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EBI DbfetchID AF389475; SV 1; linear; genomic DNA; STD; PRO; 10954 BP. XX AC AF389475; XX DT 29-JAN-2002 (Rel. 70, Created) DT 15-APR-2005 (Rel. 83, Last updated, Version 3) XX DE Streptococcus thermophilus strain SMQ-301 gal-lac operon, partial sequence. XX KW . XX OS Streptococcus thermophilus OC Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus. XX RN [1] RP 1-10954 RX PUBMED; 11790749. RA Vaillancourt K., Moineau S., Frenette M., Lessard C., Vadeboncoeur C.; RT "Galactose and lactose genes from the galactose-positive bacterium RT Streptococcus salivarius and the phylogenetically related RT galactose-negative bacterium Streptococcus thermophilus: organization, RT sequence, transcription, and activity of the gal gene products"; RL J. Bacteriol. 184(3):785-793(2002). XX RN [2] RP 1-10954 RA Vaillancourt K., Moineau S., Frenette M., Lessard C., Vadeboncoeur C.; RT ; RL Submitted (08-JUN-2001) to the EMBL/GenBank/DDBJ databases. RL Department of Biochemistry and Microbiology, GREB, Laval University, RL Ste-Foy, Quebec G1K 7P4, Canada XX FH Key Location/Qualifiers FH FT source 1..10954 FT /organism="Streptococcus thermophilus" FT /strain="SMQ-301" FT /mol_type="genomic DNA" FT /db_xref="taxon:1308" FT terminator complement(15..59) FT /gene="galR" FT /note="hairpin loop" FT /inference="non-experimental evidence, no additional FT details recorded" FT CDS complement(307..1302) FT /codon_start=1 FT /transl_table=11 FT /gene="galR" FT /product="regulator GalR" FT /note="member of GalR-LacI family of transcription FT regulators" FT /db_xref="GOA:Q7BCH1" FT /db_xref="InterPro:IPR000843" FT /db_xref="InterPro:IPR001761" FT /db_xref="InterPro:IPR010982" FT /db_xref="UniProtKB/TrEMBL:Q7BCH1" FT /protein_id="AAL67295.1" FT /translation="MATLADIAKLAGVSISTVSRVLNKDETLSVTEDTRHRILTIADEI FT GYTKYKTINNSKKEKYQVAIIQWVSEEHELDDIYYYNIRLGIEKRAYELDYEMLHFFND FT IPSSLGEEVVGVLCIGKFSREQIAKLERLKKTLVFVDSDTLNQGHPCVTTDFENSVQSA FT LCYLKEQGCNNIGLLIGQEKTTDATEIISDPRLRSYRNYCMEKGIYDPLFILTGDFTVQ FT SGYELLDSKIKSGATLPDAYFAASDSLAIGALRALQENGIKVPDDIQIISFNDTTLAKQ FT VYPPLSSVTVYTEEMGRTAMDILNKQLLAPRKIPTLTKLGTKLTLRNSTK" FT RBS complement(1308..1315) FT /gene="galR" FT /inference="non-experimental evidence, no additional FT details recorded" FT -10_signal complement(1322..1327) FT /gene="galR" FT /inference="non-experimental evidence, no additional FT details recorded" FT -35_signal complement(1346..1351) FT /gene="galR" FT /inference="non-experimental evidence, no additional FT details recorded" FT -35_signal 1379..1384 FT /gene="galK" FT /inference="non-experimental evidence, no additional FT details recorded" FT -10_signal 1402..1407 FT /gene="galK" FT /inference="non-experimental evidence, no additional FT details recorded" FT RBS 1429..1436 FT /gene="galK" FT /inference="non-experimental evidence, no additional FT details recorded" FT CDS 1445..2611 FT /codon_start=1 FT /transl_table=11 FT /gene="galK" FT /product="galactokinase" FT /db_xref="GOA:Q8VS87" FT /db_xref="HSSP:1PIE" FT /db_xref="InterPro:IPR000705" FT /db_xref="InterPro:IPR006203" FT /db_xref="InterPro:IPR006204" FT /db_xref="InterPro:IPR006206" FT /db_xref="InterPro:IPR013750" FT /db_xref="InterPro:IPR014721" FT /db_xref="InterPro:IPR019539" FT /db_xref="InterPro:IPR019741" FT /db_xref="InterPro:IPR020568" FT /db_xref="UniProtKB/TrEMBL:Q8VS87" FT /protein_id="AAL67296.1" FT /translation="MNTSQLREKFKEVFGVEADHTFFSPGRINLIGEHTDYNGGNVLPV FT AITLGTYGAARKRDDKVLRFFSANFEEKGIIEVPLENLRFEKEHNWTNYPKGVLHFLQE FT AGHTIDSGMDIYIYGNIPNGSGLSSSSSLELLIGVIVEKLYDIKLERLDLVKIGKQTEN FT DFIGVNSGIMDQFAIGMGADQCAIYLDTNTLKYDLVPLDLKDNVVVIMNTNKRRELADS FT KYNERRAECETAVSELQEKLDIQTLGELDFLTFDAYSYLIKDENRIKRARHVVLENQRT FT LQARKALEAGDLEGFGRLMNASHVSLEYDYEVTGLELDTLAHTAWEQEGVLGARMTGAG FT FGGCAIALVNKDKVEDFKKAVGQRYEEVVGYAPSFYIAEVTGGSRVLD" FT RBS 2616..2622 FT /gene="galT" FT /inference="non-experimental evidence, no additional FT details recorded" FT CDS 2631..4112 FT /codon_start=1 FT /transl_table=11 FT /gene="galT" FT /product="galactose 1-phosphate uridylyltransferase" FT /db_xref="GOA:Q9ZB09" FT /db_xref="InterPro:IPR000766" FT /db_xref="InterPro:IPR005849" FT /db_xref="InterPro:IPR005850" FT /db_xref="UniProtKB/Swiss-Prot:Q9ZB09" FT /protein_id="AAL67297.1" FT /translation="MAENLVNTFVTQVIENSDYEELDRIYLTNKVFTLVGEGVADVETD FT SSELIDLKDQLLQAGVKAGSVGELNEEQDIIGAQLMDLITPRPSVVNRNFWDTYKSNPE FT QATADFYAQSKRNDYVKVKAIAQNIAYKAPTKYGDLEITINLSKPEKDPKAIAAAKNAV FT ASDYPKCQLCMENEGYLGRINHPARSNHRVVRFQMEDKEWGFQYSPYAYFNEHSIFFYG FT KHEPMHISPLTFGRLLTIVEAFPGYFAGSNADLPIVGGSILTHEHYQGGRHTFPMEVAG FT IKEKVSFDGYSDVEAGIVNWPMSVLRLRSEDKGRLIALATKILNCWRGYSDEKAGVLAE FT SDGQPHHTITPIARRKDGKFELDLVLRDNQTSEEYPDGIYHPHKDVQHIKKENIGLIEV FT MGLAILPPRLKTELKDVEDYLLGQGNQVAPIHQEWADELKAQNPNITAEEVTEVVRQSV FT ADIFARVLEDAGVYKTNSEGLDQFKAFVDFVNLAD" FT RBS 4128..4135 FT /gene="galE" FT /inference="non-experimental evidence, no additional FT details recorded" FT CDS 4142..5143 FT /codon_start=1 FT /transl_table=11 FT /gene="galE" FT /product="UDP-glucose 4-epimerase" FT /db_xref="GOA:Q8VS85" FT /db_xref="HSSP:1GY8" FT /db_xref="InterPro:IPR001509" FT /db_xref="InterPro:IPR005886" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q8VS85" FT /protein_id="AAL67298.1" FT /translation="MAILVLGGAGYIGSHMVDRLVEKGQEKVVVVDSLVTGHRAAVHPD FT AIFYQGDLSDQDFMRKVFKENPDVDAVIHFAAYSLVGESMEKPLKYFDNNTAGMVKLLE FT VMNECGVKYIVFSSTAATYGIPEEIPILETTPQNPINPYGESKLMMETIMKWSDQAYGI FT KYVPLRYFNVAGAKPDGSIGEDHGPETHLLPIILQVAQGVREKIMIFGDDYNTPDGTNV FT RDYVHPFDLADAHLLAVEYLRKGNESTAFNLGSSTGFSNLQILEAARKVTGKEIPAEKA FT DRRPGDPDILIASSEKARTVLGWKPQFDNIEKIIASAWAWHSSHPKGYDDRG" FT -35_signal 5153..5158 FT /gene="galM" FT /inference="non-experimental evidence, no additional FT details recorded" FT terminator 5159..5199 FT /gene="galE" FT /inference="non-experimental evidence, no additional FT details recorded" FT -10_signal 5176..5181 FT /gene="galM" FT /inference="non-experimental evidence, no additional FT details recorded" FT RBS 5196..5205 FT /gene="galM" FT /inference="non-experimental evidence, no additional FT details recorded" FT CDS 5213..6259 FT /codon_start=1 FT /transl_table=11 FT /gene="galM" FT /product="galactose-mutarotase" FT /db_xref="GOA:Q8VS84" FT /db_xref="InterPro:IPR008183" FT /db_xref="InterPro:IPR011013" FT /db_xref="InterPro:IPR013458" FT /db_xref="InterPro:IPR014718" FT /db_xref="InterPro:IPR015443" FT /db_xref="InterPro:IPR018052" FT /db_xref="UniProtKB/TrEMBL:Q8VS84" FT /protein_id="AAL67299.1" FT /translation="MKISCEIIGKVDSGDVSKISMENNNGVVISTLTTGATLQEFLVPT FT ETGALKNIVLGFSDFEDYYKNNLCACQSIGRVAGRIGKASYTHNMVLYSLPKNEGDNCL FT HGGPKGMQVQNWNYVTNLNDDYVETKFIRRLYSSVDGFPGDVTVSISYRLNNNNRLTIL FT FEAFDVTESTVFNPTNHVYFNLSDKQDLSSHELQIYSDYRLELDSELIPTGQKINVDET FT NYDFRKTTDLLPRIEANNGFDDAFVVGGGTCDHVKEVAILHDKESGDGIEIFSNRNGLV FT IFTMDDIEDNIYFARDKGKMAKRREAIAMEAQTLPDAVNHKGFGDIILDKGHSVNYEIG FT FQYFNSSR" FT -35_signal 6300..6305 FT /gene="lacS" FT /inference="non-experimental evidence, no additional FT details recorded" FT -10_signal 6323..6328 FT /gene="lacS" FT /inference="non-experimental evidence, no additional FT details recorded" FT RBS 6346..6353 FT /gene="lacS" FT /inference="non-experimental evidence, no additional FT details recorded" FT CDS 6362..8266 FT /codon_start=1 FT /transl_table=11 FT /gene="lacS" FT /product="lactose transport protein" FT /db_xref="GOA:Q8VS83" FT /db_xref="HSSP:1AX3" FT /db_xref="InterPro:IPR001127" FT /db_xref="InterPro:IPR001927" FT /db_xref="InterPro:IPR011055" FT /db_xref="InterPro:IPR016196" FT /db_xref="InterPro:IPR018043" FT /db_xref="UniProtKB/TrEMBL:Q8VS83" FT /protein_id="AAL67300.1" FT /translation="MEKSKGQMKSRLSYAAGAFGNDVFYATLSTYFIMFVTTHLFNTGD FT PKQNSHYVLLITNIISILRILEVFIDPLIGNMIDNTNTKYGKFKPWVVGGGIISSITLL FT LLFTDLGGLNKTNPFLYLVLFGIIYLVMDVFYSIKDIGFWSMIPALSLDSHEREKMATF FT ARIGSTIGANIVGVAIMPIVLFFSMTNNSGSGDKSGWFWFAFIVALIGVITSIAVGIGT FT REVESKIRDNNEKTSLKQVFKVLGQNDQLMWLSLGYWFYGLGINTLNALQLYYFTFILG FT DSGKYSILYGLNTVVGLVSVSLFPTLADKFNRKRLFYGCIAVMLGGIGIFSIAGTSLPI FT ILTAAELFFIPQPLVFLVVFMIISDSVEYGQWKTGHRDESLTLSVRPLIDKLGGAMSNW FT LVSRFAVAAGMTTGASASTITTHQQFIFKLGMFAFPAATMLIGAFIVARKITLTEARHA FT KIVEELEHRFSVATSENEVKANVVSLVTPTTGYLVDLSSVNDEHFASGSMGKGFAIKPT FT DGAVFAPISGTIRQILPTRHAVGIESEDGVIVLIHVGIGTVKLNGEGFISYVEQGDRVE FT VGQKLLEFWSPIIEKNGLDDTVLVTVTNSEKFSAFHLEQKVGEKVEALSEVITFKKGE" FT RBS 8255..8262 FT /gene="lacZ" FT /inference="non-experimental evidence, no additional FT details recorded" FT CDS 8270..>10954 FT /codon_start=1 FT /transl_table=11 FT /gene="lacZ" FT /product="beta-galactosidase" FT /db_xref="GOA:Q8VS82" FT /db_xref="HSSP:1BGL" FT /db_xref="InterPro:IPR004199" FT /db_xref="InterPro:IPR006101" FT /db_xref="InterPro:IPR006102" FT /db_xref="InterPro:IPR006103" FT /db_xref="InterPro:IPR006104" FT /db_xref="InterPro:IPR008979" FT /db_xref="InterPro:IPR011013" FT /db_xref="InterPro:IPR013781" FT /db_xref="InterPro:IPR013812" FT /db_xref="InterPro:IPR014718" FT /db_xref="InterPro:IPR017853" FT /db_xref="UniProtKB/TrEMBL:Q8VS82" FT /protein_id="AAL67301.1" FT /translation="MNMTEKIQTYLNDPKIVSVNTVDAHSDHKYFESLEEFSEGEMKLR FT QSLNGKWKIHYAQNTNQVLKDFYKTEFDETDLNFINVPGHLELQGFGSPQYVNTQYPWD FT GKEFLRPPQVPQESNAVASYVKHFTLNDALKDKKVFISFQGVATSIFVWVNGNFVGYSE FT DSFTPSEFEISDYLVEGDNKLAVAVYRYSTASWLEDQDFWRLYGIFRDVYLYAIPKVHV FT QDLFVKGDYDYQTKAGQLDIDLKTVGDYEDKKIKYVLSDYEGIVTEGDASVNGDGELSV FT SLENLKIKPWSAESPKLYDLILHVLDDDQVVEVVPVKVGFRRFEIKDKLMLLNGKRIVF FT KGVNRHEFNARTGRCITEEDMLWDIKVMKQHNINAVRTSHYPNQTRWYELCDEYGLYVI FT DEANLETHGTWQKLGLCEPSWNIPASEPEWLPACLDRANNMFQRDKNHASVIIWSCGNE FT SYAGKDIADMADYFRSVDNTRPVHYEGVAWCREFDYITDIESRMYAKPADIEEYLTTGK FT LVDLSSVSDKHFASGNLTNKPQKPYISCEYMHTMGNSGGGLQLYTDLEKYPEYQGGFIW FT DFIDQAIYKTLPNGSEFLSYGGDWHDRPSDYEFCGNGIVFADRTLTPKLQTVKHLYSNI FT KIAVDEKSVTIKNDNLFEDLSAYTFLARVYEDGRKVSESEYHFDVKPGEEATFPVNFVV FT EASNSEQIYEVACVLREATEWAPKGHEIVRGQYVVEKISTETPVKAPLNVVEGDFNIGI FT QGQNFSILLSRAQNTLVSAKYNGVEFIEKGPKLSFTRAYTDNDRGAGYPFEMAGWKVAG FT NYSKVTDTQIQIEDDSVKVTYVHELPGLSDVEVKVTYQVDYKGRIFVTANYDGKAGLPN FT FPEFGLEFAIGSQFTNLNYYGYGA" XX SQ Sequence 10954 BP; 3414 A; 1888 C; 2183 G; 3469 T; 0 other; ctttttaatg gtgaaaaaat aatccatctc actcttgatg aagtaagacg gattattgtt 60 gtttaaatta gtactgtctt ttaaagtgct ttaaaaagag attgagcagg tatagtattt 120 ccttagtatt tgttattcta tgaaaatctc tagtttaaat caatttatgt atgttatttt 180 cctattcagg tttatggttc aaatcgttat ctctaaaaaa ctagatattg gagtaaaagg 240 tatcatttat ctgaatattg taattatgat ctcaaaaccg tagaaaatag tgaagatatg 300 atttacctat tttgtactgt ttcttaatgt taattttgtt cctagtttag taagtgttgg 360 tatttttcga ggtgctaata attgtttatt gagaatatcc atagctgttc gtcccatttc 420 ttctgtatag acagtgacac tagaaagtgg aggatacact tgtttagcta gagttgtatc 480 gttaaaagag ataatttgaa tgtcgtcagg gaccttgata ccattttcct gaagtgctct 540 gagtgcacca atagctagac tatcactagc cgcaaagtaa gcatcaggta aagtagctcc 600 actcttaatc ttagaatcaa gaagttcata gccagattgg acagtgaagt caccagtcag 660 aataaaaaga gggtcataga ttcccttttc catacagtag ttccgataag aacgtaaacg 720 aggatcagag atgatttcag ttgcatctgt tgttttttct tgcccaatga gtaggcctat 780 attattacaa ccttgttctt taagataaca gagtgccgat tgtacggagt tttcaaaatc 840 agtagtaaca catggatgtc cttgattaag agtatcacta tcaacaaaga ccagagtctt 900 ttttagtctt tctagtttcg caatttgttc acgactaaat tttccgatac atagtacacc 960 aacgacctcc tctcctagac ttgaaggaat gtcgttgaaa aagtgaagca tctcgtagtc 1020 tagttcatag gctctttttt caataccaag tctaatatta taatagtaga tgtcatctaa 1080 ctcgtgttct tcactaaccc attgaataat tgccacttga tacttttctt tttttgaatt 1140 attaattgtt ttgtatttag tatatccgat ttcatcagcg atagttaata tccgatgtct 1200 agtatcctct gttacggaaa gagtttcatc tttattaaga acacgtgaaa cagttgaaat 1260 agatacacct gctaattttg cgatatctgc taatgtagcc atagtatcct cctcatattt 1320 cagtataaca taacttttat ttttttacct atattttact aaaaaaatag taaaaatatt 1380 gattttccat gtgaaagggg ttacgatttc agtataaaca aaaagaataa gtgagataca 1440 tcctatgaat acatcacagt taagagaaaa gtttaaagaa gtttttggtg tagaagcaga 1500 tcatactttc ttttcaccag gtcgtattaa tttgattggt gagcatacgg actacaatgg 1560 aggtaacgtc cttccggtag ctattaccct aggtacttac ggagcggccc gcaaacgtga 1620 tgacaaagtt ttgcgtttct tctcagctaa ctttgaagag aagggaatca tcgaagtgcc 1680 acttgaaaat cttcgttttg aaaaagaaca caactggaca aactatccaa aaggtgttct 1740 tcatttcttg caagaagctg ggcatacgat tgattcaggt atggatattt acatctatgg 1800 taacattcca aacggatcag gcttgtcatc atcatcatct ttggaattat tgattggtgt 1860 tattgttgaa aaactttatg acattaaatt ggaacgcctg gacttggtta aaatcggaaa 1920 acaaacggaa aatgacttta tcggcgttaa ctctggtatc atggaccaat tcgctattgg 1980 tatgggagct gatcaatgtg cgatttactt ggacacaaat actctaaagt atgacttggt 2040 accccttgac ctcaaggata atgtcgtagt catcatgaac actaacaaac gtcgtgaatt 2100 ggctgattct aaatacaatg aacgtcgtgc tgaatgtgaa acagcagtat ctgaactaca 2160 agaaaaattg gatatccaaa ctctcggtga attagacttc ttgacatttg acgcatacag 2220 ctatttgatt aaagatgaaa accgtatcaa acgtgcacgc catgtagttc ttgaaaatca 2280 acgtacactt caagctcgta aagctcttga agcaggagat ttggaaggct ttggacgcct 2340 tatgaatgct tctcatgtgt cattggaata tgattacgaa gttacaggtc ttgaacttga 2400 tactttggca cacacagctt gggaacaaga aggagtatta ggagcccgca tgacaggagc 2460 tggtttcggt ggatgtgcca ttgcacttgt aaacaaagac aaagttgaag acttcaaaaa 2520 agcagttggt caacgctatg aagaagtcgt tggttatgca ccaagcttct atattgccga 2580 agtaactggt ggttcacgag tacttgatta atgagaaaga agtagagatt atggctgaaa 2640 atttagtaaa cacttttgta actcaggtta ttgaaaatag tgattatgag gaattggacc 2700 gtatctattt gacaaacaaa gtttttactt tggttggaga aggagttgct gatgttgaaa 2760 cagatagctc tgaattgatt gaccttaaag accagttgct tcaagcaggt gttaaagctg 2820 gttccgtagg tgaacttaac gaagaacaag atatcatcgg tgctcaactc atggacttaa 2880 ttacaccaag accgagcgtt gtcaatcgta acttctggga tacttataaa tctaacccag 2940 agcaagcaac tgctgacttt tatgcacaaa gtaaacgaaa tgattatgtg aaagtcaaag 3000 ccattgcaca aaatattgct tataaagcac caactaaata cggtgacttg gaaattacga 3060 ttaacctttc aaaacctgaa aaagatccca aagccatcgc tgcagctaaa aatgcggtag 3120 cttctgatta tccaaaatgc caactttgta tggaaaatga aggttatttg ggtcgcatta 3180 atcacccagc ccgcagcaat caccgtgttg ttcgtttcca aatggaagac aaggagtggg 3240 gcttccaata ctcgccttat gcctacttta acgaacattc tatcttcttt tatggtaagc 3300 acgaaccaat gcacatcagt ccattgacgt ttggccgtct cctaacaatt gttgaagcat 3360 tccctggtta cttcgcaggt tcaaatgccg atcttccaat tgtaggtggt tcaattctta 3420 cacatgaaca ctatcaaggt ggtcgccata ccttcccaat ggaagtagca ggcattaaag 3480 aaaaagttag ctttgatggt tactctgatg ttgaggctgg catcgttaat tggcctatgt 3540 ctgttcttcg tctaagaagt gaagacaagg gaagacttat cgctcttgca actaaaatcc 3600 taaattgctg gcgtggttat tcagacgaaa aagctggggt cttggctgag tctgatggac 3660 aacctcacca caccattact ccaattgctc gtagaaaaga cggcaaattt gaattggatt 3720 tggttcttcg tgacaatcaa acttctgaag aatatccaga cggtatctat cacccacata 3780 aagatgttca acatattaag aaagaaaata ttggtttgat tgaagttatg ggattggcca 3840 ttcttccacc tcgtttgaaa acagaactta aagatgttga agattatcta ttaggtcaag 3900 gtaaccaagt tgctccaatt caccaagaat gggcagatga actcaaagct caaaatccga 3960 atattacggc tgaggaagtg acagaagttg ttcgacaatc tgttgcagat atctttgctc 4020 gtgtactaga agatgcaggt gtttataaga ctaatagtga aggcttggat cagtttaaag 4080 catttgtaga ttttgtaaat ttagctgatt aattgttttt tctgaagaaa ggagataaaa 4140 aatggcaatt ttagtattag gtggagctgg ttatatcggt tctcacatgg ttgatcgctt 4200 agttgaaaaa ggtcaagaaa aagtagtagt agtagatagt ttggtaacag gtcaccgtgc 4260 tgccgtacat ccagatgcta ttttttatca aggcgatctt tctgatcagg attttatgag 4320 aaaggtcttc aaagaaaacc ctgatgttga tgctgttatt cactttgcgg cctattcttt 4380 ggttggtgaa tcaatggaaa aaccactcaa atattttgat aacaacacag ctggaatggt 4440 taaattgctt gaggttatga acgaatgtgg tgttaaatac attgtcttct catcaacagc 4500 agcaacttac ggaattccag aagaaattcc aattcttgaa acaacaccac aaaatcctat 4560 caacccatat ggtgaaagta agttgatgat ggaaaccatt atgaagtggt cagaccaagc 4620 ttacggcatc aagtatgtcc ctcttcgtta ctttaatgtg gcgggtgcca aacctgatgg 4680 ttcgattggt gaggaccacg gtccagaaac tcaccttcta ccgattattc ttcaagtagc 4740 tcaaggtgtt cgtgaaaaaa tcatgatctt tggggatgac tacaatactc cagacgggac 4800 taacgttcgt gactatgtgc atccattcga cttggcggac gctcacctcc ttgctgttga 4860 atatcttcgt aaaggtaatg aatctacagc ctttaactta ggttcatcaa caggtttctc 4920 aaaccttcaa attcttgaag cagctcgtaa ggtaactggt aaagagattc cagctgaaaa 4980 agctgatcgt cgtcctggtg atcctgatat attgattgct tcatctgaaa aagcacgtac 5040 agttcttgga tggaaaccac aatttgataa catcgaaaaa atcatcgcaa gtgcttgggc 5100 atggcattct agccatccaa aagggtacga tgatcgagga taattaaaat aataaacaaa 5160 aaaacaaaga gtatatataa ttgttgtact ctttgttttt tgaggaaata atatgaaaat 5220 aagctgcgaa attattggaa aagttgattc aggcgatgtc agtaaaattt caatggaaaa 5280 taataatggt gttgtcattt ccacactcac aacaggtgct acacttcagg agtttttggt 5340 tccaacggaa actggtgctc ttaaaaatat agtacttggt ttcagtgatt tcgaggatta 5400 ctataagaat aatttatgtg cctgccagtc cattggtagg gttgctggaa gaattgggaa 5460 agcttcgtat actcataata tggttcttta tagccttcct aagaatgagg gagacaactg 5520 cttacatggc ggtccaaaag gaatgcaggt tcaaaattgg aactatgtca caaacctgaa 5580 tgatgattat gttgagacaa aatttattag aagactttat tcaagtgtag atggctttcc 5640 tggtgatgtg acagtctcta ttagttatag acttaacaat aataaccgct taacaatact 5700 ctttgaagcc ttcgatgtta cagagtcaac agtctttaat ccgacaaacc atgtttactt 5760 taatcttagc gacaaacagg atttatcaag tcatgagtta caaatctatt cagactatcg 5820 tttagagttg gattctgagt taattccaac aggacaaaaa attaatgtag atgaaacgaa 5880 ttatgatttt agaaagacaa ctgacttgct acctcgaatt gaagcaaata atggttttga 5940 tgatgccttt gtagttggag ggggaacttg tgatcatgtg aaagaagtag ctattttgca 6000 tgacaaagaa agtggagatg gtattgaaat cttctcaaac agaaatggtt tagtcatttt 6060 tacgatggat gatatcgaag ataatattta ctttgcaaga gataaaggca aaatggcaaa 6120 aaggcgtgaa gctattgcta tggaagctca aacccttcca gatgccgtta atcacaaagg 6180 ttttggagat attatcttag ataaaggtca tagtgtaaac tatgaaattg gcttccaata 6240 ctttaattca tcaagataac catgtattag taaaatttta gtaaaaaaca ctgaaattat 6300 tgactgcata aaccaatttt catataatgt aaacgtattc aaataatagg aggtttccga 6360 aatggaaaaa tctaaaggtc agatgaagtc tcgtttatcc tacgcagctg gtgcttttgg 6420 taacgacgtc ttctatgcaa ccttgtcaac atactttatc atgtttgtga caactcactt 6480 gtttaacaca ggtgatccaa agcaaaatag tcactacgta ctattaatca ctaacattat 6540 ctctattttg cgtatcttgg aagtatttat cgatccattg atcggtaata tgattgataa 6600 cactaatact aagtatggta aattcaaacc atgggtagtt ggtggtggta tcatcagttc 6660 tatcaccttg ttgcttctct tcaccgattt aggtggtttg aataaaacaa atcctttctt 6720 gtaccttgta ctttttggaa ttatctacct tgtaatggat gtcttctact cgattaaaga 6780 tatcggtttc tggtcaatga ttcctgcctt gtctcttgat agtcacgaac gtgaaaaaat 6840 ggcaactttt gcccgtattg gttctacgat tggtgccaat attgtaggtg ttgccatcat 6900 gccaatcgtt ttgttcttct ctatgacgaa caatagtggc tctggagata aatctggatg 6960 gttctggttt gcatttatcg ttgctctcat tggtgtaatt acatcaattg ctgttggtat 7020 tggtacacgt gaagttgagt caaaaattcg tgataataac gaaaaaacta gccttaaaca 7080 agtctttaag gttcttggtc aaaacgacca attgatgtgg ttatctcttg gatattggtt 7140 ctatggtctt ggtattaata cacttaatgc tcttcaactt tattatttca catttatcct 7200 tggtgattca ggtaaatact caattcttta cggattgaat acagttgttg gtttggtttc 7260 agtttcactc ttccctaccc tagctgataa attcaaccgt aaacgtttgt tctacggatg 7320 tattgcagta atgctcgggg gtatcggaat atttagtatt gcaggtacat cacttccaat 7380 aatcttgact gcagctgaac tcttcttcat tccacaacct cttgtgttcc ttgttgtctt 7440 tatgattatc tctgactcag tagaatatgg tcaatggaaa acgggacacc gtgatgaatc 7500 acttactttg tcagttcgtc cacttattga taaacttggt ggtgcgatgt caaactggct 7560 tgtttctaga tttgccgtag ctgccggtat gacaacaggt gcctcagcat caacaattac 7620 aacacatcaa cagtttatct ttaagcttgg catgtttgct ttcccagcag caacaatgct 7680 tatcggtgcc ttcattgttg ctcgtaaaat cactttgact gaagcacgtc acgctaaaat 7740 tgttgaagaa ttggaacatc gctttagcgt agcaacttct gaaaatgaag ttaaagctaa 7800 cgtcgtatct cttgtaaccc ctacaactgg ttatttggtt gatctctcaa gtgttaatga 7860 tgaacacttt gcttcaggta gcatgggtaa aggtttcgcc attaaaccta ctgatggagc 7920 tgtctttgca ccaattagtg gtaccattcg tcaaattctt cctactcgcc atgcagttgg 7980 tattgaaagt gaagatggtg tcattgttct tatccacgtt ggcatcggaa cagttaaact 8040 taatggtgaa ggattcatta gttacgtaga acaaggtgat cgtgttgaag ttggacaaaa 8100 acttcttgag ttctggtcac caattattga gaaaaatggt cttgatgaca cagtacttgt 8160 cactgtaact aattcagaaa aattcagtgc tttccatctt gaacaaaaag ttggagaaaa 8220 ggtagaagct ttgtctgaag ttattacctt caaaaaagga gaataatcta tgaacatgac 8280 tgaaaaaatt caaacttatt taaacgatcc aaagattgtt agcgttaata ctgttgatgc 8340 tcactcagat cataagtatt ttgaatctct tgaagaattt tctgaagggg agatgaagtt 8400 aagacaatct cttaatggaa aatggaaaat tcactatgct cagaatacaa atcaggtttt 8460 aaaagacttt tataaaacag aatttgatga aactgatttg aatttcatca atgtaccagg 8520 tcatttagag cttcaaggtt ttggttctcc acaatatgtg aatacccaat atccttggga 8580 tggtaaagaa ttccttcgtc cacctcaagt tcctcaagaa tcaaatgctg ttgcatcata 8640 cgttaaacat tttaccttga atgatgcatt aaaagataaa aaagtattta tctcattcca 8700 aggggttgct acttccatct ttgtatgggt caatggtaac ttcgtaggat acagtgaaga 8760 ttcatttaca cctagtgaat ttgaaattag tgattacctt gttgaaggtg ataacaagtt 8820 ggcggtagct gtttatcgtt actctacagc aagctggttg gaagaccaag acttctggag 8880 actttacggt atttttagag atgtttactt gtatgctatt ccaaaagttc acgttcaaga 8940 tctctttgtt aagggagatt atgattacca aacaaaagca ggtcaattgg atattgattt 9000 gaagactgtt ggtgattatg aagacaagaa gattaaatat gttctttcag attatgaagg 9060 catcgttaca gaaggtgatg catctgttaa tggtgacggt gaactatctg taagtcttga 9120 aaatcttaaa atcaaacctt ggagtgctga aagtcctaaa ctttacgatt tgatccttca 9180 tgttttggat gatgaccaag ttgttgaagt cgttccagtt aaagttggat tcagacgctt 9240 tgaaattaaa gataaactta tgcttttgaa tggtaagaga attgtcttta aaggggttaa 9300 cagacacgaa tttaacgcta gaacaggacg ttgtatcact gaagaagata tgctttggga 9360 tatcaaagtg atgaagcaac ataacatcaa tgctgttcgt acttcacact atcctaacca 9420 aacacgttgg tatgaattgt gtgatgaata tggactttat gttatcgatg aagccaacct 9480 tgaaacacac ggtacatggc aaaaacttgg tctatgcgaa ccttcatgga atatcccagc 9540 tagtgaacca gaatggttgc ctgcttgttt ggatcgtgcc aataacatgt tccaacgcga 9600 taagaaccac gctagtgtta tcatttggtc ttgtggtaat gaatcatatg ctggtaaaga 9660 tattgctgac atggctgatt acttccgtag tgttgacaat actcgtccag ttcactatga 9720 aggtgttgca tggtgtcgtg agtttgatta cattacagac atcgaaagtc gtatgtatgc 9780 gaaaccagct gatatcgaag aatacctcac aactggtaaa ctagttgatc tttcaagcgt 9840 tagtgataaa cactttgctt caggtaacct aactaacaaa cctcaaaaac cttatatttc 9900 atgtgaatac atgcacacaa tgggtaactc tggtggtgga ttgcaactct acactgactt 9960 agagaaatat ccagaatacc aaggtggatt tatttgggac ttcattgacc aagctattta 10020 caaaacactt ccaaatggta gcgaattcct atcatatggt ggtgactggc atgatagacc 10080 ttctgactac gaattttgtg gaaatggtat cgtctttgca gatcgtaccc taactccaaa 10140 acttcaaaca gttaaacatc tttactctaa tattaagatt gctgttgatg aaaaatcagt 10200 aactatcaag aatgataatc tcttcgaaga tctttctgct tatactttcc tagctagagt 10260 ttacgaagat ggtagaaaag ttagtgaaag tgaatatcac tttgatgtta aaccaggcga 10320 agaagcaaca ttcccagtta actttgtagt cgaggcttca aattctgaac aaatttacga 10380 agttgcttgt gttctgaggg aagcaactga atgggctcct aaaggtcatg aaattgttcg 10440 tggtcaatat gttgttgaaa agattagcac tgaaacacca gttaaagcac ctttgaatgt 10500 tgttgaaggc gacttcaaca tcggtattca aggacaaaac ttctcaatct tgctttcacg 10560 tgcacaaaat actttagtat ctgctaagta taatggtgtt gaattcattg agaaaggtcc 10620 taaacttagc ttcactcgtg cttacactga caacgatcgt ggtgctggat atccattcga 10680 aatggcaggc tggaaggttg ctggaaacta tagtaaagtt acagatactc aaattcaaat 10740 cgaagacgac tctgttaaag tgacttatgt tcatgaattg ccaggcttgt ctgatgtcga 10800 agttaaggta acttatcaag ttgattacaa gggtcgaatc tttgttactg caaactatga 10860 tggtaaagca ggtttgccaa acttccctga atttggtcta gaatttgcta tcggttcaca 10920 atttacaaac cttaactatt atggatacgg tgca 10954 // |
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