EBI Dbfetch

ID   AL008609; SV 1; linear; genomic DNA; STD; PRO; 39228 BP.
XX
AC   AL008609;
XX
DT   29-OCT-1997 (Rel. 53, Created)
DT   16-APR-2005 (Rel. 83, Last updated, Version 6)
XX
DE   Mycobacterium leprae cosmid B1788.
XX
KW   43L; 6-phosphogluconate dehydrogenase; ABC-transporter; antigen 43L;
KW   cytochrome p450; dehydrogenase; gcvH; gcvP; glcB;
KW   glycine cleavage system h protein; glycine dehydrogenase (decarboxylating);
KW   gnd; guaB; inosine-5'-monophosphate dehydrogenase; LEPREP;
KW   malate synthase G; oxidoreductase; pgsA; phosphatidyltransferase;
KW   preprotein translocase seca subunit; pseudogene; secA;
KW   TPP-requiring enzyme.
XX
OS   Mycobacterium leprae
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium.
XX
RN   [1]
RP   1-39228
RA   Skelton J., Churcher C.M.;
RT   ;
RL   Unpublished.
XX
RN   [2]
RP   1-39228
RA   Parkhill J., Barrell B.G., Rajandream M.A.;
RT   ;
RL   Submitted (21-OCT-1997) to the EMBL/GenBank/DDBJ databases.
RL   Mycobacterium leprae sequencing project, Sanger Centre, Wellcome Trust
RL   Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: barrell@sanger.ac.uk
RL   Cosmids supplied by Dr. Stewart T. Cole, [3] Unite de Genetique Moleculaire
RL   Bacterienne, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex
RL   15, France Requests for cosmids should be sent to Karin Eiglmeier
RL   (kei@pasteur.fr).
XX
RN   [3]
RP   1-39228
RX   DOI; 10.1111/j.1365-2958.1993.tb01111.x
RX   PUBMED; 8446027.
RA   Eiglmeier K., Honore N., Woods S.A., Caudron B., Cole S.T.;
RT   "Use of an ordered cosmid library to deduce the genomic organization of
RT   Mycobacterium leprae";
RL   Mol. Microbiol. 7(2):197-206(1993).
XX
CC   Notes:
CC   
CC   The Sanger Centre is funded to complete the sequence of M. leprae
CC   by the Heiser Program for Research in Leprosy and Tuberculosis of
CC   The New York Community Trust.
CC   
CC   Work in Paris is supported by the Heiser Trust, the Association
CC   Francaise Raoul Follereau and the Groupement de Recherches et des
CC   Etudes des Genomes (GIP-GREG).
CC   
CC   Details of M. leprae sequencing at the Sanger Centre
CC   are available on the World Wide Web.
CC   (URL, http://www.sanger.ac.uk/Projects/)
CC   
CC   CDS are numbered using the following system eg MLCB33.01c.
CC   ML (M. leprae), cB33 (cosmid name), .01 (first CDS),
CC   c (complementary strand).
CC   
CC   The more significant matches with motifs in the PROSITE
CC   database are also included but some of these may be fortuitous.
CC   
CC   The length in codons is given for each CDS.
CC   
CC   Usually the highest scoring match found by fasta -o is given for
CC   CDS which show significant similarity to other CDS in the database.
CC   The position of possible ribosome binding site sequences are
CC   given where these have been used to deduce the initiation codon.
CC   
CC   All CDS over 100 codons have been analysed.  Gene prediction
CC   is based on positional base preference in codons especially
CC   where there is an increase in the observed/expected third
CC   position G + C.  CAUTION:  We may not have predicted the
CC   correct initiation codon.  Where possible we choose an
CC   initiation codon (atg, gtg, or ttg) which is preceded by an
CC   upstream ribosome binding site sequence (optimally 5-13bp
CC   before the initiation codon).  If this cannot be identified
CC   we choose the most upstream initiation codon.
CC   
CC   IMPORTANT: This sequence MAY NOT be the entire insert of
CC   the sequenced clone.  It may be shorter because we only
CC   sequence overlapping sections once, or longer, because we
CC   arrange for a small overlap between neighbouring submissions.
CC   
CC   Cosmid B1788 is overlapped at the 5' end by EM_BA:MLB38COS.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..39228
FT                   /organism="Mycobacterium leprae"
FT                   /mol_type="genomic DNA"
FT                   /clone="cosmid B1788"
FT                   /db_xref="taxon:1769"
FT   misc_feature    1..2183
FT                   /note="overlap with EM_BA:MLB38COS L01095 M. leprae cosmid
FT                   B38 from: 34883 to: 37065"
FT   CDS             complement(<1..256)
FT                   /transl_table=11
FT                   /gene="43L"
FT                   /product="antigen 43L"
FT                   /note="MLCB1788.01c, 43L, antigen 43L, partial CDS, len:
FT                   >85 aa; almost identical to N43L_MYCLE P46842 antigen 43l
FT                   precursor (97.6% identity in 85 aa overlap), also highly
FT                   similar to M. tuberculosis TR:Q50906 (EMBL:X80268), apa,
FT                   45/47 gene precursor (325 aa), fasta scores; opt: 246
FT                   z-score: 289.6 E(): 5.6e-09, 52.1% identity in 96 aa
FT                   overlap. Contains N-terminal signal sequence"
FT                   /db_xref="GOA:P46842"
FT                   /db_xref="InterPro:IPR010801"
FT                   /db_xref="UniProtKB/Swiss-Prot:P46842"
FT                   /protein_id="CAA15433.1"
FT                   /translation="MNQVDLDSTHRKGLWAILAIAVVASASAFTMPLPAAANADPAPLP
FT                   PSTATAAPSPAQEIITPLPGAPVSSEAQPGDPNAPSLDPN"
FT   misc_feature    35..35
FT                   /note="conflict: T is C in EMBL:MLB38COS"
FT   RBS             complement(265..270)
FT                   /note="possible RBS upstream of 43L"
FT   CDS             complement(482..787)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.02c, ABC-transporter pseudogene fragment,
FT                   len: 101 aa; highly similar to part of TR:P95155 O05126,
FT                   MTCY359.14c, modC, ATP-binding subunit of ABC-transport
FT                   system (369 aa), (42.7% identity in 103 aa overlap)"
FT                   /db_xref="PSEUDO:CAA15434.1"
FT   CDS             complement(863..1033)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.03c, ABC-transporter pseudogene fragment,
FT                   len: 56 aa; highly similar to part of TR:P95155 O05126,
FT                   MTCY359.14c, modC, ATP-binding subunit of ABC-transport
FT                   system (369 aa), (75.0% identity in 56 aa overlap)"
FT                   /db_xref="PSEUDO:CAA15435.1"
FT   CDS             complement(1193..1321)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.04c, ABC-transporter pseudogene fragment,
FT                   len: 42 aa; highly similar to part of TR:P95155 O05126,
FT                   MTCY359.14c, modC, ATP-binding subunit of ABC-transport
FT                   system (369 aa), (81.0% identity in 42 aa overlap)"
FT                   /db_xref="PSEUDO:CAA15436.1"
FT   CDS             complement(1315..1467)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.05c, ABC-transporter pseudogene fragment,
FT                   len: 50 aa; highly similar to part of TR:P95155 O05126,
FT                   MTCY359.14c, modC, ATP-binding subunit of ABC-transport
FT                   system (369 aa), (70.0% identity in 50 aa overlap).
FT                   Contains PS00017 ATP/GTP-binding site motif A (P-loop)"
FT                   /db_xref="PSEUDO:CAA15437.1"
FT   misc_feature    complement(1354..1377)
FT                   /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
FT   CDS             complement(1473..1667)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.06c, ABC-transporter pseudogene fragment,
FT                   len: 64 aa; highly similar to part of TR:P95156 O08061,
FT                   MTCY359.15c, modB, membrane spanning subunit of
FT                   ABC-transport system (264 aa), (67.2% identity in 64 aa
FT                   overlap)"
FT   CDS             complement(1806..2075)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.07c, ABC-transporter pseudogene fragment,
FT                   len: 89 aa; highly similar to part of TR:P95156 O08061,
FT                   MTCY359.15c, modB, membrane spanning subunit of
FT                   ABC-transport system (264 aa), (60.7% identity in 89 aa
FT                   overlap)"
FT                   /db_xref="PSEUDO:CAA15439.1"
FT   CDS             complement(2076..2180)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.08c, ABC-transporter pseudogene fragment,
FT                   len: 34 aa; highly similar to part of TR:P95156 O08061,
FT                   MTCY359.15c, modB, membrane spanning subunit of
FT                   ABC-transport system (264 aa), (68.8% identity in 32 aa
FT                   overlap)"
FT   CDS             complement(2418..2804)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.09c, ABC-transporter pseudogene fragment,
FT                   len:128 aa; highly similar to part of TR:P95157 O05125,
FT                   MTCY359.16c, modA, molybdenum-binding subunit of
FT                   ABC-transport system (261 aa), (42.3% identity in 97 aa
FT                   overlap)"
FT                   /db_xref="PSEUDO:CAA15441.1"
FT   CDS             complement(2801..3058)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.10c, ABC-transport system pseudogene
FT                   fragment, len: 85 aa; highly similar to part of TR:P95157
FT                   O05125, MTCY359.16c, modA, molybdenum-binding subunit of
FT                   ABC-transport system (261 aa), (61.2% identity in 85 aa
FT                   overlap)"
FT   RBS             3300..3306
FT                   /note="possible RBS upstream of MLCB1788.11c"
FT   CDS             3308..3982
FT                   /transl_table=11
FT                   /gene="MLCB1788.11c"
FT                   /product="oxidoreductase"
FT                   /note="MLCB1788.11, probable oxidoreductase, len: 224 aa;
FT                   similar to eg. FABG_ECOLI P25716 3-oxoacyl-[acyl-carrier
FT                   protein] reductase (244 aa), fasta scores; opt: 157
FT                   z-score: 273.8 E(): 4.2e-08, 27.9% identity in 240 aa
FT                   overlap. Also highly similar to M. tuberculosis
FT                   oxidoreductase MTCY359.17 (80.4% identity in 224 aa
FT                   overlap)"
FT                   /db_xref="GOA:O32906"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/TrEMBL:O32906"
FT                   /protein_id="CAA15443.1"
FT                   /translation="MAVDVLVTGGNTDLGRTIAEGFRNDGHKVTLVGPRRADLEVVAKE
FT                   LDVDTIVCNTTDPASLDEARGLFPRHLNTIVNVPTLGFDTGDPRTFSLSDTANAWHNEL
FT                   DATVLSAVLTVQSVGDHLRSGGSIIGVLAENPPAGSVDAAIKAALSSWVAGQAGVFGTR
FT                   GITVNAIACGRSVQAGYEGLSRMPPHVATEITRLALFLTTPASRHITGQTLHVSHGALT
FT                   HF"
FT   CDS             4050..4391
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.12, probable pseudogene fragment, len: 113
FT                   aa; similar to part of M. tuberculosis hypothetical protein
FT                   TR:P95159 (EMBL:Z83859) MTCY359.18 (307 aa)(40.4% identity
FT                   in 114 aa overlap)"
FT                   /db_xref="PSEUDO:CAA15444.1"
FT   CDS             4392..4712
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.13, probable pseudogene fragment, len:106
FT                   aa; similar to part of M. tuberculosis hypothetical protein
FT                   TR:P95159 (EMBL:Z83859) MTCY359.18 (307 aa)(42.6% identity
FT                   in 94 aa overlap)"
FT                   /db_xref="PSEUDO:CAA15445.1"
FT   CDS             4737..4913
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.14, probable pseudogene fragment, len: 58
FT                   aa; similar to part of M. tuberculosis hypothetical protein
FT                   TR:P95159 (EMBL:Z83859) MTCY359.18 (307 aa)(43.1% identity
FT                   in 58 aa overlap)"
FT                   /db_xref="PSEUDO:CAA15446.1"
FT   RBS             5160..5164
FT                   /note="possible RBS upstream of MLCB1788.15"
FT   CDS             5174..6574
FT                   /transl_table=11
FT                   /gene="MLCB1788.15"
FT                   /product="dehydrogenase"
FT                   /note="MLCB1788.15, probable dehydrogenase, len: 466 aa;
FT                   similar to eg. DHNA_ECOLI P00393 nadh dehydrogenase (ec
FT                   1.6.99.3) (433 aa), fasta scores; opt: 438 z-score: 436.1
FT                   E(): 3.8e-17 26.6% identity in 428 aa overlap. Also higly
FT                   similar to two M. tuberculosis dehydrogenases, MTCY359.19
FT                   (TR:P95160, EMBL:Z83859) (463 aa) (90.2% identity in 460 aa
FT                   overlap), and MTCY04D9.04c (TR:P95200 EMBL:Z84725) (470aa)
FT                   (62.5% identity in 467 aa overlap)"
FT                   /db_xref="GOA:O32907"
FT                   /db_xref="InterPro:IPR013027"
FT                   /db_xref="UniProtKB/TrEMBL:O32907"
FT                   /protein_id="CAA15447.1"
FT                   /translation="MNAQPAATAAQDRRHQVVIIGSGFGGLNAAKKLKRANVDIKLIAR
FT                   TTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQRNIQVLLGNVTHIDLANQCVVSELL
FT                   GHTYETLYDSLIVAAGAGQSYFGNDQFAEFAPGMKSIDDALELRGRILSAFEQAERSND
FT                   PERREKLLTFTVVGAGPTGVEMAGQIAELADHTLKGAFRRIDSTKARVVLLDAAPAVLP
FT                   PMGEKLGQRAAARLQKMGVEIQLSAMVTDVDRNGITVQDSDGTVRRIESACKVWSAGVS
FT                   ASRLGRDLAEQSLVELDWAGRVKVLPDLSIPGYRNVFVVGDMAAIDGVPGVAQGAIQGA
FT                   KYVANNIKAELGEANPAEREPFQYFDKGSMATVSRFSAVAKIGPLEFSGFIAWLMWLVL
FT                   HLMYLIGFKTKITTLLSWTVTFLSTRRGQLTITEQQAFARTRLEQLAELTAESQSTAAA
FT                   NRATMRAS"
FT   RBS             6948..6951
FT                   /note="possible RBS upstream of MLCB1788.16"
FT   CDS             6960..7229
FT                   /transl_table=11
FT                   /gene="MLCB1788.16"
FT                   /product="hypothetical protein MLCB1788.16"
FT                   /note="MLCB1788.16, questionbable ORF, len: 89 aa"
FT                   /db_xref="UniProtKB/TrEMBL:O32908"
FT                   /protein_id="CAA15448.1"
FT                   /translation="MNCSPNALSNGALVLKLFGTSTRVYIITGSTYAHQSTTNRYWSCP
FT                   GRQCSESTEGHGRPQDTSTVIAARPAKNRQGCPNLAKVGCESRR"
FT   RBS             7392..7396
FT                   /note="possible RBS upstream of MLCB1788.17"
FT   CDS             7408..7836
FT                   /transl_table=11
FT                   /gene="MLCB1788.17"
FT                   /product="hypothetical protein MLCB1788.17"
FT                   /note="MLCB1788.17, unknown, len: 142 aa; highly similar to
FT                   M. tuberculosis putative repressor TR:P95163 (EMBL:Z83859)
FT                   MTCY359.27 (138 aa); fasta sxcores; opt: 736 z-score:
FT                   1419.4 E(): 0, 95.1% identity in 123 aa overlap"
FT                   /db_xref="GOA:O32909"
FT                   /db_xref="InterPro:IPR011991"
FT                   /db_xref="UniProtKB/TrEMBL:O32909"
FT                   /protein_id="CAA15449.1"
FT                   /translation="MAKLTRLGDLERAVMDHLWSRQEPQTVRQVHEALSARRDLAYTTV
FT                   MTVLQRLAKKNLVSQIRNNRAHRYAPVHGRDELVAGLMVDALDQAEDSDSRQAALVHFV
FT                   ERVGADEADALRRALAELETHQRHVRHLVALQRTTEGD"
FT   RBS             7828..7831
FT                   /note="possible RBS upstream of MLCB1788.18"
FT   CDS             7841..8791
FT                   /transl_table=11
FT                   /gene="MLCB1788.18"
FT                   /product="hypothetical protein MLCB1788.18"
FT                   /note="MLCB1788.18, unknown, possible membrane protein,
FT                   len: 316 aa; highly similar to M. tuberculosis hypothetical
FT                   protein TR:P95164 (EMBL:Z83859) MTCY359.28 (322 aa), fasta
FT                   scores; opt: 1788 z-score: 2478.8 E(): 0, 87.2% identity in
FT                   320 aa overlap"
FT                   /db_xref="GOA:O32910"
FT                   /db_xref="InterPro:IPR001915"
FT                   /db_xref="UniProtKB/TrEMBL:O32910"
FT                   /protein_id="CAA15450.1"
FT                   /translation="MSALAFTILAVLLVGPTPTLVARSTWPLRAPRAAMVLWQTIALAA
FT                   ALSTFSAGIAIASRVLMPGPDGRLTASVIGAAGRLGWPLWAAYVAAFALTVLVGARLIV
FT                   AIVRVAIATRRRRAHHRMVVDLVGVGHNAALAQPCARARDLRVLEVAQPLAYCLPGVRS
FT                   RVVVSEGALTKLNDTEVTAILTHERAHLRARHDLVLEAFTAVHAAFPRLVRSSAALSAV
FT                   RLLVELLADDAAVRAAGRTPLARALVACASGQAPSGALAAGGNTTVLRVRRLSGRSNSA
FT                   VVSAAAYLAAAIVLLVPTVALAVPWLTELQRLFNI"
FT   RBS             8908..8911
FT                   /note="possible RBS upstream of gnd"
FT   CDS             8922..10382
FT                   /transl_table=11
FT                   /gene="gnd"
FT                   /product="6-phosphogluconate dehydrogenase"
FT                   /note="MLCB1788.19, gnd, 6-phosphogluconate dehydrogenase,
FT                   decarboxylating, len: 486 aa; highly similar to many eg.
FT                   6PGD_ECOLI P00350 6-phosphogluconate dehydrogenase,
FT                   decarboxylating (468 aa), fasta scores; opt: 1610 z-score:
FT                   1320.6 E(): 0, 51.9% identity in 464 aa overlap. Also
FT                   highly similar to M. tuberculosis gnd MTCY359.29 (86.8%
FT                   identity in 485 aa overlap)"
FT                   /db_xref="GOA:O32911"
FT                   /db_xref="HSSP:2PGD"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/TrEMBL:O32911"
FT                   /protein_id="CAA15451.1"
FT                   /translation="MQDMSAPESKTAIAQIGVTGLAVMGSNIARNFARHGYTVALHNRS
FT                   IAKTDTLLKEHGSEGNFVRTETIPEFLAALQTPRRVLIMVKAGDATDAVINELADVMEP
FT                   SDIIIDGGNSLFTDTIRREKAMRERGLHFVGAGISGGEEGALNGPSIMPGGPAESYTSL
FT                   GPLLEEISAHVDGVSCCTHIGPGGSGHFVKMVHNGIEYSDMQLIGEAYQLLRDGLGMSA
FT                   PQIADVFTEWNRGDLNSYLVEITAEVLRQTDIKTGRPLVDVILDKAEQKGTGRWTVQSA
FT                   LDLGVPITGIAEAVFARALSGSVLQRKAAIGLASGKLGNKPTDRETFIEDVRQALYASK
FT                   IVAYAQGFNHIQTGSTEFGWNITPGDLATIWRGGCIIRAKFLNRIKEAFDAAPDLASLI
FT                   VAPYFRSAVESAIDSWRRVVSTATQLGIPNPGFSSALSYYDALRTERLPAALTQAQRDF
FT                   FGAHSYGRVDARGKFHTLWSEDRSEVTV"
FT   CDS             10452..11888
FT                   /transl_table=11
FT                   /gene="guaB"
FT                   /product="inosine-5'-monophosphate dehydrogenase"
FT                   /note="MLCB1788.20, guaB, inosine-5'-monophosphate
FT                   dehydrogenase, len: 478 aa; similar to many eg; IMDH_BACSU
FT                   P21879 inosine-5'-monophosphate dehydrogenase (513 aa),
FT                   fasta scores; opt: 900 z-score: 1101.1 E(): 0, 37.7%
FT                   identity in 472 aa overlap. Also highly similar to M.
FT                   tuberculosis guaB MTCY359.30 (86.4% identity in 478 aa
FT                   overlap)"
FT                   /db_xref="GOA:O32912"
FT                   /db_xref="HSSP:1B3O"
FT                   /db_xref="InterPro:IPR005991"
FT                   /db_xref="UniProtKB/Swiss-Prot:O32912"
FT                   /protein_id="CAA15452.1"
FT                   /translation="MRFLDGHQPRFDLTYKDVFIVPHRSDVASRFDVDLSTYDGSGTTI
FT                   PVVVANMTTVAGQRMAETVARRGGLVILPQDLPIATVQQAVEFVKSRDLVIDTPVLLTP
FT                   NDSVSDATTLIHKRAHGVAVVAFEGRPIGLVRESSCLGVDRFTRVRDVATTDFVTAPVG
FT                   TDPRKIFDLLEHAPIDVAVLTNADGTLAGVLTRTGAIRAGIYTPATDARGRLRIGAAVG
FT                   INGDVAGKAQSLAEAGVDVLVVDTAHGYQVKTLEAIKCVASLNLGVPLVAGNVVSAEGT
FT                   RELLNAGATIVKVGVGPGAMCTTRMMTGVGRPQFSAVLECASAARKLNRHVWADGGVRH
FT                   PRDVALALAAGASNVMIGSWFAGTYESPGDLMRDRHDQPYKESYGMASKRAVVARTVAD
FT                   SSFDRARKALFDEGISTSRMGLDPDHGGVEDLIDHITSGVRSTCTYVGASTLAELHEKA
FT                   VVGVQSAAGFAEGHPLPSGW"
FT   CDS             12155..12655
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.21, probable pseudogene fragment, len: 166
FT                   aa; similar to part of hypothetical membrane proteins from
FT                   several organisms eg. M. tuberculosis MTCY359.31 TR:P95166
FT                   (EMBL:Z83859) (72.9% identity in 170 aa overlap)"
FT                   /db_xref="PSEUDO:CAA15453.1"
FT   CDS             12655..13047
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.22, probable pseudogene fragment, len: 130
FT                   aa; similar to part of hypothetical membrane proteins from
FT                   several organisms eg. M. tuberculosis MTCY359.31 TR:P95166
FT                   (EMBL:Z83859) (76.9% identity in 130 aa overlap)"
FT                   /db_xref="PSEUDO:CAA15454.1"
FT   CDS             13150..13329
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.23, probable pseudogene fragment, len: 59
FT                   aa; similar to part of hypothetical membrane proteins from
FT                   several organisms eg. M. tuberculosis MTCY359.31 TR:P95166
FT                   (EMBL:Z83859) (74.6% identity in 59 aa overlap)"
FT   CDS             13789..13926
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.24, probable pseudogene fragment, len: 45
FT                   aa; similar to part of M. tuberculosis hypothetical protein
FT                   MTCY359.32 Y0D3_MYCTU (MTCY1A11.03) (71.1% identity in 45
FT                   aa overlap)"
FT                   /db_xref="PSEUDO:CAA15456.1"
FT   CDS             13880..14404
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.25, probable pseudogene fragment, len: 174
FT                   aa; similar to part of M. tuberculosis hypothetical protein
FT                   MTCY359.32 Y0D3_MYCTU (MTCY1A11.03) (69.8% identity in 149
FT                   aa overlap)"
FT                   /db_xref="PSEUDO:CAA15457.1"
FT   CDS             14365..14466
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.26, probable pseudogene fragment, len: 33
FT                   aa; similar to part of M. tuberculosis hypothetical protein
FT                   MTCY359.32 Y0D3_MYCTU (MTCY1A11.03) (69.7% identity in 33
FT                   aa overlap)"
FT                   /db_xref="PSEUDO:CAA15458.1"
FT   RBS             14737..14741
FT                   /note="possible RBS upstream of glcB"
FT   CDS             14748..16943
FT                   /transl_table=11
FT                   /gene="glcB"
FT                   /product="malate synthase G"
FT                   /note="MLCB1788.27, glcB, malate synthase G, len: 731 aa;
FT                   highly similar to many eg. MASZ_ECOLI P37330 malate
FT                   synthase g (ec 4.1.3.2) (msg) (722 aa), fasta scores; opt:
FT                   1591 z-score: 3487.6 E(): 0, 56.9% identity in 731 aa
FT                   overlap. Also highly similar to M. tuberculosis glcB
FT                   MTCY1A11.06 (82.4% identity in 729 aa overlap)"
FT                   /db_xref="GOA:O32913"
FT                   /db_xref="HSSP:1N8I"
FT                   /db_xref="InterPro:IPR006253"
FT                   /db_xref="UniProtKB/Swiss-Prot:O32913"
FT                   /protein_id="CAA15459.1"
FT                   /translation="MTDRVSAGNLRVARVLYDFVNNEALPGTDINPNSFWSGVAKVVAD
FT                   LTPQNQSLLNSRDELQAQIDKWHRHRVIEPFDVDAYRQFLIDIGYLLPEPDDFTISTSG
FT                   VDDEITMTAGPQLVVPVLNARFALNAANARWGSLYDALYGTDTIPETEGAEKGSEYNKI
FT                   RGDKVIAYARKFMDQAVPLASDSWTNATGVSIFDGQLQIAIGTNSTGLASPEKFVGYNR
FT                   QLRSSNWSVLLANHGLHIEVLIDPESPIGKTDPVGIKDVILESAITTIMDFEDSVTAVD
FT                   ADDKVRGYRNWLGLNKGDLTEEVNKDGKTFTRVLNADRSYTTPDGGELTLPGRSLLFVR
FT                   NVGHLTTSDAILVDGGDGQEKEVFEGIIDAVFTGLAAIHGLKTGEANGPLTNSRTGSIY
FT                   IVKPKMHGPAEVAFTCELFSRVEDVLGLPQGTLKVGIMDEERRTTLNLKACIKAAADRV
FT                   VFINTGFLDRTGDEIHTSMEAGPMIRKGAMKNSTWIKAYEDANVDIGLAAGFKGKAQIG
FT                   KGMWAMTELMADMVEQKIGQPKAGATTAWVPSPTAATLHAMHYHQVDVAAVQQELTGQR
FT                   RATVDQLLTIPLAKKLAWAPEEIREEVDNDCQSILGYVVRWVDQGIGCSKVPDIHNVAL
FT                   MEDRATLRISSQLLANWLRHGVITSEDVRASLERMAPLVDQQNAEDPAYRPMAPNFDDS
FT                   IAFLAAQELILSGAQQPNGYTEPILHRRRREFKAQNR"
FT   RBS             17120..17126
FT                   /note="possible RBS upstream of MLCB1788.28"
FT   CDS             17138..19270
FT                   /transl_table=11
FT                   /gene="MLCB1788.28"
FT                   /product="hypothetical protein MLCB1788.28"
FT                   /note="MLCB1788.28, unknown, len: 710 aa; highly similar to
FT                   M. tuberculosis hypothetical protein Y0D7_MYCTU Q50597
FT                   MTCY1A11.07 (677 aa), fasta scores; opt: 2938 z-score:
FT                   3249.0 E(): 0, 66.0% identity in 714 aa overlap"
FT                   /db_xref="InterPro:IPR002035"
FT                   /db_xref="UniProtKB/TrEMBL:O32914"
FT                   /protein_id="CAA15460.1"
FT                   /translation="MGRHSMPDPEDSIDQPSNQFAASGPDQSDEIDHGYQSRMGYPEPV
FT                   FEPAATGSPSYRSYPHGAEHPADSTPEALDETIDYQSYWAEDRNEDLFVDGAADDHPDF
FT                   PPRPAGSSTSSQAPTSLSHLFKASHRSVGKWQGGHRSDGGRRGVSIGVIATLVAVVVLV
FT                   GAVIMWSFLGHILNNRKHQAAARCVGGHQTVAVVADPSIADYLQEFAQSYNASARPVGD
FT                   HCMMVTVKPVGSEAALTGFNDSWPANLGDKPALWIPGSSISAARLAVTADQKTISESHS
FT                   LVTSPVLLAVRPEFEQALANKGWAALPGLQTNPNSLADLNLPAWGSLRLALPMNGNSDA
FT                   TFLAGEAVATASVPAGAPAIQGVGAVRTLMSAQPKLADSTWAEAMSTLLKPGDVATAPV
FT                   HAVITTEQQLFQRGQSLSDAKSALGSWLPHGPAPVADYPAVLLNGSWLTQEQAAAASEF
FT                   ARFVQKPDQLAKLAKAGFRVNGVTPPSSSVTSFAAVPSTVSVGDDGMRATLVEEMIQPS
FT                   SGVAATIMLDQSMPTDEGGKTRLANVVAALDDKINAMPPTSVMGLWTFDGHKGQTEVTT
FT                   GQLADPVNGQPRSAALTAALDKQYSSNGGAVSFTTLRMIYQEMLANYHVGQTNSVLVIT
FT                   AGPHTDQTLDGARLQDFIRTSADPAKPIAVNVIDFGTDPDQATWKAVAQISGGSYQNLS
FT                   TSASLDLATAINTFLS"
FT   CDS             19296..19403
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.29, probable pseudogene fragment, len: 35
FT                   aa; similar to part of M. tuberculosis putative hydrolase
FT                   MTCY1A11.10 Y0DA_MYCTU Q50600 (286 aa) (62.9% identity in
FT                   35 aa overlap)"
FT                   /db_xref="PSEUDO:CAA15461.1"
FT   CDS             19402..19560
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.30, probable pseudogene fragment, len: 52
FT                   aa; similar to part of M. tuberculosis putative hydrolase
FT                   MTCY1A11.10 Y0DA_MYCTU Q50600 (286 aa) (69.2% identity in
FT                   52 aa overlap)"
FT                   /db_xref="PSEUDO:CAA15462.1"
FT   CDS             19928..20101
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.31, probable pseudogene fragment, len: 57
FT                   aa; similar to part of M. tuberculosis putative hydrolase
FT                   MTCY1A11.10 Y0DA_MYCTU Q50600 (286 aa) (50.9% identity in
FT                   57 aa overlap)"
FT   CDS             complement(20171..23029)
FT                   /transl_table=11
FT                   /gene="gcvP"
FT                   /product="glycine dehydrogenase (decarboxylating)"
FT                   /note="MLCB1788.32c, gcvP, glycine dehydrogenase
FT                   (decarboxylating), len: 952 aa; highly similar to many eg.
FT                   GCSP_ECOLI P33195 glycine dehydrogenase (decarboxylating)
FT                   (EC 1.4.4.2) (glycine decarboxylase) (glycine cleavage
FT                   system p-protein) (957 aa), fasta scores; opt: 2112
FT                   z-score: 3456.5 E(): 0, 53.5% identity in 956 aa overlap.
FT                   Also highly similar to M. tuberculosis gcvP MTCY1A11.11c
FT                   (84.7% identity in 942 aa overlap)"
FT                   /db_xref="GOA:O32915"
FT                   /db_xref="InterPro:IPR015421"
FT                   /db_xref="UniProtKB/Swiss-Prot:O32915"
FT                   /protein_id="CAA15464.1"
FT                   /translation="MSVPNSSNKQTCFTARHIGPNSEDVATMLAVIGVESLDDLAAKAV
FT                   PSDILDNVTDTGVAPGLDRLPPPATESETLAELGALARANTVAVSMIGQGYYDTLTPAV
FT                   LSRNILENPAWYTPYTPYQPEISQGRLEALLNFQTLVSDLTGLEIANASMLDEGTAAAE
FT                   AMTLMYRAARSTASRVVVDVDVFAQTVAVFATRAKPLGIDIVVADLREGLPDGEFFGVI
FT                   TQLPGASGRITDWTALIAQAHSRGALVAVGADLLALTLITPPGEIGADVAFGTTQRFGV
FT                   PMGFGGPHAGYLALHTKHARQLPGRLVGVSVDSDGTPAYRLALQTREQHIRRDKATSNI
FT                   CTAQVLLAVMAAMYASYHGAEGLTGIARRVHAQARALAAGLSAAGVEVVHQAFFDTVLA
FT                   RVPGRTVQIQGAAKERGINVWLVDGDHVSVACDEATTDEHITAVLAAFAATPARASFAG
FT                   PDIATRTSAFLTHPTFTKYRTETSMMRYLRALADKDIALDRSMIPLGSCTMKLNAAAEM
FT                   ESITWQEFTRQHPFAPVSDTPGLRRLISDLESWLVQITGYDAVSLQPNAGSQGEYAGLL
FT                   AIHDYHVSRGEPHRNVCLIPSSAHGTNAASAALVGMRVVVVGCHDNGDVDLDDLRIKLS
FT                   EHANRLSVLMITYPSTHGVYEHDIAEICAAVHDAGGQVYVDGANLNALVGLARPGKFGG
FT                   DVSHLNLHKTFCIPHGGGGPGVGPVAVRSHLVSFLPGHPFAPELPQGQPVSSAPYGSAS
FT                   LLPITWAYIRMMGADGLRTASLTAIASANYIARRLDKYFPVLYTGENGMVAHECILDLR
FT                   PITKSVGVTVDDVAKRLADYGFHAPTMSFPVPGTLMVEPTESESLAEIDAFCEAMIAIR
FT                   GEIARVGAGEWSVEDNPLRGAPHTAECLLASDWDHPYTREEAAYPLGKAFRPKVWPPVR
FT                   RIDGVYGDRNLVCSCLPVEAFV"
FT   RBS             complement(23037..23041)
FT                   /note="possible RBS upstream of gcvP"
FT   CDS             complement(23197..23892)
FT                   /transl_table=11
FT                   /gene="MLCB1788.33c"
FT                   /product="hypothetical protein MLCB1788.33c"
FT                   /note="MLCB1788.33c, unknown, len: 231 aa; highly similar
FT                   to M. tuberculosis hypothetical protein Y0DD_MYCTU Q50603
FT                   MTCY1A11.13c (225 aa), fasta scores; opt: 1313 z-score:
FT                   1787.2 E(): 0, 90.0% identity in 231 aa overlap"
FT                   /db_xref="GOA:O32916"
FT                   /db_xref="InterPro:IPR000551"
FT                   /db_xref="UniProtKB/TrEMBL:O32916"
FT                   /protein_id="CAA15465.1"
FT                   /translation="MTHLVTRARSARGNTVSEQPRQGQLDLADYRDTPTATTHGDIGLN
FT                   GPTAVSGPAQPGLFPDDSVPDELVGYRGPSACQIAGITYRQLDYWARTSLVVPSIRGAA
FT                   GSGSQRLYSFKDILVLKIVKRLLDTGISLHNIRVAVDHLRQRGVQDLANITLFSDGTTV
FT                   YECTSAEEVVDLLQGGQGVFGIAVSGAMRELTGVIDDFRGERADGGESIAAPEDELASR
FT                   RKHRDRKIG"
FT   RBS             complement(23896..23899)
FT                   /note="possible RBS upstream of MLCB1788.33c"
FT   CDS             complement(24125..24619)
FT                   /transl_table=11
FT                   /gene="MLCB1788.34c"
FT                   /product="hypothetical protein MLCB1788.34c"
FT                   /note="MLCB1788.34c, unknown, len: 164 aa; highly similar
FT                   to M. tuberculosis hypothetical protein Y0DE_MYCTU Q50604
FT                   MTCY1A11.14c (171 aa), fasta scores; opt: 1011 z-score:
FT                   1841.4 E(): 0, 95.1% identity in 164 aa overlap"
FT                   /db_xref="InterPro:IPR003729"
FT                   /db_xref="UniProtKB/TrEMBL:O32917"
FT                   /protein_id="CAA15466.1"
FT                   /translation="MGEVRVVGIRVEQPQNQPVLLLREANGDRYLPIWIGQSEAAAIAL
FT                   EQQGIEPPRPLTHDLIRDVIAALGHSLKEVRIVDLQEGTFYADLIFDRNIKVSARPSDS
FT                   VAIALRVGVPIYVEDVVLAQAGLLIPDENDEEVGGAVREDEVEKFKEFLDSVSPDDFKA
FT                   T"
FT   RBS             complement(24630..24634)
FT                   /note="possible RBS upstream of MLCB1788.34c"
FT   CDS             complement(24736..25491)
FT                   /transl_table=11
FT                   /gene="MLCB1788.35c"
FT                   /product="hypothetical protein MLCB1788.35c"
FT                   /note="MLCB1788.35c, unknwon, len: 251 aa; similar to M.
FT                   tuberculosis hypothetical protein Y0DF_MYCTU Q50605
FT                   MTCY1A11.15c (247 aa), fasta scsores; opt: 1397 z-score:
FT                   1097.7 E(): 0, 87.6% identity in 251 aa overlap"
FT                   /db_xref="GOA:O32918"
FT                   /db_xref="InterPro:IPR000551"
FT                   /db_xref="UniProtKB/TrEMBL:O32918"
FT                   /protein_id="CAA15467.1"
FT                   /translation="MSAPDSPALVGMSIGAVLDLLRSDFPDVTISKIRFLEAEGLVTPQ
FT                   RSASGYRRFTAYDCARLRFILTAQRDHYLPLKVIRAQLDAQPDGELPSFGSPYVAPRLF
FT                   SVTGGPGAGVGSGVGSDIPAVSPAGVRLSREDLLDRSGVADDLLTALLKAGVITTGPGG
FT                   FFDEHAIVILQCARALSEYGVEPRHLRAFRSAADRQSDLIVQIAGPIVKAGKAGARDRA
FT                   DDLAREVAALAITLHTSLIKSAVRGVLHR"
FT   CDS             complement(25488..25976)
FT                   /transl_table=11
FT                   /gene="MLCB1788.36c"
FT                   /product="hypothetical protein MLCB1788.36c"
FT                   /note="MLCB1788.36c, unknown, possible regulator, len: 162
FT                   aa; similar to hypothetical proteins from several
FT                   Mycobacteria eg. Y0DG_MYCTU Q50606 MTCY1A11.16c (162 aa),
FT                   fasta scores; opt: 888 z-score: 1502.9 E(): 0, 87.0%
FT                   identity in 161 aa overlap, and to the C-terminus of eg.
FT                   TR:P71484 (EMBL:U66560) embR regulator (384 aa), fasta
FT                   scores; opt: 189 z-score: 308.5 E(): 4.9e-10, 38.0%
FT                   identity in 92 aa overlap"
FT                   /db_xref="HSSP:1MZK"
FT                   /db_xref="InterPro:IPR000253"
FT                   /db_xref="UniProtKB/TrEMBL:O32919"
FT                   /protein_id="CAA15468.1"
FT                   /translation="MTDMDSGRQEDQTSDEVTVETTSVFRADFLNELDAPAQAGAESVV
FT                   SGVEGLLAGSALLVVKRGPNAGSRFLLDQAITSAGRHPDSDIFLDDVTVSRRHAEFRLE
FT                   GNEFHVVDVGSLNGTYVNREPVDSAVLANGDEVQIGKFRLVFLIGSKQDDDTGRTAGK"
FT   RBS             complement(25983..25988)
FT                   /note="possible RBS upstream of gcvH"
FT   CDS             complement(26220..26618)
FT                   /transl_table=11
FT                   /gene="gcvH"
FT                   /product="glycine cleavage system h protein"
FT                   /note="MLCB1788.37c, gcvH, glycine cleavage system h
FT                   protein, len: 132 aa; highly similar to many eg. GCSH_ECOLI
FT                   P23884 glycine cleavage system h protein (129 aa), fasta
FT                   scores; opt: 429 z-score: 686.6 E(): 4.3e-31, 49.2%
FT                   identity in 130 aa overlap. Contains PS00189 2-oxo acid
FT                   dehydrogenases acyltransferase component lipoyl binding
FT                   site and PS00017 ATP/GTP-binding site motif A (P-loop),
FT                   although the latter may be spurious. Also highly similar to
FT                   M. tuberculosis gcvH MTCY1A11.17c (79.1% identity in 134 aa
FT                   overlap)"
FT                   /db_xref="GOA:O32920"
FT                   /db_xref="HSSP:1HTP"
FT                   /db_xref="InterPro:IPR017453"
FT                   /db_xref="UniProtKB/Swiss-Prot:O32920"
FT                   /protein_id="CAA15469.1"
FT                   /translation="MSDIPSDLHYTAEHEWIRRSREDTVRVGLTDFAQSTLGDVVFVQL
FT                   PEVGAELAAGKSFGEVESTKSVSDLYAPVSGTVSAVNTDLEGSPQLVNSDPYGAGWLLD
FT                   VHVSDVGALESAIATLLDAETYRGTLTK"
FT   misc_feature    complement(26385..26474)
FT                   /note="PS00189 2-oxo acid dehydrogenases acyltransferase
FT                   component lipoyl binding site"
FT   misc_feature    complement(26448..26471)
FT                   /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
FT   CDS             complement(26643..26762)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.38c, probable pseudogene fragment, len: 39
FT                   aa; similar to part of M. tuberculosis hypothetical protein
FT                   MTCY1A11.18c Y0DI_MYCTU Q50608 (292 aa) (74.4% identity in
FT                   39 aa overlap)"
FT                   /db_xref="PSEUDO:CAA15470.1"
FT   CDS             complement(26753..27052)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.39c, probable pseudogene fragment, len: 99
FT                   aa; similar to part of M. tuberculosis hypothetical protein
FT                   MTCY1A11.18c Y0DI_MYCTU Q50608 (292 aa) (74.3% identity in
FT                   74 aa overlap)"
FT                   /db_xref="PSEUDO:CAA15471.1"
FT   CDS             complement(27051..27290)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.40c, probable pseudogene fragment, len: 79
FT                   aa; similar to part of M. tuberculosis hypothetical protein
FT                   MTCY1A11.18c Y0DI_MYCTU Q50608 (292 aa) (70.9% identity in
FT                   79 aa overlap)"
FT                   /db_xref="PSEUDO:CAA15472.1"
FT   CDS             complement(27500..27751)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.41c, probablb pseudogene fragment, len: 83
FT                   aa; highly similar to part of M. tuberculosis small basic
FT                   protein Y0DJ_MYCTU Q50609 MTCY1A11.19c (121 aa) (90.4%
FT                   identity in 83 aa overlap)"
FT                   /db_xref="PSEUDO:CAA15473.1"
FT   CDS             complement(28088..28261)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.42c, probable pseudogene fragment, len: 57
FT                   aa; similar to part of M. tuberculosis hypothetical protein
FT                   MTCY1A11.20c Y0DK_MYCTU Q50610 (307 aa) (70.0% identity in
FT                   20 aa overlap)"
FT   CDS             complement(28258..28500)
FT                   /pseudo
FT                   /transl_table=11
FT                   /note="MLCB1788.43c, probable pseudogene fragment, len: 80
FT                   aa; similar to part of M. tuberculosis hypothetical protein
FT                   MTCY1A11.20c Y0DK_MYCTU Q50610 (307 aa) (45.0% identity in
FT                   80 aa overlap)"
FT   CDS             complement(28839..29459)
FT                   /transl_table=11
FT                   /gene="MLCB1788.44c"
FT                   /product="phosphatidyltransferase"
FT                   /note="MLCB1788.44c, phosphatidyltransferase, len: 206 aa;
FT                   similar to many eg. PGSA_ECOLI P06978
FT                   cdp-diacylglycerol--glycerol-3-phosphate
FT                   3-phosphatidyltransferase (PGP synthase) (181 aa), fasta
FT                   scores; opt: 264 z-score: 212.4 E(): 0.00011, 30.5%
FT                   identity in 177 aa overlap. Contains PS00379 CDP-alcohol
FT                   phosphatidyltransferases signature. Also weak similarity to
FT                   M. leprae pgsA MLCB33.08c (27.3% identity in 143 aa
FT                   overlap)"
FT                   /db_xref="GOA:O32921"
FT                   /db_xref="InterPro:IPR004570"
FT                   /db_xref="UniProtKB/TrEMBL:O32921"
FT                   /protein_id="CAA15476.1"
FT                   /translation="MESVCPPNRVLTVPNLLSAVRLALIPAFVYVLLVMHADGWAVVIL
FT                   VFSGVSDWADGKIARLLDQYSRLGVLLDPAVDRLYMVTIPVVLALSGIVPWWFVVALLA
FT                   RDVLLTATLPLLWSRGLLSLPVTYIGKAATFSLMVGFPFVLLGTWDTLWSRVLGACGWA
FT                   FLIWGTYAYLWAFVLYVVQMTMVVRWMPKIKHQAHRQFAGKAR"
FT   misc_feature    complement(29229..29297)
FT                   /note="PS00379 CDP-alcohol phosphatidyltransferases
FT                   signature"
FT   RBS             complement(29469..29472)
FT                   /note="possible RBS upstream of MLCB1788.44c"
FT   CDS             complement(29521..31857)
FT                   /transl_table=11
FT                   /gene="secA"
FT                   /product="preprotein translocase seca subunit"
FT                   /note="MLCB1788.45c, secA, preprotein translocase seca
FT                   subunit, len: 778 aa; similar to many eg. SECA_ECOLI P10408
FT                   preprotein translocase seca subunit (901 aa), fasta scores;
FT                   opt: 619 z-score: 1759.4 E(): 0, 35.6% identity in 811 aa
FT                   overlap. Also highly similar to M. tuberculosis secA
FT                   MTCY1A11.22c (87.0% identity in 782 aa overlap)"
FT                   /db_xref="GOA:O32922"
FT                   /db_xref="HSSP:1M6N"
FT                   /db_xref="InterPro:IPR011116"
FT                   /db_xref="UniProtKB/Swiss-Prot:O32922"
FT                   /protein_id="CAA15477.1"
FT                   /translation="MSKTPRTQPGRLSSRFWRLLGASTDKNLNYSSAEVTAAAAYHKEA
FT                   ADLGDEQLRKACGLLNLNDLADSRDVPQFLAIVREASERSTGLRPFDVQLLGALRMLAG
FT                   DVIEMATGEGKTLAGAIAAAGYALAGRHVHVVTINDYLARRDAEWMGPLLEAIGLTVGW
FT                   ITAESTREDRKAAYGCDVTYASVNEIGFDVLRDQLVTDVDDLVSPHPDVALIDEADSVL
FT                   VDEALVPLVLAGATHRETPRLEIIKLVGELSAESDYDTDSDSRNVHLTDVGARKVEKAL
FT                   GGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYIVRDDAVHLVNASRGRIAQLQRWPD
FT                   GLQAAVEAKEGIETTETGEVLDTITVQALINRYATVCGMTGTALAAGEQLRQFYKLGVS
FT                   PIPPNTPNIRDDASDRVYITAAAKNDAIVAHLAEVHETGQPVLVGTRNVAESEELHERL
FT                   LRHGVPAVVLNAKNDAEEARFIAEAGKFGAVTVSTQMAGRGTDIRLGGSDESDHDRVVE
FT                   LGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVIAANLDRNKLPMQTD
FT                   EDGRIISLKTTGLLDHAQRVAEGRLLDVHANTWRYNQLIAQQRAIIVDRRNALLSSATA
FT                   REELAELAPKRYEELAQALPKEEAEERLETICRLIMLYHLDRGWADHLAYLADIRESIH
FT                   LRALGRQSPLDEFHRLAVNAFALLAADAIEAAQQTFETANILDGAPGLDLSKLARPTST
FT                   WTYMVNDAPLSDDTLSPLSLPGVFR"
FT   CDS             complement(31965..33611)
FT                   /transl_table=11
FT                   /gene="MLCB1788.46c"
FT                   /product="TPP-requiring enzyme"
FT                   /note="MLCB1788.46c, unknown TPP-requiring enzyme; len: 548
FT                   aa; similar to many eg. OCX_OXAFO P40149 oxalyl-coa
FT                   decarboxylase (ec 4.1.1.8) (568 aa), fasta scores; opt: 535
FT                   z-score: 720.7 E(): 5.4e-33, 31.6% identity in 563 aa
FT                   overlap and ILVB_ECOLI P08142 acetolactate synthase isozyme
FT                   i large subunit (562 aa), fasta scores; opt: 649 z-score:
FT                   601.7 E(): 2.3e-26, 27.5% identity in 541 aa overlap.
FT                   Contains PS00187 Thiamine pyrophosphate enzymes signature.
FT                   Also some similarity to M. leprae ilvB MLCB637.20 (29.1%
FT                   identity in 485 aa overlap) and M. tuberculosis ilvB
FT                   MTCY13E12.23c (26.5% identity in 551 aa overlap). Highly
FT                   similar to M. tuberculosis MTCY1A11.23c (86.1% identity in
FT                   548 aa overlap)"
FT                   /db_xref="GOA:O32923"
FT                   /db_xref="HSSP:1OZH"
FT                   /db_xref="InterPro:IPR012001"
FT                   /db_xref="UniProtKB/TrEMBL:O32923"
FT                   /protein_id="CAA15478.1"
FT                   /translation="MSTDPVLTHSIHAGRLVVRRLKASGVDTVFTLSGGHLFSIYDGCR
FT                   SESIRLIDTRHEQTAAFAAEGWSKVTRQPGVAVLTAGPGVTNGMSAMAAAQQNQSPLVV
FT                   LGGRAPALRWGMGSLQEIDHVPFVAPLARFAATAQSADAAGRLVDEALQAAVVAPSGVG
FT                   FVDFPMDYVFSMADDVGGGPGALANLPVAPAANPEALDRAAGLLAAAHRPVIMAGTNVW
FT                   WGHAEAALLRLAEECQIPVLMNGMARGVVPADHPLAFSRARGKALGEADVALVVGVPMD
FT                   FRLGFGKVFGSQTQLVVADRAEPDRDYPRPVAAGLYGDLPAILSALAGVGGTDSQDWIR
FT                   ALRTAETATRDLEKAELDDDRLPLHPMRVYAELASLLDRDAIVVIDAGDFGSYAGRVID
FT                   SYLPGCWLDSGPFGCLGSGPGYALAAKLARPNRQVVLLQGDGAFGFSGMEWDTLVRHNV
FT                   PVVSVIGNNGIWGLEKHPMEALYGYSVVAELRPGTRYDEVVRALGGHGELVSVPGELRP
FT                   ALERAFVTGLPSVVNVLTDPSVAYPRRSNLA"
FT   misc_feature    complement(32286..32345)
FT                   /note="PS00187 Thiamine pyrophosphate enzymes signature"
FT   CDS             33705..35621
FT                   /transl_table=11
FT                   /gene="MLCB1788.47"
FT                   /product="ABC-transporter atp-binding protein"
FT                   /note="MLCB1788.47, ABC-transporter atp-binding protein,
FT                   len: 638 aa; similar to many eg. Y0DO_MYCTU Q50614
FT                   hypothetical abc transporter atp-binding protein (639 aa),
FT                   fasta scores; opt: 3277 z-score: 4029.6 E(): 0, 74.9%
FT                   identity in 634 aa overlap. Contains PS00017
FT                   ATP/GTP-binding site motif A (P-loop) and PS00211 ABC
FT                   transporters family signature. Highly similar to M.
FT                   tuberculosis ABC-transporter MTCY1A11.24c (74.9% identity
FT                   in 634 aa overlap)"
FT                   /db_xref="GOA:O32924"
FT                   /db_xref="InterPro:IPR003593"
FT                   /db_xref="UniProtKB/TrEMBL:O32924"
FT                   /protein_id="CAA15479.1"
FT                   /translation="MELRPFYPSVNWGYALPDSLWWIAKAWAISAACVVVLVMLSFITR
FT                   WGRQYWRITRGYFIGPQSVGVWLMLAVLLFSVVISVRLNVLFSYQSKDLYNALQAAFEG
FT                   AGAQNDLVKQSGMHGFWMSLGIFSILAVIFIARVMADIYLTQRFIIAWRMWLTNHLTTD
FT                   WLDQRAYYREQFIDNTIDNPDQRIQQDIDIFTAGAGGTPNGPSNGTGSTLLFGAVESVI
FT                   SVISFTAILWNLSGRLAVFEFEIPRAMFWIVIVYVLLATIITFWIGRPLIGLNFANEKL
FT                   NAAFRYALVRLRDAAEAVAFYRGEEAERKQLEQRFTPIIDNYRRYVSRTIRFLGWNASV
FT                   SQTIVPLPWILQAPRLFAGKINLGDVGQTATAFGNIHDSLSFFRNNYAAFAAFRAAIIR
FT                   LHGLVVANARSRELPHVTAKSTNDGTVHVVAVEVRTSAGEQLIDPLDLQLNCGSSLVIT
FT                   GRSGVGKTTMLRSLAELWPYASGTLSRPDGKNETMFLSQLPYVPLGNLRGVVCYPNAPA
FT                   DIPEDTVRDTLTKVALNPLCDRLDEERDWAKILSPGEQQRIAFARILLTKPKAIFLDES
FT                   TSALDEGLEFALYQMLRSELPDCIIVSVSHRRAVELLHAQQLELLGGGQWRLGPVEKEP
FT                   LHV"
FT   misc_feature    35079..35102
FT                   /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
FT   misc_feature    35352..35396
FT                   /note="PS00211 ABC transporters family signature"
FT   repeat_region   35905..38304
FT                   /note="LEPREP repetitive element: 35905..38010 is 99.9%
FT                   identical to EM_NEW:MLCB2492 Z98756 Mycobacterium leprae
FT                   cosmid B2492 from: 32969 to: 35074. Whole region is 99%
FT                   identical to EM_NEW:MLB27CS L78817 Mycobacterium leprae
FT                   cosmid B27 DNA sequence from: 27332 to: 29731 (reverse)"
FT   RBS             36347..36350
FT                   /note="possible RBS upstream of MLCB1788.48"
FT   CDS             36361..37032
FT                   /transl_table=11
FT                   /gene="MLCB1788.48"
FT                   /product="hypothetical protein MLCB1788.48"
FT                   /note="MLCB1788.48, questionable ORF, len: 223 aa"
FT                   /db_xref="InterPro:IPR000169"
FT                   /db_xref="UniProtKB/TrEMBL:O32925"
FT                   /protein_id="CAA15480.1"
FT                   /translation="MMWSGSTWIHVRHEVLMIGMAVKVRDLRRRACRSRNGEAGAPWPW
FT                   VASGRGGIVLGPAWVLCGQHDLSGWGHRRSIVAAGLMTCSISCVTRRTLLVAFDWVTGN
FT                   YGANTAGVDARTGAHVEEIVEVAGCWTICGSSRSGCVEAGVGACRRGRFRADLPWIPPP
FT                   SGDLRDTIAEIHQYSTTSYRWVLYADIEVRCDSISHSALLERMLLPVKDKRVLGPGEGV
FT                   F"
FT   CDS             36782..37315
FT                   /transl_table=11
FT                   /gene="MLCB1788.49"
FT                   /product="hypothetical protein MLCB1788.49"
FT                   /note="MLCB1788.49, unknown, len: 177 aa; some similarity
FT                   to proteins from eukaryotic group II introns eg. TR:Q08724 
FT                   (EMBL:X71404) group II intron-contained hypothetical 66.6
FT                   kd protein (584 aa), fasta scores; opt: 220 z-score: 388.1
FT                   E(): 1.8e-14, 35.9% identity in 131 aa overlap. Also
FT                   identical to proteins from other LEPREP repetitive elements
FT                   eg. MLCB2492.31 TR:E337985 (EMBL:Z98756)"
FT                   /db_xref="UniProtKB/TrEMBL:O34698"
FT                   /protein_id="CAA15481.1"
FT                   /translation="MKLVLEPVVEAAFEPISPGFRPQAAISGTRSPKFTNTALQAIGGC
FT                   CMQTLRCAVTLSHILLCWSGCYCQSRINAYLVLVKAFSKAGVLTESGEHQNTHTGTSQG
FT                   NILSPVLTNIALPGLDEYRMQPWKPCGSMSTAYLPSRRRVTGLLSTTQSSRVADDCVVL
FT                   STWRPDTPEACKTK"
FT   stem_loop       37221..37274
FT                   /note="hairpin loop with 23 bp stem"
FT   CDS             37321..37638
FT                   /transl_table=11
FT                   /gene="MLCBB1788.50"
FT                   /product="hypothetical protein MLCBB1788.50"
FT                   /note="MLCBB1788.50, questionable ORF, len: 105 aa"
FT                   /db_xref="UniProtKB/TrEMBL:O32926"
FT                   /protein_id="CAA15482.1"
FT                   /translation="MLTPLGLQLSTAKTKTAHFGNWYGLSRLPHRVDTQEGNDHVGMSR
FT                   TCIADRARRSVKAKIRALANRKSQRNPGAVLAQINHRWFRALYRRRWKDIRRQFTTSEK
FT                   R"
FT   CDS             complement(38296..>39228)
FT                   /transl_table=11
FT                   /gene="MLCB1788.51c"
FT                   /product="cytochrome p450"
FT                   /note="MLCB1788.51c, cytochrome p450, partial CDS, len >
FT                   310 aa; similar to many eg. CPXK_SACER P33271 cytochrome
FT                   p450 107b1 (ec 1.14.-.-) (405 aa), fasta scores; opt: 595
FT                   z-score: 1026.7 E(): 0 42.2% identity in 313 aa overlap.
FT                   Also similar to several M. tuberculosis cytochrome p450's
FT                   eg. MTCY180.38 (42.3% identity in 317 aa overlap)"
FT                   /db_xref="GOA:O32927"
FT                   /db_xref="HSSP:1GWI"
FT                   /db_xref="InterPro:IPR017973"
FT                   /db_xref="UniProtKB/TrEMBL:O32927"
FT                   /protein_id="CAA15483.1"
FT                   /translation="TRLRKLVSKAFAPKVVQALEGDIAALVDSLLDKGAAAGQFDVIAD
FT                   LAFPLAVAVICRLLGVPYEDAPEFGRVSALLVQSVDPFITITGEPPEATEERLRAGVWL
FT                   RDYLEQLVKCRRGTPGEDLISRLIELDESGDQLTEEEIIATCGLLLVAGHETTVNLIAN
FT                   AVLAMLRNPSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQTTLTEGDT
FT                   MVLLLAAANRDPAVYSRPDEFDPDRPSSRHLAFAVGSHFCLGAALARLEATVTLSAISA
FT                   RFPQVQLAGELVYKPNVAMRGMSALPVQV"
XX
SQ   Sequence 39228 BP; 8450 A; 11975 C; 11332 G; 7471 T; 0 other;
     cattcggatc gagcgacggc gcattgggat cacctggttg ggcttcggac gagacagggg        60
     cgcctggaag gggtgtaatg atctcctgcg caggtgaggg agctgccgta gccgtcgatg       120
     gcggcagggg cgcgggatcg gcgttggcgg ccgcaggcaa cggcatcgta aaggcactgg       180
     cgctggccac cacggcaatc gccagtatcg cccacaatcc tttgcgatgt gtcgagtcca       240
     ggtcaacctg attcatggcg acgaacctac cgtgttacta ctgcgacgca aggacggctt       300
     gcttatgtgc ggtgggggtt ttccggtttg ccagttcgag acgtgccggt tcacgattgg       360
     acgcatcgct gcagcgccga gtacaacgcc actttatgag ctttgacatt gacccacaca       420
     cgctcttcgg gcatcagccg taactcccgt gttggcgtcg acgatgattt ccgcggccag       480
     gctaagagcc ccataaggtt gcttcggacc gcgaaccaag gacaagcgag tccccctccc       540
     cccgccccga ggtatctaat gccaccacag taagttcgac ggtagtgcgt gggctgtcca       600
     tgcgacgaat cgcactgaac ggcaaccgcg gtaggcgcga acacagcggc tgcgaaccgt       660
     cggtaccgac ggttccattg accagtttga cgcctgcgat ccaggcgccg caatgattgc       720
     acgacgcacc aagcagatcg gcgaccttcc cgatcgcgga aatcctgccg gactcaagta       780
     ctagcattca gatcggccat ggtgaccaca tacaacagct ggtgggttac caggatgatg       840
     gcgcagccgc ttcggggtta gccgggctgc gcaacaccgg gcggatagca gtggccacgg       900
     ccacatcaag cctagttagc ggctcgtcga ggagtagaac ctccggttgg gcagccaatg       960
     cgcgtacaat aacgacccac tgcgtttgac cacatgacag ttgccatggt ttgcggtcgg      1020
     cgccctgctc agctgttcac ctggagcagc caaccctagc gccttacccc gatagatata      1080
     tgccttaccc cgatagatat atagagcctt gtcctggacg ccgacggtcc gtagcatgct      1140
     taacatcttg ttatggctgc gcggtccgaa agccacgttg gccgtgacag tcatgaatgt      1200
     gcgttaacag caacggatac tgcaaaagca acccggcccg acgatcatgc gttgccacat      1260
     tcaccccggc tgcagtgtcg gtcaacacgc ggtcccccaa gcgcaccaga cccactacgg      1320
     ggcaaacagg ccggcgataa cttgcagggc ggtggacttg cccgcacctt tggctccaag      1380
     tacggcaagc acctcgcccg gaactaccga gaactcgaca ttcagatggc agtctgtcac      1440
     gaccggcgga agctgtaact cgctcacagt ggctacctcg tatcggccaa ggtcattccg      1500
     cgaacaacca agcccaggac caccagcgct gcccctacca caagcaggat cgacagtgcc      1560
     acagccgggt ccgcgtcggt cacccgctgt agttagattt cgagcggcgg cgtgcgagtg      1620
     actccttgcc gggagccggc aaggagttca gtgtcgcgcc aaactccccc agcgaaaggg      1680
     caaatgccat tactgccccg acgccatccc agacagtagc gacaacgtga cccaccacca      1740
     gacggtgttg ggtcgcgccc cgcgcataac cgccaccaca ttcatattca taagcgacca      1800
     cattcatatt cataagcggc tccaacgata cgggcaacat ctccgtggga gatccccaga      1860
     aacgacaacg aaatgaaagt gtgcgccatc accacagcag tcttgttgaa cgctatgcta      1920
     atgtcggagg cttgcaaaca acgcccgatc aatccgagtc ggccgaatgc attagagcaa      1980
     cgcaatgcca ctaaccacgg gggcaacacc agcggcagca gaatcagcag tcgcagcaac      2040
     cgcacaagcc gtgccgcgca gcgagccagt atcagctatg gtcacccgag cagcacacac      2100
     agcacggtgc tcgtgacaac ggtctccagg ctcagcaaca gtgccgtctt cgataaaaag      2160
     ctggtgatca acgaccagaa attctggcta gtccacctcg atcgctatcg ccaacaggag      2220
     caatgccaca aagacggtcc ccgctgcggc ggggacatat gtaccacggg aacatcggtg      2280
     cactttggtc gtcaaagttt gactaagccc gactgggcca gaatttgctg acctgcctca      2340
     cccatgaaca tcgcctggag acttctgcac cagcgtgggt aaaggcacct tcttgagcac      2400
     cgcaatggag taaacattca ctgcaacggc aacctccagg aaagttgatg gtggtcccct      2460
     tgcctgcgac actgcgcgcg tcggtaccat agactaacgg gacgtcggtc tgtccggtgg      2520
     tgaatcttgt taagggcatc ggtcacgctt gggttcttca ccgactgatt agttaagtgc      2580
     acgccgatga cgtcttcgat gcactgggtc gatgacccac atggcactgg ctgccgacca      2640
     caccaccacg ctgaactacg gcttagccag gttcggcgaa ggatcccgat cttttcggat      2700
     tgcccaccac agtcacgatg accaacgtgt tcgaggtaaa ggtttgtcga tgtgctaacc      2760
     aataatcgga ccttggcgac agtgtccatc tgcgtggtgt ccgcgcgttc gcgccttggg      2820
     gcaactgggt cgaaagctcc tagcaacccg cgaactcgac gtcgacgctg acacccggat      2880
     tgtctgcttt gaactggctg ctgatctgcg taaacgcaga ctcgagcaga gccgcggcga      2940
     acaccacaaa ctacctggaa atttggggta gctgggatgg tgacgacgag tgcgagttcg      3000
     aactgcacgc cgctgttcca gctagcaatc cacccagcag catcgtcgat accaaaccgg      3060
     cgagcacccc gaagcgggct agggttcacc caacttgtgt agggcttccg gtgattcgga      3120
     atttcgctca gtagctccag tggttactgt ttagtaacat ttaagcgaga tggacgccac      3180
     aacacgctga gatactcggc aacgatccga tgccactatc ctagagccaa gttcgccgcg      3240
     ccgagtgcaa agtataggtg ccgttaacct gccagggtct gcgttcagcg gtgaacacga      3300
     ggaggtcatg gcagtggatg tgctggttac tgggggcaac accgatctgg ggcgcacaat      3360
     cgctgaaggt tttcgcaacg acggtcacaa ggtgaccctc gtgggtccgc gccgagccga      3420
     cctcgaggtc gtcgccaagg agctagacgt ggacactatt gtctgcaaca ctaccgatcc      3480
     agccagcctc gatgaagccc gcggattgtt cccccgtcac ctaaacacca tcgtcaatgt      3540
     tccgacgctg ggctttgata ccggagaccc acgcactttc tcactatccg atacagccaa      3600
     tgcctggcac aatgagctgg acgcgacggt gctctcggcg gtgctgacgg tacagtccgt      3660
     tggtgatcat ctgcgctccg gcggttcgat catcggcgtg ctggcggaaa acccgccagc      3720
     gggcagtgtc gacgcagcca tcaaagccgc actgtcgagt tgggtggccg gccaggcggg      3780
     cgttttcggc actcgtggca tcacggtcaa tgccatcgcc tgtggacgta gcgttcaagc      3840
     cggatatgaa ggcctttcac gcatgcctcc gcacgtcgca acggaaatca cccggttagc      3900
     gttgttcctc actaccccgg cgtctcgcca catcaccggc cagacgctgc acgttagcca      3960
     cggcgcgcta actcattttt aactgaaaaa ctctgtgagc ttagttaaaa cggttagccc      4020
     atagccacag gatacactgt ggctattcgc ttggtctgca gatccccact ttgaactgct      4080
     acccggggga gaaagttttt acgacggtca tcgcccaagc acacgatgcc gagccggctg      4140
     gattcgactt gactttagtc aagtcatggg ccaaattcta ccaactaccc aatgttaggc      4200
     tcacccaccc aaccaatgtt cgaggcctaa caccaccctc aacaccttca gcgcgctggc      4260
     tattatctgc caaacgcgtg caagctgggc gctttggtag ccggcaacac ctaactgcaa      4320
     ggcaatccct gctgaccaac gtcatcacca cactaacact ggatttggtc agcagagccg      4380
     ggcgatttta ggcatcggca ccgactagtt cgagctcgag catgatcaac ttcggcctcg      4440
     aattcagcac cctcgccgat aaattcaacc ggctcgacga agtgttacag attcatctta      4500
     ttcatcctgc caataatcaa gaacgatcca cccggcttct cgggcaactg ctaccacaac      4560
     caatgaggtg ctggccaatc ccccccttcc gcgaccacat tccgctgatg gtcggcggca      4620
     gcggtgagaa gaaaacgatc ccgcttgccg cacgacactt caacgttatc gccgggttcg      4680
     acgcactaca aggcaaggca aggtgcaaat gatgcggcgg cagtgtgagg aaaatcggcc      4740
     acaatccggt gacgctggaa atcaacacgc tgatcacagc cattattggc aaaaacatga      4800
     aagtcgacca aatcccctcc gagatgactc aacgaatgga gataggcaac accgagccta      4860
     tcgcctaccc gatccaggcc aaggtcctcg acgcgggaat cgaaagtctg aagtatcaat      4920
     atgcccagct acacgccggg tagcatcaac aaagctggca aagcgctgca tacgctagtc      4980
     ggcctgccgc gggggtgccg catcggcgcg gccatcaagc ttgtcacgtc accgtgacca      5040
     caggtagctt actctgccgg tgtggctaat tgcacacact cccacctgag attctggaga      5100
     gcagcttgac taccttagta cttagtagct aactgcagtc accatcacgg agtcccgtca      5160
     ggagcagcgg aacatgaatg cccagccagc agccacagct gctcaggacc gccggcatca      5220
     agtcgtcatc atcgggtcag gatttggtgg tctgaacgca gcgaagaagc tcaagcgagc      5280
     caacgtcgac attaagttaa tcgcccgcac cacccatcac ctattccagc cattgctata      5340
     ccaggtggcc accggcatca tctccgaggg ggaaatcgcg ccgccgaccc gagtcgtctt      5400
     gcgtaagcag cgcaacatcc aagtgctgct cggcaatgta acccacattg acttagctaa      5460
     ccagtgcgtc gtgtcggagt tactcggtca cacctatgaa accctctatg acagccttat      5520
     tgtcgcggcc ggagctggcc agtcgtactt cgggaacgac caattcgctg aattcgcacc      5580
     cggtatgaag tcaattgatg acgcgctgga gttgcgtggg aggattttga gcgccttcga      5640
     gcaggccgaa cggtcaaacg atccggaacg acgagagaaa ctgctaacat tcactgtggt      5700
     tggagccggc cccaccggtg tcgagatggc tgggcaaatc gccgaattgg ccgaccatac      5760
     gttgaaggga gccttccgtc gcatcgactc aaccaaggcc cgggtagttt tgctcgacgc      5820
     tgcccccgcg gtgttgccgc cgatgggcga aaaactaggt cagcgtgcgg ccgctcgatt      5880
     gcagaagatg ggcgtggaga tccagctgag tgcaatggtc acagatgtgg accgcaatgg      5940
     cattacagtc caagactccg atggcacagt ccggcgcatc gaatcggcct gtaaggtgtg      6000
     gtcagcgggg gtctcagcaa gccggctggg aagagacctt gccgagcagt ccttggttga      6060
     actcgactgg gctggccggg tgaaagtgct gcccgatctg tccatccctg gatatcgaaa      6120
     cgtgtttgtg gtcggtgaca tggccgccat cgacggcgtg cctggagtcg cgcagggtgc      6180
     tattcagggc gctaaatacg tggcaaacaa cataaaggct gaactcggtg aggccaaccc      6240
     agccgaacgc gagccgtttc agtacttcga caagggctcc atggccacag tgtcacggtt      6300
     ttccgcggta gccaagatcg gtccgctaga gttcagcggc tttatcgcct ggctgatgtg      6360
     gttggtgctg catctgatgt acttaatcgg cttcaaaacc aaaatcacca cgttgttgtc      6420
     gtggacggtg acttttttga gcactcggcg aggtcagctg accattaccg agcagcaagc      6480
     tttcgcgcga acgcggctcg aacagctggc agagttgact gccgaatctc agagtacagc      6540
     ggcagctaac agggccacca tgcgggcgag ctagacagtt aacctgtccc cctgattagc      6600
     tgtgagcagc caagcttagc tgtcgttgga caggtcctgg aatctccacc tggccgcagg      6660
     tcaccctcgt gttcggtgtc gttggctcag tgtgactagc cataactagc tgacgccggc      6720
     tgcgatggat tggtggtgta cgccacccca gaaccgatga tggagcgaag gaaatcaata      6780
     ttgttgacac ccaagcacat ttccgcagct gcagcaacta ttgagccagg tgtaggccgc      6840
     catgctgatc atgctttggc atgatcagca gtagacaccg ccggacacga ggaccatcag      6900
     tcttgcaata gcttgggctt cacctcgaac tggacgcagg cgtcatcgag gctaattcgg      6960
     tgaactgcag ccccaacgcg ctgtcaaatg gtgcgttagt gctcaaactt ttcggtacat      7020
     cgacccgtgt ctacatcatc accggatcca cctatgcgca tcaaagcaca accaacagat      7080
     actggagttg tccaggcaga caatgtagcg agtcaaccga gggtcacggc cgccctcagg      7140
     acaccagcac tgtcattgcc gctcgaccag ccaaaaatag gcaaggctgc cctaatttag      7200
     caaaagttgg gtgtgagtca cgacgataga tctcgatggt ggccactgtt aatagtgtca      7260
     cattagagtc ctagacagct gatctactaa atcacgtctg tcgaccgccg actcggctac      7320
     cgccgggccg acggcaaccg acttggatac gacaatcggt agtaatccgg agtaagctgg      7380
     cttcaacgct caggagatga acgaactatg gccaagctga cgcggctggg ggatttagaa      7440
     cgtgccgtga tggatcattt gtggtccaga caagaacccc aaacagttcg tcaggtccac      7500
     gaagcgttgt cggcgcgacg cgacctcgcc tacacgactg tgatgaccgt gctgcagcga      7560
     ttggctaaga agaatctggt ctcgcagatt cgtaacaacc gggcccaccg atacgcgccg      7620
     gtgcatggcc gggacgaact ggtggctggc ttaatggtcg acgcgctgga ccaagccgag      7680
     gattccgata gcaggcaagc cgcgcttgtg cacttcgtcg agcgggtcgg ggccgacgag      7740
     gcggacgcgc tgcgacgcgc acttgcagaa ctggaaacac atcaacgcca tgtccgtcat      7800
     ctggtggcac tccagcggac aactgaggga gactagcagc gtgtccgcac tggcctttac      7860
     catcctcgcg gtgctgctgg ttggccccac accgacctta gtagcacgtt cgacatggcc      7920
     gttgcgcgct ccacgcgccg cgatggtgtt gtggcagacc attgctctgg ccgcggcact      7980
     ttcgacgttc agcgccggca ttgcgatcgc cagtcgggtg ctcatgcccg gccctgacgg      8040
     gcggctcact gccagcgtta tcggcgccgc cggccggctc ggttggccac tgtgggcggc      8100
     atacgtcgcc gccttcgcgc tgacagtgct agtcggtgca cggctgatcg ttgcgatagt      8160
     gcgggtggcc atcgccacac ggcggcggcg ggcccaccac cgcatggtgg tcgacctggt      8220
     cggggtcgga cacaatgcgg ccctcgcgca gccgtgcgcc cgcgcgcgcg accttcgagt      8280
     cttggaggtg gcgcaaccac tcgcctactg tctgccgggc gtgcgtagcc gagtagtggt      8340
     cagcgaaggg gcgctgacca agctgaacga cacagaagtc acggcgatcc tcacccacga      8400
     acgggctcat ctgcgtgccc ggcacgactt ggtgttggag gcattcaccg cggtacatgc      8460
     agcctttcca cggctggtcc gtagctccgc cgcgctgagt gcggtgcggc tactcgtcga      8520
     gctgctagcc gatgacgccg cggtacgtgc tgcggggcgc actcccctcg cccgggcatt      8580
     agttgcttgt gcgtccggtc aggcgccgtc aggcgcgcta gccgcgggtg gcaacaccac      8640
     cgtgctgcgt gtacgccgac tgtcggggcg aagcaacagc gcggtggtgt ccgcagccgc      8700
     atatttggcc gcggcaatcg tattattagt gcctactgta gcgctagccg taccgtggct      8760
     gacggagcta caacggctgt tcaatattta acccagtctt agcgcaaacg ctgagcgaaa      8820
     aaccttatgg atgaccacaa gtacgctatg ccacagtgtg ccggaatagc gttggcgaca      8880
     atttgccgca caagttctcc aacctgagag gcgcaaagga gatgcaggac atgagtgcgc      8940
     cggaatcgaa gacggccatt gcgcagatcg gcgtcaccgg gctagccgtg atgggttcga      9000
     acatcgcccg gaatttcgcc cgacacggct ataccgtggc gttgcacaat cggtcaatcg      9060
     ccaagaccga cacactgctc aaagagcacg gatccgaagg gaatttcgtg cgaaccgaaa      9120
     cgatccccga gttccttgcc gcactacaga ctccgcgacg ggtgctgatc atggtaaaag      9180
     ccggtgacgc caccgatgcc gtcatcaatg aactcgccga tgttatggaa cccagcgaca      9240
     tcatcatcga cggcggcaat tcgctgttca ccgacaccat tcgccgcgaa aaagcaatgc      9300
     gtgagcgtgg cctgcacttc gtcggcgccg ggatctccgg cggcgaggag ggtgcactga      9360
     acggaccgtc gatcatgccc ggcgggcccg ccgaatcgta tacctcgctg ggcccgctgc      9420
     ttgaggagat ttccgcgcac gtcgacgggg tgtcgtgttg cacccacatc gggccaggcg      9480
     ggtcgggcca cttcgtcaaa atggtccaca acggcatcga gtactccgac atgcagctca      9540
     ttggcgaggc ctaccagctg ctgcgcgacg gattgggcat gagtgcaccg caaatcgctg      9600
     acgtgtttac cgaatggaac aggggcgatc tgaacagcta cttggtagag atcaccgctg      9660
     aagtgttgcg ccagaccgat atcaagaccg gcaggccgct ggtcgatgtc atcctcgata      9720
     aggccgagca aaagggtacc ggccggtgga ccgtacagtc cgccctggac ttgggcgtgc      9780
     cgataactgg aatagccgag gcggtgttcg cgcgcgcgct gtcgggttcg gtgctgcaac      9840
     gcaaggccgc catcgggctg gcctccggca agttgggcaa caaacccaca gatcgcgaga      9900
     cattcatcga agacgtacgc caggccctgt atgcctccaa gattgtggcc tacgcgcagg      9960
     ggttcaatca catccaaacc ggtagtaccg agttcggttg gaacatcaca ccgggtgact     10020
     tggcgaccat ctggcgcggc ggctgcatca tccgggcgaa gtttctcaac cgcatcaagg     10080
     aagctttcga cgccgccccc gacctggcca gcctgatcgt tgcgccgtat ttccgcagtg     10140
     ctgtcgaatc ggcgattgac agttggcggc gtgtggtgtc cacagctacc cagctaggta     10200
     tcccaaatcc cggcttctcg tccgcgttgt cgtactacga tgcgctgcgc accgagcgac     10260
     ttccggccgc actgacccag gctcaacgtg actttttcgg cgcgcacagc tacggacgcg     10320
     tcgacgcgcg gggcaaattc cacacactat ggagtgaaga ccgtagcgaa gttacggtct     10380
     agttggccaa gctaagagac atccggtggc cccacactaa atacaaaatc ttttagagtg     10440
     aaacgagagc gatgaggttt ctggacgggc accagcccag gttcgaccta acctataaag     10500
     acgttttcat cgtgccacac cggtcggatg ttgcgtcgcg atttgacgtc gatttgtcaa     10560
     cctatgacgg ctccggcacc actattcccg tagtggtcgc caacatgacc acggtggccg     10620
     ggcaacggat ggcagagacg gtagctcgcc ggggcggctt agtaatttta ccgcaggatc     10680
     tgccgattgc aacagtgcag caggcagtgg agttcgtcaa gagccgtgac ctggttatcg     10740
     ataccccggt gttactgaca cctaacgatt cggtgtccga cgcgaccaca ctgatccaca     10800
     agcgcgcgca cggtgttgcg gtggtggcct tcgaaggccg cccaattggt ctggtgcgcg     10860
     aatcgtcttg cctaggtgtg gaccgcttca ctcgggtgcg ggatgtcgcg actaccgact     10920
     ttgtaaccgc cccggtgggc accgatccac gcaagatctt cgacctgctc gaacatgccc     10980
     cgatcgacgt cgcggtgctg actaacgccg acggcacgct ggccggagta ctgacccgca     11040
     ccggggcgat ccgcgccggc atctacaccc cagccaccga tgcccgcgga cggctccgca     11100
     tcggtgctgc tgtcggcata aacggcgatg tagccggcaa ggcccagtcc ctcgccgagg     11160
     caggtgtcga tgtgctggtc gtcgacaccg cacacggata ccaagtcaag acactcgagg     11220
     cgatcaaatg cgtcgcatcg ctgaacttgg gtgtgccgtt ggtcgcgggc aacgtggtgt     11280
     cggctgaagg tactcgcgag ctactcaacg ccggggcgac catcgtcaag gtcggcgtcg     11340
     gcccaggagc aatgtgcaca actcggatga tgaccggtgt tggccgaccg caattctcag     11400
     ctgtactcga atgtgcctct gctgcaagga aactcaatag gcacgtgtgg gctgatggag     11460
     gagtccgcca tccgcgtgac gtggcgctgg cgttggccgc aggagcatcg aacgtgatga     11520
     tcgggtcgtg gttcgccggg acttatgagt cacccgggga cctcatgcgg gaccgccacg     11580
     accaaccgta caaggaaagc tacggcatgg cgtccaagcg agcggtggtt gcccgcaccg     11640
     ttgccgacag ctcattcgat cgcgctcgca aggcgttatt cgatgaaggc atctcgacct     11700
     cacggatggg gctggatccc gaccacggtg gtgtcgagga cctgatcgat cacatcacct     11760
     ccggcgtgcg cagcacctgc acctatgtcg gcgcgtcgac cctggcggag ctgcatgaga     11820
     aggctgtcgt cggggtgcag tcagcggcgg gtttcgccga gggccatcca ctgccctcgg     11880
     ggtggtgaca cctgacctcg gcgaaagtcg ctacgatgtg aacttctgga tttcagggca     11940
     cacagcaatg tgcgctgctc cgtggcccaa accgttgaag agcgaaaggg acgacgtgcc     12000
     gcaggcaccc gttgaagccg ttggctcccg ggtcgagcag ccacccgcat cgttgtcggc     12060
     tcctccagca tcgcgaaaac caagcatgtc atgaacgtag ccgtcactgt gtgcagcttg     12120
     ttggccatcg ggttgctcat tttcgagcaa cgcggtgttc gtcgcggaga aattatcgtt     12180
     gaccgccctg gaccgcagca cggtcaaggc caatgctcgc agcggtaccc gccaggatcg     12240
     ctgtattctg cacgcccaac acaagttgtc gttccagctt tcgggaactc agttgggtat     12300
     ctcaatcacc actttggcaa cgggttacct gaccgaaccg atgatggccg acctaccgca     12360
     tccggcgtta aacgcgatcg gaatacctga ccgagtagcc gactggatca ctacctgctt     12420
     ggtgttggtg attgtcacgt cgacgtcaat ggtgttcggc gagctggtat cgcagtatct     12480
     cgccgtagcg cgtccgctgc gcaccgcccg cactgtcgta ggcgtgcagc tgctgctcac     12540
     tccagccatt cgattgacca actgggcagc gaactgcatt gtgcacaacc tgggcatcga     12600
     accggccgag gagctgcggt ctgcccagtc accgcaggaa actgctagca tctgatgcaa     12660
     acctcggcgc gcaacggcgc cctggacgcc accacggcgt cgctggtgag acggtcatta     12720
     cagttcagca ccctgactgc cgcggaattg atgacgcccc ggtccacaat cgtggcactg     12780
     caaaccgacc acactgtcag cgacctggtt gcgaccgccg ctgcgtccgg gttctcgcgt     12840
     ttcccaattg tcgatggtga cctcgacgca actgttggca ttgttcacgt aaagcaggtt     12900
     ttcgaagttc catccgccga tcgcgctagc acgctgttga ccacagtcgc aaagccagtc     12960
     acggttgtgc cgtcaacgct ggacggcaat gcggtgatgg cgcaaatctg cacggatagt     13020
     ctgcagaccg cattggttgt cgactagtac ggcagcactg ccggtatgtt aactgtcgag     13080
     gatttgatct aagaaaatcg tgagcgattt ccgcgacgaa tatgacgacg ccaccccaga     13140
     cgtagtggcg gccggcaggt atcgggtttg ctgcgcattg acgaggtggt cagcgccatc     13200
     ggatatcgag cctccgaagg gccataggaa aagattggta ggctcgtgct ccggaagctc     13260
     ggtcacattc cggtagttgg ggaaacggtg gagctggccg ccttagacgc aaatggcctg     13320
     gcggacgcag gcacggcaag ccgcccgtgg tccagatgga cagccgtcgg atcgacttgc     13380
     ttgcgctgac taagcggggc aattaaccgg gcgattatca caaatccagc ctaggactgg     13440
     gctgatgcaa aacattctgg tactgctggc ggctaccgtg ctaatcggaa ccaaacgcgt     13500
     ttttcttcgg cgcggaattc tcgctgatct cagccccgtc gcgaccgcct tgaagcgttg     13560
     accgaacagg gcagaacgag cggaatcatc gtgatgcgcc agcgagcagc tctcgtctat     13620
     gctggcagga gctcaactag ctgtcaccgt aaccctcgat actgctcgcc aagattagcg     13680
     aggcggcagc gaccaagctg ttgcggacat cgtgtcagct gaccggtacg tcacctccgc     13740
     tgctgcacat cctgtcgctg gtgattacgt tggcgctgtt ggtcgcccct acatgtgctg     13800
     ttcggcgagg tagtacccaa gaatatcgcc ctggccgatc cggaacgaac agcaacgttg     13860
     ctattaccat tctgcctgat ctacgtgcgt gctacccaac cgttcattgt tctctacaac     13920
     aacatgcacc aacgcggtat tgcgcgggct gggcgtagag tcgaaagacg aactcgacat     13980
     cacagtttcc acagccaagt ttagcgagat gatttccgaa tcggtatcaa agggtctgct     14040
     ggatcaagaa gaacacaagt ggctgacgcg agcactgcag attcgcacta gagtggtcgc     14100
     cgatgttgca cggctgcttg ctgatatccg agcagtgccg gtagcgacag ccggctgtag     14160
     ctcaactgtt gacgcggtcg aacgggccct agcccaaacc ggctattatc ggtttccggt     14220
     tgttggtctc gacagcgagt tcgtgggata tctgcacata aaggatgtgt tgacgctcgg     14280
     cgatgatccg cagaccgtga tcgatctggc actcgtacgt ccactgcccg aggtgcccga     14340
     atcactgccg ttggccgatg cttttcgcag atgtgtcgca gcaacagcca tctggcactg     14400
     gtgactgccg atggtggcga ggtagtcgcg ttggtggcga tggaggatct agtgaacgat     14460
     ctacggcacc atgcacaacg ggacacactg aaactaagca ccgggtagag ccgccagcag     14520
     cccgtatgag ctttaattgt tacacctaac tagatcggtt aggtgtgtta tcaacacacg     14580
     tttcgcaaaa ccaagcctcg ggcgaccgat gaagctgttg acctgctgtt gcgggtcggc     14640
     cggaatacgc tcgtcaggct gttggccggt aggcttatgc gcgtagaccg tgagagccac     14700
     atcggggacc gttggggccg ccagtaagcc caatatggag gagaaccatg actgatcgcg     14760
     tgtcggcggg gaatttgcgc gtcgcccgtg tgctttacga cttcgtcaac aacgaagccc     14820
     tgcctggcac cgacatcaac ccaaacagct tctggtcggg cgtcgccaag gtcgtcgccg     14880
     acctcacccc gcaaaaccaa agtttgctga actcccgcga tgagctgcag gcccagattg     14940
     acaaatggca ccgccatcgt gtgatcgagc cattcgacgt ggatgcttat cggcagttcc     15000
     tcatcgatat cggctatctg ctgcctgaac ccgatgactt caccatcagc acctcaggag     15060
     tagacgacga gatcaccatg accgccggcc cgcagctggt ggtgccggta cttaacgcac     15120
     ggttcgcact caacgccgcc aacgcccgct ggggctccct ttacgacgct ctatatggca     15180
     ccgacaccat accggaaacc gagggagccg aaaagggctc tgagtacaac aagattcgcg     15240
     gcgacaaggt gatcgcctac gcacgcaagt ttatggatca ggccgtcccg ctggcttctg     15300
     actcatggac taacgctacg ggagtgagca tcttcgacgg ccagcttcag atcgccatcg     15360
     gcacgaattc caccggatta gccagtcccg aaaagtttgt cggctacaat cgccagttgc     15420
     gatcctccaa ctggtcggtg ctgttggcca atcacggcct gcacatcgag gtcttgatcg     15480
     acccggaatc accaataggc aagactgacc ccgtcggcat caaggatgtg atcctggaat     15540
     cggccatcac cacgatcatg gacttcgaag actcagtcac tgccgtcgac gccgacgaca     15600
     aggtacgcgg ctaccgcaac tggctcggcc tgaacaaagg tgacttaacc gaggaagtca     15660
     acaaggacgg caagaccttc acccgcgtgc tcaacgccga ccgcagctac accacgcccg     15720
     acggcggtga attgaccctg cccgggcgca gcctgttgtt cgtccgcaac gtgggccatc     15780
     tgacgaccag cgacgcgatt ctcgtggacg gaggtgacgg tcaggaaaaa gaagtgttcg     15840
     agggcatcat agatgcagtg ttcaccggtc tggccgcaat ccacggactc aaaaccggcg     15900
     aagctaatgg cccactgacc aacagccgca ccggttccat ctacatcgtc aagccgaaaa     15960
     tgcacggtcc cgcggaggtt gcgttcactt gcgagctgtt cagccgcgtc gaagacgtgc     16020
     tggggttgcc gcagggcacc ttgaaggtcg gcatcatgga tgaggagcgg cgtacgacac     16080
     tcaatttgaa ggcgtgcatc aaggccgccg ccgatcgggt cgtgtttatc aacactggct     16140
     tcttggaccg caccggcgac gagatccaca cctcaatgga ggccggcccg atgattcgta     16200
     agggtgcgat gaaaaacagc acctggatca aagcctacga ggacgccaat gttgacatcg     16260
     gactagccgc aggcttcaag ggcaaagcac agatcggcaa gggcatgtgg gcaatgaccg     16320
     aattaatggc tgatatggtc gagcagaaga tcggccagcc taaggcgggc gccaccaccg     16380
     cgtgggtacc ctcgcccact gcggccacgc tgcatgcgat gcactaccac caggtcgacg     16440
     tggctgccgt gcaacaagaa ctgaccggcc agagacgtgc caccgttgac cagctgttga     16500
     ccattccgtt ggccaagaaa ctggcctggg ctcccgagga gatccgcgag gaggtcgata     16560
     atgactgtca gtccatcctc ggttatgtgg tgcgctgggt ggaccagggt atcggttgct     16620
     cgaaggtgcc tgacatccac aatgtggcac taatggagga ccgcgccacc ctgcggatct     16680
     cgagccagtt gctagcaaac tggctgcgcc acggcgtaat caccagcgag gacgtgcggg     16740
     ccagcctgga acggatggcg ccgttagtcg atcagcaaaa cgccgaagac ccagcatatc     16800
     gcccgatggc gcctaatttc gatgacagca tcgcgttcct agcggcgcag gaactgatac     16860
     tgtccggcgc acaacagccc aacggctata ccgagccgat cctgcatcgc cgtcgtcgcg     16920
     aattcaaggc acagaaccgg tgacggatgc aggctgctgg cggccagctg tgagagcacc     16980
     accagccgcg ccgcggctaa ggacagaatc gggtccatct agatagaacc gctgccttac     17040
     gccagctcgg catacggtta tgtagtcgat gactaaactc ggcgccgagt tcaaaccaga     17100
     tcagacacgg atcaacagaa aggcggcgaa taccggtatg ggtaggcaca gcatgcccga     17160
     ccctgaggat tccatcgatc agccatctaa ccaatttgct gcatccgggc cggatcagag     17220
     cgacgagata gatcacggct accaaagcag gatggggtac ccagagcctg tttttgaacc     17280
     agcggctacc ggctcgccga gctaccggag ctacccgcac ggagcagagc atccggctga     17340
     ctccacaccc gaggctctcg acgaaaccat cgattaccag agttactggg cggaagaccg     17400
     caacgaggac ctttttgtcg atggtgcagc cgacgaccac ccagactttc ctccccgacc     17460
     cgcgggctcg tcgactagct cacaggcacc gaccagcctg tcgcacctat tcaaagctag     17520
     ccaccgtagc gtcggcaaat ggcaaggcgg acaccgcagt gacggcggac gacgaggggt     17580
     cagcatcggc gtgatcgcga ccctcgtcgc ggtcgtggtg ctagtgggcg cggtgatcat     17640
     gtggagtttc ctcggccata tcttgaacaa tcgcaagcac caggcagccg cacgctgcgt     17700
     aggtggtcac cagacggtcg ctgtcgtcgc cgatccgtcg atcgccgatt acctgcaaga     17760
     gttcgcccaa agttacaacg catccgcccg accggtgggc gaccactgca tgatggtgac     17820
     tgtcaaacct gtcggctcgg aggcagccct cactggtttc aacgacagtt ggccagctaa     17880
     tttaggggac aaaccggcac tgtggatacc gggcagctcg atctccgcag cacggctcgc     17940
     cgtgaccgcg gatcagaaga caatcagcga aagccattct ctggtgacgt cgccagtgct     18000
     gctagcggtt cggcccgaat tcgagcaggc cctcgccaac aagggctggg cagcactgcc     18060
     cggcctgcaa accaatccga actccttggc tgatttgaac ctgccggcct ggggatcact     18120
     ccggctggcc ttgccgatga acggcaacag cgacgccacg tttttggccg gcgaggcggt     18180
     agcgactgcg tcggtacctg ctggtgcacc tgcaatccag ggcgtgggag cagtgcgcac     18240
     cttaatgagc gcccaaccca aactcgccga cagcacctgg gcagaagcga tgagcacact     18300
     gctcaaaccc ggtgacgtag caactgcacc agtgcacgct gtgatcacca ccgagcagca     18360
     gctattccaa cgcggccagt cattgtcaga cgccaagagc gctttgggat cctggctacc     18420
     gcacgggcct gcgcctgttg ctgactatcc cgcggtgctg ctcaacggct cgtggctgac     18480
     acaggaacaa gccgcagcgg ccagtgagtt tgctcggttc gtgcaaaaac ccgaccagct     18540
     agcgaagctg gctaaagctg gttttcgagt taacggcgtc acaccgccga gcagttccgt     18600
     taccagtttc gcggcggtgc cttccaccgt ctcggtaggt gacgacggga tgcgcgccac     18660
     actggtcgaa gaaatgatcc agccgtctag cggagtagca gcgactatca tgctagacca     18720
     gtcgatgccc accgatgagg gcggcaaaac ccggttggcc aacgtcgtgg cggccctgga     18780
     cgacaagatc aatgcgatgc cgcccacctc agtcatgggc ctgtggacat tcgacggcca     18840
     caagggtcaa acagaagtga caaccggtca gctggccgac ccagtcaacg gccagccccg     18900
     ctcagcagcg ctgacggctg cgctggacaa gcaatactca tccaacggcg gtgcggtgtc     18960
     atttaccacg ctgcgaatga tctaccagga gatgctggcc aattaccacg ttggccaaac     19020
     gaattcggta ttggtgatca ctgctggacc gcacaccgac caaaccctgg acggagcgag     19080
     gctgcaggat ttcatacgca ccagtgccga cccggccaaa ccgatcgcgg taaacgtcat     19140
     cgacttcggg accgaccccg accaggcaac ctggaaagct gtcgcccaga tcagcggagg     19200
     aagctaccag aacttgtcga cgtcggcctc tcttgacctc gctaccgcga tcaacacatt     19260
     tttgagctga gctcgtcgac gcggtacgga gcgcaatgaa cgttgaatgc attccagatc     19320
     cccagctgta cctatttccg tcggactgtt tcgacagctc acgagggcgc atccattaca     19380
     tcgacgatgg agatgccccg gccaatgttg ttgtgccacg gcaatcccac ctggagcttc     19440
     atgtaccaca acattgtggt cgcactgcgt gatcggcttc gctgcatcgc gcccgatgat     19500
     ctcgatttcg ggttctctaa gcgtcccgcg ggattcagct gcaaaataca cgaacacctc     19560
     cccaagtggt gggcaagttg gtcgttgacc tgaaccaaga ccgcagacaa ctacctgacg     19620
     atgaacgagg actggggtgg aacggatcag catgacggtc gcggtcgagc gtgccgctcg     19680
     ggtgcgcggc atgaatttta ggaaatacct gattttagcc gacagacacg tggacaacaa     19740
     agaccgtcag caggagtagt gtacagcctg ccgatgcagc tacccgatcc tgcgataaaa     19800
     tttctttgtc gagaggctgt atccccacca gaacagagcg ccgactcagc accgcggtga     19860
     tagcacatta ctgggcggta taacccaacg ccacagcacg gttgagcata gccgaaaatg     19920
     cccaagcaga tcctgcctgg ccgcccgtcc tctgcgggca cggcacgtgt aagaagtgtc     19980
     agccaaactc ggtaccaaac cgcccttgtt tgtgtaggac atgaaggatt ttgccttcag     20040
     acttgaccct acgctgccgt gtatgcgcga gacgctcccg aataacatcc tggtcgaaca     20100
     tgcacactgc caagtaattt caagccggcg ataatcctcg agagcttagg ctggatggtt     20160
     cggggccggc tcagacgaac gcctccaccg gcaggcacga gcacaccaaa ttgcggtcgc     20220
     cgtagacacc gtcgatacga cgcaccggcg gccacacctt cggccggaac gctttgccaa     20280
     gcggataagc ggcctcttct cgggtatacg gatgatccca gtcggaggcc agcaggcact     20340
     cagcggtgtg cggtgcgccg cgtagtgggt tgtcctcaac agaccactcc cctgcaccga     20400
     cgcgggcgat ctcgccacgg atggcgatca tggcctcgca aaatgcatca atttcggcca     20460
     ggctctcact ctcggtgggt tccaccatca gcgttccggg caccgggaag ctcatcgtgg     20520
     gcgcgtgaaa accataatcc gccaagcgtt tagcaacatc gtcgacagtc acaccaaccg     20580
     acttggtgat cggtcgcaag tccaggatgc actcgtgggc gaccattccg ttctcgccgg     20640
     tgtacagcac cgggaagtat ttgtcgagcc gacgggctat gtagttggcc gaggcgattg     20700
     cggtcagcga tgccgttcgc agaccgtcgg cgcccatcat cctgatatag gcccacgtga     20760
     tcggcaggag tgaggcggac ccatacggcg ccgacgacac cggctgacct tgcggcagtt     20820
     cgggagcaaa ggggtgaccc ggcagaaacg agaccaaatg cgaacgaacc gccaccggcc     20880
     cgactcctgg tcctccgcca ccgtgcggga tgcaaaacgt tttgtgcagg ttcaggtggc     20940
     tgacgtcgcc accaaacttg cccggccggg ccaggccgac cagcgcgttg aggttggccc     21000
     catcgacata aacttgacca ccggcgtcat gcaccgccgc gcagatctcg gcaatgtcat     21060
     gctcatagac gccgtgtgtg gacggatagg tgatcattaa cacggacagc cggttggcat     21120
     gctcgctgag cttgatacgt agatcgtcaa gatcaacgtc accgttatcg tggcaaccca     21180
     ccacgaccac gcgcataccg accaacgccg ccgatgcggc gttggtgcca tgcgcgcttg     21240
     acggaatcaa acagacgttg cggtgcggtt cccctcggct gacgtggtag tcgtgaatcg     21300
     ccaacagacc agcgtactcc ccctgagagc ccgcgttggg ctgcaaggaa accgcatcgt     21360
     agccggtaat ctgcaccagc cagctctcca agtcgctaat gagacgacgc agcccggggg     21420
     tgtctgatac tggtgcgaat ggatgctggc gcgtgaattc ctgccaggta atcgactcca     21480
     tctcggcggc ggcgttgagc ttcatcgtgc acgaaccgag cggaatcatg ctgcggtcca     21540
     gagcgatatc cttatccgcc aaggcacgca agtaccgcat cattgaagtt tcggtgcggt     21600
     acttggtaaa tgtcggatgc gtcaggaacg ccgaggttcg ggtcgcgata tccggaccgg     21660
     cgaagctcgc ccgcgccggc gtcgctgcga acgccgccaa cacggccgtg atgtgctcat     21720
     cggtggtggc ctcgtcacag gccaccgaaa catggtcgcc gtccacgagc cagacattga     21780
     taccgcgctc cttcgcagcg ccctgaattt gcaccgtccg gccgggtacc cgggccagca     21840
     cggtgtcgaa gaacgcctgg tgtaccacct caacaccggc tgcggacaga ccggccgcca     21900
     gggcgcgtgc ctgtgcatgc acccgccgcg cgataccggt caatccctcg gcaccatggt     21960
     aactggcgta catcgcagcc atcaccgcca acagcacctg tgcggtgcag atgttgcttg     22020
     tcgccttgtc tcggcggata tgttgctcgc gggtctgcag cgccaaccgg taggccggtg     22080
     tgccgtcgct gtcgacagaa acacctacca accgacccgg cagctgacgg gcatgcttag     22140
     tgtgcagggc gaggtatcca gcatgcgggc caccaaatcc cattggcacg ccgaacctct     22200
     gagtagtacc gaatgcgacg tcggcgccga tctcgcccgg tggcgtaatc aacgtcagcg     22260
     ctaacagatc ggcaccgaca gcgaccaatg cgccgcggct gtgggcctgg gcgattaaag     22320
     cggtccagtc ggtaatccgg ccgctggctc cgggaagttg ggtgatgacg ccaaagaact     22380
     caccgtccgg tagtccttcg cgtaggtcgg ccacaacgat gtcgatgcct aacggtttgg     22440
     cccgagtggc gaacactgcg acagtctggg caaacacgtc gacgtcaacg accacccggc     22500
     tcgccgtact gcgggcagca cggtacatca atgtcatggc ctcggctgct gctgtgccct     22560
     cgtcgagcat cgatgcgttt gcgatctcca agccagtaag atcgctgacc agagtctgga     22620
     aattcagcaa cgcttccagc cgaccctgac tgatttcggg ctggtacggc gtatagggag     22680
     tataccaggc cgggttctcc aagatgttgc gcgacagcac cgctggcgtg agggtgtcgt     22740
     agtagccctg cccgatcatc gatacggcaa cggtattagc acgagcaagc gcacctagct     22800
     cggctagcgt ctcggactcg gtagccggcg gcggcaaccg gtccaggccc ggtgcaacgc     22860
     cggtgtcggt gacattatcg agaatgtcgc taggaactgc cttagctgcc agatcgtcta     22920
     gcgattcgac gccgatgact gcaagcatgg tcgcaacgtc ctcgctgtta gggccaatat     22980
     gccgggctgt aaagcaggtc tgcttgttcg atgagttcgg taccgacact cagaaactcc     23040
     tgatgtaaag ttagagcgca acgcgatgat gttgccaaca tcgcgttcgt aactgacggt     23100
     cacagaactc tcccgcgtga gggcgatgca gatccaactt taccctccgc ctcgcacgcg     23160
     agggtaaaca ataggaagcc gctaactacg ctgcagttag ccaattttac ggtcgcgatg     23220
     cttgcgccgg gaagccagtt cgtcttccgg cgcagctatc gactcgccac catcggcgcg     23280
     ctcaccacgg aagtcgtcga tcacgccggt cagctcacgc atagcgccgg acacggcaat     23340
     accgaacacg ccctgcccgc cttgtaacag gtcgacaacc tcttctgccg acgtgcactc     23400
     atacaccgta gtgccgtcgg agaacaaagt gatattggct agatcctgaa cgccacgctg     23460
     gcgtaaatgg tcaacggcaa cccgaatatt gtgcaacgag ataccggtgt cgagcaatcg     23520
     cttgacgatc ttgagaacca ggatgtcctt gaacgagtac aggcgctggc tgccggagcc     23580
     agccgcaccc cggatagatg gaaccactaa tgacgtccgt gcccaatagt ccagctggcg     23640
     gtacgtgatc ccggcgatct ggcaggcgct gggcccgcgg tagccaacca actcgtcagg     23700
     cacggagtcg tcagggaaga gtccgggttg tgctggtccg cttactgcgg tagggccatt     23760
     gaggccaatg tcaccatggg ttgtagcggt cggggtgtcc cggtagtccg caaggtccag     23820
     ctgaccttga cgtggctgct cgctcacggt gtttcctctc gccgatcgcg ctctggtcac     23880
     tagatgcgtc attggctccc ctcggtagcc atgtttggtc aggcccgagt gctaaaaagc     23940
     atacgctgtt cggtagttgc cctacctgaa gtggtcatca aaatatgacc gtcgctaaaa     24000
     tctgtcagca ctatccacta ggcgtgtcgc atcgcagtgc tatacgagac gcattcgtga     24060
     tgttagcgca agcgtccgta cccgccttca cgcccatcgt tacacggcgc gcatcgtcgc     24120
     tgggctaggt cgctttgaaa tcgtcaggcg acacgctgtc gagaaactcc ttgaacttct     24180
     ctacctcatc ctcgcgaaca gcgccgccga cctcctcatc attttcgtcg ggaatcagca     24240
     ggccggcttg agcaagcacg acgtcctcga cgtagatcgg aacaccgacc cgcaaagcga     24300
     tcgccaccga gtccgaagga cgcgccgaga ccttgatatt gcgatcgaag atcagatcag     24360
     cgtaaaaagt gccttcctgt agatcgacga tccgcacctc tttaagtgaa tgcccaagcg     24420
     cggcaatgac gtctctgatc agatcgtgcg tcagtggacg gggcggttcg ataccttgct     24480
     gctccagcgc aatcgcggcg gcctccgact ggccgatcca gattggcaga taacggtcac     24540
     cattggcttc tcgcagcaac agcaccggct ggttctgcgg ctgctcgaca cgaatgccga     24600
     caacacgaac ttcacccatc tttgtccgcc ctccgcactt gccgctgtgt tcgattcagg     24660
     ctcggcacga cgacacggta gacaccgtgc cttgccacgc cgccgaacac caagctgtcg     24720
     aacgaagtct aatcctcagc ggtgtagaac gccgcgaacc gcagatttga tcaacgaagt     24780
     gtgcaaagtg atggcgagcg cagcaacctc acgcgccaag tcgtcggcgc ggtcacgggc     24840
     accggcctta ccggctttga cgatcggccc ggcgatttgg acgatcaggt cggactggcg     24900
     gtcagccgct gaccggaagg ctcgcagatg ccgcggctca acaccgtact cggacagcgc     24960
     ccgcgcgcat tggaggatca cgattgcatg ctcatcgaaa aatccgcccg gcccggtggt     25020
     aatcacaccg gccttgagca gcgccgtcaa caagtcgtct gccactcctg agcggtccaa     25080
     gaggtcttct cgactcagcc ggacgccggc gggcgatacc gccgggatgt cggatccgac     25140
     ccccgatccg acaccggcac ccgggccgcc cgtcaccgaa aacaatcggg gtgcgacata     25200
     aggcgacccg aatgatggta actcaccatc aggctgggcg tccagctgcg ccctaataac     25260
     cttcagcggt agatagtgat cgcgctgtgc agttaggatg aaccgcagcc gtgcacaatc     25320
     atacgcggtg aaccgccggt accccgatgc agaacgctga ggggtcacga gcccctcagc     25380
     ctccaggaaa cgaatcttgg agattgtcac atcaggaaaa tccgacctca gcagatccaa     25440
     gaccgcccca atcgacatcc cgaccagtgc cgggctatcg ggcgcactca cttgcctgcg     25500
     gttcgcccgg tgtcgtcatc ctgcttggaa ccgatcagga acactaagcg gaatttgccg     25560
     atctgcactt cgtcaccgtt tgccaatacc gcagaatcca ccggctcacg gttgacgtag     25620
     gtgccgttga ggctgccaac atcgacgaca tggaactcat taccttctaa ccggaattcg     25680
     gcgtgacggc ggctcaccgt gacgtcatcg aggaagatgt cgctgtcagg gtgtcggccg     25740
     gcggaggtga tggcctggtc gagtaaaaag cgcgatccgg cgtttggccc ccgtttgacg     25800
     accagcaacg ccgagcccgc cagaagtcct tcaaccccgg ataccacgct ctcagcacct     25860
     gcctgtgctg gagcgtccag ttcgttgagg aagtcggcgc ggaagaccga agtcgtctcc     25920
     acggtgactt cgtcagaagt ctggtcttct tgtcttcctg agtccatgtc cgtcacccgc     25980
     tgctccttac tggccgctgt ggcgttgcct gacccgggcc actcggcccg gcttcccgct     26040
     aggttctcca cctggtactg ccgattacag ccatctaggg ctcatgtgtc gaccgtaccg     26100
     cgcggcggtc tgcaatgcgc caaccaccac aggatcggac cctcattgcc cagctcctcc     26160
     tcgagcagcc cggcgtccgc atcatcgtca cgtgggattg ccaagcaccc tagcaatcat     26220
     catttggtta gcgtgccgcg ataagtctcg gcgtcaagca gcgttgcgat agctgactcc     26280
     aaagccccga cgtcggagac gtgaacatcc agtagccagc cagcgccgta tgggtcagag     26340
     ttcactagtt ggggactgcc ttccagatcg gtgtttaccg ccgacactgt acccgacacc     26400
     ggtgcataca agtccgacac cgatttcgtc gattccactt cgccgaagga tttgcccgcc     26460
     gctaactcag cgccaacttc tggcagctgg acgaaaacca catcacccag tgtcgactgc     26520
     gcgaagtcgg tgagcccgac ccggacggtg tcttcgcgac tgcgccgaat ccactcatgc     26580
     tcagcagtgt aatgcagatc ggacgggata tcactcacgg taatcctatt ctggtcggtg     26640
     atctacttga cgggctgagc gtattggtgc gattttggtg gccgcaaggc ggttacgtcc     26700
     actcgatcga cttgttgcac cgacaccacg cggccaacgc atttgacgct gtcctgacca     26760
     cccaggtatc gataccgacc cgtaccgact ggtatgcatc attgatctcg atcgcctcgg     26820
     cgccggcggc acacaacttg ttgatcacgt caagcattgc ttggggcacg accccggggc     26880
     cggtatcgtc gatcgtcaac gtgacacccg gcccagtgac gccgacggca ccgaccagta     26940
     tgaacagcac agccaatcga gtctgggcgc tttggatggg atggcggcct gatcggtgtt     27000
     gcctgatgct tgcgacacgt tcaacatgtt ctgtagttcg gtcacttagg tgttaacgtg     27060
     acctcgcgtt gccgtaacgg acctagcagc accaacaggt cggcagaacg cgcagttttt     27120
     aaggaatcat cggacttggt ctggcagacc tgggtgacaa tggcgatccc caagagcaag     27180
     cacaacagga tcactagcgt tccaaacgcc agacgcgagc gaccgctccg cagtgacccg     27240
     gacagtcccg tgcggcatag cgacccgcta agttgtcgcg gatagtcggc ggtagttcgt     27300
     tgcgcccatg gcgcgccgct tcacgagctt tggggtcggt gttgggttga gtcatgccga     27360
     tttggctcgt cacaaccttc ccattctggg ggaccagcgt gtaccagggg atcctggtac     27420
     acgctgacct catatcggtc atggcaccgc ttctcttccc acatatcact ctttcgctct     27480
     gcatcgtcac cagtgcatgt cacgccccga acagcctgcg ccgcagcgtg gcggcactgc     27540
     caaagatacg aatacccagc accacaatga tcgccgtgga tagttgcgta ccaacgccca     27600
     gctggtagcc gacatagacg atcagggcag ccatcgagac gttgaatacg aacgaaataa     27660
     cgaacacctt cgggtcaaag atccgctcaa gataggcaca cagtccgccg aacaccgcgt     27720
     cgagcgcagc gaccacagcg atcggcaaat actggttaga tgagctcagg ttcgctagag     27780
     tgaaaagcta ggcccaggac gatgccaatc gcaagcacta cgagaccgta gcataatggt     27840
     cggattccct acgagttgcc ccaaggggaa tcattatcac gcggactttg tctcagactt     27900
     tgtctcacta ggacccaatt gtttggccaa tttgatacct cggatcgctc cagcgggcaa     27960
     cgtgagaccg taggcgatgt tttctacgct gacaccgacg ccgtaggagg cttccagcag     28020
     cctgaggcgc tggacaacag gggctgtcgt cgaacacgtc cagcatggat tgcggtgacc     28080
     ccaccggcga ggatgtgtag ggattgttgt caaccaggat cgctccaccg gcctgccgaa     28140
     tagtcacatt aggcccaatc cgtgcgccat caactgagat tgtctcagca ccgctcgctc     28200
     acaacgggtt aacgataagt tgcaggtcgc ggtctagaat gatttaccga ctgcccttta     28260
     tatgcgttgc ttggaatatg cgttgcttgg acacatcgga aagatattag agcctaaact     28320
     ggggttggtt acactcaccg tcaaaccagg cccgatgatt tagtgtgctg gcggccgcta     28380
     tgctaagcac atcgaggcgg tcggcagtcg tcgaccctcg gcgttgtgtg cgagcccgag     28440
     ctgctgcaca tcgtcgactt gagccgaaag cacactgcgc tgttgatcta gcttggccgc     28500
     aacaggcctg ggtagaacac acttgccacc agtaactgct gggcggcgcg cacaccaggt     28560
     gtgaccaaac aagcttgtgc agccacgaca gcaaataccg tggtgaccag agccagctac     28620
     caacccttgc tagatccaac tgaaagcgca ggcgcgcggc atggttgagc agccacgctc     28680
     agcagctgcc gcggacgtaa ccgggatcga aacgtacggg acaacgaagc acacggcagc     28740
     gagggcacac cgggaccttc ttgggcgggc ttccgcgtga agattctagc ccgctttcgg     28800
     gtcatagccg ctgagctgtc gctcacgttc ggccatattc atctggcctt tcccgcaaac     28860
     tgacgatggg cttggtgctt gatcttaggc atccaccgca ccaccatcgt catctgcacc     28920
     acatacagca cgaatgccca caggtacgca taggtacccc agatcagaaa cgcccaaccg     28980
     caggccccca gaacacggct ccacaacgtg tcccaagttc ctagaagaac gaatggaaag     29040
     ccgaccatca agctgaacgt cgccgcctta ccgatatagg tcaccggtaa tgacagcagt     29100
     ccgcgactcc acagcaacgg cagcgttgcg gtcagtagca cgtcacgtgc cagtagagcg     29160
     acgacaaacc accacggcac gatcccgctc aacgccaaca cgacggggat cgtcaccatg     29220
     tacagccgat cgacagcggg gtcaagcagc acacccaacc gcgaatactg atccagcagc     29280
     cgggcaatct tgccgtcggc ccagtccgag acaccgctga acaccagaat caccaccgcc     29340
     cagccatcgg cgtgcatgac cagcagaacg tagacaaacg ccgggatcag cgccaggcgg     29400
     acagcgctga gcaaattggg cactgtcagc acccgattgg gcggacacac cgactccatg     29460
     agcagtgacc ttagcctggc gatatgacgg tccggataac gggccgaaag caatcggacc     29520
     tcagcggaaa accccgggta ggctcaaggg agaaagcgtg tcatcggaca gcggggcatc     29580
     attgaccatg taggtccacg tcgacgtcgg ccgcgctagt ttggacaaat ccagtcctgg     29640
     cgccccatca aggatattcg cggtttcgaa cgtctgctgg gccgcctcga tcgcgtcggc     29700
     ggccagcaaa gcaaacgcgt tcaccgccaa ccggtgaaac tcgtccagag gactttgccg     29760
     gccgagcgcg cgcaaatgga tactttcacg aatgtcagcc agatacgcca gatgatcggc     29820
     ccagccacgg tcgaggtgat acaacatgat caatcggcag atcgtctcga gccgttcttc     29880
     ggcctcctct ttgggcagtg cctgagccag ctcctcgtaa cgcttgggcg ccagctctgc     29940
     gagctcctcg cgcgcggttg cactactcag caacgcgttt cgccgatcca cgatgatggc     30000
     gcgctgctgg gctatcaact ggttgtagcg ccaggtattc gcatgcacgt ccagcagccg     30060
     accctccgca acacgctggg catggtcaag caaaccggtg gttttgaggc tgatgatgcg     30120
     gccatcctcg tcggtctgca tcggcaactt gttgcggtcg aggttggccg caatgacatc     30180
     atcttcccag ctggagaaga acaccgacga tccaggatcg ccctggcgcc cagcccggcc     30240
     acgcaactgg ttatccaatc gctcggtatg gtgccgcccg gtgccgacca cgtgcagccc     30300
     acctagctcg acgaccctgt cgtggtcgga ttcgtcagat ccaccaagac ggatatcggt     30360
     gccgcgccca gccatctggg tggacacggt gaccgcaccg aatttgccgg cttccgcgat     30420
     gaaccgcgct tcttcggcat cgtttttagc gttgagcacg accgcgggca cgccgtgtcg     30480
     cagcaaccgc tcgtgcagct cctcggattc ggcaacgtta cgggtcccga ccagcaccgg     30540
     ttgacccgtt tcgtgcacct cagcgaggtg cgccacgatc gcgtcattct tggcggccgc     30600
     ggtgatgtag actcggtccg acgcgtcgtc acgaatgttg ggagtattcg gcggtatcgg     30660
     tgacacaccg agcttgtaga actggcgtaa ctgctcacca gcggccagcg ctgtgccggt     30720
     cataccgcac acagtggcgt aacgattgat cagtgcctgc actgtgatgg tatcgagcac     30780
     ttcgccggtc tcggtggtct cgatgccctc cttcgcctcg accgcggcct gcaggccgtc     30840
     cggccagcgt tgcagctgtg cgatgcggcc gcgggaggcg ttgactagat gtaccgcgtc     30900
     gtctcggaca atgtagtgca cgtcacgctg caacagcaca tgggcgtgca atgcgacgtt     30960
     tacctcggtc aacgtggtgc caacgtgttc ctcggagtac agatcgatgc caccgagcgc     31020
     cttttcgacc ttgcgcgccc cgacatcagt caggtggacg ttgcggctgt cggaatcggt     31080
     gtcataatcg gattcggcgg acagctcgcc gaccagcttg atgatctcga gccgcggcgt     31140
     ctcccgatgc gtggcaccgg ctaacacgag cggcaccaat gcctcatcga ccagcacgga     31200
     gtcggcctcg tcgataaggg ccacatcagg atggggcgat accaggtcgt cgacgtcggt     31260
     caccaactga tcgcgcagca catcaaaacc gatctcgttg accgaggcgt aggtgacgtc     31320
     gcagccgtaa gcagccttac ggtcctcgcg tgttgactcc gcggtgatcc agcccaccgt     31380
     caggcctatg gcctcgagca gcgggcccat ccattccgca tcacggcggg ccaaataatc     31440
     gttgatcgtc acgacgtgca catgccggcc ggcaagggcg tatccggccg ccgcaatcgc     31500
     gccggcgaga gttttgccct caccggtggc catctcgatc acgtcaccag caagcatgcg     31560
     tagcgccccg agtaactgca catcaaaagg cctcaaaccc gtggaccgct cagacgcttc     31620
     ccggacgatg gcaaggaatt gggggacgtc gcgagaatcg gcgagatcgt tgagattgag     31680
     caacccgcac gccttgcgca actgctcatc gcccagatcg gcagcttcct tgtggtaagc     31740
     cgccgcagca gtgacctcag cggaagagta gtttaggttc ttgtccgtgc tggcgccgag     31800
     tagccgccaa aatcgactac tcagacggcc aggctgagtg cgaggcgtct tagacacagg     31860
     ttaacggtac gctagccacc gatcacctca agcaagcgcg cctgtacacc gacacgccgc     31920
     taaccccggc aatctgcgga cattcgcggc ccgggccggc gtgatcaagc caggttggac     31980
     cggcgagggt aggcgacact cggatcggtc agcacattca cgaccgacgg cagaccggtg     32040
     acgaaagcac gttcgagtgc aggccgaagc tcaccgggca ccgacaccag ctcgccgtga     32100
     ccgccgaggg cacgaaccac ctcgtcgtag cgagtacccg ggcggagttc cgctaccacc     32160
     gagtagccgt acaacgcttc catcgggtgt ttctctaagc cccagatccc gttgttgccg     32220
     atcaccgaca cgacgggaac attgtgccga accagagtgt cccattccat gccgctgaag     32280
     ccaaacgcgc cgtcgccctg cagcaggaca acttgacggt tgggccgggc gagtttagcg     32340
     gccagagcgt agccagggcc cgaacccagg caaccgaacg gcccgctgtc caaccagcaa     32400
     cccggtagat agctgtcgat cacccggccg gcataagacc cgaaatcacc ggcgtcgatc     32460
     acgacaatcg cgtcgcggtc cagcagcgac gcgagctcag cgtacacccg catcgggtgc     32520
     agcgggagcc ggtcgtcgtc cagttcagct ttctcaaggt cacgcgtggc ggtctcggcc     32580
     gtccgcagcg cgcggatcca gtcctgactg tcggtcccac cgactccagc caacgccgag     32640
     agaatagctg gcaaatctcc gtagagcccg gccgcgacgg gtcgcggata gtcgcgatcg     32700
     ggttcagcac ggtccgccac cacgagctgt gtttgtgacc cgaacacctt gccgaagccc     32760
     agccggaaat ccatcggcac cccaacaacc agtgccacat ctgcctcacc caatgctttt     32820
     ccccgcgccc gcgagaaagc caacgggtgg tcggcgggca ctacgccgcg tgccattccg     32880
     ttcatcagca cagggatctg gcattcctcg gctagacgta gtagcgcggc ctcggcgtgc     32940
     ccccaccaga cgttggtccc ggccatgatc accggccggt gcgccgcggc taacaggccg     33000
     gcagcccggt ccagggcttc ggggttggca gcgggagcca caggcaagtt ggccaaagcg     33060
     ccaggaccac cgccaacgtc gtcagccatg gaaaacacat agtccatcgg gaaatcaacg     33120
     aaacccactc cggacggggc aaccaccgcg gcctgcaatg cttcgtcgac aagccggccg     33180
     gcggcatccg ccgactgtgc ggtggcggcg aaacgggcta gcggagccac gaacggcacg     33240
     tgatcaatct cctgtaacga gcccataccc catcgcagtg cgggtgctcg gccgccgagc     33300
     actaccagcg gcgactggtt ctgctgcgcc gccgccatcg cgctcatacc gttggtgacg     33360
     cccggccccg cggttagtac agccacacct ggctgcctgg tcactttcga ccaaccctcg     33420
     gcggcgaagg ccgctgtctg ctcgtggcgc gtgtctatga gcctgatact ctcgctacgg     33480
     caaccgtcgt aaatggaaaa tagatgccca cctgacaacg taaagacggt gtcgacaccg     33540
     ctggctttga gtcgacgtac gacgagccgg ccggcgtgaa tgctgtgggt caggacaggg     33600
     tcggtgctca tatcagcagc ctatccgcga ctttcgggta ccttcgccga gagatttctg     33660
     tattgaggtg ctttcagcgc ctcaatcgcg aggagacatc aaacgtggag ttaagaccat     33720
     tctatccatc tgtcaactgg ggctacgcgc tgccagactc gttgtggtgg atcgccaagg     33780
     catgggcgat cagtgccgct tgcgtcgttg tcttggtaat gctcagtttt atcacccgct     33840
     ggggtcgcca atactggcgg attacccgcg gctatttcat cggaccgcag tcggtcgggg     33900
     tgtggctgat gctagctgtg ctgctgttct cggtcgtcat cagcgtgcgg ttgaacgttt     33960
     tgttcagcta ccaaagcaaa gacttgtata acgcgctgca agcagccttc gaaggcgccg     34020
     gcgcacagaa cgacctggtt aaacagtcag gtatgcacgg cttttggatg tcgctcggaa     34080
     tcttctccat tttggcagtc atattcattg cccgcgtgat ggccgacatt tatctgaccc     34140
     agcggttcat catcgcctgg cgaatgtggc ttaccaacca cctcacaact gactggctgg     34200
     accagcgcgc ctattaccgg gaacaattca tcgacaatac gatcgacaac cccgaccaac     34260
     gtatccagca agacatcgat atcttcaccg ccggcgccgg cggcaccccc aacggtccct     34320
     ccaacggaac gggcagcaca ctgttgtttg gggctgtcga atcggtgata tcggtgattt     34380
     cgttcaccgc gatcttgtgg aacctttccg gtcggctcgc cgtgtttgag ttcgaaatac     34440
     cgcgcgccat gttctggatc gtcattgtct acgtgctgtt agcaacgatc ataacgttct     34500
     ggatcggccg cccattaatc gggctgaact ttgccaacga aaaactcaac gccgccttcc     34560
     gctatgcgtt agtgcggttg cgcgacgctg ccgaggcggt tgcattttat cggggtgagg     34620
     aggctgaacg gaagcaattg gagcagcgct tcacaccgat tattgacaat taccgcaggt     34680
     acgtcagccg cactataaga ttcctaggtt ggaacgcctc ggtaagccag accattgttc     34740
     cgctaccgtg gattcttcag gcaccgcggc tgttcgccgg gaaaattaac ttgggggacg     34800
     tcggccaaac cgcgaccgca ttcggcaata ttcacgactc gttatcgttc tttcgcaaca     34860
     attatgccgc atttgcggct ttccgggccg caatcatccg gttgcatgga ctcgtcgttg     34920
     caaatgctcg cagccgggag ttgccccacg taacagctaa gtcgacgaac gatggtacag     34980
     ttcatgtggt cgctgtcgag gtgcgaacgt cggcaggcga gcagctgatt gacccgctcg     35040
     acctgcaact taattgcggt agttcactgg tcatcactgg gcgctccggg gtaggcaaga     35100
     ccacaatgct gcgcagcctg gccgaattgt ggccatacgc ttccgggacc ctaagccgcc     35160
     ccgacggcaa gaacgaaacg atgttcttat cgcagttgcc ctatgtacca ctgggcaacc     35220
     tacgcggcgt ggtgtgttac ccaaatgcgc ccgccgacat ccctgaagac actgtgcggg     35280
     acaccctaac gaaggtagcc ctcaacccgc tgtgtgaccg gctagacgaa gaacgggact     35340
     gggccaagat actatcccca ggcgagcaac aacgcattgc ctttgcccgt atcctgctca     35400
     ccaaaccaaa ggcaatattc ctcgacgaaa gtacgtccgc gcttgacgaa gggctggaat     35460
     tcgcactcta ccaaatgctg cgaagcgaac tgccagactg catcatcgtc agcgttagcc     35520
     atcggcgcgc agtcgagctg ctccacgcac aacagctgga actgcttggc ggcggccagt     35580
     ggcgactggg cccagtggaa aaggagccgc tgcatgtcta gctagcgcgg tgctaccgca     35640
     cgctaacagg tagcaccctt gcagggttaa cgagtacagg ttcgcatgcc cgagctcaaa     35700
     ttcacgggac gaagtgtcca tgtagagcac atacggaccg tgcttttctc gccggccaga     35760
     ggaaatcgcg gtccgccggt gattcgtggg tgtgcaaaca tgcaagccac gcccgacagg     35820
     ttcgggcata gtcagtcgcg tcgatctttc gttactttct tcacctcaaa ccatttctcg     35880
     cacgcggtag gcaattcagg cgctctagtg gtgggtggtt ttgaggcgtt taggtgtggt     35940
     tggttgaggt aagtgggcgg tgtatgtggt tgctgtcttg gagttgcgcg atggcgaccg     36000
     gggtcggctg gggtggttga cgagggtgtt gtgggtgctg gtggggcagg tgacacgggc     36060
     gtggattgtg tggttggtgt ccgatggagt ggctagatac tgatatcgcg gttcgggtac     36120
     gccggggacg ggacgtgctt cggtgatcga tgaggtcatg gtgctcgtag agacgttggt     36180
     cggcgatgtt atgcgaatcg gccgttcagc gtcggagcgg cccgtcaccg gagcagttga     36240
     tggctgtggg ggatttcgtt ttccttggtc gcgcggatct ggcataagtg ggggcatcca     36300
     gtcgcatcgc gtgaagacct tcaagttcgt taccgacccc gacgtgggag accaaacggc     36360
     gtgatgtggt cgggctcgac ctggatccac gtgcgtcacg aagtgctgat gattggcatg     36420
     gcagtgaagg tgagagatct tcgccgccgg gcctgtcgca gcaggaacgg tgaagcgggg     36480
     gcaccttggc cttgggtggc gtcgggaagg ggaggaatcg tcctaggtcc tgcttgggtg     36540
     ttgtgtggcc aacacgattt atcgggttgg ggtcatcgtc ggtcgatcgt ggccgcaggt     36600
     ttgatgacct gttcaatctc gtgtgtgacc cggcgaacat tgttggtggc gtttgactgg     36660
     gtcacgggca actatggggc gaatactgct ggtgtggacg cccggaccgg agcccatgtt     36720
     gaggaaatcg tcgaggtagc gggttgttgg acaatctgcg gatcgagtcg ttcaggctgc     36780
     gttgaagctg gtgttggagc ctgtcgtcga ggccgctttc gagccgatct cccctggatt     36840
     ccgcccccaa gcggcgatct cagggacacg atcgccgaaa ttcaccaata cagcactaca     36900
     agctatcggt gggtgctgta tgcagacatt gaggtgcgct gtgactctat ctcacattct     36960
     gctctgttgg agcggatgct attgccagtc aaggataaac gcgtacttgg tcctggtgaa     37020
     ggcgttttct aaggccggtg tgctcaccga gtctggtgag caccagaaca ctcacaccgg     37080
     aacgtctcag ggcaatatct tgtcgccggt gctgaccaac atcgccttgc ctgggctcga     37140
     tgagtatcgg atgcagccat ggaaaccgtg cggctcgatg tccactgctt acctgcctag     37200
     tcggcgccgc gtcacaggcc tgctgagtac aacgcagtcg tcccgcgtag cggacgactg     37260
     cgttgtactc agcacatggc gaccagacac gccagaggcc tgcaaaacga aataaactcg     37320
     atgcttacgc ctctaggtct gcagctgtcg actgcaaaga caaagaccgc gcacttcggt     37380
     aactggtatg gactttcgcg gcttccacac cgggtggaca cccaagaagg caacgaccac     37440
     gtgggcatgt ctaggacttg tatcgccgac cgggcacgac ggtcggtcaa agccaagatc     37500
     cgtgccctgg caaacaggaa atcacagcgc aatccggggg ccgtgctggc acagatcaac     37560
     catcggtggt ttcgagcact gtatcgccgg agatggaaag acattcgccg gcagttcacc     37620
     acctccgaaa aacggtgaaa accgattgac gcagaagaga ccaccctatt gaacccgacc     37680
     tcgataccgg tcacccggta ccgctaccaa atcaccacaa tacccaaccc ttggaccagt     37740
     attcccaccg cctaacggta gtgaccatga aaagcccggt gcgcaaagac gcgcacacca     37800
     ggatcggcga ccagtctggg aaacggaccg aaagtaatac acccacaccg cgccccaggc     37860
     ctactcaacc cgcggccgcg attatgctct agcgtcgaca atgaagcccc agacccaagc     37920
     agctggatca cacccaaacc gattctgcca ctaccttcaa actcgccacc aaaacacacc     37980
     cacacataca ggcatgcccc aatctgcgac aactacgcca acccacaaac ccccagcagc     38040
     cgatcctggc tacaggataa ccagcaagcc acactgcact tcacaccgac aagctgctca     38100
     tagctgacac ataaccaaaa tcttcttcac caccatcacc cgccacaaca cgttcaccga     38160
     tatcaacaac ctcgaaaccg cgatccccac ctacaacgaa cacaccacac cgttcacctg     38220
     aacccagacc gcagacaccc cctcaacaaa atcaaacgtt aaaacaatca ccaacacaca     38280
     acactagcga acacatcaga cctgtacggg cagtgccgac attccgcgca ttgccacatt     38340
     tggcttatag accaattcac cggccagctg tacctgtggg aaacgcgcac tgatcgcaga     38400
     taatgtgaca gtcgcttcca accgagccaa tgccgctcct aggcaaaaat gtgagccgac     38460
     ggcaaatgcc aaatgtcgtg agctgggacg gtcggggtca aattcatcgg ggcgtgagta     38520
     aaccgctgga tcgcgattgg cggcggcaag caacaaaacc attgtatcac cctcggttaa     38580
     agttgtctga ccgatcgtca tgtccttagc agctacccga ccgattagat ggattgctgg     38640
     atcataacga agcgtctcct caaccaccag cggcgcgcgc tgcgggttgc tacttagcgc     38700
     tttccactgc gacgggttgc gtaacatcgc caggaccgca ttggcaatca gattcaccgt     38760
     ggtctcatga ccagcaacga gcaacagacc gcacgttgcg atgatctctt cctcggtcag     38820
     ctgatcaccc gactcgtcca actcaatcag cctggatatc agatcctcac cgggtgtacc     38880
     gcgtcgacat ttaactagct gctccaagta atcccgcaac cacacaccag cccgcagccg     38940
     ctcttcagtg gcctccggcg gttcaccggt aatggtaatg aacgggtcga ctgactgcac     39000
     caatagtgct gagacgcgac cgaactccgg cgcgtcttcg tacggcacac ccagcagccg     39060
     acaaatcaca gccaccgcaa gcggaaaggc taggtcagca atgacgtcaa actggccagc     39120
     cgcggcaccc ttatccagca gggaatccac cagcgcagca atatcacctt ccagcgcctg     39180
     aacgactttc ggtgcgaacg ccttgctgac aagcttgcgt aaccgggt                  39228
//