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EBI DbfetchID AF075724; SV 1; linear; genomic DNA; STD; PRO; 2955 BP. XX AC AF075724; S69666; XX DT 27-AUG-1998 (Rel. 56, Created) DT 15-APR-2005 (Rel. 83, Last updated, Version 4) XX DE Legionella pneumophila legiolysin (lly) gene, complete cds; and unknown DE genes. XX KW . XX OS Legionella pneumophila OC Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; OC Legionellaceae; Legionella. XX RN [1] RP 1718-2955 RX PUBMED; 8112844. RA Wintermeyer E., Flugel M., Ott M., Steinert M., Rdest U., Mann K.H., RA Hacker J.; RT "Sequence determination and mutational analysis of the lly locus of RT Legionella pneumophila"; RL Infect. Immun. 62(3):1109-1117(1994). XX RN [2] RP 1-2955 RX DOI; 10.1111/j.1574-6968.2001.tb10818.x RX PUBMED; 11557138. RA Steinert M., Flugel M., Schuppler M., Helbig J.H., Supriyono A., RA Proksch P., Luck P.C.; RT "The Lly protein is essential for p-hydroxyphenylpyruvate dioxygenase RT activity in Legionella pneumophila"; RL FEMS Microbiol. Lett. 203(1):41-47(2001). XX RN [3] RP 1-2955 RA Flugel M., Steinert M., Wintermeyer E., Supriyono A., Proksch P., RA Hacker J.; RT "Homogentisic acid is a product of the p-hydroxyphenylpyruvate dioxigenase RT activity of the Lly-protein, which mediates melanogenesis in Legionella RT pneumophila"; RL Unpublished. XX RN [4] RP 1-2955 RA Steinert M., Flugel M., Wintermeyer E.; RT ; RL Submitted (01-JUL-1998) to the EMBL/GenBank/DDBJ databases. RL NCID/DBMD, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, RL Atlanta, GA 30333, USA XX CC On Aug 26, 1998 this sequence version replaced gi:545640. XX FH Key Location/Qualifiers FH FT source 1..2955 FT /organism="Legionella pneumophila" FT /strain="Philadelphia I" FT /mol_type="genomic DNA" FT /note="derivative JR32" FT /db_xref="taxon:446" FT CDS 45..1118 FT /codon_start=1 FT /transl_table=11 FT /product="unknown" FT /note="ORF2" FT /db_xref="GOA:O85768" FT /db_xref="HSSP:1C1D" FT /db_xref="InterPro:IPR016211" FT /db_xref="UniProtKB/TrEMBL:O85768" FT /protein_id="AAC32841.1" FT /translation="MMSVDNIKNDNQVLAEEDFLEYALSHGFGDLHFKVDPQTGMKAMI FT AIHSTKLGPALGGCRFIEYPNTAAALKDAMRLARGMSFKAASVNLPLGGGKSVIIKPKG FT FFNRAEYMHRFGEFVNELNGRYITALDSGTELSDMDIIAEHTDYVASLSRYNGDPSPST FT SKGVLRGIQAAVAFKLGKDSLKGLHIAIQGLGHVGYALAKQLHELGATLTVADISPAAV FT NMAVQELGAKAVGTDIIHKVPCDVFAPCALGAIINDLTIPQLQTSIIAGAANNQLAHTY FT HGKILHEKGILFAVDYVINAGGLIFAASKYLQTPEDKVSEQIDSIYTSLTEIFTRSAKD FT NLPTSEIADTLAKEKLA" FT CDS 1133..1789 FT /codon_start=1 FT /transl_table=11 FT /product="unknown" FT /note="ORF1" FT /db_xref="GOA:O85769" FT /db_xref="InterPro:IPR018247" FT /db_xref="UniProtKB/TrEMBL:O85769" FT /protein_id="AAC32842.1" FT /translation="MKHLSLTPELYKYLLDISLREHPALAALRKETSTMELANMQVAPE FT QAQFMQMLIRLTRAKKVLELGTFTGYSALAMSLALPDDGQVITCDINEGWTKHAHPYWR FT EAKQEHKIKLRLGPALDTLHSLLNEGGEHQFDFIFIDADKTNYLNYYELALKLVTPKGL FT IAIDNIFWDGKVIDPNDTSGQTREIKKLNQVIKNDSRVFVSLLAIADGMFLVQPI" FT CDS 1856..2902 FT /codon_start=1 FT /transl_table=11 FT /gene="lly" FT /product="legiolysin" FT /function="mediates melanogenesis" FT /db_xref="GOA:Q5ZT84" FT /db_xref="HSSP:1CJX" FT /db_xref="InterPro:IPR004360" FT /db_xref="UniProtKB/Swiss-Prot:Q5ZT84" FT /protein_id="AAC32843.1" FT /translation="MQNNNPCGLDGFAFLEFSGPDRNKLHQQFSEMGFQAVAHHKNQDI FT TLFKQGEIQFIVNAASHCQAEAHASTHGPGACAMGFKVKDAKAAFQHAIAHGGIAFQDA FT PHANHGLPAIQAIGGSVIYFVDEEHQPFSHEWNITSPEPVVGNGLTAIDHLTHNVYRGN FT MDKWASFYASIFNFQEIRFFNIKGKMTGLVSRALGSPCGKIKIPLNESKDDLSQIEEFL FT HEYHGEGIQHIALNTNDIYKTVNGLRKQGVKFLDVPDTYYEMINDRLPWHKEPLNQLHA FT EKILIDGEADPKDGLLLQIFTENIFGPVFFEIIQRKGNQGFGEGNFQALFEAIERDQVR FT RGTLKELS" XX SQ Sequence 2955 BP; 884 A; 559 C; 626 G; 886 T; 0 other; agatctataa cttcttccaa aattattgca agaggagctt aaaaatgatg tctgttgaca 60 atattaaaaa tgataaccag gttttggctg aagaagattt cctcgaatac gcattgtctc 120 atggatttgg tgatttacat tttaaggtgg atccgcaaac ggggatgaag gctatgattg 180 caattcatag caccaagttg ggacctgctt tgggtggttg tcgatttatt gaatatccta 240 atactgctgc tgctttgaag gatgctatgc gccttgccag aggcatgagc tttaaggctg 300 cttcagtcaa tttacctttg ggcggtggaa aatcagttat tattaagcct aaggggtttt 360 ttaatcgagc agaatacatg catcggtttg gtgaattcgt taatgaattg aatggcaggt 420 acatcactgc tttggatagc ggtactgaat taagtgacat ggatattatt gctgagcata 480 ctgactatgt tgccagttta tccagataca atggagatcc ttcaccttct acttccaagg 540 gtgtgttaag agggattcag gctgctgttg cctttaaatt aggtaaagac tctctcaaag 600 gtttgcatat tgctattcag ggtcttggcc acgtcggtta tgctctggca aaacaattac 660 acgaattggg cgcgacatta actgttgctg atatttcacc tgctgctgtg aacatggcgg 720 ttcaagagtt gggagctaaa gcggtcggca ctgacattat ccataaagta ccgtgtgatg 780 tatttgctcc ttgtgcttta ggtgcgatta tcaatgatct tactattccc cagttacaaa 840 ccagtattat tgctggcgct gccaataatc agctcgcaca cacataccat ggcaagattt 900 tacacgaaaa aggcattctg tttgctgtgg attatgtgat taatgcaggt ggtttgatat 960 ttgctgcctc taaatactta caaacgcctg aagacaaggt aagtgagcaa attgatagta 1020 tctatacctc tctgactgaa atttttactc gctctgctaa agataattta cctactagcg 1080 agattgctga tactttggct aaggaaaaat tggcttaatt tggataccgt ttatgaaaca 1140 tttatccctt actcctgagt tgtacaaata cctgcttgat atttccttgc gtgaacatcc 1200 tgctcttgcg gcattacgca aagaaacatc cactatggaa ctcgccaata tgcaggtagc 1260 tccagagcaa gcccaattta tgcagatgct gatacgtttg actcgtgcaa agaaggtatt 1320 ggaacttggg acattcacag gttatagtgc cttggccatg tcccttgctt tgcctgatga 1380 tgggcaagtt atcacctgtg atattaatga gggatggaca aaacatgctc atccttattg 1440 gcgtgaagcc aaacaggaac ataaaattaa attacgcctt ggacctgctc ttgacacttt 1500 acactcatta cttaatgaag gtggagagca tcaatttgat ttcattttta ttgatgctga 1560 caaaactaat tatctgaatt actatgaact ggctttaaaa ttagttacac ctaaaggatt 1620 aattgccata gataatattt tttgggatgg aaaagtaatt gatccgaatg atacgagtgg 1680 acaaaccaga gaaattaaaa aattaaatca agtgattaaa aacgattcaa gggtctttgt 1740 cagtttgtta gctatagctg atgggatgtt tctggtgcaa cccatttaat ctttaaaatc 1800 cccggcaagc aatacactgc attgctatgt aaataagtac aaggagaact tgataatgca 1860 aaataacaac ccctgcggat tagatggctt tgccttttta gagttttcag gccctgatag 1920 gaataaatta catcagcaat tttctgagat ggggtttcag gctgttgccc accataaaaa 1980 tcaagacatt actcttttca aacaagggga aatacaattt atagtgaatg cggcctccca 2040 ttgtcaggca gaagcgcatg cttcaactca tggtccaggc gcttgtgcaa tgggctttaa 2100 agtaaaagat gccaaagccg cttttcaaca cgctatcgcg catggcggta tagcatttca 2160 ggatgcacct catgccaatc acggcttgcc agccatccag gctattggtg gtagtgttat 2220 ttattttgtc gatgaagaac accaaccctt ctctcatgaa tggaatatta cctcaccaga 2280 acccgtagtt ggaaatggtc tgacagcaat cgaccatctc acccataacg tttatcgcgg 2340 taatatggat aaatgggcca gtttctatgc ttccattttt aacttccagg aaattcgttt 2400 tttcaatatc aaaggaaaaa tgacaggttt ggttagtcga gcattaggta gcccttgtgg 2460 caaaatcaaa attcctttaa acgaatccaa agatgattta tcacaaattg aagagtttct 2520 tcatgaatat catggcgagg gcattcaaca catcgctctc aataccaatg atatttataa 2580 aacagtcaac ggcttaagaa aacaaggggt caaattcctg gatgtgccag atacttacta 2640 tgagatgatt aatgaccgcc tcccatggca caaggagcca ctgaatcaac tccatgctga 2700 gaaaatttta attgatggag aagcagatcc caaagacggc ttgttactgc aaatatttac 2760 tgaaaacata tttggaccag tcttttttga aattattcaa cgcaaaggca atcaggggtt 2820 tggtgaaggg aatttccagg ctctattcga agctattgaa agagatcaag ttcgacgtgg 2880 tactttaaaa gaattaagct agacaaacag ttgaaatgta atgatgctgt ttttcaggca 2940 taagccagga gatct 2955 // |
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