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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   AJ891038; SV 1; linear; mRNA; STD; MAM; 1638 BP.
XX
AC   AJ891038;
XX
DT   21-SEP-2005 (Rel. 85, Created)
DT   11-JUL-2006 (Rel. 88, Last updated, Version 2)
XX
DE   Hylobates lar mRNA for succinic semialdehyde dehydrogenase precursor
DE   (ALDH5A1 gene)
XX
KW   ALDH5A1 gene; succinic semialdehyde dehydrogenase.
XX
OS   Hylobates lar (common gibbon)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC   Hylobates.
XX
RN   [1]
RP   1-1638
RA   Malaspina P.;
RT   ;
RL   Submitted (18-MAR-2005) to the EMBL/GenBank/DDBJ databases.
RL   Malaspina P., Biology, Universita Tor Vergata, Via della Ricerca
RL   Scientifica, Rome, 00133, ITALY.
XX
RN   [2]
RA   Blasi P., Palmerio F., Aiello A., Rocchi M., Malaspina P., Novelletto A.;
RT   "Human succinic semialdehyde dehydrogenase variation in higher
RT   primates:intra and inter specific data";
RL   Unpublished.
XX
RN   [3]
RX   DOI; 10.1007/s00239-005-0154-8
RX   PUBMED; 16786440.
RA   Blasi P., Palmerio F., Aiello A., Rocchi M., Malaspina P., Novelletto A.;
RT   "SSADH variation in primates: intra- and interspecific data on a gene with
RT   a potential role in human cognitive functions";
RL   J. Mol. Evol. 63(1):54-68(2006).
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1638
FT                   /organism="Hylobates lar"
FT                   /mol_type="mRNA"
FT                   /sex="male"
FT                   /cell_line="lymphoblastoid"
FT                   /db_xref="taxon:9580"
FT   CDS             1..1608
FT                   /gene="ALDH5A1"
FT                   /product="succinic semialdehyde dehydrogenase"
FT                   /function="GABA metabolism"
FT                   /EC_number="1.2.1.24"
FT                   /db_xref="GOA:Q3MSM3"
FT                   /db_xref="InterPro:IPR010102"
FT                   /db_xref="InterPro:IPR015590"
FT                   /db_xref="InterPro:IPR016160"
FT                   /db_xref="InterPro:IPR016161"
FT                   /db_xref="InterPro:IPR016162"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q3MSM3"
FT                   /protein_id="CAI69938.1"
FT                   /translation="MATCFWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLR
FT                   CYAGGLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRA
FT                   AYEAFCSWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFF
FT                   LEWFSEEARRVYGDIIYTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAG
FT                   CTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKIS
FT                   FTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGALASKFRNTGQTC
FT                   VCSNRFLVQRGIHDAFVKAFAEAMKKNLHVGNGFEEGTTQGPLINEKAVEKVEKQVNDA
FT                   VSKGATIVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAI
FT                   ANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGS
FT                   KYGIDEYLELKYVCYGGL"
FT   sig_peptide     1..141
FT                   /gene="ALDH5A1"
FT   mat_peptide     142..1605
FT                   /gene="ALDH5A1"
FT                   /product="succinic semialdehyde dehydrogenase"
FT                   /EC_number="1.2.1.24"
FT   3'UTR           1609..1638
FT                   /gene="ALDH5A1"
XX
SQ   Sequence 1638 BP; 362 A; 426 C; 489 G; 361 T; 0 other;
     atggcgacct gcttttggct gcggagctgc ggagcccggc gcctcgggtc gacgtttcca        60
     ggctgccgcc tccgcccccg cgccggaggc ctggtccctg cctccgggcc tgcgcccggc       120
     ccggcccagc tccgctgcta cgctgggggc ctggcgggcc tctctgcggc gttgctgcgc       180
     accgacagct tcgtgggcgg ccgctggctc ccggctgccg ccaccttccc ggtgcaagac       240
     ccggccagcg gcgccgctct gggcatggta gccgactgcg gggtgcgaga ggcccgcgcc       300
     gccgtgcgcg ctgcctacga ggctttctgc agctggaggg aggtctcggc caaggagagg       360
     agttcattac ttcggaagtg gtacaattta atgatacaaa ataaggatga ccttgccaga       420
     ataatcacag ctgaaagtgg aaagccactg aaggaggcac atggagaaat tctctattcc       480
     gcctttttcc tagagtggtt ctctgaggaa gcccgccgtg tttacggaga cattatctac       540
     accccggcaa aggacaggcg ggccctggtc ctcaagcagc ccataggcgt ggctgcagtc       600
     atcaccccgt ggaatttccc cagtgccatg atcacccgga aggtgggggc cgccctggca       660
     gccggctgta ccgtggtggt gaagcctgcc gaagacacgc ccttctctgc cctagccctg       720
     gctgagcttg caagccaggc tgggattcct tcaggcgtat acaatgttat tccctgttct       780
     cgaaagaatg ccaaggaagt aggggaggca atttgtactg atcctctggt gtccaaaatt       840
     tcctttactg gttcaacaac tacaggaaag atcctgttgc accacgcagc aaactctgtg       900
     aaaagggtct ccatggagct gggcggcctt gctccattta tagtatttga cagtgccaac       960
     gtggaccagg ctgtagcagg ggccctggca tctaaattta ggaacactgg acagacttgt      1020
     gtttgctcaa accgattctt ggtgcaaagg ggcatccacg atgcctttgt gaaagcattc      1080
     gccgaggcca tgaagaagaa cctgcacgta ggtaatggat ttgaggaagg aactactcag      1140
     ggcccattaa ttaatgaaaa agcggtagaa aaagtggaga aacaggtgaa tgatgccgtt      1200
     tctaaaggtg ccaccattgt gacaggcgga aaacgacacc aacttggaaa aaatttcttt      1260
     gagcctaccc tgctgtgcaa tgtcacccag gacatgctgt gcactcatga agagactttt      1320
     gggcctctgg caccagttat caagttcgat acggaggagg aggctatagc aatcgctaac      1380
     gcagctgacg ttgggttagc aggttatttt tactctcaag acccagccca gatctggaga      1440
     gtggcagagc agctggaagt gggcatggtt ggcgtcaacg aaggattgat ttcctctgtg      1500
     gagtgccctt ttggtggagt gaaacagtcc ggccttgggc gagaggggtc caagtatggc      1560
     attgatgagt atctggaact caagtatgtg tgttacgggg gcttgtagga ttccttggtt      1620
     ctttaaaaaa aattgaaa                                                    1638
//
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