 |
|
EBI DbfetchID AJ132472; SV 1; linear; genomic DNA; STD; PRO; 11181 BP. XX AC AJ132472; XX DT 02-AUG-1999 (Rel. 60, Created) DT 15-APR-2005 (Rel. 83, Last updated, Version 3) XX DE Ruminococcus flavefaciens xylan utilization operon XX KW ABC-type Sugar Transporter; AraC-type Regulator; KW Family 11 Xylanase/Family 16 Beta (1,3-1,4)Glucanase; KW Family 3 Glycoside Hydrolase; ORF; xsi gene; xyla gene; xylose isomerase; KW xynD gene. XX OS Ruminococcus flavefaciens OC Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; OC Ruminococcus. XX RN [1] RP 1-11181 RA Flint H.J.; RT ; RL Submitted (01-FEB-1999) to the EMBL/GenBank/DDBJ databases. RL Flint H.J., Division of Microbial and Intestinal Biology, Rowett Research RL Institute, Greenburn Road, Bucksburn, Aberdeen, AB21 9SB, UNITED KINGDOM. XX RN [2] RA Aurilia V., Martin J.C., Munro C.A., Mercer D.K., Flint H.J.; RT "Organisation and strain distribution of genes responsible for the RT utilization of xylans by the rumen cellulolytic bacterium Ruminococcus RT flavefaciens 17"; RL Unpublished. XX FH Key Location/Qualifiers FH FT source 1..11181 FT /organism="Ruminococcus flavefaciens" FT /strain="17" FT /mol_type="genomic DNA" FT /country="United Kingdom" FT /db_xref="taxon:1265" FT CDS <1..551 FT /codon_start=3 FT /transl_table=11 FT /product="Putative AraC-type Regulator" FT /note="ORF1" FT /db_xref="GOA:Q9S311" FT /db_xref="InterPro:IPR018062" FT /db_xref="UniProtKB/TrEMBL:Q9S311" FT /protein_id="CAB51933.1" FT /translation="PVQMSLEFLSYCVKSIAYEKYSDNPCSAETSDLFMKLMFIKIRER FT ALNKVAGRRSTQFELISTVRNKIYSRPYEQRNVDSTAHEVRMSRSAFQHAYKKHFGMTF FT IEDLVRSRVSYAKMLLSTTNMNINDISTSSGYHSYVHFARQFKEQTGVTPSEYRKKAQS FT VTVRRSPEMSRGALRCNDV" FT mat_peptide <1..548 FT /product="Putative AraC-type Regulator" FT CDS 592..3000 FT /transl_table=11 FT /gene="xynD" FT /product="Family 11 Xylanase /Family 16 Beta (1,3-1,4) FT Glucanase" FT /note="ORF2" FT /db_xref="GOA:Q9S310" FT /db_xref="HSSP:1AJK" FT /db_xref="InterPro:IPR013320" FT /db_xref="UniProtKB/TrEMBL:Q9S310" FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="CAB51934.1" FT /translation="MKKSIFKRYAAAVGLMASVLMFTAVPTTSNAADDQKTGKVGGFDW FT EMWNQNYTGTVSMNPGAGSFTCSWSGIENFLARMGKNYDDQKKNYKAFGDIVLTYDVEY FT TPRGNSYMCIYGWTRNPLMEYYIVEGWGDWEPPGNDGVDNFGTTTIDGKTYKIRKSMRY FT NQPSIEGTKTFPQYWSVRTTSGSRNNTTNYMKDQVSVTKHFDAWSKAGLDMSGTLYEVS FT LNIEGYRSNGSANVKSISFDGGIDIPDPEPIKPDENGYYLKENFESGEGNWSGRGSAKV FT KSSSGYDGTKGIFVSGREDTWNGASINLDELTFKAGETYSLGTAVMQDFESSVDFKLTL FT QYTDADGKENYDEVKTVTAAKGQWVDLSNSSYTIPSGATGLVLYVEVPESKTDFYMDGA FT YAGVKGTKPLISISSQSVDPPVTEPTNPTNPTGPSVTKWGDANCDGGVDLSDAIFIMQF FT LANPNKYGLTGTETNHMTNQGKVNGDVCEHGSGLTGDDAVSIQKYLIRAISELPESYLE FT GHDPSKTTTTTTRITTTTTTTTTTTTSKTTTTTTTTSPAMHGGYRDLGTPMNTSATMIS FT DFRTGKAGDFFASDGWTNGKPFDCWWYKRNAVINDGCLQLSIDQKWTNDKNPDWDPRYS FT GGEFRTNNFYHYGYYECSMQAMKNDGVVSSFFTYTGPSDDNPWDEIDIEILGKNTTQVQ FT FNYYTNGQGKHEKLYDLGFDSSEAYHTYGFDWQPNYIAWYVDGREVYRATQDIPKTPGK FT IMMNAWPGLTVDDWLKAFNGRTPLTAHYQWVTYNKNGVQHSSQGQNPWG" FT mat_peptide 595..2997 FT /gene="xynD" FT /product="Family 11 Xylanase /Family 16 Beta (1,3-1,4) FT Glucanase" FT /experiment="experimental evidence, no additional details FT recorded" FT stem_loop 3047..3080 FT /function="potential rho-independent transcription FT terminator" FT stem_loop 3081..3117 FT /function="potential rho-independent transcription FT terminator" FT CDS complement(3139..3987) FT /transl_table=11 FT /product="Putative AraC-type Regulator" FT /note="ORF3" FT /db_xref="GOA:Q9S309" FT /db_xref="HSSP:1BL0" FT /db_xref="InterPro:IPR018062" FT /db_xref="UniProtKB/TrEMBL:Q9S309" FT /protein_id="CAB51935.1" FT /translation="MIKNLSGDYETVEYENQRFVMLYDNDEIEEYPTHWHNAVEVIIPL FT HNGFTVTAGGVDYHLNEKEIIIIPPGELHSMPAQEGRRIIFQCDNSIISDVPALEAIVP FT VFSEAFHITPTISKELYILSRKSILDIYSEYYSKSSLSDVRIYLCLIKMLTSVREYQLT FT QAADAFSGELGGRDDTRKFSMVMKYINQNYMYEIPLEKIASIAGYSKYHFSRIFKKYNN FT VSYIQYINSKRIKAAERLLIDPNLSVTEVAMRAGFASLTTFNRAFKKAKNCTPTEFQDI FT V" FT mat_peptide 3142..3984 FT /product="Putative AraC-type Regulator" FT CDS 4211..5068 FT /transl_table=11 FT /product="hypothetical protein" FT /note="ORF4" FT /db_xref="UniProtKB/TrEMBL:Q9S308" FT /protein_id="CAB51936.1" FT /translation="MSVKCYESDYKNYGKCLCLDNGKIKLIVTIDVGPRIVFFGFKDGD FT NVLFEDVDRNFYEINNGYGVWYAYGGHRIWSAPEVMPETYLPDNSKVEAIFDDGVLTLT FT PAKTKFDKQFELVIAMGDDCSVTVENKITNCSDKAAEFAPWSVTGLAAGGVELIPLCRD FT DNGFLPNRTVALWSYSDINDHRFTLADGYAILRQDSKEKKAFKAGFNVTGKQVIYIKGH FT NILRLCFDGYEPVRYPDFCCNYETYTNDLFLECEILGELKSYLPGETVFIQGKMGTFNY FT RVGC" FT CDS 5166..7238 FT /transl_table=11 FT /gene="xylA" FT /product="Family 3 Glycoside Hydrolase" FT /note="ORF5" FT /db_xref="GOA:Q9S307" FT /db_xref="InterPro:IPR001764" FT /db_xref="UniProtKB/TrEMBL:Q9S307" FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="CAB51937.1" FT /translation="MLVEKYLDEALSDLERAEDITDRLSTEEKAEQQKYDAPAEERLGK FT DAYNWWSEGLHGVARAGTATMFPQTIGMAAMFDDEAVHRAGETTSREARAKYNEYSAHD FT DRDIYKGLTLWSPNVNIFRDPRWGRGQETYGEDPYLTSCLGVAYAKGLQGDGKVLRTAA FT CAKHFAVHSGPEATRHEFDAKANMKDMTETYIAAFEALVKDAKVESVMGAYNRVNGEPA FT CASDFVMNKLEEWGFDGHFVSDCWAIRDFHTNHGVTKTAPESAALALKKGCDLNCGNTY FT LHLLAAFNEGLINEEDLRRSCIKLMRTRVRLGMFDKSTEYDGLDYDIVACDEHKEFSLR FT CSERSMVLLKNNGILPLDGSKYKTIGVIGPNADSVPALEGNYNGKADEYITFLSGIREA FT HDGRVLYTEGSHLYKDRCMGLALPDDRLSEAEIITRTLRCSGSLCWLDATIEGEEGDTG FT NEFSSGDKNDLRLPESQRKLVKTVMAKGKPVIIVTAAGSAINVEADCDALIQAWYPGQL FT GGRALANILFGKVSPSGKLPVTFYEDASKLPDFSDYSMKNRTYRYSEGNILFPFGYGLT FT YSETECSELSFENGVATVKVTNTGSRFTEDVVQIYIKGYSENAVPNHSLCGFKRVALDA FT GESRIVQITLPERAFMAVNEKGEWIKEGSEFTLYAGTSQPDELSKKLTGKECTTL" FT CDS 7263..8579 FT /transl_table=11 FT /gene="xsi" FT /product="Xylose Isomerase" FT /note="ORF6" FT /db_xref="GOA:Q9S306" FT /db_xref="HSSP:1A0C" FT /db_xref="InterPro:IPR018115" FT /db_xref="UniProtKB/Swiss-Prot:Q9S306" FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="CAB51938.1" FT /translation="MEFFSNIGKIQYQGPKSTDPLSFKYYNPEEVINGKTMREHLKFAL FT SWWHTMGGDGTDMFGCGTTDKTWGQSDPAARAKAKVDAAFEIMDKLSIDYYCFHDRDLS FT PEYGSLKATNDQLDIVTDYIKEKQGDKFKCLWGTAKCFDHPRFMHGAGTSPSADVFAFS FT AAQIKKALESTVKLGGNGYVFWGGREGYETLLNTNMGLELDNMARLMKMAVEYGRSIGF FT KGDFYIEPKPKEPTKHQYDFDTATVLGFLRKYGLDKDFKMNIEANHATLAQHTFQHELR FT VARDNGVFGSIDANQGDVLLGWDTDQFPTNIYDTTMCMYEVIKAGGFTNGGLNFDAKAR FT RGSFTPEDIFYSYIAGMDAFALGFRAALKLIEDGRIDKFVADRYASWNTGIGADIIAGK FT ADFASLEKYALEKGEVTASLSSGRQEMLESIVNNVLFSL" FT mat_peptide 7266..8576 FT /gene="xsi" FT /product="Xylose Isomerase" FT /experiment="experimental evidence, no additional details FT recorded" FT CDS 8627..10027 FT /transl_table=11 FT /product="hypothetical protein" FT /note="ORF7" FT /db_xref="GOA:Q9S305" FT /db_xref="InterPro:IPR006059" FT /db_xref="UniProtKB/TrEMBL:Q9S305" FT /protein_id="CAB51939.1" FT /translation="MKKALSVISAIALLASCVAATGCSKKDEGTNTDSTPSGGGEKKGK FT TVINLWTFTDEVPKMVKKYMEMNPDFAAQYEVKETIIPTTDGNYQPALDKALQAGGKDA FT PDFYCAEAAFVLKYTQGDMSSYAAPYEDLGIDVENEINASKIAPYSVDIGTNPATNKVV FT GLGYQATGGAFIYRRSVAKATFGTDDPSTVAEKIGAGSGSWDKFFDAAEELKGKGYAIV FT SGDGDIWHAVENSSDKGWMDGDKLFIDSKREEFLDLSKKLKDNNYHNDTEDWSEAWKAD FT MRGEGDKEVLGFFGPAWLINYTIAENCGGKKPGEGTYGDWAVCAPPIGFFWGGTWLIAN FT KDSEKKEAVGKIIDWITLDSSDTGLQYMWANGTLNGPGGTKDCVASNTVMEKSDGSLEF FT LGGQNMFDAFVPANEYANGKNLTQYDEKINSSWRGQVRQYTAGNKSRDAAIKDFKQEVA FT DNLGISVD" FT stem_loop 10036..10069 FT CDS 10094..11086 FT /transl_table=11 FT /product="Putative ABC-type Sugar Transporter" FT /note="ORF8" FT /db_xref="GOA:Q9S304" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9S304" FT /protein_id="CAB51940.1" FT /translation="MKTKLKGISYSKYGYLFSIPFIVAFLIFTLYPTIYTATLGFTDCK FT GVNGPENYHFLDKPFENFKSILENDTFRISLKNTILIWIMNFIPQISIALLLTAWFTSH FT SNEIRGKGFFKVVFYMPNIITAATVAILFHTLFNYPIGPVNDFLESTGLRESPYYFFTS FT KTACRIIVAFIQFWTWYGNTMIVLISGVLGISPDIYEAAEIDGANGVQTFFRITIPNLK FT TVLLYTLITSLVGGLNMFDIPFLFLNGGPDRATTTTSVFIYNQAFAGSYLYNKAAAASM FT IMWVIIALCSAVLFFVMRDKDQIKLEKEIKRAKKEAKLASKGGVNQWQW" XX SQ Sequence 11181 BP; 3208 A; 2415 C; 2714 G; 2843 T; 1 other; ctcccgtgca gatgtcgctg gagttcctaa gctactgcgt aaaatccatt gcttatgaaa 60 agtattcgga caatccctgc agcgcagaga cttccgacct ttttatgaag ctcatgttta 120 taaagatccg tgaaagagca cttaataaag tggctggcag gagaagcact cagtttgagc 180 ttatctccac tgtgcgcaac aagatataca gccgtcccta cgagcagcgc aatgtggaca 240 gcaccgctca tgaagtgcgg atgagccgct cggctttcca gcacgcttat aaaaagcatt 300 tcggaatgac ttttatagag gatcttgtcc gcagcagagt tagctatgca aaaatgcttc 360 tttccactac caatatgaat ataaatgaca tttccacaag cagcggttat cacagctatg 420 ttcactttgc aaggcaattc aaggaacaga cgggagttac gccgtctgaa taccgcaaaa 480 aggcacagag tgtaactgtg aggcggtcgc ccgaaatgag tcggggngcg ctgcgttgca 540 atgatgtata aataatacag tgaccacggt cacggaatga gagggctgat tatgaaaaag 600 agcatattca agcgttatgc tgctgctgtc ggtttaatgg cttcagttct tatgtttacc 660 gcagtaccga caacgtcaaa tgctgctgat gaccagaaaa caggtaaggt cggcggattt 720 gactgggaaa tgtggaacca gaactatacc ggtacagttt ctatgaatcc gggcgcaggt 780 tcatttacct gttcgtggag cggcattgag aacttccttg ctcgaatggg taagaattat 840 gacgaccaga agaagaacta taaggctttc ggtgacatcg tgcttacata tgatgttgag 900 tacactcccc gcggaaactc gtatatgtgt atttacggct ggacaagaaa tccccttatg 960 gaatactata tcgttgaagg ctggggcgac tgggagccac ccggaaatga cggcgtagac 1020 aatttcggta caacaactat cgacggaaaa acatataaga tacgcaagtc catgcgttac 1080 aatcagcctt ctatcgaggg aacaaagaca ttcccgcagt actggagcgt ccgcactaca 1140 agcggttcac gcaataatac tacaaactat atgaaggatc aggtctctgt taccaagcat 1200 tttgacgcat ggagcaaggc aggtctcgac atgagcggta cactttatga ggtatcactt 1260 aatatcgaag gctacagatc aaacggttct gccaatgtca agagcatatc ctttgacggc 1320 ggtattgata ttcccgatcc cgagccgata aagcctgacg agaacggcta ctatctcaag 1380 gaaaattttg agtccggcga aggaaactgg agcggacgcg gatctgcaaa ggtcaagtca 1440 agctcaggct atgacggaac gaagggcatc tttgtttcag gccgtgaaga tacatggaac 1500 ggcgcttcca taaacctcga tgaacttaca ttcaaggcag gagagactta cagcttaggt 1560 actgctgtta tgcaggactt cgagtcatct gttgacttca agcttactct tcagtataca 1620 gatgctgacg gcaaagagaa ttatgatgag gtaaagactg ttactgctgc aaagggacag 1680 tgggtagatc tttcaaattc ttcatatacg ataccttcgg gagcaacagg acttgttctc 1740 tatgttgagg tgcctgagag caagacagac ttctatatgg acggcgctta tgctggcgtt 1800 aagggcacaa agcctcttat ctccatttct tctcagtctg ttgatcctcc tgttacagag 1860 cctacaaatc ccacaaatcc taccggtcct tcggttacaa agtggggtga tgcaaactgt 1920 gacggcggtg tagacctcag tgatgctata tttatcatgc agtttcttgc aaatccgaat 1980 aagtatggtc ttacaggaac tgagacaaat catatgacca atcagggaaa ggtcaacgga 2040 gatgtctgcg agcatggttc gggacttacc ggagacgatg ctgtttccat ccagaagtac 2100 ctcatccgtg ccatcagcga gcttccagag tcttatctcg aaggccatga tccttcaaag 2160 acaacgacca ctacaacaag gatcactact acaactacaa ctaccacaac gactacaaca 2220 tcgaagacaa cgaccactac taccacaact tctcccgcaa tgcacggcgg ttacagagat 2280 cttggtactc ctatgaatac aagtgctaca atgatctcag atttccgtac aggcaaggca 2340 ggcgacttct ttgcatccga cggatggacc aacggcaagc ctttcgactg ctggtggtac 2400 aagcgtaatg ctgttatcaa tgacggctgt ctccagctga gcattgacca gaaatggaca 2460 aatgacaaga atcccgactg ggatccccgt tattccggcg gtgagttccg tacaaataat 2520 ttctatcact acggatacta cgagtgctca atgcaggcta tgaagaatga cggtgttgta 2580 tcatcgttct tcacctatac aggtccgtct gacgataacc cgtgggatga gatcgatatc 2640 gagatccttg gcaagaacac tacacaggtt cagttcaact attacacaaa cggtcaggga 2700 aagcatgaga agctgtacga cctcggcttt gattcttctg aggcttatca tacatacggc 2760 tttgactggc agccgaacta catcgcatgg tatgtagacg gcagggaagt ttatcgtgct 2820 actcaggata ttcccaagac ccccggaaag atcatgatga acgcatggcc cggacttaca 2880 gttgatgact ggctcaaggc attcaacgga agaactcctc ttacagctca ctatcagtgg 2940 gttacatata ataagaacgg tgttcagcac agcagtcagg gacagaaccc ctggggttga 3000 taaaacgcaa taattgaagc ttaggcaatt ttcttccatt atataataag cagggcagta 3060 caaatgtact gccctgcttg cataaaagcg gttgcacatc atgcagccgc ttttatgatt 3120 tatgtgtgat ctgagatctt atacaatgtc ttgaaactct gtgggagtgc agtttttggc 3180 ttttttgaag gcgcgattaa atgtggtcag actggcaaag ccggcacgca tagcgacctc 3240 ggtaacggaa agattgggat ctatgagaag cctttccgct gcttttatcc tcttgctgtt 3300 tatatattgt atataggaaa cattattgta cttcttgaag atacgtgaga agtggtattt 3360 gctgtagccg gcgatggatg ctatcttttc aagaggtatc tcgtacatat agttctggtt 3420 gatgtacttc attaccatgc tgaacttcct tgtatcgtcc ctgccgccaa gctcgccgga 3480 aaatgcgtcg gctgcctgag tgagctggta ctcgcgtaca gaagtgagca tttttataag 3540 acaaaggtat atccttacat ccgaaagaga agattttgag tagtactcgg aataaatatc 3600 gagtatgctc ttgcgcgaca ggatatagag ctccttgctt attgtagggg ttatgtggaa 3660 tgcctccgag aaaacgggga caatagcttc cagcgcggga acatcgctta ttatactgtt 3720 atcacactgg aagatgatcc tgcgtccttc ctgagccggc atggaatgaa gctctccggg 3780 agggatgatt attatttcct tttcatttaa atggtaatcg acaccgccgg cggtaacggt 3840 gaagccgttg tgcaggggta ttattacttc aacggcattg tgccagtgag taggatattc 3900 ttcaatttca tcgttgtcgt aaagcatgac aaatctttgg ttttcgtact caacggtttc 3960 atagtcaccg gatagatttt taatcatgat tagcctcctt aaccaaaaat tgttgtgaaa 4020 aatatgtcaa tattcataaa tcagcgtaat atctggatat attatacact attatcatag 4080 tatttgtaaa gtgggtttga agaatttgtg caatgttagc aattcttgaa taaacagacg 4140 caatttttga ttagtataaa ttgccgaagt agtatataat agcaatagag caaacgaaag 4200 gtgatgtgtg atgtctgtta aatgctatga gagcgactac aagaattatg ggaagtgtct 4260 ttgccttgat aacgggaaaa taaagctcat cgtcactata gatgtaggac cgagaattgt 4320 tttcttcgga ttcaaggacg gggacaacgt tctttttgag gatgttgaca gaaatttcta 4380 cgaaatcaat aacggatacg gtgtatggta tgcttacggc ggtcacagaa tatggtcagc 4440 tccggaggtc atgcctgaaa cttatcttcc cgataattca aaagtagaag ctatttttga 4500 cgacggtgtt cttacactca ccccggcaaa aacaaaattt gataagcagt tcgagctggt 4560 tattgcaatg ggcgatgatt gctcggtaac tgttgagaac aagatcacca actgctcgga 4620 taaagctgcg gagtttgcac cgtggtccgt tacgggactt gcggcaggag gagtggagct 4680 tattccgctt tgccgtgatg ataacggctt tttgcctaac agaacggtgg ctctgtggag 4740 ctactcggac ataaacgatc acaggtttac tcttgcagac ggctatgcta tcctcaggca 4800 ggattcgaag gagaagaaag cattcaaggc cggcttcaat gtaacaggaa aacaggtaat 4860 atacattaaa ggacacaata tattaagact gtgcttcgac ggatacgagc ccgttagata 4920 tcctgatttc tgctgcaatt atgaaaccta cacaaatgac ctttttcttg agtgcgagat 4980 actcggagag cttaaaagct acctcccagg cgagactgtt tttattcaag gaaaaatggg 5040 aactttcaac tacagagtgg gctgctgata aggtaataga tgaatttgta agcaaattat 5100 aatcaaattg taacaaaaaa ataattggat tgtaaataaa atatagtata atttaagaaa 5160 ggagaatgct tgtggagaag tatttggacg aagcattatc cgatcttgag agagccgagg 5220 acattacgga caggctttca acagaggaaa aagctgaaca gcagaagtat gatgctcccg 5280 cagaagaacg tctggggaaa gacgcttaca attggtggag cgagggctta catggtgttg 5340 caagagcagg aacagcaaca atgtttccgc agaccatcgg catggctgcc atgttcgatg 5400 atgaggctgt tcacagagca ggcgagacaa cttctagaga agcaagagcc aagtataacg 5460 agtattcagc tcacgatgat cgtgacatat ataaaggcct tacactctgg tcaccgaatg 5520 taaatatatt ccgtgatccg agatggggca gaggtcagga gacctacggt gaagaccctt 5580 atcttacatc atgtctcgga gttgcttatg caaagggact gcagggagac ggaaaagtcc 5640 tcagaactgc tgcctgcgca aagcatttcg ctgttcacag cggccccgaa gctacaagac 5700 atgagtttga tgccaaggca aatatgaagg atatgacaga gacctatatc gccgcctttg 5760 aggctcttgt aaaagatgcc aaggtcgaga gcgttatggg agcttacaac cgtgtaaacg 5820 gtgagcccgc ctgtgcaagc gattttgtta tgaataagct tgaggaatgg ggctttgacg 5880 gtcatttcgt ttcagactgc tgggcgataa gagacttcca tacaaaccac ggagttacca 5940 aaacggctcc cgagtccgca gcgcttgcac tcaaaaaggg ctgcgacctc aactgcggca 6000 atacatatct tcatcttctt gccgcattca atgaaggtct catcaacgag gaggatctca 6060 gacgttcctg catcaagctg atgagaacaa gagtaaggct gggaatgttc gacaagtcca 6120 ctgagtatga cggacttgat tacgacattg tagcctgcga tgagcacaag gaattctcgc 6180 tcagatgttc ggagcgttcc atggtgctcc tgaaaaataa cggtatcctg cctctcgacg 6240 gcagtaaata caagactatc ggtgttatag gcccaaatgc tgacagtgtt cccgcacttg 6300 agggaaacta caacggtaaa gcggatgagt acatcacgtt cctcagcggt atacgcgagg 6360 cacatgacgg aagagtgcta tacaccgaag gaagtcacct ttataaggac agatgcatgg 6420 gactggctct tcccgacgac agactctccg aagcggagat cattaccaga acactccgat 6480 gtagtggttc tttgtgttgg cttgatgcta ccatcgaggg cgaagaggga gacacaggaa 6540 atgaattctc ctcaggtgac aagaatgatc tcagacttcc tgagtctcag agaaagctcg 6600 ttaagacggt aatggctaaa ggtaagcccg tcatcatagt tactgcggca ggcagtgcaa 6660 taaatgttga agcagactgc gatgctctta tacaggcatg gtatccaggt cagcttggcg 6720 gcagagctct tgcgaatata cttttcggta aggtctctcc ttcaggtaag cttccggtaa 6780 cattctatga agatgcttca aagctgcccg atttctcgga ttacagcatg aagaaccgta 6840 cttacagata ttccgaggga aatatcttgt tccccttcgg ctacggactg acctactccg 6900 agacagagtg ttcggagctg tcctttgaga acggcgtagc tactgtaaag gtaactaata 6960 caggcagccg ctttacagag gacgtagttc agatctatat caaaggttat tcggagaacg 7020 cagttcctaa tcacagcctc tgcggcttca agagagtcgc gcttgacgca ggcgagagca 7080 ggatcgtaca gatcactctc cctgaaagag cctttatggc tgtcaatgaa aagggcgagt 7140 ggataaagga aggcagtgag ttcaccctct acgcaggcac ctctcagcca gacgaactca 7200 gcaaaaagct gacaggcaag gaatgcacaa ctctgtaaaa taaatatata atggaggata 7260 aaatggaatt tttcagcaat atcggtaaaa ttcagtatca gggaccaaaa agtactgatc 7320 ctctctcatt taagtactat aaccctgaag aagtcatcaa cggaaagaca atgcgcgagc 7380 atctgaagtt cgctctttca tggtggcaca caatgggcgg cgacggaaca gatatgttcg 7440 gctgcggcac aacagacaag acctggggac agtccgatcc cgctgcaaga gcaaaggcta 7500 aggttgacgc agcattcgag atcatggata agctctccat tgactactat tgtttccacg 7560 atcgcgatct ttctcccgag tatggcagcc tcaaggctac caacgatcag cttgacatag 7620 ttacagacta tatcaaggag aagcagggcg acaagttcaa gtgcctctgg ggtacagcaa 7680 agtgcttcga tcatccaaga ttcatgcacg gtgcaggtac atctccttct gctgatgtat 7740 tcgctttctc agctgctcag atcaagaagg ctctcgagtc aacagtaaag ctcggcggta 7800 acggttacgt tttctggggc ggacgtgaag gctatgagac acttcttaat acaaatatgg 7860 gactcgaact cgacaatatg gctcgtctta tgaagatggc tgttgagtat ggacgttcga 7920 tcggcttcaa gggcgacttc tatatcgagc ccaagcccaa ggagcccaca aagcatcagt 7980 acgatttcga tacagctact gttctgggat tcctcagaaa gtacggtctc gataaggatt 8040 tcaagatgaa tatcgaagct aaccacgcta cacttgctca gcatacattc cagcatgagc 8100 tccgtgttgc aagagacaat ggtgtgttcg gttctatcga cgcaaaccag ggcgacgttc 8160 ttcttggatg ggatacagac cagttcccca caaatatcta cgatacaaca atgtgtatgt 8220 atgaagttat caaggcaggc ggcttcacaa acggcggtct caacttcgac gctaaggcac 8280 gcagagggag cttcactccc gaggatatct tctacagcta tatcgcaggt atggatgcat 8340 ttgctctggg cttcagagct gctctcaagc ttatcgaaga cggacgtatc gacaagttcg 8400 ttgctgacag atacgcttca tggaataccg gtatcggtgc agacataatc gcaggtaagg 8460 cagatttcgc atctcttgaa aagtatgctc ttgaaaaggg cgaggttaca gcttcactct 8520 caagcggcag acaggaaatg ctggagtcta tcgtaaataa cgttcttttc agtctgtaaa 8580 ggctgattga aataatatca atttttataa ttggaggtca agaaaaatga aaaaagcatt 8640 atcggtcatc tcagcaatcg cacttctcgc ttcatgcgta gctgctacag gctgcagcaa 8700 gaaggatgaa ggcacaaaca ctgactcaac acccagcggc ggtggcgaga agaagggcaa 8760 gacagtaatc aatctctgga cattcactga cgaagttccg aagatggtta agaagtacat 8820 ggaaatgaac cctgacttcg ctgctcagta tgaggttaag gagacaatca ttcctacaac 8880 tgacggtaac tatcagcctg cacttgataa ggctcttcag gccggcggca aggatgctcc 8940 cgacttctac tgcgctgagg ctgcattcgt tctgaagtat acacagggcg atatgtcaag 9000 ctacgctgct ccttacgagg atctcggaat cgacgttgaa aatgagatca acgcttccaa 9060 gatcgctcct tactctgtag atatcggtac aaatcctgca actaacaagg ttgttggtct 9120 tggttaccag gctacaggtg gtgcatttat ctacagacgt tcagttgcta aggcaacatt 9180 cggcacagac gatccttcta cagtagcaga gaagatcggt gcaggttcag gcagctggga 9240 taagttcttc gatgctgctg aagagctcaa gggcaagggc tatgctatcg tttccggtga 9300 cggtgatatc tggcacgctg ttgagaacag ctctgacaag ggctggatgg acggcgacaa 9360 gctcttcatc gattccaaga gagaggaatt cctcgatctt tccaagaagc tcaaggacaa 9420 taactatcac aacgatacag aagactggtc tgaggcttgg aaggctgata tgagaggcga 9480 gggcgataag gaagttctcg gattcttcgg tcctgcatgg ctcatcaact acacaattgc 9540 tgagaactgc ggcggtaaga agcccggcga aggcacatac ggtgactggg cagtttgtgc 9600 acctcctatc ggattcttct ggggcggtac atggctcatt gctaacaagg acagcgagaa 9660 gaaggaagca gttggtaaga tcatcgactg gatcacactt gattcttctg acacaggtct 9720 tcagtatatg tgggctaacg gcacactcaa tggccctggc ggaacaaagg actgcgtagc 9780 ttctaacaca gttatggaga agtctgacgg atctctcgag ttcctcggcg gacagaatat 9840 gttcgatgca ttcgttcccg ctaacgagta tgcaaacggt aagaacctca ctcagtatga 9900 tgagaagatc aacagctcat ggcgtggaca ggttcgtcag tacacagctg gcaacaagtc 9960 aagagacgct gctatcaagg acttcaagca ggaagttgct gataacctcg gtatttctgt 10020 tgactaattt ttctaagagc tgtaccgcag acaactgcgg tacagccctc taataaaaag 10080 gaggctaacg gctttgaaaa cgaagcttaa gggtattagt tattcaaaat acggatatct 10140 attcagtatt ccttttattg ttgcattctt gatttttacg ctgtatccca ctatatatac 10200 agctaccctc ggttttaccg actgtaaagg cgtaaatggt cctgagaatt atcattttct 10260 ggataagcca tttgaaaact ttaagtctat attagagaat gatactttcc gtatatctct 10320 caagaacacg attcttatct ggataatgaa ctttatccct cagatcagta tcgcacttct 10380 gcttactgct tggttcacat cccacagtaa tgagataagg ggaaagggtt tctttaaagt 10440 cgttttctat atgccgaaca tcatcacagc tgcaacagtt gcgatcctct tccatacact 10500 tttcaactat cctatcggac ctgtaaacga tttcctcgaa agtacaggcc taagagaatc 10560 accgtactat ttctttacaa gtaagacagc gtgcagaata attgtagctt tcatacagtt 10620 ctggacatgg tacggaaata caatgatagt gcttatctca ggtgtacttg gtataagccc 10680 tgacatttat gaagcggcag agatcgacgg agcgaacggt gttcagacct tcttccgtat 10740 tacaatacct aatttaaaga cagtgttgct ttatacactg ataaccagcc ttgtcggcgg 10800 acttaatatg ttcgatattc cgttcctgtt cctcaacggc ggacctgaca gagctacaac 10860 aactacaagc gtattcattt acaatcaggc tttcgcgggc agctacctgt ataataaggc 10920 tgcggcggca agtatgatca tgtgggtaat cattgctctc tgttcagctg tattgttctt 10980 tgtgatgcga gacaaggatc agataaagct ggagaaggag atcaagagag ccaaaaaaga 11040 agctaaattg gcgtcgaaag gaggagtaaa tcagtggcag tggtgaataa aaagccggga 11100 agttacgctt tcaaaatcat tgcgtataca ttctgtttac tcttaacagt gctcagttta 11160 tttccgttcg ttatcatgat c 11181 // |
|