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EBI DbfetchID AF125322; SV 1; linear; genomic DNA; STD; PRO; 15943 BP. XX AC AF125322; L04596; U23775; XX DT 20-JUL-1999 (Rel. 60, Created) DT 01-OCT-2005 (Rel. 85, Last updated, Version 4) XX DE Escherichia coli O7-specific lipopolysaccharide biosynthesis gene cluster, DE complete sequence. XX KW . XX OS Escherichia coli OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Escherichia. XX RN [1] RP 11663-15943 RX PUBMED; 7677991. RA Marolda C.L., Valvano M.A.; RT "Identification, expression, and DNA sequence of the GDP-mannose RT biosynthesis genes encoded by the O7 rfb gene cluster of strain VW187 RT (Escherichia coli O7:K1)"; RL J. Bacteriol. 175(1):148-158(1993). XX RN [2] RP 1-15943 RX PUBMED; 7559340. RA Marolda C.L., Valvano M.A.; RT "Genetic analysis of the dTDP-rhamnose biosynthesis region of the RT Escherichia coli VW187 (O7:K1) rfb gene cluster: identification of RT functional homologs of rfbB and rfbA in the rff cluster and correct RT location of the rffE gene"; RL J. Bacteriol. 177(19):5539-5546(1995). XX RN [3] RP 1-15943 RX DOI; 10.1046/j.1365-2958.1996.01531.x RX PUBMED; 8971705. RA Marolda C.L., Valvano M.A.; RT "The GalF protein of Escherichia coli is not a UDP-glucose RT pyrophosphorylase but interacts with the GalU protein possibly to regulate RT cellular levels of UDP-glucose"; RL Mol. Microbiol. 22(5):827-840(1996). XX RN [4] RP 1-15943 RX DOI; 10.1016/S0966-842X(97)82912-5 RX PUBMED; 9004408. RA Reeves P.R., Hobbs M., Valvano M.A., Skurnik M., Whitfield C., Coplin D., RA Kido N., Klena J., Maskell D., Raetz C.R., Rick P.D.; RT "Bacterial polysaccharide synthesis and gene nomenclature"; RL Trends Microbiol. 4(12):495-503(1996). XX RN [5] RP 928-1300 RX PUBMED; 9620955. RA Marolda C.L., Valvano M.A.; RT "Promoter region of the Escherichia coli O7-specific lipopolysaccharide RT gene cluster: structural and functional characterization of an upstream RT untranslated mRNA sequence"; RL J. Bacteriol. 180(12):3070-3079(1998). XX RN [6] RP 1-15943 RX PUBMED; 10517601. RA Marolda C.L., Feldman M.F., Valvano M.A.; RT "Genetic organization of the O7-specific lipopolysaccharide biosynthesis RT cluster of Escherichia coli VW187 (O7:K1)"; RL Microbiology 145(Pt 9):2485-2495(1999). XX RN [7] RP 11664-15943 RA Valano M.A.; RT ; RL Submitted (27-JUL-1998) to the EMBL/GenBank/DDBJ databases. RL Microbiology and Immunology, University of Western Ontario, London, Ontario RL N6A 5C1, Canada XX RN [8] RP 1-4844 RA Valano M.A.; RT ; RL Submitted (13-OCT-1998) to the EMBL/GenBank/DDBJ databases. RL Microbiology and Immunology, University of Western Ontario, London, Ontario RL N6A 5C1, Canada XX RN [9] RP 1-15943 RA Valvano M.A., Marolda C.L.; RT ; RL Submitted (01-FEB-1999) to the EMBL/GenBank/DDBJ databases. RL Microbiology and Immunology, University of Western Ontario, Dental Sciences RL Building, Rm3000, London, Ontario N6A 5C1, Canada XX CC On or before Jul 18, 1999 this sequence version replaced gi:415622, CC gi:2749900. XX FH Key Location/Qualifiers FH FT source 1..15943 FT /organism="Escherichia coli" FT /strain="VW187" FT /serotype="O7:K1" FT /mol_type="genomic DNA" FT /db_xref="taxon:562" FT gene 22..948 FT /gene="galF" FT /citation=[3] FT /experiment="experimental evidence, no additional details FT recorded" FT CDS 22..930 FT /codon_start=1 FT /transl_table=11 FT /gene="galF" FT /product="GalF" FT /function="regulatory subunit of the UDP-glucose FT pyrophosphorylase" FT /db_xref="GOA:Q46768" FT /db_xref="InterPro:IPR005835" FT /db_xref="UniProtKB/TrEMBL:Q46768" FT /citation=[3] FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="AAC63611.1" FT /translation="MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIPVDKPMIQYIVDEI FT VAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNVR FT QGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRSQV FT LAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLSADI FT WPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYGLRN FT LKEGAKFLKGIEKLLSEVTNS" FT terminator 928..948 FT /gene="galF" FT /inference="non-experimental evidence, no additional FT details recorded" FT -35_signal 1092..1097 FT /citation=[5] FT /experiment="experimental evidence, no additional details FT recorded" FT -10_signal 1115..1120 FT /citation=[5] FT /experiment="experimental evidence, no additional details FT recorded" FT stem_loop 1144..1169 FT /note="II; site for premature transcription termination" FT /citation=[5] FT /experiment="experimental evidence, no additional details FT recorded" FT stem_loop 1172..1232 FT /note="III; site for RfaH-mediate regulation" FT /citation=[5] FT /experiment="experimental evidence, no additional details FT recorded" FT misc_feature 1185..1224 FT /note="JUMPstart" FT /citation=[5] FT /experiment="experimental evidence, no additional details FT recorded" FT misc_feature 1212..1219 FT /note="ops1" FT /citation=[5] FT /experiment="experimental evidence, no additional details FT recorded" FT gene 1298..2383 FT /gene="rmlB" FT /citation=[2] FT /experiment="experimental evidence, no additional details FT recorded" FT CDS 1298..2383 FT /codon_start=1 FT /transl_table=11 FT /gene="rmlB" FT /product="RmlB" FT /function="dTDP-rhamnose biosynthesis" FT /note="dTDP-glucose 4,6 dehydratase; formerly designated FT RfbB" FT /db_xref="GOA:P55293" FT /db_xref="HSSP:1KEW" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/Swiss-Prot:P55293" FT /citation=[2] FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="AAC63612.1" FT /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLAE FT ISDSERYSFENADICDAEGDGLYFGQHQLDAVMHLAAESHVDRSITGPAAFIETNIVGT FT YVLLEAARNYWSGLDDEKKKNFRFHHISTDEVYGDLPHPDEVNSNETLQLFTETTAYAP FT SSPYSASKASSDHLVRAWKRTYGLPTIVSNCSNNYGPYHFPEKLIPLVILNALEGKALP FT IYGKGDQIRDWLYVEDHARALYTVVTEGKAGETYNIGGHNEKKNIDVVFTICDLLDEIV FT PKEKSYREQITYVADRPGHDRRYAIDADKISRELGWKPQETFESGIRKTVEWYLANTNW FT VENVKSGAYQSWIEQNYEGRQ" FT gene 2383..3288 FT /gene="rmlD" FT /citation=[2] FT /experiment="experimental evidence, no additional details FT recorded" FT CDS 2383..3288 FT /codon_start=1 FT /transl_table=11 FT /gene="rmlD" FT /product="RmlD" FT /function="dTDP-rhamnose biosynthesis" FT /note="dTDP-4-keto-L-rhamnose 3,5 epimerase; formerly FT designated RfbD" FT /db_xref="GOA:Q46769" FT /db_xref="HSSP:1N2S" FT /db_xref="InterPro:IPR005913" FT /db_xref="UniProtKB/Swiss-Prot:Q46769" FT /citation=[2] FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="AAC63613.1" FT /translation="MNILLFGKTGQVGWELQRALAPLGNLIALDVHSTDYCGDFSNPEG FT VAETVKKIRPDVIVNAAAHTDVDKAESEPEFAQLLNATSVEAIAKAANEVGAWVIHYST FT DYVFPGTGEIPWQGGTDATAPLNVYGETKLSSEKKALQKHCGKHIIFRTSWVYAGKGNN FT FAKTMLRLAKEREELAVINDQFGRPTGAELLADCTAHAIRVAVDKPEVAGLYHLVAGGT FT TTWHDYAALVFEEARKAGINLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFALVL FT PDWQVGVKRMLNELFTTTAI" FT gene 3347..4228 FT /gene="rmlA" FT /citation=[2] FT /experiment="experimental evidence, no additional details FT recorded" FT CDS 3347..4228 FT /codon_start=1 FT /transl_table=11 FT /gene="rmlA" FT /product="RmlA" FT /function="dTDP-rhamnose synthesis" FT /note="glucose-1-phosphate thymidylyltransferase; formerly FT designated RfbA" FT /db_xref="GOA:P55253" FT /db_xref="HSSP:1H5R" FT /db_xref="InterPro:IPR005835" FT /db_xref="UniProtKB/Swiss-Prot:P55253" FT /citation=[2] FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="AAC63614.1" FT /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLM FT LAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEDFIGGDD FT CALVLGDNIFYGHDLPKLMEAAVNKESGATVFAYHVNDPERYGVVEFDNNGTAISLEEK FT PLEPKSNYAVTGLYFYDNDVVEMARKNLKPSARGELEITDINRIYMEQGRLSVAMMGRG FT YAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDAEQVKVLAEPLKKNA FT YGQYLLKMIKGY" FT gene 4233..4784 FT /gene="rmlC" FT /citation=[2] FT /experiment="experimental evidence, no additional details FT recorded" FT CDS 4233..4784 FT /codon_start=1 FT /transl_table=11 FT /gene="rmlC" FT /product="RmlC" FT /function="dTDP-rhamnose synthesis" FT /note="dTDP-6-deoxy-L-lyxo-4-hexulose reductase; formerly FT designated RfbC" FT /db_xref="GOA:Q46770" FT /db_xref="HSSP:1DZR" FT /db_xref="InterPro:IPR014710" FT /db_xref="UniProtKB/TrEMBL:Q46770" FT /citation=[2] FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="AAC63615.1" FT /translation="MNVIKTEIPDVLIFEPKVFGDERGFFMESFNQKVFEEAVGRKVEF FT VQDNHSKSTKGVIRGLHFQLPPYSQAKLVRCVVGEVYDVVVDIRKDSKTFGKWVRLVNL FT SAENKRQLWIPEGFGSHGFEVISEVASFLYKTNNYYNATMEKGIRWDDEYLAINWKEKK FT AIISEKDMKQPSFRELFEKV" FT gene 4788..6218 FT /gene="wzx" FT /note="synonym: rfbX" FT /citation=[6] FT /experiment="experimental evidence, no additional details FT recorded" FT CDS 4788..6218 FT /codon_start=1 FT /transl_table=11 FT /gene="wzx" FT /product="Wzx" FT /function="O-antigen translocase" FT /note="membrane protein" FT /db_xref="GOA:Q9XCW5" FT /db_xref="InterPro:IPR002797" FT /db_xref="UniProtKB/TrEMBL:Q9XCW5" FT /citation=[6] FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="AAD44153.1" FT /translation="MNNKLARQGLLWSTIERLGTQAIQLLLMLYLGRVLGPSSFGYVGM FT LTLFLSLAQVLIDSGFSAALIRKSERTEKDYSTVFIFNICLSILIYIVLYCLSSYIALF FT YQNTSAGIFYLIFSINRYSKWSNFNPQDSTHVDVNFKIQAKSSLIAITSSSVIAITLAA FT LGYGVWTLVFQSLSYSVINCIVLNIYNPWYPKEKFCYETFKKLFSFSSNLLIAGVLEAF FT YSNIYQLIIGKFFTPQLVGQFTQANQISSVPAMTLTNIIQRVTYPLFCNIYNGKGKIDD FT AYLNTLKIAGVVVFPILLGIGLISKPLVSVLLGSEWKFTSDILFLLCIAFMIYPIHAIN FT INILQVHGRSDLFLRLEILKKTLMTIILVITMQININAMVIGLVLHSYLSWFLNGLFSQ FT KVSTITIRKQLKELLPIWCLCLISGLGSNYIINEISMEPLLNIIFTILLNAIIYITLIR FT IMYKEIFMTIISLIKNKD" FT gene 6221..7336 FT /gene="vioA" FT /citation=[6] FT /inference="non-experimental evidence, no additional FT details recorded" FT CDS 6221..7336 FT /codon_start=1 FT /transl_table=11 FT /gene="vioA" FT /product="VioA" FT /function="synthesis of dTDP-4-amino-4,6-dideoxyglucose FT (dTDP-viosamine)" FT /note="nucleotide sugar transaminase" FT /db_xref="GOA:Q9XCW4" FT /db_xref="HSSP:1MDZ" FT /db_xref="InterPro:IPR015422" FT /db_xref="UniProtKB/TrEMBL:Q9XCW4" FT /citation=[6] FT /inference="non-experimental evidence, no additional FT details recorded" FT /protein_id="AAD44154.1" FT /translation="MNDKTIPVTQPSLPELAEFMPYLEKIWKNKWLTNNGPFHQELEEK FT LCEFLGVQHISLFNNATIALITALQALRITGEVITTPYSFVATSHAILWNGLTPVFVDI FT ENDGYNIDYRKIEQAITPKTSAILPVHCYSTPCEVEEIQKIADNYGLKVIYDAAHAFGV FT NFKGGKVYLTMVIYQFLVSMRRKSSINFEGGAIISPDAKTKLRIDRLKNFGIADELTVT FT APGINGKMSEINAAFGLVQLKHIEGSISKRKIIDSLYRNLLKGTPGITIFPGNINTNSN FT YSYFPILIDDGFHMSRDQAYELLKKNNILSRKYFYPLISNMPMYRGLISASVDNLPIAN FT SVADKVLCLPIYTDLNEEIVVKITKLLLGKM" FT gene 7338..7916 FT /gene="vioB" FT /citation=[6] FT CDS 7338..7916 FT /codon_start=1 FT /transl_table=11 FT /gene="vioB" FT /product="VioB" FT /function="synthesis of dTDP-4-acetamido-4,6-dideoxyglucose FT (dTDP-N-acetylviosamine)" FT /note="N-acetyltransferase" FT /db_xref="GOA:Q9XCW3" FT /db_xref="InterPro:IPR001451" FT /db_xref="UniProtKB/TrEMBL:Q9XCW3" FT /citation=[6] FT /protein_id="AAD44155.1" FT /translation="MAYLDEIQLKEMGFKSVGENVKISDKASFYGCDNISIGNNVRIDD FT FCVFSAGEGGIDIHDYIHIAVYSSIIGKGKVTISDYANISSRVSIYSSNEYYSGNYMSN FT PVVPSEYTNIHSGTVFIGKHVIIGCGSIVLPDVILHEGAAIGALSVVKEDCEAFTVNVG FT IPAKPISERSKKLLELESVFKPSAIGDNL" FT gene 7913..8659 FT /gene="wbbA" FT /citation=[6] FT CDS 7913..8659 FT /codon_start=1 FT /transl_table=11 FT /gene="wbbA" FT /product="WbbA" FT /function="putative rhamnosyltransferase" FT /db_xref="UniProtKB/TrEMBL:Q9XCW2" FT /citation=[6] FT /protein_id="AAD44156.1" FT /translation="MKIHIYFRHTDISRTTKNNRPEWFSHENCFINLINTIKESKYKDQ FT IAFTFIFDGSLNVASLDPLYQHFENIDMNNKKIFIINGGDQRKAWRECVKLVDEDRRVG FT KIDKNDLIYFLENDYLHESKWIDEIFNLVKSNIRWDMATLYDHPDKYSEYCEHLDSLKN FT KNKKTIVFYSGSRHWKIAPSTCATYIMKARVFDRTKIILKLAIYDYKLFLILTKIFRIR FT LLSPIPALSTHCMASLLSPSINWDDL" FT gene 8659..9321 FT /gene="wbbB" FT /citation=[6] FT CDS 8659..9321 FT /codon_start=1 FT /transl_table=11 FT /gene="wbbB" FT /product="WbbB" FT /function="putative N-acetylviosaminyl transferase" FT /db_xref="UniProtKB/TrEMBL:Q9XCW1" FT /citation=[6] FT /protein_id="AAD44157.1" FT /translation="MDCKKKLCHCGLSILKPEFIINKLYNYLPDYELDGVVISNNHIVE FT QITMKGFHIENGTNSLFEFSAYKEGIDFLEDSSLLPSGVPILILNDTLFLKHNAKFFLR FT KIVSYYSTIQRTELPTMAGRLDPYNNICYSNSWNNMNGYISSFCMLINEKSAKIIVSCY FT NELPKYFFSNDIDIIDPKWGMQIESRLREFIRSHLIDIDTDTVWYQAKLLHNDKQRI" FT gene 9478..10629 FT /gene="wzy" FT /citation=[6] FT /experiment="experimental evidence, no additional details FT recorded" FT CDS 9478..10629 FT /codon_start=1 FT /transl_table=11 FT /gene="wzy" FT /product="Wzy" FT /function="O-antigen polymerase" FT /note="formerly designated Rfc" FT /db_xref="UniProtKB/TrEMBL:Q9XCW0" FT /citation=[6] FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="AAD44158.1" FT /translation="MRKNFYTTPITLLILTLNIAATIVVINNSELLIGDLMGFKSETVV FT IIQSLIYISLSLLFLSVLYNGLEKIKPLTTKLADSNSRPIAIFLICLELLYITYVFNTG FT LFVAGNNERGGGVISALFVLLNVDVLVLIFLTHVKTSKYKPIIIMLWIISFLQRGWISY FT FFILILISFIDRRLKNKKNWKAGVVLICFILALPFVEQIKNSIRSGERISTQLTFFDYA FT DSFNQQFMKVVGRVQTVSHVAFITDNINQLQNLKNNGESTDFFEENFIYIIAKKLGSAD FT DKINTPDLLARYISPSLDSSWNVNPSLIGWIFIQNDLYVLPIIWVVLLCFLFTMLSKII FT ANDLYAMNMRWLFWLVFLFPGWIFQFTAVIFSAFSIYFIKVHT" FT gene 10700..11746 FT /gene="wbbC" FT /citation=[6] FT CDS 10700..11746 FT /codon_start=1 FT /transl_table=11 FT /gene="wbbC" FT /product="WbbC" FT /function="mannosyltransferase" FT /db_xref="GOA:Q9XCV9" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q9XCV9" FT /citation=[6] FT /protein_id="AAD44159.1" FT /translation="MGFGVYFRDLIAKNINEIFDGIDCEIIVVHQANIPVKELFNFPEN FT NNITYNPVKGINGKFSRVIYEQIFMPIKFRNYNIIYSPNNINPILFGGLTKCKSIITIH FT DLLPFRKANRFGLLQRLYLKFFTYMCAHKSEKIATVSNNSKNDIINTLNVKSDKVIVTY FT NILGDFKKSSIHQYDCETFFFSVGALHEDKQYDLMIKAFLKFKKLVNDNCKLLIAGGDH FT GAKKILQDLIDELKLNDHVQLLGYITDEDKWDYYENCCALILLGKYEGFGIPVLEAMSV FT NKPSIVANTGALPEIIGKAGFVINADIDSICDAMLKSYSYKVDPKLFEDELSRFSTNKQ FT INTLPAHV" FT gene 11761..12588 FT /gene="wbbD" FT /note="synonym: orf275" FT /citation=[1] FT /citation=[6] FT CDS 11761..12588 FT /codon_start=1 FT /transl_table=11 FT /gene="wbbD" FT /product="WbbD" FT /function="putative galactosyltransferase" FT /note="formerly designated ORF275" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q03084" FT /citation=[6] FT /citation=[1] FT /protein_id="AAC27537.1" FT /translation="MSDDTPKFSVLMAIYIKDSPLFLSEALQSIYKNTVAPDEVIIIRD FT GKVTSELNSVIDSWRRYLNIKDFTLEKNMGLGAALNFGLNQCMHDLVIRADSDDINRTN FT RFECILDFMTKNGDVHILSSWVEEFEFNPGDKGIIKKVPSRNSILKYSKNRSPFNHPAV FT AFKKCEIMRVGGYGNEYLYEDYALWLKSLANGCNGDNIQQVLVDMRFSKETAKRRGGIK FT YAISEIKAQYHFYRANYISYQDFIINIITRIFVRLLPTSFRGYIYKKVIRRFL" FT gene 12585..14009 FT /gene="manC" FT /note="synonym: formerly designated rfbM" FT /citation=[1] FT /experiment="experimental evidence, no additional details FT recorded" FT CDS 12585..14009 FT /codon_start=1 FT /transl_table=11 FT /gene="manC" FT /product="ManC" FT /function="GDP-mannose pyrophosphorylase" FT /EC_number="2.7.7.13" FT /note="formerly designated RfbM" FT /db_xref="GOA:P37741" FT /db_xref="InterPro:IPR001538" FT /db_xref="UniProtKB/Swiss-Prot:P37741" FT /citation=[1] FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="AAC27538.1" FT /translation="MSSPLIPVILSGGNGTRLWPLSREEYPKQFLKLTDSISMLQSTIS FT RLDSLNTSSPVVICNELHRFIVAEQLRHLNKLDNNIILEPSGRNTAPAICIAALILKMK FT HPNENPLMLVLPADHSVKKVKTFCNTIKSAIPFAEAGNLVSFGIKPTHPETGYGYIQKG FT KVLSDSDIYEVSEVRTFVEKPNLKTAESFIEKDEYYWNSGMYLFSVERYLQELSLYRPD FT IVKVCQETVKNIHYDMDFIRLDDKIFRNCPQESIDYAVMEKTKDAVVATMDIGWNDVGA FT WSSLWELGKKDSSGNVITGDIVCHETENSYIYTESGLVATIGIQDLVIIHTKDSLLVSR FT RDSVQNVKNIVQHLDLSGRKEHKEHREVFKSWGRCDSIDSSEKYHYQVKRITVNPSEKL FT SLQLHHHRAEHWVVVMGIAKLTVAEEIKILKENESVYIPAGIKHSLENIGTIPLVLIEV FT WTGSYLADDDILRFED" FT gene 14043..15404 FT /gene="manB" FT /citation=[1] FT /experiment="experimental evidence, no additional details FT recorded" FT CDS 14043..15404 FT /codon_start=1 FT /transl_table=11 FT /gene="manB" FT /product="ManB" FT /function="converts mannose-6-phosphate into FT mannose-1-phosphate" FT /EC_number="5.4.2.8" FT /note="phosphomannomutase; formerly designated RfbK" FT /db_xref="GOA:P37742" FT /db_xref="HSSP:1K2Y" FT /db_xref="InterPro:IPR005841" FT /db_xref="UniProtKB/Swiss-Prot:P37742" FT /citation=[1] FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="AAC27539.1" FT /translation="MLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLGGDV FT RLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPMDYNG FT MKLVREGARPISGDTGLRDVQRLAEANDFPPVDETKRGRYQQINLRDAYVDHLFGYINV FT KNLTPLKLVINSGNGAAGPVVDAIEARFKALGAPVELIKVHNTPDGNFPNGIPNPLLPE FT CRDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLEKNPGAKI FT IHDPRLSWNTVDVVTAAGTPVMSKTGHAFIKERMRKEDAIYGGEMSAHHYFRDFAYCDT FT GMIPWLLVAELVCLKGKTLGELVRDRMAAFPASGEINSKLAHPVEAINRVEQHFSREAL FT AVDRTDGISMTFADWRFNLRLLNTEPVVRLNVESRGDVPLMEEKTKLILELLNK" FT gene 15568..>15943 FT /gene="gnd" FT /citation=[1] FT /experiment="experimental evidence, no additional details FT recorded" FT CDS 15568..>15943 FT /codon_start=1 FT /transl_table=11 FT /gene="gnd" FT /product="Gnd" FT /function="gluconate-6-phosphate dehydrogenase" FT /EC_number="1.1.1.44" FT /db_xref="GOA:P00350" FT /db_xref="HSSP:2PGD" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/Swiss-Prot:P00350" FT /citation=[1] FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="AAC27540.1" FT /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKQEEVIAE FT NPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGNTF FT FQDTIRRNRELSAEGFNFYRY" XX SQ Sequence 15943 BP; 5024 A; 2690 C; 3325 G; 4904 T; 0 other; attttacagg tggatgaaat aatgacgaat ttaaaagcag ttattcctgt agcgggtctt 60 gggatgcata tgttgcctgc cactaaggcg attcccaaag agatgctacc gattcccgtc 120 gacaagccaa tgattcagta catcgttgac gagattgtgg ctgcagggat caaagaaatc 180 ctcctggtaa ctcacgcttc caagaacgcg gtcgaaaacc acttcgacac ctcttatgaa 240 ttagaatctc tccttgaaca gcgcgtgaag cgtcaactgc tggcggaagt acagtccatt 300 tgcccgccgg gcgtgacaat tatgaacgtg cgtcagggcg aacctttagg tttgggccac 360 tccattttat gtgcacgacc tgccattggt gacaatccat ttgtcgtggt gctgccagac 420 gttgtgatcg acgacgccag cgccgacccg ctgcgctaca accttgctgc catgattgcg 480 cgcttcaacg aaacgggccg cagccaggtg ctggcaaaac gtatgccggg tgacctctct 540 gaatactctg tcatccagac caaagagccg ctggaccgcg aaggtaaagt cagccgcatt 600 gttgaattca tcgaaaaacc ggatcagccg cagacgctgg actcagacat catggccgtt 660 ggtcgctatg tgctttctgc agatatttgg ccggaacttg aacgcactca gcctggtgca 720 tgggggcgta ttcagctgac tgatgccatc gctgaactgg cgaaaaaaca gtccgttgat 780 gccatgctga tgacaggtga cagctacgac tgcggtaaaa aaatggggta tatgcaggca 840 tttgtgaagt atggactacg caacctgaaa gaaggggcga agttcctgaa agggattgag 900 aagctgttaa gcgaagtaac aaattcctga ctggaagtgt cggtcagtaa gtagagttaa 960 aaacggcaag gtgaaggatt caatagcata agttttgctc attgaatctc actgccgttg 1020 tcttttttat aagtacaata aaaacagcat gttagcttgc aatcatagtt caattttttc 1080 caggattttc cttgtttcta cagctgtttg gtaagacaat tagcgtttga atttttcgga 1140 tttggcacga gtgggttacg ctcgtcacat cgtggaaatg tacgcagtgc tctggtagct 1200 gttaagccag gggcggtagc gtgcattaat gcatctatta atcaaatctg gagcagtcta 1260 tttcacagca tgctctctgg ctatatggaa taaaaaagtg aagatacttg ttactggtgg 1320 cgcaggattt attggttctg ctgttgttcg tcacataata aataatacgc aagatagtgt 1380 tgttaatgtc gataaattaa catacgccgg aaacctggaa tcactcgctg aaatttctga 1440 ttctgaacgt tattcatttg agaatgcaga tatctgcgat gccgaaggcg atggcttgta 1500 ttttggacag caccagctag acgcggtgat gcacctggca gcagagagcc acgttgaccg 1560 ctcaataact gggcctgcgg catttattga aaccaatatt gtgggtactt atgttctttt 1620 agaagcggcg cgcaattatt ggtctggtct ggatgatgaa aagaaaaaaa acttccgttt 1680 tcatcatatt tctactgatg aggtgtatgg tgacttaccc catccggatg aagtaaatag 1740 caatgaaacg ttgcagctat ttacggaaac gacagcatac gcgccaagta gtccatattc 1800 tgcttctaaa gcttccagcg atcatttggt tcgcgcatgg aaacgtactt atggtttacc 1860 gaccattgtg tctaattgct cgaacaacta tggtccttat catttcccgg aaaagcttat 1920 tccactggtt attcttaatg cactggaagg taaggcatta cctatttatg gcaaaggaga 1980 tcagatccgc gactggttgt atgtagagga tcatgctcga gcgttatata ccgtcgtaac 2040 cgaaggtaaa gcgggcgaaa cttataacat tggtggacac aacgaaaaga aaaacatcga 2100 cgtagtgttc actatttgtg atttgttgga tgagatagtc ccgaaagaga aatcttatcg 2160 tgagcaaatt acctatgttg ctgatcgccc agggcatgat cgccgttatg caattgatgc 2220 cgataaaatt agccgcgaat tgggctggaa accgcaagaa acgtttgaga gcggtattcg 2280 taaaacggtg gaatggtatc tggctaatac aaattgggtt gagaatgtga aaagcggtgc 2340 ttatcagtcg tggattgaac agaactatga gggccgccag taatgaatat cctcctattc 2400 ggcaaaacag ggcaggtagg ttgggaactg cagcgtgctc tggcaccgct gggtaatctg 2460 attgctcttg atgttcactc cactgattat tgtggtgatt ttagtaatcc cgaaggtgta 2520 gctgaaactg tcaaaaaaat tcgccctgat gttattgtta atgcggctgc tcacactgac 2580 gtagacaaag cggaatcaga accggaattt gcacaattac ttaacgcgac aagtgtcgaa 2640 gcgattgcaa aagcagccaa tgaagtcggt gcttgggtta ttcactactc tactgactac 2700 gtatttccgg gaaccggtga aataccgtgg cagggaggaa cggatgctac agcacctttg 2760 aatgtttatg gtgaaactaa acttagctcc gagaaaaaag cgttacagaa acattgcggc 2820 aagcatatta ttttccgtac cagctgggta tatgcaggta aaggaaataa cttcgccaaa 2880 acaatgttgc gtctggcaaa agagcgcgaa gaactggctg tgataaacga tcagtttggc 2940 cgaccaacag gtgccgaatt gctggctgat tgcaccgctc atgccattcg cgtagcagta 3000 gacaaaccag aagttgctgg tttgtaccat ctggttgctg gcggtacaac aacctggcac 3060 gattatgccg ctctggtatt tgaagaagcg cgcaaagcag ggattaacct tgctcttaac 3120 aaacttaacg ccgtgccaac aacggcctat cccacaccag cccgtcgacc ccataactct 3180 cgcctcaata cagaaaagtt tcagcagaac tttgcgcttg tcttgcctga ctggcaggtg 3240 ggtgtgaaac gaatgctcaa cgaattattt acgactacgg caatttaaca aatttttgca 3300 tctcgctcat gatgccagag cgggatgaat taaaaggaat ggtgaaatga aaacgcgtaa 3360 aggtattatt ctggctggtg gttccggcac tcgtctttat cctgtgacga tggcagtaag 3420 taaacaactg ctgccgattt atgataagcc gatgatttat tatccgcttt caacgcttat 3480 gttagcgggt attcgcgata ttcttattat cagtacgcca caggatacgc cgcgtttcca 3540 acaattgttg ggggacggga gccagtgggg gcttaatcta cagtataaag tacaaccgag 3600 tccggatggc ctggcgcaag cgtttatcat tggtgaagac tttattggtg gcgatgattg 3660 tgcacttgtg cttggtgata atatcttcta tggacacgac ttgccgaaat taatggaagc 3720 tgctgttaac aaagaaagcg gtgcaacggt atttgcttat cacgttaatg atcctgaacg 3780 ttatggtgtc gtggagtttg ataataacgg tactgcaatt agcctggaag aaaaaccgct 3840 ggaaccaaaa agtaactatg cggttactgg gctttatttc tatgacaatg acgttgtgga 3900 aatggcccgg aaaaacctta agccttctgc ccgaggtgaa ctggaaatta ccgatattaa 3960 ccgtatttat atggaacaag gacgtttgtc tgtcgctatg atggggcgtg gctatgcatg 4020 gctggataca gggacgcatc aaagtcttat tgaagcaagc aacttcattg ccaccattga 4080 agagcgccag ggactaaagg tttcctgtcc ggaagaaatt gcttatcgta aagggtttat 4140 tgatgctgag caggtaaaag tattagccga accgttgaag aaaaatgctt atggtcagta 4200 tctgctcaaa atgattaaag gttattaata agatgaacgt aattaaaact gaaattcctg 4260 atgtattaat atttgaacca aaagtatttg gggatgagcg tggttttttt atggaaagct 4320 tcaatcagaa agttttcgaa gaagctgtgg ggcggaaggt tgaatttgtt caggataacc 4380 attctaagtc tactaaagga gtaattagag gattacattt tcaattacca ccttattcac 4440 aggcaaaatt agtacgctgt gtagtaggtg aggtatatga cgttgttgtt gatataagga 4500 aagattctaa aacttttggc aaatgggtcc ggcttgtaaa tctttctgct gaaaacaaac 4560 gacagttgtg gattccagaa ggattcggtt cccatggttt tgaagtgatt agtgaagttg 4620 cttctttttt atacaaaaca aataattatt ataatgcaac tatggaaaaa ggtataagat 4680 gggatgatga atatttagct attaattgga aagaaaaaaa agcgataatc tctgagaaag 4740 acatgaaaca accatcattc agagaacttt ttgagaaagt ttaattgatg aataacaaac 4800 tagccaggca aggattatta tggagcacaa ttgaaaggct aggaacgcaa gccatacaat 4860 tattattaat gttgtatttg ggtagggttc ttggaccaag ctcttttggt tatgttggta 4920 tgctaacttt atttctatca ttagctcagg ttctaattga tagtggattt agtgcagcat 4980 taattagaaa atcggagcgt actgaaaaag attattcgac agtatttata tttaatattt 5040 gtctatcaat actaatatat attgtacttt attgtttatc ttcttatatt gctttattct 5100 atcaaaatac ctctgctgga atcttttact tgatatttag cattaacaga tatagcaaat 5160 ggtctaactt taatccccaa gattcaactc acgtagacgt gaattttaag atccaagcta 5220 aaagttcact tatcgctatt accagtagta gtgtaatagc gataacgtta gctgctttgg 5280 gttatggagt atggacattg gttttccaat cgttatccta tagtgtcata aattgtattg 5340 tactgaatat ttataatcca tggtatccaa aagagaaatt ttgctatgaa acattcaaaa 5400 agctattttc atttagcagt aacttactaa ttgctggagt acttgaagct ttttattcaa 5460 atatatatca attaattata gggaaatttt ttacaccaca gcttgtaggg caatttacac 5520 aggctaatca gatctctagc gtacctgcaa tgacacttac taatattatt cagagagtaa 5580 cttatccact tttttgtaat atttataatg gcaaagggaa aatagatgat gcttatttaa 5640 acacacttaa aattgcaggc gttgtagttt ttccaattct attaggaata ggtttaatct 5700 cgaagccatt agtctctgta ttattaggaa gtgagtggaa atttacatct gatattctgt 5760 ttctactttg tattgcattt atgatttatc ctatacatgc aataaatatt aatatcctac 5820 aggttcatgg gcgaagtgat ctttttttgc gtttggaaat actaaaaaag acattgatga 5880 caattattct tgtcattacg atgcaaataa atataaatgc aatggtgatt ggtttagttt 5940 tacactcata tctttcgtgg tttttaaatg gattatttag ccagaaagta tcaacgatca 6000 caataaggaa gcagttaaaa gagttactac ctatatggtg tctatgttta attagtgggt 6060 taggttctaa ctatattata aatgaaataa gtatggaacc tttattaaat ataatattta 6120 ctattttatt aaatgccatt atatacatca cactaattcg aattatgtac aaagaaatat 6180 ttatgactat tatttctctt ataaaaaata aggactgaaa atgaacgata aaactattcc 6240 agtaacgcaa ccttctttgc cggaacttgc agaattcatg ccttacctgg aaaaaatatg 6300 gaaaaataaa tggttgacaa ataatggacc atttcatcaa gaactcgagg aaaaattatg 6360 tgaatttttg ggtgtgcagc atatctcgct ttttaacaat gcaacaattg cattgatcac 6420 agcattacaa gccctaagaa taacaggtga ggtaataaca acaccatatt catttgttgc 6480 aacttcacat gctattttat ggaatggact tacgcctgtc tttgttgata ttgaaaatga 6540 tggatataat attgattaca gaaaaataga acaggctatt acaccaaaaa cttcagcaat 6600 tttacctgtc cattgctact caacaccctg tgaagtcgaa gaaattcaaa aaatagctga 6660 taattatgga ttgaaagtaa tctacgacgc agcacatgca ttcggtgtaa attttaaagg 6720 gggcaaagtt tacttaacta tggtgattta tcaattctta gtttccatgc gacgaaagtc 6780 ttcaataaac tttgaaggtg gggcaataat tagccctgat gctaaaacca agttacgtat 6840 agatcgatta aaaaactttg gtatcgccga cgagctgact gtgacagctc caggaataaa 6900 tggcaaaatg agtgaaatta atgctgcctt tggacttgtt cagttaaagc atattgaggg 6960 ctcaatatct aagcgaaaaa taattgatag tctttaccgg aatttactga aagggactcc 7020 gggtattact atatttccag gaaatataaa tacaaatagc aactattcat attttcctat 7080 actcatagat gatggttttc atatgagtcg tgatcaggca tatgaattac ttaagaaaaa 7140 taatatccta tctcgaaagt atttttatcc attaatcagt aatatgccta tgtatcgagg 7200 attgatttca gctagcgttg ataatctacc aatagccaat agtgttgctg ataaagtcct 7260 atgcttgcca atatatacag atttaaatga agagattgtt gtgaaaataa ccaaattatt 7320 attgggtaag atgtgatatg gcctatttag atgaaataca gttaaaagaa atgggcttca 7380 aaagcgttgg agaaaatgta aaaatatcag ataaggcatc tttttatggg tgtgataata 7440 ttagtattgg gaataatgta aggattgatg atttttgcgt gttttcagct ggagagggtg 7500 gtattgatat acacgattat attcatatag cggtatattc ttcaattatt ggcaaaggaa 7560 aagtaactat atctgactac gcaaacattt catctcgagt ctcaatatat tccagtaacg 7620 agtattattc tggcaattat atgtctaatc cagtagttcc aagtgaatat acgaatatac 7680 atagcggtac tgtatttata ggcaaacatg ttatcatagg ttgcggaagt attgttcttc 7740 cggatgttat tttacatgag ggtgcagcaa ttggagctct ttctgtagtc aaagaggatt 7800 gtgaagcttt tacggtaaat gtaggtatac cagctaaacc aatatctgaa agaagcaaga 7860 aattattgga gcttgaatct gtatttaaac caagcgctat tggagataat ctgtgaagat 7920 tcatatttat tttcggcata cggatattag tcggacaact aaaaataatc ggcctgagtg 7980 gtttagtcat gaaaattgtt ttataaatct tataaataca ataaaagaat ctaaatataa 8040 agaccaaata gcatttactt ttatttttga tggatcatta aacgttgctt ccttagatcc 8100 gttatatcaa cactttgaaa atatcgatat gaataataaa aagatattca taatcaatgg 8160 aggagatcag cgcaaagcat ggcgtgaatg cgtaaaacta gtagatgaag atcgtcgagt 8220 tggaaaaatt gataaaaatg atttaatata ttttttagaa aatgattatt tgcatgagtc 8280 taaatggatt gatgagatat ttaacttggt caaatcaaat ataagatggg atatggcaac 8340 gctttatgat catccagata aatatagtga atattgtgaa catcttgatt cattaaaaaa 8400 taaaaacaaa aaaactattg tattttattc tgggagtagg cattggaaaa tagcaccaag 8460 tacatgtgca acatatatta tgaaagccag ggtttttgat aggacaaaaa taattctaaa 8520 attagctatt tacgattaca aattattttt gatacttact aaaatattta gaattagact 8580 tctttcacct atccccgctc tttcaactca ttgtatggct tctttgttat caccttcaat 8640 caattgggat gatttataat ggattgtaaa aaaaaattat gccattgtgg cctgtctata 8700 cttaagccag aattcataat taataaatta tataattatt taccagatta tgaactagat 8760 ggtgttgtga tttccaataa tcatatagta gaacagatta caatgaaggg atttcatatc 8820 gaaaacggga caaattctct ttttgagttt tctgcctata aggaaggaat agatttttta 8880 gaagatagct cattattacc atcaggagta ccaattctca ttttgaatga tacattgttc 8940 ttgaaacata atgcaaaatt ctttttaagg aaaattgtga gttattattc aacaattcaa 9000 agaactgaat tgcctacaat ggcaggtcgt ttagatcctt ataataatat atgttacagt 9060 aactcttgga ataatatgaa tggctatata tcttcctttt gtatgctaat aaatgaaaaa 9120 tctgcaaaaa taattgttag ttgctacaat gagcttccaa aatatttttt tagtaatgat 9180 attgatatta ttgaccccaa atggggaatg cagattgaat caagactgag agaatttatt 9240 cgtagtcatt taattgatat agacacagat acggtttggt atcaagctaa attgttacat 9300 aatgataaac aacgaattta atatttaaag ctcaatgtgt cttcatggaa catttcatat 9360 cagggaagat tggtgaaagt ggaattgttg tttctatttt ttcccacatg gaaaggaaag 9420 ggtgttaaat tttttaaacg agcaattggc taaaatcaag aggaagatta taattaaatg 9480 agaaaaaatt tttacacgac accaatcaca ttactaattc ttacgcttaa tattgctgca 9540 acaattgtag ttataaacaa cagtgaatta ttgattggcg atttaatggg gtttaaatca 9600 gaaactgtcg taataattca atctctaatt tatatatctc ttagcttatt atttctatcg 9660 gtattatata atggattgga aaaaataaaa ccacttacaa caaaattagc tgattctaat 9720 agtagaccga tcgccatttt tttaatttgt ttagaattat tatatataac atacgtattt 9780 aatacaggct tatttgttgc tggtaataat gagcgcggag gcggagtaat ttcagcgtta 9840 tttgtattac tgaatgttga tgtacttgtt ttaatatttc taacacatgt taaaacaagt 9900 aagtacaagc ccattattat catgttgtgg attatttctt ttcttcagcg tggttggata 9960 tcttattttt tcattttgat tttaatctca tttatcgatc gtcgattgaa aaacaaaaaa 10020 aattggaaag ctggggtagt attaatatgt tttattctgg ctctgccatt tgtagaacag 10080 attaagaatt ctatcagaag tggcgaacgt atcagcacgc aattaacttt ttttgattat 10140 gcggattctt ttaatcaaca atttatgaag gttgttggca gagttcaaac agtttcacac 10200 gttgcattta taacagataa tattaatcaa cttcagaatt taaaaaataa tggagaatct 10260 actgattttt ttgaagaaaa ttttatttat ataattgcta aaaaattagg gagtgctgat 10320 gataagatta atactccaga tttgcttgcc agatatattt ctccatctct ggatagctca 10380 tggaatgtga atccatcgtt aattggttgg atttttattc aaaatgattt atacgttcta 10440 cccatcatat gggttgtttt gctgtgtttt ctatttacaa tgctatctaa aattattgcg 10500 aatgacctat atgcaatgaa tatgagatgg ttgttttggt tagtgttttt atttccgggt 10560 tggatattcc aattcacagc agttatattt tcggctttta gtatttattt tattaaagta 10620 cacacttagg actaaaagag taaaccttta tgacgaaaat agttttcaat ttactatctt 10680 tttgcagaat taaaatatta tggggtttgg agtatacttt agagatttaa ttgcaaaaaa 10740 tattaatgaa atattcgatg ggattgattg cgaaataata gttgttcacc aggctaatat 10800 ccctgttaaa gaattgttca attttccaga aaacaataat attacctata atcctgtaaa 10860 aggcattaat gggaaatttt cgcgtgttat ttacgaacag atatttatgc cgattaaatt 10920 tcgtaactat aacataattt attccccaaa taatattaat ccgattcttt ttgggggtct 10980 aactaaatgt aagtcaataa ttactattca tgacttgctt ccatttagaa aggctaatag 11040 atttggtctt ctacaaagat tgtatctaaa gtttttcaca tatatgtgtg ctcacaaatc 11100 ggaaaaaatc gctacagtgt ccaataattc aaaaaatgat attatcaata cccttaatgt 11160 caagagcgat aaggttattg taacttacaa tatattaggt gattttaaaa aatcctctat 11220 acaccaatat gattgtgaaa cctttttttt ctcggtgggt gctttgcatg aagataaaca 11280 atacgatttg atgataaagg cttttctaaa gttcaaaaaa ttagtcaatg ataattgtaa 11340 attattaatt gctgggggtg atcatggagc taagaaaatt ttacaggact tgattgatga 11400 attaaaatta aatgaccatg ttcaattatt aggatatatc actgatgaag ataagtggga 11460 ctactatgaa aattgttgtg cacttatctt actagggaaa tatgaaggtt ttggtattcc 11520 tgtattggaa gctatgagtg tcaataagcc atcaattgta gcaaataccg gggctctacc 11580 tgagatcata ggtaaagcag gatttgtcat aaatgctgat attgattcaa tttgtgatgc 11640 tatgttaaaa agctattcat ataaagttga cccaaaattg tttgaagatg aattatcacg 11700 cttttctact aataaacaaa taaatacttt gccagcacat gtttaaggaa atatgtaaag 11760 atgtcagatg acactccaaa gttttctgtt ttgatggcta tatacatcaa ggattctccc 11820 ctatttctct ctgaggcttt acaatcaatt tataaaaata cggttgcccc agatgaagtt 11880 attattattc gtgatggtaa ggtcacatct gaactcaatt ctgttattga tagttggaga 11940 agatatttaa atataaaaga tttcacactt gaaaaaaata tggggttggg ggcagcgtta 12000 aattttgggt tgaatcaatg tatgcatgat ttagtaatac gtgctgattc tgatgatata 12060 aatagaacaa atcgattcga atgtatactt gattttatga ctaagaatgg tgatgttcat 12120 attcttagct cttgggttga agagttcgaa ttcaatccag gagataaggg cataataaaa 12180 aaagtaccaa gtcggaattc tatacttaaa tattcaaaaa acagatctcc ttttaatcac 12240 cctgcagttg catttaaaaa gtgtgaaata atgcgcgtcg gcggttatgg aaatgagtac 12300 ttatatgaag attatgccct ttggttgaaa tctttagcta atggatgtaa tggtgataat 12360 attcaacaag ttttagttga tatgagattt tcaaaggaaa cagcaaaaag acgaggtgga 12420 ataaaatatg ccatttcaga aattaaagct cagtatcatt tttatcgtgc aaattatata 12480 tcatatcaag actttataat aaatattatc acaaggatat ttgttagact tcttcccact 12540 agttttcgtg gctatatata taaaaaagtt atcaggagat ttttatgagc tcacctctta 12600 ttccggttat attaagtggt ggtaatggta ctaggttatg gccactatct agagaggaat 12660 atcctaagca gtttttaaaa ctaaccgact caatatcaat gctgcaatca acaatatctc 12720 ggttagactc attaaatact tcctctccag ttgtaatatg caatgaatta cacagattta 12780 ttgttgcaga acaactcagg cacttaaata aattagataa taatattatt ttagaaccat 12840 ctggtcgcaa tactgcacct gctatttgta ttgctgcttt aattttaaaa atgaagcatc 12900 caaatgaaaa tccacttatg ctcgttcttc cagccgatca ctccgtaaaa aaagtcaaaa 12960 ctttttgtaa tacaataaaa agtgctattc ccttcgctga agctggtaat ttggtttctt 13020 ttggtattaa acctactcat cctgagacgg ggtatggata tatacaaaaa ggcaaagtgt 13080 tatctgattc tgatatatat gaggtcagtg aagttagaac ttttgttgaa aagcctaatc 13140 ttaaaacagc agaaagcttt atagaaaaag atgagtatta ttggaatagt ggtatgtatt 13200 tgttcagtgt tgaacgttac ttacaagagt tatcattata ccgaccagac atagttaaag 13260 tatgccagga aactgttaaa aatattcatt atgatatgga ttttattaga ttggacgata 13320 aaatatttcg gaactgtcca caggagtcta ttgattatgc tgtaatggag aaaacaaagg 13380 atgctgtagt tgctacaatg gatatcggtt ggaatgatgt aggagcatgg tcttcgcttt 13440 gggaattagg gaaaaaagac tcctctggta atgttatcac gggagacatc gtttgccacg 13500 agacagaaaa tagttatatt tatactgagt ctggattggt agcaactatt ggtattcaag 13560 atcttgttat tattcatact aaagattcat tactggtttc cagacgcgat tcagtacaaa 13620 atgtaaaaaa tattgttcag catcttgatt tgtcaggacg taaagaacat aaagaacata 13680 gggaagtatt caagtcatgg ggacgatgtg actccataga tagtagcgaa aagtaccact 13740 atcaggtcaa acgaataaca gttaatccaa gtgaaaaatt atcgttgcaa ttacatcatc 13800 accgtgcgga acattgggtt gttgtaatgg ggattgctaa acttacagtt gcagaagaaa 13860 taaaaatttt aaaagagaat gagtctgtat atattcctgc aggtattaag catagtttgg 13920 aaaatattgg gacaatacca cttgtgttaa tagaagtttg gaccggttct tatcttgctg 13980 atgatgatat ccttcgattt gaagattgat atggtagagc ttagaaatag agagtcttaa 14040 taatgctaac ttgctttaaa gcttatgata ttcgcgggaa actaggcgaa gaactgaatg 14100 aagatatcgc ctggcgcatt gggcgtgcct atggcgaatt tctcaaaccg aaaaccattg 14160 tgttaggcgg tgatgtccgc ctcaccagcg aaaccttaaa actggcgctg gcgaaaggtt 14220 tacaggatgc gggcgtcgat gtgctggata tcggtatgtc cggcaccgaa gagatctatt 14280 tcgccacgtt ccatctcggc gtggatggtg gcattgaagt taccgccagc cataatccga 14340 tggattataa cggcatgaaa ctcgtgcgcg agggggctcg cccgatcagc ggggataccg 14400 gactgcgcga tgtccagcgt ctggcagaag ccaacgactt ccctcccgtt gatgaaacca 14460 aacgcggtcg ttatcagcaa atcaatctgc gtgacgctta cgttgatcac ctgttcggtt 14520 atatcaacgt caaaaacctc acgccgctca agctggtgat taactccggg aatggcgcgg 14580 cggggccggt ggtggacgcc attgaagccc gctttaaagc cctcggcgca ccggtggaat 14640 taatcaaagt acacaacacg ccggacggca atttccccaa cggtattcct aacccgttgc 14700 tgccggaatg ccgcgacgac acccgtaatg cggtcatcaa acacggcgcg gatatgggca 14760 ttgcctttga tggcgatttt gaccgctgtt tcctgtttga cgaaaaaggg cagtttatcg 14820 agggctacta cattgtcggc ctgctggcag aagcattcct cgaaaaaaat cccggcgcga 14880 agatcatcca cgatccgcgt ctctcctgga acaccgttga tgtggtgacc gccgcgggca 14940 ccccggtaat gtcgaaaacc ggacacgcct ttattaaaga acgtatgcgc aaggaagacg 15000 ccatctacgg tggcgaaatg agcgcccacc actatttccg tgatttcgct tactgcgaca 15060 cgggcatgat cccgtggctg ctggtggccg aactggtgtg tctgaaagga aaaacgctgg 15120 gcgaactggt gcgcgaccgg atggcggcgt ttccggcaag cggtgagatc aacagcaaac 15180 tggcgcaccc cgttgaggcg attaatcgcg tcgaacagca ttttagccgc gaggcgctgg 15240 cggtggatcg caccgatggc atcagcatga cctttgccga ctggcgcttt aacctgcggc 15300 tcctcaacac cgaaccggtg gtgcggttga atgtggaatc gcgcggtgat gtaccgctga 15360 tggaagaaaa gacaaaactt atccttgagt tactgaacaa gtaattcagt aatttcatat 15420 aaatggtttt taaaaaacgg aaaagatgag atatccggtg tggtatagcc aaggtaatgc 15480 tattcagtat ctctatgagt gagttaacat ctataccaca tttaagccgc acacttcgcg 15540 gtgaccaccc cctgacagga gtaaacaatg tcaaagcaac agatcggcgt cgtcggtatg 15600 gcagtgatgg ggcgcaacct cgcgctcaac atcgaaagtc gtggttatac cgtctctatt 15660 ttcaaccgtt cccgtgaaaa gcaggaagaa gtgattgccg aaaatccagg caagaaactg 15720 gttccttact atacggtgaa agagtttgtt gaatctctgg aaacgcctcg tcgcatcctg 15780 ttaatggtga aagcaggtgc aggcacggat gctgctattg attccctcaa gccatacctc 15840 gataaaggtg acatcatcat tgatggtggt aataccttct tccaggacac cattcgtcgt 15900 aaccgtgagc tttctgccga aggctttaat ttttatcggt acc 15943 // |
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