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EBI DbfetchID AF378003; SV 1; linear; mRNA; STD; VRL; 3915 BP. XX AC AF378003; XX DT 31-MAY-2001 (Rel. 67, Created) DT 17-MAR-2002 (Rel. 71, Last updated, Version 2) XX DE Mammalian orthoreovirus 1 Lang core-spike protein lambda-2 (L2) mRNA, DE complete cds. XX KW . XX OS Mammalian orthoreovirus 1 Lang OC Viruses; dsRNA viruses; Reoviridae; Spinareovirinae; Orthoreovirus. XX RN [1] RP 1-3915 RX DOI; 10.1006/viro.2001.1052 RX PUBMED; 11531411. RA Breun L.A., Broering T.J., McCutcheon A.M., Harrison S.J., Luongo C.L., RA Nibert M.L.; RT "Mammalian reovirus L2 gene and lambda2 core spike protein sequences and RT whole-genome comparisons of reoviruses type 1 Lang, type 2 Jones, and type RT 3 Dearing"; RL Virology 287(2):333-348(2001). XX RN [2] RP 1-3915 RA Breun L.A., Broering T.J., McCutcheon A.M., Harrison S.J., Luongo C.L., RA Nibert M.L.; RT ; RL Submitted (08-MAY-2001) to the EMBL/GenBank/DDBJ databases. RL Department of Microbiology and Molecular Genetics, Harvard Medical School, RL 200 Longwood Avenue, Boston, MA 02115, USA XX FH Key Location/Qualifiers FH FT source 1..3915 FT /organism="Mammalian orthoreovirus 1 Lang" FT /strain="Lang" FT /isolate="T1/Human/Ohio/1953" FT /serotype="1" FT /mol_type="mRNA" FT /note="core-transcribed mRNA" FT /db_xref="taxon:10884" FT primer_bind 1..2 FT /gene="L2" FT CDS 13..3882 FT /codon_start=1 FT /gene="L2" FT /product="core-spike protein lambda-2" FT /function="guanylyltransferase, 7-N-methyltransferase and FT 2'-0-methyltransferase in reovirus mRNA 5' capping" FT /note="pentameric in virus particles" FT /db_xref="GOA:Q91RA6" FT /db_xref="HSSP:1EJ6" FT /db_xref="InterPro:IPR010311" FT /db_xref="UniProtKB/Swiss-Prot:Q91RA6" FT /protein_id="AAK57507.1" FT /translation="MANVWGVRLADSLSSPTIETRTRHYTLRDFCSDLDAVAGKEPWRP FT LRNQRTNDIVAVQLFRPLQGLVLDTQFYGFPGIFSEWEQFIKEKLRVLKYEVLRIYPIS FT NYNHERVNVFVANALVGAFLSNQAFYDLLPLLVINDTMINDLLGTGAALSQFFQSHGEV FT LEVAAGRKYLQMKNYSNDDDDPPLFAKDLSDYAKAFYSDTFETLDRFFWTHDSSAGVLV FT HYDKPTNGNHYILGTLTQMVSAPPHIINATDALLLESCLEQFAANVRARPAQPVARLDQ FT CYHLRWGAQYVGEDSLTYRLGVLSLLATNGYQLARPIPKQLTNRWLSSFVSQVMSDGVN FT ETPLWPQERYVQIAYDSPSVVDGATHYGYVRRNQLRLGMRVSALQSLSDTPAPIQWLPQ FT YTIEQAAVDEGDLMVSRLTQLPLRPDYGSIWVGDALSYYVDYNRSHRVVLSSELPQLPD FT TYFDGDEQYGRSLFSLARKIGDRSLIKDTAVLKHAYQAIDPNTGKEYLRAGQSVAYFGA FT SAGHSGADQPLVIEPWTQGKISGVPPPSSVRQFGYDVAKGAIVDLARPFPSGDYQFVYS FT DVDQVVDGHDDLSISSGLVESLLDSCMHATSPGGSFVMKINFPTRTVWHYIEQKILPNI FT TSYMLIKPFVTNNVELFFVAFGVHQQSALTWTSGVYFFLVDHFYRYETLSTISRQLPSF FT GYVDDGSSVTGIEMISLENPGFSNMTQAARVGISGLCANVGNARKLISIHESHGARVLT FT ITSRRSPASARRKARLRYLPLVDPRSLEVQARTILPSNPVLFDNVNGASPHVCLTMMYN FT FEVSSAVYDGDVVLDLGTGPEAKILELIPPTSPVTCVDIRPTAQPSGCWNVRTTFLELD FT YLSDGWITGIRGDIVTCMLSLGAAAAGKSMTFDAAFQQLVKVLTKSTANVLLIQVNCPT FT DVIRTIKGYLEIDQTNKRYRFPKFGRDEPYSDMDSLERICRAAWPNCSITWVPLSYDLR FT WTKLALLESTTLSSASVRIAELMYKYMPVMRIDIHGLPMEKQGNFIVGQNCSLTIPGFN FT AQDVFNCYFNSALAFSTEDVNSAMIPQVTAQFDANKGEWSLDMVFSDAGIYTMQALVGS FT NANPVSLGSFVVDSPDVDITDAWPAQLDFTIAGTDVDITVNPYYRLMAFVRIDGQWQIA FT NPDKFQFFSSSTGTLVMNVKLDIADRYLLYYIRDVQSRDVGFYIQHPLQLLNTITLPTN FT EDLFLSAPDMREWAVKESGNTICILNSQGFVPPQDWDVLTDTISWSPSLPTYVVPPGDY FT TLTPL" FT primer_bind complement(3912..3915) FT /gene="L2" XX SQ Sequence 3915 BP; 986 A; 868 C; 954 G; 1107 T; 0 other; gctattggcg caatggcgaa cgtttgggga gtgagacttg cagactcttt atcatcaccc 60 actattgaga caagaactcg tcattacaca ctacgcgatt tctgttccga cctggatgct 120 gtggctggca aggaaccctg gagacctttg cgcaatcaga gaacgaatga cattgtcgcc 180 gttcaattgt ttaggccact gcagggattg gtgcttgaca cgcagttcta tggattccct 240 ggcattttct cagaatggga gcagtttata aaggaaaaac tccgcgtatt aaaatatgag 300 gttttgcgga tctacccaat cagtaattat aatcatgaac gtgtcaatgt cttcgtagca 360 aatgctcttg tcggtgcgtt cctatccaac caagccttct atgacctgtt gcctctatta 420 gtaataaatg ataccatgat aaatgactta cttgggacag gtgccgccct ttctcaattt 480 tttcaatccc atggtgaggt tttagaagtt gccgcaggaa ggaagtacct gcaaatgaag 540 aactactcga acgatgacga tgatccacct ttgttcgcta aagatctgtc ggactatgcg 600 aaggcgtttt acagtgacac gtttgagact ctagaccgat ttttctggac acatgactca 660 tctgcgggcg tcctagtgca ctatgataag cccactaacg ggaatcatta catcttgggt 720 actctgacgc agatggttag tgcgcctccg catatcatta acgctactga cgcattgttg 780 ctcgaatcgt gcttagaaca atttgcggcg aatgtgagag ccaggccagc gcagcctgtt 840 gcgagattgg atcaatgtta tcatttacgg tggggtgctc aatatgttgg cgaggactca 900 ttgacgtacc gtttgggggt actttcgctg ctggctacca acggatatca attagctaga 960 ccgatcccta agcaattgac gaatcgatgg ctctctagtt ttgtcagtca ggtaatgtcg 1020 gatggtgtaa atgagacgcc attatggcct caagagagat atgtccaaat agcctacgat 1080 tcaccatctg tagtcgatgg agccacgcac tatggctatg ttaggcgaaa tcagttgcgg 1140 ttgggcatga gggtgtccgc tcttcagtca ttgagtgata ctccggctcc gatacagtgg 1200 ttaccgcagt atactattga acaggcagct gttgatgagg gagatctaat ggtttctcgc 1260 ttgactcaac taccattacg tcctgactat ggcagcatat gggttggtga tgccctatcg 1320 tattatgttg attacaatcg cagccataga gttgtactat catccgaact accacagcta 1380 ccagatacat actttgacgg agatgagcaa tacggtcgta gcttgttctc tctagcacga 1440 aaaattggtg atcgatctct catcaaagat acagcagtgc ttaagcatgc gtaccaggcc 1500 attgatccaa acactggaaa ggaatacctt cgcgcaggac agtccgttgc atactttggg 1560 gcatcagctg gtcattcagg ggcggatcag cctctagtaa ttgagccatg gacgcagggt 1620 aagattagtg gtgtgcctcc gccctcctca gttagacagt ttgggtatga tgttgctaaa 1680 ggtgcgatcg tagacttagc aagaccgttc ccgtcgggcg actaccaatt tgtatattct 1740 gacgtcgatc aggtcgttga tggccacgat gatctcagca tatcctcagg actggtggag 1800 agtctattag actcatgcat gcatgccaca tccccaggtg ggtcattcgt gatgaagatc 1860 aacttcccga cacgcactgt ctggcactat atagagcaga agattctccc aaatattacc 1920 tcgtacatgt tgattaaacc attcgtgact aataatgtag agttattctt tgtggctttt 1980 ggtgtgcatc aacaatcagc attgacatgg acgtctgggg tgtatttctt cctggtcgat 2040 cacttctatc gatacgagac attgtctacg atttcacgtc agttgccatc gttcggatac 2100 gttgatgatg ggtcgtctgt gacaggcatt gagatgatca gtcttgaaaa tccaggcttt 2160 tcaaacatga cccaagctgc acgtgttggg atatcagggt tgtgtgcgaa tgtcggtaat 2220 gcgcgtaaat taatatctat tcatgaatcc catggggcac gcgtgctcac catcacatca 2280 agaagatctc cagcttcggc caggcggaaa gctcgcttac gctatttgcc actcgtagac 2340 ccacgatctt tggaagtgca ggcacgtacg atactgccat ctaacccagt gttgtttgat 2400 aacgtaaacg gagcatcgcc tcacgtatgt ttgacgatga tgtataactt tgaagtgtct 2460 agtgcggtgt atgatggtga tgtagtactt gatcttggta ccggtcctga agcgaagatt 2520 ctggagctga ttcctccaac atccccggta acatgcgtag acattaggcc aacggcacag 2580 ccgagtggct gttggaacgt acgtacgact tttctagagc ttgattactt aagtgacggt 2640 tggataacgg gtatacgtgg cgacatcgtc acttgcatgc tgtctctggg tgctgctgct 2700 gctggaaaat ccatgacgtt cgacgcggca ttccaacagc tagtgaaagt tcttactaaa 2760 agtacagcta acgtgttgtt gattcaagtc aactgcccaa cggatgtgat ccgaacaatt 2820 aagggatatt tggagataga tcaaactaat aagcggtaca gatttccaaa gtttggccgc 2880 gatgaaccgt actctgacat ggattcatta gagcgcatat gtcgggctgc atggccaaat 2940 tgttccatca cgtgggtgcc cttgtcctat gacctgcgtt ggactaagct tgctctactt 3000 gaatcgacta cactgagcag tgcatcagtg agaattgctg aattgatgta caagtacatg 3060 cccgttatga ggatagatat tcatgggtta cccatggaaa agcaaggcaa tttcatagtg 3120 ggtcagaact gctctttgac tataccgggc ttcaacgcac aggacgtatt caattgttac 3180 ttcaactccg cgctcgcctt ctctactgag gatgttaatt ctgcaatgat accacaggtg 3240 acggctcagt ttgatgctaa caaaggagag tggtcattgg acatggtgtt ctcagacgct 3300 ggtatctaca caatgcaggc attggtcggt tccaacgcaa atcctgtgtc tctgggttcg 3360 tttgtagtgg actctccgga tgtggacata acagatgcat ggcctgctca gctggacttt 3420 accatagctg gcactgacgt cgacattaca gttaatcctt attaccgctt gatggccttt 3480 gtgaggattg atggacaatg gcagattgcg aatcctgata aattccaatt tttctcatca 3540 agtacaggaa cgttagtgat gaatgtaaag ttagatatag ctgataggta cttgttatac 3600 tacattcgtg acgttcaatc tagggatgtg ggattttaca tacagcaccc attacagtta 3660 ttaaatacta ttacgctgcc tacaaatgag gacttattct tgagcgctcc tgacatgcgc 3720 gagtgggcag taaaggagag tggtaatacc atatgcatac ttaatagtca aggttttgtg 3780 ccacctcagg attgggatgt tcttaccgat actattagct ggtctccttc gctcccaact 3840 tatgtggtgc ctccgggtga ttatactctg acacctctgt aactcattac ccctcgtgag 3900 cgtgcctaat tcatc 3915 // |
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