 |
|
EBI DbfetchID AL033502; SV 1; linear; genomic DNA; STD; FUN; 39871 BP. XX AC AL033502; XX DT 10-NOV-1998 (Rel. 57, Created) DT 14-NOV-2006 (Rel. 89, Last updated, Version 3) XX DE C.albicans cosmid Ca38F10. XX KW acetyl-coenzyme A synthetase 1; acs1; hem3; hem4; KW isocitrate dehydrogenase pseudogene; kinesin-like protein; KW membrane protein; porphobilinogen deaminase; RPS region; KW serine-threonine protein kinase; uroporphyrinogen-III synthase. XX OS Candida albicans OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; mitosporic Saccharomycetales; Candida. XX RN [1] RP 1-39871 RA Oliver K., Harris D.; RT ; RL Unpublished. XX RN [2] RP 1-39871 RA Barrell B.G., Rajandream M.A.; RT ; RL Submitted (09-NOV-1998) to the EMBL/GenBank/DDBJ databases. RL On behalf of the pilot sequencing project on the Candida albicans strain RL 1161 genome. Sanger Centre, Wellcome Trust Genome Campus, Hinxton, RL Cambridge CB10 1SA E-mail: barrell@sanger.ac.uk Cosmids supplied by Prof. RL Duncan Shaw, [3] Department of Molecular and Cell Biology, The Institute of RL Medical Science, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, RL UK. XX RN [3] RC Article No. FG970983 RP 1-39871 RX DOI; 10.1006/fgbi.1997.0983 RX PUBMED; 9290243. RA Tait E., Simon M.C., King S., Brown A.J., Gow N.A.R., Shaw D.J.; RT "A Candida albicans genome project: cosmid contigs, physical mapping, and RT gene isolation"; RL Fungal Genet. Biol. 21(3):308-314(1997). XX CC Notes: CC CC Funding: sequencing funded by Beowulf Genomics Ltd. CC CC CDS are numbered using the following system eg CAC20C1.01c. CC CA (C. albicans), 20C1 (cosmid name), CC .01 (first CDS), c (complementary strand). CC CC The more significant matches with motifs in the PROSITE/PFAM CC database are also included but some of these may be fortuitous. CC CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC CC Cosmid Ca51G1 which is wholly contained in cosmid Ca38F10 differs at CC positions 9129, 14040, 19941 and 20056. XX FH Key Location/Qualifiers FH FT source 1..39871 FT /organism="Candida albicans" FT /strain="1161" FT /mol_type="genomic DNA" FT /clone="cosmid Ca38F10" FT /db_xref="taxon:5476" FT misc_feature 1..1986 FT /note="repeated region with positions 2451..4436" FT misc_feature 1465..1987 FT /note="BLASTN match to (score: 2552, strand: (+1), range: FT 1-523) D63856 C. albicans DNA, RPS region." FT misc_feature 2451..4436 FT /note="repeated region with positions 1..1986" FT misc_feature 3915..6424 FT /note="BLASTN match (score: 5848, strand: (+1), range: FT 1-2488) to D63856 C. albicans DNA, RPS region." FT CDS 6054..6428 FT /pseudo FT /partial FT /transl_table=12 FT /product="hypothetical protein " FT /note="Ca38F10.01, probable pseudogene orf, len: 124 aa, FT RPS orf similar to region of isocitrate dehydrogenase eg FT IDH1_YEAST isocitrate dehydrogenase (NAD), mitochondrial FT (360 aa), fasta scores, opt: 224, E(): 4.1e-23, (41.4% FT identity in 140 aa overlap)" FT /db_xref="PSEUDO:CAA21998.1" FT misc_feature 6797..9734 FT /note="region similar to CALAMCA3B L11068 Candida albicans FT lambda Ca3 /B fragment" FT variation 9129 FT /replace="c" FT /note="difference with sequence of cosmid Ca51G1" FT misc_feature 9747..10209 FT /note="repetitive region, contains 5 degenerate repeats" FT variation 14040 FT /replace="a" FT /note="difference with sequence of cosmid Ca51G1" FT CDS 14258..15280 FT /transl_table=12 FT /gene="Ca38F10.02" FT /product="Porphobilinogen deaminase" FT /note="Ca38F10.02, hem3, len: 340 aa, similar to HEM3 or FT YDL205C or D1057, HEM3_YEAST Porphobilinogen deaminase (EC FT 4.3.1.8) (327 aa), fasta scores, opt: 1204, E(): 0, (59.8% FT identity in 321 aa overlap), contains PS00533 FT Porphobilinogen deaminase cofactor-binding site" FT /db_xref="GOA:O94048" FT /db_xref="InterPro:IPR000860" FT /db_xref="UniProtKB/Swiss-Prot:O94048" FT /protein_id="CAA21999.1" FT /translation="MPHHIMSINDSNHVQIGGRKSKLAVVQSEIVKKVIEDTFPNLSCS FT ILALSTLGDKVQTQPLYTFGGKSLWTKELEILLLDSVDEFPKLDLIVHSLKDMPTNLPE FT EFELGCIFQREDPRDAIVMKQGSSYKSLKDLPAGAIVGTSSIRRSSQLIKNYPHLRFES FT VRGNIQTRLNKLDQPNNEYCCLILASAGLIRLGLGHRITSYLDDMYYAVGQGALGIEIR FT KGDDNIKSILKKIEDPIATICCLAERSLMRYLEGGCSVPLGVHSDYNESKQELTLKGII FT VSPDGTVSIEDEVIKRITCDEDCEQVGIELGDKLKAKGAKEILDKIDMTRNINARPTEV FT " FT misc_feature 14996..15046 FT /note="PS00533 Porphobilinogen deaminase cofactor-binding FT site" FT CDS 18430..20457 FT /transl_table=12 FT /gene="Ca38F10.03" FT /product="acetyl-coenzyme A synthetase" FT /note="Ca38F10.03, acs1, len: 675 aa, similar to ACS1_YEAST FT acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (713 aa) fasta FT scores, opt: 2991, E(): 0, (67.8% identity in 645 aa FT overlap), also to ACS2_YEAST acetyl-coenzyme A synthetase 2 FT (EC 6.2.1.1) (683 aa), fasta scores opt: 2449, E(): 0, FT (59.2% identity in 666 aa overlap), contains PS00455 FT Putative AMP-binding domain signature, Pfam match to entry FT PF00501 AMP-binding, AMP-binding enzymes, score 325.60, FT E-value 5.5e-94" FT /db_xref="GOA:O94049" FT /db_xref="InterPro:IPR000873" FT /db_xref="InterPro:IPR011904" FT /db_xref="InterPro:IPR020845" FT /db_xref="UniProtKB/Swiss-Prot:O94049" FT /protein_id="CAA22000.1" FT /translation="MPESTQQSHLSLDHEKMQQPPKGFTERSKTKPNLADFETYQKLYK FT QSIENPNEFFTQQAKENLDWFKPFDLARFPVDPKDDYKNGDLPAWFINGQLNACYNAVD FT RWAIKNPDKPAIIYEGDEPDQGRIITYGELLKQVSKLAQALTKLGVKKGDSVAVYLPMI FT PEAIVTLLAIVRIGAMHSVVFAGFSSASLRDRILDADSRIVITADESKRGGKTIETKKI FT VDDALKECPKVRNVIVFKRTGNSHVPFSPGRDLWWHDEMAKYGPYFPPVPVNSEDPLFL FT LYTSGSTGKPKGVQHNTAGYLLGAVLTTKYTFDVHEDDILFTAGDIGWITGHTYCVYGP FT LLAGATSVVFEGTPAYPNYSRYWEIVDKYKVNQFYVAPTALRLLKRAGTKYVEKYDLSS FT LRVLGSVGEPIAAEVWHWYNDNIGRGQAHIVDTYWQTESGSHLLTPLAGITPTKPGSAS FT LPFFGVDPKILDPTTGEELPDNDVEGVLAIKSAWPSITRGIYNDYNRFIDTYLAPYANY FT YFSGDGAARDRDGFYWILGRVDDVVNVSGHRLSTAEIEAALIEHPIVGESAVVGYADEL FT TGQAVAAYVSLKKDKAVGEDVENIKKEMILTVRKEIGPFAAPKMILLVDDLPKTRSGKI FT MRRILRKVLAGEEDQLGDISTLSNPGVVQQIIDVVHHAKK" FT misc_feature 18817..20136 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzymes, score 325.60, E-value 5.5e-94" FT misc_feature 19270..19305 FT /note="PS00455 Putative AMP-binding domain signature" FT variation 19941 FT /replace="a" FT /note="difference with sequence of cosmid Ca51G1" FT variation 20056 FT /replace="g" FT /note="difference with sequence of cosmid Ca51G1" FT CDS complement(20720..21535) FT /transl_table=12 FT /gene="Ca38F10.04c" FT /product="uroporphyrinogen-III synthase" FT /note="Ca38F10.04c, hem4, len: 271 aa, similar to FT HEM4_YEAST uroporphyrinogen-III synthase (EC 4.2.1.75) (275 FT aa), fasta scores, opt: 632, E(): 9.5e-31, (41.5% identity FT in 277 aa overlap)" FT /db_xref="GOA:O94050" FT /db_xref="InterPro:IPR003754" FT /db_xref="UniProtKB/TrEMBL:O94050" FT /protein_id="CAA22001.1" FT /translation="MTNVILLKNASIPCDPYDIKFSNSNKYKPNFVPLLTHRHKDKSQT FT LSFLISDEFLNNIPIFIITSQRAVEMFKECIEELNHDIRQRIYQKIGYTVGPATYKILK FT SVGFKDVRGGDEAGNGSKLADLIKQDTIGRENIPMVFFTGVIRKDIIPRKLIDSGYNNF FT QEFILYQTGDRLDIIDNFKKVIHGLDKDKDNDDVWIVFFSPQGTKEIVNYLIDRDGNSN FT QKNWKIASIGPTTRDYLKDFDLSPHVIAPKPDPEALFETIFQYDKTYAL" FT CDS 22800..23258 FT /transl_table=12 FT /gene="Ca38F10.05" FT /product="hypothetical protein" FT /note="Ca38F10.05, unknown orf, len: 152 aa" FT /db_xref="UniProtKB/TrEMBL:O94051" FT /protein_id="CAA22002.1" FT /translation="MKFFTAATTALLLSAQALAELTSYKLYAKSENTEVDGKGVSILHE FT GAGIYFVFLGTESIDVTYDDVEKLLYVPVSSDIQFNFGTNADIVQFSVTPPVSVEIAED FT GSVNFEGSDDLFAAQYINDPYNYSKDSYAVILRGKPHAIPIKLVAKKN" FT CDS 23553..24878 FT /transl_table=12 FT /gene="Ca38F10.06" FT /product="hypothetical protein" FT /note="Ca38F10.06, conserved hypothetical protein, len: 441 FT aa, similar to Q08646 S. cerevisiae chromosome XV ORF FT YOR242C (371 aa), fasta scores, opt: 439, E(): 9.3e-12, FT (38.6% identity in 220 aa overlap)" FT /db_xref="UniProtKB/TrEMBL:O94052" FT /protein_id="CAA22003.1" FT /translation="MLKSIKRSDSYLLESSSSNNSTSNIITTSTNNTQNSLLKRTTKPN FT VSSTRAPSFTFSRLLSEDTFNYNTNSNSNNTNIHNPNNNNSKYSTIHGISSSSRRNNFL FT KVCSWPFTKIESFHDSITKNDNDNDVDNDNIVEFADDQSTLGNDDGNTKHLTIADYSNI FT KRKNFGGLISDSNGSGNGIHGYNYTLGGPNNGSSGPLTGINPSLENINHVANEKFHKVF FT NRVKRPPVEQNNKRRCVLLSNLNESMGLNSVLQQVCGGPLEKLTVLSNGKIELFFIFPE FT HAKQFYTYGKATGLLMVNGVKLKVEWLNDENNLVNSTLSSSLMSDILHNGCRRCLIISK FT NIPGKRIRNGDKMFYPEPDIHYSTNLNFEEIKNDFNKFGKVLDIGSVISRKLCFSVFYY FT DIRCAILAKQELDLIGSELNKKYKDWSIWYGKDITDRACFVL" FT CDS 25257..27254 FT /transl_table=12 FT /gene="Ca38F10.07" FT /product="kinesin-like protein" FT /note="Ca38F10.07, kinesin-like protein, len: 665, similar FT to eg S. cerevisiae, KIP2_YEAST kinesin-like protein KIP2 FT (706 aa), fasta scores, opt: 429, E(): 0, (34.0% identity FT in 726 aa overlap), contains PS00017 ATP /GTP-binding site FT motif A, Pfam match to entry PF00225 kinesin, Kinesin motor FT domain, score 246.90, E-value 2.7e-70" FT /db_xref="GOA:O94053" FT /db_xref="HSSP:1F9V" FT /db_xref="InterPro:IPR001752" FT /db_xref="InterPro:IPR019821" FT /db_xref="UniProtKB/TrEMBL:O94053" FT /protein_id="CAA22004.1" FT /translation="MSHKTPTRARSCYANSSTTSMNSTPSRNSFRPPSRLSLIPRSSSP FT IQPPRSRPSSAMSISRPSTPSMKSQEPYTGAITVSIRPNPNTIDNKNWSIDEFDNSIIN FT TTDGTRFVFDNVFPMDRQLSNIQVYNKSCYNVVNKFLEEGYNGTIFAYGMTGSGKTFSM FT KGCENDPGFVELAINDIFQKINDNTTTKKYKMDISYLEIYNEKIIDLLSGSPSSQTTSQ FT SNQDLKIRDDVDFGTKVVGLTSANISSKPQLLQLIKYGDTNRKTSATDFNARSSRSHSI FT LQIRLQVIDLLTETELKSTLSLCDLAGSERAATSLERRKEGSFINKSLLALSNVINKLS FT SSALEHIPYRDSKLTRLLQPALSGSSLVSILCTIHMGGNQQNSQQCVAETYKTLRFAAR FT AKDIVINVEKNMSHKLDGGDSSKMIQELNEIISKQRQEIIKLQSNTGVSSKEFENSRIV FT QLESENRVLIEKLDHLTRLTDLQKTETAIIKNDILNDILSSGLDNSQILMTNIEDFYKK FT MTYEANEYKSYICRLETQLRLESINSTQQQQSSSPTSSIPMTNTTNDSSELMDALKEQE FT EEILMLKEQLKDKDQIIKSLSQTTRLRRLVGNNSNSIANSHNTYNTLDNDFKRHTTIVN FT FDKENYEPELRDFKLSPKKPKSNCDILESF" FT misc_feature 25554..26477 FT /note="Pfam match to entry PF00225 kinesin, Kinesin motor FT domain, score 246.90, E-value 2.7e-70" FT misc_feature 25713..25736 FT /note="PS00017 ATP /GTP-binding site motif A" FT CDS 27826..29046 FT /transl_table=12 FT /gene="Ca38F10.08" FT /product="hypothetical product Ca38F10.08" FT /note="Ca38F10.08, unknown ORF, len: 406 aa, but start site FT and /or splicing uncertain, contains PS00125 Serine FT /threonine specific protein phosphatases signature" FT /db_xref="UniProtKB/TrEMBL:O94054" FT /protein_id="CAA22005.1" FT /translation="MFKKLRSNSTVSHNRRTSTSDSQQQSVRGNHELRRHSQPNPIINY FT EVLHSTSTANGRNHIRQNESESVIIDESTDQEMSPLTTTQSNQSTALSEANTLFIDRHQ FT RLELQDNYLDNFTMYLPFVIRQMRLIEERRYLESQEYRNENEQTSDNNDPLQQQQQQQQ FT QQQTSRHVVIPDITGDDLDDISTIFDEAHVPLETFAMNHYKILEKQLSSFDIKRSFIIV FT AGMLKHNTYIFPSAESFELFKQLRSSIKKHRKNSIMVYDNQGTIKRASLTSSTTNIKRE FT DINQESEGIIIDDRPHIIPLDQKLKGLGLPLFKIQTPYLSSFRKNTPCIIFKRYKEVPQ FT PPPAPPPASPASSSSTPSLLLASSSSTSSLASSLPGKIKVKKSPSKSSDEYTSSKDDFE FT FETYNFC" FT misc_feature 27904..27921 FT /note="PS00125 Serine /threonine specific protein FT phosphatases signature" FT CDS 29128..29865 FT /transl_table=12 FT /gene="Ca38F10.09" FT /product="hypothetical protein" FT /note="Ca38F10.09, unknown orf, len: 245 aa but start site FT and /or splicing uncertain" FT /db_xref="UniProtKB/TrEMBL:O94055" FT /protein_id="CAA22006.1" FT /translation="MFQSNLRPFADFLYKKTRFRVIGPAMLSGVIQNYNPHMRLLVIDD FT DKPSLVDNIINKKPHSGSNTSIATVATNSITGAAAAAAGGLFHKRKSNDKKSKTYVEFN FT YDDPTTFINPIPNNTFADEDNNANIGQAINTSSYISNDLPPFGCFKDSMLYRTNSSLLP FT KKYTEEGKIQMYQDKSFLIDKDENSTLSIDIDSMVLVCIMATLRDISIKNAGRTNTQRT FT FGIGLGNRIGYGLEPSHVGIIGL" FT CDS complement(join(30095..30809,31652..31728)) FT /transl_table=12 FT /gene="Ca38F10.10c" FT /product="hypothetical protein" FT /note="Ca38F10.10c, unknown spliced ORF, len: 263 aa, FT gly-rich repetitive protein, contains PS00017 ATP FT /GTP-binding site motif A" FT /db_xref="GOA:O94056" FT /db_xref="InterPro:IPR000504" FT /db_xref="InterPro:IPR012677" FT /db_xref="UniProtKB/TrEMBL:O94056" FT /protein_id="CAA22007.1" FT /translation="MPKNTLYVTGFSRESKAADLAPDFEKYGELVRLDIPPPRSDDGEK FT YAFVEYKDAESCERALELDGKTLPYSIKDGLVVQVARSDPYRVRQQFSGPRGGYRDGGY FT GGRGGYRDGGYGGRGGYRDGGYGGRGGYGGGRGGGYGGYRDGGRGGYRDGGRGGYGGYR FT DGGRGGGYGGYRDGGRGGGYRDGGYRDGGYRDGGRGGYGGGRGGYDRDREEGRGGYDRE FT EDRGGYERDEGREPRVEERRYSRSPSRSPPRRDRSRSPERY" FT misc_feature complement(30686..30709) FT /note="PS00017 ATP /GTP-binding site motif A" FT misc_feature complement(30810..30812) FT /note="tag, splice acceptor for Ca38F10.10c" FT misc_feature complement(30838..30844) FT /note="gactaac, splice branch sequence for Ca38F10.10c" FT misc_feature complement(31646..31651) FT /note="gtatgt, splice donor sequence for Ca38F10.10c" FT CDS 33395..35614 FT /transl_table=12 FT /gene="Ca38F10.11" FT /product="hypothetical membrane protein" FT /note="Ca38F10.11, SPT23 homologue, len: 739 aa, potential FT membrane protein with C-terminal transmembrane domain. FT similar to S. cerevisiae YIR033W., YIV3_YEAST, hypothetical FT 127.0 kDa protein (1113 aa). Fasta scores, opt: 391, E(): FT 0, (35.0% identity in 580 aa overlap) and SPT23 OR YKL020C, FT SP23_YEAST SPT23 protein (1082 aa), fasta scores, opt: 372, FT E(): 0, (36.6% identity in 599 aa overlap), contains Q-rich FT region, N-rich region" FT /db_xref="InterPro:IPR002909" FT /db_xref="InterPro:IPR014756" FT /db_xref="UniProtKB/TrEMBL:O94057" FT /protein_id="CAA22008.1" FT /translation="MTDPLTFLDEFNEFFYFPEDNDTFAPNEIGKLKFGSKINATPKSI FT EVPSSYLDFSPETMNNLPYRLSISGLPSFSRVETQIKMNLTINAPFTNHYVHITPDLIS FT KKKLCLEEPYSNLDDNIKKHILEFDAYILTQSNKSCAVCPRCIKREQKRASRSKAGEEK FT SAVWDCDVERKAIIINNKEIIAFQSGVLELSARIICYCRHHKESEGFKLLIVLKNHLGQ FT VVAKQISSPIMIMDRKKNLKDSAPSSSANLVELDKKKLSISDSDNEKLMTNQFVQLSPN FT SLDESASEALATTDYETRGVKRKKLSVDDSFNTTSNPMYNGFSGYSPMSNSDTNTSAIS FT QSFSGPTISKPSSAQFSIGFSPISQPQFPSQFQSQTQLLQQQQQQQQQQQQQQQQQTVP FT SIQKIIPAQGSIRGGIEVTILGFNFRPGLSIKFGANQALATHCWSETTIVTYLPPAAQP FT GQVLVTFENQDNDNVGGPQQQQVFTYTDDTDRQLIELALQIVGLKMNGKLEDAKNIAKR FT IVGTDNNNNNNNNSSNINTNTSTNSNSPADNENDNNNTNNNTTAGAAGAAAPGAAPGST FT VTSTNSNTFSSFENDEKSMAKLNKLVEFFESRTNNQDDLEKWSSMKTSEIFGDQEEEYF FT ADSEVVPSYKSIFPNGGNANNTKLIAEPTPEADAGATSDSSEDMVVTYINHPRKSMKND FT KMLLFFWIPALVIMLFTFFMVYVVGYQLNDYSIVEKMLNCTSLLR" FT CDS complement(35897..38140) FT /transl_table=12 FT /gene="Ca38F10.12c" FT /product="hypothetical protein" FT /note="Ca38F10.12c, hypothetical protein, len: 747 aa, FT similar to YOR243C or O5254, YO43_YEAST hypothetical 77.0 FT kDa protein (676 aa), fasta scores, opt: 928, E(): 0, FT (43.4% identity in 730 aa overlap)" FT /db_xref="GOA:O94058" FT /db_xref="InterPro:IPR001656" FT /db_xref="InterPro:IPR011760" FT /db_xref="InterPro:IPR017091" FT /db_xref="InterPro:IPR020103" FT /db_xref="UniProtKB/TrEMBL:O94058" FT /protein_id="CAA22009.1" FT /translation="MSESLKRSFPQDQEILATQTNLINDGSGSSSNVAKKLKPTLMGIS FT ETKAGITQFINPNITGFSGLLKTLHSDFQVNEIDPLGNVIHLIDDGIDVGPSKRELKLQ FT ERAKFRQEIEGKTEEEIAEIKAAKQQEKEQQQRSKEADDNGGDGGESNKHPKISDEDRE FT ELLKFITVEELKQVEQLFHNGKNFETETKFDDKEQRTKLHQLFRKVFQNKLETITSSEN FT TFKIAISSRNRNGGSRQQPRQFQESMHHIDENGVINYGLGPYKPYLHFTVYKQNRDTME FT VANNIGKLLRINHKFINYAGTKDRRGATCQRFSINHGKVLRVNALNKSKRNGFTLGSFS FT YEDHPLKLGDLKGNEFTIVIRDIKPHHQQQQQQEQQPQDQSQSIESIVTSCFESLQKNG FT FINYFGMQRFGSFSISTHEFGKFILNENWQEFVELLLSDQESVAPGSIEARKIWKQTRD FT PKLTLNKLPHYFVAETAVLRVLQNESPQQKDDNNTVYSSNSYLKAIQAIPKNLRMMYGH FT AYQAYIWNLVASKRIELYGLNLIEGDLVFEDPITNPDIVDEDVVYLNEAKVRSLTKQDI FT ESGKYTIFDVILPSPGYKIEYPTNPILKQVYIDIMEKDGLNPFKMIRKQKEFSLTGTYR FT KLMAKANNLSFELIKYKTEEGEDGETGDGEKPLIRTDLELLNLKKEQEKKSSQKSVTTP FT IELPDRIINDDKEGGNKLAVVLRMQLGVSSYATMALREFMRIDTSRYRDGLCK" FT CDS 38836..>39871 FT /partial FT /transl_table=12 FT /gene="Ca38F10.13" FT /product="serine-threonine protein kinase" FT /note="Ca38F10.13, partial orf, len: >345 aa, Serine FT /Threonine protein kinase, similar to eg KCC2_YEAST calcium FT /calmodulin-dependent protein kinase type II (EC 2.7.1.123) FT CMK2 or YOL016C, (447 aa), fasta scores, opt: 1372, E(): 0, FT (57.2% identity in 339 aa overlap), contains PS00107 FT Protein kinases ATP-binding region signature, PS00108 FT Serine-Threonine protein kinases active-site signature," FT /db_xref="GOA:O94059" FT /db_xref="HSSP:1NXK" FT /db_xref="InterPro:IPR000719" FT /db_xref="InterPro:IPR002290" FT /db_xref="InterPro:IPR008271" FT /db_xref="InterPro:IPR011009" FT /db_xref="InterPro:IPR017441" FT /db_xref="InterPro:IPR017442" FT /db_xref="InterPro:IPR020636" FT /db_xref="InterPro:IPR020651" FT /db_xref="UniProtKB/TrEMBL:O94059" FT /protein_id="CAA22010.1" FT /translation="MSTDHHSHPVEGHQFKKIFNRLSGQPESYSRKQNYTFGKTLGAGS FT FGIVRYARDNSTDEEVAVKIILKKALKGNESMIIDEMQLLEQLNNPHIVGFRDWFESKD FT KFYLVTQLATGGELFDRIVQKGRFTEHDASLVVLQMLEALEYLHNKDIVHRDIKPENIL FT YLTSKDDSPIVLADFGIAKRLQNPNEKLTSSAGSFGYAAPEVILGTGHGKPCDIWSLGV FT VTYTLLCGYSPFRSENVQDFINEVKHNNAVIFHADYWKDVSKDARRFIIKALQFNPDNR FT PTATELLNDPWLVSIAKEYKETDLLPNFKQGFDAKKKFRQAIELVKLNNRIKKLKEWQT FT DEDDD" FT misc_feature 38938..39714 FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain, score 315.70, E-value 5.4e-91" FT misc_feature 38956..39039 FT /note="PS00107 Protein kinases ATP-binding region FT signature" FT misc_feature 39289..39327 FT /note="PS00108 Serine /Threonine protein kinases FT active-site signature" XX SQ Sequence 39871 BP; 13240 A; 6699 C; 6354 G; 13578 T; 0 other; gatctttgaa tgagcttgct ggcatcaaaa ttgatgtttt tctgtccaac ggatttaggt 60 ggcaaggcat cttggtgttt ttcgtcgaaa atttgttagg aaaaaaggga taaaaaaacg 120 gcctttttta ttgtagcatc tccaatcatt cgcctacctc aaccaccatc tgtgcgtata 180 ataaacattt gtcttggctt caaaacggta ttagtttggt ctttgtaacg cctctattgg 240 tcgagcagta gtcaaaataa aaacacgagt gattcttaac tatggccaaa acggcctttt 300 ttgtcccacg gtatgcagtt gtatctcttt tctaacagta tcccacggct ttgacactca 360 cattttgtgg ttccaaatcg atactagcct tgtcattaac tcattcaaat tcgatcttct 420 gtcaacaata tacataattt ttccctctta actatggaca aaacggcctt ttttgttcca 480 caggatgcag ttaaatctcg tttctaacag tgcttgcagg gatagaactc ataatccaaa 540 ggtataaatc ggcactagtt tgatttttgt agcgttgaat ttggtcgcgt agttgtgatc 600 agacatagct gcggctccct taactatggc caaaacggcc ttttttgttc cacagatagc 660 agttgtattt cgtttctaac agttcttgca gggatagaac tcataatcca aaggtataaa 720 tcggcactag tttgattttt gtagcgttga atttggtcgc gtagttgtga tcagacatag 780 ctgcggctcc cttaactatg gccaaaacgg ccttttttgt tccacagata gcagttgtat 840 ttcgtttcta acagttcttg cagggataga actcataatc caaaggtata aatcggcact 900 agtttgattt ttgtagcgtt gaatttggtc gcgtagttgt gatcagacat agctgcggct 960 cccttaacta tggccaaaac ggcctttttt gttccacaga tagcagttgt atttcgtttc 1020 taacagttct tgcatggtta gcactcataa gaaaaaggta taaatcggca ctagtttgat 1080 ttttgtagcg ttatttttca tcgcgcagtc ttcaacggac atcaccgcga attccttaac 1140 tatggcaaaa acggcctttt ttgttctaca gaaagcaatt gaaccttgtt tctaacagct 1200 cttacagtca tagtacttac atcttatggc tatgaactgg cactagttgg gtctttctag 1260 catcgaaact gactgtgtca gccttggcgg agttaatttc acatttccac ggagaaaacg 1320 ttttcttcaa tagctcaacc aattctgatc cgattcatgc ctaattcaca cccaatactc 1380 tacatgattg tagcttcaaa acggccctag tttggtcttt gtagcacatg tggttcatca 1440 gtaatcgttg tctatccact atgccccggg cacgaccttt tctgctcgat gcgaactttt 1500 tgccctcaac caatgaaaac aacactgaat aaatcaaaac tctcggatgc aaacactata 1560 acttgactct acaaatcggc actagagcca ccaaatacca acttcaattg gttgtgctac 1620 agaaaggggg tggtcttaac tatggccaaa acggcctttt ttgacccaga gatggaagct 1680 caactcttct tttgaccggt ttagacggat ttgaaaatgt ttattgttgg ctataaattg 1740 acaccagagc caccaaatac cagcttcaat tggttgtgct attagcaaac ggggttacca 1800 gggtgctctt aactatggac aaaacggcct ttttgctcct gcagcaccca actaattacc 1860 gttattaacg attctctcgg gttttaaaac cacaactgta ggccacaaat cggcacctga 1920 ttggctcttg tagccctcct ctacctctca cacttcaact ttccttctta actattgtag 1980 tttggatgca acttgaaaat attggttttt tgacaatatc tccaccaata ttggacttcc 2040 ttcgaccaaa cttagattga cagttgctta caaaatgcgc ctttaaagtg acccgacttt 2100 gggaagtcta gcacctatat tgacagagtt attaacgatt ttagactttt cctaacaatt 2160 ctggcccatt tggtagcgat ttttcaaaaa cgattgacca aaactaaaaa cacagcgtgt 2220 tcattcaata caccatctac attcaccata ttactggata tatacctaag aaacggtggc 2280 tacagattga taccaaaaaa gccatagttg gtctaacaaa aagttgctgt acagacaacc 2340 cccaattttc actatgtaaa tatccacctt aatcgcaatg gagcttcgaa tgtaccatcg 2400 attgttttca aaatctagtg gtttcttccc caaacatgta gcttcaaatt gatctttgaa 2460 tgagcttgct ggcatcaaaa ttgatgtttt tctgtccaac ggatttaggt ggcaaggcat 2520 cttggtgttt ttcgtcgaaa atttgttagg aaaaaaggga taaaaaaacg gcctttttta 2580 ttgtagcatc tccaatcatt cgcctacctc aaccaccatc tgtgcgtata ataaacattt 2640 gtcttggctt caaaacggta ttagtttggt ctttgtaacg cctctattgg tcgagcagta 2700 gtcaaaataa aaacacgagt gattcttaac tatggccaaa acggcctttt ttgtcccacg 2760 gtatgcagtt gtatctcttt tctaacagta tcccacggct ttgacactca cattttgtgg 2820 ttccaaatcg atactagcct tgtcattaac tcattcaaat tcgatcttct gtcaacaata 2880 tacataattt ttccctctta actatggaca aaacggcctt ttttgttcca caggatgcag 2940 ttaaatctcg tttctaacag tgcttgcagg gatagaactc ataatccaaa ggtataaatc 3000 ggcactagtt tgatttttgt agcgttgaat ttggtcgcgt agttgtgatc agacatagct 3060 gcggctccct taactatggc caaaacggcc ttttttgttc cacagatagc agttgtattt 3120 cgtttctaac agttcttgca gggatagaac tcataatcca aaggtataaa tcggcactag 3180 tttgattttt gtagcgttga atttggtcgc gtagttgtga tcagacatag ctgcggctcc 3240 cttaactatg gccaaaacgg ccttttttgt tccacagata gcagttgtat ttcgtttcta 3300 acagttcttg cagggataga actcataatc caaaggtata aatcggcact agtttgattt 3360 ttgtagcgtt gaatttggtc gcgtagttgt gatcagacat agctgcggct cccttaacta 3420 tggccaaaac ggcctttttt gttccacaga tagcagttgt atttcgtttc taacagttct 3480 tgcatggtta gcactcataa gaaaaaggta taaatcggca ctagtttgat ttttgtagcg 3540 ttatttttca tcgcgcagtc ttcaacggac atcaccgcga attccttaac tatggcaaaa 3600 acggcctttt ttgttctaca gaaagcaatt gaaccttgtt tctaacagct cttacagtca 3660 tagtacttac atcttatggc tatgaactgg cactagttgg gtctttctag catcgaaact 3720 gactgtgtca gccttggcgg agttaatttc acatttccac ggagaaaacg ttttcttcaa 3780 tagctcaacc aattctgatc cgattcatgc ctaattcaca cccaatactc tacatgattg 3840 tagcttcaaa acggccctag tttggtcttt gtagcacatg tggttcatca gtaatcgttg 3900 tctatccact atgccccggg cacgaccttt tctgctcgat gcgaactttt tgccctcaac 3960 caatgaaaac aacactgaat aaatcaaaac tctcggatgc aaacactata acttgactct 4020 acaaatcggc actagagcca ccaaatacca acttcaattg gttgtgctac agaaaggggg 4080 tggtcttaac tatggccaaa acggcctttt ttgacccaga gatggaagct caactcttct 4140 tttgaccggt ttagacggat ttgaaaatgt ttattgttgg ctataaattg acaccagagc 4200 caccaaatac cagcttcaat tggttgtgct attagcaaac ggggttacca gggtgctctt 4260 aactatggac aaaacggcct ttttgctcct gcagcaccca actaattacc gttattaacg 4320 attctctcgg gttttaaaac cacaactgta ggccacaaat cggcacctga ttggctcttg 4380 tagccctcct ctacctctca cacttcaact ttccttctta actattgtag tttggagttt 4440 gtgtcgtttt ttttggtggt caatacccta gagaattgta ggaatgagtg tttgctttgt 4500 aatgtgatgg gcattaagta tttctattgt taatacagta actataatac ttctgagctc 4560 tggctatctt gggatagttt ttatattgcg tagagatgag aactgatgat tttattaaag 4620 tctgtaatat taagtatggg aaggtggttg gttggtagca tttttgttga aatcgatggt 4680 gaaatatttt gatctccaat atctctgtta tttttctatt tgatattctc aaacttgcat 4740 taatgttaga tcggggatga gggaagaaag tgagagactg gggcgtgcag gggagggaaa 4800 atgagtgtgg tagtatcttt tccttctttg tctgaggtat tcccgagaat gcggagataa 4860 gagtacttgt ggcgggattg tgcaggattt tgtatgggaa aaatcacgtg acacggagac 4920 ggagttaagg gtcgtgtacc caagcccaaa aatacatagt aaatttgtta gggaaacgga 4980 gattagtttg tgtaatttcc gaagggtgcg gaaataattt ttgccataca aaattatttt 5040 tcttagtaaa ttttttagta cttttctagc actgcgattt ctattaaatc tattttcttt 5100 cacaactatt ttcttacacc caatttaatc gatctcatta gtacactata agacacaacc 5160 atttcaaaca ccacaagtaa tacaatacaa atcccaaata atacaaaaca aatcccaatt 5220 aattcaacaa ttgtttattc gaattaagat ccttttgaaa atgtattagc aatcccatta 5280 acgccattag tttcaatatt ttgtgatagc ggctagcggt ttccagtttt tgtttcggcg 5340 gaatgtctga tttatctagt ccaatcaaga gaatgaaaga gaggtatgat agtgaatcat 5400 tatcatttgg gagttacaga ggtaattgat taatggcgtc aagttataat tggtcatttg 5460 gtattgcatt ttgaagttcc cattaattta gacgctggtc cgttaatcta cctaatagtc 5520 atatttcaag tgatattcat aaatttacaa tgtaaatgtg ttttagagta atgtgtttgg 5580 cagaactagt cacacttggt attggtgtca tactcgtcta tttggtttgt tgtgtcagtt 5640 gttgcaaatt attgtctttc tgaaaattgg tttagttata ttaagagtaa gagtttgata 5700 gtattggtga ttggtcatat taagacttat ttgaaatata ccaggggatt attaaatgac 5760 tacagagtaa atgcatacca atttgcactt tcaggaacaa gagtgagacc atgccatatt 5820 gtccccctta tttgtcacaa agcattaatt gatataagct tggctttttc attttgggag 5880 ccatattagt tgctacattt tgaaacctca tgattgatat ttggaagtta ctttaattat 5940 tttgctagag attgaaatct gccaaaccat tgaatgttgc attcagagaa taatcagata 6000 ttgaaactta attagtttta atcaaaagca tttcacatac tattgatatt taagttggta 6060 ttgatttagg tttggtcaga gaaagtactg aagatgacta tagtgtgttg gaaaatcgat 6120 tatacctagg tgctgttgaa ttcttgaaaa ttatgacaaa atccaagtcc tacatatttg 6180 ttgaatacgc atttgatttt gctttgaaga acaacagaga attggttact gctatccaca 6240 aagctaaatt tttcaaattg ggctatggat tggtcaagac tactttggta ctgtggataa 6300 tgcttttata ccagctgttc tcaatccatg acaatccatt gttgtggccg tatggtttta 6360 tcctatccaa ttttggtgct gcattaatag atttcttgga tttggttcca ggtgctagct 6420 tttggtagaa gatgttctgt atttggccaa attgttgtca ccttgctttg gttattgaag 6480 ccaagaattc agaattggct tgatggtaat tcccatttta tggttcaatg catcttgctt 6540 ctggtgaccg acagatgaat actgaaatga attgtttaag gaagcttgaa ttagttggtt 6600 ctaatgcaat cttatgtgtt tctgaacggg atatattgtg gtccatatca gagagtggtt 6660 atttttaaac tggatcagaa tccaatcttc cttagtcacc tggttatacc gaaattcaag 6720 tgtttgtgga tattactact ttctcatggt tgatgttttg ggaaataaga atttaaaata 6780 tataccattg gatttgtcct gtaacgtgaa ggataagaat gattattgac atttggaaac 6840 taacccgata ttccattaac gagtaacaat cattttactg gcatctatac catttggaat 6900 ttccctagcc acaattcaaa gcctcagttc atgaaaatat tttgttgtta tattgcttct 6960 atcaagaaaa ccccggttta aataaaggaa aatattagta gatcatttac taattagtga 7020 agtaccgtat cctcatccat gttgatttgc tagattggtt tgccttcata catgctggct 7080 gtacaccaaa gaagtgttga taagagacta tcatcatcgc agagtttggt taagggaaag 7140 tgacgtgact taaactagtg ctgattcatg gctggtgtga taacctgata tggttgtatt 7200 atgcacatat tgacctggtt ataatcattg actgatgttg ttattgttag gttaagataa 7260 tgaagggcca accaactgct ataaattaaa attgtttaaa ctggatatca aactgggggt 7320 gtgttagaac aagcaaagtt ggaatataag catatgtgaa ttgtccattt agagagataa 7380 cccactggaa gtctattgct agttgtagtt atatagaatt tagtgtttac tactataata 7440 aatgttcata gttggtagta taatatagac attactgtag tttgtcagaa ttagatcatt 7500 cttattctac tagtaactca ggaaacactt tcatcagtcg ttgtccactg aactaggtct 7560 aagattctga ttttacttgc aattctagtt ccatcaagtt tctatggtgt gccactttat 7620 gcggatgtct acgtccaaaa aaaaagccac cacaaaattt tctcatgcat taaaatctat 7680 acttacctat catccacctt actctcttct aaactacatc aatcaattaa aatgatatat 7740 acactcgaag atagatgaca tggtattgat gaaaatgtgt tctattttgg ttttctgtat 7800 caaatattga tcgaaaagtt gggtgtacca gtgtcaacaa tcataagtgc tgcccgtggt 7860 atttgacgac cggcaggttg ccatgattat taataatatc ttctactact aataaatcaa 7920 aaaaaatact tctggattgt cctttggctg tctaagaaaa agttatgttt tgtctgatta 7980 tcaaattgtg atgggaactg tcaaacctgt tgcagaataa tatgggaaaa tcgtctaaga 8040 aatcttagtt aagaaggttt ttacaacatt tgaaaattga ccattcatga aattttagaa 8100 acatgacttc tatcagtgat aatgctagtg atgaagatgt attcggtgat ggatttgatt 8160 atcccaagac tacttgtcta tgattggatg ttaataatga gagtcattct aatttcaatg 8220 aagcatggtt tacaaattgg gaaagagtgt caatagttct gtcatattca ctatctatga 8280 gattataact atttcttttg aagttgttag taacaaaatg acaatgattg ttaatactat 8340 tagtgccaat agagtataga ttccattggc tgccatttta tcaattgggt acatttacta 8400 cttactttgg caaatcaatc aaaatggctt tgttataatg tttaagaacc ggtgggcaat 8460 aaatgatgtt atttttagtt tgatctaggg gctattaatt ttcatttccc aaccaagtta 8520 cgataaatga tatgtgtttg gacactattc acatattacc atgatgttca ctggtacttg 8580 agctaagtgt aagttcaaga gacatctaat accaccttgt atatttaagt taccccgaac 8640 acttgtgctg gcataacaaa aagaaactga tatttcaaca gcataaaaat agatgcacaa 8700 atttgaaaca aaacaacttg taaagctatt tagtaatgaa ggagatacta gcttgtttga 8760 aagaagtatt agaaatatta ggaaaatggc gggataattt ctatttaatt gtactatact 8820 ttcaggatct tccctaagtg tccccagaac aagcagtgcc aacaatcaaa tctcaatagg 8880 aaagtcatca gttgcatcta catggggatg agttagttct aaaaaggttt tgctgtcttg 8940 cacaaataga atccttcagg tcactggatg gaaacaagaa gtaggataca aggttaccta 9000 taacattcta atcagaaatt caaactggaa atgacccatt gaaaacgaga aacaacataa 9060 tcaattagat ttccacctta acacgaatga aataagattg aataagatca caataaaaag 9120 cctcaacctc attttgctta caacaaggtc aactttattc acattgtggg tctacttcta 9180 ttccaatttt acttagcaaa agttatacct ttcttttccc aattcatgaa caatagtggt 9240 cagcttaaat aattgctgct ttcccaatct catgtcaact ctttattgtt tttaaagggt 9300 actgttgggg gtttctttct ttcatttcta tttgtttaca ctataaatgt actatcaatg 9360 gggtaaccca ccactagtat cgttacaact aatcgaagca tcacaaagga aggacaatcg 9420 tgaataagct aataggaggg cttgatttag tttgaatcgg atgtactttg gctatattaa 9480 ttaactgttg tatttttacc ctacacatac atatctgcag gaatcacaca aaattgtcaa 9540 atttacatac ttaaggattc ccaaataata caacttgcta taactcatga aataatgaag 9600 ttcttttaat actattggta ccgttatggt cagaaacttg ggcattttgg attcatgtta 9660 aaaacagaaa tatttttgtt ttaagctgtg tgaactttac ccggggtaag tgttgggttt 9720 tttgatttga attccccaga agcagatttt gttataactc gctcaatatt tgtgctacgt 9780 tgaaatggtt aagatattta gaatcagcgg gtcactttgt atcgattagt gtcatcaaag 9840 ccaaaatcta aattttgaat ttgttagtgt ttttttttgt atggggatta ggttcatttt 9900 gcattttcga aaaaaaatca aaaattttcc aaaatttcaa acttgctaac ttaagagttc 9960 agaaaaacga aattttgcca taactcaacg aatatttatg ctatattgaa attataagga 10020 tatttagaat caggagctca atctctatca tttgatgcta tctaaattga ttttaaattt 10080 ttaacgttta cccggatatt tgccagattt gtttacttag taatttcagg aaatactttt 10140 tgctataact cgctcaatat ttatgctacg ttgaaatggt taagatattt agaatcagcg 10200 ggtcattttg tatcgattag tgtcatcaaa gccaaaatct aaattttgaa tttgttagtg 10260 tttttttttt gtgtggggat tagcttcatt ttgcattttc gaaaaaaaat caaaaatttt 10320 ccaaaatttc aaacttgcta acttaagagt tcagaaaaac gaaattttgc cataactcaa 10380 cgaatattga agctatattg attctataaa gatatttaga atcaggagcc caatctctat 10440 catttgatgc cattaaaagt tatatttgaa tttcaacttt tacccggata tttgccagat 10500 ttgttgactt agaaatccca agaaatgtat tttgttataa ctcaaccaat atttatgcta 10560 cattgaaatg gtaaagatat ttggaatcag ggactcattt tccagcggct gatctcataa 10620 aaaaccaagg tcatattttt gccttatgtt atctatttaa agcctacccg gctatcgtct 10680 ttgcgaaaat ttcaattaaa atcaaggaaa acatatggtc tgtaccctac ccggcgatcg 10740 tctttgcgaa aatttgaata aaattaagga aaatgtatca tcgggacgct acccggctat 10800 cccctttgcg aaaatttcaa taaaacaggt tttctagtgg tttgcagtat attttactca 10860 acaggtctga aggaattccc catagaaagc tcttttcctt gttattatgg tatagtaaag 10920 agatgttcaa gtgtctttaa tctacacagt catacactat tattagcaga gcaggtctta 10980 aattgaaaga aatacatatt atactcattc aagagttctt ttttatcata tttaagttta 11040 tttggatatt ttcttaaagt cttagaacta aacacatact tgatatattg aagatactat 11100 aaacgctact atcaactgac acatttcaag attaatgttt gatgcacgct gataacaaaa 11160 tttgatttat atggtgtggc tttgttttag caattgggat tagatattag atcaaaatgt 11220 cagtatatct attgatggat gaatcaaata catctttaaa gaaatgaact gccaaactat 11280 aataacgcca atggataccc acgaaaataa ggagcagttt taacaactgg aatacacaca 11340 tttgtgttta tccatcttga tgccagggat ttagatttat ctatcaactg attgaatcaa 11400 agattagaag ttttgataat aattgcaact aagtcggtga ctatttgtag ggagtttcac 11460 tgttgtttag aactggttag cttatgaaat ataaattgtc attaacattt atcagaaacc 11520 ttgtaattct ctttccctta tcgccaatga attgatctta aatcatatat cttaaagaaa 11580 aagcgagttt cataatttgt gctaacaagt ctagtttcat catcatttga tagattggtc 11640 aattaattta ctcttttgaa tttcttgttt gttcttgatc attaatgatg gattccttat 11700 tctttttgtg gtagatagtt gtagatacat ggatagaatt atcataattt ataacaccaa 11760 tttaaacaaa gtgaagtctt ctaaatagat caatctaaca ttctaaacat ttctgaaatt 11820 aatttattat tagaatagag tggttttcaa gacttaatta tatataatag aatgtatgtt 11880 gtttgctaat agaaatcttt ttttggcgtc aaatttgtat tgaattatca tcaaaaattg 11940 gcaaccaact attttttttt ctttgtttgt ggtttaaatt ctacaataca tacaaataca 12000 aatgccgttt ctatagatct tataatgatt aaagaagata taataagtaa caagttgttc 12060 gttatataca atatcaatga agtagaaact gatgccaaag acagcgcttt tatgatcaat 12120 ccacaaagaa caatcaattc ttgatgcatg ttcagaatct actcaagata aatcatcaaa 12180 gaataccaac aagcataaaa gcaataactc ctttcaaaag tgaaaatact aatcaatagt 12240 catcatgaca attgtatttt ttgttgtgta gtttaattat gtaatgttgc aaaatgtgtc 12300 aattcatttg aaggagtaaa catgcagata tgatgataaa gtaattcatc gaataaactg 12360 caagatatta ttaatccatt ttcacaaata tcctaagatt tgcctatcac tttacctgaa 12420 agatttgaat attaaatttc agttacaatt tattgcatgt gccagtttca ttatcgttat 12480 ttccctagtc aatcttcccc ttcttgttaa ttacttatca agttattgta acgttagcaa 12540 ctgtggtcaa atattaaact tcctcagttg tttcgggagc gatctgtaga ttgccaaata 12600 aagaaagact tttcctattt tgaaaccctt ttttagcaac aacaacaaat tccagcagct 12660 tttgaatggt tggatgtttc agtcttaaga atgtagctgt ttatttggga tggtggtggt 12720 ggttgttaat ttccaattac ttattatgaa acaagatgga atgatgtgtt aataatttac 12780 gtcgatcatt agggcgtaga tcgtttgttt tggtacctgg ttgtggtggg gaatgttaga 12840 catttcattt agttgtggat tttttttttt tggtgttcag gcatatttta atgcgctggt 12900 gttgtaacca tcgttcctag ctagcgcgaa atctactacg aaatattggt ttttgctcgc 12960 cccattgctg ttcttccgta cgccttacgt gtccactgac tacgatacca ttgcgcgaaa 13020 aacaacaaca aaaaaaagat cttcgttaaa ttcgccaatc acataaaagc ataaacaaca 13080 ggataaacct aaattttgga gtaaaacata aacagcaaga gaaatcaaat tcagttcaag 13140 aagtattatt atcactaaca gtcaagattt attcacaatg ttgtacttta tcttcattag 13200 gatatgttat agagatgatg gattaaattg attgctttca aaataatttt tcagccaatg 13260 acaatcgcgg gattggtaat ttcaattcaa tataatgccg atgtgtttca cactaaaatt 13320 ttcatttaat tcttcacata ataaaatttg ttactttagt gtttaattta tcaaaaacaa 13380 ctggtatgtt tagtgataca ctatatggca aaactaaaaa gggttaaact aaaaagggtt 13440 aaactacaaa atatttacat ctatgtcaaa gttgcaaata aaaacaattg acaatctttg 13500 ttatgattct tataattccg ggaataacac tagtaattta acgtgtctac ccgtagtatt 13560 ttattattat catttttttt ttccaattat tgttcccatg atttttacca cctgatgaga 13620 tactataaat ggaagagtaa atcacttgtc aaattcacaa ttattaaaat aatgatcttt 13680 tatttttatt tcaattgaaa aaataaatta aacacacaca ttaactttaa aactattggt 13740 tgttgttgct gttaattagt tgcaaataaa atcatcacct tcacaagaca actaaaattg 13800 acaaattgtt gaacaaaatt acactactaa tatattgttc aatttcaaat attcacactc 13860 taattggctc attactcaat tcggcaaact aatcccggtt ggacaaaaga agagagaaga 13920 gagaaaaaaa aaagaaacgt gcaaaactta ctattactat tagtaccaac caaccaaaaa 13980 aaatttcaca ctacaaaaac agaaaagaat ttaaattgga aagaaatttt cttttttttt 14040 aatctatttt catttaatcc aaaacttcaa atataatctc ataagatttt ccaatttcaa 14100 tttcaatttt aattttcatt taaaagtttt ccttttgctt tttgctttct gcttttcatt 14160 taatctttat tgatttacca aatatacttg attaaaaagt ttctattatt tcctcccgtc 14220 catttctata tagtcaacaa tttatttaca tacaaaaatg cctcatcata ttatgtcaat 14280 taatgattct aatcatgttc aaatcggtgg tagaaaatca aaattagcag ttgttcaatc 14340 agaaattgtc aagaaggtta ttgaagacac tttccccaac ttgtcatgtt caatattagc 14400 attatcaacc ttgggtgata aagtacaaac ccaaccatta tatacttttg gtggtaaatc 14460 attgtggaca aaagaattgg aaattttatt actagatagt gttgatgaat ttcctaaatt 14520 agatcttatt gttcattcat taaaagacat gccaactaat ttacctgaag aatttgaatt 14580 gggatgtatt ttccaaagag aagaccctag agatgctatt gtcatgaaac aaggatcatc 14640 atataaactg ttgaaagatt tgccagcagg tgctattgtt ggtacttcat caattagaag 14700 atcatcacaa ttaattaaaa actatcctca tttaagattt gagctggtta gaggtaatat 14760 tcaaaccaga ttaaacaaat tggaccaacc aaataatgaa tattgttgtc ttatattagc 14820 cagtgctggt ttaatcagat taggtttggg tcatagaata acatcttatt tggatgatat 14880 gtattatgct gttggtcaag gtgctttggg tatagaaata aggaaaggtg atgataatat 14940 caaatcaata ttaaagaaaa ttgaagatcc tattgctact atttgttgtc ttgctgaaag 15000 atcattaatg agataccttg aaggaggttg ttcggttcca ttaggggttc atagtgatta 15060 caatgaaagc aaacaagaat tgacattaaa ggggataata gttagtcctg atggaactgt 15120 ttctattgaa gacgaagtaa ttaaaagaat tacgtgtgat gaagattgtg aacaagttgg 15180 aattgaatta ggtgacaaat taaaagcaaa aggtgccaaa gaaatattgg ataagattga 15240 tatgacaaga aacattaatg ccagacctac tgaagtgtga aattaaagaa tttaccaatg 15300 gtgatgacaa tatgtttgat acattttgat ctacatcatt gaaaaattga gggttttttt 15360 aatttattta tatatttatg gttttaattg ttatcgtctt tcattcaatt atggtagttt 15420 atttgattcc aaattattca gtttcatatg gggtaaggta ttcatttatt catctttttt 15480 ttgccttata ttttgttttt tttggttcat ttattaattc gttttattta ttgttccatt 15540 ttttgcatat tatgttatgt tatattaatt taagattgga ttaaaaagaa gaacttgtct 15600 gtatatattc atcaagaaaa gtttattgtt attacacata catatttcat tttagacatt 15660 gagtttggtt ttttttagtt attttgtttt tttcttttat atatattagt ttatcgtttt 15720 tagtaagtta atgaatacat ttgatagaat tagattgatt ttatattgag taagaaatga 15780 taaagtaaag aatagacttt ggtgtagacg atgagttgat tatagtgggg caatacacaa 15840 caatcttcat tcataagtat agcattttga tttccttata acctccccca ctttcaacaa 15900 agcccaattc tagaatagaa gaaatattcc tctttaatat ggtttatctt agaaaactta 15960 atactgacga caggttagaa aattatttaa ctatttgttg gattgtaatg ggagagatga 16020 tgcacccgtg atctattctt tttgttttga attcgcttat gcataattaa gtatggtttt 16080 tttattgttg ttagaagtta tcaatgagtt cttaattgtt cgaacttgat acaataatta 16140 acaatcaaca gactaaaaac gaatggctat agtttgcttt atacagagtt ctgtaggcta 16200 aagctaaagt catactaact tatcgagggc tatattatat taagatgccc cgggctcaac 16260 acacactcta caaagaccct ctagacaccc accccctttt tccatttttc attgccactt 16320 tccaagatta acaagaaatt tgcaatttct cttgacatca atataaccac cactattagc 16380 accaccacca caaagggtcg acatatgaaa atgctaagaa aaaaaaaatc aaaaaaaatc 16440 aaaaatattc aaaatcaaaa tcaaagaact gacaaaaccc tcataacatg aaaccgcata 16500 gtaaaataat tattatcaat tttcttccaa tgaaaatcct aagtggattt ttttctttag 16560 tttattctgt aagaatatgt acttatgtgt atgatgggtt ggaataaact gtttttctat 16620 ttccatttcc gcttaaaaag aaaagaaaag aaaaatggaa tttttatttt aatttgaatt 16680 atctaagaaa tgggagtttg gggattggac catttaattt cttggcatta gctatttctt 16740 ttctttttta ctaaagattt acttgtcgag gttagaaatg gaaggaaggg gcgggttgaa 16800 gttgagattg atattgaaac tcatccagat tcagattcag tgtctgatat ttagaaatga 16860 ttaaaattga ttttaactaa aagcgttcaa ttcttatttg aggtctaatt tgtggggtaa 16920 aagaagaaat tcatgataac aaaaaaaatt acgaactccg ataggtttat cattaccaac 16980 tacttactac tttccaccca cccacaactt cctaattatg caataaatac ttgcgcccca 17040 cttgagccac tccctgtttc ttcctctcac atatctaact aacaaaataa tcaattagat 17100 ttgccaaaga aatttaagca agactcttga gacaagaaaa aaataaagca aaaaagaaca 17160 atgaacaaat gttggaagct tacgaatgga agaataatga attctttatt attattctct 17220 acttcgggca tggctcttcc actgttcgct tcttttctcc ccccacaaaa gctattcaat 17280 aagtactggt agaacaaata ccacttgaac atctttacct tctaacttga aaactgtggt 17340 tcttgtttgg ctagaagtac aaactttgtt cttactactc tattattatc attgtcttcg 17400 gacttttcct caacattatc gttctcaccc atcatcaatg ggaaattctc gtataaaaca 17460 atttactgtc ggacgacaat gcaattttca ctgtctgatt cccgtgatct tgtagaattg 17520 ccattctatt ttttttttct tgaccttttt tgatagttca ttctaaagtc cgaaaataaa 17580 gtgggtcaag atcttttgtt tctaatgcta aaccacttac ttacctacct agctacacac 17640 caccacttct tagaatagtt attcaaccaa ccaacttaac tcatattcgc gtataattaa 17700 ccttgtctac acgtacacaa aaaccagact agtaataata ataatactga cccaattcta 17760 gtggtttatt atttacccaa caactaacga tatcgaccac caccaccacc accaccacaa 17820 taataataat attaattact aaatatcatg catgaaaccg tctttaaaaa tattagtaaa 17880 aacacaccca cacacactca tccacccacc cacaacggag tttctcaact tttcccacaa 17940 ctataaatat tcacccaaat ttcttttcat ttttgcttgt ttctcatatc gaaatttttt 18000 ttagtcctta accaacaaga ctttttactt ctaccccctt cttctttttg attcattaac 18060 ttttttacat ttacatatca attgatttga tttgattttg attaatattc aaaaaagaag 18120 aataatcata agcaaaacaa tatttattca attcatatat aagatttatt gtttattgtt 18180 tcccgctacc aattttatca aatacttaag agattgatat aaaattacca cgcggtcaaa 18240 aactttatcc ctccccccac caccattgtt aataaatttc ttgagttgct accaccccac 18300 cacacacaca tacgctccca ctcccaattg atacgaaaaa gacgtgcgct tccccactcg 18360 acatttccac ctttttaaac ttattcccta attaaagaaa aatttaacat ataaaacgag 18420 acaaaaataa tgccggaatc tactcaacaa tctcatcttt ctttggacca tgagaagatg 18480 caacaacctc ctaaagggtt cactgaacgt tctaaaacaa aaccaaactt agctgatttt 18540 gaaacttatc aaaaattata taaacaatca attgaaaacc ccaatgaatt tttcactcaa 18600 caagccaaag aaaatttgga ttggtttaaa ccatttgatt tagctagatt ccctgttgat 18660 cctaaagatg attacaaaaa tggtgatttg ccagcttggt tcatcaatgg acaattgaat 18720 gcttgttata atgctgttga tagatgggcc attaaaaacc ctgataaacc agcaattatt 18780 tatgaaggtg atgaacctga ccaaggaaga attatcactt atggagaatt attaaaacaa 18840 gttagtaaat tagctcaagc cttaactaaa ttgggggtta aaaagggtga ttcagttgct 18900 gtttatttac caatgattcc tgaagccatt gtcactttat tagccattgt tagaattggt 18960 gctatgcatt cagttgtttt tgctgggttt tcttctgctt cattaagaga tagaattttg 19020 gatgctgatt caagaattgt tattactgct gatgaatcta aaagaggtgg taaaaccatt 19080 gaaaccaaaa aaattgttga tgatgccttg aaagaatgtc caaaagttag aaatgtcatt 19140 gttttcaaaa gaactggtaa ttctcatgtc ccattttctc ctggtagaga tttgtggtgg 19200 cacgatgaaa tggctaaata tggtccatac ttcccaccag ttcctgtcaa ttctgaagac 19260 ccattgttct tgttgtatac ttctggttct actggtaaac caaagggggt tcaacacaac 19320 actgctggtt atttgttagg agcagtttta accaccaaat acacttttga tgttcatgaa 19380 gatgatattt tgtttactgc tggtgacatt ggttggatca caggtcatac ttattgtgtt 19440 tatggtccat tgttagctgg tgccacatca gtggtttttg aaggtacccc agcttatcca 19500 aattattcca gatattggga aattgttgat aaatataaag ttaatcaatt ttatgttgct 19560 ccaactgctt taagattatt gaaaagagct ggtaccaaat atgttgaaaa atacgattta 19620 tcatctttaa gagtcttggg ttccgttggt gaaccaattg ctgctgaagt ttggcattgg 19680 tataatgata acattggtag gggtcaagct catattgttg atacttattg gcaaactgaa 19740 tcaggatctc atttgttgac tccgttagct ggtatcacac caactaaacc aggttcagct 19800 tcattaccat tctttggagt tgatccaaag attttagacc caaccactgg tgaagaatta 19860 cctgataatg atgttgaagg ggttcttgcc attaaatcag cttggccatc aattactaga 19920 ggtatttaca atgattacaa tagatttatt gatacttatt tggcaccata cgccaattat 19980 tatttctccg gtgatggtgc tgctagagat agagatggtt tttactggat tttgggtaga 20040 gttgatgatg ttgttaatgt ttctggtcac agattatcaa ctgctgaaat tgaagctgcc 20100 ttgattgaac atccaattgt cggtgaatct gccgttgttg gttatgccga tgaattgact 20160 ggtcaagccg ttgctgcata tgtttcgtta aagaaggata aagctgttgg tgaagatgta 20220 gaaaacatta aaaaggaaat gattttaact gttagaaaag aaattggacc atttgctgct 20280 ccgaaaatga ttttattagt tgatgattta cctaaaacta gatctggtaa gatcatgaga 20340 agaattttaa gaaaagtatt ggcaggtgaa gaagatcaat tgggtgatat ttctacttta 20400 tctaatccag gtgttgttca acaaatcatt gatgttgttc atcatgcaaa gaaataaagg 20460 aaagaaaaca acttttagat ttgtagaatg aatacaaatt tgtctgtttt tatttgagtt 20520 aattttcatg tttatttgct tttaaatctt ttttatatct gccttggcca ctccaaatga 20580 ttaattttaa cttttgtatt tttaattact tatttagtta gtcaatttga tcaaatccga 20640 ttgctagttt tatttattta gttaaatata tttattattc ctattgatac tgttacgcaa 20700 tcctaattta tttgtacttt tacaaggcgt aagttttatc atattgaaat atagtttcaa 20760 ataaagcttc aggatcaggt tttggtgcta tcacatgtgg tgataaatca aaatctttta 20820 aataatctct cgttgtagga ccaatagaag caattttcca atttttttga tttgaattac 20880 catctcgatc aattaaataa ttaacaattt ctttcgttcc ttgaggactg aaaaatacta 20940 tccaaacatc atcattatct ttatctttat ctaaaccatg tatcactttt ttgaaattat 21000 caataatatc taatcgatca ccagtttgat aaagtataaa ttcttggaaa ttattatatc 21060 cactatcaat taatttccta ggtataatat cttttctaat cacaccagta aagaaaacca 21120 tggggatatt ttctcttcct atagtatctt gtttaattaa atcggccaat ttcgatccat 21180 tgcctgcttc atcacctcca cgaacatctt taaaccctac agattttaat attttataag 21240 ttgctggccc cactgtatat ccgatttttt gatatatccg ttgtcgtata tcatgattta 21300 attcttcaat acattcttta aacatttcaa cggctcgttg tgaagtgatt ataaaaatcg 21360 ggatattatt caaaaattca tcactgatta aaaatgataa tgtttgagat ttatctttat 21420 gacgatgagt taataatgga acaaaatttg gtttatattt attggaattg gaaaatttta 21480 tatcatatgg atcacaaggt atactagcat tctttagtag tataacatta gtcataataa 21540 acaatacagg tattaacttc ttgttaaagt ctttcgaggg aaaagtatat tatttgatgg 21600 tttggtaatc cttgaaaagt gattggagga aaaaaaaaaa ttctggcatc acgtctcgtc 21660 acggaagtcg tgttaaactg acaagtgtgg ctagttcagt ccactccaac cagtggctca 21720 taaaaccaaa tctgcttcca ccctcattca ttgattgact atctaacttc ctctaagagt 21780 acacaagctt ttcaagatac acagctaaca cagcattata ttattacatc atatgctagg 21840 aaatgacagt taaggagaaa tagaaaacat aaatttggcc aggccgtgcg ctaaatctag 21900 ttcattgtca gtttcataag cttttaatct ctcacgatag actacaatta tctttacaat 21960 caaacttaac atgaaaattt aacaagctgc acaactaatt gttgactaac tatcagcaaa 22020 taagtacatg aaacaaagcc ctaatcaaat aggacaatgg tattttttca ttcaaatatg 22080 caaattgttc caggtttgat gcaattacgg tactactgcc caggttttta tttttagatt 22140 ctattgtcat agacaaaatg taacaaggca acgataaaca gaaaacaatg aacgtcttgc 22200 ttagttatcc aaattttatg ggacaaaacc gatctttaat gtggcaggtg catcatactt 22260 ttatcaacaa tcaggttctt gatattcatt gtgtctgatt ctccttctcc agtgtttgtc 22320 aatccaacca attcttaaaa tcacaataga acatatccat ttagttcaaa catttcacac 22380 tatatttttc taaaaattaa ttatagtact gttttgggta caaaatcaaa aactgctaaa 22440 caatagtatg acgaaagaaa gtcaagaaac taacaatatt agattaatag tgtggtatcc 22500 ccctacaaat caaactcaag tactaccaac aagtattttt cacaatttta gcattgtttc 22560 tgctatacaa tctattattt gagttgtttg tacccagttc ttgttctctc ccccacacat 22620 acctccttac aattgtgatc agtgtaccta aacactacta gcacacaaag tttttgttta 22680 tgtggatgct gaaacagaca gccgtcaagg aaatgatata aaaggagaag gaaatcttga 22740 tttaacttag aatttcattt tatcaactat cactaccact accattaccg ataataaata 22800 tgaaattctt tactgctgct actactgctt tattattatc tgctcaagct ttagctgaat 22860 taacttccta taaattatat gccaaatctg aaaatactga agttgatggt aaaggtgttt 22920 caattttaca tgaaggtgca ggtatctatt ttgtcttttt aggtactgaa agcattgatg 22980 ttacttatga tgatgttgaa aagcttttat atgtcccagt tagttctgat attcaattca 23040 attttggtac taatgctgat attgtccaat tttcagtaac ccctccagtt tcggttgaaa 23100 ttgctgaaga tggatcggtc aattttgaag gatctgatga ccttttcgcc gcgcaataca 23160 ttaatgatcc atataactat tccaaggatt catatgcagt tatccttaga ggtaaaccac 23220 atgccattcc aatcaaactt gttgctaaga agaattagac actcggatgg ttttccagat 23280 caaacattta tagcatacat agctagaatc aaaatatgaa tgaagaaaaa attgatacaa 23340 aaagatgtag tggttataca ataatattac ccttgttatg cttaccttga gttgcaatat 23400 tatttttaat gatatcaaaa aaagtagcta tagagatatc aaaattttgg ctaattgcaa 23460 tggctgcaaa aaaataaaac cacacttgcc gaaagtgtca tattcagtac tttttccaat 23520 tatagccaag cactgaaagt tagaaatcta tcatgttaaa atcaattaaa cgttctgatt 23580 catatttact tgaaagttca tctagcaaca attcaacttc aaacattata acaacttcta 23640 caaacaatac tcaaaattca ttattaaaaa gaaccactaa acccaatgtt tcttctacta 23700 gggctccaag tttcacgttt tctcgacttt tgtcagaaga tacttttaat tataacacta 23760 atagtaacag caataatact aatattcata accctaataa taataatagc aagtattcca 23820 caattcatgg catctcttct tcaagcagaa gaaataattt tttaaaagta tgttcttggc 23880 catttaccaa aattgaaagt ttccatgata gtataacgaa aaatgataat gacaatgatg 23940 ttgataatga taatattgtt gaatttgctg atgatcaatc aacacttggt aatgatgatg 24000 gtaataccaa gcatttaacc attgctgatt atagtaatat taaaagaaaa aatttcggtg 24060 gattaatcag tgacagtaat ggtagtggca acggaatcca tgggtataat tatacgttag 24120 gtggccctaa taatggtagt agtggtcccc tcactgggat caatccaagt ttagaaaaca 24180 ttaatcatgt tgctaatgaa aaattccata aagtgtttaa tcgagtgaaa cgaccaccag 24240 ttgaacaaaa caataaaagg agatgtgtgt tattatccaa tctcaatgag tcaatgggat 24300 tgaacagtgt tttacaacaa gtatgtggag gtccattgga aaagttgacg gtattatcaa 24360 atggcaaaat tgaattattt ttcatattcc ctgaacatgc aaaacaattt tatacatatg 24420 gtaaagccac ggggttatta atggtaaatg gagtgaaatt aaaagttgaa tggttgaatg 24480 atgagaataa tttagttaat tctacattat caagttcatt aatgagtgat attttacata 24540 atggatgtag aagatgtttg attatatcta aaaatattcc tggtaaaaga attagaaatg 24600 gtgataaaat gttttatcca gaacccgata ttcattattc aacaaactta aattttgaag 24660 aaattaaaaa tgatttcaat aaatttggta aagttcttga tattggttct gtcattagta 24720 gaaagttatg ctttagtgta ttctattatg acattagatg tgcgatatta gcaaaacaag 24780 aattggattt gattggaagt gaattaaaca aaaaatataa agattggtct atttggtatg 24840 gtaaagatat cactgatcgt gcttgttttg tcttatgata atcaagggta tttaaacagt 24900 tgttataaca accaaccaac caaccaaaag acaatacata tctctctttc tcttaggtac 24960 tacgtgtata cttcttcttg ttggtgtaat tatttttttt ttttgcagtt acatttcctg 25020 atttggacaa attgtcaaca ctgtaaacaa atatcaaatt cctcatagaa attttttttt 25080 tttttttgta acgatcaaat tcttcaaata tgcaataaac cacaaacaag agaccaatta 25140 ataagaccgt ttacccttgt attcttttcc ctgttgttct tttattgctt ttgttccatc 25200 aatttttcct ttcgtttatc attatcatct acactagata caaacacgta ttgctaatgt 25260 cccataaaac accaacaaga gcaagatctt gctatgctaa tagttctact acatcaatga 25320 attcaactcc ttctagaaac tcattcagac caccatcaag attatcatta attcctagat 25380 catcttcacc tatccaacca cctagatctc gtccaagttc agcaatgtca attagtcgac 25440 catcaacacc atcaatgaaa agtcaagagc cgtatactgg cgccattacc gtgtcaatta 25500 gaccaaaccc taatacaatc gataacaaaa attggagtat cgatgaattt gataactcga 25560 taataaatac cactgatggt acaagatttg tgtttgataa tgttttccct atggatagac 25620 aattgagtaa tatccaagta tataacaaat catgttataa tgttgtcaat aagtttcttg 25680 aagaaggata taatggcact atatttgcct atgggatgac ggggtcaggt aaaacatttt 25740 ctatgaaagg gtgtgaaaat gatcctgggt ttgttgaatt ggcaatcaat gatattttcc 25800 aaaaaattaa tgataatacc actaccaaaa aatataaaat ggatatttcg tatcttgaga 25860 tctataatga aaagattata gatttattat ctggatcacc atcatcccaa acaacttctc 25920 agagtaacca agatttgaaa attagagacg atgtggattt tggtaccaaa gtagttgggt 25980 taaccagtgc taacattagt tcaaaaccac aattattaca attgattaaa tatggagata 26040 ccaatagaaa aaccagtgcc actgatttca atgctagatc gtcgcgatct cattcaattt 26100 tacaaataag attacaagtg attgatttat tgactgaaac agagttgaaa tcaacgttat 26160 ccttatgcga tttagcaggg ctggaaagag cagcaactag tttggaaaga cgaaaagaag 26220 gttcatttat taacaaatca ttattggctt tatctaatgt catcaataaa ctttcaagtt 26280 cagctctaga acatattccc tatcgagact caaaattgac aagattatta caaccggcat 26340 taagcgggtc ttcattggtt ctgattcttt gtaccatcca tatgggagga aatcaacaga 26400 attctcaaca atgtgttgcc gagacatata aaactttaag atttgctgca agagctaaag 26460 atattgttat aaatgttgaa aagaacatga gtcataagct tgatggtggt gattcaagta 26520 agatgattca agagttgaat gagattatca gtaaacagcg acaagaaatt ataaaactac 26580 aatcaaatac gggtgtatca tcgaaagaat ttgagaattc aaggattgtt caattggaat 26640 cagaaaatag agtattgata gagaaattgg atcatttaac tagactaaca gatctacaaa 26700 aaacagaaac ggcaataatc aaaaatgata tattgaatga tattttatct tctggtttag 26760 acaatctgca aattctcatg acaaatattg aagatttcta taaaaaaatg acttatgaag 26820 ccaatgaata caaatcatat atttgtcgtt tagaaacaca attaagatta gaatcaataa 26880 atagtaccca acaacagcaa tcatcatcac caacatccag tataccaatg acaaacacca 26940 ctaatgattc atctgaatta atggatgctt tgaaagaaca agaagaagaa attcttatgt 27000 taaaagaaca attaaaagac aaagatcaaa taataaagag tttatctcaa acgacaagat 27060 tacgtcgatt agttggtaat aatagcaata gcatcgctaa tagtcataac acatataata 27120 ccttggataa tgatttcaaa cgacacacaa caatagtcaa ttttgataaa gagaattatg 27180 aacccgaatt acgtgatttc aagttaagtc caaagaaacc aaaatcaaat tgtgatattc 27240 tagaaagttt ttgaatgtga taaaaagggc taaggttttc tagttttttc tttctctgat 27300 tatatatact catatattct taattaataa tactgtttct tcttttttaa aagaattcaa 27360 cacttgttaa aacatgtaga tatcgttaat tgaatttgga actggctgaa tcaaattgat 27420 gttgattcat tttgggtttt gtgtcagaag ataacgctct ttatcaattt cctgcatata 27480 agttgtttct tgtcctattc cgcttttcat tccagccggc ctcgcattgc cctccttccg 27540 cttcccatcc tccgtctaat gcaaattctt aataacaaat tcagccttgt cttcatttta 27600 atactttcat cctactccat attcactaac tctttaacga ttaaaaccat tttgaactaa 27660 tatattaact gatctacctt tgaagtatat tttcattcat tcattcattc tttttatttg 27720 gaatcacatc tttgaattaa attggttttt aagaagtgaa ttttcaagcg atcccaacaa 27780 cactcaccac ccaccaccca ccaccctaga tttaacaact tagttatgtt caagaaacta 27840 cgatcaaact ctactgtatc acataataga agaacatcca ctagtgattc tcaacaacaa 27900 ctggtacggg gtaatcatga attgcgaaga cacagccaac caaacccaat tatcaattat 27960 gaagtattac attctacatc tacagcaaat gggaggaatc acattcgtca aaatgagtct 28020 gaatcagtta taattgatga atctactgat caagaaatgt caccattaac aacgactcaa 28080 agtaatcaat cgacagcatt atctgaggca aatacattgt ttattgatag acatcaacga 28140 ctagagttac aagataatta tttagataat ttcacaatgt acttaccatt tgtgattaga 28200 caaatgcgat taattgagga aagacgatat ctagaatcac aagagtatcg taatgaaaat 28260 gaacaaacta gcgacaataa tgatccatta caacaacaac aacaacaaca acaacaacaa 28320 caaacttcgc gtcatgttgt aatacccgat attacaggtg atgatttaga tgatatttct 28380 accatatttg atgaagctca tgtcccatta gaaacttttg ccatgaatca ttataaaatt 28440 cttgaaaaac aattgtcatc atttgatatt aaacgactgt ttataattgt tgctggtatg 28500 ttaaaacata atacttatat attccctagt gctgaatcat ttgaattatt taaacaacta 28560 cgatcgagca ttaagaaaca tcgcaagaat ctgatcatgg tatatgacaa ccaaggaact 28620 attaaacgag catcattgac atcatcaaca acaaatatca aacgagaaga tattaaccaa 28680 gaaagtgaag gaataataat tgatgataga ccccatatta ttccattaga tcaaaaacta 28740 aaaggattag gattaccatt gtttaaaatt caaaccccat atttatcttc atttcggaaa 28800 aatactccat gtataatttt caaaagatat aaagaagttc ctcaacctcc accagcacca 28860 ccacctgcgt caccagcatc atcgtcgctg acaccgtcat tattattagc atcatcatca 28920 tcgactctgt cattggcatc atcgttacca ggcaaaataa aagtgaaaaa atccccttca 28980 aaatcatctg atgaatatac ttcaagtaaa gatgattttg aatttgaaac atataatttt 29040 tgttaagtat attccaaata ttttcaatca tatcgaagat ttatatttga attcacacca 29100 ttggatcaac caagctttaa agtcattatg tttcaaagta atttacgacc atttgctgat 29160 tttttatata aaaagactcg ttttagagta attggaccag caatgttact gggtgttata 29220 caaaattata atcctcatat gagattatta gtaatagatg atgataaacc ttcattagtc 29280 gataatataa tcaataaaaa accccatagt ggctcaaata cctccattgc cacagtggcc 29340 accaactcaa ttactggtgc cgccgctgct gctgctggag gattatttca taaacgtaaa 29400 tcaaacgata aaaaatccaa aacatatgtt gaattcaatt atgatgatcc aaccacattt 29460 attaatccaa tacctaataa tacatttgcc gacgaagaca acaacgctaa tatcggtcaa 29520 gcaattaata cttcactgta tataagcaat gatttaccac catttggttg ttttaaagat 29580 tcaatgttat atcgaactaa ttctagttta ttaccgaaaa aatatactga agaaggtaaa 29640 attcaaatgt atcaagataa actgttttta attgataaag atgaaaatag caccctttca 29700 attgatattg attctatggt tcttgtttgt atcatggcta ctttaagaga tatatcgatt 29760 aaaaatgctg gtagaacaaa tactcaaagg acatttggta ttggattagg taatagaata 29820 gggtatggat tagaaccatc tcatgtaggg ataattggtt tatagaatga aatacaccaa 29880 aaatgttctt tttttgctga attgtatatt ttgttactat ttagatgtat tcagatacct 29940 tatcttctta tatcaaagct tgattaattg atacatcaat tgatctcatg ccaatttaca 30000 ataaaagtga ttttggaaaa gaaaaagaaa ttgaggtaga aataaagtat ataataaaaa 30060 gaaaaaggat agaaagaact tgctcattaa taatctaata acgttctggg gatcttgatc 30120 tatctcttct aggaggagat cttgatggag atctactgta tcttctttct tcaactcttg 30180 gttctctacc ttcatcacgt tcatatcctc ctctatcttc ttcacgatca taacctcctc 30240 taccttcctc acgatcacgg tcataaccac ctcttcctcc tccataacca cctctaccac 30300 catcgcggta tcctccatca cggtatccac cgtcacggta acctcctcct cttcctccat 30360 cacggtagcc accatagcca ccacctcttc ccccatcacg gtaacctcca taaccgcctc 30420 ttccaccatc acgatatcca cctcttcccc cgtcacggta tccaccgtaa ccaccacctc 30480 ttcctcctcc ataaccacct ctaccaccgt aaccaccgtc gcgataacca cctcttcctc 30540 catagccacc atcacggtag cctcctcttc caccgtaacc tccatcacga taacctcctc 30600 ttggaccaga aaattgttgt ctcacacggt atgggtcgga tctggcaact tgaacaacca 30660 atccgtcttt gattgaatat ggcaaagttt taccatccaa ttccaaagca cgttcacaac 30720 tttctgcatc cttatattca acgaatgcat atttttcacc atcgtcggat cttggtggag 30780 gaatatctaa tctaactaat tctccgtatc tataataata ataatttgat aattgttgtt 30840 agtctcgatg aaaactgatg aaaaaatgat actaaaaaat atttttgttg ttttattcta 30900 tgtttgtttt aaaatttggg gaggggggtg ataaaaattt agaatggtac aaatgggaag 30960 gatatataga aatgaaataa ttgaaaaaaa ataaagttaa gaatggagga taattttaat 31020 tagatgtgat aagatatagt gatggatata attacggaga agggtgaata tgactaaatc 31080 aattcagtga ttagattaaa atattcagga aggaaagaag gaagaaggga gtgaatggaa 31140 aaggaaaagg gaaggtaaag gagaaacaaa ggaaggaaaa tggatgatct gataggtgtt 31200 caatatgtct gaaaatcaat cggattcaaa aaaaaagaat agtgaatgaa gaaatgacgg 31260 tacattcaat ggatcacttg tcaaaaatga attgagtcaa acttcacgtc tgttgacttg 31320 aactcataat caaatgaaac cggatagcag ctagttgtga attgtcttgt taagaaacat 31380 tggcaaaaat aggctgtgga tgaataggat tgtaataata tcaatataaa tgaaataaca 31440 tagatcatta tctaataaac catggaatca ataaatccta tagtttgatg ttaatttaga 31500 agaaatgaag aaagagtctg ttaagagtaa aaatccccaa ttattgaatc cataaatgat 31560 agaattatgg aaacgaaaac tccatagcaa aaaacaaaaa aaaaaaaaac aatcaagata 31620 ccttgaagtt atcataatca gttatacata cttttcaaaa tctggagcta aatcagcagc 31680 tttggattct cttgaaaacc cagtgacata taatgtattc tttggcattg taaatgattc 31740 aaagtgataa agaaaaacct aacttttgtt gttgagtttt tttttctttt ttcaggttta 31800 aaatttcgtg atcaaatttt taaatttcat tttggtcaac atacactacc aacgactgtg 31860 ttgtaagact aagtactttt aaatgaacag ttgacagtat tgaagtggta ctcttaattt 31920 agcttattgt ttaagtaaag tagtggatcg ggttggtttt tagaaactat taatgggtgc 31980 tcgatagact actaccaaat aaactttact agctttgtca ataataagaa acagtacaag 32040 tcaaattatc attgcaaagt atgggttatt aaatgattga taacatcagc aacaggaatg 32100 aatgaaagta ggaactctct tgaaacacaa gcaagttact aaaaaagtag atgatcacta 32160 cagatccata attaaaccta taaggttata ttgaacaaat cagatgaaaa atgaaagtaa 32220 caactccaac caacgaagaa ctaaaatgat tgtgaaacta aaagctaact ctgatttact 32280 ccactttttt tttggattca ggttttctga tttagtaaat gaattgtgtt ttttagtatt 32340 ctaatttaga aaatcatgtt caggaaagct taattgtgat tgtagtagta gtaggactat 32400 attcaattct cagttgattc ttcgcttcac ccctagagta taatttgtag ctttaatacc 32460 cttccattaa tccttaaagt ggcaagaaag gggctgacaa taattatccc tgcggttgat 32520 aagtattttg taaattgcta catacatatg catgttagta gtgataccct tctactatga 32580 tacatcacta agactaatag tttaattatt aaaaaaaaga cacaagcgaa tacgtgtctt 32640 actctcactg gccagctata tccacaattg aattgttggg atcttgtgac accaaagctt 32700 ataagcttct aagcttcaac cttatacaat atcaagatcc gggatcttga tctaagcttt 32760 tatattggaa aacagttgat ttcatttact acatacaggt ctacacacac acaccagcac 32820 gcctgattat gcaaaataca aataaattaa tttcaattaa ttaatgatca acagcaacaa 32880 caacaattgt tataatattt gataaggact caatatttag tagttcgtga ataggggtaa 32940 aatgtatgga gtagtgtaaa tctgaacaat tatggtaatc gtgtatcttt cctaaaacgg 33000 ctttaatagg aaaaaaaaaa aaaaggacca acaaaaaaaa ttttttaaaa tccaacaaaa 33060 aataaataat aatcatttgt acacgttatt gaacatatgg acacgcccta cacacactta 33120 ttacacacaa ttctcagaca acccactacc acccgcctac tcaaattttt gcttcgtcat 33180 acttcaatac taaaaaaatt tacaaaaact atcaacaagt tacaacaaca accgcctcca 33240 ccactttcca ctttttcatc aacgtttcta tatacttccc ttttgttcac taagaactac 33300 taatcacaac gtttctataa atcttttatt ttgttgtttt gttttgtttt ttgaaaggaa 33360 actatagcgc ttagtacccc taatctacac aatcatgaca gatccattaa cattcttgga 33420 tgagtttaat gaattctttt atttcccaga agataatgat acttttgcac caaatgaaat 33480 tgggaaattg aaatttggat caaagataaa tgcaacacca aaatctattg aagtgcctag 33540 ttcttatttg gatttttcac ctgaaacaat gaataattta ccatatagat tgagtatatc 33600 tggtttacca tctttttcta gagtagaaac tcaaattaaa atgaatttaa caataaatgc 33660 tcctttcact aatcattatg ttcatataac ccctgatctt atatcaaaaa agaaattatg 33720 tttagaagaa ccatattcaa atcttgatga taatattaaa aaacatattt tggaatttga 33780 cgcttatatt cttactcaaa gtaacaagtc ttgtgctgtt tgtccaagat gtattaaacg 33840 agaacagaaa agagcatcac gtagtaaagc tggtgaagag aaatctgccg tttgggattg 33900 tgatgttgaa aggaaagcaa tcattataaa taataaagaa atcattgctt tccaatcggg 33960 tgttttggaa ttatctgcaa gaatcatatg ttattgtcga caccataaag aactggaagg 34020 attcaaactt ttaatagtac ttaaaaacca tttagggcaa gttgttgcta aacaaatatc 34080 ttcccctatt atgattatgg acagaaagaa aaatttgaag gattcggcac ctagttcatc 34140 ggcaaatttg gttgaattgg ataagaagaa attgtctatt tctgattctg ataatgaaaa 34200 attaatgacc aaccagtttg ttcaactatc accaaattca ttggatgaat cggcatctga 34260 agctttagcc actactgatt atgaaactag aggagtgaaa cgtaagaagt tgtctgttga 34320 tgattctttc aacaccacat ccaacccaat gtacaatggg tttagtggtt attctccaat 34380 gagtaatagt gatacaaata catcggctat aagtcaaagt ttctcgggtc caacaatctc 34440 aaagccatct ctggctcaat tttctattgg attttcacca attagtcaac cacaatttcc 34500 atcacaattc caatcacaaa cacaattgct acaacaacaa caacaacagc agcagcagca 34560 gcagcaacag caacaacagc aaactgtacc atcaattcaa aaaatcatac cagctcaagg 34620 tctgattcga ggtggtattg aagtcacaat tttgggtttc aatttccgtc ctggtttgct 34680 gatcaagttt ggtgcaaatc aagcattggc tactcattgt tggtcagaaa ctactattgt 34740 tacgtattta ccacctgcag cacaaccagg tcaagtcttg gtcacgtttg aaaatcaaga 34800 taatgataat gtaggaggac cacaacaaca acaagtgttt acttatactg atgatactga 34860 tcgacaattg attgaattgg ctttacagat tgttggattg aaaatgaatg ggaaattaga 34920 ggatgctaag aatattgcta aaagaattgt tggtactgat aataataata ataataataa 34980 taatagcagt aatattaata ctaataccag tactaacagt aatagtccag cagataatga 35040 gaatgacaat aataatacca ataataatac tactgctggt gctgctggtg ctgctgctcc 35100 tggtgctgct cctggtagta ctgttacctc aacaaattca aatacatttt ctagttttga 35160 aaatgatgaa aaatcaatgg ctaaattgaa taaattagtt gaatttttcg aatcgagaac 35220 taataatcaa gatgatttgg aaaaatggtc aagtatgaaa acatcggaaa tatttggtga 35280 tcaagaagaa gaatattttg ctgatagtga agttgtacca tcatataaat caatattccc 35340 taatggtggt aatgctaata ataccaaact aatagctgaa cctacacctg aagctgatgc 35400 tggtgccaca tcagattctt ctgaagatat ggttgtcaca tatattaatc atcctcgtaa 35460 atcaatgaag aatgataaaa tgttgttatt cttttggata ccggcattag taatcatgtt 35520 gtttaccttc tttatggtat atgtggtggg atatcaattg aatgattatt ccattgttga 35580 aaaaatgttg aattgtactt ctttactaag gtgatattaa taaaaaccta ttgcaggata 35640 atataatatg attttttttt ttcacttcat ggtcagtttt tagtatatat gcttgtttca 35700 gctgctttta atttttagaa tgtttacctt tcaatttaat ttaatttaat ttaccttttc 35760 ttgtttaata ttagttttcg gtatgtgttg tgttgctaca tttttatgac ttgagtctat 35820 ttacttagtt tgtatttgtt tattaatata atgagtttta ataatatcaa gttaattgat 35880 taattaacta atatgtctat ttacataaac catcacgata tcttgaagta tcaattctca 35940 tgaattctct taatgccatt gtagcatatg aactaacacc taattgcatt cttaaaacca 36000 ctgccaattt attaccccct tccttatcgt cgttaataat tctatccggt aactctattg 36060 gagtagtgac agatttttgc gatgatttct tttcttgttc ttttttcaaa tttaataatt 36120 ctaaatcagt tctaatcaat ggtttttctc catctcctgt ttcaccatct tcgccttcct 36180 cagttttata tttgatgagt tcaaatgata aattattagc ttttgccatt aattttctat 36240 aagtaccagt taaagaaaat tctttttgtt ttctaatcat tttaaatgga tttaatccat 36300 ctttctccat aatatcaata taaacttgtt ttaaaattgg atttgtcgga tattcaattt 36360 tataacctgg tgatggtaat atcacatcaa atatagtata tttacctgat tcaatatctt 36420 gttttgttaa tgatctaact ttagcttcat taagataaac tacatcctca tcaacaatgt 36480 caggattagt gatagggtct tcaaacacta agtcaccttc gattaaattt aatccatata 36540 attcgattct ttttgatgct actaaattcc aaatatatgc ttgatatgca tgtccataca 36600 tcatacgaag atttttcgga attgcttgaa tggctttaag ataagaattt gaagaataaa 36660 cggtattgtt gtcatctttt tgttgcggtg attcattttg taaaactctt aaaacggcag 36720 tttcagcaac aaaataatga ggtaatttat tcaaagttaa tttaggatct ctagtttgtt 36780 tccaaatttt tctagcttca attgaaccag gtgcaactga ttcttgatca gataataaca 36840 attcaacaaa ttcttgccaa ttttcattta aaataaattt cccaaattca tgagttgata 36900 tactaaatga accaaatctt tgcattccaa aataatttat aaatccattt ttttgtaaac 36960 tttcaaaaca tgaagtaaca attgattcaa tggattgtga ttgatcctgg ggctgttgct 37020 cttgttgttg ttgttgttga tgatgaggtt ttatatctct aataacaatc gtgaattcat 37080 taccttttaa atcacctaat tttaatggat gatcctcata actaaatgac cctaatgtga 37140 atccattcct tttcagttta tttaatgcat tgactcgtaa tactttacca tgattgatac 37200 taaatctttg acatgtggca ccacgacgat ctttagtacc agcataattt ataaatttat 37260 gattaattct taataatttc ccaatattat tagcaacttc cattgtgtca cgattttgtt 37320 tataaaccgt gaaatgtaaa tatggtttat aaggacctaa cccataatta atgactccat 37380 tttcatcaat atgatgcata ctttcttgaa attgccttgg ttgttgtcta ctaccaccat 37440 tacgatttct tgatgatatg gcaattttaa aagtgttttc cagtgatgta atagtttcta 37500 atttattttg aaaaaccttt ctaaataatt gatgtaattt ggttcgttgt tctttatcat 37560 caaatttagt ttcagtttca aaatttttcc cattatgaaa taattgttca acttgtttca 37620 attcttcaac agtaataaat ttcaataatt cttcacgatc ttcatcagat atttttggat 37680 gtttatttga ttcaccacca tcaccaccat tgtcgtcagc ctctttcgat ctttgttgtt 37740 gttctttttc ttgttgtttg gcagctttta tttcagcgat ttcttcttca gttttacctt 37800 caatttcttg acgaaattta gctcgttctt gtaatttcaa ttctcttttt gatggtccaa 37860 catcaatacc atcatcaatt aaatgaatta cattacctaa tgggtcaatt tcattgactt 37920 ggaaatcaga atgtaatgtt tttaataatc cagaaaaccc agttatatta ggattaataa 37980 attgagtaat accagctttg gtttcactga ttcccataag agttggtttc aattttttag 38040 caacattact actactacca ctgccatcat tgattaaatt ggtttgagtt gccaatattt 38100 cttgatcttg tggaaatgat cttttaagtg attcagacat gattcgtgta attgtacgta 38160 accaatgtct tatcatacat atataaagaa agattattca gcataatata tgttggtaaa 38220 tgtattgaat gatttttttt ttcaactgag aaggagatga gcttacatca aaataggtcg 38280 gatttacatt tcttacaaga acattcaata atcagcaaag aaatatacag ctacatacac 38340 ttgtgtggat ctttaatgtt atatataaat aggttgacca tctaagttac catagtaata 38400 cttacgaagt atcacttttt agcacaattt gaagtagtac tttcaatcta cctatagctc 38460 ccacgcctct cccccttttt aatccctttc acaatccgtc tattcctata attttgctca 38520 ataacggtca tcaaacagtt atcaatttct tataatcttc tttcaattgc cattcttttt 38580 gaggtcattg attgtttgct acttgcaagg aggaggttaa gcctcattca gatcttttat 38640 cacgtgccaa ctaacattac gtaatgattt ttggggtcgt cagttggaaa gaagaaaacg 38700 agagaggggc cattgcattc acacacgcaa ttacaaacat caacaacaac aagttaatca 38760 atttcattta aaacccatcc atagatacat caattagtta ttacccactt cttgtattaa 38820 tccctttact taacaatgtc aactgatcat cattcccatc cagttgaagg acatcaattc 38880 aaaaaaatct ttaatcgttt aagtggacaa ccagaatcat atagtcgtaa acaaaattat 38940 acttttggta agactttagg agcaggatca tttggaattg ttagatatgc tagagataat 39000 agtactgatg aagaagtagc tgtgaaaata attttgaaaa aagctcttaa aggtaatgaa 39060 tcaatgatta ttgatgaaat gcaattgtta gaacaattaa ataaccctca tattgttgga 39120 tttagagatt ggtttgaaag taaagataaa ttttatttag tgactcaatt agccactgga 39180 ggagaattat ttgatcgaat tgttcaaaaa ggtcgattca ctgaacatga tgcttcatta 39240 gtagtacttc aaatgttgga agctttggaa tatttacata ataaagatat tgttcatcgt 39300 gatattaaac ccgaaaatat attatattta acttcaaaag atgattcccc cattgtgttg 39360 gcagattttg gtattgctaa acgattacaa aatcctaatg aaaaattgac ttcatctgct 39420 ggatcatttg gatatgctgc ccctgaagtc atattaggta ctggtcatgg taaaccttgt 39480 gacatttggt cattaggtgt ggttacttat actttattat gtggatattc tccatttaga 39540 tcagaaaatg ttcaagattt cattaatgaa gtgaaacata ataatgctgt gattttccat 39600 gctgattatt ggaaagatgt ctccaaagat gccagaagat ttattatcaa ggcattacaa 39660 ttcaaccctg ataatcgccc taccgccact gaattattaa atgatccatg gttagtttct 39720 attgctaaag aatataagga aaccgattta ttacctaatt tcaaacaagg atttgatgcc 39780 aagaagaaat tcagacaagc aattgaattg gtgaaattga ataatagaat taagaaattg 39840 aaagaatggc aaactgatga agatgatgat c 39871 // |
|