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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   AF090119; SV 1; linear; mRNA; STD; MAM; 1218 BP.
XX
AC   AF090119;
XX
DT   02-AUG-1999 (Rel. 60, Created)
DT   14-NOV-2006 (Rel. 89, Last updated, Version 4)
XX
DE   Equus caballus caspase-1 mRNA, complete cds.
XX
KW   .
XX
OS   Equus caballus (horse)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
XX
RN   [1]
RP   1-1218
RX   PUBMED; 10376217.
RA   Wardlow S., Penha-Goncalves M.N., Argyle D.J., Onions D.E., Nicolson L.;
RT   "Nucleotide sequence of equine caspase-1 cDNA";
RL   DNA Seq. 10(2):133-137(1999).
XX
RN   [2]
RP   1-1218
RA   Wardlow S., Argyle D.J., Onions D.E., Nicolson L.;
RT   ;
RL   Submitted (03-SEP-1998) to the EMBL/GenBank/DDBJ databases.
RL   Vet Pathology, Glasgow Vet School, Bearsden Rd, Glasgow G61 1QH, Scotland,
RL   UK
XX
DR   Ensembl-Gn; ENSECAG00000024367; Equus_caballus.
DR   Ensembl-Tr; ENSECAT00000026255; Equus_caballus.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1218
FT                   /organism="Equus caballus"
FT                   /mol_type="mRNA"
FT                   /db_xref="taxon:9796"
FT   CDS             1..1218
FT                   /codon_start=1
FT                   /product="caspase-1"
FT                   /note="cysteinyl aspartate-specific protease;
FT                   interleukin-1beta-converting enzyme; ICE"
FT                   /db_xref="GOA:Q9TV13"
FT                   /db_xref="HSSP:1ICE"
FT                   /db_xref="InterPro:IPR015917"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q9TV13"
FT                   /protein_id="AAD46400.1"
FT                   /translation="MADKVLKEKRRLFIRSVGTGTVNSLLDELLEKRVLNQEEMEKVRD
FT                   ENATVMDKARALIDAVIRKGPQACQIFIGHICEDDPHLAETLRLSSGPQSGNFLKTQDS
FT                   QAVVHSSPALQAMPDDLAKLALSGPKVSLKLCSPEVVERIWKEKSAEMYPIMGKSMTRT
FT                   RLALIICNTEFDNLSRRAGAEVDIASMKVLLEGLGYSVEVKENLTALDMTTELKAFAAR
FT                   PEHRSSDSTFLVFMSHGIREGICGKKFSEKVPDVLEVNTIFQIFNTRNCPNLRDKPKVI
FT                   IIQACRGENQGVVWLKDSTGTSGNSSSLAPDDFEDDAIKKAHVEKDFIAFCSSTPDTVS
FT                   WRSPTTGSVFIEKLIENLQEYAWSCDLEEIFRKVRLSFELPDARAQMPTAERVTLTRRF
FT                   YLFPGH"
FT   misc_feature    307..309
FT                   /note="cleavage site"
FT   misc_feature    355..357
FT                   /note="cleavage site"
FT   variation       555
FT                   /replace="a"
FT   variation       607
FT                   /replace="t"
FT   misc_feature    856..858
FT                   /note="Region: catalytic site"
FT   misc_feature    892..894
FT                   /note="cleavage site"
FT   variation       914
FT                   /replace="g"
FT   misc_feature    949..951
FT                   /note="cleavage site"
XX
SQ   Sequence 1218 BP; 351 A; 262 C; 305 G; 300 T; 0 other;
     atggccgaca aggtcctgaa ggaaaagagg aggctgttta tccgctcagt gggcacgggt        60
     acagtaaata gcttgctgga tgaactgtta gagaaaaggg tgctgaacca ggaagagatg       120
     gagaaagtaa gagatgaaaa tgctacagtt atggataagg cccgagcttt gattgatgct       180
     gtcattcgga aagggcccca ggcatgccaa atttttatcg gtcacatttg tgaagatgac       240
     ccccaccttg cagagacact gcgcctatcc tcaggtccac aatctggaaa ttttcttaaa       300
     acacaagact cccaagcagt ggttcattcc tccccagctc ttcaggcaat gccggatgac       360
     ctggctaagc ttgcattgtc agggccaaaa gtgagcctca agctttgttc accagaagtg       420
     gtcgaaagga tatggaaaga aaagtcagca gagatgtacc caataatggg aaagtcgatg       480
     acccgcacac ggcttgcgct cattatctgc aacacagagt ttgacaatct ttccaggaga       540
     gctggagctg aagttgatat tgcaagtatg aaggtgctgc tagaaggtct ggggtacagt       600
     gtggaagtga aagaaaatct caccgctttg gacatgacta cagagctgaa ggcatttgct       660
     gcccgcccag agcaccggtc ctctgacagc actttcctgg tgttcatgtc tcatggtatt       720
     cgagaaggca tttgtgggaa gaaattctct gagaaagtcc cagatgtatt agaagtcaac       780
     accatctttc aaatttttaa caccaggaac tgtccaaatt tgagggacaa acccaaggtg       840
     atcattatcc aggcctgccg tggtgagaat caaggggtag tgtggttaaa agactcaaca       900
     ggaacttctg gaaatagctc ctcactggct ccagacgatt ttgaggatga tgccattaag       960
     aaagcccatg tagagaaaga ttttattgct ttctgctctt caacaccaga tactgtttct      1020
     tggcgaagtc ccacaacggg ctctgttttc attgagaaac tcattgaaaa tttgcaagaa      1080
     tatgcctggt cctgtgatct ggaggaaatt ttccgaaagg tccgattatc atttgagttg      1140
     ccagatgcta gggcacagat gcccactgcc gaaagagtga ctttgacaag acgcttctac      1200
     ctcttcccag gacattaa                                                    1218
//
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