EBI Dbfetch

ID   AL023591; SV 1; linear; genomic DNA; STD; PRO; 38807 BP.
XX
AC   AL023591;
XX
DT   16-MAY-1998 (Rel. 55, Created)
DT   16-APR-2005 (Rel. 83, Last updated, Version 6)
XX
DE   Mycobacterium leprae cosmid B1259.
XX
KW   4-aminobutyrate aminotransferase; Acyl-CoA synthetase;
KW   alanyl-tRNA synthetase; alaS; antigen T5; aspartyl-tRNA synthetase; aspS;
KW   fadD9; gabT; GTP pyrophosphokinase; hisS; histidyl-tRNA synthetase;
KW   peptidyl-prolyl cis-trans isomerase; ppi;
KW   protein export membrane protein SecD; protein export membrane protein SecF;
KW   relA; secD; secF.
XX
OS   Mycobacterium leprae
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium.
XX
RN   [1]
RP   1-38807
RA   Devlin K., Churcher C.M.;
RT   ;
RL   Unpublished.
XX
RN   [2]
RP   1-38807
RA   Barrell B.G., Rajandream M.A.;
RT   ;
RL   Submitted (15-MAY-1997) to the EMBL/GenBank/DDBJ databases.
RL   Mycobacterium leprae sequencing project, Sanger Centre, Wellcome Trust
RL   Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: barrell@sanger.ac.uk
RL   Cosmids supplied by Dr. Stewart T. Cole, [3] Unite de Genetique Moleculaire
RL   Bacterienne, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex
RL   15, France Requests for cosmids should be sent to Karin Eiglmeier
RL   (kei@pasteur.fr).
XX
RN   [3]
RP   1-38807
RX   DOI; 10.1111/j.1365-2958.1993.tb01111.x
RX   PUBMED; 8446027.
RA   Eiglmeier K., Honore N., Woods S.A., Caudron B., Cole S.T.;
RT   "Use of an ordered cosmid library to deduce the genomic organization of
RT   Mycobacterium leprae";
RL   Mol. Microbiol. 7(2):197-206(1993).
XX
CC   Notes:
CC   
CC   The Sanger Centre is funded to complete the sequence of M. leprae
CC   by the Heiser Program for Research in Leprosy and Tuberculosis of
CC   The New York Community Trust.
CC   
CC   Work in Paris is supported by the Heiser Trust, the Association
CC   Francaise Raoul Follereau and the Groupement de Recherches et des
CC   Etudes des Genomes (GIP-GREG).
CC   
CC   Details of M. leprae sequencing at the Sanger Centre
CC   are available on the World Wide Web.
CC   (URL, http://www.sanger.ac.uk/Projects/)
CC   
CC   CDS are numbered using the following system eg MLCB33.01c.
CC   ML (M. leprae), cB33 (cosmid name), .01 (first CDS),
CC   c (complementary strand).
CC   
CC   The more significant matches with motifs in the PROSITE
CC   database are also included but some of these may be fortuitous.
CC   
CC   The length in codons is given for each CDS.
CC   
CC   Usually the highest scoring match found by fasta -o is given for
CC   CDS which show significant similarity to other CDS in the database.
CC   The position of possible ribosome binding site sequences are
CC   given where these have been used to deduce the initiation codon.
CC   
CC   All CDS over 100 codons have been analysed.  Gene prediction
CC   is based on positional base preference in codons especially
CC   where there is an increase in the observed/expected third
CC   position G + C.  CAUTION:  We may not have predicted the
CC   correct initiation codon.  Where possible we choose an
CC   initiation codon (atg, gtg, or ttg) which is preceded by an
CC   upstream ribosome binding site sequence (optimally 5-13bp
CC   before the initiation codon).  If this cannot be identified
CC   we choose the most upstream initiation codon.
CC   
CC   IMPORTANT: This sequence MAY NOT be the entire insert of
CC   the sequenced clone.  It may be shorter because we only
CC   sequence overlapping sections once, or longer, because we
CC   arrange for a small overlap between neighbouring submissions.
CC   
CC   Cosmid B1259 overlaps EMBL:ML011 B1177 at the 5' end and
CC   EMBL:MLB937CS B937 at the 3' end.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..38807
FT                   /organism="Mycobacterium leprae"
FT                   /mol_type="genomic DNA"
FT                   /clone="cosmid B1259"
FT                   /db_xref="taxon:1769"
FT   misc_feature    complement(1..20510)
FT                   /note="overlap with ML011 U00011 Mycobacterium leprae
FT                   cosmid B1177 from: 2 to: 20509. There are seven conflicts
FT                   between this sequence and EMBL:ML011; our sequence has been
FT                   checked, and is thought to be correct"
FT   CDS             complement(<1..80)
FT                   /transl_table=11
FT                   /gene="MLCB1259.01c"
FT                   /product="hypothetical protein MLCB1259.01c"
FT                   /note="MLCB1259.01c, unknown, partial CDS, len: >26 aa;
FT                   identical to start of TR:Q49654 (EMBL:U00011) B1177_F2_71
FT                   (78aa)"
FT                   /db_xref="UniProtKB/TrEMBL:Q7ARP1"
FT                   /protein_id="CAA19076.1"
FT                   /translation="MAPKHHQRLGRRQADPLVSIEQHRSQR"
FT   RBS             complement(82..89)
FT                   /note="possible RBS upstream of MLCB1259.01c"
FT   CDS             complement(213..3737)
FT                   /transl_table=11
FT                   /gene="fadD9"
FT                   /product="putative Acyl-CoA synthetase"
FT                   /note="MLCB1259.02c, fadD9, probable Acyl-CoA synthetase,
FT                   len: 1247 aa; highly similar to M. tuberculosis Acyl-CoA
FT                   synthetase TR:Q50631 (EMBL:Z77724) MTCY227.11c fadD9 (1168
FT                   aa), fasta scores; opt: 5247 z-score: 4713.9 E(): 0, 68.0%
FT                   identity in 1178 aa overlap. Contains PS00455 Putative
FT                   AMP-binding domain signature and PS00061 Short-chain
FT                   dehydrogenases/reductases family signature. Equivalent to
FT                   the two ORFs TR:Q49651 (827 aa) and TR:Q49653 (400 aa) from
FT                   the overlapping cosmid B1177 (EMBL:U00011). The difference
FT                   is due to a frameshift in the overlapping cosmid."
FT                   /db_xref="GOA:O69484"
FT                   /db_xref="InterPro:IPR010080"
FT                   /db_xref="UniProtKB/TrEMBL:O69484"
FT                   /protein_id="CAA19077.1"
FT                   /translation="MSTITKQEKQLARRVDDLTANDPQFAAAKPDPAVAAALAQPGLRL
FT                   PQIIQTALDGYAERPALGQRVAEFTKDPKTGRTSMELLPSFETITYRQLGDRVGALARA
FT                   WRHDLLHAGYRVCVLGFNSVDYAIIDMALGVIGAVAVPLQTSAAITQLQSIVTETEPSM
FT                   IATSVNQLPDTVELILSGQAPAKLVVFDYHPEVDEQHDAVATARARLADSSVVVESLTE
FT                   VLGRGKTLPATPIPVADDSADPLALLIYTSGSTGAPKGAMYLQSNVGKMWRRSDGNWFG
FT                   PTAASITLNFMPMSHVMGRGILYGTLGNGGTAYFAARSDLSTLLEDLKLVRPTELNFVP
FT                   RIWETLYDESKRAVDRRLANSGSADRAAIKAEVMDEQRQSLLGGRYIAAMTGSAPTSPE
FT                   LKHGVESLLEMHLLEGYGSTEAGMVLFDGEVQRPPVIDYKLVDVPDLGYFSTDQPYPRG
FT                   ELLLKTQNMFPGYYKRPEVTATVFDSDGYYQTGDIVAEVGPDRLVYVDRRNNVLKLAQG
FT                   QFVTVAKLEAAFSNSPLVRQIYIYGNSAHPYLLAVVVPTEDALATNDIEVLKPLIIDSL
FT                   QKVAKEADLQSYEVPRDLIVETTPFSLENGLLTGIRKLAWPKLKQHYGARLEQLYADLV
FT                   EGQANALHVLKQSVANAPVLQTVSRAVGTILGVATTDLPSNAHFTDLGGDSLSALTFGS
FT                   LLRELFDIDVPVGVIVSPVNNLVAIADYIERERQGTKRPTFIAIHGRDAGKVHASDLTL
FT                   DKFIDVSTLTAAPVLAQPGTEVRTVLLTGATGFLGRYLALKWLERMDLVEGKVIALVRA
FT                   KSNEDARARLDKTFDSGDPKLLAHYQELATDHLEVIAGDKGEVDLELDRQTWRRLADTV
FT                   DLIVDPAALVNHVLPYSELFGPNTLGTAELIRIALTSKQKPYIYVSTIGVGNQIEPAKF
FT                   TEDSDIRVISPTRNINNNYANGYGNSKWAGEVLLREAHDLCGLPVTVFRCDMILADTSY
FT                   AGQLNVPDMFTRMMLSLAATGIAPGSFYELDAESNRQRAHYDGLPVEFIAEAISTLGDQ
FT                   SLHDRDGFTTYHVMNPHDDGIGMDEFVDWLIDAGCPIQRINDYDEWLRRFEISLRALPE
FT                   RQRHSSLLPLLHNYQKPEKPLHGSLAPTIRFRTAVQNANIGQDKDIPHISPAIIAKYVS
FT                   DLQLLGLV"
FT   misc_feature    complement(834..920)
FT                   /note="PS00061 Short-chain dehydrogenases/reductases family
FT                   signature"
FT   misc_feature    1431..1432
FT                   /note="conflict: CG is CTG in EMBL:MLB937CS"
FT   misc_feature    complement(2961..2996)
FT                   /note="PS00455 Putative AMP-binding domain signature"
FT   RBS             complement(3745..3749)
FT                   /note="possible RBS upstream of fadD9"
FT   CDS             complement(3875..5215)
FT                   /transl_table=11
FT                   /gene="gabT"
FT                   /product="4-aminobutyrate aminotransferase"
FT                   /note="MLCB1259.03c, gabT, 4-aminobutyrate
FT                   aminotransferase, len: 446 aa; identical to GABT_MYCLE,
FT                   highly similar to e.g. GABT_ECOLI (EC 2.6.1.19) (426 aa),
FT                   fasta scores; opt: 1186 z-score: 1515.2 E(): 0, 43.1%
FT                   identity in 422 aa overlap. Contains PS00600
FT                   Aminotransferases class-III pyridoxal-phosphate attachment
FT                   site"
FT                   /db_xref="GOA:P40829"
FT                   /db_xref="HSSP:1QJ3"
FT                   /db_xref="InterPro:IPR015421"
FT                   /db_xref="UniProtKB/Swiss-Prot:P40829"
FT                   /protein_id="CAA19078.1"
FT                   /translation="MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPVFVTRA
FT                   AGGVIEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQVADFTHTCFIITPYEEYVAV
FT                   TEQLNRITPGSGEKRSVLFNSGAEAVENSIKVARSYTRKPAVVAFDHAYHGRTNLTMAL
FT                   TAKSMPYKSGFGPFAPEIYRAPLSYPYRDGLLNKDLATDGKLAGARAINVIEKQVGADD
FT                   LAAVIIEPIQGEGGFIVPAEGFLATLLDWCRKNNVMFIADEVQTGFARTGAMFACEHDG
FT                   IVPDLICTAKGIADGLPLAAVTGRAEIMNAPHVSGLGGTFGGNPVACAAALATITTIEN
FT                   DGLIQRAQQIERLITDRLLRLQDADDRIGDVRGRGAMIAVELVKSGTAEPDPELTEKVA
FT                   TAAHATGVIILTCGMFGNIIRLLPPLTISDELLAEGLDILSRILGDF"
FT   misc_feature    complement(4328..4441)
FT                   /note="PS00600 Aminotransferases class-III
FT                   pyridoxal-phosphate attachment site"
FT   RBS             complement(5222..5227)
FT                   /note="possible RBS upstream of gabT"
FT   CDS             5484..5828
FT                   /transl_table=11
FT                   /gene="MLCB1259.04"
FT                   /product="putative secreted protein"
FT                   /note="MLCB1259.04, probable secreted protein, len: 114 aa;
FT                   equivalent to Y0BD_MYCTU MTCY227.13 (115 aa),  opt: 499
FT                   z-score: 927.0 E(): 0, 77.0% identity in 100 aa overlap.
FT                   Identical to, but longer than, Y0BD_MYCLE, due to more
FT                   upstream start used in order to include signal sequence."
FT                   /db_xref="GOA:Q49647"
FT                   /db_xref="InterPro:IPR003849"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q49647"
FT                   /protein_id="CAA19079.1"
FT                   /translation="MESLVLLLLFLLIMGGFMFFASRRQRRSMQATIDLYNSLQPGDRV
FT                   NTTSGLQATIIVVGDDTVDLEIAPGVVTTWMKLAIRDRILPDDAYMDEHEAEPGDFVYC
FT                   DELEESDGSS"
FT   RBS             5939..5943
FT                   /note="possible RBS upstream of secD"
FT   CDS             5946..7661
FT                   /transl_table=11
FT                   /gene="secD"
FT                   /product="protein export membrane protein SecD"
FT                   /note="MLCB1259.05, secD, protein export membrane protein
FT                   ,len: 571 aa; similar to many e.g. SECD_STRCO
FT                   protein-export membrane protein secD (570 aa), fasta
FT                   scores; opt: 858 z-score: 924.8 E(): 0, 37.5% identity in
FT                   566 aa overlap. Differs from SECD_MYCLE due to frameshift
FT                   errors in the previous sequence"
FT                   /db_xref="GOA:P38387"
FT                   /db_xref="InterPro:IPR003335"
FT                   /db_xref="UniProtKB/Swiss-Prot:P38387"
FT                   /protein_id="CAA19080.1"
FT                   /translation="MASSSAPVHFGRYLSMFLVLFIGVYLLAFLTGDKRVVPRLGIDLQ
FT                   GGTRVTLTARTPDGSRPSREALSQAQQIISSRVNGLGVSGSEVVVDGDNLVITVPGNDG
FT                   NEARNLGQTARLYIRPVLNSLPVQRGQDPKPGSPAGTLPNFAPMPPDHPGAQPRPYLQD
FT                   PTSSPSSDPMPSPVPTGAALPGEVPSVEQPAPPDPRKDLAERIAEEKKWRQSTKQSIQF
FT                   LALQFESTHCDKDDILAGNDDPNLPLATCSTDHNMAYLLAPSIISGDQIQNSTSGMNQR
FT                   GVGYVVDLQFKSAAADVWADFTAAHIGTQTAFTLDSEVVSVPVINEAILGGRTQISGGD
FT                   PPFTAATARQLANVLKYGSLPLSFEPSEAQTVSATLGLTSLRAGLIAGAIGLSLVLLYS
FT                   LLYYRVLGLLTAFSLFCSGTIIFAILVLLGRYINYTLDLAGIAGLIIGIGTTADSFVVF
FT                   FERIKDEIREGRSFRSAVPRGWVRARKTIVSGNAVTFLAAAVLHFLAIGQVKGFAFTLG
FT                   LTTILDLVVVFLVTWPLVYLASKSPLLARPAYNGLGAVQQVARERRASAKTGRG"
FT   misc_feature    6131..6132
FT                   /note="conflict: these bases are missing in EMBL:MLB937CS"
FT   misc_feature    7643..7643
FT                   /note="conflict: this base is missing in EMBL:MLB937CS"
FT   CDS             7666..9081
FT                   /transl_table=11
FT                   /gene="secF"
FT                   /product="protein export membrane protein SecF"
FT                   /note="MLCB1259.06, secF, protein export membrane
FT                   protein,len: 471 aa; similar to many e.g. SECF_STRCO (373
FT                   aa), fasta scores; opt: 634 z-score: 994.5 E(): 0, 35.9%
FT                   identity in409 aa overlap. Differs from SECF_MYCLE due to
FT                   frameshifterrors in the previous sequence"
FT                   /db_xref="GOA:P38386"
FT                   /db_xref="InterPro:IPR005665"
FT                   /db_xref="UniProtKB/Swiss-Prot:P38386"
FT                   /protein_id="CAA19081.1"
FT                   /translation="MVSRAKVGAETTKGIDEPDRNDNTDDNGAGAVEVTEAAEDAVELT
FT                   NDISTQLPQHGFLARFYTGLSRLYTGTGVFEVVGRRRLWYSVGGVIVAVAVLSIIVRGF
FT                   TFGIDFKGGTTVSMPVSPGVGGTGAIEVAQVADVFKKTLGSDPESVVVVGNGASATVRI
FT                   SSKTLSNDQTSKLRNALFDAFGPKGADAKPSKQAISDAAVSETWGGQITKKVVIALVVF
FT                   LVLVGLYITVRYERYMAISALTTMCFDLTVTAGVYSLVGFEVTPATVIGLLTILGFSLY
FT                   DTVIVFDKVEENTHGFQHTTRRTFAEQANLAINQTFMRSINTSLISVLPVLALMVVAVW
FT                   LLGVGTLKDLALVQLVGIIVGTYSSIFFATPLLVTLRERTELVRTHTRRVVKRRTLGSQ
FT                   VGKKNADSHVAAGTRKPQNQAESCADASSQEGTEVATASVPTVLSKLAPGVRPVRPTGT
FT                   RRPTGKRNNVGRR"
FT   misc_feature    7836..7836
FT                   /note="conflict: this base is missing in EMBL:MLB937CS"
FT   CDS             9125..10792
FT                   /transl_table=11
FT                   /gene="MLCB1259.07"
FT                   /product="putative lipoprotein"
FT                   /note="MLCB1259.07, unknown, possible lipoprotein, len: 555
FT                   aa; equivalent to M. tuberculosis hypothetical protein
FT                   Y0BG_MYCTU MTCY227.16 (557 aa), fasta scores; opt: 2812
FT                   z-score: 1928.5 E(): 0, 78.9% identity in 546 aa overlap.
FT                   Coversthe same region as Y0BG_MYCLE and TR:Q49638 DCIAE
FT                   protein (344 aa) but differs from these due to frameshift
FT                   errors inthe previous sequence. Contains possible
FT                   N-terminal signalsequence and appropriately positioned
FT                   PS00013 Prokaryotic membrane lipoprotein lipid attachment
FT                   site"
FT                   /db_xref="GOA:Q49646"
FT                   /db_xref="InterPro:IPR000914"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q49646"
FT                   /protein_id="CAA19082.1"
FT                   /translation="MRSGLFGVLRWTAVGLVATLVASLALTACSGSAAGEIVYVVDGAL
FT                   GTYNTNTIVGAASAGAQAFARTLIGFGYHGPDGQIVADHDFGTITVVGGVPLVLDYQIA
FT                   DNAVYSDGKQVTCDDLVLTWAAQSGRFPGFDAATQAGYRDIANIECLAGQKKSRVFFVP
FT                   DRSVVDYEQLFAATSMMPSHVIADQLNIDVTEALLTHNATLVEQIARLWNTTWDLKPAV
FT                   DLRRFPSSGPYKIESVLNGGAVVLVANDRWWGLKATTKRITVRPQEADIQDRVNNRSVD
FT                   VVDVAVGSSGSLATPDNYARIDSPSAGIEQLIFAPQGLLAAAAARRALALCTPRDVVAR
FT                   DAGLSIANSRLSPATEDAIAAADGAREAGQFSKADPAAAHDALSGETLPVRIGYQGPNA
FT                   RLAATVGTIAKACAVAGISVSSVTLDSSTDPSGPQALRDGKIDVLLASTGGATGSGSSG
FT                   SSSMDAYDLHTGNGNNLSGYANAQVDNNIGALAVSADPAERVRLLADSAPVLWADMPTL
FT                   PLYRQQRMLLMSKTMYAVTRNPTRWGAGWNMDRWALVR"
FT   misc_feature    9126..9127
FT                   /note="conflict: TG is TTG in EMBL:MLB937CS"
FT   misc_feature    9179..9211
FT                   /note="PS00013 Prokaryotic membrane lipoprotein lipid
FT                   attachment site"
FT   CDS             10816..11338
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1259.08, probable adenine
FT                   phosphoribosyltransferase pseudogene, equivalent to
FT                   APT_MYCTU (223 aa)"
FT   RBS             11425..11430
FT                   /note="possible RBS upstream of relA"
FT   CDS             11438..13801
FT                   /transl_table=11
FT                   /gene="relA"
FT                   /product="GTP pyrophosphokinase"
FT                   /note="MLCB1259.09, relA, GTP pyrophosphokinase, len: 787
FT                   aa; siimilar to many e.g. RELA_STRCO GTP pyrophosphokinase
FT                   (EC 2.7.6.5) (847 aa), fasta scores; opt: 1627 z-score:
FT                   3190.5 E(): 0, 63.3% identity in 800 aa overlap. Identical
FT                   to RELA_MYCLE"
FT                   /db_xref="GOA:Q49640"
FT                   /db_xref="InterPro:IPR004095"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q49640"
FT                   /protein_id="CAA19084.1"
FT                   /translation="MADDQGTAQALQPVQVVPGPAVEAPETPVETLKTSSSASRRVRAR
FT                   LARRMTAQRSTISPVLEPLVAVHKEFYPKANLSIVQRAFEVADQRHASQLRRSGDPYIT
FT                   HPLAVANILAELGMDITTLVAALLHDTVEDTGYTLEALSEEFGDEVGHLVDGVTKLDRV
FT                   VLGSAAEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIA
FT                   PLAHRLGMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIISTLGA
FT                   SKIKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVGVVHSLWQ
FT                   PMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEA
FT                   KGRNGVLHPHAAAEIDDMAWMRQLLDWQREAAEPGEFLESLRYDLAVQEIFVFTPKGDV
FT                   ITLPTGSTPVDFAYAVHTEVGHRCIGARVNGRLVALERKLENGEFVEIFTSKAPNAGPS
FT                   RDWQQFVVSPRAKTKIRQWFAKERREEALEAGKDAMAREVRRGGLPLQRLVNGESMAAV
FT                   ARELHYIDVSALYTAIGEGHVSARHVVQRLLAELGGIDQAEEELAERSTPTTMLRRQRS
FT                   TDDVGVSVPGAPGVLTKLAKCCTPVPGDAIMGFVTRGGGVSVHRTDCTNTASLQQQAER
FT                   IIEVLWAPSSSSVFLVAIQVEALDRHRLLLDITRALADERVDILSASVTTSGDRVAISR
FT                   FTFEMGDPKHLGHLLNVVRNVEGVYDVYRVMSAS"
FT   CDS             complement(13860..14747)
FT                   /transl_table=11
FT                   /gene="ppi"
FT                   /product="peptidyl-prolyl cis-trans isomerase"
FT                   /note="MLCB1259.10c, ppi, probable peptidyl-prolyl
FT                   cis-trans isomerase, len: 295 aa; similar in C-terminus to
FT                   many e.g. CYPB_ECOLI peptidyl-prolyl cis-trans isomerase B
FT                   (164 aa), fasta scores; opt: 127 z-score: 190.6 E():
FT                   0.0022, 32.2%identity in 174 aa overlap. Identical to
FT                   CYPH_MYCLE"
FT                   /db_xref="GOA:P46697"
FT                   /db_xref="HSSP:1H0P"
FT                   /db_xref="InterPro:IPR002130"
FT                   /db_xref="UniProtKB/Swiss-Prot:P46697"
FT                   /protein_id="CAA19085.1"
FT                   /translation="MPTNEQRRATAKRKLKRQLERRAKQARWRRVLLISGGVVVAVAVI
FT                   ITVVATVVISKLGHKHDTASSTASNSLTATKTPAVTPSVLPLPSFQPSTNLGVNCQYPP
FT                   SADKAAKPVKPPRAGKVPTDPATVSASMATNQGNIGLLLNNAESPCTVNSFASLTGQGF
FT                   FNNTKCHRLTTSLMLGVLQCGDPKVDGTGGPGYKFANEYPTDQYPPNDPKLKQPVLYPR
FT                   GTLAMANSGPNTNGSQFFLVYHDSQLPPEYTVFGTIQADGLATLDKIAKGGIASGGDDG
FT                   PPATEVTIESLRLD"
FT   RBS             complement(14758..14762)
FT                   /note="possible RBS upstyream of ppi"
FT   CDS             14911..15567
FT                   /transl_table=11
FT                   /gene="MLCB1259.11"
FT                   /product="hypothetical protein MLCB1259.11"
FT                   /note="MLCB1259.11, unknown, len: 218 aa; possible
FT                   glyoxalase, similar to hypothetical proteins from many
FT                   organisms e.g. YCBL_ECOLI (215 aa), fasta scores;opt: 397
FT                   z-score: 599.0 E(): 3.9e-26, 36.4% identity in 214 aa
FT                   overlap. Also similar to members of the glyoxalase II
FT                   family e.g. GLO2_YEASThydroxyacylglutathione hydrolase
FT                   isozyme 1 (274 aa)initn:213  init1: 56  opt:   91 z-score:
FT                   334.3 E(): 2.2e-11Smith-Waterman score: 220;    27.5%
FT                   identity in 229 aa overlap. Identical to Y0BK_MYCLE"
FT                   /db_xref="GOA:Q49649"
FT                   /db_xref="InterPro:IPR001279"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q49649"
FT                   /protein_id="CAA19086.1"
FT                   /translation="MLITGFPAGMLQCNCYVLADRAGTDAVIVDPGQRAMGPLRRILDE
FT                   NRLTPSAVLLTHGHIDHMWSAQKVSDTYGCPTYIHPEDRFMLTDPLFGFGPRVAQVVTG
FT                   AFFREPKQVVELDRDGDKLDLGSVTVNVDHTPGHTRGSVCFWVAADTDVVLTGDTLFER
FT                   TIGRTDLFGGSGRDLYRSIVEKLLVLDDKTVVLPGHGNSTTIGAERRFNPFLEGL"
FT   RBS             15556..15559
FT                   /note="possible RBS upstream of hisS"
FT   CDS             15571..16854
FT                   /transl_table=11
FT                   /gene="hisS"
FT                   /product="histidyl-tRNA synthetase"
FT                   /note="MLCB1259.12, hisS, histidyl-tRNA synthetase, len:
FT                   427 aa; highly simiar to many e.g. SYH_ECOLI histidyl-tRNA
FT                   synthetase (EC 6.1.1.21) (423 aa), fasta scores; opt: 1031
FT                   z-score: 1188.8 E(): 0, 42.1% identity in 413 aa overlap.
FT                   Identical to SYH_MYCLE. Contains PS00017 ATP/GTP-binding
FT                   sitemotif A (P-loop)"
FT                   /db_xref="GOA:P46696"
FT                   /db_xref="HSSP:1QE0"
FT                   /db_xref="InterPro:IPR004154"
FT                   /db_xref="UniProtKB/Swiss-Prot:P46696"
FT                   /protein_id="CAA19087.1"
FT                   /translation="MTESCTVFSFSGPKGIPDYFPPDSAQFVAVRDGLLTAARRAGYGD
FT                   IELPVFEDTALFARGVGESTDVVAKEMYTFADRGDRSVTLRPEGTAGVVRAVIEHGLDR
FT                   GALPVKLCYAGPFFRYERPQAGRCRQLQQVGVEAIGVDDPALDAEVITIADAGFRSLGL
FT                   DGFQLEITSLGDGTCRPQYRKLLQEFLLQLDLDEDTRRRAELNPLRVLDDKRPQVQAMT
FT                   AAAPVLLDHLSDGAKQHFDTVLAHLDALRVPYVINPRMVRGLDYYTKTTFEFVHPGLGA
FT                   QSGIGGGGRYDGLMRQLGGQDLSGIGFGLGVDRTLLALHAEGKTVGETTRCDVFGVSLG
FT                   EAAKLKVAMLAGQLRAAGVRVDLIYGDRGIRGAMRAAGRSGARIALIVDDCAIKADGVG
FT                   VRDLATGEQISVAVDSVVAEVISRIAPS"
FT   misc_feature    15691..15692
FT                   /note="conflict: CG is GC in EMBL:MLB937CS"
FT   misc_feature    16522..16545
FT                   /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
FT   CDS             16983..17407
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1259.13, probable pseudogene, similar to M.
FT                   tuberculosis PE family proteins e.g. TR:O07174
FT                   (EMBL:Z96071) MTCI418B.06 (487 aa)"
FT   CDS             17581..18159
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1259.14, probable pseudogene, equivalent to M.
FT                   tuberculosis hypothetical protein Y0BN_MYCTU MTCY227.23
FT                   (340 aa)"
FT   misc_feature    18128
FT                   /note="conflict: this base is missing in EMBL:MLB937CS"
FT   CDS             complement(18170..19659)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1259.15c, probable pseudogene, equivalent to
FT                   M.tuberculosis hypothetical protein Y0BO_MYCTU MTCY227.24c
FT                   (529 aa)"
FT   CDS             19832..20259
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1259.16, probable pseudogene, equivalent to M.
FT                   tuberculosis hypothetical protein Y0BP_MYCTU MTCY227.25
FT                   (154 aa)"
FT   CDS             complement(21024..21846)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1259.17c, probable pseudogene, equivalent to
FT                   M.tuberculosis hypothetical protein Y0BQ_MYCTU MTCY227.26c
FT                   (293 aa)"
FT   CDS             complement(21936..22423)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1259.18c, probable pseudogene, equivalent to
FT                   M.tuberculosis hypothetical protein Y0BS_MYCTU MTCY227.28c
FT                   (246 aa)"
FT   misc_feature    complement(22590..24800)
FT                   /note="99.7% match to bp 1 to 2209 from S82268
FT                   ASPS=aspartyl-tRNA synthetase, antigen T5"
FT   misc_feature    22590..24439
FT                   /note="100% match to bp 1 to 1850 of MLASPS X77655 M.leprae
FT                   ASPS gene."
FT   RBS             22661..22664
FT                   /note="possible RBS upstream of aspS"
FT   CDS             22670..24439
FT                   /transl_table=11
FT                   /gene="aspS"
FT                   /product="aspartyl-tRNA synthetase"
FT                   /note="MLCB1259.19, aspS, aspartyl-tRNA synthetase, len:
FT                   589 aa; highly similar to many e.g. SYD_ECOLI aspartyl-tRNA
FT                   synthetase (EC 6.1.1.12) (ASP (590 aa), fasta scores; opt:
FT                   1538 z-score: 2022.9 E(): 0, 46.8% identity in 583 aa
FT                   overlap. Identical to SYD_MYCLE. Contains PS00179
FT                   Aminoacyl-transfer RNA synthetases class-II signature 1"
FT                   /db_xref="GOA:P36429"
FT                   /db_xref="HSSP:1L0W"
FT                   /db_xref="InterPro:IPR004365"
FT                   /db_xref="UniProtKB/Swiss-Prot:P36429"
FT                   /protein_id="CAA19094.1"
FT                   /translation="MLRSHGAGVLRKSDAGQQVTLAGWVSRRRDHGGVIFIDLRDSSGI
FT                   TQAVFREPDVLAQAHRLRAEFCIAVSGVVEIRPEGNANAEIPTGDIEVNATSLTVLGES
FT                   APLPFQLDEPAGEELRLKYRYLDLRRDGPGSAIRLRSKVNATARAVLARHDFVEIETPT
FT                   ITRSTPEGARDFLVPARLRPGTFYALPQSPQLFKQLLMVAGMERYYQIAHCYRDEDFRA
FT                   DRQPEFTQLDMEMSFVDAEDVIAISEEILTELWMLIGYHIPAPIPRISYADAMRRFGSD
FT                   KPDLRFGLELVECTEFFCDTTFRVFQAPYVGAVVMPGGAAQPRRTLDEWQDWAKQRGHR
FT                   GLAYVLVTDDGTLGGPVAKNFSDAERSRLASHVGAEPGDCIFFSAGPAKSSRALLGAAR
FT                   GEIANRLGLIDPEAWAFVWVVDPPLFERADEATKVGEMAVGSGAWTAVHHAFTSPKPEF
FT                   EDSIESDPGSVLADAYDIVCNGHEIGSGSVRINRRDIQERVFAVMGLEKAEAEEKFGFL
FT                   LEAFTFGAPPHGGIAFGWDRTNALLAGMESIREVIAFPKTGGGVDPLTDAPASITAQQR
FT                   KESGIDTKPKEVE"
FT   misc_feature    23312..23365
FT                   /note="PS00179 Aminoacyl-transfer RNA synthetases
FT                   class-IIsignature 1"
FT   CDS             complement(23819..24253)
FT                   /transl_table=11
FT                   /gene="MLCB1259.20c"
FT                   /product="antigen T5"
FT                   /note="MLCB1259.20c, antigen T5, len: 144 aa; identical to
FT                   TR:P95672 ANTIGEN T5 (144 aa) see Wieles B. et al.
FT                   Molecular characterization and T-cell-stimulatory capacity
FT                   of Mycobacterium leprae antigen T5; Infect. Immun.
FT                   63:4682-4685(1995). Note aspartyl-tRNA synthetase gene on
FT                   opposite strand."
FT                   /db_xref="UniProtKB/TrEMBL:P95672"
FT                   /protein_id="CAA19095.1"
FT                   /translation="MRRRTKRKSLQKEPEFLLRLSLFQSHNRKHPFLDITAVNTNRAAT
FT                   NLVAVTNDVVGIGQHAAGIGLYAVLEFRFRRCEGMMHRSPRTRAHCHFADLGGLVGAFE
FT                   KRRVDYPDERPGLGVDQTQPVGDLTAGGPQQCPRRLRRAR"
FT   CDS             27427..27837
FT                   /transl_table=11
FT                   /gene="MLCB1259.21"
FT                   /product="hypothetical protein MLCB1259.21"
FT                   /note="MLCB1259.21, questionable ORF len: 136 aa"
FT                   /db_xref="UniProtKB/TrEMBL:O69489"
FT                   /protein_id="CAA19096.1"
FT                   /translation="MYRGVDLRSPRRSGSVALRDAHRLYGDLGLGQRSCINKSDCGVTA
FT                   QVLHNVPRCRIVGLAPIRAKPVIGGKSDILGCGDDYAGDYPALQTAYPIGQYVRRDPAD
FT                   RGEHLGGHRQHGGSILVGEKRTILHHENASTA"
FT   CDS             complement(28488..29262)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1259.22c, probable transposase pseudogene,
FT                   similar to M. tuberculosis IS element ORF's e.g. TR:P71924
FT                   (EMBL:Z81451) MTCY428.23 probable transposase for IS1558
FT                   (333 aa)"
FT   stem_loop       28566..28619
FT                   /note="hairpin_loop with 26 bp stem"
FT   stem_loop       30447..30483
FT                   /note="hairpin_loop with 17 bp stem"
FT   CDS             complement(30464..30802)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1259.23c, probable pseudogene, equivalent to
FT                   M.tuberculosis hypothetical protein Y0BV_MYCTU CY227.31c
FT                   (129aa)"
FT   CDS             31148..32639
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1259.24, probable pseudogene, equivalent to M.
FT                   tuberculosis hypothetical protein TR:Q50731/Y0BY_MYCTU
FT                   MTCY9C4.01C/MTCY227.34C (EMBL:Z77250). Note that the match
FT                   to this protein extends into the downstream ORF
FT                   MLCB1259.25"
FT   RBS             32604..32608
FT                   /note="possible RBS upstream of MLCB1259.25"
FT   CDS             32612..34273
FT                   /transl_table=11
FT                   /gene="MLCB1259.25"
FT                   /product="hypothetical protein MLCB1259.25"
FT                   /note="MLCB1259.25, unknown, len: 553 aa; similar to
FT                   several M. tuberculosis hypothetical proteins. Highly
FT                   similar in the N-terminus to Y0BY_MYCTU MTCY227.34C (697
FT                   aa), fasta scores; opt: 705 z-score: 880.6 E(): 0, 54.6%
FT                   identity in 229 aa overlap and in the C-terminus to
FT                   Y0BW_MYCTU MTCY227.32(314 aa), fasta scores; opt: 1723
FT                   z-score: 2173.0 E(): 0, 84.4% identity in 301 aa overlap.
FT                   Note that these two M.t. proteins are convergently
FT                   transcribed and separated by another ORF, and that the
FT                   similarity to MTCY227.34C extends upstream of this ORF, but
FT                   in several different reading frames (annotated as
FT                   pseudogene MLCB1259.24)"
FT                   /db_xref="InterPro:IPR002931"
FT                   /db_xref="UniProtKB/TrEMBL:Q7ARN9"
FT                   /protein_id="CAA19100.1"
FT                   /translation="MDGARQCRVVTDAAVCIGPGDVWAVPRTGQTGQSSESSELADDIK
FT                   FAPVHATTLALSQVAAESVVRDVDLTMTNIGKRIERREWLTSLLEAISSKDRSRAAEQT
FT                   IIESTQMACESSVIYLRHNLRAVNVATVAELVLFEVENPRLLVYPLERLRTDLWQLPGA
FT                   SGSSRAERLADDISIRLRRLDPADFDVVTANGERAKLAGLLTGIHNGLLDPTDVTTATQ
FT                   LSLPGEMQPMWVPDQRWVMLSCHMKWTQLTSRRYRVSHRTEYRYSDVVTSSYGRGFLTP
FT                   CDSLRQRCVDHRLHIVPVPADSSISRDSYGNISSYFHVTEPHCTLTVTSESIVDVYPTP
FT                   PELFTSGPASAPWEAARPTGRRGVLATEFTLDLNPPEITDEVRQYAAPSFEPQRPLIEV
FT                   LRDLTTRIYADFTYRSGSTTISTGVNEVLLAREGVCQDFARLAIACLRANGLAASYVSG
FT                   YLATDPPPGKDRMVGIDVTHAWASVWTPQQSGQCEWLGLDPTNDQLVDERYIVVGQGRD
FT                   YVNVPPLRGIIYTNSENSVIDVAVDVAPCEGDALYA"
FT   misc_feature    32708..38807
FT                   /note="overlap with MLB937CS from 1 to 6103. There is one
FT                   conflict between this sequence and EMBL:MLB937CS; our
FT                   sequence has been checked, and is thought to be correct"
FT   CDS             34266..35284
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1259.26, probable pseudogene, equivalent to M.
FT                   tuberculosis hypothetical protein Y0BX_MYCTU MTCY227.33
FT                   (341 aa)"
FT   CDS             35575..36918
FT                   /transl_table=11
FT                   /gene="MLCB1259.27"
FT                   /product="hypothetical protein MLCB1259.27"
FT                   /note="MLCB1259.27, unknown, len: 447 aa; highly similar to
FT                   hypothetical proteins from many organisms e.g.
FT                   YCAJ_ECOLI(447 aa), fasta scores; opt: 1074 z-score: 1199.1
FT                   E(): 0, 42.7% identity in 417 aa overlap. Also similar to
FT                   helicasese.g. RUVB_ECOLI holliday junction dna helicase
FT                   ruvB (336 aa), fasta scores; opt: 160 z-score: 224.1 E():
FT                   3e-05, 25.8%identity in 291 aa overlap. Contains PS00017
FT                   ATP/GTP-binding site motif A (P-loop)"
FT                   /db_xref="GOA:O69490"
FT                   /db_xref="HSSP:1J7K"
FT                   /db_xref="InterPro:IPR003959"
FT                   /db_xref="UniProtKB/TrEMBL:O69490"
FT                   /protein_id="CAA19102.1"
FT                   /translation="MSDSLFDLPGAPQPTDYGLGGSTGVPLAVRMRPASLDELVGQGHL
FT                   LAPGSPLRRLVEGSGVVSAILHGPPGCGKTTLAALISQATGHRFEALSALSAGVKDVRA
FT                   VLKIARSALLSGKRTVLFIDEVHRFSKTQQDALLSAVENRVVLLVAATTENPSFSVVAP
FT                   LLSRSLILQLRPLNADDIRAVVQRAVDDPRGLGGQIAVAPEAVDLLVRLAAGDARRVLT
FT                   ALEVAAEAVQTGDELTVATIEQSLDNAAVRYDRDGDQHYDIVSAFIKSVRGSDVDAALH
FT                   YLARMLIAGEDPRFIARRLLILASEDIGLADSTALPLAVAAAQTVQLIGMPEAQLALAH
FT                   ATIHLATAPKSNAVMTALGSAIDDIKAGKAGLVPAHLRDGHYSGAAALGNAKGYKYSHD
FT                   DPDGVVAQQYPPYELVEVDYYRPTGRGGERELVGRLDRLRAIIRGRRG"
FT   misc_feature    35776..35799
FT                   /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
FT   misc_feature    36701..36705
FT                   /note="conflict: ACCTG is ATCCTCG in EMBL:MLB937CS"
FT   CDS             complement(37086..37599)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1259.28c, probable pseudogene, equivalent to
FT                   M.tuberculosis hypothetical protein Y0AA_MYCTU MTCY9C4.10c
FT                   (236 aa)"
FT   CDS             37990..>38807
FT                   /transl_table=11
FT                   /gene="alaS"
FT                   /product="alanyl-tRNA synthetase"
FT                   /note="MLCB1259.29, alaS, alanyl-tRNA synthetase, partial
FT                   CDS, len: >272 aa; highly similar to many e.g. SYA_ECOLI
FT                   alanyl-tRNA synthetase (EC 6.1.1.7) (876 aa), fasta scores;
FT                   opt: 842 z-score: 921.6 E(): 0, 49.6% identity in 274 aa
FT                   overlap. Contains PS00339 Aminoacyl-transfer RNA
FT                   synthetases class-II signature 2"
FT                   /db_xref="GOA:O69491"
FT                   /db_xref="InterPro:IPR018165"
FT                   /db_xref="UniProtKB/TrEMBL:O69491"
FT                   /protein_id="CAA19104.1"
FT                   /translation="MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFV
FT                   PFFLGQCTPPYATATSIQKCIRTPDIDDVGITTRHNTFFQMAGNFSFGDYFKRGAIELA
FT                   WALLTNSFADGGYGLDPERLWATVYLDDDEAAGLWQEIAGLPPERIQRRGMADNYWSMG
FT                   IPGPCGPSSEIYYDRGPEFGPEGGPIVNEDRYLEVWNLVFMQNERGEGTTKEDYEIRGP
FT                   LPRKNIDTGMGVERIALVLQGVHNVYEIDLLRPVIDLVATRAPRPYDPEN"
FT   misc_feature    38680..38709
FT                   /note="PS00339 Aminoacyl-transfer RNA synthetases class-II
FT                   signature 2"
XX
SQ   Sequence 38807 BP; 7460 A; 10643 C; 11908 G; 8796 T; 0 other;
     cgctggcttc ggtgttgctc gatgctaacc aaagggtctg cttggcgtcg ccctaggcgc        60
     tgatggtgtt taggagccac tacctccttg gccttcgccg ccacggtact aagtacccgg       120
     agtgcccttg acaagagtct ctcggctgcc tcaacctggg caggctgaaa cgtccaaaac       180
     ggtactcagg ctggcgatcg acccgcctgt cttcaaacca gcccgagcag ctgcagatcg       240
     ctgacatatt tggcgatgat tgccggcgag atatgcggaa tatctttgtc ctgaccaatg       300
     ttcgcgtttt gaacggccgt acggaaccgg attgtgggtg ccagcgaccc gtgcaatggc       360
     ttctccggct tctggtagtt gtgcaacaac ggcaacagtg agctgtgacg ctgcctttcg       420
     ggcagggcgc gcagcgaaat ctcaaaccgt cgcagccatt cgtcgtagtc gttgatgcgt       480
     tgtatagggc agccggcatc aattaaccag tccacaaact cgtccatacc gatgccgtcg       540
     tcgtgcgggt tcattacatg ataggtcgtg aacccgtctc gatcgtgcag gctttggtct       600
     cccagggtgg agatcgcttc ggcgatgaac tcgacgggca gaccgtcgta gtgggcgcgt       660
     tgccgattgc tctcggcgtc tagctcgtag aacgagccgg gtgcgatgcc ggtggcggct       720
     agactcagca tcattcgagt aaacatgtcg gggacgttga gctgaccggc atagctggtg       780
     tcggccaaga tcatgtcgca gcggaagacc gtgaccggca gaccgcatag gtcgtgagct       840
     tcgcgcagca gcacttcgcc ggcccacttg ctgttgccgt agccgttggc atagttgttg       900
     ttgatgttgc gcgtcgggct aatgactcgg atgtcggagt cttcggtgaa ttttgctggc       960
     tcaatctgat taccgacgcc gattgtcgac acatagatgt acggcttttg cttactggtc      1020
     agcgcgatcc gaatcagctc ggcggtgcct aacgtattgg ggccgaatag ctcgctgtac      1080
     ggcagcacgt ggttgaccag ggcggcgggg tcgacgatca gatcgaccgt gtcggccagt      1140
     cgtcgccacg tttgccggtc caattccaga tctacttcgc ctttgtcgcc ggcgatgacc      1200
     tccaggtggt cggttgccag ttcctggtag tgcgccagca gtttggggtc tccgctatcg      1260
     aaggtcttgt cgagccgggc ccgagcgtcc tcgttggact tggctcttac cagagcgatt      1320
     accttccctt cgaccaggtc catccgttcg agccatttca gggccaagta gcgccccagg      1380
     aagccggtag cgccggtcaa caggacggtg cgcacctcgg tgccgggttg cgccaatacg      1440
     ggcgcggcag tcagcgttga tacatcgatg aatttgtcta gagtgaggtc actggcatgc      1500
     actttgccag cgtcacgacc gtgtatggca atgaaagtgg gccgcttcgt gccctgccgc      1560
     tcgcgctcga tgtagtcggc gatcgccacc aagttgttga cagggctgac aatgacgccc      1620
     accggcacat cgatgtcgaa gagttcgcgt agcaggctac cgaatgtcag cgcggacaac      1680
     gagtctcctc ctaagtcggt gaagtgcgca ttcgacggca aatcggtggt cgccactccc      1740
     agaatggtgc ccacggctcg gctcaccgtc tgcagtaccg gagcgttcgc cacgctttgt      1800
     tttagcacgt gcagtgcatt tgcctgacct tcaaccagat cggcgtagag ctgttcgagt      1860
     cgcgcgccgt agtgctgctt gagcttcggc cacgccagct tgcgaatacc ggtgagcagg      1920
     ccattctcca ggctgaacgg tgtagtctcg acgattaagt cgcgcggcac ctcgtaggac      1980
     tgcaggtcgg cttctttcgc tactttctgt aaagaatcga taatcagcgg tttgagcacc      2040
     tcaatgtcat tggtagccaa cgcatcctcg gtcggcacca caacagccaa caggtagggg      2100
     tgtgcgctgt tgccatagat gtagatctgc cggaccagtg ggctattgct gaacgctgcc      2160
     tcgagtttcg cgacggtgac gaactggccc tgcgcgagtt tcagcacgtt gttgcggcga      2220
     tcgacgtaca cgagccggtc gggaccgact tcggcgacaa tgtctccggt ctggtagtaa      2280
     ccgtcgctgt cgaacacggt ggcggtaacc tcaggacgct tgtagtagcc ggggaacatg      2340
     ttctgggtct tgagcagcaa ttcacctctc ggataaggct ggtcggtgct gaagtagccc      2400
     aaatccggaa cgtcgaccag cttgtaatcg ataaccggcg gacgttgcac ttcgccgtca      2460
     aacaagacca tgccggcttc ggtggagccg tagccttcca acagatgcat ttcgagtagg      2520
     gactcgaccc cgtgtttcaa ctccggggag gttggcgccg agcccgtcat agccgcgatg      2580
     taccgtcctc ccagcaggga ttgccgctgt tcatccataa cttcggcttt gatggctgca      2640
     cggtcggcgg agccgctgtt ggctaaccga cggtcaactg cgcgtttgga ttcatcgtag      2700
     agggtttccc agatgcgcgg tacaaagttc aactcggtcg gccgcaccag cttgagatcc      2760
     tccagcagcg tcgagaggtc gctgcgggcg gcgaagtaag ccgtgccgcc gttaccgagc      2820
     gtgccgtaga ggattccgcg gcccatgacg tggctcatcg gcatgaagtt aagagtgatt      2880
     gacgcggcgg ttggcccgaa ccagtttccg tctgaccggc gccacatctt gccgacattg      2940
     ctttgcagat acatcgcgcc cttgggtgcg ccggtgctgc cagatgtgta gatcagcaac      3000
     gccaacgggt cagcagagtc atcggccacg gggatcggcg tagctggcag cgtcttgccg      3060
     cgaccgagga cctcggtcag gctctcgacc accacgctac tgtccgccaa ccgcgcccgg      3120
     gcggttgcca ctgcgtcatg ctgctcgtcg acctcggggt ggtagtcaaa cacaacgagc      3180
     ttcgctggcg cctggccaga caggatcagc tcgacagtat cgggcagctg gtttacgctc      3240
     gtcgcgatca tactgggttc ggtctcggtc acgatcgact gcagctgggt gatcgccgca      3300
     ctggtctgca gtggaaccgc cacagcacca atcacgccga gcgccatgtc gatgatggcg      3360
     taatcgacac tgttgaaacc tagcacgcag acccggtagc cggcgtgcag taggtcgtgc      3420
     ctccaggcgc gcgccagcgc tccgacacgg tcgcccaact ggcggtaggt gatggtctca      3480
     aagctgggga gcagctccat cgaggtgcgt ccggtcttag ggtctttggt gaactcggcg      3540
     acgcgctggc ccagtgccgg ccgctccgcg taaccgtcca gcgcggtctg gatgatttgg      3600
     ggcagtcgaa gcccgggctg ggcaagggcg gcggctaccg ccgggtcggg tttggcggcg      3660
     gcgaactgcg ggtcgttggc ggtgaggtcg tcaacgcggc gtgcgagctg cttttcctgc      3720
     ttagtgatag tcgacataac agattccttg cgatgagaaa tagactgttg gcgccacacg      3780
     gcacagacaa ttagaaaatt agctgtgcta aaatattcct cagtggctgg gttacagatg      3840
     tgagatcgtc cacttcaggg gttcttggtc tagtctagaa gtcacccagg atccggctta      3900
     ggatgtcaag gccttcggcc aacagttcgt cgcttatggt cagaggcggc agcagtcgga      3960
     tgatgttgcc gaacatgcca cacgtcaaga tgatgacgcc ggtagcgtgt gctgcggtgg      4020
     ctactttttc ggtcagctcg gggtcgggct cagccgtgcc ggattttacc aattcgacgg      4080
     cgatcatggc accccggcca cgtacgtcac ctatccgatc gtcggcgtcc tgaagtcgca      4140
     acaaccggtc ggtgatcagc cgttcgatct gttgggctcg ctggatcagg ccgtcgttct      4200
     cgatggtcgt gatggttgcc aaagccgccg cgcaggcgac cgggttgccg ccgaaagtgc      4260
     caccgaggcc gctgacgtgc ggggcgttca tgatctcagc ccgtccggtt accgccgcca      4320
     gcggcaatcc gtcggcgatg cccttggcgg tgcagatcag gtcgggcacg attccatcgt      4380
     gctcgcaggc gaacatggcg ccggtacgcg caaaccccgt ttgcacctca tcggcgatga      4440
     acatcacgtt gttcttgcgg caccaatcca gcaaagtagc taaaaaccct tcggccggga      4500
     cgatgaaacc gccttcgccc tggatcggct caatgatcac ggcagccagg tcatcggcgc      4560
     caacctgctt ctcaatgacg ttgatggccc gtgcgccggc caacttgccg tcggtggcta      4620
     ggtctttgtt gagcaggccg tcccgatagg ggtaggacag cggcgcccgg tagatctccg      4680
     gcgcaaaagg accaaagccg cttttgtacg gcatggactt ggcggtcagt gccattgtca      4740
     ggttggtgcg accgtggtag gcgtggtcga acgcgaccac tgcgggcttg cgggtgtacg      4800
     aacgtgcgac cttgatagaa ttctccactg cctcggcgcc ggaattgaac agcaccgagc      4860
     gtttctcgcc ggatcctggg gtaattcgat tgagttgctc ggtgacggcg acgtactcct      4920
     cgtaaggtgt gattatgaaa caggtgtggg taaagtcggc cacctgggcg cgcaccgcgt      4980
     ccacaacgcg aggcgacgag ttgccgattg tggtgacggc gattccagaa cccaggtcga      5040
     taagccggtt cccgtcgacg tcctcgataa cgccgccggc ggcgcgcgtt acaaacactg      5100
     gcagggtgac tcccacccca cgaggcaccg ccgcgttgag gcgtttggct agttcaagtg      5160
     acacggggcc ggggatttca gtgaccagct gacggctctg ctcgacgctg gtcacgtgga      5220
     tcctcctgac tacgacacgc cggttgtatc gcagataaag catagccttt atcggggttc      5280
     tcacaccggg cgagtgtggc taggccacgt ctctgggcga cagtgtgcgc actgtgccgg      5340
     gttgggtgcg acttgggacc tgccagagta gatgagcaca aactgaacgg ttattttggt      5400
     gcgcgtccgc cggtcagctg gccagcgttg cgcccagtac caaataaaaa atacatacaa      5460
     aatacaggtg ggttgatggg tcgatggaga gtttggtttt actcttactg ttcctgctca      5520
     tcatgggtgg gttcatgttt ttcgcgtcgc ggcgtcaaag acgctcgatg caagccacga      5580
     tcgacctgta caactcgcta cagccaggcg accgagtgaa taccacctcc ggcctgcagg      5640
     ccaccatcat tgtcgtcggg gacgataccg tcgatcttga gattgcgcca ggcgtcgtaa      5700
     ctacttggat gaagctggcg attcgtgatc ggattctccc ggacgatgcg tatatggacg      5760
     aacacgaggc cgaaccgggg gatttcgtgt actgcgatga gctagaagag tccgacggct      5820
     ccagctaacg tcgaggaacg agtgatgagg gattcctgac ggcgcttgtg tcttgtgtga      5880
     agggcctagt gatgcgacac gtaggctctg tcgggaaaaa ccgatttcga ggagatacaa      5940
     ggaacgtggc atcgtcttcg gcgccagtgc attttggccg ctacctgtcg atgtttctgg      6000
     tgttattcat cggggtctat ctgttagcgt ttctcaccgg agacaagcgg gtcgttccca      6060
     ggctcggcat agacctccaa ggcggcaccc gcgtaacgtt gaccgcgcgc acgcccgacg      6120
     gctcgcgccc cagccgggag gcgttgtcac aggcgcagca gatcatcagc tcccgggtta      6180
     acgggctcgg agtatcgggt tcggaagtgg tcgtcgatgg cgacaacctg gtcatcactg      6240
     tgcccggcaa cgacggcaac gaggcccgca acctgggcca gactgcgcgt ctgtacatcc      6300
     ggccggtgct taactcgcta cccgtgcaac gtggtcaaga ccccaagccg ggttcccctg      6360
     ccggcacgtt gcccaatttc gcgccgatgc cgcccgacca cccaggcgcg caaccacgcc      6420
     cctacctgca agatccgacg tcatcaccta gctcagatcc gatgccaagt ccagtgccaa      6480
     ccggagcggc actaccgggt gaggttccct cggttgagca gcccgcgcca ccggatccgc      6540
     gtaaggatct agctgaacgc attgccgagg agaagaagtg gcggcaaagc accaaacaga      6600
     gtattcagtt cctcgcattg cagttcgaat ccacccactg cgacaaagac gacattctgg      6660
     ccggcaatga cgacccgaat ctgcctctgg cgacctgctc gaccgaccat aatatggcgt      6720
     atttgttagc gccatcgatc atcagcggcg accagatcca aaactccacg tccggcatga      6780
     accagcgtgg ggtcggctac gtcgtcgatc tgcagttcaa gtctgcggcc gcagatgtct      6840
     gggctgactt caccgccgcc cacatcggta ctcagaccgc tttcaccctg gactccgagg      6900
     tggtcagcgt cccggtaatc aacgaggcaa ttttgggcgg gcgtacccag atcagtggtg      6960
     gagatccgcc gttcaccgcc gcaaccgcgc gccagctggc caacgttttg aaatacggat      7020
     cgctgccgct atctttcgag ccgtcggaag ctcaaacagt ttcggcgact ttggggttga      7080
     catcgttacg ggcgggtctg atcgcaggtg cgatcggcct gagcctagtg ttgctgtact      7140
     cgttgctata ttaccgggta cttggattgc tcaccgcgtt ttcgcttttc tgttccggca      7200
     caataatttt tgcgatcttg gtgctcttgg gtcgatatat caattatact ttggaccttg      7260
     cgggtatcgc gggtctgatc atcggtatcg gcaccactgc cgactccttc gtggtgtttt      7320
     tcgagcggat caaagatgag atccgcgaag gccgttcgtt ccggtcggct gttcctcgtg      7380
     gctgggtgcg tgcccgcaag acgatcgtgt ccggcaacgc tgtcaccttc ctggcggctg      7440
     ctgtgctgca cttcctggcg attggccaag taaagggatt tgctttcacc ctcggcctta      7500
     ccacgatcct ggacctggtg gtggtgttcc tggtgacctg gccgctggtg tacttggctt      7560
     ccaagtctcc gttgctggca aggccggcat acaacggctt gggcgccgtt caacaggttg      7620
     cccgcgaacg acgggcttcc gccaagacag gacgggggta gcgcgatggt ctccagagcc      7680
     aaagtcggcg ccgagaccac caagggtatc gacgaaccag accgaaatga caacaccgac      7740
     gacaatggcg ccggtgcggt cgaagtcacc gaagccgccg aggatgccgt ggagctgact      7800
     aacgatatat ccacacagct gccgcagcac ggctttcttg ctcggttcta caccggcctt      7860
     tctcgactgt acaccggcac cggtgtgttc gaggtggtgg gacgccggcg gctgtggtac      7920
     agcgtgggcg gcgtcatcgt ggcggttgcg gtcctgtcca ttatcgttcg cgggtttact      7980
     ttcgggattg atttcaaggg cggcaccacg gtgtccatgc ctgtctcgcc cggagtgggg      8040
     gggacaggcg caattgaggt tgcgcaggtt gccgatgtct tcaagaagac ccttggcagt      8100
     gatccggaat cggtggtcgt tgttggtaac ggcgcgtcag caacggtgcg gatcagttcg      8160
     aaaacgctgt ccaatgacca gacgtcgaag ctgcgtaacg ccttgtttga cgcattcgga      8220
     cccaaaggcg ccgacgctaa gcctagcaag caggcaatca gcgacgcggc ggtatcggag      8280
     acctggggcg gtcagatcac caagaaggtg gtgatcgctc ttgtggtgtt tctggtgcta      8340
     gtcggcctgt acatcactgt gcggtacgag cgttatatgg ctatctccgc actgactacc      8400
     atgtgttttg acctgaccgt cacagccggc gtgtactcgc tggtgggctt cgaagtcact      8460
     ccggccactg tcatcggctt gttgacgatc ctcggtttct ctctctacga caccgttatc      8520
     gtgttcgaca aagttgagga gaatacccac ggtttccagc acaccactcg gcgcaccttc      8580
     gctgagcagg ctaacttggc gatcaatcag accttcatgc gttcgatcaa caccagcctg      8640
     atctcggtac taccggtgtt ggcgctgatg gtggtcgcgg tgtggttgct gggcgtcggt      8700
     acgctcaagg acctggcatt agtgcagctg gtcggcatca ttgtcggcac ctactcgtcg      8760
     atcttctttg caactccact gttggtcacg ctgcgtgaac gcacagagct ggtacgcacc      8820
     cacacccgcc gggtagtcaa acggcgcacc ctcggttcgc aagtgggcaa aaaaaacgct      8880
     gacagccacg ttgcagcagg cacccgaaaa ccgcagaatc aagcggaatc ctgcgctgac      8940
     gcatcgtcgc aggagggcac cgaggtcgcc accgcgtccg tgcccacggt actcagcaag      9000
     ctggcaccgg gagtgcgtcc ggtgcggccg accggtaccc gacgtcctac cggcaagcga      9060
     aacaacgtcg gtcggcggta gtcaaggtgg ctacccgagg ttggcaagcc gtgagtgagt      9120
     acgattgcgg tccggcttat tcggggtttt gcggtggact gcagtaggct tggtcgcgac      9180
     gctggtggct tctttggcgc tgactgcgtg ttctggaagc gccgcggggg agatcgtcta      9240
     tgtggtcgac ggggcgttgg gtacctacaa cactaacacc atcgtcggtg ctgcgtcggc      9300
     cggagcgcag gcgtttgccc gcacgctcat cggcttcggc tatcacggcc ccgatggaca      9360
     gatagtcgct gaccacgact tcggaaccat cacggtggtg ggcggggtgc cattagtgct      9420
     cgactaccag atagccgaca atgctgtcta ctccgacggc aagcaggtga cttgcgatga      9480
     tttggtgctg acctgggctg cccagtctgg gcggtttccc ggcttcgatg ctgccaccca      9540
     ggccggttac cgcgacattg ctaatatcga gtgcctggcc gggcagaaga aatcccgcgt      9600
     gttcttcgtc ccggaccgca gcgttgtcga ttatgaacag ctgttcgccg cgacctcgat      9660
     gatgccgtca cacgtcatcg ctgaccaact gaatatcgac gtgacggagg cattgctgac      9720
     ccacaatgcg acattggtgg aacagatcgc gcgattgtgg aacaccacct gggacctcaa      9780
     accagctgtc gatttgagac gcttcccgtc gtcaggccca tacaagatcg aatccgtctt      9840
     gaacggtggc gctgtagtgc ttgtagccaa cgaccgttgg tggggtctca aggcgaccac      9900
     caagcggatc acagtacggc cacaggaagc cgacatccag gaccgagtca acaaccgcag      9960
     cgtcgacgtc gtcgatgtcg cggtcgggtc gtcgggatcg ctggccactc cggacaatta     10020
     cgcgcgcatc gactcgccgt cggcgggcat cgagcagctg atctttgcgc cgcaggggct     10080
     gctggctgcg gctgccgccc gccgcgcact cgcgctgtgt acgccccgcg acgtggtcgc     10140
     tcgagacgcg gggttgtcga tcgccaactc acgcctgtcc ccggctaccg aggatgccat     10200
     cgctgcggcc gacggtgctc gcgaggccgg ccagttcagc aaggcggatc ccgccgcagc     10260
     gcacgacgca cttagtggtg agacgttgcc ggtgcggatc ggctaccaag ggcccaacgc     10320
     acggttggcg gccaccgtcg ggactatcgc caaggcgtgc gctgtagctg gtatcagtgt     10380
     gtccagcgtt accttggact cctcgacgga cccctcgggc ccgcaggcgc ttcgggacgg     10440
     aaagatcgac gtgctgttgg ccagcactgg tggcgccacc ggcagcggat cgagtgggtc     10500
     atcttcgatg gatgcctatg acctacacac cggcaacggc aacaacctgt ctggctatgc     10560
     aaacgcgcag gttgacaaca atatcggcgc gttggcggta tccgctgacc cagccgagcg     10620
     tgttcggctc ctcgccgata gtgcacctgt actctgggcg gatatgccga cattgcctct     10680
     ataccggcag cagcgaatgc tgctgatgtc gaagacaatg tatgcagtta ccaggaatcc     10740
     gacccgttgg ggcgcgggtt ggaacatgga tcgatgggcg ttagtacgat gaaaagcttt     10800
     aaggtttgag gaggtgtctc cgtggccgac cttatcgctg ccttgactcg gaatgcggcc     10860
     gatttcccga cgccagccat ccagttcaag gaccttactc cgctgttcgc tgactgacag     10920
     gcgatggcca gcggtgatcg atgcgttagc agacgttgca gctggcgctg atctggtcac     10980
     cggcctcgag tttcgaggga ctatggtggt tgcagctaca gcggcccggc tcgacatcgg     11040
     tgtattggcc attcgcaaga gcggcaagct gccgctgtct gtgctcagcg aagattacat     11100
     catggagtaa cggccagcgg catcatcgag gtacccgctg acagcgtcga gctacgcagc     11160
     cgcaacgtgg tgattattga cgacgtcttg gcgactgccg gcactctcgg tgtggtgtgc     11220
     cgattattgg agcgcagcgg gtccggtgcc attgcggcgg cggtaggtta tggaactcac     11280
     ggcgttgggt ggtcgcgagg cgatcgcacc gctgcaggta caaagtttga gccgcgccta     11340
     gcctcgctat ctgggtactt cccctccgtg ctggaatggc ttgggagaag caggtcaatc     11400
     ggactcaggg atatccttaa ggtcggaggt gaccaacgtg gcggacgacc aaggtacggc     11460
     gcaagctttg caaccagttc aggtggtccc cggccctgct gttgaggcac cggagacgcc     11520
     ggtcgaaacc ctgaagactt ctagcagtgc gtctcgtcgg gtccgggctc ggttggcccg     11580
     tcggatgacc gctcaacgca gcaccatcag tcccgtgctc gagccgctgg tggctgtgca     11640
     taaagagttt tatcccaagg caaacctttc gatagtgcag cgagcctttg aagtcgccga     11700
     ccaacggcac gccagtcaac tgcggcgttc cggtgatccg tacatcaccc atccgctggc     11760
     cgttgccaac attttggctg agttgggcat ggatatcact accctggtgg ctgcgctact     11820
     gcacgacacg gtcgaggaca ccggttacac gctcgaggca ctgtccgaag aatttggcga     11880
     cgaggtaggc catctcgtcg acggggtgac caagctggat cgggtggtgc tgggcagtgc     11940
     tgccgagggc gagaccatcc gcaagatgat taccgcaatg gcccgtgatc cacgggtgtt     12000
     ggttatcaag gtggccgacc ggttgcataa catgcgcacc atgcgcttcc tgcctccgga     12060
     aaagcaggcg cgcaaggccc gtgagacatt ggaagtcatt gcaccactag cgcataggct     12120
     aggtatggcc agtgttaagt gggagttgga agacctgtct ttcgcgatct tgcatcccaa     12180
     aaaatacgag gagatcgtac ggctggtagc gggccgtgca ccgtcccgcg atacctacct     12240
     ggccaaggtc cgtgccgaga tcataagtac cctgggtgcg tcgaaaatca aggcgacggt     12300
     ggagggccgg cccaagcatt actggtcgat ttatcagaaa atgatcgtca aggggcgaga     12360
     cttcgacgat attcacgact tggtcggcat ccgtatcctg tgcgacgaga tccgcgactg     12420
     ctatgccgct gtcggcgtgg tgcattcgtt gtggcagccg atggcgggac ggtttaaaga     12480
     ctacattgct cagccgaggt atggtgtgta ccagtcgttg cacaccacgg tcgttgggcc     12540
     cgagggcaag cctttggaag tacagattcg tacccgcgat atgcaccgta ccgccgaata     12600
     cggcatagca gcgcactggc gctataaaga agccaagggc cgcaacggtg ttctgcatcc     12660
     acatgcagcc gcagagatcg acgatatggc ctggatgcgg cagcttctcg actggcaacg     12720
     agaggccgcc gaaccaggtg agttcttgga gtcgttgcgt tacgaccttg cagtgcaaga     12780
     gatttttgtg ttcactccta aaggggacgt catcacgttg ccgactgggt caacgccggt     12840
     ggactttgcc tatgcggtgc acaccgaggt cgggcaccga tgcattggtg ccagagtcaa     12900
     cggacgactg gtggcgctgg agcgcaagct ggaaaacggg gaattcgtag agattttcac     12960
     atccaaagct cccaatgccg ggccttcgcg ggattggcag cagttcgtgg tgtcgccgcg     13020
     cgctaagacg aagatccgtc aatggttcgc caaggagcgg cgtgaggaag cactggaggc     13080
     tggtaaggat gcgatggccc gcgaggtacg tcgcggtgga cttcctttgc agcgcttggt     13140
     gaatggtgag tccatggcgg cagtggcccg tgagctacat tacattgacg tgtccgcact     13200
     gtataccgca attggtgaag gacacgtgtc tgcccggcac gtcgtgcagc ggctgttggc     13260
     cgagttgggc ggtatcgatc aggctgaaga ggaactggcc gaacggtcca caccgacgac     13320
     catgctgcgc cgtcaacgca gcaccgatga tgtcggggtt tcggtccccg gcgccccagg     13380
     tgtgctgact aagctagcca aatgctgcac gccggtacct ggcgatgcga tcatggggtt     13440
     cgttacccgc ggcggcgggg ttagtgtgca ccgcaccgac tgcaccaaca cggcatcgct     13500
     gcagcagcag gccgagcgca tcatcgaggt gttgtgggcg ccgtcgtcgt cgtcggtgtt     13560
     tctggtggcg attcaggtgg aggcgctcga ccggcatcgg ctgctgttgg acataacacg     13620
     cgcgttagcc gacgaaaggg tggacattct atcggcgtcg gtcaccacgt cgggtgaccg     13680
     ggtggcgatc agccggttta ccttcgagat gggtgacccc aagcacctcg gacatctgct     13740
     caatgtggtc cgcaatgtcg aaggcgttta cgatgtctat cgggtgatgt ctgcgtcttg     13800
     acgttcgggt ggttactcgg caaatccccc tctgctttga cgtggatgac cggacggctt     13860
     tagtcgagcc gcagcgactc gatggtaact tcggtggctg gtggcccgtc atcaccgccg     13920
     ctggcgattc cgcccttagc tatcttgtcc agcgtggcca gcccgtcagc ctggatcgtg     13980
     ccgaagacgg tgtactcagg cggtaactgt gagtcatggt agactagaaa aaattggctg     14040
     ccattggtgt tcggaccgct attggccatt gccagtgtgc cacgcggata cagaacaggt     14100
     tgcttcaatt tagggtcgtt gggcgggtac tgatctgtgg ggtactcgtt agcgaacttg     14160
     tatcctgggc cgccggtgcc gtcgactttc gggtcgccac actgtaagac gcccagcatc     14220
     agggaagtgg tcaacctatg acattttgtg ttgttgaaaa agccctggcc ggttagactg     14280
     gcgaaactat ttaccgtgca aggtgattcg gcattgttta gcaatagacc gatattgccc     14340
     tggttggtag ccatacttgc gctcactgtg gctggatcgg tcggcacctt gccggcccgt     14400
     ggcggcttga ctggcttggc ggccttgtcc gctgatggtg ggtactggca gttgacgccc     14460
     aggttggtcg acggttggaa tgatggcaat ggcagaactg acggcgtaac ggcgggagtc     14520
     ttagtcgctg tcagggagtt actggcggtc gacgaagcgg tatcgtgctt gtggccaagc     14580
     ttgctgatca cgacggtagc cactaccgta ataattacgg ccactgccac taccacgcca     14640
     ccgcttatca acaggactcg gcgccatcgg gcctgcttag cgcggcgctc cagctgtcgt     14700
     ttcagtttgc gcttggctgt tgcgcgtcgc tgttcgttgg tcggcacgtc cggtatgcct     14760
     ccatggttgt tcgattaatt ggggccgagt tgccagccaa ggctaatgtg aacgcctcga     14820
     cctgtgtcaa gtttttgttt cgcggcgtct gtctcggctg ctgagtggac cgcattgtcg     14880
     tcgacggcta agggatggga aactgggggt gtgttaatca ccggatttcc cgccgggatg     14940
     ctgcagtgca actgttacgt gctggccgac cgggcgggta cggatgccgt catagtggac     15000
     cccggccagc gtgcgatggg cccgctgcgg cgcatccttg acgagaatcg tttgactcca     15060
     tcggcggtgc tgctcaccca cggccacatc gatcacatgt ggtcggccca gaaagtgtcc     15120
     gacacctatg gttgtccgac gtacattcat cccgaggacc ggttcatgtt gaccgatccg     15180
     ctcttcggct tcggtccgcg ggtggcgcag gtcgtcacgg gagcgttctt tcgtgagccc     15240
     aagcaggtcg tcgagctgga ccgggatggc gataagctcg atttgggcag tgtgaccgtc     15300
     aacgtcgacc atacccccgg acatacccgc ggctcggtgt gtttttgggt cgccgcagat     15360
     accgacgtgg tgttgaccgg cgacacgctg ttcgagcgca ccatcggtcg caccgatctg     15420
     tttggtggca gtggtcgtga cctataccgt tccatcgtcg aaaaattgtt ggtactcgac     15480
     gacaagaccg tggtactacc cgggcatggc aactccacca ccatcggtgc cgagcgtcgt     15540
     ttcaatccgt tcctcgaggg cctgtagctt gtgacggagt catgcactgt gttttcgttt     15600
     tctgggccca aggggatacc ggattatttt cctccggact cggcgcaatt tgtcgcggta     15660
     cgtgatggtt tgctcactgc cgcccgcagg gccggttacg gcgatatcga gttacctgtt     15720
     ttcgaggaca ccgcgttgtt cgctcgcggc gttggtgagt ccactgacgt ggtagccaag     15780
     gagatgtata cgtttgctga ccgtggtgat cgctcggtta cgctgcgtcc cgagggcacc     15840
     gctggggtgg tgcgtgcggt gattgaacac ggtctggacc gtggagcgtt gccggtgaag     15900
     ctgtgctacg cgggcccgtt tttccgatac gagcgtcccc aggccggccg atgtcgccaa     15960
     ctgcagcagg tcggcgttga agcaatcggt gtcgacgacc cggccctaga cgccgaggtg     16020
     atcaccatcg ccgacgctgg cttccgctcc ctgggtctgg acgggttcca gttggaaatc     16080
     acttcgctgg gcgatggtac ttgtcgcccg caatatcgaa aactgttgca ggagtttctc     16140
     ttgcagctcg accttgacga agatacccgc cgacgcgccg agcttaatcc gctgcgggtg     16200
     cttgatgaca aacgacccca ggtgcaagcg atgacagccg cagctccggt gttgctagac     16260
     catttgtccg atggcgccaa gcagcacttc gatacggtgc tggctcacct ggacgctctg     16320
     cgggtgccat atgtcatcaa cccgcggatg gtgcgagggc tggattacta cacaaaaaca     16380
     accttcgagt tcgtccaccc cggcttaggt gcgcaatccg gcatcggcgg cggtggacgt     16440
     tatgatggtc taatgcgtca gctcggcggg caggacttgt cgggcatcgg attcggactc     16500
     ggggtggacc ggaccttgct ggccctacat gccgaaggca agaccgtggg ggaaaccaca     16560
     cgctgcgacg tattcggtgt gtcgctgggt gaagctgcta aactcaaggt ggcgatgttg     16620
     gccgggcaac tgcgtgctgc cggcgtccgc gtcgacctga tctacgggga tcgcgggatc     16680
     aggggagcga tgcgtgcggc gggccgttcc ggtgctcgca tcgcgttgat agtagatgat     16740
     tgcgccatta aggccgacgg tgtcggtgtg agggatctag ccaccggtga acagatttcg     16800
     gtagctgtag attctgttgt cgccgaagta atttcgagaa tagctccgag ttagctcggc     16860
     tgacttcgtc agacgaaatt tgtcgttcgt ctgaaccagg ggtcggcgtt attgaccata     16920
     cggttattga cgtgatcgca gaagccggct cgcggggatg ctgaggtgtt gggagcgaag     16980
     acatggcgtt tgttattgtg ctccctgaac tggtggcagc cacagcgacg gatctgtagg     17040
     gaatcggcac ttcgctgagc gaagtcgacg ccgcggctgc cgcgcaaaca actggagtac     17100
     tggcggccgg tgatgacgaa attcggcggc cactacgacg ttgtttccgg gtacggtctg     17160
     gcctaccggg cgctcagtga tcaggtggag caatttcatt aacaggttcg tgcaggcgct     17220
     caatgtcact gcgacgcgtt atgtcagtgc taggtcggta aatgcctcgc tattgcagac     17280
     tttggagcag gagctgttgg gtttggtcaa tgcgtccacc gagacgttgc tgggacatcc     17340
     gctgattggc aatggcggta tgaaaggcaa cggtggtcaa ttggcgggca cttcggggat     17400
     gatgggtgcg gtgcagccct tccgcgtgtg gacttgacga atattgggat tgatgttcgc     17460
     atataaacat gtgttgggct ggtcaaactt cgtagtcaac gggacgtttg tcgacgacgg     17520
     ggtgctgctg gcggctgcag cgggtcggtt tcgtccataa gcgtgcgcgt tccgcatttc     17580
     gagagccgct acgtattgat gcccggcatc atcaacacgc tcgtcggggt ccggcacgct     17640
     gctgtcaatc tttcgcccta cggaaccctg ctgggtaggg acctgtcgct catcgccgac     17700
     gaggtgcaac aggtgtcggc gtcgctggcg gtagctgatg cagagttaca ctgagatgtc     17760
     gaactgggca catcggatac cgcaggagct tctggggctg atcagcgcaa tccgttacgc     17820
     cggtctggac tggcatgtga tggttgttgg tttggccgta tctcaccgac tccatcgagc     17880
     accttgaccg gttgcttgga cgggaacgtg gctgccggtg tgaaggtttt cgtcctacat     17940
     ttgcgtggtt cgacccgcgg ctgattcata tcctggttgg cctgtgcgca ttctgaattc     18000
     gtcggcccgt accaggaatt ctaccagtgt agagcctatc tgccgctgag ctaccgtgag     18060
     atgtttcggc aacgtgctgc gctgctgatt acgaggtatc agctgatggg tgatcaccgc     18120
     cggtggccat tgacgaccat atcggcggcg gttccgggtc acacagcacc accggcacgc     18180
     cagtagcgaa ctggtctatt gcggtgatgg cgttgaacag cccgctcacc gcgtaatacg     18240
     ttgccttgat tgacatcata ttgtggactg gttgacccgg attgacgtag aaagccgtaa     18300
     ggattgttgc ggtcgtgaaa caccgaccgc gccgcatctg tataaaatgt atatcggcac     18360
     cttacgtccg atagcgggat caaatgtacc gacgtcggta agccacgcgg cactaagggc     18420
     actaaggttg gagggaacag cagcgcgttg ctgggcagcg gggtaccgcc gccgataacc     18480
     atgtgcactg tgccctgggt ggcgtcgatg aggtcgacgg gaattggtgt ttcgggtgtc     18540
     tgcacccaat attacgcgca atgggtgtga gcgttcggta atggtgttcg tggctgcgca     18600
     tcacgagatc gacctggtgc tcgtcgaaca acctcaacca ttcctcgcga aatcccgatg     18660
     tcgacgccat tgttgcggtc agtggtggag attgtcgcct gatgaataca aacgaccacc     18720
     cagtcaaaat ctgggtcgtt tcgtgcgtcg gctaatttgt ctgcaagtta gcgcttttgc     18780
     tttcctacct agtatttatg cacgtacgaa ttgcggccat cttgtaaggc cacgtcctcg     18840
     ttgttccggc tgattacccg cacagagtta gcggtgaatg agtagcatag agctgaggac     18900
     tagatcccaa attgttcacc gcaaagtaga tctcatagga accgtaacta attggcccat     18960
     tgcctaattc gctctcgtga ttgccgaagg ccggcatcaa cgacagttaa tgcgtcgaat     19020
     cgggtggtgt tgtcaagccg gcccaaccaa gtgcgggtcc ggtcttaggc gagttcagcc     19080
     tagcataggt caccgtgcac gaggttgaac agcagggcga tgcgtttgat cgcgatcgtg     19140
     gtatcgtcgg ctgtgggcga gccaatgttg ttgattaatg ctatgtatta ttggtcaact     19200
     ggcttaactc cggagtagat cgaccactga aactgtatta atagcagcca tttttcgtca     19260
     ttctggtgcg gtgtgcacgg tccttagccc gggctccata cctatgatgg accgcggcgt     19320
     agatgtagtc ggtgtccgcg gtcaggttcg tcaagtgggt gtggttggtg cggacctggg     19380
     tgtggactgt gcgtctcggt atgttcgggt ttatgttggc acggttttac cgagcccaga     19440
     tgtcggcgtg tcgaacatga ctcgcggtct gcggatggcg tcggtggtgt gccatgacac     19500
     gataacctcg gttgcggcgt ttttgccaaa ttgcagatgc agaccaccca ccggcggtgc     19560
     gctatgtcgg tccgaccggg gtatgtatcc gtgaccgcgt gggtgagatc acaacagtgc     19620
     agctctgccc gcaccaatga tcgccgctac cgtactcgcc gttaacctgc ggcggctgac     19680
     ggcggttctg atgttcgggt ggtcgggtca ggaccatcgt cccgttgcgg atctcgctta     19740
     ttcatgcttc ataccccgag ctgggcgacc gctgatgtat ctggccggtg aacgtctgcc     19800
     gggactgcta cgcgggtaac tgaatccggt aagtgttttt gtcatgatga acctgcgaaa     19860
     aatgatcagc gcggtcgcga tcacaacgtt tggggtggtg ccggaagtcg caacgactac     19920
     accgacggca cccgcagacc cagctggtct atactaacaa aataatcacc agtgatctga     19980
     tcgtcaatat ccactacatg aacaccgatc cgcccagtta agcggtcttt aacgctgact     20040
     cagcgaaata tctgaacact gtgtccaccc cagatctccg gtgttcagcc actgggctat     20100
     atcgcaatgt ggcaatccga actagtggac gattgttacc gttcagcggg tgggctgcgg     20160
     atcaatgttc aattgtatcg tgagatcgcg gtggacggtc aggtggtggt atcataaaac     20220
     ggtggcagcc gcgtctggtt cttgacggga cctttctact cggcacgtag ccaatagccg     20280
     ctagatgcga tcgtgagcct ggtaggtggt gatcttgccc tttttcctat tatggcctat     20340
     agtaatccgg acagcagcgg catcgatatg agcactgaat tactggtcag catgttcgag     20400
     tccatcgaca atatcagcat gctcaaagaa tccattcggt gaattgtacc ggatgctgcg     20460
     catcatcgaa ctcaatgtcg gacggctgcc cttctacagc ggtagtaacc tgctcgtgtt     20520
     cgacgcgctg aaggttggtg catccggttg gcgcaccgca cggccgcacc cactttgcgt     20580
     ccgccgccgt acatcgacct gtaaaacgca gtgcgcgtca gcggtctgga gaaagcatag     20640
     attctttacg acgacctcaa ggagcctctg cagttcataa tcacagtcgg gttggtcacc     20700
     accgtgaaag ccggtctcaa tttgctggga ttgttcgctg gagatccgcg tgtgtcgttg     20760
     ctgccgctcg attgaacaag gacatgccga gttgcgtaag ctgttcactg tcgcctgagt     20820
     cggcgttcaa cccagcacgg taggctgtga tcgggacgat tactagagga cgtcagagcg     20880
     aatgccatgc gcgacgacac ggaccaatat gtcgtgaatg atgttttgat tgtgggttcg     20940
     gagtaattga gctgcattac acacttcgtg tgtgctcctt tcctcctacc gtgatcggtt     21000
     ggccagtgta taatatgtcg tggctatccc aaattcgtgg cgtcgaaggt gttacacttc     21060
     ttcgggccac cgctctgatg ccccatggtg agccactttt gctgttgcgt ggaggaatcg     21120
     tgtgtccacg attctgggtt ggtatttctg gttgtggctt tctggatatg atcgtcgctc     21180
     actgaggacg cagccaagag ggcatcttgg atgtccttgt cgttcaacgg ctccagataa     21240
     ggcacaccag tgctgttctg cttgatcgtt gacgcctagt gtggctaaca caccgcctgc     21300
     aactcggtgt gcgcaccgtt gccgtgggcg ccctgctggg cgaggcggag cgccccctgc     21360
     cggtttgcag atgatggtcg tattcgtgag cgaccattta ttctccgcca agtgggttgc     21420
     cgctggaact gaatttgtct atcagtactt cgaggaagtc ggtgtcaaag tacgtcgcct     21480
     ggtccaccgg acagtagaat ggtctcactg cgcgagtggt cagtctgtgg ctgctgttta     21540
     tctggctgtt gaacaacctg tttgtgcgga cgggtgtagc tgcgcagcag ttgtttccat     21600
     acagtgtcca cggagttact ggtgactact tacccagcac tgcacgtatt tgttggcatc     21660
     gacctcgggt ttttccctgt tcaagtcgaa actgggcgct aagttatcgg tagtgtcgat     21720
     tcgccgctgg ctcagaatgc cgcccggatc catgcccagg aatatcgcca ccaccacgac     21780
     caaccgctcg ccgccagagg tcgacgtggt gttagtgttt atctgcgtac tctcgttgaa     21840
     gagcaacgta ctcttcgttg cgctttgacc cttgcatttc tgacccagcc tgcagtccag     21900
     ctttgcacac cgcagcccct ggcatgctag cattgctacc cgggtccgcc gctgaccgca     21960
     gccagcagcg gcaccacgac atcgctgatc ggggtcgcca gactgtgggc gcgtgccttg     22020
     cggatgatcg ccccgttgcg gatatcccat tccaaccgcc gatggctttc ccggtcggcc     22080
     aggatcagtg tgccccaggc cgcgatgcgg aaattggggt tttctgctac cccggcaacc     22140
     ggaatcacgc agtagctcag agagcgtctt agcctcgggt ttggtggtca atatacagag     22200
     tagcttttcg gcggaatacc agaaactccc cagaaccacg gctgacgacg ggcagagcgg     22260
     ctgcaacctg gtagacctgt gcaacaccgt tttgcggcac ggtgacaata gtgttctcgt     22320
     aacacaaccc agtcagccgc ccgtgagcat cattgttttg gatagatttg attgccagca     22380
     ccacaacgtc gaccgggcca ggttaccttc gccagaatcg gtgcgcacct tatctggtac     22440
     cacgatacga ttgtcgccgc cgggacgaat ttagatgctg tcgcgcggag tgttaccaca     22500
     taccaggact gaatgcctgg ccgcatgcaa tatgtgccga ctgtcgttcc gacagcgccg     22560
     ggtccgacca atgaaatctt ggttgtgggg ttggtagcga tacggctgaa agttgcacca     22620
     ccctctagac tgggcagtcg ttagttgtca actaaaacgg ggagtgtttg tgctgcgtag     22680
     ccacggcgct ggtgtgttac ggaaaagcga tgccgggcag caggtaacat tagctggctg     22740
     ggtgtctcgc cgtcgagacc acggcggcgt catcttcatt gatctgcgcg actcctcggg     22800
     catcacacag gcggtgtttc gcgagcctga cgtgttggcc caggcgcatc ggctgcgcgc     22860
     tgagttctgc atcgcggttt ccggcgtagt cgagattcgc cccgagggta acgccaatgc     22920
     cgagattccc accggcgata tcgaggtcaa cgccacttcg ctgaccgtgc tcggtgagag     22980
     tgcgccgcta ccattccaac tcgatgagcc tgcgggtgag gaattgcggt tgaagtaccg     23040
     ttacctcgac ctgcgccgcg acggtcctgg atcggcaatt cggttgcgtt ccaaggtgaa     23100
     tgccactgct cgtgcagtgc tggcgcgcca cgatttcgtt gagatcgaaa ccccgacgat     23160
     cacccgctca accccggagg gggcgcgcga ctttttagtt ccggcccggt tgcggccggg     23220
     cacgttctat gctctgccgc agagcccgca attgttcaaa cagttgctga tggtggccgg     23280
     gatggagcgt tattaccaga ttgcccactg ctaccgcgac gaggatttcc gtgccgaccg     23340
     ccagcccgaa ttcactcagc tcgacatgga gatgagcttc gtcgatgccg aggatgtcat     23400
     cgcgatctcc gaggaaatcc taaccgagct ctggatgctg ataggctacc acattccggc     23460
     gccgatcccg cggatcagct atgcggatgc tatgcgacgg ttcggctctg acaagcccga     23520
     cttgcggttc gggctggagc ttgttgaatg cacagagttc ttctgcgaca caacgttccg     23580
     tgtcttccag gcaccgtatg tcggtgcggt agtgatgccc ggcggtgctg cacagccgcg     23640
     gcgcacactg gacgagtggc aggactgggc caaacagcgc gggcatcgcg gcctggccta     23700
     cgtgctggtg accgatgacg gtacgctcgg cggaccggtg gccaagaact tcagcgatgc     23760
     cgaacgctct cgcctggcct cccacgtagg cgccgaaccc ggggactgca tcttcttttc     23820
     agcgggcccg gcgaagtcgt cgcgggcact gctgggggcc gcccgcggtg agatcgccaa     23880
     ccggctgggt ttgatcgacc ccgaggcctg ggcgttcgtc tgggtagtcg acccgccgct     23940
     tttcgaacgc gccgacgagg ccaccaaggt cggcgaaatg gcagtgggct ctggtgcgtg     24000
     gactgcggtg catcatgcct tcacatcgcc gaaaccggaa ttcgaggaca gcatagagtc     24060
     cgatcccggc agcgtgttgg ccgatgccta cgacatcgtt tgtaacggcc acgagattgg     24120
     tagcggctcg gttcgtatta accgccgtga tatccaggaa cgggtgtttg cggttatggg     24180
     attggaaaag gctgaggcgg aggagaaatt cgggttcctt ttggaggctt ttacgtttgg     24240
     tgcgcctccg cacggcggta tcgcctttgg ctgggatcgg accaatgcct tgctggccgg     24300
     gatggagtcg atacgtgagg tgattgcgtt ccccaagacc ggcggtggtg tcgacccgct     24360
     cactgatgcg ccggcttcga taaccgctca gcagcgcaag gaatccggaa tagacaccaa     24420
     gcccaaagag gttgagtagg catgacagaa tagtttccgg acgctgaaac ggtaaaggag     24480
     ttcaacaaaa ccatcgtcga cgagttccag gacaacggcg gcaaggtcgg tgggcaattc     24540
     gccaattcaa acttgcggct gctaacaacg accagcgcta aatctggcca acgccgggct     24600
     tcgccactga cctatttttc cgcagcgacg gcaagctgat caccatcgtg tcctttgtcg     24660
     gtgcctcggt tagtccggct tgggtgcaca acctggaggc caaccctacg ggaacacgtc     24720
     gagatcgggg ttcgaagcgt tcgacgtgat ggcgcgtgaa ttgtcttcta ctgagcgcga     24780
     acagatcttc cctaaagttc cctcccttct ccgcaacggg acaagtcaaa accagccggg     24840
     tgatcccgct gttagagctg cacctgatct agtagcaggt aatagaccga gtccccgtgt     24900
     ttgtcaaaaa ctcatgttct caaggcaatt aggagttttc actgagtagg actccaactc     24960
     tgcgcgtccc ttagcgtcca gcatcgccag ttgcggccgt ttgacgttgg aagccacacc     25020
     caccacccag catgtgttca ccggaaccga tctcagcggc gccgtgcact accagaccgc     25080
     cgctctcaat cactagttgg gaagccagct ttcgcaactc tgggttgtac ttcagtatgt     25140
     tttccgatgt acggggatcc ttctctagac accaacagta ccactggttc gctgtccact     25200
     atcaggagtc aacccgaatg ttgcatgatc tttggtcttg cgtggggtcg ctgcgtgaag     25260
     atcgtatttc gcgatttgtc cccgacagac cacacctggc atgtcgggcc acgtatactg     25320
     aatttctgaa tactatactc ccactgtttg taatggaatg ataggtatac tcatttggcg     25380
     atggtgtcta tctcgaatag atctaatttg tagtaattta tgtgtaattc acctcttaat     25440
     attgtgctat aattatagct tataagcccg gtaaacgtgt gtgggttcat taattactaa     25500
     agtagaatta atatgtcttt gtgagtgtag aggttggggt gttacaagta agtttctatg     25560
     taaagtgtga aaatttttga ttgtgaggtt gttgccgata acaaggtggc tctagcaaca     25620
     accgccatga atccttctgc tatcaattcg gaatcacaaa gggtgacacc gtatctggtt     25680
     cagttatgcg cagcaggatc gaaagactat ccttaggcgg tggtatgcgg tcctagaagc     25740
     cgataacgcc aagattttga gctaaaagaa ttgtatatag tctttacgag ccggaaggaa     25800
     taactaacaa aaagatgtat tctgaaccgt tactaccaaa ggtaaacttg ggcaacatgt     25860
     ataccggctt ggattcttac tcgctgatac tcgctgccca ggtgtggaag gcggtgggtt     25920
     aggagttgag ggccattaga ttgttgtcaa tcgaattcta ctccatatcg ctttggacca     25980
     ctggttgggt cgccgcggcg acacagaaaa ctgatgcggt caagctattt ctgaggtggc     26040
     tgaatgacct cggtgaggca gttctctgag attgaggaac aaacctaata gctatagtgc     26100
     cagattttcg cgatgcacat accgagatgg tgtattcggg gtggatcgcg attcaccgcg     26160
     cctggagagc gaatatggtc aataacagcg ggttcgtact atagtataga aatagagatc     26220
     gcggcacgtg gccgggagta tgcaaggtgc tgggttgaag acggttaggc gatgaataag     26280
     atataggcgt aggttgtcgt tatactgttg tcaaggttgc cttcgttgaa gtagccgccg     26340
     tcgatcacca acaacaccgg gttgatccag ctgatgccac ttcccgcaga accgcttagt     26400
     tcggttattc gttgtggggt ggtgttgggc cgatacgatt tgcagagttg tgtgcgtcta     26460
     gtccatggaa agattttgtt gtagttaggt gaggtagtcg ttgagcttgc aatgctggtc     26520
     ggggtcgttt aggtgtttag gtgatgtttt gttgtgttgg aggcacaaac tttacatcga     26580
     tgccggtgtg actggggggt gtgccgcgcc cgtgggggtc gaccgtatgt ctgtggccgt     26640
     attgaagtat ctgctggtgg tcagaggttg acgttactcc aagggcggtc acctcgcttg     26700
     tgttgggcgt gggctgcatg aggaacaact cgtcatcggt agataacggc gctggcatgg     26760
     cctaggagcc cgtcgagcga aaatgctggc gacggtggtg tgctcgggca gcaagaagcg     26820
     ttgcagggcc agtgggaggc gagggctagg ggagtggcat tagtaggcag cggttgctag     26880
     ccagaacagc agataggtgc cggtgtcatc atattggggt gaactctagt tcgtcaacaa     26940
     tgatcacctc agcgcgtagc aggatctcga gttcttgact caggcgagtg ttgtcgattg     27000
     cggttacgct gcccaggaac gcttgcgcac cctcgtcgag ggagcagcac tggctgtttc     27060
     cactgtgggg tttcgggcgc ggaccgcggc tgggtatagt tcggggcgca tcgtagtgct     27120
     tgtcgagaat tgacatcttc cccgagtgcg acgagttcgt gttcggccac ggtcgccttg     27180
     gtggccggct tcaccacata gtagcgcctc gtggtcgatg acgatggcca cgtttgcccc     27240
     gatcaatcgg ggttggtacc ggagtagcgg gccgagctgt actggatgtg ggagagtagg     27300
     tcgaccttac gggtgatcga cgccgcgccg acctcgaatc acaacgacgg cagcgccgcc     27360
     agcagcttgc gctcggtcgc aaggcgctca ttatttatag gaatttatta ggtgacgatc     27420
     taccgagtgt atcgcggcgt tgacctccgt tcaccacgcc gcagcggcag cgttgccctc     27480
     agagatgctc accggttgta tggtgacctt ggcctaggtc aaagaagctg catcaataag     27540
     tcggactgcg gagtaaccgc acaggtgcta cacaatgtcc cgcgatgtcg gatagttggc     27600
     ctggcaccaa tccgggcgaa acccgtaata ggtggcaaat cagacatatt gggttgtgga     27660
     gacgactatg ctggcgacta cccggccctt caaacagctt atccgatcgg ccagtacgtg     27720
     cgtcgggacc ctgccgatcg cggcgagcac ctcggcggtc atcgccagca tggtggtagc     27780
     attttggtcg gagaaaaacg cacgattctc caccacgaga acgccagcac cgcgtagaac     27840
     ataaacaacc ctggtgcagg ttcggcccag tcgattagca gatactcact agctgtccgc     27900
     gcagcctgac tgcgatccgc actattgtcc ttacaccaca aagttttctg ctaggagact     27960
     aggcggcgga aattgcacgc caaaccttta tagccggtag cctgggtgat cggcaacggc     28020
     cacttggttg cgatccagca cgccgatttc gctacccgat cagcgaccaa atcgcgcacg     28080
     tggtcgagat ggcgtggtag ccggtgcatg ccgaggctgc ccgccggctt aggcgcgttc     28140
     caccacacgc ttgacggtct tgtgcttggt tcggcacaac tctgcggtct cacgatcggt     28200
     tccggcttcc tgacaggtag aatgatgttc atttgctccc tcacagactc agacaaaact     28260
     gaagtgagcg aacaacgcga cctgccacga agctctcgat cgcagttgtc aggtggaggg     28320
     actggtctag atattttagc cgagttcttt gagctggcgc accaaccgag ccttctgatc     28380
     atcggtatca ttgtactgtg tagtagtcga tgcccaagtc ggtgtaggca acttgggcgt     28440
     ggatgatcgc cagaatggtg tgttcgatcg cggtagcagc ttttatttca gcttgccttg     28500
     ccgaattggc ggtgcagact ccggaatcgc gtgctcagac gcgtacgggt tatgagagac     28560
     cgcccacgtc cccgcaatgg caacgctgca gaactgcagc gttgccattg cggggacgtc     28620
     gtcttcctcc ttttgccgat ggactcgttg ttacccggac ataatccgat ccacgaagct     28680
     aaatgatcgg cggttgggaa ccacgacata tttacctcga tttcggcgat gaccgtctgg     28740
     gttgccagct taccaattcc aggagtcgtt atcagaggat cccgttgacg agcgaacggg     28800
     gggtgactgt cgaatctatg cgcactttca accggttgat catcaagttg aaaccatcaa     28860
     tgtgggccag ttgcagtctg gccagcggag tattctgatc cgccatcaga aaatccaaag     28920
     tctttgttag ataagggatt ttctttagta tcagccagca gaacaaatcg gccagcaccg     28980
     cgggatcgcg ctcccctcga tatcaacgta gtgatccttg tcctgcccga catgctgagg     29040
     taataggagg ctacagaatc cggttcaagg ccgtcttctt agaatacttt gtgcagcctc     29100
     agggtttcct gagtatgctc ctcggttaac ttccggtggt atcgggtaaa ttcccggtac     29160
     cgccgcgatc tccgccgacg tgatgaaact cccgcgcagc agacccacct cgtgcaactg     29220
     tgccagccag accgcatcag tggcgtcggt cttgcgaaat ggaacattct tgacgtggtt     29280
     agctttgcac agcaggattt caaatccatt gacttcagcc aaggcatgaa acacaggcct     29340
     tcagtacact tccgtttcct ccattctacg tgtgtaactt gtccggcgtg aagtcattcc     29400
     gttatctata taaactcccc gtagaacatc acgaccttac tcactttctg cgcacgtggt     29460
     tcgtcgcgcc gctacgatcg tccggtacgt ggactgctac cgccacttgt cgcgtattta     29520
     cattgattcc ggcaaccttc gagaacacga tctccatcat caacgcttcc ttcgctcacc     29580
     actaaggtgt gtcactcgcg gagcgtacga aacattcgaa acccaggcat gtgctcacag     29640
     cagcaatccg gagtacctcc cgtcgtgcac ttccagcgtc actctaaaat caatacaaac     29700
     ttttaaaatg ccaatatgag ccgacagcag cgggtgacgt accaccaagt ttcaaccacc     29760
     cgcgagtgct cagccagggg tataatcatt cctcacctgg tcggttcggg tgactgttgg     29820
     cgcaaatcac tgtcaccgtc ccggctgcga gcttcctgat cgacatgaca agcaaggaaa     29880
     cgagacttca ttacctagcc accagtggga acatccatct ggtcgttcat ggggactttc     29940
     acatggctac ggccacagtt catttgtgca acaagatacg ccttcacgaa gatccttgat     30000
     gactctatgc tgcaatgtat ttcgtaggca aattgatgta atttttccta tccttctgta     30060
     ggaaattcta gcacagcaga agcgacaaga atagcggcaa tcgttaccaa acgaaaggag     30120
     aaaataggtt gtttaaattt gaatttggcg gatttcagtg tgctaacatt ggaggtgaac     30180
     gccgcgctta tattgacttg ccggtaacgt agtgcaggtt cggggaaaat tattcattga     30240
     tagcggtcaa tgaggctgta tactgggagt actgtgcaaa tcatacctgg gtgatgaaac     30300
     aatctgtgcc aaagaggtgt cgttggtgac ttcgtttatg gagccgctgc aggtcgttaa     30360
     ccaggttaag tcggtgcaga aggcgtcgtg cttagtgcaa tagcagctag tcaagtggtg     30420
     gcgctcattc cttaagaagc gctcattcct taagaagcta gtcgaagact agcttcttaa     30480
     ggagcctgtg cagccaggtt tcagtgatca actctccgag atcggggatg tcgatctagg     30540
     agagtttgac caacatctct ggatagccgt cgaaatgagg gtggtgaaat atactcctgg     30600
     gtcgtcggcg atttaaagcg aacttgacac ccgtatcaga agacccggat atcgataatg     30660
     ttgccgctcg gtgggtcggt tcagtgtgct gccagagcgt cacggtcaga ttgcgcaggg     30720
     gtcgttccca cgcatcggtt tcttactgac tcgccaaatg tgcggtggac tgcttggtgg     30780
     tgcgtggcaa ccgccccacg atgctttgcg acgtcgttcc acgtggccac gtgtcgacta     30840
     tggtgaagct tggtgtcggt tgttggctga gcccacgcga gggacaagcg tgatgtaatc     30900
     ggccttgttg gaccaccggg cttgtctcgt ggagtaggtc ggtatcgaag attcgggagg     30960
     ttgtttttgt caggaagtag cgcgttgccc tctgacgact tgtgtgattc gccgccagcc     31020
     gcgcgtctgg tcggtggcct cgcgatcctg accagttgtt ggccgattat cgcgccatgt     31080
     gggcgcagca gttgttgttt gacgtgcgtg atggccggtc tggttgcacc gtcctggtgc     31140
     cagtgtgccc acactctggc accaggaggc actgccgtta atgcttactc tggaagactg     31200
     ggccacattg gaatccagtg tcgtgcaacc tagccggttg ctcgatgcgg tgctcactga     31260
     cctgtatggg ccgcgtcgct gcgtcaccag cggagtgttt ccggctgtgc tgctgttcgg     31320
     ccaccctggc tacgtccggg cggtcaatgc gatcgaagta ccgggccgta atcagttttt     31380
     ttatacatgg ctgtgccatc agccggaacc ggtccgggag ctttactgtc aatctggatt     31440
     ggccgcaggt actggcggga gccgggtatg cgctggccga ccgtcgggtc gtcgcgcacg     31500
     ctgttcctga cctgtacgaa cgggtcgggt tgcccccggc atcaccgttc gcgcagacgt     31560
     tgctgccggc gctgatcgat gccacacccg aggccttcga agatccggtg gttgtggtgc     31620
     ccacccccgg catccgcttc gaaatagaat tctaccaggt ctatctagta tttgtgttgg     31680
     gtttcccgct ggtgggaagt gctgacttag tggtccgcga tggcaagctg tggatgcggt     31740
     cgttgagcac cctgaaaccg ggtcgacatg gtgttgcacc gggtcaatgc cgactacgcc     31800
     gatcagctgg atttgctgtc cgatttcagg ccgagcgtgg tgggtttggt cgaagtgttg     31860
     taacgcgggg cgcgtgactg tggtcaacgc tctgggcagc ggtatcctgg aaagcgcagg     31920
     gatcatgcgg ttattgtccg agttgtcgct gtagctgctt ggcggagccc cgctgctgct     31980
     ggtggccgtc cgtgtcgagg acgcgccctg gcagtgggtt ggtcaggagc tgtcacattt     32040
     ttcctctgcg tccactgacc acatacctag gagggttgaa tgtcgccggt gttggggtgc     32100
     ggttgttcat cgtctcacaa tgcggtggtt acgcaccgat gatcggtggc ctggggtaca     32160
     cccttgcccc gggtaacgtc tcatgcaatc ttaataccgt tgcggctaag gatatccggt     32220
     tcaggacgcc gacccgggac cgctccgggg tcaccattcc gtcggttgac ttggcggcgg     32280
     taaaggctgg cggcactcgc ggcatcagct cgccaaggtt gctgttcgac atgttttggg     32340
     ttgggcattg cgccgagctc gctgaggtca tggctcgatt actggttttc acccgcgagc     32400
     ggtaccatga attccatcac cgcgaggaca ctgacggtag cgaatccgtg ctcgctgcac     32460
     tcgggcaggt catcggcatc gatattgctg acgcgcaagc gacactttgg tgactgacct     32520
     atgtctcgga gcgttcaaga tcgctgacgc agtcggtcgc atggcttgga ctggttgagt     32580
     gggtggtgcg ggatcaaatg tcgaaggaca tatggatggt gctcggcagt gtcgagtggt     32640
     cactgacgca gctgtctgca tcggtcccgg tgacgtctgg gcagtccctc gaaccgggca     32700
     aactggccaa tccagcgagt catccgagct cgctgacgac atcaaattcg ccccggtgca     32760
     cgccacgacg ttggcgttgt cccaggtggc ggccgaatcg gtggtgcgtg atgtcgactt     32820
     gaccatgacc aatatcggca aacggatcga acgcagggag tggctgacct cgctgttgga     32880
     ggccatctca tcgaaggacc gcagccgtgc tgccgagcaa acgatcattg agtccacgca     32940
     gatggcctgc gaatcgtcgg tgatctacct gcggcacaac cttcgtgctg tgaatgttgc     33000
     tacggttgcc gagctggtac ttttcgaggt cgagaacccg aggttgctgg tctacccgct     33060
     ggagcggctg cggaccgact tgtggcagtt acctggagct tcgggctcgt cgcgggctga     33120
     acggttggcc gacgacataa gtatccggtt gcgccggctc gatccggcag atttcgatgt     33180
     ggtcactgcc aacggggagc gcgccaagtt ggcggggttg ttgaccggga tacacaatgg     33240
     gctgcttgac ccgaccgacg ttaccaccgc cacccagctc tcgctgcccg gcgaaatgca     33300
     gccaatgtgg gtaccagacc agcgttgggt gatgctatca tgtcacatga agtggacgca     33360
     gctgacgtcg cggcggtacc gagttagtca ccgtactgaa taccgctatt ccgacgttgt     33420
     caccagttcc tatggccgtg ggttcctcac gccatgcgat tccttgcgcc agcgctgtgt     33480
     cgaccatcgg ttgcatatcg tgcctgttcc cgctgacagc tcgataagcc gcgacagcta     33540
     cggcaacatc agctcctact tccacgtcac cgagccgcac tgcaccctga ctgtcaccag     33600
     tgaatccatc gtcgacgtgt acccgactcc acccgagctg ttcaccagtg ggccggcgtc     33660
     ggcaccgtgg gaggcggccc ggccgaccgg gaggcgggga gtgctggcca ctgaattcac     33720
     cctggatctg aatccgccgg agatcactga cgaagtgcgg cagtacgctg cgccaagttt     33780
     cgagccgcag cgtccactga tcgaggttct gcgcgacctc accacacgga tctacgccga     33840
     tttcacttat cggtcgggct ctacgacgat ttccaccgga gttaacgagg ttctgttggc     33900
     ccgagaaggg gtatgtcaag atttcgcccg gttggcgatt gcctgcttgc gtgccaacgg     33960
     tctggcggct agctatgtat ccgggtactt ggccaccgat cctccaccgg ggaaggatcg     34020
     tatggttggt atcgatgtga cccatgcctg ggcctcggtc tggacgccgc aacagtctgg     34080
     ccaatgcgag tggttgggac tggatcccac caatgaccag ctggtcgacg agcgatacat     34140
     tgtcgtcggc cagggccgcg actacgtgaa cgtgccaccg ctgcgcggca tcatctacac     34200
     taactctgag aacagtgtga tcgacgttgc cgttgacgta gcgccctgcg aaggcgacgc     34260
     actgtatgct tgacttccga tgttctaact gcggtcagcg cctgacgttc gagaacttcg     34320
     tgtgtttgtc ctacggcagc gcgctggggt tttcgctgaa ggatatggcg ctgctggtga     34380
     ttggtgacgc cgagcacgtc ggtgccattg ttgccggaga ttatcaaccg tgtgccaaat     34440
     cttcatctgg accaatgcaa ttggttggtc cccgttgatc aacctggcgg gctgtgcacg     34500
     tcatgcgtgt tggactcaac aacggcagca cgatgcgtac acacaccatt gacctggctg     34560
     agttcgtccg agtctaggag gctaagcggc ggctgatcgc ggaattcaac gaactaaagc     34620
     tgccgattgt cgagcgtgac cagaatcccg actttggact ggcgttcatc tgttgtccag     34680
     cgagcactag aaggtagtca ccgagcatga cggcggcata atcgccctag agttaaccga     34740
     gggtgatgat gttcaccgca agcagttgcg ggttgaaatg aacgagtcat acccgcaccc     34800
     tgctcgggca cttccgccac gggatcggga gtgactacat ttattaatta aaccagttga     34860
     tcaccaattc gggtgcatac ttggactatt gccgcggatt gttcggtgat ctcgacgcca     34920
     actaccccga gttgttagct tgtggcgccc tgcccgctga ctggtaggaa tgctttgtgt     34980
     catcgtatga tgccatgcac gctgctcagg attatgctga gatgtttgtt cacaatactg     35040
     tacatacgcg atgtcctgga catctttagt gtggtgcggt ttgacgtcgg cgtcagtaac     35100
     ctttgagcga agtgtgttcg gcttcagtgc ttttcccacc atcatcgaca tgtggctgcc     35160
     gttgtcctgg ttgctgaaca tggtcaaccg ttcgatgggc catgacgacc tatactcgtt     35220
     cgtgttgatg tccgccgttt tggacaagat gcagttcact cacgccgtcg tcgacgatgt     35280
     gactgccaac ctaaacagca gcacatgagg tacgtggccg tggttaggcg aattgggacc     35340
     cggcggcagt ggaccgtcac tgggggtgag ggagaagctc cgtaaccaga cggtggtgga     35400
     tagtcgtaaa ggttctggtt gccgctctgc tagttggccg ggttagctag atagttcggg     35460
     gttggcttat tactttgatt cgtttgctag tttgttgtgg ggacccgttg ggtacccgaa     35520
     tcatcggggt ttaccgtgac tgacttgtct gtccttcgtg gtatttctaa tgttgtgtcc     35580
     gacagtctgt ttgatttgcc tggcgcgccg cagccgaccg actacggcct gggtggctcg     35640
     accggggtcc cgctggcggt gcggatgcgt ccggcatcgc tggacgagct ggttggacag     35700
     ggtcacttgt tggcgccggg atcgccgctg cgccgccttg tcgagggctc gggtgtggtg     35760
     tcggctattc tccatggccc gccgggatgc ggtaagacga ccctggcagc gctgatctcg     35820
     caggcgaccg ggcaccggtt cgaggcactg tcggcgttgt cggcgggtgt caaagacgtt     35880
     cgagctgttt tgaagattgc acgtagtgcg ttgctctcgg ggaagcggac tgtgctgttt     35940
     atcgacgaag tgcaccgatt ctccaagact cagcaggacg ccctgctttc cgcggtggag     36000
     aaccgggtgg tgttgctggt cgcggcgacc accgagaacc cgtcgttttc agtggtggcg     36060
     ccgctactgt ctcgatcgct gatccttcag ttgcggccgc tgaacgctga cgacatccgt     36120
     gccgtggtgc agcgggccgt cgatgatccc cgcggcctgg gaggacagat cgctgtggca     36180
     cccgaggccg tcgacttgtt agttcggttg gccgccggcg acgcccgacg ggttttgacc     36240
     gcattggagg tggccgccga agccgtccaa accggtgacg agctgacggt cgcgaccatt     36300
     gaacaatcct tggacaacgc tgcagtgcgc tacgaccggg acggtgatca gcattatgat     36360
     atcgtcagcg ccttcatcaa atcggtgcgt ggctctgacg tggatgctgc gctgcactat     36420
     ctggcgcgca tgttgattgc cggggaggat ccacgattca tcgcgcgccg gctgctgatc     36480
     ctggctagcg aagatatcgg cctggccgac tcgaccgcgc ttccgcttgc ggtcgctgcc     36540
     gcgcagactg tgcagctaat aggcatgccc gaagcccagc tggcgctggc acatgccacc     36600
     attcatttgg ctactgcacc gaaatcgaac gccgtcatga ccgcgctggg ttccgcaata     36660
     gatgatatca aagctggtaa ggccggtttg gtaccggctc acctgcgcga cggacattac     36720
     tccggtgcgg cggcgctggg caacgccaaa ggctacaagt attcccatga tgaccccgac     36780
     ggtgttgttg cccaacagta tccgccgtat gagctggtgg aagtggacta ctatcggcct     36840
     accggtcgtg gcggtgaacg tgagctcgtc ggtcgactag accggctgcg agcgataatc     36900
     cgcggccggc gaggctagcc gttcgagtag tgtgcggctg gctgcacgct tggcatcaga     36960
     ccagcttgag caccctcaag tgcgcgatcg ccggatcgaa ttcggccacg ttgagtacct     37020
     cggcttccac aaatccagac ctgtttgctg cgcaacttta acttggttga ccggtcgcgg     37080
     ttgctgatcg ccattgcgtt gatgctgtcg aacgtcgagc aggacaccgt acgccggaat     37140
     acgggatagt cgaccatcag gctggtgctg cagaacccgt tgagtttttc cagttctgga     37200
     agcactcatg tccggtacga tccatcgatc ggctgcgctg gtcggatacc gttttgagcc     37260
     agatagcccg tgtgcatgcg cccttgcacg agcggtggtt acgctgccag cagagcgatt     37320
     cccattcttc gacctgtgtg ctgccgttga acatctgcac agcctgatcg cgaatgcgcg     37380
     ccagccgccc atcgcctgca cgttctcccg agtgagctgg tggtgatgca tctgccggac     37440
     tgttcggtcg acaaaaagcg acactctgat acacccgtcg atctcctgca gggcaggtca     37500
     tgactacatc gcgaatggaa tgtgtgcaat tcctatgttg accgacaggg gttgcgcctg     37560
     gatggtggta gagcgtgcgt acacgatcga ctccaatcct atctctgagg cagagtcccg     37620
     gtaacgctac cggttcatca agctgctttc ttccgaccac ttaggcgtgg caatgctgct     37680
     tgcggggctt tctcccgggt tgtgtatcgg attggcaggt cgacaagcca cgcccgtagg     37740
     ctgggctgcg tgcataccga tgtgctggat gtgaacactg cgtgtcgtcg catcgtggat     37800
     cttaccgacg cggtacgcga attcggcccg actcacagcg atgaccggta gtctttgcag     37860
     tcgaaagtgt cgttagacgg ccttctaatt gtctggcgaa taggttttgg aatcgacccc     37920
     aagcacgttg cgatgttgtc ccggcagagc cgccggaatt aagggaacta gggaagaaga     37980
     atacttagag tgcaaacaca cgagatcagg aagcggttcc ttgatcattt tgtgaaggcg     38040
     ggccacaccg aggtgcctag cgcgtcagta atcctcgatg accccaacct gttgttcgtc     38100
     aacgctggca tggtccagtt cgtgccgttc tttctggggc agtgtacgcc gccgtacgcg     38160
     acggccacca gcatccagaa atgcatccgc actcctgaca tcgacgatgt gggtatcacc     38220
     acccggcaca acaccttttt ccagatggcg ggcaatttct cgttcgggga ctacttcaag     38280
     cgcggggcta tcgaactggc ctgggcgttg ctgactaaca gctttgccga cgggggctac     38340
     gggctggacc cagagagact ctgggccacg gtgtatctcg atgacgacga ggctgcaggc     38400
     ctatggcagg agatcgccgg actgccacct gagcgaatcc agcgtcgtgg tatggccgac     38460
     aactactggt cgatgggcat ccctgggcca tgcgggccgt cgtcggagat ttactacgac     38520
     cgcgggcccg agttcggccc cgaaggcggt cccatcgtca atgaggaccg ctacctcgag     38580
     gtctggaacc tcgtgttcat gcaaaacgaa cgcggtgagg ggactaccaa ggaggactac     38640
     gagatccgcg gaccgctgcc acgcaagaac atcgacactg gcatgggtgt tgagcggatt     38700
     gcgttggttc tgcagggcgt gcacaacgtc tacgagatcg atctgctgcg gccggtgatt     38760
     gacctagtgg cgacccgcgc accgcgcccg tatgaccccg aaaatga                   38807
//