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EBI DbfetchID AJ621752; SV 1; linear; mRNA; STD; MAM; 1638 BP. XX AC AJ621752; XX DT 22-JUL-2004 (Rel. 80, Created) DT 14-NOV-2006 (Rel. 89, Last updated, Version 4) XX DE Pan troglodytes mRNA for succinic semialdehyde dehydrogenase precursor DE (aldh5a1 gene) XX KW aldh5a1 gene; ssadh gene; ssdh gene; KW succinic semialdehyde dehydrogenase precursor. XX OS Pan troglodytes (chimpanzee) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Pan. XX RN [1] RP 1-1638 RA Malaspina P.; RT ; RL Submitted (22-JAN-2004) to the EMBL/GenBank/DDBJ databases. RL Malaspina P., Biology, Universita Tor Vergata, Via della Ricerca RL Scientifica, Rome, 00133, ITALY. XX RN [2] RA Blasi P., Malaspina P.; RT "Comparative analysis of succinic semialdehyde dehydrogenase in non three RT ape species"; RL Unpublished. XX RN [3] RX DOI; 10.1007/s00239-005-0154-8 RX PUBMED; 16786440. RA Blasi P., Palmerio F., Aiello A., Rocchi M., Malaspina P., Novelletto A.; RT "SSADH variation in primates: intra- and interspecific data on a gene with RT a potential role in human cognitive functions"; RL J. Mol. Evol. 63(1):54-68(2006). XX DR Ensembl-Gn; ENSPTRG00000017776; Pan_troglodytes. DR Ensembl-Tr; ENSPTRT00000062134; Pan_troglodytes. XX FH Key Location/Qualifiers FH FT source 1..1638 FT /organism="Pan troglodytes" FT /mol_type="mRNA" FT /db_xref="taxon:9598" FT CDS 1..1608 FT /gene="aldh5a1" FT /product="succinic semialdehyde dehydrogenase precursor" FT /function="GABA metabolism" FT /EC_number="1.2.1.24" FT /note="synonyms: ssdh, ssadh" FT /db_xref="GOA:Q6A2H0" FT /db_xref="InterPro:IPR010102" FT /db_xref="UniProtKB/Swiss-Prot:Q6A2H0" FT /protein_id="CAF21869.1" FT /translation="MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLR FT CYAGGLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRA FT AYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFF FT LEWFSEEARRVYGDIIYTPAKDRRALVLKQPXGVAAVITPWNFPSAMITRKVGAALAAG FT CTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKIS FT FTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTC FT VCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDA FT VSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAI FT ANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGS FT KYGIDEYLELKYVCYGGL" FT exon 1..354 FT /gene="aldh5a1" FT /number=1 FT sig_peptide 1..141 FT /gene="aldh5a1" FT mat_peptide 142..1605 FT /gene="aldh5a1" FT /product="succinic semialdehyde dehydrogenase" FT /EC_number="1.2.1.24" FT intron 354^355 FT /gene="aldh5a1" FT /number=1 FT exon 355..438 FT /gene="aldh5a1" FT /number=2 FT intron 438^439 FT /gene="aldh5a1" FT /number=2 FT exon 439..609 FT /gene="aldh5a1" FT /number=3 FT intron 609^610 FT /gene="aldh5a1" FT /number=3 FT exon 610..726 FT /gene="aldh5a1" FT /number=4 FT intron 726^727 FT /gene="aldh5a1" FT /number=4 FT exon 727..870 FT /gene="aldh5a1" FT /number=5 FT intron 870^871 FT /gene="aldh5a1" FT /number=5 FT exon 871..1014 FT /gene="aldh5a1" FT /number=6 FT intron 1014^1015 FT /gene="aldh5a1" FT /number=6 FT exon 1015..1173 FT /gene="aldh5a1" FT /number=7 FT intron 1173^1174 FT /gene="aldh5a1" FT /number=7 FT exon 1174..1343 FT /gene="aldh5a1" FT /number=8 FT intron 1343^1344 FT /gene="aldh5a1" FT /number=8 FT exon 1344..1402 FT /gene="aldh5a1" FT /number=9 FT intron 1402^1403 FT /gene="aldh5a1" FT /number=9 FT exon 1403..1608 FT /gene="aldh5a1" FT /number=10 FT 3'UTR 1609..1638 FT /gene="aldh5a1" XX SQ Sequence 1638 BP; 359 A; 427 C; 488 G; 362 T; 2 other; atggcgacct gcatttggct gcggagctgt ggggcccggc gcctcgggtc gacgtttcca 60 ggctgccgcc tccgcccccg cgccggcggc ctggtccctg cctccgggcc tgcgcccggc 120 ccggcccagc tccgctgcta cgctgggggc ctggcgggcc tctctgcggc gctgctgcgc 180 accgacagct tcgtgggcgg ccgctggctc ccggccgccg ccaccttccc cgtgcaagac 240 ccggccagcg gcgccgctct gggcatggta gccgactgcg gggtgcgaga ggcccgtgcc 300 gccgtgcgcg ctgcctacga ggctttctgc cgctggaggg aggtctcggc caaggagagg 360 agttcattac ttcggaagtg gtacaattta atgatacaaa ataaggatga ccttgccaga 420 ataatcacag ctgaaagtgg aaagccactg aaggaggcac ayggagaaat tctctattcc 480 gcctttttcc tagagtggtt ctctgaggaa gcccgccgtg tttacggaga cattatctac 540 accccggcaa aggacaggcg ggccctggtc ctcaagcagc ccrtaggcgt ggctgcagtc 600 atcaccccgt ggaatttccc cagtgccatg atcacccgga aggtgggggc cgccctggca 660 gccggctgta ctgtcgtggt gaagcctgcc gaagacacgc ccttctccgc cctggccctg 720 gctgagcttg caagccaggc tgggattcct tcaggcgtat acaatgttat tccctgttct 780 cgaaagaatg ccaaggaagt aggggaggca atttgtactg atcctctggt gtccaaaatt 840 tcctttactg gttcaacaac tacaggaaag atcctgttgc accacgcagc aaactctgtg 900 aaaagggtct ctatggagct gggcggcctt gctccattta tagtatttga cagtgccaac 960 gtggaccagg ctgtagcagg ggccatggca tctaaattta ggaacactgg acagacttgt 1020 gtttgctcaa accaattctt ggtgcaaagg ggcatccatg atgcctttgt aaaagcattc 1080 gccgaggcca tgaagaagaa cctgcgcgta ggtaatggat ttgaggaagg aactactcag 1140 ggcccattaa ttaatgaaaa agcggtagaa aaggtggaga aacaggtgaa tgatgccgtt 1200 tctaaaggtg ccaccgttgt gacaggtgga aaacgacacc aacttggaaa aaatttcttt 1260 gagcctaccc tgctgtgcaa tgtcacccag gacatgctgt gcactcatga agagactttc 1320 gggcctctgg caccagttat caagttcgat acagaggagg aggctatagc aatcgctaac 1380 gcagctgacg ttgggttagc aggttatttt tactctcaag acccagccca gatctggaga 1440 gtggcagagc agctggaagt gggcatggtt ggcgtcaacg aaggattaat ttcctccgtg 1500 gagtgccctt ttggtggagt gaagcagtcc ggccttgggc gagaggggtc caagtatggc 1560 attgatgagt atctggaact caagtatgtg tgttacgggg gcttgtagga ttctttggtt 1620 ctttaaaaaa atttaaaa 1638 // |
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