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EBI DbfetchID AF257460; SV 1; linear; genomic DNA; STD; PRO; 4668 BP. XX AC AF257460; XX DT 05-DEC-2000 (Rel. 66, Created) DT 05-DEC-2000 (Rel. 66, Last updated, Version 1) XX DE Campylobacter jejuni 2,3-sialyl transferase (cstIII), putative sialic acid DE synthase (neuB1), N-acetyl mannosamine synthesis protein (neuC1), and beta DE 1,4-N-acetylgalalactosaminyltransferase/ CMP-NeuNAc synthetase fusion DE protein (cgt/neuA1 fusion) genes, complete cds. XX KW . XX OS Campylobacter jejuni OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; OC Campylobacteraceae; Campylobacter. XX RN [1] RP 1-4668 RX DOI; 10.1128/IAI.68.12.6656-6662.2000 RX PUBMED; 11083778. RA Guerry P., Ewing C.P., Hickey T.E., Prendergast M.M., Moran A.P.; RT "Sialylation of lipooligosaccharide cores affects immunogenicity and serum RT resistance of Campylobacter jejuni"; RL Infect. Immun. 68(12):6656-6662(2000). XX RN [2] RP 1-4668 RA Guerry P., Ewing C.P.; RT ; RL Submitted (18-APR-2000) to the EMBL/GenBank/DDBJ databases. RL Enteric Diseases, Naval Medical Research Center, 503 Robert Grant Ave., RL Silver Spring, MD 20910, USA XX FH Key Location/Qualifiers FH FT source 1..4668 FT /organism="Campylobacter jejuni" FT /strain="MSC 57360" FT /serotype="HS01" FT /mol_type="genomic DNA" FT /note="type strain of HS01 serotype" FT /db_xref="taxon:197" FT CDS 53..937 FT /codon_start=1 FT /transl_table=11 FT /gene="cstIII" FT /product="2,3-sialyl transferase" FT /note="Cst; involved in sialylation of LOS core" FT /db_xref="GOA:Q7BP25" FT /db_xref="InterPro:IPR009251" FT /db_xref="UniProtKB/TrEMBL:Q7BP25" FT /protein_id="AAG37020.1" FT /translation="MSMNINALVCGNGPSLKNIDYKRLPKQFDVFRCNQFYFEDRYFVG FT KDVKYVFFNPFVFFEQYYTSKKLIQNEEYNIENIVCSTINLEYIDGFQFVDNFELYFSD FT AFLGHEIIKKLKDFFAYIKYNEIYNRQRITSGVYMCATAVALGYKSIYISGIDFYQDTN FT NLYAFDNNKKNLLNKCTGFKNQKFKFINHSMACDLQALDYLMKRYDVNIYSLNSDEYFK FT LAPDIGSDFVLSKKPKKYINDILIPDKYAQERYYGKKSRLKENLHYKLIKDLIRLPSDI FT KHYLKEKYANKNR" FT CDS 918..1949 FT /codon_start=1 FT /transl_table=11 FT /gene="neuB1" FT /product="putative sialic acid synthase" FT /note="NeuB1" FT /db_xref="GOA:Q9EU02" FT /db_xref="InterPro:IPR006190" FT /db_xref="InterPro:IPR013132" FT /db_xref="InterPro:IPR013785" FT /db_xref="InterPro:IPR013974" FT /db_xref="InterPro:IPR020007" FT /db_xref="UniProtKB/TrEMBL:Q9EU02" FT /inference="non-experimental evidence, no additional FT details recorded" FT /protein_id="AAG37021.1" FT /translation="MQIKIDKLTISQKNPLIIPEIGINHNGSLEIAKLMVDAAKRAGAK FT IIKHQTHIVEDEMSQEAKNVIPGNANISIYEIMEQCALNYKDELALKEYVEKQGLVYLS FT TPFSRAAANRLEDMGVSAYKIGSGECNNYPLIKHIAQFKKPMIISTGMNSIESIKPTVK FT ILRDYEIPFVLLHTTNLYPTPSHLVRLQAMLELYKEFNCLYGLSDHTTNNLACIGAIAL FT GASVLERHFTESMDRKGPDIVCSMDESTLKDLINQTQEMVLLRGDNNKNPLKEEQVTID FT FAFASVVSIKDIKKGEILSMDNIWVKRPSKGGISAKDFEAILGKRAKKDIKNNIQLTWD FT DFE" FT CDS 1946..3061 FT /codon_start=1 FT /transl_table=11 FT /gene="neuC1" FT /product="N-acetyl mannosamine synthesis protein" FT /note="NeuC1" FT /db_xref="GOA:Q7BP23" FT /db_xref="InterPro:IPR003331" FT /db_xref="InterPro:IPR020004" FT /db_xref="UniProtKB/TrEMBL:Q7BP23" FT /protein_id="AAG37022.1" FT /translation="MKKIVFVSGTRADFSKIKSLMMKVENSNEFELFIFVTGMHMSKKF FT GSTYMEIEKCGFKNIYKYINHDKYYQMDKALSSTIDGFSKFIHEIEPDLIVVHGDRVEP FT LAAAIVGSLNNILVAHIEGGELSGTIDESLRHAISKLAHIHLVNDEIAKKRLIQMGEDE FT KSIFIIGSPDLELLNNTISLDEAKKYYDIKFKNYAIAIFHPITTEINSLYKQSEEFVNA FT LIKSEKNYIVIYPNNDLGFELILQNYERLKNNERFKIFPSLRFEYFISLLKNANFIIGN FT SSCIIKEALYLNINGILVGSRQDGRTDINKTIRVNAEEKDILEAILNTSKCTNITNKRL FT EILNSSEQFYRLLKNNILFTINKQKIFMDKK" FT CDS 3058..4668 FT /codon_start=1 FT /transl_table=11 FT /gene="cgt/neuA1 fusion" FT /product="beta 1,4-N-acetylgalalactosaminyltransferase/ FT CMP-NeuNAc synthetase fusion protein" FT /note="Cgt/NeuA1; apparent fusion of beta FT 1,4-N-acetylgalalactosaminyltransferase and CMP-NeuNAc FT synthetase" FT /protein_id="AAG37023.1" FT /translation="MTLFYKIIAFLRLLKIDKKLKFDNEYFLNLNKKIYNEKHKGFFDF FT DPNSKDTKSPLNPWAFIRVKNEATTLRVSLESMLPAIQRGVIGYNDCTDGSEEIILEFC FT KQYPSFIPVKYPHEVQIENPQSEENKLHSYYNYVASFIPQDEWLIKIDVDHYYDAKKLY FT KSFYMASKNTAVRFPRINFLILDKIVIQNIGECGFIDGGDQLLIQKCNSVFIERMVSKQ FT SQWIDPEKTVKELYSEQQIIPKHIKILQAELLQWHFPALKYHRNDYQKHLDALTLEDFK FT KIHYRHRKIKKINYTMLDEKVIREILDKFKLSGKKMTLAIIPARAGSKGIKNKNLALLH FT DRPLLYYTINAAKNSKYVDKIVLSSDGDDILEYGQTQGVDVLKRPKELALDDTTSDKVV FT LHTLSFYKDYENIVLLQPTSPLRTNVHIDEAFLKFKNENSNALISVVECDNKILKAFID FT DNGNLKGICDNKYPFMPRQKLPKTYMSNGAIYIVKSNLFLNNPTFLQEKTSCYIMDEKA FT SLDIDTTEDLKRVNNISFL" XX SQ Sequence 4668 BP; 1917 A; 482 C; 742 G; 1527 T; 0 other; tagctcttta tttttttttg atataattat actataaatt taaggtaata aaatgagtat 60 gaatattaat gctttggtat gcggtaatgg acctagttta aaaaatatag attataaaag 120 gttaccaaaa caatttgatg tatttagatg caatcagttt tattttgaag atagatattt 180 tgtgggtaaa gatgtaaaat atgttttttt taatcctttt gtgttttttg aacaatacta 240 tactagtaaa aaacttatac aaaacgaaga atataacata gaaaatatag tttgttctac 300 tattaattta gaatacatag atggatttca atttgttgat aattttgaat tatactttag 360 tgatgctttt ttaggtcatg agattataaa aaagcttaaa gatttttttg cctatattaa 420 atataatgaa atatacaata ggcaaagaat tactagtgga gtttatatgt gtgctacagc 480 tgtggctctg ggatataaaa gtatatatat aagtggtatt gatttttatc aagatacaaa 540 taatttatat gccttcgata ataataaaaa aaatttatta aataaatgca ctggttttaa 600 aaatcaaaaa ttcaaattta tcaatcattc aatggcatgt gatttacaag ctttagatta 660 tctaatgaaa aggtatgatg tgaatattta tagtttaaat tcagatgagt attttaaatt 720 ggctccggat attggaagtg attttgtatt gagtaaaaaa ccaaaaaaat atataaatga 780 tatattgata ccagataagt atgcacaaga aagatattat ggaaaaaaaa gtaggttaaa 840 agaaaatctc cattataagc taataaaaga tctaattaga cttccaagtg acataaaaca 900 ctacttaaag gaaaaatatg caaataaaaa tagataaatt aactatttct cagaaaaatc 960 ctttgataat ccctgaaata ggtataaatc acaatggtag tttagaaata gcaaaactta 1020 tggtagatgc ggccaaaaga gcaggagcta agataataaa acaccaaact catatagtcg 1080 aagatgaaat gagccaagag gctaaaaatg ttataccggg taatgcaaat attagcattt 1140 atgagattat ggaacaatgt gcattaaact ataaagatga actagcttta aaagagtatg 1200 tagagaagca aggtttggta tatcttagca ctccatttag tagagctgca gcaaatcgtt 1260 tagaagatat gggtgtaagt gcttataaaa taggctcagg tgaatgtaat aattatcctt 1320 taataaaaca tatagcacaa tttaaaaaac ctatgattat aagcaccgga atgaatagca 1380 tagaaagtat aaaacccaca gttaagatac ttagagatta tgaaatacct tttgttttgc 1440 ttcatactac aaatttatat cctactccat cgcacttagt aagattacaa gctatgttag 1500 aattatataa agagtttaat tgtctttatg gacttagtga tcataccaca aacaatcttg 1560 catgtatagg tgcaatagct cttggagcaa gtgtactaga aagacacttt acagaatcca 1620 tggacagaaa aggccctgat atagtttgct ctatggatga aagcacttta aaagatctta 1680 taaatcaaac acaagaaatg gtgcttttaa gaggcgataa taataaaaat cctttaaaag 1740 aagagcaagt gaccattgat tttgcatttg ctagtgtagt aagtattaaa gatataaaaa 1800 agggtgaaat tttatctatg gataatattt gggtaaaaag accttcaaaa ggtggtataa 1860 gtgcaaagga ttttgaagcc atacttggaa aaagagcaaa aaaagatata aaaaataata 1920 tacaactaac atgggatgat tttgaatgaa aaaaatagtt tttgttagcg gaactagagc 1980 tgatttttct aaaataaaat ctctaatgat gaaagttgaa aattcaaatg aatttgaatt 2040 atttatattt gtaaccggta tgcatatgag taaaaagttt ggttctactt atatggaaat 2100 agaaaaatgt ggttttaaaa atatatataa atatataaat cacgataagt attatcagat 2160 ggataaggct ttatcatcaa caatagatgg tttttctaaa tttatacatg agatagagcc 2220 tgatttaata gtagtgcatg gtgatagagt ggagccttta gctgctgcta tagtaggaag 2280 tttaaataat atcttagtgg cacatataga aggcggagag ctttcaggaa ctatagatga 2340 gagtttaaga catgctatta gtaaattagc acatattcat ttagtaaatg atgaaatagc 2400 aaaaaaaaga ttaatacaaa tgggtgaaga tgagaaatct atttttatta taggttctcc 2460 tgatttagaa ttgctaaata atactatatc tttagatgaa gcaaaaaaat attatgatat 2520 aaaatttaaa aattatgcca tagctatatt tcatccaatt acaaccgaaa taaactcttt 2580 atataaacaa agtgaagaat ttgtaaatgc tcttataaaa agtgaaaaaa attatatagt 2640 tatttatcca aataatgatt taggatttga attaattttg caaaattatg aaaggctaaa 2700 aaataatgaa agatttaaaa tttttccttc tttaagattt gagtatttta taagtttgct 2760 aaaaaatgcc aattttatca taggaaattc aagttgtata ataaaagaag ctttatatct 2820 taatataaat ggaattttag ttggttcaag acaagatggt agaactgaca ttaataaaac 2880 aataagagta aatgcagagg aaaaggatat attggaagcg attttaaata ctagtaaatg 2940 cactaatatt acaaataaaa gactagaaat tttaaatagt tctgagcaat tttataggtt 3000 attgaaaaat aatattttat ttactataaa caagcaaaaa atattcatgg ataaaaaatg 3060 actttgtttt ataaaattat agctttttta agattgctta aaattgataa aaaattaaaa 3120 tttgataatg aatatttttt aaacttaaat aaaaaaatct acaatgaaaa gcataaaggt 3180 ttttttgatt ttgatccaaa ctcaaaagat acaaaatctc ctttaaatcc atgggctttt 3240 ataagagtaa aaaatgaagc cactacttta agagtatcac ttgaaagtat gttacctgcc 3300 atacaaagag gtgttatagg atataatgat tgtactgatg gaagtgaaga aattattttg 3360 gaattttgca aacaataccc ttcgtttata ccagtaaaat atccccatga ggtgcaaatt 3420 gaaaatccgc aaagcgaaga aaataaactt catagttatt ataactatgt agctagtttt 3480 ataccgcaag atgagtggct tataaaaata gatgtggatc attactatga tgcaaaaaaa 3540 ttatataaga gtttttatat ggcatcaaaa aatactgctg ttagatttcc aagaattaat 3600 tttttaatac tagataaaat tgtaattcaa aatataggag aatgtggttt tatcgatgga 3660 ggggatcaat tgttaattca aaagtgcaat agtgtattta tagaaagaat ggtttcaaag 3720 caaagtcagt ggattgatcc tgaaaaaact gtgaaagaat tgtattctga acagcaaatt 3780 atacccaaac atataaaaat cttacaagca gaattacttc aatggcattt tcctgcttta 3840 aaatatcata gaaatgatta tcaaaaacat ttggatgctt taactttaga agattttaaa 3900 aaaatccatt atagacatag aaaaataaag aaaataaatt atacaatgct tgatgaaaaa 3960 gtaattcgtg aaatattaga taaatttaaa ttgagtggta aaaaaatgac tttagctata 4020 atacctgctc gagctggttc aaaaggtata aaaaataaaa atttagctct tttgcatgat 4080 aggcctttgt tgtattatac tatcaatgca gcaaaaaatt caaagtatgt agataaaatt 4140 gttttaagta gtgatggcga tgatatatta gaatatggac aaactcaagg tgtagatgtg 4200 ttaaaaagac ctaaagaatt agcgctagat gatacaacta gtgataaggt tgtattgcat 4260 accttgagtt tttataaaga ttatgaaaat attgttttat tacaacccac ttctccttta 4320 aggacaaatg tacatataga tgaagctttt ttaaaattta aaaatgaaaa ctcaaatgca 4380 ttaataagtg ttgtagaatg tgataataaa attttaaaag cttttataga tgataatggt 4440 aacttaaaag gaatttgtga taacaaatat ccatttatgc ctagacaaaa attaccaaaa 4500 acttatatga gtaatggtgc aatttatata gtaaagtcaa atttattttt aaataaccca 4560 acttttctac aagaaaaaac aagttgctat ataatggacg aaaaagctag tttggatata 4620 gatacaacag aggatttaaa aagagttaat aatataagct tcttataa 4668 // |
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