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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   AJ891037; SV 1; linear; mRNA; STD; MAM; 1638 BP.
XX
AC   AJ891037;
XX
DT   21-SEP-2005 (Rel. 85, Created)
DT   11-JUL-2006 (Rel. 88, Last updated, Version 2)
XX
DE   Pan paniscus mRNA for succinic semialdehyde dehydrogenase precursor
DE   (ALDH5A1 gene)
XX
KW   ALDH5A1 gene; succinic semialdehyde dehydrogenase.
XX
OS   Pan paniscus (pygmy chimpanzee)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
XX
RN   [1]
RP   1-1638
RA   Malaspina P.;
RT   ;
RL   Submitted (18-MAR-2005) to the EMBL/GenBank/DDBJ databases.
RL   Malaspina P., Biology, Universita Tor Vergata, Via della Ricerca
RL   Scientifica, Rome, 00133, ITALY.
XX
RN   [2]
RA   Blasi P., Palmerio F., Aiello A., Rocchi M., Malaspina P., Novelletto A.;
RT   "Human succinic semialdehyde dehydrogenase variation in higher
RT   primates:intra and inter specific data";
RL   Unpublished.
XX
RN   [3]
RX   DOI; 10.1007/s00239-005-0154-8
RX   PUBMED; 16786440.
RA   Blasi P., Palmerio F., Aiello A., Rocchi M., Malaspina P., Novelletto A.;
RT   "SSADH variation in primates: intra- and interspecific data on a gene with
RT   a potential role in human cognitive functions";
RL   J. Mol. Evol. 63(1):54-68(2006).
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1638
FT                   /organism="Pan paniscus"
FT                   /mol_type="mRNA"
FT                   /sex="male"
FT                   /cell_line="lymphoblastoid"
FT                   /db_xref="taxon:9597"
FT   CDS             1..1608
FT                   /gene="ALDH5A1"
FT                   /product="succinic semialdehyde dehydrogenase precursor"
FT                   /function="GABA metabolism"
FT                   /EC_number="1.2.1.24"
FT                   /db_xref="GOA:Q3MSM4"
FT                   /db_xref="InterPro:IPR010102"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q3MSM4"
FT                   /protein_id="CAI69937.1"
FT                   /translation="MATCIWLRSCGARRLGWTFPGCRLRPRAGGLVPASGPAPGPAQLR
FT                   CYAGGLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRA
FT                   AYEAFCCWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFF
FT                   LEWFSEEARRVYGDIIYTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAG
FT                   CTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKIS
FT                   FTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTC
FT                   VCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDA
FT                   VSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAI
FT                   ANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGS
FT                   KYGIDEYLELKYVCYGGL"
FT   sig_peptide     1..141
FT                   /gene="ALDH5A1"
FT   mat_peptide     142..1605
FT                   /gene="ALDH5A1"
FT                   /product="succinic semialdehyde dehydrogenase"
FT                   /EC_number="1.2.1.24"
FT   3'UTR           1609..1638
FT                   /gene="ALDH5A1"
XX
SQ   Sequence 1638 BP; 360 A; 425 C; 489 G; 364 T; 0 other;
     atggcgacct gcatttggct gcggagctgt ggggcccggc gcctcgggtg gacgtttcca        60
     ggctgccgcc tccgcccccg cgccggcggc ctggtccctg cctccgggcc tgcgcccggc       120
     ccggcccagc tccgctgcta cgctgggggc ctggcgggcc tctctgcggc gctgctgcgc       180
     accgacagct tcgtgggcgg ccgctggctc ccggccgccg ccaccttccc cgtgcaagac       240
     ccggccagcg gcgccgctct gggcatggta gccgactgcg gggtgcgaga ggcccgcgcc       300
     gccgtgcgcg ctgcctacga ggctttctgc tgctggaggg aggtctcggc caaggagagg       360
     agttcattac ttcggaagtg gtacaattta atgatacaaa ataaggatga ccttgccaga       420
     ataatcacag ctgaaagtgg aaagccactg aaggaggcac atggagaaat tctctattcc       480
     gcctttttcc tagagtggtt ctctgaggaa gcccgccgtg tttacggaga cattatctac       540
     accccggcaa aggacaggcg ggccctggtc ctcaagcagc ccataggcgt ggctgcagtc       600
     atcaccccgt ggaatttccc cagtgccatg atcacccgga aggtgggggc cgccctggca       660
     gccggctgta ctgtcgtggt gaagcctgcc gaagacacgc ccttctccgc cctggccctg       720
     gctgagcttg caagccaggc tgggattcct tcaggcgtat acaatgttat tccctgttct       780
     cgaaagaatg ccaaggaagt aggggaggca atttgtactg atcctctggt gtccaaaatt       840
     tcctttactg gttcaacaac tacaggaaag atcctgttgc accacgcagc aaactctgtg       900
     aaaagggtct ctatggagct gggcggcctt gctccattta tagtatttga cagtgccaac       960
     gtggaccagg ctgtagcagg ggccatggca tctaaattta ggaacactgg acagacttgt      1020
     gtttgctcaa accaattctt ggtgcaaagg ggcatccatg atgcctttgt aaaagcattc      1080
     gccgaggcca tgaagaagaa cctgcgcgta ggtaatggat ttgaggaagg aactactcag      1140
     ggcccattaa ttaatgaaaa agcggtagaa aaggtggaga aacaggtgaa tgatgccgtt      1200
     tctaaaggtg ccaccgttgt gacaggtgga aaacgacacc aacttggaaa aaatttcttt      1260
     gagcctaccc tgctgtgcaa tgtcacccag gacatgctgt gcactcatga agagactttc      1320
     gggcctctgg caccagttat caagttcgat acagaggagg aggctatagc aatcgctaac      1380
     gcagctgacg ttgggttagc aggttatttt tactctcaag acccagccca gatctggaga      1440
     gtggcagagc agctggaagt gggcatggtt ggcgtcaacg aaggattaat ttcctctgtg      1500
     gagtgccctt ttggtggagt gaagcagtcc ggccttgggc gagaggggtc caagtatggc      1560
     attgatgagt atctggaact caagtatgtg tgttacgggg gcttgtagga ttctttggtt      1620
     ctttaaaaaa atttaaaa                                                    1638
//
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