDKESGQVI FT RSA" FT CDS complement(294698..295126) FT /transl_table=11 FT /gene="ML1909" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis hypothetical protein FT Rv0636 TR:P96927 (EMBL:Z92772) (142 aa); Fasta score E(): FT 0, 93.0% identity in 142 aa overlap. Contains Pfam match to FT entry PF01575 MaoC_dehydratas, MaoC like domain." FT /note="Similar to and ML2566" FT /db_xref="GOA:Q9CBJ7" FT /db_xref="InterPro:IPR000169" FT /db_xref="UniProtKB/TrEMBL:Q9CBJ7" FT /protein_id="CAC30863.1" FT /translation="MARREFSSVKVGDLLPEKTYPLTRQDLVNYAGVSGDLNPIHWDDE FT IAKVVGLDTAIAHGMLTMGIGGGYVTSWVGDPGAVIEYNVRFTAVVPVPNDGQGAVLVF FT SGKVKSVDPDTKSVTIALSATTGGKKIFGRAIASAKLA" FT misc_feature complement(294743..295114) FT /note="Pfam match to entry PF01575 MaoC_dehydratas, MaoC FT like domain, score 135.20, E-value 1.2e-36" FT CDS complement(295113..295592) FT /transl_table=11 FT /gene="ML1910" FT /product="conserved hypothetical protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT proteins e.g. Rv0635 or MTCY20H10.16 TR:P96926 FT (EMBL:Z92772) (158 aa) fasta scores: E(): 0, 84.9% id in FT 159 aa. Also similar to Streptomyces coelicolor FT hypothetical protein SCD82.07 TR:CAB77410 (EMBL:AL160431) FT (150 aa) fasta scores: E(): 1.9e-11, 30.4% id in 148 aa." FT /db_xref="InterPro:IPR016709" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBJ6" FT /protein_id="CAC30864.1" FT /translation="MGLTTNIVGMHYRYPDHYEVEREKIREYAVAVQNEDTSYFEEDAA FT AELGYKGLLAPLTFICLFGYKAQSAFFKHANIAVTDQQIVQIDQVLKFVKPIVAGDKLY FT CDVYVDSMREAHGTQIIVTKNVVTNEVGDIVQETYTTLAGRVGEGGEEGFSDGAA" FT CDS complement(295639..295806) FT /transl_table=11 FT /gene="rpmG2" FT /gene_synonym="ML1911" FT /product="50S ribosomal protein L33 type 2" FT /note="Similar to M. tuberculosis 50S ribosomal protein L33 FT type 2 SW:R332_MYCTU (P96925) (55 aa); Fasta score E(): FT 5.5e-24, 92.7% identity in 55 aa overlap. Contains PS00582 FT Ribosomal protein L33 signature." FT /db_xref="GOA:Q9CBJ5" FT /db_xref="InterPro:IPR018264" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBJ5" FT /protein_id="CAC30865.1" FT /translation="MASSTDVRPKITMACEVCKHRNYITKKNRRNDPDRMELKKFCRNC FT GKHQSHRETR" FT misc_feature complement(295681..295740) FT /note="PS00582 Ribosomal protein L33 signature" FT tRNA complement(295850..295926) FT /gene="metT" FT /note="tRNA Met anticodon CAT, Cove score 89.68" FT tRNA complement(295980..296052) FT /gene="thrT" FT /note="tRNA Thr anticodon GGT, Cove score 79.74" FT CDS complement(296206..296421) FT /transl_table=11 FT /gene="ML1911A" FT /product="conserved hypothetical protein" FT /note="Orthologous to M. tuberculosis Rv0634A but may be FT pseudogene as Rv0634A is predicted to be 13 aa longer. Also FT similar to M. tuberculosis Rv1560, sp|Q10771|YF60_MYCTU FT HYPOTHETICAL 8.2 KDA PROTEIN RV1560 (72 aa) E(): 0.0025; FT 47.500% identity in 40 aa overlap" FT /db_xref="InterPro:IPR019239" FT /db_xref="UniProtKB/TrEMBL:Q7AQ19" FT /protein_id="CAC30866.1" FT /translation="MLKKVEIEVDDDLVQEVIRRYGLLGRREAVHLALKALLGEPGVGG FT LSEQDPEYDEFSNPDAWRTRRSSDTG" FT CDS 296574..297290 FT /transl_table=11 FT /gene="ML1912" FT /product="putative glyoxylase II" FT /note="Similar to M. tuberculosis putative glyoxylase II FT Rv0634c, to hypothetical proteins belonging to the FT glyoxalase II family e.g. Escherichia coli SW:YCBL_ECOLI FT (P75849) (215 aa); Fasta score E(): 3.5e-12, 32.5% identity FT in 203 aa overlap. Contains Pfam match to entry PF00753 FT lactamase_B, Metallo-beta-lactamase superfamily." FT /note="Similar to ML0493, ML2303 and ML1391" FT /db_xref="GOA:Q9CBJ4" FT /db_xref="HSSP:1QH5" FT /db_xref="InterPro:IPR001279" FT /db_xref="UniProtKB/TrEMBL:Q9CBJ4" FT /protein_id="CAC30867.1" FT /translation="MSDSDRLYFRQLLSGRDFAVDDVVATQMRNFAYLIGDRQTGDCVV FT VDPAYAAGDLVDALEADGMRLSGVLVTHHHPDHVGGVMMGFQLKGLTELLERVTVPVHV FT NTHEALWISRVTGIDIGHLTTHEHRDKLSVGDIEIELLHTPGHTPGSQCFLLDGLLVAG FT DTLFLEGCGRTDFPGGNSDEMYRSLQQLAQLPGNPTVFPGHWYSTAPSATLSMVKCSNY FT VYRAADLNQWRMLMDS" FT misc_feature 296646..297185 FT /note="Pfam match to entry PF00753 lactamase_B, FT Metallo-beta-lactamase superfamily, score 149.50, E-value FT 5.7e-41" FT CDS 297479..298173 FT /pseudo FT /transl_table=11 FT /gene="echA3" FT /gene_synonym="ML1913" FT /product="enoyl-CoA hydratase/isomerase superfamily FT (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT echA3 (Best blastx score 350)" FT CDS 298509..298992 FT /pseudo FT /transl_table=11 FT /gene="lpqN" FT /gene_synonym="ML1914" FT /product="equivalent to MKU20446_1 MK35 (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT lpqN (Best blastx score 198)" FT CDS 299521..299865 FT /transl_table=11 FT /gene="ML1915" FT /product="hypothetical protein" FT /note="unknown." FT /db_xref="UniProtKB/TrEMBL:Q9CBJ3" FT /protein_id="CAC30870.1" FT /translation="MLNPIQNWFTSYGALAAGVATPQQTDQVARILAEVECHFIITEHS FT GHTDEQDDALTRIAEAMAASVFEFMSRVYQQFPRCHPLYGAGPVKAVVDDVNAILLTGR FT QFTLTSAGPQ" FT CDS 300966..301440 FT /pseudo FT /transl_table=11 FT /gene="ML1916" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0580c (Best blastx score 335)" FT repeat_region complement(301604..302297) FT /note="Dispersed repeat, RLEP, copy 31" FT CDS 302227..302844 FT /pseudo FT /transl_table=11 FT /gene="ML1917" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv3586 (Best blastx score 150)" FT CDS complement(302885..303676) FT /transl_table=11 FT /gene="ML1918" FT /product="conserved hypothetical membrane protein" FT /note="Similar to M. tuberculosis hypothetical protein FT Rv3587c TR:O53572 (EMBL:AL022075) (264 aa); Fasta score FT E(): 0, 77.5% identity in 267 aa overlap. Contains probable FT transmembrane domain." FT /db_xref="UniProtKB/TrEMBL:Q9CBJ2" FT /protein_id="CAC30873.1" FT /translation="MLDLEPRGPLPTEIYWRRRGLAVGITVIVIVIAAIVAVVGNGAAA FT QPANVDKPGSSQNHPGSATPKVLPPNGHEGNLAPAPPQGRNPESSTSTAAVQPPPVLRE FT GDDCPDSTLAVKGLTNVPQYFLGDQPKFTMVVTNIGLVSCKRDVGAAVLAAYVYSLDNK FT RLWSNLDCAPSNETLVKTFTPGEQVTTAVTWTGMGSSPHCPLPRPAIGPGTYNLVVQLG FT NLHSMPVPFILNQPPPPPGSSGPALAPSPEAPPANVPVSGG" FT CDS complement(303815..304456) FT /transl_table=11 FT /gene="ML1919" FT /product="putative carbonic anhydrase" FT /note="Similar to M. tuberculosis putative carbonic FT anhydrase Rv3588c TR:O53573 (EMBL:AL022075) (207 aa); Fasta FT score E(): 0, 84.5% identity in 207 aa overlap, and to FT others e.g. Chlamydomonas reinhardtii carbonic anhydrase FT precursor TR:Q39589 (EMBL:U41189) (267 aa); Fasta score FT E(): 7.9e-19, 34.4% identity in 192 aa overlap. Contains FT Pfam match to entry PF00484 Pro_CA, Prokaryotic-type FT carbonic anhydrases. Contains PS00704 Prokaryotic-type FT carbonic anhydrases signature 1. Contains PS00705 FT Prokaryotic-type carbonic anhydrases signature 2." FT /db_xref="GOA:Q9CBJ1" FT /db_xref="InterPro:IPR015892" FT /db_xref="UniProtKB/TrEMBL:Q9CBJ1" FT /protein_id="CAC30874.1" FT /translation="MFNTNPIAAWKALKEGNERFVAGQPAHPSQSVEHRASLADTQKPL FT AVIFGCADSRVAAELVFDQGLGDMFVVRTVGHVIDSAVLGSIEYAVTVLDVPLVVVLGH FT DSCGAVTAALAAINEGNLPSGYVRDVVERVAPSVLLGRRDGLTRVDEFEERHVHETVAQ FT AMARSTAIAQRVAAGTLAIVGVTYHLADGRAVLRTHIGNLGEEVQLSHCS" FT misc_feature complement(304112..304345) FT /note="Pfam match to entry PF00484 Pro_CA, Prokaryotic-type FT carbonic anhydrases, score 66.00, E-value 4.1e-18" FT misc_feature complement(304133..304195) FT /note="PS00705 Prokaryotic-type carbonic anhydrases FT signature 2" FT misc_feature complement(304283..304306) FT /note="PS00704 Prokaryotic-type carbonic anhydrases FT signature 1" FT CDS 304455..305348 FT /transl_table=11 FT /gene="mutY" FT /gene_synonym="ML1920" FT /product="probable DNA glycosylase" FT /note="Similar to M. tuberculosis probable DNA glycosylase FT Rv3589 TR:O53574 (EMBL:AL022075) (304 aa); Fasta score E(): FT 0, 74.9% identity in 303 aa overlap, and to many others FT e.g. Escherichia coli A/G-specific adenine glycosylase mutY FT SW:MUTY_ECOLI (P17802) (350 aa); Fasta score E(): 1.8e-21, FT 33.2% identity in 244 aa overlap. Contains Pfam match to FT entry PF00730 Endonuclease_3, Endonuclease III." FT /note="Similar to and ML2301" FT /db_xref="GOA:Q9CBJ0" FT /db_xref="HSSP:1KG5" FT /db_xref="InterPro:IPR003651" FT /db_xref="UniProtKB/TrEMBL:Q9CBJ0" FT /protein_id="CAC30875.1" FT /translation="MAHIVPQIKISTGGLLDWYRQSCRDLPWRQPGVTAWQILVSEFML FT QQTPVARVLSIWPDWVQRWPTPSTTAAASAADVLRAWGKLGYPRRAKRLHESATIIARE FT HDDVVPDDVDVLLTMPGIGSYTARAVACFAYHQPVPVVDTNVRRVVARAVHGRADAGPP FT SATRDHADVSSLLPGKKAAPQFSMALMELGAIVCTARSPRCGLCPLNECAWRHAGYPPA FT QGPARRAQQYAGTDRQVRGLLLDVLRAKDSPVTGTELNVTWLTNSIQLDRALDSLLADG FT LVTRTTDGRFALTGEG" FT misc_feature 304560..305093 FT /note="Pfam match to entry PF00730 Endonuclease_3, FT Endonuclease III, score 143.40, E-value 4e-39" FT CDS complement(305357..306127) FT /transl_table=11 FT /gene="ML1921" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis conserved hypothetical FT protein Rv3591c TR:O06157 (EMBL:Z95555) (257 aa); Fasta FT score E(): 0, 79.0% identity in 248 aa overlap." FT /note="Similar to and ML2269" FT /db_xref="InterPro:IPR000073" FT /db_xref="UniProtKB/TrEMBL:Q9CBI9" FT /protein_id="CAC30876.1" FT /translation="MSTNLLTLRGGRGKPLILVHGLMGRGNTWSRQLPWLSQLGTVYTY FT DAPWHRGRNVVDPYPISTERFVTDLADAVSTLGVPARLVGHSMGAMHSWCLAAERPDLV FT SALVVEDMAPDFRGCSTGPWEPWLRGIPVEFDSVEKVFDEFGPVAGQYFLDAFDRTSTG FT WQLHGHTSRWIEIAAEWGTRDYWEHWLAVRSPVLLIEAGTSVTPHGQMLAMTKTACRTT FT YLYVPEAGHLIHDEATQVYRQAVVSFLAGCAGRD" FT CDS 306253..306570 FT /transl_table=11 FT /gene="ML1922" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis conserved hypothetical FT protein Rv3592 TR:O06156 (EMBL:Z95555) (105 aa); Fasta FT score E(): 0, 84.6% identity in 104 aa overlap, and to FT others e.g. Bacillus subtilis hypothetical protein FT SW:YHGC_BACSU (L10630) (166 aa); Fasta score E(): 5.2e-06, FT 40.8% identity in 71 aa overlap." FT /db_xref="GOA:Q9CBI8" FT /db_xref="InterPro:IPR007138" FT /db_xref="UniProtKB/TrEMBL:Q9CBI8" FT /protein_id="CAC30877.1" FT /translation="MPVVKINAIEVSTDVGLELERRFAHRAHAVENSPGFLGFQLLRPI FT KGENRYFVVTHWESDEAFQAWANGPAIEAHAGHSANPVAAGSSLLEFEVVLDVATTSQT FT N" FT CDS 306545..307909 FT /transl_table=11 FT /gene="lpqF" FT /gene_synonym="ML1923" FT /product="probale secreted protein" FT /note="Similar to M. tuberculosis lipoprotein Rv3593 lpqF FT TR:O06155 (EMBL:Z95555) (452 aa); Fasta score E(): 0, 79.2% FT identity in 451 aa overlap, and weakly to several FT beta-lactamase proteins e.g. Xanthomonas maltophilia FT chromosomic class A beta-lactamase TR:Q9X5A7 FT (EMBL:AF123246) (304 aa); Fasta score E(): 0.019, 26.2% FT identity in 260 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9CBI7" FT /protein_id="CAC30878.1" FT /translation="MPQPARRTNQRPPRHRTVALAATAALVVTMAPGCAHSASPYANTA FT DPGLRIDTRTPPGVRAQQIIDMLNSDWPIGLVGVRTFASHDMVEIVKTTLEELWWDRPF FT TLEGVDIGASVATLHLISSYGAQQDIRIHTDGNSWVDRFDLNTQPPSITSWYDIDAALS FT KTGARYSYQVAKVDNGRCDPVQGTNTAESLPLASIFKLYVLHALAYAVRNGTVSWDDQL FT TVTDKSRAVGSSGLELPIGEHVSVRTAAEKMIATSDNMATDLLIGKMGTHAVEEALVTA FT GHHDPASMTPFPTMYELFSVGWGQPDLRSQWKQASQQLRAQLLQQANSTPYQPDPTRAH FT TPASNYGAEWYGSAEDICRIHAALQADAIGQAAPVRQILSAVAGIQLDRSKWPYIGAKA FT GGLPGDLTFSWYAVDKTQQSWVVSFQLNWPRDHGPTVTSWMLQLAKQVFALFAPR" FT repeat_region 309977..310740 FT /note="Dispersed repeat, RLEP, copy 32" FT CDS complement(310756..311776) FT /pseudo FT /transl_table=11 FT /gene="ML1924" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0433 (Best blastx score 802)" FT CDS complement(311821..312543) FT /transl_table=11 FT /gene="sodC" FT /gene_synonym="ML1925" FT /product="superoxide dismutase precursor (Cu-Zn)" FT /note="Similar to M. tuberculosis superoxide dismutase FT precursor (Cu-Zn) Rv0432 TR:P96278 (EMBL:Z84724) (240 aa); FT Fasta score E(): 0, 72.0% identity in 239 aa overlap, and FT weakly similar to many others e.g. Photobacterium FT leiognathi superoxide dismutase SW:SODC_PHOLE (P00446) (173 FT aa); Fasta score E(): 0.0018, 29.6% identity in 189 aa FT overlap. Contains Pfam match to entry PF00080 sodcu, FT Copper/zinc superoxide dismutase (SODC). Contains PS00013 FT Prokaryotic membrane lipoprotein lipid attachment site." FT /db_xref="GOA:Q9CBI6" FT /db_xref="HSSP:1OZU" FT /db_xref="InterPro:IPR001424" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBI6" FT /protein_id="CAC30880.1" FT /translation="MSKLAGHRNVAAVTRSALSLSFVAACVALLSACIQNQPPATLPGT FT TPTVWTGSPAPSGMLGAEAESMGPPNIITRLNAPDGTQVATAKFEFNNGFATITIATTG FT VGHLAPGFHGVHIHKVGKCEPSSAGPTGGAPGDFLSAGGHFQVPGHTVEPASGNLTSLQ FT VRKDGIGTLVTTTDAFTMNDLLAGQKTAIIIHAGADNFGNIPPERYSQVNGTPGPDATT FT ISTGDAGKRVACGVIGAD" FT misc_feature complement(311830..311874) FT /note="Pfam match to entry PF00080 sodcu, Copper/zinc FT superoxide dismutase (SODC), score 12.50, E-value 0.0067" FT misc_feature complement(312466..312498) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site" FT CDS complement(312608..313111) FT /transl_table=11 FT /gene="ML1926" FT /product="tuberculin related peptide (AT103)" FT /note="Similar to M. tuberculosis tuberculin related FT peptide (AT103) Rv0431 TR:P96277 (EMBL:Z84724) (164 aa); FT Fasta score E(): 1.6e-32, 67.5% identity in 163 aa overlap FT and TR:O69619 (EMBL:D00815) (172 aa); Fasta score E(): FT 1.5e-32, 67.1% identity in 164 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9CBI5" FT /protein_id="CAC30881.1" FT /translation="MVDTVGLVNKCVPDSSGLPLRAMVMVLLFLGVIFLLLGWQALGSS FT GNSDDYSALPMSSMPNTPTTPAATSTSSTSAANQAEVRVYNISSKEGIAARTRDQLTTA FT GFKVTEVDNLVVSDVSATTVYYSDAEGEYATADAVGQKLGAPVEPRIAAITNQPPGVIV FT LVTS" FT CDS complement(313142..313450) FT /transl_table=11 FT /gene="ML1927" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis hypothetical protein FT Rv0430 TR:P96276 (EMBL:Z84724) (102 aa); Fasta score E(): FT 0, 93.1% identity in 102 aa overlap, and to Streptomyces FT coelicolor hypothetical protein SCD95A.20 TR:CAB93047 FT (EMBL:AL357432) (84 aa); Fasta score E(): 4.1e-11, 52.8% FT identity in 72 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9CBI4" FT /protein_id="CAC30882.1" FT /translation="MDGAMARAHRAGDDVEIVDGLTRREHDILAFERQWWKFAGVKEEA FT IKELFSMSATRYYQVLNALVDRPEALAVDPMLVKRLRRLRASRQKARAARRLGFEVT" FT CDS complement(313481..313618) FT /transl_table=11 FT /gene="ML1928" FT /product="hypothetical protein" FT /note="Unknown function." FT /db_xref="UniProtKB/TrEMBL:Q9CBI3" FT /protein_id="CAC30883.1" FT /translation="MADDLFEHSKQVGRLAGLGYVLILAGMIKCAPRHAFMWVKSHQAI FT " FT CDS 313665..314258 FT /transl_table=11 FT /gene="def" FT /gene_synonym="ML1929" FT /product="polypeptide deformylase" FT /note="Similar to M. tuberculosis polypeptide deformylase FT Rv0429C SW:DEF_MYCTU (P96275) (197 aa); Fasta score E(): 0, FT 83.7% identity in 196 aa overlap, and to many others e.g FT Streptomyces coelicolor polypeptide deformylase FT SW:DEF_STRCO (Q9XAQ2) (208 aa); Fasta score E(): 5.9e-20, FT 43.8% identity in 176 aa overlap. Contains Pfam match to FT entry PF01327 Pep_deformylase, Polypeptide deformylase." FT /db_xref="GOA:Q9CBI2" FT /db_xref="HSSP:1N5N" FT /db_xref="InterPro:IPR000181" FT /db_xref="UniProtKB/Swiss-Prot:Q9CBI2" FT /protein_id="CAC30884.1" FT /translation="MAIAPIRIVGDPVLHTPTAPVQVAADGSLPANLNGLISTMYDTMD FT AAHGVGLAANQIGYGLRVFVYDCAEDCRQTARRRGVVINPILETSEIPETMPDPDTDNE FT GCLSVPGESFPIGRAQWARVTGLDADGNPVTTEGTGLFARMLQHETGHLDGFLYLDYLI FT GRHARSAKRAIKSRHWGVPGLSWMPGEVPDPFGP" FT misc_feature 313677..314138 FT /note="Pfam match to entry PF01327 Pep_deformylase, FT Polypeptide deformylase, score 229.70, E-value 4.3e-65" FT CDS 314308..314713 FT /pseudo FT /transl_table=11 FT /gene="ML1930" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0428c (Best blastx score 239)" FT CDS 314769..315601 FT /pseudo FT /transl_table=11 FT /gene="xthA" FT /gene_synonym="ML1931" FT /product="exodeoxyribonuclease III (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT xthA (Best blastx score 398)" FT CDS 315871..316284 FT /transl_table=11 FT /gene="ML1932" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis hypothetical protein FT Rv0426c TR:P96272 (EMBL:Z84724) (147 aa); Fasta score E(): FT 1.6e-22, 60.4% identity in 139 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9CBI1" FT /protein_id="CAC30887.1" FT /translation="MGRGLGKAVSRAAIATTAAAGAVGGAAVNSIVGGVTGAAEGVKRG FT IRTGRHSTSTAALVLGALGVAGLVEWPILLAVGGGALLLSKMRPIPDPAAPEAKAKLKP FT VPTNSTQRKSTSKPAAKKTTRRRTATTELQGTN" FT CDS 316529..320528 FT /pseudo FT /transl_table=11 FT /gene="ctpH" FT /gene_synonym="ML1933" FT /product="putative cation-transporting (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT ctpH (Best blastx score 523)" FT CDS 320622..320861 FT /pseudo FT /transl_table=11 FT /gene="ML1934" FT /product="hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT Rv0424c (Best blastx score 230)" FT CDS complement(321126..322140) FT /pseudo FT /transl_table=11 FT /gene="PPE" FT /gene_synonym="ML1935" FT /product="PPE-family protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis orthologue FT PPE (Best blastx score 197)" FT CDS complement(323249..324319) FT /transl_table=11 FT /gene="ML1936" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis conserved hypothetical FT protein Rv1112 TR:O53459 (EMBL:AL021897) (357 aa); Fasta FT score E(): 0, 85.9% identity in 354 aa overlap, and to many FT others e.g. Haemophilus influenzae probable GTP-binding FT protein SW:YCHF_HAEIN (P44681) (362 aa); Fasta score E(): FT 0, 53.8% identity in 355 aa overlap. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop)." FT /note="Similar to and ML1465" FT /db_xref="GOA:Q9X779" FT /db_xref="HSSP:1JAL" FT /db_xref="InterPro:IPR013029" FT /db_xref="UniProtKB/TrEMBL:Q9X779" FT /protein_id="CAC30891.1" FT /translation="MSLSLGIVGLPNVGKSTLFNALTRSNVVVANYPFATIEPNEGVVS FT LPDPRLAKLAELFGSERILPAQVTFVDIAGLVKGASEGAGLGNKFLAHIRECDAICQVV FT RVFSGDDITHVTGRVDPQSDIGIIDTELILADLDTLERALPRLEKEARNHKERKPIYAA FT AINAQQVLNVGTTLFAAGVDGSALRELNLLTNKPFLYVFNADEAVLTAAAWVAELRQLV FT APADAVFLDAAIEAELAELDDESAAELLESIGQTERGLDALARAGFRTLALQTFLTVGP FT KEVRAWTIHQGDTASKAAGVIHTDFEKRFIKAEIVSYDDLIATGSMSAAKAAGKVRTEG FT KDYVMADGDVVEFRHG" FT misc_feature complement(324272..324295) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 324370..325602 FT /transl_table=11 FT /gene="ML1937" FT /product="probable integral membrane protein" FT /note="Similar to M. tuberculosis hypothetical protein FT Rv1111c TR:O86351 (EMBL:AL021897) (304 aa); Fasta score FT E(): 5.6e-31, 45.7% identity in 374 aa overlap. The FT N-terminus contains possible membrane spanning hydrophobic FT domains." FT /db_xref="UniProtKB/TrEMBL:Q9CBI0" FT /protein_id="CAC30892.1" FT /translation="MERPNEYMARQRSILNKVFTGFSAYCRYGQHVSKQQARSTVESTY FT RSILPNIPGVPWWAALLIATTASAIGYAIDAGNTDLTTVFTGFYITGCVAAVLAVRQSG FT LFTAVIQPPLILFCAVPAAYWLFHGSKIKSLKDLLINCGYPLIERFPLMLGTAGSVLLI FT GLVRWFFQLMYRTTASSNSEDDTVSKPNSLISGITAVLNSILCIYSNDQNHRANQDTAD FT TELMHSDPPLRTRQTARDNRSARTHSGQARRVVEYTSEPLVEPWQHSSQRSSEQARDFD FT AGESPRRSRRQPTPQSDPELRSQPPREIRRDAYGHRSGPYEWPTNHSSHLEPYRRYKQP FT GPPEHFTEHGQLYERYKQPRRRATPPRASSVNPISQVRYRGSTARDDPRVDRQRSQTPR FT RPVTESWEFDV" FT CDS complement(325613..326620) FT /transl_table=11 FT /gene="lytB2" FT /gene_synonym="ML1938" FT /product="LytB homolog" FT /note="Similar to M. tuberculosis LytB protein homolog FT lytB2 Rv1110 SW:LYB1_MYCTU (O53458) (335 aa); Fasta score FT E(): 0, 82.9% identity in 333 aa overlap, and to many FT others e.g. Escherichia coli LytB protein SW:LYTB_ECOLI FT (P22565) (316 aa); Fasta score E(): 0, 51.5% identity in FT 309 aa overlap." FT /db_xref="GOA:Q9X781" FT /db_xref="InterPro:IPR003451" FT /db_xref="UniProtKB/Swiss-Prot:Q9X781" FT /protein_id="CAC30893.1" FT /translation="MKGMPPTVNMGIPGASRSIVENLKRKRVLLAEPRGYCAGVDRAVE FT TVERSLRKYGPPVYVRHEIVHNRHVVETLERAGAVFVEETDYVPEGAIVIFSAHGVAPT FT VYAAAAERNLRTIDATCPLVTKVHNEVKRFARNDYDILLIGHEGHEEVIATAGEAPTHV FT QLVDGLAAVQQVVVRDENKVVWLSQTTLSVDETMRIVERLRQRFPKLQDPPSDDICYAT FT QNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVAMGSGAGAAYLVDWAKDIDPAWLAG FT VTTVGVTSGASVPDILVQGVLKWLAERGYDVVQSVTTANEALVFALPREIRSAH" FT CDS 326789..327406 FT /transl_table=11 FT /gene="ML1939" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis hypothetical protein FT Rv1109c." FT /db_xref="UniProtKB/TrEMBL:Q9X782" FT /protein_id="CAC30894.1" FT /translation="MATAPYGVRLLVGAATVAVEETLKLPRTVLMCPMTLASQVAHIVM FT RFQQNLAGLVTKGDGTLETLFPAKSEQPEWATFDEDLTDTVDETPTPLPVGDVIEIDCR FT SEERFALYSVSDTSEPEDADSLTQSMPTRHVKKAAAKLMVHAPEVADDIDYPALTLAQL FT RGKLQSLDLGELEALLVYEQATKARAPFQTLLANRITSTTAK" FT CDS 327403..328689 FT /transl_table=11 FT /gene="xseA" FT /gene_synonym="ML1940" FT /product="exonuclease VII large subunit" FT /note="Similar to M. tuberculosis exonuclease VII large FT subunit xseA Rv1108c, and to many others e.g. Escherichia FT coli exodeoxyribonuclease large subunit SW:EX7L_ECOLI FT (P04994) (456 aa); Fasta score E(): 1.7e-28, 31.8% identity FT in 425 aa overlap." FT /db_xref="GOA:Q9X783" FT /db_xref="InterPro:IPR004365" FT /db_xref="UniProtKB/Swiss-Prot:Q9X783" FT /protein_id="CAC30895.1" FT /translation="MTEAVPTDSVDSKASSQVNSAENPFPVRAVALRIAGWIDKLGTVW FT VEGQLAQITMRPNAKTVFMVLRDPAADISLIVTCSRDFVLRAPVKLAEGIQVVVCGKPS FT FYIGRGTFSLRLSDIRAVGIGELLVRIDRLRRLLDSEGLFDPRLKRPIPFLPNMIGIIT FT GRASAAERDVTTVASARWPAARFAIRNTAVQGPNAVSQIVEALRELDRNVDVEVIVVAR FT GGGSVEDLLTFSDETLCRAIAACRTPVISAVGHEPDNPLCDLVADLRAATPTDAAKKVV FT PDAAVEQRLIEDLQRRSAQALRNWVSREQRTLVQLRSRPVLAEPLRTLTTRSEEIHRAQ FT SAIRREIIRLVTTETERVGHLATQLATLGPAATLARGYAIVQALEDGTQTVTAAVLRSV FT DDAPTGTRLRVRVSDGAIVAVSEGRADGP" FT CDS 328679..328942 FT /transl_table=11 FT /gene="xseB" FT /gene_synonym="ML1941" FT /product="exonuclease VII small subunit" FT /note="Similar to M. tuberculosis exonuclease VII small FT subunit xseB Rv1107c, and to many others e.g. Escherichia FT coli exodeoxyribonuclease large subunit SW:EX7S_ECOLI FT (P22938) (79 aa); Fasta score E(): 0.021, 41.8% identity in FT 55 aa overlap." FT /db_xref="GOA:Q9X784" FT /db_xref="InterPro:IPR003761" FT /db_xref="UniProtKB/Swiss-Prot:Q9X784" FT /protein_id="CAC30896.1" FT /translation="MVPEDDTAAMRSTTPINTTPINQLGYEACRDELIEVVRLLEQGGL FT NLDMSLKLWERGEQLAKRCEEHLDGARQRVADVLSARQVEEA" FT CDS 328993..330123 FT /transl_table=11 FT /gene="ML1942" FT /product="probable cholesterol dehydrogenase" FT /note="Similar to M. tuberculosis cholesterol dehydrogenase FT Rv1106c TR:O53454 (EMBL:AL021897) (370 aa); Fasta score FT E(): 0, 75.5% identity in 375 aa overlap, and to Nocardia FT sp NAD(P)-dependent cholesterol dehydrogenase TR:Q03704 FT (EMBL:D90244) (364 aa); Fasta score E(): 0, 71.0% identity FT in 366 aa overlap. Contains Pfam match to entry PF01073 FT 3Beta_HSD, 3-beta hydroxysteroid dehydrogenase/isomerase FT family." FT /note="Similar to ML0204 and ML1964" FT /db_xref="GOA:Q9X785" FT /db_xref="HSSP:1GY8" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q9X785" FT /protein_id="CAC30897.1" FT /translation="MLRGVGNASLTTELGRVLVTGGSGFVGANLVTALLERGYQVRSFD FT RAPMPLPQHPQLEVLQGDITDATVCTTAMDSIDTVFHTAAIIELMGGASVTDEYRQRSY FT TVNVGGTENLLRAGQKSGVKRFVYTASNSVVMGGTPITGGDETMPYTKRFNDLYTETKV FT VAEKFVLSQNGVPDGETMLTCSIRPSGIWGRGDQTMFRKAFESVVSGHVKVLIGSKNAK FT LDNSYVHNLVHGLILAAEHLVPGGTAPGQAYFINDGEPINFFDFMGPIIKACGENWPRV FT RISGRLVRNVMAVWQRLHFGFGLPKPPMEPLAVERVYLDNYFSIEKAHKELGYRPLFTT FT EQAMAECLPYYTELFEQIKVAAKPHLASIAATPRPE" FT misc_feature 329005..330057 FT /note="Pfam match to entry PF01073 3Beta_HSD, 3-beta FT hydroxysteroid dehydrogenase/isomerase family, score FT 473.60, E-value 1.6e-138" FT repeat_region 330168..331038 FT /note="871 bp repeat, 100% identical to region FT 1212166..1213036" FT CDS complement(330196..330940) FT /pseudo FT /transl_table=11 FT /gene="ML1943" FT /product="conserved hypothetical protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv3714c" FT repeat_region complement(331039..331083) FT /note="45 bp REPLEP-associated sequence" FT repeat_region 331039..331999 FT /note="REPLEP region 13, 5'-end most similar to REPLEP 9; FT 3'-end most similar to REPLEP 3 and 14" FT repeat_region 331084..331957 FT /note="Dispersed repeat, REPLEP, copy 13" FT CDS complement(331914..332287) FT /pseudo FT /transl_table=11 FT /gene="ML1944" FT /product="possible IS1081 transposase (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv3023c (Best blastx score 63)" FT repeat_region 331958..331985 FT /note="28 bp subsequence of 45 bp REPLEP-associated FT sequence" FT CDS complement(332826..333599) FT /transl_table=11 FT /gene="ML1945" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis conserved hypothetical FT protein Rv1100 TR:O53448 (EMBL:AL021897) (233 aa); Fasta FT score E(): 0, 63.8% identity in 257 aa overlap." FT /db_xref="UniProtKB/TrEMBL:Q9X787" FT /protein_id="CAC30900.1" FT /translation="MVNDCPRSRSATWSWALAVNQQGWDTRRVTFEWQPNSEVANKPGS FT VSWSAKPRLLQDGRDMFWSLVPLVVGCILLAGMAGTCTFAPGGTTKSTVSSYDAAAALR FT ADARALGFPVRLPELPTGWRSNSGSRGSIEDGRMDLSTGKRLPAVTSTVGYITPTGMYL FT SLTQSNADEDRLVASIHPSSHPTGTVDVAGTKWVVYQGSDQKKDHSGAAAEPVWTSRFA FT SPVGAAQIAITGAGCSSQFRMLASATQSQQPLPAR" FT CDS 333679..334665 FT /transl_table=11 FT /gene="ML1946" FT /product="conserved hypothetical protein" FT /note="Similar to M. tuberculosis conserved hypothetical FT protein RV1099C TR:O53447 (EMBL:AL021897) (328 aa); Fasta FT score E(): 0, 93.0% identity in 328 aa overlap, and to many FT others of the glpX family e.g. Escherichia coli GLPX FT protein SW:GLPX_ECOLI (P28860) (336 aa); Fasta score E(): FT 0, 41.7% identity in 321 aa overlap." FT /db_xref="GOA:Q9CBH9" FT /db_xref="HSSP:1NI9" FT /db_xref="InterPro:IPR004464" FT /db_xref="UniProtKB/TrEMBL:Q9CBH9" FT /protein_id="CAC30901.1" FT /translation="MELVRVTEAGAMAAGRWVGRGNKEGGDGAAVDTIRELVNTVSMRG FT VVVIGEGEKDHAPMLYNGEEVGNGDGPDCDFAVDPIDGTTLMSKGMPNAISVLAVADRG FT AMFDPSAVFYMNKITVGPDAAHVLDITAPIGENIRAVAKVKDLSVRDMTVCILDRPRHA FT QLIDDVRATGARIRLITDGDVAGAISACRPQSGTDMLAGIGGTPEGIIAAAAIRCMGGA FT IQAQLAPRDDVERRKALDAGYNLDRILTTEDLVSGENVFFCATGVTDGDLLKGVRYYAG FT GCTTQSIVMRSKSGTVRMIEAYHRLSKLNEYSAIDFTGDNNAAYPLP" FT CDS 334674..336098 FT /transl_table=11 FT /gene="fum" FT /gene_synonym="ML1947" FT /product="fumarase" FT /note="Similar to M. tuberculosis fumarase Rv1098c fum FT TR:O53446 (EMBL:AL021897) (474 aa); Fasta score E(): 0, FT 89.5% identity in 467 aa overlap, and to many others e.g FT Homo sapiens fumarate hydratase, mitochondrial precursor FT SW:FUMH_HUMAN (P07954) (510 aa); Fasta score E(): 0, 52.1% FT identity in 461 aa overlap. Contains Pfam match to entry FT PF00206 lyase_1, Lyase. Contains PS00163 Fumarate lyases FT signature." FT /note="Similar to ML1413 and ML2230" FT /db_xref="GOA:Q9X789" FT /db_xref="HSSP:1YFM" FT /db_xref="InterPro:IPR018951" FT /db_xref="UniProtKB/TrEMBL:Q9X789" FT /protein_id="CAC30902.1" FT /translation="MKRTQFMADSAEYRIEHDTMGEVRVPAIALWRAQTQRAVENFPIS FT GRGLERTQIRALGLLKGACAQVNKDLGLLASEKANAIIAAAATIADGYHDDQFPIDVFQ FT TGSGTSSNMNTNEVIGSIAAANGVPVHPNDDVNMSQSSNDTFPTATHIAATEAAVRHLI FT PALQELHAALATKSSEWHTVVKSGRTHLMDAVPVTLGQEFGGYARQIEAGIERVRATLP FT RLGELAIGGTAVGTGLNAPDGFGAKVVEALIATTGLTELRPAANSFEAQAARDGLVEAS FT GALRTIAVSLTKIANDIRLMGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVA FT AQVIGNDAAVAWGGANGAFELNVYIPMMARNILESYQLLTNVSRLFAERCIKGLSANIE FT HLRELAESSQSIVTPLNSAIGYEEAAAVVKQALKERKTLRQTVIDRGLIGDKLSLEELD FT RRLDVLAMAKVKPADS" FT misc_feature 334734..336038 FT /note="Pfam match to entry PF00206 lyase_1, Lyase, score FT 476.00, E-value 3e-139" FT misc_feature 335631..335660 FT /note="PS00163 Fumarate lyases signature" FT CDS complement(336240..336958) FT /pseudo FT /transl_table=11 FT /gene="ML1948" FT /product="probable transmembrane protein (pseudogene)" FT /note="Possible pseudogene of M. tuberculosis paralog FT Rv3645 (Best blastx score 178)" FT CDS complement(337327..337686) FT /transl_table=11 FT /gene="ML1949" FT /product="hypothetical protein" FT /note="unknown." FT /db_xref="UniProtKB/TrEMBL:Q9CBH8" FT /protein_id="CAC30904.1" FT /translation="MFWVGVRGCGGILLPDPAGGAKASERRLAGCRFSAPSTAPRPTFA FT VIDSSAILIPLRGHTYLDFVQKNANAIAALLVLVVIGVAGRGALILVSTLGWFVAGEEP FT TLDQRDTVMKIPGRQ" FT CDS complement(337739..338614) FT /transl_table=11 FT /gene="ML1950" FT /product="carbohydrate degrading enzyme" FT /note="Similar to M. tuberculosis carbohydrate degrading FT enzyme Rv1096 TR:O53444 (EMBL:AL021897) (291 aa); Fasta FT score E(): 0, 81.3% identity in 289 aa overlap, and to FT others e.g. Streptomyces lividans acetylxylan esterase FT precursor TR:Q54413 (EMBL:M64552) (335 aa); Fasta score FT E(): 2.8e-18, 31.8% identity in 236 aa overlap. Contains FT Pfam match to entry PF01522 Polysac_deacet, Polysaccharide FT deacetylase." FT /note="Similar to and ML2649" FT /db_xref="GOA:Q9X791" FT /db_xref="InterPro:IPR002509" FT /db_xref="UniProtKB/TrEMBL:Q9X791" FT /protein_id="CAC30905.1" FT /translation="MLKRPDTQAWRYSRTVFGVVAAGAVLVIGALTGHVTRADDMSCAQ FT VKCIALTFDDGPGPYTDRLVQILKDNDAKATFFLIGNKVATNPAGAKRIVDAGMEIGSH FT TWEHPNMTMLSTEDIADQFSRANHAITVATGRTPTLWRPAGGLSNEAVRQVAGRYGQAE FT ILWDVIPFDWTNDSDTVATRCMLMMQIKPGSVVLFHDTYSSTVDLVYQFIPVLKANGYR FT LVTVTELLGPRAPGSSYGRRENGPPVNQLHDIPANLIPALPNTSSPKPMPNFPITDISG FT QNSGGSNDGA" FT misc_feature complement(338051..338482) FT /note="Pfam match to entry PF01522 Polysac_deacet, FT Polysaccharide deacetylase, score 216.00, E-value 5.6e-61" FT CDS complement(338669..339970) FT /transl_table=11 FT /gene="phoH2" FT /gene_synonym="ML1951" FT /product="PhoH-like protein" FT /note="Similar to M. tuberculosis PhoH-like protein phoH2 FT Rv1095 TR:O53443 (EMBL:AL021897) (433 aa); Fasta score E(): FT 0, 92.8% identity in 432 aa overlap, and to others e.g. FT Escherichia coli PhoH-like protein YBEZ SW:PHOL_ECOLI FT (P77349) (359 aa); Fasta score E(): 1.1e-16, 31.2% identity FT in 276 aa overlap. Contains PS00017 ATP/GTP-binding site FT motif A (P-loop)." FT /note="Similar to and ML0627" FT /db_xref="GOA:Q9X792" FT /db_xref="InterPro:IPR006596" FT /db_xref="UniProtKB/TrEMBL:Q9X792" FT /protein_id="CAC30906.1" FT /translation="MTDIRTYVIDTSVLLSDPWACSRFAEHEVVVPLVVISELEAKRHH FT HELGWFARQALRLFDDLRLDHGRLDQPIPVGMQGGTLHVELNHSDPTVLPAGFRTDSND FT SRILSCAANLAAEGRRVTLVSKDLPLRVKAAAVGLAADEYHAQDVVASGWSGMHEIETC FT AEDIDALFAEGKIDLGEARDLPCHTGIRLLGSNSHALGRVTAAKRVQLVRGDREVFGLR FT GRSAEQRVALDLLLDESVGIVSLGGKAGTGKSALALCAGLEAVLERRSHRKVVVFRPLY FT AVGGQELGYLPGSESEKMGPWAQAVFDTLEGLASPAVLEEVLSRSMLEVLPLTHIRGRS FT LHDSFVIVDEAQSLERNVLLTVLSRLGTGSRVVLTHDIAQRDNLRVGRHDGVAGVIEKL FT KGHPLFAHVTLQRSERSPVAALVTEMFEEIAGPH" FT misc_feature complement(339209..339232) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(340320..341147) FT /transl_table=11 FT /gene="desA2" FT /gene_synonym="ML1952" FT /product="acyl-[ACP] desaturase" FT /note="Similar to M. tuberculosis acyl-[ACP] desaturase FT desA2 TR:O53442 (EMBL:AL021897) (275 aa); Fasta score E(): FT 0, 78.1% identity in 274 aa overlap, and to others e.g. FT Gossypium hirsutum (Upland cotton) acyl-[acyl-carrier FT protein] desaturase precursor SW:STAD_GOSHI (X95988) (397 FT aa); Fasta score E(): 5.6e-05, 23.9% identity in 293 aa FT overlap." FT /note="Similar to and ML2185" FT /db_xref="GOA:Q9X793" FT /db_xref="InterPro:IPR012348" FT /db_xref="UniProtKB/TrEMBL:Q9X793" FT /protein_id="CAC30907.1" FT /translation="MAQKPVPNALILQLEPVVKDNMARHFANEELWFAHDYVPFDRGEN FT FAFLGGRDWDPSQATLAKAVTDACEILLILKDNLAGYHRELVEHFILEGWWGRWLGRWT FT AEEHLHAIALREYLVVTREVDPVANEQVRVEHVMKGYRVNSYTQIETLVYMAFLERSYA FT FFCGSLAAQIKEPALFGLINQIVKDEVRHEEFFANLVAHCLECNRDETVAAIAARAAGL FT DVLGADIDAYHDKVENISAAGIFGSVELRQVISDRITAWGLINEPQLAQFVTS" FT CDS complement(341204..342484) FT /transl_table=11 FT /gene="glyA" FT /gene_synonym="ML1953" FT /product="serine hydroxymethyltransferase" FT /note="Similar to M. tuberculosis serine FT hydroxymethyltransferase glyA Rv1093 SW:GLA1_MYCTU (O53441) FT (426 aa); Fasta score E(): 0, 89.9% identity in 426 aa FT overlap, and to many others e.g. Escherichia coli serine FT hydroxymethyltransferase SW:GLYA_ECOLI (P00477) (417 aa); FT Fasta score E(): 0, 53.5% identity in 415 aa overlap. FT Contains Pfam match to entry PF00464 SHMT, Serine FT hydroxymethyltransferase." FT /db_xref="GOA:Q9X794" FT /db_xref="HSSP:1DFO" FT /db_xref="InterPro:IPR019798" FT /db_xref="UniProtKB/Swiss-Prot:Q9X794" FT /protein_id="CAC30908.1" FT /translation="MVAPLAEVDPDIAELLGKELGRQRDTLEMIASENFVPRSVLQAQG FT SVLTNKYAEGLPGRRYYDGCEHVDVVENIARDRAKALFGADFANVQPHSGAQANAAVLH FT ALMSPGERLLGLDLANGGHLTHGMRLNFSGKLYETGFYGVDATTHLIDMDAVRAKALEF FT RPKVLIAGWSAYPRILDFAAFRSIADEVGAKLWVDMAHFAGLVAVGLHPSPVPHADVVS FT TTVHKTLGGGRSGLILGKQEFATAINSAVFPGQQGGPLMHVIAGKAVALKIATTPEFTD FT RQQRTLAGARILADRLTAADVTKAGVSVVSGGTDVHLVLVDLRNSPFDGQAAEDLLHEV FT GITVNRNVVPNDPRPPMVTSGLRIGTPALATRGFGEAEFTEVADIIATVLTTGGSVDVA FT ALRQQVTRLARDFPLYGGLEDWSLAGR" FT misc_feature complement(341327..342472) FT /note="Pfam match to entry PF00464 SHMT, Serine FT hydroxymethyltransferase, score 753.60, E-value 5.4e-226" FT CDS 342613..343551 FT /transl_table=11 FT /gene="coaA" FT /gene_synonym="ML1954" FT /product="pantothenate kinase" FT /note="Similar to M. tuberculosis pantothenate kinase coaA FT Rv1092c SW:COAA_MYCTU (O53440) (312 aa); Fasta score E(): FT 0, 93.6% identity in 312 aa overlap, and to many others FT e.g. Escherichia coli pantothenate kinase SW:COAA_ECOLI FT (P15044) (316 aa); Fasta score E(): 0, 53.1% identity in FT 311 aa overlap. Contains PS00017 ATP/GTP-binding site motif FT A (P-loop)." FT /db_xref="GOA:Q9X795" FT /db_xref="HSSP:1ESM" FT /db_xref="InterPro:IPR004566" FT /db_xref="UniProtKB/Swiss-Prot:Q9X795" FT /protein_id="CAC30909.1" FT /translation="MPRLSEPSPYVEFDRKQWRALRMSTPLALTEEELIGLRGLGEQID FT LLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPGRPVPFIIGVAGSVAVGKS FT TTARVLQALLARWDHHTRVDLVTTDGFLYPNAELGRRNLMHRKGFPESYNRRALMRFVT FT SVKSGADYACAPVYSHLRYDTIPGAKHVVRHPDILILEGLNVLQTGPTLMVSDLFDFSL FT YVDARIQDIEQWYVSRFLAMRGTAFADPESHFHHYSALTDSKAIIAAREIWRSINRPNL FT VENILPTRPRATLVLRKDADHSINRLRLRKL" FT misc_feature 342901..342924 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT repeat_region complement(343568..344386) FT /note="Dispersed repeat, RLEP, copy 33" FT CDS complement(344379..345128) FT /transl_table=11 FT /gene="truA" FT /gene_synonym="ML1955" FT /product="probable pseudouridylate synthase" FT /note="Similar to M. tuberculosis probable pseudouridylate FT synthase truA Rv3455c SW:TRUA_MYCTU (Z95390) (256 aa); FT Fasta score E(): 0, 77.2% identity in 246 aa overlap, and FT to many others e.g Pseudomonas aeruginosa tRNA FT pseudouridine synthase A SW:TRUA_PSEAE (O87016) (285 aa); FT Fasta score E(): 4.2e-16, 34.3% identity in 242 aa overlap. FT Contains Pfam match to entry PF01416 PseudoU_synth_1, tRNA FT pseudouridine synthase." FT /db_xref="GOA:Q9X796" FT /db_xref="HSSP:1DJ0" FT /db_xref="InterPro:IPR020094" FT /db_xref="UniProtKB/Swiss-Prot:Q9X796" FT /protein_id="CAC30910.1" FT /translation="MLDEAFTTVFRTPVRLRAAGRTDTGVHATGQVAHVDIPGTALSKA FT NPRSPHTGDPEFLPLLRRLSRLLPVDVRVLDIACAPVGFDARFSALRRHYRYRLSTAPY FT GVQPNQARYVTAWPRELDLDSMSAASRDLLGLRDFAVFCRHRHGATTIRELQRLEWSRE FT GYLITAHITADAFCWSMVRSLIGALLAVGDHRRTIGWCGELLTKASRSSDFTTAPAHGL FT TFIRVDYPPDDELAERAVITRDLRSSF" FT misc_feature complement(344502..345140) FT /note="Pfam match to entry PF01416 PseudoU_synth_1, tRNA FT pseudouridine synthase, score 297.50, E-value 1.6e-85" FT CDS complement(345220..345732) FT /transl_table=11 FT /gene="rplQ" FT /gene_synonym="ML1956" FT /product="50S ribosomal protein L17" FT /note="Similar to M. tuberculosis 50S ribosomal protein L17 FT rplQ Rv3456c SW:RL17_MYCTU (O06323) (180 aa); Fasta score FT E(): 0, 81.9% identity in 171 aa overlap. Contains Pfam FT match to entry PF01196 Ribosomal_L17, Ribosomal protein FT L17." FT /db_xref="GOA:Q9X797" FT /db_xref="HSSP:1GD8" FT /db_xref="InterPro:IPR000456" FT /db_xref="UniProtKB/Swiss-Prot:Q9X797" FT /protein_id="CAC30911.1" FT /translation="MPKPTKGPRLGGSSSHQKALLTNLAASLFEHGRIKTTEPKARALR FT PYAEKLITHAKKGTLHNRREVLKKLPDKDVVHALFAEIGPFFSDRDGGYTRIIKVEARK FT GDNAPMAVIELVREKTVTSEADRARRVAAASAKAAQAQEKPAQEEEVEATSDEVAYTSE FT PDKAAEH" FT misc_feature complement(345385..345675) FT /note="Pfam match to entry PF01196 Ribosomal_L17, Ribosomal FT protein L17, score 176.90, E-value 3.3e-49" FT CDS complement(345756..346799) FT /transl_table=11 FT /gene="rpoA" FT /gene_synonym="ML1957" FT /product="[alpha] subunit of RNA polymerase" FT /note="Similar to M. tuberculosis [alpha] subunit of RNA FT polymerase rpoA Rv3457c SW:RPOA_MYCTU (O06324) (347 aa); FT Fasta score E(): 0, 95.7% identity in 347 aa overlap. FT Contains Pfam match to entry PF01000 RNA_pol_A_bac, FT Bacterial RNA polymerase, alpha chain. Contains PS00017 FT ATP/GTP-binding site motif A (P-loop)." FT /db_xref="GOA:Q9X798" FT /db_xref="HSSP:1LB2" FT /db_xref="InterPro:IPR011773" FT /db_xref="UniProtKB/Swiss-Prot:Q9X798" FT /protein_id="CAC30912.1" FT /translation="MLISQRPTLSEDILTDNRSQFVIEPLEPGFGYTLGNSLRRTLLSS FT IPGAAVTSIRIDGVLHEFTTVPGVKEDVTEIILNLKGLVVSSEEDEPVTMYLRKQGPGE FT VTAGDIVPPAGVTLHNPGMRIATLNDKGKIEAELVVERGRGYVPAVQNRALGAEIGRIP FT VDSIYSPVLKVTYKVDATRVEQRTDFDKLILDVETKSSITPRDALASAGKTLVELFGLA FT RELNVEAEGIEIGPSPAEADHIASFALPIDDLDLTVRSYNCLKREGVHTVGELVSRTES FT DLLDIRNFGQKSIDEVKVKLHQLGLSLKDSPDSFDPSEVAGYDVTTGTWSTDGAYDSQD FT YAETEQL" FT misc_feature complement(345894..346796) FT /note="Pfam match to entry PF01000 RNA_pol_A_bac, Bacterial FT RNA polymerase, alpha chain, score 584.60, E-value FT 6.1e-172" FT misc_feature complement(346158..346181) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(346884..347489) FT /transl_table=11 FT /gene="rpsD" FT /gene_synonym="ML1958" FT /product="30S ribosomal protein S4" FT /note="Similar to M. tuberculosis 30S ribosomal protein S4 FT rpsD Rv3458c SW:RS4_MYCTU (O06325) (201 aa); Fasta score FT E(): 0, 93.5% identity in 201 aa overlap. Contains Pfam FT match to entry PF00163 Ribosomal_S4, Ribosomal protein FT S4/S9 N-terminal domain. Contains Pfam match to entry FT PF01479 S4, S4 domain. Contains PS00632 Ribosomal protein FT S4 signature. Contains PS00017 ATP/GTP-binding site motif A FT (P-loop)." FT /db_xref="GOA:Q9X799" FT /db_xref="HSSP:1C05" FT /db_xref="InterPro:IPR002942" FT /db_xref="UniProtKB/Swiss-Prot:Q9X799" FT /protein_id="CAC30913.1" FT /translation="MARYTGPITRKSRRLRIDLVGGDQAFEKRPYPPGQHGRARIKESE FT YLLQLQEKQKARFTYGVMEKQFRRYYEEAVRQPGKTGEELLKILESRLDNVIYRAGLAR FT TRRMARQLVSHGHFSVNGVHVNVPSYRVSQYDIIDIRDKSLDTVPFQIARETVGDRPIP FT SWLQVVGEHQRILIHQLPERVQIEVPLIEQLIVEYYSK" FT misc_feature complement(347076..347219) FT /note="Pfam match to entry PF01479 S4, S4 domain, score FT 82.80, E-value 7e-21" FT misc_feature complement(347151..347225) FT /note="PS00632 Ribosomal protein S4 signature" FT misc_feature complement(347220..347489) FT /note="Pfam match to entry PF00163 Ribosomal_S4, Ribosomal FT protein S4/S9 N-terminal domain, score 95.90, E-value FT 7.9e-25" FT misc_feature complement(347247..347270) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(347523..347939) FT /transl_table=11 FT /gene="rpsK" FT /gene_synonym="ML1959" FT /product="30S ribosomal protein S11" FT /note="Similar to M. tuberculosis 30S ribosomal protein S11 FT rpsK Rv3459c SW:RS11_MYCTU (O06326) (139 aa); Fasta score FT E(): 0, 89.9% identity in 139 aa overlap. Contains Pfam FT match to entry PF00411 Ribosomal_S11, Ribosomal protein FT S11. Contains PS00054 Ribosomal protein S11 signature." FT /db_xref="GOA:Q9X7A0" FT /db_xref="InterPro:IPR018102" FT /db_xref="UniProtKB/Swiss-Prot:Q9X7A0" FT /protein_id="CAC30914.1" FT /translation="MPPKKANAAGPKKGQKTRKREKKNIPYGAAHIKSTFNNTIVTITD FT QQGNVIAWASSGHVGFKGSRKSTPFAAQLAAENAARKAQEHGVRKVDVFVMGPGSGRET FT AIRSLQAAGLEVGAISDVTPQPHNGCRPPKRRRV" FT misc_feature complement(347529..347858) FT /note="Pfam match to entry PF00411 Ribosomal_S11, Ribosomal FT protein S11, score 245.20, E-value 2.1e-75" FT misc_feature complement(347556..347624) FT /note="PS00054 Ribosomal protein S11 signature" FT CDS complement(347943..348317) FT /transl_table=11 FT /gene="rpsM" FT /gene_synonym="ML1960" FT /product="30S ribosomal protein S13" FT /note="Similar to M. tuberculosis 30S ribosomal protein S13 FT rpsM Rv3460c SW:RS13_MYCTU (O06327) (124 aa); Fasta score FT E(): 0, 92.7% identity in 124 aa overlap. Contains Pfam FT match to entry PF00416 Ribosomal_S13, Ribosomal protein FT S13/S18. Contains PS00646 Ribosomal protein S13 signature." FT /db_xref="GOA:Q9X7A1" FT /db_xref="InterPro:IPR018269" FT /db_xref="UniProtKB/Swiss-Prot:Q9X7A1" FT /protein_id="CAC30915.1" FT /translation="MARLVGVDLPRDKRMEVALTYIYGIGRTRANEILEATGIERDLRT FT RDLTDDQLTHLRDYIEANLKVEGDLRREVQADIRRKMEIGCYQGLRHRRGLPVRGQRTK FT TNARTRKGPKRTIAGKKKAR" FT misc_feature complement(347991..348311) FT /note="Pfam match to entry PF00416 Ribosomal_S13, Ribosomal FT protein S13/S18, score 210.40, E-value 2.8e-59" FT misc_feature complement(348015..348056) FT /note="PS00646 Ribosomal protein S13 signature" FT CDS complement(348494..348607) FT /transl_table=11 FT /gene="rpmJ" FT /gene_synonym="ML1961" FT /product="50S ribosomal protein L36" FT /note="Similar to M. tuberculosis 50S ribosomal protein L36 FT rpmJ Rv3461c SW:RL36_MYCTU (P45810) (37 aa); Fasta score FT E(): 1e-15, 86.5% identity in 37 aa overlap. Contains FT PS00828 Ribosomal protein L36 signature." FT /db_xref="GOA:Q9X7A2" FT /db_xref="HSSP:1DFE" FT /db_xref="InterPro:IPR000473" FT /db_xref="UniProtKB/Swiss-Prot:Q9X7A2" FT /protein_id="CAC30916.1" FT /translation="MKVNPSVKPMCDKCRVIRRHRRVMVICVDPRHKQRQG" FT misc_feature complement(348500..348577) FT /note="PS00828 Ribosomal protein L36 signature" FT CDS complement(348647..348868) FT /transl_table=11 FT /gene="infA" FT /gene_synonym="ML1962" FT /product="initiation factor IF-1" FT /note="Similar to M. tuberculosis initiation factor IF-1 FT infA Rv3462c SW:IF1_MYCTU (P45957) (72 aa); Fasta score FT E(): 9.6e-30, 100.0% identity in 72 aa overlap. Contains FT Pfam match to entry PF00575 S1, S1 RNA binding domain." FT /db_xref="GOA:P0A5H7" FT /db_xref="HSSP:1AH9" FT /db_xref="InterPro:IPR004368" FT /db_xref="UniProtKB/Swiss-Prot:P0A5H7" FT /protein_id="CAC30917.1" FT /translation="MAKKDGAIEVEGRVVEPLPNAMFRIELENGHKVLAHISGKMRQHY FT IRILPEDRVVVELSPYDLSRGRIVYRYK" FT misc_feature complement(348650..348862) FT /note="Pfam match to entry PF00575 S1, S1 RNA binding FT domain, score 43.00, E-value 3e-10" XX SQ Sequence 348950 BP; 77717 A; 107533 C; 94487 G; 69213 T; 0 other; gacgaaagta atgcggtagt ttccccagcc ctgaacggcg acatggtatg taccgagtcg 60 catgacgtct atcggactgc accgttgaaa ccacccgatg tcaagctgtc gtgtttgtgt 120 ctgtggcggt gagttgttcg gttggtttca taggtggtgg gtgaaatggc tgtttttgcg 180 ttttatgact ggccgatatg ttcggtagtc gtggggggca gcccggaatc ctgttgacgt 240 gttttgctgt gttgcggggt ttttgttggt gagtggctga ctgcctgctt tcgatgaggc 300 ttcgtgtgct ttgccgcagt ggacacgatt agcgcggcgc acgtaagcat gtcggtggtg 360 gatgctgctt ggtctacatg ttgatgatgc caggggctgg gcacctgggc tgtgctgaag 420 gcgatatcga tgcaggcgtg agtgtgagga tagttgttag cgccgcgggg taggggcgtt 480 ttagtgtgca tgtcatggcc ttgaggtgtc ggcgtggtca atgtggccgc acctgaacag 540 gcacgtcccc gtgcacggta taactattcg cacctgatgt tatcccttgc accatttctg 600 ccgctggtat cggtgtcggc ggcttgttga ccggccctca gccagcaagc aggcatgccg 660 ccgggtgcag cagtatcgtg ttagtgaaca gtgcatcgat gatccggccg tcggcggcac 720 atacggcaac cttctagcgc agatcaacca cccacacccc accagcccac cacaacacca 780 ccacccaagg cctcgcgggt gagtgcgatc gttaagcaac ttaccgagcg taaacacgcc 840 gtagagatcc tcggagccga agaataactg cacatctcgc gcgctgtatt ccgtttagcg 900 gcgctctcca gtgcgttcga cccccaggtc ggtcatggct tctttctacc aggtggtcct 960 cgcaccgaga tcgacggcag catggaaaag ttcgatagag caccacaccg acgtcaatct 1020 cgacgtgtgc acggccgaag ctaccgccgg ggccgaggtt ggcatctagg gcaatagaag 1080 gacgagcggt tcatgaactt ttcccggtgc atcaccgcgc cgcaacgccg gcagccttcg 1140 ccttcacgac cataggcatc caaagatcgg tcaaagtacc ccgattcgcc gttgacgttg 1200 acatacagcg aatcgaacga agtcccaccc ttggccaacg agtcgcgcat cacatcggcg 1260 gcagcatcca gaaccgcggc cagctgccga cgggtcagag tggcagcaat tcgcgcgccg 1320 tgcacttcgg cccgccacaa cgcctcatcg gcgtaaatgt tgccgattcc agatactgtc 1380 tgttgatcga ggagctggcg cttgagctcg gaatgcttgc accgcaacac tttcactaca 1440 gcttcgacat cgaaccgcgg atcgaacggg tcacgcgcca agtgggcgac aggcaccggc 1500 agcacactgc cgtccaccgt cattagatcg gctagcagcc atccccctaa ggtccgctga 1560 tccgtgaagt tcaacacggt cccgtcgtcg aacagcgcag agatcctaac gtgatcgacg 1620 cgaggcacgg tccccagcaa catctgcccg ctcatgccga ggtgcaccac gagcgcaatg 1680 tctgtgtcca gcaagaacca cagatatttg ccgcgccgat caattccgtt aatacgggtg 1740 ccgagcagcc ggttcgtgag gtcagttggt ccagcaacgt ggcggcgcac agcgcgcgga 1800 tggtgcaccc gaaccgcagt aatcgtcttg cctacgatat agtcctgcag gccgcgccgc 1860 accacctcta cttcgggcag ttcaggcatt tagttatgat cccaagcccg gcgaaaccgg 1920 gcgcagcgaa tcataaccat cgactacacg gacgttttcc cgacgccgcc cagcacatcg 1980 agtgctttcc aagccgctga tgcggctttc tgctcagcct ctttcttcga gtggccaata 2040 cctgacccgt attcggtgtc catcacgacg acaaccgcgg tgaattcttt gtcgtggtcc 2100 ggaccggtgg aggtcaccac gtacgatggc acgcccatgc cgcgtgccgc tgttagctcc 2160 tgcaagctgg tcttccaatc caacccagct cccagcgtag gcgcagcgtc cagcagcgta 2220 ccaaacaacc gcaagatcac ctgacgggcc acctcaatac cgtgatgcag gtagatcgca 2280 cccagcagcg attccatgcc gtcggccagt atgctggact tatccgctcc tccggtgttt 2340 gtctcgccac ggcccagcag caggtagaca ccgagaccac catcggataa gtttcgcgca 2400 acgtaagcca gtgcctgggt gttgaccaca ctggcacgca atttagccag atccccttcc 2460 gaacggtcgg ggtggcgatg gaacaactca tcggtaatgg tcaagctcag gacagcgtca 2520 ccaagaaact ccaggcgctc gttggttggt aacccgccgt gctcgtaggc ataactgcgg 2580 tgtgtcaacg ccagcgaaag tagctcatca ggcagatcga cgccgaacgc atcgagcaaa 2640 gcttgtcgag gctgggtcac cactcactcc gtgatccatc cgtttccgat gtctgcggga 2700 cgtcaggcgc caacatgtca gtcaacttgg cccaccacgg gtcgatgcgg tcatggggat 2760 gaccgggctc gacgaccagt gaagtaccac attctgcgca taatccaggg caatccgacc 2820 ggcacatcgg cgcgaagggg agctcgatcc ctacggcatc gatgatggac tgttcaagat 2880 cgatcgtgcc atcgaccacg tgtcctaccg catcctcttc ggtggtcacc ttcgtcgcac 2940 tgtagggata ggcaaacagt tggttcaagg tgacttgcac gtgtccatgg accgcggtca 3000 aacaacggac acattcgctc accgtaggag cagtcaccgt cccagcgacc aacacgtcct 3060 ctgacaccga ctccacacgc aagtcgagat ttatcggcgc accccactcg atcacgacca 3120 gctccaatcc aatgcgcgcc aagctgggca cggttttttg cagggcgatg atcgctcccg 3180 gtcgtcgtcc caacggggtg atgtcgaaca ctaccggtga gatcagatga cgttgcgtcg 3240 tgacaccata ctgccgcgtc atagtagaaa tcctacggca cccatcgcgt agcgccagag 3300 caacagtcac ctttcctcgt ggcgatggta cttaagcaga aagctagcgt gtcacgtaat 3360 cgtgcgtacc ggccgccgtg cggagctggt ggcggccgcg gccaaccgaa cgaagcgtac 3420 cgttgagaaa ctcttcgaac tcggcgagct tgttgtcgac atagatatcg cactcgccgc 3480 gcagccggtc cgcctcggcg tgcgccgtgt cgatcagccg ggtggattcg gcgttggccg 3540 cctgtaccac ctcgttttgc gacaccaagc gctgctgttc cttgatgccc tcttggatag 3600 ccttttcgta ggagatgttg ccgttttcga tcaaccggtc gcattcggat tgggcacggt 3660 tgaggctggc ctcgtactct cgcttcgcta ctgtagcgat gcgaatcgac tcctcacgcg 3720 catccccgag catccgctca ctgtgttgac gcgcctcgct tgccatccga tcaacctgcg 3780 atttcgcgtc agacaggatc cgatcagcct ccgcgcgcgc gtgactcaac aatgactccg 3840 actcagtggt cgctgaggac accatggaat cggcatgcgc tttggcgtcg ttgagcatcg 3900 catcacgcgc gtcgagcaca tcctgggcat catccaactc acccgggatc gcatctttga 3960 tatcgtcgat cagctccagc acatcgccgc gaggtaccac acagccagcg gtcatcggca 4020 cgccccgggc ttcttcgaca atggcaccca attcgtccag cgcctcaaag actcggtaca 4080 cagccatacc ctcctggcct cgttggttgt taccagtgtg cctgctgtta ccgctgtcac 4140 gatgttgctg gctcggtgtg tcggacatta tggcctgaac agccacctat gtggccgaca 4200 tggcggatca cattatactg gttcgcggtt gaaattatac ctgtagaggg tacatggtga 4260 cgctctggcg caggccgtcc accgaatacc atccgtggaa cggccgatga ccgctacgca 4320 ctctggccat cgcggccgag cgggaagtga catcgtcatc gtattcctac accgctgcgg 4380 cgttggctcg atcactgttc tgcaagggag ctaacttcta tcgccgccat gacatttgag 4440 atcagctacc accaatctca tggtgaagtg agtgattgtc ctggccctgc tgatgaattg 4500 gcaattcatc agagcagagc tcatcggcga gctaccgatg atcatgatat ctggccgttt 4560 tactccggct gttcgtgcgc tctcgactca tcgacaccgc ccgccatcag gccatggcat 4620 tgctgactcg atgaaagctg atgccgcgat ggacatgtcc atcgcggcat gagctccaaa 4680 ggcgataaca cactgcggtg acaactgttt ttgccccagg gttttacctc ggtctcccat 4740 gatgttcatc atgggagcgg ctagccactg taggagacct cgttgtcaaa tctgttgctc 4800 gctggtgtta tcgccgccta gataccccaa atcattttga caaaaattct ttttcgccta 4860 ttacccagtc agggtagcac tgtgggggcc gatcgtggca atcagccgtt cccggcttaa 4920 tgccgcatat ccagcacagt gctgggctag gagcgccgtc gaccgaccgg ttcggaatag 4980 aacagaacca ccgtagtaaa ccaccgtagt aatagtagtc cgaggtcgga aaaggcgact 5040 aatgatcaag gagcagcgaa ttcgcaaagg cattaggagg ttatcatgcc ggatgatgcg 5100 ccgctgaatg gtggtgctct gtgcaagcag gacctgatgg accctagcgg taaggatcgg 5160 aaatacaggt caaacgtcac cgatgggcga cagccgatcc cggccaccgg ttcgatgatc 5220 tgttcaattc cgtctccgac ccagtcacct tggtggtggc attgatcggg tagcaaccaa 5280 cccgagtgcc cgtacaacag caagatcgaa cgggctgact gtggacaccc gcatcaactc 5340 caaggtgaag taccgatgtt cctaggaggg ctacgcatac cgctcaaaag tgagcagttc 5400 caacctcaac cggtgcagga tacacaagat ccccaaatca agcaggtcgg gcaagttgct 5460 gttgctggag attcccacgg tggccgacca tgtcgtcttc caggtgacgc taaaactgtt 5520 gctagaaacc atcttcgaga ccgacttcaa gccattttcc tgcgggtttc ggcccgccca 5580 gcgcacacac gacgccatcg ccgagatcca tctgttggcc acccaggaat accgatgagt 5640 gttagacaca gatatttgag acgtactttg accacgtaga ccacccgacc ccaatagacc 5700 aggtgctcca gcggatcaaa gacaagcggg tgctgcggct ggtcaagtcg ttcctcaagg 5760 tcaggatcct cagtgaactc ggcgaactac gagaacaccc atatcagcac gccgcaagac 5820 agcctcttgg tcccgctgct ggccaacata gcgtcggcag tactcgataa gcacctacat 5880 atgccgcgga aaccgcggca accaaggttg accagtacgc cgacgccgtg gctggaaagg 5940 actgccgaac tggcgcctag ttggttacgc ggacgatttt gtagtgctgg tcaaaagatc 6000 ccaaagccac atcgaaacac tacgcaaaga catcacttgg gcgctcgaac taatgggatt 6060 gcacctatcc gagaccaaga cccaaacagt acacataagt gaggggttcg acttttttgg 6120 tgccacgttc agtggcacca aaaaacagca ataacccaaa cctagttttt tgaccgcggc 6180 cttaactagt gccggacatc ttttcccgga atcggcggtt caccgattcc ggcaatagct 6240 ctgaaacgtc gccgcctagc atagcaacct ctttgaccaa cgacgacgat acgaacgaat 6300 accgcggcgc cgttgcgacg aagaaagtgt cgacgcctgc gatgtgtttg ttcatctgcg 6360 ccatctgcag ctcgtattcg aaatccacgc cggtgcgcag gcccttcacg atggctgtca 6420 tcccacggga cctgactaag gcgaccacca atccctctcc ggcctccaca cgcaagttag 6480 gcaggtgcat cgtcgactca ttgatcatcg ctatccgctc gtcgaggtcg aacatgccct 6540 tcttgacggg gttgatcagg atcgcgacca ccacctcgtc gaactgagcc gcagcgcgtt 6600 caaaaacgtc gatgtggccc aacgtcaccg gatcgaatga ccccggacat accacactgc 6660 tcatgatcga aacgctacac ggcggatcag gtcagttcgg caagctccaa acgggtgtca 6720 ccgtacccac gcgactgcca cgaactccat ccggccggcc aggtcaacgg cacgctcgcg 6780 gcgccacgtt ctatcaccgc gacggttccc ggtcgcgccc agccgtaggt ggtcaacgtg 6840 gccagcaccg cttcgacctc agctgtgtcg atcgcatagg gcgggtcggc cagcacaaga 6900 tccatcggag acgcggtccc ggcggccagg acagtggcca ccgggccgca gcgcggcctg 6960 gcaccaacta gacctaaggc cgtcacgttg cgctcgatga cagcaacagt acgcttgtcg 7020 gattccacga acagcgtcga cgcggctccg cgcgacagag cctccagacc gagcgcacca 7080 gaaccggcgt aaaggtctaa taccgccaga ccggtcagtt cccgctgcgc agccacgatg 7140 ttaaaaagcg actcgcgcac ccgatcagtg gtcggcctgg ccccccactg cggaacaaca 7200 atgcgccttc cccgcgctac gccaccaatg atccgggtca gctcagcacc accagcaaat 7260 ctccgccctc catcgcagcg gtaccagaca cttccacccg caccacgaca gcatcctccg 7320 gggcagtgat cagagcttcc atctttcatt cgcctcgatg ctggcgatgg tctggtcaat 7380 gttgatttta gcaccaacag acactgcaca cagtgccgac tccggcgaag ggtgtcgcaa 7440 tgtatctggg attaccgtga tcggccttat cggcggccgg aaccgagttg gtgatgcggc 7500 ggtcacgcac cagaattggc ttcagctggt cattgatgat acacatcacc atttgcataa 7560 cacgctcgtc aggatcagag atggcctcca gcccgatcat cagctcaaac ccacgttcca 7620 gttccaccct gttgctcttc atcctggcga aggccgcaaa agaactggtt gaccgacaat 7680 cgcgaagtgt caccgtaggt ttttcgatgc tcctcgaatt cctttgccag aatcgggaat 7740 aacaacctac taacgtggct tgacgcttaa gactggccag ggttcgggca cctcatcgtc 7800 gctggctaat tgccgaatgg acttggccgg agcgcagccg gccagcaccg tcgtgaacag 7860 cggttccgac cagccgccgt acggatcacc aagctcgccg tgcagtaacc ccatcaccaa 7920 atctgggatg tcgaatatcg cactggatcc gagtcaaatt cgtctgcact tacctcagcg 7980 ccaaccaaca ccagcgccag ataaccagcc atcgtaaacg tcggcatgac cttaaccaat 8040 ctgttcaaca cacggtcggc ccccgcatag gtcttctcga atcgattcac cagacccagc 8100 gcaatcgcat gctgacgcag attcgataac tggctactca gaatctcatg gtgatacgac 8160 cgtcctgtcg gacagggtag accagattcg aagagtgcgt atacttttcg tagaacttcc 8220 cagtactgct ccaatgcgca cgcggcgaag agcgacagat cggtttcgta ctcgctgtga 8280 gctgcagcag ccacaatcga gctcaacgca ggctaggctg gttgttcctg ttagcgacaa 8340 ggcagcaccg tcgacggcgt cagcgtgcca agcggccata tagctgacca gctgcccacc 8400 cggtgtgtca tggatgtata cgtgcacgga cagaccgaaa caactgcgca acgcaacgac 8460 taaccactgt gcgcccggtg tccgcaacag tccggccgta tccttgatgg ctagcacgtg 8520 tgcgccagca cccacgattt gctcggcaag gttcaaacag tagtccaacg tgtagagtcg 8580 ctcccccagt tcggacaaat caccggtgta gaacattgcg acttttgcta ttgcagaaca 8640 cttttcatgt accgggtcga tctcctggtg catcgactca acattgttga gcgcatctaa 8700 aattcggaag atgtcaacaa cgatagctgt tgcatccgct acgaacaccg aggtaaccac 8760 ctccggatac ggtgtgtagc caaccgtgtt ccggccccac agcaacatat gcagacagat 8820 gttgagcagc acaacacgca gcgcagccag ccgctcccag agcgtctcct tgaggaaaca 8880 cgcagtgcca cttggtacgt cgcacctccc ccaacactcc atcgaccaca gctgtggcat 8940 tctccgggcg agatactttg ccaccctagc caacccgccg acactcactc gggtagccag 9000 cagcgattag tgggtgacgc taaacgtcgt atcggtaacc cctactgccg ccaattcccg 9060 caaccagcac gcaaaacgct gggacaccaa cccaaccaat cgctgcttag atccgtcggt 9120 ggtgaagctt gcagatcgat gtcgggcagc ttgtcgtgta ggtacaccgt tgacgatcgc 9180 aagccatccg gccggttgac ggtgtcggct agatagttgg ggatcttggt atcgcgatcg 9240 gccgaggcgc gcagggtcaa caactgtggc cactcgtcga tgaacaatgt ggtgagtcgg 9300 ccggcctgga aattcgggtc atccaagacc gcgtgtaaga agaaaatact cgtcgacata 9360 ccacgaatcc ggaactccgc aaccgcccag cacgccctgc ccaccgtcgt cggaaaatca 9420 cggccccagt aggtcagctt gaccagcatg aaatcgcagt ccgcgttgac cgcggcacca 9480 gggttagggc tgtcgtccaa ccggatgtcc accccaccgg gactacggta cacgctgatc 9540 caaccggtat cggacctaaa aacgttaacc ggatcctcga tggtgatccg gcgacaacac 9600 gacaccgtgc ggccgagtgt cttgctggcc taaatccagc tcgtctagca acgctctaac 9660 ggcaatccac agctggctga agaccagatc gacatcgacg atctcctcag ttacgctgca 9720 ctccacctga atccgcggat tcatctcgat gaacacacac tggccatcct cacccagtag 9780 agactcggcc aggctaacac tacgtgtacc cgatatgcca ggcaaaagcg accacgttgg 9840 cgaacatttg tcacgcaatt cacgcgggca agcccggtac ggacgccagc tcaatgacct 9900 gttgatgacg acgctgcaaa ctgcagtcgc gctggtacac tagatattaa gcgtggacaa 9960 cgttgccgag gttgtcggca aggatctgcg cttcgacgta gtatggttgc agtattacct 10020 gttcgtgcga gtataggccg tcgaatcctc gaacgcggat ttgggttctc ggctggcggt 10080 ttcgcgcagc acgctcacat cgttgacacg gcgcatacct cgaccgccgt cggcaaccac 10140 tttgacgaac aacggaaacc ggatgccgat ctagcccgac tcgagggccg acatcagcgc 10200 atcgatcaag actaaatggt gccgacaaat gaaaacaggc aggccaactt cgcggaccgc 10260 agcgaacaat cacccgggac gtatttcctt tcagcttaag cacttcggcg gtggggccga 10320 cgtacgtgat gcctactgcc gcgcacaccg cagccaactc taggttctcc gataaaactt 10380 agcaaaaata gacggagtca atgtaacgag ccgtgtcgac gatttgatcg atggacaggt 10440 aaagtccgca ccggatgacc aacgtcgccg atagataaag taagactcgt caccttaagt 10500 cgatactaca aattgcggtg ctcgtaagga tacaatgcca ccgtgcctac acccggttcg 10560 taatcaacac ggaaaacgcg gatcgggatc tccctgagat tagccgacca acactttagg 10620 aaaacacgcg tgcccctaaa agccagtaac tcataaaagt gtctgccaat agttccagaa 10680 ccgcaccatg atcagcagaa acaccgtaat gaaccacaga gtggcaatcg accatcgcca 10740 ttggtaaatt ccccgggcta tggcgctggt ccggccaggc aggacctcga gcagcggacg 10800 aaacacgatg gcggtgacca ccaccagtag cgacacgctg acagcccaga tcaccatgca 10860 gtaggcgcac aacgccccga tgcggtacag actctgaaag atcagccaat gcacaaaccc 10920 cacaccagcc aacgtaccaa ccgccaatcc aatccaatac cattgcggca gtgatacttc 10980 cgcgaccgac agcacaccgg tgacagtcac caacgtaaag cccacaatac ccagcaacgg 11040 attggggaaa cccaatacag acgcctgcgg tgtgctcatt accgagccgc acgcgacgat 11100 cggattgaca ttacacgacg gcacgtaagc cgagttgagc aaaatcctga tcttctcaac 11160 ggttaacatc atcgaggcga ccaagccaat cacacccgca atcagcaccc accatgcggt 11220 gggcaccggc atcggcaaca cgctagccgg agccggtttc aggtcgccgg gacgctcgac 11280 aggttgtgct gacaccgcgt aagttacgtt gtcgtagcag tgacagccac gtcgatgccc 11340 gggacggcgc ccacgattgc tttaatcttg gccaccagtg cttcgggtgt caacgggtcg 11400 tattcgtcgc cgttgatctt gatcgtcggg gttgccgaga tcttcgcgag cgctgcttct 11460 gcggtgacct tggccaggta cttcccgctg ttaatacagt ccgggacctt cccaaccacg 11520 ccggcttccc gcgcgatttc gatcaacttc gcattctcag ggaaactgct cgcaagttca 11580 ctgggttgga agctgcgact gtacaacgca gcacggaacc gacggtaagc atccatggat 11640 tcatcggcta cgcacaagga cgccgcacct gcccgtgacg gatagttatg gttacgtggg 11700 tggtcaagaa tggacaccac ggagtaatcg gccgcaatcg caccgatgtc gatgagcttg 11760 gacaccgtag gcccaaaatt ccgctcgaaa tcaccgcacc ccgggcacag gaagtcctcg 11820 taaaaagaca tcacgacctt ggggtcgtgg gtgccgggct gggtgactaa cttgctcgaa 11880 gtcacccgca ccgtgtcacc cgagccggtc agcggggccg cgccatcttg cttggcatgc 11940 tgcgatttca tgacggcgaa gacgacgaca accgcgaaga tcgcgacaat cacagtgccg 12000 gcgatcacga cagcccggcc agaccggccg tctaccgact ttaggtcgaa tcgctgaaga 12060 cgtttgcggt tatcggccac aggttcgctg atcctcacgt gctcgatttg gcccgatcac 12120 gatcgggcga cggcgtctct agagtaccgg cgacggtgaa ttgggtaact atacccggct 12180 caggtgagca cgcagtgccg aaatcagcac actcgtcgca gctgcacagc cgccgagcgg 12240 aaacaaattg gcgaagccgc gcgacagcga accgaaggaa cgcaggtaca ccgtagtctc 12300 gtcggcccgc agcaccggcg cgcagctctc acctcggtcg cacgcaatag ggcgaatccc 12360 actaccgcga tcagcgccgg cgccagcccg gccagcgact cggcctgcaa cggcgacaac 12420 cgcagatcag cgtgctcgat accgcagtcc ttcaagtatt gcgcttgaaa tgaaatccct 12480 atcccgcttg gtcaacaaaa aaccacgggc taacagcgtc attgaccggg taatgtgtgt 12540 gtgcgagcgg atgaagtcgg tccgcgggta aagcagccac tgcagcaccg gagcagggcc 12600 gtcggcagct cggaccaatt ggcacaccgt agacggcagg ttaccgccgg cgctgtcccc 12660 gcccaccgcg accgacccgg agctggcgcc gagttgctga tacgcctatt caaggcatcc 12720 tcgatcccgg ccagggccag atacccggat actcagtcgc cagtcggtag tcaatcgaca 12780 agacgtggat gtcaactcgc ggcacgtcaa ccggcacagc gcgtccgtag gtgtccagat 12840 cgccgagtgt acaaccaccg aggctagaaa cggggcagcc acgccactgt ccgggcgata 12900 gtaccgtgcc gagatctcac catccggcac aggcaacgaa atgtcgttta cttcgacgtg 12960 gagctgcgag cccggcaaac acaaaaggag gcctagcgca ttttagtgcg agatgcggca 13020 acgttgtcgt tgacgaccaa gccgtcggta aatatgctga acagcatcag ctgcagcatg 13080 ggggcaagtg tgtttccgtc gataatgacc acccgaccaa cagcaccctc ttaactacac 13140 tcggcatcca cggaagaacc ttggcgccaa ccgtggcgat cttcttgcct tgcatgcgac 13200 ttgtccaccg cattggttta cggtttagcg ccaagatgaa ggtctactgc gcctggcaga 13260 ctctaacagt tatggtcata tccccgaaaa agaccttgta actctgaaca acggcaattc 13320 gatccccgcc gtcgggctcg gcgtgtcccg gatcgcgccg gccgacaccg aatagacggt 13380 ctacatcgcg ctacgcaccg gttatcggca catcgacacc gcaacgatct accagaacga 13440 gcgagaagtc ggacgaacga tcgaccgaat tccggtgcac cccgtaacca actgtacgtg 13500 gtgacccagt tatggaatac cgaccacgac agcacactga cagcgttcga cgccagcatg 13560 gagcggcctg ggctcgacta cctcgacctg agccgttgac cgcagtcggt gctcaacaag 13620 ttcatcgcta ccttaaaaga ttgtaaggca tccgcccgcc tacctgacca gaacaggatc 13680 cggtccgtcg gagtcagcaa cttcgagccc gagtacctca gtattcctga tcaatgccac 13740 cggcattgct tcagtggttt atcagatcga gctgcatccg cggctgccac agcgagagtt 13800 gcgcaaaatt cacacccgcc gcaggatcgc caccgatgcg tggtcaccac taagcaaggg 13860 gtcgctgttg gtccaccaga cgatcaccgc cgtggccgaa aagcggccac agttgttgat 13920 tgggtggcac atgcaactcg gtaatatcgt gattcccaag caggtgaacc cctcacggat 13980 tgcgagcaac ttcgacgtgt ccgagttcaa actcagcgcc gcggaaatgg catcgatctc 14040 ctcgatcgat gaccgaaccc ggcttgaacg caacccatgc accttcgatt tcacaggcag 14100 gtgaaatgat gccgagcacc ccccgcacct ctataccctc aataaccctt aacgacgaga 14160 acactatgcc gttgctcggc cttggcgtcg cggaattgtc ggaggacgag accgagcgcg 14220 cggttttggc agcgctggaa atcggctgcc ggctcatcga taccgcagca gcttatggca 14280 acgaagccgc agtcagccgc gcaattgccg cctccggaat tccccgcgcc cagttgttcg 14340 tcaccaccaa gttggctacc cccgaccagg gtttcaccaa gtcccaagat gcctgcaacg 14400 ccagcttgga tcgacttggc atggactacg tcgacctcta cctgattcac tggccggccc 14460 cgccagtggg ccagtatgtt gatgcctggg gaggcatgat ccaatcccgt ggcgaaggcc 14520 atgcccgctc gatcggcgtg tgcaatttca ccgaggagca tttatcggcg attatcgatc 14580 tcacctttgt cacgccagcg gtcaaccaga tcgagctaca cccactgctc aaccaagacg 14640 agatgcgcaa atcaaatgca cagcacaacg ttatcaccca gtcctacacc ccattggttc 14700 ttggccggtt gatggacaat tcgaccctga ccgcgatcgc cgccgaatat ggcaaaacac 14760 ctgcacaagt actgcttcgg tggaacttgc agctgggtaa tgcagtagtc ttccggtccg 14820 ccaaagccga gcacattgcc agcaacttcg acgtcttcga tttcgaattg gccgtcaatc 14880 acatggacgc aatgaatgag ttgcacgacg gcacccggtt gcgcccagat ccagaaacct 14940 acgccggcag ctgatctcgc cccgtaactg ctacccgacc tgacaaggtc actacaactt 15000 acaggtagta cgctcatcga caccctcgtc taccggtagt tggtaaccag catagcaccg 15060 cgacgaactg catggcgtat ttggcacgta aacgcggcgt tcgacgacat ctaccaggcc 15120 ggtggcgaat cgctcttttt ctggattggc ctggccatca acagctagca agttggccag 15180 atcgttggca aaccgcaacc actgtcgatc aggccagctg taggctccca tgtccaacca 15240 taggcgagca ggacaatgtg gtcgatctgc actgattcgc tgacctttgc ggccgcgttg 15300 gaaggcgatg gcctgattgg tgtacggatc atgcagcgta ccggtagcca ccgcatttgg 15360 acaccgcttg atccacacga acgccttgtc gacgagatcg cgggtgagga tttcgtcgct 15420 ggtgtcacac ccattgtgcc caagagaggc atcgttgttg tcgtcccaca ggtgaccgaa 15480 cgccgaccga tggtaatcgc tgcgatgcag gcgccgcagc agcactaaca acattctcca 15540 gcacatcggt acccagctgc cacctcggca tgtcagtgct cgcggcaaat tcatcaacgt 15600 gcctgactga agatgctccc aacgtctgat aggcaactat taccgcgcac accacaacaa 15660 ccgacaacca cagcagcact ttagctattc accagctccg cgctccgcca caagcagatg 15720 gggggtactt cccacttgtg aagggtttca cccactgcat cgtcactgga cgtcatgact 15780 tgcctaagta ttctatacgg tcggtgtcaa tgaatcgtgc tgccaaatct gccaatcccg 15840 gatgcggggc taatccgagg tgcggatact cgtaggcacg cgtgcagaaa tcccttgcgg 15900 cctcaatgaa cacctgatgc tcggccaatg acagcatccg cagggtaatt gcctttccgg 15960 attggttgcg gcccagaaca tctccttccc gacgctcctt gaggtcgaga tcggcgagtg 16020 cgaacccgtc catggtctcg gcgacggcac atagcctgcg cccggccggg gagcccggtg 16080 agacccagct ggccaacaaa cacaggctcg gatgcgtgcc gcgaccgatg cggccacgca 16140 gctgatgcaa ctggcttatt ccaaaccgat cggcgtccat caccagcatg atggtggcgt 16200 taggtacatc tacgcctacc tcaatgacgt tggtacacac cagcacatcg atttcgcctg 16260 cacggaaagc catcatcgca gcgtccttct cgtcagcgga caaccgaccg tgcataagcg 16320 ccagccgcac gttagccagc tcaccagaac gcaatcgtgc gtagagaccg tccgcggttt 16380 ccgatggtct gctgttttgc ccccctttct gcggatcttc ggtctcgtca atccggggcg 16440 ccaccacata cgcttggcgg cccgcggcga cttcctcgag gatgcgctgc caagcccggt 16500 ccagccaccc tggcttgtcc ttgacgaaga tgacgttgct ggttatcggc tgacgtccgc 16560 gcggcagttc gcgcagtgtc gacatctcca agtcgccata gacggtaagt gcgacagtac 16620 gcgggattgg cgtcgccgtc atcaccaaca gatgtggcat gatgccagtg cgggccttgg 16680 tacgcaattg atctcgctgc tcgacaccga aacggtgttg ttcgtcgact actaccatgc 16740 ctaggttgtg gaattcaatc gcgtcctgca gcagcgcgtg cgtgccgatg acgatgccag 16800 tctggccgct gaaaatgtcg gcgcgaacct ttttcttctg ggccatcgtc atcgagccgg 16860 tcagcagagc cacctgggtg gcattttccg ccccgcccag ctgacacccc atccccaacg 16920 ggccgagaac gtcacggatc gacagtagat gttgtgcagc aagaacttcc gtaggagcca 16980 gcaacacgca ttggtagcca gcatcaatca tctgcaacat tgccaatacc gcgacgatgg 17040 tcttgcccga cccgacttca ccttgcagca ggcggttcaa cggacgggta gccgctagcc 17100 catcggacag cacgtcacgc acctcacgct gtccctccgt aagctcgaac ggcaaccgcc 17160 gcatcagttc tgccatcaga ccgtcagacc gcggcggcgc cgacggtccc gattccgaca 17220 gttcaccatg ccttcgggtt accaacgccc actgcaagcc gaccgcttcg tcgaaggtta 17280 gccgctcccg cgcacgccga cggtccgact cgctttcagc gagatggatg gcgcgcagtg 17340 cctcatcttc ggagaccagg ccatgcttgg cgcgcagatc cgcgggcaac ggatcggcca 17400 ccggatcgag gacctcaagc acctgacgca cgcaggcgta gatatcccag ctctgcagtt 17460 tggtgctggc cggatagatc ggaaagaatc gacgttcgaa cgccgacatc agcacttcgc 17520 cactgacagc ctgtgaagca tcggcgatgc ggcgcagcga gctactgccg cggttgcgtc 17580 cgtccggcga gtcgagaatg agaaacgcgg ggtgcgtcag ctgcataacg ccccgaaaaa 17640 atccaacctc cccagagagc atcacccggg tatctttggt tagcccctta ctgatatagc 17700 ccgcattaaa aaacgtagcg atcaccttgt tgcgtccaga gccgaccgtg agacgtagat 17760 acttcttttt cgagtccttc ttcatcggta acgtcaccgc ctctgtgatg acgtcgacga 17820 tggtgatgtg ttcacctgct tccggccgct cgtcttgggc gccccgcaca gtcgcaccct 17880 tagtgtaact gcgtgggtaa tggcgtagca ggtcgtcgac agtgcgaata ccaaacactt 17940 cgtcgaggga atcggcagcc ttggcgccca cgatgtagtc gagccgatcg gatagtgaca 18000 ccatagctac tcgactccga tcagcaacgc atcaccacga tgcccgcagc ggtaagtcac 18060 caactcagtc tccggatggt tgttgtgccc gtactgttgc aggatgtcgt tcaacgtggc 18120 ggcgttaact gctgtgtcga tacctgcccc tagcaacaca gttaccagtt caccacctga 18180 ggccagcaaa agatcaagca gaccgatcgc tgctctcacc gcatcagcag ccacgaccaa 18240 taccacgtcg ccgacgatgc ccagacgata accaggtcga cagtaacctg cccaggccaa 18300 cgcgctctcg gtcgtgacgc gtgccgatcc gtgccgagca gcaccggagg cacgggccat 18360 ggtgtagccg tcgttgactg cttgacgacc cgtatcatgg acaaccagca cggccaggcc 18420 ttgcaccatc gacccggtcg gtatcgacac cacgtcgatg ccccagccaa tagccgccgc 18480 agtgcgacct gcgacgagct cctcggcgat ctaaatagct gttgagcatc agcatcacct 18540 gagcggcgcc ggtatccact acagcccgca tcagctggtg ggcactgata tccatggccg 18600 gatcgacagc atcgggccac gggtgcagca cgcagacccc tgcaccggcg aacaactcgg 18660 cagcacagtc gccatcaaca acaaccggcc agcaccgccc gttcccgcgt ccagctgccc 18720 accgataatc cggcggcgcc agagtcggag tccaacggcg agaccacgat ccggctgagt 18780 cgtcctgcta ccaatcctac ttcgatagcg gcgccggcat cgtcagtgtg tacgtgcacc 18840 gagtaactgc cgtgcgtcgc cacaatggct accgattccc ccgagccgat cccgaagcgt 18900 atccacctcg tacacataac actcatccgg caggtacatt acctagaatt gcggtgcccg 18960 gcgtccggtg acatcatctt tttcatcgga cgacaccgcg cacggcgaaa gctcgtacac 19020 tgtgcacgcc ggcaccccgg tgaggggcaa gcgcagtgtg ttcaatagga ccagcagacc 19080 ccgtccgcca gcatccaccg caccggcatc agcaagcaca tcaagctgct cgaaagtctt 19140 ctctagcgcg acaacggtcg cgtcaccgac ggtgattatc gccaacacca tacccttccc 19200 cgcggggggc gcactgctcg acggcatccg cggcagcccg caaaaccgaa actatggccc 19260 ttgagatctc cgcaccaccc gtggagttga tgaccagctc aacaccacat tgcaacccgg 19320 cccggaacag tctgacatcg atatcggaca gttcaccgcc gtactgggag accgcacttg 19380 cggttaagtc ggctatggca cacacaatct gggacaggag cacgccggag ttgccgtggg 19440 cgaccgttta gggcgccttc tgacagagct gccgtaaccc gagcaacgtg ggtcctaggc 19500 agccccctgc acgtcggctc tcgcactaac ctcagccagt gtggaacgcc tggcgaagaa 19560 catgttggcg gccaatatcg gagccagcga ccgggaacac attgagccgg ttgtctcgtc 19620 gatgtgggcg ataaaatcgc cgatgacaac gtgcgcccca tatcgtaatg ccgacgcgtc 19680 cagcaggcta tcctgtgaac tataaacagg cgctcagtgt gacccacctc cttcacacca 19740 catacccgcg ggggggcgaa ccgaatcatt gggactagta gctaacgagg atggaccata 19800 cagaccgtga ccgtcatcca gcagctgttg accgtttttg gtggttgccc acaacagtcg 19860 ctatcctgag ctggcgcttg ggtcagtcta ggctgccctg gctcccaaat atgtcagttg 19920 ccggattcca gcagaagagt tgaggagcat tcagaatggc cgctgtgtgc gatatctgcg 19980 ggaaaggtcc cggcttcggc aagtcggtat cacactccca ccgccgcacc agccgccggt 20040 gggatcccaa tgtgcaaact gtgcacatgg tgacgcgtcc cggcggcaac aagcaacagc 20100 tcaaagtctg cacctcctgc attaaggccg gcaaggttac ccgcggctga ctgttgcgcc 20160 agcgccccag cgccgaggtc ggcgcgcaca cagcgacgca acggtcaggt caatacggga 20220 cgacgatgaa cggtcttgtc cgcggccggc ccggtcaccg gcagcttccg acgaacgcgg 20280 caagtgtcgc aggctggcct cgatcttgtc cgagctgtca tgtcggtcag ggtaggcgcc 20340 aattgatggg cccagcaccc atcccgacga gtatctcgtt ggtacggctg aacgggcgcg 20400 agccgaagaa cccgcgagat gccgacagcg gcgaagggtg cggcgactcg atcaccacac 20460 agttatcgac agtcagcagc ggcttcagcg tggcagcatc gcgaccccac aaaatcgcca 20520 ccatcggttc tgaccgcgca gccagcgcgc ggatcgcaca ctccgtgatc acttcccagc 20580 ccttgccccg atgagacgcc gggttactag ggcgcaccgt gagcaccctg tttaacagca 20640 gcacaccacg ctgcgcccaa ggtgtcagat cgccacacac aggcaaagga tagcctaggt 20700 ccgcagtgta ctcgtcgaag acgttggcaa gactgcgggg cagcggacgc acatcggggg 20760 ccaccgaaaa actcaggccc acagcatgtc ccggtgtcgg atacggatct tgcccaacga 20820 tcaaaacgcg cacgttgtcg aacggataag taaaggcgcg caaaacacta tgcccggcag 20880 gtagatacct gcgcccggca gcgatctcgg cccgcagaaa tcgacccatc tcagctacct 20940 ggtcgacgac cggctctagc gcggccgccc acccttgctc gacaagttca ctcaacggac 21000 gtgcggtcat cccagcccct gcgcacacag caccagcagg tccttcacga ttttccggta 21060 ttcaggtgat tgccggtcgg tgaacttcag cgcggcaata gcgtagacgg tcaccgcgac 21120 accctaacct ccaaaggatt gccaacccgc atgtccccgc cactcctgcc catcgacaag 21180 caccctggca ggcccgtcga atacccgccc gatgatgcgc cagccagaca gtgccgtacc 21240 ggcgaaacag gccaccaggg cgtggtcttc accgccaccc agcacccacg gccacggatc 21300 accgcccacc gcggtcgcgg ctgcaatcag cgcggcgtgg tctgcagcca gcgccgcggt 21360 ggataggtca atcgacaccc cggatgcccg cgcgacgtga cgcaggtcgg cgatcagacc 21420 gtcggagacg tcgatcattg cttgagcccc gcaagccgca gcagcaaccc ccttaccata 21480 tggcggctca ggcaccagat gacggcgccg cagatcatcg aatccgtcaa tccctttatg 21540 ccacagggca taaccggcag ccgagcgacc cagggcgcca gcgacagcaa ccatggagcc 21600 gtttttagcc ccagaccgca atactggtgc gcggccgtca agatcgccca acacggtaac 21660 ggagagcacc cattgaggac agctaactaa atcgccgccg acgatgccgg caccaatgcg 21720 cccggcctcg tcccacagcc catcgaccaa cgcgtccacc tgcgccaccg gcgtatcacc 21780 aggcgctccc aaacccacaa cgaatgtggt ggcccgcgcc cccatcgcct ctatgtcggc 21840 cgcgttctgc gcgattgcct tacggccgac atcgtgcggt gttgaccagt ccagccggaa 21900 atggcgatcc tgcaccaaca catctgttga taccacgatg cgaccgtcgc tggcagtcac 21960 caccgctgca tcatcgccgg gcccgagtgc gaccacagcc ggctgcctgc ggcctcgcac 22020 cagccggtcg attaccgcga actcaccgag ctgctcaagc gttacagact cccctaacgc 22080 cccacattca tggttgcaca cgtcacttcc tccggcgtgt cccggacctc tgaggccagc 22140 cgaacgatcg cccgaactgc gataagttaa atctctgccg acccgcacga gcggaccgcc 22200 gccagtgtag agccggatgc gtacggtaca cggcccgaca atcagcacaa caggaaggaa 22260 tcagtcatgg aggtggctgg gcaggtgacg agcaactccg acgctggttc tgctgtcgac 22320 gcaggcgggc caccacgcac cgtgattatc gccgcagtgg tgctgacagc agcaacgatc 22380 ggcacaatct tggtcctcgc agcaaccctc cacgagccac cacagccagt tgtcattact 22440 gccgtcccag ccccgcaggc caccactgcc gcatgccgat cgctgacgca agcactgcct 22500 cagcggctcg gcgactatga gcgtgcacct gtcgcgcaac cagcgcccga cgccgtagcc 22560 gcctggcgaa ccggctcaga caccgagcca gtggtgctgc gctgcggact cgacggccca 22620 gccgaattcg ttgtgggttc cccaatccaa gccgtcgatc aagtgcagtg gtttgaggtg 22680 gacgccaaac caaaacccgc cattgatgcc ggcagatcca cctggtacac agtagaccga 22740 ccagtgtatg tcgcattgac actgccatct ggatcgggac cgacacccat ccaagaactc 22800 tccgacgtga tcgaccggac cttggcggcc atcccgatca gcccggctca gtctcactag 22860 cgagcatgct aacgcatacc cacaccccga gccaatgccg tatccaccat ggtcgctagc 22920 aacgtcgggt agtccacgct actgaccgcc cacagctttg ggtacatcga ggtcatggtg 22980 aaccccggca tcgtgttgat ctcattgatc accggcccgt cgtcggttag gaaaaagtca 23040 actcgtgcca ggccctggca gtcgatagcc cgaaacgcct gaatcgcgag ctggcgcacc 23100 tcgtcagcaa cgtcatcgtc caccttggcg ggcacatcta actcggctgc gtcgtcgaga 23160 tatttggtgg tgaagtcgta gaacgaatcc tcgcttccgc tcaccccggc tacccgaatt 23220 tcccccaccg cgctggctgc cacagtgcca tccggcattt cgagcacgcc gcactccagt 23280 tcgcggccgt taaccgccgc ctcgacaatc accttcggat cgtgccggcg agcgtaggca 23340 atcgcggagg gcagttgacc ccagctcgac acccggctga taccgataga cgagccaccg 23400 cgtgcgggtt taacgaatac cggtaaactc aaccgctcac actcctgccg atgcagcgtt 23460 ggccgcaacg gacgcaacac cgtgtacgcg ctcaacggca gtccctccgc agcgaagagc 23520 ttcttagtga attccttgtc catgccggcg gcgctggcca gaacaccagc tccgacgtag 23580 ggcacacgag cgagttccag cagcccctgg atggtgccgt cctcgccata tggaccatgt 23640 aacaccggga ataccacatc gaccgacgtc aggacctctc cggccccaag gccggcgccg 23700 tgtgaaagtg acaccagttg accgctgcgc cgtggatcgg ccggcagcgt caactcgatt 23760 cccgattcgc agctcacagc gggaagctgt ctattggcaa tcgccagcgc atccgggttg 23820 ggatcggtga gcatccacgt cccttccgga gtgataccaa ccgcgaccac gtcaaaccgc 23880 tgtcgatcca gattgcgcaa gatgctgccg gcagacagac aggagacggc gtgttcgtta 23940 ctgcgcccgc cgaatacgac ggcaacgcgc acacggccgc cggatggcag ccaaggcatc 24000 aagggccgct ggtagacatt cacagcctaa agaggctacc ggtcaagcag ctccaagagc 24060 agctaaaact ctgaactagg ccttctaggc tactcacggt ccacctgggc gggccccgtc 24120 acattccggc gtggttactc agacttagta ctgcggccca acagcagagc catcgccttc 24180 tcgaccgaga gtcccttgtg acaaactcgg tggacggcgt cagttagcgg catctcgacg 24240 tcataactgg acgctagcgc gagtaccgac gcgcacgacg tcacaccctc gacgacgtag 24300 ccgtctccgc catcggaacc atccataccg tgcaagatcg actgcatgat ctcgccccgg 24360 cccaagcgtt cgccgagtga ccggttacgc gaatgcggcg atgtgcaggt ggccaccaaa 24420 tcacctaccc ccgccagacc ggccaacgta gtaacctggg cgcctagcgc catccccagc 24480 cggatgatct ccgccaggcc ccgagtaatg atcgtcgccg cggtgttttc gccgaacccg 24540 acacccgcag ccatcccgca cgccagcgct atgacgttct tgcatacccc gccgatctcg 24600 gtgccgacga catcgctgtt ggtgtacggc cgaaagtagc cactgcttag catgcgctgc 24660 aaagcgacgg ctcggcccaa gtcgctgcac gcgatgacgg tggctgcggg ctggcattga 24720 gcaatctcgc tagccaggtt gggtcccgaa agcaccgcga cctgcgccgg gtccacgcca 24780 gttaccgaga caatgacctg actcatccgc atcagcgtgc ccagctcgat gccttttgcc 24840 agactcacca gggtcgcgcc gtcggccacc aaaccacccc accgctcgag gttggcccgc 24900 atccgctgcg ccggcacccc caatagcacc gtcgacgcac cgcgcagcgc atctgctgga 24960 tcggcggtag cgcggatacc tggcggaagc agtgttcccg gtagataggc gcggttacat 25020 cgggtggtat tgatccgctc agcgacatcc ggtcgccgag cccacaatac gactccggcc 25080 tccggtccgc cggcatcgat aagcaccttg gccagtgcag tgccccatgc accagcgccc 25140 atcaccgcga cagcactctc tgaacggacc actatgccgg ccatctccac cacccccgta 25200 gttgtttaaa gcggcatctg cagcaggtac ggcacagacc aacacgggct atcgtcacgc 25260 tagtcacgat cacgcgctaa cgtggcgctg ggctgcggtc gttactctat cggtaagtcg 25320 tatcggtgat acgtggatca ggcagcttgg tcgatgtcgg cctcatattt ccagcggtca 25380 gactttaggt gcgttatagc aaatccgtga aactaagatt ttgctggtag gggcgtcgcc 25440 gatccctatg aagaccagcg tcacgctcct gtcgatcaac acggaagtgt attgtgacac 25500 ttcctgttcc aatcgaagtc taatatcgag ctggcagatt cggccgccgc ttcgggcata 25560 cagtcggctg ctgggttggt cgtcgagact gcagtgccga tacccaagtt agacttggga 25620 atcgccagtc ataccacgac acaacactct agcgcgcaaa tcgactgcca cggtcgagct 25680 ctcgtgacac ttgcagggaa tgcagcgacc aacgctggca ggatgacctc atgagtggca 25740 cacgggctgg aggcacagct gatgtcggct tgatcatcgc cgttaagcgg ctggccgccg 25800 ccaagaccag gctaggaccg gtcttctcga ctcggacacg agagaatgtg gtgttggcca 25860 tgttggtaga caccctgacc gcagcggcac ccgtttcagc actacgttca atcaccgtca 25920 tcacgcccga tgaggccgct gccgcggcag cggccgaatt cggagccgag attctggccg 25980 atccaacacc cgatggtcat ggtgatccac tgaataacgc cattgccgct gcggaacacg 26040 cgatagctgg atcattctcc aatatcgttg tactgcaagg agatttgcct gccttacaga 26100 cacaggaatt gtccgaggca atcgctgccg cccgacacca tcagcgcagc ttcgtcgctg 26160 atcgactggg tagcggaacc gcagcgctct gcacgttcgg aaccgcactc aacccgcagt 26220 tcggtccaga ttcatccgcg caacatcgcc gttcaggcgc gatcgagctt acgggaccct 26280 ggcctggcct gcgatgcgac gtcgacacgc ctgccgatct ggccgccgca cgccgtctgg 26340 gcatcggagc cgccaccacg cgggtggtcg cacatcttta gccccaacca gctacaggat 26400 cccaaatggt aaacagcaca ccaacgcgga atgaatggcc acagcgtgat agcagcacca 26460 tcggatgatg agcaatgatc ttttggtgac cgacatcgaa gctgaggccc gtaccgaaga 26520 gaatatatgg cattcagaca actccgccct cgcagcaccg cccgcggcga ccacctctgc 26580 gagtcaggac cagctgcccg acgaccgcta cctcaaccgg gaatcaagtt ggctggattt 26640 caatgcgcgt gtgctcgcac tagccgccga taactcgttg cctttgttgg agcgagccaa 26700 gtttctggct atcttcgcat ccaatctcga cgagttctac atggttcgag tcgccggcct 26760 caagcgccgc gacgagatgg acttgtcggt gcgctctgct gacggtctca ccccacgtga 26820 gcaactgagc cgcataggcg agcagaccca atggatcgcc agccggcacg cgcgggtgtt 26880 cctcgattcg gtgttacccg cactcggtga ggagggtatc tacattgtca cgtggacgga 26940 tttagatcag gccgaacgtg accagttatc gacctatttc aacgagcagg tcttccccgt 27000 cctgacacca ctggctgtcg atcccgccca cccgtttccg tttgtcagcg ggttaagtct 27060 gaacctggct gtcaccgtca agcaacccga agacggtacc cagcatttcg cccgggtcaa 27120 agtgcctaac aacgtcgatc gattcgtaga actcgctaac cgcggggcgg tcagagatac 27180 ctctgccgga gatgaaggtc agctcattca ccggttcctg cccatggagg agctgatcgc 27240 ggcattcctt ccggtgctct tccctggcac ggaaatcgtc gagcatcatg cattccgcat 27300 tacccgcaac gctgacttcg aggttgaaga agaccgtgac gaagacctac tacaggcgct 27360 ggaacgagaa ttggcgcgtc gacggttcgg ttcgccggtg cgactcgaga tcgccgacga 27420 catgaccgag agcatgctgg aactgctgtt gcgggaactc gacgtgcatc ccagcgacgt 27480 catcgaagtg cccgggctgc ttgacctgtc gtcgttgtgg caaatttacg ggctggaccg 27540 acccgcactc aaagaccgcg cattcattcc cgacactcat cccgctttcg ccgaacggga 27600 aactcccaag agcatcttcg cgacgctgcg cgaaggcgat gttctggtgc accatcccta 27660 tcactcgttt gccaccagcg tgcagagatt cattgaacag gccaccgccg accccgatgt 27720 gctggcgatc aaacaaacgc tgtaccgcac ctccggtgat tcaccgatcg tgctggcgct 27780 catcgaagct gccgaggcag gaaagcaagt ggtggcactg gtcgaaatca aggctcgctt 27840 tgacgagcag gccaacatcc ggtgggcgcg cgcgctggaa cacgcaggcg tgcatgtggt |