EBI Dbfetch

ID   AF105998; SV 1; linear; genomic DNA; STD; MUS; 427 BP.
XX
AC   AF105998;
XX
DT   23-MAR-1999 (Rel. 59, Created)
DT   14-NOV-2006 (Rel. 89, Last updated, Version 3)
XX
DE   Mus musculus methylenetetrahydrofolate reductase gene, exon 11 and complete
DE   cds.
XX
KW   .
XX
OS   Mus musculus (house mouse)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea;
OC   Muridae; Murinae; Mus.
XX
RN   [1]
RP   1-427
RX   DOI; 10.1007/s003359900838
RX   PUBMED; 9680386.
RA   Goyette P., Pai A., Milos R., Frosst P., Tran P., Chen Z., Chan M.,
RA   Rozen R.;
RT   "Gene structure of human and mouse methylenetetrahydrofolate reductase
RT   (MTHFR)";
RL   Mamm. Genome 9(8):652-656(1998).
XX
RN   [2]
RP   1-427
RA   Goyette P., Pai A., Milos R., Frosst P., Tran P., Chen Z., Chan M.,
RA   Rozen R.;
RT   ;
RL   Submitted (11-NOV-1998) to the EMBL/GenBank/DDBJ databases.
RL   Medical Genetics, Montreal Children's Hospital, Research Institute, 4060
RL   Ste-Catherine Street West, Rm. 242, Montreal, Quebec H3Z 2Z3, Canada
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..427
FT                   /organism="Mus musculus"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:10090"
FT   mRNA            join(AF105988.1:51..293,AF105989.1:51..289,
FT                   AF105990.1:51..161,AF105991.1:51..244,AF105992.1:51..301,
FT                   AF105993.1:51..185,AF105994.1:51..231,AF105995.1:51..233,
FT                   AF105996.1:51..152,AF105997.1:51..170,51..>266)
FT                   /product="methylenetetrahydrofolate reductase"
FT   CDS             join(AF105988.1:61..293,AF105989.1:51..289,
FT                   AF105990.1:51..161,AF105991.1:51..244,AF105992.1:51..301,
FT                   AF105993.1:51..185,AF105994.1:51..231,AF105995.1:51..233,
FT                   AF105996.1:51..152,AF105997.1:51..170,51..266)
FT                   /codon_start=1
FT                   /product="methylenetetrahydrofolate reductase"
FT                   /note="MTHFR"
FT                   /db_xref="GOA:Q9WU20"
FT                   /db_xref="InterPro:IPR003171"
FT                   /db_xref="InterPro:IPR004621"
FT                   /db_xref="MGI:106639"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q9WU20"
FT                   /protein_id="AAD20313.1"
FT                   /translation="MVNEARGSGSPNPRSEGSSSGSESSKDSSRCSTPSLDPERHERLR
FT                   EKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDK
FT                   ETSSMMIASTAVNYCGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPVGDH
FT                   WEAEEGGFSYATDLVKHIRTEFADYFDICVAGYPRGHPDAESFEDDLKHLKEKVSAGAD
FT                   FIITQLFFEASTFFSFVKACTEIGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQKIKD
FT                   VIEPIKDNDAAIRNYGIELAVRLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTE
FT                   DPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGEL
FT                   KDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWNDEP
FT                   LAAETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTS
FT                   RETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDP
FT                   ISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDSCLWQVV
FT                   EDTFELLNRHPTERETQAP"
FT   exon            51..266
FT                   /number=11
XX
SQ   Sequence 427 BP; 97 A; 131 C; 116 G; 83 T; 0 other;
     ggaggtacca gccgtgctga ccctgctcgt gtgtctctgt tcacacgtag gatgaggcct        60
     ttgccctgtg gatcgagcag tggggcaagc tatacgagga ggagtcgcca tcccgcatga       120
     tcatccaata catccatgac aactatttcc tggtcaacct ggtggacaac gagttcccgc       180
     tggacagctg cctgtggcag gtggtggagg acacgtttga gctgctcaac aggcatccca       240
     cggagagaga gacacaggct ccatgagcct gcatctctca acaggcacac catggagaga       300
     gagacacagg ctctgtgagc cgtgcatccc tcaacaggca caccacggag agagagacac       360
     aggctccgtg agcctgcatc ccggtatctt cctcacctgg agcccctctc cctcatctct       420
     ctacaca                                                                 427
//