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EBI DbfetchID AF166095; SV 1; linear; genomic DNA; STD; PRO; 4359 BP. XX AC AF166095; XX DT 22-JUL-1999 (Rel. 60, Created) DT 15-APR-2005 (Rel. 83, Last updated, Version 3) XX DE Klebsiella pneumoniae KAY 2026 D-mannitol uptake and degradation operon, DE complete sequence. XX KW . XX OS Klebsiella pneumoniae OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Klebsiella. XX RN [1] RP 1-4359 RX DOI; 10.1111/j.1574-6968.2001.tb09473.x RX PUBMED; 11164312. RA Otte S., Lengeler J.W.; RT "The mtl genes and the mannitol-1-phosphate dehydrogenase from Klebsiella RT pneumoniae KAY2026"; RL FEMS Microbiol. Lett. 194(2):221-227(2001). XX RN [2] RP 1-4359 RA Otte S., Lengeler J.W.; RT ; RL Submitted (07-JUL-1999) to the EMBL/GenBank/DDBJ databases. RL Biology, University of Osnabrueck, Barbarastr. 11, Osnabrueck 49076, RL Germany XX FH Key Location/Qualifiers FH FT source 1..4359 FT /organism="Klebsiella pneumoniae" FT /strain="KAY 2026" FT /mol_type="genomic DNA" FT /db_xref="taxon:573" FT CDS 294..2201 FT /codon_start=1 FT /transl_table=11 FT /gene="mtlA" FT /product="mannitol transport protein" FT /note="D-mannitol-specific enzyme IICBA" FT /db_xref="GOA:Q9XBM7" FT /db_xref="InterPro:IPR002178" FT /db_xref="InterPro:IPR003352" FT /db_xref="InterPro:IPR003501" FT /db_xref="InterPro:IPR004718" FT /db_xref="InterPro:IPR013011" FT /db_xref="InterPro:IPR013014" FT /db_xref="InterPro:IPR016152" FT /db_xref="UniProtKB/Swiss-Prot:Q9XBM7" FT /protein_id="AAD45385.1" FT /translation="MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLPN FT ETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVVGAITTMGVIVGADMPMFLGSMIAG FT PLGGYCIKKFDNWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPAVEVLSKILAA FT GVNFMVAHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIEANPG FT PGMGVLLAYMFFGRGSAKQSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILGGMTGV FT FTLTILNGGLVSPASPGSILAVLAMTPKGAYFANIAAIIAAMAVSFVVSAVLFKTSKVK FT ERSDIEAATRRMHDMKAESKGASPLAAGNVTNDLSHVRKIIVACDAGMGSSAMGAGVLR FT KKVQDAGLSNISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLTNFLDSGLY FT TSLTERLVAAQRHIDNEVKVTDSLKDSFDDTNNNLFQLGADNIFLGRKAATKEEANSFA FT GEQLVKGGYVEPEYVQAMLDREKLTSTYLGESIAVPHGTIEAKDRVLKTGVVFCQYPEG FT VRFGEEEDEVARLVIGIAARNNEHIQVITSLTNALDDETVIERLAKTTSVDEVLALLNK FT " FT CDS 2302..3450 FT /codon_start=1 FT /transl_table=11 FT /gene="mtlD" FT /product="D-mannitol-1-phosphate-dehydrogenase" FT /db_xref="GOA:Q9XBM6" FT /db_xref="InterPro:IPR000669" FT /db_xref="InterPro:IPR008927" FT /db_xref="InterPro:IPR013118" FT /db_xref="InterPro:IPR013131" FT /db_xref="InterPro:IPR013328" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/Swiss-Prot:Q9XBM6" FT /protein_id="AAD45386.1" FT /translation="MKALHFGAGNIGRGFIGKLLADAGIELTFADVNQTVLDALNARHS FT YQVHVVGENEQVDTVSGVNAVSSIGDEVVDLIAEVDVVTTAVGPVALERIAPAIAKGLA FT QRKAQGTERPLNIIACENMVRGTTQLKGHVFNALAEEDKAWVEAHIGFVDSAVDRIVPP FT SASATHDPLEVTVETFSEWIVDKTQFKGALPTIPGMELTDNLMAFVERKLFTLNTGHAI FT TAYLGKLAGHQTIRDAILDKKIRAVVQGAMEESGAVLIKRYAFDPQKHAAYIQKILGRF FT ENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHRNLVKGIAAAMHFRSEDDP FT QAQELAALIADKGPQAALAQISGLDAASDVVAEAVNDYNAEK" FT CDS 3450..4046 FT /codon_start=1 FT /transl_table=11 FT /gene="mtlR" FT /product="mtl operon repressor" FT /note="mannitol repressor" FT /db_xref="InterPro:IPR007761" FT /db_xref="UniProtKB/TrEMBL:Q9XBM5" FT /protein_id="AAD45387.1" FT /translation="MHNLARPTSRPLRLLSDMQAMMEETQAFENRVLERLNAGKTVRSF FT LIATVELLTEAVNILVLQVFRKDDYAVKYAVEPLLEGSGPLGDLSVRLKLIYGLGVISR FT AEYEDAELLMALREELNHDGNEYSFTDDEIIGPFGELHCVAALPPTPQFDDSDAELLAM FT QKLRYQQMVRSTMVLSLTELISRISLKKAFQKSTL" XX SQ Sequence 4359 BP; 1023 A; 1201 C; 1211 G; 924 T; 0 other; aaaacccgaa acaaaaatgt gacaaatatc acacaaaaag gcagatcagc ggctaaaaag 60 gcgctgtgtt gtttttttac acagtaattt tgtgatcatc atcactacaa aaccctctta 120 gccccctata ttcatgtgat ccaaatcaca taaaagggcg ctggctggac agctaaacga 180 ttcagtgcca gatttcgcac tatcaatcag ggcccggcta cctctgccgc cacattaaca 240 acaaacctcg ggctttaagc ctgcgcctac gcaaacagaa gaaggggtgt tttatgtcat 300 ccgatatcaa gatcaaagtg caaagctttg gtcgtttcct cagcaatatg gtgatgccga 360 atatcggcgc gtttatcgcg tggggtatca tcaccgcgct tttcattccg acagggtggt 420 tgccaaacga aacgctggcg aagctggtcg gtccgatgat cacctacctg ctgccgctgc 480 tgatcggtta caccggcggt aaattagtcg gcggcgaacg tggcggcgtg gtcggggcga 540 tcaccaccat gggcgttatc gtcggcgcgg atatgccgat gttcctcggc tccatgattg 600 ccggcccgct gggcggctac tgcatcaaga aattcgataa ctgggtagac ggtaagatca 660 aatccggttt tgaaatgctg gtgaataact tctccgccgg catcatcggg atgatcctcg 720 ccattctggc cttcctcggc atcggcccgg cggtcgaagt tctgtcgaaa attctggcgg 780 ctggcgttaa ctttatggtg gcgcacgaca tgctgccgct ggcgtctatc ttcgtcgaac 840 cggcaaaaat cctgttcctt aacaacgcca tcaaccacgg tatcttctcg ccgctgggta 900 ttcagcagtc ccacgagctg ggtaaatcca tcttcttcct gattgaagct aacccgggtc 960 cagggatggg cgttctgctg gcgtacatgt tctttggccg cggcagcgca aaacagtctg 1020 caggcggggc ggctatcatc cacttcctgg gtggtatcca tgaaatctac ttcccgtacg 1080 tgctgatgaa cccgcgcctg atcctggccg ttatcctcgg cgggatgacc ggtgtcttca 1140 ccctgactat cctcaatggc ggtctggttt ccccggcttc cccaggctct atcctggcgg 1200 tactggcgat gacgccgaaa ggcgcctact tcgctaacat cgccgcgatt atcgcagcga 1260 tggcggtctc cttcgtggtc tctgcggttc tgttcaagac cagcaaagtc aaagagagga 1320 gcgatatcga agccgcaacg cgtcgtatgc atgacatgaa agcggaatcc aaaggcgcca 1380 gcccgctggc ggccggtaat gtcaccaacg acctgagcca tgtgcgtaaa atcatcgtcg 1440 cctgcgacgc cgggatgggt tccagcgcca tgggcgccgg ggtactgcgc aagaaagtgc 1500 aggatgccgg gctgagcaac atctcggtca ccaacagcgc aatcaataac ctgccgccgg 1560 atgttgacct ggtcatcacc caccgcgacc ttaccgagcg ggcgatgcgc caggtgccgc 1620 aggcgcagca tatttcgctg accaacttcc tcgacagcgg tctgtacacc agcctgaccg 1680 agcgcctggt cgcggcccag cgccacatcg acaacgaagt caaagtcacc gatagtctga 1740 aagacagctt tgacgatact aacaacaacc tgttccagct gggcgcggat aacatcttcc 1800 tcggtcgcaa agcagccacc aaagaagaag cgaattcctt cgccggtgag cagctggtga 1860 aaggcggtta cgttgagccg gaatatgtgc aggcgatgct ggaccgcgaa aaactgacct 1920 cgacctatct cggcgagtcc attgcggtac cgcacggcac catcgaagcg aaggaccgcg 1980 tgctgaaaac cggcgtcgtc ttctgccagt acccggaagg cgtgcgcttc ggtgaagaag 2040 aagatgaagt cgcgcgtctg gtcatcggaa tcgccgctcg taataacgag cacattcagg 2100 ttatcaccag tctgactaac gcgctggatg acgaaaccgt gattgagcgc ctggcgaaaa 2160 ccaccagcgt cgacgaagtt ctggcactgt taaataaata atcagcgcta tccaaccctc 2220 tcctttggga gagggttggg gtgaggggaa aggcctcacc ccagccctct caggtgaaaa 2280 cattaattgg aggttaatac tatgaaagca ttacattttg gcgcaggtaa tatcggacgt 2340 ggctttatcg gtaaattgct ggccgacgcg ggcatcgaac tgacgtttgc cgatgtcaat 2400 cagaccgtac ttgatgccct gaatgcccgt catagctatc aggttcacgt cgtcggtgag 2460 aatgagcagg tggacaccgt ctccggcgtc aatgccgtca gcagcatcgg cgatgaggtt 2520 gtggacctga tcgctgaggt ggatgtggtc accaccgccg tcggtcccgt cgctctcgag 2580 cgcatcgcgc cagcgatcgc caaagggctg gcgcagcgca aagcgcaggg caccgaacgc 2640 ccgctgaaca tcatcgcctg cgaaaatatg gtgcgcggca ccacgcagtt aaaaggccac 2700 gtgtttaacg cgctggcgga agaagataaa gcgtgggtgg aagcgcatat cggctttgtc 2760 gactctgccg ttgaccgtat tgtgccgcca tcggcttccg ccactcatga cccgctggaa 2820 gtcaccgtgg aaacctttag cgaatggatt gtcgataaga ctcagttcaa gggcgcgctg 2880 ccgactatcc cggggatgga attaactgat aacctgatgg catttgtcga acgcaagctc 2940 ttcaccttga acaccgggca tgctataacc gcctacctcg gaaaactggc gggccatcag 3000 acgattcgcg acgcgatcct cgacaagaaa attcgtgccg tcgtgcaggg cgcgatggaa 3060 gagagcggcg cggtgctgat caaacgttac gcctttgacc cgcagaagca cgcggcttat 3120 atccagaaaa tacttggccg tttcgagaac ccgtacctga aagacgatgt tgagcgcgtt 3180 ggccgtcagc cgctgcgcaa actgagcgct ggcgaccgtt taattaagcc gctgctgggt 3240 accctggaat acgggctgcc gcaccgcaac ctggtgaaag ggattgcggc ggcgatgcat 3300 ttccgtagcg aagacgatcc gcaggcgcag gagctggcgg cactgatcgc cgacaagggg 3360 ccgcaggccg cgctggcgca gatttccggc ctggatgccg caagtgatgt cgtcgcggag 3420 gccgttaacg actacaacgc ggaaaaatga tgcacaacct ggcgcggccg acgtcgcgcc 3480 cattacgact cctgtcagat atgcaggcaa tgatggaaga aacacaagca tttgaaaacc 3540 gtgtgcttga gcgtctgaat gctggcaaaa ccgtacgaag ctttctgatc gccaccgtcg 3600 agctgttaac ggaagcggtc aatattctgg tgcttcaggt gttccgtaaa gacgactacg 3660 cggtgaaata cgccgtcgag cccttgctgg agggcagcgg gccgctcggc gatctctctg 3720 tacgcctgaa gctgatttat ggccttgggg tgataagtcg tgccgaatat gaagacgctg 3780 agctgctgat ggccctgcgt gaagagctta accacgacgg caatgagtac agctttaccg 3840 acgacgaaat tatcggtccg ttcggcgaac tgcactgcgt cgccgccctg ccgccaacgc 3900 cgcaatttga tgacagcgat gccgaactgc tggcaatgca gaaactgcgt taccagcaga 3960 tggtgcgctc aacgatggtg ctgtccctga ctgagctgat ttcacgaatc agcttaaaaa 4020 aagcctttca gaaatcaacg ctctgattcc ggttccgtct ggtcgcaggt cggccggtaa 4080 agctgacgat aatattccag acgctgcaga cgcggagact ttttcaaata ctccataaac 4140 gcctgactgg cagccataaa atcaaccgct ttgtcgatta aacgtggtac gccgtcgccg 4200 atctttgcca tcacgtcctc cttttgggaa taatctgatt aagcattagc caattcaccg 4260 gcgtgggtta aggaaaacgt gcttatcgac cgacagcttt cacagaaatg aaattagaac 4320 gggtaattag gcggaatatt attaaattca aattatagc 4359 // 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