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EBI DbfetchID AF053121; SV 1; linear; genomic DNA; STD; PRO; 2685 BP. XX AC AF053121; X95718; XX DT 17-JUN-1998 (Rel. 56, Created) DT 15-APR-2005 (Rel. 83, Last updated, Version 4) XX DE Streptococcus pneumoniae DNA gyrase subunit A (gyrA) gene, complete cds. XX KW . XX OS Streptococcus pneumoniae OC Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus. XX RN [1] RP 262-642 RX PUBMED; 8891124. RA Munoz R., De La Campa A.G.; RT "ParC subunit of DNA topoisomerase IV of Streptococcus pneumoniae is a RT primary target of fluoroquinolones and cooperates with DNA gyrase A subunit RT in forming resistance phenotype"; RL Antimicrob. Agents Chemother. 40(10):2252-2257(1996). XX RN [2] RP 1-2685 RX PUBMED; 9603872. RA Balas D., Fernandez-Moreira E., De La Campa A.G.; RT "Molecular characterization of the gene encoding the DNA gyrase A subunit RT of Streptococcus pneumoniae"; RL J. Bacteriol. 180(11):2854-2861(1998). XX RN [3] RP 1-2685 RA Balas D., Fernandez-Moreira E., De La Campa A.G.; RT ; RL Submitted (10-MAR-1998) to the EMBL/GenBank/DDBJ databases. RL Unidad de Genetica Bacteriana, CNBF Instituto de Salud Carlos III, RL Carretera A. Pozuelo KM. 2, 28220 Majadahonda, Madrid, Spain XX CC On Jun 16, 1998 this sequence version replaced gi:1495796. XX FH Key Location/Qualifiers FH FT source 1..2685 FT /organism="Streptococcus pneumoniae" FT /strain="R6" FT /mol_type="genomic DNA" FT /db_xref="taxon:1313" FT -35_signal 68..72 FT /gene="gyrA" FT -10_signal 85..95 FT /gene="gyrA" FT /note="-10 extended region" FT misc_feature 106 FT /gene="gyrA" FT /note="transcription start site" FT RBS 115..123 FT /gene="gyrA" FT CDS 133..2601 FT /codon_start=1 FT /transl_table=11 FT /gene="gyrA" FT /product="DNA gyrase subunit A" FT /db_xref="GOA:Q8DPM2" FT /db_xref="HSSP:1AB4" FT /db_xref="InterPro:IPR013757" FT /db_xref="UniProtKB/Swiss-Prot:Q8DPM2" FT /protein_id="AAC23563.1" FT /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHRR FT ILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVDGH FT GNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPARFPN FT LLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTGALVM FT GKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVRLVQEK FT RIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAIQNGIPK FT ILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIRIIRASET FT DAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIADLADILAKP FT ERVSQIIKDELDEVKRKFSDKRRTELMVGQVLSLEDEDLIEESDVLITLSNRGYIKRLD FT QDEFTAQKRGGRGVQGTGVEDDDFVRELVSTSTHDHLLFFTNKGRVYRLKGYEIPEYGR FT TAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHVLLKRTSVKEFANIRQNG FT LKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRIATGVKGVNLREG FT DTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAKITEKNGLLAGLMT FT VQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQIVTFTTVAVAEKEEV FT GTENETEGEA" FT misc_feature 262..642 FT /gene="gyrA" FT /note="encodes quinolone-resistance determining region" XX SQ Sequence 2685 BP; 793 A; 481 C; 649 G; 762 T; 0 other; ttttaaaaaa ctttgtcacg aatatgcctt atagttctcg atgtaaacgt tttagtggtt 60 tagaggctga aatagacggg aatttatggt ataatgttgt tacttactaa ttgtgaaatg 120 aggcatttat taatgcagga taaaaattta gtgaatgtca atctgacaaa ggagatgaag 180 gcaagtttta tcgactacgc catgagtgtt atcgtagcgc gagctcttcc tgatgttcga 240 gatggcttaa aacctgttca ccgtcgcatt ctctacggaa tgaatgaatt gggtgtgacc 300 ccagacaaac cccataaaaa atctgctcgt attacagggg atgtcatggg taaataccac 360 ccacacgggg attcctctat ttatgaagcc atggtccgta tggctcaatg gtggagctac 420 cgttacatgc ttgtagatgg tcatgggaat tttggttcca tggatggaga tagtgctgcc 480 gctcaacgtt ataccgaggc acgtatgagc aagattgctc tggaaatgct tcgtgatatc 540 aacaaaaata cagttgattt cgttgataac tatgatgcca atgaacggga acccttggtc 600 ttgccagcgc gttttccaaa ccttttggtt aatggagcaa ctggtatcgc ggttgggatg 660 gcaaccaata ttccacctca taatctgggt gaaaccattg atgcagtgaa gttggtcatg 720 gataatcctg aagtgactac caaggacttg atggaagtct tgcctggacc agattttcca 780 actggtgctc ttgtcatggg gaaatcaggt atccataagg cttatgaaac aggtaaaggt 840 tcgattgtcc tacgttctcg tacagagatt gaaacgacta agactggtcg tgagcgtatc 900 gttgtaacag aatttcctta catggtcaat aaaaccaagg tgcatgagca tattgttcgc 960 ttggttcagg aaaaacgcat tgagggtatc acagcagtac gtgatgagtc aaaccgtgaa 1020 ggtgttcgat ttgttattga agtcaagcgc gacgcctcag ccaatgttat tctcaataac 1080 ctcttcaaaa tgacccaaat gcaaaccaat tttggtttca atatgctcgc tatccaaaat 1140 ggtataccga aaattttgtc tcttcgtcag attttggatg cttatattga gcaccaaaaa 1200 gaagtggttg ttcgtcgtac acgttttgat aaggaaaaag cggaagcgcg cgctcatatc 1260 ttagaaggtc tcttgattgc gctagaccat atcgacgaag tgattcgtat catccgtgct 1320 agtgaaacgg atgcggaagc tcaagctgag ttgatgagca agtttaagct ttctgaacgt 1380 caaagtcaag ctatccttga tatgcgtctt cgccgtttga caggtttgga acgcgataag 1440 attcaatctg agtatgatga cctcttggct ctgattgcgg atttagcaga tattcttgct 1500 aagcctgaac gtgtttctca aattatcaaa gacgaattgg atgaagttaa acgtaaattt 1560 tctgataaac gccgtacaga gttgatggtt ggacaggtct tgagtctcga ggatgaggac 1620 ttgattgaag aatcggatgt cttgattacc ctttctaaca gaggctacat taagcgtttg 1680 gatcaggacg agttcactgc tcaaaaacgt gggggtcgtg gtgtccaagg aacgggagta 1740 gaagatgatg actttgttcg tgagttagtg tcaactagta cccatgatca tctgctcttc 1800 ttcacaaaca agggacgtgt ctatcgtctt aaaggttatg aaattcctga gtatggtcgg 1860 actgccaaag ggctaccagt agtcaatctc ttgaaattgg atgaagacga aagtattcag 1920 acggttatca atgttgagtc tgatcgcagt gatgatgctt atctcttctt tacaacccgt 1980 cacgtattgt tgaagagaac cagtgttaag gagtttgcca atattcgtca aaatggtctc 2040 aaagcgctga atttaaagga tgaagatgag ttaatcaatg tcttgttggc agaaggagat 2100 atggatatta tcattggtac caagtttggt tatgcagttc gctttaatca atcagccgtt 2160 cgtggtatga gccgtatcgc cactggtgtg aaaggtgtta accttcgtga aggagacaca 2220 gttgttggtg ccagcttgat tactgatcaa gatgaggttc ttattatcac agaaaaagga 2280 tatggtaagc gtacagtcgc tactgaatac ccaacaaaag gtcgtggtgg taagggaatg 2340 cagacagcta aaattaccga aaaaaatggc ttgctggccg gtcttatgac tgttcaaggg 2400 gatgaggatt tgatgattat cactgataca ggtgtcatga ttcgaaccaa tcttgccaat 2460 atttcacaaa caggacgtgc aactatggga gttaaagtaa tgcgcctgga tcaagatgct 2520 cagatagtga ctttcacaac ggttgcggtg gcagaaaaag aagaagttgg gacagaaaac 2580 gaaacagaag gtgaagcata atgtctcaaa aaaataataa aaagaaaaac aagcgaaaaa 2640 atctgctgac aaatatccta gcaggatttc tgatattact gtcac 2685 // |
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