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EBI DbfetchID AJ239004; SV 1; linear; genomic DNA; STD; PRO; 14730 BP. XX AC AJ239004; XX DT 26-MAY-1999 (Rel. 59, Created) DT 15-APR-2005 (Rel. 83, Last updated, Version 4) XX DE Streptococcus pneumoniae type 8 capsular gene cluster XX KW aliA gene; alpha,1-6-glucosidase; cap8A gene; cap8B gene; cap8C gene; KW cap8D gene; cap8E gene; cap8F gene; cap8G gene; cap8H gene; cap8I gene; KW cap8J gene; cap8K gene; cap8L gene; dexB gene; galactosyltransferase; KW glucuronic acid transferase; oligopeptide permease; KW polysaccharide polymerase; putative transposase; KW Undecaprenyl-phosphate glucose 1-phosphate transferase; KW uridine diphosphate glucose dehydrogenase. XX OS Streptococcus pneumoniae OC Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus. XX RN [1] RP 1-14730 RA Munoz R.; RT ; RL Submitted (25-MAY-1999) to the EMBL/GenBank/DDBJ databases. RL Munoz R., Microbiologia Molecular, Centro de Investigaciones Biologicas. RL CSIC, Velazquez 144, Madrid 28006, Spain. XX RN [2] RX PUBMED; 10498742. RA Munoz R., Mollerach M., Lopez R., Garcia E.; RT "Characterization of the type 8 capsular gene cluster of Streptococcus RT pneumoniae"; RL J. Bacteriol. 181(19):6214-6219(1999). XX FH Key Location/Qualifiers FH FT source 1..14730 FT /organism="Streptococcus pneumoniae" FT /mol_type="genomic DNA" FT /db_xref="taxon:1313" FT CDS <1..765 FT /transl_table=11 FT /gene="dexB" FT /product="alpha, 1-6-glucosidase" FT /db_xref="GOA:Q9RIN3" FT /db_xref="HSSP:1UOK" FT /db_xref="InterPro:IPR006047" FT /db_xref="InterPro:IPR013780" FT /db_xref="InterPro:IPR013781" FT /db_xref="InterPro:IPR017853" FT /db_xref="UniProtKB/TrEMBL:Q9RIN3" FT /protein_id="CAB43603.1" FT /translation="LNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQE FT YREKSAKAFAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVP FT MQEIMDSIRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIF FT YTYQKLVQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEG FT KVKSVLIENTLAQEVFEKQILVPWDAFCVELL" FT CDS complement(1088..1411) FT /transl_table=11 FT /product="putative transposase" FT /db_xref="UniProtKB/TrEMBL:Q9X997" FT /protein_id="CAB44496.1" FT /translation="MNGELIAPMTYEETMTSDFFEAWFQKFLLPTLTTPSVIIMDNARF FT HRMGKLELLCEEFRRKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCS FT CFN" FT terminator 1114..1171 FT CDS complement(1589..1954) FT /transl_table=11 FT /product="putative transposase" FT /db_xref="InterPro:IPR002622" FT /db_xref="InterPro:IPR009057" FT /db_xref="UniProtKB/TrEMBL:Q9X998" FT /protein_id="CAB44497.1" FT /translation="MRYNLLMAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWL FT KLKEKTGELNHQVKGTKPRKVDRDRLKNYLTDNPDAYLTEIASNLAVIQLPSTMRSKLW FT ATLEKRTTPTMNKTQKK" FT -35_signal 2130..2135 FT -10_signal 2152..2158 FT CDS 2189..3634 FT /transl_table=11 FT /gene="cap8A" FT /db_xref="GOA:Q9X999" FT /db_xref="InterPro:IPR004190" FT /db_xref="InterPro:IPR004474" FT /db_xref="UniProtKB/TrEMBL:Q9X999" FT /protein_id="CAB43604.1" FT /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAFR FT YLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNRLN FT ATSNYSEYSLSVALLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLTVDQ FT SSSYLVAYKSLIAGETKAIVLNSVFENIIELEYPDYASKIKKIYTKGFTKKVEAPKTSK FT NQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTSRDAYVPIADGGNNQK FT DKLTHAGIYGVDSSIHTLENLYGVDINYYVLLNFTSFLKMIDLLGGVDVHNDQEFSALH FT GKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTSTEVLKNYS FT TIINSLQDSIQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSYAMPDSNLY FT MMEIDDSSLAVVKAAIQDVMEGR" FT CDS 3636..4367 FT /transl_table=11 FT /gene="cap8B" FT /db_xref="GOA:Q9RIN2" FT /db_xref="InterPro:IPR004013" FT /db_xref="InterPro:IPR016667" FT /db_xref="UniProtKB/TrEMBL:Q9RIN2" FT /protein_id="CAB43605.1" FT /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRRK FT GMFETPEEKIAESFLQVREIAKEVADDLVIAYGAEIYYTPDVLDKLGKKRIPTLNDSRY FT ALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALGNNEKRVRELIDMGCYTQVN FT SSHVLKPKLFGERYKFMKKRAQYFLEQTLVHVIASDMHNLDGRPPHMAEAYDFVTQKYG FT EAKAQELFIDNPRKIIMDQLI" FT CDS 4373..5068 FT /transl_table=11 FT /gene="cap8C" FT /db_xref="GOA:Q9X9A0" FT /db_xref="InterPro:IPR003856" FT /db_xref="InterPro:IPR005701" FT /db_xref="UniProtKB/TrEMBL:Q9X9A0" FT /protein_id="CAB43606.1" FT /translation="MMKEQNTIEIDVFQLFKTLWKRKLMILLVALVTGAGAFAYSTFIV FT KPEYTSTTRIYVVNRNQGDKSGLTNQDLQAGSYLVKDYREIILSQDALEKVATNLKLDM FT PAKTLASKVQVTVPTDTRIVSISVKDKQPEEASRIANSLREVAVEKIVAVTRVSDVTTL FT EEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLQIPLLG FT LVPDLDKMK" FT CDS 5078..5767 FT /transl_table=11 FT /gene="cap8D" FT /db_xref="GOA:Q9X9A1" FT /db_xref="InterPro:IPR005702" FT /db_xref="UniProtKB/TrEMBL:Q9X9A1" FT /protein_id="CAB43607.1" FT /translation="MPTLEISQAKLDFVKKAEEYYNSLCMNLQLSGGGLKVFSITSVKL FT GEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDLSQ FT GLCDTNIENLFVIQAGSVSPNPTALLQSKNFTTMLETLRKYFDYIIVDTAPVGVVIDAA FT IITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVNKYGSYGNYG FT DYGKNKK" FT CDS 5782..7149 FT /transl_table=11 FT /gene="cap8E" FT /product="Undecaprenyl-phosphate glucose 1-phosphate FT transferase" FT /db_xref="GOA:Q9X9A2" FT /db_xref="InterPro:IPR003362" FT /db_xref="InterPro:IPR017475" FT /db_xref="UniProtKB/TrEMBL:Q9X9A2" FT /protein_id="CAB43608.1" FT /translation="MNGKVVNSSLAIIHSFLVILLTYLLSAVREAEIASATAIALYILH FT YFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYFLT FT LHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGELVAV FT SVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMGIDVT FT VNLNAFDRSLARNKQIREMAGLNVVIFSTTFYKTSHVIAKRIIDIVGALVGLILCGLVS FT VVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMCVDAEDKKRELMEQNTMQGGMFK FT VDDDPRITKVGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYKHYTPEQKRRLSF FT KPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLMKDGAK" FT CDS 7136..7633 FT /transl_table=11 FT /gene="cap8F" FT /db_xref="InterPro:IPR013969" FT /db_xref="UniProtKB/TrEMBL:Q9X9A3" FT /protein_id="CAB43609.1" FT /translation="MERSKGMKNKKKVCFCASSGGHYEQLMKLEPIMRQQDSYLITEYT FT DYNKGESEKKDINKVFYLLQINRLEFFWIVKLIWISLKSLYILLRIRPKVVICTGVLAM FT IPFCLLSKMFGAKLIYIESFAKVTTPTLTGRILYRYADRFYVQWESMLDIYPNAVYKGG FT LY" FT CDS 7634..8113 FT /transl_table=11 FT /gene="cap8G" FT /product="glucuronic acid transferase" FT /db_xref="GOA:Q9X9A4" FT /db_xref="InterPro:IPR007235" FT /db_xref="UniProtKB/TrEMBL:Q9X9A4" FT /protein_id="CAB43610.1" FT /translation="MIFITVGTQKHPFNRLLKKIDQLIELEVIKEEVFAQIGASDYKPK FT YFSYNSFLSSIDMNEKVREASMVIIHGGTASIVKALKLRKKIIAVPRLEQFGEHVDNHQ FT LQIITVLGEEGYILPCFDIEQLGTVYQKAQTFTTKPYISNSYALLEDIRQYIDSL" FT CDS 8126..9190 FT /transl_table=11 FT /gene="cap8H" FT /product="galactosyl transferase" FT /db_xref="GOA:Q9X9A5" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q9X9A5" FT /protein_id="CAB43611.1" FT /translation="MTKVLQIGPSINLSKGGMSAVIRDLTYSPLLSGDFDITAYQSFID FT GSLVTRLTYSSYALLKFVVHSGNYDIYHIHTATRGSCWRKLLYLKLLKSKNKKAILHIH FT GAEFQIFYDSLPEYKKNKVREMLELSDYVIVLSQTWYDFFSNININAKIVIVENGVDTS FT FYVEKKKSITSNNFLFLGRMGKRKGAYDLIDAMNQAVAINPNLHLTMAGDGELEDIRQK FT ISNLNLTDHITIYDWVNQRDKKILFQANQTLILPSYNEGLPMAILEAMASGLAIISTPV FT GGIPEIIHEDNGWLIQPGDISQLSNIILEASYNPDVVSLMGSNNHKLVEEKYSFHSMHG FT KIKKIYNTLLETKK" FT CDS 9190..10650 FT /transl_table=11 FT /gene="cap8I" FT /product="oligosaccharide repeat unit transporter" FT /db_xref="GOA:Q9X9A6" FT /db_xref="InterPro:IPR002528" FT /db_xref="InterPro:IPR002797" FT /db_xref="UniProtKB/TrEMBL:Q9X9A6" FT /protein_id="CAB43612.1" FT /translation="MTKKSITRNFIFNTILTMSSFIFPLISFPYVSRVLMADGLGRVTF FT ASSIIDYALTFAMLGMPLYGVKVCAGYIKNKEKLSQTVRELLVINLLVGFLVMLLLATM FT VIIIPRFRQEWQLIIITSSTIPLNIIGIEWLYKALEDYSYISIRTLTFKILGFLLMFLV FT VRTKDDYMVYAAITVLASHGSFILNFFRSRTFLLENISQRLNLKQHIKPLLILFFLSVS FT WTIYKNTDVVMMGFLTSDTEIGYYSTALKIRSIVLSVVTSLGTVVLPRLVKYYKEGKYN FT EAKKILNKSSSFIMLSSLYFIGYIVINAREIILFIAGRNYLGAIPTLQVSIFSAIFVGY FT SIMYGTNILVSIGKENVTIQASIIGVVLNICLNFIMIPKFAALGAGIATSIGEAVMVLY FT EIIYLGKDGWSYFERLNILKIIVVFIFSTFMLYIMKDFFVGYPLFIYIVISGVIYSIIY FT IFGLMILRENLLSSWKISILNRFNIIKE" FT CDS 10663..11391 FT /transl_table=11 FT /gene="cap8J" FT /db_xref="InterPro:IPR007577" FT /db_xref="UniProtKB/TrEMBL:Q9X9A7" FT /protein_id="CAB43613.1" FT /translation="MIPKKIHYIWFGGSEKPDVVLKCINSWKKYMPDYEIVEWNEDNFD FT LSDSQFAKSAYESRKWAFASDYARFKILSKYGGIYFDTDVELLKTISDDILAHSSFTGF FT EYIGEVNPGLVYACMPDDKIAKYMVQYYEQASFDINHLVTVNTIITDYLLKNNFQKNNQ FT FQIIDGLAIYPDDYFCGYDQEVKEVRLTERTISIHHYSATWKTRTLKRKVQMIVKTIIG FT AENYRKLLYCKRKITNAVSK" FT CDS 11375..12538 FT /transl_table=11 FT /gene="cap8K" FT /product="polysaccharide polymerase" FT /db_xref="UniProtKB/TrEMBL:Q9X9A8" FT /protein_id="CAB43614.1" FT /translation="MPYLNNVPQNKFSIRLFDIAIVLLTLKMLVSSIPVFDFVFPQKFQ FT NILVILGYILIFLHIFEKRKYTLQFIISIILITTLLLYTSIQMQNYVYFTSWFMLIGTI FT HYDLRRVIKIIFIVSLSIMFISIFISLLMYIIDYKREILINIRRNETVRAFTFGFIHPN FT KFTIVLSNLCLMFIWLIKDRLKYYHVTFCLFIQLFFYFFTQTRTALLVSIVIFALLYIY FT MFVENLELRWIGYSFFCISTFLGVLAFQFYPSNNKFSIFIDNILTGRIKLAAYARTFFG FT YTFWGQYVDKEIVWDPIWGLTSFTFDSFYSFLMSNAGIIWLLILSVLFVKLQKYLDNKS FT LILLLAWSMYAVTETDLIFPSYGFQFLFLSILFTNTSTCSTIMLKNN" FT CDS 12607..13845 FT /transl_table=11 FT /gene="cap8L" FT /product="uridine diphosphate glucose dehydrogenase" FT /db_xref="GOA:Q9X9A9" FT /db_xref="HSSP:1DLJ" FT /db_xref="InterPro:IPR001732" FT /db_xref="InterPro:IPR006168" FT /db_xref="InterPro:IPR008927" FT /db_xref="InterPro:IPR014026" FT /db_xref="InterPro:IPR014027" FT /db_xref="InterPro:IPR014028" FT /db_xref="InterPro:IPR016040" FT /db_xref="InterPro:IPR017476" FT /db_xref="UniProtKB/TrEMBL:Q9X9A9" FT /protein_id="CAB43615.1" FT /translation="MKIAVTGTGYVGLSIAVLLAQHHQVIAVDIIPEKVELINQRKSPI FT QDDYIEKYLAEKDLNLVATLDAKEAYKDADFVVIAAPTNYDPKKNFFDTSAVESVIETV FT LKYNPDAIMVIKSTVPVGYTESARKKFQTENILFSPEFLRESKALYDNLYPSRIILGTD FT KNNERLVSVAETFAGLLQEGALKEDIDTLYMGFTEAEAVKLFANTYLALRVSYFNELDT FT YSEMKGLDTQAIIDGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYEDVPEELIGA FT IVRSNSTRKDFIADQVLKMVDSYDYSAHNVFNERVEKDIIIGIYRLTMKSNSDNFRQSS FT IQGIMKRIKAKGVRVVIYEPTLESGSTFFGSSIINDLEEFKRLSNAIVANRYDNSLEDV FT KEKVYTRDIFERD" FT CDS 14417..>14730 FT /transl_table=11 FT /gene="aliA" FT /product="oligopeptide permease" FT /db_xref="GOA:Q9RIN1" FT /db_xref="HSSP:1DPE" FT /db_xref="InterPro:IPR000914" FT /db_xref="UniProtKB/TrEMBL:Q9RIN1" FT /protein_id="CAB43616.1" FT /translation="MMKSSKLFALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETDP FT DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDAK FT " XX SQ Sequence 14730 BP; 4741 A; 2219 C; 2903 G; 4867 T; 0 other; ctgaatatcg ctaagttaaa agaaatcttc aacaaatggc agacagagtt aggagttgag 60 gacggctgga attccctctt ctggaacaac catgacctcc ctcgtattgt ctcaatctgg 120 ggaaatgacc aagaataccg cgaaaaatct gccaaagcct ttgcaatctt acttcatctc 180 atgagaggaa ctccttatat ctaccaaggt gaggagattg ggatgaccaa ctatccgttt 240 gaaacactag atcaagtaga agatattgaa tctctcaact atgcgcgtga ggctcttgaa 300 aaaggtgttc cgatgcaaga aatcatggac agtatccgtg ttattggacg tgacaatgcc 360 cgtaccccta tgcaatggga cgagagcaaa aacgctggtt tctcaacagg tcaaccttgg 420 ttggcagtta atccaaatta cgagatgatc aacgtccaag aagcgctggc aaatccagat 480 tctattttct atacctatca gaaactggtc caaattcgca aggagaatag ctggctaatt 540 cgagctgact ttgaattgct tgatacggct gataaggtct ttgcttatat acgtaaggat 600 ggcgaccgtc gcttcctagt tgtggctaac ttgtccaatg aagagcaaga cttgacagta 660 gaaggaaaag tcaaatctgt cttgattgaa aacaccctag ctcaagaagt ttttgaaaaa 720 caaatcttag ttccatggga tgctttctgt gtggaattac tataaatatt ttttgcagaa 780 aaatttaaat tgaaatcata taaaaacaag gaggactgta taaaaagcag aaatcctttg 840 ttttttataa ccaaggttta taaactttca ttttcgaaat tcaattaact ttacaaattc 900 ccactattaa ggagaaagaa gatgaacata aagaagcgtg ttcttagtgc aggcctgact 960 tttgcatctg ctttgctttt agctgcttgc ggccaatcag gctcagatac aaaaacttac 1020 tcatcaacct ttagtggaaa tccaactaca tttaactatc tattagacta ttacgctgat 1080 aatatagtca attgaaacaa gagcaggaca aaagagcctc gtaaaaggta ttgcaacttg 1140 gtaatacctt tttgaggtgc tttttgatat gagcccatgt tttctcaata ggattgtact 1200 caggtgagta gggaggaaga ggtaaaagtt tacgcctaaa ctcttcacac aagagttcta 1260 gcttccccat tctatggaat cttgcattat ccataataat aaccgatggt gtggttaatg 1320 ttggtaagag aaacttctga aaccaagctt caaaaaagtc gctcgtcatc gtctcttcgt 1380 aagtcattgg agcgattaac tcaccattca tttgttagac ctgcaaccaa agaaatcctc 1440 tgatatcttc ttccagatac tttgcctctt attaactgac tttttaatga gcgaccatat 1500 tctcgataaa aataagtatc gattcctgtt tcatcaatct aaacaggtgc taggtgcttt 1560 aaactattaa aattcttaag aaataaggct actttttctg ggtcttgttc atagtaggtg 1620 tggttctttt ttcgagtgta gcccatagct ttgagcgcat agtggatggt agttggatga 1680 cagccaaatt cgaagctatt tcagtcaaat aagcatctgg attgtcagta agatagtttt 1740 taagtctatc tctatcaact tttcttggtt ttgttccttt tacttggtgg tttagctctc 1800 ctgttttctc ttttagcttt aaccagccat aaatggtatt acgtgagatt tggaaaacgt 1860 gtgatgcttc tgttatacta cctgttcgct cacaataaga gagaactttt ttacgaaaat 1920 ctattgaata tgccataaga agattatacc tcattgtgta ctatagtaga ttgaaactag 1980 aatagtacac atctgcttct aaaacattgt tagaaatcga tttgactgtc ccgatcgatt 2040 tgtcatgttc ttatttcatt ttactatatt tttgttttgc gggaagtcta ctaagatact 2100 taaagatgca gatagtgaaa aaaaaggtgt agacattacc gtaaaaaagt gatataatca 2160 taagatgttc aatgtatagg tgttaatcat gagtagacgt tttaaaaaat cacgttcaca 2220 gaaagtgaag cgaagtgtta atatagtttt gttgactatt tatttattgt tagtttgttt 2280 tttattgttc ttaatcttta agtacaatat ccttgctttt agatatctta atctagtggt 2340 aactgcgtta gtcctactag ttgccttggt agggctactc ttgattatct ataaaaaagc 2400 tgaaaaattt actatttttc tgttggtgtt ctctatcctt gtcagctcag tgtcgctctt 2460 tgcagtacag cagtttgttg gactgaccaa tcgtttaaat gcgacttcta attactcaga 2520 atattcgctc agtgtcgctc ttttagcaga tagtgagatc gaaaatgtta cgcaactgac 2580 gagtgtgaca gcaccgactg ggactgataa tgaaaatatt caaaaactac tagctgatat 2640 caagtcaagt cagaataccg atttgacggt cgaccagagt tcgtcttact tggttgctta 2700 caagagtttg attgcagggg agactaaggc cattgtccta aatagtgtct ttgaaaatat 2760 catcgagtta gagtatccag actacgcatc gaagataaag aagatttata ccaagggatt 2820 cactaaaaaa gtagaagctc ctaagacgtc taagaatcag tctttcaata tctatgttag 2880 tggaattgac acctatggac ctattagttc ggtgtcgcga tcagatgtca atatcctgat 2940 gactgtcaat cgtgatacca agaaaatcct cttgaccaca acgtcacgtg atgcctatgt 3000 accaatcgca gatggtggaa ataatcaaaa agataaatta acccatgcgg gcatttatgg 3060 agttgattcg tccattcaca ccttagaaaa cctctatgga gtggatatca attactatgt 3120 gctattgaac ttcacttctt tcttgaaaat gattgactta ttgggagggg tagatgttca 3180 taatgatcaa gagttttcag ctctacatgg gaagttccat ttcccagtag ggaatgtcca 3240 tctagactct gagcaggctc taggttttgt acgtgaacgc tactcactag ccgatggaga 3300 ccgtgaccgt ggtcgcaacc aacaaaaggt gattgtggct atccttcaaa aattaacgtc 3360 aaccgaagta ctgaaaaatt atagtacgat cattaatagc ttgcaagatt ctatccaaac 3420 aaatatgccg attgagacta tgatagattt agtgaatact cagttggaaa gtggaggtaa 3480 ttataaagta aattctcaag atttaaaagg gacaggtcgg atggatcttc cttcttatgc 3540 aatgccagac agtaacctct atatgatgga aatagatgat agtagtttag ctgtagttaa 3600 agcagctata caggatgtga tggagggtag atgaaatgat agacatccat tcgcatatcg 3660 tttttgatgt agatgacggt cccaagtcaa gagaggaaag caaggctctc ttggcagaat 3720 cctacaggca gggggtgcga accattgtct ctacctctca ccgtcgcaag ggtatgtttg 3780 aaactccgga agagaagata gcagaaagct ttcttcaggt tcgggaaatt gcaaaagaag 3840 tagcagatga tttagtcatt gcttacgggg ctgaaattta ctacacacca gatgttctgg 3900 ataagctggg aaaaaagcgg attccgaccc tcaatgatag tcgttatgcc ttgatagagt 3960 ttagtatgaa cactccttat cgcgatattc atagcgcctt gagcaagatc ttgatgttgg 4020 gaattactcc agtcattgcc cacattgagc gctatgatgc tcttggaaat aatgaaaaac 4080 gcgttcgaga actgattgat atgggctgtt acacgcaagt aaatagttca catgtcctca 4140 aaccaaaact ttttggcgaa cgttataaat tcatgaaaaa aagagctcag tattttttag 4200 agcagacttt ggttcatgtc attgcaagtg acatgcacaa tctagacggc agacctcctc 4260 atatggcaga agcatatgac tttgttaccc aaaaatacgg agaagcgaag gctcaggaac 4320 tttttataga caatcctcga aaaattataa tggatcaact aatttaggag aaatgatgaa 4380 agaacaaaac acgatagaaa tcgatgtatt tcaattattt aaaaccttgt ggaaacgcaa 4440 gctaatgatt ttattagtgg cacttgtgac aggtgcgggg gcttttgcat atagcacttt 4500 tattgttaag ccagaatata cgagtaccac gcgaatttac gtagtgaatc gcaatcaagg 4560 agacaagtcg gggctgacaa atcaggattt gcaggcagga tcttatctgg taaaagacta 4620 ccgtgagatt atcctttcgc aggatgcatt ggaaaaagta gcgacaaatt tgaagttgga 4680 catgccagca aaaacgttag ctagcaaagt tcaagtgact gtaccaactg acactcgtat 4740 cgtctcaatc tctgtcaagg ataaacagcc agaggaagcc agtcgtatcg ctaattctct 4800 acgagaagtt gctgtagaaa agatcgtcgc tgtaacgcga gtatctgatg taacgacact 4860 tgaagaagcg cgaccagcta cgactccttc ttctccaaat gttcgacgca attccttgtt 4920 tggttttctt ggaggagcag ttgtaacagt aattgctgtt cttttgattg agttgctcga 4980 cacccgtgtg aaacgtcctg aagatgttga agatgtactg caaattccac ttttagggct 5040 cgttccagat ttggacaaaa tgaaatagga ggaagttatg ccaacattag aaatctcaca 5100 ggcaaaattg gattttgtaa aaaaggcaga ggaatattat aactctttgt gcatgaacct 5160 acagttaagt ggaggtggtt tgaaagtatt ttctatcact tctgtgaaac taggagaagg 5220 aaaatcaacg acttccacca atatcgcttg ggcttttgcg cgtgcaggtt acaaaacgct 5280 gctgattgat ggagatattc gcaattctgt tatgttaggt gtctttaaag caagggataa 5340 gattacaggc ctgacagaat ttttatcagg aactacagac ctatcacaag ggctttgtga 5400 taccaatatc gaaaatctct ttgtaattca ggctggctct gtgtcaccga atccgacagc 5460 tcttcttcaa agtaagaatt tcactacaat gcttgaaacc ttgcgtaaat attttgacta 5520 catcattgta gatactgctc ctgtcggtgt cgtgattgat gcggctatta ttacgcgaaa 5580 atgcgatgct tctattttag tgacggaggc aggtgaaata aatcgacggg atattcaaaa 5640 agcaaaagaa cagttggaac acacagggaa gccgtttttg ggagttgtgt tgaataaatt 5700 cgatacttca gtaaacaaat acggttctta tggaaattat ggagattacg ggaaaaataa 5760 aaaatagatt gagggataga gatgaatgga aaagtagtaa attcctcatt ggccataatc 5820 catagttttc ttgttatttt attgacttat ctacttagtg ctgtgagaga agcggagatt 5880 gcttcagcaa cagctattgc actttatatc ctccattatt ttgtctttta tatcagtgat 5940 tatggacagg atttctttaa aaggggatat ttgattgaac ttgtccagac attgaaatat 6000 atcctattct ttgcactagc gattagtatt tctaattttt tcttagagga tcgatttagt 6060 atttccagac gaggcatgat ttacttcctc acattacatg ctctcttagt ctatgtgcta 6120 aacctattta tcaagtggta ttggaagcgg gcttatccca actttaaagg aagtaagaag 6180 attctcctac ttacagcaac ttctcgtgtc gaaaaggtac tggatagatt aatagaatca 6240 aatgaggttg ttggggagtt ggtagccgtc agtgtcttag ataaaccaga ttttcagcat 6300 gattgtttaa aggtagtagc agagggggag atagtaaact ttgcgactca tgaggtggtc 6360 gatgaagtct ttatcaatct tccaagtgaa aaatacaata ttggagagct tgtctctcag 6420 tttgaaacga tgggaattga tgtaacagtc aatctaaatg cttttgatcg tagtttggca 6480 cgtaacaagc aaattcgtga gatggcagga ttaaacgttg tgattttttc tacaacattt 6540 tataagacta gccacgtgat tgctaagcgg attattgata tcgtgggtgc attggtaggg 6600 ctgatactat gtggtctagt cagtgttgta ctggtccctt tgattcgaaa ggatgggggc 6660 tctgctattt ttgctcagac gcgtattgga aaaaatggtc gccacttcac tttttacaag 6720 ttccgctcca tgtgtgtaga tgctgaggac aaaaaaagag aactcatgga acaaaatacc 6780 atgcagggtg gaatgtttaa ggtggatgat gacccacgta tcacgaaagt tggtcgtttt 6840 atacggaaga ctagcttgga cgagctgcca cagttttata atgttctaaa gggagatatg 6900 agtttggttg gtacacgacc accaacagtg gacgagtata aacactatac tccagaacaa 6960 aaacgtcgtc taagttttaa acctggtata acaggtttat ggcaggttag tggacgaagt 7020 gagattaaga atttcgatga agttgtcaag ttagatgtag cttatataga tgattggaca 7080 atctggaaag atattgaaat cttattgaag acagttaaag ttgtattgat gaaggatgga 7140 gcgaagtaaa ggaatgaaaa ataaaaaaaa agtatgtttt tgtgcttcgt cagggggaca 7200 ttatgagcaa ctaatgaagc ttgaaccgat tatgagacaa caagacagct atttaatcac 7260 agaatatact gattataaca aaggagagtc tgagaagaaa gatataaaca aggtgtttta 7320 tcttttgcaa attaatcgtt tggaattttt ttggatcgtt aaattgattt ggatttcctt 7380 gaaatcactt tatatactgt taagaatacg cccaaaagta gttatctgta caggtgttct 7440 tgcaatgata ccgttttgtt tgctttcaaa aatgtttggg gctaaattaa tttatattga 7500 atcttttgca aaagtgacca ctcctacttt aacaggtaga atactatacc gttacgcaga 7560 tagattctat gtgcaatggg agagtatgct agatatctac ccaaatgctg tttataaagg 7620 ggggctttat taggtgattt ttataactgt agggactcaa aaacaccctt ttaatcgctt 7680 gttaaaaaaa atagatcaac ttattgaatt agaagtgata aaggaagagg tgtttgctca 7740 gattggagct tctgattata aacctaaata cttttcttat aattcatttt tgagttcaat 7800 tgatatgaat gagaaggtga gagaagctag tatggtaatt atacatggtg ggactgctag 7860 tattgttaaa gctttgaaat taagaaaaaa aattatagcg gttccacgat tagagcagtt 7920 tggagaacat gtggataatc accaattaca aatcatcaca gttcttggtg aggaaggtta 7980 tattttgcca tgctttgata tagagcagtt aggaactgtt tatcaaaaag ctcagacttt 8040 tacaacaaag ccatatattt ctaatagtta tgcactttta gaagatatac gacaatacat 8100 agatagtctt tgaaaggaaa tttagatgac aaaagttttg caaattgggc ctagtataaa 8160 tttatctaaa ggtggtatga gcgctgttat tagagatttg acatatagcc cgttattgtc 8220 aggtgatttt gatataactg cttatcaatc ttttattgat ggctctcttg taacacggtt 8280 aacctattct agttatgctc ttcttaaatt tgtagttcat tctggtaatt atgacatata 8340 ccatattcac actgctacaa gagggagttg ttggagaaaa ttactgtatt tgaaattact 8400 taaaagtaaa aataaaaaag ctattttgca tattcatgga gcagaatttc aaatatttta 8460 tgactcactt cctgagtata aaaaaaataa agttagagaa atgttagaat tatctgatta 8520 tgtgattgta ctttcccaaa cttggtatga ttttttttca aatattaata taaatgcaaa 8580 aattgtaata gttgaaaatg gtgtagacac ttctttttat gtagaaaaaa agaaaagtat 8640 aacaagcaac aactttcttt ttttaggaag gatgggcaaa agaaaaggag cctatgattt 8700 aatagatgcc atgaatcaag cagtggctat aaatcctaat ttgcatttga caatggctgg 8760 agatggagaa cttgaagaca tacgtcaaaa gatatcaaat ctgaatttga ctgatcatat 8820 tacaatatat gattgggtta atcagagaga taaaaaaata ctatttcaag ctaatcagac 8880 tttgatattg ccttcttata atgaggggct cccgatggca atattggaag ctatggcttc 8940 tggattagca atcatatcaa cgcctgtagg tggcatacct gaaattatac acgaggataa 9000 tggctggtta attcaaccgg gtgatatttc tcagttatct aatattattt tagaagcaag 9060 ttacaatccc gatgttgtaa gtttaatggg gagcaataat cataagttgg ttgaagagaa 9120 gtatagtttt catagtatgc atggtaaaat taaaaaaatt tataatactc tattagaaac 9180 gaaaaaataa tgactaaaaa atctattact agaaatttta ttttcaatac aattctaact 9240 atgtccagtt ttatttttcc actcatcagt ttcccatatg tttcaagggt tctgatggca 9300 gatgggttgg gacgagtaac gttcgcttct tcaattattg attatgccct aacatttgca 9360 atgttaggga tgccattata tggtgttaaa gtctgtgcag gatatattaa aaataaggag 9420 aagctaagtc agactgtcag agaattgtta gtcattaatt tattagtagg atttcttgtg 9480 atgcttcttt tagcaactat ggtaataata attcctcgtt ttagacagga atggcagctt 9540 attattatca cgtcatctac aattcctctc aatattatag gaatagagtg gttatacaaa 9600 gcattggaag actattcgta tatttcaatt agaacattga cttttaaaat attaggtttc 9660 cttttgatgt ttttagtcgt ccgaacaaaa gatgactata tggtatatgc ggcaattaca 9720 gttttagcta gtcatggttc ttttattttg aattttttta gatctagaac tttcctacta 9780 gaaaatatct ctcaaagatt gaatttaaag caacatataa agccgttatt aattttattt 9840 tttttatctg tatcatggac tatttataag aatacagatg tcgttatgat gggatttcta 9900 actagtgata cagaaattgg ttactattca acagcattaa aaattcgttc tatagtgctc 9960 agtgtagtaa cttctttagg gacagttgta ctacctcgtt tagtcaaata ttataaagaa 10020 ggaaagtata atgaagcaaa gaaaatacta aacaaaagtt cttcatttat tatgctaagt 10080 tctttatatt ttattggcta tattgtaatt aatgccagag aaattattct ttttattgcg 10140 ggtaggaatt acttaggggc tatcccgaca cttcaagtat ctatttttag tgcaatattt 10200 gttggctact ctattatgta tggaaccaat atcctagtat ctataggtaa agaaaatgta 10260 accattcagg caagtattat tggtgttgtt ttaaatattt gtttgaattt tattatgata 10320 cccaaatttg ctgcactagg ggcaggtatt gcaacttcta taggagaagc tgttatggta 10380 ttatatgaaa taatatactt gggaaaggat ggttggagct attttgaaag attaaatatt 10440 ttaaagatta ttgtagtatt tatatttagt acgtttatgt tatatattat gaaagatttt 10500 tttgttggct atcctttatt tatttatatt gtaatttcag gggttattta tagtattata 10560 tatatatttg gtcttatgat actaagagaa aatttgcttt caagttggaa aatatcaata 10620 ctaaatcggt ttaatattat taaagaatga ggagaatatt atatgattcc taaaaaaatc 10680 cactatattt ggttcggtgg aagtgagaaa ccagatgttg tcttaaaatg tattaattct 10740 tggaaaaaat atatgccaga ctatgagatt gttgaatgga atgaggataa ttttgattta 10800 tcagattcac aatttgcgaa gtctgcatat gaatctagga aatgggcatt tgcatcggat 10860 tatgctcgtt ttaaaatttt atctaagtat ggtgggatct attttgatac ggatgttgag 10920 ttgttaaaaa caatatcaga tgatatatta gctcattcat cttttacagg ttttgaatat 10980 attggtgaag taaatccagg acttgtatat gcttgtatgc cagatgataa gatagcaaaa 11040 tatatggtgc aatattatga gcaagcaagt tttgatatca atcatttggt aactgtcaat 11100 acaattatta cagattatct attaaaaaat aactttcaaa aaaataatca gttccaaata 11160 attgatggat tagcaattta tccagatgat tacttttgtg gttatgatca ggaggtcaag 11220 gaggttaggc ttacggaacg gacgattagt attcatcatt atagtgctac ttggaaaaca 11280 agaactttaa aaagaaaagt acagatgatt gttaaaacaa ttataggagc tgagaattat 11340 aggaaattat tatattgtaa gaggaaaata accaatgccg tatctaaata atgtaccgca 11400 aaataaattt tctataagat tatttgatat tgctatagtt ttattgactt taaagatgtt 11460 agtttcttcg attccagttt ttgactttgt gtttcctcaa aaatttcaaa atatccttgt 11520 tattttaggt tatatattga tttttttaca tatttttgag aaaagaaagt acacattaca 11580 atttataatt agtataattc taattactac attactgctt tatactagta tacaaatgca 11640 aaattatgtt tactttacga gttggtttat gttgattggt acgattcatt atgatttaag 11700 aagagtaata aaaattatat ttattgtatc attaagtatt atgttcatat caatttttat 11760 atcacttctt atgtatataa ttgattataa acgagaaatt cttattaata tccgaagaaa 11820 cgaaactgtc agagcattta catttggttt tatacatccc aataaattta ctattgtact 11880 atctaactta tgtcttatgt ttatttggtt aatcaaagat cgtttgaaat attatcatgt 11940 aactttttgt ctttttattc agttattctt ttattttttc acgcagacta gaacagctct 12000 actagtatct atagtaattt ttgctctttt atatatttat atgtttgttg aaaatcttga 12060 acttagatgg ataggatact cattcttttg tatttctact tttttaggag ttttggcatt 12120 tcaattttat ccttctaata ataagttttc aatttttatt gataatatcc tgactggacg 12180 tattaaatta gctgcatacg caagaacctt ttttggttat acattctggg gtcaatatgt 12240 tgataaagaa attgtttggg atcctatttg gggattaact agtttcactt ttgattcgtt 12300 ttattccttc ttgatgagta atgctggcat catatggcta cttatcttat cagtcttatt 12360 tgtaaaacta caaaaatatt tagacaataa aagtttgatt ttattattag cttggtctat 12420 gtatgcggta acagaaactg atttaatatt tccaagttat ggattccagt tcttattttt 12480 aagtatactt tttactaata ctagtacatg ttctacaata atgttaaaga ataattaatt 12540 gaaggaatct atatattttc taatttgtag aatgataggc aaatatatga ggagggaaga 12600 aaaagtatga aaatagcagt aacaggtacg ggatatgttg gcctatccat tgcggtttta 12660 ttggctcagc atcatcaagt aatagcggtg gacattattc ctgagaaggt cgagttaatt 12720 aatcaaagaa agtcacctat tcaagatgac tacatagaga aatatctggc agaaaaggat 12780 ttaaatttag tggctacatt ggatgcaaaa gaagcatata aagatgcgga ttttgttgtg 12840 attgcagctc caactaacta tgatccaaag aagaacttct ttgacacttc tgctgtagag 12900 tctgtcattg aaacggtgct taaatataat ccagatgcta tcatggtcat taaaagtacg 12960 gttccagttg gttatacaga gtcagctcga aagaaatttc agactgaaaa tatcttattt 13020 agtcctgaat ttttgcgtga gtcaaaagca ctttacgata acttatatcc cagccgtatt 13080 attttaggga cagataaaaa taatgaacgc ttggtaagtg ttgctgagac gtttgcggga 13140 ttgctccaag aaggcgcttt aaaagaagat attgatacat tgtacatggg ctttactgaa 13200 gctgaggcgg tcaagctttt tgcaaatact tacctagctt tgcgtgtttc ttattttaat 13260 gagctggata cttattctga gatgaagggg ctagatactc aagctattat tgatggagtt 13320 ggtttggatc cacgaatcgg ctctcactat aacaatcctt ccttcgggta tggtggttac 13380 tgtctcccta aagataccaa gcaacttctt gccaactatg aagatgtacc agaagaactt 13440 ataggagcta tagtacggag caattcgaca cgtaaagact ttattgccga tcaggttctt 13500 aagatggtag attcttatga ttattcagcc cataatgttt ttaatgagag agtagaaaaa 13560 gatattatta ttggtatcta tagattgacc atgaagagta atagcgataa ttttcgtcaa 13620 agttctattc aaggtattat gaaacgtata aaagctaagg gagtaagagt agttatttat 13680 gaaccaactt tagaaagtgg gagtacattt tttggaagtt ccattatcaa tgatttagag 13740 gaattcaaac gactgagtaa tgccattgtt gctaatcgct atgataactc attagaagat 13800 gtcaaggaaa aagtctatac acgtgatatt tttgaaagag attgatttag tataataaaa 13860 atgtaaaaaa ttaattgtta gaagcggtct atactgagaa gcaatgggac gcttagcaga 13920 ttatacatat tacgatatgc atgttgtgat tgaacgagcg ctcgaagtta tagaaaaaga 13980 gtttgaaaat gacaaaaatt agaatcaatt ggatagattt tggaaaaggt tctcaatatt 14040 tttagtttta gtagagcgtc tatatcctcc attccccaat ttgtagtatg attctaattc 14100 tgatgttgaa agtgggaatt agctctactt tacttcatat tgttatcgga attgttttgg 14160 gctggcattt atccatccta gcaacctata tattgaaaaa aattccattt ttgaatattg 14220 ttttattacc acagaagtat attaaattaa aataaattat tttggctctt tgtcagctaa 14280 catctggaga ggacaatcac cgtcttctcc tttttggtct tttcagaata tactaaacta 14340 acccaaaaat tctgaaaatt ctgttgacat ctttttgaaa agagtctata atggagagaa 14400 agttttaaag gagaaaatga tgaaaagttc aaaactattt gcccttgcgg gcgtgacatt 14460 attggcggcg actactttag ctgcatgctc tggatcaggt tcaagcgcta aaggtgagaa 14520 gacattctca tacatttatg agacagaccc tgataacctc aactatttga caactgctaa 14580 ggctgcgaca gcaaatatta ccagtaacgt ggttgatggt ttgctagaaa atgatcgcta 14640 cgggaacttt gtgccgtcta tggctgagga ttggtctgta tccaaggatg gattgactta 14700 cacttatact atccgtaagg atgcaaaatg 14730 // |
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