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EBI DbfetchID AF401529; SV 1; linear; genomic DNA; STD; PRO; 12388 BP. XX AC AF401529; XX DT 24-SEP-2001 (Rel. 69, Created) DT 26-APR-2006 (Rel. 87, Last updated, Version 4) XX DE Campylobacter jejuni O:23 heptosyltransferase I (waaC) gene, partial cds; DE lipid A biosynthesis acyltransferase (htrB), putative two-domain DE glycosyltransferase, putative glycosyltransferase, truncated DE beta-1,4-N-acetylgalactosaminyltransferase (cgtA-I), truncated DE beta-1,3-galactosyltransferase (cgtB), bifunctional DE alpha-2,3/-2,8-sialyltransferase (cst-II), sialic acid synthase (neuB1), DE putative N-acetylglucosamine-6-phosphate 2-epimerase (neuC1), DE beta-1,4-N-acetylgalactosaminyltransferase (cgtA-II), CMP-Neu5Ac synthetase DE (neuA1), putative acetyltransferase, and putative glycosyltransferase DE (waaV) genes, complete cds; and heptosyltransferase II (waaF) gene, partial DE cds. XX KW . XX OS Campylobacter jejuni OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; OC Campylobacteraceae; Campylobacter. XX RN [1] RP 1-12388 RX DOI; 10.1074/jbc.M108452200 RX PUBMED; 11689567. RA Gilbert M., Karwaski M.F., Bernatchez S., Young N.M., Taboada E., RA Michniewicz J., Cunningham A.M., Wakarchuk W.W.; RT "The genetic bases for the variation in the lipo-oligosaccharide of the RT mucosal pathogen, Campylobacter jejuni. Biosynthesis of sialylated RT ganglioside mimics in the core oligosaccharide"; RL J. Biol. Chem. 277(1):327-337(2002). XX RN [2] RP 1-12388 RX DOI; 10.1074/jbc.M512183200 RX PUBMED; 16481326. RA Houliston R.S., Endtz H.P., Yuki N., Li J., Jarrell H.C., Koga M., RA van Belkum A., Karwaski M.F., Wakarchuk W.W., Gilbert M.; RT "Identification of a sialate O-acetyltransferase from Campylobacter jejuni: RT demonstration of direct transfer to the C-9 position of terminalalpha-2, RT 8-linked sialic acid"; RL J. Biol. Chem. 281(17):11480-11486(2006). XX RN [3] RP 1-12388 RA Gilbert M., Michniewicz J., Karwaski M.-F., Cunningham A., Wakarchuk W.W.; RT ; RL Submitted (22-JUL-2001) to the EMBL/GenBank/DDBJ databases. RL Institute for Biological Sciences, National Research Council of Canada, 100 RL Sussex Drive, Ottawa, Ontario K1A 0R6, Canada XX DR StrainInfo; 112649; ATCC 43449. XX FH Key Location/Qualifiers FH FT source 1..12388 FT /organism="Campylobacter jejuni" FT /strain="ATCC 43449" FT /serotype="O:23" FT /mol_type="genomic DNA" FT /db_xref="taxon:197" FT gene <1..348 FT /gene="waaC" FT CDS <1..348 FT /codon_start=1 FT /transl_table=11 FT /gene="waaC" FT /product="heptosyltransferase I" FT /db_xref="GOA:Q93D00" FT /db_xref="InterPro:IPR002201" FT /db_xref="UniProtKB/TrEMBL:Q93D00" FT /protein_id="AAL05998.1" FT /translation="FAKEVLNLSGIDETHIELAPKFSLEELMAFTKMVDLIIGNDSGPT FT HLAFALNKASITIFGATPSYRNAFQTHINKIIDAGKKIQNAKHIDKSDFCITRIEEGDI FT FKLAKGLLNEK" FT gene 338..1225 FT /gene="htrB" FT CDS 338..1225 FT /codon_start=1 FT /transl_table=11 FT /gene="htrB" FT /product="lipid A biosynthesis acyltransferase" FT /db_xref="GOA:Q93CZ9" FT /db_xref="InterPro:IPR004960" FT /db_xref="UniProtKB/TrEMBL:Q93CZ9" FT /protein_id="AAL05999.1" FT /translation="MKNSDRIYLSLYYILKFFVTFMPECILHFLALIVARITFYLNKKH FT RKIIDTNLQICFPQYTQKERDKLSLKIYENFAQFGIDCLQNQNTTKEKILNKVNFINEN FT FLIDALALKRPIIFTTAHYGNWEILSLAYAAKYGAISIVGKKLKSEVMYEILSQSRTQF FT DIELIDKKGGIRQMLSALKKERALGILTDQDCVENESVRLKFFNKEVNYQMGASLIAQR FT SNALIIPVYAYKEDGKFCIEFFKAKDSQNASLEELTLYQAQSCEEMIKKRPWEYFFFHR FT RFASYNEEIYKDAK" FT CDS 1222..2769 FT /codon_start=1 FT /transl_table=11 FT /product="putative two-domain glycosyltransferase" FT /note="orf3" FT /db_xref="GOA:Q93CZ8" FT /db_xref="InterPro:IPR001173" FT /db_xref="InterPro:IPR019290" FT /db_xref="UniProtKB/TrEMBL:Q93CZ8" FT /protein_id="AAL06000.1" FT /translation="MNLKQISVIIIVKNAEQTLLECLNSLKDFDEIILLNNESSDNTLN FT IANEFKKDFANLYIYHSAFIGFGALKNLALSYAKNDWILSIDADEVLENECIKELKNLE FT LQEDNIIALSRKNLYKGEWIKACGWSPDYVLRIFNKNFTRFNDNLVHESLVLPSNVKKI FT HLKNGLRHYAFRDISHLINKMQYYSSLWAKQNIHKKSGVLKANLRAFWTFFRNYFLKNG FT FLYGYQGFTISVCNALGTFFKYMKLYELQKQKPKTCALIITTYNQKERLKLVLDSVKNL FT TFLPNEVLIADDGSKEDTARLIEEYQKDFPCSLKHIWQEDEGFRAAKNRNNAIRVSKSE FT YIILIDGDMILEKDFIKNHFEFAKRKVILQGSRVILNKNESEEILKNDDYSLAFSKKDF FT KSYKNSFLAKIIYKISKIDQKFFNTKEIIKGSKTCNMSFFKADFDELDGFNENFIGWGR FT EDSEFVARFLFNKGIFRRLKFKAIAYHIYHEENSKKMLESNHQTYLDTIKNKKISWR" FT CDS 2773..3846 FT /codon_start=1 FT /transl_table=11 FT /product="putative glycosyltransferase" FT /note="orf4" FT /db_xref="GOA:Q93CZ7" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q93CZ7" FT /protein_id="AAL06001.1" FT /translation="MKKIGVVIPIYNVEEYLRECLDSVINQTYTNLEIILVNDGSTDEN FT SLNIAKEYTLKDERFILFDKKNGGLSSARNVGIEYFSGEYKLKNKTQHIKENSLIEFQL FT DGNNPYNIYKAYKSSQAFNNEKDLTNFTYPNIDYIIFLDSDDYWELNCIEECVIRMKNV FT DVLWFDHDCTYEDNIKNKHKKTRMEIFDFKKECIITPKEYANRALSVGSRDISFGWNGM FT IDFNFLKKIKLKFINFIINEDIHFGIILFASANKIYVLSQKLYLCRLRANSISNHDKKI FT TKANVSEYFKDIYETFGENAKEAKNYLKAASRVTTALKLIEFFKDQKSENALAIKETFL FT PCYAKKALMIKNLKKIL" FT gene 3988..4077 FT /gene="cgtA-I" FT CDS 3988..4077 FT /codon_start=1 FT /transl_table=11 FT /gene="cgtA-I" FT /product="truncated FT beta-1,4-N-acetylgalactosaminyltransferase" FT /note="orf5-I; premature translation stop due to a one bp FT deletion" FT /protein_id="AAL06002.1" FT /translation="MLFQSYFVKIICLFIPFRKIRHKIKKHFY" FT gene complement(5637..5912) FT /gene="cgtB" FT CDS complement(5637..5912) FT /codon_start=1 FT /transl_table=11 FT /gene="cgtB" FT /product="truncated beta-1,3-galactosyltransferase" FT /db_xref="GOA:Q93CZ6" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q93CZ6" FT /protein_id="AAL06003.1" FT /translation="MFKISIILPTYNVEQYIARAIESCINQTFKNIEIIVVDDCGSDES FT IDIAKEYAKKDERIKIIHNEENLGLLRARYEGVKAAGGGIYYVFRP" FT gene 6001..6876 FT /gene="cst-II" FT CDS 6001..6876 FT /codon_start=1 FT /transl_table=11 FT /gene="cst-II" FT /product="bifunctional alpha-2,3/-2,8-sialyltransferase" FT /note="phase-variable gene due to homopolymeric G-tract" FT /db_xref="GOA:Q93CZ5" FT /db_xref="InterPro:IPR009251" FT /db_xref="UniProtKB/TrEMBL:Q93CZ5" FT /protein_id="AAL06004.1" FT /translation="MKKVIISGNGPSLKEIDYSRLPNDFDVFRCNQFYFEDKYYLGKKC FT KAVFYNPSLFFEQYYTLKHLIQNQEYEIELIMCSNYNQAHLENENFVKTFYDYFPDAHL FT GYDFFKQLKEFNAYFKFHEIYFNQRITSGVYMCTVAIALGYKEIYLSGIDFYDNGGGYA FT FDTKQKNLLKLAPNFKNDNSHYIGHSKNTDIKALEFLEKTYEIKLYCLCPNSLLANFIE FT LAPNLNSNFIIQEKNNYTKDILIPSSEAYGKFTKNINFKKIKIKENIYYKLIKDLLKLP FT SDIKHYFKGK" FT gene 6877..7917 FT /gene="neuB1" FT CDS 6877..7917 FT /codon_start=1 FT /transl_table=11 FT /gene="neuB1" FT /product="sialic acid synthase" FT /db_xref="GOA:Q93CZ4" FT /db_xref="InterPro:IPR006190" FT /db_xref="InterPro:IPR013132" FT /db_xref="InterPro:IPR013785" FT /db_xref="InterPro:IPR013974" FT /db_xref="InterPro:IPR020007" FT /db_xref="UniProtKB/TrEMBL:Q93CZ4" FT /protein_id="AAL06005.1" FT /translation="MKEIKIQNIIISEEKAPLVVPEIGINHNGSLELAKIMVDAAFSAG FT AKIIKHQTHIVEDEMSKAAKKVIPGNAKISIYEIMQKCALDYKDELALKEYTEKLGLVY FT LSTPFSRAGANRLEDMGVSAFKIGSGECNNYPLIKHIAAFKKPMIVSTGMNSIESIKPT FT VKILLDNEIPFVLMHTTNLYPTPHNLVRLNAMLELKKEFSCMVGLSDHTTDNLACLGAV FT ALRACVLERHFTDSMHRSGPDIVCSMDTQALKELIIQSEQMAIMRGNNESKKAAKQEQV FT TIDFAFASVVSIKDIKKGEVLSMDNIWVKRPGLGGISAAEFENILGKKALRDIENDTQL FT SYEDFA" FT gene 7914..9038 FT /gene="neuC1" FT CDS 7914..9038 FT /codon_start=1 FT /transl_table=11 FT /gene="neuC1" FT /product="putative N-acetylglucosamine-6-phosphate FT 2-epimerase" FT /db_xref="GOA:Q93CZ3" FT /db_xref="InterPro:IPR003331" FT /db_xref="InterPro:IPR020004" FT /db_xref="UniProtKB/TrEMBL:Q93CZ3" FT /protein_id="AAL06006.1" FT /translation="MKKILFITGTRADYSKIKSLMYRVQNSSEFELYIFATGMHLSKNF FT GYTVKELYKNGFKNIYEFINYDKYYQTDKALATTIDGFSRYVNELKPDLIVVHGDRIEP FT LAAAIVGALNNILVAHIEGGEISGTIDDSLRHAISKLAHIHLVNDEFAKRRLMQLGEDG FT KSIFIIGSPDLELLNNNKISLNEAKKYYDINYENYALLMFHPVTTEITSIKNQADNLVK FT ALIQSNKNYIVIYPNNDLGFELILQSYEELKNNPRFKLFPSLRFEYFITLLKNADFIIG FT NSSCILKEALYLKTAGILVGSRQNGRLGNENTLKVNANSDEILKAINTIHKKQDLFSTK FT LEILDSSKLFFEYLLSGEFFKLSTQKVFKDIKHA" FT gene 9031..9978 FT /gene="cgtA-II" FT CDS 9031..9978 FT /codon_start=1 FT /transl_table=11 FT /gene="cgtA-II" FT /product="beta-1,4-N-acetylgalactosaminyltransferase" FT /note="orf5-II; phase-variable gene due to homopolymeric FT G-tract" FT /db_xref="GOA:Q934C5" FT /db_xref="InterPro:IPR010446" FT /db_xref="UniProtKB/TrEMBL:Q934C5" FT /protein_id="AAL06007.1" FT /translation="MLKKIISLYKRYSISKKLVLDNEHFIKENKNIYGKKHKGFFDFDE FT KAKDVKSPLNPWGFIRVKNEALTLRVSLESILPALQRGIIAYNDCDDGSEELILEFCKQ FT YPNFIAKKYPYKVDLENPKNEENKLYSYYNWAASFIPLDEWFIKIDVDHYYDAKKLYKS FT FYRIDQENKALCYPRINFIILNGNIYVQNSGNYGFIGGGDQLLIKRRNSSFIERRVSKK FT SQWIDPKGLIEELYSEQQVLSQGVKILQAPLLQWHFPALKYRRNDYQQYLDILSLEEFQ FT AFHRKSKEAKKIDFAMLKRPVIEQILKKFQGEIK" FT gene 9975..10640 FT /gene="neuA1" FT CDS 9975..10640 FT /codon_start=1 FT /transl_table=11 FT /gene="neuA1" FT /product="CMP-Neu5Ac synthetase" FT /db_xref="GOA:Q933W2" FT /db_xref="HSSP:1EYR" FT /db_xref="InterPro:IPR003329" FT /db_xref="UniProtKB/TrEMBL:Q933W2" FT /protein_id="AAL06008.1" FT /translation="MSLAIIPARGGSKGIKNKNLVLLNNKPLIYYTIKAALNAKSISKV FT VVSSDSDEILNYAKSQNVDILKRPISLAQDDTTSDKVLLHALKFYKDYEDVVFLQPTSP FT LRTNIHIDKAFNLYKNSNANALISVSECDNKILKAFVCNDYGDLAGICNDEYPFMPRQK FT LPKTYMSNGAIYILKIKEFLNNPSFLQNKTKHFLMDESSSLDIDCLEDLKKVEQIWKK" FT CDS 10628..11461 FT /codon_start=1 FT /transl_table=11 FT /product="putative acetyltransferase" FT /db_xref="GOA:Q93CZ2" FT /db_xref="HSSP:1MR9" FT /db_xref="InterPro:IPR011004" FT /db_xref="UniProtKB/TrEMBL:Q93CZ2" FT /protein_id="AAL06009.1" FT /translation="MEKITLKCNKNILNLLKQYNIYTKTYIENPRRFSRLKTKDFITIP FT LKNNQLESAAGLGIEEYCAFKFSNILHEMGSFSFSGSFLPHYAKVGRYCSIADGVSMFN FT FQHPIDRISTASFTYETNHSFINDACQNHINKTFPIVNHNPSSSITHLIIQDDVWIGKD FT VLLKQGITLGTGCVIGQRAVVTKDVPPYAIVAGIPAKIIKYRFDEKTIERLLKIQWWRY FT HFADFYDIDLNLKINQYLDLLEEKIIKKSISYYNPNKLYFRDILELKSKKIFNLF" FT gene complement(11510..12364) FT /gene="waaV" FT CDS complement(11510..12364) FT /codon_start=1 FT /transl_table=11 FT /gene="waaV" FT /product="putative glycosyltransferase" FT /db_xref="GOA:Q93CZ1" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q93CZ1" FT /protein_id="AAL06010.1" FT /translation="MGRCIKIFINFLNFDRIVFIILTKFRKNMPQLSIIIPLFNSCDFI FT LRALQSCINQTLKDIEILIIDDKSKDNSLNMVLEFAKKDPRIKIFQNEENLGTFASRNL FT GVLHSSSDFIMFLDSDDFLTPGACEIAFKEMKKGFDLLCFDAFVHRVKTKQFYRFKQDG FT VFNQKEFLEFLSKQRHFCWSVWAKCFRKDIILKNFEKVKFEKVKIDERLSYGEDVLFCY FT IYFMFCEKIAVFKTCIYHYEFNPNGRYENKNKEILNQNYYDKKKSNEIIKRLSKEFLHD FT EFH" FT gene 12261..>12388 FT /gene="waaF" FT CDS 12261..>12388 FT /codon_start=1 FT /transl_table=11 FT /gene="waaF" FT /product="heptosyltransferase II" FT /db_xref="GOA:Q7BN90" FT /db_xref="UniProtKB/TrEMBL:Q7BN90" FT /protein_id="AAL06011.1" FT /translation="MIESCGIFFLNFVKIIKTILSKFRKFMKIFIHLPTWLGDTVMA" XX SQ Sequence 12388 BP; 4843 A; 1620 C; 1811 G; 4114 T; 0 other; tttgctaaag aggttttaaa tcttagtggt attgatgaaa cacatataga attagcgcca 60 aaatttagcc ttgaagagtt aatggctttt acaaaaatgg tggatcttat cataggaaat 120 gatagtggtc caacacattt agcttttgct ttaaacaaag catctattac gatttttggt 180 gcaacaccaa gctaccgcaa tgcttttcaa acccatatca ataaaatcat tgatgcaggt 240 aaaaaaatcc aaaatgccaa gcatatcgat aaaagtgatt tttgtatcac gcgtatagaa 300 gaaggagata tcttcaaact tgccaaaggc ttacttaatg aaaaatagcg atagaatata 360 tcttagtctt tattatattt tgaaattttt tgttactttt atgcctgagt gtatcttgca 420 ttttttagct ttgattgtag caagaatcac tttttatctt aacaaaaaac atcgcaaaat 480 catcgataca aatttgcaaa tctgcttccc tcaatacact caaaaagaac gagataaatt 540 gtctttgaaa atttatgaaa attttgctca atttggaatt gattgtttgc aaaatcaaaa 600 caccaccaag gaaaaaattc tcaataaagt aaattttatc aatgaaaatt ttcttataga 660 cgctctagct ttaaagcgtc ctattatctt cacaactgca cactatggaa actgggaaat 720 tttaagcctt gcttatgcag ctaaatatgg tgcgatctcc atagtgggaa aaaagttaaa 780 aagtgaagtt atgtatgaaa ttttaagcca aagtcgcacc caatttgaca tagaacttat 840 cgacaaaaaa ggcggtataa gacaaatgct aagtgctcta aaaaaagagc gagctttggg 900 aattttaacc gatcaagact gcgtagaaaa cgaaagcgta agattaaaat tttttaacaa 960 agaagtgaat tatcaaatgg gagcaagcct tatcgcacaa agaagcaatg ctttgatcat 1020 ccctgtttat gcctataaag aagatggtaa attttgcata gagtttttta aagcaaaaga 1080 ttctcaaaat gcaagtttag aagaactgac actttatcaa gcacaaagtt gcgaagaaat 1140 gattaaaaaa agaccttggg aatacttttt tttccataga cgctttgcaa gttataatga 1200 ggaaatttac aaggatgcaa aatgaatcta aagcaaataa gcgttattat catcgtaaaa 1260 aatgcagagc aaaccttgct tgagtgttta aattctttaa aagattttga tgaaattatt 1320 ttacttaaca atgaaagtag tgataatacc ctaaatatag ctaatgaatt taaaaaagat 1380 tttgctaatt tgtacattta ccacagtgct tttataggtt ttggagcttt aaaaaatctt 1440 gctttaagct atgcaaaaaa tgattggatt ttaagcattg atgctgatga agtacttgaa 1500 aatgagtgta ttaaagagct taaaaattta gaacttcaag aagataatat catcgcactt 1560 agtcggaaaa atctctataa aggcgaatgg ataaaggctt gtggttggtc gcctgattat 1620 gttttaagaa tttttaataa aaatttcact cgttttaatg ataatttagt gcatgaaagc 1680 cttgttttac caagtaatgt taaaaaaatt catcttaaaa atggattaag gcattatgct 1740 tttagagata tttctcactt aatcaataaa atgcagtact actcaagcct ttgggcaaaa 1800 caaaatatac ataaaaaaag tggtgtttta aaagcaaatt taagagcttt ttggactttt 1860 tttagaaatt attttttaaa aaatggcttt ttgtatggtt atcaaggctt tacgatcagc 1920 gtttgcaatg ccttagggac tttttttaaa tatatgaaat tatatgaact tcaaaagcaa 1980 aagccaaaaa cttgtgcttt aataataaca acctataatc aaaaagaacg ccttaaatta 2040 gtgcttgata gtgttaaaaa tctaaccttt ttacccaatg aagttttaat cgcagatgat 2100 ggtagcaaag aagatacagc aaggcttatt gaagaatatc aaaaagattt tccttgctct 2160 ttaaaacaca tttggcaaga agatgagggt tttcgcgctg caaaaaatag aaataatgcc 2220 attagagttt ctaaaagtga atatataatt ttaattgacg gtgatatgat tttagaaaaa 2280 gactttataa aaaatcattt cgaatttgcg aaacgcaaag taattttaca aggttcaaga 2340 gtaattttaa ataaaaatga aagcgaagaa atcttaaaaa atgatgatta tagtttagct 2400 tttagtaaaa aagattttaa aagctataaa aattcttttt tagccaaaat tatctataaa 2460 atttcaaaaa tagatcaaaa attttttaat accaaagaaa taataaaggg aagtaaaacc 2520 tgcaatatga gtttttttaa agccgatttt gatgaacttg atggttttaa tgaaaatttt 2580 attggttggg gtagagaaga tagtgaattt gtggctagat ttttatttaa taaaggcatt 2640 tttagacgct taaaatttaa agctattgct tatcatattt atcatgaaga aaatagcaaa 2700 aaaatgctcg aaagcaatca tcaaacttat ttagatacca tcaaaaataa aaaaatttct 2760 tggagataaa acatgaagaa aataggtgta gttataccaa tatacaacgt agaagaatat 2820 ttgagagaat gtttagacag cgtcatcaat caaacttata ctaacttaga aatcatactt 2880 gtaaatgatg gtagtacaga tgaaaactca ctcaatatag ccaaagaata tactttaaaa 2940 gatgaaagat ttatactttt tgataagaaa aatgggggtt taagttcagc tagaaatgta 3000 ggtatagaat actttagtgg ggagtataaa ttaaaaaaca aaactcaaca tataaaagaa 3060 aattctttaa tagaatttca attggatggt aataatcctt ataatatata taaagcatat 3120 aaaagctctc aagcttttaa taatgaaaaa gatttaacta attttactta tcctaatata 3180 gattatatta tatttttaga tagtgatgat tattgggagt taaactgcat agaagaatgt 3240 gttataagaa tgaaaaatgt ggatgtattg tggtttgacc atgattgcac ctatgaagac 3300 aatataaaaa ataagcacaa aaaaacaagg atggaaattt ttgattttaa aaaagaatgt 3360 ataatcactc caaaagaata tgcaaatcga gcattaagtg taggatctag agatatttct 3420 tttggatgga atggaatgat tgattttaat tttttaaaga aaattaaact taaatttata 3480 aattttatta tcaatgaaga tatacacttt gggataattt tgtttgctag tgctaataaa 3540 atttatgttt tatcacaaaa gttgtattta tgccgtttaa gagcaaacag tatatcaaat 3600 catgataaga agattacaaa agcaaatgtg tcagagtatt ttaaagatat atatgaaact 3660 ttcggggaaa acgctaagga agcaaaaaat tatttaaaag cagcaagcag ggttacaact 3720 gctttaaaat tgatagaatt ttttaaagat caaaaaagcg aaaatgcact tgctataaaa 3780 gaaacatttt taccttgcta tgccaaaaaa gctttaatga ttaaaaattt aaaaaagatc 3840 ctttaaattt aaaggaacaa ttagttttaa ttaagccttt tattcaaaca aaacttcctt 3900 acgatatttg gaaattttgg caaaaaataa aaaaaattaa ttaattttta ggtacaatca 3960 ctataattat aggagaaaat attttatatg ctatttcaat catactttgt gaaaataatt 4020 tgcttattca ttccttttag aaaaattaga cataaaataa aaaaacattt ttactaaaaa 4080 acatacaacg agataaaatc gattcttatc taccaaaaaa aattcttata caaattaata 4140 aatacaacaa tgaagattta attaaactta ataaagctat tacaggaggg gggcataaag 4200 gatattttaa ttatgatgaa aaatctaaag atccaaaatc tcctttgaat ccttgggctt 4260 ttatacgagt aaaaaatgaa gctattacct taaaagcttc tcttgaaagt atattgcctg 4320 ctatccaaag aggtgttata ggatataatg attgtaccga tggaagtgaa gaaataattc 4380 tagaattttg caaacaatat ccttcattta taccaataaa atatccttat gaaattcaaa 4440 ttcaaaaccc aaaatcagaa gaaaataaac tctatagcta ttataattat gttgcaagtt 4500 ttataccaaa agatgagtgg cttataaaaa tagatgtgga tcattattat gatgcaaaaa 4560 aattatataa gagtttttat atacctagaa aaaattatca tgtaattagt tactctagga 4620 tagattttat atttaatgaa gaaaaatttt atgtttatcg gaataaggag ggggagattt 4680 taaaagctcc tggagattgt ttagcaatac aaaacactaa cttattttgg aaagaaatac 4740 ttattgaaga tgatacattt aagtggaata ctgcaaaaaa taatataaag aatgcaaaat 4800 catatgaaat tttaaaagtt agaaatagaa tttattttac tacagaactt aataattatc 4860 attttccatt tataaaaaat tatagaaaaa atgattataa gcagttaaat tgggttagct 4920 tagatgattt tattaaaaat tataaagaaa aattaaaaaa tcaaatagat tttaaaatgc 4980 tagaatacaa aacattaaaa aaagtgtacg aaaagcttac atcttcagca agcgataaaa 5040 tttaaattgg atttttttaa aaaaaatatt gattttaaaa caaagaacat ttcgcttgct 5100 tgataatgag tatttttcaa ttaataaaaa atactcaatt aatttaagca aagttaagtt 5160 aaaattgtaa ttatattgca tcttctttag aagatataga acattatctt gttcttgtat 5220 atttgttttt atattttgca atgttaatgt tttggttata gagaaattat ttatttgata 5280 attgtataaa tttttactca agtgaaatat agtatttgaa atatttatca aagggtagta 5340 taataaaaca tcttcagcca tatttatttt agcattttct agcgatatta aaccaacagc 5400 cttgagatat aattcttttt ttataacttt tgcccacact gtccaaaata aatttttagt 5460 ttttaatagt tcttttaaaa aatctttttt tgcataacat ttttcttgaa aattcaactt 5520 tctttctatt ttattattat tttccaatac aaatgcatta aaaaaataat aaatctattt 5580 cattgttttt taaaattttc atacattctt cacaagcatt aagttctaaa taatcatcag 5640 ggtctaaaaa cataatatat ccccccccca gctgccttaa ctccttcata tctagctctt 5700 aaaagaccta aattttcttc attgtgaatt atttttattc tttcatcttt tttggcatat 5760 tctttagcta tatctatact ttcatcactc ccacaatcat caactacaat tatttctata 5820 tttttaaaag tctgattgat acaactttct attgcccttg ctatatattg ttccacatta 5880 taagttggta agatgattga aattttaaac atatttattc cttattttat tataatttaa 5940 ttataacata aaatctattt tgataaaatc gttaaaaata aatcttgatg gaaaataatc 6000 atgaaaaaag ttattatttc tggaaatgga ccaagtttaa aagaaattga ttattcaaga 6060 ctaccaaatg attttgatgt atttagatgt aatcaatttt attttgaaga taaatactat 6120 cttggtaaaa aatgcaaagc agtattttac aatcctagtc ttttttttga acaatactac 6180 actttaaaac atttaatcca aaatcaagaa tatgagatcg aactaattat gtgttctaat 6240 tacaaccaag ctcatctaga aaatgaaaat tttgtaaaaa ctttttacga ttattttcct 6300 gatgctcatt tgggatatga ttttttcaaa caacttaaag aattcaatgc ttattttaaa 6360 tttcacgaaa tttatttcaa tcaaagaatt acctcagggg tctatatgtg cacagtagcc 6420 atagccctag gatacaaaga aatttatctt tctggaattg atttttatga taatgggggg 6480 gggtatgctt ttgataccaa acaaaaaaat cttttaaaat tggctcctaa ttttaaaaat 6540 gataattcac actatatcgg acatagtaaa aatacagata taaaagcttt agaatttcta 6600 gaaaaaactt acgaaataaa gctatattgt ttatgtccta acagtctttt agcaaatttt 6660 atagaactag caccaaattt aaattcaaat tttatcatac aagaaaaaaa taactatact 6720 aaagatatac tcataccttc tagtgaggct tatggaaaat ttacaaaaaa tattaatttt 6780 aaaaaaataa aaattaaaga aaatatttat tacaagttga taaaagattt attaaaatta 6840 cctagcgata taaagcatta tttcaaagga aaataaatga aagaaataaa aatacaaaat 6900 ataatcataa gtgaagaaaa agcaccctta gtcgtacctg aaataggcat taatcacaat 6960 ggcagtttag aactagctaa aattatggta gatgcagcct ttagcgcagg tgctaagatt 7020 ataaagcatc aaacccatat cgttgaagat gagatgagta aggccgctaa aaaagtaatt 7080 cctggtaatg caaaaataag catttatgag attatgcaaa aatgcgcttt ggattataaa 7140 gatgagctag cacttaaaga atacacagaa aaattaggtc ttgtttatct tagcacacct 7200 ttttctcgtg caggtgcaaa ccgcttagaa gatatgggag ttagtgcttt taagattggt 7260 tcaggtgagt gtaataatta tccacttatt aaacacatag cagcctttaa aaagcctatg 7320 atagttagca caggaatgaa tagtattgaa agtataaaac caactgtaaa aatcttatta 7380 gacaatgaaa ttccctttgt tttaatgcac acgaccaatc tttacccaac cccgcataat 7440 cttgtaagat taaacgctat gcttgaatta aaaaaagaat tttcttgtat ggtaggctta 7500 agcgaccaca caacagataa tcttgcgtgt ttaggtgcag ttgcacttag agcttgcgta 7560 cttgaaagac attttactga tagtatgcat agaagtggcc ctgatatagt ttgttctatg 7620 gatacacagg ctttaaaaga gcttattata caaagtgagc aaatggctat aatgagagga 7680 aataatgaaa gcaaaaaagc agctaagcaa gaacaagtta caattgattt tgcctttgca 7740 agcgtagtta gtattaaaga tattaaaaaa ggcgaagttt tatctatgga caatatctgg 7800 gttaaaagac ctggacttgg tggaattagt gcggctgaat ttgaaaatat tttaggcaaa 7860 aaagcattaa gagatataga aaatgatact cagttaagct atgaggattt tgcgtgaaaa 7920 aaatcctttt tataacaggt actagggctg attattctaa gattaaatct ttaatgtaca 7980 gggtgcaaaa ctcaagcgaa tttgagcttt acatctttgc aacaggaatg cacttaagca 8040 aaaattttgg ctatacagtt aaagagcttt ataaaaatgg ctttaaaaat atttatgaat 8100 ttataaatta tgataaatat tatcaaactg ataaggcttt agctactaca attgatggat 8160 tttcaaggta tgtaaatgag ctaaaacctg atttaatcgt agtgcatgga gatagaatcg 8220 agcctttagc agcagctatt gttggagcat taaataatat cttagtagca catattgaag 8280 gtggagagat ttcaggaact attgatgata gcttacgcca cgctatatca aaactagctc 8340 atattcattt agtaaatgat gagtttgcaa aaaggcgttt aatgcagctt ggagaagatg 8400 gaaaatctat ttttatcata ggttcgcctg atttagaact tttaaacaat aataaaattt 8460 cacttaatga agcaaaaaaa tattatgata taaattatga aaactacgct ttgcttatgt 8520 ttcatcctgt tacaactgaa attactagca ttaaaaatca agcagataat ttagtaaaag 8580 cactgataca aagtaataaa aattatattg ttatttatcc aaataatgat ttaggttttg 8640 aattaatctt gcaaagctat gaagagctta aaaacaatcc tagatttaag ctttttccat 8700 cgcttagatt tgagtatttt ataactttgt taaaaaatgc tgattttata ataggtaatt 8760 caagttgtat tttaaaagag gccttatact taaaaacagc agggatttta gttggctcaa 8820 gacaaaatgg aagacttggc aatgaaaata cactaaaagt taatgcaaat agtgatgaaa 8880 tactaaaagc tattaacacc attcataaaa aacaagattt atttagcact aagttagaga 8940 ttttagatag ctcaaaatta ttttttgaat atttattaag cggagaattt tttaaactca 9000 gcacacaaaa agtttttaag gatataaaac atgcttaaaa aaatcatttc tttatataaa 9060 agatactcga tttctaaaaa attggtttta gataatgagc atttcattaa ggaaaataaa 9120 aacatctatg gaaaaaaaca taagggcttt tttgactttg atgaaaaggc taaggatgtg 9180 aaatcacccc ttaatccttg gggatttatc agggttaaaa atgaagcttt aaccctaaga 9240 gtttctttag aaagtatact acctgcttta caaagaggaa ttatagctta caacgactgt 9300 gatgatggga gtgaagagct tattttagaa ttttgcaagc aatatcccaa cttcattgct 9360 aaaaaatatc cttataaagt agatctagaa aatcctaaaa atgaagaaaa taaactttac 9420 tcttattaca attgggcagc atcttttata cccttagatg agtggtttat aaaaatcgat 9480 gtggatcatt actacgatgc caagaagctt tataagagtt tttataggat tgatcaagaa 9540 aataaagcct tatgctaccc aagaattaat tttataatct taaatggaaa tatttatgtg 9600 caaaatagtg gaaattatgg attcataggg gggggggatc aactcttgat taaaagaaga 9660 aatagtagct ttatagaaag aagggtttca aaaaaaagcc aatggataga tcctaaggga 9720 cttatagaag aactctactc cgagcaacaa gtcttatctc aaggagtgaa aatactacaa 9780 gctcccctac ttcagtggca ttttcctgcc ttaaaatacc gccgaaacga ttaccaacaa 9840 tatttagata tcttgagttt agaagaattt caggcctttc atcgtaagag caaagaggct 9900 aaaaaaatag actttgccat gctaaaacgc cctgtaatcg agcaaatatt aaagaaattt 9960 caaggagaga taaaatgagc ttagcaataa tccctgctcg tggtggctca aagggtatta 10020 aaaataaaaa tttggtttta ttaaataata aacctttaat ttattacacc attaaagctg 10080 cactaaatgc taaaagcatt agtaaagttg ttgtaagcag tgatagtgat gaaattttaa 10140 attatgcaaa aagccaaaat gttgatattt taaaacgccc aattagcctt gcacaagatg 10200 atactacaag cgataaagtg cttttacatg ctctaaaatt ttacaaagat tatgaagatg 10260 tagttttttt acaacccact tcgccgctaa gaacaaatat tcatattgat aaagctttta 10320 atctttataa aaatagcaat gcaaatgccc taattagcgt aagcgaatgt gataataaaa 10380 ttctaaaagc ctttgtttgt aatgattatg gcgatttagc agggatttgt aatgatgaat 10440 atccttttat gccaaggcaa aaattgccta aaacttatat gagcaatggt gcaatttata 10500 ttttaaagat aaaagaattt ttaaacaatc ctagcttttt gcaaaacaaa accaagcatt 10560 ttttaatgga cgaaagctca agtttagata ttgactgttt agaggattta aaaaaggttg 10620 aacagatatg gaaaaaataa ccttaaaatg caataaaaat atattaaatt tattaaagca 10680 atataatatt tatacaaaaa cttacataga aaatcctaga agattttcaa gactaaaaac 10740 caaagatttt ataaccattc cattgaaaaa caatcaatta gagagtgcgg cggggctggg 10800 gatagaagaa tattgtgctt ttaaatttag caatatctta catgaaatgg gttcattttc 10860 ttttagcgga tcttttctac ctcattatgc aaaagttgga aggtattgtt caattgctga 10920 tggggtttct atgtttaact ttcaacaccc tatagataga atcagcactg caagttttac 10980 ctatgaaaca aatcatagtt ttattaacga tgcttgccaa aatcacatca acaaaacatt 11040 tcctatagtt aaccataatc caagctcatc aataacgcat ttaattatac aagatgatgt 11100 ttggatagga aaagatgttt tgcttaaaca gggtatcaca cttgggactg gatgtgtcat 11160 aggacaaaga gctgtagtta ctaaagatgt accaccttat gctatagttg caggaattcc 11220 agccaaaatt atcaaatata gatttgatga aaaaacaata gaaagattat taaaaattca 11280 atggtggaga tatcattttg ctgattttta tgatattgat cttaatttaa aaataaacca 11340 atatcttgac ctactagaag aaaaaatcat aaaaaaatca atttcctact ataatccaaa 11400 taaactttat tttagagata ttttagaact aaaatcaaaa aaaattttta atctatttta 11460 atctattttt cacccctact tcctctctct ccaaaacttc aaataatttc taatgaaatt 11520 catcatgtaa aaactctttg gagagtcttt ttatgatttc attacttttc tttttatcat 11580 aataattttg atttaaaatt tctttatttt tattctcata tcttccattt ggattaaatt 11640 cgtaatgata aatgcaagtt ttaaaaacag ctattttctc gcaaaacata aaataaatat 11700 aacaaaaaag cacatcttcg ccgtaactca aacgctcatc gattttaacc ttttcaaatt 11760 taaccttttc aaaatttttt aagatgatat cttttctaaa acacttcgcc caaactgacc 11820 agcaaaaatg cctttgtttg cttaagaatt ctaaaaattc tttttgatta aaaactccat 11880 cttgtttaaa acgataaaat tgtttggttt ttaccctatg tacaaaggca tcaaaacaaa 11940 gcaaatcaaa accttttttc atctctttaa acgctatttc acaagcacca ggtgtcaaaa 12000 aatcatcact atctaaaaac attataaaat cagaactaga atgcaaaact cctaaatttc 12060 tacttgcaaa agtgcctaaa ttttcttcat tttgaaagat ttttatcctt ggatcttttt 12120 tagcaaattc taaaaccata tttaaactat tatctttact tttatcatcg ataatcaaaa 12180 tttcaatatc ttttaaagtc tgatttatac aactttgcaa agctcttaag ataaaatcac 12240 aagaattaaa aagcgggatt atgatcgaaa gttgtggcat atttttccta aattttgtta 12300 aaataataaa aacaattcta tcaaagttta ggaaatttat gaaaattttt atacatcttc 12360 ccacctggtt aggcgatacg gtaatggc 12388 // |
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