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EBI DbfetchID AJ001836; SV 1; linear; genomic DNA; STD; FUN; 4947 BP. XX AC AJ001836; XX DT 03-FEB-1998 (Rel. 54, Created) DT 14-NOV-2006 (Rel. 89, Last updated, Version 5) XX DE Emericella nidulans three gene cluster for homogentisate degradation XX KW fahA gene; fumarylacetoacetate hydrolase; hmgA gene; KW homogentisate dioxygenase; maiA gene; maleylacetoacetate isomerase. XX OS Emericella nidulans OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Emericella. XX RN [1] RP 1-4947 RA Penalva M.A.; RT ; RL Submitted (08-OCT-1997) to the EMBL/GenBank/DDBJ databases. RL Penalva M.A., Molecular Microbiology, Centro de Investigaciones Biologicas RL CSIC, Velazquez 144, Madrid, 28006, SPAIN. XX RN [2] RX DOI; 10.1074/jbc.273.1.329 RX PUBMED; 9417084. RA Fernandez-Canon J.M., Penalva M.A.; RT "Characterization of a fungal maleylacetoacetate isomerase gene and RT identification of its human homologue"; RL J. Biol. Chem. 273(1):329-337(1998). XX DR RFAM; RF00005; tRNA. XX FH Key Location/Qualifiers FH FT source 1..4947 FT /organism="Emericella nidulans" FT /chromosome="VII" FT /mol_type="genomic DNA" FT /db_xref="taxon:162425" FT CDS 320..1012 FT /codon_start=1 FT /gene="maiA" FT /product="maleylacetoacetate isomerase" FT /EC_number="5.2.1.2" FT /db_xref="GOA:O43123" FT /db_xref="HSSP:1FW1" FT /db_xref="InterPro:IPR012335" FT /db_xref="UniProtKB/Swiss-Prot:O43123" FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="CAA05041.1" FT /translation="MSTNSDLRVTLYTYFRSSCSARLRIALALRSISYTSVPINLLKGE FT QSSTKNTAVNPSATVPTLIIEHVDRSQSPITITQSLAALEYLDEAFPDNPNPLLPPISN FT PQQRALVRSLASIIACDIQPVTNLRILQRVAPFGVDRAAWSKDLIEAGFAAYEAIARDS FT AGVFSVGDTITMADVCLIPAVWGAERAGVNLGQYPTIKRVAEALEKENAVKEGHWRTQQ FT DTPTEFRC" FT CDS join(3209..3276,3325..3828,3883..4533,4583..4706) FT /codon_start=1 FT /gene="hmgA" FT /product="homogentisate dioxygenase" FT /EC_number="1.13.11.15" FT /db_xref="GOA:Q00667" FT /db_xref="HSSP:1EYB" FT /db_xref="InterPro:IPR005708" FT /db_xref="UniProtKB/Swiss-Prot:Q00667" FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="CAA05042.1" FT /translation="MPVTEFSFKDPYTYQNGFDSYHESEAIEGALPVGHNSPQKAPYGL FT YAEKLSGTAFTAPRHENKQTWVYRILPAAAHENFVEEDASSYHTLSDAKKLQHIPNQLR FT WDPFDLDETVDWVHGLHLVAGSGDPTVKQGLGILLYAAGKDMGKEAFYSADGDFLIVAQ FT HGVLDIQTELGRLLVRPNEICVIPRGVRYRVTLPDGPVRGYICELYQGHYQLPELGPIG FT SNGLANARDFQAPVAAFDDEEGPTEYRLYSKFNNHLFSARQDHTPFDIVAWHGNYYPYK FT YDLGRFNTMGSVSFDHPDPSIYTVLTGPSDHVGTAIADFVIFPPRWLVAEKTFRPPWYH FT RNTMSEFMGLITGNYDAKTGGGFQPAGASLHNIMSAHGPDMHAFEGASNADLKPTKIGD FT GSMAFMFESSLMVGVSEWGLKTCQKVQEEYNEHSWQPLKRHFKDPRKAQ" FT exon 3209..3276 FT /gene="hmgA" FT /number=1 FT intron 3277..3324 FT /gene="hmgA" FT /number=1 FT exon 3325..3828 FT /gene="hmgA" FT /number=2 FT intron 3829..3881 FT /gene="hmgA" FT /number=2 FT exon 3883..4533 FT /gene="hmgA" FT /number=3 FT intron 4534..4582 FT /gene="hmgA" FT /number=3 FT exon 4583..4706 FT /gene="hmgA" FT /number=4 FT CDS complement(1499..2794) FT /codon_start=1 FT /gene="fahA" FT /product="fumarylacetoacetate hydrolase" FT /EC_number="3.7.1.2" FT /db_xref="GOA:Q00770" FT /db_xref="HSSP:1HYO" FT /db_xref="InterPro:IPR015377" FT /db_xref="UniProtKB/Swiss-Prot:Q00770" FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="CAA05043.1" FT /translation="MASWLQIPKNSPFSLANIPFGIISSSKLSSRVPAIAIGDYALDLS FT KFASSGGFSQLPVIQPHLNVFKESTLNAFAALGRPVHRQVREYIQKVFSTETPFPQILR FT DNAALQKEALLPLSEVTNHLPMQIGDYTDFYAGLNHAYNVGVLFRGPDNALQPNYKHLP FT VAYHGRASSVVTSGTPLHRPQGQILTNPAANPKLPTFSPCKKLDIELELAFFVSTPNDL FT GHPVHIDKAEDHIFGVVLMNDWSARDIQAWEYVPLGPFNAKNFGTTITPWVVLIDALEP FT FRTVGLEPGNRESLLPYLREKRADTAYDIPLEVEVTNAGGEPTVISRSNAKNLLYSFPQ FT MLAHHTITGCNLNTGDLLGSGTISGKENQTEGSFLEQTNGKNPIKLADGSERLFLEDGD FT TVILRGMAGTEGNYVGFGDCAGTILPPVQLDL" XX SQ Sequence 4947 BP; 1255 A; 1281 C; 1261 G; 1150 T; 0 other; ccgcgggaat ttgcgcgtcc agcagcggat attccatcgc ggaatccctt cggccacccc 60 gcatctatca tttttcgaac gtgctcgccg caaaaagaat cacgtagcga aactaggaat 120 gaataggaaa tcgccgtgga tacccttggc cagagccttg aatacgagcg attccgagtt 180 tatcctctag atagagaact gcatcgatga acacttccaa cgcaccacct tttccctcta 240 gcagactcaa accgtttcca agcaacaaac cctagtcaag actgcaatat ctacttaaag 300 ggacaccgca ccggtcaaga tgtctacaaa ttcagacctc agagtgacac tctacaccta 360 ctttcgctcc tcgtgctccg cgcgccttcg tatcgccctc gcccttaggt caatctccta 420 tacctcagtc cctatcaacc tgctgaaggg cgagcagtcg agcacaaaaa acacggccgt 480 aaacccatcg gccaccgttc ccacgctcat catcgagcat gtagaccgga gccagtctcc 540 aataacaata acccagtccc tcgcagcgct cgaatacctg gatgaagcat tccccgacaa 600 tcccaaccca ctccttccac ctatttctaa cccgcaacaa cgcgcgctcg tgaggtctct 660 agcatcaatt atagcctgcg acattcagcc agtcacgaac ctacggattc ttcagcgcgt 720 tgcaccattc ggcgtcgacc gggccgcctg gtcaaaggat ctcattgaag ctgggtttgc 780 ggcgtatgag gctattgcta gagactctgc tggagtattc agtgttggcg atacaatcac 840 gatggcggat gtttgtttga tccccgctgt ttggggcgca gagagagcgg gggtaaatct 900 gggacagtat cctacaatta aaagggttgc ggaggccctg gagaaggaga atgcagttaa 960 ggaggggcat tggagaaccc agcaggatac accaacggaa ttcaggtgtt gaatctgctg 1020 cttggcgacc gatgttccat tgtcggaacg aaaatgttat acaggccggt cttgaatgat 1080 ggacggggtt tactgcgaga gtaaaaggtt atcgacaagt tcggacagga gtctctgcgt 1140 acccttgcgc taaataagag taatgtaaat gacctgcaaa gcatctccaa agaagacccg 1200 agtagcaaat aaaaaagtca aaaaaaagta tggtcccgga ggggatcgaa ccctcagcct 1260 tggcgttatt agcaccacgc gctaaccaat tgcgccacgg aacccgcttg ctgaaatatt 1320 tcaaattact actaatctat attcttagtg aaaaaggagc gcagtaatgt ccccagaagc 1380 cgccaatttt tgcctgaaag tgttgccaaa tataactact cagctctggg gtaaaaaaaa 1440 acctagcatt gccatcaagc ttgaaatatc tcattttatt ttaactattg catgcgaatc 1500 acagatccag ctgcacaggc ggcaaaattg ttccggcaca atcgccaaac cctacatagt 1560 tgccttcagt tcccgccata ccacgcagaa taacagtgtc accgtcctct aagaacaagc 1620 gctcggagcc atctgcgagc ttgataggat tctttccatt ggtttgctcg aggaaactgc 1680 cttcggtctg attctccttg ccagagatcg taccactgcc gaggagatca ccggtgttca 1740 ggttgcagcc cgttatggtg tggtgggcca gcatctgagg gaaagagtac aggaggttct 1800 ttgcattgct gcgggagata acagtaggct cgccgcctgc attggtgact tcgacctcca 1860 gcgggatatc ataggcagtg tcagcccgct tctcccgcag atacggtagg agagactccc 1920 tgtttccggg ttctagaccg acggtgcgga agggctcgag agcatcaatc aggacaaccc 1980 agggggtgat cgttgtgcca aagttctttg cgttaaaggg accaagagga acgtactccc 2040 atgcctggat gtcacgggca gaccagtcgt tcataagcac cactccgaag atatggtctt 2100 cggctttgtc gatatgaacc ggatgcccta gatcattggg agttgagacg aaaaacgcta 2160 actccagttc gatatcgagc ttcttgcaag gagagaaggt gggtaattta gggtttgccg 2220 cgggattcgt caagatctgg ccctgtggac ggtggagagg cgtgccggag gtgaccacag 2280 acgaggcacg gccatggtaa gccacgggga gatgtttata atttggctgt agggcattgt 2340 cgggtcccct gaagaggact ccaacgttgt aagcatggtt aaggccggcg tagaaatctg 2400 tgtaatcgcc gatctgcatg gggagatggt ttgtaacctc agacagcggc aggagggcct 2460 ctttctggag cgctgcattg tctctgagga tttgaggaaa aggcgtctct gtgctgaaga 2520 ccttctgaat gtattcacgg acttgtcggt gcactggtcg accaagagct gcgaacgcgt 2580 tcagggtgga ttccttgaag acattcagat gaggctggat gacgggaagc tgggagaaac 2640 cgccagacga ggcaaatttg ctcaagtcta aggcataatc tccgatcgca atagcgggaa 2700 ctcgcgacga gagcttcgat gatgaaatga taccgaatgg gatgtttgcc agcgagaaag 2760 gcgagttctt ggggatttgt aaccacgaag ccattgtgac gggagctagc aaaaattagg 2820 agagaatggt agatgaatga ttcaggagac aacgaagacc aaataacaga taaaacgctg 2880 ctgagagaga tgtcgacata gaacggggca ggaaggattc cgtacgagga gctgcagcac 2940 cgcggaatga agccgcaccc gcttatcacc ggctgttgtg tttccccagt gtgatcccga 3000 ctttccgcag cccctctttg tcgccctgaa gtgaaggtcg ccgctggccg ggcggattgc 3060 gggaattcag ctttctggga agtcatgggt tgatctggag ttctgtcaca tttcttctgc 3120 ctatgtgcta gctaagtata taggccgagt cctcactgtc cctgcagcag cacccgatat 3180 ccaacgtgac aaaccataca ctatcaacat gccagtcacc gagttctcct tcaaagatcc 3240 ttacacctat cagaatgggt tcgattctta ccatgagtat gctactgggt actgaatcga 3300 tgctactgag ctaacttgac ttagatctga agccatcgaa ggcgccctcc ccgtagggca 3360 caactctccc cagaaagctc cttacggctt atatgccgaa aagctctctg ggaccgcttt 3420 cactgctccc cggcacgaga acaaacagac ttgggtctac cgtatccttc ccgccgcagc 3480 gcacgagaac ttcgttgaag aggatgcgag ctcttaccac acgctctcag atgccaaaaa 3540 gcttcagcat atccccaacc agctacggtg ggatccattc gatctggacg agaccgtcga 3600 ctgggttcat gggttgcacc ttgtggctgg ttctggagac cctaccgtaa aacaaggcct 3660 gggcatcttg ctgtatgcgg cggggaaaga tatgggaaag gaagctttct actccgcgga 3720 tggcgacttc ctgatcgtag cacagcatgg cgtgctcgat attcagactg agcttggccg 3780 cttgctggtt cggccgaacg agatttgcgt gattcctcgt ggtgtaaggt ttgtactacg 3840 cgctgacaaa ccatatttga gatcatgagc ttacggaata agataccgtg ttaccctacc 3900 cgacggtcct gtgagaggct acatttgcga gctctaccag ggccactatc agctacccga 3960 attaggacct attggatcca acggtcttgc gaatgcacga gactttcaag caccagtggc 4020 tgcctttgac gacgaggaag gaccgacgga ataccgactg tacagcaagt tcaacaacca 4080 cctcttctcc gcgcgccagg atcacacccc ttttgacatt gtcgcatggc atggcaacta 4140 ctacccctac aaatatgacc ttggccgctt caacaccatg ggctccgtat cattcgacca 4200 ccctgacccc tccatctaca cggtgctcac cggcccgtcc gatcatgtgg gtactgctat 4260 tgctgacttt gttatttttc cgccgcgctg gttggttgcg gagaaaactt tccggcctcc 4320 ctggtatcac cgcaatacta tgtcagaatt catgggtttg atcaccggaa actatgatgc 4380 gaagactggt ggcggcttcc aacctgctgg cgcgagtctg cacaacatca tgagtgcaca 4440 tgggccggac atgcatgcat tcgagggagc aagcaacgcg gacctgaaac ctacgaagat 4500 tggggatggc agcatggctt tcatgtttga aaggtaggtc aacctgtctt ttttccaagt 4560 tcgaaatact aactttgcat agctccctca tggttggcgt gtcggagtgg ggtcttaaga 4620 catgccagaa ggtgcaggag gagtataacg aacatagctg gcagcccttg aagaggcact 4680 tcaaggatcc aaggaaggcc cagtgattct gagtaacttt tatcttggag aaaaactgtg 4740 atataccagc atgaattact gaagcgcttt gtaataggtt taaaacatta tttttgacaa 4800 gttcaaagcc aaacatatcc tggaagtagc cacattaggt ttcacttcta ctcaaaaaac 4860 tatacgccct caacctcctt cctcatcgcc tccttcacga ttgccccaca catcttcgca 4920 tacggattcg tttgcacagc catctgc 4947 // |
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