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EBI DbfetchID AF141924; SV 1; linear; genomic DNA; STD; FUN; 12000 BP. XX AC AF141924; XX DT 03-JUN-1999 (Rel. 59, Created) DT 03-JUN-1999 (Rel. 59, Last updated, Version 1) XX DE Aspergillus terreus lovastatin biosynthesis gene cluster, partial sequence. XX KW . XX OS Aspergillus terreus OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; OC Aspergillus. XX RN [1] RP 1-12000 RA Kennedy J., Auclair K., Kendrew S.G., Park C., Vederas J.C., RA Hutchinson C.R.; RT "Accessory Proteins Modulate Polyketide Synthase Activity During Lovastatin RT Biosynthesis"; RL Science 0:0-0(1999). XX RN [2] RP 1-12000 RA Hutchinson C.R., Kennedy J., Park C.; RT ; RL Submitted (09-APR-1999) to the EMBL/GenBank/DDBJ databases. RL School of Pharmacy, University of Wisconsin, 425 N. Charter St., Madison, RL WI 53705, USA XX DR StrainInfo; 412432; ATCC 20542. XX FH Key Location/Qualifiers FH FT source 1..12000 FT /organism="Aspergillus terreus" FT /strain="ATCC20542" FT /mol_type="genomic DNA" FT /db_xref="taxon:33178" FT CDS complement(join(1813..2301,2372..3332,3511..4774, FT 4822..5520,5584..6462,6568..6865)) FT /codon_start=1 FT /product="esterase" FT /note="ORF1" FT /db_xref="GOA:Q9Y7C6" FT /db_xref="InterPro:IPR001087" FT /db_xref="InterPro:IPR013517" FT /db_xref="InterPro:IPR013830" FT /db_xref="InterPro:IPR013831" FT /db_xref="UniProtKB/TrEMBL:Q9Y7C6" FT /protein_id="AAD34550.1" FT /translation="MASLLFFTVFNLTLALLSSTATGAAVPVSRPTDDSRYIDFDAAEW FT RPRAKRDDALKVPLRILPLGASITWGYLSSTGNGYRKPLRDKLRFEGWEVDMVGKAHSG FT DVITQVQTAAANSLAYKPNVVLINAGTNDCDYNVDPANAGERMRSLIETLIGAPDMANT FT LIVLSTLIPSGSTTLEANRPSVNAQFRELVLDMREAQNVSIVLADMDPPAPSPGNNWIT FT YPDNFADNKHPNDYGYSQMADIWYNAIYNAAVAELIVKPADLDISSTGTCDKEYGSGVY FT AGGFTQQGSGEDDGIYRHDSEYSGALFTVRAGKGAADPYKDDDELHFFFGRLYTRAYDD FT MMIFHKDKDSGAVTFVSYTNNVHTEEQEFTKGGTFSTHNNCNPGGVHFIDINGDGLDDY FT ICIALDGTTYASINNGDGDAKSNKPPSFTDIGLWKSPEGYDQAHVRLADIDGDGRADYC FT GLADNGDVTCWRNGWIEDIPAYWQPLGKRFTGKVMGDLRGVRFEDINGDGRDDWMWVDD FT DGATTTYTNSRSCIKGESGDGLNVVWRQGFYQDANSGPSHPGMGVIFGTSGLRDQVYFA FT RLYGEVADFGELGRQDYVFIKKDTSDKYFGPLYYVHVWKSKGAGGAKIKADGDRYCNMM FT GHDNGMMDYIWIHSTGHMRLYPNRGLVEVPADGSSFWGANEIIFDPQEQIGMKLDRRDL FT HLADWDGDGACDIIWTDPDNLNRAQVWRNKIKDTGSFDWDYNINAADELYCPEHRGLGF FT FDRPVHFADVSGNGKADYLCVEKDGRTWGWVNGDDGWDYIDQFKYSEEKDRANLHWADV FT NGDGKADMIWTDKFSGDGSVWYNLGQRDIKGSRYEWGPQGPKYRGAVEGSCTYFPDLNG FT DGRADMHSIWNSINNTAQTWYNECATKDHTGDDGPITNPNLPVSPVKAPIELTPHYQDN FT SECTRAQVQTLFEEMQYALDAASEVAYFSGGAYDPYRDIFFAESLTDSLTFTINVRYTF FT DRMVTMISGSSQFDDEKFTITCKNLRGCDENGWLAMMNNRNRLNFCPKFFTDELKSSRR FT TRDYVYGWKGARDLAAGTFNRHCIERGRKAERAANELRIAGDANWQRRLLCPDPNNLGQ FT EGICDSKLSAYNADSWALVVLGGYYTKICGRQIPLPEESASSADDSSCPAYDDSSYDAD FT TVYGVNDYVHFGDSYAAGMGTGTTTGDSCRVGSNSYGKLVQEWFDTEDFTYTNYACSGD FT TTVGLNKKIDQWLGQDPTGTTMATLTIGGNDVFFSDLVSNCVLTMWWYSLEQYRQWCLE FT TEEKARNLMQDTGSDGLGSKLRAAYEKILDRSGSSVYLPVILIYSCRAVLRRADFTLVV FT QPLRPWLCHLLQRRHHRLRLNHLLELNDLVRMLNSLIQSTISDINTARNTEQIHYIDMD FT ARFDGHRWCEPGTQEPDPDNPNTYFFLSAWPDIAIVGDTTAESTNATETDEITALMNSG FT SIQLPDADTCQDALGSDPDPYAVFMCDVAVHVKANSSSLIAQSLDRANQAIANRDYSSQ FT DVSWWLPSP" FT CDS 7616..8602 FT /codon_start=1 FT /product="unknown" FT /note="ORF2" FT /db_xref="UniProtKB/TrEMBL:Q9Y7C7" FT /protein_id="AAD34551.1" FT /translation="MTLPTLPNWIRMCVHLSLTHLHQHRSPKYESIPIKSIQANSHRIL FT IILTTASFYPQIRCIQLRNSTHGISTAYILFNLISATEHFTILFALLVNSGGDVLIHEP FT PTTGDGLNLYQLFAVWMGCLVLFCQAIHSLHANPRRKLILLTIYIQYLCISILPEVIDA FT ITTPEETRKQRPPTGERNWLIGLFLSAHAMTVLPLSAVLRIAGFIDQSRLISRRRREQP FT SVLSLTGLACQAVVFALVSGLWVLRVQQPVPRMPMRRPVDWMYWYHVIGWPVVDDAVYA FT LGQWVLFWYAVCWRSRGDARDEAVHAGETDDLLGEDEGHGYGGTGTS" FT CDS complement(join(9980..11016,11089..11260,11335..11712)) FT /codon_start=1 FT /gene="lovA" FT /product="cytochrome P450 monooxygenase" FT /function="involved in lovastatin production" FT /db_xref="GOA:Q9Y7C8" FT /db_xref="InterPro:IPR001128" FT /db_xref="InterPro:IPR002401" FT /db_xref="UniProtKB/TrEMBL:Q9Y7C8" FT /protein_id="AAD34552.1" FT /translation="MTVDALTQPHHLLSLAWNDTQQHGSWFAPLVTTSAGLLCLLLYLC FT SSGRRSDLPVFNPKTWWELTTMRAKRDFDANAPSWIESWFSQNDKPIRFIVDSGYCTIL FT PSSMADEFRKMKELCMYKFLGTDFHSHLPGFDGFKEVTRDAHLITKVVMNQFQTQAPKY FT VKPLANEASGIITDIFGDSNEWHTVPVYNQCLDLVTRTVTFIMVGSKLAHNEEWLDIAK FT HHAVTMAIQARQLRLWPVILRPLVHWLEPQGAKLRAQVRRARQLLDPIIQERRAERDAC FT RAKGIEPPRYVDSIQWFEDTAKGKWYDAAGAQLAMDFAGIYGTSDLLIGGLVDIVRHPH FT LLEPLRDEIRTVIGQGGWTPASLYKLKLLDSCLKESQRVKPVECATMRSYALQDVTFSN FT GTFIPKGELVAVAADRMSNPEVWPEPAKYDPYRYMRLREDPAKAFSAQLENTNGDHIGF FT GWHPRACPGRFFASKEIKMMLAYLLIRYDWKVVPDEPLQYYRHSFSVRIHPTTKLMMRR FT RDEDIRLPGSL" XX SQ Sequence 12000 BP; 2949 A; 2942 C; 2995 G; 3114 T; 0 other; tggattttct tcctgtaggc ccgtagctat gtaatctagc taaacagagc gcgtatttta 60 aatattagaa actgctcgcg tatcttatcc agagcgttag ctaggtaggt tacctggtct 120 gttttagcaa gctggacggc ctgcagggcg actaatattt aggctatttt tataagcccg 180 gaaagatagc ttatatagct ataaggcttt agaaagatct actgcttaat atctatttct 240 aaaataataa gaaatctaat aagagtactt ttaaagagat ctttcttaag agtatggtcg 300 agtaagataa ttaaaaatat taaacaggcc taattaagca gttctttagt ttgctgctgc 360 tgattaacgc gctacaatag tttaagatct tagctttaga ttaggagatt aactagctgc 420 cggctataaa tttttatcta attaagcgcg gtaaactagg cagtatttag ctagtggcgg 480 agtaaaatta gctggttagt ccggctacta tggtaggcga agtaaataag acactgctag 540 atctagtagt actaacagta cgtcgctagc cgtagataga tctagattag ctggttttag 600 atccccggcc ggcggaagaa gatattaatc taaatttagt tgaatttatt aatccggccc 660 ttcttaatcg cgtaataggt ctaattaatt agttgctgga cgctagcagt aaattacttt 720 agtaaagatt tagctatagg attagaaaag ctgccgagta gggcgactgc ggtttaatct 780 taattataaa ggtattccgg ctattaaata agctctagct ataaggaaat tgtagttaga 840 tgtagattaa taatagagat ctagtcgtta gtcctatccg cggtagccta atttttttat 900 aaagcctgct cgacccgagc ctgaataatt atagctaagg tctttagaga gacggctttc 960 tctagtcttt aattagaaga ggcctcggta tatattactt taaagaatta actagtagat 1020 tagctgataa agaagcgctg atagctaata atatactctg ttagtcgggc gcgaagccta 1080 gcttatattt aagtaatagt cttctaactc tattttcttc gtgccctatt ataattagta 1140 tagttttaat tttaatattt atttattgtc tgtcggcact aatagatata tttataatat 1200 aggcagctat aactacggta gactggaaga cctaaaatca gagagctact tagagggggg 1260 aaataaataa tctcctactt tagattaatt tagagctgct gaagtattac agttaaagca 1320 gcttgttaga gggccggaat agtggtatta gaataaaagc tataacgcgt ttggaggtag 1380 ataataaaag tagtagaaga aactatatac tagtaggaag gtgtagtata gatctagatc 1440 ttataggtta agttatagag aaagagctct attgttaatt ctaggctcta agagaaaagt 1500 acctagagag ttaagaataa aggaaaatag gtttctataa ggagctattt tctttttaat 1560 atttattata ttttttaaag atatattaat ggcgcgtcgg atacacgtag taaaaagtaa 1620 attcgtgtct gctattgctt attcctgaag ataaaatata gatataatct cgctaggtcc 1680 tctttaaata agatagaacg gcggagctgt ctgttcgggg cacgcatgta aggcgacggg 1740 agcacggcga aatattaaat cttgaccaat tagcaggcga gaaaatggat cgaaggttgg 1800 gtgaacttgg gcctagggac taggcaacca ccaagagaca tcctggctac tatagtccct 1860 attggcaatg gcctgattcg ctcggtccaa gctctgcgcg atcaaactcg acgagttcgc 1920 cttgacgtgg accgcaacgt cacacatgaa aaccgcatag ggatccgggt cagatcccag 1980 cgcatcctgg cacgtatccg catcgggcag ctggatcgat ccggagttca taagcgcggt 2040 aatttcgtct gtctcggtcg cgttcgtgct ctcggctgtc gtgtctccaa caatcgcgat 2100 atcgggccat gcggatagga agaagtaagt gtttgggttg tcggggtctg gttcttgggt 2160 tccgggctcg caccagcggt ggccgtcaaa tcgcgcgtcc atatcgatgt aatggatctg 2220 ctccgtattc cgggcggtgt tgatgtcgga aatggtggat tggattaacg agttgagcat 2280 gcggacgagg tcgttgagtt ccttgcgtag gtcggtcgtg agccacacat agttgccgga 2340 ttgctgcggg tcgtagtgtg ggctttcgta ccagaaggtg gttgagtcgc agtcggtggt 2400 gtcttcgttg aagaaggtga catagccagg gacgtagagg ttgaacgact aaagtaaagt 2460 cagcgcgacg aaggacagca cgacaggaat aaataaggat aacagggaga tatacgctag 2520 agccagatct atccaggatc ttttcatacg cagccctaag tttcgagccg agtccgtcag 2580 accctgtatc ctgcatcagg ttgcgggctt tctcttcagt ctccagacac cactggcggt 2640 attgctcaag cgagtaccac cacattgtta gcacgcagtt ggaaaccaga tcgctgaaga 2700 acacatcgtt ccctccaatt gtcagggttg ccatggtagt ccccgtgggg tcctgtccta 2760 gccactggtc gatcttttta ttcagcccaa ccgttgtatc tccagagcac gcatagttgg 2820 tataagtgaa atcctcagta tcaaaccact cctggacgag ctttccgtag ctgttacttc 2880 ccacgcggca actgtcaccg gttgtggttc ctgtacccat cccagcggcg taggagtcac 2940 cgaagtgaac ataatcgttg acgccgtaca cagtgtcagc atcataagac gaatcatcgt 3000 aggccggaca gctggagtca tccgccgaag aagcagactc ctcaggaagg ggaatctgtc 3060 gaccacatat cttggtatag tacccgccaa gtacgacaag agcccatgaa tccgcattgt 3120 aggcggacaa cttgctgtca cagatgcctt cttgcccgag gttatttggg tctgggcaaa 3180 gcaatctgcg ttgccagtta gcatcgccgg ctatacggag ctcattagcg gctctttcag 3240 cctttctgcc tctttcgata cagtgtcgat tgaaggtccc tgcggcaaga tctcgagctc 3300 ctttccatcc atagacataa tcgcgggtcc tcctaaggtg aaagaatcag tatcggcctg 3360 ggaatgagaa aaaatatgtg ataccaccca ttctctccat tgacaatctc cataacatag 3420 tccgtatgcg ttacttcgtg caaaatcgcc ccggctcgag tgagatgggc atcatgaaga 3480 ttaattgagt cgcacctcgc gagcactgac ctggaactct tcaactcatc tgtgaagaac 3540 tttgggcaga aattaagccg attcctattg ttcatcatgg ccaaccagcc gttctcgtca 3600 cagccccgaa ggtttttgca agtgatcgtg aacttttcgt cgtcgaattg cgaagaccca 3660 gaaatcatgg tgaccatccg gtcgaacgta taccttacat ttatagtgaa ggtcaagctg 3720 tcggtgagtg attcggcaaa gaagatgtcc ctatatgggt cgtatgcgcc gccgctaaag 3780 tacgcaactt ccgaggcagc atcaagcgca tattgcattt cttcaaagag cgtctgcacc 3840 tgggccctag tgcactcgct gttgtcctga taatgagggg tgagctcgat gggggctttt 3900 acaggagata caggtagatt ggggttagtt atcgggccgt catcgcctgt gtggtctttg 3960 gtggcacatt cgttgtacca cgtctgcgct gtgttgttta tggagttcca gatgctgtgc 4020 atgtctgcac gaccgtcgcc gttcagatca gggaaataag tgcatgagcc ttcaaccgcc 4080 cctcggtact tgggaccctg cggtccccat tcgtatcgcg atcccttgat atcacgttgg 4140 ccaaggttgt accacaccga cccatctccc gagaacttgt ctgtccagat catatcggcc 4200 tttccgtcgc cgttgacgtc ggcccagtgt agattcgccc tgtccttctc ctcggagtac 4260 ttgaattgat caatgtagtc ccatccatcg tccccattga cccagcccca ggtgcggccg 4320 tccttctcaa cgcacagata atcggccttg ccgttgccag aaacatcagc aaaatggacc 4380 ggccggtcaa agaaaccaag gcctcggtgc tcggggcagt aaagctcatc tgcagcattg 4440 atattgtagt cccagtcaaa actccccgtg tctttgatct tgttccgcca aacttgggcc 4500 ctgttcagat tgtcgggatc cgtccagatt atatcgcagg ctccgtcgcc gtcccagtct 4560 gcgagatgca gatcgcgccg gtcaagcttc atgccaatct gctcttgggg gtcgaagata 4620 atctcattcg ccccccagaa gctcgacccg tcggcgggga cttcaaccag gcccctattc 4680 ggataaagac gcatatggcc ggttgaatgg atccaaatgt agtccatcat accattgtcg 4740 tggcccatca tattgcaata cctgtctccg tcggctataa caattagcaa tcaacctctc 4800 tatgagaact tccttccata cctttgatct tagcccctcc tgcgcccttg ctcttccaca 4860 catgaacgta atacagcggc ccaaaatact tgtcagaggt atccttcttg atgaacacat 4920 agtcctgtct cccgagctct ccaaaatccg ccacctcgcc atagagtcgc gcaaagtaga 4980 cctgatcccg taatccggat gtcccgaata ttactcccat tccgggatgc gacgggccag 5040 agttagcatc ttggtagaac ccctggcgcc acacgacgtt caacccgtca ccagactctc 5100 ctttgatgca gctccgggag ttggtgtatg ttgtcgtagc gccatcgtca tcaacccaca 5160 tccagtcgtc gcgcccgtcg ccgttgatat cctcgaatcg cacgccgcgc aggtctccca 5220 tgactttccc cgtgaagcgc ttgcccagcg gctgccagta tgcggggata tcttcgatcc 5280 atccatttcg ccagcatgtg acgtcgccgt tgtcagccaa accgcagtag tcggcgcggc 5340 cgtcgccgtc gatatcagca aggcgtacat gtgcctgatc gtatccttcg ggactcttcc 5400 atagtccgat atcggtgaag gatggaggct tgttgctctt ggcgtcgccg tctccattgt 5460 tgatgcttgc gtaggtggtc ccgtccaagg cgatgcagat gtagtcatca agtccgtcgc 5520 ctatcattta tcacacataa atcagtccca gatggttcct cggcagacag acacagtgct 5580 taccgttgat gtcgataaaa tgcacacccc ccgggttaca attattatga gtcgagaacg 5640 tccccccctt cgtaaactcc tgctcctcag tgtggacatt attcgtgtaa gaaacaaacg 5700 tcaccgcgcc ggagtcctta tctttgtgga agatcatcat gtcatcatac gccctagtat 5760 aaagcctccc gaagaaaaag tgcagctcgt cgtcatcctt gtatggatcg gctgcaccct 5820 tcccggcgcg gacagtaaac aacgccccgc tatactcgct gtcgtgtcga tagattccgt 5880 catcctcacc actcccttgc tgcgtgaacc cgccagcgta gactccgctc ccgtactctt 5940 tgtcacaggt ccccgtggat gagatgtcaa ggtccgccgg cttgacaatg agctccgcca 6000 ccgcagcgtt gtagatcgcg ttataccaga tgtctgccat ctgggagtac ccgtagtcgt 6060 tggggtgctt gttatcggcg aagttatcgg ggtacgtgat ccagttgttt ccggggctgg 6120 gagccggcgg atccatatcg gccaggacga tggagacatt ctgcgcctcg cgcatgtcaa 6180 ggaccagctc gcggaactgc gcgttgacgg agggcctgtt agcttcgagg gttgtggaac 6240 ccgaggggat cagggtcgac aggacgatga gcgtgttggc catgtccggg gcgccgatta 6300 gggtttcgat cagggagcgc atgcgctcgc cggcgttcgc agggtcgacg ttgtagtcgc 6360 agtcgttggt gccggcgttg atcagcacga cgttcggctt gtaggcgagc gagtttgcgg 6420 ccgcggtttg cacttgcgtt atcacgtcgc cgctgtgggc ttctacatcc ttttcccgcg 6480 tttatatgtc aattggtctg tctatctgtc ggaggggtgg gggaagagag atgcatacat 6540 tgtctaccat gtcaccgttg gacttactgc ccaccatgtc cacctcccag ccttcaaagc 6600 gaagtttgtc acggagaggt ttgcgatatc catttccggt tgaggatagg tatccccagg 6660 tgatggatgc gccaagaggg aggatccgta gagggacttt cagggcatca tctcgttttg 6720 ctcttggacg ccattcagca gcgtcaaagt ctatatatct cgaatcgtct gtgggtcgcg 6780 agacagggac ggctgctcct gtggcagtag atgatagaag agccagtgtt agattgaaca 6840 ccgtaaagaa aagtagagac gccattatcg atgctgactc tctgcacctt tcactcctct 6900 tccatactgc gagtcgcttt tatactttca cagccctcca gtcatttcat gtgtaagatg 6960 cctcggcgta tgtgccgttc tgaaacaagt gtacttccaa gaatcgcgag ctcgagtatg 7020 gtaccaggat aaacctggat acttaggtat caaagcatga gaccctggca tttttcatgg 7080 caagtttggg ggccataatc ctgtggcaga ggttcatatg cggcggtcga gtcatgcaat 7140 gggtttattt ggcgtagttt acggagcaac caatcactgg cctgaatatg gtaccaggat 7200 gaaccagaat agtaccaaag gatgagactg gcatccttca tagccataac tgttgggggt 7260 catcatctgt gacagggaga tatgcagtga ttgagtggtg caacgggctt aaatgtaatc 7320 ggtgtttgca actacgcgga gtgctaggga ggcggctgat tggcatgata agcaaaggct 7380 tagctgagac atggcactag gtagaggcta ggacctgcgt aagcattcat tccgatgctc 7440 tattggataa gttatttaca atctccgcat taggcggcaa tccttaatat agaatactag 7500 tatagagcac tatggacact ccgacgttca tttaatatct ccacccgtgt tacccctctt 7560 tctgcctttg atctctatca agctggccct tctggcattt atccttgcat taaacatgac 7620 tctaccaaca cttcctaact ggataaggat gtgcgtgcat ttgtccctta cacatctcca 7680 tcagcaccgt tccccgaaat acgagtctat acctattaaa agtatccagg ctaattcaca 7740 cagaatcctc atcatcctaa ccacagcctc cttctacccg cagatccggt gcatccaact 7800 tcgaaactcc acgcacggca tctccactgc ctacatcctc ttcaacctaa tcagcgcaac 7860 agaacacttc accatcctat tcgcattgct ggtaaacagc ggcggagatg tcctcatcca 7920 tgagcccccc acgaccggcg acgggttgaa cctgtaccag cttttcgcag tgtggatggg 7980 atgcttagtc ctcttctgcc aagcaatcca tagcctccac gccaatccac gccgcaaact 8040 catcctacta accatataca ttcaatacct atgcatttct atcttaccag aggtcatcga 8100 cgcaatcacc actcccgagg aaacgagaaa acaaaggccg ccaacgggcg agaggaactg 8160 gctgatcgga ctctttcttt ccgcgcacgc gatgaccgtc ctgccactat cggccgtgct 8220 ccgcatcgcg ggattcatag atcagtcgcg actgatctcg cggcgcagac gggagcagcc 8280 atcggtctta agcctgacag gcctggcgtg tcaggccgtg gtctttgctc tagtttctgg 8340 actctgggta ctcagggttc agcagcctgt tcctcgaatg ccgatgagaa gacctgtgga 8400 ttggatgtat tggtaccatg taattgggtg gccggttgtc gacgatgcgg tttatgcgct 8460 gggacaatgg gttttgtttt ggtatgcggt ttgttggcgt tctcggggcg atgctaggga 8520 tgaagcagtc catgctgggg agactgatga cctgttagga gaggatgaag ggcatgggta 8580 cggcggaacc gggacttctt agattgtctg tatatcattg tgccacgata tcgcgtgtaa 8640 caccatggtg tggaaggtat actcatcgcc atggattttt tgacaagctt gctataatag 8700 ctcttggtta actcttttgc ctttttttat tctgccatac ggtctcattc agagcacgat 8760 ctgcagggga aagagaacag ctataccgtc gcatgatttc aaccttccaa actcttatta 8820 tcaaactggt aatagcaccg tgaatgggat ggcttaggct ttagatgaag gagttagagc 8880 ctggctgcaa gccctaaaca cctgtctagt ccacgttata atttagcaag tctcccgagc 8940 tctcgcaagc ctaccactag cttatagtca atagattgtg gtatatccag gggcctttta 9000 agtatttacg gctcatacaa aaagtaatat gagacagctc tactcttttt acatcatcta 9060 catctatcgc ctagattggt agctcgcagt gggtcatccc tatctgttac cataagactt 9120 cccgtggtcg caattcaacc taatgcagga ctttctcgtg ggccgattta ttactagacc 9180 tattgatctt tgattgtggc ttcatccggt cgctattact tacagccaca gtgatcatag 9240 tattcgaatt acaatgttga acctctgcca cgattactat caggtccttc tagttggacc 9300 tctctccacc agcgttgaag tataatcccg tagactcaaa aaccaacccg acctgatcca 9360 ataccaagtc taattataat cagaaaaaaa tattttaaaa attaaaattt atatagatat 9420 ctgctaatcc tcgcagacta tatataagaa acccgtaatc tgcgcggact atagtagtat 9480 agattttagg acccgctccg cgcggagcgg agcggactgt ggatctgcgg agagttagta 9540 tacaaaatac tagaggcggc gaggtcgagt tagcgcagtc tagtactaaa taggaaagcg 9600 gttattttag cgcgaaaaca gggtactaat atttttggac ccccactgta ccttcacgga 9660 tagtaccaca caactacatt acgattatat atcatctttc cccctcccat ggttttccca 9720 agcaccttac acgtggccgc cctcaactac ctagtttgtt gacagaagtg cagtaacagt 9780 gacctaactg agtgtagttt agagatatat attctactat agggggctaa accgtggtgg 9840 attacgcaga ctttttgcta aaagcataat agctacgata ggtagaatat aactatagat 9900 aaggtagatt agggtaggta cgactgcggc ggcttgatta ttccttgaaa atgacgggct 9960 cttctggggt agactactgc tatagtgaac caggaaggcg gatatcctcg tcgcgccggc 10020 gcatcatgag cttcgtggtg ggatgaatgc gcacgctgaa agaatggcgg tagtactgca 10080 acggttcgtc ggggaccacc ttccagtcgt atcgtatgag caagtaggct aacatcatct 10140 tgatctcctt agaggcaaag aaccggccgg ggcaagcccg tggatgccaa ccgaagccga 10200 tgtggtcccc gttggtgttc tccagttggg cactgaacgc tttagccggg tcctctcgca 10260 ggcgcatata ccggtaagga tcgtattttg ccggctctgg ccagacctcg gggttgctca 10320 tgcggtcggc agctaccgcc accagctctc cttttgggat aaaggttcca ttggagaaag 10380 tcacatcctg caatgcatag ctgcgcatgg tggcacattc gacgggcttg acgcgctgtg 10440 actccttgag acaactatcc agcagtttga gcttgtacag cgaggcaggt gtccaacccc 10500 cttggccgat gaccgtccgg atctcatcac ggaggggctc aaggagatgg ggatgtcgga 10560 cgatgtccac caacccaccg atcagcaggt cggaggttcc gtagatacca gcaaagtcca 10620 tggccagttg cgccccggct gcatcgtacc atttcccctt ggcagtatcc tcgaaccact 10680 ggatcgagtc tacgtagcga ggcggctcaa tgccctttgc ccggcaggca tctctttccg 10740 cacgtcgctc ctggataatg ggatcgagaa gttgccgggc tcgtcgaacc tgcgcccgga 10800 gtttggctcc ctggggctcg agccaatgta caagggggcg cagaatgacg ggccagaggc 10860 gcagctggcg cgcttgaatt gccatcgtca ccgcgtggtg cttggcgatg tcaagccact 10920 cctcattatg ggctaacttg ctcccgacca taataaaagt cactgttcgg gtcactaagt 10980 ccagacactg gttatagaca ggcactgtgt gccattctga aagcaaaagc acatccctct 11040 tcatcagcta atggcctaaa aacaaaaata ctcatcatga tcacttacca ttgctgtcgc 11100 caaaaatatc cgtgataatc ccgctggctt cattggcaag aggcttgacg tacttgggag 11160 cttgggtctg gaactggttc ataaccacct tggtgatgag atgtgcatcc ctcgtgactt 11220 ccttgaatcc atcgaatccg ggaagatgag agtgaaagtc ctgatgagag cacgaagatc 11280 agtaagtcag gtcctcacag cggaagcagt tgcaaagaac ggtggactcc ttaccgtgcc 11340 caagaacttg tacatacaga gctctttcat cttgcgaaac tcatcggcca tagaggaggg 11400 aagaatggtg cagtacccag agtcgactat gaaccgaatg ggcttatcat tttgcgagaa 11460 ccagctctca atccatgacg gtgcattcgc atcaaaatcc cgtttggccc tcatggtcgt 11520 cagttcccac catgttttcg gattgaacac cggcagatca gatctccggc cactcgagca 11580 caggtaaaga agaaggcata gtagccccgc actggtagtg accaagggcg caaaccacga 11640 gccatgttgc tgcgtgtcat tccaagccag cgacagaagg tggtgcggct gtgtgagcgc 11700 gtcgacagtc atggctagga gaccaggtgt ggttgaggga taagatatcg agagtgatgt 11760 gagcaaaaga tccgggaaag gtcgcgaagg aaagggcgtc tctcttacca agaaagtctg 11820 ttccctatca tgcaatcacc gcttgctgta cggtggtgat gatgctggga tggtggtggg 11880 tccccaccga ataacgccgg acagctgttg aagccgaatg acgccggcag gccaaaagaa 11940 ccctaccttc acttactcaa tcggcgcttc ccctcctatc accaaatcgg atgtaaatgg 12000 // |
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