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EBI DbfetchID AF224509; SV 3; linear; genomic DNA; STD; PRO; 15984 BP. XX AC AF224509; XX DT 22-AUG-2000 (Rel. 64, Created) DT 15-APR-2005 (Rel. 83, Last updated, Version 4) XX DE Bacteroides cellulosolvens cellulosomal scaffoldin precursor (cipBc), DE cellulosomal anchoring scaffoldin B (scaB), and sodium/calcium exchanger DE protein genes, complete cds. XX KW . XX OS Bacteroides cellulosolvens OC Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; OC unclassified Ruminococcaceae. XX RN [1] RP 1-15984 RX DOI; 10.1128/JB.182.17.4915-4925.2000 RX PUBMED; 10940036. RA Ding S.Y., Bayer E.A., Steiner D., Shoham Y., Lamed R.; RT "A scaffoldin of the Bacteroides cellulosolvens cellulosome that contains RT 11 type II cohesins"; RL J. Bacteriol. 182(17):4915-4925(2000). XX RN [2] RP 1-15984 RX DOI; 10.1128/JB.186.4.968-977.2004 RX PUBMED; 14761991. RA Xu Q., Bayer E.A., Goldman M., Kenig R., Shoham Y., Lamed R.; RT "Architecture of the Bacteroides cellulosolvens cellulosome: description of RT a cell surface-anchoring scaffoldin and a family 48 cellulase"; RL J. Bacteriol. 186(4):968-977(2004). XX RN [3] RP 1-15984 RA Ding S.-Y., Bayer E.A., Shoham Y., Steiner D., Lamed R.; RT ; RL Submitted (12-JAN-2000) to the EMBL/GenBank/DDBJ databases. RL Department of Biological Chemistry, The Weizmann Institute of Science, RL Rehovot 76100, Israel XX RN [4] RC Sequence update by submitter RP 1-15984 RA Ding S.-Y., Bayer E.A., Shoham Y., Steiner D., Lamed R.; RT ; RL Submitted (26-AUG-2003) to the EMBL/GenBank/DDBJ databases. RL Department of Biological Chemistry, The Weizmann Institute of Science, RL Rehovot 76100, Israel XX RN [5] RC Sequence update by submitter RP 1-15984 RA Xu Q., Bayer E.A., Goldman M., Kenig R., Shoham Y., Lamed R.; RT ; RL Submitted (28-AUG-2003) to the EMBL/GenBank/DDBJ databases. RL Department of Biological Chemistry, The Weizmann Institute of Science, RL Rehovot 76100, Israel XX CC On Jul 26, 2004 this sequence version replaced gi:34223561. XX FH Key Location/Qualifiers FH FT source 1..15984 FT /organism="Bacteroides cellulosolvens" FT /mol_type="genomic DNA" FT /db_xref="taxon:35825" FT gene 590..7622 FT /gene="scaA" FT CDS 590..7549 FT /codon_start=1 FT /transl_table=11 FT /gene="scaA" FT /product="cellulosomal scaffoldin precursor" FT /function="subunit integration" FT /db_xref="GOA:Q9FDJ9" FT /db_xref="InterPro:IPR018452" FT /db_xref="PDB:1TYJ" FT /db_xref="UniProtKB/TrEMBL:Q9FDJ9" FT /protein_id="AAG01230.2" FT /translation="MRTKRLLAVLLTTLLLLGSVFTNVSLAAAALSISVTLDKTTASVG FT DIITATISANGIQNFAGYQANVKYDPAVLQPVYSATEPYDGSSVPEYGTLLQKRYSPTD FT MGANDLANGSLTFGRTYMNLSGYMNPGSSESTGTLAIIKFKVLKKASTQIKLQNAASLT FT NAVDGTMVFDWTGAQLSNYSVERAPVLNDDGTKPSVAPTTAPTTVKPTAGPTSPVRPID FT SGVTVEVDKTDAKVGDIITATINVKNINGFAGYQANLKYNPAVLQPVYEDGTAYDNASA FT PEYGKLLQKRYSPTDMASNDITKGTLTFGRTYMNLDSYKNSGAAEKEGSIAVIRFKVLK FT VEATTITLQNAASLTNAVDGTMLFDWTGAQLAGYRVQQAPSINGVVVTTTPLPTVSTVP FT STTPLTGSGVEATVDKTTASVGDIITYTISVKDIAGFAGYQANVKYDPSVLKPVYEDGT FT EYDNAAVPDYGKLLQKRYSPTDMASNDLSKGTLTFGRTYMNLDSYKASGSAETSGSIAV FT IRFKVLKNTATTIKLQNAASLTNAVDGTMLFDWSGAQLAGYKVAQAPSINGVVVETPVP FT TVSLPPSQTIGSGVTATVDKTTASVGDIITYTINVKDVAGFAGYQANVKYDPSVLQPVY FT DDRSAYDSAAVPEYGTLLQKRYSPTDMASNDLSKGTLTFGRTYMNLDSYKASGSAETTG FT SIAVIRFKVLKNTATTIKLQNAASLTNAVDGTMLFDWSGAQLAGYKVAQAPSINGVVVE FT TPVPTVSVPPSQIPGSGVVATVDKTTASVGDIITYTINVKDVAGFAGYQANVKYDPAVL FT QPVYDDGTAYDSAAVPEYGTLLQKRYSPTDMASNDLSKGTLTFGRTYMALDSYKASGSA FT ETTGSIAVIRFKVLRSTATAILLQNAASLTNAVDGTMLFDWTGAQLKGYKVAQASSING FT TVTPTKPGNTPTITKPATPTKPANTPTPVQVNSDLKLLFSNNGAAASSNQICMNMKLQN FT TGSSTYDLSKITIRYFYTSDDDKALTYYSDYVSIGSASATFNNLSPVHAKANKYIEIKL FT ASGTLGAAGAQWPSQSEVTIQGRVAKADWTNVDQSNDYSYPGSMSQFGENKLVAVYYNG FT ALVYGTPPPTGPENTPTDRPTSTPTKPKNTPTPTKNTSTPIDGTVELSLDKTTAGVGDI FT ITATLKINKIPGFAGYQANIKYDPAALTPVYSDGTAYDDAAVPEYGDLLQKRYSPTDMA FT ANDVAKGTLTFGRTYMALDSYKASGSAETTGSIAVIRFKVLKSTGSTSIKLENAASLTN FT AVDGTMLFDWTGAQLGGYTVKQASTIKLGSGVTKGEVFVTLDKSTAAAGDIVTATINVK FT EFDVISGYQANIKYDPSALQPVYSDGTAYDSSSVPESGDLLQKRYSPTDMASNDLTKGT FT LTFGRTYMNLASYKTAGVKENTGSIAKISFKVLKSGPVSILLADSPSLTNAITGTMMFD FT WDGVQLDNYKVTQAGGSTTSPTPTQGITKGEVFVTLDKTKAAVGDIITATINVKDFDSV FT AGYQASVKYDPAVLQPVYSDGTAYDNSSVPEYGKLLQKRYSPTDMGANDTANGILTFGR FT TYMNLSGYKASGVAEKEGSIAVISFKVLKATETKVLLKNVPSLTSPVDGTMVFDWDGVQ FT LADYKVTQAPAVNAPVVVTPTPTTVSATPTTATATPTPTKVNTKGEVFVTLDKTTAAVG FT DIITATINVKDFDSVAGYQANIKFDPAVLKPVYSDGTAYDNSSVPEYGKLLQKRYSPTD FT MGANNLENGILTFGRTYMNMAGYKASGVAEKEGSIAVISFKVLKATETKIELKNVPSLT FT SPVDGTMVFDWDGVQLANYKVTQAPVVNGPVVVTPTPTTVSATPTTATATPTPTKVNTK FT GEVFVTLDKTTAAVGDIITATINVKDFDSVAGYQANIKFDPAVLKPVYSDGTAYDNSSV FT PEYGKLLQKRYSPTDMGANNLENGILTFGRTYMNMAGYKASGVAEKEGSIAVISFKVLK FT ATETKIELTNVPSLTNPVDGTMVFDWDGTQLANYKVTQAPAVNAPVVVTPTPTTATATP FT TTATATPTTATATPTPTTPVDGSVLTAIDNDKVAVGDKVTLTINVDKITNFSGYQFNIK FT YNTTYLQPWDTIADEAYTDSTMPDYGTLLQGRFNATDMSKHNLSQGVLNFGRLYMNLSA FT YRASGKPESTGAVAKVTFKVIKEIPAEGIKLATFENGSSMNNAVDGTMLFDWDGNMYSS FT SAYKVVQPGLIYPKGTATVLYGDVDNDGNVDSDDYAYMRQWLIGMIADFPGGDIGLANA FT DVDGDGNVDSDDYAYMRQWLIGMISEFPAEQK" FT sig_peptide 590..670 FT /gene="scaA" FT mat_peptide 671..7546 FT /gene="scaA" FT /product="cellulosomal scaffoldin" FT misc_feature 671..1153 FT /gene="scaA" FT /note="involved in subunit integration; Region: type-II FT cohesin domain 1" FT misc_feature 1262..1729 FT /gene="scaA" FT /note="involved in subunit integration; Region: type-II FT cohesin domain 2" FT misc_feature 1814..2281 FT /gene="scaA" FT /note="involved in subunit integration; Region: type-II FT cohesin domain 3" FT misc_feature 2357..2824 FT /gene="scaA" FT /note="involved in subunit integration; Region: type-II FT cohesin domain 4" FT misc_feature 2900..3367 FT /gene="scaA" FT /note="involved in subunit integration; Region: type-II FT cohesin domain 5" FT misc_feature 3479..3934 FT /gene="scaA" FT /note="family-III CBD; Region: cellulose binding domain" FT misc_feature 4043..4513 FT /gene="scaA" FT /note="involved in subunit integration; Region: type-II FT cohesin domain 6" FT misc_feature 4550..5014 FT /gene="scaA" FT /note="involved in subunit integration; Region: type-II FT cohesin domain 7" FT misc_feature 5066..5533 FT /gene="scaA" FT /note="involved in subunit integration; Region: type-II FT cohesin domain 8" FT misc_feature 5642..6109 FT /gene="scaA" FT /note="involved in subunit integration; Region: type-II FT cohesin domain 9" FT misc_feature 6218..6685 FT /gene="scaA" FT /note="involved in subunit integration; Region: type-II FT cohesin domain 10" FT misc_feature 6812..7297 FT /gene="scaA" FT /note="involved in subunit integration; Region: type-II FT cohesin domain 11" FT misc_feature 7316..7546 FT /gene="scaA" FT /note="involved in cell anchoring; similar to N-terminal FT dockerin domain; Region: dockerin domain" FT terminator 7580..7622 FT /gene="scaA" FT /standard_name="putative rho-independent transcription FT terminator" FT promoter 7624..7631 FT /standard_name="putative sigma A promoter" FT gene 7637..14551 FT /gene="scaB" FT RBS 7637..7642 FT /gene="scaB" FT CDS 7652..14551 FT /codon_start=1 FT /transl_table=11 FT /gene="scaB" FT /product="cellulosomal anchoring scaffoldin B precursor" FT /note="contains a signal peptide, 10 consecutive type-I FT cohesin modules that bind to the dockerin of the primary FT ScaA (CipBc) scaffoldin, an X domain (of unknown function) FT and a C-terminal SLH module that mediates attachment to the FT cell surface" FT /db_xref="GOA:Q6A564" FT /db_xref="InterPro:IPR018452" FT /db_xref="UniProtKB/TrEMBL:Q6A564" FT /protein_id="AAT79550.1" FT /translation="MQSPRLKRKILSVILAVCYIISSFSIQFAATPQVNIIIGSAQGIP FT GSTVKVPINLQNVPEIGINNCDFTIKFDSDILDFNSVEAGDIVPLPVASFSSNNSKDII FT KFLFSDATQGNMPINENGLFAVISFKIKDNAQKGISNIKVSSYGSFSGMSGKEMQSLSP FT TFFSGSIDVSDVSTSKLDVKVGNVEGIAGTEVNVPITFENVPDNGINNCNFTLSYDSNA FT LEFLTTEAGNIIPLAIADYSSYRSMEGKIKFLFSDSSQGTRSIKNDGVFANIKFKIKGN FT AIRDTYRIDLSELGSFSSKQNNNLKSIATQFLSGSVNVKDIESSVSPTTSVHPTPTSVP FT PTPTKSSPGNKMKIQIGDVKANQGDTVIVPITFNEVPVMGVNNCNFTLAYDKNIMEFIS FT ADAGDIVTLPMANYSYNMPSDGLVKFLYNDQAQGAMSIKEDGTFANVKFKIKQSAAFGK FT YSVGIKAIGSISALSNSKLIPIESIFKDGSITVTNKPIVNIEIGKVKVKAGDKIKVPVE FT IKDIPSIGINNCNFTLKYNSNVLKYVSNEAGTIVPAPLANLSINKPDEGIIKLLFSDAS FT QGGMPIKDNGIFVNLEFQAVNDANIGVYGLELDTIGAFSGISSAKMTSIEPQFNNGSIE FT IFNSAQTPVPSNTEVQTPTNTISVTPTNNSTPTNNSTPKPNPLYNLNVNIGEISGEAGG FT VIEVPIEFKNVPDFGINNCDFSVKYDKSIFEYVTYEAGSIVKDSIVNLACMENSGIINL FT LFNDATQSSSPIKNNGVFAKLKFKINSNAASGTYQINAEGYGKFSGNLNGKLTSINPIF FT ENGIINIGNVTVKPTSTPADSSTITPTATPTATPTIKGTPTVTPIYWMNVLIGNMNAAI FT GEEVVVPIEFKNVPPFGINNCDFKLVYDSNALELKKVEAGDIVPEPLANLSSNKSEGKI FT QFLFNDASQGSMQIENGGVFAKITFKVKSTAASGIYNIRKDSVGSFSGLIDNKMTSIGP FT KFTDGSIVVGTVTPTATATPSAIVTTITPTATTKPIATPTIKGTPTATPMYWMNVVIGK FT MNAEVGGEVVVPIEFNNVPSFGINNCDFKLVYDATALELKNVEAGDIIKTPLANFSNNK FT SEEGKISFLFNDASQGSMQIENGGVFAKITFKVKSTTATGVYDLRKDLVGSFSGLKDNK FT MTSIGAEFTNGSITVAATAPTVTPTVNATPSAATPTVTPTATATPSVTIPTVTPTATAT FT PSVTIPTVTPTATATPSAATPTVTPTATATPSVTIPTVTPTVTATPSDTIPTVTPTATA FT TPSAIVTTITPTATAKPIATPTIKGTPTATPMYWMNVVIGKMNAEVGGEVVVPIEFKNV FT PSFGINNCDFKLVYDATALELKNVEAGDIIKTPLANFSNNKSEEGKISFLFNDASQGSM FT QIENGGVSAKITFKVKSTTAIGVYDIRKDLIGSFSGLKDSKMTSIGAEFTNGSITVATT FT APTVTPTATATPSVTIPTVTPTATATPGTATPGTATPTATATPGAATPTETATPSVMIP FT TVTPTATATPTATATPTVKGTPTIKPVYKMNVVIGRVNVVAGEEVVVPVEFKNIPAIGV FT NNCNFVLEYDANVLEVKKVDAGEIVPDALINFGSNNSDEGKVYFLFNDALQGRMQIAND FT GIFANITFKVKSSAAAGIYNIRKDSVGAFSGLVDKLVPISAEFTDGSISVESAKSTPTA FT TATGTNVTPTVAATVTPTATPASTTPTATPTATSTVKGTPTATPLYSMNVIIGKVNAEA FT SGEVVVPVEFKDVPSIGINNCNFILEYDASALELDSAEAGEIVPVPLGNFSSNNKDEGK FT IYFLFSDGTQGRMQIVNDGIFAKIKFKVKSTASDGTYYIRKDSVGAFSGLIEKKIIKIG FT AEFTDGSITVRSLTPTPTVTPNVASPTPTKVVAEPTSNQPAGPGPITGTIPTATTTATA FT TPTKASVATATPTATPIVVVEPTIVRPGYNKDADLAVFISSDKSRYEESSIITYSIEYK FT NIGKVNATNVKIAAQIPKFTKVYDAAKGAVKGSEIVWMIGNLAVGESYTKEYKVKVDSL FT TKSEEYTDNTVTISSDQTVDIPENITTGNDDKSTIRVMLYSNRFTPGSHSSYILGYKDK FT TFKPKQNVTRAEVAAMFARIMGLTVKDGAKSSYKDVSNKHWALKYIEAVTKSGIFKGYK FT DSTFHPNAPITRAELSTVIFNYLHLNNIAPSKVHFTDINKHWAKNYIEEIYRFKLIQGY FT SDGSFKPNNNITRAEVVTMINRMLYRGPLKVKVGSFPDVSPKYWAYGDIEEASRNHKYT FT RDEKDGSEILIE" FT sig_peptide 7652..7738 FT /gene="scaB" FT mat_peptide 7739..14548 FT /gene="scaB" FT /product="cellulosomal anchoring scaffoldin B" FT misc_feature 7739..8185 FT /gene="scaB" FT /note="Region: type-I cohesion domain 1" FT misc_feature 8186..8620 FT /gene="scaB" FT /note="Region: type-I cohesion domain 2" FT misc_feature 8696..9139 FT /gene="scaB" FT /note="Region: type-I cohesion domain 3" FT misc_feature 9140..9604 FT /gene="scaB" FT /note="Region: type-I cohesion domain 4" FT misc_feature 9683..10126 FT /gene="scaB" FT /note="Region: type-I cohesion domain 5" FT misc_feature 10223..10648 FT /gene="scaB" FT /note="Region: type-I cohesion domain 6" FT misc_feature 10766..11188 FT /gene="scaB" FT /note="Region: type-I cohesion domain 7" FT misc_feature 11597..12019 FT /gene="scaB" FT /note="Region: type-I cohesion domain 8" FT misc_feature 12293..12730 FT /gene="scaB" FT /note="Region: type-I cohesion domain 9" FT misc_feature 12875..13312 FT /gene="scaB" FT /note="Region: type-I cohesion domain 10" FT misc_feature 13499..13936 FT /gene="scaB" FT /note="Region: unknown domain" FT misc_feature 13937..14548 FT /gene="scaB" FT /note="involved in mediating attachment to the cell FT surface; Region: SLH module" FT -35_signal 14757..14762 FT -10_signal 14780..14785 FT RBS 14896..14901 FT CDS 14947..15984 FT /codon_start=1 FT /transl_table=11 FT /product="sodium/calcium exchanger protein" FT /note="Scx" FT /db_xref="GOA:Q6A563" FT /db_xref="InterPro:IPR004837" FT /db_xref="UniProtKB/TrEMBL:Q6A563" FT /protein_id="AAT79551.1" FT /translation="MQYKGKGYMQIYIILLFLGLIIILLSCELFTNAIEWFGKKLNFGD FT GVIGSIFSAVGTCLPETLIPIIAIIKSGKSGEDSSLDVGIGAILGAPFMLSTLAFFITG FT FSVILFCKKRKSGLSIKINKKIFGRDMEFFALMYSIAITMSFIENYTAKVIISIGLILM FT YVYYVFLTVKHDKTSVDRLEKLYILKFSQSKVSLTAILLQLSIALTGIVSGSYIFVSNI FT EGISQALKISPMILALIITPIATELPEKFNSIIWIRKGKDSLALGNISGAMVFQSCIPV FT AVGIVFTTWKLNNTAMVSCVLSLVSSVILLLWMKVKKELTPLPFIFCGVLYILFIIYLT FT NGVFH" XX SQ Sequence 15984 BP; 5888 A; 2625 C; 3156 G; 4315 T; 0 other; aatacgacag aaaacaaatg gattgtgtgt ttgtatattt ataggacaag gttaatcatt 60 ttaagtattc gctaaatttg cttcatggtc gccttggttt ctctgattac ttaatagggg 120 gtaattgtta tttaaaagaa ttaaactgaa ttgtttactt ataatccaga cagttataaa 180 gttcatttta aagaagttaa atgaactcta tataatgttt aggtttaatt cttttagagg 240 catttattac aatttaaaaa gaggaggggg gatatagcgg atggttttgt taggtatagg 300 taaagtgatt ttgtaaatat acctaagtgc ttttattaaa catcaagtag ttagttttag 360 attatattaa gaagttgtat tggcgattat aggaagcgta taataattag tctgacaatt 420 tgatgaaact attgtctagt ggagaaggta agtgtcgggc tgttaattat aattataatt 480 ttaaggatag cagtttagaa gcactgaatt tatcaaattt tgattaagga ggttataaaa 540 aagtaaaaga atagaaaagt tatataataa ataagggggt ttataatcga tgagaacaaa 600 aagacttttg gcagttttgc taacgacttt gttgttgctt ggaagtgttt tcacaaatgt 660 gtcgttagct gcagcagcac tttccatctc agttactctt gacaaaacga cagcatcagt 720 tggcgacatt ataacagcaa caatcagtgc aaatggtatt cagaactttg caggatatca 780 agctaatgtt aagtatgatc ctgcagtatt gcaaccagtt tactcagcaa cagaaccgta 840 tgacggttca tcagtacctg aatatggaac gttattacag aagagataca gcccaacaga 900 catgggtgca aatgatcttg caaatggatc acttacattt ggaagaacat atatgaactt 960 gtcaggatac atgaatcctg gttcatcaga atcaactggt actttggcta taatcaagtt 1020 taaagtattg aaaaaagcat caactcaaat aaagctccag aatgcagcaa gtttaacaaa 1080 tgcagttgac ggtactatgg tgtttgattg gacaggtgca cagctttcga attactcagt 1140 tgaacgagca cctgttttaa atgatgatgg tactaaacca tcagtagcac caacaacagc 1200 accaacaaca gtaaaaccta cagcgggtcc aacttcacca gttcgaccta tagattcagg 1260 tgtaactgta gaggtagata agactgatgc taaagttggt gacataataa cagctactat 1320 taatgtaaaa aatataaacg gatttgcagg ataccaagca aatcttaagt ataatcctgc 1380 agtattgcaa ccagtttacg aagatggaac tgcatatgat aatgcatcag ctcctgaata 1440 tggtaagttg ttgcagaaga gatacagtcc aacagatatg gcatcaaatg atattactaa 1500 aggaacactt acctttggta gaacatacat gaatttggat tcatacaaga attctggagc 1560 agcagaaaaa gaaggttcaa tagctgtaat cagattcaaa gtattaaaag ttgaagcaac 1620 aactataact ttgcagaatg cagcaagttt aacaaatgca gttgacggaa caatgttatt 1680 tgattggaca ggagctcaat tagcaggata tagagttcaa caagctcctt caataaatgg 1740 agttgttgta acaacaacac cattacctac agtttcaaca gtaccttcca caacaccatt 1800 aacaggttca ggtgtagaag caactgtaga taagacaact gcatcagtag gcgatatcat 1860 aacatataca atcagtgtta aggatatagc tggatttgca ggatatcagg caaatgttaa 1920 atatgatcca tcagtattga agccagttta tgaagatgga acagaatatg acaatgcagc 1980 agtacctgat tatggtaagt tattacagaa gagatacagt ccaacagaca tggcatcaaa 2040 tgatctttca aagggaacac ttacttttgg tagaacatac atgaacttgg attcatacaa 2100 ggcatcagga tcagcagaaa caagtggttc aatagctgtt attagattca aagtattgaa 2160 aaatacagct acaactatta agttacagaa tgctgcaagc ttgacaaatg cagttgatgg 2220 aacaatgtta ttcgattgga gcggagcaca attagcagga tataaagtag cacaggctcc 2280 ttcaataaac ggagttgttg tagaaactcc agtaccaaca gtgtcactac caccatcaca 2340 gacaattggt tcaggtgtaa cagcaactgt agataagaca actgcatcag taggcgatat 2400 cataacatat acaatcaatg ttaaggatgt agctggattt gcaggatatc aggcaaatgt 2460 taaatatgac ccatcagtat tgcagccagt ttatgatgat cgatcagcat acgatagtgc 2520 agcagtacct gaatacggaa cattgttgca gaagagatac agcccaacag acatggcatc 2580 aaatgatctt tcaaagggaa cacttacctt tggtagaaca tacatgaatt tggattcata 2640 caaggcatca ggatcagcag aaacaactgg ttcaatagct gttattagat tcaaagtatt 2700 gaaaaataca gctacaacta ttaagttaca gaatgctgca agtttaacaa atgcagttga 2760 tggaacaatg ttattcgatt ggagcggagc acaattagca ggatataaag tagcacaggc 2820 tccttcaata aacggagttg ttgtagaaac tccagtacca acagtgtcag taccaccatc 2880 acagatacct ggttcaggag tagtagcaac tgtggataag acaactgcat cagtaggcga 2940 tatcataaca tatacaatca atgttaagga tgtagctgga tttgcaggat atcaggcaaa 3000 tgttaaatat gatccagcag tattgcagcc agtttacgat gatggaacag catatgatag 3060 tgcagcagta cctgaatatg gaacattgtt acagaagaga tacagcccaa cagacatggc 3120 atcaaatgat ctttcaaagg gaacacttac ctttggtaga acatacatgg cgttggattc 3180 atacaaagca tcaggatcag cagaaacaac tggttcaata gctgttatta gattcaaagt 3240 attaaggtct actgcaacag ctatattgtt acaaaatgct gcaagcttga caaatgcagt 3300 tgatggaaca atgttatttg actggacagg agcacagtta aaaggatata aagtagcaca 3360 ggcttcttca ataaacggaa ctgttactcc aacaaaacca ggaaatacac caacaataac 3420 aaaaccagca acaccaacaa aaccagcaaa tacaccaaca cctgtacaag ttaacagcga 3480 cttgaagttg ttgttcagca acaatggtgc agcagcaagc tcaaatcaga tttgcatgaa 3540 catgaagtta caaaatacag gatcatcaac atatgatctt tcaaaaatta caattagata 3600 cttctacaca agtgatgatg ataaagcatt aacttattac tcagactatg taagtattgg 3660 ttcagcaagt gctacattca acaatttatc accagtacat gcaaaggcta ataagtatat 3720 agaaattaaa ttggcatccg gaacacttgg agcagctggt gcacagtggc caagtcaatc 3780 tgaagtaaca attcagggta gagttgcaaa agctgactgg actaatgttg atcaatcaaa 3840 tgactattca tatccaggtt caatgagtca gtttggagaa aacaaacttg ttgcagttta 3900 ttacaatgga gctttggtat atggtacgcc accaccaact ggtccagaaa atacaccaac 3960 agatagacca acaagtacac caacaaaacc aaaaaatact ccaacaccga ccaaaaatac 4020 atctacacca atagatggta cagtagaatt aagtcttgat aaaacaactg caggagttgg 4080 agatattatt acagctacac tgaaaattaa taaaatccct ggttttgcag gatatcaggc 4140 taatattaaa tacgatccag cagcgttgac acctgtatac tcagatggaa cagcatatga 4200 tgatgctgca gtacctgagt atggtgattt actccagaag agatacagcc caacagatat 4260 ggcggcaaat gatgttgcta agggaacact tacttttggt agaacataca tggctttgga 4320 ttcatacaag gcatcaggat cagcagaaac aacaggatct atagcagtaa ttagattcaa 4380 ggttctcaaa tcaactggtt caacatccat taagttagag aatgcagcta gcttgacaaa 4440 tgcggttgat ggaacaatgc tatttgactg gacaggagct cagttaggcg gatatacagt 4500 taaacaagca tcaacaatta aacttggatc aggagtaaca aaaggtgaag tattcgtaac 4560 attagacaag tcaacagcag cagctggaga tattgttaca gcaacaatta atgttaagga 4620 atttgatgta atatcaggat atcaagcaaa cattaagtat gatccttcag cattacaacc 4680 tgtatactca gatggaacag catatgacag ttcatcagta cctgaaagtg gtgatttact 4740 ccagaagaga tacagcccaa cagatatggc atcaaatgat cttacaaagg gaacactcac 4800 atttggaaga acatatatga acttggcaag ttataaaaca gcaggagtaa aagaaaatac 4860 aggatcaatt gctaagatct cattcaaggt acttaagagt ggtccagtaa gcatcttgtt 4920 agctgattca ccaagcctta caaatgcaat aacaggaaca atgatgttcg actgggatgg 4980 agttcagttg gacaattata aagtaacaca ggcaggtggt tcaacaacat cacctacacc 5040 aactcaggga ataacaaaag gtgaagtatt tgtaacatta gacaagacaa aagcagcagt 5100 gggcgacata attacagcaa caatcaacgt taaagatttt gactctgttg caggatatca 5160 ggcaagtgtt aaatatgatc cagcagtatt gcagccagta tactcagatg gaacagcata 5220 tgataattca tcagtacctg aatacggtaa gttactccag aagagatata gtccaacaga 5280 catgggtgca aatgatactg caaatggaat acttacattc ggaagaactt acatgaattt 5340 gtccggatat aaggcatcag gagtagcaga aaaagaagga tcaatagcag taatttcctt 5400 caaggtattg aaggctactg aaactaaagt attattgaaa aatgtaccaa gcctcacaag 5460 tccagttgac ggaacaatgg tatttgactg ggatggagta cagttggcag actacaaagt 5520 aacacaggca ccagcagtta atgctccagt tgttgtaaca ccaacaccaa ctactgtttc 5580 ggcaacacca actactgcaa cagcaacacc aacaccaact aaggtaaata caaaaggtga 5640 agtgtttgta acattagata agacaacagc agcagtaggc gacataatta cagcaacaat 5700 caacgttaaa gactttgatt cagttgcagg atatcaggct aatattaagt ttgatccagc 5760 agtattgaaa ccagtatact cagatggaac agcatatgat aattcatcag tacctgaata 5820 cggtaagtta ctccagaaga gatacagccc aacagacatg ggagcaaata atcttgaaaa 5880 tggaatactt acatttggaa gaacttacat gaatatggca ggatacaagg catcaggagt 5940 agcagaaaaa gaaggatcaa tagcagtaat atcctttaag gtattgaagg ctactgaaac 6000 taagatagaa ttgaaaaatg taccaagcct cacaagtcca gttgacggaa caatggtatt 6060 tgactgggat ggagtacagt tggcaaacta caaagtaaca caggcaccag tagttaatgg 6120 tccagttgtt gtaacaccaa caccaactac tgtttcggca acaccaacta ctgcaacagc 6180 aacaccaaca ccaactaagg taaatacaaa aggtgaagtg tttgtaacat tagataagac 6240 aacagcagca gtaggcgaca taattacagc aacaatcaac gttaaagact ttgattcagt 6300 tgcaggatat caggctaata ttaagtttga tccagcagta ttgaaaccag tatactcaga 6360 tggaacagca tatgataatt catcagtacc tgaatacggt aagttactcc agaagagata 6420 cagcccaaca gacatgggag caaataatct tgaaaatgga atacttacat ttggaagaac 6480 ttacatgaat atggcaggat acaaggcatc aggagtagca gaaaaagaag gatcaatagc 6540 agtaatatcc tttaaggtat tgaaggctac tgaaactaag atagaattga caaatgtacc 6600 aagcctcaca aatccagttg acggaacaat ggtatttgat tgggatggaa cacagttggc 6660 aaactacaaa gtaacacagg caccagcagt taatgctcca gttgttgtaa caccaacacc 6720 aactactgcc actgcaacac caactactgc tacagcaaca ccaactactg ctacagctac 6780 accaacacct actacacctg tagatggatc tgtattgaca gctattgata atgataaggt 6840 tgcagttggt gataaagtaa cacttacaat aaatgttgac aagataacta atttctcagg 6900 ctaccagttt aacatcaagt acaatacaac atacttacag ccttgggata caattgctga 6960 cgaagcatac actgattcaa caatgcctga ttatggaaca ttgttgcagg gaagatttaa 7020 cgcaacagac atgtctaagc ataacctttc acaaggtgta ttgaacttcg gtagattgta 7080 tatgaacctt tcagcataca gagcatcagg caaacctgaa agtactggag ctgttgcaaa 7140 ggtaacattt aaagtaatta aagaaatacc tgcagaagga attaagttgg caacatttga 7200 aaacggaagc agcatgaata atgcagttga tggaacaatg ttgttcgact gggatggcaa 7260 tatgtacagc tcaagtgcat acaaagtagt acaacctgga ctcatctatc caaaaggcac 7320 agctacagta ttatatggtg acgttgataa tgatggaaat gttgattcag acgactatgc 7380 atatatgaga caatggttga tcggtatgat tgctgatttc cctggaggag atatcggatt 7440 agctaatgct gatgttgatg gagacggaaa tgtagattca gatgactatg cgtacatgag 7500 acaatggtta ataggaatga tttccgagtt cccagcagaa caaaaataat aataaataaa 7560 attaataaat aagtagtcta attcgagtat tcccgaaact ttgtttcggg aatacttgaa 7620 ttcaataatt ttatgaaggg ggagaatatc attgcagagc ccaagattaa aacgcaaaat 7680 tttatctgta atattagcag tttgctatat tatatcatcg ttttcaattc aatttgctgc 7740 aacgcctcaa gttaatatca taataggctc cgctcaagga attccgggga gtacagttaa 7800 agtaccaatt aatttacaga atgtacctga gatagggatt aataactgtg atttcacaat 7860 aaagtttgat tctgatatat tagactttaa ttcagttgag gccggggata tcgtaccact 7920 tccagtagct agttttagta gtaataattc aaaagacatc attaagtttt tatttagtga 7980 tgctacccaa ggaaatatgc caataaacga aaatggttta tttgctgtca taagttttaa 8040 aattaaggat aatgcccaaa aaggtataag caatattaaa gtatcatcat atggatcttt 8100 ttctggaatg tcagggaaag aaatgcaatc attaagtcca actttttttt caggttctat 8160 agatgtttca gatgttagca caagtaaatt agatgttaaa gttgggaatg tagagggtat 8220 tgcaggaacg gaagtaaatg tacctattac atttgaaaac gtgcctgata atggaataaa 8280 taattgtaat tttaccttat cttatgattc aaatgcacta gagtttttaa caacagaagc 8340 tggaaatata atacctttag caattgctga ctattcgagt tatagatcaa tggaagggaa 8400 aataaagttc ctttttagtg attcttcaca ggggaccaga tcaattaaaa atgatggagt 8460 ctttgcaaat attaaattta aaataaaagg caatgctata agggatacat atagaataga 8520 tctatctgaa ttaggttcat tttcgagtaa acaaaataat aatttaaaat caatagccac 8580 tcagttttta agtggaagtg taaatgtaaa agatatagaa agcagtgttt ctccaacaac 8640 aagtgtgcat cctacaccaa ctagtgtgcc acctacacca acgaaaagtt caccaggaaa 8700 taaaatgaaa attcaaattg gtgatgtaaa agctaatcag ggagatacag ttatagtacc 8760 tataactttc aatgaagttc ctgtaatggg tgttaataac tgtaatttca ctttagctta 8820 tgacaaaaat attatggaat ttatctctgc tgatgcaggt gatattgtaa cattgccaat 8880 ggctaactat agctacaata tgccatctga tgggctagta aaatttttat ataatgatca 8940 agctcaaggt gcaatgtcaa taaaagaaga tggtactttt gctaatgtta aatttaaaat 9000 taagcagagt gccgcatttg ggaaatattc agtaggcatc aaagcaattg gttcaatttc 9060 cgctttaagc aatagtaagt taatacctat tgaatcaata tttaaagatg gaagcattac 9120 tgtaactaat aagccaattg ttaatataga aattggtaaa gttaaagtta aagctggaga 9180 taaaattaaa gtgcctgttg agattaagga tattccatca attgggataa ataactgtaa 9240 ttttacacta aaatataatt ctaatgtttt aaaatatgta tcaaatgaag ctggtacaat 9300 agttccggca ccgctagcta atttgagcat aaataaacca gatgaaggta ttattaagct 9360 attatttagt gatgcatctc aaggtggaat gccaataaag gataatggta tttttgtgaa 9420 tttagaattt caagcagtta acgatgctaa tattggtgtt tacgggttag aacttgatac 9480 tattggtgct ttttctggaa tatcatcagc aaaaatgact tcaattgaac ctcaatttaa 9540 taatggcagc attgaaattt ttaattctgc tcaaacacct gtgcctagca atactgaggt 9600 acaaacacca actaatacaa tctcagttac tccaacaaat aattctactc caacaaataa 9660 ttctactcca aaaccaaacc cgttgtataa tctcaatgta aatattggag agattagtgg 9720 agaagcaggt ggagttatag aggtaccaat tgaatttaaa aatgtaccgg attttggaat 9780 taacaattgc gatttttcgg ttaaatatga taaaagtatc tttgaatacg taacatatga 9840 agctggaagt attgtcaagg attcaatagt aaatttggca tgtatggaga atagcggaat 9900 aattaatttg ctttttaatg atgcaactca aagtagttca ccaataaaaa acaatggagt 9960 ttttgccaaa ctgaaattca agataaatag taatgcagct tcaggtactt atcaaattaa 10020 tgctgaaggc tatggaaagt tctctggtaa tttaaatggc aaattgacat caattaatcc 10080 aatattcgag aatggtatta taaatattgg gaatgttact gttaaaccta ctagtacacc 10140 tgcagattct tctacgatta caccaactgc tacaccgact gctacgccaa caataaaagg 10200 aacacctaca gttactccta tatactggat gaatgtactg ataggaaata tgaatgcagc 10260 gataggagaa gaagtagtag tacctataga atttaagaat gtacctccat ttgggattaa 10320 taattgtgac tttaaactgg tgtatgattc aaatgcattg gagttaaaga aggtagaagc 10380 tggtgatata gtacctgagc cattagcaaa cttaagcagt aataagtcag aagggaaaat 10440 acaattcctg tttaatgatg catcgcaagg cagtatgcaa atagaaaatg gcggggtatt 10500 tgcaaagata acatttaaag taaagagtac tgcggcttca ggcatatata atataagaaa 10560 agattcagtg ggatcttttt caggtctgat tgataataag atgacctcaa taggtccaaa 10620 atttacagac ggaagtattg tagttgggac tgtaacacca acagcaactg caacaccaag 10680 tgctatagtt acaacaataa cacctacagc aactacaaaa ccaattgcaa caccaacaat 10740 aaaaggaaca cctacagcta ctcctatgta ctggatgaat gtagtgatag gaaagatgaa 10800 tgcagaagta ggaggagaag tagtagtacc gatagagttt aataacgtgc catcatttgg 10860 gattaacaac tgcgacttta aacttgtata tgatgcaact gcactggagt taaagaacgt 10920 agaagctggt gatataatta aaactccgtt ggctaatttt agcaataaca agtcggagga 10980 aggaaagata agtttcctat tcaatgatgc atcgcaaggc agtatgcaaa tagaaaatgg 11040 cggggtattc gcgaagataa catttaaagt taagagtact acagccacag gtgtttatga 11100 cctaaggaaa gatttggtcg gatcgttctc aggacttaaa gataataaaa tgacctcaat 11160 aggagcggaa tttacaaacg gaagtataac agttgcagct acagcaccaa cagtgacacc 11220 tacagtaaat gcaacaccaa gtgctgcaac accaacagta acaccaacag caactgcgac 11280 accaagtgtt acaataccaa cggtaacacc aacagcaact gcgacaccaa gtgttacaat 11340 accaacggta acaccaacag caactgcaac accaagtgct gcaacaccaa cggtaacgcc 11400 gacggcaact gcgacaccaa gtgttacaat accaacagta acgccaacag taactgcgac 11460 accaagtgat actataccaa cagtaacacc aacagcaact gcaacaccaa gtgctatagt 11520 tacaacaata acacctacag caactgcaaa accaattgca acaccaacaa taaaaggaac 11580 acctacagct actcctatgt actggatgaa tgtagtgata ggaaagatga atgcagaagt 11640 aggaggagaa gtagtagtac cgatagagtt taagaacgtg ccatcatttg ggattaacaa 11700 ctgcgacttt aaacttgtat atgatgcaac tgcactggag ttaaagaacg tagaagctgg 11760 tgatataatt aaaactccgt tggctaattt tagcaataac aagtcggaag aaggaaagat 11820 aagtttctta ttcaatgatg catcgcaagg cagtatgcaa atagaaaatg gcggggtatc 11880 tgcaaagata acatttaaag ttaagagtac tacagctata ggtgtttatg acataaggaa 11940 agatttgatt ggatcgttct caggacttaa agatagtaag atgacctcaa taggagcaga 12000 atttacaaac ggaagtataa cagttgcaac tacagcacca acagtgacac ctacagcaac 12060 tgcgacacca agtgttacaa taccaacagt aacaccaaca gcaactgcaa caccaggtac 12120 tgcaacacca ggtactgcaa caccaacggc aactgcaaca ccaggtgctg caacaccaac 12180 ggaaactgcg acaccaagtg ttatgatacc aacagtaacg ccgactgcaa ctgcaacacc 12240 gactgcaact gcaacaccaa cagttaaagg aactcctaca attaaacctg tatacaagat 12300 gaatgtagtg ataggaaggg ttaatgtagt tgcaggagaa gaagtagtag taccagtaga 12360 gtttaagaat attccagcaa ttggagttaa caattgcaac tttgtactgg aatatgatgc 12420 aaatgtgttg gaagtaaaga aggtagatgc aggtgaaata gttccggatg cactaataaa 12480 cttcggcagt aataattcag acgaaggaaa ggtatacttc ctatttaatg atgcattaca 12540 gggcagaatg cagatagcta atgatggaat ctttgcaaat ataacattta aagtaaaaag 12600 tagtgcagca gctggtatat ataatataag aaaagattca gtaggagcat tctcaggatt 12660 ggttgataag ttggtcccaa taagtgcaga atttacagac ggaagtatat cagtggagtc 12720 tgcaaaatca acacctactg caactgcaac aggaacaaat gtaacaccta ctgtagctgc 12780 aacagtgaca ccaactgcga caccagcaag cacaactcca actgctacgc caacagctac 12840 ttcaacggta aaagggactc ctacagctac gcctttatac agtatgaatg taataatagg 12900 aaaggtgaat gcagaagcat caggagaagt agttgtacca gtagagttta aggatgtacc 12960 atcaattgga attaacaatt gtaactttat actggaatat gacgcaagtg cattggagtt 13020 agacagtgca gaagcaggcg aaatagtacc tgttccatta ggaaacttca gtagcaataa 13080 taaagacgaa ggaaagatat acttcctgtt tagtgatgga acacaaggca gaatgcaaat 13140 agttaatgat ggaatatttg caaaaataaa atttaaagta aagagtactg catctgatgg 13200 tacatattat ataagaaaag attcagtagg agcattttct ggactcattg aaaagaagat 13260 tatcaaaata ggtgcagaat ttacagacgg aagtataaca gtaaggtcgt taacaccaac 13320 acctacagtg acgccaaatg tagcaagccc aactccaaca aaagttgttg ctgagccaac 13380 aagtaatcaa ccagctggac ctggacctat tacaggtaca ataccaacag caactactac 13440 agcaacagca actccaacaa aagcgtcagt tgctacagcg acacctactg caactccaat 13500 tgttgttgta gagccaacaa tagtaagacc tggctacaat aaggatgcag acttggcagt 13560 gtttataagt tcagacaaga gcaggtatga agaatcaagt ataataactt actctattga 13620 atacaagaat attggtaaag tcaatgctac aaacgttaaa atagcagcac agatacctaa 13680 gtttactaaa gtttatgatg cagccaaggg tgcagtaaag ggaagtgaaa ttgtatggat 13740 gataggtaat cttgctgtag gcgaatcata tacaaaagag tataaagtta aagttgattc 13800 attgactaaa tcagaggagt atacagataa tacagttaca attagcagtg atcaaacagt 13860 tgatatacct gaaaatatca ctactggaaa tgatgataaa tcaacaatta gagtaatgct 13920 atactccaat agatttacac caggtagcca tagttcgtac atattaggat ataaggataa 13980 aacattcaag cctaagcaaa atgttacaag agctgaggta gctgcaatgt ttgctcgtat 14040 tatgggactt actgtgaagg atggtgcaaa aagcagttat aaggatgttt ccaataagca 14100 ttgggcattg aaatatattg aagcggtaac gaagagtgga atattcaagg gatataagga 14160 ttctactttc catccgaatg cacctataac tagggcagag ttgtccacag taatatttaa 14220 ttacctgcat cttaataata tagcaccatc aaaggtacat tttactgaca ttaataagca 14280 ctgggctaaa aactatattg aagagatata caggtttaaa ctaattcagg gttatagtga 14340 tgggtcattt aaaccaaaca acaatataac ccgtgcagaa gttgttacaa tgattaatag 14400 aatgctttat agaggacctc ttaaggtgaa agtgggttca ttcccagatg tatcgccaaa 14460 atactgggca tatggagata ttgaagaagc atctagaaat cataaataca ctagagatga 14520 gaaggatgga agcgaaatat taattgaata ataagaagta attaattgaa taataagaag 14580 tatatgtaat atatattaat cacttttaat aaggattaat tatatggagt gttgtaatat 14640 tgcttacaca agcagtttgc aacctccttt tttattgtct gtatacacat gccataacat 14700 ggcacatagg aattatgtaa tcctcggaac gaacaatgca aaatgacttt gttactttgt 14760 tattttatta aacatgtatt atatgaatat tagtgctttt ttgagaatag ttattataat 14820 atgagatgct cattaaggaa ttattaaaat atctattccg atttctatgt gagtgttgac 14880 gagttaagtc aactaagggg gcaagtttta gcagaagtta tattttaatc attccgtggt 14940 gaaatgatgc aatataaagg aaaaggttat atgcaaatat atattatatt attgttttta 15000 gggctaatca taatactgtt aagttgtgaa ttatttacaa atgcaataga atggtttggg 15060 aaaaagctaa actttgggga tggagttata ggaagcattt tttcagcggt tggtacatgt 15120 ctgcctgaaa cactaattcc gataatagca attataaaat caggaaaaag cggagaagac 15180 agctctttag atgttggtat aggtgcaata ttaggtgcac cttttatgct gagtacgctg 15240 gcatttttta taactgggtt tagtgttata cttttctgta aaaaacgaaa aagcggcctt 15300 agcattaaga taaataaaaa aatatttggc agggatatgg agttttttgc attaatgtac 15360 tctattgcaa taacaatgtc atttatagaa aattacactg caaaagtgat aatatctatc 15420 gggctgatat taatgtatgt atactatgtt tttctaactg taaagcacga taaaacttct 15480 gtagataggc ttgaaaagct atatatatta aagttttctc aatcaaaggt aagtttgact 15540 gcaattttat tgcagttatc aattgcactt actggaatag tttcagggtc gtacatcttt 15600 gtgtcaaata tagaaggaat ttcccaagcg ttgaaaattt caccgatgat tcttgcttta 15660 attattactc caattgctac tgaattacct gagaagttta acagtataat atggataagg 15720 aaaggaaaag attcacttgc actaggaaat attagtggtg caatggtatt tcaaagttgt 15780 atacctgtgg cggttggaat agtttttact acatggaagc ttaataatac tgctatggta 15840 agttgtgtat tatcattagt atcatctgtc attttgctgt tatggatgaa ggtaaagaag 15900 gaattaaccc cattaccttt tatattttgc ggtgtgttat atattttatt tattatttac 15960 ctgacaaatg gcgtatttca ttaa 15984 // |
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