 |
|
EBI DbfetchID AJ242841; SV 1; linear; genomic DNA; STD; PRO; 12348 BP. XX AC AJ242841; XX DT 10-JUN-1999 (Rel. 60, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 7) XX DE Neisseria meningitidis DNA for opcA region, strain Z2491 XX KW abcZ gene; anthranilate synthase component I; ATP-binding protein; KW dedA gene; glyA gene; opcA gene; OpcA protein; orf1A-L; orf1A-R; orf1B; KW orfA; orfZ; phosphoribosyl aminoimidazole carboxylase; purK gene; KW serine hydroxymethyltransferase; trpE gene. XX OS Neisseria meningitidis OC Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; OC Neisseria. XX RN [1] RP 1-12348 RA Achtman M.; RT ; RL Submitted (04-JUN-1999) to the EMBL/GenBank/DDBJ databases. RL Achtman M., Abt. Trautner, Max-Plank-Institut fuer moleculare Genetik, RL Ihnestrasse 73, Berlin, 14195, GERMANY. XX RN [3] RX DOI; 10.1046/j.1365-2958.1999.01514.x RX PUBMED; 10417653. RA Zhu P., Morelli G., Achtman M.; RT "The opcA and (psi)opcB regions in Neisseria: genes, pseudogenes, RT deletions, insertion elements and DNA islands"; RL Mol. Microbiol. 33(3):635-650(1999). XX FH Key Location/Qualifiers FH FT source 1..12348 FT /organism="Neisseria meningitidis" FT /strain="Z2491" FT /mol_type="genomic DNA" FT /country="Gambia" FT /db_xref="taxon:487" FT CDS 350..1600 FT /transl_table=11 FT /gene="glyA" FT /product="putative serine hydroxymethyltransferase" FT /function="cell metabolism" FT /db_xref="GOA:Q9XAY7" FT /db_xref="HSSP:1DFO" FT /db_xref="InterPro:IPR019798" FT /db_xref="UniProtKB/Swiss-Prot:Q9XAY7" FT /protein_id="CAB44965.1" FT /translation="MFSKSVTLAQYDPDLAAAIAQEDQRQQDHVELIASENYVSCAVME FT AQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRVKKLFGAQYANVQPHSGSQANQA FT VYASVLKPGDTILGMSLAHGGHLTHGASVNISGKLYNAVTYGLDENEVLDYAEVERLAL FT EHKPKMIVAGASAYALQIDWAKFREIADKVGAYLFVDMAHYAGLVAGGEYPNPVPFCDF FT VTTTTHKTLRGPRGGVILCRDNTHEKALNSSIFPSLQGGPLMHVIAAKAVAFKEALQPE FT FKQYAKQVKINAAAMAEELVKRGLRIVSGRTESHVFLVDLQPMKITGKAAEAALGKAHI FT TVNKNAIPNDPEKPFVTSGIRIGSAAMTTRGFNEADARVLANLVADVLSNPEDEANLAK FT VREQVTALCNKYPVYGA" FT repeat_region 1728..4050 FT /mobile_element="insertion sequence:pseudo IS1106A2" FT /note="disrupted by the insertion of IS1106A3" FT CDS 1728..2170 FT /pseudo FT /transl_table=11 FT /product="putative transposase" FT /note="orf1A-L" FT repeat_region 2171..3401 FT /mobile_element="insertion sequence:IS1106A3" FT /note="inserted into pseudo-IS1106A2 in the opposite FT orientation" FT CDS complement(2325..3332) FT /transl_table=11 FT /product="putative transposase" FT /note="orf1B" FT /note="transposase of IS1106A3" FT /db_xref="GOA:Q9S361" FT /db_xref="InterPro:IPR002559" FT /db_xref="UniProtKB/TrEMBL:Q9S361" FT /protein_id="CAB44967.1" FT /translation="MSTFFRQTAQAMIAKHIDRFPLLKLDQVIDWQPIEQYLNRQKNRY FT LRDHRGRPAYPLLSMFKAVLLGQWHSLSDPELEHSLITRIDFNLFCRFDELIIPDYSTL FT CRYRNWLAQDDTLSELLKLINCQLTEKGLKIEKASAAVVDATIIQTAGSKQRQAIEVDE FT EGQISGQTTPSKDSDARWIKKNGLYKLGYKQHTRTDAEGYIEKLHITPANAHECKHLSP FT LLEGLPEGTTVYADKGYDSAENRQHLEEHQLLDGIMRKACRNRPLSEVQTKRNRYLSKT FT RYVVEQSFGTLHRKFRYARAAYFGLIKVSAQSHLKAMCLNLLKAANRLSAPAAA" FT CDS 3402..4050 FT /pseudo FT /transl_table=11 FT /product="putative transposase" FT /function="transposition" FT /note="orf1A-R" FT repeat_region 3784..3890 FT /note="CE16 Correia element" FT CDS 4638..5456 FT /transl_table=11 FT /gene="opcA" FT /product="OpcA protein" FT /function="outer membrane protein" FT /db_xref="InterPro:IPR009876" FT /db_xref="PDB:1K24" FT /db_xref="UniProtKB/TrEMBL:Q51227" FT /protein_id="CAB44969.1" FT /translation="MKKTVFTCAMIALTGTAAAAQELQTANEFTVHTDLSSISSTRAFL FT KEKHKAAKHIGVRADIPFDANQGIRLEAGFGRSKKNIINLETDENKLGKTKNVKLPTGV FT PENRIDLYTGYTYTQTLSDSLNFRVGAGLGFESSKDSIKTTKHTLHSSRQSWLAKVHAD FT LLSQLGNGWYINPWSEVKFDLNSRYKLNTGVTNLKKDINQKTNGWGFGLGANIGKKLGE FT SASIEAGPFYKQRTYKESGEFSVTTKSGDVSLTIPKTSIREYGLRVGIKF" FT sig_peptide 4638..4694 FT /gene="opcA" FT mat_peptide 4695..5453 FT /gene="opcA" FT /product="OpcA" FT CDS 5812..6264 FT /transl_table=11 FT /gene="dedA" FT /product="hypothetical protein" FT /db_xref="InterPro:IPR015414" FT /db_xref="UniProtKB/TrEMBL:Q9WW49" FT /protein_id="CAB44970.1" FT /translation="MDIHLMVALLSLAAILGDALNFTVGKYFGGRLFANPDSKIFRREY FT LDKTHRFYEKHGGKTIIIARFMPIVRTFAPFVAGMGKMHYAKFIRYNIIGGLLWVILFS FT YAGYFFANFPVVKNNLGLVMGGIIIVSVLPGAVEIARAKLAVKSKR" FT CDS 6283..8193 FT /transl_table=11 FT /gene="abcZ" FT /product="putative ATP-binding protein" FT /function="putative ABC transporter" FT /db_xref="GOA:Q9S360" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9S360" FT /protein_id="CAB44971.1" FT /translation="MNILSVENASFAVGHVALLDKTSFQLDSGEKIGLIGRNGAGKSSF FT LKILAGVQKLDDGQIIVQNNLKIVYVPQESFFDKEATVFDTVAEGLGEIRDLLRRYHHV FT SHELENGSSEALLKELNELQLEIEAKDGWKLDAAVKQTLGELGLPENEKIGNLSGGQKK FT RVALAQAWVQKPDVLLLDEPTNHLDIDAIIWLENLLKAFEGSLVVITHDRRFLDNIATR FT IVELDRGILRSYPGSFSKYSEKKAQELAVEAEHNRLFDKFHAQEEAWIRKGIEARRTRN FT EGRVRRLEELRRQRAERRNVQGQVNFKLDSGEKSGKIIAELEHASFTYGDKVIMDKFSA FT ILQRGDKIGLIGPNGIGKTTFLKLILGELQPTYGRIRIGSKQEVAYFDQFRSTLNENDT FT VFYTLGQGNDYVEVGGKKKHVMSYLEDFLFHPARAQSPVSSLSGGERNRLLLAKLFTRP FT ANILILDEPTNDLDIDTQELLEDLLRDYQGTVFLVSHDRMFLDNVITQSIIFEGNGRLK FT EYIGGYQDYIDAKSREAKIQTESAPKTADAEPVKEKPKANRTVKLSYKEQRELDALPDE FT IAALEAEQAEINAQLSDPEIFKDYEKAGALQSRAEEIEMLLLEKLERWELLETKQNGNA FT V" FT CDS 8214..8579 FT /transl_table=11 FT /product="hypothetical protein" FT /note="orfZ" FT /db_xref="UniProtKB/TrEMBL:Q9WW31" FT /protein_id="CAB44972.1" FT /translation="MFKRPEEIIVLILAVLWIAGTYFLAALFGADAYTVLKITALTLLW FT SAASFLLWQKNLSRHIWPLLLGCLTACWWPYLNQSVAPGSLPWYASWTFKTILALIPVT FT AGYLFKWKQYRQRKTKP" FT CDS 8690..10165 FT /transl_table=11 FT /gene="trpE" FT /product="putative anthranilate synthase component I" FT /function="biosynthesis of tryptophan" FT /db_xref="GOA:Q9XAZ0" FT /db_xref="HSSP:1K0E" FT /db_xref="InterPro:IPR015890" FT /db_xref="UniProtKB/Swiss-Prot:Q9XAZ0" FT /protein_id="CAB44973.1" FT /translation="MISKQEYQAQAAQGYNRIPLVQELLADLDTPLSLYLKLANRPYTY FT LLESVVGGERFGRYSFIGLPCSHYLKASGKHVDVYQNGEIVEQHDGNPLPFIEAFHNRF FT KTPEIPSLPRFTGGLVGYFGYETIYNFEHFAHRLKNTTKADPLGTPDILLMLSQELAVI FT DNLSGKIHLVVYADPSQPDGYERARERLEDIRTQLRQSCAIPLSLGSKHTEAVSEFGEE FT PFKACVNKIKDYIFAGDCMQVVPSQRMSMEFTDSPLALYRALRTLNPSPYLFYYDFGDF FT HIVGSSPEILVRRERDDVIVRPIAGTRLRGKTPAEDLANEQDLLSDAKEIAEHVMLIDL FT GRNDVGRISKTGEVKVTDKMVIEKYSHVMHIVSNVEGRLKDGMTNMDILAATFPAGTLS FT GAPKVRAMEIIEEVEPSKRGIYGGAVGVWGFNNDMDLAIAIRTAVVKNNTLYVQSGAGV FT VADSDPASEWQETQNKARAVIRAAQMVQEGLDK" FT CDS 10162..10707 FT /transl_table=11 FT /product="hypothetical protein" FT /note="orfA" FT /db_xref="InterPro:IPR012441" FT /db_xref="UniProtKB/TrEMBL:Q9XAY9" FT /protein_id="CAB44974.1" FT /translation="MTYEKLYELRQTLRPTTKDGLYTDNEKSREILTVRWSGNTENPKN FT FSAVAIGINPSKANDERSDKTLTQLARFLDMYGFTNFKMLNIFSSYSTQQTGIRANTQT FT DFSKFKGCLEDADMIILAWGTDRSAYKDEKNRILEFLKAEKFMEKVFCISETGNSSDTR FT HPSRISYSYQLVQFEESA" FT CDS 10704..11840 FT /transl_table=11 FT /gene="purK" FT /product="putative phosphoribosylaminoimidazole FT carboxylase" FT /function="purine nucleotide synthesis" FT /db_xref="GOA:Q9XAY8" FT /db_xref="HSSP:1B6R" FT /db_xref="InterPro:IPR005875" FT /db_xref="UniProtKB/TrEMBL:Q9XAY8" FT /protein_id="CAB44975.1" FT /translation="MKNISLSPPAMLGILGGGQLGRMFTVAAKTMGYKVTVLDPNPNAP FT AAEFADRHLCAPFDNQTALEELAKCAAVTTEFENVNADAMRFLAKHTNVSPSGDCVAIA FT QNRIQEKAWIRKAGLQTAPYQAICKAEDITEESIQFLPGILKTATLGYDGKGQIRVKTV FT DELKAAFAEHRGVDCVLEKMVDLRGEISVIVCRLNNDNVQTFDPAENIHENGILAYSIV FT PARLSADIQQQARQMAQRLADELNYVGVLAVEMFVVGDTHELVVNEIAPRPHNSGHHTV FT DACAADQFQQQVRLMCNLPPADTKLLSSCCMANILGDVWQEDGGEPDWFPLQSRPDAHL FT HLYGKKTAHKGRKMGHFTILSTDSDTAFQEAKKLHQSL" XX SQ Sequence 12348 BP; 3327 A; 3357 C; 2863 G; 2801 T; 0 other; ccaaacacag cattacaagc cattcatctg attttaagac atggtggggc aggagagttg 60 tcttggcaag tggtgtatca gcgggttatg gctgataaag atgtggttgg tgctggttat 120 ttgattgatt ttgcacaaac tgccgaaaat ttaccatttg atgcattgcc tttgggtagc 180 cttgtactaa cataaaggta atgagacgct aaaaaccagc atgttaaata aattacctga 240 taatgccaaa gaaaatttac gcattatgga ctatctgcct taggttttga agtatttttt 300 tatacaaaaa acactcatga taccctgatt acacaaagga gccgagaaca tgttttcaaa 360 aagcgttacc ctcgcacaat atgaccccga tttggcagca gccattgccc aagaagacca 420 acgccagcaa gaccacgtcg agctgattgc ctctgaaaac tacgtcagct gcgccgtaat 480 ggaagcgcaa ggttcccagc tgaccaacaa atacgccgaa ggctaccccg gcaaacgcta 540 ctacggcggc tgcgaatacg tcgatattgt cgaacaattg gcgattgacc gcgtcaaaaa 600 actgttcggc gcgcaatacg ccaacgtcca accgcactcc ggctcgcaag ccaaccaagc 660 cgtgtacgct tccgttttaa aaccaggcga caccattttg ggtatgtctc tggcgcacgg 720 cggccacctg acccacggcg cgagcgttaa tatctcaggc aaactctaca acgctgttac 780 ttatggtttg gatgaaaacg aagtgctcga ttatgccgaa gtcgaacgcc tcgcgctcga 840 acacaaaccc aaaatgattg tggcgggtgc gtctgcctac gcgttgcaaa tcgactgggc 900 aaaattccgc gaaatcgccg ataaagtcgg cgcatacctc tttgtcgata tggcgcacta 960 tgccggtctg gttgccggcg gcgaatatcc caatcccgtg ccgttctgcg acttcgttac 1020 caccaccacc cacaaaaccc tgcgcggtcc tcgcggcggc gtaattttgt gccgcgacaa 1080 tacccacgaa aaagcgttga actcttccat cttcccaagc ctgcaaggtg gcccgctgat 1140 gcacgttatc gccgccaaag ccgtggcgtt taaagaagca ttgcaacccg agttcaaaca 1200 atacgcaaaa caagtgaaaa tcaatgcagc cgccatggcg gaagagttgg ttaaacgcgg 1260 tttgcgcatc gtttccggcc gcaccgaaag ccacgttttc ctcgttgacc tgcaaccgat 1320 gaaaattacc ggcaaagccg ccgaagctgc tttgggcaaa gcgcacatca ctgtcaacaa 1380 aaacgccatc ccgaatgatc cggaaaaacc cttcgttacc tccggcatcc gcatcggttc 1440 cgccgccatg accacacgcg gttttaacga agccgacgcg cgcgtattgg cgaacttggt 1500 tgccgacgta ttgtctaacc ccgaagacga agccaacctc gccaaagtcc gcgaacaagt 1560 aactgctttg tgcaataaat accccgttta cggcgcgtaa gcctttttaa aaatattccg 1620 ctaagcaatc caatgccgcc tgaaatctca taatgtttca gacggaaacc tttgcaaaat 1680 tccccaaaat cccctaaatt cccaccaaga catttagggg attttccatg agcaccttct 1740 tccggcaaac cgcgcaagcc atgattgcca aacatatcaa ccgtttcccg ctattgaagt 1800 tggaccaagt gattgattgg cagccgatcg aaccatacct gaaccgtcaa agaacccgtt 1860 acctccgaga ccaccgcggt cgtcccgcct atcccctgct gtccatgttc aaagccgttc 1920 tgctcggaca atggcacagc ctctccgatc ccgaactcga acacagcctc atcacccgca 1980 tcgacttcaa cctgttttga cgttttgacg aactgagcat ccccgattac agcaccttat 2040 gccgctaccg caaccggcga cgcaagacga caccctgtcc gaattgccgg aactgatcaa 2100 ccgccaactg accgaaaaaa acctaaaaat agagaaagca tccgccgccg tcgttgacgc 2160 caccattatt cagaccgaga cctttgcaaa attcctttcc ctcccgacag ccgaaaccca 2220 aacacaggtt ttcggctgtt ttcgccccaa ataccgccta attctaccca aataccccct 2280 taatcctccc cggatacccg ataatcaggc atccgggctg ccttttaggc ggcagcgggc 2340 gcacttaacc tgttggccgc tttcaacagg ttcaaacaca tcgctttcag gtggctttgc 2400 gcactcactt taatcagtcc gaaataggct gcccgagcgt agcggaattt acggtgcagc 2460 gtaccgaagc tctgttcaac cacataacgg gtcttcgaca aatatcggtt gcgtttggtt 2520 tgcacttccg acagcgggcg gttgcggcag gctttgcgca taatgccgtc caacaactga 2580 tgttcttcca gatgttgccg gttttccgca ctgtcgtagc ctttgtcggc atagacggtc 2640 gtaccttcgg gtaacccttc caacaacggc gacaggtgtt tgcactcatg ggcattggcg 2700 ggagtaatgt gcagtttctc gatatagcct tccgcatcgg tacgtgtatg ttgtttgtaa 2760 ccgagtttgt agaggccgtt tttctttatc caacgggcat cgctgtcctt actcggtgtg 2820 gtttgaccgc tgatttgtcc ttcttcgtca acttctatgg cctgacgctg tttgctgccg 2880 gcggtctgga taatggtggc atcaacgacg gcggcggatg ctttctctat ttttaggcct 2940 ttttcggtca gttggcagtt aatcagtttg agtaattcgg acagggtgtc gtcttgcgcc 3000 agccagttgc ggtagcggca taaggtactg taatcgggga tgatcagttc gtcgaaacgg 3060 caaaacaggt tgaaatcgat gcgggtgatg aggctgtgtt cgagttcggg atcggagagg 3120 ctgtgccatt gtccgagcag gacggctttg aacatggaca gcagagggta ggcgggacgg 3180 ccgcggtggt ctctaaggta acggtttttt tgacggttca ggtattgttc gatcggctgc 3240 caatcaatca cctggtccaa cttcaatagc gggaaacggt cgatgtgttt ggcaatcatg 3300 gcttgtgcgg tttgccggaa gaaggtgctc atggaaaatc ccctaaatgg cttggtggga 3360 atttagggga ttttggggaa ttttgcaaag gtctcagacc gccggcagca aacagcgcca 3420 ggccatagaa gttgacgaag aaggacaaat cagcggccaa accacaccga gtaaagacaa 3480 agatgcccgt tggatctcta caaactcggt tacaaacaac atacccgtac cgatgcggaa 3540 ggctatatcg agaaactgca cattaccccc gccaatgccc atgagtgcaa acacctgccg 3600 ccgttgttgg aaggactgcc caaaggtacg accgtctatg ccgacaaagg ctacgacagt 3660 gcggaaaacc ggcaacatct ggaagaacat cagttgttgg acggcattat gcgcaaagcc 3720 tgccgcaacc gtccgctgtc ggaaacgcaa accaaacgca accggtattt gtcgaagacc 3780 cgttatagtg gattaaattt aaatcaggac aaggcgacga agccgcagac agtacaaata 3840 gtacggcaag gcgaggcaac gccgtactgg tttaaattta atccactata tgtggtcgaa 3900 cagagcttcg gtacgctgca ccgtaaattc cgctatgcgc gggcagccta tttcggactg 3960 attaaagtga gtgcgcaaag ccatctgaag gcgatgtgtt tgaacctgtt gaaagccgcc 4020 aacaagctaa gtgcgcccgc tgccgcctaa aaggagaccg gatgcctgat tatcgggtat 4080 ccggggaggg ttaagggggt atttgggtaa aattaggagg tatttggggc gaaaataaac 4140 gaaaacctgt gtttgggttt cggctgtcgg gagggaaagg aattttgcaa agatctcatc 4200 ctgttatttt cacaaaaaca gaaaaccaaa aacagcaacc tgaaattcgt cattcccgcg 4260 caggcgggaa tccagacccc caacgcggca ggaatctatc ggaaataacc gaaaccggac 4320 gaacctagat tcccgctttc gcgggaatga cggcagagtg gtttcagttg ctcccgataa 4380 atgccgccat ctcaagtctc gtcattccct taaaacagaa aaccgaaatc agaaacctaa 4440 aatttcgtca ttcccataaa aaacagaaaa ccaagtgaga ataacaattc gttgtaaaca 4500 aataactatt tgttaatttt tattaatata tgtaaaatcc ccccccccga aagcttaaga 4560 atataattgt aagcgtaacg attatttacg ttatgttacc atatccgact acaatccaaa 4620 ttttggagat tttaactatg aaaaaaacag tttttacatg tgccatgatt gccctgaccg 4680 gtactgccgc cgctgcacaa gagcttcaaa ccgctaatga gtttaccgtc cacaccgacc 4740 tctcttccat ttcttcaact cgtgctttcc tgaaagaaaa acacaaagct gccaaacaca 4800 tcggcgtacg tgctgatatt ccttttgatg ccaaccaagg catccgcttg gaagccggtt 4860 tcgggcgcag caaaaaaaat attattaatt tggaaacaga tgagaacaag ctgggtaaga 4920 ctaaaaatgt aaaactgccc accggcgttc ctgaaaaccg tatcgatctt tacacaggct 4980 acacctacac ccaaacgtta agtgattctt taaatttccg tgtgggtgcc ggcttgggtt 5040 ttgaatcttc aaaagacagc attaaaacca ccaagcatac gcttcacagc agccgtcagt 5100 cgtggttagc caaagttcac gcggatttgc tttcccaact gggtaacggc tggtatatca 5160 acccttggtc tgaagtgaaa tttgacctca attcccgcta taaattaaac accggcgtta 5220 ccaatctcaa aaaagacatc aatcaaaaaa ccaacggctg gggctttgga ttgggtgcaa 5280 atattggtaa aaaactgggc gaatccgcca gcatcgaggc ggggccgttc tacaaacaac 5340 gcacttacaa agaatccggc gagtttagtg taacaaccaa gagtggcgac gtatcgctca 5400 ccatcccgaa aaccagtatt cgtgaatacg gcttgcgcgt cggcataaaa ttctgatgat 5460 ttgaaatcat cattgtcact ttaaatgcca aaccgcaaac tattttggtt tgcggttttt 5520 acgtgaaatg aatttgaata gccgatgccg tctgaaaatt tcagacggca tttttccaat 5580 cggttaaaat acgcggtttg ttttttttag gaacgcgccg tgcttgcctc cgccatcgac 5640 ttcatcctcc atatcgacca acacctgctc gcgctgtcgg cgcaatacgg tgtgtggatt 5700 tatgcgattc tgtttttgat tgttttttgc gaaaccggcc tgattgttac gcccttactg 5760 cccggcgatt cgctgctgtt tgccgccggc ggtattgccg cgctgggcgg tatggatatt 5820 catttgatgg ttgcattatt aagccttgcc gccatactcg gcgacgcgct caattttacc 5880 gtcggcaaat atttcggcgg caggctgttc gccaatcccg attctaaaat cttccgacgt 5940 gaatatctcg ataaaaccca ccgtttttac gaaaaacacg gcggcaaaac catcatcatt 6000 gcccgtttta tgcccatcgt ccgcaccttc gcccccttcg tcgccggtat ggggaaaatg 6060 cactatgcca aatttatccg ctacaacatc atcggtggct tgttgtgggt tatcctgttt 6120 tcttacgcgg gctatttctt tgccaacttc cccgtcgtaa aaaacaatct gggcttggtg 6180 atgggcggca tcattattgt ttccgtcctg ccgggtgcgg ttgaaattgc ccgcgccaaa 6240 cttgcggtaa aatccaaacg gtaactgttg agaatttgta tcatgaatat attatctgta 6300 gaaaacgctt cctttgccgt cggccacgtc gccctgctcg acaaaacttc cttccaactc 6360 gacagcggcg aaaaaatcgg cttaatcggt cgtaatggtg cgggtaagtc ttcgttttta 6420 aaaatcctcg ccggcgtgca aaagcttgat gatgggcaga ttattgtcca aaacaacctc 6480 aaaatcgttt atgtaccgca ggaatccttt tttgataagg aagcaaccgt atttgatact 6540 gttgccgaag gtttgggcga aattcgcgat ttattgcgcc gttatcatca tgtcagccat 6600 gagttggaaa atggttcgag tgaggcctta ttgaaagagc tcaacgaatt gcaacttgag 6660 atcgaagcga aggacggctg gaagttggat gcggcggtga agcagacttt gggcgaactc 6720 ggtttgccgg aaaacgaaaa aatcggcaac ctctccggcg gtcagaaaaa gcgcgtcgcc 6780 ttggcgcagg cttgggtgca gaagcccgac gtattgctgc tcgatgaacc gaccaaccat 6840 ttggacatcg acgcgattat ttggttggaa aacctgctca aagcgtttga aggcagcctg 6900 gttgtgatta cccacgaccg ccgttttttg gacaatatcg ccacgcggat tgtcgaactc 6960 gatcgcggta ttttgcgttc ctatcccggc tcgttctcca aatatagcga gaaaaaagcg 7020 caagagttgg cagtcgaagc ggaacacaac cgcctcttcg acaaattcca cgcgcaggaa 7080 gaagcgtgga tacgcaaagg catcgaagcg cgccgtaccc gcaacgaagg ccgcgtgcgc 7140 cgtttggaag aactgcgccg ccagcgtgcc gaacgccgca acgtacaagg gcaggtcaat 7200 ttcaagctcg acagcggcga gaaaagcggc aaaatcattg ccgaactgga acatgcctcg 7260 tttacctatg gcgacaaagt catcatggac aaattctccg ccatcttgca gcgtggcgac 7320 aaaatcggct taatcggccc aaacggtatc ggcaaaacca ccttcctcaa gctgattttg 7380 ggcgaattgc agccgaccta cggcagaatc cgtatcggca gtaagcagga agttgcctat 7440 ttcgaccaat tccgcagcac gttgaacgaa aacgacaccg tgttttacac gctcggtcaa 7500 ggcaacgatt acgtcgaagt cggcggcaag aaaaaacacg taatgagcta tctggaagat 7560 ttcttattcc atccagcccg cgcacaaagt cccgtttcat cgctctccgg cggcgaacgc 7620 aaccgccttt tgctggcaaa actctttacc cgtcctgcta atattttgat tttggacgaa 7680 ccgaccaacg acttggatat cgatacccaa gagctgcttg aagatttgct gcgcgattat 7740 caaggcacgg tattccttgt ctcacacgac cgtatgttcc tcgataacgt gattacccaa 7800 agcattattt ttgaaggaaa tggaaggtta aaagaatata tcggcggcta tcaggactac 7860 atcgacgcaa aatcacgcga agcgaagatt cagacggaat ccgcacccaa aacagccgat 7920 gccgaaccgg tgaaagaaaa acccaaagcc aaccgcacgg tcaaactgtc ctacaaagaa 7980 cagcgcgaac tcgacgccct gcccgacgaa atcgccgcct tggaagccga acaggcagaa 8040 atcaacgcgc agctttccga tcccgaaatc ttcaaagatt acgaaaaagc cggcgcactg 8100 caaagccgcg ccgaagaaat cgaaatgctg cttttggaaa agctggaacg ctgggagctg 8160 ctggaaacca aacagaacgg caatgccgtc tgaaatcaaa caggaagaaa aaaatgttca 8220 aacgacctga agaaatcatt gtcctgatac ttgccgtcct ctggattgcc ggtacgtatt 8280 ttctcgccgc cctgtttgga gcggatgctt ataccgtgtt aaaaatcact gcccttaccc 8340 tgctttggtc tgccgcatca ttcctccttt ggcaaaaaaa cctcagccgg catatctggc 8400 cgctgctgct cggctgcctg actgcctgtt ggtggccgta tctgaatcaa tcggtcgcac 8460 ccggttcttt accttggtat gcatcatgga cgttcaaaac catcttagcc ctgattcccg 8520 taaccgcagg ttatctgttt aaatggaaac aataccggca gcgcaaaaca aagccgtaag 8580 cccgtccttt tcagacggca tctccggtca gactgtcaac aattccgata aaatgctata 8640 ctcgcgcccg ttgccgcgcc gtccgaaacc gccctttggg aaagcagaaa tgatcagcaa 8700 acaagaatac caagcccaag ccgcccaagg ctacaaccgc atcccgctcg tgcaagaact 8760 ccttgccgat ttggatacgc cgctttccct ctatctcaaa ctcgccaacc gcccctatac 8820 ctacctgctc gaatccgttg tcggtggcga acgtttcggc cgctattctt ttatcggcct 8880 gccttgcagc cactatctca aagccagcgg caaacacgtc gatgtttatc aaaacggcga 8940 aattgtcgag caacacgacg gcaaccccct gccctttatc gaagccttcc acaaccgctt 9000 caaaacaccc gaaatcccaa gcctgccgcg ctttaccggc ggactggtcg gctacttcgg 9060 ttacgaaacc atctacaatt ttgaacactt cgcccaccgc ctgaaaaaca ccaccaaagc 9120 cgacccgctc ggcacgcccg acatcttgct gatgctgtcg caagaattgg cggtgatcga 9180 caatttgagc ggcaaaatcc atctcgtcgt ttacgccgat ccgtcgcagc ccgacggcta 9240 cgaacgcgcc cgcgaacgcc tcgaagacat ccgcacccag ttgcgccaaa gctgcgccat 9300 cccgctctcg ctcggcagca aacacaccga agccgtcagc gaattcggcg aagagccgtt 9360 caaagcctgc gttaacaaaa tcaaagacta catcttcgca ggcgactgca tgcaggttgt 9420 ccccagccag cgcatgagca tggaattcac cgacagcccg ctcgccctct accgcgccct 9480 gcgtacgctc aacccttcgc cttatctctt ttactacgat ttcggcgatt tccacatcgt 9540 cggctcctcg cccgaaatcc tcgtccgccg cgaacgcgac gatgtcatcg tccgccccat 9600 cgccggcacg cgcctgcgcg gcaaaacccc cgccgaagac cttgccaacg aacaagattt 9660 gttaagcgat gccaaagaaa tcgccgaaca cgtcatgttg attgacttag gacgcaacga 9720 cgtcggccgc atcagtaaaa ccggcgaagt caaagttacc gacaaaatgg tgattgaaaa 9780 atactcccat gtaatgcaca tcgtttccaa cgtcgaaggc cgtctgaaag acggcatgac 9840 caacatggac atcctcgccg ctaccttccc tgccggcaca ctctccggcg cacccaaagt 9900 ccgcgccatg gaaatcatcg aagaagtcga accgagcaaa cgcggcatct acggcggtgc 9960 cgtcggcgta tggggtttca acaacgacat ggatttggca atcgccatcc gcaccgccgt 10020 agtaaaaaac aacacgctat acgtccaaag cggcgcgggc gtggttgccg actccgatcc 10080 ggcctccgaa tggcaggaaa cacaaaacaa agcccgagcc gttatacgcg ccgcgcagat 10140 ggtgcaggaa gggttggata aatgacttat gaaaaacttt atgagcttcg ccaaacactc 10200 agaccgacta ccaaagacgg tctctataca gataatgaaa aaagtcgaga aatcctaacg 10260 gttagatgga gcggcaacac agaaaatcct aaaaatttct cagctgttgc tataggaatt 10320 aatccaagta aagcaaatga tgaaagaagc gacaaaaccc ttacccaact tgcacgtttc 10380 ttggatatgt acggttttac caacttcaaa atgttaaata ttttttccag ttactctaca 10440 cagcaaacag gaattagggc aaacacccaa accgattttt ccaaatttaa aggatgtttg 10500 gaagatgctg atatgattat tcttgcatgg ggtacagacc gcagtgctta taaggatgaa 10560 aaaaacagaa tactggaatt tctaaaagca gaaaaattta tggaaaaagt attctgtatt 10620 tctgaaactg gtaattccag cgatacaaga catccgtcaa gaattagtta tagctatcaa 10680 cttgtacaat ttgaagagtc agcatgaaaa acatatctct ttctccgccc gccatgctcg 10740 gcattcttgg cggcggacaa ttaggcagaa tgtttactgt tgctgccaaa accatgggct 10800 acaaagtaac cgtactcgat cccaacccga atgcgccggc agcggaattt gccgaccgcc 10860 atttgtgtgc gccgtttgac aaccaaaccg ctttggaaga attggcaaaa tgtgcggctg 10920 ttacgaccga gttcgaaaac gtcaatgccg atgcgatgcg ttttctcgcc aaacatacca 10980 atgtttcccc cagcggcgac tgcgttgcca tcgcgcaaaa ccgcattcag gaaaaggcat 11040 ggatacgcaa agcaggcctg caaaccgcgc cgtatcaagc aatttgcaaa gccgaagaca 11100 tcactgaaga aagcatacaa tttctgcccg gcatcctgaa aaccgctaca ttgggctatg 11160 acggcaaagg ccaaatccgc gtcaaaacgg tggatgaact caaagccgcg tttgccgaac 11220 accgcggcgt ggattgcgtt ttggaaaaaa tggtggactt gcgcggcgaa atttccgtta 11280 tcgtatgccg tctgaacaat gacaacgtgc aaactttcga tcctgccgaa aacattcacg 11340 aaaacggtat cctcgcctac tccatcgtcc cagcccgact gagtgccgac attcagcaac 11400 aggcgcgaca aatggcgcag cgtttggccg atgaattgaa ctacgtcggc gtattggcgg 11460 tagaaatgtt tgttgtcggc gacacgcatg aattggtcgt caacgaaatc gcgccgcgtc 11520 cgcacaattc cggccaccat accgtcgacg cctgcgcggc agaccaattc cagcaacagg 11580 tccgcctgat gtgcaacctg ccacctgctg acaccaaatt gctgagttct tgctgtatgg 11640 cgaatatttt gggcgacgtt tggcaggaag acggcggcga accggattgg tttcccctgc 11700 aaagccggcc ggacgcgcac ctgcaccttt acggcaaaaa aaccgcgcac aaagggcgga 11760 aaatgggaca ctttaccatt ttaagcaccg attcggacac cgcatttcaa gaagcaaaaa 11820 aactgcatca gtccctataa tccgaccaac ggcacagatg ccgtctgaag ccgccgacat 11880 actgccatga acctgctgac actgttacgc cccgccaccg tgcaagactg caaagacatc 11940 ttcaaagtcc acctgcactc cgtccaatac acctgcatcc tcagctacaa cgaacacgcc 12000 ctaaaagtat gggaaggctt gttaaacaca gaaagctacc tgccgaccat ttccgatccc 12060 gacaaagcac tttgggttgc cgaatacaaa ggcaacatac agggattttt ccaaatcgag 12120 tgccaagaag cacaactcga tgcactttac gtccaccccc tgttccacaa cctcggactg 12180 ggcactgccc tgcttcatca ggcggaaacc atcgcccaca aatccggttt gagctttctg 12240 aaactttacg catcgctcaa ctccgtcccg ttttaccttt tcaaccggta cgaatcgctc 12300 ggttcggcag tattgcagtt tgaccccagc atcaaaatca aatgcgaa 12348 // |
|